Pseudomonas mendocina ymp, complete genome NC_009439 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 146308763 Common - putative transcriptional regulator, GntR family Pmen_3748 165 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 146309242 Common - conserved hypothetical protein 156 Pmen_4228 28 COG3111 COG3111, Uncharacterized conserved protein Function unknown 146306196 Common - transposase IS66 Pmen_1163 67 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 146305524 Common - glycine betaine/L-proline ABC transporter, ATPase subunit Pmen_0487 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 146309093 Common - acyl-CoA dehydrogenase domain protein Pmen_4079 151 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 146307001 Common - hypothetical protein Pmen_1973 12 None None None 146308513 Common - hypothetical protein Pmen_3498 54 COG2976 COG2976, Uncharacterized protein conserved in bacteria Function unknown 146309323 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) Pmen_4309 197 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 146305154 Common - hypothetical protein Pmen_0113 3 None None None 146305804 Common - membrane protein-like protein Pmen_0769 14 COG3235 COG3235, Predicted membrane protein Function unknown 146307642 Common - transcriptional regulator, TetR family Pmen_2619 25 COG1309 AcrR, Transcriptional regulator Transcription 146307474 Common - methyl-accepting chemotaxis sensory transducer Pmen_2451 143 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146306877 Common - N-ethylammeline chlorohydrolase Pmen_1846 175 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 146308880 Common - hypothetical protein Pmen_3866 21 COG3495 COG3495, Uncharacterized protein conserved in bacteria Function unknown 146306965 Common - hypothetical protein Pmen_1936 27 COG4544 COG4544, Uncharacterized conserved protein Function unknown 146306946 Common fadE acyl-CoA dehydrogenase Pmen_1917 156 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 146305787 Common - oxidoreductase FAD/NAD(P)-binding domain protein Pmen_0752 110 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 146307498 Common - sulfatase Pmen_2475 69 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 146307093 Common - hypothetical protein Pmen_2065 62 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 146306716 Common - hypothetical protein Pmen_1685 1 None None None 146305439 Common - Holliday junction resolvase-like protein Pmen_0399 173 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 146305576 Common - peptidase M48, Ste24p Pmen_0539 124 COG4784 COG4784, Putative Zn-dependent protease General function prediction only 146308180 Common - NAD(P)H dehydrogenase (quinone) Pmen_3160 91 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 146305501 Pathogen - hypothetical protein Pmen_0464 1 None None None 146306549 Common - arsenical-resistance protein Pmen_1518 131 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 146308368 Common - bacterioferritin Pmen_3349 107 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 146308577 Common - acyl-CoA synthetase Pmen_3562 222 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 146306483 Common - glyceraldehyde-3-phosphate dehydrogenase, type I Pmen_1451 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 146305127 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Pmen_0086 66 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 146307721 Common - RNA polymerase sigma factor Pmen_2699 150 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 146308984 Common - phage major capsid protein, HK97 family Pmen_3970 53 COG4653 COG4653, Predicted phage phi-C31 gp36 major capsid-like protein General function prediction only 146307069 Common - GAF modulated sigma54 specific transcriptional regulator, Fis family Pmen_2041 173 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 146308563 Common - Aminopeptidase Y Pmen_3548 51 COG2234 Iap, Predicted aminopeptidases General function prediction only 146307611 Pathogen - hypothetical protein Pmen_2588 1 None None None 146305794 Common glyA serine hydroxymethyltransferase Pmen_0759 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 146307672 Common - methyl-accepting chemotaxis sensory transducer Pmen_2650 146 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146308736 Common - GCN5-related N-acetyltransferase Pmen_3721 81 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 146309477 Pathogen - hypothetical protein Pmen_4463 1 None None None 146307702 Common - short chain dehydrogenase Pmen_2680 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 146306951 Common - acriflavin resistance protein Pmen_1922 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 146307340 Common - hypothetical protein Pmen_2315 22 COG3913 SciT, Uncharacterized protein conserved in bacteria Function unknown 146305072 Pathogen - HrpZ family protein Pmen_0030 1 COG4964 CpaC, Flp pilus assembly protein, secretin CpaC Intracellular trafficking and secretion 146305308 Common - diaminopimelate decarboxylase Pmen_0267 218 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 146305810 Common - type IV-A pilus assembly ATPase PilB Pmen_0775 216 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 146307485 Common - transcriptional regulator, AraC family Pmen_2462 124 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 146305854 Common - hypothetical protein Pmen_0819 3 None None None 146306687 Pathogen - hypothetical protein Pmen_1656 1 None None None 146307820 Common - Cobyrinic acid a,c-diamide synthase Pmen_2798 202 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 146308678 Common - Lysine exporter protein (LYSE/YGGA) Pmen_3663 113 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 146308586 Common - transcriptional regulator, LysR family Pmen_3571 149 COG0583 LysR, Transcriptional regulator Transcription 146309173 Common - coproporphyrinogen III oxidase Pmen_4159 205 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 146306085 Common - hypothetical protein Pmen_1051 14 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 146309217 Common - binding-protein-dependent transport systems inner membrane component Pmen_4203 220 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 146305895 Common - ribonuclease, Rne/Rng family Pmen_0860 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 146307882 Common - ABC transporter related Pmen_2860 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 146309252 Common - hypothetical protein Pmen_4238 5 None None None 146308013 Common - membrane protein-like protein Pmen_2991 1 COG3308 COG3308, Predicted membrane protein Function unknown 146308197 Common - hypothetical protein Pmen_3177 1 None None None 146306109 Common - FAD dependent oxidoreductase Pmen_1075 42 COG3380 COG3380, Predicted NAD/FAD-dependent oxidoreductase General function prediction only 146306937 Common - erythronate-4-phosphate dehydrogenase Pmen_1908 226 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 146309465 Common - methyl-accepting chemotaxis sensory transducer Pmen_4451 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146308305 Common - hypothetical protein Pmen_3285 1 None None None 146307595 Common - glutaminyl-tRNA synthetase Pmen_2572 237 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 146306956 Common - VacJ family lipoprotein Pmen_1927 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 146305756 Common - Hemolysin-type calcium-binding region Pmen_0721 105 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 146307692 Common - Glutathione S-transferase, N-terminal domain Pmen_2670 102 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 146309038 Common - hypothetical protein Pmen_4024 150 COG0344 COG0344, Predicted membrane protein Function unknown 146306498 Common - L-aspartate oxidase Pmen_1466 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 146309229 Common - protein of unknown function DUF81 Pmen_4215 100 COG0730 COG0730, Predicted permeases General function prediction only 146307471 Common - transglutaminase domain protein Pmen_2448 97 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 146307778 Common - Xanthine/uracil/vitamin C permease Pmen_2756 145 COG2252 COG2252, Permeases General function prediction only 146308304 Common - putative PAS/PAC sensor protein Pmen_3284 103 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 146306134 Common - short-chain dehydrogenase/reductase SDR Pmen_1100 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 146308695 Common obgE GTPase ObgE Pmen_3680 249 COG0536 Obg, Predicted GTPase General function prediction only 146308396 Common - putative transcriptional regulator Pmen_3377 24 COG5631 COG5631, Predicted transcription regulator, contains HTH domain (MarR family) Transcription 146306180 Common - protein of unknown function DUF181 Pmen_1146 53 COG1944 COG1944, Uncharacterized conserved protein Function unknown 146306928 Pathogen - hypothetical protein Pmen_1899 1 None None None 146308744 Common - DNA polymerase III, epsilon subunit Pmen_3729 186 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 146305269 Common - hypothetical protein Pmen_0228 43 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 146307623 Common - cytochrome c oxidase, cbb3-type, subunit II Pmen_2600 82 COG2993 CcoO, Cbb3-type cytochrome oxidase, cytochrome c subunit Energy production and conversion 146308493 Common - regulatory protein, IclR Pmen_3476 118 COG1414 IclR, Transcriptional regulator Transcription 146305967 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein Pmen_0932 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 146308387 Common - hypothetical protein Pmen_3368 1 None None None 146309541 Pathogen - hypothetical protein Pmen_4527 4 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 146307621 Common - hydrolase of the alpha/beta-hydrolase fold-like protein Pmen_2598 37 COG3571 COG3571, Predicted hydrolase of the alpha/beta-hydrolase fold General function prediction only 146309614 Common - transposase IS3/IS911 family protein Pmen_4601 78 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 146308314 Common - branched-chain amino acid transport Pmen_3294 7 COG4392 COG4392, Predicted membrane protein Function unknown 146309441 Common - hypothetical protein Pmen_4427 1 None None None 146308218 Common - ABC transporter related Pmen_3198 249 COG3638 COG3638, ABC-type phosphate/phosphonate transport system, ATPase component Inorganic ion transport and metabolism 146306322 Common - protein of unknown function DUF6, transmembrane Pmen_1290 68 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 146308935 Common nusG transcription antitermination protein NusG Pmen_3921 215 COG0250 NusG, Transcription antiterminator Transcription 146307922 Common - hypothetical protein Pmen_2900 1 None None None 146305497 Common pgk phosphoglycerate kinase Pmen_0460 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 146308223 Pathogen - hypothetical protein Pmen_3203 2 None None None 146305728 Common ureB urease subunit beta Pmen_0693 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 146306311 Common - Tetratricopeptide TPR_2 repeat protein Pmen_1279 100 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 146305820 Common - DNA-binding transcriptional regulator FruR Pmen_0785 124 COG1609 PurR, Transcriptional regulators Transcription 146308481 Common - small multidrug resistance protein Pmen_3464 147 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 146308393 Common - sulfate transporter Pmen_3374 160 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 146305310 Common cyaY frataxin-like protein Pmen_0269 44 COG1965 CyaY, Protein implicated in iron transport, frataxin homolog Inorganic ion transport and metabolism 146306318 Common - hypothetical protein Pmen_1286 1 None None None 146307560 Common - hypothetical protein Pmen_2537 3 None None None 146308342 Common - Superoxide dismutase Pmen_3322 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 146305184 Common - Cytochrome-c oxidase Pmen_0143 174 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 146307903 Common - phosphonate C-P lyase system protein PhnL Pmen_2881 249 COG4778 PhnL, ABC-type phosphonate transport system, ATPase component Inorganic ion transport and metabolism 146309045 Common - transcriptional regulator, XRE family Pmen_4031 7 COG1396 HipB, Predicted transcriptional regulators Transcription 146308187 Common - Antibiotic biosynthesis monooxygenase Pmen_3167 51 COG1359 COG1359, Uncharacterized conserved protein Function unknown 146308780 Common - transcriptional regulator, TetR family Pmen_3765 53 COG1309 AcrR, Transcriptional regulator Transcription 146306994 Common - pyrroloquinoline quinone biosynthesis protein PqqB Pmen_1966 34 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 146308135 Common - Substrate-binding region of ABC-type glycine betaine transport system Pmen_3115 90 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 146306275 Common - hypothetical protein Pmen_1243 12 None None None 146309125 Common - helicase c2 Pmen_4111 74 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 146309545 Common - hypothetical protein Pmen_4531 2 None None None 146309361 Common - sulfate ABC transporter, inner membrane subunit CysW Pmen_4347 221 COG4208 CysW, ABC-type sulfate transport system, permease component Inorganic ion transport and metabolism 146305753 Common - type I secretion outer membrane protein, TolC family Pmen_0718 73 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 146305927 Common - protein of unknown function DUF1043 Pmen_0892 13 COG3105 COG3105, Uncharacterized protein conserved in bacteria Function unknown 146305596 Common - potassium efflux protein KefA Pmen_0559 224 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 146305287 Common - Endoribonuclease L-PSP Pmen_0246 147 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 146305485 Common - 5,10-methylenetetrahydrofolate reductase Pmen_0448 146 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 146306402 Pathogen - protein of unknown function DUF1145 Pmen_1370 1 COG3776 COG3776, Predicted membrane protein Function unknown 146306296 Common - diguanylate cyclase Pmen_1264 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 146307735 Common - Sporulation domain protein Pmen_2713 6 COG3147 DedD, Uncharacterized protein conserved in bacteria Function unknown 146307012 Common - competence protein ComEA helix-hairpin-helix repeat protein Pmen_1984 93 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 146309387 Common rpmG 50S ribosomal protein L33 Pmen_4373 141 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 146305588 Common gltD glutamate synthase subunit beta Pmen_0551 196 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 146306465 Common - NADH dehydrogenase (quinone) Pmen_1433 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 146308143 Common - DGPFAETKE family protein Pmen_3123 46 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 146305215 Pathogen - hypothetical protein Pmen_0174 1 None None None 146305998 Common - Tfp pilus assembly protein FimT-like protein Pmen_0963 5 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 146308920 Common rplB 50S ribosomal protein L2 Pmen_3906 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 146306384 Common - MscS Mechanosensitive ion channel Pmen_1352 227 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 146308805 Common - lytic murein transglycosylase Pmen_3790 107 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 146307329 Common - Hemerythrin HHE cation binding domain protein Pmen_2304 17 COG2846 COG2846, Regulator of cell morphogenesis and NO signaling Cell division and chromosome partitioning 146305832 Common - periplasmic binding protein Pmen_0797 28 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 146308142 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pmen_3122 72 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 146309372 Common - sigma54 specific transcriptional regulator, Fis family Pmen_4358 171 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 146308234 Common - AraC-type transcriptional regulator domain protein Pmen_3214 90 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 146305708 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Pmen_0673 70 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 146309017 Common - spermidine/putrescine ABC transporter ATPase subunit Pmen_4003 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 146307120 Common - OmpF family protein Pmen_2092 161 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 146308740 Common - CheC, inhibitor of MCP methylation Pmen_3725 173 COG1776 CheC, Chemotaxis protein CheC, inhibitor of MCP methylation Cell motility and secretion / Signal transduction mechanisms 146309264 Common - ABC-type amino acid transport/signal transduction systems periplasmic component/domain-like protein Pmen_4250 20 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146309157 Common - signal transduction histidine kinase, nitrogen specific, NtrB Pmen_4143 220 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 146305104 Common - Substrate-binding region of ABC-type glycine betaine transport system Pmen_0063 65 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 146307113 Common - phosphoenolpyruvate synthase Pmen_2085 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 146307186 Common metH B12-dependent methionine synthase Pmen_2159 178 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 146308620 Common rpsO 30S ribosomal protein S15 Pmen_3605 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 146307825 Common - chemotaxis phosphatase, CheZ Pmen_2803 45 COG3143 CheZ, Chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146307555 Common - Sterol-binding domain protein Pmen_2532 21 COG3255 COG3255, Putative sterol carrier protein Lipid metabolism 146306420 Common - Uncharacterized small conserved protein-like protein Pmen_1388 10 COG5626 COG5626, Uncharacterized small conserved protein Function unknown 146306597 Common - putative CheW protein Pmen_1566 124 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 146308567 Common - Glutathione S-transferase-like protein Pmen_3552 15 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 146307969 Common - 1-aminocyclopropane-1-carboxylate deaminase-like protein Pmen_2947 18 COG2515 Acd, 1-aminocyclopropane-1-carboxylate deaminase Amino acid transport and metabolism 146305647 Common - transcriptional regulator, LysR family Pmen_0612 166 COG0583 LysR, Transcriptional regulator Transcription 146306614 Common - DNA topoisomerase I Pmen_1583 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 146308413 Common - homoserine dehydrogenase Pmen_3394 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 146307313 Common - glycogen/starch/alpha-glucan phosphorylase Pmen_2288 141 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 146307308 Common - Alcohol dehydrogenase GroES domain protein Pmen_2283 209 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 146307103 Common - aminoglycoside phosphotransferase Pmen_2075 59 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 146308907 Common rplR 50S ribosomal protein L18 Pmen_3893 215 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 146308008 Common - hypothetical protein Pmen_2986 1 None None None 146307053 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Pmen_2025 95 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 146305581 Common - Pilus assembly protein, PilO Pmen_0544 46 COG3167 PilO, Tfp pilus assembly protein PilO Cell motility and secretion / Intracellular trafficking and secretion 146306923 Common - protein of unknown function DUF1260 Pmen_1893 4 None None None 146306442 Common nadE NAD synthetase Pmen_1410 216 COG0171 NadE, NAD synthase Coenzyme metabolism 146308102 Common - hypothetical protein Pmen_3081 4 None None None 146307871 Common flgC flagellar basal body rod protein FlgC Pmen_2849 126 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 146306674 Common - GCN5-related N-acetyltransferase Pmen_1643 81 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 146305204 Common - uracil-xanthine permease Pmen_0163 123 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 146306283 Common - hypothetical protein Pmen_1251 36 COG4628 COG4628, Uncharacterized conserved protein Function unknown 146308889 Common - dTDP-4-dehydrorhamnose reductase Pmen_3875 114 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 146307454 Common - efflux transporter, RND family, MFP subunit Pmen_2431 164 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 146308109 Common - hypothetical protein Pmen_3088 2 None None None 146307294 Common - membrane protein-like protein Pmen_2269 35 COG3336 COG3336, Predicted membrane protein Function unknown 146309013 Common - ribulose-phosphate 3-epimerase Pmen_3999 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 146309530 Common - hypothetical protein Pmen_4516 7 None None None 146306250 Common - Galactarate dehydratase Pmen_1218 73 COG2721 UxaA, Altronate dehydratase Carbohydrate transport and metabolism 146305312 Common - nucleoside diphosphate kinase regulator Pmen_0271 66 COG0782 GreA, Transcription elongation factor Transcription 146306900 Common - dTDP-4-dehydrorhamnose reductase Pmen_1870 135 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 146309449 Common - protein of unknown function DUF1127 Pmen_4435 2 COG5457 COG5457, Uncharacterized conserved small protein Function unknown 146308772 Common - CRISPR-associated protein Cas5 family Pmen_3757 33 None None None 146309500 Common - glucose-6-phosphate 1-dehydrogenase Pmen_4486 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 146305054 Common - D,D-heptose 1,7-bisphosphate phosphatase Pmen_0012 122 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 146307582 Common - ABC transporter related Pmen_2559 249 COG4181 COG4181, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 146307593 Common - TonB-dependent receptor Pmen_2570 116 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 146308877 Common - hypothetical protein Pmen_3863 6 None None None 146307602 Common - protein of unknown function DUF903 Pmen_2579 14 None None None 146305661 Common - ribosome-associated GTPase Pmen_0626 163 COG1162 COG1162, Predicted GTPases General function prediction only 146305677 Common - methyl-accepting chemotaxis sensory transducer Pmen_0642 91 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146308945 Common - protein of unknown function DUF583 Pmen_3931 71 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 146307879 Common - major facilitator superfamily MFS_1 Pmen_2857 62 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 146308601 Common - glutamyl-Q tRNA(Asp) synthetase Pmen_3586 248 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 146305335 Common - protein of unknown function DUF188 Pmen_0294 96 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 146306257 Common - helix-turn-helix- domain containing protein, AraC type Pmen_1225 142 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 146307962 Common - hypothetical protein Pmen_2940 20 None None None 146307722 Common - von Willebrand factor, type A Pmen_2700 65 COG2304 COG2304, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 146305399 Common ompR osmolarity response regulator Pmen_0359 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 146307018 Common - 6-pyruvoyl tetrahydropterin synthase and hypothetical protein Pmen_1990 132 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 146307038 Common - D-cysteine desulfhydrase Pmen_2010 69 COG2515 Acd, 1-aminocyclopropane-1-carboxylate deaminase Amino acid transport and metabolism 146308488 Common - Methylenetetrahydrofolate dehydrogenase (NADP(+)) Pmen_3471 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 146309626 Common - F0F1 ATP synthase subunit A Pmen_4613 205 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 146307334 Common - 17 kDa surface antigen Pmen_2309 1 COG3133 SlyB, Outer membrane lipoprotein Cell envelope biogenesis, outer membrane 146308507 Common - 2-isopropylmalate synthase Pmen_3492 210 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 146308981 Pathogen - hypothetical protein Pmen_3967 1 None None None 146306244 Common - hypothetical protein Pmen_1212 2 None None None 146305175 Common - helix-turn-helix domain protein Pmen_0134 11 None None None 146309119 Common - alpha-1,6-glucosidase, pullulanase-type Pmen_4105 118 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 146309517 Common - ABC transporter related Pmen_4503 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 146306186 Common - binding-protein-dependent transport systems inner membrane component Pmen_1152 152 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 146305091 Common - hypothetical protein Pmen_0050 72 COG1738 COG1738, Uncharacterized conserved protein Function unknown 146307609 Pathogen - hypothetical protein Pmen_2586 1 None None None 146306774 Common mobA molybdopterin-guanine dinucleotide biosynthesis protein A Pmen_1743 122 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 146306214 Common - hypothetical protein Pmen_1182 9 None None None 146309592 Common - short-chain dehydrogenase/reductase SDR Pmen_4578 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 146305627 Common - glycosyl transferase, family 2 Pmen_0590 197 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 146308942 Common - peptidase M23B Pmen_3928 187 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 146307795 Common - pyruvate kinase Pmen_2773 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 146307758 Common - drug resistance transporter, EmrB/QacA subfamily Pmen_2736 187 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 146306541 Common - short-chain dehydrogenase/reductase SDR Pmen_1509 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 146308426 Common - protein of unknown function DUF1289 Pmen_3407 39 COG3313 COG3313, Predicted Fe-S protein General function prediction only 146308333 Common - hypothetical protein Pmen_3313 4 None None None 146305098 Common - DNA protecting protein DprA Pmen_0057 209 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 146306220 Common - phage integrase family protein Pmen_1188 115 COG0582 XerC, Integrase DNA replication, recombination, and repair 146308287 Common - protein of unknown function DUF1028 Pmen_3267 39 COG3342 COG3342, Uncharacterized conserved protein Function unknown 146305371 Common gcvT glycine cleavage system aminomethyltransferase T Pmen_0331 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 146306749 Common - protein of unknown function DUF202 Pmen_1718 19 COG2149 COG2149, Predicted membrane protein Function unknown 146306128 Common - cationic amino acid ABC transporter, periplasmic binding protein Pmen_1094 176 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146309194 Common - alpha/beta hydrolase fold Pmen_4180 69 COG0429 COG0429, Predicted hydrolase of the alpha/beta-hydrolase fold General function prediction only 146307829 Common flhF flagellar biosynthesis regulator FlhF Pmen_2807 247 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 146308628 Common - phosphoglucosamine mutase Pmen_3613 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 146307965 Common - metallophosphoesterase Pmen_2943 78 None None None 146306713 Common - transcriptional regulator, LysR family Pmen_1682 180 COG0583 LysR, Transcriptional regulator Transcription 146306288 Common - aldo/keto reductase Pmen_1256 180 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 146306294 Common - hypothetical protein Pmen_1262 2 COG2900 SlyX, Uncharacterized protein conserved in bacteria Function unknown 146306726 Common - ABC transporter related Pmen_1695 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 146305476 Common - AMP-dependent synthetase and ligase Pmen_0437 222 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 146305871 Common - response regulator receiver protein Pmen_0836 224 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 146308213 Common - hypothetical protein Pmen_3193 4 None None None 146308866 Common - thiamine monophosphate kinase Pmen_3852 183 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 146306281 Common - protein of unknown function DUF482 Pmen_1249 81 COG3146 COG3146, Uncharacterized protein conserved in bacteria Function unknown 146308559 Common - amino acid permease-associated region Pmen_3544 166 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 146305148 Common - Rhs element Vgr protein Pmen_0107 60 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 146308532 Common secF preprotein translocase subunit SecF Pmen_3517 207 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 146307843 Common fliJ flagellar biosynthesis chaperone Pmen_2821 34 COG2882 FliJ, Flagellar biosynthesis chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 146308461 Common - NUDIX hydrolase Pmen_3444 140 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 146306705 Common - hypothetical protein Pmen_1674 3 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 146307728 Common - electron transfer flavoprotein, alpha subunit Pmen_2706 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 146308729 Common - transcriptional regulator, TetR family Pmen_3714 70 COG1309 AcrR, Transcriptional regulator Transcription 146305162 Common - hypothetical protein Pmen_0121 3 None None None 146308349 Common - putative transcriptional regulator, MerR family Pmen_3330 10 COG0789 SoxR, Predicted transcriptional regulators Transcription 146309075 Common - Biopolymer transport protein ExbD/TolR Pmen_4061 129 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 146307384 Common - hypothetical protein Pmen_2359 5 None None None 146305654 Common - response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) Pmen_0619 165 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 146307261 Common - heavy metal sensor signal transduction histidine kinase Pmen_2235 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146308870 Common - riboflavin synthase subunit alpha Pmen_3856 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 146307077 Common tig trigger factor Pmen_2049 215 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 146305950 Common - cell division protein FtsL Pmen_0915 37 COG3116 FtsL, Cell division protein Cell division and chromosome partitioning 146305682 Common - hypothetical protein Pmen_0647 9 None None None 146306896 Pathogen - hypothetical protein Pmen_1865 1 None None None 146309481 Common - helix-turn-helix- domain containing protein, AraC type Pmen_4467 116 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 146309507 Common - protein of unknown function DUF323 Pmen_4493 89 COG1262 COG1262, Uncharacterized conserved protein Function unknown 146305404 Common - protein of unknown function DUF785 Pmen_0364 39 COG4067 COG4067, Uncharacterized protein conserved in archaea Posttranslational modification, protein turnover, chaperones 146309368 Common - hypothetical protein Pmen_4354 22 None None None 146305255 Common - Lytic transglycosylase, catalytic Pmen_0214 153 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 146305842 Common - hypothetical protein Pmen_0807 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 146309574 Common - TRAP transporter solute receptor, TAXI family Pmen_4560 88 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 146306161 Common - hypothetical protein Pmen_1127 3 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 146308024 Common - hypothetical protein Pmen_3002 1 None None None 146309222 Common - protein of unknown function DUF161 Pmen_4208 55 COG1284 COG1284, Uncharacterized conserved protein Function unknown 146306017 Common - hypothetical protein Pmen_0982 4 None None None 146306805 Common - protein of unknown function DUF709 Pmen_1774 35 COG3100 COG3100, Uncharacterized protein conserved in bacteria Function unknown 146307254 Common - chromate transporter, chromate ion transporter (CHR) family Pmen_2228 114 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 146309349 Common - Rhodanese domain protein Pmen_4335 145 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 146305049 Common - hypothetical protein Pmen_0007 1 None None None 146305167 Common - Dipeptidyl aminopeptidase/acylaminoacyl-peptidase-like protein Pmen_0126 13 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 146306305 Common - 4-hydroxybenzoyl-CoA thioesterase Pmen_1273 141 COG0824 FcbC, Predicted thioesterase General function prediction only 146305860 Common - efflux transporter, RND family, MFP subunit Pmen_0825 160 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 146306427 Common - lactoylglutathione lyase Pmen_1395 140 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 146309284 Common - extracellular solute-binding protein, family 3 Pmen_4270 175 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146308703 Common groEL chaperonin GroEL Pmen_3688 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 146309203 Common - glucose-methanol-choline oxidoreductase Pmen_4189 77 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 146307912 Common - phosphonate ABC transporter, ATPase subunit Pmen_2890 249 COG3638 COG3638, ABC-type phosphate/phosphonate transport system, ATPase component Inorganic ion transport and metabolism 146305689 Common - hypothetical protein Pmen_0654 12 None None None 146309590 Common - Lysine exporter protein (LYSE/YGGA) Pmen_4576 126 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 146308958 Common trpC indole-3-glycerol-phosphate synthase Pmen_3944 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 146306067 Common - hypothetical protein Pmen_1032 80 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 146307751 Common - thioesterase superfamily protein Pmen_2729 33 COG0824 FcbC, Predicted thioesterase General function prediction only 146308116 Common - putative transcriptional regulator, GntR family Pmen_3095 219 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 146307768 Common ligA NAD-dependent DNA ligase LigA Pmen_2746 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 146305744 Common fis DNA-binding protein Fis Pmen_0709 95 COG2901 Fis, Factor for inversion stimulation Fis, transcriptional activator Transcription / DNA replication, recombination, and repair 146308200 Common - hypothetical protein Pmen_3180 1 None None None 146306618 Common - LexA repressor Pmen_1587 173 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 146309534 Common - hypothetical protein Pmen_4520 2 None None None 146306365 Common - transcriptional regulator, GntR family Pmen_1333 118 COG2188 PhnF, Transcriptional regulators Transcription 146306504 Common - GTP-binding protein LepA Pmen_1472 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 146307863 Common flgK flagellar hook-associated protein FlgK Pmen_2841 123 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 146307701 Common - Bile acid:sodium symporter Pmen_2679 76 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 146306360 Common - ABC transporter related Pmen_1328 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 146308632 Common - protein of unknown function UPF0044 Pmen_3617 90 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 146305984 Common - hypothetical protein Pmen_0949 6 None None None 146305417 Common - ATP/ADP translocase-like protein Pmen_0377 16 COG3202 COG3202, ATP/ADP translocase Energy production and conversion 146307837 Common fliM flagellar motor switch protein FliM Pmen_2815 112 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 146308277 Common - hypothetical protein Pmen_3257 5 None None None 146308799 Common - protein of unknown function DUF218 Pmen_3784 51 COG1434 COG1434, Uncharacterized conserved protein Function unknown 146306357 Common - hypothetical protein Pmen_1325 33 COG3257 GlxB, Uncharacterized protein, possibly involved in glyoxylate utilization General function prediction only 146306565 Common - hypothetical protein Pmen_1534 5 None None None 146308995 Common - hypothetical protein Pmen_3981 4 None None None 146305409 Common - ATP-dependent DNA helicase, RecQ family Pmen_0369 237 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 146306574 Common - ABC-type amino acid transport/signal transduction systems periplasmic component/domain-like protein Pmen_1543 7 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146307172 Common - hypothetical protein Pmen_2145 1 None None None 146308582 Common - FAD dependent oxidoreductase Pmen_3567 97 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 146306970 Common - GCN5-related N-acetyltransferase Pmen_1942 81 COG0456 RimI, Acetyltransferases General function prediction only 146305934 Common - Deoxyribonuclease V Pmen_0899 73 COG1515 Nfi, Deoxyinosine 3'endonuclease (endonuclease V) DNA replication, recombination, and repair 146305320 Common - two component transcriptional regulator, LytTR family Pmen_0279 220 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 146307228 Common - transcriptional regulator, LysR family Pmen_2201 102 COG0583 LysR, Transcriptional regulator Transcription 146305304 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Pmen_0263 126 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 146307221 Common - DEAD/H associated domain protein Pmen_2194 135 COG1201 Lhr, Lhr-like helicases General function prediction only 146308595 Common - nitric oxide dioxygenase Pmen_3580 140 COG1017 Hmp, Hemoglobin-like flavoprotein Energy production and conversion 146309604 Common - hypothetical protein Pmen_4590 1 None None None 146308034 Common - hypothetical protein Pmen_3012 8 None None None 146305410 Common - protein of unknown function DUF330 Pmen_0370 29 COG3218 COG3218, ABC-type uncharacterized transport system, auxiliary component General function prediction only 146308826 Common - MORN repeat-containing protein Pmen_3811 34 COG4642 COG4642, Uncharacterized protein conserved in bacteria Function unknown 146306763 Common - integral membrane sensor signal transduction histidine kinase Pmen_1732 215 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146306139 Common - hypothetical protein Pmen_1105 1 None None None 146305640 Common - protein of unknown function UPF0227 Pmen_0605 48 COG3150 COG3150, Predicted esterase General function prediction only 146306651 Common - pseudouridine synthase, RluA family Pmen_1620 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 146306024 Common - 2-isopropylmalate synthase Pmen_0989 211 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 146308913 Common rplN 50S ribosomal protein L14 Pmen_3899 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 146305480 Common - Rubredoxin-type Fe(Cys)4 protein Pmen_0442 103 COG1773 COG1773, Rubredoxin Energy production and conversion 146308791 Common - Sel1 domain protein repeat-containing protein Pmen_3776 89 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 146307202 Common - undecaprenyl pyrophosphate phosphatase Pmen_2175 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 146306007 Common - NADH:flavin oxidoreductase/NADH oxidase Pmen_0972 177 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 146309167 Common - hypothetical protein Pmen_4153 73 COG1872 COG1872, Uncharacterized conserved protein Function unknown 146306660 Common - acyl carrier protein Pmen_1629 211 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 146305233 Common - flagellar motor protein MotA Pmen_0192 78 COG1291 MotA, Flagellar motor component Cell motility and secretion 146305280 Common - OmpA/MotB domain protein Pmen_0239 138 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 146308401 Common - YaeQ family protein Pmen_3382 52 COG4681 COG4681, Uncharacterized protein conserved in bacteria Function unknown 146306015 Common - hypothetical protein Pmen_0980 6 COG3095 MukE, Uncharacterized protein involved in chromosome partitioning Cell division and chromosome partitioning 146309056 Pathogen - hypothetical protein Pmen_4042 1 None None None 146305692 Common - transglutaminase, N-terminal domain protein Pmen_0657 110 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 146309630 Common gidB glucose-inhibited division protein B Pmen_4617 204 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 146305978 Common - hypothetical protein Pmen_0943 13 None None None 146305428 Common - NADH dehydrogenase (quinone) Pmen_0388 164 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 146307027 Common - Na+/H+ antiporter NhaC Pmen_1999 29 COG2056 COG2056, Predicted permease General function prediction only 146306082 Common - putative signal transduction protein with Nacht domain Pmen_1048 36 COG5635 COG5635, Predicted NTPase (NACHT family) Signal transduction mechanisms 146306874 Common - short chain dehydrogenase Pmen_1843 177 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 146305712 Common - aldehyde dehydrogenase Pmen_0677 222 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 146307450 Common - diguanylate cyclase/phosphodiesterase Pmen_2427 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 146309400 Common rph ribonuclease PH Pmen_4386 199 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 146308071 Common frr ribosome recycling factor Pmen_3050 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 146305982 Common - hypoxanthine-guanine phosphoribosyltransferase Pmen_0947 114 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 146306532 Common - regulatory protein, ArsR Pmen_1500 71 COG0640 ArsR, Predicted transcriptional regulators Transcription 146309569 Common - PepSY-associated TM helix domain protein Pmen_4555 37 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 146307528 Common sdhA succinate dehydrogenase flavoprotein subunit Pmen_2505 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 146308170 Common - two component transcriptional regulator, winged helix family Pmen_3150 211 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 146305699 Common - urease accessory protein UreG Pmen_0664 121 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 146305329 Common - hypothetical protein Pmen_0288 17 COG5589 COG5589, Uncharacterized conserved protein Function unknown 146306663 Common - aminodeoxychorismate lyase Pmen_1632 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 146306866 Common - Sua5/YciO/YrdC/YwlC family protein Pmen_1835 231 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 146308648 Common - GntR domain protein Pmen_3633 154 COG2186 FadR, Transcriptional regulators Transcription 146306658 Common - malonyl CoA-acyl carrier protein transacylase Pmen_1627 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 146307213 Common - helix-turn-helix- domain containing protein, AraC type Pmen_2186 92 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 146306830 Common - transcriptional regulator, LysR family Pmen_1799 159 COG0583 LysR, Transcriptional regulator Transcription 146305930 Common - AFG1-family ATPase Pmen_0895 103 COG1485 COG1485, Predicted ATPase General function prediction only 146308186 Common - peptidase U32 Pmen_3166 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 146307272 Common - Rhodanese domain protein Pmen_2246 10 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 146308671 Common - transcriptional regulator, TetR family Pmen_3656 13 COG1309 AcrR, Transcriptional regulator Transcription 146308662 Common - response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) Pmen_3647 206 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 146305518 Common - choline dehydrogenase Pmen_0481 92 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 146308270 Common - hypothetical protein Pmen_3250 18 None None None 146306154 Common - NADH:flavin oxidoreductase/NADH oxidase Pmen_1120 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 146307659 Common - FAD dependent oxidoreductase Pmen_2636 120 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 146309313 Common - putative transcriptional regulator, AsnC family Pmen_4299 159 COG1522 Lrp, Transcriptional regulators Transcription 146309208 Common - Na+/Pi-cotransporter Pmen_4194 76 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 146307540 Common - putative thiol-disulphide oxidoreductase DCC Pmen_2517 29 COG3011 COG3011, Uncharacterized protein conserved in bacteria Function unknown 146307145 Pathogen - hypothetical protein Pmen_2117 1 None None None 146305273 Common - 4-aminobutyrate aminotransferase Pmen_0232 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 146306380 Common - putative PAS/PAC sensor protein Pmen_1348 171 COG3283 TyrR, Transcriptional regulator of aromatic amino acids metabolism Transcription / Amino acid transport and metabolism 146307547 Common - heat shock protein HtpX Pmen_2524 191 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 146308128 Common - diguanylate phosphodiesterase Pmen_3107 162 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 146307907 Common phnH carbon-phosphorus lyase complex subunit Pmen_2885 34 COG3625 PhnH, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 146306517 Common - ATP-dependent helicase HepA Pmen_1485 118 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 146307315 Common - hypothetical protein Pmen_2290 6 COG0439 AccC, Biotin carboxylase Lipid metabolism 146308522 Common hscA chaperone protein HscA Pmen_3507 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 146306227 Common - band 7 protein Pmen_1195 100 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 146308169 Common - integral membrane sensor signal transduction histidine kinase Pmen_3149 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146308811 Common - lytic murein transglycosylase B Pmen_3796 103 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 146308081 Common - aminotransferase, class V Pmen_3060 236 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 146309564 Common - hypothetical protein Pmen_4550 3 None None None 146308424 Common - Lysophospholipase L1 and related esterase-like protein Pmen_3405 21 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 146307348 Common - protein of unknown function DUF877 Pmen_2323 50 COG3517 COG3517, Uncharacterized protein conserved in bacteria Function unknown 146307515 Common - hypothetical protein Pmen_2492 2 None None None 146306375 Common - glycine cleavage system T protein Pmen_1343 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 146307279 Common - hypothetical protein Pmen_2253 8 None None None 146306433 Common - electron transport complex, RnfABCDGE type, D subunit Pmen_1401 76 COG4658 RnfD, Predicted NADH:ubiquinone oxidoreductase, subunit RnfD Energy production and conversion 146306807 Common - hypothetical protein Pmen_1776 74 COG2983 COG2983, Uncharacterized conserved protein Function unknown 146308447 Pathogen - hypothetical protein Pmen_3428 1 None None None 146306551 Common - NADPH-dependent FMN reductase Pmen_1520 66 COG0431 COG0431, Predicted flavoprotein General function prediction only 146307865 Common flgI flagellar basal body P-ring protein Pmen_2843 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 146307718 Common - acyl-CoA synthetase Pmen_2696 191 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 146308320 Common - SMP-30/Gluconolaconase/LRE domain protein Pmen_3300 82 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 146306346 Common - peptidylprolyl isomerase, FKBP-type Pmen_1314 143 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 146307574 Common - type IV pilus assembly PilZ Pmen_2551 5 None None None 146308093 Common - hypothetical protein Pmen_3072 74 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 146308162 Common - 6-phosphogluconolactonase Pmen_3142 103 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 146306697 Common - hypothetical protein Pmen_1666 7 None None None 146306144 Common putA trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase Pmen_1110 220 COG4230 COG4230, Delta 1-pyrroline-5-carboxylate dehydrogenase Energy production and conversion 146308836 Common - beta-lactamase domain protein Pmen_3821 62 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 146306817 Common - Uncharacterized membrane-anchored protein-like protein Pmen_1786 11 COG4714 COG4714, Uncharacterized membrane-anchored protein conserved in bacteria Function unknown 146307247 Common - hypothetical protein Pmen_2220 1 None None None 146308539 Common - RDD domain containing protein Pmen_3524 25 COG1714 COG1714, Predicted membrane protein/domain Function unknown 146306645 Common lpxK tetraacyldisaccharide 4'-kinase Pmen_1614 128 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 146306169 Common - protein of unknown function DUF1329 Pmen_1135 19 None None None 146309492 Common - pyruvate carboxylase subunit B Pmen_4478 216 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 146305084 Pathogen - hypothetical protein Pmen_0043 1 None None None 146307508 Common - Pirin domain protein domain protein Pmen_2485 141 COG1741 COG1741, Pirin-related protein General function prediction only 146306121 Common - protein of unknown function DUF6, transmembrane Pmen_1087 23 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 146305265 Common - protein of unknown function DUF1302 Pmen_0224 18 None None None 146305442 Common - glutathione synthetase Pmen_0402 122 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 146306612 Common fadA 3-ketoacyl-CoA thiolase Pmen_1581 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 146306706 Common - type IV pilus assembly PilZ Pmen_1675 2 COG5581 COG5581, Predicted glycosyltransferase Cell envelope biogenesis, outer membrane 146307501 Common - Methyltransferase type 11 Pmen_2478 2 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 146307268 Common - protein of unknown function DUF156 Pmen_2242 74 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 146308783 Common - iron-hydroxamate transporter permease subunit Pmen_3768 71 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 146305453 Common - adenosylmethionine--8-amino-7-oxononanoate transaminase Pmen_0413 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 146306821 Common - cysteine synthase A Pmen_1790 219 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 146307899 Common - putative transcriptional regulator, AsnC family Pmen_2877 157 COG1522 Lrp, Transcriptional regulators Transcription 146305886 Common - Na+/Ca+ antiporter, CaCA family Pmen_0851 122 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 146308177 Common - protein of unknown function DUF1289 Pmen_3157 5 COG3313 COG3313, Predicted Fe-S protein General function prediction only 146309275 Common - hypothetical protein Pmen_4261 41 COG0582 XerC, Integrase DNA replication, recombination, and repair 146306987 Common - extracellular solute-binding protein, family 3 Pmen_1959 13 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146308439 Pathogen - hypothetical protein Pmen_3420 1 None None None 146308454 Common - protein of unknown function DUF1185 Pmen_3437 23 None None None 146305534 Common - Membrane dipeptidase Pmen_0497 101 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 146305649 Common - FAD dependent oxidoreductase Pmen_0614 4 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 146306627 Common - Na(+)-translocating NADH-quinone reductase subunit B Pmen_1596 76 COG1805 NqrB, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB Energy production and conversion 146305731 Common - Urease accessory protein UreD Pmen_0696 82 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 146306313 Common - exsB protein Pmen_1281 178 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 146308251 Common - TonB-dependent siderophore receptor Pmen_3231 124 COG4772 FecA, Outer membrane receptor for Fe3+-dicitrate Inorganic ion transport and metabolism 146307955 Common - TPR repeat-containing protein Pmen_2933 41 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 146308863 Common - aspartyl protease-like protein Pmen_3849 43 COG3577 COG3577, Predicted aspartyl protease General function prediction only 146306518 Common - hypothetical protein Pmen_1486 1 None None None 146305063 Pathogen - hypothetical protein Pmen_0021 1 None None None 146305190 Common - cytochrome oxidase assembly Pmen_0149 36 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 146305078 Common - IS66 Orf2 family protein Pmen_0037 50 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 146309148 Common - Threonine aldolase Pmen_4134 115 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 146307513 Common - dienelactone hydrolase Pmen_2490 80 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 146306455 Common - OmpA/MotB domain protein Pmen_1423 170 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 146308807 Common - lipoate-protein ligase B Pmen_3792 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 146307413 Common aat leucyl/phenylalanyl-tRNA--protein transferase Pmen_2390 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 146306496 Common - protein of unknown function DUF339 Pmen_1464 43 COG2938 COG2938, Uncharacterized conserved protein Function unknown 146305914 Common - toluene tolerance family protein Pmen_0879 37 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 146306203 Common - outer membrane porin Pmen_1171 11 None None None 146309239 Common - heavy metal translocating P-type ATPase Pmen_4225 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 146309085 Common - nucleoside recognition domain protein Pmen_4071 22 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 146308049 Common - Alcohol dehydrogenase GroES domain protein Pmen_3028 190 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 146308131 Common - transcriptional regulator, TyrR Pmen_3111 169 COG3283 TyrR, Transcriptional regulator of aromatic amino acids metabolism Transcription / Amino acid transport and metabolism 146308351 Common - protein of unknown function DUF195 Pmen_3332 137 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 146306771 Common - hypothetical protein Pmen_1740 8 None None None 146306916 Common - putative phosphohistidine phosphatase, SixA Pmen_1886 13 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 146305131 Common - uncharacterised conserved protein UCP028301 Pmen_0090 50 COG3516 COG3516, Uncharacterized protein conserved in bacteria Function unknown 146308697 Common - ribosomal protein L21 Pmen_3682 211 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 146309249 Common - 2OG-Fe(II) oxygenase Pmen_4235 30 COG3751 EGL-9, Predicted proline hydroxylase Posttranslational modification, protein turnover, chaperones 146309336 Common - alkanesulfonate monooxygenase Pmen_4322 82 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 146305919 Common hisD histidinol dehydrogenase Pmen_0884 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 146307147 Pathogen - hypothetical protein Pmen_2120 1 None None None 146308841 Common - UDP-N-acetylmuramate Pmen_3826 207 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 146308268 Common - Glu/Leu/Phe/Val dehydrogenase, dimerisation region Pmen_3248 109 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 146306752 Common - transcriptional regulator, LysR family Pmen_1721 161 COG0583 LysR, Transcriptional regulator Transcription 146308768 Common - Carbonate dehydratase Pmen_3753 52 COG3338 Cah, Carbonic anhydrase Inorganic ion transport and metabolism 146309358 Common - hypothetical protein Pmen_4344 2 COG5583 COG5583, Uncharacterized small protein Function unknown 146309232 Common - dinucleoside polyphosphate hydrolase Pmen_4218 113 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 146305912 Common - protein of unknown function DUF140 Pmen_0877 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 146305133 Common - GPW/gp25 family protein Pmen_0092 13 COG3518 COG3518, Uncharacterized protein conserved in bacteria Function unknown 146307396 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Pmen_2373 194 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 146305122 Pathogen - hypothetical protein Pmen_0081 1 None None None 146309491 Common - protein of unknown function DUF897 Pmen_4477 31 COG3329 COG3329, Predicted permease General function prediction only 146307585 Common - hypothetical protein Pmen_2562 1 None None None 146305539 Common - thioesterase-like protein Pmen_0502 31 COG0824 FcbC, Predicted thioesterase General function prediction only 146309283 Common - ABC transporter related Pmen_4269 249 COG4598 HisP, ABC-type histidine transport system, ATPase component Amino acid transport and metabolism 146306100 Common - Cyclopropane-fatty-acyl-phospholipid synthase Pmen_1066 128 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 146306756 Common - acetyl-CoA acetyltransferase Pmen_1725 169 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 146307928 Common - hypothetical protein Pmen_2906 1 None None None 146305604 Common - type I site-specific deoxyribonuclease, HsdR family Pmen_0567 133 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 146306175 Common - transcriptional regulator, LysR family Pmen_1141 193 COG0583 LysR, Transcriptional regulator Transcription 146307214 Common - magnesium transporter Pmen_2187 173 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 146306116 Common - peptidase C26 Pmen_1082 122 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 146307355 Common - protein of unknown function DUF1305 Pmen_2330 46 COG3520 COG3520, Uncharacterized protein conserved in bacteria Function unknown 146305929 Common - tryptophanyl-tRNA synthetase Pmen_0894 220 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 146309259 Common - Rhodanese domain protein Pmen_4245 108 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 146305574 Common - ribosomal protein L31 Pmen_0537 204 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 146308379 Common - phosphoenolpyruvate carboxylase Pmen_3360 116 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 146309526 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) Pmen_4512 186 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 146305159 Common - phosphoribosylaminoimidazole carboxylase ATPase subunit Pmen_0118 194 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 146307042 Common - transcriptional regulator, LysR family Pmen_2014 177 COG0583 LysR, Transcriptional regulator Transcription 146306887 Common - beta-lactamase domain protein Pmen_1856 126 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 146307060 Common - Propionyl-CoA carboxylase Pmen_2032 148 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 146305289 Common - transcriptional regulator, XRE family Pmen_0248 120 COG1396 HipB, Predicted transcriptional regulators Transcription 146308516 Common - helix-turn-helix domain protein Pmen_3501 77 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 146309425 Common - hypothetical protein Pmen_4411 10 None None None 146308495 Common - isochorismatase hydrolase Pmen_3479 141 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 146307937 Common - polar amino acid ABC transporter, inner membrane subunit Pmen_2915 172 COG4215 ArtQ, ABC-type arginine transport system, permease component Amino acid transport and metabolism 146308545 Common valS valyl-tRNA synthetase Pmen_3530 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 146307187 Common - fatty acid cistrans isomerase Pmen_2160 15 None None None 146306609 Common - UspA domain protein Pmen_1578 149 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 146306076 Common - hypothetical protein Pmen_1041 1 None None None 146307008 Common pheS phenylalanyl-tRNA synthetase subunit alpha Pmen_1980 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 146308299 Common - hypothetical protein Pmen_3279 6 None None None 146306238 Common - peptidylprolyl isomerase, FKBP-type Pmen_1206 142 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 146307173 Common - uncharacterised conserved protein UCP030820 Pmen_2146 52 COG3749 COG3749, Uncharacterized protein conserved in bacteria Function unknown 146307550 Common - transcriptional regulator, TetR family Pmen_2527 90 COG1309 AcrR, Transcriptional regulator Transcription 146305955 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase Pmen_0920 208 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 146308344 Common - hypothetical protein Pmen_3324 8 None None None 146309392 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase Pmen_4378 181 COG0756 Dut, dUTPase Nucleotide transport and metabolism 146305186 Common - cytochrome c oxidase, subunit III Pmen_0145 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 146307946 Common - general secretion pathway protein F Pmen_2924 140 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 146307237 Common - outer membrane efflux protein Pmen_2210 50 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 146308475 Common - Methenyltetrahydrofolate cyclohydrolase Pmen_3458 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 146306351 Common - Sel1 domain protein repeat-containing protein Pmen_1319 2 None None None 146309002 Common - hypothetical protein Pmen_3988 1 None None None 146307152 Pathogen - hypothetical protein Pmen_2125 1 None None None 146308761 Common - Alcohol dehydrogenase GroES domain protein Pmen_3746 184 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 146308058 Common - acetyl-CoA carboxylase carboxyltransferase subunit alpha Pmen_3037 184 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 146307772 Common - Alkane 1-monooxygenase Pmen_2750 26 None None None 146308336 Common - RDD domain containing protein Pmen_3316 34 COG1714 COG1714, Predicted membrane protein/domain Function unknown 146305821 Common - phosphoenolpyruvate-protein phosphotransferase Pmen_0786 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 146307085 Common - ABC transporter related Pmen_2057 249 COG4172 COG4172, ABC-type uncharacterized transport system, duplicated ATPase component General function prediction only 146308159 Common - methyl-accepting chemotaxis sensory transducer Pmen_3139 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146306240 Common - multidrug efflux protein Pmen_1208 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 146308430 Common - hypothetical protein Pmen_3411 64 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 146309091 Common - phosphate binding protein Pmen_4077 138 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 146305631 Common - LmbE family protein Pmen_0596 4 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 146307159 Common - protein of unknown function DUF81 Pmen_2132 12 COG0730 COG0730, Predicted permeases General function prediction only 146305469 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Pmen_0430 192 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 146307985 Common - heat shock protein DnaJ domain protein Pmen_2963 16 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 146308574 Common - polar amino acid ABC transporter, inner membrane subunit Pmen_3559 168 COG4597 BatB, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 146306979 Common - two component transcriptional regulator, LuxR family Pmen_1951 184 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 146305353 Pathogen - hypothetical protein Pmen_0312 1 None None None 146309067 Common - transcription activator, effector binding Pmen_4053 123 COG3708 COG3708, Uncharacterized protein conserved in bacteria Function unknown 146308968 Common - hypothetical protein Pmen_3954 3 None None None 146306273 Common - GCN5-related N-acetyltransferase Pmen_1241 67 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 146307747 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) Pmen_2725 192 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 146305050 Common - dual specificity protein phosphatase Pmen_0008 21 COG2453 CDC14, Predicted protein-tyrosine phosphatase Signal transduction mechanisms 146308614 Common - protein of unknown function DUF748 Pmen_3599 44 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 146308684 Common - methyl-accepting chemotaxis sensory transducer Pmen_3669 146 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146306852 Common - metallophosphoesterase Pmen_1821 71 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 146307765 Common - Smr protein/MutS2 Pmen_2743 94 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 146309456 Common - twitching motility protein Pmen_4442 157 COG5008 PilU, Tfp pilus assembly protein, ATPase PilU Cell motility and secretion / Intracellular trafficking and secretion 146305996 Common - type IV pilus modification protein PilV Pmen_0961 2 COG4967 PilV, Tfp pilus assembly protein PilV Cell motility and secretion / Intracellular trafficking and secretion 146307890 Common - diaminobutyrate--2-oxoglutarate aminotransferase Pmen_2868 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 146305116 Common - protein of unknown function DUF1458 Pmen_0075 41 COG3360 COG3360, Uncharacterized conserved protein Function unknown 146307884 Common - hypothetical protein Pmen_2862 40 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 146306452 Common - hypothetical protein Pmen_1420 87 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 146307854 Common - flagellar protein FliS Pmen_2832 68 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 146305761 Common - translation initiation factor SUI1 Pmen_0726 51 COG0023 SUI1, Translation initiation factor 1 (eIF-1/SUI1) and related proteins Translation, ribosomal structure and biogenesis 146307133 Common - ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components-like protein Pmen_2105 89 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 146308381 Common - hypothetical protein Pmen_3362 4 None None None 146305380 Common - extracellular solute-binding protein, family 1 Pmen_0340 126 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 146307153 Common - plasmid stabilization system Pmen_2126 9 COG3668 ParE, Plasmid stabilization system protein General function prediction only 146308759 Common - globin Pmen_3744 5 None None None 146308060 Common rnhB ribonuclease HII Pmen_3039 238 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 146305901 Common - Phosphotransferase system, phosphocarrier protein HPr Pmen_0866 141 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 146309197 Common - two component transcriptional regulator, LuxR family Pmen_4183 213 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 146305196 Common - GTPase EngB Pmen_0155 173 COG0218 COG0218, Predicted GTPase General function prediction only 146309025 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Pmen_4011 164 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 146308261 Common - YebG family protein Pmen_3241 11 COG3141 COG3141, Uncharacterized protein conserved in bacteria Function unknown 146306400 Common - transcriptional regulator, LysR family Pmen_1368 187 COG0583 LysR, Transcriptional regulator Transcription 146305868 Common - DJ-1 family protein Pmen_0833 104 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 146306634 Common - soluble pyridine nucleotide transhydrogenase Pmen_1603 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 146307374 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pmen_2349 46 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 146309290 Common - hypothetical protein Pmen_4276 7 COG3274 COG3274, Uncharacterized protein conserved in bacteria Function unknown 146307322 Common - Rho termination factor domain protein Pmen_2297 23 COG1158 Rho, Transcription termination factor Transcription 146306527 Common - acyl-CoA synthetase Pmen_1495 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 