Saccharopolyspora erythraea NRRL 2338, complete genome NC_009142 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 134097676 Nonpathogen - hypothetical protein SACE_1080 1 None None None 134103023 Common trpS tryptophanyl-tRNA synthetase SACE_6592 229 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 134101927 Nonpathogen - hypothetical protein SACE_5428 1 None None None 134098915 Common - putative transposon tn5714 transposase SACE_2351 54 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134098831 Nonpathogen - hypothetical protein SACE_2262 1 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 134099909 Common - alkylated DNA repair protein SACE_3370 56 COG3145 AlkB, Alkylated DNA repair protein DNA replication, recombination, and repair 134101008 Common - multi-domain beta-ketoacyl synthase SACE_4475 210 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134099555 Common cysK3 putative cysteine synthase SACE_3013 219 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 134098932 Nonpathogen - transcriptional regulator, CdaR SACE_2368 7 None None None 134099514 Common - hypothetical protein SACE_2972 8 None None None 134100375 Common - cobalamin (vitamin B12) biosynthesis CbiM protein SACE_3840 65 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 134101018 Common blaB4 metallo-beta-lactamase SACE_4485 186 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 134100385 Common - protein of unknown function DUF6, transmembrane SACE_3850 49 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 134100179 Common matC dicarboxylate-carrier protein SACE_3641 18 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 134100054 Common catI 3-oxoadipate:succinyl-CoA transferase, A subunit SACE_3516 44 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 134101621 Common ISTB transposase SACE_5105 97 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 134099696 Nonpathogen - hypothetical protein SACE_3155 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 134101870 Common - pyridoxamine 5'-phosphate oxidase-related,FMN-binding protein SACE_5368 13 None None None 134102126 Common - pyruvate dehydrogenase (lipoamide) SACE_5676 154 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 134099293 Common - enoyl-CoA hydratase/isomerase-like protein SACE_2748 138 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 134102337 Nonpathogen - hypothetical protein SACE_5890 1 None None None 134098964 Common - putative signal-transduction protein with CBS domains SACE_2402 78 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 134098764 Common - putative peptide transport system permease SACE_2194 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 134100305 Common - Asp/Glu racemase SACE_3770 34 COG3473 COG3473, Maleate cis-trans isomerase Secondary metabolites biosynthesis, transport, and catabolism 134096804 Common ohrA organic hydroperoxide resistance protein SACE_0187 110 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 134099584 Common matC dicarboxylate carrier protein SACE_3042 15 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 134103213 Common hscA molecular chaperone SACE_6784 234 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 134102280 Common - hypothetical protein SACE_5832 52 COG1799 COG1799, Uncharacterized protein conserved in bacteria Function unknown 134100685 Common - peptidase S15 SACE_4152 69 COG2936 COG2936, Predicted acyl esterases General function prediction only 134102068 Common metF 5,10-methylenetetrahydrofolate reductase SACE_5618 48 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 134097212 Nonpathogen - hypothetical protein SACE_0602 1 None None None 134103091 Common - putative DNA-directed DNA polymerase SACE_6661 10 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 134099108 Nonpathogen - transposase, IS4 SACE_2553 16 COG5659 COG5659, FOG: Transposase DNA replication, recombination, and repair 134098890 Common tnpA Tn5045 transposase SACE_2326 36 None None None 134099238 Common - MbtH-like protein SACE_2692 36 COG3251 COG3251, Uncharacterized protein conserved in bacteria Function unknown 134102557 Common - hypothetical protein SACE_6120 5 None None None 134102159 Common - putative transcriptional regulator SACE_5710 169 COG0583 LysR, Transcriptional regulator Transcription 134100437 Common - AMP-dependent synthetase and ligase SACE_3902 219 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 134103055 Common sigC RNA polymerase sigma factor SACE_6625 160 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 134099135 Common - protein of unknown function DUF1362 SACE_2580 11 COG4288 COG4288, Uncharacterized protein conserved in bacteria Function unknown 134103039 Nonpathogen - hypothetical protein SACE_6609 1 None None None 134098835 Common - hypothetical protein SACE_2266 4 None None None 134098755 Common - putative deoxyguanosine triphosphate triphosphohydrolase SACE_2185 160 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 134098528 Common cvnA5 sensor-like histidine kinase SACE_1953 14 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 134099286 Common - hypothetical protein SACE_2741 16 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 134101977 Common - RNA polymerase, sigma-24 subunit, ECF subfamily SACE_5521 48 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 134098101 Common - carbon starvation protein CstA SACE_1515 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 134101628 Nonpathogen - hypothetical protein SACE_5116 1 None None None 134102154 Nonpathogen - hypothetical protein SACE_5705 1 None None None 134099817 Common - FMNH2-utilizing oxygenase SACE_3278 52 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 134102505 Common - transporter, solute:sodium symporter (SSS) family protein SACE_6068 45 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 134103299 Common rplK 50S ribosomal protein L11 SACE_6871 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 134098294 Nonpathogen - hypothetical protein SACE_1712 1 COG4767 VanZ, Glycopeptide antibiotics resistance protein Defense mechanisms 134100503 Common - probable NADPH-dependent fmn reductase oxidoreductase protein SACE_3968 53 COG0431 COG0431, Predicted flavoprotein General function prediction only 134103645 Common - sugar transporter, MFS superfamily SACE_7223 114 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134101887 Common - hypothetical protein SACE_5385 17 None None None 134103351 Common - cysteine synthase SACE_6924 199 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 134102180 Common - general substrate transporter SACE_5731 139 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 134098846 Common sacC,sacL levanase SACE_2277 53 COG1621 SacC, Beta-fructosidases (levanase/invertase) Carbohydrate transport and metabolism 134099779 Common - hypothetical protein SACE_3240 35 None None None 134101104 Common echA7 enoyl-CoA hydratase/isomerase family protein SACE_4571 148 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 134102048 Common - MazG nucleotide pyrophosphohydrolase domain protein SACE_5598 38 COG1694 MazG, Predicted pyrophosphatase General function prediction only 134102349 Common thyX FAD-dependent thymidylate synthase SACE_5902 58 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 134097923 Nonpathogen - hypothetical protein SACE_1336 1 None None None 134103402 Common - oxidoreductase, short-chain dehydrogenase/reductase family SACE_6976 225 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 134099112 Common - hydrolase SACE_2557 125 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134098058 Common - cobalamin (vitamin B12) biosynthesis CbiX protein SACE_1472 35 COG2138 COG2138, Uncharacterized conserved protein Function unknown 134097348 Nonpathogen - hypothetical protein SACE_0742 1 None None None 134099772 Common - inosine-uridine preferring nucleoside hydrolase SACE_3233 87 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 134096695 Common - ABC quaternary amine transporter, permease component SACE_0077 146 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 134103223 Nonpathogen engXCA endo-1,4-beta-glucanase SACE_6795 1 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 134102270 Nonpathogen - hypothetical protein SACE_5822 1 None None None 134103010 Common - putative sugar ABC transporter integral membrane protein SACE_6578 106 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 134102779 Common - patatin-like phospholipase SACE_6345 137 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 134096650 Common - hypothetical protein SACE_0032 8 COG3832 COG3832, Uncharacterized conserved protein Function unknown 134100037 Nonpathogen - hypothetical protein SACE_3499 1 None None None 134102567 Common ddl D-alanyl-alanine synthetase A SACE_6130 215 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 134096840 Nonpathogen - hypothetical protein SACE_0223 5 None None None 134100473 Common hpcE putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase SACE_3938 177 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 134102116 Common - iron ABC transporter, substrate binding protein SACE_5666 42 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 134102857 Common - acetyltransferase SACE_6423 85 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 134098939 Common acsA acetyl-CoA synthetase SACE_2375 216 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 134100871 Common - protein of unknown function DUF112,transmembrane SACE_4338 46 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 134098853 Common - FxsA cytoplasmic membrane protein SACE_2285 21 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 134098895 Common citE3 citrate lyase beta subunit SACE_2331 114 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 134098456 Common - glyoxalase/bleomycin resistance protein/dioxygenase SACE_1880 38 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 134098591 Common - SNO glutamine amidotransferase SACE_2017 86 COG0311 PDX2, Predicted glutamine amidotransferase involved in pyridoxine biosynthesis Coenzyme metabolism 134099785 Nonpathogen - hypothetical protein SACE_3246 1 None None None 134103683 Common - Cof-like hydrolase SACE_7261 91 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 134102179 Common - ATP-dependent DNA helicase SACE_5730 38 COG3973 COG3973, Superfamily I DNA and RNA helicases General function prediction only 134096829 Nonpathogen - hypothetical protein SACE_0212 2 None None None 134100576 Common fprD ferredoxin reductase SACE_4041 194 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 134101512 Nonpathogen - hypothetical protein SACE_4984 1 None None None 134098352 Common pepX x-prolyl-dipeptidyl aminopeptidase SACE_1771 44 COG2936 COG2936, Predicted acyl esterases General function prediction only 134100525 Common - beta-lactamase-like SACE_3990 122 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 134101328 Nonpathogen - hypothetical protein SACE_4799 1 None None None 134102342 Nonpathogen - hypothetical protein SACE_5895 1 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 134101849 Common - hypothetical protein SACE_5347 10 None None None 134096894 Common tdsD nitroreductase family protein SACE_0280 49 COG0778 NfnB, Nitroreductase Energy production and conversion 134099482 Common - hypothetical protein SACE_2940 124 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134098495 Common - oxidoreductase, Gfo/Idh/MocA family SACE_1920 173 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 134097600 Nonpathogen - hypothetical protein SACE_1004 1 None None None 134100439 Common yihR predicted aldose-1-epimerase SACE_3904 66 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 134102869 Common aroA 3-phosphoshikimate 1-carboxyvinyltransferase SACE_6435 229 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 134103672 Common - hypothetical protein SACE_7250 86 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 134102058 Common - IclR-family transcriptional regulator SACE_5608 122 COG1414 IclR, Transcriptional regulator Transcription 134102219 Common - putative RNA polymerase, sigma-24 subunit, ECF subfamily SACE_5770 41 COG4941 COG4941, Predicted RNA polymerase sigma factor containing a TPR repeat domain Transcription 134099763 Common - non-ribosomal peptide synthetase modules SACE_3224 219 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134097822 Common hpcE putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase SACE_1233 180 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 134099524 Nonpathogen - hypothetical protein SACE_2982 1 None None None 134098785 Common - probable magnesium chelatase subunit ChlI SACE_2215 70 COG1239 ChlI, Mg-chelatase subunit ChlI Coenzyme metabolism 134099693 Common - possible lipoate-protein ligase A SACE_3151 13 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 134096774 Common - hypothetical protein SACE_0157 53 COG0754 Gsp, Glutathionylspermidine synthase Amino acid transport and metabolism 134098117 Common - carboxypeptidase (secreted protein) SACE_1531 20 COG2866 COG2866, Predicted carboxypeptidase Amino acid transport and metabolism 134101316 Common - TetR-family transcriptional regulator SACE_4784 25 None None None 134101134 Common - oxidoreductase, short chain dehydrogenase/reductase family SACE_4601 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134100412 Common - beta-lactamase class A-like protein SACE_3877 47 COG2367 PenP, Beta-lactamase class A Defense mechanisms 134103608 Common - uncharacterized membrane-associated protein-like SACE_7186 167 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 134097668 Nonpathogen - hypothetical protein SACE_1072 1 None None None 134100978 Common - K+-dependent Na+/Ca+ exchanger related-protein SACE_4445 55 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 134101201 Common - short chain dehydrogenase SACE_4669 80 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134100148 Common - hypothetical protein SACE_3610 44 COG2320 GrpB, Uncharacterized conserved protein Function unknown 134101386 Common - probable multidrug ABC transporter, permease SACE_4856 10 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 134102169 Common pyk3 pyruvate kinase SACE_5720 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 134099761 Common - hypothetical protein SACE_3222 76 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 134103307 Common - lysophospholipase-like protein SACE_6879 9 COG2267 PldB, Lysophospholipase Lipid metabolism 134098799 Common - peptidase U34, dipeptidase SACE_2230 24 COG4690 PepD, Dipeptidase Amino acid transport and metabolism 134100369 Common pkn29 putative serine/threonine protein kinase SACE_3834 147 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 134097292 Common - NmrA-like SACE_0685 88 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 134103804 Common trxB thioredoxin reductase SACE_7384 245 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 134097465 Nonpathogen - hypothetical protein SACE_0862 1 None None None 134097217 Common - hypothetical protein SACE_0607 69 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 134101142 Common - probable transcriptional regulator, LysR family SACE_4609 185 COG0583 LysR, Transcriptional regulator Transcription 134096838 Nonpathogen - hypothetical protein SACE_0221 2 None None None 134101324 Nonpathogen - hypothetical protein SACE_4794 1 None None None 134099948 Common - AMP-dependent Acyl-CoA synthetase and ligase SACE_3409 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134098256 Common - ABC transporter substrate-binding protein SACE_1673 20 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 134101603 Nonpathogen - hypothetical protein SACE_5080 1 None None None 134101519 Common - IS21 family transposase SACE_4991 50 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 134097399 Common pabB para-aminobenzoate synthase component I SACE_0793 223 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 134100155 Nonpathogen - GCN5-related N-acetyltransferase SACE_3617 5 COG3153 COG3153, Predicted acetyltransferase General function prediction only 134100890 Common - transcriptional regulator, IclR family SACE_4357 119 COG1414 IclR, Transcriptional regulator Transcription 134102870 Common - GTPase EngC SACE_6436 162 COG1162 COG1162, Predicted GTPases General function prediction only 134097744 Common cvnD10 ATP/GTP binding protein SACE_1152 30 COG2229 COG2229, Predicted GTPase General function prediction only 134100502 Common - ABC transporter substrate-binding protein SACE_3967 148 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 134102469 Nonpathogen - hypothetical protein SACE_6031 1 None None None 134100135 Common - transcriptional regulator, XRE family SACE_3597 10 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 134100283 Common - hypothetical protein SACE_3748 22 COG0789 SoxR, Predicted transcriptional regulators Transcription 134101598 Nonpathogen - hypothetical protein SACE_5075 1 None None None 134099408 Common gdmRII LuxR-family transcriptional regulator SACE_2866 30 COG3899 COG3899, Predicted ATPase General function prediction only 134098335 Common dapF diaminopimelate epimerase SACE_1753 203 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 134101637 Common - ATP/GTP binding protein SACE_5127 27 None None None 134100819 Common - thioesterase SACE_4286 50 COG3208 GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 134096700 Nonpathogen - hypothetical protein SACE_0082 1 COG4767 VanZ, Glycopeptide antibiotics resistance protein Defense mechanisms 134100992 Common - hypothetical protein SACE_4459 5 None None None 134098418 Common - acetyltransferase SACE_1842 10 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 134100899 Common - hypothetical protein SACE_4366 9 None None None 134100868 Common speD S-adenosylmethionine decarboxylase proenzyme SACE_4335 66 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 134101243 Common abgT predicted cryptic aminobenzoyl-glutamate transporter SACE_4711 38 COG2978 AbgT, Putative p-aminobenzoyl-glutamate transporter Coenzyme metabolism 134101461 Nonpathogen - hypothetical protein SACE_4931 1 None None None 134097227 Common - DsbA-like thioredoxin domain protein SACE_0617 85 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 134099395 Common caiD carnitinyl-CoA dehydratase SACE_2852 175 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 134099517 Common iorB isoquinoline 1-oxidoreductase, beta subunit SACE_2975 71 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 134102025 Common - carbamoyltransferase SACE_5575 52 COG2192 COG2192, Predicted carbamoyl transferase, NodU family Posttranslational modification, protein turnover, chaperones 134103797 Common pcnA poly(A) polymerase SACE_7377 214 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 134102388 Common - RIO-type serine/threonine protein kinase SACE_5941 65 COG1718 RIO1, Serine/threonine protein kinase involved in cell cycle control Signal transduction mechanisms / Cell division and chromosome partitioning 134102545 Common - ATP-dependent helicase SACE_6108 36 COG3973 COG3973, Superfamily I DNA and RNA helicases General function prediction only 134102921 Common - hypothetical protein SACE_6488 99 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 134097559 Common CalU12 CalU12 SACE_0962 25 COG4312 COG4312, Uncharacterized protein conserved in bacteria Function unknown 134097181 Common - ABC transporter substrate-binding protein SACE_0571 119 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 134102964 Common eryA putative erythritol kinase protein SACE_6531 184 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 134098410 Common - two-component system response regulator SACE_1833 168 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134100276 Common - L-carnitine dehydratase/bile acid-inducible protein F SACE_3741 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 134102766 Common - secreted protease SACE_6331 35 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134102753 Common agaY tagatose-bisphosphate aldolase SACE_6318 176 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 134097730 Nonpathogen - hypothetical protein SACE_1135 1 None None None 134102628 Common - hypothetical protein SACE_6191 65 COG3176 COG3176, Putative hemolysin General function prediction only 134101248 Common - SAM-dependent methyltransferase SACE_4716 78 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134102324 Nonpathogen - possible conserved transmembrane alanine rich protein SACE_5877 2 None None None 134096854 Common - glycerophosphoryl diester phosphodiesterase SACE_0237 126 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 134097962 Common cypA cytochrome P450 SACE_1376 75 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134101338 Nonpathogen - hypothetical protein SACE_4809 2 None None None 134099508 Common - metabolite transporter, MFS superfamily SACE_2966 128 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 134102955 Nonpathogen - hypothetical protein SACE_6522 1 None None None 134102819 Common kgd alpha-ketoglutarate decarboxylase SACE_6385 192 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 134097240 Common serC phosphoserine aminotransferase SACE_0630 162 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 134103004 Common ssfR IclR-family transcriptional regulator SACE_6572 102 COG1414 IclR, Transcriptional regulator Transcription 134100695 Common - ABC sugar transporter, substrate-binding component SACE_4162 87 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 134101344 Nonpathogen - hypothetical protein SACE_4815 1 None None None 134102725 Common - SUA5/YciO/YrdC/YwlC SACE_6289 233 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 134099924 Common clpA clp protease ATP binding subunit SACE_3385 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 134099810 Common crtU beta-carotene desaturase/methylase SACE_3271 15 COG3349 COG3349, Uncharacterized conserved protein Function unknown 134102189 Nonpathogen - hypothetical protein SACE_5740 1 None None None 134098905 Common - oxidoreductase short-chain dehydrogenase/reductase family SACE_2341 216 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 134100519 Common - probable adenylate cyclase SACE_3984 31 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 134097337 Common eryBIII eryBIII NDP-4-keto-2,6-dideoxyhexose 3-C-methyltransferase SACE_0731 39 None None None 134098843 Common fruA putative fructose-specific permease SACE_2274 70 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 134100810 Common - probable ABC transporter, ATP-binding component SACE_4277 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 134102531 Common phoR phoR-putative two-component system sensor kinase SACE_6094 192 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 134098880 Common - RNA-directed DNA polymerase SACE_2315 85 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 134097697 Common - hypothetical protein SACE_1101 9 None None None 134099894 Common - hypothetical protein SACE_3355 6 None None None 134098007 Nonpathogen - hypothetical protein SACE_1421 1 None None None 134099474 Common - hypothetical protein SACE_2932 3 None None None 134101301 Nonpathogen - hypothetical protein SACE_4769 1 None None None 134098954 Common lldD1 L-Lactate dehydrogenase (cytochrome) SACE_2390 113 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 134102390 Common - nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase SACE_5943 8 COG3871 COG3871, Uncharacterized stress protein (general stress protein 26) General function prediction only 134098518 Common - hypothetical protein SACE_1943 56 COG3542 COG3542, Uncharacterized conserved protein Function unknown 134101658 Common - GntR-family transcriptional regulator SACE_5149 104 COG2186 FadR, Transcriptional regulators Transcription 134099054 Nonpathogen - hypothetical protein SACE_2497 1 None None None 134100921 Common - hypothetical protein SACE_4388 58 COG2187 COG2187, Uncharacterized protein conserved in bacteria Function unknown 134102269 Common - haloalkane dehalogenase SACE_5821 144 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134101308 Common - sigma factor, sigma 70 type, group 4 (ECF) SACE_4776 44 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 134103579 Common - putative ABC transporter ATP-binding protein SACE_7157 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 134103487 Common - two component system sensor kinase SACE_7062 48 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 134101549 Common - acyl-CoA dehydrogenase SACE_5025 158 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134099885 Common - oxidoreductase, molybdopterin binding SACE_3346 110 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 134101899 Common - integral membrane protein TerC SACE_5397 91 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 134102796 Common fadB putative 3-hydroxyacyl-CoA dehydrogenase SACE_6362 161 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 134103721 Common - hypthetical protein SACE_7299 7 None None None 134100607 Common tnp transposase, ISlxx5 SACE_4072 63 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 134101976 Common - transcriptional regulator, LuxR family SACE_5520 73 COG3899 COG3899, Predicted ATPase General function prediction only 134096625 Common - hypothetical protein SACE_0006 18 COG5512 COG5512, Zn-ribbon-containing, possibly RNA-binding protein and truncated derivatives General function prediction only 134096624 Common recF recombination protein F SACE_0005 156 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 134097506 Common - putative conserved membrane protein SACE_0908 5 None None None 134099386 Common - putative zinc-binding oxidoreductase SACE_2843 3 COG2130 COG2130, Putative NADP-dependent oxidoreductases General function prediction only 134100219 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase SACE_3681 234 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134100809 Common - ABC transporter, permease component SACE_4276 121 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 134098662 Common - putative serine/threonine protein kinase SACE_2091 160 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 134100653 Common - hypothetical protein SACE_4119 15 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 134103690 Common - dynamin SACE_7268 23 COG1160 COG1160, Predicted GTPases General function prediction only 134103241 Common secY preprotein translocase subunit SecY SACE_6813 232 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 134098378 Common - hypothetical protein SACE_1798 4 None None None 134100100 Common - formate dehydrogenase alpha subunit SACE_3562 171 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 134100873 Nonpathogen - major facilitator superfamily MFS_1 SACE_4340 6 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134102918 Common purE phosphoribosylaminoimidazole carboxylase catalytic subunit SACE_6485 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 134101855 Common aldC aldehyde dehydrogenase family protein SACE_5353 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 134100727 Common - anti-sigma-factor antagonist SACE_4194 37 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 134099858 Common - luciferase-like monooxygenase SACE_3319 93 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 134102393 Common - putative 3-oxoacyl-ACP synthase SACE_5946 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134099759 Common - voltage-gated sodium channel SACE_3220 26 None None None 134097827 Nonpathogen - hypothetical protein SACE_1238 1 None None None 134103809 Common ddlA D-alanine--D-alanine ligase B SACE_7389 217 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 134097195 Common - hypothetical protein SACE_0585 18 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 134102747 Common - transcriptional regulator, XRE family with cupin sensor SACE_6312 97 COG1396 HipB, Predicted transcriptional regulators Transcription 134100643 Common - probable carboxyvinyl-carboxyphosphonate phosphorylmutase SACE_4109 114 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 134099064 Common csbX alpha-ketoglutarate permease SACE_2507 12 None None None 134103498 Nonpathogen - hypothetical protein SACE_7073 1 None None None 134097596 Common - hypothetical protein SACE_1000 5 None None None 134103495 Common - transcriptional regulator, XRE family SACE_7070 38 None None None 134103543 Common - hypothetical protein SACE_7121 5 None None None 134097569 Common - gas vesicle synthesis GvpLGvpF SACE_0973 20 None None None 134097957 Common - 6-phosphogluconate dehydrogenase, NAD-binding SACE_1371 163 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 134102419 Common - 2-dehydro-3-deoxyphosphogluconate aldolase / 4-hydroxy-2-oxoglutarate aldolase SACE_5973 118 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 134100441 Common - probable haloalkane dehalogenase SACE_3906 41 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134101600 Common - alternative 3-dehydroquinate synthase SACE_5077 28 COG1465 COG1465, Predicted alternative 3-dehydroquinate synthase Amino acid transport and metabolism 134098750 Common add adenosine deaminase SACE_2180 105 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 134103192 Common - putative ATP/GTP binding protein SACE_6762 140 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 134098347 Nonpathogen - hypothetical protein SACE_1766 1 None None None 134100724 Common - sensor kinase, two-component system SACE_4191 37 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 134102811 Common sdaA L-serine dehydratase SACE_6377 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 134100095 Common - hypothetical protein SACE_3557 19 COG5516 COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding General function prediction only 134099963 Common - hypothetical protein SACE_3424 17 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 134100260 Common - bifunctional deaminase-reductase domain protein SACE_3725 29 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 134103236 Common infA translation initiation factor IF1 SACE_6808 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 134101069 Common - transcriptional regulator, LacI family SACE_4536 125 COG1609 PurR, Transcriptional regulators Transcription 134100957 Common - hypothetical protein SACE_4424 12 None None None 134101949 Common ansP,yncF L-asparagine permease SACE_5451 97 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 134096984 Nonpathogen - membrane spanning protein SACE_0371 1 None None None 134099820 Nonpathogen - hypothetical protein SACE_3281 1 None None None 134099807 Nonpathogen - hypothetical protein SACE_3268 1 None None None 134100796 Common glcF glycolate oxidase, iron-sulfur subunit SACE_4263 158 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 134101610 Common - ISPsy21, transposase orfB SACE_5089 69 None None None 134100068 Common - sulfate adenylyltransferase subunit 2 SACE_3530 128 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 134102145 Common - hypothetical protein SACE_5696 29 COG5441 COG5441, Uncharacterized conserved protein Function unknown 134097779 Common - hypothetical protein SACE_1189 7 COG1990 COG1990, Uncharacterized conserved protein Function unknown 134098945 Common - response regulator, two-component system SACE_2381 180 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134098572 Common - mandelate racemase/muconate lactonizing enzyme SACE_1998 96 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 134097722 Nonpathogen - hypothetical protein SACE_1127 1 None None None 134102004 Common - possible secreted protein SACE_5554 9 None None None 134099899 Common - arginase/agmatinase/formiminoglutamase SACE_3360 27 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 134098437 Common ligC ATP-dependent DNA ligase SACE_1861 85 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 134100789 Common - ABC sugar transporter, permease component SACE_4256 210 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 134100853 Nonpathogen - integral membrane protein SACE_4320 2 None None None 134098769 Common - hypothetical protein SACE_2199 9 None None None 134097487 Common - integral membrane protein SACE_0889 6 None None None 134098026 Common - protein of unknown function DUF81 SACE_1440 83 COG0730 COG0730, Predicted permeases General function prediction only 134096674 Common - putative ABC transporter ATP-binding protein SACE_0056 248 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 134102945 Nonpathogen - hypothetical protein SACE_6512 1 None None None 134097929 Common - deoxyribonuclease V SACE_1342 73 COG1515 Nfi, Deoxyinosine 3'endonuclease (endonuclease V) DNA replication, recombination, and repair 134100591 Common - amidohydrolase SACE_4056 38 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 134097285 Common - integral membrane protein SACE_0678 6 None None None 134099013 Common uspA3 universal stress protein family SACE_2451 103 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 134099664 Nonpathogen - hypothetical protein SACE_3122 1 None None None 134100985 Nonpathogen - hypothetical protein SACE_4452 1 None None None 134099173 Common - secreted esterase SACE_2625 16 COG5640 COG5640, Secreted trypsin-like serine protease Posttranslational modification, protein turnover, chaperones 134103300 Common nusG putative transcription antitermination regulator SACE_6872 215 COG0250 NusG, Transcription antiterminator Transcription 134098486 Common fadE7 glutaryl-CoA dehydrogenase SACE_1911 160 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134098266 Common - hypothetical protein SACE_1683 3 None None None 134100638 Common - short chain dehydrogenase SACE_4104 236 COG3347 COG3347, Uncharacterized conserved protein Function unknown 134102034 Common - hypothetical protein SACE_5584 10 None None None 134098078 Common recO DNA repair protein RecO SACE_1492 61 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 134101378 Common - putative non-ribosomal peptide synthetase SACE_4849 32 None None None 134096649 Common - hypothetical protein SACE_0031 9 None None None 134103255 Common rpsQ 30S ribosomal protein S17 SACE_6827 231 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 134102500 Common - cyanate MFS transporter SACE_6063 74 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 134099829 Common - taurine dioxygenase, TauD/TfdA family SACE_3290 48 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 134101834 Nonpathogen - hypothetical protein SACE_5331 1 None None None 134098391 Common - Trk system potassium uptake protein TrkA SACE_1812 128 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 134101415 Common - hypothetical protein SACE_4885 24 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 134097049 Common radA DNA repair protein RadA SACE_0436 213 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 134103373 Common hemA glutamyl-tRNA reductase SACE_6946 179 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 134098343 Common - hypothetical protein SACE_1761 5 None None None 134100534 Common - hypothetical protein SACE_3999 12 COG5650 COG5650, Predicted integral membrane protein Function unknown 134097350 Nonpathogen - hypothetical protein SACE_0744 1 None None None 134101983 Common - iterative type I polyketide synthase SACE_5532 209 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134098790 Common - hypothetical protein SACE_2221 6 None None None 134103093 Nonpathogen - hypothetical protein SACE_6663 1 None None None 134098051 Common - small multidrug resistance protein, SMR family SACE_1465 97 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 134101956 Nonpathogen - hypothetical protein SACE_5458 3 None None None 134101126 Common malF ABC transporter sugar permease SACE_4593 145 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 134101905 Common - LysR-family transcriptional regulator SACE_5404 176 COG0583 LysR, Transcriptional regulator Transcription 134098680 Common - hypothetical protein SACE_2110 19 COG1306 COG1306, Uncharacterized conserved protein Function unknown 134098693 Common ribA bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein SACE_2123 232 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 134103064 Nonpathogen - hypothetical protein SACE_6634 1 None None None 134099716 Common - undecaprenyl-phosphate galactose phosphotransferase SACE_3176 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 134100802 Common - ThiJ/PfpI SACE_4269 72 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 134096766 Common - DoxX SACE_0149 28 COG2259 COG2259, Predicted membrane protein Function unknown 134097528 Common fumC fumarate hydratase SACE_0930 230 COG0114 FumC, Fumarase Energy production and conversion 134098130 Common - secreted protein SACE_1544 7 None None None 134102876 Common secA1 preprotein translocase subunit SecA SACE_6442 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 134098425 Common - possible DNA ligase (ATP) SACE_1849 66 COG3285 COG3285, Predicted eukaryotic-type DNA primase DNA replication, recombination, and repair 134097598 Common trpS tryptophanyl tRNA synthetase SACE_1002 225 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 134101286 Common acoA acetoin dehydrogenase E1 component, alpha subunit SACE_4754 154 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 134097751 Nonpathogen - hypothetical protein SACE_1159 1 None None None 134100240 Common - glyoxalase/bleomycin resistance protein/dioxygenase SACE_3702 21 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 134102894 Common - hypothetical protein SACE_6461 18 None None None 134097140 Common - hypothetical protein SACE_0529 13 None None None 134101815 Common - TetR-family transcriptional regulator SACE_5312 38 None None None 134103073 Common - ABC phosphonate transporter, fused membrane subunits SACE_6643 98 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 134101175 Nonpathogen - hypothetical protein SACE_4642 3 None None None 134103273 Common - hypothetical protein SACE_6845 70 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 134096907 Common dnaK chaperone protein HscC SACE_0293 234 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 134097784 Common bioY biotin transporter protein SACE_1194 51 COG1268 BioY, Uncharacterized conserved protein General function prediction only 134101935 Common - glyoxalase/bleomycin resistance protein/dioxygenase SACE_5436 49 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 134103035 Common - two component system response regulator SACE_6605 205 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 134098036 Common - probable 2-nitropropane dioxygenase SACE_1450 102 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 134099144 Common - putative transposase SACE_2589 51 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 134101649 Common - carbon monoxide dehydrogenase large chain SACE_5140 106 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 134101673 Common - endoribonuclease L-PSP SACE_5165 84 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 134102601 Nonpathogen - hypothetical protein SACE_6164 1 None None None 134102305 Nonpathogen - hypothetical protein SACE_5857 1 None None None 134100160 Common - glycosyl hydrolase, family 15 SACE_3622 66 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 134099794 Common arsR regulatory protein, ArsR SACE_3255 149 COG0640 ArsR, Predicted transcriptional regulators Transcription 134097979 Nonpathogen - hypothetical protein SACE_1393 1 None None None 134097235 Common - drug resistance transporter, Bcr/CflA family SACE_0625 202 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134101795 Common gylR glycerol operon regulatory protein, IclR-family SACE_5292 112 COG1414 IclR, Transcriptional regulator Transcription 134101398 Common - transporter, MFS superfamily SACE_4868 26 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134102499 Common amt ammonium transporter SACE_6062 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 134103438 Common - hypothetical protein SACE_7013 4 None None None 134097766 Nonpathogen - PE-PGRS family protein SACE_1175 1 None None None 134102383 Common proS,pro prolyl-tRNA synthetase SACE_5936 244 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 134102855 Common thiJ 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis enzyme SACE_6421 115 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 134103114 Common - metabolite transporter, MFS superfamily SACE_6684 138 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 134099992 Common - histidine kinase/response regulator hybrid protein SACE_3454 187 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 134102604 Common - potassium/proton antiporter SACE_6167 140 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 134097711 Nonpathogen - hypothetical protein SACE_1116 1 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 134103265 Common rpsJ 30S ribosomal protein S10 SACE_6837 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 134098441 Nonpathogen - hypothetical protein SACE_1865 1 None None None 134097245 Common ureB urease beta subunit SACE_0635 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 134102835 Nonpathogen - hypothetical protein SACE_6401 3 None None None 134101840 Nonpathogen - small-conductance mechanosensitive channel protein SACE_5338 2 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 134102365 Common ribF riboflavin kinase / FMN adenylyltransferase SACE_5918 211 COG0196 RibF, FAD synthase Coenzyme metabolism 134096935 Nonpathogen - hypothetical protein SACE_0321 2 None None None 134099255 Common - putative oxidoreductase SACE_2710 10 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 134099627 Common fadE8 acyl-CoA dehydrogenase SACE_3085 143 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134097385 Common tnp transposase, ISlxx5 SACE_0779 63 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 134100775 Common - hypothetical protein SACE_4242 5 None None None 134098867 Common - hypothetical protein SACE_2301 110 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 134102802 Common - type I phosphodiesterase/nucleotide pyrophosphatase SACE_6368 25 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 134097264 Common - ABC transporter, ATP-binding component SACE_0655 249 COG4152 COG4152, ABC-type uncharacterized transport system, ATPase component General function prediction only 134096789 Common - hypothetical protein SACE_0172 4 None None None 134103700 Common - putative integral membrane transport protein SACE_7278 192 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 134100742 Common - transcriptional regulator, AraC family SACE_4209 134 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 134102202 Common trpE anthranilate synthase component I SACE_5753 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 134103621 Common clpB putative Clp protease ATP-binding subunit SACE_7199 230 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 134096971 Common - hypothetical protein SACE_0357 11 COG3832 COG3832, Uncharacterized conserved protein Function unknown 134099189 Common pncA pyrazinamidase / nicotinamidase SACE_2641 92 