146305623 Common - Carbamoyltransferase Pmen_0586 52 COG2192 COG2192, Predicted carbamoyl transferase, NodU family Posttranslational modification, protein turnover, chaperones 146305386 Common - extracellular solute-binding protein, family 1 Pmen_0346 133 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 146307503 Common - diacylglycerol kinase Pmen_2480 60 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 146305763 Common - membrane protein-like protein Pmen_0728 19 COG3556 COG3556, Predicted membrane protein Function unknown 146307235 Common - transcriptional regulator, CopG family Pmen_2208 12 COG3905 COG3905, Predicted transcriptional regulator Transcription 146308199 Common - NUDIX hydrolase Pmen_3179 13 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 146305213 Common - response regulator receiver sensor signal transduction histidine kinase Pmen_0172 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146308209 Common - glucose sorbosone dehydrogenase Pmen_3189 119 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 146306307 Common - Biopolymer transport protein ExbD/TolR Pmen_1275 131 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 146305285 Common - putative transcriptional regulator, AsnC family Pmen_0244 164 COG1522 Lrp, Transcriptional regulators Transcription 146306909 Common - competence protein ComEA helix-hairpin-helix repeat protein Pmen_1879 101 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 146306320 Common - membrane protein involved in aromatic hydrocarbon degradation Pmen_1288 74 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 146306182 Common - two component transcriptional regulator, winged helix family Pmen_1148 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 146307708 Common - extracellular solute-binding protein, family 3 Pmen_2686 7 COG0583 LysR, Transcriptional regulator Transcription 146308476 Common - Flavin-containing monooxygenase Pmen_3459 62 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 146307284 Common - hypothetical protein Pmen_2258 9 COG3729 GsiB, General stress protein General function prediction only 146307625 Common - cytochrome c oxidase, cbb3-type, subunit III Pmen_2602 85 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 146306913 Common - major facilitator superfamily MFS_1 Pmen_1883 76 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 146305586 Common - Sporulation domain protein Pmen_0549 22 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 146307895 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Pmen_2873 109 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 146306711 Common - efflux transporter, RND family, MFP subunit Pmen_1680 167 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 146308192 Common - diguanylate cyclase Pmen_3172 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 146308733 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Pmen_3718 16 COG0546 Gph, Predicted phosphatases General function prediction only 146307589 Common - periplasmic binding protein/LacI transcriptional regulator Pmen_2566 125 COG1609 PurR, Transcriptional regulators Transcription 146307571 Common - 5'-nucleotidase Pmen_2548 31 None None None 146306723 Common - BolA family protein Pmen_1692 102 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 146307920 Common - Ketosteroid isomerase-related protein-like protein Pmen_2898 15 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 146306271 Common - VacJ family lipoprotein Pmen_1239 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 146307604 Common - response regulator receiver and ANTAR domain protein Pmen_2581 99 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 146306048 Common - Paraquat-inducible protein A Pmen_1013 54 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 146307909 Common - transcriptional regulator, GntR family Pmen_2887 109 COG2188 PhnF, Transcriptional regulators Transcription 146307693 Common - putative transcriptional regulator, GntR family Pmen_2671 221 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 146308483 Common - glutamate synthase, alpha subunit domain protein Pmen_3466 59 COG0070 GltB, Glutamate synthase domain 3 Amino acid transport and metabolism 146309102 Common - biotin synthase Pmen_4088 183 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 146308151 Common malF maltose transporter membrane protein Pmen_3131 139 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 146309421 Common - PAS/PAC sensor signal transduction histidine kinase Pmen_4407 218 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 146308851 Common - Extracellular ligand-binding receptor Pmen_3837 147 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 146308970 Pathogen - hypothetical protein Pmen_3956 1 None None None 146308677 Common - acetyl-CoA acetyltransferase Pmen_3662 186 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 146307398 Common - two component transcriptional regulator, LuxR family Pmen_2375 211 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 146308133 Common phhB pterin-4-alpha-carbinolamine dehydratase Pmen_3113 90 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 146306842 Common - yecA family protein Pmen_1811 14 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 146305490 Common ligB NAD-dependent DNA ligase LigB Pmen_0453 218 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 146305925 Common - sulfate adenylyltransferase subunit 2 Pmen_0890 143 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 146305111 Common trpA tryptophan synthase subunit alpha Pmen_0070 214 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 146309010 Common - phage integrase family protein Pmen_3996 101 COG0582 XerC, Integrase DNA replication, recombination, and repair 146309127 Common - hypothetical protein Pmen_4113 6 COG4339 COG4339, Uncharacterized protein conserved in bacteria Function unknown 146305819 Common - AsmA family protein Pmen_0784 47 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 146308622 Common rbfA ribosome-binding factor A Pmen_3607 172 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 146306098 Common - hypothetical protein Pmen_1064 12 None None None 146307852 Common - hypothetical protein Pmen_2830 1 None None None 146307138 Common - phage integrase family protein Pmen_2110 188 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 146307198 Common - ATPase/kinase involved in NAD metabolism-like protein Pmen_2171 12 COG3172 NadR, Predicted ATPase/kinase involved in NAD metabolism Coenzyme metabolism 146306557 Common - periplasmic protein-like protein Pmen_1526 8 COG3904 COG3904, Predicted periplasmic protein Function unknown 146306317 Common - D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Pmen_1285 65 COG3957 COG3957, Phosphoketolase Carbohydrate transport and metabolism 146306583 Pathogen - hypothetical protein Pmen_1552 1 None None None 146306902 Common - polysaccharide biosynthesis protein CapD Pmen_1872 204 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 146308088 Common - rRNA (guanine-N(1)-)-methyltransferase Pmen_3067 58 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 146307910 Common - phosphonate ABC transporter, inner membrane subunit Pmen_2888 93 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 146308525 Common - scaffold protein Pmen_3510 150 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 146307811 Common - heme exporter protein CcmC Pmen_2789 131 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 146307733 Common - amidophosphoribosyltransferase Pmen_2711 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 146308838 Common - protein of unknown function DUF1375 Pmen_3823 1 COG5645 COG5645, Predicted periplasmic lipoprotein General function prediction only 146309389 Common - 4-phytase Pmen_4375 206 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 146305118 Pathogen - hypothetical protein Pmen_0077 1 None None None 146307324 Pathogen - hypothetical protein Pmen_2299 1 COG5637 COG5637, Predicted integral membrane protein Function unknown 146309523 Common - putative FecR Pmen_4509 48 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 146306205 Common - heavy metal sensor signal transduction histidine kinase Pmen_1173 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146306444 Common - isochorismatase hydrolase Pmen_1412 82 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 146308922 Common rplD 50S ribosomal protein L4 Pmen_3908 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 146305830 Common - integral membrane sensor signal transduction histidine kinase Pmen_0795 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146305789 Common - protein of unknown function DUF465 Pmen_0754 24 COG2841 COG2841, Uncharacterized protein conserved in bacteria Function unknown 146307971 Common - TRAP transporter solute receptor, TAXI family Pmen_2949 89 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 146309560 Common - transcriptional regulator, LysR family Pmen_4546 191 COG0583 LysR, Transcriptional regulator Transcription 146307122 Common - molybdopterin oxidoreductase Pmen_2094 189 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 146308742 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pmen_3727 14 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 146307978 Common - Glutathione synthase Pmen_2956 78 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 146305785 Common - Zn-dependent protease-like protein Pmen_0750 41 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 146308701 Common fxsA FxsA Pmen_3686 41 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 146309539 Common - Glutamate--putrescine ligase Pmen_4525 228 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 146306524 Common - secretion protein HlyD family protein Pmen_1492 129 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 146306473 Common - putative monovalent cation/H+ antiporter subunit A Pmen_1441 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 146305437 Common pyrB aspartate carbamoyltransferase catalytic subunit Pmen_0397 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 146308149 Common - transcriptional regulator MalT Pmen_3129 84 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 146306963 Common dnaE2 error-prone DNA polymerase Pmen_1934 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 146308561 Common - inner membrane protein YjeH Pmen_3546 57 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 146309565 Common - PAAR repeat-containing protein Pmen_4551 29 COG4104 COG4104, Uncharacterized conserved protein Function unknown 146309599 Common - Magnesium chelatase Pmen_4585 68 COG1239 ChlI, Mg-chelatase subunit ChlI Coenzyme metabolism 146306043 Common - DNA-binding transcriptional regulator IlvY Pmen_1008 187 COG0583 LysR, Transcriptional regulator Transcription 146306198 Common - hypothetical protein Pmen_1165 1 None None None 146305102 Common aroE shikimate 5-dehydrogenase Pmen_0061 219 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 146307888 Common - iron-hydroxamate transporter permease subunit Pmen_2866 189 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 146308369 Common - acriflavin resistance protein Pmen_3350 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 146306879 Common - DNA gyrase subunit A Pmen_1848 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 146305359 Common - diguanylate cyclase with PAS/PAC sensor Pmen_0318 177 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 146305857 Common - hypothetical protein Pmen_0822 1 None None None 146306714 Common - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase Pmen_1683 141 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 146306958 Common - response regulator receiver protein Pmen_1929 226 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 146305226 Common - peptidase M23B Pmen_0185 180 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 146309576 Common - integral membrane sensor signal transduction histidine kinase Pmen_4562 216 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 146307567 Common - phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein Pmen_2544 19 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 146307679 Common - outer membrane efflux protein Pmen_2657 42 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 146307633 Common - heavy metal translocating P-type ATPase Pmen_2610 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 146309054 Common - two component transcriptional regulator, LuxR family Pmen_4040 172 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 146305202 Common - IS66 Orf2 family protein Pmen_0161 50 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 146308730 Common - efflux transporter, RND family, MFP subunit Pmen_3715 146 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 146305796 Pathogen - hypothetical protein Pmen_0761 1 None None None 146306192 Common - hypothetical protein Pmen_1158 1 None None None 146307670 Common - hypothetical protein Pmen_2648 1 None None None 146307067 Common - putative transcriptional regulator, AsnC family Pmen_2039 116 COG1522 Lrp, Transcriptional regulators Transcription 146305503 Common - protein of unknown function DUF45 Pmen_0466 41 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 146305856 Common - heavy metal translocating P-type ATPase Pmen_0821 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 146306413 Common - uracil-DNA glycosylase Pmen_1381 130 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 146305812 Common - Fimbrial protein pilin Pmen_0777 8 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 146306399 Pathogen - hypothetical protein Pmen_1367 1 None None None 146306700 Common - hypothetical protein Pmen_1669 4 None None None 146309110 Common - malate synthase G Pmen_4096 67 COG2225 AceB, Malate synthase Energy production and conversion 146306329 Common - hypothetical protein Pmen_1297 1 None None None 146308749 Common - extracellular solute-binding protein, family 3 Pmen_3734 76 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146305780 Common - acetyl-CoA acetyltransferase Pmen_0745 171 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 146306944 Common - hypothetical protein Pmen_1915 3 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 146307640 Common - Ion transport protein Pmen_2617 26 None None None 146307129 Common - sulfatase Pmen_2101 68 COG3083 COG3083, Predicted hydrolase of alkaline phosphatase superfamily General function prediction only 146306191 Common - transcriptional regulator, LysR family Pmen_1157 112 COG0583 LysR, Transcriptional regulator Transcription 146308246 Common - transcriptional regulator, LysR family Pmen_3226 145 COG0583 LysR, Transcriptional regulator Transcription 146307613 Common - 3-hydroxyacyl-CoA dehydrogenase, NAD-binding Pmen_2590 157 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 146308279 Pathogen - hypothetical protein Pmen_3259 1 None None None 146308588 Common - H(+)-transporting two-sector ATPase Pmen_3573 93 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 146307663 Common ftrA transcriptional activator FtrA Pmen_2641 128 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 146309479 Common - Bile acid:sodium symporter Pmen_4465 55 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 146307959 Common - protein of unknown function DUF1329 Pmen_2937 19 None None None 146306087 Common - peptidyl-tRNA hydrolase Pmen_1053 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 146306891 Common - DegT/DnrJ/EryC1/StrS aminotransferase Pmen_1860 209 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 146308011 Common - arsenate reductase Pmen_2989 116 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 146305893 Common - Rod shape-determining protein MreD Pmen_0858 63 COG2891 MreD, Cell shape-determining protein Cell envelope biogenesis, outer membrane 146306939 Common - transcriptional regulator, MarR family Pmen_1910 93 COG1846 MarR, Transcriptional regulators Transcription 146307035 Common - ABC transporter related Pmen_2007 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 146309095 Common - acyl-CoA dehydrogenase domain protein Pmen_4081 148 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 146308541 Common - permease YjgP/YjgQ family protein Pmen_3526 86 COG0795 COG0795, Predicted permeases General function prediction only 146307776 Common - guanine deaminase Pmen_2754 171 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 146306260 Common - hypothetical protein Pmen_1228 14 None None None 146306394 Common - 2OG-Fe(II) oxygenase Pmen_1362 54 COG3491 PcbC, Isopenicillin N synthase and related dioxygenases General function prediction only 146309240 Common - putative transcriptional regulator, MerR family Pmen_4226 143 COG0789 SoxR, Predicted transcriptional regulators Transcription 146306630 Common - Na(+)-translocating NADH-quinone reductase subunit E Pmen_1599 76 COG2209 NqrE, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE Energy production and conversion 146307363 Common - hypothetical protein Pmen_2338 5 None None None 146307386 Common - Acyl-CoA dehydrogenase, type 2, C-terminal domain Pmen_2361 87 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 146306292 Common - outer membrane porin Pmen_1260 10 None None None 146308428 Common - NUDIX hydrolase Pmen_3409 130 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 146308117 Common - hypothetical protein Pmen_3096 117 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 146306409 Common - methylmalonate-semialdehyde dehydrogenase Pmen_1377 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 146308468 Common - flavin reductase domain protein, FMN-binding Pmen_3451 115 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 146307894 Common - cyclic peptide transporter Pmen_2872 242 COG4615 PvdE, ABC-type siderophore export system, fused ATPase and permease components Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism 146305687 Common - hypothetical protein Pmen_0652 73 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 146308463 Common - bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein Pmen_3446 229 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 146309263 Common - extracellular solute-binding protein, family 3 Pmen_4249 24 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146307539 Common - DoxX family protein Pmen_2516 3 None None None 146306136 Common - thioesterase superfamily protein Pmen_1102 63 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 146306870 Common - putative transcriptional regulator Pmen_1839 143 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 146308280 Common - UspA domain protein Pmen_3260 59 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 146307461 Common - Integral membrane protein TerC Pmen_2438 95 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 146308445 Common - DEAD/DEAH box helicase domain protein Pmen_3426 132 COG1201 Lhr, Lhr-like helicases General function prediction only 146306881 Common - chorismate mutase Pmen_1850 213 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 146305160 Common - phosphoribosylaminoimidazole carboxylase, catalytic subunit Pmen_0119 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 146308066 Common - surface antigen (D15) Pmen_3045 160 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 146308607 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase Pmen_3592 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 146305557 Common hisI phosphoribosyl-AMP cyclohydrolase Pmen_0520 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 146307790 Common - protein of unknown function DUF336 Pmen_2768 34 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 146306034 Common - TfoX, C-terminal domain protein Pmen_0999 3 COG3070 TfoX, Regulator of competence-specific genes Transcription 146307256 Common - hypothetical protein Pmen_2230 1 None None None 146308858 Common - 1-deoxy-D-xylulose-5-phosphate synthase Pmen_3844 226 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 146306734 Common - Antibiotic biosynthesis monooxygenase Pmen_1703 37 COG1359 COG1359, Uncharacterized conserved protein Function unknown 146306769 Common - transcriptional antiterminator, Rof Pmen_1738 14 COG4568 Rof, Transcriptional antiterminator Transcription 146308110 Common - protein of unknown function DUF6, transmembrane Pmen_3089 40 None None None 146306858 Common - protein of unknown function UPF0153 Pmen_1827 18 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 146308289 Common - AFG1-family ATPase Pmen_3269 102 COG1485 COG1485, Predicted ATPase General function prediction only 146308565 Common - protein of unknown function DUF344 Pmen_3550 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 146309069 Pathogen - hypothetical protein Pmen_4055 1 None None None 146305986 Common - integral membrane protein MviN Pmen_0951 194 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 146306484 Common - membrane protein-like protein Pmen_1452 9 COG3650 COG3650, Predicted membrane protein Function unknown 146306547 Common - hypothetical protein Pmen_1516 8 None None None 146306058 Common - membrane bound O-acyl transferase, MBOAT family protein Pmen_1023 86 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 146308553 Common - SMC domain protein Pmen_3538 97 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 146308221 Common - helix-turn-helix- domain containing protein, AraC type Pmen_3201 120 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 146305680 Common rpsF 30S ribosomal protein S6 Pmen_0645 195 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 146309634 Common - protein of unknown function DUF37 Pmen_4621 173 COG0759 COG0759, Uncharacterized conserved protein Function unknown 146307448 Common - Trans-aconitate 2-methyltransferase Pmen_2425 79 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 146305848 Pathogen - hypothetical protein Pmen_0813 1 None None None 146307079 Common clpX ATP-dependent protease ATP-binding subunit Pmen_2051 229 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 146307914 Common - sodium ion-translocating decarboxylase, beta subunit Pmen_2892 56 COG1883 OadB, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit Energy production and conversion 146308828 Common - hypothetical protein Pmen_3813 1 None None None 146305849 Pathogen - hypothetical protein Pmen_0814 1 None None None 146309347 Common - aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein Pmen_4333 82 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 146309405 Common - putative endoribonuclease L-PSP Pmen_4391 190 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 146305742 Common - phosphoribosylamine--glycine ligase Pmen_0707 232 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 146305827 Common prfC peptide chain release factor 3 Pmen_0792 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 146307258 Common - Uncharacterized copper-binding protein-like protein Pmen_2232 27 COG4454 COG4454, Uncharacterized copper-binding protein Inorganic ion transport and metabolism 146305299 Common - protein of unknown function DUF526 Pmen_0258 2 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 146305166 Common - transcriptional regulator, AraC family Pmen_0125 161 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 146305474 Common - IS66 Orf2 family protein Pmen_0435 50 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 146305776 Common - hypothetical protein Pmen_0741 43 COG1694 MazG, Predicted pyrophosphatase General function prediction only 146308896 Common - Na+/H+ antiporter NhaC Pmen_3882 61 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 146308100 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Pmen_3079 62 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 146309471 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Pmen_4457 165 COG0546 Gph, Predicted phosphatases General function prediction only 146308757 Common - putative transcriptional regulator, AsnC family Pmen_3742 150 COG1522 Lrp, Transcriptional regulators Transcription 146307476 Common - hypothetical protein Pmen_2453 1 None None None 146305069 Pathogen - hypothetical protein Pmen_0027 2 None None None 146306894 Common - polysaccharide biosynthesis protein Pmen_1863 36 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 146309596 Common - GCN5-related N-acetyltransferase Pmen_4582 29 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 146306853 Common - glycosyl transferase, group 1 Pmen_1822 183 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 146307357 Common - Rhs element Vgr protein Pmen_2332 76 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 146307650 Common - protein of unknown function DUF480 Pmen_2627 41 COG3132 COG3132, Uncharacterized protein conserved in bacteria Function unknown 146307036 Common - polar amino acid ABC transporter, inner membrane subunit Pmen_2008 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 146307598 Common - tRNA--hydroxylase Pmen_2575 40 COG4445 MiaE, Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 146307296 Common - hypothetical protein Pmen_2271 2 None None None 146307756 Common - transcriptional regulator, LysR family Pmen_2734 152 COG0583 LysR, Transcriptional regulator Transcription 146307117 Common - hypothetical protein Pmen_2089 1 None None None 146308557 Common - exonuclease subunit SbcD Pmen_3542 107 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 146308940 Common - biotin--protein ligase Pmen_3926 222 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 146306921 Common - Alpha/beta hydrolase fold-3 domain protein Pmen_1891 120 COG0657 Aes, Esterase/lipase Lipid metabolism 146309483 Common - binding-protein-dependent transport systems inner membrane component Pmen_4469 149 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 146308385 Common - protein of unknown function DUF124 Pmen_3366 62 COG2013 COG2013, Uncharacterized conserved protein Function unknown 146308026 Common - deoxyguanosinetriphosphate triphosphohydrolase-like protein Pmen_3004 159 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 146305645 Common - type I secretion outer membrane protein, TolC family Pmen_0610 138 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 146308909 Common rpsH 30S ribosomal protein S8 Pmen_3895 234 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 146306837 Common - Hemolysin-type calcium-binding region Pmen_1806 81 COG4245 TerY, Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain General function prediction only 146305617 Common - lipopolysaccharide heptosyltransferase I Pmen_0580 96 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 146307016 Common - transposase IS66 Pmen_1988 67 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 146307115 Common - ribonuclease activity regulator protein RraA Pmen_2087 106 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 146306467 Common - OmpA/MotB domain protein Pmen_1435 124 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 146305550 Common - proline iminopeptidase Pmen_0513 129 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 146305957 Common murG N-acetylglucosaminyl transferase Pmen_0922 208 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 146309184 Common mtgA monofunctional biosynthetic peptidoglycan transglycosylase Pmen_4170 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 146307311 Common - integral membrane protein-like protein Pmen_2286 51 COG0392 COG0392, Predicted integral membrane protein Function unknown 146305257 Common flgL flagellar hook-associated protein FlgL Pmen_0216 95 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 146307101 Common - hypothetical protein Pmen_2073 7 None None None 146307615 Common - Rhodanese domain protein Pmen_2592 75 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 146307861 Common - Methyltransferase type 12 Pmen_2839 8 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 146309279 Pathogen - hypothetical protein Pmen_4265 1 None None None 146307557 Common - membrane protein involved in aromatic hydrocarbon degradation Pmen_2534 48 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 146306065 Common - hypothetical protein Pmen_1030 5 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 146307091 Common - Lytic transglycosylase, catalytic Pmen_2063 160 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 146305290 Common - Cytochrome c5-like protein Pmen_0249 43 COG3245 CycB, Cytochrome c5 Energy production and conversion 146305758 Common - response regulator receiver modulated diguanylate cyclase Pmen_0723 221 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 146307464 Common - DoxX family protein Pmen_2441 41 COG2259 COG2259, Predicted membrane protein Function unknown 146306093 Common hemA glutamyl-tRNA reductase Pmen_1059 182 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 146308443 Common - hypothetical protein Pmen_3424 15 None None None 146308793 Pathogen - hypothetical protein Pmen_3778 1 None None None 146307793 Common - 2-hydroxy-3-oxopropionate reductase Pmen_2771 170 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 146309073 Common - protein of unknown function DUF839 Pmen_4059 66 COG3211 PhoX, Predicted phosphatase General function prediction only 146307873 Common - Protein-glutamate O-methyltransferase Pmen_2851 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 146306259 Common - diguanylate cyclase/phosphodiesterase Pmen_1227 171 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 146309238 Common - hypothetical protein Pmen_4224 18 None None None 146308861 Common - hypothetical protein Pmen_3847 1 None None None 146305378 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Pmen_0338 187 COG0388 COG0388, Predicted amidohydrolase General function prediction only 146308372 Common - protein of unknown function DUF548 Pmen_3353 51 None None None 146306457 Common - hypothetical protein Pmen_1425 1 None None None 146305327 Common - peptidylprolyl isomerase, FKBP-type Pmen_0286 122 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 146307580 Common - hypothetical protein Pmen_2557 1 None None None 146307591 Common - TRAP dicarboxylate transporter, DctM subunit Pmen_2568 122 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 146308879 Common - protein of unknown function DUF214 Pmen_3865 37 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 146307724 Common - OmpA/MotB domain protein Pmen_2702 171 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 146308272 Common - secretion protein HlyD family protein Pmen_3252 99 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 146307055 Common - ABC-type amino acid transport/signal transduction systems periplasmic component/domain-like protein Pmen_2027 14 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146308107 Pathogen - hypothetical protein Pmen_3086 1 None None None 146309628 Common - parB-like partition protein Pmen_4615 185 COG1475 Spo0J, Predicted transcriptional regulators Transcription 146305173 Common - GCN5-related N-acetyltransferase Pmen_0132 68 COG0456 RimI, Acetyltransferases General function prediction only 146306832 Common - DTW domain containing protein Pmen_1801 38 COG3148 COG3148, Uncharacterized conserved protein Function unknown 146309227 Common thyA thymidylate synthase Pmen_4213 140 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 146309509 Common - periplasmic solute binding protein Pmen_4495 76 COG4531 ZnuA, ABC-type Zn2+ transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 146306776 Common - molybdenum cofactor synthesis domain Pmen_1745 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 146308001 Common - periplasmic nitrate reductase NapE Pmen_2979 3 COG4459 NapE, Periplasmic nitrate reductase system, NapE component Energy production and conversion 146305446 Common - methyl-accepting chemotaxis sensory transducer Pmen_0406 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146308500 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein Pmen_3485 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 146309409 Common - NAD-dependent epimerase/dehydratase Pmen_4395 97 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 146308184 Common - proteinase inhibitor I11, ecotin Pmen_3164 23 COG4574 Eco, Serine protease inhibitor ecotin General function prediction only 146309220 Common - phosphodiesterase, MJ0936 family Pmen_4206 70 COG0622 COG0622, Predicted phosphoesterase General function prediction only 146306242 Common - methyl-accepting chemotaxis sensory transducer Pmen_1210 145 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146305333 Common - iron permease FTR1 Pmen_0292 53 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 146305625 Common - hypothetical protein Pmen_0588 7 None None None 146307332 Common - UTP-glucose-1-phosphate uridylyltransferase GalU Pmen_2307 232 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 146306229 Common - hypothetical protein Pmen_1197 21 None None None 146306212 Common - putative transcriptional regulator, XRE family Pmen_1180 59 COG3655 COG3655, Predicted transcriptional regulator Transcription 146308501 Common - inositol-5-monophosphate dehydrogenase Pmen_3486 240 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 146308943 Common anmK anhydro-N-acetylmuramic acid kinase Pmen_3929 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 146309311 Common - TRAP dicarboxylate transporter, DctM subunit Pmen_4297 133 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 146306847 Common - Patatin Pmen_1816 147 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 146308021 Common - Rh family protein/ammonium transporter Pmen_2999 203 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 146309342 Common - hypothetical protein Pmen_4328 7 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 146306813 Common - hypothetical protein Pmen_1782 2 None None None 146309521 Common - Haem oxygenase Pmen_4507 9 COG3230 HemO, Heme oxygenase Inorganic ion transport and metabolism 146306515 Common - YhhN family protein Pmen_1483 14 COG3714 COG3714, Predicted membrane protein Function unknown 146307209 Common - filamentation induced by cAMP protein Fic Pmen_2182 14 COG3177 COG3177, Uncharacterized conserved protein Function unknown 146306643 Common - MotA/TolQ/ExbB proton channel Pmen_1612 94 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 146307083 Common - phospholipase D/Transphosphatidylase Pmen_2055 129 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 146307939 Common - General secretion pathway M protein Pmen_2917 2 COG3149 PulM, Type II secretory pathway, component PulM Intracellular trafficking and secretion 146308459 Common - Carboxymuconolactone decarboxylase Pmen_3442 83 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 146307668 Common - hypothetical protein Pmen_2646 175 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 146308540 Common - permease YjgP/YjgQ family protein Pmen_3525 107 COG0795 COG0795, Predicted permeases General function prediction only 146305271 Common - hypothetical protein Pmen_0230 1 COG5645 COG5645, Predicted periplasmic lipoprotein General function prediction only 146307919 Common - hypothetical protein Pmen_2897 9 None None None 146309364 Common - transcriptional regulator, XRE family Pmen_4350 31 COG1396 HipB, Predicted transcriptional regulators Transcription 146305888 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B Pmen_0853 213 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 146305365 Common - hypothetical protein Pmen_0324 38 COG3079 COG3079, Uncharacterized protein conserved in bacteria Function unknown 146306219 Common - DEAD/DEAH box helicase domain protein Pmen_1187 111 COG1204 COG1204, Superfamily II helicase General function prediction only 146306338 Common - DEAD/DEAH box helicase domain protein Pmen_1306 241 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 146308708 Common - N-hydroxyarylamine O-acetyltransferase Pmen_3693 45 COG2162 NhoA, Arylamine N-acetyltransferase Secondary metabolites biosynthesis, transport, and catabolism 146307943 Common - general secretion pathway protein I Pmen_2921 14 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 146309550 Common - cobalamin synthesis protein, P47K Pmen_4536 129 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 146308321 Common - TRAP dicarboxylate transporter, DctP subunit Pmen_3301 119 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 146305594 Common - Citrate transporter Pmen_0557 130 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 146306152 Common - hypothetical protein Pmen_1118 2 None None None 146306782 Common - cobyrinic acid a,c-diamide synthase Pmen_1751 137 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 146306780 Common - hypothetical protein Pmen_1749 13 None None None 146306999 Common - iron-containing alcohol dehydrogenase Pmen_1971 175 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 146308951 Common - protein of unknown function DUF805 Pmen_3937 40 COG3152 COG3152, Predicted membrane protein Function unknown 146308163 Common - glucose-6-phosphate 1-dehydrogenase Pmen_3143 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 146305170 Common - sodium:dicarboxylate symporter Pmen_0129 164 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 146306819 Common - ATPase associated with various cellular activities, AAA_5 Pmen_1788 98 COG0714 COG0714, MoxR-like ATPases General function prediction only 146309430 Common - flagellar motor switch protein FliG Pmen_4416 120 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 146306754 Common - acyl-CoA dehydrogenase domain protein Pmen_1723 162 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 146309318 Common - protein of unknown function DUF107 Pmen_4304 48 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 146305874 Common - binding-protein-dependent transport systems inner membrane component Pmen_0839 218 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 146305544 Common - diguanylate cyclase with PAS/PAC sensor Pmen_0507 183 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 146305444 Common - response regulator receiver protein Pmen_0404 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 146307306 Common - hypothetical protein Pmen_2281 2 None None None 146306377 Common - glycine dehydrogenase Pmen_1345 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 146306430 Common - endonuclease III Pmen_1398 240 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 146309328 Common - response regulator receiver protein Pmen_4314 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 146306672 Common - hypothetical protein Pmen_1641 1 None None None 146307517 Common - thioesterase superfamily protein Pmen_2494 30 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 146305530 Common - electron transfer flavoprotein, alpha subunit Pmen_0493 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 146309268 Common - hypothetical protein Pmen_4254 4 COG5460 COG5460, Uncharacterized conserved protein Function unknown 146307164 Common - protein of unknown function DUF1006 Pmen_2137 60 COG3214 COG3214, Uncharacterized protein conserved in bacteria Function unknown 146309308 Common - two component, sigma54 specific, transcriptional regulator, Fis family Pmen_4294 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 146305267 Common - Glutathione S-transferase, N-terminal domain Pmen_0226 67 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 146306230 Common - transcriptional regulator, TraR/DksA family Pmen_1198 30 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 146306055 Common - mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase Pmen_1020 164 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 146308239 Common - putative transcriptional regulator, MerR family Pmen_3219 132 COG0789 SoxR, Predicted transcriptional regulators Transcription 146305047 Common - phosphatidate cytidylyltransferase Pmen_0005 215 COG4589 COG4589, Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase General function prediction only 146306159 Common - phospholipid/glycerol acyltransferase Pmen_1125 103 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 146305549 Common - hypothetical protein Pmen_0512 2 None None None 146307681 Pathogen - hypothetical protein Pmen_2659 1 None None None 146306348 Common - hypothetical protein Pmen_1316 4 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146308452 Common - hypothetical protein Pmen_3434 16 None None None 146309334 Common ssuB aliphatic sulfonates transport ATP-binding subunit Pmen_4320 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 146307488 Common - phosphohistidine phosphatase, SixA Pmen_2465 74 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 146307754 Common - transcriptional regulator, TetR family Pmen_2732 51 COG1309 AcrR, Transcriptional regulator Transcription 146306350 Common - hypothetical protein Pmen_1318 2 None None None 146307266 Common - hypothetical protein Pmen_2240 34 None None None 146307802 Common - Ion transport protein Pmen_2780 96 COG1226 Kch, Kef-type K+ transport systems, predicted NAD-binding component Inorganic ion transport and metabolism 146306629 Common - Na(+)-translocating NADH-quinone reductase subunit D Pmen_1598 76 COG1347 NqrD, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD Energy production and conversion 146309143 Common - sarcosine oxidase, alpha subunit family Pmen_4129 180 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 146306823 Common aceK bifunctional isocitrate dehydrogenase kinase/phosphatase protein Pmen_1792 29 COG4579 COG4579, Isocitrate dehydrogenase kinase/phosphatase Signal transduction mechanisms 146308937 Common - elongation factor Tu Pmen_3923 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 146309023 Common - aminoglycoside phosphotransferase Pmen_4009 90 COG3178 COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases General function prediction only 146305407 Common hslO Hsp33-like chaperonin Pmen_0367 93 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 146306167 Common - Superfamily I DNA and RNA helicase and helicase subunits-like protein Pmen_1133 99 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 146305952 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase Pmen_0917 212 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 146306812 Common - Oligopeptidase B Pmen_1781 101 COG1770 PtrB, Protease II Amino acid transport and metabolism 146307435 Common - NADH dehydrogenase subunit A Pmen_2412 162 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 146306699 Common algL poly(beta-D-mannuronate) lyase Pmen_1668 3 None None None 146308660 Common - phosphate acetyltransferase Pmen_3645 176 COG0280 Pta, Phosphotransacetylase Energy production and conversion 146306708 Common - mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase Pmen_1677 164 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 146307576 Common - acetyltransferase-like protein Pmen_2553 22 COG2388 COG2388, Predicted acetyltransferase General function prediction only 146306142 Common - arginine deiminase Pmen_1108 54 COG2235 ArcA, Arginine deiminase Amino acid transport and metabolism 146306820 Common - hypothetical protein Pmen_1789 8 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 146306558 Common - major facilitator superfamily MFS_1 Pmen_1527 130 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 146308597 Common - NnrS family protein Pmen_3582 53 COG3213 NnrS, Uncharacterized protein involved in response to NO Inorganic ion transport and metabolism 146309261 Common - peptidase M23B Pmen_4247 188 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 146306535 Common - hypothetical protein Pmen_1503 1 None None None 146308634 Common greA transcription elongation factor GreA Pmen_3619 204 COG0782 GreA, Transcription elongation factor Transcription 146307184 Common - hypothetical protein Pmen_2157 4 None None None 146307552 Common - Alcohol dehydrogenase GroES domain protein Pmen_2529 112 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 146306355 Common - Peroxiredoxin Pmen_1323 212 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 146307521 Common - branched-chain amino acid transport system II carrier protein Pmen_2498 50 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 146307425 Common - adenylosuccinate lyase Pmen_2402 233 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 146308993 Common - hypothetical protein Pmen_3979 3 None None None 146305306 Common - protein of unknown function DUF484 Pmen_0265 56 COG3159 COG3159, Uncharacterized protein conserved in bacteria Function unknown 146306385 Common - methyl-accepting chemotaxis sensory transducer Pmen_1353 113 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146309532 Common - GCN5-related N-acetyltransferase Pmen_4518 85 COG2153 ElaA, Predicted acyltransferase General function prediction only 146306026 Common - ribosomal-protein-alanine acetyltransferase Pmen_0991 174 COG0456 RimI, Acetyltransferases General function prediction only 146306876 Common - 3-demethylubiquinone-9 3-methyltransferase Pmen_1845 194 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 146309060 Common - TRAP dicarboxylate transporter, DctP subunit Pmen_4046 114 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 146305426 Common - transcriptional regulator of molybdate metabolism, LysR family Pmen_0386 68 COG1910 COG1910, Periplasmic molybdate-binding protein/domain Inorganic ion transport and metabolism 146306730 Common - maleylacetoacetate isomerase Pmen_1699 97 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 146305946 Common - LppC family lipoprotein Pmen_0911 47 COG3107 LppC, Putative lipoprotein General function prediction only 146309190 Common - peptidase M16 domain protein Pmen_4176 192 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 146306576 Common - 3-oxoacyl-(acyl carrier protein) synthase III Pmen_1545 199 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 146309288 Pathogen - hypothetical protein Pmen_4274 1 None None None 146307200 Common - hypothetical protein Pmen_2173 4 None None None 146306308 Common - TonB family protein Pmen_1276 10 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 146308415 Common xerD site-specific tyrosine recombinase XerD Pmen_3396 232 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 146308911 Common rplE 50S ribosomal protein L5 Pmen_3897 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 146307011 Common - putative transcriptional regulator, MerR family Pmen_1983 99 COG0789 SoxR, Predicted transcriptional regulators Transcription 146305813 Common - nicotinate-nucleotide pyrophosphorylase Pmen_0778 204 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 146309201 Common - aldehyde dehydrogenase Pmen_4187 219 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 146308524 Common - iron-sulfur cluster assembly protein IscA Pmen_3509 164 COG0316 IscA, Uncharacterized conserved protein Function unknown 146307408 Common - CrcB protein Pmen_2385 20 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 146309321 Common - diguanylate cyclase with PAS/PAC sensor Pmen_4307 189 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 146305529 Common - electron transfer flavoprotein beta-subunit Pmen_0492 17 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 146309632 Common trmE tRNA modification GTPase TrmE Pmen_4619 225 COG0486 ThdF, Predicted GTPase General function prediction only 146309512 Common - ABC-3 protein Pmen_4498 86 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 146309427 Pathogen - flagellar export protein FliJ Pmen_4413 4 None None None 146308403 Common - Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase and related enzymes-like protein Pmen_3384 55 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 146305506 Common - periplasmic/7TM domain sensor diguanylate cyclase Pmen_0469 179 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 146309043 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) Pmen_4029 201 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 146305922 Common - TonB-dependent siderophore receptor Pmen_0887 120 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 146305805 Common - hypothetical protein Pmen_0770 1 None None None 146308068 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase Pmen_3047 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 146308028 Common - metal dependent phosphohydrolase Pmen_3006 112 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 146308290 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Pmen_3270 145 COG0388 COG0388, Predicted amidohydrolase General function prediction only 146305535 Common - transcriptional regulator, AraC family Pmen_0498 149 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 146305638 Common - hypothetical protein Pmen_0603 1 COG3204 COG3204, Uncharacterized protein conserved in bacteria Function unknown 146306005 Common - protein of unknown function DUF152 Pmen_0970 180 COG1496 COG1496, Uncharacterized conserved protein Function unknown 146307405 Common - Glutathione S-transferase, C-terminal domain Pmen_2382 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 146309437 Common - export protein FliQ, family 3 Pmen_4423 48 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 146308668 Common - metal-dependent hydrolase-like protein Pmen_3653 26 COG3687 COG3687, Predicted metal-dependent hydrolase General function prediction only 146308584 Pathogen - hypothetical protein Pmen_3569 1 None None None 146306798 Common - membrane protein involved in aromatic hydrocarbon degradation Pmen_1767 87 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 146305714 Common - hypothetical protein Pmen_0679 1 None None None 146306685 Common - Methyltransferase type 11 Pmen_1654 42 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 146307227 Common - protein of unknown function DUF182 Pmen_2200 114 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 146307143 Pathogen - hypothetical protein Pmen_2115 1 None None None 146307270 Common - membrane protein-like protein Pmen_2244 103 COG1238 COG1238, Predicted membrane protein Function unknown 146305932 Common - helix-turn-helix- domain containing protein, AraC type Pmen_0897 152 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 146306665 Common - DNA polymerase III subunit delta' Pmen_1634 183 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 146307661 Common - AraC-type transcriptional regulator domain protein Pmen_2638 126 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 146307002 Common - hypothetical protein Pmen_1974 15 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 146309411 Common - ATP-dependent DNA helicase RecG Pmen_4397 214 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 146308898 Common - DNA-directed RNA polymerase subunit alpha Pmen_3884 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 146306652 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Pmen_1621 199 COG0546 Gph, Predicted phosphatases General function prediction only 146307781 Common - hypothetical protein Pmen_2759 51 COG3195 COG3195, Uncharacterized protein conserved in bacteria Function unknown 146308965 Common - hypothetical protein Pmen_3951 16 None None None 146308646 Common - sodium:neurotransmitter symporter Pmen_3631 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 146309498 Common - hypothetical protein Pmen_4484 1 None None None 146305866 Common - tRNA (uracil-5-)-methyltransferase Pmen_0831 187 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 146305393 Common - acetylornithine deacetylase Pmen_0353 174 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 146307716 Common - Carbamoyl-phosphate synthase L chain, ATP-binding Pmen_2694 239 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 146309443 Common - acyl-CoA dehydrogenase domain protein Pmen_4429 160 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 146307155 Common - hypothetical protein Pmen_2128 1 None None None 146308074 Common rpsB 30S ribosomal protein S2 Pmen_3053 230 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 146308258 Common - helix-turn-helix- domain containing protein, AraC type Pmen_3238 116 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 146307987 Common - protein of unknown function DUF1282 Pmen_2965 21 None None None 146307813 Common - heme exporter protein CcmA Pmen_2791 249 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 146305243 Common glcE glycolate oxidase FAD binding subunit Pmen_0202 160 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 146308157 Common lamB maltoporin Pmen_3137 27 COG4580 LamB, Maltoporin (phage lambda and maltose receptor) Carbohydrate transport and metabolism 146308717 Common - short chain dehydrogenase Pmen_3702 110 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 146309374 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Pmen_4360 33 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 146308754 Common - ATP-dependent helicase HrpB Pmen_3739 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 146308612 Common - acetyl-CoA acetyltransferase Pmen_3597 184 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 146307745 Common - isopropylmalate isomerase large subunit Pmen_2723 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 146305297 Common - transcriptional regulator, LysR family Pmen_0256 97 COG0583 LysR, Transcriptional regulator Transcription 146309402 Common gmk guanylate kinase Pmen_4388 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 146308432 Pathogen - hypothetical protein Pmen_3413 1 COG3369 COG3369, Uncharacterized conserved protein Function unknown 146305516 Common - ATP-dependent RNA helicase DbpA Pmen_0479 239 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 146308244 Common - Glutathione S-transferase, N-terminal domain Pmen_3224 105 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 146305672 Common - HflK protein Pmen_0637 217 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 146308931 Common rplL 50S ribosomal protein L7/L12 Pmen_3917 213 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 146309129 Common - IS66 Orf2 family protein Pmen_4115 50 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 146305693 Common - Azurin Pmen_0658 19 COG3241 COG3241, Azurin Energy production and conversion 146307277 Pathogen - hypothetical protein Pmen_2251 1 None None None 146307981 Common - hypothetical protein Pmen_2959 12 COG3089 COG3089, Uncharacterized protein conserved in bacteria Function unknown 146308338 Common - hypothetical protein Pmen_3318 4 None None None 146307824 Common - CheA signal transduction histidine kinase Pmen_2802 151 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 146305838 Common - putative hydroxylase Pmen_0803 44 COG3128 PiuC, Uncharacterized iron-regulated protein Function unknown 146309052 Common - Methyltransferase type 12 Pmen_4038 65 COG4301 COG4301, Uncharacterized conserved protein Function unknown 146305231 Common - hypothetical protein Pmen_0190 8 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 146307289 Common - hypothetical protein Pmen_2264 13 COG1981 COG1981, Predicted membrane protein Function unknown 146306977 Common - hypothetical protein Pmen_1949 17 None None None 146305706 Common - Auxin Efflux Carrier Pmen_0671 92 COG0679 COG0679, Predicted permeases General function prediction only 146305341 Common - polyphosphate kinase Pmen_0300 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 146309160 Common - Radical SAM domain protein Pmen_4146 55 COG4277 COG4277, Predicted DNA-binding protein with the Helix-hairpin-helix motif General function prediction only 146307127 Pathogen - hypothetical protein Pmen_2099 1 None None None 146308263 Common - protein of unknown function DUF488 Pmen_3243 77 COG3189 COG3189, Uncharacterized conserved protein Function unknown 146305994 Pathogen - Tfp pilus assembly protein PilX-like protein Pmen_0959 1 COG4726 PilX, Tfp pilus assembly protein PilX Cell motility and secretion / Intracellular trafficking and secretion 146306222 Common - hypothetical protein Pmen_1190 8 None None None 146305652 Common - Uncharacterized membrane protein affecting hemolysin expression-like protein Pmen_0617 4 COG3726 AhpA, Uncharacterized membrane protein affecting hemolysin expression General function prediction only 146309199 Common - response regulator receiver protein Pmen_4185 194 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 146305192 Common - electron transport protein SCO1/SenC Pmen_0151 105 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 146309557 Common - putative CBS domain and cyclic nucleotide-regulated nucleotidyltransferase Pmen_4543 129 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 146308316 Common - protein of unknown function DUF1111 Pmen_3296 49 COG3488 COG3488, Predicted thiol oxidoreductase Energy production and conversion 146305899 Common - hypothetical protein Pmen_0864 59 COG3028 COG3028, Uncharacterized protein conserved in bacteria Function unknown 146306636 Common - hypothetical protein Pmen_1605 6 None None None 146305621 Common - lipopolysaccharide kinase Pmen_0584 8 None None None 146305082 Common - ATPase, FliI/YscN family Pmen_0041 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 146306057 Common - hypothetical protein Pmen_1022 8 None None None 146309273 Common - A/G-specific adenine glycosylase Pmen_4259 228 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 146309484 Common - binding-protein-dependent transport systems inner membrane component Pmen_4470 144 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 146306033 Common - cyclic nucleotide-binding protein Pmen_0998 77 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 146308047 Common ispF 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Pmen_3026 189 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 146307131 Common - nitrate ABC transporter, ATPase subunits C and D Pmen_2103 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 146308778 Common - CRISPR-associated helicase Cas3 Pmen_3763 89 COG1203 COG1203, Predicted helicases General function prediction only 146307195 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Pmen_2168 62 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 146306252 Common - ABC transporter related Pmen_1220 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 146305489 Common - protein of unknown function DUF1090 Pmen_0452 16 None None None 146307545 Common - aminotransferase AlaT Pmen_2522 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 146309083 Common - histidine ammonia-lyase Pmen_4069 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 146308310 Common folX D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase Pmen_3290 59 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 146305738 Common - urea amidolyase related protein Pmen_0703 230 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 146306599 Common - CheA signal transduction histidine kinase Pmen_1568 153 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 146305248 Common flgC flagellar basal body rod protein FlgC Pmen_0207 108 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 146306563 Common - histidine triad (HIT) protein Pmen_1532 236 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 146309356 Common - sigma-54 factor, interaction domain-containing protein Pmen_4342 167 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 146307835 Common - flagellar biosynthesis protein, FliO Pmen_2813 18 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 146305455 Common - iron-containing alcohol dehydrogenase Pmen_0415 173 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 146305278 Common - aldehyde dehydrogenase Pmen_0237 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 146305676 Common - adenylosuccinate synthetase Pmen_0641 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 146306918 Common - AlkA domain protein Pmen_1888 115 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 146308781 Common - integral membrane sensor hybrid histidine kinase Pmen_3766 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146308856 Common - Pyruvate carboxylase., Propionyl-CoA carboxylase Pmen_3842 232 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 146305326 Common - anti-RNA polymerase sigma 70 factor Pmen_0285 24 COG3160 Rsd, Regulator of sigma D Transcription 146308032 Common - ribosome modulation factor Pmen_3010 21 COG3130 Rmf, Ribosome modulation factor Translation, ribosomal structure and biogenesis 146309258 Common - glutaredoxin 3 Pmen_4244 126 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 146308265 Common - branched-chain alpha-keto acid dehydrogenase subunit E2 Pmen_3245 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 146307846 Common fliG flagellar motor switch protein G Pmen_2824 124 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 146306149 Common - hypothetical protein Pmen_1115 21 COG3602 COG3602, Uncharacterized protein conserved in bacteria Function unknown 146305076 Pathogen - hypothetical protein Pmen_0034 1 None None None 146305484 Common - hypothetical protein Pmen_0447 6 None None None 146309215 Common - Spermidine/putrescine-binding periplasmic protein-like protein Pmen_4201 39 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 146305572 Common argS arginyl-tRNA synthetase Pmen_0535 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 146307346 Common - ImpA domain protein Pmen_2321 27 COG3515 COG3515, Uncharacterized protein conserved in bacteria Function unknown 146305129 Common - Aldose 1-epimerase Pmen_0088 60 COG0676 COG0676, Uncharacterized enzymes related to aldose 1-epimerase Carbohydrate transport and metabolism 146306725 Common - DSBA oxidoreductase Pmen_1694 27 COG3531 COG3531, Predicted protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 146306992 Common - aldehyde dehydrogenase Pmen_1964 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 146306750 Common - protein of unknown function DUF1329 Pmen_1719 18 None None None 146306102 Common - amine oxidase Pmen_1068 71 COG2907 COG2907, Predicted NAD/FAD-binding protein General function prediction only 146306114 Common - extracellular solute-binding protein, family 3 Pmen_1080 54 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146309416 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Pmen_4402 211 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 146306189 Common - Aldose 1-epimerase Pmen_1155 52 COG0676 COG0676, Uncharacterized enzymes related to aldose 1-epimerase Carbohydrate transport and metabolism 146306494 Common - putative signal transduction protein Pmen_1462 51 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 146309247 Common - protein of unknown function DUF523 Pmen_4233 65 COG1683 COG1683, Uncharacterized conserved protein Function unknown 146305910 Common - KpsF/GutQ family protein Pmen_0875 198 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 146305917 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Pmen_0882 211 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 146309469 Common - aminopeptidase-like protein Pmen_4455 16 COG4324 COG4324, Predicted aminopeptidase General function prediction only 146308766 Pathogen - hypothetical protein Pmen_3751 1 None None None 146309528 Common - TRAP dicarboxylate transporter- DctP subunit Pmen_4514 107 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 146309394 Common - acetylglutamate kinase Pmen_4380 219 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 146305665 Common - carbohydrate kinase, YjeF related protein Pmen_0630 211 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 146305969 Common - hypothetical protein Pmen_0934 172 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 146306126 Common - polar amino acid ABC transporter, inner membrane subunit Pmen_1092 172 COG4160 ArtM, ABC-type arginine/histidine transport system, permease component Amino acid transport and metabolism 146308190 Common - hypothetical protein Pmen_3170 3 None None None 146308655 Common - nitroreductase Pmen_3640 114 COG0778 NfnB, Nitroreductase Energy production and conversion 146309031 Common - putative serine protein kinase, PrkA Pmen_4017 69 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 146305197 Common - Cytochrome c5-like protein Pmen_0156 43 COG3245 CycB, Cytochrome c5 Energy production and conversion 146306863 Pathogen - hypothetical protein Pmen_1832 1 None None None 146305157 Common - Transglycosylase-associated protein Pmen_0116 32 COG2261 COG2261, Predicted membrane protein Function unknown 146308843 Common - protein of unknown function DUF980 Pmen_3828 57 COG3228 COG3228, Uncharacterized protein conserved in bacteria Function unknown 146306435 Common - electron transport complex protein RnfB Pmen_1403 119 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 146307788 Common - molybdenum cofactor biosynthesis protein A Pmen_2766 202 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 146306585 Common - hypothetical protein Pmen_1554 62 COG3220 COG3220, Uncharacterized protein conserved in bacteria Function unknown 146308378 Common adk adenylate kinase Pmen_3359 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 146307828 Common - Cobyrinic acid a,c-diamide synthase Pmen_2806 176 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 146307216 Common - putative transcriptional regulator, GntR family Pmen_2189 182 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 146309583 Common - cobalt-precorrin-6x reductase Pmen_4569 52 COG2099 CobK, Precorrin-6x reductase Coenzyme metabolism 146308051 Common - hypothetical protein Pmen_3030 19 None None None 146306407 Common - acyl-CoA dehydrogenase domain protein Pmen_1375 159 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 146306607 Common - ABC transporter related Pmen_1576 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 146307245 Common - hypothetical protein Pmen_2218 1 None None None 146306773 Common - protein of unknown function DUF903 Pmen_1742 7 None None None 146308518 Common - radical SAM enzyme, Cfr family Pmen_3503 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 146309301 Common - mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase Pmen_4287 164 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 146307044 Common - Endoribonuclease L-PSP Pmen_2016 119 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 146309169 Common metX homoserine O-acetyltransferase Pmen_4155 133 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 146306267 Common minC septum formation inhibitor Pmen_1235 84 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 146307175 Common - hypothetical protein Pmen_2148 1 None None None 146307932 Common - Arginine N-succinyltransferase Pmen_2910 37 COG3138 AstA, Arginine/ornithine N-succinyltransferase beta subunit Amino acid transport and metabolism 146305976 Common - hypothetical protein Pmen_0941 107 None None None 146307041 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pmen_2013 34 COG3565 COG3565, Predicted dioxygenase of extradiol dioxygenase family General function prediction only 146305180 Common - glutaminase Pmen_0139 72 COG2066 GlsA, Glutaminase Amino acid transport and metabolism 146308405 Common - hypothetical protein Pmen_3386 12 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 146308547 Common - Citrate transporter Pmen_3532 64 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 146308919 Common rpsS 30S ribosomal protein S19 Pmen_3905 245 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 146309455 Common - ABC-type amino acid transport/signal transduction systems periplasmic component/domain-like protein Pmen_4441 12 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146305348 