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 134099900 Common - glycerophosphoryl diester phosphodiesterase family SACE_3361 78 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 134097146 Common - xanthine dehydrogenase accessory factor SACE_0535 117 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 134097453 Common - oligopeptide ABC transporter ATP-binding protein SACE_0848 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 134101703 Common codA cytosine deaminase SACE_5196 67 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 134098288 Common - two component system response regulator SACE_1706 212 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134097605 Common - hypothetical protein SACE_1009 2 None None None 134103709 Nonpathogen - hypothetical protein SACE_7287 1 COG3021 COG3021, Uncharacterized protein conserved in bacteria Function unknown 134098535 Common - regulator SACE_1961 8 None None None 134102422 Common mtr mycothione/glutathione reductase SACE_5978 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 134102563 Common - proline/betaine transporter, MFS family SACE_6126 155 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134100348 Common - putative mutator MutT (7,8-dihydro-8-oxoguanine-triphosphatase) SACE_3813 96 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 134097794 Common - Mov34/MPN/PAD-1 SACE_1204 32 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 134101900 Common - putative ABC transporter ATP-binding protein SACE_5399 248 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 134099023 Common - phosphoribosyltransferase SACE_2461 68 COG1926 COG1926, Predicted phosphoribosyltransferases General function prediction only 134098123 Common galE UDP-glucose 4-epimerase SACE_1537 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 134102702 Common - putative ATP-binding component of ABC transporter SACE_6266 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 134097063 Common - hypothetical protein SACE_0450 5 None None None 134097653 Nonpathogen - hypothetical protein SACE_1057 1 None None None 134101560 Nonpathogen - hypothetical protein SACE_5036 5 None None None 134096747 Nonpathogen - hypothetical protein SACE_0129 1 None None None 134100341 Nonpathogen - hypothetical protein SACE_3806 1 None None None 134097071 Nonpathogen - hypothetical protein SACE_0458 2 None None None 134098953 Common pqqE coenzyme PQQ synthesis protein E SACE_2389 176 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 134100014 Common - hypothetical protein SACE_3476 7 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 134098402 Common - probable fatty acid oxidation complex alpha subunit SACE_1823 161 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 134102944 Nonpathogen - hypothetical protein SACE_6511 1 None None None 134103394 Common - osmotically inducible protein C, OsmC SACE_6968 71 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 134097738 Common - alpha/beta hydrolase fold SACE_1146 94 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134097078 Nonpathogen - hypothetical protein SACE_0465 1 None None None 134103632 Common dnaK 70 kD heat shock protein (molecular chaperone) SACE_7210 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 134099489 Common - TetR-family transcriptional regulator SACE_2947 37 COG1309 AcrR, Transcriptional regulator Transcription 134101239 Nonpathogen - hypothetical protein SACE_4707 1 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134097343 Nonpathogen - hypothetical protein SACE_0737 2 None None None 134098175 Common - 6-phospho-beta-glucosidase SACE_1589 52 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 134103711 Common - hypothetical protein SACE_7289 2 None None None 134101272 Nonpathogen - hypothetical protein SACE_4740 1 None None None 134102413 Common - secreted trypsin-like serine protease SACE_5967 23 COG5640 COG5640, Secreted trypsin-like serine protease Posttranslational modification, protein turnover, chaperones 134101750 Common - hypothetical protein SACE_5246 9 None None None 134102276 Common ileS isoleucyl-tRNA synthetase SACE_5828 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 134099374 Common - TRAP transporter solute receptor, TAXI family SACE_2831 87 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 134097313 Common - protease inhibitor protein SACE_0706 3 None None None 134098682 Common def peptide deformylase SACE_2112 211 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 134100560 Common amfT membrane translocator SACE_4025 115 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 134098461 Common - putative integral membrane protein SACE_1885 133 COG2860 COG2860, Predicted membrane protein Function unknown 134098578 Common thrS threonyl-tRNA synthetase SACE_2004 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 134103459 Nonpathogen - hypothetical protein SACE_7034 1 None None None 134097365 Common - bile acid:sodium symporter SACE_0759 55 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 134103741 Common groES2 putative GroES-family molecular chaperone SACE_7319 23 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 134101933 Common - hypothetical protein SACE_5434 4 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 134102356 Nonpathogen - hypothetical protein SACE_5909 1 None None None 134100317 Common - membrane protein implicated in regulation of membrane protease activity SACE_3782 21 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 134100571 Common pabAB putative para-aminobenzoic acid synthase SACE_4036 223 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 134100919 Common - hypothetical protein SACE_4386 9 None None None 134100187 Nonpathogen - hypothetical protein SACE_3649 1 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 134100227 Common - hypothetical protein SACE_3689 3 COG3963 COG3963, Phospholipid N-methyltransferase Lipid metabolism 134097374 Common - hypothetical protein SACE_0768 2 None None None 134100338 Common nirD nitrite reductase (NAD(P)H) small subunit SACE_3803 45 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 134099447 Common iolH myo-inositol catabolism protein SACE_2905 33 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 134100307 Common - putative D-isomer specific 2-hydroxyacid dehydrogenase SACE_3772 226 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 134098633 Nonpathogen - hypothetical protein SACE_2063 1 None None None 134097647 Common - magnesium and cobalt transport protein CorA SACE_1051 170 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 134098587 Common - possible DNA-binding protein SACE_2013 103 COG1396 HipB, Predicted transcriptional regulators Transcription 134098652 Common - integral membrane protein SACE_2081 10 None None None 134099003 Common acdA2 acyl-CoA synthetase (NDP forming type) SACE_2441 142 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 134101111 Common - probable transcriptional regulator SACE_4578 44 COG1309 AcrR, Transcriptional regulator Transcription 134098558 Nonpathogen - hypothetical protein SACE_1984 1 None None None 134101264 Common - regulatory protein SACE_4732 23 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 134103815 Common ytjA hypothetical protein SACE_7395 183 COG0759 COG0759, Uncharacterized conserved protein Function unknown 134098551 Common citM Mg++ citrate complex transporter SACE_1977 32 COG2851 CitM, H+/citrate symporter Energy production and conversion 134097786 Common dinG probable ATP-dependent DNA helicase-related protein SACE_1196 125 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 134101147 Nonpathogen - hypothetical protein SACE_4614 1 None None None 134097433 Nonpathogen - hypothetical protein SACE_0828 1 None None None 134101404 Common - carbon monoxide dehydrogenase medium subunit SACE_4874 81 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 134100581 Common - hypothetical protein SACE_4046 11 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 134096868 Common - peptidase S9, prolyl oligopeptidase active site region SACE_0253 136 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 134101481 Common insI IS30 transposase SACE_4951 63 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 134099417 Common - modular polyketide synthase- SACE_2875 237 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134102089 Common mutB methylmalonyl-CoA mutase SACE_5639 110 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 134103452 Common - PAS:GGDEF SACE_7027 156 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 134096843 Nonpathogen - hypothetical protein SACE_0226 1 None None None 134099871 Nonpathogen - phosphoesterase, PA-phosphatase related SACE_3332 1 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 134100470 Common - hypothetical protein SACE_3935 13 COG3254 COG3254, Uncharacterized conserved protein Function unknown 134100518 Common - protein of unknown function DUF125,transmembrane SACE_3983 42 COG1814 COG1814, Uncharacterized membrane protein Function unknown 134103132 Common - two-component system response regulator SACE_6702 132 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134101542 Common prt1 extracellular metalloprotease SACE_5014 45 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 134097485 Nonpathogen - hypothetical protein SACE_0887 2 None None None 134098873 Nonpathogen - hypothetical protein SACE_2308 2 None None None 134097028 Common tnp transposase, ISlxx5 SACE_0415 63 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 134096651 Nonpathogen - hypothetical protein SACE_0033 1 None None None 134101331 Common - amidohydrolase 3 SACE_4802 35 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 134101084 Common - binding-protein-dependent transport systems membrane component SACE_4551 220 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 134103611 Common pyrE orotate phosphoribosyltransferase SACE_7189 110 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 134098165 Common - putative low molecular weight protein-tyrosine-phosphatase SACE_1579 135 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 134100762 Common - MmcQ-like protein SACE_4229 39 COG2315 MmcQ, Uncharacterized protein conserved in bacteria Function unknown 134100744 Common tetM tetracycline resistance protein SACE_4211 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 134101466 Common - probable 2-dehydro-3-deoxy-phosphogluconate aldolase SACE_4936 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 134098621 Nonpathogen - hypothetical protein SACE_2051 4 None None None 134100206 Common - two-component system sensor kinase SACE_3668 63 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 134103590 Common purD phosphoribosylamine--glycine ligase SACE_7168 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 134098075 Common - hypothetical protein SACE_1489 2 COG3115 ZipA, Cell division protein Cell division and chromosome partitioning 134100041 Common - hypothetical protein SACE_3503 15 None None None 134098169 Common - hypothetical protein SACE_1583 22 COG1579 COG1579, Zn-ribbon protein, possibly nucleic acid-binding General function prediction only 134099045 Common - probable conserved integral membrane protein SACE_2488 23 None None None 134097151 Nonpathogen - hypothetical protein SACE_0540 1 None None None 134098740 Common - putative ABC-2 type transport system permease protein SACE_2170 13 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 134102259 Common merR2 transcriptional regulator, MerR family SACE_5811 84 COG0789 SoxR, Predicted transcriptional regulators Transcription 134102841 Common hutH histidine ammonia-lyase SACE_6407 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 134101562 Common - 6-carboxyhexanoate-CoA ligase SACE_5038 141 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 134100346 Common acn aconitate hydratase SACE_3811 221 COG1048 AcnA, Aconitase A Energy production and conversion 134101865 Nonpathogen - hypothetical protein SACE_5363 1 None None None 134097666 Common moeB molybdopterin biosynthesis-like protein MoeZ SACE_1070 221 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 134098196 Common - anion transporter SACE_1612 125 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 134097857 Common - putative S-adenosylmethionine decarboxylase SACE_1268 109 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 134097792 Common - probable transcriptional regulatory protein SACE_1202 14 None None None 134098366 Common sigB RNA polymerase sigma factor SigB SACE_1786 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 134100821 Common - putative non-ribosomal peptide synthetase SACE_4288 220 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134102454 Common - betaine-aldehyde dehydrogenase SACE_6016 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 134099754 Common - hypothetical protein SACE_3215 73 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 134100522 Common - hypothetical protein SACE_3987 14 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134102192 Common - putative iron ABC transporter substrate-binding protein SACE_5743 107 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 134098104 Nonpathogen - hypothetical protein SACE_1518 1 None None None 134102236 Common - putative binding-protein-dependent integral membrane transport protein SACE_5788 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 134101698 Common - GntR-family transcriptional regulator SACE_5191 128 COG2188 PhnF, Transcriptional regulators Transcription 134101444 Nonpathogen - hypothetical protein SACE_4914 1 None None None 134097370 Common galT putative galactose-1-phosphate uridylyltransferase SACE_0764 78 COG1085 GalT, Galactose-1-phosphate uridylyltransferase Energy production and conversion 134099682 Common - hypothetical protein SACE_3140 24 None None None 134103764 Common - hypothetical protein SACE_7344 11 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 134099083 Common ureA urease beta/gamma subunit SACE_2527 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 134102991 Common upp uracil phosphoribosyltransferase SACE_6559 163 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 134097640 Common - probable transmembrane protein SACE_1044 19 None None None 134101826 Common - hypothetical protein SACE_5323 5 None None None 134103474 Common - acetyltransferase SACE_7049 71 COG3153 COG3153, Predicted acetyltransferase General function prediction only 134102399 Common cobH precorrin-8X methylmutase SACE_5952 119 COG2082 CobH, Precorrin isomerase Coenzyme metabolism 134103733 Nonpathogen - hypothetical protein SACE_7311 1 None None None 134097455 Common udgB uracil-DNA glycosylase SACE_0850 84 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 134100613 Common - hypothetical protein SACE_4078 20 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 134101743 Common scpA segregation and condensation protein A SACE_5239 99 COG1354 COG1354, Uncharacterized conserved protein Function unknown 134099366 Common - transcriptional regulator, IclR family SACE_2823 120 COG1414 IclR, Transcriptional regulator Transcription 134101456 Common - putative betaine aldehyde dehydrogenase oxidoreductase protein SACE_4926 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 134103521 Common - phosphate ABC transporter, permease protein SACE_7098 224 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 134103104 Common - O-methyltransferase-like protein SACE_6674 37 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 134097038 Common - endonuclease/exonuclease/phosphatase SACE_0425 17 COG3021 COG3021, Uncharacterized protein conserved in bacteria Function unknown 134099236 Common - probable multidrug resistance transporter, MFS superfamily SACE_2690 86 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134098642 Common - putative AraC-family transcriptional regulator SACE_2071a 123 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 134099564 Common - IS1647-like transposase SACE_3022 39 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134097169 Common cvnB7 hypothetical protein SACE_0558 19 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 134102081 Nonpathogen - hypothetical protein SACE_5631 1 None None None 134096966 Common murQ N-acetylmuramic acid-6-phosphate etherase SACE_0352 83 COG2103 COG2103, Predicted sugar phosphate isomerase General function prediction only 134103440 Nonpathogen - hypothetical protein SACE_7015 1 None None None 134101490 Common - IS630 family transposase SACE_4961 16 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 134103445 Nonpathogen - hypothetical protein SACE_7020 1 None None None 134103517 Common - transcriptional regulator, XRE family SACE_7094 31 COG1396 HipB, Predicted transcriptional regulators Transcription 134098140 Nonpathogen - hypothetical protein SACE_1554 1 None None None 134102446 Nonpathogen - hypothetical protein SACE_6002 1 None None None 134101270 Common lysS lysyl-tRNA synthetase SACE_4738 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 134099379 Common lexA putative repressor of the SOS regulon SACE_2836 173 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 134102063 Common soxD sarcosine oxidase, delta chain SACE_5613 33 COG4311 SoxD, Sarcosine oxidase delta subunit Amino acid transport and metabolism 134097919 Common - MscS mechanosensitive ion channel SACE_1332 107 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 134101062 Common - hypothetical protein SACE_4529 25 COG3535 COG3535, Uncharacterized conserved protein Function unknown 134098319 Common - regulatory protein RecX SACE_1737 21 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 134100631 Common phrB putative deoxyribodipyrimidine photolyase SACE_4097 137 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 134103160 Common - 2-hydroxy-3-oxopropionate reductase SACE_6730 194 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 134097909 Common - single-strand binding protein SACE_1322 38 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 134097012 Common folX dihydroneopterin aldolase SACE_0399 59 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 134099158 Common tpase1 transposase SACE_2604 98 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 134100255 Nonpathogen - hypothetical protein SACE_3719 1 None None None 134102885 Nonpathogen - integral membrane protein SACE_6451 3 None None None 134099424 Common - possible transcriptional regulator, ArsR family SACE_2882 142 COG1733 COG1733, Predicted transcriptional regulators Transcription 134098480 Common - alcohol dehydrogenase, zinc-binding domain protein SACE_1905 148 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 134097053 Common ispF 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase SACE_0440 163 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 134100945 Common - mandelate racemase/muconate lactonizing enzyme SACE_4412 96 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 134101037 Common - secreted protein SACE_4504 15 None None None 134101392 Common - Na(+)-linked D-alanine glycine permease SACE_4862 113 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 134100205 Common - hypothetical protein SACE_3667 4 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 134099637 Common - glutamine synthetase (glutamate--ammonia ligase) SACE_3095 220 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 134101064 Common - transcriptional repressor SmtB SACE_4531 92 COG0640 ArsR, Predicted transcriptional regulators Transcription 134101474 Nonpathogen - hypothetical protein SACE_4944 1 None None None 134098081 Common - hypothetical protein SACE_1495 4 None None None 134099164 Common iscS cysteine desulfurase SACE_2615 237 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 134101921 Common - hypothetical protein SACE_5422 8 None None None 134101666 Common dapAch1 dihydrodipicolinate synthase protein SACE_5158 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 134097269 Common - FAD linked oxidase-like SACE_0660 166 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 134097931 Common - PE-PGRS family protein SACE_1344 37 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 134097995 Common - transcriptional regulator, TetR/AcrR family SACE_1409 61 COG1309 AcrR, Transcriptional regulator Transcription 134102666 Common - ribose ABC transporter, permease protein SACE_6229 128 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 134100092 Common - short chain dehydrogenase SACE_3554 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 134103484 Common yesE,yeeL hypothetical protein SACE_7059 14 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 134100251 Common - hypothetical protein SACE_3715 11 None None None 134103187 Common - IclR-family transcriptional regulator SACE_6757 123 COG1414 IclR, Transcriptional regulator Transcription 134097129 Nonpathogen - hypothetical protein SACE_0518 1 None None None 134099215 Common - putative transport system permease protein SACE_2668 161 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 134100383 Common - AMP-dependent synthetase and ligase SACE_3848 219 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 134099200 Common - MerR-family transcriptional regulator SACE_2653 89 COG0789 SoxR, Predicted transcriptional regulators Transcription 134099999 Common - putative sugar transporter SACE_3461 182 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 134100497 Common - hypothetical protein SACE_3962 145 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 134102245 Common - beta-lactamase-like protein SACE_5797 107 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 134099328 Common - aldehyde dehydrogenase (NAD+) SACE_2783 167 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 134097618 Common - putative secreted esterase/lipase/thioesterase family protein SACE_1022 50 COG2936 COG2936, Predicted acyl esterases General function prediction only 134098601 Common apt adenine phosphoribosyltransferase SACE_2027 166 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 134102764 Nonpathogen - hypothetical protein SACE_6329 1 None None None 134099535 Common - puitative transferase SACE_2993 3 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 134099299 Common tnp9B transposase, IS4 family SACE_2754 23 None None None 134097494 Nonpathogen - hypothetical protein SACE_0896 1 None None None 134099642 Common - protein of unknown function DUF323 SACE_3100 115 COG1262 COG1262, Uncharacterized conserved protein Function unknown 134102730 Nonpathogen - hypothetical protein SACE_6294 1 None None None 134097810 Common - hypothetical protein SACE_1220 4 None None None 134103513 Common - possible transcriptional regulator, LytR family SACE_7090 62 COG1316 LytR, Transcriptional regulator Transcription 134101642 Common - similar to superfamily I DNA and RNA helicases and helicase subunits SACE_5132 68 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 134100325 Common - putative Mg2+ transporter-C (MgtC) family protein SACE_3790 23 COG1285 SapB, Uncharacterized membrane protein Function unknown 134097361 Common - cobalamin synthesis CobW-like protein SACE_0755 61 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 134097201 Common - ribonucleotide-diphosphate reductase subunit beta SACE_0591 24 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 134097467 Nonpathogen - hypothetical protein SACE_0865 1 None None None 134101806 Common - secreted protein SACE_5303 66 COG2706 COG2706, 3-carboxymuconate cyclase Carbohydrate transport and metabolism 134101256 Common - hypothetical protein SACE_4724 13 COG3162 COG3162, Predicted membrane protein Function unknown 134102041 Nonpathogen - hypothetical protein SACE_5591 1 None None None 134099103 Common dapA2 dihydrodipicolinate synthase SACE_2548 202 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 134100235 Common - glyoxalase/bleomycin resistance protein/dioxygenase SACE_3697 41 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 134101569 Common prpD2 2-methylcitrate dehydratase SACE_5045 59 COG2079 PrpD, Uncharacterized protein involved in propionate catabolism General function prediction only 134099341 Common - transcriptional regulator, MarR family SACE_2796 33 COG1846 MarR, Transcriptional regulators Transcription 134102633 Common fixB electron transfer flavoprotein, alpha subunit SACE_6196 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 134103595 Common purA adenylosuccinate synthetase SACE_7173 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 134097476 Nonpathogen - hypothetical protein SACE_0876 1 None None None 134101676 Common fadE10 acyl-CoA dehydrogenase SACE_5168 164 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134101718 Common - phenylacetic acid degradation-like protein SACE_5213 20 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 134100783 Nonpathogen - hypothetical protein SACE_4250 2 None None None 134098270 Common qcrB cytochrome b, membrane protein SACE_1687 148 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 134101425 Common - putative secreted protein SACE_4895 7 None None None 134103173 Nonpathogen - hypothetical protein SACE_6743 1 None None None 134097122 Common thiC thiamine biosynthesis protein ThiC SACE_0511 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 134098188 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase SACE_1604 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 134098469 Common - hypothetical protein SACE_1893 16 COG3934 COG3934, Endo-beta-mannanase Carbohydrate transport and metabolism 134101699 Common iolE phosphate isomerases/epimerase SACE_5192 58 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 134099981 Common - transcriptional regulator (TetR/AcrR family) SACE_3443 104 COG1309 AcrR, Transcriptional regulator Transcription 134101473 Nonpathogen - hypothetical protein SACE_4943 2 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 134101168 Common - ABC transporter ATP-binding protein SACE_4635 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 134101774 Common - hypothetical protein SACE_5271 6 COG3934 COG3934, Endo-beta-mannanase Carbohydrate transport and metabolism 134102739 Common - obalt-zinc-cadmium resistance protein SACE_6303 193 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 134102377 Common - hypothetical protein SACE_5930 7 None None None 134097615 Common - membrane protease subunit, stomatin/prohibitin homolog SACE_1019 198 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 134103417 Common - hypothetical protein SACE_6991 13 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 134097582 Nonpathogen - PE-PGRS family protein SACE_0986 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 134102095 Common - excisionase/Xis, DNA-binding SACE_5645 6 COG2452 COG2452, Predicted site-specific integrase-resolvase DNA replication, recombination, and repair 134097427 Common pobA 4-hydroxybenzoate 3-monooxygenase SACE_0822 75 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 134100106 Common - putative ABC-transporter ATP-binding protein SACE_3568 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 134098211 Nonpathogen - hypothetical protein SACE_1628 1 None None None 134102139 Common - NAD-dependent epimerase/dehydratase SACE_5690 63 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 134102297 Common ftsQ cell division protein SACE_5849 37 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 134097560 Common - hypothetical protein SACE_0963 63 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 134103331 Common - electron transfer oxidoreductase SACE_6903 141 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 134099972 Common - pyridine nucleotide-disulphide oxidoreductase family protein SACE_3433 240 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 134098887 Common - hypothetical protein SACE_2323 10 COG3655 COG3655, Predicted transcriptional regulator Transcription 134099167 Common - amino acid adenylation SACE_2618 44 COG3319 COG3319, Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases Secondary metabolites biosynthesis, transport, and catabolism 134101322 Common - two-component system sensor kinase SACE_4790 221 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 134102809 Common - protein of unknown function DUF202 SACE_6375 19 COG2149 COG2149, Predicted membrane protein Function unknown 134098206 Common - glutamine synthetase SACE_1623 224 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 134101391 Common - putative transposase SACE_4861 51 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 134097723 Nonpathogen - hypothetical protein SACE_1128 1 None None None 134102912 Common rfbD dTDP-4-dehydrorhamnose reductase SACE_6479 160 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 134103112 Nonpathogen - DedA-like protein SACE_6682 2 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 134102820 Nonpathogen - hypothetical protein SACE_6386 1 None None None 134101196 Common - transcriptional regulator, LacI family SACE_4663 123 COG1609 PurR, Transcriptional regulators Transcription 134103321 Common nuoJ NADH dehydrogenase subunit J SACE_6893 33 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 134102077 Nonpathogen - hypothetical protein SACE_5627 2 None None None 134103790 Common - hypothetical protein SACE_7370 31 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 134101550 Common - long-chain-fatty-acid--CoA ligase, putative SACE_5026 218 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134101203 Common - purine catabolism PurC-like protein SACE_4671 18 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 134102976 Common - putative cation antiporter NADH dehydrogenase subunit SACE_6544 71 COG2111 MnhB, Multisubunit Na+/H+ antiporter, MnhB subunit Inorganic ion transport and metabolism 134100918 Common - HAD-superfamily hydrolase subfamily IA, variant 3 SACE_4385 137 COG0546 Gph, Predicted phosphatases General function prediction only 134097709 Common - UvrD/REP helicase SACE_1114 23 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 134099980 Common - DeoR-family transcriptional regulator SACE_3442 57 COG2378 COG2378, Predicted transcriptional regulator Transcription 134102677 Common - hypothetical protein SACE_6240 4 None None None 134096710 Common - short-chain dehydrogenase/reductase SDR SACE_0092 234 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134097130 Common - cell division control protein 48 (cdc48), AAA family SACE_0519 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 134097538 Nonpathogen - hypothetical protein SACE_0940 1 None None None 134102256 Nonpathogen - hypothetical protein SACE_5808 2 None None None 134096797 Common - glycosyl transferase, group 2 family protein SACE_0180 175 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 134101318 Common - putative secreted protein SACE_4786 17 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 134102585 Common gltX glutamyl-tRNA synthetase SACE_6148 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 134097158 Nonpathogen - hypothetical protein SACE_0547 1 None None None 134101439 Common - dimethylallyltranstransferase / geranyltranstransferase / geranylgeranyl pyrophosphate synthetase SACE_4909 241 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 134097900 Common - hypothetical protein SACE_1313 56 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 134102017 Common - transferase SACE_5567 36 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 134102930 Common - MaoC-like dehydratase SACE_6497 56 COG2030 MaoC, Acyl dehydratase Lipid metabolism 134099300 Common - IS1647-like transposase SACE_2755 39 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134101957 Common - hypothetical protein SACE_5459 19 COG3115 ZipA, Cell division protein Cell division and chromosome partitioning 134102164 Nonpathogen - hypothetical protein SACE_5715 1 None None None 134099128 Common - hypothetical protein SACE_2573 9 None None None 134099261 Nonpathogen - hypothetical protein SACE_2716 1 None None None 134102403 Common - uroporphyrin-III C-methyltransferase SACE_5957 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 134098506 Common - amidate substrates transporter protein SACE_1931 17 None None None 134101639 Common pglY bacteriophage (phiC31) resistance gene PglY SACE_5129 9 None None None 134101885 Common fadE21 putative acyl-CoA dehydrogenase SACE_5383 103 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134101950 Common bglB2 beta-glucosidase SACE_5452 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 134102774 Common - trypsin-like serine protease SACE_6340 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 134099287 Common - putative lipid-transfer protein SACE_2742 93 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 134099834 Common - alpha/beta hydrolase SACE_3295 23 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 134100967 Common - taurine transport system permease protein TauC SACE_4434 190 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 134101966 Nonpathogen - hypothetical protein SACE_5510 1 None None None 134103342 Nonpathogen - hypothetical protein SACE_6915 2 None None None 134099397 Nonpathogen - hypothetical protein SACE_2854 1 None None None 134098509 Common - putative RNA polymerase sigma factor SACE_1934 65 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 134100022 Common ureA urease beta/gamma subunit SACE_3484 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 134100454 Common - hypothetical protein SACE_3919 39 COG3919 COG3919, Predicted ATP-grasp enzyme General function prediction only 134101048 Common - hypothetical protein SACE_4515 2 None None None 134099504 Common - sodium:proline symporter SACE_2962 153 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 134097171 Common cvnD6 ATP/GTP-binding protein SACE_0560 30 COG2229 COG2229, Predicted GTPase General function prediction only 134099015 Common - hypothetical protein SACE_2453 56 COG2187 COG2187, Uncharacterized protein conserved in bacteria Function unknown 134099610 Nonpathogen - hypothetical protein SACE_3068 1 None None None 134097162 Common mdlC benzoylformate decarboxylase SACE_0551 217 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 134098292 Common - putative serine/threonine protein kinase SACE_1710 155 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 134103155 Common - peptidase M22, glycoprotease SACE_6725 177 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 134096717 Common - integral membrane transporter SACE_0099 32 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 134100419 Common - probable pyruvate dehydrogenase (acetyl-transferring) beta subunit SACE_3884 165 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 134101251 Common - hypothetical protein SACE_4719 15 COG4954 COG4954, Uncharacterized protein conserved in bacteria Function unknown 134101299 Common - short-chain dehydrogenase/reductase SDR SACE_4767 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134100359 Common cbiN hypothetical protein SACE_3824 38 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 134103502 Nonpathogen - hypothetical protein SACE_7077 2 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 134100224 Common pecS transcriptional regulator, MarR family SACE_3686 58 COG1846 MarR, Transcriptional regulators Transcription 134099616 Common - hydrogenase expression/formation protein HypE SACE_3074 142 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 134100557 Common - AMP-dependent synthetase and ligase SACE_4022 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134097085 Nonpathogen - hypothetical protein SACE_0471 1 None None None 134096873 Common - oligopeptide/dipeptide ABC transporter, permease protein SACE_0258 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 134099519 Common - transcriptional regulator, BadM/Rrf2 family SACE_2977 101 COG1959 COG1959, Predicted transcriptional regulator Transcription 134101626 Nonpathogen - hypothetical protein SACE_5112 6 COG1353 COG1353, Predicted hydrolase of the HD superfamily (permuted catalytic motifs) General function prediction only 134101488 Nonpathogen - lanthionine synthetase C-like SACE_4959 6 COG4403 LcnDR2, Lantibiotic modifying enzyme Defense mechanisms 134101078 Common - transcriptional regulator SACE_4545 89 COG1846 MarR, Transcriptional regulators Transcription 134099718 Nonpathogen - hypothetical protein SACE_3178 1 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 134100081 Common - bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase SACE_3543 219 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 134098316 Common - hypothetical protein SACE_1734 14 None None None 134100926 Nonpathogen - hypothetical protein SACE_4393 1 None None None 134098153 Common - hypothetical protein SACE_1567 12 None None None 134097306 Common - 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase SACE_0699 74 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 134098770 Common - alpha/beta hydrolase fold SACE_2200 167 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134096913 Nonpathogen - hypothetical protein SACE_0299 1 None None None 134101432 Common - probable oxidoreductase protein SACE_4902 9 None None None 134098708 Common uvrC nuclease subunit of the excinuclease ABC complex SACE_2138 224 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 134099880 Common - glycosyl transferase, family 2 SACE_3341 132 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 134102711 Common - transcriptional regulatory protein PadR- SACE_6275 16 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 134099315 Common - response regulator receiver and ANTAR domain protein SACE_2770 17 COG2203 FhlA, FOG: GAF domain Signal transduction mechanisms 134097694 Common - similar to metal-dependent hydrolase SACE_1098 90 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 134103037 Common - transcriptional regulator, XRE family SACE_6607 6 None None None 134101161 Common - hypothetical protein SACE_4628 6 None None None 134100988 Common - putative peptidase, M38 family SACE_4455 93 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 134100428 Common - integral membrane protein SACE_3893 47 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 134101584 Common - C4-dicarboxylate transport system (permease small protein) SACE_5060 27 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 134099741 Nonpathogen - hypothetical protein SACE_3202 1 None None None 134103296 Common rplJ 50S ribosomal protein L10 SACE_6868 205 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 134103204 Nonpathogen - hypothetical protein SACE_6775 1 None None None 134103243 Nonpathogen - hypothetical protein SACE_6815 1 None None None 134097910 Common - putative ABC transporter ATP-binding protein SACE_1323 247 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 134102435 Common - acetyltransferase, GNAT family SACE_5991 15 COG3393 COG3393, Predicted acetyltransferase General function prediction only 134103751 Nonpathogen - hypothetical protein SACE_7331 1 None None None 134097144 Common - ATPase associated with various cellular activities, AAA_5 SACE_0533 100 COG0714 COG0714, MoxR-like ATPases General function prediction only 134097272 Common - protein of unknown function DUF81 SACE_0663 13 None None None 134097515 Nonpathogen - hypothetical protein SACE_0917 1 None None None 134096813 Common - GtrA-like protein SACE_0196 6 COG2246 COG2246, Predicted membrane protein Function unknown 134098727 Common zwf,zwf2 glucose-6-phosphate 1-dehydrogenase SACE_2157 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 134100905 Nonpathogen - hypothetical protein SACE_4372 1 None None None 134101214 Common - transcriptional regulator, TetR family SACE_4682 28 COG1309 AcrR, Transcriptional regulator Transcription 134096740 Nonpathogen - hypothetical protein SACE_0122 1 None None None 134098198 Common - hypothetical protein SACE_1614 13 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 134102524 Common kdpC potassium-transporting ATPase C chain SACE_6087 93 COG2156 KdpC, K+-transporting ATPase, c chain Inorganic ion transport and metabolism 134096991 Nonpathogen - hypothetical protein SACE_0378 1 None None None 134101879 Common - hypothetical protein SACE_5377 57 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 134097182 Common - ABC transporter, putative molybdenum transport system SACE_0572 169 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 134098922 Common - secreted protein SACE_2358 10 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 134099920 Common uspA3 universal stress protein family SACE_3381 10 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 134100537 Common wrbA trp repressor binding protein SACE_4002 101 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 134098983 Common - stress-inducible protein SACE_2421 94 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 134099096 Common - hypothetical protein SACE_2541 3 None None None 134100776 Common pteC cytochrome P450 hydroxylase SACE_4243 70 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134099654 Common - hypothetical protein SACE_3112 5 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 134100713 Common - hypothetical protein SACE_4180 15 COG0439 AccC, Biotin carboxylase Lipid metabolism 134100752 Common - transcriptional regulator, MarR family SACE_4219 6 COG1846 MarR, Transcriptional regulators Transcription 134103537 Common - hypothetical protein SACE_7114 27 COG3246 COG3246, Uncharacterized conserved protein Function unknown 134101784 Common infC translation initiation factor IF3 protein SACE_5281 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 134099726 Nonpathogen - hypothetical protein SACE_3186 1 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 134101016 Nonpathogen - hypothetical protein SACE_4483 1 None None None 134103302 Common aspC aspartate aminotransferase SACE_6874 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 134097250 Common - putative integral membrane protein SACE_0640 27 COG3548 COG3548, Predicted integral membrane protein Function unknown 134099738 Nonpathogen - hypothetical protein SACE_3199 3 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 134103679 Nonpathogen - hypothetical protein SACE_7257 1 None None None 134096957 Common - aldehyde dehydrogenase (NAD+) SACE_0343 108 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 134097116 Common thiE thiamine-phosphate pyrophosphorylase SACE_0505 122 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 134101759 Common alkA DNA-3-methyladenine glycosylase II SACE_5255 81 COG2094 Mpg, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 134100174 Common - probable thioredoxin-disulfide reductase SACE_3636 69 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 134100665 Common - acyl carrier protein SACE_4132 193 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134103587 Common aspB aspartate aminotransferase SACE_7165 236 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 134097502 Common ilvA putative threonine dehydratase SACE_0904 221 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 134099674 Common abmC enoyl-CoA hydratase SACE_3132 179 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 134100088 Common - secreted protein SACE_3550 63 COG1273 COG1273, Uncharacterized conserved protein Function unknown 134097034 Common - putative transcriptional regulator SACE_0421 29 COG3903 COG3903, Predicted ATPase General function prediction only 134101890 Common lrp leucine responsive regulator SACE_5388 151 COG1522 Lrp, Transcriptional regulators Transcription 134100629 Common - hypothetical protein SACE_4095 175 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 134102441 Common hur hydroxyurea phosphotransferase SACE_5997 22 COG3570 StrB, Streptomycin 6-kinase Defense mechanisms 134098279 Common - cyclase/dehydrase SACE_1697 10 None None None 134099224 Nonpathogen - hypothetical protein SACE_2678 1 None None None 134098824 Nonpathogen - hypothetical protein SACE_2255 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 134098472 Common afsR regulatory protein SACE_1897 24 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 134099468 Common - putative Glycopeptide antibiotics resistance protein SACE_2926 7 COG4767 VanZ, Glycopeptide antibiotics resistance protein Defense mechanisms 134099390 Common - probable epoxide alpha/beta hydrolase SACE_2847 74 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134100622 Common - TRAP transporter solute receptor, TAXI family SACE_4087 58 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 134099819 Common - hypothetical protein SACE_3280 5 None None None 134098493 Common - two-component system sensor kinase SACE_1918 54 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 134098976 Common - heavy metal translocating P-type ATPase SACE_2414 231 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 134101227 Common - aldo/keto reductase SACE_4695 166 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 134099358 Common - phosphatidylethanolamine-binding protein SACE_2815 117 COG1881 COG1881, Phospholipid-binding protein General function prediction only 134103548 Nonpathogen - hypothetical protein SACE_7126 1 None None None 134100274 Common - carbonic anhydrases/acetyltransferases isoleucine patch superfamily-like protein SACE_3739 206 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 134103369 Nonpathogen - hypothetical protein SACE_6942 1 None None None 134097259 Common cloP O-methyltransferase SACE_0650 22 None None None 134097980 Nonpathogen - hypothetical protein SACE_1394 1 None None None 134102800 Common glcD glycolate oxidase subunit SACE_6366 202 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 134102829 Common - amidohydrolase 2 SACE_6395 21 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 134098064 Common - hypothetical protein SACE_1478 13 COG5450 COG5450, Transcription regulator of the Arc/MetJ class Transcription 134103014 Common - probable succinate dehydrogenase hydrophobic membrane anchor protein SACE_6583 13 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 134097678 Nonpathogen - hypothetical protein SACE_1082 1 None None None 134102010 Common - hypothetical protein SACE_5560 10 None None None 134098450 Nonpathogen - TetR-family transcriptional regulator SACE_1874 2 COG1309 AcrR, Transcriptional regulator Transcription 134097632 Nonpathogen - hypothetical protein SACE_1036 1 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 134100320 Common hemH ferrochelatase SACE_3785 110 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 134098851 Common - hypothetical protein SACE_2283 4 None None None 134101735 Common - two-component system response regulator SACE_5231 194 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134097137 Common pknJ serine/threonine kinase SACE_0526 155 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 134100936 Nonpathogen - hypothetical protein SACE_4403 1 None None None 134098536 Common - oxidoreductase SACE_1962 166 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 134099600 Common - hypothetical protein SACE_3058 7 None None None 134099280 Common fabG 3-oxoacyl-(acyl-carrier-protein) reductase SACE_2735 227 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 134096859 Nonpathogen - hypothetical protein SACE_0242 5 None None None 134097323 Common eryBVI NDP-4-keto-6-deoxy-glucose 2,3-dehydratase SACE_0717 9 None None None 134097983 Nonpathogen - hypothetical protein SACE_1397 1 None None None 134097815 Common - two-component system response regulator SACE_1225 210 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134102460 Common gabT 4-aminobutyrate aminotransferase, PLP-dependent SACE_6022 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 134102621 Nonpathogen - hypothetical protein SACE_6184 1 None None None 134097572 Nonpathogen - hypothetical protein SACE_0976 3 None None None 134098660 Nonpathogen - hypothetical protein SACE_2089 3 None None None 134099494 Common pfpI protease I SACE_2952 169 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 134102212 Common - putative transketolase SACE_5763 207 COG3959 COG3959, Transketolase, N-terminal subunit Carbohydrate transport and metabolism 134100137 Common - antibiotic resistance macrolide glycosyltransferase SACE_3599 46 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 162316924 Common tnaA tryptophanase SACE_1957 44 COG3033 TnaA, Tryptophanase Amino acid transport and metabolism 134102553 Common - hypothetical protein SACE_6116 8 None None None 134097550 Common sbcD putative ATP-dependent dsDNA exonuclease SACE_0952 83 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 134098092 Common dnaG DNA primase (bacterial type) SACE_1506 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 134096941 Common dnaN DNA polymerase III beta subunit SACE_0327 157 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 134100216 Nonpathogen - hypothetical protein SACE_3678 1 None None None 134097888 Common - hypothetical protein SACE_1301 7 COG3553 COG3553, Uncharacterized protein conserved in bacteria Function unknown 134097639 Common - hypothetical protein SACE_1043 12 None None None 134098613 Common - hypothetical protein SACE_2043 6 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 134099609 Common - hypothetical protein SACE_3067 7 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 134101433 Common - twin-arginine translocation pathway signal SACE_4903 23 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 134100826 Common - amidase SACE_4293 8 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 134101931 Common - SAM-dependent methyltransferase SACE_5432 167 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134101996 Nonpathogen - hypothetical protein SACE_5546 4 None None None 134102848 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) SACE_6414 191 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 134098086 Common glyS glycyl-tRNA synthetase SACE_1500 86 COG0423 GRS1, Glycyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 134097714 Common - NADH dehydrogenase SACE_1119 209 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 134103577 Nonpathogen - hypothetical protein SACE_7155 1 None None None 134101357 Common - putative LacI-family transcriptional regulator SACE_4828 125 COG1609 PurR, Transcriptional regulators Transcription 134103275 Common - PE-PGRS family protein SACE_6847 16 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 134098672 Common dfp DNA/pantothenate metabolism flavoprotein SACE_2102 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 134100354 Nonpathogen - hypothetical protein SACE_3819 1 None None None 134097892 Common - putative non-ribosomal peptide synthetase SACE_1305 218 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134096850 Common - CMP/dCMP deaminase, zinc-binding SACE_0233 202 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 134098218 Common - hypothetical protein SACE_1635 4 COG2367 PenP, Beta-lactamase class A Defense mechanisms 134101574 Common - carboxymuconolactone decarboxylase SACE_5050 51 COG2128 COG2128, Uncharacterized conserved protein Function unknown 134098233 Common cobT nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase SACE_1650 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 134103556 Common - conserved protein (PRC-barrel domain) SACE_7134 8 None None None 134103184 Nonpathogen - hypothetical protein SACE_6754 1 None None None 134103269 Common rpsL 30S ribosomal protein S12 SACE_6841 246 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 134101595 Nonpathogen - hypothetical protein SACE_5072 3 None None None 134096727 Common - protein of unknown function DUF867 SACE_0109 8 COG4195 COG4195, Phage-related replication protein General function prediction only 134101350 Common - peptide ABC transporter, ATP-binding protein SACE_4821 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 134103230 Common rplQ 50S ribosomal protein L17 SACE_6802 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 134101761 Common argR arginine repressor (partial match) SACE_5257 78 COG1438 ArgR, Arginine repressor Transcription 134102106 Nonpathogen - hypothetical protein SACE_5656 1 None None None 134099036 Common - multicopper oxidase type 1 SACE_2475 21 COG3391 COG3391, Uncharacterized conserved protein Function unknown 134099249 Common - hypothetical protein SACE_2703 9 None None None 134100298 Nonpathogen - hypothetical protein SACE_3763 2 None None None 134099242 Common - putative non-ribosomal peptide synthetase SACE_2696 221 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134100006 Common abaB2 LysR-family transcriptional regulator SACE_3468 159 COG0583 LysR, Transcriptional regulator Transcription 134098186 Nonpathogen - hypothetical protein SACE_1602 4 None None None 134098400 Nonpathogen - hypothetical protein SACE_1821 1 None None None 134096792 Common phoD phosphodiesterase/alkaline phosphatase D SACE_0175 60 COG3540 PhoD, Phosphodiesterase/alkaline phosphatase D Inorganic ion transport and metabolism 134098543 Nonpathogen - twin-arginine translocation pathway signal SACE_1969 8 None None None 134102355 Nonpathogen - hypothetical protein SACE_5908 1 None None None 134102934 Common - biotin--[acetyl-CoA-carboxylase] ligase SACE_6501 196 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 134099848 Nonpathogen - hypothetical protein SACE_3309 1 None None None 134102655 Common - thioredoxin SACE_6218 230 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 134103625 Common - hypothetical protein SACE_7203 12 COG1846 MarR, Transcriptional regulators Transcription 134098181 Nonpathogen - hypothetical protein SACE_1597 2 None None None 134100244 Common - abhydrolase, alpha/beta hydrolase fold SACE_3708 9 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134102641 Common - possible transferase SACE_6204 111 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 134098735 Common - hypothetical protein SACE_2165 4 None None None 134101133 Common - oxidoreductase, short-chain dehydrogenase/reductase family SACE_4600 232 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 134096668 Common - FHA domain containing protein SACE_0050 37 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 134103670 Nonpathogen - hypothetical protein SACE_7248 1 None None None 134099706 Common - lysine exporter protein (LysE/YggA) SACE_3166 95 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 134100508 Nonpathogen - hypothetical protein SACE_3973 3 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 134099538 Common - hydrolase, TatD family SACE_2996 24 COG1099 COG1099, Predicted metal-dependent hydrolases with the TIM-barrel fold General function prediction only 134099946 Common - transcriptional regulator, TetR family SACE_3407 35 COG1309 AcrR, Transcriptional regulator Transcription 134100756 Nonpathogen - uncharacterized membrane-associated protein-like SACE_4223 1 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 134103569 Common - beta-lactamase-like protein SACE_7147 42 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 134097520 Common - acetyltransferase, GNAT family SACE_0922 33 COG0456 RimI, Acetyltransferases General function prediction only 134101055 Common - probable multidrug resistance transporter, MFS superfamily SACE_4522 18 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 134100812 Common - non-ribosomal peptide synthetase/polyketide synthase SACE_4279 210 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134097018 Common - NAD-dependent glycerol-3-phosphate dehydrogenase-like protein SACE_0405 46 COG5495 COG5495, Uncharacterized conserved protein Function unknown 134099724 Common - hypothetical protein SACE_3184 3 COG5050 EPT1, sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferases Lipid metabolism 134096836 Common acsA acetoacetyl-CoA synthetase SACE_0219 203 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 134098333 Common - hypothetical protein SACE_1751 7 None None None 134099926 Common baiB bile acid-coenzyme A ligase SACE_3387 215 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134102456 Common lao2 L-amino-acid oxidase SACE_6018 49 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 134098511 Common - 2-hydroxy-3-oxopropionate reductase SACE_1936 196 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 134101605 Common - transposase SACE_5084 63 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134096742 Common - possible membrane protein SACE_0124 3 None None None 134100787 Common - putative ABC transporter substrate-binding protein SACE_4254 102 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 134098040 Common - RNA polymerase ECF sigma factor SACE_1454 71 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 134099313 Nonpathogen - hypothetical protein SACE_2768 1 None None None 134097014 Common - MerR-family transcriptional regulator SACE_0401 128 COG0789 SoxR, Predicted transcriptional regulators Transcription 134101741 Common - pseudouridylate synthase ribosomal large subunit SACE_5237 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 134102020 Common - putative sugar isomerase SACE_5570 121 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 134100130 Common - hypothetical protein SACE_3592 8 None None None 134099278 Common - alcohol dehydrogenase, zinc-binding SACE_2733 213 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 134101212 Nonpathogen - hypothetical protein SACE_4680 4 COG3899 COG3899, Predicted ATPase General function prediction only 134103336 Common paaC,ydbP phenylacetic acid degradation protein SACE_6909 39 COG3396 COG3396, Uncharacterized conserved protein Function unknown 134100886 Common - phosphatidylethanolamine N-methyltransferase SACE_4353 51 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134097696 Common - PDZ/DHR/GLGF SACE_1100 61 COG3480 SdrC, Predicted secreted protein containing a PDZ domain Signal transduction mechanisms 134101503 Common - protein of unknown function DUF181 SACE_4975 4 COG1944 COG1944, Uncharacterized conserved protein Function unknown 134103687 Common - hypothetical protein SACE_7265 4 None None None 134098259 Common - methyltransferase type 12 SACE_1676 46 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134103807 Common - hypothetical protein SACE_7387 11 None None None 134097200 Nonpathogen - hypothetical protein SACE_0590 3 None None None 134100414 Common arcB1 ornithine cyclodeaminase SACE_3879 64 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 134097083 Nonpathogen - hypothetical protein SACE_0469 2 None None None 134100866 Common - GCN5-related N-acetyltransferase SACE_4333 4 COG0456 RimI, Acetyltransferases General function prediction only 134100976 Common - NAD/factor-dependent formaldehyde dehydrogenase SACE_4443 163 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 134102768 Common - SSS sodium solute transporter superfamily SACE_6333 142 COG4147 DhlC, Predicted symporter General function prediction only 134099304 Common - hypothetical protein SACE_2759 5 None None None 134098931 Common fadD2 acyl-CoA synthase SACE_2367 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134102919 Common purK phosphoribosylaminoimidazole carboxylase ATPase subunit SACE_6486 195 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 134101817 Common uvrA excinuclease ABC subunit A SACE_5314 237 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 134099896 Common - GntR-family transcriptional regulator SACE_3357 39 COG2186 FadR, Transcriptional regulators Transcription 134100897 Common - putative 2-haloalkanoic acid dehalogenase SACE_4364 58 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 134100073 Common - putative GAF sensor protein SACE_3535 2 None None None 134100677 Common - cytochrome P450 monooxygenase SACE_4144 83 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134103305 Common rpmG 50S ribosomal protein L33 type 2 SACE_6877 79 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 134102516 Common - putative multidrug resistance efflux protein SACE_6079 110 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134101028 Common glyA2 serine hydroxymethyltransferase SACE_4495 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 134096776 Common - endonuclease III-like protein SACE_0159 11 None None None 134097548 Common - lipase SACE_0950 96 COG0657 Aes, Esterase/lipase Lipid metabolism 134099011 Common - hypothetical protein SACE_2449 16 None None None 134101155 Common - putative aminobenzoyl-glutamate transporter SACE_4622 43 COG2978 AbgT, Putative p-aminobenzoyl-glutamate transporter Coenzyme metabolism 134097541 Common - binding protein/LacI transcriptional regulator SACE_0943 102 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 134098082 Common - permease SACE_1496 31 COG0701 COG0701, Predicted permeases General function prediction only 134103663 Common tipA MerR-family transcriptional regulator SACE_7241 134 COG0789 SoxR, Predicted transcriptional regulators Transcription 134102462 Common ogt methylated-DNA--protein-cysteine methyltransferase SACE_6024 218 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 134102247 Common - conserved hypothetical membrane permease protein SACE_5799 13 COG0730 COG0730, Predicted permeases General function prediction only 134101246 Common - 6-O-methylguanine DNA methyltransferase SACE_4714 20 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134103802 Common sigT putative RNA polymerase sigma factor SACE_7382 171 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 134097557 Common - translation-associated GTPase SACE_0960 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 134097671 Common - possible DNA-methyltransferase (modification methylase) SACE_1075 67 COG3695 COG3695, Predicted methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 134100113 Common - cobyric acid synthase SACE_3575 123 COG3442 COG3442, Predicted glutamine amidotransferase General function prediction only 134098412 Common hemE uroporphyrinogen decarboxylase (partial match) SACE_1836 177 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 134098841 Common - transcriptional regulator, DeoR family SACE_2272 115 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 134099324 Common - major facilitator superfamily (MFS_1) transporter SACE_2779 130 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134102318 Common - transglutaminase-like SACE_5871 100 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 134101148 Common - putative ATP-binding component of an ABC transport protein SACE_4615 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 134101521 Common - putative AraC-family transcriptional regulator SACE_4993 96 COG3708 COG3708, Uncharacterized protein conserved in bacteria Function unknown 134100729 Common rsbW anti-sigma factor SACE_4196 11 None None None 134098674 Common - secreted trypsin-like serine protease SACE_2104 30 COG5640 COG5640, Secreted trypsin-like serine protease Posttranslational modification, protein turnover, chaperones 134099640 Common - sugar transporter, MFS superfamily SACE_3098 137 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134102957 Common - tetratricopeptide TPR_2 SACE_6524 20 None None None 134097607 Common dapC N-succinyldiaminopimelate aminotransferase SACE_1011 236 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 134098200 Common - Transposase, mutator type SACE_1616 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 134100141 Common - aminoglycoside acetyltransferase SACE_3603 17 COG2746 COG2746, Aminoglycoside N3'-acetyltransferase Defense mechanisms 134099383 Common - IS1647-like transposase SACE_2840 32 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134100609 Common - AsnC-family transcriptional regulator SACE_4074 155 COG1522 Lrp, Transcriptional regulators Transcription 134102543 Common coaD pantetheine-phosphate adenylyltransferase SACE_6106 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 134098314 Common - hypothetical protein SACE_1732 234 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 134103702 Common xylR transcriptional regulator, ROK family SACE_7280 152 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 134097225 Common - transcriptional repressor, CopY family SACE_0615 45 COG3682 COG3682, Predicted transcriptional regulator Transcription 134096690 Common mphB macrolide 2'-phosphotransferase SACE_0072 16 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 134098047 Common - guanine-specific ribonuclease N1 and T1 SACE_1461 25 COG4290 COG4290, Guanyl-specific ribonuclease Sa Nucleotide transport and metabolism 134103799 Common - possible glycoprotein SACE_7379 14 None None None 134102770 Common - hypothetical protein SACE_6336 16 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 134102405 Common - hypothetical protein SACE_5959 7 None None None 134097197 Common - hypothetical protein SACE_0587 7 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 134099101 Common - hypothetical protein SACE_2546 49 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 134099812 Common corA magnesium and cobalt transport protein CorA SACE_3273 161 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 134099089 Common greA transcription elongation factor G SACE_2533 18 COG0782 GreA, Transcription elongation factor Transcription 134097220 Common - xanthine/uracil/vitamin C permease SACE_0610 135 COG2252 COG2252, Permeases General function prediction only 134099958 Common pydB dihydropyrimidinase SACE_3419 193 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 134099043 Common - pyruvate, water dikinase SACE_2483 157 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 134096886 Nonpathogen - hypothetical protein SACE_0271 1 None None None 134098533 Nonpathogen - hypothetical protein SACE_1958 3 None None None 134099052 Common - regulator SACE_2495 24 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 134098903 Common cmtC trehalose corynomycolyl transferase C SACE_2339 10 COG0627 COG0627, Predicted esterase General function prediction only 134097103 Common - lipolytic enzyme, G-D-S-L family SACE_0489 15 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 134100848 Nonpathogen - hypothetical protein SACE_4315 11 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 134098139 Common - hypothetical protein SACE_1553 41 COG4336 COG4336, Uncharacterized conserved protein Function unknown 134102785 Common - putative phytoene synthase SACE_6351 57 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 134102760 Common - hypothetical protein SACE_6325 67 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 134103485 Common - NmrA-like protein SACE_7060 52 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 134096707 Nonpathogen - hypothetical protein SACE_0089 1 None None None 134098125 Common - secreted protein SACE_1539 14 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 134103696 Common pckA phosphoenolpyruvate carboxykinase SACE_7274 59 COG1274 PckA, Phosphoenolpyruvate carboxykinase (GTP) Energy production and conversion 134101418 Nonpathogen - hypothetical protein SACE_4888 2 None None None 134100483 Common - transcriptional regulator, IclR family SACE_3948 67 COG1414 IclR, Transcriptional regulator Transcription 134100771 Common - transposase for IS3518 SACE_4238 143 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 134101388 Common - lysine exporter protein (LysE/YggA) SACE_4858 74 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 134100823 Common gatA amidase SACE_4290 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 134098381 Common ppgK polyphosphate glucokinase SACE_1802 92 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 134100420 Common - MerR-family transcriptional regulator SACE_3885 68 COG0789 SoxR, Predicted transcriptional regulators Transcription 134101381 Common - protein kinase/transcriptional regulator, LuxR family SACE_4851 97 COG3903 COG3903, Predicted ATPase General function prediction only 134099284 Common - proline/betaine transporter, MFS family SACE_2739 121 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134099939 Common - acetyl/propionyl-CoA carboxylase alpha subunit SACE_3400 238 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 134098664 Common - putative lysophospholipase SACE_2093 45 COG2267 PldB, Lysophospholipase Lipid metabolism 134101501 Common - ferritin family protein SACE_4973 69 COG1528 Ftn, Ferritin-like protein Inorganic ion transport and metabolism 134097609 Common dapD 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase SACE_1013 39 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 134099338 Common - hypothetical protein SACE_2793 19 COG0789 SoxR, Predicted transcriptional regulators Transcription 134101946 Nonpathogen - hypothetical protein SACE_5448 1 None None None 134098299 Common - hypothetical protein SACE_1717 2 None None None 134101311 Nonpathogen - hypothetical protein SACE_4779 1 None None None 134098912 Nonpathogen - hypothetical protein SACE_2348 2 None None None 134097065 Common fhuC ABC transporter, ATP-binding protein SACE_0452 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 134098020 Common - hypothetical protein SACE_1434 42 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 134098254 Common - FAD-binding monooxygenase, PheA/TfdB family SACE_1671 85 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 134097925 Nonpathogen - two-component response regulator SACE_1338 4 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 134101872 Common - TetR-family transcriptional regulator SACE_5370 15 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 134098962 Common - phosphoribosyltransferase SACE_2400 68 COG1926 COG1926, Predicted phosphoribosyltransferases General function prediction only 134099199 Common - alcohol dehydrogenase, zinc-binding SACE_2652 144 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 134097829 Nonpathogen - integral membrane protein SACE_1240 2 None None None 134098838 Common blaB2 metallo-beta-lactamase SACE_2269 49 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 134096807 Common - two-component system response regulator SACE_0190 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 134102210 Common hisH imidazole glycerol phosphate synthase subunit HisH SACE_5761 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 134098282 Common glk glucokinase, transcriptional regulator SACE_1700 161 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 134101557 Nonpathogen - secreted protein SACE_5033 2 None None None 134101623 Common - hypothetical protein SACE_5109 13 COG1337 COG1337, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 134097210 Common - putative DNA-binding protein SACE_0600 6 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 134101326 Nonpathogen - hypothetical protein SACE_4796 1 None None None 134103279 Common - carboxylesterase SACE_6851 82 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134103601 Common - hypothetical protein SACE_7179 14 None None None 134102130 Common - transcriptional regulator, GntR family SACE_5680 113 COG1802 GntR, Transcriptional regulators Transcription 134097749 Common - proton antiporter efflux pump SACE_1157 176 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134100838 Common - peptide carrier protein SACE_4305 15 None None None 134098458 Common - inner-membrane translocator SACE_1882 112 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 134096635 Common - hypothetical protein SACE_0017 33 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 134099132 Common - bicyclomycin resistance protein TcaB SACE_2577 168 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134100373 Common - probable ABC cobalt transporter, permease component SACE_3838 28 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 134102073 Common - hypothetical protein SACE_5623 25 COG3506 COG3506, Uncharacterized conserved protein Function unknown 134101462 Nonpathogen - hypothetical protein SACE_4932 2 COG3224 COG3224, Uncharacterized protein conserved in bacteria Function unknown 134097718 Common - C-5 cytosine-specific DNA methylase SACE_1123 114 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 134097474 Common - hypothetical protein SACE_0874 8 None None None 134098779 Nonpathogen - hypothetical protein SACE_2209 1 None None None 134103653 Nonpathogen - hypothetical protein SACE_7231 1 None None None 134097001 Common - pyruvate, water dikinase SACE_0388 165 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 134101968 Common - PE-PGRS family protein SACE_5512 14 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 134100512 Common - terpene synthase, metal binding domain protein SACE_3977 10 None None None 134101979 Common - hypothetical protein SACE_5523 4 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 134103312 Common - probable protease htpX homolog SACE_6884 189 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 134097764 Nonpathogen - hypothetical protein SACE_1172 1 None None None 134103053 Common - transposase SACE_6623 64 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134100523 Common - hypothetical protein SACE_3988 9 None None None 134099439 Common - methyltransferase type 12 SACE_2897 2 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 134098149 Nonpathogen - hypothetical protein SACE_1563 7 None None None 134099915 Nonpathogen - hypothetical protein SACE_3376 1 None None None 134097699 Nonpathogen - hypothetical protein SACE_1103 1 None None None 134099854 Common - hypothetical protein SACE_3315 15 COG5243 HRD1, HRD ubiquitin ligase complex, ER membrane component Posttranslational modification, protein turnover, chaperones 134102980 Common pmmB putative phospho-sugar mutase SACE_6548 151 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 134100761 Nonpathogen - hypothetical protein SACE_4228 1 None None None 134098787 Common - putative oxidoreductase SACE_2218 96 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 134100578 Nonpathogen - hypothetical cytosolic protein SACE_4043 2 None None None 134098924 Common mce5C putative Mce family protein SACE_2360 7 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 134100588 Common - transport-protein, putative permease for cytosine/purines SACE_4053 11 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 134102395 Nonpathogen - hypothetical protein SACE_5948 2 None None None 134099110 Common - two component transcriptional regulator, LuxR family SACE_2555 127 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134102119 Common - amino acid transporter, APC family SACE_5669 122 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 134103012 Common - ABC transporter substrate-binding protein SACE_6580 105 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 134103349 Nonpathogen - hypothetical protein SACE_6922 1 None None None 134099907 Common - methylated-DNA-(protein)-cysteine S-methyltransferase SACE_3368 4 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 134102559 Common dak3 putative dihydroxyacetone kinase SACE_6122 49 COG1461 COG1461, Predicted kinase related to dihydroxyacetone kinase General function prediction only 134100655 Common - drug resistance transporter EmrB/QacA subfamily SACE_4121 174 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134102598 Common ilvD dihydroxy-acid dehydratase SACE_6161 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 134098818 Common - putative proteasome component SACE_2249 16 None None None 134101591 Common - possible transcriptional regulator, GntR family SACE_5068 132 COG1802 GntR, Transcriptional regulators Transcription 134097321 Common eryCV EryCV NDP-4,6-dideoxyhexose 3,4-enoyl reductase SACE_0715 10 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 134098792 Common - glycine betaine transport system permease protein SACE_2223 69 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 134103780 Common - hypothetical protein SACE_7360 159 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 134101342 Nonpathogen - hypothetical protein SACE_4813 1 None None None 134100035 Common - probable transcriptional regulator, MarR family SACE_3497 25 COG1846 MarR, Transcriptional regulators Transcription 134099480 Nonpathogen - hypothetical protein SACE_2938 1 None None None 134101920 Common uvrB excinuclease ABC subunit B SACE_5421 224 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 134097513 Common - probable PhoH-like phosphate starvation-induced protein SACE_0915 199 COG1875 COG1875, Predicted ATPase related to phosphate starvation-inducible protein PhoH Signal transduction mechanisms 134099698 Common - putative signal-transduction protein with CBS domains SACE_3157 199 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 134102998 Common - putatively membrane-anchored aldehyde dehydrogenase protein SACE_6566 191 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 134098721 Common trkA potassium uptake protein SACE_2151 114 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 134100066 Common - membrane protein, putative (partial match) SACE_3528 17 COG0730 COG0730, Predicted permeases General function prediction only 134099746 Common - oxidoreductase domain protein SACE_3207 145 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 134102272 Common lspA lipoprotein signal peptidase SACE_5824 39 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 134100293 Nonpathogen - hypothetical protein SACE_3758 1 None None None 134103681 Common - putative ABC transporter membrane protein SACE_7259 6 None None None 134102838 Common - N-formimino-L-glutamate deiminase SACE_6404 144 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 134097394 Common - two-component system sensor kinase SACE_0788 33 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 134101361 Common - hypothetical protein SACE_4832 5 None None None 134102056 Common - zinc finger, UBP-type SACE_5606 23 COG5207 UBP14, Isopeptidase T Posttranslational modification, protein turnover, chaperones 134103370 Common hemB delta-aminolevulinic acid dehydratase SACE_6943 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 134102947 Nonpathogen - hypothetical protein SACE_6514 1 None None None 134098019 Common - probable phosphoglycerate mutase (phosphoglyceromutase) SACE_1433 173 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 134102537 Common rnc ribonuclease III SACE_6100 209 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 134100471 Common - 3-oxoacyl-[acyl-carrier protein] reductase SACE_3936 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134101706 Common lpsA1 secreted lipase SACE_5200 34 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 134099295 Common - putative acyl-CoA synthetase SACE_2750 219 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134103062 Common - putative oxygen-dependent FAD-linked oxidoreductase SACE_6632 36 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 134100680 Common - secreted protein SACE_4147 14 None None None 134102118 Common - betaine-aldehyde dehydrogenase SACE_5668 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 134101177 Common - putative glycosyltransferase SACE_4644 47 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 134101510 Common - integral membrane transport protein SACE_4982 30 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134102002 Nonpathogen - hypothetical protein SACE_5552 1 None None None 134097311 Common - lysozyme M1 precursor SACE_0704 40 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 134103225 Common - hypothetical protein SACE_6797 7 None None None 134103570 Nonpathogen - AAA ATPase containing von Willebrand factor type A (vWA) domain-like protein SACE_7148 1 None None None 134099253 Common - bifunctional deaminase-reductase-like SACE_2707 41 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 134097736 Common - transcriptional regulator, XRE family SACE_1141 7 COG1396 HipB, Predicted transcriptional regulators Transcription 134098877 Nonpathogen - hypothetical protein SACE_2312 2 None None None 134102492 Common - probable conserved integral membrane protein SACE_6055 2 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 134099553 Common - probable copper resistance transporter SACE_3011 14 COG3336 COG3336, Predicted membrane protein Function unknown 134100238 Common otsB2 putative trehalose-6-phosphate phosphatase SACE_3700 81 COG1877 OtsB, Trehalose-6-phosphatase Carbohydrate transport and metabolism 134099709 Common - hypothetical protein SACE_3169 7 None None None 134099702 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) SACE_3161 189 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 134101723 Common eryA putative erythritol kinase protein SACE_5218 174 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 134099207 Common - hypothetical protein SACE_2660 9 None None None 134103267 Common fusA putative translation elongation factor G SACE_6839 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 134103169 Nonpathogen - hypothetical protein SACE_6739 1 None None None 134097832 Common rppA putative type III polyketide synthase SACE_1243 48 COG3424 BcsA, Predicted naringenin-chalcone synthase Secondary metabolites biosynthesis, transport, and catabolism 134100297 Nonpathogen - hypothetical protein SACE_3762 1 None None None 134096861 Nonpathogen - hypothetical protein SACE_0245 1 None None None 134099180 Common ehpF putative phenazine antibiotic biosynthesis protein SACE_2632 8 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 134096694 Common - glycine betaine transporter, BCCT family SACE_0076 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 134097803 Common - Ham1-like protein SACE_1213 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 134102502 Common - putative muramoyl-pentapeptide carboxypeptidase SACE_6065 19 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 134098326 Common - amino acid ABC transporter, permease protein SACE_1744 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 134096681 Common - FAD-linked oxidoreductase SACE_0063 31 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 134099401 Common - hypothetical protein SACE_2859 32 COG4995 COG4995, Uncharacterized protein conserved in bacteria Function unknown 134103071 Common - NADPH:quinone reductase or related Zn-dependent oxidoreductase SACE_6641 147 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 134101892 Common - TetR-family transcriptional regulator SACE_5390 129 COG1309 AcrR, Transcriptional regulator Transcription 134102704 Common - putative amino acid ABC transporter permease protein SACE_6268 171 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 134102794 Common - transcriptional regulator (TetR/AcrR family) SACE_6360 123 COG1309 AcrR, Transcriptional regulator Transcription 134096952 Common - hypothetical protein SACE_0338 9 None None None 134097108 Common - ATPase, BadF/BadG/BcrA/BcrD type SACE_0495 55 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 134098604 Common - putative peptidyl-prolyl cis-trans isomerase SACE_2030 137 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 134098749 Common - predicted metal-sulfur cluster biosynthetic enzyme SACE_2179 129 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 134097685 Common - peptidase M16-like SACE_1089 188 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 134098096 Nonpathogen - hypothetical protein SACE_1510 1 None None None 134101786 Common - lysine exporter protein (LysE/YggA) SACE_5283 116 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 134103508 Common - superoxide dismutase, copper/zinc binding SACE_7084 5 None None None 134100994 Nonpathogen - hypothetical protein SACE_4461 1 None None None 134103116 Nonpathogen - hypothetical protein SACE_6686 1 None None None 134099377 Common - secreted amidase SACE_2834 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 134103387 Common - diacylglycerol kinase catalytic domain-containing protein SACE_6961 8 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 134097247 Common ureF putative urease accessory protein SACE_0637 8 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 134098031 Common - hypothetical protein SACE_1445 17 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134103033 Common - transposase Tn3 family protein SACE_6602 10 None None None 134099183 Common - MFS transporter, phthalate permease family SACE_2635 186 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 134100061 Nonpathogen - hypothetical protein SACE_3523 1 None None None 134102853 Nonpathogen sodN superoxide dismutase SACE_6419 13 None None None 134100600 Common - ATP/GTP-binding protein SACE_4065 11 None None None 134102200 Nonpathogen - hypothetical protein SACE_5751 1 None None None 134097341 Nonpathogen - hypothetical protein SACE_0735 1 None None None 134098443 Nonpathogen - hypothetical protein SACE_1867 3 None None None 134101230 Common - hypothetical protein SACE_4698 12 None None None 134103464 Common accD1 propionyl-CoA carboxylase, beta subunit SACE_7039 143 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 134103233 Common rpsK 30S ribosomal protein S11 SACE_6805 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 134096905 Common - cytidine/deoxycytidylate deaminase, zinc-binding region SACE_0291 149 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 134097308 Common - ArsR-family transcriptional regulator SACE_0701 35 COG0640 ArsR, Predicted transcriptional regulators Transcription 134097571 Common - hypothetical protein SACE_0975 16 COG5637 COG5637, Predicted integral membrane protein Function unknown 134103019 Common - monooxygenase, FAD-binding SACE_6588 119 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 134097874 Common - ABC Fe(3+) transporter, substrate binding component SACE_1287 87 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 134100391 Common accD3 putative acetyl CoA carboxylase beta subunit SACE_3856 213 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 134103148 Nonpathogen - hypothetical protein SACE_6718 1 None None None 134099941 Common - probable ribosomal protein N-acetyltransferase SACE_3402 36 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 134097848 Common - xanthine/uracil/vitamin C permease SACE_1259 135 COG2252 COG2252, Permeases General function prediction only 134098209 Common lipA lipoyl synthase SACE_1626 193 COG0320 LipA, Lipoate synthase Coenzyme metabolism 134100402 Common - thioesterase-like protein SACE_3867 30 COG0824 FcbC, Predicted thioesterase General function prediction only 134100748 Common - putative methyltransferase SACE_4215 32 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134100831 Nonpathogen - hypothetical protein SACE_4298 1 