Common - GntR domain protein Pmen_0307 112 COG2186 FadR, Transcriptional regulators Transcription 146305880 Common - extracellular solute-binding protein, family 5 Pmen_0845 209 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 146307282 Common - membrane protein-like protein Pmen_2256 25 COG3205 COG3205, Predicted membrane protein Function unknown 146305462 Common - conserved hypothetical protein 730 Pmen_0422 45 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 146307935 Common - ABC transporter related Pmen_2913 249 COG4598 HisP, ABC-type histidine transport system, ATPase component Amino acid transport and metabolism 146308714 Common - transcriptional regulator, TetR family Pmen_3699 39 COG1309 AcrR, Transcriptional regulator Transcription 146307415 Common infA translation initiation factor IF-1 Pmen_2392 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 146308097 Common - GCN5-related N-acetyltransferase Pmen_3076 58 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 146307359 Common - hypothetical protein Pmen_2334 24 COG5351 COG5351, Uncharacterized protein conserved in bacteria Function unknown 146307617 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pmen_2594 64 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 146308056 Common - CTP synthetase Pmen_3035 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 146308672 Pathogen - hypothetical protein Pmen_3657 1 None None None 146309154 Common - glutamine synthetase, type I Pmen_4140 226 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 146305664 Common - putative iron-sulfur cluster binding protein Pmen_0629 134 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 146305511 Common - intradiol ring-cleavage dioxygenase Pmen_0474 58 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 146306171 Common - short chain fatty acid transporter Pmen_1137 47 COG2031 AtoE, Short chain fatty acids transporter Lipid metabolism 146309612 Common - permease for cytosine/purine, uracil, thiamine, allantoin Pmen_4598 53 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 146309213 Common - putative RNA methylase Pmen_4199 137 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 146307799 Common - acriflavin resistance protein Pmen_2777 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 146307350 Common - hypothetical protein Pmen_2325 5 None None None 146309537 Common - transcriptional regulator, GntR family Pmen_4523 120 COG1802 GntR, Transcriptional regulators Transcription 146309141 Common - formyltetrahydrofolate deformylase Pmen_4127 218 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 146308953 Common - AAA ATPase, central domain protein Pmen_3939 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 146307299 Common - outer membrane protein-like protein Pmen_2274 34 COG3652 COG3652, Predicted outer membrane protein Function unknown 146306097 Common - glutamate racemase Pmen_1063 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 146305086 Pathogen - surface presentation of antigens (SPOA) protein Pmen_0045 2 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 146307057 Common - hydroxymethylglutaryl-CoA lyase Pmen_2029 132 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 146306070 Common - MoaD family protein Pmen_1035 57 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 146306300 Common aspS aspartyl-tRNA synthetase Pmen_1268 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 146305331 Common - hypothetical protein Pmen_0290 16 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 146306012 Common - diguanylate cyclase with PAS/PAC sensor Pmen_0977 185 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 146305552 Common - protein of unknown function DUF558 Pmen_0515 42 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 146309147 Pathogen - hypothetical protein Pmen_4133 1 None None None 146306869 Common - chromosome segregation and condensation protein ScpA Pmen_1838 140 COG1354 COG1354, Uncharacterized conserved protein Function unknown 146306249 Common - d-galactonate transporter Pmen_1217 181 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 146305718 Common - integral membrane protein-like protein Pmen_0683 50 COG0392 COG0392, Predicted integral membrane protein Function unknown 146308918 Common rplV 50S ribosomal protein L22 Pmen_3904 224 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 146305525 Common - Substrate-binding region of ABC-type glycine betaine transport system Pmen_0488 60 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 146305250 Common - flagellar basal body FlaE domain protein Pmen_0209 127 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 146306670 Common - molybdenum cofactor synthesis domain protein Pmen_1639 198 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 146306778 Common - NLP/P60 protein Pmen_1747 133 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 146305563 Common - poly(hydroxyalkanoate) granule-associated protein Pmen_0526 16 COG3937 COG3937, Uncharacterized conserved protein Function unknown 146309578 Common - transport system permease protein Pmen_4564 190 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 146307635 Common - hypothetical protein Pmen_2612 32 COG2836 COG2836, Uncharacterized conserved protein Function unknown 146308800 Common - hypothetical protein Pmen_3785 1 None None None 146306848 Common - conserved hypothetical selenoprotein Pmen_1817 29 COG3526 COG3526, Uncharacterized protein conserved in bacteria Posttranslational modification, protein turnover, chaperones 146306210 Pathogen - hypothetical protein Pmen_1178 1 None None None 146306562 Common - Glutathione S-transferase, N-terminal domain Pmen_1531 100 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 146306269 Common - Patatin Pmen_1237 75 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 146309079 Common - diguanylate cyclase Pmen_4065 107 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 146306790 Common cobS cobalamin synthase Pmen_1759 22 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 146305988 Common ileS isoleucyl-tRNA synthetase Pmen_0953 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 146307950 Common - NAD-glutamate dehydrogenase Pmen_2928 77 COG2902 COG2902, NAD-specific glutamate dehydrogenase Amino acid transport and metabolism 146306834 Common - ABC transporter related Pmen_1803 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 146309406 Common - hypothetical protein Pmen_4392 1 None None None 146308903 Common secY preprotein translocase subunit SecY Pmen_3889 228 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 146307273 Common - chromate transporter, chromate ion transporter (CHR) family Pmen_2247 115 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 146305639 Common - DNA topoisomerase IV subunit B Pmen_0604 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 146306459 Common dinG ATP-dependent DNA helicase DinG Pmen_1427 133 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 146306371 Common - outer membrane porin Pmen_1339 8 None None None 146306364 Common - ABC-type Fe3+ transport system periplasmic component-like protein Pmen_1332 59 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 146305674 Common - hypothetical protein Pmen_0639 4 COG3242 COG3242, Uncharacterized protein conserved in bacteria Function unknown 146306138 Common - dihydrolipoamide dehydrogenase Pmen_1104 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 146307338 Common - protein kinase Pmen_2313 160 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 146308751 Common - Endonuclease/exonuclease/phosphatase Pmen_3736 11 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 146305071 Pathogen - type III secretion apparatus protein, YscI/HrpB family Pmen_0029 1 None None None 146308873 Common - hypothetical protein Pmen_3859 1 COG3126 COG3126, Uncharacterized protein conserved in bacteria Function unknown 146306309 Common tolB translocation protein TolB Pmen_1277 154 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 146305338 Common - Sterol desaturase-like protein Pmen_0297 75 COG3000 ERG3, Sterol desaturase Lipid metabolism 146307875 Common flgA flagellar basal body P-ring biosynthesis protein FlgA Pmen_2853 64 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 146305949 Common mraW S-adenosyl-methyltransferase MraW Pmen_0914 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 146308503 Common - transmembrane pair domain protein Pmen_3488 41 COG4125 COG4125, Predicted membrane protein Function unknown 146307446 Common - NADH dehydrogenase subunit M Pmen_2423 209 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 146308747 Common - protein of unknown function UPF0259 Pmen_3732 7 None None None 146309179 Common - protein of unknown function DUF1329 Pmen_4165 18 None None None 146308003 Common - periplasmic nitrate reductase, large subunit Pmen_2981 187 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 146306027 Common - Rieske (2Fe-2S) domain protein Pmen_0992 42 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 146306590 Common - FAD dependent oxidoreductase Pmen_1559 148 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 146308728 Common - hypothetical protein Pmen_3713 1 None None None 146305861 Common - transporter, hydrophobe/amphiphile efflux-1 (HAE1) family Pmen_0826 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 146306862 Common - two component transcriptional regulator, winged helix family Pmen_1831 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 146308441 Pathogen - hypothetical protein Pmen_3422 1 None None None 146307870 Common flgD flagellar basal body rod modification protein Pmen_2848 68 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 146309622 Common - F0F1 ATP synthase subunit alpha Pmen_4609 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 146305149 Common - glycoside hydrolase, family 19 Pmen_0108 20 COG3179 COG3179, Predicted chitinase General function prediction only 146307587 Common - Triacylglycerol lipase Pmen_2564 21 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 146307743 Common - 3-isopropylmalate dehydrogenase Pmen_2721 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 146305635 Common - protein of unknown function DUF330 Pmen_0600 8 COG3009 COG3009, Uncharacterized protein conserved in bacteria Function unknown 146305375 Common - protein of unknown function DUF395, YeeE/YedE Pmen_0335 65 COG2391 COG2391, Predicted transporter component General function prediction only 146305651 Common - hypothetical protein Pmen_0616 1 None None None 146308466 Common - binding-protein-dependent transport systems inner membrane component Pmen_3449 196 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 146306054 Common - hypothetical protein Pmen_1019 1 None None None 146305094 Common - sun protein Pmen_0053 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 146308322 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Pmen_3302 41 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 146306678 Common - intracellular protease, PfpI family Pmen_1647 162 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 146306859 Common - nitroreductase Pmen_1828 88 COG0778 NfnB, Nitroreductase Energy production and conversion 146305495 Common - transketolase Pmen_0458 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 146309281 Common - hypothetical protein Pmen_4267 4 None None None 146305974 Common - nucleotide-binding protein Pmen_0939 107 COG1666 COG1666, Uncharacterized protein conserved in bacteria Function unknown 146306692 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Pmen_1661 214 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 146308069 Common - Phosphatidate cytidylyltransferase Pmen_3048 212 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 146308090 Common - putative cold-shock DNA-binding domain protein Pmen_3069 179 COG1278 CspC, Cold shock proteins Transcription 146305135 Pathogen - hypothetical protein Pmen_0094 1 None None None 146308852 Common - hypothetical protein Pmen_3838 8 None None None 146307537 Common - protein of unknown function DUF6, transmembrane Pmen_2514 60 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 146307424 Common - protein of unknown function DUF6, transmembrane Pmen_2401 98 COG2962 RarD, Predicted permeases General function prediction only 146307961 Common - aminopeptidase N Pmen_2939 161 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 146306898 Common - glycosyl transferase, family 2 Pmen_1868 2 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 146307991 Common - L-carnitine dehydratase/bile acid-inducible protein F Pmen_2969 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 146305142 Common - hypothetical protein Pmen_0101 31 COG3521 COG3521, Uncharacterized protein conserved in bacteria Function unknown 146309104 Common - amidophosphoribosyltransferase-like protein Pmen_4090 117 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 146308583 Common - YheO domain protein Pmen_3568 45 COG2964 COG2964, Uncharacterized protein conserved in bacteria Function unknown 146307109 Common - methylcitrate synthase Pmen_2081 194 COG0372 GltA, Citrate synthase Energy production and conversion 146307755 Common gltX glutamyl-tRNA synthetase Pmen_2733 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 146308281 Common - pyruvate kinase Pmen_3261 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 146308105 Common - transposase IS66 Pmen_3084 67 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 146305109 Common - aldo/keto reductase Pmen_0068 177 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 146306255 Common - ATP-dependent protease La Pmen_1223 210 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 146307553 Common - predicted inner membrane peptidase Pmen_2530 186 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 146308973 Pathogen - hypothetical protein Pmen_3959 1 None None None 146306742 Common - bacteriophage N4 receptor, outer membrane subunit Pmen_1711 4 None None None 146307973 Common - NADH:flavin oxidoreductase/NADH oxidase Pmen_2951 180 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 146305259 Common - TRAP dicarboxylate transporter, DctP subunit Pmen_0218 97 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 146308610 Common - acetyl-CoA synthetase Pmen_3595 216 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 146308787 Common - phosphomethylpyrimidine kinase Pmen_3772 220 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 146308345 Common - LemA family protein Pmen_3325 131 COG1704 LemA, Uncharacterized conserved protein Function unknown 146308823 Common - LrgB family protein Pmen_3808 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 146306736 Common - protein of unknown function UPF0066 Pmen_1705 96 COG1720 COG1720, Uncharacterized conserved protein Function unknown 146309503 Common - hypothetical protein Pmen_4489 4 None None None 146309226 Common - GTP-binding protein, HSR1-related Pmen_4212 17 COG0486 ThdF, Predicted GTPase General function prediction only 146308017 Common - hypothetical protein Pmen_2995 20 COG3249 COG3249, Uncharacterized protein conserved in bacteria Function unknown 146305612 Common aceF dihydrolipoamide acetyltransferase Pmen_0575 203 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 146305685 Common - alanine racemase Pmen_0650 199 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 146309462 Common - Antibiotic biosynthesis monooxygenase Pmen_4448 38 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 146308551 Common - Citrate transporter Pmen_3536 45 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 146305472 Common - IS66 Orf2 family protein Pmen_0433 20 None None None 146305144 Common - hypothetical protein Pmen_0103 50 COG3455 COG3455, Uncharacterized protein conserved in bacteria Function unknown 146309600 Common cobN cobaltochelatase Pmen_4586 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 146309191 Common - peptidase M16 domain protein Pmen_4177 169 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 146307388 Common - Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase-like protein Pmen_2363 73 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 146305400 Common - integral membrane sensor signal transduction histidine kinase Pmen_0360 164 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146309170 Common - methionine biosynthesis protein MetW Pmen_4156 68 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 146308330 Common - hypothetical protein Pmen_3310 1 None None None 146306500 Common - anti sigma-E protein, RseA Pmen_1468 4 COG3073 RseA, Negative regulator of sigma E activity Signal transduction mechanisms 146305778 Common - helix-turn-helix- domain containing protein, AraC type Pmen_0743 78 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 146308707 Common - protein of unknown function DUF450 Pmen_3692 37 COG4748 COG4748, Uncharacterized conserved protein Function unknown 146306234 Common - Uncharacterized protein UPF0114 Pmen_1202 55 COG2862 COG2862, Predicted membrane protein Function unknown 146308085 Common - UBA/THIF-type NAD/FAD binding protein Pmen_3064 128 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 146309207 Common - gamma-glutamyltransferase Pmen_4193 144 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 146309136 Common - methyl-accepting chemotaxis sensory transducer Pmen_4122 118 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146306926 Common - short-chain dehydrogenase/reductase SDR Pmen_1897 24 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 146305898 Common - peptidase U62, modulator of DNA gyrase Pmen_0863 170 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 146306284 Common - Hydrolase of the alpha/beta superfamily-like protein Pmen_1252 82 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 146305294 Common - ATP-dependent DNA helicase Rep Pmen_0253 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 146306327 Common - alpha/beta hydrolase fold Pmen_1295 208 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 146308555 Common - diguanylate cyclase Pmen_3540 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 146308619 Common - polynucleotide phosphorylase/polyadenylase Pmen_3604 244 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 146308974 Common - hypothetical protein Pmen_3960 2 None None None 146307100 Common - protein of unknown function DUF81 Pmen_2072 93 COG0730 COG0730, Predicted permeases General function prediction only 146308624 Common nusA transcription elongation factor NusA Pmen_3609 216 COG0195 NusA, Transcription elongation factor Transcription 146308033 Common - dihydroorotate dehydrogenase 2 Pmen_3011 232 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 146307021 Common - Propeptide, PepSY amd peptidase M4 Pmen_1993 4 COG3212 COG3212, Predicted membrane protein Function unknown 146305748 Common - acetyl-CoA carboxylase biotin carboxylase subunit Pmen_0713 233 COG0439 AccC, Biotin carboxylase Lipid metabolism 146306475 Common - putative monovalent cation/H+ antiporter subunit D Pmen_1443 162 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 146305752 Common - methyl-accepting chemotaxis sensory transducer Pmen_0717 139 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146307098 Common - hypothetical protein Pmen_2070 20 None None None 146307225 Common - (2Fe-2S)-binding domain protein Pmen_2198 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 146308566 Common - glutaredoxin Pmen_3551 27 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 146306581 Pathogen - hypothetical protein Pmen_1550 1 None None None 146309096 Common - hypothetical protein Pmen_4082 19 None None None 146308590 Common - globin Pmen_3575 59 COG2346 COG2346, Truncated hemoglobins General function prediction only 146306176 Common - Uncharacterized MobA-related protein-like protein Pmen_1142 82 COG2068 COG2068, Uncharacterized MobA-related protein General function prediction only 146308293 Common - hypothetical protein Pmen_3273 29 COG4321 COG4321, Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis General function prediction only 146308987 Common - phage Terminase Pmen_3973 44 COG4626 COG4626, Phage terminase-like protein, large subunit General function prediction only 146306461 Pathogen - multiple resistance and pH regulation protein F Pmen_1429 1 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 146309473 Common - GCN5-related N-acetyltransferase Pmen_4459 31 COG0456 RimI, Acetyltransferases General function prediction only 146307176 Common - periplasmic binding protein/LacI transcriptional regulator Pmen_2149 35 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 146305615 Common - branched-chain amino acid aminotransferase Pmen_0578 219 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 146306961 Common - putative ferric uptake regulator, Fur family Pmen_1932 11 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 146309021 Common - heat shock protein DnaJ domain protein Pmen_4007 53 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 146308019 Common purN phosphoribosylglycinamide formyltransferase Pmen_2997 220 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 146305188 Common - hypothetical protein Pmen_0147 47 COG3346 COG3346, Uncharacterized conserved protein Function unknown 146308949 Common - 2-nitropropane dioxygenase, NPD Pmen_3935 97 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 146305797 Common - putative ABC transporter ATP-binding protein Pmen_0762 247 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 146307217 Common - outer membrane porin Pmen_2190 6 None None None 146307833 Common fliQ flagellar biosynthesis protein FliQ Pmen_2811 126 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 146307064 Common - acetyl-CoA acetyltransferase Pmen_2036 172 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 146309180 Common trmB tRNA (guanine-N(7))-methyltransferase Pmen_4166 176 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 146308688 Common - hypothetical protein Pmen_3673 1 None None None 146305825 Common - Silent information regulator protein Sir2 Pmen_0790 152 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 146309485 Common - ABC transporter related Pmen_4471 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 146308193 Common - protein of unknown function DUF6, transmembrane Pmen_3173 160 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 146308544 Common - hypothetical protein Pmen_3529 1 None None None 146305760 Common - NUDIX hydrolase Pmen_0725 45 COG1443 Idi, Isopentenyldiphosphate isomerase Lipid metabolism 146305172 Common - FMN-binding negative transcriptional regulator Pmen_0131 60 COG2808 PaiB, Transcriptional regulator Transcription 146308010 Common - putative ribonuclease BN Pmen_2988 149 COG1295 Rbn, Predicted membrane protein Function unknown 146305229 Pathogen - hypothetical protein Pmen_0188 1 None None None 146306397 Common - binding-protein-dependent transport systems inner membrane component Pmen_1365 78 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 146306262 Common - phosphoheptose isomerase Pmen_1230 138 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 146309189 Common - signal recognition particle-docking protein FtsY Pmen_4175 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 146308148 Common - alpha amylase, catalytic region Pmen_3128 162 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 146306942 Common - putative GAF sensor protein Pmen_1913 82 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 146306931 Common - methyl-accepting chemotaxis sensory transducer Pmen_1902 161 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146306454 Common - OmpA/MotB domain protein Pmen_1422 168 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 146309445 Common - NAD(P)(+) transhydrogenase (AB-specific) Pmen_4431 166 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 146307301 Common - CinA domain protein Pmen_2276 192 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 146306079 Pathogen - hypothetical protein Pmen_1044 1 None None None 146309112 Common - DNA polymerase III, epsilon subunit Pmen_4098 108 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 146305790 Common - acetyltransferase-like protein Pmen_0755 12 COG5628 COG5628, Predicted acetyltransferase General function prediction only 146305784 Common - peptidase U62, modulator of DNA gyrase Pmen_0749 166 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 146309246 Common - D-3-phosphoglycerate dehydrogenase Pmen_4232 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 146305237 Common - flagellin domain protein Pmen_0196 123 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 146305859 Common - transcriptional regulator, TetR family Pmen_0824 82 COG1309 AcrR, Transcriptional regulator Transcription 146309439 Common flhB flagellar biosynthesis protein FlhB Pmen_4425 129 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 146309386 Common - putative signal transduction protein Pmen_4372 194 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 146309350 Common - protein of unknown function DUF395, YeeE/YedE Pmen_4336 4 None None None 146309041 Common dnaG DNA primase Pmen_4027 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 146309346 Common - outer membrane porin Pmen_4332 13 None None None 146308308 Common - short chain dehydrogenase Pmen_3288 217 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 146306632 Common - ApbE family lipoprotein Pmen_1601 138 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 146305696 Common - Lysine exporter protein (LYSE/YGGA) Pmen_0661 4 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 146309107 Common - RarD protein, DMT superfamily transporter Pmen_4093 95 COG2962 RarD, Predicted permeases General function prediction only 146305891 Common - cell shape determining protein, MreB/Mrl family Pmen_0856 236 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 146305875 Common - Alkaline phosphatase Pmen_0840 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 146308309 Common - GTP cyclohydrolase I Pmen_3289 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 146305836 Common - Ornithine decarboxylase Pmen_0801 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 146306966 Common - coenzyme PQQ biosynthesis protein PqqF Pmen_1937 148 COG1025 Ptr, Secreted/periplasmic Zn-dependent peptidases, insulinase-like Posttranslational modification, protein turnover, chaperones 146308214 Common - diguanylate cyclase/phosphodiesterase Pmen_3194 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 146307563 Common - para-aminobenzoate synthase, subunit I Pmen_2540 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 146306933 Common - SAM-dependent methyltransferase-like protein Pmen_1904 46 COG2933 COG2933, Predicted SAM-dependent methyltransferase General function prediction only 146305816 Common - signaling modulator of AmpD, AmpE Pmen_0781 32 COG3725 AmpE, Membrane protein required for beta-lactamase induction Defense mechanisms 146307124 Common - nitrite reductase (NAD(P)H), large subunit Pmen_2096 222 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 146308124 Common - hypothetical protein Pmen_3103 36 None None None 146308450 Common - hypothetical protein Pmen_3431 6 None None None 146308478 Common - methyl-accepting chemotaxis sensory transducer Pmen_3461 59 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146305433 Common nudE ADP-ribose diphosphatase NudE Pmen_0393 147 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 146306904 Common - NAD-dependent epimerase/dehydratase Pmen_1874 68 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 146307993 Common - acyl-CoA dehydrogenase domain protein Pmen_2971 158 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 146306785 Common - threonine-phosphate decarboxylase Pmen_1754 197 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 146305493 Common - transcriptional regulator, LysR family Pmen_0456 193 COG0583 LysR, Transcriptional regulator Transcription 146307286 Common - hypothetical protein Pmen_2261 7 None None None 146307371 Common - molybdopterin dehydrogenase, FAD-binding Pmen_2346 76 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 146307698 Pathogen - hypothetical protein Pmen_2676 1 None None None 146306388 Common - hypothetical protein Pmen_1356 6 None None None 146306536 Common - transcriptional regulator, LysR family Pmen_1504 1 COG0583 LysR, Transcriptional regulator Transcription 146308605 Common - poly(A) polymerase Pmen_3590 214 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 146309292 Common - Acetyltransferase (isoleucine patch superfamily)-like protein Pmen_4278 115 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 146308718 Common - hypothetical protein Pmen_3703 4 None None None 146308471 Common - ferredoxin Pmen_3454 105 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 146305449 Common - CheB methylesterase Pmen_0409 92 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 146307695 Common - RNA polymerase sigma factor Pmen_2673 30 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 146305559 Common - protein of unknown function DUF1243 Pmen_0522 49 COG3165 COG3165, Uncharacterized protein conserved in bacteria Function unknown 146306948 Common - ABC transporter related Pmen_1919 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 146305721 Common - periplasmic binding protein/LacI transcriptional regulator Pmen_0686 41 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 146306584 Pathogen - hypothetical protein Pmen_1553 1 COG3767 COG3767, Uncharacterized low-complexity protein Function unknown 146307730 Common - Electron-transferring-flavoprotein dehydrogenase Pmen_2708 108 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 146309561 Common - L-serine dehydratase 1 Pmen_4547 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 146307956 Common - hypothetical protein Pmen_2934 34 None None None 146307891 Common - amino acid adenylation domain Pmen_2869 216 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 146308731 Common - transporter, hydrophobe/amphiphile efflux-1 (HAE1) family Pmen_3716 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 146309255 Common - hypothetical protein Pmen_4241 1 None None None 146307251 Pathogen - hypothetical protein Pmen_2224 1 None None None 146307713 Common - Propionyl-CoA carboxylase Pmen_2691 144 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 146308485 Common - glutamine synthetase, catalytic region Pmen_3468 224 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 146307804 Common - hypothetical protein Pmen_2782 1 None None None 146308924 Common rpsJ 30S ribosomal protein S10 Pmen_3910 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 146306279 Common - hypothetical protein Pmen_1247 48 COG1742 COG1742, Uncharacterized conserved protein Function unknown 146308576 Common - Carboxylesterase Pmen_3561 87 COG0400 COG0400, Predicted esterase General function prediction only 146307565 Common - oxidoreductase FAD/NAD(P)-binding domain protein Pmen_2542 177 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 146306194 Common - hypothetical protein Pmen_1160 10 None None None 146308233 Common - transcriptional regulator, LysR family Pmen_3213 95 COG0583 LysR, Transcriptional regulator Transcription 146308264 Common - protein of unknown function DUF6, transmembrane Pmen_3244 27 None None None 146306880 Common - phosphoserine aminotransferase Pmen_1849 110 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 146307458 Common - GCN5-related N-acetyltransferase Pmen_2435 10 COG0456 RimI, Acetyltransferases General function prediction only 146308457 Common - flavin reductase domain protein, FMN-binding Pmen_3440 121 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 146307599 Common - UspA domain protein Pmen_2576 37 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 146305123 Common - thioesterase superfamily protein Pmen_0082 134 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 146307626 Pathogen - hypothetical protein Pmen_2603 1 None None None 146307532 Common - lipid-binding START domain protein Pmen_2509 17 None None None 146306682 Common - short-chain dehydrogenase/reductase SDR Pmen_1651 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 146307376 Common - glutathione reductase Pmen_2351 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 146308207 Common - RNA binding S1 domain protein Pmen_3187 44 COG2996 COG2996, Uncharacterized protein conserved in bacteria Function unknown 146308238 Common - methyl-accepting chemotaxis sensory transducer Pmen_3218 141 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146307646 Common - hypothetical protein Pmen_2623 42 COG3530 COG3530, Uncharacterized protein conserved in bacteria Function unknown 146309192 Common - putative methyltransferase Pmen_4178 127 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 146306839 Common - diguanylate cyclase/phosphodiesterase Pmen_1808 151 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 146305900 Common - peptidase U62, modulator of DNA gyrase Pmen_0865 155 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 146306499 Common algU RNA polymerase sigma factor AlgU Pmen_1467 171 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 146308331 Common - CBS domain containing protein Pmen_3311 115 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 146305906 Common - ABC transporter related Pmen_0871 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 146307182 Common - Radical SAM domain protein Pmen_2155 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 146307411 Common - cell divisionFtsK/SpoIIIE Pmen_2388 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 146305208 Common - hypothetical protein Pmen_0167 12 None None None 146306990 Common - hypothetical protein Pmen_1962 1 None None None 146308319 Common - NAD-dependent epimerase/dehydratase Pmen_3299 122 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 146306437 Common metG methionyl-tRNA synthetase Pmen_1405 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 146305246 Common - SAF domain Pmen_0205 43 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 146305735 Common - inner-membrane translocator Pmen_0700 125 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 146308693 Common - CreA family protein Pmen_3678 57 COG3045 CreA, Uncharacterized protein conserved in bacteria Function unknown 146306405 Common - Enoyl-CoA hydratase/isomerase Pmen_1373 100 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 146307177 Common - hypothetical protein Pmen_2150 10 None None None 146309159 Common - TM2 domain containing protein+B7201 Pmen_4145 21 COG2314 XynA, Predicted membrane protein Function unknown 146309395 Common - thioesterase superfamily protein Pmen_4381 87 COG0824 FcbC, Predicted thioesterase General function prediction only 146306147 Common - transcriptional regulator, LysR family Pmen_1113 129 COG0583 LysR, Transcriptional regulator Transcription 146306739 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pmen_1708 47 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 146308850 Common - inner-membrane translocator Pmen_3836 155 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 146306648 Common - protein tyrosine phosphatase Pmen_1617 138 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 146307326 Common - glutamate--cysteine ligase, GCS2 Pmen_2301 61 COG2170 COG2170, Uncharacterized conserved protein Function unknown 146306604 Common - MOSC domain containing protein Pmen_1573 74 COG3217 COG3217, Uncharacterized Fe-S protein General function prediction only 146307816 Common - Rhodanese domain protein Pmen_2794 28 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 146308380 Common - hypothetical protein Pmen_3361 6 None None None 146305894 Common - Maf-like protein Pmen_0859 196 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 146308643 Common - SmpA/OmlA domain protein Pmen_3628 63 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 146306601 Common - response regulator receiver protein Pmen_1570 222 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 146305915 Common - anti-sigma-factor antagonist Pmen_0880 3 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 146308756 Common - cation diffusion facilitator family transporter Pmen_3741 175 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 146309418 Common - Choline-glycine betaine transporter-like protein Pmen_4404 21 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 146305445 Common - putative CheW protein Pmen_0405 63 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 146309332 Common - sulfate ABC transporter, periplasmic sulfate-binding protein Pmen_4318 90 COG4150 CysP, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 146305061 Pathogen - Tir chaperone family protein Pmen_0019 1 None None None 146306539 Common - hypothetical protein Pmen_1507 1 None None None 146307390 Common - ABC transporter related Pmen_2365 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 146309235 Common - threonine dehydratase Pmen_4221 222 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 146309376 Common - esterase, PHB depolymerase family Pmen_4362 38 COG3509 LpqC, Poly(3-hydroxybutyrate) depolymerase Secondary metabolites biosynthesis, transport, and catabolism 146305075 Common - sigma54 specific transcriptional regulator, Fis family Pmen_0033 170 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 146308900 Common - 30S ribosomal protein S11 Pmen_3886 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 146309354 Common - molybdate ABC transporter, inner membrane subunit Pmen_4340 226 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 146305882 Common - integral membrane sensor signal transduction histidine kinase Pmen_0847 56 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146309559 Pathogen - hypothetical protein Pmen_4545 1 None None None 146308072 Common pyrH uridylate kinase Pmen_3051 237 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 146308407 Common - hypothetical protein Pmen_3388 9 None None None 146305450 Common - putative CheW protein Pmen_0410 9 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 146308657 Common - peptidylprolyl isomerase, FKBP-type Pmen_3642 108 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 146305765 Common - alpha-2-macroglobulin domain protein Pmen_0730 80 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 146305670 Common hfq RNA-binding protein Hfq Pmen_0635 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 146309183 Common - protein of unknown function DUF423 Pmen_4169 69 COG2363 COG2363, Uncharacterized small membrane protein Function unknown 146309618 Common - UDP-N-acetylglucosamine pyrophosphorylase Pmen_4605 237 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 146308491 Common - glycine cleavage T protein (aminomethyl transferase) Pmen_3474 182 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 146305807 Common coaE dephospho-CoA kinase Pmen_0772 205 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 146307518 Pathogen - hypothetical protein Pmen_2495 1 None None None 146307930 Common - aldehyde dehydrogenase Pmen_2908 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 146305113 Common - hypothetical protein Pmen_0072 7 None None None 146307523 Common sucC succinyl-CoA synthetase subunit beta Pmen_2500 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 146307218 Pathogen - hypothetical protein Pmen_2191 1 COG5637 COG5637, Predicted integral membrane protein Function unknown 146308062 Common - UDP-N-acetylglucosamine acyltransferase Pmen_3041 162 COG1043 LpxA, Acyl- acyl carrier protein 146307167 Common - phospho-2-dehydro-3-deoxyheptonate aldolase Pmen_2140 73 COG3200 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 146307046 Common - transcriptional regulator, LysR family Pmen_2018 183 COG0583 LysR, Transcriptional regulator Transcription 146305769 Common - methyl-accepting chemotaxis sensory transducer Pmen_0734 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146308054 Common eno phosphopyruvate hydratase Pmen_3033 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 146308683 Common - peptidase M48, Ste24p Pmen_3668 126 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 146306492 Common - integral membrane sensor signal transduction histidine kinase Pmen_1460 214 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146309145 Common - sarcosine oxidase, beta subunit family Pmen_4131 137 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 146309211 Common - formamidopyrimidine-DNA glycosylase Pmen_4197 181 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 146305577 Common - Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) Pmen_0540 202 COG0281 SfcA, Malic enzyme Energy production and conversion 146307581 Common - Lysophospholipase Pmen_2558 96 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 146307688 Common - hypothetical protein Pmen_2666 7 COG2267 PldB, Lysophospholipase Lipid metabolism 146306611 Common fadB multifunctional fatty acid oxidation complex subunit alpha Pmen_1580 178 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 146308266 Common - Transketolase, central region Pmen_3246 205 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 146309635 Common rnpA ribonuclease P Pmen_4622 77 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 146307344 Common - hypothetical protein Pmen_2319 33 COG3521 COG3521, Uncharacterized protein conserved in bacteria Function unknown 146307855 Common - flagellar hook-associated 2 domain protein Pmen_2833 112 COG1345 FliD, Flagellar capping protein Cell motility and secretion 146306667 Common - hydrolase, TatD family Pmen_1636 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 146305602 Common - hypothetical protein Pmen_0565 12 None None None 146306997 Common - pyrroloquinoline quinone biosynthesis protein PqqE Pmen_1969 156 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 146305066 Pathogen - hypothetical protein Pmen_0024 1 None None None 146308256 Common mdoG glucan biosynthesis protein G Pmen_3236 50 COG3131 MdoG, Periplasmic glucans biosynthesis protein Inorganic ion transport and metabolism 146305566 Common - poly(3-hydroxyalkanoate) depolymerase Pmen_0529 124 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 146306722 Common - hypothetical protein Pmen_1691 15 COG3184 COG3184, Uncharacterized protein conserved in bacteria Function unknown 146306502 Common - positive regulator of sigma E, RseC/MucC Pmen_1470 2 COG3086 RseC, Positive regulator of sigma E activity Signal transduction mechanisms 146308031 Common - putative RNA methylase Pmen_3009 163 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 146307880 Common - Glutamate--putrescine ligase Pmen_2858 224 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 146308045 Common surE stationary phase survival protein SurE Pmen_3024 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 146309133 Common - sensory histidine kinase CreC Pmen_4119 189 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146306883 Common - 3-phosphoshikimate 1-carboxyvinyltransferase Pmen_1852 231 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 146308375 Pathogen - hypothetical protein Pmen_3356 1 None None None 146309454 Common - Auxin Efflux Carrier Pmen_4440 52 COG0679 COG0679, Predicted permeases General function prediction only 146307766 Common folE GTP cyclohydrolase I Pmen_2744 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 146307945 Common - general secretion pathway protein G Pmen_2923 76 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 146306638 Common - lipoprotein releasing system, transmembrane protein, LolC/E family Pmen_1607 157 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 146308311 Common - protein of unknown function DUF1244 Pmen_3291 38 COG3492 COG3492, Uncharacterized protein conserved in bacteria Function unknown 146305389 Common - Ornithine carbamoyltransferase Pmen_0349 192 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 146307676 Common - hypothetical protein Pmen_2654 29 COG5569 COG5569, Uncharacterized conserved protein Function unknown 146309580 Common - ABC transporter related Pmen_4566 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 146307715 Common - Enoyl-CoA hydratase/isomerase Pmen_2693 155 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 146306809 Common - hypothetical protein Pmen_1778 26 None None None 146307983 Common - phospho-2-dehydro-3-deoxyheptonate aldolase Pmen_2961 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 146305395 Common - hypothetical protein Pmen_0355 3 COG3130 Rmf, Ribosome modulation factor Translation, ribosomal structure and biogenesis 146308542 Common - leucyl aminopeptidase Pmen_3527 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 146309006 Common - hypothetical protein Pmen_3992 4 None None None 146308242 Common - hypothetical protein Pmen_3222 1 None None None 146309552 Common - protein of unknown function DUF198 Pmen_4538 27 COG1469 COG1469, Uncharacterized conserved protein Function unknown 146305729 Common - GCN5-related N-acetyltransferase Pmen_0694 126 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 146308155 Common - protein of unknown function DUF1568 Pmen_3135 53 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 146305850 Pathogen - hypothetical protein Pmen_0815 1 None None None 146308570 Common - protein of unknown function DUF1486 Pmen_3555 10 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 146308433 Common - phosphoribosylformylglycinamidine synthase Pmen_3414 233 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 146308813 Common - Peptidoglycan glycosyltransferase Pmen_3798 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 146307826 Common - response regulator receiver protein Pmen_2804 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 146305468 Common - regulatory protein, LuxR Pmen_0429 74 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 146306224 Common - nucleotidyltransferase-like protein Pmen_1192 24 COG3541 COG3541, Predicted nucleotidyltransferase General function prediction only 146309089 Common - Na+/Pi-cotransporter Pmen_4075 60 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 146306912 Common - chorismate synthase Pmen_1882 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 146307893 Common - Lysine/ornithine N-monooxygenase-like protein Pmen_2871 52 COG3486 IucD, Lysine/ornithine N-monooxygenase Secondary metabolites biosynthesis, transport, and catabolism 146308216 Common - 3-hydroxyisobutyrate dehydrogenase Pmen_3196 172 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 146305324 Common - HemY domain protein Pmen_0283 47 COG3071 HemY, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 146307089 Common - extracellular solute-binding protein, family 5 Pmen_2061 163 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 146305944 Common gmhA phosphoheptose isomerase Pmen_0909 122 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 146307392 Common - luciferase family protein Pmen_2367 83 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 146305315 Common - hypothetical protein Pmen_0274 7 None None None 146306040 Common - hypothetical protein Pmen_1005 7 None None None 146305992 Common - Tfp pilus assembly protein PilE-like protein Pmen_0957 33 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 146309297 Common - glycosyl transferase, group 1 Pmen_4283 6 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 146306035 Common - pentapeptide repeat protein Pmen_1000 22 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 146307478 Common - selenophosphate synthetase Pmen_2455 132 COG0709 SelD, Selenophosphate synthase Amino acid transport and metabolism 146306432 Common - electron transport complex, RnfABCDGE type, G subunit Pmen_1400 58 COG4659 RnfG, Predicted NADH:ubiquinone oxidoreductase, subunit RnfG Energy production and conversion 146308716 Common - protein of unknown function DUF922 Pmen_3701 8 COG5661 COG5661, Predicted secreted Zn-dependent protease Posttranslational modification, protein turnover, chaperones 146308228 Common - NAD(P)H dehydrogenase (quinone) Pmen_3208 99 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 146307921 Common - magnesium transporter Pmen_2899 174 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 146309080 Common - helix-turn-helix- domain containing protein, AraC type Pmen_4066 56 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 146306049 Common - Paraquat-inducible protein A Pmen_1014 56 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 146309339 Common - Peroxidase Pmen_4325 208 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 146306270 Common - Pirin domain protein domain protein Pmen_1238 138 COG1741 COG1741, Pirin-related protein General function prediction only 146305130 Common - ImpA domain protein Pmen_0089 31 COG3515 COG3515, Uncharacterized protein conserved in bacteria Function unknown 146306316 Common - beta-lactamase domain protein Pmen_1284 129 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 146308247 Common - Lysine exporter protein (LYSE/YGGA) Pmen_3227 103 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 146307652 Common - transcriptional regulator, MarR family Pmen_2629 131 COG1846 MarR, Transcriptional regulators Transcription 146308723 Common - hypothetical protein Pmen_3708 9 None None None 146307848 Common fliE flagellar hook-basal body protein FliE Pmen_2826 88 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 146307761 Common - N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase Pmen_2739 221 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 146305045 Common recF recombination protein F Pmen_0003 166 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 146306766 Common - (p)ppGpp synthetase I, SpoT/RelA Pmen_1735 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 146306975 Common - 40-residue YVTN family beta-propeller repeat protein Pmen_1947 86 COG3391 COG3391, Uncharacterized conserved protein Function unknown 146306091 Common lolB outer membrane lipoprotein LolB Pmen_1057 54 COG3017 LolB, Outer membrane lipoprotein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 146305052 Common - CDP-alcohol phosphatidyltransferase Pmen_0010 30 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 146306325 Common - oxidoreductase FAD/NAD(P)-binding domain protein Pmen_1293 108 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 146306165 Common - YceI family protein Pmen_1131 11 COG2353 COG2353, Uncharacterized conserved protein Function unknown 146306392 Common - hypothetical protein Pmen_1360 46 COG3665 COG3665, Uncharacterized conserved protein Function unknown 146308362 Common - ABC transporter related Pmen_3343 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 146305358 Common - secretion protein HlyD family protein Pmen_0317 101 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 146305579 Common - type IV pilus assembly protein PilM Pmen_0542 79 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 146305301 Common - ammonium transporter Pmen_0260 203 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 146308963 Pathogen - hypothetical protein Pmen_3949 1 None None None 146305937 Common rpsI 30S ribosomal protein S9 Pmen_0902 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 146307466 Common - TatD-related deoxyribonuclease Pmen_2443 225 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 146309390 Common radC DNA repair protein RadC Pmen_4376 179 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 146306339 Common - ABC transporter related Pmen_1307 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 146308666 Common - beta-lactamase domain protein Pmen_3651 215 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 146307782 Common - ureidoglycolate hydrolase Pmen_2760 35 COG3194 DAL3, Ureidoglycolate hydrolase Nucleotide transport and metabolism 146305513 Common - HI0933 family protein Pmen_0476 141 COG2081 COG2081, Predicted flavoproteins General function prediction only 146308599 Common - hypothetical protein Pmen_3584 236 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 146307885 Common - Taurine catabolism dioxygenase TauD/TfdA Pmen_2863 23 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 146308176 Common - transcriptional regulator, LysR family Pmen_3156 180 COG0583 LysR, Transcriptional regulator Transcription 146305224 Common - phosphate uptake regulator, PhoU Pmen_0183 194 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 146308979 Common - hypothetical protein Pmen_3965 4 None None None 146305424 Common - hypothetical protein Pmen_0384 3 None None None 146306028 Common - periplasmic binding protein Pmen_0993 127 COG4558 ChuT, ABC-type hemin transport system, periplasmic component Inorganic ion transport and metabolism 146307493 Common - 3-oxoacyl-(acyl carrier protein) synthase I Pmen_2470 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 146309051 Common - protein of unknown function DUF323 Pmen_4037 98 COG1262 COG1262, Uncharacterized conserved protein Function unknown 146308636 Common - carbamoyl phosphate synthase small subunit Pmen_3621 234 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 146306732 Common - methyl-accepting chemotaxis sensory transducer Pmen_1701 143 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146308698 Common - Polyprenyl synthetase Pmen_3683 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 146306795 Common - lipase chaperone Pmen_1764 12 COG5380 LimK, Lipase chaperone Posttranslational modification, protein turnover, chaperones 146306657 Common - fatty acid/phospholipid synthesis protein Pmen_1626 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 146306587 Common - DoxX family protein Pmen_1556 7 COG2259 COG2259, Predicted membrane protein Function unknown 146308996 Common - helix-turn-helix domain protein Pmen_3982 7 COG1709 COG1709, Predicted transcriptional regulator Transcription 146306423 Common - ribonuclease T Pmen_1391 64 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 146309514 Common - ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components-like protein Pmen_4500 62 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 146308357 Common - uncharacterised conserved protein UCP025560 Pmen_3338 26 COG3784 COG3784, Uncharacterized protein conserved in bacteria Function unknown 146306053 Common - short chain dehydrogenase Pmen_1018 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 146306664 Common - dTMP kinase Pmen_1633 227 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 146306988 Common - hypothetical protein Pmen_1960 22 COG5501 COG5501, Predicted secreted protein Function unknown 146309581 Common - TonB-dependent siderophore receptor Pmen_4567 105 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 146307917 Common - AraC-type transcriptional regulator domain protein Pmen_2895 134 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 146307024 Common - integral membrane sensor signal transduction histidine kinase Pmen_1996 173 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146307206 Common - RND efflux system, outer membrane lipoprotein, NodT family Pmen_2179 109 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 146308295 Common - hypothetical protein Pmen_3275 4 None None None 146305520 Common - transcriptional regulator BetI Pmen_0483 55 COG1309 AcrR, Transcriptional regulator Transcription 146307455 Common - Redoxin domain protein Pmen_2432 88 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 146309034 Pathogen - hypothetical protein Pmen_4020 1 None None None 146306002 Common - hypothetical protein Pmen_0967 18 None None None 146308165 Common - Bile acid:sodium symporter Pmen_3145 80 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 146307809 Common - cytochrome c-type biogenesis protein CcmE Pmen_2787 94 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 146306332 Common motB flagellar motor protein MotB Pmen_1300 96 COG1360 MotB, Flagellar motor protein Cell motility and secretion 146308991 Common - hypothetical protein Pmen_3977 1 None None None 146306009 Common - glycosyl transferase, group 1 Pmen_0974 192 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 146309460 Common - TRAP transporter solute receptor, TAXI family Pmen_4446 84 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 146307662 Common - acyl-CoA dehydrogenase domain protein Pmen_2640 160 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 146307033 Common - NADH:flavin oxidoreductase/NADH oxidase Pmen_2005 176 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 146309380 Common - glutamine synthetase, catalytic region Pmen_4366 229 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 146306654 Common - Maf-like protein Pmen_1623 192 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 146305199 Common - DSBA oxidoreductase Pmen_0158 66 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 146307066 Common ampC beta-lactamase Pmen_2038 109 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 146306105 Common - Deoxyribodipyrimidine photo-lyase Pmen_1071 138 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 146309278 Common - hypothetical protein Pmen_4264 5 COG1475 Spo0J, Predicted transcriptional regulators Transcription 146306124 Common - ABC transporter related Pmen_1090 249 COG4598 HisP, ABC-type histidine transport system, ATPase component Amino acid transport and metabolism 146307431 Common - protein of unknown function DUF839 Pmen_2408 72 COG3211 PhoX, Predicted phosphatase General function prediction only 146306570 Common - hypothetical protein Pmen_1539 3 None None None 146308795 Common - PhoH family protein Pmen_3780 198 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 146306382 Common - Deoxyribonuclease I Pmen_1350 30 COG2356 EndA, Endonuclease I DNA replication, recombination, and repair 146305211 Common - MCP methyltransferase, CheR-type Pmen_0170 149 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 146308839 Common - hypothetical protein Pmen_3824 7 None None None 146309068 Common - transcriptional regulator, LysR family Pmen_4054 140 COG0583 LysR, Transcriptional regulator Transcription 146309120 Pathogen - hypothetical protein Pmen_4106 1 None None None 146307290 Common - membrane protein-like protein Pmen_2265 19 COG4244 COG4244, Predicted membrane protein Function unknown 146306341 Common - hypothetical protein Pmen_1309 112 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 146307197 Common - hypothetical protein Pmen_2170 23 None None None 146305547 Common - hypothetical protein Pmen_0510 7 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 146305277 Common - protein of unknown function DUF861, cupin_3 Pmen_0236 33 COG3450 COG3450, Predicted enzyme of the cupin superfamily General function prediction only 146305924 Common - protein of unknown function DUF34 Pmen_0889 119 COG0327 COG0327, Uncharacterized conserved protein Function unknown 146309571 Common - hypothetical protein Pmen_4557 9 None None None 146309303 Common - dTDP-glucose 4,6-dehydratase Pmen_4289 231 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 146307142 Pathogen - hypothetical protein Pmen_2114 1 COG5137 COG5137, Histone chaperone involved in gene silencing Transcription / Chromatin structure and dynamics 146309548 Common - hypothetical protein Pmen_4534 1 None None None 146307403 Common - DsrC family protein Pmen_2380 48 COG2920 DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit Inorganic ion transport and metabolism 146309287 Common - hypothetical protein Pmen_4273 14 None None None 146305541 Common - protein of unknown function UPF0153 Pmen_0504 8 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 146306579 Common - transposase IS66 Pmen_1548 67 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 146308528 Common - serine O-acetyltransferase Pmen_3513 193 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 146306151 Common - NAD-dependent epimerase/dehydratase Pmen_1117 224 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 146308705 Common - hypothetical protein Pmen_3690 1 None None None 146306217 Common - hypothetical protein Pmen_1185 7 None None None 146308893 Common - peptidase M14, carboxypeptidase A Pmen_3879 12 COG2866 COG2866, Predicted carboxypeptidase Amino acid transport and metabolism 146305155 Common - hypothetical protein Pmen_0114 5 None None None 146309428 Common - ATPase, FliI/YscN family Pmen_4414 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 146305088 Common - type III secretion protein, HrpO family Pmen_0047 12 COG4794 EscS, Type III secretory pathway, component EscS Intracellular trafficking and secretion 146305963 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase Pmen_0928 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 146305716 Common - hypothetical protein Pmen_0681 9 None None None 146305438 Common - pyrimidine regulatory protein PyrR Pmen_0398 109 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 146307771 Common - regulatory protein GntR, HTH Pmen_2749 102 COG1802 GntR, Transcriptional regulators Transcription 146308236 Common - Ku domain protein Pmen_3216 63 COG1273 COG1273, Uncharacterized conserved protein Function unknown 146308023 Pathogen - membrane protein-like protein Pmen_3001 1 COG5393 COG5393, Predicted membrane protein Function unknown 146307525 Common - dihydrolipoamide acetyltransferase Pmen_2502 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 146308087 Common - succinyl-diaminopimelate desuccinylase Pmen_3066 190 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 146306825 Common - permease for cytosine/purine, uracil, thiamine, allantoin Pmen_1794 78 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 146309404 Common - (p)ppGpp synthetase I, SpoT/RelA Pmen_4390 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 146306623 Common - hypothetical protein Pmen_1592 3 None None None 146306513 Common - putative methyltransferase Pmen_1481 56 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 146306804 Common - ribonuclease D Pmen_1773 116 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 146306158 Common - UspA domain protein Pmen_1124 82 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 146305097 Common - Peptidoglycan-binding LysM Pmen_0056 46 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 146305538 Common - 3-hydroxybutyryl-CoA dehydrogenase Pmen_0501 157 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 146309163 Common - twitching motility protein Pmen_4149 215 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 146307433 Pathogen - hypothetical protein Pmen_2410 1 None None None 146308121 Common - beta-lactamase domain protein Pmen_3100 41 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 146308390 Common - peptide chain release factor 2 Pmen_3371 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 146305704 Common - fatty acid desaturase Pmen_0669 24 COG3239 DesA, Fatty acid desaturase Lipid metabolism 146305800 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Pmen_0765 197 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 146305413 Common - protein of unknown function DUF140 Pmen_0373 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 146307080 Common - ATP-dependent protease La Pmen_2052 214 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 146309595 Common - TonB-dependent receptor Pmen_4581 100 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 146307275 Common - phage integrase family protein Pmen_2249 48 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 146308318 Common - uncharacterised conserved protein UCP028101 Pmen_3298 24 COG3490 COG3490, Uncharacterized protein conserved in bacteria Function unknown 146307166 Common - peptidase M48, Ste24p Pmen_2139 83 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 146309316 Common - hypothetical protein Pmen_4302 25 None None None 146307952 Common - protein of unknown function DUF58 Pmen_2930 83 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 146305482 Pathogen - hypothetical protein Pmen_0445 1 None None None 146306702 Common - hypothetical protein Pmen_1671 9 None None None 146305440 Common - hypothetical protein Pmen_0400 129 COG1678 COG1678, Putative transcriptional regulator Transcription 146305100 Common - Alcohol dehydrogenase, zinc-binding domain protein Pmen_0059 176 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 146305261 Common - Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation)-like protein Pmen_0220 47 COG2843 PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) Cell envelope biogenesis, outer membrane 146307421 Common - NUDIX hydrolase Pmen_2398 46 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 146306140 Common - carbamate kinase Pmen_1106 65 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 146306568 Pathogen - hypothetical protein Pmen_1537 1 None None None 146309071 Common - transcriptional regulator, TetR family Pmen_4057 101 COG1309 AcrR, Transcriptional regulator Transcription 146306857 Common - potassium uptake protein, TrkH family Pmen_1826 134 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 146307078 Common clpP ATP-dependent Clp protease proteolytic subunit Pmen_2050 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 146307578 Common - hypothetical protein Pmen_2555 1 None None None 146307725 Common - hypothetical protein Pmen_2703 5 None None None 146308079 Common - arsenate reductase and related Pmen_3058 108 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 146306555 Common - hypothetical protein Pmen_1524 1 None None None 146308631 Common - ribosomal RNA methyltransferase RrmJ/FtsJ Pmen_3616 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 146308927 Common - 30S ribosomal protein S7 Pmen_3913 249 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 146307418 Common - putative cold-shock DNA-binding domain protein Pmen_2395 180 COG1278 CspC, Cold shock proteins Transcription 146308535 Common tgt queuine tRNA-ribosyltransferase Pmen_3520 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 146309267 Common - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase Pmen_4253 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 146306983 Common - hypothetical protein Pmen_1955 9 COG4244 COG4244, Predicted membrane protein Function unknown 146306389 Common - diguanylate cyclase Pmen_1357 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 146306815 Common - glutamine amidotransferase, class-II Pmen_1784 72 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 146307071 Common - ABC transporter related Pmen_2043 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 146308350 Common - alpha/beta hydrolase fold Pmen_3331 113 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 146307366 Common - UDP-galactopyranose mutase Pmen_2341 60 COG0562 Glf, UDP-galactopyranose mutase Cell envelope biogenesis, outer membrane 146305379 Common - transcriptional regulator, TetR family Pmen_0339 6 COG1309 AcrR, Transcriptional regulator Transcription 146306935 Common - hypothetical protein Pmen_1906 9 None None None 146308285 Common - hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit Pmen_3265 148 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 146305056 Common glyQ glycyl-tRNA synthetase subunit alpha Pmen_0014 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 146305043 Common dnaA chromosomal replication initiation protein Pmen_0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 146306924 Common - DinB family protein Pmen_1895 36 COG2318 DinB, Uncharacterized protein conserved in bacteria Function unknown 146306343 Common - glyceraldehyde-3-phosphate dehydrogenase, type I Pmen_1311 