None None None 134098744 Common sufB putative iron-regulated ABC-type transporter SACE_2174 186 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 134100598 Common - metabolite transporter, MFS superfamily SACE_4063 116 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134100800 Common - hypothetical protein SACE_4267 10 None None None 134097233 Common - hypothetical protein SACE_0623 20 None None None 134100933 Common - transcriptional regulator, LysR family SACE_4400 154 COG0583 LysR, Transcriptional regulator Transcription 134103688 Common - isoniazid inductible gene protein IniC SACE_7266 26 COG1159 Era, GTPase General function prediction only 134099351 Common - hypothetical protein SACE_2808 9 None None None 134102974 Common - putative monovalent cation/H+ antiporter subunit D SACE_6542 208 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 134101653 Common - probable transcriptional regulator, ArsR family SACE_5144 179 COG0640 ArsR, Predicted transcriptional regulators Transcription 134103085 Common - pentapeptide repeat family protein SACE_6655 80 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 134097419 Common - natural resistance-associated macrophage protein SACE_0814 26 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 134100708 Nonpathogen - hypothetical protein SACE_4175 1 None None None 134099512 Nonpathogen - hypothetical protein SACE_2970 1 None None None 134097383 Common - hypothetical protein SACE_0777 4 None None None 134097555 Common - hypothetical protein SACE_0958 2 None None None 134103284 Common - hypothetical protein SACE_6856 5 None None None 134099570 Nonpathogen - hypothetical protein SACE_3028 2 None None None 134099581 Common - IclR-type transcriptional regulator SACE_3039 49 COG1414 IclR, Transcriptional regulator Transcription 134101671 Common - hypothetical protein SACE_5163 15 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134102606 Nonpathogen - hypothetical protein SACE_6169 4 None None None 134101998 Nonpathogen - hypothetical protein SACE_5548 1 None None None 134097177 Common - secreted protein SACE_0567 17 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 134102696 Common aglA alpha-glucosidase SACE_6260 164 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 134097262 Common - hypothetical protein SACE_0653 12 None None None 134101354 Common - protein of unknown function DUF1130 SACE_4825 46 COG5483 COG5483, Uncharacterized conserved protein Function unknown 134099625 Common - NmrA family protein SACE_3083 121 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 134099802 Common - ABC transporter, ATP-binding component SACE_3263 247 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 134099073 Common - putative transposase SACE_2516 27 None None None 134101103 Common pksG hydroxymethylglutaryl-CoA synthase SACE_4570 42 COG3425 PksG, 3-hydroxy-3-methylglutaryl CoA synthase Lipid metabolism 134097562 Common - 3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase SACE_0966 92 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134103130 Common - secreted protein SACE_6700 46 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 134103766 Common - acetyl transferase SACE_7346 63 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 134102740 Common - probable transcriptional regulator, LytR family SACE_6305 63 COG1316 LytR, Transcriptional regulator Transcription 134099142 Common - short-chain dehydrogenase/reductase SDR SACE_2587 229 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134099311 Common - NAD-dependent epimerase/dehydratase SACE_2766 17 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 134097655 Common - conserved hypothetical alanine valine rich protein SACE_1059 5 None None None 134101306 Common - LysR-family transcriptional regulator SACE_4774 185 COG0583 LysR, Transcriptional regulator Transcription 134097231 Common - ABC iron transporter, permease component SACE_0621 177 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 134097753 Common - putative carbon monoxide dehydrogenase small chain SACE_1161 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 134099592 Common - hypothetical protein SACE_3050 5 COG4270 COG4270, Predicted membrane protein Function unknown 134101705 Common - putative zinc finger protein SACE_5199 23 COG1656 COG1656, Uncharacterized conserved protein Function unknown 134103623 Common - integral membrane transport protein SACE_7201 85 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 134099413 Common rifL putative oxidoreductase SACE_2871 117 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 134103787 Common - two-component system response regulator SACE_7367 220 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134097440 Common - similar to membrane-bound lytic murein transglycosylase B SACE_0835 14 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 134102339 Common - secreted peptidase SACE_5892 38 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134102987 Common - death-on-curing protein SACE_6555 12 COG3654 Doc, Prophage maintenance system killer protein General function prediction only 134097006 Common - hypothetical protein SACE_0393 27 COG5282 COG5282, Uncharacterized conserved protein Function unknown 134103478 Nonpathogen - hypothetical protein SACE_7053 1 None None None 134102417 Common - secreted trypsin-like serine protease SACE_5971 32 COG5640 COG5640, Secreted trypsin-like serine protease Posttranslational modification, protein turnover, chaperones 134097076 Common - possible amino acid export carrier protein SACE_0463 21 COG2966 COG2966, Uncharacterized conserved protein Function unknown 134097148 Common - carbon monoxide dehydrogenase large subunit SACE_0537 113 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 134100720 Common - amidohydrolase SACE_4187 45 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 134101901 Nonpathogen - putative integral membrane protein SACE_5400 5 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 134101938 Common - putative two-component system response regulator SACE_5439 224 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 134099796 Common - sugar phosphate isomerase/epimerase SACE_3257 11 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 134100875 Common - transcriptional regulator, IclR family/regucalcin SACE_4342 83 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 134101124 Common - transcriptional regulator, LacI family SACE_4591 126 COG1609 PurR, Transcriptional regulators Transcription 134101981 Common - transposase SACE_5526 4 None None None 134097457 Common - putative transcriptional regulator SACE_0852 36 COG3832 COG3832, Uncharacterized conserved protein Function unknown 134100409 Nonpathogen - hypothetical protein SACE_3874 4 None None None 134098350 Common - hypothetical protein SACE_1769 61 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 134097770 Nonpathogen - hypothetical protein SACE_1180 2 None None None 134103552 Common - transcriptional regulator, XRE family SACE_7130 6 None None None 134097188 Common - acyl-CoA synthetase SACE_0578 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134099995 Common rhtB homoserine/threonine efflux protein SACE_3457 118 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 134096627 Common gyrA DNA gyrase subunit A SACE_0009 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 134102614 Common ligA NAD-dependent DNA ligase LigA SACE_6177 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 134097047 Common - hypothetical protein SACE_0434 7 None None None 134102845 Common - amino acid ABC transporter, permease protein SACE_6411 35 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 134097410 Common - putative ABC transport system permease protein SACE_0805 92 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 134098889 Common tnpA Tn5045 transposase SACE_2325 26 None None None 134099048 Nonpathogen - hypothetical protein SACE_2491 1 None None None 134096934 Common - endoribonuclease L-PSP SACE_0320 88 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 134102253 Common - peptidase S16, lon-like SACE_5805 90 COG2802 COG2802, Uncharacterized protein, similar to the N-terminal domain of Lon protease General function prediction only 134097866 Common - ABC transporter related SACE_1277 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 134097518 Common - channel protein, hemolysin III family SACE_0920 55 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 134098398 Nonpathogen - hypothetical protein SACE_1819 1 None None None 134099827 Nonpathogen - hypothetical protein SACE_3288 3 None None None 134098569 Common - putative flavoprotein monooxygenase acting on aromatic compound SACE_1995 75 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 134101043 Common oxyS transcriptional regulator (LysR family) SACE_4510 178 COG0583 LysR, Transcriptional regulator Transcription 134100841 Nonpathogen - hypothetical protein SACE_4308 1 None None None 134096685 Nonpathogen - hypothetical protein SACE_0067 1 None None None 134100636 Common - mandelate racemase/muconate lactonizing enzyme SACE_4102 55 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 134096734 Common - possible signal peptide peptidase SACE_0116 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 134100807 Common - putative transport integral membrane protein SACE_4274 131 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 134103659 Common - camphor resistance CrcB protein SACE_7237 137 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 134099062 Common - peptidase M50 SACE_2505 58 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 134098221 Common sucB dihydrolipoamide succinyltransferase SACE_1638 194 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 134101763 Common argD acetylornithine aminotransferase SACE_5259 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 134102916 Common - hypothetical protein SACE_6483 14 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 134103211 Common - hypothetical protein SACE_6782 4 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 134103560 Common - lysozyme M1 precursor SACE_7138 39 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 134099472 Nonpathogen - hypothetical protein SACE_2930 1 None None None 134103353 Common - excisionase/Xis, DNA-binding SACE_6926 13 COG2452 COG2452, Predicted site-specific integrase-resolvase DNA replication, recombination, and repair 134099141 Common - rrf2 family protein SACE_2586 76 COG1959 COG1959, Predicted transcriptional regulator Transcription 134101857 Common glnA4 putative glutamine synthetase SACE_5355 224 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 134103158 Common glxK putative glycerate kinase SACE_6728 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 134098028 Common - cold-shock DNA-binding domain protein SACE_1442 181 COG1278 CspC, Cold shock proteins Transcription 134103042 Common - protein of unknown function DUF156 SACE_6612 85 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 134097287 Nonpathogen - hypothetical protein SACE_0680 1 None None None 134103129 Common - hypothetical protein SACE_6699 8 COG2320 GrpB, Uncharacterized conserved protein Function unknown 134100097 Common - pyridoxamine 5'-phosphate oxidase-related,FMN-binding protein SACE_3559 47 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 134100323 Common - D-lactate dehydrogenase (cytochrome) SACE_3788 200 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 134098439 Nonpathogen - hypothetical protein SACE_1863 1 COG3915 COG3915, Uncharacterized protein conserved in bacteria Function unknown 134100703 Common - iron-sulfur binding oxidoreductase SACE_4170 69 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 134102591 Common leuB beta-isopropylmalate dehydrogenase SACE_6154 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 134102908 Common - glycosyl transferase, group 2 family protein SACE_6475 84 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 134101565 Common - acyl-CoA dehydrogenase-like protein SACE_5041 148 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134103046 Nonpathogen - hypothetical protein SACE_6616 1 None None None 134096964 Nonpathogen - hypothetical protein SACE_0350 1 None None None 134098488 Common fabG3 3-oxoacyl-[acyl-carrier protein] reductase SACE_1913 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134101832 Common - putative transcriptional regulator SACE_5329 8 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 134098431 Common - possible transmembrane protein SACE_1855 7 None None None 134100741 Nonpathogen - hypothetical protein SACE_4208 1 None None None 134098521 Common - putative alcohol dehydrogenase (zinc-binding) SACE_1946 209 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 134098555 Common - protein kinase/transcriptional regulator, LuxR family SACE_1981 74 COG3903 COG3903, Predicted ATPase General function prediction only 134098893 Common yybE positive Regulator of yybF (LysR family) SACE_2329 190 COG0583 LysR, Transcriptional regulator Transcription 134098394 Common dxs 1-deoxy-D-xylulose-5-phosphate synthase SACE_1815 204 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 134097703 Common ftsX putative cell division membrane protein SACE_1107 69 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 134098943 Common - 1,3-propanediol dehydrogenase SACE_2379 171 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 134097933 Nonpathogen - hypothetical protein SACE_1346 2 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 134102684 Common dak2 dihydroxyacetone kinase SACE_6247 70 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 134098032 Common lepA GTP-binding protein LepA SACE_1446 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 134097359 Common rpmG 50S ribosomal protein L33 SACE_0753 128 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 134102833 Common - protein of unknown function DUF899,thioredoxin-like SACE_6399 26 COG4312 COG4312, Uncharacterized protein conserved in bacteria Function unknown 134098038 Common - O-methyltransferase SACE_1452 31 None None None 134101619 Common - hypothetical protein SACE_5102 3 None None None 134102749 Common - twin-arginine translocation pathway signal SACE_6314 52 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 134102207 Common slpD proteinase (secreted protein) SACE_5758 39 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134097972 Common - hypothetical protein SACE_1386 77 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 134102881 Common mtrA two-component response regulator SACE_6447 218 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 134100446 Common - second mannosyl transferase SACE_3911 172 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 134103026 Common ssp secreted subtilisin-like protease SACE_6595 100 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 134099809 Common - methyltransferase type 12 SACE_3270 91 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134100798 Common - hypothetical protein SACE_4265 50 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 134100013 Nonpathogen - tRNA/rRNA methyltransferase SACE_3475 2 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 134099994 Common - hypothetical protein SACE_3456 27 COG3662 COG3662, Uncharacterized protein conserved in bacteria Function unknown 134100153 Common ansB L-asparaginase II precursor SACE_3615 120 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 134101683 Common - transmembrane transport protein SACE_5175 98 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 134101779 Common pheT putative phenylalanyl-tRNA synthetase beta subunit SACE_5276 232 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 134102234 Common - oligopeptide ABC transporter, ATP-binding protein SACE_5786 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 134096764 Nonpathogen - hypothetical protein SACE_0147 1 None None None 134099666 Nonpathogen - hypothetical protein SACE_3124 1 None None None 134101969 Nonpathogen - hypothetical glycine-rich protein SACE_5513 1 COG3115 ZipA, Cell division protein Cell division and chromosome partitioning 134101533 Common - hypothetical protein SACE_5005 2 None None None 134103380 Common clpA clp protease ATP binding subunit SACE_6954 224 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 134103728 Common - transcriptional regulator, ArsR family SACE_7306 85 COG0640 ArsR, Predicted transcriptional regulators Transcription 134103177 Nonpathogen - hypothetical protein SACE_6747 1 None None None 134098574 Common - transposase for IS3518 SACE_2000 142 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 134098261 Common ctaC putative cytochrome c oxidase chain II SACE_1678 144 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 134099487 Common - putative zinc-containing dehydrogenase SACE_2945 194 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 134099119 Common - putative zinc-containing alcohol dehydrogenase (oxidoreductase) SACE_2564 117 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 134102967 Common - hydrolase, Ama/HipO/HyuC family SACE_6535 124 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 134100443 Common ilvX hypothetical protein SACE_3908 200 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 134098603 Common - PhnB protein SACE_2029 68 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 134099326 Common - transcriptional regulator, LysR family SACE_2781 190 COG0583 LysR, Transcriptional regulator Transcription 134102315 Common - MraZ protein SACE_5867 143 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 134099394 Common - probable acyl-CoA synthetase protein SACE_2851 137 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 134102965 Nonpathogen - hypothetical protein SACE_6533 1 None None None 134100657 Common - non-ribosomal peptide synthetase SACE_4124 10 None None None 134098317 Common - hypothetical protein SACE_1735 3 None None None 134103419 Common - hypothetical protein SACE_6993 25 COG5516 COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding General function prediction only 134100943 Nonpathogen - hypothetical protein SACE_4410 2 None None None 134101476 Common - Xaa-Pro dipeptidase family enzyme SACE_4946 81 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 134102485 Common lepB signal peptidase I SACE_6048 170 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 134100949 Common - pyridoxamine 5'-phosphate oxidase-related,FMN-binding protein SACE_4416 8 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 134099974 Nonpathogen - hypothetical protein SACE_3435 1 None None None 134096855 Common int integrase (recombinase) SACE_0239 46 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 134098503 Common - probable ABC transporter system, ATP-binding protein SACE_1928 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 134103511 Nonpathogen - hypothetical protein SACE_7087 1 None None None 134098985 Common pncB nicotinate phosphoribosyltransferase SACE_2423 129 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 134103515 Common - transcriptional regulator, XRE family SACE_7092 6 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 134101066 Common - NAD-dependent epimerase/dehydratase SACE_4533 9 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 134100902 Common - histidine kinase-response regulator hybrid protein SACE_4369 170 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 134099213 Nonpathogen - hypothetical protein SACE_2666 1 None None None 134102473 Common frr ribosome recycling factor SACE_6035 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 134097625 Common - hypothetical protein SACE_1029 16 None None None 134101394 Nonpathogen - hypothetical protein SACE_4864 1 None None None 134098371 Common plsC 1-acylglycerol-3-phosphate O-acyltransferase SACE_1791 121 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 134096732 Common mutM,fpg formamidopyrimidine-DNA glycosylase SACE_0114 180 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 134096997 Common - transcriptional regulator, TetR family SACE_0384 5 COG1309 AcrR, Transcriptional regulator Transcription 134097850 Common - aldehyde oxidase and xanthine dehydrogenase,molybdopterin binding SACE_1261 121 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 134100214 Common alkA1 putative ADA-like regulatory protein SACE_3676 82 COG2169 Ada, Adenosine deaminase Nucleotide transport and metabolism 134100257 Common - methyltransferase SACE_3721 45 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 134102109 Common - ABC transporter protein, ATP binding component SACE_5659 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 134102012 Common pimH integral membrane efflux protein SACE_5562 92 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134099458 Common - transcriptional regulator SACE_2916 84 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 134103776 Common pbp1A membrane carboxypeptidase (penicillin-binding protein) SACE_7356 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 134100370 Common - hypothetical protein SACE_3835 12 None None None 134097429 Common - aromatic acid transporter, MFS superfamily SACE_0824 44 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134103482 Common - hypothetical protein SACE_7057 52 COG2311 COG2311, Predicted membrane protein Function unknown 134100555 Common - molybdopterin dehydrogenase, FAD-binding protein SACE_4020 88 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 134096979 Common minD2 septum site determining protein SACE_0366 11 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 134097492 Nonpathogen - hypothetical protein SACE_0894 1 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 134099748 Common - hypothetical protein SACE_3209 12 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 134103443 Common - uncharacterized P-loop ATPase protein UPF0042 SACE_7018 124 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 134100253 Common - integral membrane transport protein SACE_3717 117 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 134102410 Common - cob(I)yrinic acid a,c-diamide adenosyltransferase SACE_5964 141 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 134101118 Common - probable sulfopyruvate decarboxylase alpha subunit SACE_4585 29 COG4032 COG4032, Predicted thiamine-pyrophosphate-binding protein General function prediction only 134097051 Common - CarD family transcriptional regulator SACE_0438 84 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 134097447 Common - hypothetical protein SACE_0842 20 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 134098467 Common - putative transmembrane sugar transport protein SACE_1891 144 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 134098504 Nonpathogen - hypothetical protein SACE_1929 1 None None None 134103581 Common - small multidrug resistance protein, SMR family SACE_7159 137 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 134099202 Common - transposase orfB, IS3 family SACE_2655 141 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 134098306 Common - secreted protein SACE_1724 28 COG4632 EpsL, Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Carbohydrate transport and metabolism 134103127 Nonpathogen - hypothetical protein SACE_6697 1 None None None 134100053 Common catJ 3-oxoadipate:succinyl-CoA transferase, B subunit SACE_3515 82 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 134100955 Common - integral membrane protein SACE_4422 35 COG2259 COG2259, Predicted membrane protein Function unknown 134102065 Common - transcriptional regulator, GntR family SACE_5615 100 COG1802 GntR, Transcriptional regulators Transcription 134096678 Nonpathogen - hypothetical protein SACE_0060 1 None None None 134102008 Common - hypothetical protein SACE_5558 14 None None None 134097203 Nonpathogen - hypothetical protein SACE_0593 1 None None None 134100104 Common fadE24 putative acyl-CoA dehydrogenase SACE_3566 149 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134099856 Common - protein of unknown function DUF574 SACE_3317 12 None None None 134101808 Common - transcriptional regulator, XRE family SACE_5305 6 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 134097769 Common - hypothetical protein SACE_1179 6 None None None 134100969 Nonpathogen - hypothetical protein SACE_4436 1 None None None 134096929 Common wblA transcriptional regulator SACE_0315 15 None None None 134098272 Common - hypothetical protein SACE_1689 231 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 134096680 Nonpathogen - hypothetical protein SACE_0062 1 None None None 134100833 Nonpathogen - hypothetical protein SACE_4300 5 None None None 134102570 Common cdo2 cysteine dioxygenase SACE_6133 9 COG5553 COG5553, Predicted metal-dependent enzyme of the double-stranded beta helix superfamily General function prediction only 134102732 Common thrB homoserine kinase SACE_6296 72 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 134101630 Common - transposase Tn3 SACE_5118 11 None None None 134100828 Common - putative transcriptional regulator SACE_4295 61 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 134101178 Common hisC2 putative histidinol-phosphate aminotransferase SACE_4645 216 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 134099343 Common - hypothetical protein SACE_2798 29 None None None 134099983 Common - short-chain dehydrogenase/reductase SDR SACE_3445 232 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134096672 Common - pyridoxal-dependent decarboxylase family protein, putative SACE_0054 101 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 134101131 Common - mandelate racemase/muconate lactonizing enzyme SACE_4598 137 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 134099533 Common - secreted glycosyl hydrolase SACE_2991 103 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 134101437 Common - terpene synthase, metal binding domain protein SACE_4907 12 None None None 134103675 Common - conserved membrane spanning protein SACE_7253 34 COG2311 COG2311, Predicted membrane protein Function unknown 134099503 Common - fructosyl-amino acid oxidase, putative SACE_2961 30 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 134101492 Nonpathogen - hypothetical protein SACE_4963 1 None None None 134102664 Common manA mannose-6-phosphate isomerase, class I SACE_6227 51 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 134101035 Common - formyltetrahydrofolate deformylase SACE_4502 218 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 134101567 Common - AfuB homolog SACE_5043 147 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 134102019 Common - putative phosphoheptose isomerase SACE_5569 161 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 134100356 Common - hypothetical protein SACE_3821 9 None None None 134100343 Common ctpI cation-transporting ATPase, E1-E2 family SACE_3808 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 134102406 Common cobJ putative precorrin methylase SACE_5960 74 COG2073 CbiG, Cobalamin biosynthesis protein CbiG Coenzyme metabolism 134098060 Common cysD sulfate adenylyltransferase subunit 2 SACE_1474 127 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 134098588 Common - putative branched-chain amino acid permease SACE_2014 81 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 134103778 Common - transcriptional regulator, PadR-like family SACE_7358 30 COG1695 COG1695, Predicted transcriptional regulators Transcription 134097687 Common nudC NADH pyrophosphatase SACE_1091 98 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 134097408 Common ksgA dimethyladenosine transferase SACE_0802 246 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 134103597 Common - secreted protein SACE_7175 24 None None None 134102097 Common - hypothetical protein SACE_5647 4 COG0529 CysC, Adenylylsulfate kinase and related kinases Inorganic ion transport and metabolism 134102379 Common - aminotransferase, class V SACE_5932 34 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 134098338 Common tpase1 transposase SACE_1756 97 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 134097396 Common - ABC transporter membrane protein SACE_0790 4 None None None 134102927 Nonpathogen - cell wall surface anchor family protein SACE_6494 2 COG5283 COG5283, Phage-related tail protein Function unknown 134099178 Common - modular polyketide synthase SACE_2630 210 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134103333 Common - glycosyl transferase, group 1 SACE_6905 173 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 134103664 Common fadE5 acyl-CoA dehydrogenase SACE_7242 141 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134103426 Nonpathogen - hypothetical protein SACE_7000 1 None None None 134103028 Common - possible dihydrofolate reductase SACE_6597 57 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 134098111 Common - 3-oxoacyl-(acyl-carrier-protein) synthase III SACE_1525 204 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 134100495 Common - alkyl-dihydroxyacetonephosphate synthase,putative SACE_3960 153 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 134099549 Nonpathogen - hypothetical protein SACE_3007 1 None None None 134103592 Common nha possible sodium/hydrogen antiporter SACE_7170 76 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 134101423 Common - probable transcriptional regulator, LuxR family SACE_4893 17 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134098638 Common - 3-dehydroquinate dehydratase, type II SACE_2068 169 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 134100011 Common - TetR-family transcriptional regulator SACE_3473 27 COG1309 AcrR, Transcriptional regulator Transcription 134101907 Common - enoyl-CoA hydratase SACE_5406 160 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 134100564 Common - putative ABC transporter ATP-binding protein SACE_4029 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 134097031 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase SACE_0418 49 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 134097460 Nonpathogen - hypothetical protein SACE_0855 3 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 134100431 Common - hypothetical protein SACE_3896 2 None None None 134097401 Common - triacylglycerol lipase precursor SACE_0795 12 None None None 134101233 Common proP proline/betaine transporter SACE_4701 165 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134097641 Common - ABC sugar transporter, permease component SACE_1045 86 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 134102102 Common - integral membrane protein SACE_5652 11 None None None 134098194 Common nadE glutamine-dependent NAD(+) synthetase SACE_1610 221 COG0171 NadE, NAD synthase Coenzyme metabolism 134102140 Nonpathogen - hypothetical protein SACE_5691 2 None None None 134100229 Common pyrE orotate phosphoribosyltransferase SACE_3691 26 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 134101824 Common - putative transposase SACE_5321 51 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 134100033 Common leuB1 3-isopropylmalate dehydrogenase SACE_3495 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 134101274 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase SACE_4742 152 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134102370 Common - phosphoesterase, RecJ-like protein SACE_5923 77 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 134096642 Common - 2-nitropropane dioxygenase, NPD SACE_0024 20 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 134098571 Common - aldehyde dehydrogenase, NAD-dependent SACE_1997 177 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 134099209 Common - methyltransferase type 11 SACE_2662 178 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134101725 Common - HAD-superfamily hydrolase subfamily IA, variant 3 SACE_5220 125 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 134101171 Common - xylose isomerase domain protein TIM barrel SACE_4638 41 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 134101757 Common - hypothetical protein SACE_5253 18 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 134099266 Common - hypothetical protein SACE_2721 4 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 134103713 Common dapE peptidase, M20/M25/M40 family SACE_7291 93 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 134097435 Nonpathogen - PE_PGRS family protein SACE_0830 1 None None None 134101086 Common - putative oligopeptide ABC transporter ATP-binding protein SACE_4553 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 134101158 Nonpathogen - hypothetical protein SACE_4625 1 None None None 134103327 Common nuoD NADH dehydrogenase subunit D SACE_6899 192 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 134098497 Common ackA acetate/propionate kinase SACE_1922 162 COG0282 ackA, Acetate kinase Energy production and conversion 134102896 Common - integral membrane regulatory protein SACE_6463 17 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 134103730 Common - hypothetical protein SACE_7308 23 None None None 134100333 Common - SIR2 family transcriptional regulator SACE_3798 152 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 134096824 Common - daunorubicin resistance ABC transporter ATPase subunit SACE_0207 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 134101091 Common serA D-3-phosphoglycerate dehydrogenase SACE_4558 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 134101972 Common - hypothetical protein SACE_5516 8 None None None 134098654 Common carB carbamoyl-phosphate synthase large subunit SACE_2083 234 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 134100903 Common - sensory box protein SACE_4370 184 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 134099368 Common - hypothetical protein SACE_2825 18 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 134103627 Common - hypothetical protein SACE_7205 53 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 134099234 Common - hypothetical protein SACE_2688 10 None None None 134098029 Common - possible transporter, DMT superfamily SACE_1443 42 None None None 134102262 Common cypA cytochrome P450-like enzyme SACE_5814 93 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134100319 Common - hypothetical protein SACE_3784 9 None None None 134098737 Common - regulatory protein, MarR SACE_2167 11 COG1510 COG1510, Predicted transcriptional regulators Transcription 134101163 Common - LacI-type transcriptional regulator SACE_4630 127 COG1609 PurR, Transcriptional regulators Transcription 134099479 Nonpathogen - hypothetical protein SACE_2937 5 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 134099432 Common nysRI LuxR-family transcriptional regulator SACE_2890 14 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134102626 Common ebrB multidrug resistance efflux protein SACE_6189 178 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134103228 Nonpathogen - hypothetical protein SACE_6800 1 COG4872 COG4872, Predicted membrane protein Function unknown 134098626 Nonpathogen - hypothetical protein SACE_2056 1 None None None 134102162 Common dacC,pbp penicillin binding protein SACE_5713 110 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 134097022 Common lysS lysyl-tRNA synthetase class II SACE_0409 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 134097111 Common glmS glucosamine-fructose-6-phosphate aminotransferase SACE_0498 231 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 134098368 Common - probable rRNA/tRNA methylase SACE_1788 87 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 134102289 Common - putative ABC transporter sugar-binding protein SACE_5841 78 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 134097330 Common eryAIII EryAIII Erythromycin polyketide synthase modules 5 and 6 SACE_0724 210 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134100881 Common lacI transcriptional repressor of the lac operon SACE_4348 126 COG1609 PurR, Transcriptional regulators Transcription 134101262 Nonpathogen - hypothetical protein SACE_4730 1 None None None 134100237 Common - hypothetical protein SACE_3699 9 None None None 134098364 Common fumB fumarate hydratase class I SACE_1784 147 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 134097372 Common moaB putative molybdenum cofactor biosynthesis protein SACE_0766 41 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 134102780 Common - hypothetical protein SACE_6346 90 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 134100931 Common - citryl-CoA lyase SACE_4398 104 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 134096943 Common - transcriptional regulator, Crp/Fnr family SACE_0329 158 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 134098479 Common - alpha/beta hydrolase SACE_1904 159 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134102036 Common - Zn-binding alcohol dehydrogenase SACE_5586 208 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 134103453 Common - hypothetical protein SACE_7028 8 None None None 134103493 Common - short-chain dehydrogenase/reductase SDR SACE_7068 235 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 134098556 Common - cholesterol esterase SACE_1982 6 None None None 134101991 Common - hypothetical protein with pantoate--beta-alanine ligase and Hydroxymethylglutaryl-coenzyme A reductase domains SACE_5541 209 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 134102123 Nonpathogen - hypothetical protein SACE_5673 3 None None None 134103523 Common mshD acetyltransferase SACE_7100 24 COG0456 RimI, Acetyltransferases General function prediction only 134102776 Common - amidohydrolase domain protein SACE_6342 112 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 134096896 Common lysC,ask aspartate kinase SACE_0282 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 134098541 Common - possible protocatechuate dioxygenase SACE_1967 29 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 134101692 Common - acetyltransferase, including N-acetylase of ribosomal protein SACE_5184 118 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 134099415 Common - glutathione S-transferase SACE_2873 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 134099873 Nonpathogen - hypothetical protein SACE_3334 1 None None None 134099832 Common - hypothetical protein SACE_3293 111 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 134103095 Common purN phosphoribosylglycinamide formyltransferase SACE_6665 226 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 134101842 Common - 6-phosphogluconate dehydrogenase, NAD-binding SACE_5340 89 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 134098562 Common - universal stress protein UspA SACE_1988 34 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 134096653 Common - rhomboid-like protein SACE_0035 143 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 134102577 Common ppk polyphosphate kinase SACE_6140 162 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 134100203 Common - hypothetical protein SACE_3665 39 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 134099756 Common - methyltransferase SACE_3217 93 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134103649 Common - MerR-family transcriptional regulator SACE_7227 5 COG0789 SoxR, Predicted transcriptional regulators Transcription 134097777 Common ctaD cytochrome c oxidase subunit I SACE_1187 169 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 134102087 Nonpathogen - hypothetical protein SACE_5637 2 None None None 134100520 Common - short-chain dehydrogenase/reductase SDR SACE_3985 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 134099569 Common - gamma-aminobutyrate permease SACE_3027 140 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 134102343 Nonpathogen - hypothetical protein SACE_5896 1 None None None 134100573 Common fadD long-chain acyl-CoA synthetase SACE_4038 104 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134102619 Common - methionine synthase, vitamin-B12 independent SACE_6182 15 None None None 134096922 Common - hypothetical protein SACE_0308 14 None None None 134102308 Common - mandelate racemase/muconate lactonizing enzyme SACE_5860 102 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 134097164 Common - nitrate ABC transporter, ATP-binding protein,putative SACE_0553 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 134097855 Common - Orn/DAP/Arg decarboxylase 2 SACE_1266 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 134103167 Common pbuX2 xanthine/uracil permease SACE_6737 118 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 134096815 Common embC arabinosyl transferase SACE_0198 5 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 134099005 Common uspA3 universal stress protein family SACE_2443 24 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 134099440 Common - hypothetical protein SACE_2898 94 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 134099590 Common - putative type I polyketide synthase SACE_3048 55 COG3320 COG3320, Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 134103423 Nonpathogen - hypothetical protein SACE_6997 2 None None None 134103617 Common ytrA GntR family transcriptional regulator SACE_7195 37 COG1725 COG1725, Predicted transcriptional regulators Transcription 134101668 Common - short-chain dehydrogenase/reductase SDR SACE_5160 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134101151 Common - aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead SACE_4618 118 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 134099094 Common - hypothetical protein SACE_2539 25 None None None 134098470 Common - transcriptional regulator, XRE family SACE_1895 6 COG1396 HipB, Predicted transcriptional regulators Transcription 134099684 Common mdlC benzoylformate decarboxylase SACE_3142 220 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 134103350 Nonpathogen - hypothetical protein SACE_6923 1 None None None 134098409 Common - putative ribonuclease D (partial match) SACE_1832 110 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 134101651 Common - arsenical resistance protein/arsenate reductase SACE_5142 125 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 134098102 Nonpathogen - hypothetical protein SACE_1516 1 None None None 134101468 Common ydfJ putative membrane transport protein SACE_4938 143 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 134100764 Nonpathogen - hypothetical protein SACE_4231 1 None None None 134102843 Common - putative ABC transport system substrate binding protein SACE_6409 87 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 134098177 Nonpathogen - hypothetical protein SACE_1593 1 None None None 134103283 Nonpathogen - hypothetical protein SACE_6855 4 None None None 134103404 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase SACE_6978 129 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 134099271 Common - oxidoreductase, molybdopterin binding SACE_2726 82 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 134098213 Common - putative transcriptional regulator SACE_1630 121 COG0583 LysR, Transcriptional regulator Transcription 134098691 Common ribG diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase SACE_2121 227 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 134098714 Common pgk phosphoglycerate kinase SACE_2144 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 134099093 Nonpathogen - hypothetical protein SACE_2538 1 COG2391 COG2391, Predicted transporter component General function prediction only 134101117 Common - possible sulfopyruvate decarboxylase beta subunit SACE_4584 30 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 134101948 Common - putative DNA-binding protein SACE_5450 131 COG1278 CspC, Cold shock proteins Transcription 134102421 Common - Raf kinase inhibitor homologous protein SACE_5975 119 COG1881 COG1881, Phospholipid-binding protein General function prediction only 134103554 Nonpathogen - LuxR-family transcriptional regulator SACE_7132 8 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134099695 Common accC3 biotin carboxylase SACE_3154 232 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 134102254 Common - hypothetical protein SACE_5806 3 None None None 134102428 Nonpathogen - hypothetical protein SACE_5984 1 None None None 134096725 Common msrA peptide methionine sulfoxide reductase SACE_0107 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 134100176 Common - transposase SACE_3638 34 None None None 134097118 Common ThiS thiamine-biosynthesis SACE_0507 19 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 134097257 Common cscK ribokinase:carbohydrate kinase, PfkB SACE_0647 140 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 134097036 Common - multidrug ABC transporter permease SACE_0423 95 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 134100074 Common - stress-inducible protein SACE_3536 62 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 134101531 Common - two component transcriptional regulator, LuxR family SACE_5003 170 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134102226 Common - histidinol-phosphate aminotransferase SACE_5777 232 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 134097032 Nonpathogen - putative transcriptional regulator SACE_0419 2 COG1846 MarR, Transcriptional regulators Transcription 134100121 Common - TetR-family transcriptional regulator SACE_3583 23 COG1309 AcrR, Transcriptional regulator Transcription 134099865 Common tktA2 transketolase SACE_3326 231 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 134097278 Nonpathogen - hypothetical protein SACE_0669 1 None None None 134101559 Common - transposase, IS4 SACE_5035 30 COG5659 COG5659, FOG: Transposase DNA replication, recombination, and repair 134102550 Common - probable aminopeptidase SACE_6113 11 COG2234 Iap, Predicted aminopeptidases General function prediction only 134096637 Common - AMP-dependent synthetase and ligase SACE_0019 21 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134100667 Common - hypothetical protein SACE_4134 32 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 134101711 Common - aminopeptidase (secreted protein) SACE_5205 60 COG2234 Iap, Predicted aminopeptidases General function prediction only 134099244 Common - putative regulatory protein SACE_2698 22 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 134102155 Nonpathogen - hypothetical protein SACE_5706 1 None None None 134096827 Nonpathogen - hypothetical protein SACE_0210 1 None None None 134099814 Common - transcriptional regulator, LacI family SACE_3275 129 COG1609 PurR, Transcriptional regulators Transcription 134101499 Common - transposase, IS4 SACE_4971 43 None None None 134096884 Nonpathogen - hypothetical protein SACE_0269 1 None None None 134101772 Common - putative transposase SACE_5268 68 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 134099672 Common - ATP-dependent helicase HrpB SACE_3130 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 134097215 Nonpathogen - hypothetical protein SACE_0605 1 None None None 134100086 Common - putative phenylacetic acid degradation NADH oxidoreductase SACE_3548 135 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 134099025 Nonpathogen - hypothetical protein SACE_2463 6 None None None 134098822 Common - putative glycerophosphatase SACE_2253 16 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 134099602 Nonpathogen - hypothetical protein SACE_3060 1 None None None 134100970 Common - hydrolase SACE_4437 96 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 134098423 Common - ROK-family transcriptional regulator SACE_1847 74 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 134102518 Nonpathogen - hypothetical protein SACE_6081 1 None None None 134100111 Nonpathogen - hypothetical protein SACE_3573 1 None None None 134098228 Nonpathogen - hypothetical protein SACE_1645 1 None None None 134102196 Nonpathogen - hypothetical protein SACE_5747 1 None None None 134100739 Nonpathogen - hypothetical protein SACE_4206 5 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 134101184 Common tauD taurine dioxygenase, 2-oxoglutarate-dependent SACE_4651 47 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 134097742 Common cvnB11 hypothetical protein SACE_1150 10 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 134101041 Common - formate dehydrogenase accessory protein SACE_4508 135 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 134100584 Common - membrane dipeptidase SACE_4049 102 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 134101260 Common - ATP-binding region, ATPase-like SACE_4728 104 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 134098820 Common prcB 20S proteasome beta-subunit precursor SACE_2251 45 COG0638 PRE1, 20S proteasome, alpha and beta subunits Posttranslational modification, protein turnover, chaperones 134097661 Common - transcriptional regulator (TetR/AcrR family) SACE_1065 23 COG1309 AcrR, Transcriptional regulator Transcription 134099558 Common - SyrP-like protein SACE_3016 22 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 134102588 Common leuA2 putative alpha-isopropylmalate/homocitrate synthase family transferase SACE_6151 187 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 134100289 Common acnA1 aconitate hydratase SACE_3754 223 COG1048 AcnA, Aconitase A Energy production and conversion 134097907 Nonpathogen - hypothetical protein SACE_1320 1 None None None 134101014 Common - transcriptional regulator, ArsR family SACE_4481 43 COG0640 ArsR, Predicted transcriptional regulators Transcription 134097436 Nonpathogen - hypothetical protein SACE_0831 1 None None None 134098760 Common - hypothetical protein SACE_2190 18 COG4821 COG4821, Uncharacterized protein containing SIS (Sugar ISomerase) phosphosugar binding domain General function prediction only 134101241 Common - hypothetical protein SACE_4709 2 COG4189 COG4189, Predicted transcriptional regulator Transcription 134098548 Nonpathogen - hypothetical protein SACE_1974 1 None None None 134102883 Common - OsmC-like protein SACE_6449 42 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 134099944 Common - TetR-family transcriptional regulator SACE_3405 47 COG1309 AcrR, Transcriptional regulator Transcription 134099059 Common - integral membrane protein, MmpL family SACE_2502 15 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 134102657 Common - protein of unknown function DUF77 SACE_6220 23 COG0011 COG0011, Uncharacterized conserved protein Function unknown 134103182 Common - protein of unknown function DUF1365 SACE_6752 59 COG3496 COG3496, Uncharacterized conserved protein Function unknown 134098088 Common dgt deoxyguanosinetriphosphate triphosphohydrolase-like protein SACE_1502 160 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 134096755 Common sdrB differentiation regulon (IclR-family transcriptional regulator) SACE_0137 79 COG1414 IclR, Transcriptional regulator Transcription 134097574 Common bioD dithiobiotin synthetase SACE_0978 7 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 134103277 Common - hypothetical protein SACE_6849 2 None None None 134103634 Common - cytosine/purines/uracil/thiamine/allantoin permease family protein SACE_7212 47 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 134099631 Common - SWIM zinc finger domain protein SACE_3089 38 COG4279 COG4279, Uncharacterized conserved protein Function unknown 134100960 Common mug G/U mismatch-specific DNA glycosylase SACE_4427 30 COG3663 Mug, G:T/U mismatch-specific DNA glycosylase DNA replication, recombination, and repair 134101225 Common - putative transcriptional regulator SACE_4693 10 COG2345 COG2345, Predicted transcriptional regulator Transcription 134098235 Common - oxidoreductase, aldo/keto reductase family SACE_1652 198 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 134099302 Common - 2,4-dienoyl-CoA reductase SACE_2757 177 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 134100464 Common lipB,yfiP lipase SACE_3929 42 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 134101371 Common - transport protein, MFS superfamily SACE_4842 90 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 134099038 Common - transposase SACE_2478 9 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 134098618 Common - recombination factor protein RarA SACE_2048 208 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 134101733 Nonpathogen - hypothetical protein SACE_5229 1 None None None 134097761 Common - possible succinate dehydrogenase SACE_1169 10 None None None 134098730 Common tkt transketolase SACE_2160 221 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 134098094 Common tam trans-aconitate methyltransferase SACE_1508 53 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 134102507 Nonpathogen - hypothetical protein SACE_6070 1 None None None 134102555 Common pyc pyruvate carboxylase SACE_6118 238 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 134099445 Common - universal stress protein SACE_2903 16 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 134097630 Common htrA possinble serine protease SACE_1034 220 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 134101770 Nonpathogen - hypothetical protein SACE_5266 2 None None None 134103396 Common - hypothetical protein SACE_6970 10 None None None 134100213 Common - GCN5-related N-acetyltransferase SACE_3675 3 COG2153 ElaA, Predicted acyltransferase General function prediction only 134102176 Nonpathogen - hypothetical protein SACE_5727 1 None None None 134098241 Common amlB secreted alpha-amylase SACE_1658 29 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 134102353 Common - GCN5-related N-acetyltransferase SACE_5906 17 COG3393 COG3393, Predicted acetyltransferase General function prediction only 134098685 Common codA cytosine deaminase SACE_2115 102 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 134100008 Nonpathogen - dual specificity protein phosphatase SACE_3470 6 COG2453 CDC14, Predicted protein-tyrosine phosphatase Signal transduction mechanisms 134102706 Common murA,murZ UDP-N-acetylglucosamine 1-carboxyvinyltransferase SACE_6270 221 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 134099229 Common - hypothetical protein SACE_2683 8 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 134100028 Common - sensor histidine kinase/response regulator SACE_3490 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 134097522 Common - extracellular solute-binding protein, family 1 SACE_0924 68 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 134099887 Common - transcriptional regulator, XRE family SACE_3348 6 None None None 134096845 Common - chloramphenicol resistance protein SACE_0228 194 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134101781 Common tsnR 23S ribosomal RNA methyltransferase SACE_5278 111 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 134102932 Common hmgL hydroxymethylglutaryl-CoA lyase SACE_6499 177 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 134103101 Nonpathogen - hypothetical protein SACE_6671 1 None None None 134100888 Common - ArsR-family transcriptional regulator SACE_4355 45 COG0640 ArsR, Predicted transcriptional regulators Transcription 134097584 Common - acetyltransferase (GNAT) family protein SACE_0988 42 None None None 134101915 Common - hypothetical protein SACE_5414 32 COG2312 COG2312, Erythromycin esterase homolog General function prediction only 134102108 Common rbsR putative LacI-family transcriptional regulator SACE_5658 128 COG1609 PurR, Transcriptional regulators Transcription 134097531 Common - secreted trypsin-like serine protease SACE_0933 30 COG5640 COG5640, Secreted trypsin-like serine protease Posttranslational modification, protein turnover, chaperones 134098833 Common - hypothetical protein SACE_2264 75 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 134102822 Common - hypothetical protein SACE_6388 8 None None None 134100360 Common - sulfatase modifying factor SACE_3825 106 COG1262 COG1262, Uncharacterized conserved protein Function unknown 134096728 Common chb secreted chitin binding protein SACE_0110 28 COG3397 COG3397, Uncharacterized protein conserved in bacteria Function unknown 134098356 Common galK galactokinase SACE_1775 92 COG0153 GalK, Galactokinase Carbohydrate transport and metabolism 134101258 Nonpathogen - hypothetical protein SACE_4726 1 None None None 134101372 Common - phenazine biosynthesis PhzC/PhzF protein SACE_4843 107 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 134097637 Common - possible MutT/NUDIX family protein SACE_1041 38 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 134099846 Common - secreted protein SACE_3307 14 None None None 134099960 Common - hypothetical protein SACE_3421 29 COG3211 PhoX, Predicted phosphatase General function prediction only 134102043 Common - hypothetical protein SACE_5593 6 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 134098860 Common glpQ4 putative glycerophosphoryl diester phosphodiesterase SACE_2292 91 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 134103142 Common - two-component system response regulator SACE_6712 151 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134097673 Common - possible ATP-dependent DNA helicase SACE_1077 163 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 134097725 Common - hypothetical protein SACE_1130 2 None None None 134100450 Common - NAD-dependent epimerase/dehydratase SACE_3915 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 134097943 Nonpathogen - hypothetical protein SACE_1357 1 None None None 134099618 Common - hydrogenase nickel incorporation protein HypB SACE_3076 121 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 134099639 Nonpathogen - hypothetical protein SACE_3097 1 None None None 134101382 Common adh1 alcohol dehydrogenase SACE_4852 78 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 134103102 Common - metalloendopeptidase-like membrane protein SACE_6672 192 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 134101552 Common - TetR-family transcriptional regulator SACE_5028 20 COG1309 AcrR, Transcriptional regulator Transcription 134097275 Nonpathogen - hypothetical protein SACE_0666 1 None None None 134102561 Nonpathogen - hypothetical protein SACE_6124 2 None None None 134103110 Common - LysR-family transcriptional regulator SACE_6680 94 COG0583 LysR, Transcriptional regulator Transcription 134101193 Common - transcriptional regulator, LacI family SACE_4660 125 COG1609 PurR, Transcriptional regulators Transcription 134099169 Common - modular polyketide synthase SACE_2620 209 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134101883 Common fabG3 putative 3-oxoacyl-[acyl-carrier protein] reductase SACE_5381 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134103535 Common - ferric uptake regulator, FUR family SACE_7112 45 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 134102742 Nonpathogen - hypothetical protein SACE_6307 1 None None None 134103735 Common - activator of HSP90 ATPase 1 family protein SACE_7313 45 COG3832 COG3832, Uncharacterized conserved protein Function unknown 134103792 Common - acyl-CoA oxidase SACE_7372 131 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134100189 Common tnpA Tn5045 transposase SACE_3651 53 COG4644 COG4644, Transposase and inactivated derivatives, TnpA family DNA replication, recombination, and repair 134103171 Common - hypothetical protein SACE_6741 4 None None None 134101988 Common fabF 3-oxoacyl-[acyl-carrier-protein] synthase SACE_5538 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134102713 Nonpathogen - hypothetical protein SACE_6277 3 None None None 134096831 Common - cationic amino acid transport protein SACE_0214 151 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 134098407 Common - possible transcriptional regulator, AraC family SACE_1830 20 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 134101297 Common dak putative dihydroxyacetone (glycerone) kinase protein SACE_4765 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 134100196 Common - possible transcriptional regulator, MerR family SACE_3658 11 COG0789 SoxR, Predicted transcriptional regulators Transcription 134101138 Common serA D-3-phosphoglycerate dehydrogenase SACE_4605 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 134103344 Common menA 1,4-dihydroxy-2-naphthoate octaprenyltransferase SACE_6917 109 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 134103642 Common - iron-sulphur-binding reductase SACE_7220 101 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 134097934 Common blaB3 metallo-beta-lactamase SACE_1347 44 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 134096749 Common arcA arginine deiminase SACE_0131 57 COG2235 ArcA, Arginine deiminase Amino acid transport and metabolism 134096791 Common - transcriptional regulator, PadR-like family SACE_0174 43 COG1695 COG1695, Predicted transcriptional regulators Transcription 134101157 Nonpathogen - hypothetical protein SACE_4624 1 None None None 134097360 Common rpmB 50S ribosomal protein L28 SACE_0754 147 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 134100131 Nonpathogen - hypothetical protein SACE_3593 1 None None None 134103069 Common - hypothetical protein SACE_6639 8 None None None 134103178 Nonpathogen - hypothetical protein SACE_6748 1 None None None 134096875 Common - oligopeptide ABC transporter ATP-binding protein SACE_0260 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 134101406 Common gctB glutaconate CoA transferase subunit B SACE_4876 59 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 134100263 Common - putative transposase, IS891/IS1136/IS1341 SACE_3728 72 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 134099152 Nonpathogen - hypothetical protein SACE_2597 1 None None None 134102718 Common atpA F0F1 ATP synthase subunit alpha SACE_6282 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 134100541 Common paaH2 3-hydroxybutyryl-CoA dehydrogenase SACE_4006 161 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 134097469 Common pkn6 serine/threonine protein kinase SACE_0867 154 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 134103410 Common - hypothetical protein SACE_6984 6 None None None 134099372 Common aspA aspartate ammonia-lyase SACE_2829 231 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 134101183 Common - O-methyltransferase SACE_4650 47 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134101205 Common - hypothetical protein SACE_4673 236 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 134097885 Common - probable transcriptional activator (regulator) protein, TenA family SACE_1298 75 COG0819 TenA, Putative transcription activator Transcription 134099965 Common - short-chain dehydrogenase/reductase SDR SACE_3426 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134100730 Common sig1 RNA polymerase sigma factor SACE_4197 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 134098285 Common - hypothetical protein SACE_1703 9 None None None 134100758 Common - L-carnitine dehydratase/bile acid-inducible protein F SACE_4225 109 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 134100002 Common - hypothetical protein SACE_3464 35 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 134097681 Nonpathogen - hypothetical protein SACE_1085 1 None None None 134100562 Nonpathogen - hypothetical protein SACE_4027 1 None None None 134100850 Common - acetyltransferase SACE_4317 15 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 134098882 Nonpathogen - hypothetical protein SACE_2317 1 None None None 134100426 Common - hypothetical protein SACE_3891 7 COG4270 COG4270, Predicted membrane protein Function unknown 134101582 Common - alpha-glucosidase, family 31 of glycosyl hydrolase SACE_5058 82 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 134103198 Common - hypothetical protein SACE_6769 6 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 134099137 Common - mandelate racemase/muconate lactonizing enzyme SACE_2582 119 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 134099157 Common - SAM-dependent O-methyltransferase SACE_2602 45 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134099649 Nonpathogen - hypothetical protein SACE_3107 3 None None None 134097989 Common - putative Fe-S oxidoreductase SACE_1403 64 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 134098875 Nonpathogen - hypothetical protein SACE_2310 2 None None None 134100455 Common - UDP-glucose/GDP-mannose dehydrogenase SACE_3920 206 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 134102643 Common - methyltransferase type 11 SACE_6206 170 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134103465 Common - putative TetR family transcriptional regulator (partial match) SACE_7040 78 COG1309 AcrR, Transcriptional regulator Transcription 134101454 Common - hypothetical protein SACE_4924 9 None None None 134098067 Common sdrD protein involving differentiation SACE_1481 118 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 134102241 Common - metabolite transporter, MFS superfamily SACE_5793 122 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 134100048 Common pcaC 4-carboxymuconolactone decarboxylase SACE_3510 89 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 134098679 Common - hypothetical protein SACE_2109 9 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 134102075 Common - hypothetical protein SACE_5625 6 None None None 134098995 Common - NADH-quinone oxidoreductase chain F SACE_2433 160 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 134098865 Nonpathogen - hypothetical protein SACE_2299 1 None None None 134102174 Nonpathogen - hypothetical protein SACE_5725 1 None None None 134100267 Nonpathogen - hypothetical protein SACE_3732 1 None None None 134102675 Common - methylmalonyl-CoA epimerase SACE_6238 90 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 134103539 Common - L-asparaginase II SACE_7116 46 COG4448 AnsA, L-asparaginase II Amino acid transport and metabolism 134099426 Common ribA GTP cyclohydrolase II SACE_2884 185 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 134100180 Nonpathogen - hypothetical protein SACE_3642 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 134101540 Common - animal haem peroxidase SACE_5012 11 None None None 134100611 Common sidF ferrichrome ABC transporter substrate-binding protein SACE_4076 7 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 134100924 Common fprB ferredoxin--NADP+ reductase SACE_4391 204 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 134103368 Nonpathogen - hypothetical protein SACE_6941 1 None None None 134098772 Common - carboxylpeptidase SACE_2202 78 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 134100942 Common - possible transcriptional regulatory protein (possibly ArsR-family) SACE_4409 94 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 134098803 Nonpathogen - hypothetical protein SACE_2234 1 None None None 134103529 Common cysA3 thiosulfate sulfurtransferase SACE_7106 144 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 134103210 Common rplM 50S ribosomal protein L13 SACE_6781 241 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 134096630 Common - TetR-family transcriptional regulator SACE_0012 35 COG1309 AcrR, Transcriptional regulator Transcription 134098644 Common ogt3 putative methylated-DNA--protein-cysteine S-methyltransferase SACE_2073 205 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 134098151 Common kdgR transcriptional regulator, IclR family SACE_1565 123 COG1414 IclR, Transcriptional regulator Transcription 134102433 Common map methionine aminopeptidase SACE_5989 240 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 134101253 Nonpathogen - hypothetical protein SACE_4721 6 COG4274 COG4274, Uncharacterized conserved protein Function unknown 134098269 Common - probable ubiquinol-cytochrome c reductase iron-sulfur subunit SACE_1686 32 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 134097508 Nonpathogen - hypothetical protein SACE_0910 1 None None None 134097839 Common - hypothetical protein SACE_1250 13 None None None 134099123 Nonpathogen - hypothetical protein SACE_2568 1 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134103314 Common - probable transcriptional regulatory protein (probably AsnC-family) SACE_6886 151 COG1522 Lrp, Transcriptional regulators Transcription 134102867 Common - putative bacteriophage protein SACE_6433 108 COG2135 COG2135, Uncharacterized conserved protein Function unknown 134096712 Common - oxidoreductase, aldo/keto reductase family SACE_0094 199 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 134098974 Common - high-affinity iron transporter SACE_2412 89 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 134100715 Nonpathogen - hypothetical protein SACE_4182 1 None None None 134102526 Common kdpA potassium-transporting ATPase subunit A SACE_6089 96 COG2060 KdpA, K+-transporting ATPase, A chain Inorganic ion transport and metabolism 134099882 Common resD two-component response regulator SACE_3343 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 134098973 Nonpathogen - hypothetical protein SACE_2411 1 None None None 134099033 Common - hypothetical protein SACE_2472 24 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 134099331 Common ribA 34-dihydroxy-2-butanone 4-phosphate synthase SACE_2786 226 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 134099783 Common - TetR-family transcriptional regulator SACE_3244 82 COG1309 AcrR, Transcriptional regulator Transcription 134103157 Common - allantoinase SACE_6727 210 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 134102783 Common metE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase SACE_6349 141 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 134101026 Common soxD sarcosine oxidase, delta chain SACE_4493 37 COG4311 SoxD, Sarcosine oxidase delta subunit Amino acid transport and metabolism 134102248 Common - CAAX amino terminal protease family SACE_5800 15 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 134096670 Common phoD phosphodiesterase/alkaline phosphatase D SACE_0052 56 COG3540 PhoD, Phosphodiesterase/alkaline phosphatase D Inorganic ion transport and metabolism 134100585 Common - hypothetical protein SACE_4050 8 None None None 134100091 Common - hypothetical protein SACE_3553 11 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 134097214 Common ilvB acetolactate synthase large subunit SACE_0604 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 134097945 Common tig putative cell division trigger factor SACE_1359 211 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 134099069 Common - MFS sugar transporter SACE_2512 185 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134100440 Common - hydrolase, alpha/beta fold family SACE_3905 98 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134097067 Common - sugar ABC transporter, ATP-binding protein SACE_0454 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 134101025 Common soxA sarcosine oxidase (alpha subunit) oxidoreductase protein SACE_4492 180 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 134099573 Common - hypothetical protein SACE_3031 2 None None None 134103726 Common - acetyl-CoA acetyltransferase SACE_7304 169 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 134099967 Common - TetR-family transcriptional regulator SACE_3428 41 COG1309 AcrR, Transcriptional regulator Transcription 134103507 Nonpathogen - drug/metabolite transporter (DMT) superfamily protein SACE_7083 4 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 134099830 Common - possible transcriptional regulator, ROK family SACE_3291 157 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 134098252 Common - hypothetical protein SACE_1669 110 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 134099478 Nonpathogen - hypothetical protein SACE_2936 1 None None None 134096960 Common - probable transcriptional regulator, LysR family SACE_0346 190 COG0583 LysR, Transcriptional regulator Transcription 134103166 Common - urate oxidase SACE_6736 14 COG3648 COG3648, Uricase (urate oxidase) Secondary metabolites biosynthesis, transport, and catabolism 134097268 Common - TetR-family transcriptional regulator SACE_0659 11 COG1309 AcrR, Transcriptional regulator Transcription 134101547 Common - hypothetical protein SACE_5023 21 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 134101776 Nonpathogen - hypothetical protein SACE_5273 1 None None None 134097141 Common - hypothetical protein SACE_0530 27 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 134097564 Common gvpS1 gas vesicle synthesis protein SACE_0968 12 None None None 134097412 Common ispE 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase SACE_0807 188 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 134101219 Common - hypothetical protein SACE_4687 7 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 134102812 Common gcvH glycine cleavage system H protein SACE_6378 187 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 134101859 Nonpathogen - hypothetical protein SACE_5357 2 None None None 134101122 Common - acyl-CoA dehydrogenase SACE_4589 166 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134102594 Common ilvC ketol-acid reductoisomerase SACE_6157 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 134096878 Common - probable amino acid metabolite transport protein SACE_0263 101 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 134102362 Common rpsO 30S ribosomal protein S15 SACE_5915 214 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 134102539 Common - protein of unknown function DUF177 SACE_6102 18 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 134097291 Common - probable transcriptional regulator, AraC family SACE_0684 114 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 134101810 Common chlB3 3-oxoacyl-ACP synthase III SACE_5307 29 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 134103044 Common - putative type I restriction system adenine methylase SACE_6614 109 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 134099628 Common - probable transcriptional regulator, ArcR family SACE_3086 14 COG1309 AcrR, Transcriptional regulator Transcription 134096629 Nonpathogen - hypothetical protein SACE_0011 1 None None None 134101031 Common folD putative methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase SACE_4498 223 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 134099712 Common - putative methyltransferase SACE_3172 32 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134100981 Nonpathogen - hypothetical protein SACE_4448 1 None None None 134103546 Common purM phosphoribosylaminoimidazole synthetase SACE_7124 231 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 134097093 Nonpathogen - hypothetical protein SACE_0479 1 None None None 134101535 Common - hypothetical protein SACE_5007 4 COG2234 Iap, Predicted aminopeptidases General function prediction only 134102847 Common - methyltransferases-like SACE_6413 16 COG1568 COG1568, Predicted methyltransferases General function prediction only 134102984 Common - phosphate binding protein (secreted protein) SACE_6552 64 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 134101962 Nonpathogen - hypothetical protein SACE_5480 2 None None None 134103145 Common groES 10 kD chaperonin cpn10 SACE_6715 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 134097774 Common - putative acyl coenzyme A thioester hydrolase SACE_1184 22 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 134097716 Common - phage integrase SACE_1121 111 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 134101838 Common - putative methyltransferase SACE_5336 94 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134101944 Common - hypothetical protein SACE_5446 60 COG3899 COG3899, Predicted ATPase General function prediction only 134099545 Common - FMN-dependent monooxygenase SACE_3003 45 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 134097205 Common - hypothetical protein SACE_0595 4 None None None 134099077 Common - transposase, IS4 SACE_2521 46 None None None 134102941 Common - sodium:dicarboxylate symporter SACE_6508 162 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 134101985 Common - secreted protein SACE_5534 17 COG3868 COG3868, Uncharacterized conserved protein Function unknown 134099594 Common - medium-chain acyl-CoA ligase SACE_3052 222 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134098594 Common - hypothetical protein SACE_2020 8 None None None 134099917 Common - major facilitator superfamily (MFS) transporter SACE_3378 145 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134100953 Common - lipoprotein SACE_4420 12 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 134100445 Common - hypothetical protein SACE_3910 74 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 134098523 Common - probable exopolyphosphatase SACE_1948 155 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 134099060 Nonpathogen - hypothetical protein SACE_2503 1 COG4956 COG4956, Integral membrane protein (PIN domain superfamily) General function prediction only 134097974 Common - hypothetical protein SACE_1388 5 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 134097511 Common - hypothetical protein SACE_0913 3 None None None 134097838 Common - TetR-family transcriptional regulator SACE_1249 47 COG1309 AcrR, Transcriptional regulator Transcription 134099774 Common - acid phosphatase, class B SACE_3235 22 COG2503 COG2503, Predicted secreted acid phosphatase General function prediction only 134100932 Common - L-carnitine dehydratase/bile acid-inducible protein F SACE_4399 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 134101162 Nonpathogen - hypothetical protein SACE_4629 1 None None None 134098433 Common slpD proteinase (secreted protein) SACE_1857 28 None None None 134099369 Nonpathogen - hypothetical protein SACE_2826 1 None None None 134101728 Common - hypothetical protein SACE_5224 6 COG2246 COG2246, Predicted membrane protein Function unknown 134096628 Common - hypothetical protein SACE_0010 18 None None None 134103757 Common - AraC-family transcriptional regulator SACE_7337 130 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 134098171 Common - ROK-family transcriptional regulator SACE_1585 131 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 134102369 Common - hypothetical protein SACE_5922 11 COG5516 COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding General function prediction only 134098232 Common cobS putative cobalamin 5'-phosphate synthase SACE_1649 22 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 134099681 Common agaB2 putative alpha-galactosidase SACE_3139 18 COG3345 GalA, Alpha-galactosidase Carbohydrate transport and metabolism 134096645 Common - acetyl-CoA carboxylase, biotin carboxyl carrier protein SACE_0027 146 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 134097045 Common mutY A/G-specific adenine glycosylase SACE_0432 190 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 134100049 Common catD2 3-oxoadipate enol-lactone hydrolase SACE_3511 169 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134099577 Common - putative non-ribosomal peptide synthetase SACE_3035 218 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134101349 Common - peptidase S15 SACE_4820 70 COG2936 COG2936, Predicted acyl esterases General function prediction only 134099017 Common uspA3 universal stress protein family SACE_2455 12 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 134100530 Common - amidohydrolase SACE_3995 162 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 134097937 Nonpathogen - hypothetical protein SACE_1350 1 None None None 134098388 Common - nucleic acid binding, OB-fold,tRNA/helicase-type SACE_1809 13 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 134102874 Common - RNA methyltransferase TrmH, group 3 SACE_6440 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 134102385 Nonpathogen - hypothetical protein SACE_5938 1 None None None 134103575 Common purB,adsL adenylosuccinate lyase SACE_7153 197 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 134097802 Common rph ribonuclease PH SACE_1212 185 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 134096771 Common - protein of unknown function DUF1025 SACE_0154 45 COG3824 COG3824, Uncharacterized protein conserved in bacteria Function unknown 134102542 Common - guanine-specific ribonuclease N1 and T1 SACE_6105 25 COG4290 COG4290, Guanyl-specific ribonuclease Sa Nucleotide transport and metabolism 134101708 Common - secreted hydrolase SACE_5202 16 None None None 134097174 Common - malate dehydrogenase (oxaloacetate-decarboxylating) SACE_0563 199 COG0281 SfcA, Malic enzyme Energy production and conversion 134103363 Nonpathogen - hypothetical protein SACE_6936 1 None None None 134100779 Common - probable sugar efflux transporter, MFS superfamily SACE_4246 149 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134100405 Common glcD2 putative glycolate oxidase SACE_3870 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 134097354 Nonpathogen - hypothetical protein SACE_0748 1 None None None 134102836 Common sig49 RNA polymerase ECF-subfamily sigma factor SACE_6402 163 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 134097041 Common - antibiotic biosynthesis monooxygenase SACE_0428 19 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 134098577 Common - diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) SACE_2003 180 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 134096733 Common - sensor kinase, two-component system SACE_0115 104 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 134100476 Common - hypothetical protein SACE_3941 53 COG2388 COG2388, Predicted acetyltransferase General function prediction only 134099125 Nonpathogen - hypothetical protein SACE_2570 1 None None None 134103048 Common - IS1647-like transposase SACE_6618 42 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134098021 Common - competence protein ComEA helix-hairpin-helix region SACE_1435 85 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 134101756 Common - HAD-superfamily hydrolase, subfamily IIA SACE_5252 114 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 134097862 Common - putative Lsr2-like protein SACE_1273 16 None None None 134098053 Common draG1 ADP-ribosylglycohydrolase SACE_1467 25 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 134098033 Common - protein of unknown function DUF820 SACE_1447 36 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 134098801 Common chiB secreted chitinase SACE_2232 22 COG3469 COG3469, Chitinase Carbohydrate transport and metabolism 134101411 Common - putative ABC transport protein, ATP-binding component SACE_4881 247 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 134101285 Common - ATP-NAD/AcoX kinase SACE_4753 15 COG3199 COG3199, Uncharacterized conserved protein Function unknown 134101903 Common - secreted protein SACE_5402 24 None None None 134099700 Common - hypothetical protein SACE_3159 7 None None None 134102312 Common ftsI putative penicillin-binding (cell division related) protein SACE_5864 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 134096962 Common - probable transcriptional regulator, LysR family SACE_0348 189 COG0583 LysR, Transcriptional regulator Transcription 134102913 Common aveBII dTDP-glucose 4,6-dehydratase SACE_6480 231 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 134096762 Common cydCD putative ABC transporter ATP-binding protein SACE_0144 150 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 134099436 Common - putative methyltransferase SACE_2894 28 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134101385 Nonpathogen - hypothetical protein SACE_4855 1 None None None 134102650 Nonpathogen - hypothetical protein SACE_6213 1 None None None 134096863 Nonpathogen - hypothetical protein SACE_0247 1 None None None 134099803 Common - secreted protein SACE_3264 12 None None None 134099531 Common - putative secreted solute binding protein SACE_2989 100 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 134101614 Common - site-specific recombinase, phage integrase family SACE_5094 147 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 134097998 Common dmt dolichol-phosphate mannosyltransferase SACE_1412 149 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 134100805 Nonpathogen - hypothetical protein SACE_4272 1 None None None 134103079 Common - putative GntR-family transcriptional regulator SACE_6649 115 COG2188 PhnF, Transcriptional regulators Transcription 134101844 Common - acetyltransferase SACE_5342 96 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 134102224 Common plcN non-hemolytic phospholipase C precursor SACE_5775 35 COG3511 PlcC, Phospholipase C Cell envelope biogenesis, outer membrane 134099874 Common - monooxygenase, FAD-binding SACE_3335 28 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 134102799 Common - FAD linked oxidase-like SACE_6365 156 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 134102807 Common - probable metabolite transporter, MFS superfamily SACE_6373 128 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 134103565 Common purQ phosphoribosylformylglycinamidine synthase subunit I SACE_7143 232 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 134096666 Common - protein serine/threonine phosphatases SACE_0048 134 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 134103433 Nonpathogen - hypothetical protein SACE_7008 1 None None None 134098204 Common - acetyltransferase, GNAT family SACE_1620 12 COG3818 COG3818, Predicted acetyltransferase, GNAT superfamily General function prediction only 134098483 Common - transcriptional regulator, MarR family SACE_1908 50 COG1846 MarR, Transcriptional regulators Transcription 134100134 Common - hypothetical protein SACE_3596 121 COG1690 RtcB, Uncharacterized conserved protein Function unknown 134097239 Common - hypothetical protein SACE_0629 17 COG5373 COG5373, Predicted membrane protein Function unknown 134100556 Nonpathogen - hypothetical protein SACE_4021 1 None None None 134096780 Common - LGFP SACE_0163 17 COG5479 COG5479, Uncharacterized protein potentially involved in peptidoglycan biosynthesis Cell envelope biogenesis, outer membrane 134098609 Nonpathogen - hypothetical protein SACE_2035 1 None None None 134098540 Common - hypothetical protein SACE_1966 115 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 134098013 Nonpathogen - hypothetical protein SACE_1427 3 COG1141 