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 146305970 Common - ATP--cobalamin adenosyltransferase Pmen_0935 128 COG2096 COG2096, Uncharacterized conserved protein Function unknown 146309616 Common - transcriptional regulator, DeoR family Pmen_4603 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 146305218 Common - transport-associated Pmen_0177 76 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 146306694 Common - dihydrodipicolinate synthase Pmen_1663 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 146309205 Common coaD phosphopantetheine adenylyltransferase Pmen_4191 209 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 146307075 Common - extracellular solute-binding protein, family 1 Pmen_2047 39 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 146305137 Common - protein of unknown function DUF1305 Pmen_0096 45 COG3520 COG3520, Uncharacterized protein conserved in bacteria Function unknown 146309009 Pathogen - hypothetical protein Pmen_3995 1 None None None 146306528 Common - acyl-CoA synthetase Pmen_1496 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 146306031 Common - protein of unknown function DUF399 Pmen_0996 30 COG3016 PhuW, Uncharacterized iron-regulated protein Function unknown 146305051 Common - alpha/beta hydrolase fold Pmen_0009 59 COG2267 PldB, Lysophospholipase Lipid metabolism 146305085 Pathogen - hypothetical protein Pmen_0044 2 None None None 146306418 Common - inner-membrane translocator Pmen_1386 159 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 146307737 Common - acetyl-CoA carboxylase subunit beta Pmen_2715 219 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 146306640 Common - lipoprotein releasing system, transmembrane protein, LolC/E family Pmen_1609 188 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 146308340 Common - ATPase associated with various cellular activities, AAA_3 Pmen_3320 178 COG0714 COG0714, MoxR-like ATPases General function prediction only 146305834 Common - ABC transporter related Pmen_0799 241 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 146307107 Common - transcriptional regulator, GntR family Pmen_2079 141 COG1802 GntR, Transcriptional regulators Transcription 146306911 Common - Lysophospholipase-like protein Pmen_1881 30 COG2267 PldB, Lysophospholipase Lipid metabolism 146306362 Common - binding-protein-dependent transport systems inner membrane component Pmen_1330 181 COG4132 COG4132, ABC-type uncharacterized transport system, permease component General function prediction only 146305373 Common - regulatory protein, ArsR Pmen_0333 167 COG0640 ArsR, Predicted transcriptional regulators Transcription 146305648 Common - small multidrug resistance protein Pmen_0613 131 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 146308373 Common - Extensin family protein Pmen_3354 37 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 146308347 Common - transcriptional regulator, AraC family Pmen_3327 154 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 146307763 Common - isochorismatase hydrolase Pmen_2741 70 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 146308283 Common - hypothetical protein Pmen_3263 52 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 146307292 Common - Cytochrome-c oxidase Pmen_2267 175 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 146309000 Common - hypothetical protein Pmen_3986 1 None None None 146306613 Common - protein of unknown function DUF1653 Pmen_1582 36 COG4728 COG4728, Uncharacterized protein conserved in bacteria Function unknown 146306038 Common - Tetratricopeptide TPR_4 Pmen_1003 9 COG3071 HemY, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 146309138 Common - metal dependent phosphohydrolase Pmen_4124 123 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 146309487 Common - xylulokinase Pmen_4473 183 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 146305683 Common rplI 50S ribosomal protein L9 Pmen_0648 199 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 146309230 Common - protein of unknown function DUF833 Pmen_4216 49 COG3332 COG3332, Uncharacterized conserved protein Function unknown 146306676 Common - peptidase S8 and S53, subtilisin, kexin, sedolisin Pmen_1645 11 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 146308015 Common - DNA replication initiation factor Pmen_2993 126 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 146308103 Pathogen - hypothetical protein Pmen_3082 1 None None None 146308626 Common secG preprotein translocase subunit SecG Pmen_3611 7 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 146305305 Common xerC site-specific tyrosine recombinase XerC Pmen_0264 220 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 146305517 Common - major facilitator superfamily MFS_1 Pmen_0480 194 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 146306761 Common - multi-sensor hybrid histidine kinase Pmen_1730 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146307889 Common - TonB-dependent siderophore receptor Pmen_2867 123 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 146305398 Common - RNA binding S1 domain protein Pmen_0358 183 COG2183 Tex, Transcriptional accessory protein Transcription 146305610 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) Pmen_0573 185 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 146308111 Common - hypothetical protein Pmen_3090 2 None None None 146305470 Common - transposase IS66 Pmen_0431 67 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 146308821 Common - phosphoesterase, PA-phosphatase related Pmen_3806 114 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 146308710 Common - beta alanine--pyruvate transaminase Pmen_3695 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 146308890 Common - single-strand binding protein Pmen_3876 211 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 146307530 Common - succinate dehydrogenase, cytochrome b subunit Pmen_2507 90 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 146305181 Common - Auxin Efflux Carrier Pmen_0140 121 COG0679 COG0679, Predicted permeases General function prediction only 146307381 Common - sodium/hydrogen exchanger Pmen_2356 29 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 146307136 Common - enoyl-CoA hydratase Pmen_2108 102 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 146307441 Common - NADH dehydrogenase subunit H Pmen_2418 186 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 146308114 Common - malate:quinone oxidoreductase Pmen_3093 57 COG0579 COG0579, Predicted dehydrogenase General function prediction only 146306506 Common - hypothetical protein Pmen_1474 5 None None None 146308464 Common - extracellular solute-binding protein, family 1 Pmen_3447 68 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 146307849 Common - two component, sigma54 specific, transcriptional regulator, Fis family Pmen_2827 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 146308083 Common - protein of unknown function DUF1456 Pmen_3062 31 COG4807 COG4807, Uncharacterized protein conserved in bacteria Function unknown 146306286 Common - Methyltransferase type 12 Pmen_1254 78 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 146305643 Common - NUDIX hydrolase Pmen_0608 84 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 146309098 Common bioD dithiobiotin synthetase Pmen_4084 132 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 146305169 Common aspA aspartate ammonia-lyase Pmen_0128 225 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 146305619 Common - lipopolysaccharide kinase Pmen_0582 10 None None None 146309608 Common - iron-containing alcohol dehydrogenase Pmen_4594 175 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 146306488 Common - hypothetical protein Pmen_1456 1 None None None 146305844 Common - 3-beta hydroxysteroid dehydrogenase/isomerase Pmen_0809 71 COG2910 COG2910, Putative NADH-flavin reductase General function prediction only 146307639 Common - adenine phosphoribosyltransferase Pmen_2616 183 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 146309224 Common - glycerophosphoryl diester phosphodiesterase Pmen_4210 131 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 146305241 Common - protein of unknown function DUF336 Pmen_0200 78 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 146305658 Common - HDOD Pmen_0623 4 None None None 146308364 Common - glycerol kinase Pmen_3345 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 146305628 Common - Acetyltransferase (isoleucine patch superfamily)-like protein Pmen_0591 68 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 146309624 Common - ATP synthase F0, B subunit Pmen_4611 155 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 146308602 Common - hypothetical protein Pmen_3587 4 None None None 146306302 Common ruvC Holliday junction resolvase Pmen_1270 194 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 146306131 Common - outer membrane porin Pmen_1097 11 None None None 146307111 Common - putative AcnD-accessory protein PrpF Pmen_2083 55 COG2828 COG2828, Uncharacterized protein conserved in bacteria Function unknown 146305746 Common - MJ0042 family finger-like protein Pmen_0711 16 None None None 146306508 Common era GTP-binding protein Era Pmen_1476 221 COG1159 Era, GTPase General function prediction only 146308354 Common - transcriptional regulator, XRE family Pmen_3335 19 COG1476 COG1476, Predicted transcriptional regulators Transcription 146305556 Common hisE phosphoribosyl-ATP pyrophosphatase Pmen_0519 179 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 146305845 Common - transcriptional regulator, LysR family Pmen_0810 127 COG0583 LysR, Transcriptional regulator Transcription 146307378 Common - UTP-glucose-1-phosphate uridylyltransferase GalU Pmen_2353 233 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 146308875 Common - thioredoxin Pmen_3861 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 146306072 Pathogen - hypothetical protein Pmen_1037 1 None None None 146306010 Common - hypothetical protein Pmen_0975 13 None None None 146305554 Common - twin-arginine translocation protein, TatB subunit Pmen_0517 39 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 146306164 Common - hypothetical protein Pmen_1130 1 None None None 146307059 Common - gamma-carboxygeranoyl-CoA hydratase Pmen_2031 173 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 146309412 Common - putative signal transduction protein Pmen_4398 54 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 146309505 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Pmen_4491 62 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 146308506 Common - peptidase M23B Pmen_3491 188 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 146309424 Common - Chorismate lyase Pmen_4410 48 COG3161 UbiC, 4-hydroxybenzoate synthetase (chorismate lyase) Coenzyme metabolism 146307877 Common - FlgN family protein Pmen_2855 3 COG3418 COG3418, Flagellar biosynthesis/type III secretory pathway chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 146307794 Common - Hydroxypyruvate reductase Pmen_2772 86 COG2379 GckA, Putative glycerate kinase Carbohydrate transport and metabolism 146308905 Common rpmD 50S ribosomal protein L30 Pmen_3891 87 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 146307797 Common - DNA topoisomerase Pmen_2775 45 COG3569 COG3569, Topoisomerase IB DNA replication, recombination, and repair 146308249 Common - protein of unknown function DUF344 Pmen_3229 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 146309458 Common - Xanthine/uracil/vitamin C permease Pmen_4444 28 COG2252 COG2252, Permeases General function prediction only 146306592 Common - Pirin domain protein domain protein Pmen_1561 147 COG1741 COG1741, Pirin-related protein General function prediction only 146308670 Common - alpha/beta hydrolase fold Pmen_3655 173 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 146305863 Common - protein of unknown function, zinc metallopeptidase putative Pmen_0828 86 COG2321 COG2321, Predicted metalloprotease General function prediction only 146307050 Common - transcriptional regulator, LysR family Pmen_2022 192 COG0583 LysR, Transcriptional regulator Transcription 146305120 Common - hypothetical protein Pmen_0079 7 None None None 146305527 Common - transcriptional regulator, AraC family Pmen_0490 147 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 146309152 Common - GTP-binding protein TypA Pmen_4138 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 146308882 Common - TonB family protein Pmen_3868 14 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 146306617 Common - SOS-response cell division inhibitor blocks FtsZ ring formation-like protein Pmen_1586 7 COG5404 SulA, SOS-response cell division inhibitor, blocks FtsZ ring formation Cell division and chromosome partitioning 146308726 Common - transcriptional regulator, LysR family Pmen_3711 109 COG0583 LysR, Transcriptional regulator Transcription 146307360 Common - 3-oxoacyl-(acyl carrier protein) synthase Pmen_2335 10 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 146309177 Common - hypothetical protein Pmen_4163 1 None None None 146306062 Common - hypothetical protein Pmen_1027 4 None None None 146308609 Common pgi glucose-6-phosphate isomerase Pmen_3594 199 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 146307105 Common - hypothetical protein Pmen_2077 19 None None None 146305561 Common - putative polyhydroxyalkanoic acid system protein Pmen_0524 11 None None None 146309519 Common - NLPA lipoprotein Pmen_4505 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 146309382 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Pmen_4368 31 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 146306836 Pathogen - hypothetical protein Pmen_1805 1 None None None 146307967 Common - hypothetical protein Pmen_2945 18 COG3782 COG3782, Uncharacterized protein conserved in bacteria Function unknown 146306728 Common - homogentisate 1,2-dioxygenase Pmen_1697 53 COG3508 HmgA, Homogentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 146308864 Common - hypothetical protein Pmen_3850 6 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146307822 Common motC flagellar motor protein Pmen_2800 123 COG1291 MotA, Flagellar motor component Cell motility and secretion 146306797 Common - two component transcriptional regulator, LuxR family Pmen_1766 122 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 146306095 Common - modification methylase, HemK family Pmen_1061 210 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 146309234 Common - integral membrane protein-like protein Pmen_4220 1 COG5528 COG5528, Predicted integral membrane protein Function unknown 146309117 Common - TonB-dependent siderophore receptor Pmen_4103 115 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 146306247 Common - 5-dehydro-4-deoxyglucarate dehydratase Pmen_1215 222 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 146306291 Common - thioesterase superfamily protein Pmen_1259 37 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 146308007 Common - type IV pilus assembly PilZ Pmen_2985 4 None None None 146307444 Common - NADH dehydrogenase subunit K Pmen_2421 163 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 146305178 Common - GCN5-related N-acetyltransferase Pmen_0137 72 COG0456 RimI, Acetyltransferases General function prediction only 146307318 Common - glycogen branching enzyme Pmen_2293 148 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 146308423 Common - protein of unknown function DUF21 Pmen_3404 219 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 146306184 Common - extracellular solute-binding protein, family 1 Pmen_1150 70 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 146306021 Common - hypothetical protein Pmen_0986 2 None None None 146308005 Common - periplasmic nitrate (or nitrite) reductase c-type cytochrome, NapC/NirT family Pmen_2983 45 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 146306215 Common - Phage-related protein predicted endonuclease-like protein Pmen_1183 22 COG5377 COG5377, Phage-related protein, predicted endonuclease DNA replication, recombination, and repair 146307684 Common - isochorismatase hydrolase Pmen_2662 80 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 146305723 Common - type II secretion system protein Pmen_0688 27 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 146305092 Common - Tetratricopeptide TPR_2 repeat protein Pmen_0051 11 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 146307726 Common - extracellular solute-binding protein, family 3 Pmen_2704 27 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146305499 Common - fructose-1,6-bisphosphate aldolase Pmen_0462 176 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 146306787 Common cobU adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase Pmen_1756 125 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 146306411 Common - thioesterase superfamily protein Pmen_1379 54 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 146307719 Common - hypothetical protein Pmen_2697 1 COG5373 COG5373, Predicted membrane protein Function unknown 146308391 Common - Autotransporter beta- domain protein Pmen_3372 11 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 146305146 Common - protein phosphatase 2C domain protein Pmen_0105 136 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 146307561 Common - regulatory protein, LuxR Pmen_2538 130 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 146308205 Common - diguanylate cyclase Pmen_3185 172 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 146305878 Common - peptidase M24 Pmen_0843 234 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 146307575 Common - phospho-2-dehydro-3-heoxyheptonate aldolase Pmen_2552 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 146308779 Common - acyl-CoA dehydrogenase domain protein Pmen_3764 134 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 146307995 Common - hypothetical protein Pmen_2973 8 COG4430 COG4430, Uncharacterized protein conserved in bacteria Function unknown 146305726 Common - Hemerythrin HHE cation binding domain protein Pmen_0691 16 None None None 146306460 Pathogen - monovalent cation/proton antiporter, MnhG/PhaG subunit Pmen_1428 1 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 146306747 Common - protein of unknown function DUF1214 Pmen_1716 42 COG5361 COG5361, Uncharacterized conserved protein Function unknown 146306089 Common - ribose-phosphate pyrophosphokinase Pmen_1055 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 146308325 Common - GntR domain protein Pmen_3305 137 COG2186 FadR, Transcriptional regulators Transcription 146305361 Common - hypothetical protein Pmen_0320 1 None None None 146307753 Common - hypothetical protein Pmen_2731 27 COG2267 PldB, Lysophospholipase Lipid metabolism 146308398 Common - Allophanate hydrolase subunit 1 Pmen_3379 98 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 146309554 Common - protein of unknown function DUF37 Pmen_4540 179 COG0759 COG0759, Uncharacterized conserved protein Function unknown 146308801 Common leuS leucyl-tRNA synthetase Pmen_3786 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 146307126 Common - nitrite transporter Pmen_2098 96 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 146309294 Common - glycosyl transferase, group 1 Pmen_4280 101 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 146308854 Common - exodeoxyribonuclease VII, small subunit Pmen_3840 9 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 146307239 Common - heavy metal efflux pump, CzcA family Pmen_2212 177 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 146305599 Common - 2-nitropropane dioxygenase, NPD Pmen_0562 137 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 146308274 Common - amino acid permease-associated region Pmen_3254 178 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 146306298 Common - short-chain dehydrogenase/reductase SDR Pmen_1266 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 146305319 Common - histidine kinase internal region Pmen_0278 101 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 146305592 Common - hypothetical protein Pmen_0555 11 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 146308455 Common - alpha/beta hydrolase fold Pmen_3438 189 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 146305782 Common - cytochrome d ubiquinol oxidase, subunit II Pmen_0747 147 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 146307954 Common - von Willebrand factor, type A Pmen_2932 84 COG2304 COG2304, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 146305792 Common - type IV pilus assembly PilZ Pmen_0757 19 None None None 146308038 Common - CinA domain protein Pmen_3016 192 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 146308138 Common - binding-protein-dependent transport systems inner membrane component Pmen_3118 131 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 146307710 Common - transcriptional regulator, TetR family Pmen_2688 111 COG1309 AcrR, Transcriptional regulator Transcription 146308231 Common - hypothetical protein Pmen_3211 41 None None None 146309187 Common - protein of unknown function DUF214 Pmen_4173 101 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 146307904 Common phnK phosphonates transport ATP-binding protein Pmen_2882 247 COG4107 PhnK, ABC-type phosphonate transport system, ATPase component Inorganic ion transport and metabolism 146306277 Common - major facilitator superfamily MFS_1 Pmen_1245 36 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 146308487 Common - formyltetrahydrofolate deformylase Pmen_3470 216 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 146305759 Common - hypothetical protein Pmen_0724 22 COG5345 COG5345, Uncharacterized protein conserved in bacteria Function unknown 146306846 Common - Peptidoglycan-binding LysM Pmen_1815 30 COG3170 FimV, Tfp pilus assembly protein FimV Cell motility and secretion / Intracellular trafficking and secretion 146307232 Common - transcriptional regulator, LysR family Pmen_2205 185 COG0583 LysR, Transcriptional regulator Transcription 146307630 Common - cytochrome c oxidase, cbb3-type, subunit III Pmen_2607 84 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 146306264 Common - pseudouridine synthase Pmen_1232 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 146309149 Common - outer membrane autotransporter barrel domain Pmen_4135 29 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 146307062 Common - putative transcriptional regulator, MerR family Pmen_2034 116 COG0789 SoxR, Predicted transcriptional regulators Transcription 146308529 Common - RNA methyltransferase, TrmH family, group 1 Pmen_3514 159 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 146307288 Common - peptidase S14, ClpP Pmen_2263 2 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 146307467 Common - methyl-accepting chemotaxis sensory transducer Pmen_2444 148 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146309602 Common - cobalamin (vitamin B12) biosynthesis CbiG protein Pmen_4588 24 COG2073 CbiG, Cobalamin biosynthesis protein CbiG Coenzyme metabolism 146309090 Pathogen - hypothetical protein Pmen_4076 1 None None None 146308840 Common - aromatic acid decarboxylase Pmen_3825 152 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 146308926 Common - elongation factor G Pmen_3912 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 146309563 Common - hypothetical protein Pmen_4549 2 None None None 146306447 Common - hypothetical protein Pmen_1415 4 None None None 146306449 Common - Water Stress and Hypersensitive response Pmen_1417 8 COG5608 COG5608, Conserved secreted protein Function unknown 146307439 Common - NADH-quinone oxidoreductase, F subunit Pmen_2416 168 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 146305125 Common - integral membrane sensor signal transduction histidine kinase Pmen_0084 156 COG4564 COG4564, Signal transduction histidine kinase Signal transduction mechanisms 146306019 Common - hypothetical protein Pmen_0984 2 None None None 146305801 Common - hypothetical protein Pmen_0766 1 None None None 146307481 Common - hypothetical protein Pmen_2458 7 None None None 146308095 Pathogen - hypothetical protein Pmen_3074 1 None None None 146308737 Common - histone deacetylase superfamily Pmen_3722 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 146306906 Common - hypothetical protein Pmen_1876 51 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 146305508 Common - protein of unknown function DUF107 Pmen_0471 65 COG1030 NfeD, Membrane-bound serine protease (ClpP class) Posttranslational modification, protein turnover, chaperones 146309475 Common - Oligopeptidase A Pmen_4461 123 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 146306395 Common - hypothetical protein Pmen_1363 3 None None None 146305771 Common - protein of unknown function DUF606 Pmen_0736 62 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 146306069 Common moaC molybdenum cofactor biosynthesis protein C Pmen_1034 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 146308976 Common - hypothetical protein Pmen_3962 25 None None None 146306718 Pathogen - hypothetical protein Pmen_1687 3 None None None 146306543 Common - ATP-dependent helicase HrpA Pmen_1511 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 146307014 Common - exodeoxyribonuclease V, beta subunit Pmen_1986 212 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 146308496 Common - phage transcriptional regulator, AlpA Pmen_3481 20 COG3311 AlpA, Predicted transcriptional regulator Transcription 146307354 Common - protein of unknown function DUF879 Pmen_2329 48 COG3519 COG3519, Uncharacterized protein conserved in bacteria Function unknown 146305288 Common dadX alanine racemase Pmen_0247 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 146309447 Common - NAD(P)(+) transhydrogenase (AB-specific) Pmen_4433 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 146306530 Common - protein of unknown function DUF6, transmembrane Pmen_1498 11 None None None 146307644 Common - short-chain dehydrogenase/reductase SDR Pmen_2621 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 146308171 Common - ribonucleotide-diphosphate reductase subunit alpha Pmen_3151 227 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 146305419 Common - 3-hydroxybutyryl-CoA epimerase Pmen_0379 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 146308617 Common - CsbD family protein Pmen_3602 54 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 146306481 Pathogen - hypothetical protein Pmen_1449 1 None None None 146307597 Common - UDP-2,3-diacylglucosamine hydrolase Pmen_2574 77 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 146306476 Common - cation antiporter Pmen_1444 77 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 146306178 Common - Antibiotic biosynthesis monooxygenase Pmen_1144 16 COG1359 COG1359, Uncharacterized conserved protein Function unknown 146305206 Common - N-acetylmuramoyl-L-alanine amidase, family 2 Pmen_0165 105 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 146307491 Common - integral membrane sensor hybrid histidine kinase Pmen_2468 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146307504 Common - hypothetical protein Pmen_2481 1 None None None 146309543 Common - hypothetical protein Pmen_4529 6 None None None 146307028 Common - methyl-accepting chemotaxis sensory transducer Pmen_2000 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146308145 Common - hypothetical protein Pmen_3125 5 None None None 146305345 Common - polar amino acid ABC transporter, inner membrane subunit Pmen_0304 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 146307637 Common - hypothetical protein Pmen_2614 4 None None None 146307666 Common - hypothetical protein Pmen_2644 2 None None None 146306390 Common - biotin carboxylation domain protein Pmen_1358 229 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 146308132 Common phhA phenylalanine 4-monooxygenase Pmen_3112 45 COG3186 COG3186, Phenylalanine-4-hydroxylase Amino acid transport and metabolism 146309325 Common - multi-sensor signal transduction histidine kinase Pmen_4311 221 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 146308195 Common - protein of unknown function DUF1176 Pmen_3175 13 None None None 146309610 Common - ABC-type branched-chain amino acid transport systems periplasmic component-like protein Pmen_4596 111 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 146308887 Common - OmpW family protein Pmen_3873 68 COG3047 OmpW, Outer membrane protein W Cell envelope biogenesis, outer membrane 146307600 Common - protein of unknown function DUF1289 Pmen_2577 19 COG3313 COG3313, Predicted Fe-S protein General function prediction only 146308916 Common rplP 50S ribosomal protein L16 Pmen_3902 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 146305822 Common - 1-phosphofructokinase Pmen_0787 107 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 146305459 Common - YceI family protein Pmen_0419 118 COG2353 COG2353, Uncharacterized conserved protein Function unknown 146305853 Common - hypothetical protein Pmen_0818 1 None None None 146308302 Common - protein of unknown function DUF985 Pmen_3282 57 COG3542 COG3542, Uncharacterized conserved protein Function unknown 146306792 Common - major facilitator superfamily MFS_1 Pmen_1761 60 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 146308211 Common - Alcohol dehydrogenase GroES domain protein Pmen_3191 154 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 146306456 Common - protein of unknown function DUF1145 Pmen_1424 1 COG3776 COG3776, Predicted membrane protein Function unknown 146308745 Common - protein of unknown function DUF88 Pmen_3730 62 COG1432 COG1432, Uncharacterized conserved protein Function unknown 146305981 Common upp uracil phosphoribosyltransferase Pmen_0946 166 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 146306044 Common - ketol-acid reductoisomerase Pmen_1009 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 146307741 Common - aspartate-semialdehyde dehydrogenase Pmen_2719 172 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 146309244 Common - fumarylacetoacetate (FAA) hydrolase Pmen_4230 178 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 146308189 Common - Allergen V5/Tpx-1 family protein Pmen_3169 59 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 146309058 Common - TRAP dicarboxylate transporter, DctM subunit Pmen_4044 120 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 146308962 Common - protein of unknown function DUF159 Pmen_3948 107 COG2135 COG2135, Uncharacterized conserved protein Function unknown 146306740 Common - UDP-N-acetylglucosamine 2-epimerase Pmen_1709 153 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 146307607 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase Pmen_2584 153 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 146306964 Common - Nucleotidyltransferase/DNA polymerase involved in DNA repair-like protein Pmen_1935 61 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 146306416 Common livG leucine/isoleucine/valine transporter ATP-binding subunit Pmen_1384 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 146307674 Common - Sel1 domain protein repeat-containing protein Pmen_2652 108 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 146308324 Common - protein of unknown function DUF6, transmembrane Pmen_3304 3 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 146307628 Common - cytochrome c oxidase, cbb3-type, subunit II Pmen_2605 82 COG2993 CcoO, Cbb3-type cytochrome oxidase, cytochrome c subunit Energy production and conversion 146305697 Common - Glycerophosphodiester phosphodiesterase Pmen_0662 181 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 146309048 Common - hypothetical protein Pmen_4034 5 None None None 146308182 Common - hypothetical protein Pmen_3162 3 None None None 146305283 Common - FAD dependent oxidoreductase Pmen_0242 113 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 146306955 Common - thioesterase superfamily protein Pmen_1926 67 COG0824 FcbC, Predicted thioesterase General function prediction only 146306940 Common - integral membrane sensor hybrid histidine kinase Pmen_1911 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146309114 Common - hypothetical protein Pmen_4100 10 None None None 146307748 Common - heat shock protein Hsp20 Pmen_2726 67 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 146309109 Common - GCN5-related N-acetyltransferase Pmen_4095 53 COG0456 RimI, Acetyltransferases General function prediction only 146307924 Common - aspartate kinase Pmen_2902 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 146305463 Common - hypothetical protein Pmen_0423 8 None None None 146308254 Common - cytochrome B561 Pmen_3234 54 COG3038 CybB, Cytochrome B561 Energy production and conversion 146306200 Common - transcriptional regulator, LysR family Pmen_1167 40 COG0583 LysR, Transcriptional regulator Transcription 146307199 Common - nicotinamide mononucleotide transporter PnuC Pmen_2172 46 COG3201 PnuC, Nicotinamide mononucleotide transporter Coenzyme metabolism 146306589 Common - FAD linked oxidase domain protein Pmen_1558 176 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 146306850 Common - export-related chaperone CsaA Pmen_1819 101 COG0073 ARC1, EMAP domain General function prediction only 146306868 Common - tryptophanyl-tRNA synthetase Pmen_1837 233 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 146308043 Common - protein of unknown function DUF368 Pmen_3022 50 COG2035 COG2035, Predicted membrane protein Function unknown 146305600 Common - type I restriction-modification system, M subunit Pmen_0563 161 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 146305081 Pathogen - type III secretion apparatus protein, YscD/HrpQ family Pmen_0040 2 None None None 146307787 Common - hypothetical protein Pmen_2765 5 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146307527 Common sdhB succinate dehydrogenase iron-sulfur subunit Pmen_2504 207 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 146305762 Common - arginine decarboxylase Pmen_0727 92 COG1166 SpeA, Arginine decarboxylase (spermidine biosynthesis) Amino acid transport and metabolism 146309452 Common - hypothetical protein Pmen_4438 6 None None None 146306471 Common - Glycerate kinase Pmen_1439 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 146305502 Common - glucose sorbosone dehydrogenase Pmen_0465 117 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 146308435 Pathogen - hypothetical protein Pmen_3416 1 None None None 146305457 Common - regulatory protein, IclR Pmen_0417 119 COG1414 IclR, Transcriptional regulator Transcription 146305990 Common - peptidylprolyl isomerase, FKBP-type Pmen_0955 135 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 146309285 Common - polar amino acid ABC transporter, inner membrane subunit Pmen_4271 172 COG4215 ArtQ, ABC-type arginine transport system, permease component Amino acid transport and metabolism 146307810 Common - Heme exporter protein D (CcmD) Pmen_2788 11 COG3114 CcmD, Heme exporter protein D Intracellular trafficking and secretion 146305153 Common - protein of unknown function DUF1311 Pmen_0112 9 COG3755 COG3755, Uncharacterized protein conserved in bacteria Function unknown 146307170 Common - Spermidine synthase-like protein Pmen_2143 56 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 146305403 Common - alpha-L-glutamate ligase, RimK family Pmen_0363 156 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 146309494 Common - transcriptional regulator, LysR family Pmen_4480 189 COG0583 LysR, Transcriptional regulator Transcription 146305852 Common - hypothetical protein Pmen_0817 1 None None None 146307087 Common - binding-protein-dependent transport systems inner membrane component Pmen_2059 219 COG4174 COG4174, ABC-type uncharacterized transport system, permease component General function prediction only 146308806 Common - lipoyl synthase Pmen_3791 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 146305656 Common psd phosphatidylserine decarboxylase Pmen_0621 96 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 146308550 Common - putative SAM-dependent methyltransferase Pmen_3535 28 COG3129 COG3129, Predicted SAM-dependent methyltransferase General function prediction only 146308534 Common yajC preprotein translocase subunit YajC Pmen_3519 172 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 146308815 Common - iojap-like protein Pmen_3800 201 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 146305702 Common - transcriptional regulator, TetR family Pmen_0667 43 COG1309 AcrR, Transcriptional regulator Transcription 146308571 Common - transcriptional regulator, AraC family Pmen_3556 141 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 146305382 Common - Glutamate--putrescine ligase Pmen_0342 225 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 146307241 Common - outer membrane porin Pmen_2214 11 None None None 146307248 Common - hypothetical protein Pmen_2221 8 None None None 146308774 Common - CRISPR-associated protein, Cse2 family Pmen_3759 9 None None None 146305292 Common - xanthine phosphoribosyltransferase Pmen_0251 122 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 146307926 Common - Threonine aldolase Pmen_2904 97 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 146307839 Common - flagellar hook-length control protein Pmen_2817 44 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 146309135 Common - putative signal-transduction protein with CBS domains Pmen_4121 163 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 146308834 Common - acyl-CoA dehydrogenase domain protein Pmen_3819 149 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 146307506 Common - methyl-accepting chemotaxis sensory transducer Pmen_2483 135 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146308226 Common - transcriptional regulator, LysR family Pmen_3206 181 COG0583 LysR, Transcriptional regulator Transcription 146305690 Common - transglutaminase, N-terminal domain protein Pmen_0655 83 COG4196 COG4196, Uncharacterized protein conserved in bacteria Function unknown 146306046 Common - putative sulfite oxidase subunit YedY Pmen_1011 117 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 146307151 Common - hypothetical protein Pmen_2124 4 None None None 146305317 Common - hypothetical protein Pmen_0276 3 None None None 146307158 Common - transcriptional regulator, LysR family Pmen_2131 170 COG0583 LysR, Transcriptional regulator Transcription 146307831 Common flhB flagellar biosynthesis protein FlhB Pmen_2809 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 146309488 Common - PfkB domain protein Pmen_4474 150 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 146308153 Common malS periplasmic alpha-amylase precursor Pmen_3133 152 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 146305824 Common - hypothetical protein Pmen_0789 10 None None None 146308721 Common - adenosine deaminase Pmen_3706 102 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 146306985 Common - Pyrrolo-quinoline quinone Pmen_1957 73 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 146307986 Common - protein of unknown function DUF1282 Pmen_2964 24 None None None 146307997 Common - integral membrane sensor signal transduction histidine kinase Pmen_2975 199 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146308327 Common - hypothetical protein Pmen_3307 1 None None None 146308869 Common - bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein Pmen_3855 229 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 146309065 Common - agmatinase Pmen_4051 154 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 146306704 Common - hypothetical protein Pmen_1673 2 None None None 146308902 Common rpmJ 50S ribosomal protein L36 Pmen_3888 139 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 146307193 Common - hypothetical protein Pmen_2166 20 COG0753 KatE, Catalase Inorganic ion transport and metabolism 146306425 Common - OmpA/MotB domain protein Pmen_1393 41 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 146308341 Common - protein of unknown function DUF58 Pmen_3321 109 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 146306973 Common - ABC-2 type transporter Pmen_1945 54 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 146305387 Common - spermidine/putrescine ABC transporter ATPase subunit Pmen_0347 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 146306037 Common - penicillin-binding protein 1B Pmen_1002 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 146305244 Common - glycolate oxidase subunit GlcD Pmen_0203 200 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 146308036 Common recX recombination regulator RecX Pmen_3014 84 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 146305733 Common - ABC transporter related Pmen_0698 249 COG4674 COG4674, Uncharacterized ABC-type transport system, ATPase component General function prediction only 146308641 Common - DNA repair protein RecN Pmen_3626 200 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 146306353 Common - carboxyl-terminal protease Pmen_1321 182 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 146306914 Common - hypothetical protein Pmen_1884 28 COG1791 COG1791, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 146306789 Common - Phosphoglycerate mutase Pmen_1758 69 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 146305590 Common - Cobyrinic acid a,c-diamide synthase Pmen_0553 220 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 146307048 Common - hypothetical protein Pmen_2020 40 COG3002 COG3002, Uncharacterized protein conserved in bacteria Function unknown 146305222 Common - phosphate ABC transporter, inner membrane subunit PstA Pmen_0181 223 COG4985 COG4985, ABC-type phosphate transport system, auxiliary component Inorganic ion transport and metabolism 146306490 Common - outer membrane porin Pmen_1458 9 None None None 146306463 Common - NADH dehydrogenase (quinone) Pmen_1431 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 146307648 Common - short-chain dehydrogenase/reductase SDR Pmen_2625 136 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 146308845 Common - hypothetical protein Pmen_3830 15 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 146305961 Common - cell division protein FtsA Pmen_0926 192 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 146305073 Pathogen - hypothetical protein Pmen_0031 1 None None None 146306765 Common rumA 23S rRNA 5-methyluridine methyltransferase Pmen_1734 198 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 146306075 Common - hypothetical protein Pmen_1040 3 None None None 146306497 Common - hypothetical protein Pmen_1465 1 None None None 146305913 Common - Mammalian cell entry related domain protein Pmen_0878 99 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 146305368 Common - 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase Pmen_0327 130 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 146306236 Common - deoxyribodipyrimidine photolyase-related protein Pmen_1204 59 COG3046 COG3046, Uncharacterized protein related to deoxyribodipyrimidine photolyase General function prediction only 146307511 Common - hypothetical protein Pmen_2488 29 COG5343 COG5343, Uncharacterized protein conserved in bacteria Function unknown 146308681 Common - protein of unknown function UPF0016 Pmen_3666 62 COG2119 COG2119, Predicted membrane protein Function unknown 146306922 Common - short chain dehydrogenase Pmen_1892 225 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 146309166 Common - protein of unknown function YGGT Pmen_4152 117 COG0762 COG0762, Predicted integral membrane protein Function unknown 146305700 Common - Urease accessory protein UreF Pmen_0665 77 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 146309433 Common - two component, sigma54 specific, transcriptional regulator, Fis family Pmen_4419 173 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 146308519 Common - Nucleoside-diphosphate kinase Pmen_3504 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 146307784 Common - uracil-xanthine permease Pmen_2762 127 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 146306620 Common - ErfK/YbiS/YcfS/YnhG family protein Pmen_1589 28 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 146307394 Common - hypothetical protein Pmen_2369 19 None None None 146306118 Common - alkylhydroperoxidase like protein, AhpD family Pmen_1084 81 COG2128 COG2128, Uncharacterized conserved protein Function unknown 146305583 Common - type IV pilus secretin PilQ Pmen_0546 143 COG4796 HofQ, Type II secretory pathway, component HofQ Intracellular trafficking and secretion 146308691 Common - hypothetical protein Pmen_3676 1 None None None 146308947 Common argC N-acetyl-gamma-glutamyl-phosphate reductase Pmen_3933 213 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 146309165 Common - pyrroline-5-carboxylate reductase Pmen_4151 213 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 146305803 Common - hypothetical protein Pmen_0768 1 None None None 146309276 Common - hypothetical protein Pmen_4262 103 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 146309397 Common pyrE orotate phosphoribosyltransferase Pmen_4383 106 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 146305235 Pathogen - hypothetical protein Pmen_0194 1 None None None 146305965 Common - peptidase M23B Pmen_0930 189 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 146307818 Common - putative CheW protein Pmen_2796 141 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 146307169 Common - Flavin-containing monooxygenase Pmen_2142 93 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 146309352 Common - Methyltransferase type 11 Pmen_4338 72 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 146309451 Common - hypothetical protein Pmen_4437 3 None None None 146307936 Common - polar amino acid ABC transporter, inner membrane subunit Pmen_2914 172 COG4160 ArtM, ABC-type arginine/histidine transport system, permease component Amino acid transport and metabolism 146308389 Common lysS lysyl-tRNA synthetase Pmen_3370 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 146306156 Common - protein of unknown function DUF479 Pmen_1122 33 COG3124 COG3124, Uncharacterized protein conserved in bacteria Function unknown 146306827 Common - nucleoside recognition domain protein Pmen_1796 20 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 146306080 Common - PilT protein domain protein Pmen_1045 71 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 146306245 Common - Uncharacterized protein UPF0065 Pmen_1213 73 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 146306111 Common hemH ferrochelatase Pmen_1077 157 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 146307149 Pathogen - hypothetical protein Pmen_2122 1 None None None 146309378 Common - transcriptional regulator, LysR family Pmen_4364 181 COG0583 LysR, Transcriptional regulator Transcription 146309150 Common - Oxidoreductase FAD-binding domain protein Pmen_4136 170 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 146309587 Common - precorrin-2 C(20)-methyltransferase Pmen_4573 106 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 146308126 Common - hypothetical protein Pmen_3105 7 None None None 146307280 Common - hypothetical protein Pmen_2254 9 None None None 146308252 Common - protein of unknown function DUF6, transmembrane Pmen_3232 95 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 146305884 Common - Auxin Efflux Carrier Pmen_0849 75 COG0679 COG0679, Predicted permeases General function prediction only 146308052 Common ispD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Pmen_3031 190 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 146305466 Common - Transposase and inactivated derivatives-like protein Pmen_0426 42 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 146309028 Common apaG ApaG Pmen_4014 89 COG2967 ApaG, Uncharacterized protein affecting Mg2+/Co2+ transport Inorganic ion transport and metabolism 146305953 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase Pmen_0918 206 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 146307342 Common - hypothetical protein Pmen_2317 150 COG3455 COG3455, Uncharacterized protein conserved in bacteria Function unknown 146305452 Common - protein of unknown function DUF558 Pmen_0412 202 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 146307052 Common - Patatin Pmen_2024 4 None None None 146307453 Common - acriflavin resistance protein Pmen_2430 183 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 146307857 Common - flagellin domain protein Pmen_2835 119 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 146305633 Common - acyl-CoA dehydrogenase domain protein Pmen_0598 143 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 146305668 Common mutL DNA mismatch repair protein Pmen_0633 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 146308675 Common - protein of unknown function DUF1302 Pmen_3660 18 None None None 146305575 Common - nuclease (SNase domain protein) Pmen_0538 51 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 146309370 Common - outer membrane porin Pmen_4356 7 None None None 146305767 Common - penicillin-binding protein 1C Pmen_0732 200 COG4953 PbpC, Membrane carboxypeptidase/penicillin-binding protein PbpC Cell envelope biogenesis, outer membrane 146305606 Common - protein of unknown function DUF519 Pmen_0569 85 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 146307179 Common - helix-turn-helix- domain containing protein, AraC type Pmen_2152 36 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 146309087 Common - imidazolonepropionase Pmen_4073 107 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 146307352 Common - virulence protein, SciE type Pmen_2327 23 COG4455 ImpE, Protein of avirulence locus involved in temperature-dependent protein secretion General function prediction only 146305609 Common - peptide methionine sulfoxide reductase Pmen_0572 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 146305193 Common - homoserine kinase Pmen_0152 63 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 146306162 Common - beta-lactamase domain protein Pmen_1128 37 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 146305275 Common - transcriptional regulator, TetR family Pmen_0234 70 COG1309 AcrR, Transcriptional regulator Transcription 146306373 Common - putative transcriptional regulator, MerR family Pmen_1341 69 COG0789 SoxR, Predicted transcriptional regulators Transcription 146308437 Common - multicopper oxidase, type 3 Pmen_3418 129 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 146307336 Common - protein of unknown function DUF214 Pmen_2311 8 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 146308077 Common - hypothetical protein Pmen_3056 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 146308842 Common - GCN5-related N-acetyltransferase Pmen_3827 29 COG0456 RimI, Acetyltransferases General function prediction only 146305568 Common - protein of unknown function DUF971 Pmen_0531 50 COG3536 COG3536, Uncharacterized protein conserved in bacteria Function unknown 146308400 Common - Mn2+ and Fe2+ transporter of the NRAMP family-like protein Pmen_3381 23 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 146308313 Common - protein of unknown function DUF1089 Pmen_3293 14 COG3554 COG3554, Uncharacterized protein conserved in bacteria Function unknown 146306369 Common - Sel1 domain protein repeat-containing protein Pmen_1337 66 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 146307542 Common - ATP-NAD/AcoX kinase Pmen_2519 26 COG3199 COG3199, Uncharacterized conserved protein Function unknown 146309567 Common cls cardiolipin synthetase Pmen_4553 152 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 146308025 Common - diguanylate phosphodiesterase Pmen_3003 157 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 146305942 Common - ClpXP protease specificity-enhancing factor Pmen_0907 64 COG2969 SspB, Stringent starvation protein B General function prediction only 146306744 Common - MiaB-like tRNA modifying enzyme YliG Pmen_1713 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 146306844 Common - diguanylate cyclase Pmen_1813 177 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 146305999 Common - glycine oxidase ThiO Pmen_0964 149 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 146307900 Common phnP carbon-phosphorus lyase complex accessory protein Pmen_2878 78 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 146307704 Common - Ethanolamine ammonia lyase large subunit Pmen_2682 55 COG4303 EutB, Ethanolamine ammonia-lyase, large subunit Amino acid transport and metabolism 146309593 Common - transcriptional regulator, LysR family Pmen_4579 154 COG0583 LysR, Transcriptional regulator Transcription 146306511 Common - transcriptional regulator, LysR family Pmen_1479 188 COG0583 LysR, Transcriptional regulator Transcription 146308884 Common - MotA/TolQ/ExbB proton channel Pmen_3870 16 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 146307140 Common - Zonular occludens toxin Pmen_2112 8 COG4128 Zot, Zonula occludens toxin General function prediction only 146307549 Common - Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B Pmen_2526 86 COG3384 COG3384, Uncharacterized conserved protein Function unknown 146308895 Common - catalase/peroxidase HPI Pmen_3881 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 146308659 Common - acetate kinase Pmen_3644 161 COG0282 ackA, Acetate kinase Energy production and conversion 146305626 Common - glycosyl transferase, group 1 Pmen_0589 71 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 146307180 Common - FAD dependent oxidoreductase Pmen_2153 107 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 146306545 Common - putative transcriptional regulator, GntR family Pmen_1514 203 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 146308818 Pathogen - alpha/beta hydrolase fold Pmen_3803 3 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 146305263 Common - transcriptional regulator, LysR family Pmen_0222 190 COG0583 LysR, Transcriptional regulator Transcription 146305355 Common - flagellar basal body-associated protein FliL-like protein Pmen_0314 22 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 146309254 Common - peptidase S45, penicillin amidase Pmen_4240 78 COG2366 COG2366, Protein related to penicillin acylase General function prediction only 146306051 Common - SMC domain protein Pmen_1016 39 COG4637 COG4637, Predicted ATPase General function prediction only 146306802 Common - glutamate dehydrogenase Pmen_1771 173 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 146305391 Common - protein of unknown function DUF47 Pmen_0351 40 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 146306522 Common - Fusaric acid resistance protein conserved region Pmen_1490 45 COG1289 COG1289, Predicted membrane protein Function unknown 146306023 Common - Saccharopine dehydrogenase Pmen_0988 54 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 146306602 Common - methyl-accepting chemotaxis sensory transducer Pmen_1571 145 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146308686 Common - hypothetical protein Pmen_3671 5 None None None 146305447 Common - Protein-glutamate O-methyltransferase Pmen_0407 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 146307160 Common - transcriptional regulator, LysR family Pmen_2133 183 COG0583 LysR, Transcriptional regulator Transcription 146305478 Common - aldehyde dehydrogenase Pmen_0440 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 146306625 Common - glyceraldehyde-3-phosphate dehydrogenase Pmen_1594 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 146307073 Common - binding-protein-dependent transport systems inner membrane component Pmen_2045 155 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 146308592 Common - SAM-dependent methyltransferase-like protein Pmen_3577 138 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 146308537 Common - ABC-type amino acid transport/signal transduction systems periplasmic component/domain-like protein Pmen_3522 7 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146308769 Common - hypothetical protein Pmen_3754 29 None None None 146305532 Common - NADH:flavin oxidoreductase/NADH oxidase Pmen_0495 180 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 146307535 Common - Exonuclease, RNase T and DNA polymerase III Pmen_2512 13 COG5018 KapD, Inhibitor of the KinA pathway to sporulation, predicted exonuclease General function prediction only 146308650 Common lldD L-lactate dehydrogenase Pmen_3635 123 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 146305597 Common - potassium/proton antiporter Pmen_0560 135 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 146305540 Common - gamma-butyrobetaine hydroxylase Pmen_0503 8 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 146308168 Common - 4'-phosphopantetheinyl transferase Pmen_3148 37 COG2977 EntD, Phosphopantetheinyl transferase component of siderophore synthetase Secondary metabolites biosynthesis, transport, and catabolism 146306849 Common - protein of unknown function DUF6, transmembrane Pmen_1818 59 COG2962 RarD, Predicted permeases General function prediction only 146308785 Common - hypothetical protein Pmen_3770 6 None None None 146309218 Common - hypothetical protein Pmen_4204 5 COG4188 COG4188, Predicted dienelactone hydrolase General function prediction only 146307328 Common - methyltransferase small Pmen_2303 142 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 146305431 Common - formate dehydrogenase family accessory protein FdhD Pmen_0391 132 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 146306566 Common - monooxygenase, FAD-binding Pmen_1535 85 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 146309019 Common - multi-sensor signal transduction histidine kinase Pmen_4005 163 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 146309305 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Pmen_4291 166 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 146306207 Common - outer membrane efflux protein Pmen_1175 124 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 146305545 Common - fructose-1,6-bisphosphatase Pmen_0508 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 146308498 Common - hypothetical protein Pmen_3483 9 None None None 146307573 Common - hypothetical protein Pmen_2550 3 None None None 146307368 Common - ABC transporter related Pmen_2343 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 146309265 Common - ABC-type amino acid transport/signal transduction systems periplasmic component/domain-like protein Pmen_4251 19 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146306680 Pathogen - hypothetical protein Pmen_1649 1 None None None 146307484 Common - Lysine exporter protein (LYSE/YGGA) Pmen_2461 47 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 146309314 Common - hypothetical protein Pmen_4300 1 None None None 146308421 Common - signal recognition particle protein Pmen_3402 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 146306572 Common - nicotinamide mononucleotide transporter PnuC Pmen_1541 57 COG3201 PnuC, Nicotinamide mononucleotide transporter Coenzyme metabolism 146308064 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase Pmen_3043 153 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 146307739 Common truA tRNA pseudouridine synthase A Pmen_2717 236 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 146307819 Common - putative CheW protein Pmen_2797 14 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 146305065 Common - type III secretion outer membrane pore, YscC/HrcC family Pmen_0023 108 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 146306335 Common - bifunctional deaminase-reductase domain protein Pmen_1303 74 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 146306646 Common - protein of unknown function DUF343 Pmen_1615 104 COG2835 COG2835, Uncharacterized conserved protein Function unknown 146306314 Common - quinolinate synthetase Pmen_1282 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 146305904 Common - sigma 54 modulation protein/ribosomal protein S30EA Pmen_0869 140 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 146307897 Common - Glu/Leu/Phe/Val dehydrogenase, dimerisation region Pmen_2875 142 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 146308174 Common - hypothetical protein Pmen_3154 13 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 162286125 Common - lipid A biosynthesis lauroyl acyltransferase Pmen_0016 116 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 146308933 Common rplA 50S ribosomal protein L1 Pmen_3919 244 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 146305939 Common - Cytochrome b/b6, N-terminal domain Pmen_0904 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 146306226 Pathogen - hypothetical protein Pmen_1194 2 None None None 146307654 Common - hypothetical protein Pmen_2631 1 None None None 146308638 Common - chaperone protein DnaJ Pmen_3623 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 146305422 Common - thioesterase superfamily protein Pmen_0382 56 COG0824 FcbC, Predicted thioesterase General function prediction only 146309122 Common - N-acetylglucosamine-binding protein A Pmen_4108 32 COG3397 COG3397, Uncharacterized protein conserved in bacteria Function unknown 146308955 Common - Ubiquinone biosynthesis protein COQ7-like protein Pmen_3941 50 COG2941 CAT5, Ubiquinone biosynthesis protein COQ7 Coenzyme metabolism 146308998 Pathogen - hypothetical protein Pmen_3984 1 None None None 146308411 Pathogen - hypothetical protein Pmen_3392 1 None None None 146308977 Pathogen - hypothetical protein Pmen_3963 1 None None None 146307806 Common - cytochrome C biogenesis protein Pmen_2784 92 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 146309525 Common - hypothetical protein Pmen_4511 3 None None None 146306659 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase Pmen_1628 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 146308355 Common - hypothetical protein Pmen_3336 20 None None None 146307686 Common - Amidohydrolase 3 Pmen_2664 101 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 146309466 Common - luciferase family protein Pmen_4452 112 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 146309359 Common - sulfate ABC transporter, periplasmic sulfate-binding protein Pmen_4345 90 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 146305107 Common pbpG D-alanyl-D-alanine endopeptidase Pmen_0066 143 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 146306871 Common - protein of unknown function DUF1289 Pmen_1840 3 COG3313 COG3313, Predicted Fe-S protein General function prediction only 146305817 Common - methyl-accepting chemotaxis sensory transducer Pmen_0782 147 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146308986 Common - phage portal protein, HK97 family Pmen_3972 67 COG4695 COG4695, Phage-related protein Function unknown 146308297 Common - short-chain dehydrogenase/reductase SDR Pmen_3277 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 146307211 Common - Alcohol dehydrogenase, zinc-binding domain protein Pmen_2184 171 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 146309414 Common - hypothetical protein Pmen_4400 7 None None None 146307022 Common - Propeptide, PepSY amd peptidase M4 Pmen_1994 19 COG3212 COG3212, Predicted membrane protein Function unknown 146308929 Common - DNA-directed RNA polymerase subunit beta' Pmen_3915 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 146309344 Common - binding-protein-dependent transport systems inner membrane component Pmen_4330 201 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 146306689 Common - peptidase M48, Ste24p Pmen_1658 126 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 146305492 Common - Methyltransferase type 11 Pmen_0455 132 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 146308512 Common - Pyrrolo-quinoline quinone Pmen_3497 119 COG1520 COG1520, FOG: WD40-like repeat Function unknown 146309423 Common ubiA 4-hydroxybenzoate octaprenyltransferase Pmen_4409 191 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 146307948 Common - hypothetical protein Pmen_2926 7 None None None 146308365 Common - ybaK/ebsC protein Pmen_3346 102 COG2606 EbsC, Uncharacterized conserved protein Function unknown 146307189 Common - HPP family protein+B94 Pmen_2162 64 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 146305303 Common - hypothetical protein Pmen_0262 3 None None None 146308797 Common - CBS domain containing protein Pmen_3782 217 COG4535 CorC, Putative Mg2+ and Co2+ transporter CorC Inorganic ion transport and metabolism 146307264 Common - hypothetical protein Pmen_2238 5 COG5642 COG5642, Uncharacterized conserved protein Function unknown 146306669 Common - transcriptional regulator, TetR family Pmen_1638 98 COG1309 AcrR, Transcriptional regulator Transcription 146305869 Common - methylated-DNA--protein-cysteine methyltransferase Pmen_0834 212 COG2169 Ada, Adenosine deaminase Nucleotide transport and metabolism 146306107 Common - Protein of unknown function DUF1722 Pmen_1073 73 COG3272 COG3272, Uncharacterized conserved protein Function unknown 146309174 Common - general secretion pathway protein D Pmen_4160 141 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 146309606 Common - methionine aminopeptidase, type I Pmen_4592 248 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 146307204 Common - protein of unknown function DUF419 Pmen_2177 16 COG2315 MmcQ, Uncharacterized protein conserved in bacteria Function unknown 146308664 Common - OmpA/MotB domain protein Pmen_3649 167 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 146309036 Common - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase Pmen_4022 109 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 146306000 Common - two component, sigma54 specific, transcriptional regulator, Fis family Pmen_0965 222 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 146305570 Common - ATP-dependent protease peptidase subunit Pmen_0533 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 146306145 Pathogen - hypothetical protein Pmen_1111 1 None None None 146305947 Common - Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase Pmen_0912 207 COG0313 COG0313, Predicted methyltransferases General function prediction only 146307006 Common rpmI 50S ribosomal protein L35 Pmen_1978 141 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 146306334 Common - RarD protein, DMT superfamily transporter Pmen_1302 96 COG2962 RarD, Predicted permeases General function prediction only 146307830 Common flhA flagellar biosynthesis protein A Pmen_2808 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 146309077 Common - 3-phytase Pmen_4063 19 COG4247 Phy, 3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase) Lipid metabolism 146307428 Common - hypothetical protein Pmen_2405 6 None None None 146307664 Common - Rhodanese domain protein Pmen_2642 52 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 146305543 Common - hypothetical protein Pmen_0506 10 None None None 146306006 Common - transcriptional regulator, TetR family Pmen_0971 105 COG1309 AcrR, Transcriptional regulator Transcription 146309399 Common - hypothetical protein Pmen_4385 25 COG3296 COG3296, Uncharacterized protein conserved in bacteria Function unknown 146309426 Pathogen - Anti-sigma-28 factor, FlgM family protein Pmen_4412 2 None None None 146306829 Common - diguanylate phosphodiesterase Pmen_1798 161 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 146307409 Common - recombination factor protein RarA Pmen_2386 222 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 146309057 Common - diguanylate cyclase Pmen_4043 168 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 146305972 Common - 2-dehydropantoate 2-reductase Pmen_0937 112 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 146305711 Common - glutamine synthetase, catalytic region Pmen_0676 221 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 146306129 Common - Cyanophycinase and related exopeptidase-like protein Pmen_1095 15 COG4242 CphB, Cyanophycinase and related exopeptidases Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism 146306661 Common - 3-oxoacyl-(acyl carrier protein) synthase II Pmen_1630 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 146309168 Common - GTPase (dynamin-related)-like protein Pmen_4154 27 COG0699 COG0699, Predicted GTPases (dynamin-related) General function prediction only 146307801 Pathogen - hypothetical protein Pmen_2779 1 None None None 146305958 Common murC UDP-N-acetylmuramate--L-alanine ligase Pmen_0923 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 146305411 Common - Mammalian cell entry related domain protein Pmen_0371 91 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 146306799 Common - hypothetical protein Pmen_1768 1 None None None 146307529 Common - Succinate dehydrogenase hydrophobic anchor subunit-like protein Pmen_2506 52 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 146306873 Common - diguanylate cyclase Pmen_1842 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 146305418 Common - transcriptional regulator, LysR family Pmen_0378 138 COG0583 LysR, Transcriptional regulator Transcription 146305048 Common - phospholipid/glycerol acyltransferase Pmen_0006 62 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 146306426 Common - argininosuccinate synthase Pmen_1394 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 146305372 Common - glycine cleavage system protein H Pmen_0332 185 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 146305536 Common - Substrate-binding region of ABC-type glycine betaine transport system Pmen_0499 60 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 146307402 Common - DsrH family protein Pmen_2379 3 COG2168 DsrH, Uncharacterized conserved protein involved in oxidation of intracellular sulfur Inorganic ion transport and metabolism 146307212 Common - putative CheW protein Pmen_2185 128 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 146308784 Common - ABC transporter related Pmen_3769 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 146307949 Common - general secretion pathway protein D Pmen_2927 113 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 146308994 Common - transcriptional regulator, TraR/DksA family Pmen_3980 1 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 146309603 Common - precorrin-4 C11-methyltransferase Pmen_4589 201 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 146305933 Common - acyl-CoA dehydrogenase domain protein Pmen_0898 165 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 146306330 Common - NAD(P)H dehydrogenase (quinone) Pmen_1298 97 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 146306366 Common - DGPFAETKE family protein Pmen_1334 44 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 146308596 Common - hypothetical protein Pmen_3581 1 None None None 146306619 Common - transcriptional regulator, TetR family Pmen_1588 79 COG1309 AcrR, Transcriptional regulator Transcription 146307271 Common - TraX family protein Pmen_2245 12 None None None 146308633 Common - hypothetical protein Pmen_3618 1 None None None 146308027 Common - hypothetical protein Pmen_3005 1 COG1289 COG1289, Predicted membrane protein Function unknown 146307040 Common - Homoserine dehydrogenase Pmen_2012 204 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 146305272 Common gabD succinate-semialdehyde dehydrogenase I Pmen_0231 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 146306971 Common - two component transcriptional regulator, LuxR family Pmen_1943 177 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 146305279 Common - major facilitator superfamily MFS_1 Pmen_0238 58 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 146305321 Common hemC porphobilinogen deaminase Pmen_0280 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 146305366 Common - peptidase M24 Pmen_0325 238 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 146305879 Common - extracellular solute-binding protein, family 5 Pmen_0844 207 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 146305632 Common - bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase Pmen_0597 139 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 146308914 Common rpsQ 30S ribosomal protein S17 Pmen_3900 234 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 146306337 Common - MscS Mechanosensitive ion channel Pmen_1305 59 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 146308531 Common - hypothetical protein Pmen_3516 18 COG3134 COG3134, Predicted outer membrane lipoprotein Function unknown 146308960 Common - anthranilate synthase component II Pmen_3946 236 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 146306764 Common cysM cysteine synthase B Pmen_1733 227 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 146307669 Common - DNA polymerase III subunits gamma and tau Pmen_2647 248 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 146306788 Common cobT nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Pmen_1757 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 146306886 Common ihfB integration host factor subunit beta Pmen_1855 203 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 146306345 Common rdgC recombination associated protein Pmen_1313 53 COG2974 RdgC, DNA recombination-dependent growth factor C DNA replication, recombination, and repair 146305533 Common - hypothetical protein Pmen_0496 10 None None None 146308792 Common - hypothetical protein Pmen_3777 15 COG4517 COG4517, Uncharacterized protein conserved in bacteria Function unknown 146305510 Common - alanine dehydrogenase Pmen_0473 166 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 146308359 Common - molydopterin dinucleotide-binding region Pmen_3340 182 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 146306520 Common - hypothetical protein Pmen_1488 1 None None None 146306818 Common - hypothetical protein Pmen_1787 59 COG3825 COG3825, Uncharacterized protein conserved in bacteria Function unknown 146308453 Common - choline/carnitine/betaine transporter Pmen_3436 95 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 146308833 Common - hypothetical protein Pmen_3818 10 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 146307842 Common - anti-sigma-factor antagonist Pmen_2820 13 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 146305152 Pathogen - hypothetical protein Pmen_0111 1 None None None 146307507 Common - OsmC family protein Pmen_2484 57 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 146308092 Common - ABC-type uncharacterized transport system involved in gliding motility auxiliary component-like protein Pmen_3071 19 COG3225 GldG, ABC-type uncharacterized transport system involved in gliding motility, auxiliary component Cell motility and secretion 146306626 Common - Na(+)-translocating NADH-quinone reductase subunit A Pmen_1595 39 COG1726 NqrA, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA Energy production and conversion 146306552 Common - dual specificity protein phosphatase Pmen_1521 28 COG2453 CDC14, Predicted protein-tyrosine phosphatase Signal transduction mechanisms 146308161 Common - keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase Pmen_3141 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 146306231 Common - sodium/hydrogen exchanger Pmen_1199 187 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 146306143 Common - arginine/ornithine antiporter Pmen_1109 78 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 146306822 Common - protein of unknown function DUF6, transmembrane Pmen_1791 89 COG2962 RarD, Predicted permeases General function prediction only 146307019 Common - hypothetical protein Pmen_1991 3 None None None 146308037 Common recA recombinase A Pmen_3015 220 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 146308120 Common - transcriptional regulator, LysR family Pmen_3099 178 COG0583 LysR, Transcriptional regulator Transcription 146306122 Common - Phytanoyl-CoA dioxygenase Pmen_1088 6 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 146305441 Common - TonB family protein Pmen_0401 34 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 146305242 Common glcF glycolate oxidase iron-sulfur subunit Pmen_0201 165 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 146306615 Common - hypothetical protein Pmen_1584 3 None None None 146308892 Common uvrA excinuclease ABC subunit A Pmen_3878 245 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 146307163 Common - hypothetical protein Pmen_2136 16 None None None 146305307 Common dapF diaminopimelate epimerase Pmen_0266 203 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 146307577 Common - Citrate transporter Pmen_2554 34 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 146305083 Pathogen - hypothetical protein Pmen_0042 1 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 146307775 Common - protein of unknown function DUF182 Pmen_2753 103 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 146306811 Common - cyclic nucleotide-binding protein Pmen_1780 100 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 146306092 Common - Tetratricopeptide TPR_2 repeat protein Pmen_1058 103 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 146305885 Common - Carboxymuconolactone decarboxylase Pmen_0850 87 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 146308897 Common rplQ 50S ribosomal protein L17 Pmen_3883 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 146308938 Common - Sporulation domain protein Pmen_3924 9 None None None 146306696 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase Pmen_1665 184 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 146305940 Common - Cytochrome c1-like protein Pmen_0905 43 COG2857 CYT1, Cytochrome c1 Energy production and conversion 146305515 Common - response regulator receiver modulated diguanylate cyclase Pmen_0478 219 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 146306516 Common - putative RNA polymerase, sigma-24 subunit, ECF subfamily Pmen_1484 49 COG4941 COG4941, Predicted RNA polymerase sigma factor containing a TPR repeat domain Transcription 146308276 Common - type IV pilus assembly PilZ Pmen_3256 1 None None None 146306155 Common - regulatory protein, ArsR Pmen_1121 47 COG0640 ArsR, Predicted transcriptional regulators Transcription 146308075 Common - methionine aminopeptidase Pmen_3054 249 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 146306854 Common - putative adenylate/guanylate cyclase Pmen_1823 85 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 146307278 Common - hypothetical protein Pmen_2252 9 None None None 146308982 Pathogen - hypothetical protein Pmen_3968 1 None None None 146308431 Common - hypothetical protein Pmen_3412 53 COG3323 COG3323, Uncharacterized protein conserved in bacteria Function unknown 146309520 Common - protein of unknown function DUF454 Pmen_4506 74 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 146308950 Common - alanine racemase domain protein Pmen_3936 10 COG3616 COG3616, Predicted amino acid aldolase or racemase Amino acid transport and metabolism 146305569 Common hslU ATP-dependent protease ATP-binding subunit Pmen_0532 211 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 146305567 Common - poly(R)-hydroxyalkanoic acid synthase, class II Pmen_0530 73 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 146308328 Common - protein of unknown function DUF853, NPT hydrolase putative Pmen_3308 76 COG0433 COG0433, Predicted ATPase General function prediction only 146305205 Common - multiple antibiotic resistance (MarC)-related protein Pmen_0164 141 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 146309012 Common - phosphoglycolate phosphatase Pmen_3998 209 COG0546 Gph, Predicted phosphatases General function prediction only 146306575 Common - Glutamate synthase (NADPH) Pmen_1544 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 146307459 Common - exonuclease III Pmen_2436 196 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 146307906 Common - phosphonate metabolism Pmen_2884 45 COG3626 PhnI, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 146308070 Common - undecaprenyl diphosphate synthase Pmen_3049 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 146308409 Common - hypothetical protein Pmen_3390 14 COG3789 COG3789, Uncharacterized protein conserved in bacteria Function unknown 146306588 Common - helix-turn-helix- domain containing protein, AraC type Pmen_1557 74 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 146308663 Common - multi-sensor hybrid histidine kinase Pmen_3648 226 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146308414 Common - Protein-disulfide isomerase-like protein Pmen_3395 68 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 146307026 Common - methyl-accepting chemotaxis sensory transducer Pmen_1998 144 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146307146 Pathogen - hypothetical protein Pmen_2119 1 None None None 146307260 Common - two component heavy metal response transcriptional regulator, winged helix family Pmen_2234 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 146308521 Common - ferredoxin, 2Fe-2S type, ISC system Pmen_3506 104 COG0633 Fdx, Ferredoxin Energy production and conversion 146307717 Common - short chain dehydrogenase Pmen_2695 209 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 146309209 Common - hypothetical protein Pmen_4195 8 None None None 146309403 Common rpoZ DNA-directed RNA polymerase subunit omega Pmen_4389 115 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 146305641 Common - Calcineurin phosphoesterase C-terminal domain protein Pmen_0606 81 COG1409 Icc, Predicted phosphohydrolases General function prediction only 146307658 Common - transcriptional regulator, XRE family Pmen_2635 66 COG1396 HipB, Predicted transcriptional regulators Transcription 146308812 Common - rod shape-determining protein RodA Pmen_3797 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 146307185 Common - DNA-binding transcriptional activator Pmen_2158 11 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 146307255 Common - copper-translocating P-type ATPase Pmen_2229 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 146309307 Common - integral membrane sensor signal transduction histidine kinase Pmen_4293 186 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 146309312 Common - protein of unknown function DUF502 Pmen_4298 2 COG2928 COG2928, Uncharacterized conserved protein Function unknown 146306808 Common - hypothetical protein Pmen_1777 2 None None None 146307281 Common - hypothetical protein Pmen_2255 7 None None None 146305707 Common - alpha/beta hydrolase fold Pmen_0672 189 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 146306608 Common - hypothetical protein Pmen_1577 6 None None None 146307349 Common - protein of unknown function DUF796 Pmen_2324 23 COG3157 Hcp, Hemolysin-coregulated protein (uncharacterized) Function unknown 146309527 Common uvrD DNA-dependent helicase II Pmen_4513 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 146309300 Common - glycosyl transferase, family 2 Pmen_4286 22 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 146305343 Common - Ureidoglycolate hydrolase Pmen_0302 35 COG3194 DAL3, Ureidoglycolate hydrolase Nucleotide transport and metabolism 146308615 Common - hypothetical protein Pmen_3600 3 None None None 146306757 Common - DNA polymerase IV Pmen_1726 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 146306451 Common - hypothetical protein Pmen_1419 2 None None None 146305773 Common - hypothetical protein Pmen_0738 15 None None None 146305739 Common - amidase Pmen_0704 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 146306174 Common - 3-oxoacid CoA-transferase, A subunit Pmen_1140 102 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 146308515 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase Pmen_3500 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 146308647 Common smpB SsrA-binding protein Pmen_3632 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 146305573 Common - primosome assembly protein PriA Pmen_0536 213 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 146305605 Common - protein of unknown function DUF45 Pmen_0568 138 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 146307612 Common - hypothetical protein Pmen_2589 4 COG3212 COG3212, Predicted membrane protein Function unknown 146307929 Common - succinylarginine dihydrolase Pmen_2907 34 COG3724 AstB, Succinylarginine dihydrolase Amino acid transport and metabolism 146306077 Pathogen - hypothetical protein Pmen_1042 1 None None None 146307316 Common - Dipeptidyl aminopeptidase/acylaminoacyl-peptidase-like protein Pmen_2291 25 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 146308384 Common - Hydrolase of the alpha/beta superfamily-like protein Pmen_3365 87 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 146308743 Common - DEAD/DEAH box helicase domain protein Pmen_3728 229 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 146308474 Common - formyltetrahydrofolate deformylase Pmen_3457 217 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 146306237 Common - hypothetical protein Pmen_1205 24 COG4338 COG4338, Uncharacterized protein conserved in bacteria Function unknown 146307500 Common - integral membrane sensor signal transduction histidine kinase Pmen_2477 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146309379 Common - FAD dependent oxidoreductase Pmen_4365 103 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 146309371 Common - Tannase and feruloyl esterase Pmen_4357 20 COG1770 PtrB, Protease II Amino acid transport and metabolism 146305979 Common - hypothetical protein Pmen_0944 15 None None None 146306108 Common - hypothetical protein Pmen_1074 11 None None None 146309490 Common - hypothetical protein Pmen_4476 13 None None None 146307134 Common - hypothetical protein Pmen_2106 1 None None None 146308849 Common - ABC transporter related Pmen_3835 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 146308546 Common - Na+/H+ antiporter NhaC Pmen_3531 52 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 146305198 Common - cytochrome c, class I Pmen_0157 62 COG2863 COG2863, Cytochrome c553 Energy production and conversion 146307229 Common - DinB family protein Pmen_2202 32 COG2318 DinB, Uncharacterized protein conserved in bacteria Function unknown 146307321 Common - MgtC/SapB transporter Pmen_2296 120 COG1285 SapB, Uncharacterized membrane protein Function unknown 146308494 Common - luciferase family protein Pmen_3478 112 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 146309391 Common - bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase Pmen_4377 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 146307162 Common - protein of unknown function DUF6, transmembrane Pmen_2135 72 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 146307427 Common - GCN5-related N-acetyltransferase Pmen_2404 105 COG2153 ElaA, Predicted acyltransferase General function prediction only 146309274 Common - hypothetical protein Pmen_4260 72 COG2924 COG2924, Uncharacterized protein conserved in bacteria Function unknown 146308343 Common - diguanylate cyclase/phosphodiesterase Pmen_3323 173 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 146305622 Common - hypothetical protein Pmen_0585 5 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 146306383 Common - protein-disulfide isomerase-like protein Pmen_1351 23 COG3531 COG3531, Predicted protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 146306204 Pathogen - hypothetical protein Pmen_1172 1 None None None 146308065 Common - outer membrane chaperone Skp (OmpH) Pmen_3044 65 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 146306758 Common - protein of unknown function DUF306, Meta and HslJ Pmen_1727 21 COG3187 HslJ, Heat shock protein Posttranslational modification, protein turnover, chaperones 146306241 Common - efflux transporter, RND family, MFP subunit Pmen_1209 170 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 146307003 Common - FAD dependent oxidoreductase Pmen_1975 120 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 146308720 Common - hydroxydechloroatrazine ethylaminohydrolase Pmen_3705 174 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 146305079 Pathogen - type III secretion effector delivery regulator, TyeA family Pmen_0038 2 None None None 146306770 Common - outer membrane porin Pmen_1739 10 None None None 146307520 Common - protein of unknown function DUF599 Pmen_2497 27 COG3821 COG3821, Predicted membrane protein Function unknown 146306495 Common - GcvT-like aminomethyltransferase Pmen_1463 95 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 146308130 Common - CMP/dCMP deaminase, zinc-binding Pmen_3110 62 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 146306060 Common - hypothetical protein Pmen_1025 6 None None None 146308127 Common - hypothetical protein Pmen_3106 25 None None None 146308862 Common ribA GTP cyclohydrolase II Pmen_3848 184 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 146305132 Common - protein of unknown function DUF877 Pmen_0091 50 COG3517 COG3517, Uncharacterized protein conserved in bacteria Function unknown 146309026 Common pdxA 4-hydroxythreonine-4-phosphate dehydrogenase Pmen_4012 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 146307246 Common - copper-resistance protein, CopA family Pmen_2219 123 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 146305911 Common - ABC transporter related Pmen_0876 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 146305945 Common - hypothetical protein Pmen_0910 148 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 146305968 Common - Glutathione S-transferase, N-terminal domain Pmen_0933 76 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 146308808 Common - hypothetical protein Pmen_3793 49 COG2921 COG2921, Uncharacterized conserved protein Function unknown 146306376 Common - serine hydroxymethyltransferase Pmen_1344 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 146305281 Common - putative transcriptional regulator, GntR family Pmen_0240 227 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 146308048 Common - Carboxylesterase Pmen_3027 100 COG0627 COG0627, Predicted esterase General function prediction only 146307397 Common uvrC excinuclease ABC subunit C Pmen_2374 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 146309337 Common - aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein Pmen_4323 119 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 146308932 Common rplJ 50S ribosomal protein L10 Pmen_3918 209 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 146309233 Common - HAD-superfamily subfamily IB hydrolase, TIGR01490 Pmen_4219 88 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 146306621 Common - beta-hexosaminidase Pmen_1590 176 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 146307746 Common - transcriptional regulator, LysR family Pmen_2724 192 COG0583 LysR, Transcriptional regulator Transcription 146305928 Common - hydrolase of the alpha/beta superfamily-like protein Pmen_0893 79 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 146308059 Common dnaE DNA polymerase III subunit alpha Pmen_3038 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 146307222 Common - ATP-dependent DNA ligase Pmen_2195 105 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 146308969 Common - hypothetical protein Pmen_3955 3 None None None 146308315 Common - AzlC family protein Pmen_3295 109 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 146306753 Common - major facilitator superfamily MFS_1 Pmen_1722 170 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 146306319 Common - hypothetical protein Pmen_1287 1 None None None 146306995 Common - pyrroloquinoline quinone biosynthesis protein PqqC Pmen_1967 38 COG5424 COG5424, Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C Coenzyme metabolism 146306647 Common - 3-deoxy-manno-octulosonate cytidylyltransferase Pmen_1616 145 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 146308352 Common - Sel1 domain protein repeat-containing protein Pmen_3333 1 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 146305121 Pathogen - protein of unknown function DUF1328 Pmen_0080 1 COG5487 COG5487, Small integral membrane protein Function unknown 146309584 Common - precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit Pmen_4570 106 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 146306715 Common - alpha/beta hydrolase fold Pmen_1684 98 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 146305732 Common - ABC transporter related Pmen_0697 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 146307512 Common - hypothetical protein Pmen_2489 15 None None None 146305737 Common - transcriptional regulator, GntR family Pmen_0702 130 COG1802 GntR, Transcriptional regulators Transcription 146306978 Common - integral membrane sensor signal transduction histidine kinase Pmen_1950 130 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 146309556 Common - Serralysin Pmen_4542 72 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 146308260 Common - phosphate-starvation-inducible E Pmen_3240 17 COG3223 COG3223, Predicted membrane protein Function unknown 146306050 Common - Mammalian cell entry related domain protein Pmen_1015 56 COG3008 PqiB, Paraquat-inducible protein B General function prediction only 146307789 Common - transcriptional regulator, TetR family Pmen_2767 116 COG1309 AcrR, Transcriptional regulator Transcription 146308152 Common malE maltose ABC transporter periplasmic protein Pmen_3132 88 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 146308041 Common - RNA polymerase sigma factor RpoS Pmen_3020 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 146306635 Common - glycerophosphoryl diester phosphodiesterase Pmen_1604 163 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 146305232 Common - RNA polymerase, sigma 28 subunit, FliA/WhiG Pmen_0191 126 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 146308777 Common - addiction module toxin, RelE/StbE family Pmen_3762 33 COG3668 ParE, Plasmid stabilization system protein General function prediction only 146308844 Common - inorganic pyrophosphatase Pmen_3829 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 146307203 Common - protein of unknown function DUF1294 Pmen_2176 55 COG3326 COG3326, Predicted membrane protein Function unknown 146306526 Common - alpha/beta hydrolase fold Pmen_1494 112 COG2267 PldB, Lysophospholipase Lipid metabolism 146308803 Common holA DNA polymerase III subunit delta Pmen_3788 123 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 146306851 Common - helix-turn-helix- domain containing protein, AraC type Pmen_1820 79 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 146306603 Common - putative CheW protein Pmen_1572 168 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 146309330 Common - sulfate ABC transporter, inner membrane subunit CysW Pmen_4316 212 COG4208 CysW, ABC-type sulfate transport system, permease component Inorganic ion transport and metabolism 146305139 Common - transcriptional regulator, Fis family Pmen_0098 171 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 146306668 Common - aminotransferase, class V Pmen_1637 230 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 146307812 Common - heme exporter protein CcmB Pmen_2790 43 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 146305388 Common - binding-protein-dependent transport systems inner membrane component Pmen_0348 190 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 146307436 Common - NADH dehydrogenase subunit B Pmen_2413 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 146306352 Common - diguanylate cyclase/phosphodiesterase Pmen_1320 168 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 146307196 Common - sigma54 specific transcriptional regulator, Fis family Pmen_2169 161 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 146306032 Common - hypothetical protein Pmen_0997 17 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 146306403 Common - 3-hydroxyisobutyrate dehydrogenase Pmen_1371 164 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 146309196 Common - GAF sensor signal transduction histidine kinase Pmen_4182 149 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 146305309 Common - helix-turn-helix- domain containing protein, AraC type Pmen_0268 79 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 146305461 Common - extracellular solute-binding protein, family 3 Pmen_0421 33 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146308335 Common - protein of unknown function DUF975 Pmen_3315 19 COG5473 COG5473, Predicted integral membrane protein Function unknown 146309037 Common - dihydroneopterin aldolase Pmen_4023 50 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 146305867 Common - Xanthine/uracil/vitamin C permease Pmen_0832 134 COG2252 COG2252, Permeases General function prediction only 146305488 Common - Cytochrome c556-like protein Pmen_0451 18 COG3909 COG3909, Cytochrome c556 Energy production and conversion 146305909 Common - 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family Pmen_0874 103 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 146305829 Common - two component transcriptional regulator, winged helix family Pmen_0794 215 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 146307373 Common - protein of unknown function DUF72 Pmen_2348 106 COG1801 COG1801, Uncharacterized conserved protein Function unknown 146308687 Common - phospholipid/glycerol acyltransferase Pmen_3672 17 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 146305385 Common - extracellular solute-binding protein, family 1 Pmen_0345 131 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 146307000 Common - PAS/PAC sensor hybrid histidine kinase Pmen_1972 215 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146305342 Common - Ppx/GppA phosphatase Pmen_0301 180 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 146307982 Common - 3-methyladenine DNA glycosylase-like protein Pmen_2960 64 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 146305115 Common - hypothetical protein Pmen_0074 2 None None None 146309092 Common - protein of unknown function DUF344 Pmen_4078 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 146307838 Common fliL flagellar basal body-associated protein FliL Pmen_2816 29 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 146307544 Common - methionine sulfoxide reductase B Pmen_2521 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 146307988 Common - hypothetical protein Pmen_2966 26 COG3091 SprT, Uncharacterized protein conserved in bacteria Function unknown 146307084 Common - short-chain dehydrogenase/reductase SDR Pmen_2056 235 COG0623 FabI, Enoyl- acyl-carrier-protein 146306312 Common - Radical SAM domain protein Pmen_1280 171 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 146307154 Common - putative transcriptional regulator, CopG/Arc/MetJ family Pmen_2127 14 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 146309084 Common - urocanate hydratase Pmen_4070 97 COG2987 HutU, Urocanate hydratase Amino acid transport and metabolism 146307171 Common - DEAD/DEAH box helicase domain protein Pmen_2144 233 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 146305659 Common - flagellar motor protein MotA Pmen_0624 104 COG1291 MotA, Flagellar motor component Cell motility and secretion 146307469 Common - Acyl-CoA thioesterase-like protein Pmen_2446 51 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 146307979 Common - peptidase M42 family protein Pmen_2957 77 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 146306115 Common - alkylphosphonate utilization operon protein PhnA Pmen_1081 88 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 146308894 Common - bacterioferritin Pmen_3880 99 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 146307881 Common - sodium:dicarboxylate symporter Pmen_2859 128 COG3633 SstT, Na+/serine symporter Amino acid transport and metabolism 146308767 Common - hypothetical protein Pmen_3752 13 None None None 146307451 Common - RND efflux system, outer membrane lipoprotein, NodT family Pmen_2428 121 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 146308696 Common rpmA 50S ribosomal protein L27 Pmen_3681 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 146309357 Common - protein of unknown function DUF1234 Pmen_4343 51 COG3545 COG3545, Predicted esterase of the alpha/beta hydrolase fold General function prediction only 146307230 Common - ABC transporter related Pmen_2203 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 146308817 Common proA gamma-glutamyl phosphate reductase Pmen_3802 188 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 146305356 Common - ABC-2 type transporter Pmen_0315 107 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 146309066 Common - extracellular solute-binding protein, family 1 Pmen_4052 121 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 146306439 Common - putative cold-shock DNA-binding domain protein Pmen_1407 179 COG1278 CspC, Cold shock proteins Transcription 146307148 Pathogen - hypothetical protein Pmen_2121 1 COG2452 COG2452, Predicted site-specific integrase-resolvase DNA replication, recombination, and repair 146306039 Common - protein of unknown function DUF446 Pmen_1004 33 COG3098 COG3098, Uncharacterized protein conserved in bacteria Function unknown 146308296 Common - enoyl-CoA hydratase Pmen_3276 154 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 146305855 Common - Rhs element Vgr protein Pmen_0820 57 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 146305220 Common - phosphate binding protein Pmen_0179 124 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 146305839 Common - FMN-dependent alpha-hydroxy acid dehydrogenase Pmen_0804 110 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 146306209 Common - heavy metal efflux pump, CzcA family Pmen_1177 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 146308585 Common - isochorismatase hydrolase Pmen_3570 85 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 146309172 Common - putative deoxyribonucleotide triphosphate pyrophosphatase Pmen_4158 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 146306190 Common - transcriptional regulator, LysR family Pmen_1156 166 COG0583 LysR, Transcriptional regulator Transcription 146306950 Common - efflux transporter, RND family, MFP subunit Pmen_1921 175 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 146306084 Common - transposase IS66 Pmen_1050 67 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 146308594 Common - anaerobic nitric oxide reductase transcription regulator Pmen_3579 171 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 146307853 Common fliS flagellar protein FliS Pmen_2831 83 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 146309585 Common - precorrin-3B synthase Pmen_4571 68 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 146308144 Common - alpha/beta hydrolase fold Pmen_3124 29 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 146306901 Common - hypothetical protein Pmen_1871 2 None None None 146308514 Common hisS histidyl-tRNA synthetase Pmen_3499 248 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 146307709 Common - hypothetical protein Pmen_2687 7 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 146308113 Common - hypothetical protein Pmen_3092 5 None None None 146309464 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) Pmen_4450 188 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 146305509 Common - band 7 protein Pmen_0472 200 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 146306919 Common - helix-turn-helix- domain containing protein, AraC type Pmen_1889 49 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 146305616 Common - lipopolysaccharide heptosyltransferase II Pmen_0579 108 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 146305504 Common - hypothetical protein Pmen_0467 23 None None None 146307463 Common - transcriptional regulator, LysR family Pmen_2440 96 COG0583 LysR, Transcriptional regulator Transcription 146308303 Common - flavodoxin Pmen_3283 58 COG0716 FldA, Flavodoxins Energy production and conversion 146308425 Common purT phosphoribosylglycinamide formyltransferase 2 Pmen_3406 206 COG0027 PurT, Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Nucleotide transport and metabolism 146305183 Common - cytochrome c oxidase, subunit II Pmen_0142 151 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 146306936 Common - MATE efflux family protein Pmen_1907 179 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 146306908 Common - polysaccharide biosynthesis protein CapD Pmen_1878 158 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 146306878 Common mtnA methylthioribose-1-phosphate isomerase Pmen_1847 128 COG0182 COG0182, Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 146307497 Common - phosphoesterase, PA-phosphatase related Pmen_2474 28 COG3907 COG3907, PAP2 (acid phosphatase) superfamily protein General function prediction only 146308198 Common - hypothetical protein Pmen_3178 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 146305354 Common - Alcohol dehydrogenase, zinc-binding domain protein Pmen_0313 181 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 146309055 Common - integral membrane sensor hybrid histidine kinase Pmen_4041 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146308578 Common - cyclic nucleotide-binding protein Pmen_3563 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 146306393 Common - ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components-like protein Pmen_1361 71 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 146305195 Common - DNA polymerase I Pmen_0154 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 146306101 Common - protein of unknown function DUF1365 Pmen_1067 61 COG3496 COG3496, Uncharacterized conserved protein Function unknown 146306160 Common - Putative hemolysin-like protein Pmen_1126 61 COG3176 COG3176, Putative hemolysin General function prediction only 146306968 Common - domain of unknown function DUF1745 Pmen_1939 35 COG3287 COG3287, Uncharacterized conserved protein Function unknown 146306478 Common - putative monovalent cation/H+ antiporter subunit G Pmen_1446 97 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 146307605 Common - hypothetical protein Pmen_2582 16 None None None 146306414 Common - hypothetical protein Pmen_1382 13 None None None 146305788 Common - protein of unknown function DUF465 Pmen_0753 25 COG2841 COG2841, Uncharacterized protein conserved in bacteria Function unknown 146308367 Common glpD glycerol-3-phosphate dehydrogenase Pmen_3348 148 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 146307682 Common - arginine/ornithine antiporter Pmen_2660 131 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 146309440 Common - flagellar biosynthesis protein FlhA Pmen_4426 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 146307610 Common - amidotransferase Pmen_2587 147 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 146307641 Common - metal-dependent hydrolase-like protein Pmen_2618 25 COG3687 COG3687, Predicted metal-dependent hydrolase General function prediction only 146308564 Common - nucleoid-associated protein NdpA Pmen_3549 31 COG3081 COG3081, Nucleoid-associated protein General function prediction only 146309103 Common - hypothetical protein Pmen_4089 3 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 146306482 Common - FAD dependent oxidoreductase Pmen_1450 82 COG2509 COG2509, Uncharacterized FAD-dependent dehydrogenases General function prediction only 146306197 Common - IS66 Orf2 family protein Pmen_1164 50 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 146309511 Common - ABC transporter related Pmen_4497 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 146308883 Common - Biopolymer transport protein ExbD/TolR Pmen_3869 126 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 146307013 Common - exodeoxyribonuclease V, gamma subunit Pmen_1985 67 COG1330 RecC, Exonuclease V gamma subunit DNA replication, recombination, and repair 146306272 Common - putative serine protein kinase, PrkA Pmen_1240 7 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 146309476 Common - nucleic-acid-binding protein containing a Zn-ribbon domain-like protein Pmen_4462 19 COG3529 COG3529, Predicted nucleic-acid-binding protein containing a Zn-ribbon domain General function prediction only 146306841 Common - protein of unknown function DUF454 Pmen_1810 57 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 146305730 Common ureA urease subunit gamma Pmen_0695 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 146306443 Common - nicotinate phosphoribosyltransferase Pmen_1411 95 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 146308472 Common - hypothetical protein Pmen_3455 22 None None None 146309448 Common - hypothetical protein Pmen_4434 1 COG5457 COG5457, Uncharacterized conserved small protein Function unknown 146307486 Common - thioesterase superfamily protein Pmen_2463 84 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 146305781 Common - cytochrome bd ubiquinol oxidase, subunit I Pmen_0746 165 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 146308134 Common - aromatic amino acid aminotransferase Pmen_3114 72 COG1448 TyrB, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 146305754 Common - type I secretion membrane fusion protein, HlyD family Pmen_0719 125 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 146305831 Common - TonB-dependent receptor Pmen_0796 76 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 146306202 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Pmen_1169 62 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 146307132 Common - nitrate ABC transporter, inner membrane subunit Pmen_2104 192 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 146309216 Common - binding-protein-dependent transport systems inner membrane component Pmen_4202 152 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 146306274 Common - membrane protein-like protein Pmen_1242 23 COG3205 COG3205, Predicted membrane protein Function unknown 146307908 Common - phosphonate metabolism PhnG Pmen_2886 31 COG3624 PhnG, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 146306466 Common - beta-lactamase Pmen_1434 97 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 146307341 Common - ImcF domain protein Pmen_2316 47 COG3523 IcmF, Uncharacterized protein conserved in bacteria Function unknown 146307902 Common - phosphonate metabolism protein PhnM Pmen_2880 52 COG3454 COG3454, Metal-dependent hydrolase involved in phosphonate metabolism Inorganic ion transport and metabolism 146307734 Common - Colicin V production protein Pmen_2712 87 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 146305203 Common - diguanylate cyclase Pmen_0162 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 146308203 Common - protein phosphatase 2C domain protein Pmen_3183 119 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 146305595 Common - hypothetical protein Pmen_0558 110 COG0397 COG0397, Uncharacterized conserved protein Function unknown 146309124 Common - hypothetical protein Pmen_4110 12 COG4700 COG4700, Uncharacterized protein conserved in bacteria containing a divergent form of TPR repeats Function unknown 146305429 Common - formate dehydrogenase, alpha subunit Pmen_0389 215 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 146307437 Common - bifunctional NADH:ubiquinone oxidoreductase subunit C/D Pmen_2414 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 146308395 Common - single-stranded-DNA-specific exonuclease RecJ Pmen_3376 195 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 146308946 Common - hypothetical protein Pmen_3932 16 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 146309362 Common - sulfate ABC transporter, ATPase subunit Pmen_4348 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 146307236 Common - hypothetical protein Pmen_2209 3 None None None 146307619 Common - protein of unknown function DUF403 Pmen_2596 82 COG2307 COG2307, Uncharacterized protein conserved in bacteria Function unknown 146308012 Common - flavodoxin/nitric oxide synthase Pmen_2990 115 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 146305997 Common - Tfp pilus assembly protein FimT-like protein Pmen_0962 1 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 146309116 Common - membrane protein-like protein Pmen_4102 53 COG4327 COG4327, Predicted membrane protein Function unknown 146307096 Common - Lysine decarboxylase Pmen_2068 87 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 146307594 Common cysS cysteinyl-tRNA synthetase Pmen_2571 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 146308082 Common - Fe-S metabolism associated SufE Pmen_3061 84 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 146305725 Common - hypothetical protein Pmen_0690 24 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 146309018 Common - two component transcriptional regulator, LuxR family Pmen_4004 198 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 146305587 Common gltB glutamate synthase subunit alpha Pmen_0550 204 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 146306540 Common - NADP oxidoreductase, coenzyme F420-dependent Pmen_1508 53 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 146309544 Common - hypothetical protein Pmen_4530 12 None None None 146307694 Common - transcriptional regulator, MarR family Pmen_2672 38 COG1846 MarR, Transcriptional regulators Transcription 146308394 Common - protein of unknown function DUF533 Pmen_3375 28 COG2979 COG2979, Uncharacterized protein conserved in bacteria Function unknown 146306181 Common glk glucokinase Pmen_1147 91 COG0837 Glk, Glucokinase Carbohydrate transport and metabolism 146305093 Common trkA potassium transporter peripheral membrane component Pmen_0052 140 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 146308936 Common secE preprotein translocase subunit SecE Pmen_3922 16 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 146308702 Common groES co-chaperonin GroES Pmen_3687 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 146309615 Common - D-fructose-6-phosphate amidotransferase Pmen_4602 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 146309540 Common - hypothetical protein Pmen_4526 2 None None None 146306172 Common - acetyl-CoA acetyltransferase Pmen_1138 186 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 146307414 Common - arginyl-tRNA-protein transferase Pmen_2391 85 COG2935 COG2935, Putative arginyl-tRNA:protein arginylyltransferase Posttranslational modification, protein turnover, chaperones 146305349 Common - thioredoxin Pmen_0308 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 146309100 Common - Carboxylesterase Pmen_4086 39 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 146305795 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) Pmen_0760 195 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 146307632 Common - hypothetical protein Pmen_2609 22 COG3198 COG3198, Uncharacterized protein conserved in bacteria Function unknown 146306929 Pathogen - hypothetical protein Pmen_1900 1 None None None 146307074 Common - small integral membrane protein-like protein Pmen_2046 26 COG5477 COG5477, Predicted small integral membrane protein Function unknown 146307691 Common - helix-turn-helix- domain containing protein, AraC type Pmen_2669 141 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 146308388 Common - transcriptional regulator, TetR family Pmen_3369 7 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 146309607 Common - methylmalonate-semialdehyde dehydrogenase Pmen_4593 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 146307622 Common - cytochrome c oxidase, cbb3-type, subunit I Pmen_2599 147 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 146305720 Common - hypothetical protein Pmen_0685 12 None None None 146306717 Common - protein of unknown function DUF6, transmembrane Pmen_1686 23 COG2962 RarD, Predicted permeases General function prediction only 146309388 Common rpmB 50S ribosomal protein L28 Pmen_4374 168 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 146306297 Common - Ferritin, Dps family protein Pmen_1265 143 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 146305286 Common - D-amino acid dehydrogenase small subunit Pmen_0245 140 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 146307568 Common - phosphoadenosine phosphosulfate reductase Pmen_2545 115 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 146309369 Common - 3-hydroxybutyrate dehydrogenase Pmen_4355 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 146305128 Common - TRAP dicarboxylate transporter, DctM subunit Pmen_0087 127 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 146305498 Common - hypothetical protein Pmen_0461 1 COG3895 COG3895, Predicted periplasmic protein General function prediction only 146308480 Pathogen - hypothetical protein Pmen_3463 1 None None None 146307620 Common - protein of unknown function DUF404 Pmen_2597 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 146308219 Common - phosphonate ABC transporter, inner membrane subunit Pmen_3199 88 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 146308966 Pathogen - hypothetical protein Pmen_3952 1 None None None 146307720 Pathogen - hypothetical protein Pmen_2698 1 None None None 146306910 Common - hypothetical protein Pmen_1880 3 None None None 146306959 Common - anti-sigma-factor antagonist Pmen_1930 7 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 146307744 Common - 3-isopropylmalate dehydratase, small subunit Pmen_2722 210 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 146308764 Common - hypothetical protein Pmen_3749 212 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 146306727 Common - 4-hydroxyphenylpyruvate dioxygenase Pmen_1696 78 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 146307335 Common - protein of unknown function DUF323 Pmen_2310 27 COG1262 COG1262, Uncharacterized conserved protein Function unknown 146306775 Common - molybdenum cofactor biosynthesis protein B Pmen_1744 188 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 146308746 Common - YbaK/prolyl-tRNA synthetase associated region Pmen_3731 10 COG3760 COG3760, Uncharacterized conserved protein Function unknown 146308847 Common - transcriptional regulator, GntR family Pmen_3833 74 COG1802 GntR, Transcriptional regulators Transcription 146308621 Common - tRNA pseudouridine synthase B Pmen_3606 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 146308600 Common - transcriptional regulator, TraR/DksA family Pmen_3585 149 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 146308771 Common - CRISPR-associated protein, Cse3 family Pmen_3756 32 None None None 146307629 Common - Cbb3-type cytochrome oxidase component Pmen_2606 20 COG4736 CcoQ, Cbb3-type cytochrome oxidase, subunit 3 Posttranslational modification, protein turnover, chaperones 146309631 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA Pmen_4618 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 146306644 Common - Biopolymer transport protein ExbD/TolR Pmen_1613 31 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 146307592 Common - carbohydrate kinase, thermoresistant glucokinase family Pmen_2569 82 COG3265 GntK, Gluconate kinase Carbohydrate transport and metabolism 146305313 Common - lipase, class 3 Pmen_0272 9 COG3675 COG3675, Predicted lipase Lipid metabolism 146308860 Common - periplasmic binding protein Pmen_3846 131 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 146305667 Common - N-acetylmuramoyl-L-alanine amidase Pmen_0632 172 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 146305678 Common - ribonuclease R Pmen_0643 195 COG0557 VacB, Exoribonuclease R Transcription 146305660 Common motB flagellar motor protein MotB Pmen_0625 93 COG1360 MotB, Flagellar motor protein Cell motility and secretion 146308867 Common nusB transcription antitermination protein NusB Pmen_3853 186 COG0781 NusB, Transcription termination factor Transcription 146307361 Common - hypothetical protein Pmen_2336 11 None None None 146308094 Common - ABC transporter related Pmen_3073 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 146306187 Common - ABC transporter related Pmen_1153 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 146306838 Common - hypothetical protein Pmen_1807 2 None None None 146309074 Common - TonB family protein Pmen_4060 11 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 146309435 Common - flagellar motor switch protein FliN Pmen_4421 119 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 146307293 Common - hypothetical protein Pmen_2268 2 None None None 146308271 Common - hypothetical protein Pmen_3251 13 COG3132 COG3132, Uncharacterized protein conserved in bacteria Function unknown 146307300 Common - MscS Mechanosensitive ion channel Pmen_2275 52 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 146309516 Common - Tetratricopeptide TPR_2 repeat protein Pmen_4502 1 None None None 146309221 Common - lactoylglutathione lyase Pmen_4207 122 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 146305264 Common - protein of unknown function DUF1329 Pmen_0223 19 None None None 146306045 Common - CDP-diacylglycerol--serine O-phosphatidyltransferase Pmen_1010 140 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 146307114 Common - hypothetical protein Pmen_2086 14 COG2267 PldB, Lysophospholipase Lipid metabolism 146306066 Common - GDP-mannose 6-dehydrogenase Pmen_1031 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 146309591 Common - flavin reductase domain protein, FMN-binding Pmen_4577 49 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 146307492 Common - 3-hydroxydecanoyl-(acyl carrier protein) dehydratase Pmen_2469 82 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 146306631 Common - Na(+)-translocating NADH-quinone reductase subunit F Pmen_1600 153 COG2871 NqrF, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF Energy production and conversion 146307362 Common - hypothetical protein Pmen_2337 2 None None None 146305983 Common - putative sulfate transporter YchM Pmen_0948 161 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 146306016 Common - hypothetical protein Pmen_0981 5 None None None 146308508 Common - hypothetical protein Pmen_3493 4 None None None 146309329 Common - response regulator receiver modulated diguanylate cyclase Pmen_4315 212 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 146305897 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Pmen_0862 197 COG0388 COG0388, Predicted amidohydrolase General function prediction only 146306256 Common - hypothetical protein Pmen_1224 1 None None None 146307556 Common - hypothetical protein Pmen_2533 4 None None None 146307975 Common - helix-turn-helix- domain containing protein, AraC type Pmen_2953 72 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 146305145 Common - ImcF domain protein Pmen_0104 48 COG3523 IcmF, Uncharacterized protein conserved in bacteria Function unknown 146307968 Common - cyclic nucleotide-binding protein Pmen_2946 48 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 146306117 Common - protein of unknown function DUF6, transmembrane Pmen_1083 52 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 146307808 Common - cytochrome c-type biogenesis protein CcmF Pmen_2786 123 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 146308509 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Pmen_3494 197 COG0388 COG0388, Predicted amidohydrolase General function prediction only 146308568 Common - hypothetical protein Pmen_3553 59 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 146305521 Common - Substrate-binding region of ABC-type glycine betaine transport system Pmen_0484 70 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 146309228 Common - prolipoprotein diacylglyceryl transferase Pmen_4214 207 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 146307656 Common - putative aminotransferase Pmen_2633 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 146309151 Common - Rieske (2Fe-2S) domain protein Pmen_4137 83 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 146307913 Common - Arc domain protein DNA binding domain protein Pmen_2891 6 None None None 146305646 Common - 3-deoxy-D-manno-octulosonic-acid transferase Pmen_0611 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 146307307 Common - glycogen debranching enzyme GlgX Pmen_2282 147 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 146309531 Common - import inner membrane translocase, subunit Tim44 Pmen_4517 29 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 146305252 Common - flagellar basal-body rod protein FlgG Pmen_0211 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 146307054 Common - twitching motility protein Pmen_2026 218 COG5008 PilU, Tfp pilus assembly protein, ATPase PilU Cell motility and secretion / Intracellular trafficking and secretion 146307970 Common - hypothetical protein Pmen_2948 5 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 146307514 Common - heat shock protein 90 Pmen_2491 150 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 146307262 Common - hypothetical protein Pmen_2236 25 None None None 146309014 Common - binding-protein-dependent transport systems inner membrane component Pmen_4000 229 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 146309186 Common - RNA polymerase factor sigma-32 Pmen_4172 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 146305105 Common - sulfatase Pmen_0064 93 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 146306675 Common - protein tyrosine phosphatase-like protein Pmen_1644 20 COG4551 COG4551, Predicted protein tyrosine phosphatase General function prediction only 146309322 Common - fatty acid desaturase Pmen_4308 67 COG1398 OLE1, Fatty-acid desaturase Lipid metabolism 146306594 Common - two component transcriptional regulator, LuxR family Pmen_1563 213 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 146305311 Common - protein of unknown function DUF1289 Pmen_0270 4 COG3313 COG3313, Predicted Fe-S protein General function prediction only 146305558 Common - 2-polyprenylphenol 6-hydroxylase Pmen_0521 183 COG0661 AarF, Predicted unusual protein kinase General function prediction only 146308700 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Pmen_3685 42 COG0748 HugZ, Putative heme iron utilization protein Inorganic ion transport and metabolism 146307030 Common - azoreductase Pmen_2002 99 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 146308448 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Pmen_3429 62 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 146305405 Common - RNA-binding S4 domain protein Pmen_0365 98 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 146307925 Common alaS alanyl-tRNA synthetase Pmen_2903 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 146308629 Common - dihydropteroate synthase Pmen_3614 217 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 146309535 Common - hypothetical protein Pmen_4521 3 None None None 146308224 Common - transcriptional regulator, Fis family Pmen_3204 168 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 146309506 Pathogen - hypothetical protein Pmen_4492 1 None None None 146308876 Common - hypothetical protein Pmen_3862 1 None None None 146307269 Common - high-affinity nickel-transporter Pmen_2243 27 COG2215 COG2215, ABC-type uncharacterized transport system, permease component General function prediction only 146307700 Common - benzoate transporter Pmen_2678 59 COG3135 BenE, Uncharacterized protein involved in benzoate metabolism Secondary metabolites biosynthesis, transport, and catabolism 146305168 Common - transcriptional regulator, LysR family Pmen_0127 176 COG0583 LysR, Transcriptional regulator Transcription 146309620 Common - F0F1 ATP synthase subunit beta Pmen_4607 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 146305377 Common - Agmatine deiminase Pmen_0337 87 COG2957 COG2957, Peptidylarginine deiminase and related enzymes Amino acid transport and metabolism 146305427 Common - NADH dehydrogenase (ubiquinone), 24 kDa subunit Pmen_0387 156 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 146307473 Common - ATPase associated with various cellular activities, AAA_3 Pmen_2450 171 COG0714 COG0714, MoxR-like ATPases General function prediction only 146309573 Common - TRAP transporter, 4TM/12TM fusion protein Pmen_4559 133 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 146305841 Common - TonB-dependent receptor Pmen_0806 129 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 146306485 Common - pseudouridine synthase Pmen_1453 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 146309202 Common - hypothetical protein Pmen_4188 9 None None None 146309489 Common - Carbonate dehydratase Pmen_4475 155 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 146305165 Common - extracellular solute-binding protein, family 1 Pmen_0124 134 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 146307383 Common - hypothetical protein Pmen_2358 46 COG4061 MtrC, Tetrahydromethanopterin S-methyltransferase, subunit C Coenzyme metabolism 146308820 Common - 3-methyladenine DNA glycosylase Pmen_3805 54 COG2094 Mpg, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 146307253 Common - transcriptional regulator, PadR-like family Pmen_2227 16 COG1695 COG1695, Predicted transcriptional regulators Transcription 146305298 Common - Mg chelatase, subunit ChlI Pmen_0257 192 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 146306428 Common - diguanylate cyclase Pmen_1396 171 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 146305840 Common - TonB-dependent siderophore receptor Pmen_0805 117 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 146306762 Common - two component transcriptional regulator, winged helix family Pmen_1731 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 146309601 Common - cobalamin biosynthesis protein CobW Pmen_4587 123 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 146307460 Common - OmpA/MotB domain protein Pmen_2437 137 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 146308370 Common - efflux transporter, RND family, MFP subunit Pmen_3351 154 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 146306865 Common - PHP C-terminal domain protein Pmen_1834 130 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 146306505 Common - signal peptidase I Pmen_1473 209 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 146305698 Common - HupE/UreJ protein Pmen_0663 46 COG2370 HupE, Hydrogenase/urease accessory protein Posttranslational modification, protein turnover, chaperones 146305216 Common - multi-sensor signal transduction histidine kinase Pmen_0175 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 146308185 Common - hypothetical protein Pmen_3165 72 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 146306368 Common - ketosteroid isomerase-like protein Pmen_1336 13 COG4319 COG4319, Ketosteroid isomerase homolog Function unknown 146308830 Common - response regulator receiver protein Pmen_3815 207 COG4566 TtrR, Response regulator Signal transduction mechanisms 146308957 Common - cAMP-regulatory protein Pmen_3943 163 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 146305743 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase Pmen_0708 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 146307400 Common - hypothetical protein Pmen_2377 41 COG1553 DsrE, Uncharacterized conserved protein involved in intracellular sulfur reduction Inorganic ion transport and metabolism 146305475 Common - OmpW family protein Pmen_0436 69 COG3047 OmpW, Outer membrane protein W Cell envelope biogenesis, outer membrane 146306895 Pathogen - hypothetical protein Pmen_1864 1 None None None 146307449 Common - TRAP dicarboxylate transporter, DctP subunit Pmen_2426 97 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 146309046 Common - HipA domain protein Pmen_4032 51 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 146306243 Common - protein of unknown function DUF112, transmembrane Pmen_1211 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 146307759 Common - excinuclease ABC subunit B Pmen_2737 226 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 146305624 Common - glycosyl transferase, group 1 Pmen_0587 211 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 146305890 Common gatC aspartyl/glutamyl-tRNA amidotransferase subunit C Pmen_0855 149 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 146305580 Common - Fimbrial assembly family protein Pmen_0543 39 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 146307727 Common - alpha/beta hydrolase fold Pmen_2705 200 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 146309482 Common - extracellular solute-binding protein, family 1 Pmen_4468 99 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 146306221 Common - multi-sensor hybrid histidine kinase Pmen_1189 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146309195 Common - Calcium/calmodulin dependent protein kinase II, association-domain protein Pmen_4181 19 COG4875 COG4875, Uncharacterized protein conserved in bacteria with a cystatin-like fold Function unknown 146308286 Common - D-serine dehydratase Pmen_3266 47 COG3048 DsdA, D-serine dehydratase Amino acid transport and metabolism 146307039 Common - glutamine amidotransferase Pmen_2011 72 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 146308719 Common - putative transcriptional regulator, MerR family Pmen_3704 118 COG0789 SoxR, Predicted transcriptional regulators Transcription 146306127 Common - polar amino acid ABC transporter, inner membrane subunit Pmen_1093 153 COG4215 ArtQ, ABC-type arginine transport system, permease component Amino acid transport and metabolism 146307769 Common zipA cell division protein ZipA Pmen_2747 47 COG3115 ZipA, Cell division protein Cell division and chromosome partitioning 146306920 Common - flavoprotein involved in K+ transport-like protein Pmen_1890 81 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 146306321 Common - DTW domain containing protein Pmen_1289 35 COG3148 COG3148, Uncharacterized conserved protein Function unknown 146305877 Common - Cupin 2, conserved barrel domain protein Pmen_0842 83 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 146308451 Common - Cobyrinic acid a,c-diamide synthase Pmen_3433 191 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 146306306 Common - MotA/TolQ/ExbB proton channel Pmen_1274 142 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 146306746 Common - beta-lactamase domain protein Pmen_1715 43 COG2015 COG2015, Alkyl sulfatase and related hydrolases Secondary metabolites biosynthesis, transport, and catabolism 146306289 Common - hypothetical protein Pmen_1257 1 None None None 146307964 Common - Rhomboid family protein Pmen_2942 25 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 