Fer, Ferredoxin Energy production and conversion 134096904 Common - alpha/beta hydrolase fold-3 SACE_0290 125 COG0657 Aes, Esterase/lipase Lipid metabolism 134099859 Common pncA isochorismatase SACE_3320 36 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 134103259 Common rplV 50S ribosomal protein L22 SACE_6831 218 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 134099114 Common - TetR-family transcriptional regulator SACE_2559 90 COG1309 AcrR, Transcriptional regulator Transcription 134098223 Common - possible oxidoreductase SACE_1640 9 None None None 134099707 Nonpathogen - hypothetical protein SACE_3167 1 None None None 134101788 Common - lipoprotein, putative SACE_5285 11 None None None 134102692 Common - hypothetical protein SACE_6256 37 COG1637 COG1637, Predicted nuclease of the RecB family DNA replication, recombination, and repair 134101688 Nonpathogen - hypothetical protein SACE_5180 1 None None None 134097481 Common - hypothetical protein SACE_0883 12 None None None 134099010 Nonpathogen - hypothetical protein SACE_2448 3 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 134099604 Common - hydrogen:quinone oxidoreductase SACE_3062 89 COG0374 HyaB, Ni,Fe-hydrogenase I large subunit Energy production and conversion 134098396 Common - two-component system response regulator SACE_1817 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 134097020 Common panD aspartate 1-decarboxylase precursor SACE_0407 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 134102645 Common - ABC transporter, ATP-binding component SACE_6208 249 COG1119 ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA Inorganic ion transport and metabolism 134100531 Common - putative sporulation-control protein SACE_3996 20 COG4326 Spo0M, Sporulation control protein General function prediction only 134102698 Common - putative ABC transporter substrate-binding protein SACE_6262 86 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 134103526 Common - hypothetical protein SACE_7103 9 None None None 134099943 Common - serine/threonine dehydratase SACE_3404 207 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 134097593 Common - response regulator, two-component system SACE_0997 218 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 134101994 Common bkdC2 branched-chain alpha-keto acid dehydrogenase subunit E2 SACE_5544 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 134102378 Common - hypothetical protein SACE_5931 11 None None None 134102792 Common - cell wall surface anchor family protein SACE_6358 3 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 134099790 Common dapA1 putative dihydrodipicolinate synthase SACE_3251 227 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 134101109 Common - cupin 2, conserved barrel SACE_4576 16 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 134098667 Nonpathogen - PE-PGRS family protein SACE_2096 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 134102745 Common - hypothetical protein SACE_6310 14 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134103814 Common - putative inner membrane protein translocase component YidC SACE_7394 212 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 134097327 Common eryAI EryAI Erythromycin polyketide synthase modules 1 and 2 SACE_0721 213 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134096969 Common - hypothetical protein SACE_0355 2 COG2268 COG2268, Uncharacterized protein conserved in bacteria Function unknown 134099027 Common uspA3 universal stress protein family SACE_2465 39 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 134099876 Common - hypothetical protein SACE_3337 9 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 134103120 Common - putative serine/threonine protein kinase SACE_6690 140 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 134102605 Nonpathogen - hypothetical protein SACE_6168 1 COG1309 AcrR, Transcriptional regulator Transcription 134103704 Common - secreted hydrolase SACE_7282 15 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 134101811 Common chlB1 iterative type I polyketide synthase SACE_5308 209 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134103139 Common - hypothetical protein SACE_6709 7 None None None 134097755 Common - nitrate reductase (NADH) SACE_1163 107 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 134097358 Common rpsN 30S ribosomal protein S14 SACE_0752 202 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 134097968 Nonpathogen - hypothetical protein SACE_1382 4 COG4907 COG4907, Predicted membrane protein Function unknown 134098384 Common - hypothetical protein SACE_1805 19 None None None 134101796 Common - putative two-component system sensor kinase SACE_5293 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 134099071 Common - putative DNA-binding protein, HTH regulator SACE_2514 41 None None None 134100018 Common - transcriptional regulator, GntR-family SACE_3480 46 COG2186 FadR, Transcriptional regulators Transcription 134103750 Nonpathogen - hypothetical protein SACE_7330 2 None None None 134097106 Common - hypothetical protein SACE_0493 17 None None None 134101645 Common - hypothetical metabolite transport protein YhjE SACE_5135 155 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134102682 Nonpathogen - hypothetical protein SACE_6245 1 None None None 134097961 Common - glyoxalase/bleomycin resistance protein/dioxygenase superfamily SACE_1375 12 None None None 134103017 Nonpathogen - putative integral membrane protein (partial match) SACE_6586 4 None None None 134103731 Nonpathogen - hypothetical protein SACE_7309 1 None None None 134096752 Common - hypothetical protein SACE_0134 8 None None None 134100706 Common - hypothetical protein SACE_4173 5 COG3369 COG3369, Uncharacterized conserved protein Function unknown 134097242 Common citA4 citrate (Si) synthase SACE_0632 188 COG0372 GltA, Citrate synthase Energy production and conversion 134103407 Common - hypothetical protein SACE_6981 9 None None None 134103356 Common - hypothetical protein SACE_6929 21 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 134103031 Common - DNA polymerase, beta-like region SACE_6600 3 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 134103460 Common - heavy metal transport/detoxification protein SACE_7035 79 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 134097347 Nonpathogen - hypothetical protein SACE_0741 1 None None None 134102333 Nonpathogen - secreted protein SACE_5886 3 None None None 134103458 Common cprA transcriptional regulator SACE_7033 16 COG1309 AcrR, Transcriptional regulator Transcription 134097101 Common draG ADP-ribosylglycohydrolase SACE_0487 24 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 134101655 Common - Mn2+ and Fe2+ transporters of the NRAMP family-like protein SACE_5146 68 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 134102850 Common rmlC dTDP-4-dehydrorhamnose 3,5-epimerase SACE_6416 160 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 134099376 Common - two-component system response regulator SACE_2833 208 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 134097191 Common - putative ATPase involved in chromosome partitioning SACE_0581 16 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 134103294 Common - putative ABC transport system ATP-binding protein SACE_6866 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 134099551 Nonpathogen - hypothetical protein SACE_3009 1 None None None 134101670 Common - acetyltransferase SACE_5162 31 COG0456 RimI, Acetyltransferases General function prediction only 134103475 Common - ribosome-associated GTPase SACE_7050 163 COG1162 COG1162, Predicted GTPases General function prediction only 134099179 Common cypA cytochrome P450-like enzyme SACE_2631 75 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134099824 Common - lipolytic enzyme, G-D-S-L SACE_3285 14 None None None 134099403 Common - NADPH-dependent F420 reductase SACE_2861 47 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 134100723 Common - DNA polymerase bacteriophage-type SACE_4190 70 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 134100595 Common - acyl-CoA dehydrogenase, type 2-like SACE_4060 123 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134099148 Common - glycopeptide antibiotics resistance protein SACE_2593 7 COG4767 VanZ, Glycopeptide antibiotics resistance protein Defense mechanisms 134103318 Common nuoM NADH dehydrogenase I chain M SACE_6890 206 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 134102689 Common - sodium:solute symporter SACE_6252 157 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 134098606 Common hisS histidyl-tRNA synthetase SACE_2032 249 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 134097735 Nonpathogen - hypothetical protein SACE_1140 1 None None None 134096967 Common - RpiR-family transcriptional regulator SACE_0353 120 COG1737 RpiR, Transcriptional regulators Transcription 134101352 Common ophB ABC transporter, permease protein SACE_4823 218 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 134098049 Common - hypothetical protein SACE_1463 31 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 134101804 Common - probable N-acyl-D-amino-acid deacylase SACE_5301 54 COG3653 COG3653, N-acyl-D-aspartate/D-glutamate deacylase Secondary metabolites biosynthesis, transport, and catabolism 134103582 Nonpathogen - hypothetical protein SACE_7160 1 None None None 134103636 Common - small multidrug resistance protein, SMR family SACE_7214 77 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 134096784 Common - membrane-associated phospholipid phosphatase SACE_0167 7 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 134100846 Common - nucleoside diphosphate kinase regulator SACE_4313 2 COG0782 GreA, Transcription elongation factor Transcription 134098307 Common - putative transporter SACE_1725 41 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 134103180 Common - hypothetical protein SACE_6750 6 COG2267 PldB, Lysophospholipase Lipid metabolism 134098759 Common echA14 enoyl-CoA hydratase/isomerase SACE_2189 182 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 134101701 Common - TrkA-C SACE_5194 49 COG0490 COG0490, Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels Inorganic ion transport and metabolism 134103384 Common - excisionase/Xis, DNA-binding SACE_6958 24 COG3311 AlpA, Predicted transcriptional regulator Transcription 134100362 Common - transcriptional regulator, TetR family SACE_3827 84 COG1309 AcrR, Transcriptional regulator Transcription 134097075 Common otsA trehalose-6-phosphate synthase SACE_0462 96 COG0380 OtsA, Trehalose-6-phosphate synthase Carbohydrate transport and metabolism 134099799 Common - hypothetical protein SACE_3260 50 COG3542 COG3542, Uncharacterized conserved protein Function unknown 134101850 Common - putative carboxymethylenebutenolidase precursor (dienelactone hydrolase) (DLH) SACE_5348 99 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 134098765 Common - putative peptide transport permease SACE_2195 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 134099251 Common - cyclase/dehydrase SACE_2705 29 COG5637 COG5637, Predicted integral membrane protein Function unknown 134101791 Common - transcriptional regulator, IclR family SACE_5288 102 COG1414 IclR, Transcriptional regulator Transcription 134102161 Common - retron-type reverse transcriptase SACE_5712 39 None None None 134099623 Common - LysR-family transcriptional regulator SACE_3081 166 COG0583 LysR, Transcriptional regulator Transcription 134101428 Common - hypothetical protein SACE_4898 6 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 134100394 Common - GntR-family transcriptional regulator SACE_3859 131 COG2186 FadR, Transcriptional regulators Transcription 134099905 Common - feruloyl esterase SACE_3366 51 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 134100429 Nonpathogen - integral membrane protein SACE_3894 2 None None None 134101483 Common - IS3 family transposase SACE_4953 122 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 134103261 Common rplB 50S ribosomal protein L2 SACE_6833 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 134098726 Common opcA oxppcycle protein SACE_2156 23 COG3429 COG3429, Glucose-6-P dehydrogenase subunit Carbohydrate transport and metabolism 134099104 Common - transcriptional regulator, LacI family SACE_2549 126 COG1609 PurR, Transcriptional regulators Transcription 134098836 Common - hypothetical protein SACE_2267 27 COG4552 Eis, Predicted acetyltransferase involved in intracellular survival and related acetyltransferases General function prediction only 134099957 Common - aminotransferase class III SACE_3418 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 134100418 Common - LysR-family transcriptional regulator SACE_3883 165 COG0583 LysR, Transcriptional regulator Transcription 134102979 Common deoD,punA purine nucleoside phosphorylase SACE_6547 106 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 134103626 Common - MarR-family transcriptional regulator SACE_7204 44 COG1846 MarR, Transcriptional regulators Transcription 134098012 Common cypA cytochrome P450-like enzyme SACE_1426 89 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134098237 Common - HesB/YadR/YfhF SACE_1654 165 COG0316 IscA, Uncharacterized conserved protein Function unknown 134097545 Common rbsR putative LacI-family transcriptional regulator SACE_0947 128 COG1609 PurR, Transcriptional regulators Transcription 134099130 Common - transposase SACE_2575 21 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134103251 Common rpsN 30S ribosomal protein S14 SACE_6823 200 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 134099197 Common - integral membrane protein SACE_2650 40 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 134103136 Common - metal dependent phosphohydrolase SACE_6706 34 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 134099086 Common - IS1647-like transposase SACE_2530 34 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134097553 Common - two-component system response regulator SACE_0956 210 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134099007 Common - beta-phosphoglucomutase hydrolase SACE_2445 50 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 134103051 Common - probable copper resistance transporter SACE_6621 21 COG3336 COG3336, Predicted membrane protein Function unknown 134100183 Common - putative TetR-family transcriptional regulator SACE_3645 48 COG1309 AcrR, Transcriptional regulator Transcription 134101771 Nonpathogen - hypothetical protein SACE_5267 1 None None None 134100509 Common - hypothetical protein SACE_3974 10 None None None 134101594 Common aspA aspartate ammonia-lyase SACE_5071 230 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 134097643 Common - ABC sugar transporter, permease component SACE_1047 177 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 134102184 Nonpathogen - hypothetical protein SACE_5735 1 None None None 134099221 Common - tetratricopeptide TPR_2 SACE_2675 97 COG0457 NrfG, FOG: TPR repeat General function prediction only 134100514 Common - dimethylallyltranstransferase / geranyltranstransferase / geranylgeranyl pyrophosphate synthetase SACE_3979 241 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 134101923 Common - hypothetical protein SACE_5424 5 COG2306 COG2306, Uncharacterized conserved protein Function unknown 134099852 Common - two-component system sensor kinase SACE_3313 8 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 134102762 Common - mandelate racemase/muconate lactonizing enzyme SACE_6327 112 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 134103668 Common - short chain dehydrogenase SACE_7246 232 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 134102309 Common aarC acetyl-CoA hydrolase/transferase SACE_5861 97 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 134097601 Common typA GTP-binding elongation factor family protein SACE_1005 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 134100710 Common - hypothetical protein SACE_4177 38 None None None 134098134 Common - GntR-family transcriptional regulator SACE_1548 118 COG1802 GntR, Transcriptional regulators Transcription 134097380 Common galU UTP--glucose-1-phosphate uridylyltransferase SACE_0774 217 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 134101004 Common - hypothetical protein SACE_4471 10 None None None 134100381 Common gcvH glycine cleavage system H protein SACE_3846 187 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 134102132 Common - DNA ligase, ATP-dependent SACE_5682 100 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 134098789 Common - transcriptional regulator, XRE family SACE_2220 6 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 134099572 Common - hypothetical protein SACE_3030 25 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 134100150 Common add adenosine deaminase SACE_3612 107 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 134098624 Common - secreted solute-binding protein,aminodeoxychorismate lyase-like SACE_2054 169 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 134098808 Common - antibiotic biosynthesis monooxygenase domain protein SACE_2239 29 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 134100837 Common - Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II SACE_4304 199 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134096881 Common - two-component system response regulator SACE_0266 210 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 134101516 Common ctaE cytochrome c oxidase subunit III SACE_4988 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 134101363 Nonpathogen - hypothetical protein SACE_4834 1 None None None 134102071 Common - transcriptional regulatory protein (probably ArsR-family) SACE_5621 140 COG0640 ArsR, Predicted transcriptional regulators Transcription 134099332 Common - putative glycine betaine transport ATP-binding protein SACE_2787 245 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 134103280 Common - hypothetical protein SACE_6852 3 None None None 134100379 Common - protein of unknown function DUF151 SACE_3844 78 COG1259 COG1259, Uncharacterized conserved protein Function unknown 134102562 Common ung uracil-DNA glycosylase SACE_6125 129 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 134097471 Common - putative restriction modification system DNA specificity domain SACE_0869 77 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 134101321 Common - two-component system response regulator SACE_4789 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 134100625 Common - alpha-ketoglutarate transporter, MFS superfamily SACE_4090 135 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134098476 Nonpathogen - hypothetical protein SACE_1901 1 None None None 134099019 Common uspA3 universal stress protein family SACE_2457 48 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 134099297 Common - ISHa1942 transposase A homolog SACE_2752 68 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 134103639 Common - alkanal monooxygenase (luciferase) SACE_7217 112 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 134098147 Common - hypothetical protein SACE_1561 4 COG1396 HipB, Predicted transcriptional regulators Transcription 134099670 Common - hypothetical protein SACE_3128 7 None None None 134102205 Common hisF imidazoleglycerol-phosphate synthase cyclase SACE_5756 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 134099910 Common fabG 3-oxoacyl-[acyl-carrier-protein] reductase SACE_3371 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134102831 Common - DGPF domain protein SACE_6397 43 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 134098324 Common - protein of unknown function Mtu_121 SACE_1742 29 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 134096808 Nonpathogen - hypothetical protein SACE_0191 1 None None None 134097950 Common - putative esterase SACE_1364 8 COG0627 COG0627, Predicted esterase General function prediction only 134098656 Common - transcriptional regulator (MarR-family) SACE_2085 10 COG1846 MarR, Transcriptional regulators Transcription 134100996 Common - hypothetical protein SACE_4463 13 None None None 134099786 Common - transcriptional regulator, XRE family SACE_3247 73 COG1396 HipB, Predicted transcriptional regulators Transcription 134098936 Common - IS1647-like transposase SACE_2372 39 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134097897 Common amo luciferase-like monooxygenase SACE_1310 106 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 134102969 Common hur hydroxyurea phosphotransferase SACE_6537 25 COG3570 StrB, Streptomycin 6-kinase Defense mechanisms 134098870 Common - hypothetical protein SACE_2305 5 COG2040 MHT1, Homocysteine/selenocysteine methylase (S-methylmethionine-dependent) Amino acid transport and metabolism 134103107 Nonpathogen - hypothetical protein SACE_6677 2 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 134098918 Common - triacylglycerol lipase SACE_2354 19 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 134100661 Common - probable unsaturated glucuronyl hydrolase SACE_4128 14 None None None 134098530 Common - hypothetical protein SACE_1955 9 COG0073 ARC1, EMAP domain General function prediction only 134102175 Common - ErfK/YbiS/YcfS/YnhG SACE_5726 20 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 134099078 Common - transposase SACE_2522 21 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134097747 Nonpathogen - hypothetical protein SACE_1155 1 None None None 134100785 Common - amino acid permease-associated region SACE_4252 158 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 134097740 Common - hypothetical protein SACE_1148 8 None None None 134099463 Common - iron ABC transporter substrate-binding protein SACE_2921 72 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 134101518 Common - transposase, ISlxx1 SACE_4990 90 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 134096644 Common accA acetyl carboxylase SACE_0026 192 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 134102414 Common - lysine exporter protein (LysE/YggA) SACE_5968 116 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 134102458 Common - regulatory protein SACE_6020 28 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 134097450 Common - putative peptide ABC transporter, permease component SACE_0845 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 134103567 Nonpathogen - hypothetical protein SACE_7145 1 None None None 134098723 Common - secreted protein SACE_2153 39 COG1649 COG1649, Uncharacterized protein conserved in bacteria Function unknown 134100529 Common fadA 3-ketoacyl-CoA thiolase SACE_3994 173 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 134100058 Nonpathogen - hypothetical protein SACE_3520 1 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 134098946 Common - hypothetical protein SACE_2382 5 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134098712 Common lamA1 endo-1,3-beta-glucanase SACE_2142 39 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 134103119 Nonpathogen - hypothetical protein SACE_6689 1 None None None 134099281 Common fadA6 acetyl-CoA acetyltransferase SACE_2736 186 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 134103643 Nonpathogen - hypothetical protein SACE_7221 1 None None None 134097665 Common - hypothetical protein SACE_1069 9 None None None 134100791 Common - sugar ABC transporter, ATP-binding protein SACE_4258 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 134101506 Common - hypothetical protein SACE_4978 15 COG4644 COG4644, Transposase and inactivated derivatives, TnpA family DNA replication, recombination, and repair 134098257 Common - ABC transporter, ATP-binding protein SACE_1674 246 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 134099736 Common proY aromatic amino acid permease SACE_3197 153 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 134099687 Common fprC ferredoxin reductase SACE_3145 218 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 134103524 Common glnR transcriptional regulator SACE_7101 198 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 134101244 Common - AsnC-family transcriptional regulator SACE_4712 40 COG1522 Lrp, Transcriptional regulators Transcription 134097223 Common - acetyltransferase, GNAT family SACE_0613 19 COG0456 RimI, Acetyltransferases General function prediction only 134101607 Nonpathogen - hypothetical protein SACE_5086 1 None None None 134097461 Nonpathogen - hypothetical protein SACE_0857 3 None None None 134098795 Common cysS2 cysteinyl-tRNA synthetase SACE_2226 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 134098331 Common - hypothetical protein SACE_1749 4 None None None 134100143 Common - oxidase SACE_3605 34 COG1791 COG1791, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 134103695 Common - hypothetical protein SACE_7273 4 None None None 134098342 Common - SOS-response transcriptional repressor, LexA SACE_1760 173 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 134097395 Common - ABC-type transporter, ATPase component SACE_0789 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 134101220 Nonpathogen - conserved hypothetical protein, glycine-rich repeat SACE_4688 1 None None None 134096699 Nonpathogen - hypothetical protein SACE_0081 1 None None None 134103604 Common - RNA polymerase, sigma-24 subunit, ECF subfamily SACE_7182 129 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 134096692 Common - hypothetical protein SACE_0074 27 COG4549 COG4549, Uncharacterized protein conserved in bacteria Function unknown 134102215 Common - putative two-component system response regulator SACE_5766 44 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 134102951 Common glpK glycerol kinase SACE_6518 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 134099898 Common - lipolytic enzyme, G-D-S-L SACE_3359 15 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 134102222 Nonpathogen - hypothetical protein SACE_5773 1 None None None 134102453 Common - agmatinase, putative SACE_6015 138 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 134098298 Common - hypothetical protein SACE_1716 5 None None None 134098118 Common aceE pyruvate dehydrogenase subunit E1 SACE_1532 135 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 134098619 Common serA glycerate dehydrogenase SACE_2049 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 134100650 Common aofH putative flavin-containing monoamine oxidase SACE_4116 25 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 134101366 Common - IS1647-like transposase SACE_4837 27 None None None 134102865 Common - transcriptional regulatory protein SACE_6431 101 COG2606 EbsC, Uncharacterized conserved protein Function unknown 134098560 Common coaA,panK,rts pantothenate kinase SACE_1986 78 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 134103061 Nonpathogen - hypothetical protein SACE_6631 2 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 134102754 Common sugI probable sugar-transport integral membrane protein SugI SACE_6319 126 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134103685 Common - two-component system sensor kinase SACE_7263 138 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 134098754 Common - lycopene cyclase, beta and epsilon SACE_2184 9 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 134098747 Common csdB cysteine desulfurase / selenocysteine lyase SACE_2177 237 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 134097409 Common - putative ABC transporter ATP-binding protein SACE_0804 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 134098645 Common pepQ Xaa-Pro dipeptidase SACE_2074 245 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 134102926 Nonpathogen - hypothetical protein SACE_6493 1 None None None 134096940 Common - hypothetical protein SACE_0326 54 COG3217 COG3217, Uncharacterized Fe-S protein General function prediction only 134099781 Common - putative acetyl/propionyl-CoA carboxylase alpha subunit SACE_3242 232 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 134096823 Nonpathogen - ABC-2 type transporter SACE_0206 12 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 134096811 Common - FAD linked oxidase-like protein SACE_0194 130 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 134100971 Common ybjJ putative DeoR-type transcriptional regulator SACE_4438 60 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134098414 Common - chlorite dismutase SACE_1838 40 COG3253 COG3253, Uncharacterized conserved protein Function unknown 134097809 Common - transcriptional regulator, XRE family SACE_1219 6 None None None 134097126 Common - hypothetical protein SACE_0515 17 None None None 134100686 Nonpathogen - integral membrane protein SACE_4153 3 None None None 134102451 Nonpathogen - hypothetical protein SACE_6007 1 None None None 134098960 Common - hypothetical protein SACE_2397 3 None None None 134099306 Common - hypothetical protein SACE_2761 137 COG0583 LysR, Transcriptional regulator Transcription 134097526 Common - DeoR family transcriptional regulator of sugar metabolism SACE_0928 113 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 134100490 Common - beta-lactamase-like SACE_3955 103 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 134102465 Common sitA iron transport protein-binding protein SACE_6027 157 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 134098216 Common - probable alkanesulfonate monooxygenase SACE_1633 89 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 134101145 Nonpathogen - hypothetical protein SACE_4612 10 COG4274 COG4274, Uncharacterized conserved protein Function unknown 134098861 Common - hypothetical protein SACE_2293 5 None None None 134100699 Common - putative transcriptional regulator SACE_4166 39 COG1695 COG1695, Predicted transcriptional regulators Transcription 134098913 Nonpathogen - hypothetical protein SACE_2349 3 None None None 134099547 Common - hypothetical protein SACE_3005 19 None None None 134101731 Common - peptidase SACE_5227 106 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 134099589 Nonpathogen - hypothetical protein SACE_3047 1 None None None 134101526 Common - protein of unknown function DUF574 SACE_4998 12 None None None 134100566 Common phzM probable phenazine-specific methyltransferase SACE_4031 48 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 134100301 Common gabT2 4-aminobutyrate transaminase SACE_3766 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 134100065 Common - sulfate adenylyltranferase, adenylylsulfate kinase SACE_3527 143 COG0529 CysC, Adenylylsulfate kinase and related kinases Inorganic ion transport and metabolism 134096887 Common - integral membrane protein SACE_0273 162 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 134097672 Common chiA2 chitinase A SACE_1076 19 COG3469 COG3469, Chitinase Carbohydrate transport and metabolism 134102053 Common - hypothetical protein SACE_5603 49 COG3558 COG3558, Uncharacterized protein conserved in bacteria Function unknown 134097003 Common - multidrug transporter, MFS superfamily SACE_0390 179 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134098968 Common phdB probable pyruvate dehydrogenase E1 component,beta subunit SACE_2406 215 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 134099937 Common pccB propionyl-CoA carboxylase beta SACE_3398 208 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 134103783 Common - hypothetical protein SACE_7363 10 None None None 134103000 Common - transcriptional regulator, PadR-like family SACE_6568 54 COG1695 COG1695, Predicted transcriptional regulators Transcription 134097877 Common - alcohol dehydrogenase, zinc-binding domain protein SACE_1290 50 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 134099429 Common ribD riboflavin-specific deaminase SACE_2887 226 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 134102549 Common - cytochrome P450 monooxygenase SACE_6112 64 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134100116 Nonpathogen - putative integral membrane protein SACE_3578 2 COG2259 COG2259, Predicted membrane protein Function unknown 134099979 Common - epoxide hydrolase SACE_3441 35 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134100272 Common ama2 putative alpha-mannosidase SACE_3737 50 COG0383 AMS1, Alpha-mannosidase Carbohydrate transport and metabolism 134098780 Nonpathogen - hypothetical protein SACE_2210 1 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 134101312 Nonpathogen - hypothetical protein SACE_4780 1 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 134102443 Common repSA replication initiator protein SACE_5999 5 None None None 134100416 Common - sarcosine oxidase subunit beta SACE_3881 166 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 134101033 Common - transcriptional regulator, GntR family SACE_4500 123 COG1802 GntR, Transcriptional regulators Transcription 134103080 Nonpathogen - hypothetical protein SACE_6650 1 None None None 134099420 Common tcmO putative 8-O-methyltransferase SACE_2878 52 COG2345 COG2345, Predicted transcriptional regulator Transcription 134100864 Common hopE squalene/phytoene synthase SACE_4331 92 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 134097178 Common moaD2 MoaD2 SACE_0568 3 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 134098113 Common - regulator of polyketide synthase expression-like SACE_1527 25 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 134098858 Common - hypothetical protein SACE_2290 18 None None None 134099483 Common - helix-turn-helix, fis-type SACE_2941 3 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 134100683 Common lao2 L-amino-acid oxidase SACE_4150 63 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 134102482 Common - endonuclease SACE_6045 145 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 134102165 Common - lysine exporter protein (LysE/YggA) SACE_5716 115 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 134096638 Common - hypothetical protein SACE_0020 4 COG3319 COG3319, Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases Secondary metabolites biosynthesis, transport, and catabolism 134099041 Nonpathogen - hypothetical protein SACE_2481 1 None None None 134102260 Common - TetR-family transcriptional regulator SACE_5812 36 COG1309 AcrR, Transcriptional regulator Transcription 134099719 Nonpathogen - hypothetical protein SACE_3179 1 None None None 134100814 Common arcB4 putative ornithine cyclodeaminase SACE_4281 31 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 134103376 Common - putative fatty-acid--CoA ligase SACE_6950 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134100894 Common - hypothetical protein SACE_4361 15 None None None 134099651 Nonpathogen - hypothetical protein SACE_3109 5 None None None 134100510 Common - hypothetical protein SACE_3975 4 COG3655 COG3655, Predicted transcriptional regulator Transcription 134103218 Nonpathogen - hypothetical protein SACE_6790 1 None None None 134099953 Common gudP MFS transporter, phthalate permease family SACE_3414 202 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 134101524 Common - hypothetical protein SACE_4996 5 COG3871 COG3871, Uncharacterized stress protein (general stress protein 26) General function prediction only 134102756 Common - probable ATP-binding component of ABC transporter SACE_6321 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 134101647 Common - hypothetical protein SACE_5138 17 COG5516 COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding General function prediction only 134097422 Common glmU putative UDP-N-acetylglucosamine pyrophosphorylase SACE_0817 236 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 134098340 Common - transposase for IS3508i SACE_1758 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 134099382 Common fprC ferredoxin reductase SACE_2839 94 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 134102729 Common rpmE 50S ribosomal protein L31 SACE_6293 195 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 134102121 Nonpathogen - hypothetical protein SACE_5671 1 None None None 134098732 Common - putative multidrug resistance protein SACE_2162 192 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134097576 Common - pterin-4-alpha-carbinolamine dehydratase SACE_0980 108 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 134102520 Nonpathogen - hypothetical protein SACE_6083 1 None None None 134099613 Common gmhA phosphoheptose isomerase SACE_3071 122 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 134097335 Common - thioesterase, erythromycin biosynthesis SACE_0729 50 COG3208 GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 134100085 Common paaD probable phenylacetic acid degradation protein SACE_3547 43 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 134103794 Common - phytase SACE_7374 27 COG4222 COG4222, Uncharacterized protein conserved in bacteria Function unknown 134103151 Common - integral membrane protein SACE_6721 75 COG2949 SanA, Uncharacterized membrane protein Function unknown 134101571 Common pcaR transcriptional regulator, IclR family SACE_5047 114 COG1414 IclR, Transcriptional regulator Transcription 134097499 Common tnp transposase, ISlxx5 SACE_0901 63 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 134100031 Common - putative ABC transport system permease protein SACE_3493 37 COG0390 COG0390, ABC-type uncharacterized transport system, permease component General function prediction only 134097438 Nonpathogen - hypothetical protein SACE_0833 2 None None None 134102534 Common - putative glycosyl transferase SACE_6097 136 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 134102824 Common kbl 2-amino-3-ketobutyrate coenzyme A ligase SACE_6390 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 134098676 Common - tRNA/rRNA methyltransferase (SpoU) SACE_2106 161 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 134099154 Common csbX alpha-ketoglutarate permease SACE_2599 12 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 134099839 Common - hypothetical protein SACE_3300 6 None None None 134101588 Nonpathogen - hypothetical protein SACE_5064 1 None None None 134102529 Common - FAD linked oxidase-like SACE_6092 38 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 134102888 Common - amino acid permease-associated region SACE_6455 151 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 134100310 Common - LysR-family transcriptional regulator SACE_3775 182 COG0583 LysR, Transcriptional regulator Transcription 134099203 Common - putative transposase SACE_2656 67 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134098854 Common - amidohydrolase 3 SACE_2286 95 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 134101021 Common - hypothetical protein SACE_4488 4 None None None 134103201 Nonpathogen - hypothetical protein SACE_6772 1 COG5373 COG5373, Predicted membrane protein Function unknown 134100067 Common cysQ inositol monophosphatase family protein SACE_3529 134 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 134103109 Common - putative surface layer protein SACE_6679 8 COG3391 COG3391, Uncharacterized conserved protein Function unknown 134097113 Nonpathogen - hypothetical protein SACE_0501 1 None None None 134101195 Common - oxidoreductase, aldo/keto reductase family SACE_4662 181 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 134097540 Common rbsC ribose ABC transporter, permease protein SACE_0942 110 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 134103325 Common nuoF NADH dehydrogenase I chain F SACE_6897 162 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 134100424 Common - FAD-binding oxidoreductase SACE_3889 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 134100734 Common - amino acid permease-associated region SACE_4201 187 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 134099881 Common - integral membrane protein SACE_3342 5 None None None 134102906 Common - glycosyl transferase, group 1 SACE_6473 160 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 134101553 Common - transcriptional regulator, BadM/Rrf2 family SACE_5029 5 COG1959 COG1959, Predicted transcriptional regulator Transcription 134100717 Common - acetyltransferase (GNAT) family protein SACE_4184 15 COG0456 RimI, Acetyltransferases General function prediction only 134102038 Common - integral membrane protein SACE_5588 40 COG0628 PerM, Predicted permease General function prediction only 134101954 Common - hypothetical cytosolic protein SACE_5456 4 None None None 134096891 Nonpathogen - hypothetical protein SACE_0277 1 None None None 162316926 Common cysS cysteinyl-tRNA synthetase SACE_0443 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 134102784 Common - hypothetical protein SACE_6350 19 COG4449 COG4449, Predicted protease of the Abi (CAAX) family General function prediction only 134098647 Common - NusB antitermination factor SACE_2076 181 COG0781 NusB, Transcription termination factor Transcription 134100773 Common - hypothetical protein SACE_4240 12 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 134101252 Common - 5'-nucleotidase-like protein SACE_4720 126 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 134103231 Common - DNA-directed RNA polymerase subunit alpha SACE_6803 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 134096945 Common nth putative endonuclease III SACE_0331 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 134101509 Common - possible flavin binding monooxygenase SACE_4981 18 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 134100835 Common - hypothetical protein SACE_4302 14 None None None 134103346 Nonpathogen - hypothetical protein SACE_6919 1 None None None 134100265 Common galE1 UDP-glucose 4-epimerase SACE_3730 51 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 134101181 Common - prenyltransferase/squalene oxidase SACE_4648 31 COG1657 SqhC, Squalene cyclase Lipid metabolism 134099520 Common - putative dehydrogenase, oxidoreductase FAD flavoprotein SACE_2978 105 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 134100548 Common - short-chain dehydrogenase/reductase SDR SACE_4013 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134100822 Nonpathogen - hypothetical protein SACE_4289 1 None None None 134101190 Common iolG myo-inositol 2-dehydrogenase SACE_4657 156 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 134097009 Common ftsH putative cell division protein SACE_0396 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 134098546 Common - hypothetical protein SACE_1972 9 None None None 134100617 Common - pentachlorophenol monooxygenase SACE_4082 92 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 134101463 Common - NmrA-like SACE_4933 63 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 134101186 Common - protein kinase/transcriptional regulator, LuxR family SACE_4653 102 COG3903 COG3903, Predicted ATPase General function prediction only 134103767 Common dnaB replicative DNA helicase SACE_7347 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 134099219 Common - oligopeptide ABC transporter ATP-binding protein SACE_2672 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 134098958 Common - hypothetical protein SACE_2394 10 None None None 134102575 Common plsC 1-acylglycerol-3-phosphate O-acyltransferase SACE_6138 116 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 134103007 Common deoA thymidine phosphorylase SACE_6575 119 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 134097904 Common - alpha-L-fucosidase SACE_1317 28 COG3669 COG3669, Alpha-L-fucosidase Carbohydrate transport and metabolism 134097824 Nonpathogen - hypothetical protein SACE_1235 1 None None None 134097946 Common - ATP-dependent Clp protease proteolytic subunit 1 SACE_1360 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 134101207 Common - putative transposase SACE_4675 51 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 134103082 Common - protein of unknown function DUF606 SACE_6652 17 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 134096910 Common - isoniazid inductible gene protein IniC SACE_0296 29 COG1160 COG1160, Predicted GTPases General function prediction only 134100079 Common - possible transcriptional regulator, TetR family SACE_3541 109 COG1309 AcrR, Transcriptional regulator Transcription 134100786 Common xylR xylose operon repressor SACE_4253 135 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 134103320 Common nuoK NADH dehydrogenase subunit K SACE_6892 158 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 134097483 Common - hypothetical protein SACE_0885 15 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 134100191 Common - integral membrane protein TerC SACE_3653 94 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 134099228 Common - protein of unknown function DUF6, transmembrane SACE_2682 5 None None None 134097690 Nonpathogen - hypothetical protein SACE_1094 1 None None None 134102624 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase SACE_6187 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 134096931 Common - probable anion transporter ATPase SACE_0317 11 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 134103544 Nonpathogen - hypothetical protein SACE_7122 1 None None None 134099587 Nonpathogen - hypothetical protein SACE_3045 3 None None None 134100506 Common - putative fosmidmycin resistance protein SACE_3971 70 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 134098971 Common uspA3 universal stress protein family SACE_2409 61 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 134102805 Common - MerR-family transcriptional regulator SACE_6371 9 COG0789 SoxR, Predicted transcriptional regulators Transcription 134097683 Nonpathogen - PE-PGRS family protein SACE_1087 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 134098739 Common - hypothetical protein SACE_2169 8 None None None 134103412 Common - YbaK/prolyl-tRNA synthetase associated region SACE_6986 13 COG2606 EbsC, Uncharacterized conserved protein Function unknown 134096928 Common pon1 penicillin binding protein (class A) SACE_0314 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 134099389 Common - two-component response regulator SACE_2846 186 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 134101210 Nonpathogen - probable multidrug resistance transporter, MFS superfamily SACE_4678 1 None None None 134100127 Common - oxidoreductase SACE_3589 185 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 134099660 Common - binding protein/LacI transcriptional regulator SACE_3118 128 COG1609 PurR, Transcriptional regulators Transcription 134101292 Common rocF arginase SACE_4760 11 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 134103208 Common glmM putative phosphoglucomutase/phosphomannomutase SACE_6779 240 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 134099932 Common - AP endonuclease, family 1:exodeoxyribonuclease III xth SACE_3393 187 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 134098405 Common - IS1533 transposase SACE_1827 5 None None None 134100269 Common - hypothetical protein SACE_3734 5 None None None 134102290 Common - ABC transporter, nucleotide binding/ATPase protein SACE_5842 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 134102445 Nonpathogen - hypothetical protein SACE_6001 1 None None None 134098281 Common - hypothetical protein SACE_1699 3 None None None 134103533 Common - hypothetical protein SACE_7110 16 None None None 134102299 Common murG undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase SACE_5851 206 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 134098263 Common - transcriptional regulator, AsnC family SACE_1680 27 COG1522 Lrp, Transcriptional regulators Transcription 134102150 Common gcvT glycine cleavage system aminomethyltransferase T SACE_5701 179 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 134103165 Common - transthyretin SACE_6735 63 COG2351 COG2351, Transthyretin-like protein General function prediction only 134100287 Common - endoglycoceramidase SACE_3752 16 COG2730 BglC, Endoglucanase Carbohydrate transport and metabolism 134097379 Common - 5-formyltetrahydrofolate cyclo-ligase SACE_0773 23 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 134102171 Common - transcriptional regulator, TetR family SACE_5722 30 COG1309 AcrR, Transcriptional regulator Transcription 134099139 Common - general substrate transporter SACE_2584 124 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134102651 Common pksA,pks transcriptional regulator SACE_6214 42 COG1309 AcrR, Transcriptional regulator Transcription 134097000 Nonpathogen - hypothetical protein SACE_0387 1 None None None 134099354 Common - hypothetical protein SACE_2811 4 None None None 134101881 Common - putative phosphotransferase SACE_5379 60 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 134101154 Common - TetR-family transcriptional regulator SACE_4621 40 COG1309 AcrR, Transcriptional regulator Transcription 134099359 Common map methionine aminopeptidase SACE_2816 248 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 134100544 Common - transcriptional regulator, LysR family SACE_4009 190 COG0583 LysR, Transcriptional regulator Transcription 134100857 Nonpathogen - hypothetical membrane protein SACE_4324 3 None None None 134099153 Common - transcriptional regulator, LuxR family SACE_2598 87 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134101945 Common - two component transcriptional regulator, LuxR family SACE_5447 92 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134098157 Common - hypothetical protein SACE_1571 16 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 134098099 Common add adenosine deaminase SACE_1513 102 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 134098444 Common - stress-like protein SACE_1868 38 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 134097589 Common - probable peptide ABC transporter,substrate-binding protein SACE_0993 200 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 134097986 Common - phosphodiesterase/alkaline phosphatase D SACE_1400 59 COG3540 PhoD, Phosphodiesterase/alkaline phosphatase D Inorganic ion transport and metabolism 134101137 Common dapA dihydrodipicolinate synthase SACE_4604 231 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 134101712 Common nupX putative Na+ dependent nucleoside transporter SACE_5206 68 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 134096975 Common blaA1 beta-lactamase SACE_0361 162 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 134099633 Common - oxidoreductase, iron-sulphur binding subunit SACE_3091 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 134100247 Common tnp transposase, ISlxx5 SACE_3711 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 134101545 Nonpathogen - hypothetical protein SACE_5021 1 None None None 134102160 Common - DedA-like protein SACE_5711 131 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 134099860 Common - secreted protein SACE_3321 7 None None None 134102658 Common - MarR-transcriptional regulator SACE_6221 90 COG1846 MarR, Transcriptional regulators Transcription 134100284 Common - oxidoreductase, short chain dehydrogenase/reductase family SACE_3749 161 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134099841 Common - TetR-family transcriptional regulator SACE_3302 43 COG1309 AcrR, Transcriptional regulator Transcription 134097547 Common - carbohydrate kinase, FGGY SACE_0949 185 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 134096738 Common clfB clumping factor B SACE_0120 13 COG3162 COG3162, Predicted membrane protein Function unknown 134097638 Common - citrate (pro-3S)-lyase beta subunit SACE_1042 117 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 134096990 Common topA DNA topoisomerase I SACE_0377 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 134096718 Common - permease of the drug/metabolite transporter (DMT) superfamily SACE_0100 18 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 134099561 Nonpathogen - PE-PGRS family protein SACE_3019 1 None None None 134099088 Common - transposase, mutator type SACE_2532 51 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 134101002 Common - TetR family transcriptional regulatory protein SACE_4469 19 COG1309 AcrR, Transcriptional regulator Transcription 134099111 Common tnp11a(ISCg11a) transposase-fragment SACE_2556 27 None None None 134101913 Common - phosphoglycerate mutase SACE_5412 19 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 134099867 Nonpathogen - hypothetical protein SACE_3328 1 None None None 134099081 Common ureF urease accessroy protein SACE_2525 6 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 134100358 Common - hypothetical protein SACE_3823 65 COG4301 COG4301, Uncharacterized conserved protein Function unknown 134101766 Common - hypothetical protein SACE_5262 11 COG3603 COG3603, Uncharacterized conserved protein Function unknown 134102188 Common - transcriptional regulator, XRE family SACE_5739 6 None None None 134100123 Common - N-acyl-D-amino-acid deacylase SACE_3585 52 COG3653 COG3653, N-acyl-D-aspartate/D-glutamate deacylase Secondary metabolites biosynthesis, transport, and catabolism 134102439 Common - transglycosylase-associated protein SACE_5995 4 COG2261 COG2261, Predicted membrane protein Function unknown 134102938 Common - x-prolyl-dipeptidyl aminopeptidase SACE_6505 37 COG2936 COG2936, Predicted acyl esterases General function prediction only 134102759 Common - peptide ABC transporter peptide-binding protein,putative SACE_6324 190 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 134102489 Common - hypothetical protein SACE_6052 36 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 134102198 Common trpB tryptophan synthase subunit beta SACE_5749 225 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 134099185 Common - KDPG and KHG aldolase SACE_2637 40 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 134101373 Nonpathogen - hypothetical protein SACE_4844 1 None None None 134101894 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase SACE_5392 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134097789 Common pncA pyrazinamidase / nicotinamidase SACE_1199 107 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 134101012 Nonpathogen - hypothetical protein SACE_4479 1 None None None 134101009 Common - multi-domain beta-ketoacyl synthase SACE_4476 207 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 134098358 Common sseA 3-mercaptopyruvate sulfurtransferase SACE_1777 140 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 134099669 Common - hypothetical SAM-dependent methyltransferase SACE_3127 23 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134103628 Common fhbA flavohemoprotein SACE_7206 135 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 134097119 Common thiG thiazole synthase SACE_0508 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 134097635 Common - putative ATP-binding protein involved in chromosome partitioning SACE_1039 228 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 134103293 Common - putative ABC-transporter integral membrane protein SACE_6865 131 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 134098449 Common - hypothetical protein SACE_1873 66 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 134096917 Common - transcriptional regulator, TetR family SACE_0303 5 COG1309 AcrR, Transcriptional regulator Transcription 134102552 Nonpathogen - hypothetical protein SACE_6115 1 None None None 134097155 Nonpathogen - hypothetical protein SACE_0544 1 None None None 134102014 Nonpathogen - hypothetical protein SACE_5564 1 None None None 134099843 Common clpX2 putative Clp protease subunit SACE_3304 34 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 134100197 Common hsp18 heat shock protein SACE_3659 110 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 134102028 Common - glycosyl transferase, family 2 SACE_5578 55 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 134099412 Common rifK 3-amino-5-hydroxybenzoic acid synthase SACE_2870 195 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 134100178 Common - FAD linked oxidase-like SACE_3640 202 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 134102471 Common - hypothetical protein SACE_6033 24 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134102495 Common deaD ATP-dependent RNA helicase SACE_6058 246 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 134100017 Common - TetR-family transcriptional regulator SACE_3479 40 COG1309 AcrR, Transcriptional regulator Transcription 134102611 Common gatC glutamyl-tRNA(Gln) amidotransferase subunit C SACE_6174 138 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 134102618 Nonpathogen - hypothetical protein SACE_6181 1 None None None 134098214 Nonpathogen - hypothetical protein SACE_1631 2 None None None 134100294 Common - erythromycin esterase SACE_3759 68 COG1926 COG1926, Predicted phosphoribosyltransferases General function prediction only 134098124 Common - NADPH-dependent FMN reductase SACE_1538 38 COG0431 COG0431, Predicted flavoprotein General function prediction only 134101407 Common gctA glutaconate CoA-transferase, subunit A SACE_4877 43 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 134103573 Common - transcriptional regulator, TenA/THI-4 family protein, putative SACE_7151 58 COG0819 TenA, Putative transcription activator Transcription 134100601 Common - C4-dicarboxylate transporter/malic acid transport protein SACE_4066 24 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 134100885 Nonpathogen - hypothetical protein SACE_4352 4 None None None 134098275 Common - hypothetical protein SACE_1693 8 None None None 134102560 Common rpmB 50S ribosomal protein L28 SACE_6123 58 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 134097627 Common - LysR-family transcriptional regulator SACE_1031 135 COG0583 LysR, Transcriptional regulator Transcription 134101400 Common - hypothetical protein SACE_4870 12 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 134098179 Common - hypothetical protein SACE_1595 6 COG0433 COG0433, Predicted ATPase General function prediction only 134102636 Common - glycoside hydrolase, family 57 SACE_6199 36 COG1543 COG1543, Uncharacterized conserved protein Function unknown 134096816 Common - glycosyl transferase SACE_0199 12 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 134100211 Common - hypothetical protein SACE_3673 113 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 134096682 Common - amino acid aldolase or racemase-like SACE_0064 15 COG3616 COG3616, Predicted amino acid aldolase or racemase Amino acid transport and metabolism 134098091 Common sigJ RNA polymerase sigma factor SigJ SACE_1505 60 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 134101397 Common - possible transcriptional regulator, ArsR family SACE_4867 27 COG0640 ArsR, Predicted transcriptional regulators Transcription 134100020 Common - dioxygenase SACE_3482 55 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 134102177 Common - protein kinase/transcriptional regulator, LuxR family SACE_5728 98 COG3903 COG3903, Predicted ATPase General function prediction only 134096729 Common - pyridoxamine 5'-phosphate oxidase-related,FMN-binding SACE_0111 12 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 134099340 Common - putative feruloyl-CoA synthetase SACE_2795 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134100962 Common - putative serine/threonine protein kinase SACE_4429 93 COG1262 COG1262, Uncharacterized conserved protein Function unknown 134096759 Common - ECF subfamily sigma factor SACE_0141 133 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 134102006 Common - putative 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase SACE_5556 7 None None None 134102112 Nonpathogen - hypothetical protein SACE_5662 1 None None None 134098683 Common fmt methionyl-tRNA formyltransferase SACE_2113 217 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 134096715 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) SACE_0097 174 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 134101578 Common mtlD mannitol dehydrogenase SACE_5054 90 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 134102239 Common - hypothetical protein SACE_5791 13 None None None 134101073 Common - putative integrase/recombinase SACE_4540 19 None None None 134101919 Nonpathogen - hypothetical protein SACE_5420 1 None None None 134101222 Common - hypothetical protein SACE_4690 123 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134102972 Nonpathogen - hypothetical protein SACE_6540 1 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 134099498 Common cydB cytochrome d ubiquinol oxidase subunit II SACE_2956 12 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 134098004 Common - putative ECF-family RNA polymerase sigma factor SACE_1418 90 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 134102544 Common - possible methyltransferase (methylase) SACE_6107 166 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 134096722 Common - glycosyl transferase SACE_0104 143 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 134101999 Nonpathogen - hypothetical protein SACE_5549 1 None None None 134099035 Nonpathogen copC putative integral membrane protein SACE_2474 3 COG2372 CopC, Uncharacterized protein, homolog of Cu resistance protein CopC General function prediction only 134096985 Common - hypothetical protein SACE_0372 4 None None None 134099750 Nonpathogen - hypothetical protein SACE_3211 1 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 134097532 Common glpX fructose 1,6-bisphosphatase II SACE_0934 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 134099714 Common - putative oxidoreductase SACE_3174 61 COG3967 DltE, Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) Cell envelope biogenesis, outer membrane 134098741 Common - putative ABC transporter ATP-binding protein SACE_2171 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 134097534 Nonpathogen - hypothetical protein SACE_0936 1 None None None 134098023 Common - threonine synthase SACE_1437 132 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 134101992 Common bkdA putative 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) E1-alpha chain SACE_5542 153 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 134096953 Common - inosine-uridine preferring nucleoside hydrolase SACE_0339 86 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 134097301 Common - acetyltransferase, GNAT family SACE_0694 5 None None None 134099501 Nonpathogen - hypothetical protein SACE_2959 1 None None None 134098978 Common uspA3 universal stress protein family SACE_2416 28 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 134100747 Common - putative dehydrogenase related to short-chain alcohol dehydrogenases SACE_4214 202 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 134101739 Common - TrkA-C domain protein SACE_5235 26 COG0490 COG0490, Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels Inorganic ion transport and metabolism 134099246 Common - hypothetical protein SACE_2700 27 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 134102394 Common - hypothetical protein SACE_5947 9 None None None 134098108 Nonpathogen - hypothetical protein SACE_1522 1 None None None 134100004 Common fabH5 3-oxoacyl-ACP synthase III SACE_3466 180 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 134099192 Common - hypothetical protein SACE_2645 55 COG2828 COG2828, Uncharacterized protein conserved in bacteria Function unknown 134102284 Common - short chain dehydrogenase SACE_5836 93 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134101833 Common pkn32 serine/threonine protein kinase SACE_5330 29 COG2319 COG2319, FOG: WD40 repeat General function prediction only 134101115 Common - hypothetical protein SACE_4582 34 COG3777 COG3777, Uncharacterized conserved protein Function unknown 134102331 Common - N-acetylglutamate synthase SACE_5884 63 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 134097853 Common - molybdopterin dehydrogenase, FAD-binding protein SACE_1264 101 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 134103651 Common - hypothetical protein SACE_7229 33 COG3257 GlxB, Uncharacterized protein, possibly involved in glyoxylate utilization General function prediction only 134099451 Common - putative glutamate--cysteine ligase SACE_2909 60 COG2170 COG2170, Uncharacterized conserved protein Function unknown 134098485 Common - L-carnitine dehydratase/bile acid-inducible protein F SACE_1910 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 134101754 Common tlyA putative cytotoxin/hemolysin SACE_5250 130 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 134098986 Common - sodium/potassium-transporting ATPase, alpha subunit SACE_2424 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 134103748 Common - twin-arginine translocation pathway signal SACE_7326 73 COG3211 PhoX, Predicted phosphatase General function prediction only 134096731 Nonpathogen - hypothetical protein SACE_0113 1 None None None 134103439 Nonpathogen - hypothetical protein SACE_7014 1 None None None 134097448 Common - phosphatase, Ppx/GppA family SACE_0843 181 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 134101277 Common - secreted trypsin-like serine protease SACE_4745 26 COG5640 COG5640, Secreted trypsin-like serine protease Posttranslational modification, protein turnover, chaperones 134099580 Common - ABC transporter protein, ATP-binding component SACE_3038 216 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 134096833 Common - putative conserved alanine rich lipoprotein LppW SACE_0216 9 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 134097459 Nonpathogen - hypothetical protein SACE_0854 1 None None None 134097024 Common fepD putative ferrichrome transport system permease protein SACE_0411 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 134101809 Nonpathogen chlB2 hypothetical protein SACE_5306 1 None None None 134098637 Common aroB 3-dehydroquinate synthase SACE_2067 206 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 134100646 Common ehpG putative phenazine antibiotic biosynthesis protein SACE_4112 7 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 134101129 Common - glycoside hydrolase family 2, sugar binding SACE_4596 73 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 134098077 Common - hypothetical protein SACE_1491 9 None None None 134099488 Common - hypothetical protein SACE_2946 4 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 134101970 Nonpathogen - hypothetical protein SACE_5514 1 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 134098193 Common helZ probable helicase, Snf2/Rad54 family SACE_1609 132 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 134099264 Nonpathogen - hypothetical protein SACE_2719 1 None None None 134100045 Common - probable CoB--CoM heterodisulfide reductase SACE_3507 162 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 134100589 Common - oxidoreductase, aldo/keto reductase family SACE_4054 200 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 134102968 Nonpathogen - hypothetical protein SACE_6536 1 None None None 134101748 Common pyrG CTP synthetase SACE_5244 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 134102066 Common - FAD dependent oxidoreductase SACE_5616 181 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 134097883 Nonpathogen - hypothetical protein SACE_1296 1 None None None 134099678 Common - putative endoribonuclease, translation initiation inhibitor SACE_3136 93 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 134102995 Common - hypothetical protein SACE_6563 13 None None None 134099591 Common patB aminotransferase SACE_3049 232 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 134101689 Common - hypothetical protein SACE_5181 40 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 134101442 Common - assimilatory nitrate reductase catalytic subunit SACE_4912 170 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 134097663 Common - alpha/beta hydrolase fold SACE_1067 62 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134101269 Common - putative DedA/PAP2 family phospholipid acid phosphatase SACE_4737 104 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 134096769 Common pheA prephenate dehydratase (PDT) SACE_0152 211 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 134102104 Common - TmrB-like protein SACE_5654 13 None None None 134102252 Common - NUDIX hydrolase SACE_5804 73 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 134102478 Common whiG putative RNA polymerase sigma factor SACE_6040 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 134100334 Common narK nitrite extrusion protein SACE_3799 83 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 134103647 Nonpathogen - hypothetical protein SACE_7225 1 None None None 134099443 Common - hypothetical protein SACE_2901 3 COG5500 COG5500, Predicted integral membrane protein Function unknown 134099647 Common - hypothetical protein SACE_3105 9 None None None 134098455 Common - hypothetical protein SACE_1879 133 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 134102669 Common - hypothetical protein SACE_6232 6 None None None 134099745 Nonpathogen - hypothetical protein SACE_3206 2 None None None 134102939 Common - serine protease precursor SACE_6506 9 None None None 134102243 Common - nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase SACE_5795 189 COG0388 COG0388, Predicted amidohydrolase General function prediction only 134099091 Nonpathogen - hypothetical protein SACE_2535 1 None None None 134097389 Nonpathogen - hypothetical regulator protein SACE_0783 9 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134100901 Nonpathogen - hypothetical protein SACE_4368 1 None None None 134103455 Common - possible phiRv2 prophage protein SACE_7030 7 None None None 134099259 Nonpathogen - hypothetical protein SACE_2714 2 None None None 134097096 Common - hydrolase SACE_0482 9 COG5640 COG5640, Secreted trypsin-like serine protease Posttranslational modification, protein turnover, chaperones 134098465 Nonpathogen - hypothetical protein SACE_1889 1 None None None 134101937 Common - phenylacetic acid degradation-related protein SACE_5438 82 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 134097133 Common - hypothetical protein SACE_0522 19 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 134100329 Common - putative von Willebrand factor, type A SACE_3794 106 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 134103366 Nonpathogen - hypothetical protein SACE_6939 1 None None None 134097916 Common - hypothetical protein SACE_1329 12 COG2311 COG2311, Predicted membrane protein Function unknown 134097442 Common - hypothetical protein SACE_0837 9 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 134102431 Nonpathogen - hypothetical protein SACE_5987 1 None None None 134103760 Common - methyltransferase type 12 SACE_7340 20 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134101019 Common hcaC2 3-phenylpropionate dioxygenase ferredoxin subunit SACE_4486 71 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 134100876 Common adhA7 alcohol dehydrogenase SACE_4343 199 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 134101267 Common - FAD dependent oxidoreductase SACE_4735 106 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 134098665 Nonpathogen - hypothetical protein SACE_2094 1 None None None 134098490 Nonpathogen - major facilitator superfamily MFS_1 SACE_1915 9 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 134103811 Common parA putative chromosome partitioning protein SACE_7391 230 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 134103765 Common - hypothetical protein SACE_7345 5 COG5516 COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding General function prediction only 134097059 Common algI alginate O-acetyltransferase SACE_0446 86 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 134100740 Nonpathogen - hypothetical protein SACE_4207 1 None None None 134100280 Common - enoyl-CoA hydratase SACE_3745 174 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 134096639 Common - putative multi-domain beta-ketoacyl synthase SACE_0021 210 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134096632 Common mmpL10 conserved large membrane protein SACE_0014 57 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 134099361 Nonpathogen - hypothetical protein SACE_2818 1 None None None 134100290 Common - methyltransferase SACE_3755 20 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 134097782 Common mmgA acetyl-CoA acetyltransferase SACE_1192 166 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 134097193 Nonpathogen - hypothetical protein SACE_0583 2 None None None 134101080 Common - transcriptional regulator, DeoR family SACE_4547 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 134098069 Common phoH phosphate starvation-induced protein SACE_1483 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 134098702 Common - transcriptional regulator, Cro/CI family SACE_2132 61 COG1476 COG1476, Predicted transcriptional regulators Transcription 134103463 Common - putative acetyl-CoA carboxylase alpha subunit SACE_7038 234 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 134101926 Common dadA2 D-amino-acid dehydrogenase small subunit SACE_5427 117 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 134099567 Nonpathogen - PE-PGRS family protein SACE_3025 1 None None None 134100940 Common - hypothetical membrane spanning protein SACE_4407 40 COG1434 COG1434, Uncharacterized conserved protein Function unknown 134101660 Common - hypothetical protein SACE_5151 25 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 134098362 Common - protein of unknown function DUF395, YeeE/YedE SACE_1782 47 COG2391 COG2391, Predicted transporter component General function prediction only 134101822 Common - hypothetical protein SACE_5319 5 None None None 134098554 Common - transcriptional regulator, CdaR SACE_1980 43 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 134097717 Common - DNA repair protein RadA domain protein SACE_1122 17 COG3598 RepA, RecA-family ATPase DNA replication, recombination, and repair 134100202 Common - hypothetical protein SACE_3664 4 None None None 134101693 Common mmsA3 methylmalonate-semialdehyde dehydrogenase (acylating) SACE_5185 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 134102408 Common - hypothetical protein SACE_5962 202 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 134101802 Common - D-amino acid deaminase SACE_5299 56 COG3616 COG3616, Predicted amino acid aldolase or racemase Amino acid transport and metabolism 134100230 Common - acetyltransferase, GNAT family SACE_3692 4 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 134096898 Common - probable thioredoxin-disulfide reductase SACE_0284 125 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 134101624 Common - hypothetical protein SACE_5110 4 COG1769 COG1769, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 134101661 Nonpathogen - hypothetical protein SACE_5153 1 None None None 134103755 Common hemK1 methylase of polypeptide chain release factors SACE_7335 112 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 134098827 Nonpathogen - hypothetical protein SACE_2258 1 None None None 134099323 Common acd 1-aminocyclopropane-1-carboxylate deaminase SACE_2778 108 COG2515 Acd, 1-aminocyclopropane-1-carboxylate deaminase Amino acid transport and metabolism 134103509 Nonpathogen - hypothetical protein SACE_7085 1 None None None 134097796 Common cysM cysteine synthase SACE_1206 221 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 134103598 Common - hypothetical protein SACE_7176 14 COG4129 COG4129, Predicted membrane protein Function unknown 134100051 Common pcaG protocatechuate 3,4-dioxygenase alpha chain SACE_3513 47 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 134098581 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, putative SACE_2007 24 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 134102232 Common - magnesium and cobalt efflux protein CorC SACE_5784 217 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 134097382 Common rimJ ribosomal-protein-alanine acetyltransferase SACE_0776 81 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 134097404 Common - transcriptional regulator SACE_0798 11 COG1695 COG1695, Predicted transcriptional regulators Transcription 134099392 Common - probable 3-hydroxyacyl-CoA dehydrogenase protein SACE_2849 29 COG0824 FcbC, Predicted thioesterase General function prediction only 134099212 Common - hypothetical protein SACE_2665 9 None None None 134101153 Common - oxidoreductase, iron-sulphur binding subunit SACE_4620 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 134101283 Nonpathogen - hypothetical protein SACE_4751 1 None None None 134099659 Common - hypothetical protein SACE_3117 2 None None None 134103330 Common nuoA NADH dehydrogenase I chain A SACE_6902 162 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 134098813 Common - tRNA (adenine-N(1)-)-methyltransferase SACE_2244 59 COG2519 GCD14, tRNA(1-methyladenosine) methyltransferase and related methyltransferases Translation, ribosomal structure and biogenesis 134101053 Common - stress-inducible protein SACE_4520 28 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 134100459 Common - hypothetical protein SACE_3924 5 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 134098160 Common cobD cobalamin biosynthesis protein SACE_1574 152 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 134101861 Common - integral membrane protein SACE_5359 7 None None None 134096970 Common - putative hydrolase SACE_0356 9 COG4319 COG4319, Ketosteroid isomerase homolog Function unknown 134100396 Common katE catalase HPII SACE_3861 130 COG0753 KatE, Catalase Inorganic ion transport and metabolism 134098884 Common - transposase SACE_2319 21 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134098201 Common - IS1557, transposase SACE_1617 38 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 134098248 Common - ABC sugar transporter, membrane subunit SACE_1665 161 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 134102672 Nonpathogen - hypothetical protein SACE_6235 2 None None None 134103738 Common - hypothetical protein SACE_7316 5 None None None 134097776 Common - lipoprotein SACE_1186 27 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 134097490 Common - putative inner membrane protein translocase component YidC SACE_0892 206 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 134097296 Common - hypothetical protein SACE_0689 23 COG3162 COG3162, Predicted membrane protein Function unknown 134100303 Common - transcriptional regulator, GntR family SACE_3768 138 COG1802 GntR, Transcriptional regulators Transcription 134102138 Common - protein of unknown function DUF81 SACE_5689 71 COG0730 COG0730, Predicted permeases General function prediction only 134099543 Common - hypothetical protein SACE_3001 86 COG1733 COG1733, Predicted transcriptional regulators Transcription 134100679 Common benE benzoate transporter SACE_4146 59 COG3135 BenE, Uncharacterized protein involved in benzoate metabolism Secondary metabolites biosynthesis, transport, and catabolism 134097166 Common - ABC transporter, permease component SACE_0555 199 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 134101868 Nonpathogen - hypothetical protein SACE_5366 2 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 134096857 Nonpathogen - hypothetical protein SACE_0240a 1 None None None 134098501 Nonpathogen - hypothetical protein SACE_1926 1 None None None 134100239 Common uvrA2 UvrABC system protein A SACE_3701 243 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 134099977 Common - glycosyl transferase, family 39 SACE_3439 6 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 134097060 Nonpathogen comA ComA SACE_0447 10 None None None 134100165 Common - putative transposon tn5714 transposase SACE_3627 47 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134100259 Common - cyclic nucleotide-binding domain (cNMP-BD) protein SACE_3723 25 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 134097865 Common - oligopeptide/dipeptide ABC transporter, permease protein SACE_1276 216 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 134103491 Common - hypothetical protein SACE_7066 13 None None None 134101200 Common katG catalase/peroxidase HPI SACE_4668 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 134096995 Common cpdA cyclic nucleotide phosphodiesterase SACE_0382 86 COG1409 Icc, Predicted phosphohydrolases General function prediction only 134103097 Nonpathogen - surface protein SACE_6667 1 None None None 134102096 Common - alpha/beta hydrolase SACE_5646 10 None None None 134100457 Common - putative transposase SACE_3922 70 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 134103716 Common - pyruvate dehydrogenase E1 component, alpha subunit SACE_7294 154 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 134096778 Common - Cof protein SACE_0161 122 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 134098166 Nonpathogen - hypothetical protein SACE_1580 1 None None None 134099106 Common - putative transposase SACE_2551 51 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 134101778 Nonpathogen - hypothetical protein SACE_5275 3 COG5640 COG5640, Secreted trypsin-like serine protease Posttranslational modification, protein turnover, chaperones 134098990 Common - hypothetical protein SACE_2428 13 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 134099405 Common - coenzyme F420-dependent N(5),N(10)-methylenetetrahydromethanopterin reductase SACE_2863 77 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 134100792 Common - transcriptional regulator, GntR family SACE_4259 121 COG1802 GntR, Transcriptional regulators Transcription 134100947 Common - ABC transporter, ATP-binding component SACE_4414 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 134098071 Common - CBS domain protein SACE_1485 215 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 134097463 Common - hypothetical protein SACE_0859 9 None None None 134102662 Nonpathogen - hypothetical protein SACE_6225 2 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 134103027 Common - possible transcriptional regulator, TetR family SACE_6596 17 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 134101065 Common - heavy metal translocating P-type ATPase SACE_4532 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 134096864 Nonpathogen - hypothetical protein SACE_0248 1 None None None 134103553 Nonpathogen - hypothetical protein SACE_7131 1 None None None 134100159 Common - possible transcriptional regulator SACE_3621 11 COG2345 COG2345, Predicted transcriptional regulator Transcription 134100737 Nonpathogen - hypothetical protein SACE_4204 1 None None None 134098499 Common - hydrolase SACE_1924 51 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134102898 Common - peptidase M50 SACE_6465 73 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 134103444 Nonpathogen - hypothetical protein SACE_7019 1 None None None 134103428 Common - protein of unknown function DUF161 SACE_7002 32 COG2364 COG2364, Predicted membrane protein Function unknown 134100911 Common benB benzoate 1,2-dioxygenase beta subunit SACE_4378 25 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 134098697 Nonpathogen - hypothetical protein SACE_2127 1 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 134097814 Common - two-component system sensor kinase SACE_1224 30 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 134101421 Common - MFS transporter, DHA1 family SACE_4891 14 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134099766 Common - hypothetical protein SACE_3227 30 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 134099996 Common - hypothetical protein SACE_3458 21 COG3662 COG3662, Uncharacterized protein conserved in bacteria Function unknown 134100467 Common - oxidoreductase SACE_3932 42 COG0778 NfnB, Nitroreductase Energy production and conversion 134102085 Common - regulatory protein SACE_5635 11 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 134102720 Common atpF ATP synthase B chain SACE_6284 26 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 134097619 Common folP dihydropteroate synthase SACE_1023 193 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 134096663 Common pknA putative serine/threonine protein kinase SACE_0045 155 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 134099345 Common - 3-hydroxyisobutyrate dehydrogenase, NAD-binding protein SACE_2800 13 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 134096705 Common - hypothetical protein SACE_0087 11 COG2251 COG2251, Predicted nuclease (RecB family) General function prediction only 134097620 Nonpathogen - hypothetical protein SACE_1024 1 None None None 134103677 Common nos nitric oxide synthase oxygenase SACE_7255 11 COG4362 COG4362, Nitric oxide synthase, oxygenase domain Inorganic ion transport and metabolism / Amino acid transport and metabolism 134101721 Common - putative ribose 5-phosphate isomerase SACE_5216 127 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 134096847 Common - putative HTH-type transcriptional regulator SACE_0230 90 COG1309 AcrR, Transcriptional regulator Transcription 134100670 Common - FAD-binding monooxygenase, PheA/TfdB family SACE_4137 123 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 134101071 Common - possible sugar phosphate isomerase/epimerase SACE_4538 45 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 134103432 Common - metal dependent phosphohydrolase SACE_7007 8 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 134098599 Common secD preprotein translocase subunit SecD SACE_2025 155 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 134098709 Common - hypothetical protein SACE_2139 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 134103449 Nonpathogen - hypothetical protein SACE_7024 2 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 134097844 Common ydeS similar to transcriptional regulator (TetR/AcrR family) SACE_1255 45 COG1309 AcrR, Transcriptional regulator Transcription 134101093 Common - O-methyltransferase, family 2 SACE_4560 37 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 134097317 Common - putative IS element transposase SACE_0711 69 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 134097612 Common - hypothetical protein SACE_1016 