146305090 Common - type III secretion protein, YscU/HrpY family Pmen_0049 129 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 146308652 Common - IS66 Orf2 family protein Pmen_3637 50 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 146305657 Common - Rhodanese domain protein Pmen_0622 143 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 146306548 Common - major facilitator superfamily MFS_1 Pmen_1517 34 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 146307104 Common - alpha-L-glutamate ligase-like protein Pmen_2076 19 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 146305318 Common - argininosuccinate lyase Pmen_0277 233 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 146308334 Common sbcB exonuclease I Pmen_3314 51 COG2925 SbcB, Exonuclease I DNA replication, recombination, and repair 146308460 Common - transcriptional regulator, GntR family Pmen_3443 138 COG1802 GntR, Transcriptional regulators Transcription 146305055 Common glyS glycyl-tRNA synthetase subunit beta Pmen_0013 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 146306295 Common - putative cold-shock DNA-binding domain protein Pmen_1263 179 COG1278 CspC, Cold shock proteins Transcription 146306650 Common - ribonuclease, Rne/Rng family Pmen_1619 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 146307999 Common - hypothetical protein Pmen_2977 4 None None None 146306059 Common algL poly(beta-D-mannuronate) lyase Pmen_1024 4 None None None 146307868 Common flgF flagellar basal body rod protein FlgF Pmen_2846 120 COG4787 FlgF, Flagellar basal body rod protein Cell motility and secretion 146308908 Common rplF 50S ribosomal protein L6 Pmen_3894 239 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 146305293 Common - hypothetical protein Pmen_0252 4 None None None 146308857 Common - alpha/beta hydrolase fold Pmen_3843 85 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 146308533 Common secD preprotein translocase subunit SecD Pmen_3518 214 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 146306141 Common - ornithine carbamoyltransferase Pmen_1107 239 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 146307516 Common - thioesterase superfamily protein Pmen_2493 26 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 146308794 Common - tRNA-i(6)A37 thiotransferase enzyme MiaB Pmen_3779 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 146308669 Common - metal-dependent hydrolase-like protein Pmen_3654 26 COG3687 COG3687, Predicted metal-dependent hydrolase General function prediction only 146309317 Common - band 7 protein Pmen_4303 216 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 146306090 Common ipk 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase Pmen_1056 191 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 146307680 Common - hypothetical protein Pmen_2658 5 None None None 146308416 Common - hypothetical protein Pmen_3397 14 None None None 146306514 Common - putative methyltransferase Pmen_1482 48 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 146308825 Common - MaoC domain protein dehydratase Pmen_3810 82 COG2030 MaoC, Acyl dehydratase Lipid metabolism 146306386 Common - alpha/beta hydrolase fold Pmen_1354 15 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 146305328 Common - putative CheA signal transduction histidine kinase Pmen_0287 1 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 146309269 Common hisH imidazole glycerol phosphate synthase subunit HisH Pmen_4255 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 146306347 Common - protein of unknown function DUF1232 Pmen_1315 20 COG3339 COG3339, Uncharacterized conserved protein Function unknown 146307165 Common - protein of unknown function DUF1311 Pmen_2138 5 COG3755 COG3755, Uncharacterized protein conserved in bacteria Function unknown 146306378 Common - glycine cleavage system protein H Pmen_1346 185 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 146309431 Common fliF flagellar MS-ring protein Pmen_4417 124 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 146306056 Common - hypothetical protein Pmen_1021 4 None None None 146307522 Common - succinyl-CoA synthetase subunit alpha Pmen_2499 217 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 146306168 Common - protein of unknown function DUF1302 Pmen_1134 18 None None None 146308329 Common - methyl-accepting chemotaxis sensory transducer Pmen_3309 146 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146305140 Common - hypothetical protein Pmen_0099 1 None None None 146309309 Common - TRAP dicarboxylate transporter, DctP subunit Pmen_4295 99 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 146306986 Common - hypothetical protein Pmen_1958 15 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 146308061 Common lpxB lipid-A-disaccharide synthase Pmen_3040 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 146309024 Common - Organic solvent tolerance protein Pmen_4010 123 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 146305408 Common - phosphoenolpyruvate carboxykinase Pmen_0368 97 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 146306698 Common - hypothetical protein Pmen_1667 2 None None None 146307417 Common clpS ATP-dependent Clp protease adaptor protein ClpS Pmen_2394 124 COG2127 COG2127, Uncharacterized conserved protein Function unknown 146307653 Common - OsmC family protein Pmen_2630 97 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 146309363 Pathogen - hypothetical protein Pmen_4349 1 None None None 146305150 Pathogen - hypothetical protein Pmen_0109 1 None None None 146307480 Common - protein of unknown function UPF0118 Pmen_2457 113 COG0628 PerM, Predicted permease General function prediction only 146309341 Common - chromate transporter, chromate ion transporter (CHR) family Pmen_4327 115 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 146306628 Common - Na(+)-translocating NADH-quinone reductase subunit C Pmen_1597 47 COG2869 NqrC, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC Energy production and conversion 146307303 Common - malto-oligosyltrehalose trehalohydrolase Pmen_2278 165 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 146309558 Common - DNA polymerase III subunit epsilon Pmen_4544 133 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 146309142 Common - sarcosine oxidase, gamma subunit family Pmen_4128 31 COG4583 COG4583, Sarcosine oxidase gamma subunit Amino acid transport and metabolism 146307757 Common - secretion protein HlyD family protein Pmen_2735 156 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 146306824 Common - beta-lactamase domain protein Pmen_1793 28 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 146308775 Common - CRISPR-associated protein, Cse1 family Pmen_3760 21 None None None 146308878 Common - ABC transporter related Pmen_3864 248 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 146307144 Pathogen - hypothetical protein Pmen_2116 1 None None None 146307844 Common fliI flagellum-specific ATP synthase Pmen_2822 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 146307773 Common - molybdopterin dehydrogenase, FAD-binding Pmen_2751 122 COG4630 XdhA, Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A Nucleotide transport and metabolism 146306228 Common - regulator of RNA terminal phosphate cyclase Pmen_1196 162 COG4650 RtcR, Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain Transcription / Signal transduction mechanisms 146308685 Common - protein of unknown function DUF159 Pmen_3670 83 COG2135 COG2135, Uncharacterized conserved protein Function unknown 146307660 Pathogen - Antibiotic biosynthesis monooxygenase Pmen_2637 1 COG1359 COG1359, Uncharacterized conserved protein Function unknown 146309257 Common - preprotein translocase subunit SecB Pmen_4243 107 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 146308899 Common rpsD 30S ribosomal protein S4 Pmen_3885 221 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 146307183 Common - hypothetical protein Pmen_2156 9 None None None 146308548 Common - hypothetical protein Pmen_3533 9 COG4519 COG4519, Uncharacterized protein conserved in bacteria Function unknown 146305416 Common - aldo/keto reductase Pmen_0376 168 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 146308278 Common - hypothetical protein Pmen_3258 1 None None None 146307457 Common - surface antigen (D15) Pmen_2434 129 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 146306356 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Pmen_1324 246 COG3634 AhpF, Alkyl hydroperoxide reductase, large subunit Posttranslational modification, protein turnover, chaperones 146309310 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Pmen_4296 30 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 146309396 Common - hypothetical protein Pmen_4382 10 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 146309546 Common - alpha/beta hydrolase fold Pmen_4532 44 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 146308073 Common tsf elongation factor Ts Pmen_3052 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 146305435 Common - beta-ketoacyl synthase Pmen_0395 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 146306731 Common - sodium:neurotransmitter symporter Pmen_1700 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 146308549 Common - Citrate transporter Pmen_3534 145 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 146308835 Common - acetyl-CoA acetyltransferase Pmen_3820 179 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 146306856 Common - helix-turn-helix- domain containing protein, AraC type Pmen_1825 85 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 146307102 Common - short chain dehydrogenase Pmen_2074 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 146306783 Common - cob(II)yrinic acid a,c-diamide reductase Pmen_1752 112 COG0778 NfnB, Nitroreductase Energy production and conversion 146306642 Common - DNA internalization-related competence protein ComEC/Rec2 Pmen_1611 140 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 146306113 Common - hypothetical protein Pmen_1079 12 None None None 146306153 Common - hypothetical protein Pmen_1119 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 146305443 Common - response regulator receiver protein Pmen_0403 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 146308080 Common - Tetrahydrodipicolinate N-succinyltransferase-like protein Pmen_3059 42 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 146306806 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Pmen_1775 224 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 146307942 Common - general secretion pathway protein J Pmen_2920 23 COG4795 PulJ, Type II secretory pathway, component PulJ Intracellular trafficking and secretion 146308952 Common - short-chain dehydrogenase/reductase SDR Pmen_3938 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 146307938 Common - cationic amino acid ABC transporter, periplasmic binding protein Pmen_2916 173 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146308523 Common hscB co-chaperone HscB Pmen_3508 59 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 146307331 Common - short-chain dehydrogenase/reductase SDR Pmen_2306 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 146306120 Common - Water Stress and Hypersensitive response Pmen_1086 16 COG5608 COG5608, Conserved secreted protein Function unknown 146308229 Common - transcriptional regulator, LysR family Pmen_3209 137 COG0583 LysR, Transcriptional regulator Transcription 146308029 Common - hypothetical protein Pmen_3007 27 COG3171 COG3171, Uncharacterized protein conserved in bacteria Function unknown 146305694 Common - protein of unknown function DUF808 Pmen_0659 61 COG2354 COG2354, Uncharacterized protein conserved in bacteria Function unknown 146306331 Common - MotA/TolQ/ExbB proton channel Pmen_1299 94 COG1291 MotA, Flagellar motor component Cell motility and secretion 146306653 Common - signal peptide peptidase SppA, 36K type Pmen_1622 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 146308492 Common - hypothetical protein Pmen_3475 6 COG4583 COG4583, Sarcosine oxidase gamma subunit Amino acid transport and metabolism 146307495 Common - hypothetical protein Pmen_2472 3 None None None 146305985 Common rpsT 30S ribosomal protein S20 Pmen_0950 144 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 146308989 Common - HNH endonuclease Pmen_3975 25 None None None 146309042 Common - RNA polymerase sigma factor RpoD Pmen_4028 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 146308291 Common - hypothetical protein Pmen_3271 19 None None None 146307989 Common - protein of unknown function DUF1311 Pmen_2967 4 COG3755 COG3755, Uncharacterized protein conserved in bacteria Function unknown 146307265 Common - hypothetical protein Pmen_2239 12 COG4982 COG4982, 3-oxoacyl- acyl-carrier protein 146307918 Common - short-chain dehydrogenase/reductase SDR Pmen_2896 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 146305977 Common - methylated-DNA-(protein)-cysteine S-methyltransferase Pmen_0942 25 COG3695 COG3695, Predicted methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 146305266 Common - diguanylate cyclase with PAS/PAC sensor Pmen_0225 183 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 146305921 Common - hypothetical protein Pmen_0886 10 COG5266 CbiK, ABC-type Co2+ transport system, periplasmic component Inorganic ion transport and metabolism 146305951 Common - Peptidoglycan glycosyltransferase Pmen_0916 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 146306004 Common - pseudouridine synthase, RluA family Pmen_0969 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 146307005 Common infC translation initiation factor IF-3 Pmen_1977 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 146305749 Common - acetyl-CoA carboxylase biotin carboxyl carrier protein subunit Pmen_0714 183 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 146305046 Common gyrB DNA gyrase subunit B Pmen_0004 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 146306148 Common - Lysine exporter protein (LYSE/YGGA) Pmen_1114 72 COG1279 COG1279, Lysine efflux permease General function prediction only 146309513 Common - transcriptional regulator, LysR family Pmen_4499 93 COG0583 LysR, Transcriptional regulator Transcription 146307723 Common - putative transcriptional regulator, GntR family Pmen_2701 225 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 146307407 Common - seryl-tRNA synthetase Pmen_2384 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 146305713 Common - iron-containing alcohol dehydrogenase Pmen_0678 173 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 146307156 Common - hypothetical protein Pmen_2129 23 COG4394 COG4394, Uncharacterized protein conserved in bacteria Function unknown 146308178 Common - hypothetical protein Pmen_3158 9 None None None 146306662 Common - 4-amino-4-deoxychorismate lyase Pmen_1631 188 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 146306564 Common - hypothetical protein Pmen_1533 1 None None None 146307462 Common - acyl-CoA dehydrogenase domain protein Pmen_2439 149 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 146309262 Common - carboxyl-terminal protease Pmen_4248 182 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 146305931 Common - hypothetical protein Pmen_0896 7 None None None 146306550 Common - protein tyrosine phosphatase Pmen_1519 182 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 146306875 Common - phosphoglycolate phosphatase Pmen_1844 197 COG0546 Gph, Predicted phosphatases General function prediction only 146305935 Common - aldo/keto reductase Pmen_0900 196 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 146308635 Common carB carbamoyl phosphate synthase large subunit Pmen_3620 236 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 146306534 Common - Antibiotic biosynthesis monooxygenase Pmen_1502 27 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 146307192 Common - hypothetical protein Pmen_2165 1 None None None 146305943 Common - transport-associated Pmen_0908 60 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 146305425 Pathogen - 17 kDa surface antigen Pmen_0385 1 None None None 146309063 Common - coenzyme A transferase Pmen_4049 106 COG4670 COG4670, Acyl CoA:acetate/3-ketoacid CoA transferase Lipid metabolism 146308912 Common rplX 50S ribosomal protein L24 Pmen_3898 212 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 146306003 Common - DNA uptake lipoprotein-like protein Pmen_0968 122 COG4105 ComL, DNA uptake lipoprotein General function prediction only 146308262 Common - hypothetical protein Pmen_3242 1 None None None 146305671 Common - GTP-binding protein, HSR1-related Pmen_0636 226 COG2262 HflX, GTPases General function prediction only 146308067 Common - putative membrane-associated zinc metalloprotease Pmen_3046 209 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 146306721 Common - hypothetical protein Pmen_1690 18 None None None 146306559 Common - transcriptional regulator, LysR family Pmen_1528 149 COG0583 LysR, Transcriptional regulator Transcription 146309289 Common - acyltransferase 3 Pmen_4275 104 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 146307783 Common - protein of unknown function DUF989 Pmen_2761 39 COG3748 COG3748, Predicted membrane protein Function unknown 146307201 Common - methyl-accepting chemotaxis sensory transducer Pmen_2174 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146308288 Common - Beta-xylosidase-like protein Pmen_3268 12 COG3664 XynB, Beta-xylosidase Carbohydrate transport and metabolism 146305873 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Pmen_0838 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 146306434 Common - electron transport complex protein RnfC Pmen_1402 95 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 146309478 Common - transcriptional regulator, AraC family Pmen_4464 83 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 146307509 Pathogen - hypothetical protein Pmen_2486 4 None None None 146307128 Common - thioesterase-like protein Pmen_2100 20 COG0824 FcbC, Predicted thioesterase General function prediction only 146308122 Common - acyl-CoA dehydrogenase domain protein Pmen_3101 149 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 146307947 Common - general secretory pathway protein E Pmen_2925 217 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 146306864 Common - YciI-like protein Pmen_1833 54 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 146307434 Common - hypothetical protein Pmen_2411 14 None None None 146305134 Common - hypothetical protein Pmen_0093 30 COG4104 COG4104, Uncharacterized conserved protein Function unknown 146309131 Pathogen - hypothetical protein Pmen_4117 1 None None None 146308099 Pathogen - hypothetical protein Pmen_3078 1 None None None 146309198 Common - multi-sensor hybrid histidine kinase Pmen_4184 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146306401 Common - beta-lactamase domain protein Pmen_1369 82 COG2015 COG2015, Alkyl sulfatase and related hydrolases Secondary metabolites biosynthesis, transport, and catabolism 146305814 Common - protein of unknown function DUF1631 Pmen_0779 21 None None None 146305486 Common - S-adenosyl-L-homocysteine hydrolase Pmen_0449 177 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 146307764 Common - hypothetical protein Pmen_2742 1 None None None 146308992 Common - virulence-associated E family protein Pmen_3978 57 COG5545 COG5545, Predicted P-loop ATPase and inactivated derivatives General function prediction only 146306501 Common - sigma E regulatory protein, MucB/RseB Pmen_1469 48 COG3026 RseB, Negative regulator of sigma E activity Signal transduction mechanisms 146305653 Common - phosphoserine phosphatase SerB Pmen_0618 162 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 146307836 Common fliN flagellar motor switch protein Pmen_2814 122 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 146306637 Common - type IV pilus assembly PilZ Pmen_1606 8 None None None 146305240 Common - malate synthase G Pmen_0199 81 COG2225 AceB, Malate synthase Energy production and conversion 146306253 Common - ABC-2 type transporter Pmen_1221 179 COG1511 COG1511, Predicted membrane protein Function unknown 146307045 Common - transcriptional regulator, LysR family Pmen_2017 136 COG0583 LysR, Transcriptional regulator Transcription 146307551 Common - hypothetical protein Pmen_2528 16 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 146308530 Common - Inositol-phosphate phosphatase Pmen_3515 202 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 146306310 Common - OmpA domain protein Pmen_1278 154 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 146307416 Common - ATP-dependent Clp protease, ATP-binding subunit clpA Pmen_2393 218 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 146308645 Common - cyclase/dehydrase Pmen_3630 102 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 146306803 Common - Strictosidine synthase Pmen_1772 39 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 146306525 Common - MaoC domain protein dehydratase Pmen_1493 94 COG2030 MaoC, Acyl dehydratase Lipid metabolism 146307814 Common - hypothetical protein Pmen_2792 11 None None None 146305907 Common - OstA family protein Pmen_0872 64 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 146305191 Common - protoheme IX farnesyltransferase Pmen_0150 169 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 146305394 Common - N-acetylglutamate synthase Pmen_0354 190 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 146305467 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Pmen_0427 62 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 146305454 Common - methylmalonate-semialdehyde dehydrogenase Pmen_0414 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 146308298 Pathogen - hypothetical protein Pmen_3278 1 None None None 146308259 Common - Non-specific serine/threonine protein kinase Pmen_3239 139 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 146307276 Common - hypothetical protein Pmen_2250 17 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 146307859 Common - Nucleotidyl transferase Pmen_2837 14 COG1213 COG1213, Predicted sugar nucleotidyltransferases Cell envelope biogenesis, outer membrane 146308337 Common - protein of unknown function DUF95, transmembrane Pmen_3317 35 COG1300 SpoIIM, Uncharacterized membrane protein Function unknown 146307426 Common - Cupin 4 family protein Pmen_2403 58 COG2850 COG2850, Uncharacterized conserved protein Function unknown 146307845 Common fliH flagellar assembly protein H Pmen_2823 71 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 146308510 Common - putative aminotransferase Pmen_3495 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 146309497 Common - (2Fe-2S)-binding domain protein Pmen_4483 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 146305383 Common - putative aminotransferase Pmen_0343 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 146309030 Common glpE thiosulfate sulfurtransferase Pmen_4016 118 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 146308819 Common - O-Methyltransferase involved in polyketide biosynthesis-like protein Pmen_3804 4 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 146307823 Common - chemotaxis-specific methylesterase Pmen_2801 211 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 146307827 Common fliA flagellar biosynthesis sigma factor Pmen_2805 209 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 146307977 Common - asparagine synthase (glutamine-hydrolyzing) Pmen_2955 156 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 146308158 Common - Maltose operon periplasmic Pmen_3138 17 None None None 146307524 Common - dihydrolipoamide dehydrogenase Pmen_2501 247 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 146308150 Common malG maltose transporter permease Pmen_3130 161 COG3833 MalG, ABC-type maltose transport systems, permease component Carbohydrate transport and metabolism 146308699 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase Pmen_3684 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 146307990 Pathogen - hypothetical protein Pmen_2968 1 None None None 146308694 Common - gamma-glutamyl kinase Pmen_3679 190 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 146307139 Pathogen - hypothetical protein Pmen_2111 1 None None None 146308245 Common - transcriptional regulator, LysR family Pmen_3225 105 COG0583 LysR, Transcriptional regulator Transcription 146305230 Common - flagellar hook-length control protein Pmen_0189 10 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 146307984 Common - PP-loop domain protein Pmen_2962 164 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 146305296 Common - multidrug efflux protein NorA Pmen_0255 150 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 146306684 Common - protein of unknown function UPF0118 Pmen_1653 136 COG0628 PerM, Predicted permease General function prediction only 146308613 Common - conserved hypothetical protein 95 Pmen_3598 112 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 146309282 Common - hypothetical protein Pmen_4268 3 None None None 146306755 Common - AMP-dependent synthetase and ligase Pmen_1724 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 146308317 Common - periplasmic lipoprotein-like protein Pmen_3297 25 COG3489 COG3489, Predicted periplasmic lipoprotein General function prediction only 146305896 Common - membrane protein-like protein Pmen_0861 56 COG3164 COG3164, Predicted membrane protein Function unknown 146305705 Common - hypothetical protein Pmen_0670 1 None None None 146308517 Common - type IV pilus biogenesis/stability protein PilW Pmen_3502 47 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 146307779 Common - Transthyretin Pmen_2757 63 COG2351 COG2351, Transthyretin-like protein General function prediction only 146309551 Common - transcriptional regulator, TraR/DksA family Pmen_4537 126 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 146309529 Common - TRAP dicarboxylate transporter- DctP subunit Pmen_4515 107 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 146309162 Common - twitching motility protein Pmen_4148 210 COG5008 PilU, Tfp pilus assembly protein, ATPase PilU Cell motility and secretion / Intracellular trafficking and secretion 146306781 Common - cob(I)yrinic acid a,c-diamide adenosyltransferase Pmen_1750 142 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 146308654 Common - ATPase AAA-2 domain protein Pmen_3639 224 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 146305666 Common - protein of unknown function UPF0079 Pmen_0631 205 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 146305902 Common - hypothetical protein Pmen_0867 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 146309161 Common - hypothetical protein Pmen_4147 39 None None None 146305364 Common - hypothetical protein Pmen_0323 10 None None None 146306606 Common - Lytic transglycosylase, catalytic Pmen_1575 169 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 146307399 Common - protein of unknown function UPF0005 Pmen_2376 103 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 146305571 Common - Sporulation domain protein Pmen_0534 27 COG3087 FtsN, Cell division protein Cell division and chromosome partitioning 146306408 Common - Extracellular ligand-binding receptor Pmen_1376 99 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 146308250 Common mnmC 5-methylaminomethyl-2-thiouridine methyltransferase Pmen_3230 94 COG4121 COG4121, Uncharacterized conserved protein Function unknown 146308789 Common - glutamate-1-semialdehyde aminotransferase Pmen_3774 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 146307323 Common - hypothetical protein Pmen_2298 1 None None None 146307934 Common - helix-turn-helix- domain containing protein, AraC type Pmen_2912 145 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 146308713 Common - uracil-xanthine permease Pmen_3698 128 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 146305239 Common - L-lactate permease Pmen_0198 104 COG1620 LldP, L-lactate permease Energy production and conversion 146308382 Common - OmpA/MotB domain protein Pmen_3363 172 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 146305764 Common - MATE efflux family protein Pmen_0729 71 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 146306239 Common - hypothetical protein Pmen_1207 1 None None None 146307502 Common - lipopolysaccharide kinase Pmen_2479 7 None None None 146307244 Common - copper resistance B precursor Pmen_2217 43 COG3667 PcoB, Uncharacterized protein involved in copper resistance Inorganic ion transport and metabolism 146308129 Common acsA acetyl-CoA synthetase Pmen_3109 215 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 146307780 Common - Chitin deacetylase Pmen_2758 95 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 146306266 Common - septum site-determining protein MinD Pmen_1234 138 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 146308402 Common - Superfamily I DNA and RNA helicase and helicase subunits-like protein Pmen_3383 91 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 146308661 Common - phospholipid/glycerol acyltransferase Pmen_3646 31 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 146309393 Common - Phosphomannomutase Pmen_4379 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 146305270 Common - putative metal dependent phosphohydrolase Pmen_0229 109 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 146305062 Pathogen - hypothetical protein Pmen_0020 1 None None None 146305347 Common - extracellular solute-binding protein, family 3 Pmen_0306 169 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146308057 Common - tRNA(Ile)-lysidine synthetase Pmen_3036 206 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 146305630 Common - Mig-14 family protein Pmen_0595 5 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 146305975 Common - MscS Mechanosensitive ion channel Pmen_0940 197 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 146307432 Common - hypothetical protein Pmen_2409 3 None None None 146306814 Common - histidine triad (HIT) protein Pmen_1783 189 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 146307243 Common - hypothetical protein Pmen_2216 20 None None None 146307410 Common lolA outer-membrane lipoprotein carrier protein Pmen_2387 89 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 146308581 Common - ornithine cyclodeaminase/mu-crystallin Pmen_3566 33 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 146309241 Common - SdiA-regulated domain protein Pmen_4227 11 COG3204 COG3204, Uncharacterized protein conserved in bacteria Function unknown 146309335 Common - binding-protein-dependent transport systems inner membrane component Pmen_4321 195 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 146306206 Common - two component heavy metal response transcriptional regulator, winged helix family Pmen_1174 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 146307347 Common - uncharacterised conserved protein UCP028301 Pmen_2322 49 COG3516 COG3516, Uncharacterized protein conserved in bacteria Function unknown 146306947 Common - Transglutaminase-like enzymes putative cysteine protease-like protein Pmen_1918 22 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 146305887 Common - rare lipoprotein A Pmen_0852 137 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 146308046 Common truD tRNA pseudouridine synthase D Pmen_3025 83 COG0585 COG0585, Uncharacterized conserved protein Function unknown 146309272 Common - AsmA family protein Pmen_4258 57 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 146308240 Common - hypothetical protein Pmen_3220 5 None None None 146306899 Common - glycosyl transferase, group 1 Pmen_1869 89 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 146309003 Pathogen - hypothetical protein Pmen_3989 1 None None None 146307082 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Pmen_2054 168 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 146309271 Common - FAD dependent oxidoreductase Pmen_4257 100 COG0579 COG0579, Predicted dehydrogenase General function prediction only 146306779 Common - Caffeoyl-CoA O-methyltransferase Pmen_1748 96 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 146308035 Common - hypothetical protein Pmen_3013 1 None None None 146308573 Common - polar amino acid ABC transporter, inner membrane subunit Pmen_3558 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 146309629 Common - Cobyrinic acid a,c-diamide synthase Pmen_4616 229 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 146306025 Common - hypothetical protein Pmen_0990 1 COG5373 COG5373, Predicted membrane protein Function unknown 146305089 Common - type III secretion protein SpaR/YscT/HrcT Pmen_0048 38 COG4791 EscT, Type III secretory pathway, component EscT Intracellular trafficking and secretion 146307056 Common - acetyl-CoA synthetase Pmen_2028 204 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 146308753 Common - Redoxin domain protein Pmen_3738 157 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 146308782 Common - periplasmic binding protein Pmen_3767 42 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 146306888 Common - UDP-glucose/GDP-mannose dehydrogenase Pmen_1857 202 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 146306993 Common pqqA coenzyme PQQ synthesis protein PqqA Pmen_1965 1 None None None 146309373 Common - TRAP dicarboxylate transporter, DctM subunit Pmen_4359 122 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 146309384 Common - fatty acid desaturase Pmen_4370 5 COG3239 DesA, Fatty acid desaturase Lipid metabolism 146305483 Pathogen - hypothetical protein Pmen_0446 1 None None None 146307220 Common - ICC-like phosphoesterase-like protein Pmen_2193 50 COG1407 COG1407, Predicted ICC-like phosphoesterases General function prediction only 146305249 Common flgD flagellar basal body rod modification protein Pmen_0208 103 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 146306751 Common - protein of unknown function DUF1302 Pmen_1720 18 None None None 146309250 Common - hypothetical protein Pmen_4236 1 None None None 146308377 Common - 5'-nucleotidase, lipoprotein e(P4) family Pmen_3358 24 COG2503 COG2503, Predicted secreted acid phosphatase General function prediction only 146309417 Common - Rubredoxin-type Fe(Cys)4 protein Pmen_4403 115 COG1773 COG1773, Rubredoxin Energy production and conversion 146306188 Common - porin, LamB type Pmen_1154 26 COG4580 LamB, Maltoporin (phage lambda and maltose receptor) Carbohydrate transport and metabolism 146308967 Common - hypothetical protein Pmen_3953 2 None None None 146309039 Common - putative metalloendopeptidase, glycoprotease family Pmen_4025 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 146306493 Common - extracellular solute-binding protein, family 3 Pmen_1461 26 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146309248 Common - hypothetical protein Pmen_4234 2 None None None 146305077 Common - transposase IS66 Pmen_0036 67 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 146307992 Common - AMP-dependent synthetase and ligase Pmen_2970 217 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 146307864 Common flgJ peptidoglycan hydrolase Pmen_2842 75 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 146307566 Common - helix-turn-helix- domain containing protein, AraC type Pmen_2543 73 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 146308201 Common - FHA domain containing protein Pmen_3181 33 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 146308611 Common - hypothetical protein Pmen_3596 25 COG3662 COG3662, Uncharacterized protein conserved in bacteria Function unknown 146307130 Common - hypothetical protein Pmen_2102 7 None None None 146309126 Pathogen - hypothetical protein Pmen_4112 1 None None None 146309105 Common - transcriptional regulator, ModE family Pmen_4091 55 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 146308983 Common - hypothetical protein Pmen_3969 10 None None None 146309016 Common - extracellular solute-binding protein, family 1 Pmen_4002 91 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 146306468 Common - pyridoxamine 5'-phosphate oxidase Pmen_1436 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 146306268 Common - lipid A biosynthesis lauroyl acyltransferase Pmen_1236 114 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 146305926 Common - bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein Pmen_0891 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 146306103 Common - short-chain dehydrogenase/reductase SDR Pmen_1069 222 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 146308770 Common - CRISPR-associated protein Cas1 Pmen_3755 46 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 146305770 Common - diguanylate cyclase Pmen_0735 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 146308676 Common - acyl-CoA synthetase Pmen_3661 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 146308711 Common - transcriptional regulator, LysR family Pmen_3696 99 COG0583 LysR, Transcriptional regulator Transcription 146308089 Common - hypothetical protein Pmen_3068 5 None None None 146307533 Common - protein of unknown function UPF0153 Pmen_2510 37 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 146309508 Common - major facilitator superfamily MFS_1 Pmen_4494 82 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 146306440 Common dcd deoxycytidine triphosphate deaminase Pmen_1408 151 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 146309522 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Pmen_4508 95 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 146308526 Common - cysteine desulfurase IscS Pmen_3511 239 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 146306582 Pathogen - hypothetical protein Pmen_1551 1 None None None 146307099 Common nudC NADH pyrophosphatase Pmen_2071 101 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 146306560 Common - short-chain dehydrogenase/reductase SDR Pmen_1529 215 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 146305995 Common - Tfp pilus assembly protein PilW-like protein Pmen_0960 2 COG4966 PilW, Tfp pilus assembly protein PilW Cell motility and secretion / Intracellular trafficking and secretion 146308837 Common - YbaK/prolyl-tRNA synthetase associated region Pmen_3822 89 COG2606 EbsC, Uncharacterized conserved protein Function unknown 146307777 Common - transcriptional regulator, GntR family Pmen_2755 138 COG1802 GntR, Transcriptional regulators Transcription 146309044 Pathogen - hypothetical protein Pmen_4030 1 None None None 146306445 Common - NUDIX hydrolase Pmen_1413 49 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 146307375 Common - protein of unknown function UPF0126 Pmen_2350 133 COG2860 COG2860, Predicted membrane protein Function unknown 146309171 Common - hypothetical protein Pmen_4157 13 None None None 146307732 Common - O-succinylhomoserine sulfhydrylase Pmen_2710 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 146305681 Common rpsR 30S ribosomal protein S18 Pmen_0646 214 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 146309355 Common - molybdate ABC transporter, ATPase subunit Pmen_4341 249 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 146306945 Common - hypothetical protein Pmen_1916 3 None None None 146306962 Common - tRNA-dihydrouridine synthase A Pmen_1933 207 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 146307696 Common - putative FecR Pmen_2674 47 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 146306712 Common - transcriptional regulator, TetR family Pmen_1681 73 COG1309 AcrR, Transcriptional regulator Transcription 146307234 Common - hypothetical protein Pmen_2207 1 None None None 146308762 Common - GCN5-related N-acetyltransferase Pmen_3747 55 COG0456 RimI, Acetyltransferases General function prediction only 146308482 Common - ferredoxin-dependent glutamate synthase Pmen_3465 210 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 146307076 Common - Methenyltetrahydrofolate cyclohydrolase Pmen_2048 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 146309291 Common - virulence factor MVIN family protein Pmen_4277 57 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 146306379 Common - superoxide dismutase, copper/zinc binding Pmen_1347 88 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 146305430 Common - hypothetical protein Pmen_0390 14 None None None 146308964 Pathogen - hypothetical protein Pmen_3950 1 None None None 146307094 Common rnhA ribonuclease H Pmen_2066 176 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 146307579 Common - ErfK/YbiS/YcfS/YnhG family protein Pmen_2556 95 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 146305585 Common aroB 3-dehydroquinate synthase Pmen_0548 210 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 146308765 Common - AMP nucleosidase Pmen_3750 54 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 146307624 Pathogen - Cbb3-type cytochrome oxidase component Pmen_2601 1 COG4736 CcoQ, Cbb3-type cytochrome oxidase, subunit 3 Posttranslational modification, protein turnover, chaperones 146306556 Common - citrate/H+ symporter, CitMHS family Pmen_1525 31 COG2851 CitM, H+/citrate symporter Energy production and conversion 146306748 Common - hypothetical protein Pmen_1717 1 None None None 146309214 Common - spermidine/putrescine ABC transporter ATPase subunit Pmen_4200 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 146306372 Common - 5-carboxymethyl-2-hydroxymuconate isomerase-like protein Pmen_1340 10 COG3232 HpaF, 5-carboxymethyl-2-hydroxymuconate isomerase Amino acid transport and metabolism 146306724 Common - hypothetical protein Pmen_1693 109 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 146307742 Common - aspartate-semialdehyde dehydrogenase Pmen_2720 200 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 146309420 Common - protein of unknown function DUF21 Pmen_4406 215 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 146308734 Common - acyl-CoA thioesterase II Pmen_3719 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 146307634 Common - cytochrome oxidase maturation protein, cbb3-type Pmen_2611 39 COG3197 FixS, Uncharacterized protein, possibly involved in nitrogen fixation Inorganic ion transport and metabolism 146309011 Common - anthranilate synthase component I Pmen_3997 223 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 146305284 Common - protein of unknown function UPF0153 Pmen_0243 10 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 146305351 Common - UbiD family decarboxylase Pmen_0310 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 146308222 Common - aldehyde dehydrogenase Pmen_3202 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 146305727 Common ureC urease subunit alpha Pmen_0692 96 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 146306328 Common - transcriptional regulator, LysR family Pmen_1296 144 COG0583 LysR, Transcriptional regulator Transcription 146307671 Pathogen - hypothetical protein Pmen_2649 1 None None None 146307729 Common - electron transfer flavoprotein beta-subunit Pmen_2707 153 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 146309082 Common - transcriptional regulator, GntR family Pmen_4068 122 COG2188 PhnF, Transcriptional regulators Transcription 146305811 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Pmen_0776 62 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 146306953 Common - hypothetical protein Pmen_1924 1 None None None 146309251 Common - Lysophospholipase-like protein Pmen_4237 53 COG2267 PldB, Lysophospholipase Lipid metabolism 146305415 Pathogen - hypothetical protein Pmen_0375 1 None None None 146309111 Common - putative CBS domain and cyclic nucleotide-regulated nucleotidyltransferase Pmen_4097 134 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 146306183 Common - integral membrane sensor signal transduction histidine kinase Pmen_1149 213 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146307851 Common - sigma54 specific transcriptional regulator, Fis family Pmen_2829 170 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 146307689 Common - histidine kinase Pmen_2667 110 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 146305858 Common - Heavy metal transport/detoxification protein Pmen_0823 57 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 146307958 Common - hypothetical protein Pmen_2936 50 COG4447 COG4447, Uncharacterized protein related to plant photosystem II stability/assembly factor General function prediction only 146308679 Common - glycerate dehydrogenase Pmen_3664 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 146306086 Common - translation-associated GTPase Pmen_1052 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 146305755 Common - type I secretion system ATPase Pmen_0720 249 COG4618 ArpD, ABC-type protease/lipase transport system, ATPase and permease components General function prediction only 146307043 Common - dihydropteridine reductase Pmen_2015 52 COG0778 NfnB, Nitroreductase Energy production and conversion 146305136 Common - protein of unknown function DUF879 Pmen_0095 48 COG3519 COG3519, Uncharacterized protein conserved in bacteria Function unknown 146308587 Common - DNA polymerase II Pmen_3572 65 COG0417 PolB, DNA polymerase elongation subunit (family B) DNA replication, recombination, and repair 146309463 Pathogen - hypothetical protein Pmen_4449 1 None None None 146308306 Common - putative transcriptional regulator, MerR family Pmen_3286 55 COG0789 SoxR, Predicted transcriptional regulators Transcription 146305620 Common - lipopolysaccharide kinase Pmen_0583 4 None None None 146309032 Common - hypothetical protein Pmen_4018 71 COG2718 COG2718, Uncharacterized conserved protein Function unknown 146306938 Common - Peroxiredoxin Pmen_1909 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 146306261 Common - globin Pmen_1229 24 COG2346 COG2346, Truncated hemoglobins General function prediction only 146305117 Common - NAD-dependent epimerase/dehydratase Pmen_0076 105 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 146307174 Common - Sulfite reductase (ferredoxin) Pmen_2147 161 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 146307887 Common - periplasmic binding protein Pmen_2865 64 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 146308758 Common - hypothetical protein Pmen_3743 1 None None None 146307121 Common - uroporphyrin-III C-methyltransferase Pmen_2093 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 146305185 Common - cytochrome C oxidase assembly protein Pmen_0144 68 COG3175 COX11, Cytochrome oxidase assembly factor Posttranslational modification, protein turnover, chaperones 146309094 Common - diguanylate cyclase Pmen_4080 173 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 146308141 Pathogen - hypothetical protein Pmen_3121 1 None None None 146307215 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Pmen_2188 154 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 146308741 Common - putative PAS/PAC sensor protein Pmen_3726 20 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 146308562 Common - TRAP-type uncharacterized transport system periplasmic component-like protein Pmen_3547 15 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 146306199 Common - phosphate-selective porin O and P Pmen_1166 20 COG3746 OprP, Phosphate-selective porin Inorganic ion transport and metabolism 146306013 Common - thioredoxin reductase Pmen_0978 247 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 146306472 Common - 17 kDa surface antigen Pmen_1440 7 COG3133 SlyB, Outer membrane lipoprotein Cell envelope biogenesis, outer membrane 146306391 Common - hypothetical protein Pmen_1359 57 COG3665 COG3665, Uncharacterized conserved protein Function unknown 146306690 Common - SirA family protein Pmen_1659 89 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 146305865 Common - hypothetical protein Pmen_0830 1 None None None 146307465 Common - Lytic transglycosylase, catalytic Pmen_2442 94 COG4623 COG4623, Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein Cell envelope biogenesis, outer membrane 146307283 Common - protein of unknown function DUF892 Pmen_2257 21 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 146308735 Common - hypothetical protein Pmen_3720 28 None None None 146309442 Common - L-carnitine dehydratase/bile acid-inducible protein F Pmen_4428 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 146305786 Common - rRNA (guanine-N(2)-)-methyltransferase Pmen_0751 92 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 146309118 Common - hypothetical protein Pmen_4104 3 None None None 146306976 Common - ABC-type branched-chain amino acid transport systems periplasmic component-like protein Pmen_1948 19 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 146307137 Pathogen - hypothetical protein Pmen_2109 1 None None None 146306193 Common - phage transcriptional regulator, AlpA Pmen_1159 44 COG3311 AlpA, Predicted transcriptional regulator Transcription 146308579 Common - peptidase M19, renal dipeptidase Pmen_3564 98 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 146306686 Common - glutathione-dependent formaldehyde-activating, GFA Pmen_1655 62 COG3791 COG3791, Uncharacterized conserved protein Function unknown 146307025 Common - NADPH-dependent FMN reductase Pmen_1997 8 COG0431 COG0431, Predicted flavoprotein General function prediction only 146306735 Common - short-chain dehydrogenase/reductase SDR Pmen_1704 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 146307068 Common - protein of unknown function DUF6, transmembrane Pmen_2040 25 COG2962 RarD, Predicted permeases General function prediction only 146305103 Common - sulphate transporter Pmen_0062 148 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 146305227 Common - flagellar hook-associated 2 domain protein Pmen_0186 90 COG1345 FliD, Flagellar capping protein Cell motility and secretion 146305837 Common - TonB-dependent siderophore receptor Pmen_0802 102 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 146309053 Common - protein of unknown function UPF0057 Pmen_4039 29 COG0401 COG0401, Uncharacterized homolog of Blt101 Function unknown 146305268 Common - aldehyde dehydrogenase Pmen_0227 205 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 146309575 Common - two component, sigma54 specific, transcriptional regulator, Fis family Pmen_4561 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 146307915 Common - pyruvate carboxylase subunit B Pmen_2893 178 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 146309348 Common - Acyl-CoA dehydrogenase, type 2, C-terminal domain Pmen_4334 144 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 146307792 Common - Hydroxypyruvate isomerase Pmen_2770 82 COG3622 Hfi, Hydroxypyruvate isomerase Carbohydrate transport and metabolism 146309327 Common - multi-sensor hybrid histidine kinase Pmen_4313 223 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 146305068 Pathogen - type III secretion apparatus protein, HrpE/YscL family Pmen_0026 2 None None None 146307447 Common - NADH dehydrogenase subunit N Pmen_2424 208 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 146309200 Common - transcriptional regulator, TetR family Pmen_4186 40 COG1309 AcrR, Transcriptional regulator Transcription 146305779 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase Pmen_0744 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 146306487 Common - protein of unknown function DUF112, transmembrane Pmen_1455 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 146308118 Common - SH3, type 3 domain protein Pmen_3097 28 COG3103 COG3103, SH3 domain protein Signal transduction mechanisms 146305847 Common - putative transcriptional regulator, MerR family Pmen_0812 142 COG0789 SoxR, Predicted transcriptional regulators Transcription 146305775 Common - Methyltransferase type 11 Pmen_0740 65 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 146309061 Common - sigma54 specific transcriptional regulator, Fis family Pmen_4047 170 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 146308827 Common - NAD-dependent epimerase/dehydratase Pmen_3812 79 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 146306340 Common - membrane-bound metal-dependent hydrolase Pmen_1308 24 COG1988 COG1988, Predicted membrane-bound metal-dependent hydrolases General function prediction only 146308971 Pathogen - hypothetical protein Pmen_3957 1 None None None 146306546 Common - ThiJ/PfpI domain protein Pmen_1515 38 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 146309627 Common - F0F1 ATP synthase subunit I Pmen_4614 3 COG3312 AtpI, F0F1-type ATP synthase, subunit I Energy production and conversion 146305741 Common - integral membrane sensor hybrid histidine kinase Pmen_0706 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146308554 Common - hypothetical protein Pmen_3539 3 None None None 146305799 Common - protein of unknown function DUF1631 Pmen_0764 21 None None None 146308944 Common - iron-sulfur cluster assembly accessory protein Pmen_3930 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 146306042 Common ilvH acetolactate synthase 3 regulatory subunit Pmen_1007 189 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 146307923 Common - carbon storage regulator, CsrA Pmen_2901 57 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 146309470 Common - protein of unknown function DUF1161 Pmen_4456 6 None None None 146305214 Pathogen - hypothetical protein Pmen_0173 1 None None None 146305828 Common - flavodoxin/nitric oxide synthase Pmen_0793 106 COG0369 CysJ, Sulfite reductase, alpha subunit (flavoprotein) Inorganic ion transport and metabolism 146308980 Pathogen - hypothetical protein Pmen_3966 1 None None None 146307267 Common - hypothetical protein Pmen_2241 1 COG2985 COG2985, Predicted permease General function prediction only 146306133 Common - cyanophycinase Pmen_1099 16 COG4242 CphB, Cyanophycinase and related exopeptidases Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism 146306831 Common - methyl-accepting chemotaxis sensory transducer Pmen_1800 165 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146306707 Common - hypothetical protein Pmen_1676 5 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 146307017 Common - IS66 Orf2 family protein Pmen_1989 50 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 146309004 Pathogen - hypothetical protein Pmen_3990 1 None None None 146305473 Common - transposase IS66 Pmen_0434 67 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 146305163 Common - helix-turn-helix- domain containing protein, AraC type Pmen_0122 91 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 146306893 Common - Adenylyl-sulfate kinase Pmen_1862 145 COG0529 CysC, Adenylylsulfate kinase and related kinases Inorganic ion transport and metabolism 146305053 Common - phospholipid/glycerol acyltransferase Pmen_0011 191 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 146309533 Pathogen - hypothetical protein Pmen_4519 1 None None None 146305110 Common - short-chain dehydrogenase/reductase SDR Pmen_0069 230 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 146306503 Common - protease Do Pmen_1471 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 146305370 Common - binding-protein-dependent transport systems inner membrane component Pmen_0330 156 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 146308462 Common - protein of unknown function DUF1330 Pmen_3445 47 COG5470 COG5470, Uncharacterized conserved protein Function unknown 146307707 Common - Abortive infection protein Pmen_2685 15 COG4449 COG4449, Predicted protease of the Abi (CAAX) family General function prediction only 146307475 Common - Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family-like protein Pmen_2452 80 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 146306882 Common - histidinol-phosphate aminotransferase Pmen_1851 230 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 146308044 Common pcm protein-L-isoaspartate O-methyltransferase Pmen_3023 157 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 146306577 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Pmen_1546 148 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 146306981 Common - helix-turn-helix- domain containing protein, AraC type Pmen_1953 67 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 146308183 Common - protein of unknown function DUF861, cupin_3 Pmen_3163 33 COG3450 COG3450, Predicted enzyme of the cupin superfamily General function prediction only 146308469 Common - putative PAS/PAC sensor protein Pmen_3452 24 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 146305614 Common - (Glutamate--ammonia-ligase) adenylyltransferase Pmen_0577 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 146309609 Common - regulatory protein, IclR Pmen_4595 117 COG1414 IclR, Transcriptional regulator Transcription 146308386 Common - protein of unknown function DUF1704 Pmen_3367 16 COG3930 COG3930, Uncharacterized protein conserved in bacteria Function unknown 146305688 Common - hypothetical protein Pmen_0653 13 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 146309299 Common - polysaccharide export protein Pmen_4285 88 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 146308959 Common trpD anthranilate phosphoribosyltransferase Pmen_3945 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 146306293 Common - histidine triad (HIT) protein Pmen_1261 66 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 146305655 Common - hypothetical protein Pmen_0620 12 None None None 146308115 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Pmen_3094 80 COG0348 NapH, Polyferredoxin Energy production and conversion 146306777 Common - NLP/P60 protein Pmen_1746 136 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 146305099 Common - SUA5/yciO/yrdC, N-terminal domain Pmen_0058 236 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 146307370 Common - aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding Pmen_2345 117 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 146307994 Common - helix-turn-helix- domain containing protein, AraC type Pmen_2972 85 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 146306768 Common - hypothetical protein Pmen_1737 30 COG3122 COG3122, Uncharacterized protein conserved in bacteria Function unknown 146309436 Common fliP flagellar biosynthesis protein FliP Pmen_4422 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 146309613 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Pmen_4599 199 COG0388 COG0388, Predicted amidohydrolase General function prediction only 146308558 Common - Ribosomal protein L11 methylase-like protein Pmen_3543 88 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 146306232 Common - ATP-dependent protease-like protein Pmen_1200 127 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 146307866 Common flgH flagellar basal body L-ring protein Pmen_2844 99 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 146307010 Common ihfA integration host factor subunit alpha Pmen_1982 209 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 146308859 Common - TonB-dependent receptor, plug Pmen_3845 131 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 146307190 Common - protein of unknown function DUF1272 Pmen_2163 24 COG3813 COG3813, Uncharacterized protein conserved in bacteria Function unknown 146306282 Common - sodium/proline symporter Pmen_1250 160 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 146308360 Common - hypothetical protein Pmen_3341 2 None None None 146305291 Common - Acetyl-CoA hydrolase-like protein Pmen_0250 52 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 146307678 Common - multicopper oxidase, type 3 Pmen_2656 130 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 146308009 Common - hypothetical protein Pmen_2987 2 None None None 146309365 Common - hypothetical protein Pmen_4351 1 None None None 146309501 Common - protein of unknown function DUF796 Pmen_4487 31 COG3157 Hcp, Hemolysin-coregulated protein (uncharacterized) Function unknown 146308888 Common - NAD-dependent epimerase/dehydratase Pmen_3874 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 146306258 Common - hypothetical protein Pmen_1226 21 None None None 146306251 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Pmen_1219 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 146307583 Common - protein of unknown function DUF214 Pmen_2560 86 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 146307590 Common - TRAP dicarboxylate transporter, DctP subunit Pmen_2567 99 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 146309633 Common - putative inner membrane protein translocase component YidC Pmen_4620 204 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 146309072 Common - alpha/beta hydrolase-like protein Pmen_4058 28 COG4757 COG4757, Predicted alpha/beta hydrolase General function prediction only 146308371 Common - transcriptional regulator, TetR family Pmen_3352 107 COG1309 AcrR, Transcriptional regulator Transcription 146305176 Common - amino acid carrier protein Pmen_0135 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 146305254 Common flgI flagellar basal body P-ring protein Pmen_0213 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 146307874 Common - putative CheW protein Pmen_2852 187 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 146308273 Common - hypothetical protein Pmen_3253 1 None None None 146306458 Common - integral membrane protein-like protein Pmen_1426 20 COG5615 COG5615, Predicted integral membrane protein Function unknown 146309237 Common - ribose-5-phosphate isomerase A Pmen_4223 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 146306673 Common - protein of unknown function DUF1285 Pmen_1642 45 COG3816 COG3816, Uncharacterized protein conserved in bacteria Function unknown 146308623 Common infB translation initiation factor IF-2 Pmen_3608 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 146307116 Common - Mg2+ transporter protein, CorA family protein Pmen_2088 40 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 146308108 Common - Gentamicin 3'-N-acetyltransferase Pmen_3087 8 COG0456 RimI, Acetyltransferases General function prediction only 146306596 Common - Protein-glutamate O-methyltransferase Pmen_1565 128 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 146308502 Common - hypothetical protein Pmen_3487 2 None None None 146307972 Common - hypothetical protein Pmen_2950 23 None None None 146309210 Common - phospholipid/glycerol acyltransferase Pmen_4196 37 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 146307333 Pathogen - hypothetical protein Pmen_2308 1 COG3729 GsiB, General stress protein General function prediction only 146305420 Common - acyl-CoA dehydrogenase domain protein Pmen_0380 147 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 146306014 Common - hypothetical protein Pmen_0979 7 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 146305334 Pathogen - hypothetical protein Pmen_0293 1 None None None 146307305 Common - malto-oligosyltrehalose synthase Pmen_2280 116 COG3280 TreY, Maltooligosyl trehalose synthase Carbohydrate transport and metabolism 146308000 Common - major facilitator superfamily MFS_1 Pmen_2978 61 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 146307037 Common - cystine transporter subunit Pmen_2009 174 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146308427 Common - Carbonic anhydrase/acetyltransferase isoleucine patch superfamily-like protein Pmen_3408 200 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 146308444 Common - hypothetical protein Pmen_3425 29 None None None 146308809 Common - Serine-type D-Ala-D-Ala carboxypeptidase Pmen_3794 156 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 146306213 Common - DNA repair protein RadC Pmen_1181 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 146309408 Common - transcriptional regulator, AraC family Pmen_4394 122 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 146307295 Pathogen - hypothetical protein Pmen_2270 1 None None None 146305147 Common - protein kinase Pmen_0106 142 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 146308832 Common - acyl-CoA synthetase Pmen_3817 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 146306358 Common - transcriptional regulator, LysR family Pmen_1326 187 COG0583 LysR, Transcriptional regulator Transcription 146307651 Common - hypothetical protein Pmen_2628 12 None None None 146307364 Common - UDP-glucose 4-epimerase Pmen_2339 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 146308208 Common - hypothetical protein Pmen_3188 1 None None None 146307385 Common - short chain dehydrogenase Pmen_2360 138 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 146307558 Common - hypothetical protein Pmen_2535 19 None None None 146306071 Common - molybdopterin biosynthesis MoaE protein Pmen_1036 158 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 146307538 Common - lipid A ABC exporter family, fused ATPase and inner membrane subunits Pmen_2515 247 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 146308881 Common - hypothetical protein Pmen_3867 15 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 146307614 Common - acetyl-CoA acetyltransferase Pmen_2591 184 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 146305637 Common - aspartyl protease-like protein Pmen_0602 52 COG3577 COG3577, Predicted aspartyl protease General function prediction only 146307314 Common - hypothetical protein Pmen_2289 1 None None None 146306633 Common - protein of unknown function DUF539 Pmen_1602 7 COG2991 COG2991, Uncharacterized protein conserved in bacteria Function unknown 146307911 Common - phosphonate ABC transporter, periplasmic phosphonate-binding protein Pmen_2889 88 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 146306421 Common - hypothetical protein Pmen_1389 1 None None None 146305644 Common - thiamine biosynthesis protein ThiC Pmen_0609 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 146308477 Common - glycine cleavage T protein (aminomethyl transferase) Pmen_3460 180 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 146308709 Common - methylmalonate-semialdehyde dehydrogenase Pmen_3694 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 146305523 Common - binding-protein-dependent transport systems inner membrane component Pmen_0486 182 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 146307963 Common - protein of unknown function DUF1315 Pmen_2941 27 COG3139 COG3139, Uncharacterized protein conserved in bacteria Function unknown 146305750 Common - 3-dehydroquinate dehydratase Pmen_0715 169 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 146308418 Common trmD tRNA (guanine-N(1)-)-methyltransferase Pmen_3399 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 146307356 Common - ATPase AAA-2 domain protein Pmen_2331 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 146307118 Common - Conserved TM helix repeat-containing protein Pmen_2090 8 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 146306280 Common - phosphate-selective porin O and P Pmen_1248 23 COG3746 OprP, Phosphate-selective porin Inorganic ion transport and metabolism 146309320 Common - outer membrane porin Pmen_4306 10 None None None 146307588 Common - lipase chaperone Pmen_2565 18 COG5380 LimK, Lipase chaperone Posttranslational modification, protein turnover, chaperones 146307257 Common - blue (type 1) copper domain protein Pmen_2231 27 COG4454 COG4454, Uncharacterized copper-binding protein Inorganic ion transport and metabolism 146308606 Common - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase Pmen_3591 202 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 146307297 Common - hypothetical protein Pmen_2272 22 None None None 146308446 Pathogen - hypothetical protein Pmen_3427 1 None None None 162286124 Common - bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase Pmen_2578 223 COG1049 AcnB, Aconitase B Energy production and conversion 146309185 Pathogen - hypothetical protein Pmen_4171 1 None None None 146305201 Common - transposase IS66 Pmen_0160 67 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 146307490 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase Pmen_2467 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 146307940 Common - general secretion pathway protein L Pmen_2918 12 COG3297 PulL, Type II secretory pathway, component PulL Intracellular trafficking and secretion 146309598 Common - Mg-chelatase subunit ChlD-like protein Pmen_4584 46 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 146309164 Common - alanine racemase domain protein Pmen_4150 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 146306041 Common - acetolactate synthase 3 catalytic subunit Pmen_1006 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 146309182 Common - thiamine biosynthesis protein ThiS Pmen_4168 80 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 146308055 Common - 2-dehydro-3-deoxyphosphooctonate aldolase Pmen_3034 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 146307242 Common - protein of unknown function DUF411 Pmen_2215 64 COG3019 COG3019, Predicted metal-binding protein General function prediction only 146308404 Common - Rhomboid family protein Pmen_3385 20 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 146305806 Common - zinc-binding protein Pmen_0771 60 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 146309588 Common - precorrin-3B C17-methyltransferase Pmen_4574 125 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 146309636 Common - ribosomal protein L34 Pmen_4623 196 None None None 146305766 Common - protein of unknown function DUF1568 Pmen_0731 45 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 146305881 Common - protein of unknown function DUF541 Pmen_0846 23 COG3471 COG3471, Predicted periplasmic/secreted protein Function unknown 146309553 Common - Phosphoribosyl-AMP cyclohydrolase Pmen_4539 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 146305918 Common hisG ATP phosphoribosyltransferase catalytic subunit Pmen_0883 209 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 146307150 Common - hypothetical protein Pmen_2123 3 None None None 146308227 Pathogen - hypothetical protein Pmen_3207 1 None None None 146309270 Common hisB imidazoleglycerol-phosphate dehydratase Pmen_4256 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 146305703 Common - ferredoxin Pmen_0668 58 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 146307933 Common argD bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein Pmen_2911 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 146309617 Common - Lysine exporter protein (LYSE/YGGA) Pmen_4604 107 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 146308417 Common rplS 50S ribosomal protein L19 Pmen_3398 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 146307412 Common - thioredoxin reductase Pmen_2389 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 146307226 Common - aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding Pmen_2199 111 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 146305247 Common - flagellar basal-body rod protein FlgB Pmen_0206 64 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 146308490 Common - Sarcosine oxidase, delta subunit, heterotetrameric Pmen_3473 27 COG4311 SoxD, Sarcosine oxidase delta subunit Amino acid transport and metabolism 146309319 Common - hypothetical protein Pmen_4305 2 None None None 146306610 Common - hypothetical protein Pmen_1579 4 None None None 146309115 Common - Na+/solute symporter Pmen_4101 147 COG4147 DhlC, Predicted symporter General function prediction only 146306531 Common - transcriptional regulator, MarR family Pmen_1499 95 COG1846 MarR, Transcriptional regulators Transcription 146305194 Common - hypothetical protein Pmen_0153 14 None None None 146308267 Common - Pyruvate dehydrogenase (acetyl-transferring) Pmen_3247 158 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 146307157 Common - Elongation factor, KOW domain protein Pmen_2130 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 146305200 Common - Endonuclease/exonuclease/phosphatase Pmen_0159 37 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 146307687 Common - protein of unknown function DUF894, DitE Pmen_2665 116 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 146307249 Common - hypothetical protein Pmen_2222 62 COG3220 COG3220, Uncharacterized protein conserved in bacteria Function unknown 146306989 Common - beta-lactamase domain protein Pmen_1961 36 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 146307856 Common - flagellar protein FlaG protein Pmen_2834 31 COG1334 FlaG, Uncharacterized flagellar protein FlaG Cell motility and secretion 146306406 Common - enoyl-CoA hydratase Pmen_1374 186 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 146307647 Common - DSBA oxidoreductase Pmen_2624 47 COG3917 NahD, 2-hydroxychromene-2-carboxylate isomerase Secondary metabolites biosynthesis, transport, and catabolism 146305352 Common - CDP-6-deoxy-delta-3,4-glucoseen reductase Pmen_0311 97 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 146306211 Common - hypothetical protein Pmen_1179 4 None None None 146305209 Common - response regulator receiver protein Pmen_0168 215 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 146308123 Common - hypothetical protein Pmen_3102 27 None None None 146309260 Common - phosphoglyceromutase Pmen_4246 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 146306538 Pathogen - hypothetical protein Pmen_1506 1 None None None 146306991 Common - Pyrrolo-quinoline quinone Pmen_1963 89 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 146308692 Common - malate:quinone oxidoreductase Pmen_3677 54 COG0579 COG0579, Predicted dehydrogenase General function prediction only 146308846 Common - Gamma-glutamyltransferase Pmen_3832 146 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 146305608 Pathogen - hypothetical protein Pmen_0571 1 None None None 146305736 Common - ABC-type branched-chain amino acid transport systems periplasmic component-like protein Pmen_0701 105 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 146305905 Common - RNA polymerase factor sigma-54 Pmen_0870 145 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 146308642 Common - ferric uptake regulator, Fur family Pmen_3627 188 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 146307319 Common - trehalose synthase Pmen_2294 169 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 146306104 Common - protein of unknown function DUF1486 Pmen_1070 28 None None None 146307393 Common - potassium efflux system protein Pmen_2368 202 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 146306639 Common - lipoprotein releasing system, ATP-binding protein Pmen_1608 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 146309158 Common - nitrogen metabolism transcriptional regulator, NtrC, Fis Family Pmen_4144 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 146305080 Common - type III secretion protein, HrcV family Pmen_0039 127 COG4789 EscV, Type III secretory pathway, component EscV Intracellular trafficking and secretion 146307815 Common - cytoplasmic domain of flagellar protein FhlB-like protein Pmen_2793 13 COG2257 COG2257, Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB Function unknown 146306860 Common - integral membrane sensor signal transduction histidine kinase Pmen_1829 61 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146307325 Common - Alcohol dehydrogenase GroES domain protein Pmen_2300 206 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 146305964 Common - hypothetical protein Pmen_0929 2 COG4701 COG4701, Uncharacterized protein conserved in bacteria Function unknown 146309033 Common - hypothetical protein Pmen_4019 71 COG2719 SpoVR, Uncharacterized conserved protein Function unknown 146306600 Pathogen - hypothetical protein Pmen_1569 1 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 146309236 Common - hypothetical protein Pmen_4222 13 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 146308712 Common - Nucleoside-binding outer membrane protein-like protein Pmen_3697 20 COG3248 Tsx, Nucleoside-binding outer membrane protein Cell envelope biogenesis, outer membrane 146306064 Common - type IV pilus assembly PilZ Pmen_1029 2 None None None 146307785 Common - Nucleoside-binding outer membrane protein-like protein Pmen_2763 16 COG3248 Tsx, Nucleoside-binding outer membrane protein Cell envelope biogenesis, outer membrane 146305481 Common - Alkane 1-monooxygenase Pmen_0443 26 None None None 146307391 Common - binding-protein-dependent transport systems inner membrane component Pmen_2366 178 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 146307655 Common - Alpha/beta hydrolase fold-3 domain protein Pmen_2632 137 COG0657 Aes, Esterase/lipase Lipid metabolism 146308682 Common - protein of unknown function DUF1486 Pmen_3667 1 COG5485 COG5485, Predicted ester cyclase General function prediction only 146308164 Common - DNA-binding transcriptional regulator HexR Pmen_3144 101 COG1737 RpiR, Transcriptional regulators Transcription 146309022 Common - Nucleotidyl transferase Pmen_4008 220 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 146307168 Common - Bile acid:sodium symporter Pmen_2141 65 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 146307419 Common - isocitrate dehydrogenase, NADP-dependent Pmen_2396 222 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 146306036 Common - hypothetical protein Pmen_1001 58 COG2187 COG2187, Uncharacterized protein conserved in bacteria Function unknown 146309088 Common - protein of unknown function DUF886 Pmen_4074 38 COG3758 COG3758, Uncharacterized protein conserved in bacteria Function unknown 146308339 Common - hypothetical protein Pmen_3319 4 None None None 146305236 Common - transcriptional regulator, CadC Pmen_0195 19 COG3710 CadC, DNA-binding winged-HTH domains Transcription 146308715 Common - protein of unknown function UPF0029 Pmen_3700 131 COG1739 COG1739, Uncharacterized conserved protein Function unknown 146309375 Common - TRAP dicarboxylate transporter- DctP subunit Pmen_4361 85 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 146305908 Common - protein of unknown function DUF1239 Pmen_0873 20 COG3117 COG3117, Uncharacterized protein conserved in bacteria Function unknown 146305870 Common - multi-sensor hybrid histidine kinase Pmen_0835 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146308773 Common - CRISPR-associated protein, Cse4 family Pmen_3758 42 None None None 146305384 Common - extracellular solute-binding protein, family 1 Pmen_0344 131 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 146305465 Common - recA protein Pmen_0425 237 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 146308667 Common - helix-turn-helix- domain containing protein, AraC type Pmen_3652 75 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 146306767 Common mazG nucleoside triphosphate pyrophosphohydrolase Pmen_1736 158 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 146305314 Common cyaA adenylate cyclase Pmen_0273 25 COG3072 CyaA, Adenylate cyclase Nucleotide transport and metabolism 146309419 Common - hypothetical protein Pmen_4405 1 None None None 146308724 Common - TonB-dependent receptor Pmen_3709 110 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 146307996 Common - methyl-accepting chemotaxis sensory transducer Pmen_2974 141 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146306974 Common - ABC transporter related Pmen_1946 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 146307847 Common fliF flagellar MS-ring protein Pmen_2825 125 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 146308972 Pathogen - hypothetical protein Pmen_3958 1 None None None 146305460 Common - DEAD/DEAH box helicase domain protein Pmen_0420 238 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 146309132 Pathogen - hypothetical protein Pmen_4118 1 COG3755 COG3755, Uncharacterized protein conserved in bacteria Function unknown 146308020 Common - hypothetical protein Pmen_2998 19 None None None 146305067 Pathogen - hypothetical protein Pmen_0025 1 None None None 146306119 Common - putative transcriptional regulator, GntR family Pmen_1085 183 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 146309453 Common - glutathione-dependent formaldehyde-activating, GFA Pmen_4439 65 COG3791 COG3791, Uncharacterized conserved protein Function unknown 146306889 Common - oxidoreductase domain protein Pmen_1858 68 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 146305396 Common - glutamate--cysteine ligase Pmen_0356 58 COG2918 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 146309594 Common - major facilitator superfamily MFS_1 Pmen_4580 144 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 146305603 Common - Appr-1-p processing domain protein Pmen_0566 30 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 146306709 Common - GDP-mannose 6-dehydrogenase Pmen_1678 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 146308204 Common - GCN5-related N-acetyltransferase Pmen_3184 1 None None None 146307208 Common - efflux transporter, RND family, MFP subunit Pmen_2181 130 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 146306867 Common - hypothetical protein Pmen_1836 7 None None None 146308434 Common - Lytic transglycosylase, catalytic Pmen_3415 145 COG4623 COG4623, Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein Cell envelope biogenesis, outer membrane 146306491 Common - two component transcriptional regulator, winged helix family Pmen_1459 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 146307677 Common - blue (type 1) copper domain protein Pmen_2655 29 COG4454 COG4454, Uncharacterized copper-binding protein Inorganic ion transport and metabolism 146306561 Common - major facilitator superfamily MFS_1 Pmen_1530 17 COG3202 COG3202, ATP/ADP translocase Energy production and conversion 146306980 Common - PEBP family protein Pmen_1952 118 COG1881 COG1881, Phospholipid-binding protein General function prediction only 146308656 Common - Peroxiredoxin Pmen_3641 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 146307834 Common fliP flagellar biosynthesis protein FliP Pmen_2812 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 146307543 Common - hypothetical protein Pmen_2520 1 None None None 146308156 Common - Glucan 1,4-alpha-maltotetraohydrolase Pmen_3136 28 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 146305369 Pathogen - hypothetical protein Pmen_0328 1 None None None 146307714 Common - acyl-CoA dehydrogenase domain protein Pmen_2692 162 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 146308243 Common - Oxidoreductase FAD-binding domain protein Pmen_3223 148 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 146308755 Common - hypothetical protein Pmen_3740 4 None None None 146306112 Common - major facilitator superfamily MFS_1 Pmen_1078 183 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 146308257 Common - glycoside hydrolase, family 3 domain protein Pmen_3237 143 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 146308814 Common - hypothetical protein Pmen_3799 167 COG1576 COG1576, Uncharacterized conserved protein Function unknown 146309353 Common - molybdenum ABC transporter, periplasmic molybdate-binding protein Pmen_4339 138 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 146307944 Common - general secretion pathway protein H Pmen_2922 4 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 146305715 Pathogen - hypothetical protein Pmen_0680 2 None None None 146306422 Common - BFD domain protein (2Fe-2S)-binding domain protein Pmen_1390 36 COG2906 Bfd, Bacterioferritin-associated ferredoxin Inorganic ion transport and metabolism 146305954 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase Pmen_0919 227 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 146306681 Common - helix-turn-helix- domain containing protein, AraC type Pmen_1650 68 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 146309277 Common - Ribonuclease H Pmen_4263 161 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 146306125 Common - Succinylglutamate desuccinylase/aspartoacylase Pmen_1091 24 COG3608 COG3608, Predicted deacylase General function prediction only 146306691 Common - protein of unknown function UPF0118 Pmen_1660 137 COG0628 PerM, Predicted permease General function prediction only 146309398 Common - exodeoxyribonuclease III Xth Pmen_4384 195 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 146305448 Common - CheA signal transduction histidine kinase Pmen_0408 223 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 146309315 Common - type II secretion system protein E Pmen_4301 181 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 146306233 Common - hypothetical protein Pmen_1201 1 None None None 146308358 Common - glutaredoxin-like protein Pmen_3339 126 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 146305158 Common - ABC-type amino acid transport/signal transduction systems periplasmic component/domain-like protein Pmen_0117 14 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146305686 Common - periplasmic/7TM domain sensor diguanylate cyclase Pmen_0651 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 146307953 Common - hypothetical protein Pmen_2931 1 None None None 146306569 Pathogen - hypothetical protein Pmen_1538 2 None None None 146307023 Common - two component transcriptional regulator, winged helix family Pmen_1995 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 146306081 Common - hypothetical protein Pmen_1046 26 COG4691 StbC, Plasmid stability protein General function prediction only 146308997 Common - putative phage repressor Pmen_3983 39 COG2932 COG2932, Predicted transcriptional regulator Transcription 146305044 Common - DNA polymerase III subunit beta Pmen_0002 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 146306020 Common - hypothetical protein Pmen_0985 2 None None None 146306146 Common - hypothetical protein Pmen_1112 1 None None None 146306333 Common - carboxylate/amino acid/amine transporter Pmen_1301 23 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 146307032 Pathogen - hypothetical protein Pmen_2004 1 None None None 146309422 Common - two component transcriptional regulator, winged helix family Pmen_4408 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 146309345 Common - aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein Pmen_4331 101 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 146305325 Common - Disulphide bond formation protein DsbB Pmen_0284 50 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 146306001 Common - integral membrane sensor signal transduction histidine kinase Pmen_0966 222 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 146307665 Common - GCN5-related N-acetyltransferase Pmen_2643 95 COG0456 RimI, Acetyltransferases General function prediction only 146308406 Common - hypothetical protein Pmen_3387 51 COG2268 COG2268, Uncharacterized protein conserved in bacteria Function unknown 146308788 Common thiE thiamine-phosphate pyrophosphorylase Pmen_3773 146 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 146309304 Common - glucose-1-phosphate thymidylyltransferase Pmen_4290 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 146308499 Common - phage integrase family protein Pmen_3484 106 COG0582 XerC, Integrase DNA replication, recombination, and repair 146305300 Common - nitrogen regulatory protein P-II Pmen_0259 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 146306655 Common - protein of unknown function DUF177 Pmen_1624 26 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 146309461 Common - helix-turn-helix- domain containing protein, AraC type Pmen_4447 78 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 146309566 Common - choline/carnitine/betaine transporter Pmen_4552 95 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 146309597 Common - precorrin 6A synthase Pmen_4583 35 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 146307070 Common - ABC transporter related Pmen_2042 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 146308928 Common rpsL 30S ribosomal protein S12 Pmen_3914 239 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 146307916 Pathogen - sodium pump decarboxylase, gamma subunit Pmen_2894 1 COG3630 OadG, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, gamma subunit Energy production and conversion 146305936 Common rplM 50S ribosomal protein L13 Pmen_0901 228 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 146308175 Common - aldo/keto reductase Pmen_3155 204 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 146305636 Common - DNA topoisomerase IV subunit A Pmen_0601 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 146305276 Common - major facilitator superfamily MFS_1 Pmen_0235 8 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 146306915 Common - hypothetical protein Pmen_1885 1 None None None 146309333 Common - TOBE domain protein Pmen_4319 43 COG3585 MopI, Molybdopterin-binding protein Coenzyme metabolism 146307941 Common - General secretion pathway protein K Pmen_2919 32 COG3156 PulK, Type II secretory pathway, component PulK Intracellular trafficking and secretion 146307406 Common - uroporphyrin-III C-methyltransferase Pmen_2383 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 146305414 Common - flavoprotein involved in K+ transport-like protein Pmen_0374 63 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 146309410 Common - transcriptional regulator, LysR family Pmen_4396 190 COG0583 LysR, Transcriptional regulator Transcription 146309413 Pathogen - hypothetical protein Pmen_4399 1 None None None 146306733 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pmen_1702 23 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 146308637 Common - dihydrodipicolinate reductase Pmen_3622 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 146309005 Common - hypothetical protein Pmen_3991 33 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 146307805 Common - Tetratricopeptide TPR_2 repeat protein Pmen_2783 69 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 146305423 Common - hypothetical protein Pmen_0383 3 COG4872 COG4872, Predicted membrane protein Function unknown 146307706 Common - hypothetical protein Pmen_2684 2 None None None 146305357 Common - ABC transporter related Pmen_0316 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 146305514 Common - extracellular solute-binding protein, family 3 Pmen_0477 27 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146306436 Common - electron transport complex, RnfABCDGE type, A subunit Pmen_1404 76 COG4657 RnfA, Predicted NADH:ubiquinone oxidoreductase, subunit RnfA Energy production and conversion 146308934 Common rplK 50S ribosomal protein L11 Pmen_3920 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 146306801 Common - phospholipid/glycerol acyltransferase Pmen_1770 107 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 146309468 Common - hypothetical protein Pmen_4454 1 None None None 146308429 Common - NUDIX hydrolase Pmen_3410 118 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 146307886 Common - MbtH domain protein Pmen_2864 34 COG3251 COG3251, Uncharacterized protein conserved in bacteria Function unknown 146305223 Common - phosphate ABC transporter, ATPase subunit Pmen_0182 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 146308831 Common - PAS/PAC sensor signal transduction histidine kinase Pmen_3816 205 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 146307365 Common - glycosyl transferase, group 1 Pmen_2340 46 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 146306218 Common - hypothetical protein Pmen_1186 4 None None None 146309524 Common - TonB-dependent hemoglobin/transferrin/lactoferrin family receptor Pmen_4510 126 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 146306872 Common - RNA-binding S4 domain protein Pmen_1841 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 146307445 Common - NADH dehydrogenase subunit L Pmen_2422 207 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 146309128 Common - transposase IS66 Pmen_4114 67 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 146308410 Common - L-carnitine dehydratase/bile acid-inducible protein F Pmen_3391 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 146305537 Common - protein of unknown function DUF849 Pmen_0500 62 COG3246 COG3246, Uncharacterized conserved protein Function unknown 146306223 Common - RNA 3'-terminal-phosphate cyclase Pmen_1191 47 COG0430 RCL1, RNA 3'-terminal phosphate cyclase RNA processing and modification 146306826 Common - hypothetical protein Pmen_1795 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 146306903 Common - UDP-N-acetylglucosamine 2-epimerase Pmen_1873 153 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 146308536 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase Pmen_3521 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 146307047 Common - NADH dehydrogenase subunit L Pmen_2019 196 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 146307422 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase Pmen_2399 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 146309070 Common - NADPH-dependent FMN reductase Pmen_4056 106 COG0431 COG0431, Predicted flavoprotein General function prediction only 146308990 Common - phage holin, lambda family Pmen_3976 1 None None None 146309432 Common - flagellar hook-basal body complex subunit FliE Pmen_4418 20 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 146309298 Common - lipopolysaccharide biosynthesis protein Pmen_4284 28 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 146306008 Pathogen - hypothetical protein Pmen_0973 1 None None None 146307081 Common - histone family protein DNA-binding protein Pmen_2053 208 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 146305889 Common gatA aspartyl/glutamyl-tRNA amidotransferase subunit A Pmen_0854 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 146309515 Common - isochorismatase hydrolase Pmen_4501 129 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 146307430 Common - isocitrate lyase Pmen_2407 114 COG2224 AceA, Isocitrate lyase Energy production and conversion 146306816 Common - hypothetical protein Pmen_1785 6 None None None 146306622 Common - 5'-methylthioadenosine phosphorylase Pmen_1591 162 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 146305993 Common - Tfp pilus assembly protein tip-associated adhesin PilY1-like protein Pmen_0958 38 COG3419 PilY1, Tfp pilus assembly protein, tip-associated adhesin PilY1 Cell motility and secretion / Intracellular trafficking and secretion 146307367 Common - hypothetical protein Pmen_2342 10 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 146306166 Common - phospholipase D/Transphosphatidylase Pmen_1132 151 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 146306523 Pathogen - protein of unknown function DUF1656 Pmen_1491 1 None None None 146308527 Common - transcriptional regulator, BadM/Rrf2 family Pmen_3512 172 COG1959 COG1959, Predicted transcriptional regulator Transcription 146305390 Common - adenylate cyclase Pmen_0350 47 COG3025 COG3025, Uncharacterized conserved protein Function unknown 146305923 Common - 2-alkenal reductase Pmen_0888 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 146309549 Common - hypothetical protein Pmen_4535 16 None None None 146305512 Common - Citrate transporter Pmen_0475 120 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 146308921 Common rplW 50S ribosomal protein L23 Pmen_3907 216 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 146306571 Common - Tetratricopeptide TPR_2 repeat protein Pmen_1540 10 COG4700 COG4700, Uncharacterized protein conserved in bacteria containing a divergent form of TPR repeats Function unknown 146307896 Common - sodium:neurotransmitter symporter Pmen_2874 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 146305548 Common - Lipocalin family protein Pmen_0511 73 COG3040 Blc, Bacterial lipocalin Cell envelope biogenesis, outer membrane 146308078 Common - hypothetical protein Pmen_3057 7 None None None 146307570 Common - UspA domain protein Pmen_2547 38 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 146305542 Common - membrane protein-like protein Pmen_0505 22 COG5373 COG5373, Predicted membrane protein Function unknown 146305941 Common - Glutathione S-transferase, N-terminal domain Pmen_0906 74 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 146309572 Common - hypothetical protein Pmen_4558 11 COG4729 COG4729, Uncharacterized conserved protein Function unknown 146309366 Common - protein of unknown function DUF962 Pmen_4352 25 COG4539 COG4539, Predicted membrane protein Function unknown 146306315 Common - conserved hypothetical protein 730 Pmen_1283 101 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 146307526 Common kgd alpha-ketoglutarate decarboxylase Pmen_2503 147 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 146308706 Common - hypothetical protein Pmen_3691 72 COG1432 COG1432, Uncharacterized conserved protein Function unknown 146308954 Common - protein of unknown function DUF323 Pmen_3940 112 COG1262 COG1262, Uncharacterized conserved protein Function unknown 146309495 Common - protein of unknown function DUF182 Pmen_4481 112 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 146308591 Common - peptidylprolyl isomerase, FKBP-type Pmen_3576 150 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 146306998 Common - peptidase S9, prolyl oligopeptidase active site domain protein Pmen_1970 108 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 146305260 Common - hypothetical protein Pmen_0219 15 None None None 146309429 Common fliH flagellar assembly protein H Pmen_4415 37 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 146307770 Common - chromosome segregation protein SMC Pmen_2748 179 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 146307181 Common - methyl-accepting chemotaxis sensory transducer Pmen_2154 139 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146309407 Common - Lysine exporter protein (LYSE/YGGA) Pmen_4393 59 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 146306429 Common - hypothetical protein Pmen_1397 1 None None None 146308086 Common - iron-containing alcohol dehydrogenase Pmen_3065 132 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 146308237 Common ligD ATP-dependent DNA ligase Pmen_3217 113 COG3285 COG3285, Predicted eukaryotic-type DNA primase DNA replication, recombination, and repair 146306794 Common - acetyltransferase and hydrolase with the alpha/beta hydrolase fold-like protein Pmen_1763 21 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 146306800 Common - Rhodanese domain protein Pmen_1769 139 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 146306248 Common - Glucarate dehydratase Pmen_1216 57 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 146305564 Common - transcriptional regulator, TetR family Pmen_0527 61 COG1309 AcrR, Transcriptional regulator Transcription 146308603 Common - multi-sensor signal transduction histidine kinase Pmen_3588 226 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 146306743 Common - hypothetical protein Pmen_1712 6 None None None 146306616 Common - hypothetical protein Pmen_1585 5 None None None 146305096 Common def peptide deformylase Pmen_0055 213 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 146306701 Common - hypothetical protein Pmen_1670 3 None None None 146309231 Common - PTSINtr with GAF domain, PtsP Pmen_4217 235 COG3605 PtsP, Signal transduction protein containing GAF and PtsI domains Signal transduction mechanisms 146308727 Common - Alcohol dehydrogenase, zinc-binding domain protein Pmen_3712 174 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 146306363 Common - Uncharacterized protein of the AP superfamily-like protein Pmen_1331 20 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 146305339 Common - Uncharacterized membrane-associated protein-like protein Pmen_0298 47 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 146308604 Common - putative two component, sigma54 specific, transcriptional regulator, Fis family Pmen_3589 220 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 146307274 Common - hypothetical protein Pmen_2248 28 COG4275 COG4275, Uncharacterized conserved protein Function unknown 146307423 Common - hypothetical protein Pmen_2400 41 COG2915 COG2915, Uncharacterized protein involved in purine metabolism General function prediction only 146307821 Common - flagellar motor protein MotD Pmen_2799 161 COG1360 MotB, Flagellar motor protein Cell motility and secretion 146305519 Common - betaine aldehyde dehydrogenase Pmen_0482 223 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 146306833 Common - type I secretion membrane fusion protein, HlyD family Pmen_1802 116 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 146305182 Common - hypothetical protein Pmen_0141 4 None None None 146306772 Common - glutaredoxin 2 Pmen_1741 13 None None None 146307740 Common - Tfp pilus assembly protein FimV-like protein Pmen_2718 38 COG3170 FimV, Tfp pilus assembly protein FimV Cell motility and secretion / Intracellular trafficking and secretion 146305456 Common - Citrate transporter Pmen_0416 45 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 146307974 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Pmen_2952 4 None None None 146309178 Common - hypothetical protein Pmen_4164 9 None None None 146308504 Common - transcriptional regulator, LysR family Pmen_3489 161 COG0583 LysR, Transcriptional regulator Transcription 146305675 Common hisZ ATP phosphoribosyltransferase regulatory subunit Pmen_0640 212 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 146309062 Common - Citrate transporter Pmen_4048 44 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 146306290 Common - prolyl-tRNA synthetase Pmen_1258 247 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 146307876 Common - anti-sigma-28 factor, FlgM Pmen_2854 21 COG2747 FlgM, Negative regulator of flagellin synthesis (anti-sigma28 factor) Transcription / Cell motility and secretion / Intracellular trafficking and secretion 146306096 Common - molybdopterin biosynthesis protein MoeB Pmen_1062 223 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 146305179 Common - Endoribonuclease L-PSP Pmen_0138 131 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 146308442 Common - hypothetical protein Pmen_3423 1 None None None 146305340 Common - delta-aminolevulinic acid dehydratase Pmen_0299 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 146306063 Common - Sel1 domain protein repeat-containing protein Pmen_1028 7 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 146307442 Common - NADH dehydrogenase subunit I Pmen_2419 190 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 146307119 Common - RNA polymerase sigma factor SigX Pmen_2091 164 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 146305070 Common - type III secretion apparatus lipoprotein, YscJ/HrcJ family Pmen_0028 73 COG4669 EscJ, Type III secretory pathway, lipoprotein EscJ Intracellular trafficking and secretion 146305862 Common - drug resistance transporter, Bcr/CflA subfamily Pmen_0827 192 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 146305757 Common - Hemolysin-type calcium-binding region Pmen_0722 85 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 146307606 Common - aminotransferase, class I and II Pmen_2583 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 146309383 Common - helix-turn-helix- domain containing protein, AraC type Pmen_4369 64 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 146305987 Common - bifunctional riboflavin kinase/FMN adenylyltransferase Pmen_0952 211 COG0196 RibF, FAD synthase Coenzyme metabolism 146305212 Common - CheB methylesterase Pmen_0171 142 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 146308002 Common - NapD family protein Pmen_2980 24 COG3062 NapD, Uncharacterized protein involved in formation of periplasmic nitrate reductase Inorganic ion transport and metabolism 146306342 Common mgsA methylglyoxal synthase Pmen_1310 83 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 146309155 Common - hypothetical protein Pmen_4141 15 None None None 146309206 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Pmen_4192 113 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 146306927 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pmen_1898 33 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 146307298 Common katE hydroperoxidase II Pmen_2273 125 COG0753 KatE, Catalase Inorganic ion transport and metabolism 146307586 Common - 2'-5' RNA ligase Pmen_2563 16 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 146308917 Common rpsC 30S ribosomal protein S3 Pmen_3903 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 146306861 Common - protein of unknown function, Spy-related Pmen_1830 1 COG3678 CpxP, P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein Intracellular trafficking and secretion / Cell motility and secretio / Signal transduction mechanisms / Inorganic ion transport and metabolism 146307496 Common - protein tyrosine/serine phosphatase Pmen_2473 12 COG2365 COG2365, Protein tyrosine/serine phosphatase Signal transduction mechanisms 146307034 Common - transcriptional regulator, LysR family Pmen_2006 180 COG0583 LysR, Transcriptional regulator Transcription 146309570 Common - TonB-dependent siderophore receptor Pmen_4556 103 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 146306671 Common - Radical SAM domain protein Pmen_1640 50 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 146305479 Common - Rubredoxin-type Fe(Cys)4 protein Pmen_0441 114 COG1773 COG1773, Rubredoxin Energy production and conversion 146305101 Common - coproporphyrinogen III oxidase Pmen_0060 113 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 146307377 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pmen_2352 10 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 146307616 Common - hypothetical protein Pmen_2593 12 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 146309212 Common - putative signal transduction protein Pmen_4198 61 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 146307285 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Pmen_2260 62 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 146307004 Common thrS threonyl-tRNA synthetase Pmen_1976 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 146307738 Common - N-(5'-phosphoribosyl)anthranilate isomerase Pmen_2716 194 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 146308374 Common - protein of unknown function DUF72 Pmen_3355 102 COG1801 COG1801, Uncharacterized conserved protein Function unknown 146309621 Common - F0F1 ATP synthase subunit gamma Pmen_4608 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 146307358 Common - hypothetical protein Pmen_2333 8 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 146305959 Common ddl D-alanine--D-alanine ligase Pmen_0924 217 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 146305551 Common - D-tyrosyl-tRNA deacylase Pmen_0514 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 146309008 Common - phage transcriptional regulator, AlpA Pmen_3994 21 COG3311 AlpA, Predicted transcriptional regulator Transcription 146306301 Common - hypothetical protein Pmen_1269 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 146306130 Pathogen - hypothetical protein Pmen_1096 1 None None None 146307110 Common - aconitate hydratase Pmen_2082 223 COG1048 AcnA, Aconitase A Energy production and conversion 146306591 Common - carbohydrate kinase, FGGY Pmen_1560 183 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 146306598 Common - methyl-accepting chemotaxis sensory transducer Pmen_1567 142 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146307536 Common - protein of unknown function DUF1255 Pmen_2513 51 COG3123 COG3123, Uncharacterized protein conserved in bacteria Function unknown 146305087 Common - type III secretion system protein Pmen_0046 128 COG4790 EscR, Type III secretory pathway, component EscR Intracellular trafficking and secretion 146306073 Common - metallophosphoesterase Pmen_1038 118 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 146306897 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Pmen_1867 62 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 146307559 Common - peptidase C39, bacteriocin processing Pmen_2536 30 COG3271 COG3271, Predicted double-glycine peptidase General function prediction only 146305251 Common - flagellar basal-body rod protein FlgF Pmen_0210 123 COG4787 FlgF, Flagellar basal body rod protein Cell motility and secretion 146305256 Common - flagellar hook-associated protein FlgK Pmen_0215 120 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 146307798 Common - RND efflux system, outer membrane lipoprotein, NodT family Pmen_2776 110 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 146307058 Common - Carbamoyl-phosphate synthase L chain, ATP-binding Pmen_2030 235 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 146305663 Common - oligoribonuclease Pmen_0628 88 COG1949 Orn, Oligoribonuclease (3'->5' exoribonuclease) RNA processing and modification 146308346 Common - Uncharacterized iron-regulated protein-like protein Pmen_3326 37 COG3487 IrpA, Uncharacterized iron-regulated protein Inorganic ion transport and metabolism 146305174 Common - GCN5-related N-acetyltransferase Pmen_0133 88 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 146309340 Common - GCN5-related N-acetyltransferase Pmen_4326 39 COG3153 COG3153, Predicted acetyltransferase General function prediction only 146307092 Common - Hydroxyacylglutathione hydrolase Pmen_2064 197 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 146307339 Common - protein phosphatase 2C domain protein Pmen_2314 135 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 146309140 Common - Alcohol dehydrogenase GroES domain protein Pmen_4126 190 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 146308050 Common - transcriptional regulator, LysR family Pmen_3029 176 COG0583 LysR, Transcriptional regulator Transcription 146306737 Common - hypothetical protein Pmen_1706 2 None None None 146305710 Common - TRAP dicarboxylate transporter- DctP subunit Pmen_0675 73 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 146305526 Pathogen - hypothetical protein Pmen_0489 1 None None None 146305613 Common aceE pyruvate dehydrogenase subunit E1 Pmen_0576 136 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 146308016 Common - protein of unknown function UPF0118 Pmen_2994 167 COG0628 PerM, Predicted permease General function prediction only 146307207 Common - transporter, hydrophobe/amphiphile efflux-1 (HAE1) family Pmen_2180 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 146307791 Common - glyoxylate carboligase Pmen_2769 221 COG3960 COG3960, Glyoxylate carboligase General function prediction only 146309486 Common - Fructuronate reductase Pmen_4472 90 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 146307531 Common gltA type II citrate synthase Pmen_2508 194 COG0372 GltA, Citrate synthase Energy production and conversion 146309502 Common - Rhs element Vgr protein Pmen_4488 59 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 146309078 Common - TonB-dependent receptor Pmen_4064 58 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 146305777 Common - MaoC domain protein dehydratase Pmen_0742 29 COG2030 MaoC, Acyl dehydratase Lipid metabolism 146308824 Common - LrgA family protein Pmen_3809 1 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 146309225 Common - hypothetical protein Pmen_4211 6 None None None 146309326 Common - multi-sensor signal transduction histidine kinase Pmen_4312 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 146308552 Common - isochorismatase hydrolase Pmen_3537 55 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 146305295 Common - diguanylate cyclase/phosphodiesterase Pmen_0254 169 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 146307233 Common - short-chain dehydrogenase/reductase SDR Pmen_2206 233 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 146307250 Common - hypothetical protein Pmen_2223 33 None None None 146306855 Common - membrane protein-like protein Pmen_1824 21 COG4323 COG4323, Predicted membrane protein Function unknown 146308796 Common - hypothetical protein Pmen_3781 173 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 146308872 Common - hypothetical protein Pmen_3858 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 146308829 Common - Methyltransferase type 11 Pmen_3814 127 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 146309547 Common - cobalamin synthesis protein, P47K Pmen_4533 122 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 146306235 Common - hypothetical protein Pmen_1203 1 None None None 146305471 Common - IS66 Orf2 family protein Pmen_0432 50 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 146307191 Common - transcriptional regulator, AraC family Pmen_2164 138 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 146309137 Common - protein of unknown function DUF785 Pmen_4123 34 COG4067 COG4067, Uncharacterized protein conserved in archaea Posttranslational modification, protein turnover, chaperones 146305618 Common - glycosyl transferase, group 1 Pmen_0581 154 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 146308556 Common - Alcohol dehydrogenase, zinc-binding domain protein Pmen_3541 189 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 146306285 Common - Membrane carboxypeptidase (penicillin-binding protein)-like protein Pmen_1253 16 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 146308625 Common - hypothetical protein Pmen_3610 178 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 146305401 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) Pmen_0361 192 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 146308618 Common - transport-associated Pmen_3603 42 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 146309097 Common - hypothetical protein Pmen_4083 3 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 146306693 Common - Glycine cleavage system regulatory protein-like protein Pmen_1662 28 COG2716 GcvR, Glycine cleavage system regulatory protein Amino acid transport and metabolism 146306720 Common - fumarate hydratase Pmen_1689 212 COG0114 FumC, Fumarase Energy production and conversion 146306489 Common - Uncharacterized protein UPF0065 Pmen_1457 69 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 146308091 Common - hypothetical protein Pmen_3070 5 None None None 146308467 Common - ABC transporter related Pmen_3450 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 146305164 Common - histone deacetylase superfamily Pmen_0123 160 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 146305846 Common - protein of unknown function RIO1 Pmen_0811 66 COG1718 RIO1, Serine/threonine protein kinase involved in cell cycle control Signal transduction mechanisms / Cell division and chromosome partitioning 146305496 Common - D-erythrose-4-phosphate dehydrogenase Pmen_0459 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 146307510 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Pmen_2487 142 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 146309538 Common - aminotransferase Pmen_4524 233 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 146306679 Common - hypothetical protein Pmen_1648 2 None None None 146305376 Pathogen - hypothetical protein Pmen_0336 1 None None None 146306254 Common - secreted protein-like protein Pmen_1222 16 COG5513 COG5513, Predicted secreted protein Function unknown 146305747 Common prmA ribosomal protein L11 methyltransferase Pmen_0712 174 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 146308361 Common - ornithine carbamoyltransferase Pmen_3342 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 146305112 Common - tryptophan synthase subunit beta Pmen_0071 225 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 146307752 Common - periplasmic/7TM domain sensor diguanylate cyclase Pmen_2730 179 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 146309280 Common - Resolvase, N-terminal domain Pmen_4266 83 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 146307960 Common - protein of unknown function DUF1302 Pmen_2938 18 None None None 146305650 Common - aldo/keto reductase Pmen_0615 173 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 146307548 Common - Thiopurine S-methyltransferase Pmen_2525 36 None None None 146308191 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Pmen_3171 148 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 146308505 Common xseA exodeoxyribonuclease VII large subunit Pmen_3490 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 146308891 Common - major facilitator superfamily MFS_1 Pmen_3877 218 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 146305059 Common - type IV pilus assembly PilZ Pmen_0017 5 None None None 146306710 Common - acriflavin resistance protein Pmen_1679 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 146305826 Common - Pyrrolo-quinoline quinone Pmen_0791 59 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 146308106 Common - IS66 Orf2 family protein Pmen_3085 50 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 146309582 Common - hypothetical protein Pmen_4568 37 COG3411 COG3411, Ferredoxin Energy production and conversion 146307304 Common - 4-alpha-glucanotransferase Pmen_2279 119 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 146306419 Common - Extracellular ligand-binding receptor Pmen_1387 149 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 146308904 Common rplO 50S ribosomal protein L15 Pmen_3890 204 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 146305634 Common - acyl-CoA dehydrogenase domain protein Pmen_0599 147 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 146308589 Common - TrkA-N domain protein Pmen_3574 87 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 146306544 Common - Lysophospholipase-like protein Pmen_1512 52 COG2267 PldB, Lysophospholipase Lipid metabolism 146309577 Common - Cyclopropane-fatty-acyl-phospholipid synthase Pmen_4563 131 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 146308241 Common - NADH:flavin oxidoreductase/NADH oxidase Pmen_3221 177 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 146305238 Common - Rubredoxin-type Fe(Cys)4 protein Pmen_0197 114 COG1773 COG1773, Rubredoxin Energy production and conversion 146307088 Common - extracellular solute-binding protein, family 5 Pmen_2060 158 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 146307817 Common - hypothetical protein Pmen_2795 12 None None None 146309113 Common - peptidase U32 Pmen_4099 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 146307477 Common - tRNA 2-selenouridine synthase Pmen_2454 65 COG2603 COG2603, Predicted ATPase General function prediction only 146309444 Common - transcriptional regulator, LysR family Pmen_4430 164 COG0583 LysR, Transcriptional regulator Transcription 146305505 Common - GreA/GreB family elongation factor Pmen_0468 13 COG0782 GreA, Transcription elongation factor Transcription 146306469 Common - transcriptional regulator, CdaR Pmen_1437 33 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 146305225 Common - response regulator receiver protein Pmen_0184 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 146308732 Common - RND efflux system, outer membrane lipoprotein, NodT family Pmen_3717 128 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 146309438 Common - flagellar biosynthetic protein FliR Pmen_4424 106 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 146308598 Common - sugar fermentation stimulation protein A Pmen_3583 105 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 146306683 Common - hypothetical protein Pmen_1652 5 None None None 146306892 Common - Citrate transporter Pmen_1861 117 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 146308307 Common - Antibiotic biosynthesis monooxygenase Pmen_3287 27 COG3224 COG3224, Uncharacterized protein conserved in bacteria Function unknown 146306417 Common livM leucine/isoleucine/valine transporter permease subunit Pmen_1385 153 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 146309106 Common - predicted kinase Pmen_4092 56 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 146305920 Common - histidinol-phosphate aminotransferase Pmen_0885 227 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 146309245 Common - FAD linked oxidase domain protein Pmen_4231 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 146306932 Common acnA aconitate hydratase Pmen_1903 222 COG1048 AcnA, Aconitase A Energy production and conversion 146306943 Common - Glutathione S-transferase, N-terminal domain Pmen_1914 120 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 146308220 Common - phosphonate ABC transporter, inner membrane subunit Pmen_3200 85 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 146308674 Common - protein of unknown function DUF1329 Pmen_3659 19 None None None 146307850 Common - PAS/PAC sensor signal transduction histidine kinase Pmen_2828 201 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 146307645 Common - hypothetical protein Pmen_2622 1 None None None 146309144 Common - sarcosine oxidase, delta subunit family Pmen_4130 34 COG4311 SoxD, Sarcosine oxidase delta subunit Amino acid transport and metabolism 146306952 Common queF 7-cyano-7-deazaguanine reductase Pmen_1923 121 COG2904 COG2904, Uncharacterized protein conserved in bacteria Function unknown 146305876 Common - extracellular solute-binding protein, family 5 Pmen_0841 210 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 146306930 Common - protein of unknown function DUF1330 Pmen_1901 13 COG5470 COG5470, Uncharacterized conserved protein Function unknown 146306263 Common - putative aminopeptidase 2 Pmen_1231 44 COG1362 LAP4, Aspartyl aminopeptidase Amino acid transport and metabolism 146306905 Common - glycosyl transferase, family 4 Pmen_1875 82 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 146307638 Common - putative transcriptional regulator, Crp/Fnr family Pmen_2615 142 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 146306486 Common - putative ammonia monooxygenase Pmen_1454 10 COG3180 AbrB, Putative ammonia monooxygenase General function prediction only 146308206 Pathogen - hypothetical protein Pmen_3186 1 None None None 146308689 Common - hypothetical protein Pmen_3674 1 None None None 146305187 Common - hypothetical protein Pmen_0146 8 None None None 146306960 Common - transaldolase B Pmen_1931 184 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 146308140 Common - glucosylglycerol-phosphate synthase Pmen_3120 122 COG0380 OtsA, Trehalose-6-phosphate synthase Carbohydrate transport and metabolism 146309130 Common - hypothetical protein Pmen_4116 32 COG4339 COG4339, Uncharacterized protein conserved in bacteria Function unknown 146305815 Common - N-acetyl-anhydromuranmyl-L-alanine amidase Pmen_0780 110 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 146307387 Common - Acyl-CoA dehydrogenase, type 2, C-terminal domain Pmen_2362 148 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 146308988 Pathogen - hypothetical protein Pmen_3974 2 COG3747 COG3747, Phage terminase, small subunit DNA replication, recombination, and repair 146308030 Common - D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase Pmen_3008 101 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 146308420 Common rpsP 30S ribosomal protein S16 Pmen_3401 208 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 146305500 Common - hypothetical protein Pmen_0463 6 None None None 146305119 Common - nucleoside recognition domain protein Pmen_0078 39 COG2715 SpmA, Uncharacterized membrane protein, required for spore maturation in B.subtilis. General function prediction only 146308018 Common - phosphoribosylaminoimidazole synthetase Pmen_2996 230 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 146306011 Common - putative sulfate transport protein CysZ Pmen_0976 42 COG2981 CysZ, Uncharacterized protein involved in cysteine biosynthesis Amino acid transport and metabolism 146305798 Common - type IV pilus assembly PilZ Pmen_0763 5 None None None 146306474 Common - putative monovalent cation/H+ antiporter subunit C Pmen_1442 96 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 146306580 Common - IS66 Orf2 family protein Pmen_1549 50 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 146305363 Common - protein of unknown function DUF710 Pmen_0322 54 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 146306398 Common - ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components-like protein Pmen_1366 62 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 146307224 Common - cytochrome c, class I Pmen_2197 22 COG4654 COG4654, Cytochrome c551/c552 Energy production and conversion 146307636 Common - coproporphyrinogen III oxidase Pmen_2613 203 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 146306177 Common - ThiJ/PfpI domain protein Pmen_1143 100 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 146309181 Common thiG thiazole synthase Pmen_4167 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 146306537 Common - major facilitator superfamily MFS_1 Pmen_1505 154 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 146305228 Common - flagellar protein FliS Pmen_0187 64 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 146308543 Common - DNA polymerase III chi subunit, HolC Pmen_3528 63 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 146308194 Common - protein of unknown function DUF81 Pmen_3174 63 COG0730 COG0730, Predicted permeases General function prediction only 146305346 Common - polar amino acid ABC transporter, inner membrane subunit Pmen_0305 171 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 146307065 Common - acyl-CoA dehydrogenase domain protein Pmen_2037 166 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 146306195 Common - cation diffusion facilitator family transporter Pmen_1162 147 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 146306477 Common - multiple resistance and pH regulation protein F Pmen_1445 73 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 146308853 Common - protein of unknown function DUF81 Pmen_3839 48 COG0730 COG0730, Predicted permeases General function prediction only 146305835 Common - hypothetical protein Pmen_0800 17 COG3553 COG3553, Uncharacterized protein conserved in bacteria Function unknown 146308560 Common - putative transcriptional regulator, AsnC family Pmen_3545 156 COG1522 Lrp, Transcriptional regulators Transcription 146305584 Common aroK shikimate kinase Pmen_0547 199 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 146305791 Common - DNA repair protein RadA Pmen_0756 212 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 146306078 Common - hypothetical protein Pmen_1043 19 None None None 146308292 Common - protein of unknown function DUF1486 Pmen_3272 17 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 146308139 Common - major facilitator superfamily MFS_1 Pmen_3119 59 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 146306099 Common - hypothetical protein Pmen_1065 14 None None None 146307564 Common - fatty acid desaturase Pmen_2541 26 None None None 146308816 Common nadD nicotinic acid mononucleotide adenyltransferase Pmen_3801 165 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 146308760 Common - pseudouridine synthase Pmen_3745 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 146308923 Common rplC 50S ribosomal protein L3 Pmen_3909 237 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 146308232 Common - glutathione-dependent formaldehyde-activating, GFA Pmen_3212 44 COG3791 COG3791, Uncharacterized conserved protein Function unknown 146306791 Common - transcriptional regulator, MarR family Pmen_1760 33 COG1846 MarR, Transcriptional regulators Transcription 146308910 Common rpsN 30S ribosomal protein S14 Pmen_3896 205 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 146306840 Common - periplasmic protein-like protein Pmen_1809 39 COG3672 COG3672, Predicted periplasmic protein Function unknown 146308484 Common - glutamine amidotransferase, class-II Pmen_3467 238 COG0067 GltB, Glutamate synthase domain 1 Amino acid transport and metabolism 146309059 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Pmen_4045 28 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 146309472 Pathogen - hypothetical protein Pmen_4458 1 None None None 146306845 Common - transcriptional regulator, MarR family Pmen_1814 108 COG1846 MarR, Transcriptional regulators Transcription 146305695 Common - conserved hypothetical protein 730 Pmen_0660 117 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 146308215 Common - Hydroxypyruvate isomerase Pmen_3195 87 COG3622 Hfi, Hydroxypyruvate isomerase Carbohydrate transport and metabolism 146307487 Common - AMP-dependent synthetase and ligase Pmen_2464 218 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 146308752 Common - hypothetical protein Pmen_3737 10 None None None 146306135 Common - transcriptional regulator, TetR family Pmen_1101 42 COG1309 AcrR, Transcriptional regulator Transcription 146305124 Common - two component transcriptional regulator, LuxR family Pmen_0083 211 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 146309496 Common - aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding Pmen_4482 93 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 146308399 Common - urea amidolyase related protein Pmen_3380 115 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 146306278 Common - hypothetical protein Pmen_1246 4 None None None 146307803 Common - anion transporter Pmen_2781 89 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 146307345 Common - putative FHA domain containing protein Pmen_2320 31 COG3456 COG3456, Uncharacterized conserved protein, contains FHA domain Signal transduction mechanisms 146309256 Common - RNA methyltransferase, TrmH family, group 2 Pmen_4242 159 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 146308098 Common - hypothetical protein Pmen_3077 1 None None None 146306784 Common cobD cobalamin biosynthesis protein Pmen_1753 153 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 146308323 Common - TRAP dicarboxylate transporter, DctM subunit Pmen_3303 136 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 146307862 Common flgL flagellar hook-associated protein FlgL Pmen_2840 99 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 146308939 Common - pantothenate kinase Pmen_3925 113 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 146306412 Common - putative signal transduction protein Pmen_1380 36 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 146307259 Common - hypothetical protein Pmen_2233 1 None None None 146307097 Common - enoyl-CoA hydratase Pmen_2069 179 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 146308975 Pathogen - hypothetical protein Pmen_3961 1 None None None 146305406 Common - phosphoesterase, PA-phosphatase related Pmen_0366 14 None None None 146307562 Common - regulatory protein, LuxR Pmen_2539 120 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 146306446 Common - Penicillin amidase Pmen_1414 76 COG2366 COG2366, Protein related to penicillin acylase General function prediction only 146305436 Common pyrC dihydroorotase Pmen_0396 208 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 146306326 Common - peptidyl-prolyl cis-trans isomerase, cyclophilin type Pmen_1294 198 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 146308479 Common - Rh family protein/ammonium transporter Pmen_3462 170 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 146307312 Pathogen - hypothetical protein Pmen_2287 1 None None None 146305722 Common - extracellular solute-binding protein, family 3 Pmen_0687 24 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146308776 Common - hypothetical protein Pmen_3761 13 COG3905 COG3905, Predicted transcriptional regulator Transcription 146306387 Common - pseudouridine synthase Pmen_1355 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 146305960 Common - Polypeptide-transport-associated domain protein, FtsQ-type Pmen_0925 74 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 146308210 Common - extracellular solute-binding protein, family 3 Pmen_3190 12 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146306462 Pathogen - cation antiporter Pmen_1430 1 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 146305332 Common - Lysine exporter protein (LYSE/YGGA) Pmen_0291 86 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 146309619 Common atpC F0F1 ATP synthase subunit epsilon Pmen_4606 167 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 146305593 Common - thioredoxin Pmen_0556 215 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 146305138 Common - ATPase AAA-2 domain protein Pmen_0097 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 146307330 Common - hypothetical protein Pmen_2305 12 None None None 146309293 Common - hypothetical protein Pmen_4279 1 None None None 146307123 Common - nitrite reductase (NAD(P)H), small subunit Pmen_2095 72 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 146307869 Common flgE flagellar hook protein FlgE Pmen_2847 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 146308644 Common - protein of unknown function UPF0125 Pmen_3629 57 COG2914 COG2914, Uncharacterized protein conserved in bacteria Function unknown 146307697 Common - TonB-dependent siderophore receptor Pmen_2675 120 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 146307690 Common - two component transcriptional regulator, LuxR family Pmen_2668 215 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 146308063 Common fabZ (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase Pmen_3042 185 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 146308901 Common rpsM 30S ribosomal protein S13 Pmen_3887 248 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 146305458 Common - cytochrome B561 Pmen_0418 70 COG3038 CybB, Cytochrome B561 Energy production and conversion 146305381 Common - Glutamate--putrescine ligase Pmen_0341 225 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 146305316 Common - hypothetical protein Pmen_0275 6 None None None 146309081 Common - Endonuclease I Pmen_4067 37 COG2356 EndA, Endonuclease I DNA replication, recombination, and repair 146306453 Common - hypothetical protein Pmen_1421 9 None None None 146307760 Common - aromatic amino acid aminotransferase Pmen_2738 71 COG1448 TyrB, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 146307505 Common - amidohydrolase 2 Pmen_2482 9 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 146307712 Common - short-chain dehydrogenase/reductase SDR Pmen_2690 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 146307767 Common - glutaredoxin Pmen_2745 22 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 146309007 Pathogen - hypothetical protein Pmen_3993 1 None None None 146309134 Common - DNA-binding response regulator CreB Pmen_4120 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 146308868 Common ribH riboflavin synthase subunit beta Pmen_3854 230 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 146307998 Common - two component transcriptional regulator, winged helix family Pmen_2976 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 146308572 Common - ABC transporter related Pmen_3557 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 146309266 Common - imidazole glycerol phosphate synthase subunit HisF Pmen_4252 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 146309064 Common - oxidoreductase alpha (molybdopterin) subunit Pmen_4050 169 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 146307832 Common fliR flagellar biosynthesis protein FliR Pmen_2810 128 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 146308312 Common - hypothetical protein Pmen_3292 15 None None None 146308750 Common - short chain dehydrogenase Pmen_3735 238 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 146305823 Common - PTS system, fructose subfamily, IIC subunit Pmen_0788 68 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 146305872 Common dppF dipeptide transporter ATP-binding subunit Pmen_0837 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 146307927 Common - succinylglutamate desuccinylase Pmen_2905 24 COG2988 COG2988, Succinylglutamate desuccinylase Amino acid transport and metabolism 146307263 Pathogen - hypothetical protein Pmen_2237 2 None None None 146307546 Common - hypothetical protein Pmen_2523 5 None None None 146307141 Pathogen - hypothetical protein Pmen_2113 1 None None None 146308722 Common - protein of unknown function DUF461 Pmen_3707 80 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 146306996 Common - pyrroloquinoline quinone biosynthesis protein PqqD Pmen_1968 21 None None None 146305565 Common - poly(R)-hydroxyalkanoic acid synthase, class II Pmen_0528 73 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 146309510 Common - putative ferric uptake regulator, Fur family Pmen_4496 106 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 146308376 Common - peptidase M22, glycoprotease Pmen_3357 180 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 146308458 Common - succinic semialdehyde dehydrogenase Pmen_3441 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 146305464 Common - hypothetical protein Pmen_0424 6 None None None 146309193 Pathogen - hypothetical protein Pmen_4179 1 None None None 146308022 Common - protein of unknown function DUF883, ElaB Pmen_3000 28 COG4575 ElaB, Uncharacterized conserved protein Function unknown 146307980 Common - integral membrane sensor hybrid histidine kinase Pmen_2958 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146305601 Common - restriction modification system DNA specificity domain Pmen_0564 56 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 146308999 Common - hypothetical protein Pmen_3985 1 None None None 146305367 Common - 2-octaprenyl-6-methoxyphenyl hydroxylase Pmen_0326 117 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 146307618 Common - transglutaminase, N-terminal domain protein Pmen_2595 94 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 146307786 Common - permease for cytosine/purine, uracil, thiamine, allantoin Pmen_2764 54 COG1953 FUI1, Cytosine/uracil/thiamine/allantoin permeases Nucleotide transport and metabolism / Coenzyme metabolism 146305851 Common - lipase, class 3 Pmen_0816 18 COG3675 COG3675, Predicted lipase Lipid metabolism 146308436 Common - CMP/dCMP deaminase, zinc-binding Pmen_3417 224 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 146307541 Common - protein of unknown function DUF1287 Pmen_2518 17 COG3738 COG3738, Uncharacterized protein conserved in bacteria Function unknown 146305402 Common - peptidase U61, LD-carboxypeptidase A Pmen_0362 80 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 146308202 Common - protein kinase Pmen_3182 155 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 146307086 Common - binding-protein-dependent transport systems inner membrane component Pmen_2058 221 COG4239 COG4239, ABC-type uncharacterized transport system, permease component General function prediction only 146308154 Common - hypothetical protein Pmen_3134 3 COG0661 AarF, Predicted unusual protein kinase General function prediction only 146309480 Common - Radical SAM domain protein Pmen_4466 104 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 146308255 Common - glucosyltransferase MdoH Pmen_3235 53 COG2943 MdoH, Membrane glycosyltransferase Cell envelope biogenesis, outer membrane 146305772 Common - GCN5-related N-acetyltransferase Pmen_0737 3 COG0456 RimI, Acetyltransferases General function prediction only 146306949 Common - ABC-2 type transporter Pmen_1920 128 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 146306666 Common - type IV pilus assembly PilZ Pmen_1635 33 COG3215 PilZ, Tfp pilus assembly protein PilZ Cell motility and secretion / Intracellular trafficking and secretion 146308886 Common - hypothetical protein Pmen_3872 18 None None None 146306470 Common - Gluconate transporter Pmen_1438 79 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 146308332 Common purU formyltetrahydrofolate deformylase Pmen_3312 222 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 146309047 Common - NERD domain protein Pmen_4033 36 COG0551 TopA, Zn-finger domain associated with topoisomerase type I DNA replication, recombination, and repair 146305060 Common - NLP/P60 protein Pmen_0018 144 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 146306533 Common - Alcohol dehydrogenase, zinc-binding domain protein Pmen_1501 199 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 146305234 Common - OmpA/MotB domain protein Pmen_0193 109 COG1360 MotB, Flagellar motor protein Cell motility and secretion 146308593 Common - cationic amino acid ABC transporter, periplasmic binding protein Pmen_3578 175 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146307438 Common - NADH dehydrogenase subunit E Pmen_2415 157 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 146309555 Common - dihydroorotase Pmen_4541 209 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 146305669 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase Pmen_0634 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 146306110 Common - NAD-dependent epimerase/dehydratase Pmen_1076 105 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 146305802 Common - MOSC domain containing protein Pmen_0767 27 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 146309493 Common - acetyl-CoA carboxylase Pmen_4479 237 COG0439 AccC, Biotin carboxylase Lipid metabolism 146307807 Common - periplasmic protein thiol--disulphide oxidoreductase DsbE Pmen_2785 147 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 146305701 Common ureE urease accessory protein UreE Pmen_0666 62 COG2371 UreE, Urease accessory protein UreE Posttranslational modification, protein turnover, chaperones 146306759 Common - hypothetical protein Pmen_1728 1 None None None 146308253 Common - UvrD/REP helicase Pmen_3233 198 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 146309625 Common - ATP synthase F0, C subunit Pmen_4612 61 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 146306424 Common - dihydroorotase Pmen_1392 91 COG0418 PyrC, Dihydroorotase Nucleotide transport and metabolism 146305916 Common - BolA family protein Pmen_0881 53 COG5007 COG5007, Predicted transcriptional regulator, BolA superfamily Transcription 146306595 Common - response regulator receiver modulated CheB methylesterase Pmen_1564 192 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 146306083 Common - IS66 Orf2 family protein Pmen_1049 50 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 146308802 Common - Rare lipoprotein B Pmen_3787 14 COG2980 RlpB, Rare lipoprotein B Cell envelope biogenesis, outer membrane 146309351 Common - major facilitator superfamily MFS_1 Pmen_4337 103 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 146305966 Common secA preprotein translocase subunit SecA Pmen_0931 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 146305691 Common - protein of unknown function DUF404 Pmen_0656 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 146309188 Common - cell division ATP-binding protein FtsE Pmen_4174 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 146307327 Common - hypothetical protein Pmen_2302 9 None None None 146305883 Common - two component transcriptional regulator, Fis family Pmen_0848 220 COG4567 COG4567, Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain Signal transduction mechanisms / Transcription 146309086 Common - formiminoglutamase Pmen_4072 131 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 146305114 Common - transcriptional regulator, LysR family Pmen_0073 160 COG0583 LysR, Transcriptional regulator Transcription 146309029 Common apaH diadenosine tetraphosphatase Pmen_4015 82 COG0639 ApaH, Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Signal transduction mechanisms 146308125 Common - short-chain dehydrogenase/reductase SDR Pmen_3104 79 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 146305451 Common - amino acid carrier protein Pmen_0411 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 146305768 Common - ABC-type amino acid transport/signal transduction systems periplasmic component/domain-like protein Pmen_0733 18 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146307320 Common - alpha amylase, catalytic region Pmen_2295 86 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 146305546 Common - protein of unknown function DUF924 Pmen_0509 63 COG3803 COG3803, Uncharacterized protein conserved in bacteria Function unknown 146306106 Common - putative transcriptional regulator, MerR family Pmen_1072 37 COG0789 SoxR, Predicted transcriptional regulators Transcription 146306173 Common - 3-oxoacid CoA-transferase, B subunit Pmen_1139 102 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 146308053 Common - Septum formation initiator Pmen_3032 62 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 146309338 Common - NAD(P)H-dependent FMN reductase Pmen_4324 58 COG0431 COG0431, Predicted flavoprotein General function prediction only 146305607 Common - metal dependent phosphohydrolase Pmen_0570 118 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 146309156 Common - hypothetical protein Pmen_4142 15 None None None 146306123 Common - transcriptional regulator, RpiR family Pmen_1089 81 COG1737 RpiR, Transcriptional regulators Transcription 146307858 Common - glycosyl transferase, family 2 Pmen_2836 142 COG1887 TagB, Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC Cell envelope biogenesis, outer membrane 146307483 Common - alpha/beta hydrolase fold Pmen_2460 33 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 146309401 Common - hypothetical protein Pmen_4387 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 146306969 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Pmen_1941 62 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 146307353 Common - GPW/gp25 family protein Pmen_2328 27 COG3518 COG3518, Uncharacterized protein conserved in bacteria Function unknown 146305903 Common - PTS IIA-like nitrogen-regulatory protein PtsN Pmen_0868 135 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 146306354 Common - Alcohol dehydrogenase, zinc-binding domain protein Pmen_1322 176 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 146308690 Common - hypothetical protein Pmen_3675 3 COG3056 COG3056, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 146307649 Common - transcriptional regulator, TetR family Pmen_2626 78 COG1309 AcrR, Transcriptional regulator Transcription 146305323 Common - protein of unknown function DUF513, hemX Pmen_0282 23 COG2959 HemX, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 146308473 Common - glycine cleavage T protein (aminomethyl transferase) Pmen_3456 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 146307395 Common - ATPase AAA-2 domain protein Pmen_2370 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 146308790 Common - hypothetical protein Pmen_3775 1 None None None 146306884 Common cmk cytidylate kinase Pmen_1853 205 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 146307343 Common - protein of unknown function DUF876 Pmen_2318 49 COG3522 COG3522, Uncharacterized protein conserved in bacteria Function unknown 146306438 Common - protein of unknown function DUF59 Pmen_1406 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 146308649 Common - L-lactate transport Pmen_3634 102 COG1620 LldP, L-lactate permease Energy production and conversion 146308640 Common - GrpE protein Pmen_3625 229 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 146308042 Common - peptidase M23B Pmen_3021 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 146309020 Common - hypothetical protein Pmen_4006 4 None None None 146305245 Common - DNA-binding transcriptional dual regulator, glycolate-binding Pmen_0204 137 COG2186 FadR, Transcriptional regulators Transcription 146307931 Common - Arginine N-succinyltransferase Pmen_2909 37 COG3138 AstA, Arginine/ornithine N-succinyltransferase beta subunit Amino acid transport and metabolism 146305679 Common - RNA methyltransferase, TrmH family, group 3 Pmen_0644 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 146305207 Common - hypothetical protein Pmen_0166 21 None None None 146305662 Common - hypothetical protein Pmen_0627 16 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 146305336 Common - hypothetical protein Pmen_0295 83 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 146307872 Common flgB flagellar basal body rod protein FlgB Pmen_2850 86 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 146305962 Common - cell division protein FtsZ Pmen_0927 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 146309331 Common - sulfate ABC transporter, inner membrane subunit CysT Pmen_4317 225 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 146305734 Common - inner-membrane translocator Pmen_0699 155 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 146309050 Common - DNA-cytosine methyltransferase Pmen_4036 131 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 146305221 Common - binding-protein-dependent transport systems inner membrane component Pmen_0180 217 COG4590 COG4590, ABC-type uncharacterized transport system, permease component General function prediction only 146306225 Common - protein of unknown function UPF0027 Pmen_1193 121 COG1690 RtcB, Uncharacterized conserved protein Function unknown 146307240 Common - hypothetical protein Pmen_2213 1 None None None 146307161 Pathogen - protein of unknown function DUF1127 Pmen_2134 1 COG5457 COG5457, Uncharacterized conserved small protein Function unknown 146305360 Common - protein of unknown function DUF55 Pmen_0319 93 COG2947 COG2947, Uncharacterized conserved protein Function unknown 146308871 Common - riboflavin biosynthesis protein RibD Pmen_3857 229 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 146306786 Common - cobyric acid synthase Pmen_1755 150 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 146308680 Common - rRNA (guanine-N(2)-)-methyltransferase Pmen_3665 111 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 146307049 Common - hypothetical protein Pmen_2021 11 None None None 146306349 Common - putative transcriptional regulator, XRE family Pmen_1317 6 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 146307205 Common - 3''-adenylyltransferase Pmen_2178 23 COG1708 COG1708, Predicted nucleotidyltransferases General function prediction only 146306796 Common - integral membrane sensor hybrid histidine kinase Pmen_1765 210 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146309457 Common - sodium-dependent inorganic phosphate (Pi) transporter Pmen_4443 68 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 146305432 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Pmen_0392 33 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 146305991 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase Pmen_0956 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 146308538 Common - putative cold-shock DNA-binding domain protein Pmen_3523 178 COG1278 CspC, Cold shock proteins Transcription 146308167 Common - phospholipid/glycerol acyltransferase Pmen_3147 153 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 146305421 Common - Alcohol dehydrogenase Pmen_0381 158 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 146307657 Common - Glutamate--putrescine ligase Pmen_2634 226 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 146305531 Common - protein of unknown function DUF224, cysteine-rich region domain protein Pmen_0494 86 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 146306624 Common - transcription-repair coupling factor Pmen_1593 233 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 146306586 Common - hypothetical protein Pmen_1555 15 COG3219 COG3219, Uncharacterized protein conserved in bacteria Function unknown 146308653 Common - transposase IS66 Pmen_3638 67 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 146309296 Common - Beta-xylosidase-like protein Pmen_4282 11 COG3664 XynB, Beta-xylosidase Carbohydrate transport and metabolism 146307061 Common - acyl-CoA dehydrogenase domain protein Pmen_2033 170 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 146309123 Common - peptidase S8 and S53, subtilisin, kexin, sedolisin Pmen_4109 119 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 146309035 Common cca multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase Pmen_4021 191 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 146307867 Common flgG flagellar basal body rod protein FlgG Pmen_2845 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 146305598 Common - acyl-CoA dehydrogenase domain protein Pmen_0561 147 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 146306554 Common - major facilitator superfamily MFS_1 Pmen_1523 30 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 146308798 Common lnt apolipoprotein N-acyltransferase Pmen_3783 164 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 146306208 Common - efflux transporter, RND family, MFP subunit Pmen_1176 171 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 146307369 Common - hypothetical protein Pmen_2344 1 None None None 146309219 Common - dihydroxy-acid dehydratase Pmen_4205 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 146308084 Common - ABC-type amino acid transport/signal transduction systems periplasmic component/domain-like protein Pmen_3063 18 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146308848 Common - Amidohydrolase 3 Pmen_3834 69 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 146305948 Common - hypothetical protein Pmen_0913 144 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 146306303 Common ruvA Holliday junction DNA helicase motor protein Pmen_1271 208 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 146309175 Common - hypothetical protein Pmen_4161 2 None None None 146307072 Common - binding-protein-dependent transport systems inner membrane component Pmen_2044 150 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 146307840 Common - Hpt protein Pmen_2818 31 COG2198 ArcB, FOG: HPt domain Signal transduction mechanisms 146306982 Common - Glucose/sorbosone dehydrogenase-like protein Pmen_1954 62 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 146308422 Common - cytochrome c assembly protein Pmen_3403 63 COG4137 COG4137, ABC-type uncharacterized transport system, permease component General function prediction only 146307898 Common - indolepyruvate ferredoxin oxidoreductase Pmen_2876 94 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 146309381 Common - methyl-accepting chemotaxis sensory transducer Pmen_4367 139 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146306431 Common - SoxR-reducing system protein RsxE Pmen_1399 76 COG4660 RnfE, Predicted NADH:ubiquinone oxidoreductase, subunit RnfE Energy production and conversion 146307683 Common - Alpha/beta hydrolase fold-3 domain protein Pmen_2661 132 COG0657 Aes, Esterase/lipase Lipid metabolism 146307901 Common - phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN Pmen_2879 97 COG3709 COG3709, Uncharacterized component of phosphonate metabolism Inorganic ion transport and metabolism 146309306 Common - dTDP-4-dehydrorhamnose reductase Pmen_4292 166 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 146308440 Pathogen - hypothetical protein Pmen_3421 1 None None None 146307456 Common - protein of unknown function DUF490 Pmen_2433 88 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 146307860 Common - HAD-superfamily hydrolase, subfamily IB (PSPase-like) Pmen_2838 63 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 146306163 Common - beta-lactamase Pmen_1129 78 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 146308225 Common - short-chain dehydrogenase/reductase SDR Pmen_3205 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 146307470 Common - CHAD domain containing protein Pmen_2447 1 COG5607 COG5607, Uncharacterized conserved protein Function unknown 146307519 Common - membrane protein-like protein Pmen_2496 34 COG3686 COG3686, Predicted membrane protein Function unknown 146308235 Common - short-chain dehydrogenase/reductase SDR Pmen_3215 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 146307572 Common - 2-dehydropantoate 2-reductase Pmen_2549 75 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 146309286 Common - polar amino acid ABC transporter, inner membrane subunit Pmen_4272 172 COG4160 ArtM, ABC-type arginine/histidine transport system, permease component Amino acid transport and metabolism 146309568 Common - hypothetical protein Pmen_4554 5 None None None 146306094 Common prfA peptide chain release factor 1 Pmen_1060 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 146308520 Common - protein of unknown function DUF528 Pmen_3505 43 COG2975 COG2975, Uncharacterized protein conserved in bacteria Function unknown 146309302 Common - sugar transferase Pmen_4288 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 146308412 Common - threonine synthase Pmen_3393 137 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 146306201 Common - outer membrane porin Pmen_1168 10 None None None 146306828 Common - putative agmatinase Pmen_1797 160 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 146306703 Common - membrane bound O-acyl transferase, MBOAT family protein Pmen_1672 86 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 146308956 Common - OsmC family protein Pmen_3942 86 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 146306052 Pathogen - hypothetical protein Pmen_1017 1 None None None 146307883 Common - ferric iron reductase Pmen_2861 19 COG4114 FhuF, Uncharacterized Fe-S protein General function prediction only 146308810 Common - rare lipoprotein A Pmen_3795 136 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 146306578 Common - hypothetical protein Pmen_1547 4 None None None 146306150 Common - chromosome replication initiation inhibitor protein Pmen_1116 98 COG0583 LysR, Transcriptional regulator Transcription 146305262 Common - major facilitator superfamily MFS_1 Pmen_0221 76 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 146308658 Common - hypothetical protein Pmen_3643 14 None None None 146309253 Common - helix-turn-helix- domain containing protein, AraC type Pmen_4239 64 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 146307705 Common - Ethanolamine ammonia-lyase Pmen_2683 53 COG4302 EutC, Ethanolamine ammonia-lyase, small subunit Amino acid transport and metabolism 146307800 Common - efflux transporter, RND family, MFP subunit Pmen_2778 84 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 146305350 Common rho transcription termination factor Rho Pmen_0309 204 COG1158 Rho, Transcription termination factor Transcription 146306843 Common - ATP-dependent DNA helicase RecQ Pmen_1812 222 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 146309450 Common - hypothetical protein Pmen_4436 2 None None None 146306367 Common - protein of unknown function DUF899, thioredoxin family protein Pmen_1335 28 COG4312 COG4312, Uncharacterized protein conserved in bacteria Function unknown 146305392 Common - phosphate transporter Pmen_0352 173 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 146308885 Common - MotA/TolQ/ExbB proton channel Pmen_3871 20 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 146308408 Common - phage shock protein A, PspA Pmen_3389 52 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 146305106 Common - transcriptional regulator, LysR family Pmen_0065 181 COG0583 LysR, Transcriptional regulator Transcription 146307951 Common - ATPase associated with various cellular activities, AAA_3 Pmen_2929 174 COG0714 COG0714, MoxR-like ATPases General function prediction only 146307219 Common - hypothetical protein Pmen_2192 28 COG5579 COG5579, Uncharacterized conserved protein Function unknown 146308294 Common - intracellular protease, PfpI family Pmen_3274 131 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 146305156 Common - hypothetical protein Pmen_0115 19 COG3495 COG3495, Uncharacterized protein conserved in bacteria Function unknown 146308419 Common rimM 16S rRNA-processing protein Pmen_3400 187 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 146309343 Common - ABC transporter related Pmen_4329 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 146306359 Common - HAD-superfamily subfamily IB hydrolase, TIGR01490 Pmen_1327 84 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 146308497 Common - phage transcriptional regulator, AlpA Pmen_3482 15 COG3311 AlpA, Predicted transcriptional regulator Transcription 146308104 Pathogen - hypothetical protein Pmen_3083 2 None None None 146305578 Common - penicillin-binding protein, 1A family Pmen_0541 200 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 146306688 Common - amidase Pmen_1657 211 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 146305522 Common - Substrate-binding region of ABC-type glycine betaine transport system Pmen_0485 67 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 146306656 Common rpmF 50S ribosomal protein L32 Pmen_1625 95 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 146308366 Common - transcriptional regulator, DeoR family Pmen_3347 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 146306649 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase Pmen_1618 187 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 146307210 Common - transcriptional regulator, LysR family Pmen_2183 94 COG0583 LysR, Transcriptional regulator Transcription 146309415 Common - histone family protein DNA-binding protein Pmen_4401 210 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 146309467 Common - OsmC family protein Pmen_4453 82 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 146308786 Common - major facilitator superfamily MFS_1 Pmen_3771 7 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 146308985 Common - peptidase S14, ClpP Pmen_3971 41 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 146305412 Common - ABC transporter related Pmen_0372 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 146307031 Common - ABC transporter related Pmen_2003 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 146308511 Common engA GTP-binding protein EngA Pmen_3496 229 COG1160 COG1160, Predicted GTPases General function prediction only 146308356 Common - hypothetical protein Pmen_3337 25 None None None 146306381 Common - hypothetical protein Pmen_1349 1 None None None 146305302 Common - protein of unknown function UPF0047 Pmen_0261 128 COG0432 COG0432, Uncharacterized conserved protein Function unknown 146308630 Common - ATP-dependent metalloprotease FtsH Pmen_3615 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 146308438 Pathogen - hypothetical protein Pmen_3419 1 None None None 146307007 Common rplT 50S ribosomal protein L20 Pmen_1979 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 146306917 Common - methylated-DNA--protein-cysteine methyltransferase Pmen_1887 218 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 146307188 Common - HesB/YadR/YfhF-family protein Pmen_2161 93 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 146305956 Common - cell division protein FtsW Pmen_0921 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 146306573 Common - ATPase/kinase involved in NAD metabolism-like protein Pmen_1542 30 COG3172 NadR, Predicted ATPase/kinase involved in NAD metabolism Coenzyme metabolism 146306925 Common - GCN5-related N-acetyltransferase Pmen_1896 161 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 146308076 Common glnD PII uridylyl-transferase Pmen_3055 124 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 146309015 Common - binding-protein-dependent transport systems inner membrane component Pmen_4001 156 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 146306336 Common - hypothetical protein Pmen_1304 6 None None None 146305074 Common - sigma54 specific transcriptional regulator, Fis family Pmen_0032 167 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 146306519 Common - 2OG-Fe(II) oxygenase Pmen_1487 42 COG3145 AlkB, Alkylated DNA repair protein DNA replication, recombination, and repair 146306605 Pathogen - hypothetical protein Pmen_1574 2 None None None 146306810 Pathogen - hypothetical protein Pmen_1779 1 COG5373 COG5373, Predicted membrane protein Function unknown 146306972 Common - hypothetical protein Pmen_1944 15 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 146307178 Common - diguanylate cyclase/phosphodiesterase Pmen_2151 176 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 146306510 Common - pyridoxal phosphate biosynthetic protein PdxJ Pmen_1478 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 146308580 Common - ATP-dependent RNA helicase RhlB Pmen_3565 228 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 146307404 Common - hypothetical protein Pmen_2381 185 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 146308160 Common - aldo/keto reductase Pmen_3140 160 COG4989 COG4989, Predicted oxidoreductase General function prediction only 146309099 Common - biotin biosynthesis protein BioC Pmen_4085 183 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 146309434 Pathogen - surface presentation of antigens (SPOA) protein Pmen_4420 6 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 146308173 Common - hypothetical protein Pmen_3153 3 None None None 146305217 Common - two component, sigma54 specific, transcriptional regulator, Fis family Pmen_0176 205 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 146308166 Common - small multidrug resistance protein Pmen_3146 138 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 146307673 Common - histone family protein DNA-binding protein Pmen_2651 135 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 146308665 Common - OmpA/MotB domain protein Pmen_3650 170 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 146305808 Common - Prepilin peptidase Pmen_0773 126 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 146305717 Common - Molecular chaperone-like protein Pmen_0682 231 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 146306022 Common - carboxynorspermidine decarboxylase Pmen_0987 58 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 146306374 Common - NADPH-dependent FMN reductase Pmen_1342 44 COG0431 COG0431, Predicted flavoprotein General function prediction only 146305938 Common - ubiquinol-cytochrome c reductase, iron-sulfur subunit Pmen_0903 91 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 146305818 Common - hydrolase, TatD family Pmen_0783 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 146309586 Common cobH precorrin-8X methylmutase Pmen_4572 118 COG2082 CobH, Precorrin isomerase Coenzyme metabolism 146306157 Common - ATPase, P-type (transporting), HAD superfamily, subfamily IC Pmen_1123 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 146308978 Pathogen - hypothetical protein Pmen_3964 1 None None None 146305491 Common - S-adenosylmethionine synthetase Pmen_0454 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 146309076 Common - MotA/TolQ/ExbB proton channel Pmen_4062 149 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 146305161 Common - Alcohol dehydrogenase GroES domain protein Pmen_0120 212 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 146308179 Common - transcriptional regulator, LysR family Pmen_3159 153 COG0583 LysR, Transcriptional regulator Transcription 146307796 Common - Urea transporter Pmen_2774 2 COG4413 Utp, Urea transporter Amino acid transport and metabolism 146305843 Common - hypothetical protein Pmen_0808 22 COG3553 COG3553, Uncharacterized protein conserved in bacteria Function unknown 146307252 Common - Heavy metal transport/detoxification protein Pmen_2225 30 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 146305397 Common - thioesterase superfamily protein Pmen_0357 107 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 146305143 Common - protein of unknown function DUF876 Pmen_0102 49 COG3522 COG3522, Uncharacterized protein conserved in bacteria Function unknown 146305141 Common - putative FHA domain containing protein Pmen_0100 23 COG3456 COG3456, Uncharacterized conserved protein, contains FHA domain Signal transduction mechanisms 146306760 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Pmen_1729 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 146309139 Common - phospholipid/glycerol acyltransferase Pmen_4125 29 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 146308822 Common - peptidase S16, lon domain protein Pmen_3807 41 COG2802 COG2802, Uncharacterized protein, similar to the N-terminal domain of Lon protease General function prediction only 146308639 Common - chaperone protein DnaK Pmen_3624 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 146307452 Common - acriflavin resistance protein Pmen_2429 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 146307317 Common - CBS domain containing protein Pmen_2292 149 COG0517 COG0517, FOG: CBS domain General function prediction only 146306507 Common rnc ribonuclease III Pmen_1475 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 146307596 Common - peptidyl-prolyl cis-trans isomerase, cyclophilin type Pmen_2573 200 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 146305108 Common - transcriptional regulator, LysR family Pmen_0067 150 COG0583 LysR, Transcriptional regulator Transcription 146308616 Common - hypothetical protein Pmen_3601 4 None None None 146307309 Common - Endonuclease/exonuclease/phosphatase Pmen_2284 47 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 146307841 Common - response regulator receiver protein Pmen_2819 223 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 146306287 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pmen_1255 9 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 146307382 Common - short chain dehydrogenase Pmen_2357 190 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 146308040 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Pmen_3019 136 COG1146 COG1146, Ferredoxin Energy production and conversion 146306641 Common - hypothetical protein Pmen_1610 41 COG3216 COG3216, Uncharacterized protein conserved in bacteria Function unknown 146308627 Common tpiA triosephosphate isomerase Pmen_3612 221 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 146307380 Common - pyruvate decarboxylase Pmen_2355 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 146309121 Common - hypothetical protein Pmen_4107 29 COG4452 CreD, Inner membrane protein involved in colicin E2 resistance Defense mechanisms 146306068 Common - PhoH family protein Pmen_1033 199 COG1875 COG1875, Predicted ATPase related to phosphate starvation-inducible protein PhoH Signal transduction mechanisms 146307443 Common - NADH dehydrogenase subunit J Pmen_2420 26 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 146309623 Common - ATP synthase F1, delta subunit Pmen_4610 171 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 146306719 Common - NAD(P)H dehydrogenase (quinone) Pmen_1688 76 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 146307389 Common - NLPA lipoprotein Pmen_2364 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 146305611 Common - hypothetical protein Pmen_0574 3 None None None 146309223 Common - Dihydrofolate reductase Pmen_4209 145 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 146306695 Common - Uncharacterized lipoprotein-like protein Pmen_1664 28 COG3317 NlpB, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 146305210 Common - multi-sensor hybrid histidine kinase Pmen_0169 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146305064 Pathogen - hypothetical protein Pmen_0022 1 None None None 146305151 Common - hypothetical protein Pmen_0110 3 None None None 146307009 Common pheT phenylalanyl-tRNA synthetase subunit beta Pmen_1981 244 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 146305057 Common - DNA-3-methyladenine glycosylase I Pmen_0015 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 146305973 Common - response regulator receiver modulated diguanylate cyclase Pmen_0938 148 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 146308363 Common - phenazine biosynthesis protein PhzF family Pmen_3344 122 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 146305971 Common - multi-sensor signal transduction histidine kinase Pmen_0936 222 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 146306529 Common - major facilitator superfamily MFS_1 Pmen_1497 85 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 146306370 Common - peptidase M14, carboxypeptidase A Pmen_1338 26 COG2866 COG2866, Predicted carboxypeptidase Amino acid transport and metabolism 146308119 Common - diguanylate phosphodiesterase Pmen_3098 162 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 146309605 Common - hypothetical protein Pmen_4591 22 None None None 146309001 Pathogen - hypothetical protein Pmen_3987 1 None None None 146307749 Common - dihydrouridine synthase, DuS Pmen_2727 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 146308353 Common - hypothetical protein Pmen_3334 19 None None None 146307479 Common - Patatin Pmen_2456 127 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 146306170 Common - regulatory protein, LuxR Pmen_1136 108 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 146308284 Common - diguanylate cyclase Pmen_3264 177 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 146305219 Common - hypothetical protein Pmen_0178 16 None None None 146305745 Common - putative TIM-barrel protein, nifR3 family Pmen_0710 210 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 146306246 Common - Glucarate dehydratase Pmen_1214 54 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 146305494 Common - C4-dicarboxylate transporter/malic acid transport protein Pmen_0457 41 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 146307420 Common - isocitrate dehydrogenase, NADP-dependent Pmen_2397 65 COG2838 Icd, Monomeric isocitrate dehydrogenase Energy production and conversion 146307966 Common ppnK inorganic polyphosphate/ATP-NAD kinase Pmen_2944 240 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 146305330 Common - ABC transporter related Pmen_0289 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 146307762 Common - Citrate transporter Pmen_2740 74 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 146307429 Common - NolW domain protein Pmen_2406 11 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 146307108 Common prpB 2-methylisocitrate lyase Pmen_2080 136 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 146305793 Common - hypothetical protein Pmen_0758 12 None None None 146305095 Common fmt methionyl-tRNA formyltransferase Pmen_0054 221 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 146306030 Common - ABC transporter related Pmen_0995 249 COG4559 COG4559, ABC-type hemin transport system, ATPase component Inorganic ion transport and metabolism 146309504 Common - Peptidoglycan-binding LysM Pmen_4490 4 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 146307135 Pathogen - hypothetical protein Pmen_2107 1 None None None 146306137 Common - drug resistance transporter, Bcr/CflA subfamily Pmen_1103 164 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 146307878 Common - type IV pilus assembly PilZ Pmen_2856 6 COG5581 COG5581, Predicted glycosyltransferase Cell envelope biogenesis, outer membrane 146308282 Common - Enoyl-CoA hydratase/isomerase Pmen_3262 173 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 146305374 Common - protein of unknown function DUF395, YeeE/YedE Pmen_0334 57 COG2391 COG2391, Predicted transporter component General function prediction only 146308470 Common - hypothetical protein Pmen_3453 12 None None None 146306323 Common - two component transcriptional regulator, LuxR family Pmen_1291 190 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 146306512 Pathogen - hypothetical protein Pmen_1480 1 None None None 146309579 Common - periplasmic binding protein Pmen_4565 119 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 146307106 Common - protein of unknown function DUF785 Pmen_2078 33 COG4067 COG4067, Uncharacterized protein conserved in archaea Posttranslational modification, protein turnover, chaperones 146305560 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase Pmen_0523 224 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 146308269 Common - hypothetical protein Pmen_3249 28 COG2912 COG2912, Uncharacterized conserved protein Function unknown 146309176 Common - Carbohydrate-binding, CenC domain protein domain protein Pmen_4162 8 None None None 146306677 Common - diguanylate cyclase with PAS/PAC sensor Pmen_1646 192 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 146308004 Common - Nitrate reductase cytochrome c-type subunit (NapB) Pmen_2982 37 COG3043 NapB, Nitrate reductase cytochrome c-type subunit Energy production and conversion 146305322 Common - uroporphyrinogen-III synthase Pmen_0281 54 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 146307401 Common - hypothetical protein Pmen_2378 38 COG2923 DsrF, Uncharacterized protein involved in the oxidation of intracellular sulfur Inorganic ion transport and metabolism 146305684 Common - replicative DNA helicase Pmen_0649 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 146308112 Common - glycerol-3-phosphate acyltransferase Pmen_3091 48 COG2937 PlsB, Glycerol-3-phosphate O-acyltransferase Lipid metabolism 146305258 Common - hypothetical protein Pmen_0217 8 None None None 146305562 Common - poly(hydroxyalkanoate) granule-associated protein Pmen_0525 6 None None None 146306185 Common - binding-protein-dependent transport systems inner membrane component Pmen_1151 140 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 146308275 Common - extracellular solute-binding protein, family 3 Pmen_3255 54 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146305719 Common - membrane protein-like protein Pmen_0684 97 COG1238 COG1238, Predicted membrane protein Function unknown 146308865 Common - phosphatidylglycerophosphatase A Pmen_3851 105 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 146306441 Pathogen - hypothetical protein Pmen_1409 1 None None None 146307703 Common - orotidine 5'-phosphate decarboxylase Pmen_2681 154 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 146308449 Common - protein of unknown function UPF0153 Pmen_3430 8 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 146306361 Common - binding-protein-dependent transport systems inner membrane component Pmen_1329 67 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 146306029 Common - transport system permease protein Pmen_0994 125 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 146308608 Common panC pantoate--beta-alanine ligase Pmen_3593 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 146308006 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Pmen_2984 123 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 146305253 Common flgH flagellar basal body L-ring protein Pmen_0212 99 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 146305337 Common - isoprenoid biosynthesis protein with amidotransferase-like domain Pmen_0296 39 COG3155 ElbB, Uncharacterized protein involved in an early stage of isoprenoid biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 146307337 Common - ABC transporter related Pmen_2312 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 146306061 Common - Carbohydrate-binding and sugar hydrolysis Pmen_1026 9 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 146306216 Common - hypothetical protein Pmen_1184 20 None None None 146307736 Common - FolC bifunctional protein Pmen_2714 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 146307310 Common - cardiolipin synthase 2 Pmen_2285 148 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 146309518 Common - binding-protein-dependent transport systems inner membrane component Pmen_4504 100 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 146306018 Common - hypothetical protein Pmen_0983 3 None None None 146308489 Common - FAD dependent oxidoreductase Pmen_3472 130 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 146308651 Common - D-lactate dehydrogenase Pmen_3636 51 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 146305673 Common - HflC protein Pmen_0638 127 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 146307685 Common - hypothetical protein Pmen_2663 24 COG3224 COG3224, Uncharacterized protein conserved in bacteria Function unknown 146307554 Common - Phosphoglycerate mutase Pmen_2531 25 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 146306567 Pathogen - hypothetical protein Pmen_1536 1 COG4304 COG4304, Uncharacterized protein conserved in bacteria Function unknown 146305989 Common lspA lipoprotein signal peptidase Pmen_0954 95 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 146305555 Common - twin-arginine translocation protein, TatA/E family subunit Pmen_0518 21 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 146308725 Common - hypothetical protein Pmen_3710 1 None None None 146306835 Common - type I secretion outer membrane protein, TolC family Pmen_1804 130 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 146307472 Common - protein of unknown function DUF58 Pmen_2449 48 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 146307627 Common - cytochrome c oxidase, cbb3-type, subunit I Pmen_2604 135 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 146306890 Common - Serine acetyltransferase-like protein Pmen_1859 216 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 146307976 Common - transcriptional regulator, MarR family Pmen_2954 23 COG1846 MarR, Transcriptional regulators Transcription 146306741 Common nfrB bacteriophage N4 adsorption protein B Pmen_1710 16 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 146305528 Common - hypothetical protein Pmen_0491 2 None None None 146307194 Common - hypothetical protein Pmen_2167 22 None None None 146305344 Common - ABC transporter related Pmen_0303 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 146307112 Common - hypothetical protein Pmen_2084 113 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 146305274 Common - hypothetical protein Pmen_0233 4 None None None 146305892 Common - rod shape-determining protein MreC Pmen_0857 146 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 146306088 Common - 50S ribosomal protein L25/general stress protein Ctc Pmen_1054 193 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 146306344 Common - phosphogluconate dehydratase Pmen_1312 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 146306521 Pathogen - hypothetical protein Pmen_1489 1 None None None 146307494 Common - methyl-accepting chemotaxis sensory transducer Pmen_2471 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 146305553 Common - Sec-independent protein translocase, TatC subunit Pmen_0516 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 146306132 Common - extracellular solute-binding protein, family 3 Pmen_1098 174 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146305629 Common - lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA Pmen_0594 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 146308136 Common - binding-protein-dependent transport systems inner membrane component Pmen_3116 139 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 146308465 Common - binding-protein-dependent transport systems inner membrane component Pmen_3448 208 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 146306907 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Pmen_1877 62 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 146308930 Common rpoB DNA-directed RNA polymerase subunit beta Pmen_3916 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 146309324 Common - response regulator receiver protein Pmen_4310 176 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 146305171 Common - putative transcriptional regulator, GntR family Pmen_0130 175 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 146305189 Common - hypothetical protein Pmen_0148 26 None None None 146306509 Common recO DNA repair protein RecO Pmen_1477 61 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 146307051 Common - Sua5/YciO/YrdC/YwlC family protein Pmen_2023 239 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 146307774 Common - Xanthine dehydrogenase Pmen_2752 112 COG4631 XdhB, Xanthine dehydrogenase, molybdopterin-binding subunit B Nucleotide transport and metabolism 146307291 Common - cytochrome c, monohaem Pmen_2266 159 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 146307534 Common - 6-phosphogluconate dehydrogenase, NAD-binding Pmen_2511 196 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 146305477 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Pmen_0439 62 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 146308188 Common - NAD(P)H dehydrogenase (quinone) Pmen_3168 43 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 146306593 Common - lipid kinase Pmen_1562 111 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 146309459 Common - TRAP transporter, 4TM/12TM fusion protein Pmen_4445 108 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 146307302 Common glgA glycogen synthase Pmen_2277 139 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 146309153 Common - thiamine biosynthesis protein ThiI Pmen_4139 95 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 146309589 Common - transcriptional regulator, AraC family Pmen_4575 119 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 146307379 Common - UDP-glucose 6-dehydrogenase Pmen_2354 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 146306729 Common - fumarylacetoacetate (FAA) hydrolase Pmen_1698 62 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 146306745 Common - cytochrome B561 Pmen_1714 92 COG3038 CybB, Cytochrome B561 Energy production and conversion 146305177 Common - Asparaginase Pmen_0136 102 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 146305980 Common - uracil-xanthine permease Pmen_0945 126 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 146305864 Common - protein of unknown function DUF411 Pmen_0829 64 COG3019 COG3019, Predicted metal-binding protein General function prediction only 146307584 Common - transcription elongation factor GreB Pmen_2561 194 COG0782 GreA, Transcription elongation factor Transcription 146309146 Common - serine hydroxymethyltransferase Pmen_4132 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 146308248 Common - acetyl-CoA acetyltransferase Pmen_3228 174 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 146308212 Common - major facilitator superfamily MFS_1 Pmen_3192 147 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 146309101 Common - 8-amino-7-oxononanoate synthase Pmen_4087 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 146305740 Common - multiple antibiotic resistance (MarC)-related protein Pmen_0705 158 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 146307711 Common - protein of unknown function DUF1446 Pmen_2689 35 None None None 146309377 Common - major facilitator superfamily MFS_1 Pmen_4363 85 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 146306074 Common - protein of unknown function DUF6, transmembrane Pmen_1039 152 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 146305783 Common - hypothetical protein Pmen_0748 4 None None None 146306304 Common ruvB Holliday junction DNA helicase B Pmen_1272 215 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 146307569 Common cysB transcriptional regulator CysB Pmen_2546 188 COG0583 LysR, Transcriptional regulator Transcription 146307631 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Pmen_2608 77 COG0348 NapH, Polyferredoxin Energy production and conversion 146308137 Common - ABC transporter related Pmen_3117 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 146308486 Common - transcriptional regulator, XRE family Pmen_3469 109 COG1396 HipB, Predicted transcriptional regulators Transcription 146307063 Common - short-chain dehydrogenase/reductase SDR Pmen_2035 227 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 146309040 Common rpsU 30S ribosomal protein S21 Pmen_4026 90 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 146309027 Common ksgA dimethyladenosine transferase Pmen_4013 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 146306276 Common - short chain dehydrogenase Pmen_1244 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 146308039 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Pmen_3018 62 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 146309562 Common - choline/carnitine/betaine transporter Pmen_4548 95 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 146308230 Common - major facilitator superfamily MFS_1 Pmen_3210 206 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 146308925 Common - elongation factor Tu Pmen_3911 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 146307489 Common - hypothetical protein Pmen_2466 3 None None None 146307750 Pathogen - hypothetical protein Pmen_2728 3 None None None 146305126 Common - TRAP dicarboxylate transporter- DctP subunit Pmen_0085 114 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 146308704 Common - Mn2+-dependent serine/threonine protein kinase Pmen_3689 7 COG3642 COG3642, Mn2+-dependent serine/threonine protein kinase Signal transduction mechanisms 146308217 Common - phosphonate ABC transporter, periplasmic phosphonate-binding protein Pmen_3197 93 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 146307905 Common - phosphonate metabolism PhnJ Pmen_2883 45 COG3627 PhnJ, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 146305774 Common - hypothetical protein Pmen_0739 1 None None None 146308941 Common - tyrosyl-tRNA synthetase Pmen_3927 239 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 146309360 Common - sulfate ABC transporter, inner membrane subunit CysT Pmen_4346 237 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 146306450 Common - hypothetical protein Pmen_1418 6 None None None 146309499 Common - transcriptional regulator, RpiR family Pmen_4485 87 COG1737 RpiR, Transcriptional regulators Transcription 146307231 Common - transcriptional regulator, LysR family Pmen_2204 187 COG0583 LysR, Transcriptional regulator Transcription 146308575 Common - extracellular solute-binding protein, family 3 Pmen_3560 110 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146308748 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pmen_3733 68 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 146308738 Common - aminotransferase, class V Pmen_3723 117 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 146308874 Common - Methyltransferase type 12 Pmen_3860 29 COG3897 COG3897, Predicted methyltransferase General function prediction only 146306448 Common - SEC-C motif domain protein Pmen_1416 33 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 146307440 Common - NADH dehydrogenase subunit G Pmen_2417 183 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 146308804 Common - protein of unknown function DUF331 Pmen_3789 1 COG3036 COG3036, Uncharacterized protein conserved in bacteria Function unknown 146306553 Common - glyceraldehyde-3-phosphate dehydrogenase Pmen_1522 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 146306954 Common - phosphatase/phosphohexomutase-like protein Pmen_1925 15 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 146306324 Common - transcriptional regulator, LysR family Pmen_1292 192 COG0583 LysR, Transcriptional regulator Transcription 146307125 Common - protein kinase Pmen_2097 159 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 146306410 Common - transcriptional regulator, AraC family Pmen_1378 120 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 146308397 Common - hypothetical protein Pmen_3378 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 146308326 Common - Aldose 1-epimerase Pmen_3306 23 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 146305724 Common - PEP phosphonomutase and related enzymes-like protein Pmen_0689 113 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 146306464 Common - NADH-ubiquinone oxidoreductase, chain 4L Pmen_1432 10 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 146305582 Common - Pilus assembly protein, PilQ Pmen_0545 37 COG3168 PilP, Tfp pilus assembly protein PilP Cell motility and secretion / Intracellular trafficking and secretion 146305751 Common dipZ thiol:disulfide interchange protein precursor Pmen_0716 80 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 146307238 Common - efflux transporter, RND family, MFP subunit Pmen_2211 165 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 146305362 Common - 5-formyltetrahydrofolate cyclo-ligase Pmen_0321 51 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 146305487 Common - membrane protein-like protein Pmen_0450 26 COG3686 COG3686, Predicted membrane protein Function unknown 146307699 Common - Lysine exporter protein (LYSE/YGGA) Pmen_2677 110 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 146309542 Common - thioesterase superfamily protein Pmen_4528 139 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 146306404 Common - PEP phosphonomutase and related enzymes-like protein Pmen_1372 97 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 146308456 Common - aldehyde dehydrogenase Pmen_3439 222 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 146305591 Common - UspA domain protein Pmen_0554 49 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 146309367 Common - putative transcriptional regulator, Crp/Fnr family Pmen_4353 36 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 146306793 Common - glutathione peroxidase Pmen_1762 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 146308392 Common - glucose-methanol-choline oxidoreductase Pmen_3373 89 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 146309295 Common - glycosyl transferase, group 1 Pmen_4281 100 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 146305589 Common hemE uroporphyrinogen decarboxylase Pmen_0552 180 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 146308906 Common rpsE 30S ribosomal protein S5 Pmen_3892 247 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 146307892 Common - amino acid adenylation domain Pmen_2870 222 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 146307095 Common - DNA polymerase III subunit epsilon Pmen_2067 190 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 146306299 Common - metal dependent phosphohydrolase Pmen_1267 128 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 146305809 Common - type II secretion system protein Pmen_0774 143 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 146307372 Common - (2Fe-2S)-binding domain protein Pmen_2347 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 146308948 Common - conserved hypothetical protein 701 Pmen_3934 95 COG1981 COG1981, Predicted membrane protein Function unknown 146308569 Common - Phosphatidylcholine synthase Pmen_3554 23 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 146307957 Common - Patched family protein Pmen_2935 57 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 146309243 Common - SdiA-regulated domain protein Pmen_4229 11 COG3204 COG3204, Uncharacterized protein conserved in bacteria Function unknown 146308915 Common - 50S ribosomal protein L29 Pmen_3901 92 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 146308301 Common - hypothetical protein Pmen_3281 71 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 146308855 Common - Polyprenyl synthetase Pmen_3841 241 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 146308961 Pathogen - hypothetical protein Pmen_3947 1 None None None 146309108 Common - amino acid-binding ACT domain protein Pmen_4094 30 COG2716 GcvR, Glycine cleavage system regulatory protein Amino acid transport and metabolism 146306047 Common - putative sulfite oxidase subunit YedZ Pmen_1012 27 COG2717 COG2717, Predicted membrane protein Function unknown 146307223 Common - exonuclease of the beta-lactamase fold involved in RNA processing-like protein Pmen_2196 54 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 146308383 Common - hypothetical protein Pmen_3364 2 None None None 146307608 Pathogen - hypothetical protein Pmen_2585 1 None None None 146306941 Common - protein of unknown function DUF815 Pmen_1912 89 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 146307675 Common - diguanylate cyclase/phosphodiesterase Pmen_2653 171 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 146306415 Common - ABC transporter related Pmen_1383 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 146305434 Common - 3'(2'),5'-bisphosphate nucleotidase Pmen_0394 187 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 146305642 Common - protein of unknown function DUF1249 Pmen_0607 27 COG3151 COG3151, Uncharacterized protein conserved in bacteria Function unknown 146307468 Common - hypothetical protein Pmen_2445 3 COG3728 XtmA, Phage terminase, small subunit DNA replication, recombination, and repair 146308300 Common - alpha/beta hydrolase fold Pmen_3280 83 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 146309385 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) Pmen_4371 176 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 146309049 Common - hypothetical protein Pmen_4035 4 None None None 146305282 Pathogen - protein of unknown function DUF1127 Pmen_0241 1 COG5457 COG5457, Uncharacterized conserved small protein Function unknown 146305507 Common - integral membrane protein, YccS/YhfK family Pmen_0470 35 COG1289 COG1289, Predicted membrane protein Function unknown 146309536 Common - hypothetical protein Pmen_4522 6 None None None 146308181 Common - Methyltransferase type 12 Pmen_3161 45 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 146307482 Common - alpha/beta hydrolase fold Pmen_2459 136 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 146306957 Common - type IV pilus assembly PilZ Pmen_1928 7 None None None 146308096 Common - integron integrase Pmen_3075 94 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 146308739 Common - HI0933 family protein Pmen_3724 82 COG2081 COG2081, Predicted flavoproteins General function prediction only 146306396 Common - ABC transporter related Pmen_1364 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 146307090 Common - putative signal transduction protein Pmen_2062 47 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 146309474 Common - Carbonic anhydrase/acetyltransferase isoleucine patch superfamily-like protein Pmen_4460 189 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 146308673 Common - regulatory protein, LuxR Pmen_3658 118 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 146309446 Common - NAD/NADP transhydrogenase alpha subunit-like protein Pmen_4432 117 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 146309204 Pathogen - hypothetical protein Pmen_4190 1 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 146307351 Pathogen - hypothetical protein Pmen_2326 1 None None None 146306934 Common - cell developmental protein SirA Pmen_1905 106 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 146307499 Common - two component transcriptional regulator, winged helix family Pmen_2476 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 146306738 Common - RNA-binding S4 domain protein Pmen_1707 132 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 146306542 Common - transcriptional regulator, LysR family Pmen_1510 175 COG0583 LysR, Transcriptional regulator Transcription 146306984 Common - pentapeptide repeat protein Pmen_1956 92 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 146306265 Common minE cell division topological specificity factor MinE Pmen_1233 84 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 146306885 Common rpsA 30S ribosomal protein S1 Pmen_1854 219 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 146307020 Common - hypothetical protein Pmen_1992 14 None None None 146307643 Common - Cyclohexanone monooxygenase Pmen_2620 75 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 146306479 Common - protein of unknown function DUF6, transmembrane Pmen_1447 34 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 146307603 Common - ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components-like protein Pmen_2580 82 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 146307667 Common recR recombination protein RecR Pmen_2645 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 146305709 Common - TRAP C4-dicarboxylate transport system permease DctM subunit Pmen_0674 122 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 146307287 Common - hypothetical protein Pmen_2262 18 None None None 146308146 Common - alpha/beta hydrolase fold Pmen_3126 164 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 146306179 Common - transcriptional regulator, LysR family Pmen_1145 99 COG0583 LysR, Transcriptional regulator Transcription 146306480 Common - GCN5-related N-acetyltransferase Pmen_1448 3 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 146309611 Common - response regulator receiver and ANTAR domain protein Pmen_4597 29 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 146307029 Common - transcriptional regulator, LysR family Pmen_2001 133 COG0583 LysR, Transcriptional regulator Transcription 146307731 Common - oxidoreductase Pmen_2709 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 146308101 Pathogen - hypothetical protein Pmen_3080 1 None None None 146306967 Common - hypothetical protein Pmen_1938 16 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 146305833 Common - transport system permease protein Pmen_0798 168 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 146308196 Common - NADP oxidoreductase, coenzyme F420-dependent Pmen_3176 60 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 146307015 Common - exodeoxyribonuclease V, alpha subunit Pmen_1987 119 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 146308172 Common - ribonucleotide-diphosphate reductase subunit beta Pmen_3152 154 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 146308147 Common - maltose/maltodextrin transporter ATP-binding protein Pmen_3127 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 146308348 Common - GCN5-related N-acetyltransferase Pmen_3328 94 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 146308014 Common - hypothetical protein Pmen_2992 4 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only