8 None None None 134097656 Common rhlE putative ATP-dependent RNA helicase SACE_1060 239 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 134102091 Common - GntR-family transcriptional regulator SACE_5641 92 COG1725 COG1725, Predicted transcriptional regulators Transcription 134098616 Common cynT carbonic anhydrase SACE_2046 152 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 134098428 Nonpathogen - hypothetical protein SACE_1852 1 None None None 134103335 Nonpathogen - hypothetical protein SACE_6908 1 None None None 134097689 Common - WhiB-family transcriptional regulator SACE_1093 19 None None None 134100493 Common glpD glycerol-3-phosphate dehydrogenase SACE_3958 152 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 134102929 Nonpathogen - hypothetical protein SACE_6496 2 None None None 134101874 Common - amino acid permease-associated region SACE_5372 124 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 134100072 Common - IclR-family transcriptional regulator SACE_3534 121 COG1414 IclR, Transcriptional regulator Transcription 134097282 Nonpathogen - lipoprotein SACE_0674 5 None None None 134100433 Common metH putative 5-methyltetrahydrofolate:homocysteine S-methyltransferase SACE_3898 179 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 134100481 Nonpathogen - hypothetical protein SACE_3946 1 None None None 134099970 Nonpathogen - hypothetical protein SACE_3431 1 None None None 134102515 Common - transcriptional regulator (LacI family) SACE_6078 128 COG1609 PurR, Transcriptional regulators Transcription 134102373 Common infB translation initiation factor IF-2 SACE_5926 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 134097176 Common - putative bifunctional molybdopterim biosynthesis protein SACE_0565 149 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 134103746 Common ppsII phosphoenolpyruvate synthase SACE_7324 154 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 134096909 Common iniA isoniazid inductible gene protein IniA SACE_0295 26 COG1159 Era, GTPase General function prediction only 134101632 Common - transposase, IS3 family SACE_5120 141 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 134102647 Common - rhodanese-like SACE_6210 67 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 134100517 Nonpathogen - hypothetical protein SACE_3982 1 None None None 134103077 Common - hypothetical protein SACE_6647 39 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 134101686 Common - hydrolase, alpha/beta fold family SACE_5178 22 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134099792 Nonpathogen - hypothetical protein SACE_3253 1 None None None 134101805 Common - putative sugar transport integral membrane protein SACE_5302 80 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 134097289 Common - glycosyl transferase, group 1 SACE_0682 123 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 134101100 Common fabH5 3-oxoacyl-ACP synthase III SACE_4567 172 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 134099020 Common - hypothetical protein SACE_2458 25 None None None 134101846 Nonpathogen - hypothetical protein SACE_5344 1 None None None 134097768 Nonpathogen - hypothetical protein SACE_1178 1 COG4767 VanZ, Glycopeptide antibiotics resistance protein Defense mechanisms 134097667 Common - hypothetical protein SACE_1071 5 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 134100364 Common - secreted tripeptidylaminopeptidase SACE_3829 32 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134101495 Common aglA2 alpha-glucosidase SACE_4966 16 None None None 134096950 Common - putative sodium/proton antiporter SACE_0336 105 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 134097966 Common - transcriptional regulator SACE_1380 128 COG1733 COG1733, Predicted transcriptional regulators Transcription 134102790 Common - putative transport protein SACE_6356 56 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134099075 Common - hypothetical protein SACE_2518 20 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 134098224 Common - OsmC-like protein SACE_1641 41 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 134101368 Common - TetR-family transcriptional regulator SACE_4839 46 COG1309 AcrR, Transcriptional regulator Transcription 134096982 Common - type II secretion system protein SACE_0369 7 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 134103435 Nonpathogen - hypothetical protein SACE_7010 1 None None None 134097219 Nonpathogen - hypothetical protein SACE_0609 1 None None None 134097842 Common dapA4 dihydrodipicolinate synthase SACE_1253 29 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 134103382 Common galE UDP-glucose 4-epimerase SACE_6956 130 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 134101165 Common - amino acid ABC transporter permease protein SACE_4632 140 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 134097010 Common folE GTP cyclohydrolase I SACE_0397 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 134097849 Common guaD guanine deaminase SACE_1260 208 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 134098669 Common mihF putative integration host factor SACE_2099 16 None None None 134102680 Common - hypothetical protein SACE_6243 60 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 134103816 Common rnpA putative RNase P component SACE_7396 15 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 134101813 Common - Dimethyladenosine transferase (rRNA methylation) SACE_5310 7 COG3832 COG3832, Uncharacterized conserved protein Function unknown 134096902 Common - NADPH-dependent FMN reductase family protein SACE_0288 36 COG0431 COG0431, Predicted flavoprotein General function prediction only 134096955 Common ptlR AraC-family transcriptional regulator SACE_0341 140 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 134099257 Common - hypothetical protein SACE_2712 29 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 134099606 Common - hypothetical protein SACE_3064 7 None None None 134100963 Common - putative arabinan endo-1,5-alpha-L-arabinosidase A SACE_4430 35 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 134097237 Common - hypothetical protein SACE_0627 4 None None None 134098386 Common - hypothetical protein SACE_1807 3 COG0756 Dut, dUTPase Nucleotide transport and metabolism 134099176 Common - thioesterase involved in non-ribosomal peptide biosynthesis SACE_2628 49 COG3208 GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 134103563 Nonpathogen - hypothetical protein SACE_7141 4 None None None 134103124 Common - two-component system response regulator SACE_6694 181 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134098999 Common - peptidase M50 SACE_2437 68 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 134103473 Common - 2,5-diketo-D-gluconic acid reductase SACE_7048 186 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 134103075 Common - phosphonate-binding protein SACE_6645 100 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 134101340 Nonpathogen - hypothetical protein SACE_4811 1 None None None 134103020 Common ydeS similar to transcriptional regulator (TetR/AcrR family) SACE_6589 74 COG1309 AcrR, Transcriptional regulator Transcription 134097651 Common - PHP C-terminal domain protein SACE_1055 127 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 134097889 Nonpathogen - hypothetical protein SACE_1302 1 None None None 134098681 Common ggt2 putative gamma-glutamyltranspeptidase SACE_2111 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 134099146 Common - hypothetical protein SACE_2591 11 COG2311 COG2311, Predicted membrane protein Function unknown 134098982 Common - thermophile-specific fructose-1,6-bisphosphatase SACE_2420 37 COG1980 COG1980, Archaeal fructose 1,6-bisphosphatase Carbohydrate transport and metabolism 134103263 Common rplD 50S ribosomal protein L4 SACE_6835 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 134100816 Common penP beta-lactamase precursor SACE_4283 55 COG2367 PenP, Beta-lactamase class A Defense mechanisms 134103467 Common - ABC transporter, ATP binding protein. SACE_7042 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 134100312 Common - transmembrane transport protein SACE_3777 47 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 134102275 Nonpathogen - hypothetical protein SACE_5827 1 None None None 134097244 Common ureA urease gamma subunit protein SACE_0634 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 134101087 Common - oligopeptide ABC transporter (ATP-binding protein) SACE_4554 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 134099837 Common - hypothetical protein SACE_3298 27 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 134097356 Common - Cob(II)yrinic acid a,c-diamide reductase SACE_0750 106 COG0778 NfnB, Nitroreductase Energy production and conversion 134101657 Common - GCN5-related N-acetyltransferase SACE_5148 34 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 134096849 Common - hypothetical protein SACE_0232 7 None None None 134097095 Nonpathogen - hypothetical protein SACE_0481 1 None None None 134102326 Common - hypothetical protein SACE_5879 18 COG1396 HipB, Predicted transcriptional regulators Transcription 134097104 Nonpathogen - hypothetical protein SACE_0491 1 None None None 134100553 Common - carbon monoxide dehydrogenase small chain SACE_4018 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 134096786 Common - hypothetical protein SACE_0169 5 None None None 134097646 Nonpathogen - hypothetical protein SACE_1050 1 None None None 134101596 Common - transposase for IS3508i SACE_5073 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 134097807 Nonpathogen - hypothetical protein SACE_1217 1 None None None 134096820 Common - probable NADPH:quinone reductase SACE_0203 175 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 134101793 Common - dihydroxyacetone kinase, C-terminal domain SACE_5290 75 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 134101302 Nonpathogen - hypothetical protein SACE_4770 2 None None None 134097787 Nonpathogen - hypothetical protein SACE_1197 1 None None None 134100460 Common - hypothetical protein SACE_3925 4 None None None 134102814 Common ald putative L-alanine dehydrogenase SACE_6380 166 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 134097266 Common - IS1647-like transposase SACE_0657 39 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134102474 Common pyrH uridylate kinase SACE_6036 237 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 134096989 Common - hypothetical protein SACE_0376 4 None None None 134101314 Common nha possible sodium/hydrogen antiporter SACE_4782 102 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 134101237 Common - short-chain dehydrogenase/reductase SDR SACE_4705 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134102734 Common thrA homoserine dehydrogenase SACE_6298 188 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 134102143 Common - hypothetical protein SACE_5694 24 None None None 134097851 Common atzB hydroxydechloroatrazine ethylaminohydrolase SACE_1262 167 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 134102608 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B SACE_6171 210 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 134100243 Nonpathogen - branched-chain amino acid binding protein SACE_3707 4 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 134098872 Common - hypothetical protein SACE_2307 41 COG1041 COG1041, Predicted DNA modification methylase DNA replication, recombination, and repair 134097345 Nonpathogen - hypothetical protein SACE_0739 1 None None None 134103289 Common mce5C putative Mce family protein SACE_6861 19 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 134099768 Common - hypothetical protein SACE_3229 9 COG3503 COG3503, Predicted membrane protein Function unknown 134100118 Common fadE25 acyl-CoA dehydrogenase SACE_3580 168 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134098767 Common - hypothetical protein SACE_2197 2 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 134097733 Nonpathogen - hypothetical protein SACE_1138 1 None None None 134096949 Common - protein of unknown function DUF1469 SACE_0335 14 None None None 134099492 Common clpC putative ATP-dependent Clp protease SACE_2950 226 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 134099626 Common echA5 enoyl-CoA hydratase SACE_3084 145 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 134102581 Common leuC 3-isopropylmalate dehydratase large subunit SACE_6144 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 134102031 Common - NAD-dependent epimerase/dehydratase SACE_5581 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 134101106 Common - putative IS200-like transposase SACE_4573 74 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 134101612 Common - transposase SACE_5091 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 134098728 Common pgiA glucose-6-phosphate isomerase SACE_2158 89 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 134097772 Common - haloacid dehalogenase-like hydrolase SACE_1182 23 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 134102335 Nonpathogen - bifunctional protein (secreted sugar binding protein/sugar hydrolase) SACE_5888 2 None None None 134098421 Common msrB peptide methionine sulfoxide reductase SACE_1845 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 134099734 Common - hypothetical protein SACE_3195 12 None None None 134102511 Nonpathogen - hypothetical protein SACE_6074 1 None None None 134101852 Common - transcriptional regulator, MerR family SACE_5350 10 COG0789 SoxR, Predicted transcriptional regulators Transcription 134098250 Common malR maltose operon transcriptional repressor SACE_1667 126 COG1609 PurR, Transcriptional regulators Transcription 134103154 Common rimI ribosomal-protein-alanine N-acetyltransferase SACE_6724 182 COG0456 RimI, Acetyltransferases General function prediction only 134100093 Common - possible metal-dependent hydrolase SACE_3555 26 COG3687 COG3687, Predicted metal-dependent hydrolase General function prediction only 134102157 Common - transcriptional regulator, GntR family SACE_5708 128 COG2186 FadR, Transcriptional regulators Transcription 134097414 Common pks16 acyl-CoA synthetase SACE_0809 210 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134099579 Common - putative ABC transporter transmembrane SACE_3037 245 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 134101288 Common acoC branched-chain alpha-keto acid dehydrogenase subunit E2 SACE_4756 203 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134099805 Common - multidrug resistance transporter, MFS superfamily SACE_3266 135 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134102151 Common glyA2 serine hydroxymethyltransferase SACE_5702 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 134101958 Nonpathogen - hypothetical protein SACE_5460 4 None None None 134096622 Common dnaN DNA polymerase III subunit beta SACE_0003 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 134097566 Common gvpJ gas vesicle protein SACE_0970 22 None None None 134101974 Common - ATP/GTP binding protein SACE_5518 167 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 134102700 Common - putative multiple sugar transport system permease protein SACE_6264 142 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 134101120 Common - transcriptional regulator, LysR family SACE_4587 175 COG0583 LysR, Transcriptional regulator Transcription 134102503 Common ftsY signal recognition particle GTPase SACE_6066 246 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 134103195 Common - hputative ribokinase SACE_6765 209 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 134100535 Common - transposase, IS891/IS1136/IS1341 SACE_4000 75 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 134099507 Common dhlB haloacid dehalogenase-like hydrolase SACE_2965 37 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 134099318 Common - similar to Enoyl-CoA hydratase/isomerase SACE_2773 35 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134103134 Common - hypothetical protein SACE_6704 20 None None None 134103641 Common - hypothetical protein SACE_7219 4 None None None 134098435 Common - protein of unknown function DUF1503 SACE_1859 9 None None None 134102699 Common - ABC sugar transporter, permease component SACE_6263 166 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 134099044 Common - glycoside hydrolase 15-related SACE_2487 72 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 134101836 Common - LysR-family transcriptional regulator SACE_5334 150 COG0583 LysR, Transcriptional regulator Transcription 134097184 Common - HAD-superfamily hydrolase, subfamily IIA SACE_0574 104 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 134102455 Common speB agmatinase SACE_6017 156 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 134102891 Common - hypothetical protein SACE_6458 12 None None None 134103422 Common - hypothetical protein SACE_6996 10 COG4995 COG4995, Uncharacterized protein conserved in bacteria Function unknown 134098705 Common - transcriptional regulator, DeoR family SACE_2135 115 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 134100755 Common - hypothetical protein SACE_4222 3 None None None 134097674 Common - probable ATP-dependent DNA helicase SACE_1078 226 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 134099776 Common - integral membrane protein SACE_3237 27 COG3247 HdeD, Uncharacterized conserved protein Function unknown 134099586 Common - DNA-binding protein SACE_3044 13 None None None 134097869 Common nrdB ribonucleotide-diphosphate reductase subunit beta SACE_1282 156 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 134100407 Common - cold-shock DNA-binding domain protein SACE_3872 181 COG1278 CspC, Cold shock proteins Transcription 134102366 Common - hypothetical protein SACE_5919 241 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 134100279 Common - protein of unknown function DUF112,transmembrane SACE_3744 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 134100076 Nonpathogen - hypothetical protein SACE_3538 1 None None None 134099596 Common paaL Na(+):solute symporter, SSF family SACE_3054 118 COG4147 DhlC, Predicted symporter General function prediction only 134096782 Common glf UDP-galactopyranose mutase SACE_0165 56 COG0562 Glf, UDP-galactopyranose mutase Cell envelope biogenesis, outer membrane 134098592 Common - protein of unknown function DUF28 SACE_2018 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 134097913 Common - thioesterase family protein SACE_1326 16 COG0824 FcbC, Predicted thioesterase General function prediction only 134097230 Common - putative iron ABC transporter binding protein SACE_0620 129 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 134102904 Nonpathogen vrrB hypervariable Bacillus group-specific protein SACE_6471 1 None None None 134097043 Common - ABC transporter ATP-binding protein SACE_0430 51 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 134097143 Common - hypothetical protein SACE_0532 3 None None None 134100447 Common - two-component system response regulator SACE_3912 172 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134100959 Common - hypothetical protein SACE_4426 6 COG2353 COG2353, Uncharacterized conserved protein Function unknown 134101576 Nonpathogen - hypothetical protein SACE_5052 2 None None None 134099575 Common - putative peptide monooxygenase SACE_3033 52 COG3486 IucD, Lysine/ornithine N-monooxygenase Secondary metabolites biosynthesis, transport, and catabolism 134099476 Common - transcriptional regulator SACE_2934 11 COG3629 DnrI, DNA-binding transcriptional activator of the SARP family Signal transduction mechanisms 134097750 Common cyp23 putative cytochrome P450 SACE_1158 85 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134099565 Common tnp9B transposase, IS4 family SACE_3023 23 None None None 134101067 Common - transposase SACE_4534 64 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134098869 Nonpathogen - hypothetical protein SACE_2303 2 None None None 134102982 Common - hypothetical protein SACE_6550 28 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 134098055 Nonpathogen - hypothetical protein SACE_1469 1 None None None 134096911 Common - monooxygenase, FAD-binding SACE_0297 88 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 134098379 Nonpathogen - hypothetical protein SACE_1800 6 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 134097833 Common - transcriptional regulator SACE_1244 112 COG1733 COG1733, Predicted transcriptional regulators Transcription 134098230 Common - hypothetical protein SACE_1647 41 None None None 134103389 Nonpathogen - hypothetical protein SACE_6963 1 COG5373 COG5373, Predicted membrane protein Function unknown 134096760 Common - putative cytochrome ubiquinol oxidase subunit SACE_0142 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 134101234 Common dadA2 D-amino-acid dehydrogenase small subunit SACE_4702 124 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 134100951 Common - putative transcriptional regulator SACE_4418 10 COG1309 AcrR, Transcriptional regulator Transcription 134101601 Common - transcriptional regulator (LuxR/UhpA family) SACE_5078 78 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134102584 Common - haloacid dehalogenase-like hydrolase family protein SACE_6147 160 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 134101726 Common - DeoR family transcriptional regulator of sugar metabolism SACE_5221 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 134100101 Common - 4Fe-4S ferredoxin, iron-sulfur binding protein SACE_3563 164 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 134099127 Common - TetR family transcriptional regulator SACE_2572 34 COG1309 AcrR, Transcriptional regulator Transcription 134102078 Common - hypothetical protein SACE_5628 8 None None None 134101508 Common - hypothetical protein SACE_4980 118 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 134102340 Common - hypothetical protein SACE_5893 2 None None None 134097421 Common prsA ribose-phosphate pyrophosphokinase SACE_0816 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 134098856 Common ppmB putative polyprenol phosphate mannosyl transferase 2 SACE_2288 133 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 134100794 Common glcD (S)-2-hydroxy-acid oxidase, subunit D SACE_4261 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 134102449 Nonpathogen - hypothetical protein SACE_6005 1 None None None 134102569 Common - hypothetical protein SACE_6132 32 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 134100163 Nonpathogen - hypothetical protein SACE_3625 1 COG3231 Aph, Aminoglycoside phosphotransferase Translation, ribosomal structure and biogenesis 134097971 Nonpathogen - hypothetical protein SACE_1385 2 COG4454 COG4454, Uncharacterized copper-binding protein Inorganic ion transport and metabolism 134097199 Nonpathogen - hypothetical protein SACE_0589 2 None None None 134097818 Common indA pigment biosynthetic protein SACE_1229 49 COG2313 IndA, Uncharacterized enzyme involved in pigment biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 134097836 Common bglC3 putative beta-glucosidase SACE_1247 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 134102360 Common pepR putative zinc protease SACE_5913 200 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 134102596 Common ilvB acetolactate synthase 1 catalytic subunit SACE_6159 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 134099683 Common - transcriptional regulator, LysR family SACE_3141 159 COG0583 LysR, Transcriptional regulator Transcription 134099598 Common - probable beta lactamase SACE_3056 58 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 134099067 Nonpathogen - hypothetical protein SACE_2510 1 None None None 134102046 Nonpathogen - hypothetical protein SACE_5596 1 None None None 134098897 Common - transposase SACE_2333 28 COG5659 COG5659, FOG: Transposase DNA replication, recombination, and repair 134102911 Common - protein of unknown function DUF574 SACE_6478 12 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 134097352 Common - transposase SACE_0746 97 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 134098035 Common aceA isocitrate lyase SACE_1449 128 COG2224 AceA, Isocitrate lyase Energy production and conversion 134101896 Common chiA chinitase A precursor SACE_5394 21 COG3469 COG3469, Chitinase Carbohydrate transport and metabolism 134102775 Common - bifunctional deaminase-reductase domain protein SACE_6341 37 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 134102708 Nonpathogen - hypothetical protein SACE_6272 4 None None None 134102310 Common gsmT probable glycine-sarcosine methyltransferase SACE_5862 24 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134098579 Common - histidine triad (HIT) protein SACE_2005 146 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 134102878 Common - hypothetical protein SACE_6444 8 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 134103724 Common - MaoC-like dehydratase SACE_7302 28 COG2030 MaoC, Acyl dehydratase Lipid metabolism 134097568 Nonpathogen - hypothetical protein SACE_0972 5 None None None 134097249 Common ureD putative urease accessory protein SACE_0639 20 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 134097927 Common - DsbA oxidoreductase SACE_1340 16 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 134102387 Common - hypothetical protein SACE_5940 18 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 134102412 Common - GCN5-related N-acetyltransferase SACE_5966 97 COG2153 ElaA, Predicted acyltransferase General function prediction only 134096871 Common - hypothetical protein SACE_0256 12 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 134097432 Common - choline/carnitine/betaine transporter family protein SACE_0827 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 134098390 Common trkA trk system potassium uptake protein SACE_1811 168 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 134097800 Common - beta-lactamase-like SACE_1210 100 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 134097901 Common - hypothetical protein SACE_1314 2 None None None 134101047 Common - ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenase SACE_4514 87 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 134100634 Common - hypothetical protein SACE_4100 24 COG3826 COG3826, Uncharacterized protein conserved in bacteria Function unknown 134098005 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase SACE_1419 142 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 134101951 Common lacG ABC transporter sugar permease SACE_5453 149 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 134098481 Common - transcriptional regulator, TetR family SACE_1906 75 COG1309 AcrR, Transcriptional regulator Transcription 134098354 Common - hypothetical protein SACE_1773 9 None None None 134101609 Common - hypothetical protein SACE_5088 3 None None None 134099102 Common - Mn(2+) transport protein, NramP family SACE_2547 86 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 134102863 Common - possible anti-sigma factor SACE_6429 12 None None None 134103361 Common - phosphoglycerate mutase SACE_6934 27 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 134098155 Common - acetyltransferase SACE_1569 30 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 134099645 Common dnaK 70 kD heat shock protein (molecular chaperone) SACE_3103 234 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 134100388 Common dhbE 2,3-dihydroxybenzoate-AMP ligase SACE_3853 220 COG1021 EntE, Peptide arylation enzymes Secondary metabolites biosynthesis, transport, and catabolism 134103189 Nonpathogen - hypothetical protein SACE_6759 1 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 134101717 Common - Glyoxalase/bleomycin resistance protein/dioxygenase SACE_5212 22 None None None 134100007 Common - PadR-like family transcriptional regulator SACE_3469 31 COG1695 COG1695, Predicted transcriptional regulators Transcription 134102220 Common - transcriptional regulator, ArsR family SACE_5771 88 COG0640 ArsR, Predicted transcriptional regulators Transcription 134099951 Common - possible potassium uptake channel SACE_3412 11 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 134099308 Common - probable multidrug efflux transport protein SACE_2763 188 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134100047 Common pcaR transcriptional regulator, IclR family SACE_3509 121 COG1414 IclR, Transcriptional regulator Transcription 134099922 Common - putative hydrolase/lactonase SACE_3383 34 COG4257 Vgb, Streptogramin lyase Defense mechanisms 134099703 Nonpathogen - hypothetical protein SACE_3162 7 None None None 134101226 Common - transcriptional regulator, XRE family SACE_4694 41 None None None 134097221 Common - transcriptional regulator, MarR family SACE_0611 69 COG1846 MarR, Transcriptional regulators Transcription 134102134 Common - vitamin K epoxide reductase SACE_5684 18 COG4243 COG4243, Predicted membrane protein Function unknown 134099930 Common - transcriptional regulator, GntR family SACE_3391 143 COG1802 GntR, Transcriptional regulators Transcription 134097820 Common ybeK putative tRNA synthetase SACE_1231 89 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 134101643 Common - IS630 family transposase SACE_5133 44 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 134102467 Common - ABC transporter component, possibly Mn transport SACE_6029 185 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 134102872 Common - hypothetical protein SACE_6438 10 None None None 134098515 Common lacZ2 beta-D-galactosidase protein SACE_1940 70 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 134098375 Common - type III restriction enzyme, res subunit SACE_1795 38 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 134100777 Nonpathogen - hypothetical protein SACE_4244 1 None None None 134097397 Common - glycosyl transferase, family 39 SACE_0791 32 COG1928 PMT1, Dolichyl-phosphate-mannose--protein O-mannosyl transferase Posttranslational modification, protein turnover, chaperones 134097595 Common - hypothetical protein SACE_0999 9 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 134101173 Common - hypothetical protein SACE_4640 88 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 134100145 Common masA enolase-phosphatase E-1 SACE_3607 31 COG4229 COG4229, Predicted enolase-phosphatase Energy production and conversion 134097524 Common - binding-protein-dependent transport systems membrane component SACE_0926 201 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 134102023 Common - glycosyl transferase, family 9 SACE_5573 50 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 134097757 Common - hypothetical protein SACE_1165 4 None None None 134100688 Nonpathogen - hypothetical protein SACE_4155 1 None None None 134100500 Common - putative ABC transporter ATP-binding protein SACE_3965 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 134098752 Common - putative sugar hydrolase precursor SACE_2182 26 COG3537 COG3537, Putative alpha-1,2-mannosidase Carbohydrate transport and metabolism 134102490 Common rpsP 30S ribosomal protein S16 SACE_6053 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 134096937 Common - hypothetical protein SACE_0323 11 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 134099292 Common - probable oxidoreductase, short chain dehydrogenase/reductase family SACE_2747 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134103657 Common - metal-dependent phosphohydrolase, HD region SACE_7235 41 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 134098516 Nonpathogen - hypothetical protein SACE_1941 1 None None None 134102105 Nonpathogen - hypothetical protein SACE_5655 1 None None None 134102572 Nonpathogen - hypothetical protein SACE_6135 1 None None None 134098416 Common - transcriptional regulator, MarR family SACE_1840 21 COG1846 MarR, Transcriptional regulators Transcription 134099422 Common - hypothetical protein SACE_2880 8 None None None 134101365 Common - IS1647-like transposase SACE_4836 34 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134101051 Common - hypothetical protein SACE_4518 23 None None None 134103087 Nonpathogen - hypothetical protein SACE_6657 1 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 134096889 Nonpathogen - hypothetical protein SACE_0275 1 None None None 134097875 Common - hypothetical protein SACE_1288 12 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 134101058 Common - permease, cytosine/purines, uracil, thiamine,allantoin family SACE_4525 66 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 134098845 Common - phosphocarrier, HPr family SACE_2276 57 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 134098782 Common - beta-lactamase SACE_2212 135 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 134103002 Common - hypothetical protein SACE_6570 5 None None None 134103606 Common nagA putative N-acetylglucosamine-6-phosphate deacetylase SACE_7184 118 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 134103671 Common - two-component system response regulator SACE_7249 175 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134103378 Common serB phosphoserine phosphatase SACE_6952 76 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 134100648 Common aroH phospho-2-dehydro-3-deoxyheptonate aldolase SACE_4114 73 COG3200 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 134102679 Common - alpha/beta hydrolase fold SACE_6242 172 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134101964 Nonpathogen - hypothetical protein SACE_5482 1 None None None 134102062 Common soxA sarcosine oxidase (alpha subunit) oxidoreductase protein SACE_5612 182 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 134102182 Common - possible glycosyltransferase SACE_5733 18 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 134098911 Common rubS transcriptional regulator SACE_2347 16 COG3629 DnrI, DNA-binding transcriptional activator of the SARP family Signal transduction mechanisms 134100270 Common - alcohol dehydrogenase, zinc-binding SACE_3735 167 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 134097407 Common - transglycosylase-like protein SACE_0801 27 COG3583 COG3583, Uncharacterized protein conserved in bacteria Function unknown 134098797 Nonpathogen - probable multidrug resistance transporter, MFS superfamily SACE_2228 1 None None None 134100862 Common hopC squalene/phytoene dehydrogenase SACE_4329 58 COG3349 COG3349, Uncharacterized conserved protein Function unknown 134102953 Nonpathogen - hypothetical protein SACE_6520 1 None None None 134099955 Common - FAD dependent oxidoreductase SACE_3416 83 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 134100668 Common - MaoC-like dehydratase SACE_4135 14 COG2030 MaoC, Acyl dehydratase Lipid metabolism 134102884 Common sahH S-adenosyl-L-homocysteine hydrolase SACE_6450 177 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 134103785 Common - GGDEF SACE_7365 142 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 134100697 Common - transcriptional regulator, DeoR family SACE_4164 64 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 134102440 Common - hypothetical protein SACE_5996 5 None None None 134097073 Common - hypothetical protein SACE_0460 9 None None None 134097005 Common - hypothetical protein SACE_0392 92 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 134101960 Nonpathogen - hypothetical protein SACE_5462 1 None None None 134101336 Nonpathogen - hypothetical protein SACE_4807 1 None None None 134103216 Nonpathogen - hypothetical protein SACE_6787 1 None None None 134101563 Common tesB acyl-CoA thioesterase II SACE_5039 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 134102480 Common - DNA processing chain A SACE_6043 209 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 134102547 Common - transcriptional regulator, TetR/AcrR family SACE_6110 61 COG1309 AcrR, Transcriptional regulator Transcription 134100690 Nonpathogen - hypothetical protein SACE_4157 1 None None None 134098966 Nonpathogen - phosphopantetheine-binding SACE_2404 8 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134102579 Common - histone-like DNA binding protein SACE_6142 185 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 134098129 Common - putative N-acetylglucosaminylphosphatidylinositol deacetylase SACE_1543 35 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 134102962 Common - carbohydrate kinase, FGGY SACE_6529 155 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 134099929 Common - hypothetical protein SACE_3390 12 COG4639 COG4639, Predicted kinase General function prediction only 134103025 Common fbiC FO synthase SACE_6594 88 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 134100436 Common - glycine sarcosine N-methyltransferase SACE_3901 146 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 134096987 Nonpathogen - hypothetical protein SACE_0374 1 None None None 134103056 Common - two component system response regulator SACE_6626 196 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134100732 Nonpathogen - hypothetical protein SACE_4199 2 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 134097578 Common - ABC transporter integral membrane protein SACE_0982 148 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 134099935 Common - transcriptional regulator, TetR family SACE_3396 12 COG1309 AcrR, Transcriptional regulator Transcription 134102849 Common - malate dehydrogenase (oxaloacetate decarboxylating) SACE_6415 192 COG0281 SfcA, Malic enzyme Energy production and conversion 134098537 Common - hypothetical protein SACE_1963 107 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 134102536 Common mutM,fpg formamidopyrimidine-DNA glycosylase SACE_6099 180 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 134099919 Common - UspA SACE_3380 17 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 134099276 Nonpathogen - hypothetical protein SACE_2731 2 None None None 134096745 Common - hypothetical protein SACE_0127 8 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 134097315 Nonpathogen - hypothetical protein SACE_0708 1 None None None 134098806 Common hisE phosphoribosyl-ATP pyrophosphatase SACE_2237 54 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 134103489 Common - integral membrane protein SACE_7064 6 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 134101006 Common - hypothetical protein SACE_4473 208 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 134103692 Nonpathogen - hypothetical protein SACE_7270 2 None None None 134103613 Common - possible secreted protein SACE_7191 5 None None None 134099542 Common iolE2 sugar phosphate isomerase/epimerase SACE_3000 46 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 134102186 Common - hypothetical protein SACE_5737 16 COG2378 COG2378, Predicted transcriptional regulator Transcription 134102565 Common - putative transcriptional regulator, AsnC family SACE_6128 10 COG1522 Lrp, Transcriptional regulators Transcription 134103190 Common - hypothetical protein SACE_6760 13 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 134102313 Common - hypothetical protein SACE_5865 5 None None None 134103066 Common - isocitrate dehydrogenase SACE_6636 85 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 134103221 Common - integral membrane protein SACE_6793 7 None None None 134097976 Common - transmembrane drug/metabolite transporter family protein SACE_1390 46 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 134098043 Common - acyl-CoA dehydrogenase-like SACE_1457 163 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134103371 Common hemD uroporphyrinogen III synthase/methyltransferase SACE_6944 205 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 134096947 Common - NUDIX hydrolase SACE_0333 81 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 134097478 Common - hypothetical protein SACE_0878 8 COG5483 COG5483, Uncharacterized conserved protein Function unknown 134096802 Common - hypothetical protein SACE_0185 11 COG5479 COG5479, Uncharacterized protein potentially involved in peptidoglycan biosynthesis Cell envelope biogenesis, outer membrane 134103316 Common - polyprenyl diphosphate synthase component SACE_6888 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 134100659 Common - AMP-dependent synthetase and ligase SACE_4126 212 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134100878 Common - hypothetical protein SACE_4345 10 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 134098745 Common sufD FeS assembly protein SACE_2175 172 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 134101942 Common - glucose-methanol-choline oxidoreductase SACE_5444 88 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 134099195 Common - LysR-family transcriptional regulator SACE_2648 167 COG0583 LysR, Transcriptional regulator Transcription 134096812 Common - probable FAD linked oxidoreductase SACE_0195 64 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 134099388 Nonpathogen - hypothetical protein SACE_2845 1 None None None 134100487 Common pdhA2 pyruvate dehydrogenase E1 component alpha subunit SACE_3952 160 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 134098296 Common - geranylgeranyl pyrophosphate synthase SACE_1714 230 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 134099009 Common - beta-phosphoglucomutase hydrolase SACE_2447 152 COG1877 OtsB, Trehalose-6-phosphatase Carbohydrate transport and metabolism 134099883 Common - two-component system sensor kinase SACE_3344 209 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 134101783 Common rpmI 50S ribosomal protein L35 SACE_5280 180 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 134098524 Common - hypothetical protein SACE_1949 6 COG1950 COG1950, Predicted membrane protein Function unknown 134100098 Common selD selenide, water dikinase SACE_3560 120 COG0709 SelD, Selenophosphate synthase Amino acid transport and metabolism 134101528 Common dnaK 70 kD heat shock protein (molecular chaperone) SACE_5000 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 134100641 Common - putative helicase SACE_4107 32 COG3973 COG3973, Superfamily I DNA and RNA helicases General function prediction only 134100063 Common - cytochrome P450 CYP125 SACE_3525 81 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134101023 Common - NAD/factor-dependent formaldehyde dehydrogenase SACE_4490 193 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 134102294 Nonpathogen - hypothetical protein SACE_5846 1 None None None 134098917 Common - transcriptional regulator, CdaR SACE_2353 18 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 134101514 Nonpathogen - hypothetical protein SACE_4986 1 None None None 134099903 Common - hypothetical protein SACE_3364 16 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 134098622 Common alaS alanyl-tRNA synthetase SACE_2052 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 134097603 Common - threonine synthase homolog SACE_1007 111 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 134099757 Common - predicted acyl-CoA transferase/carnitine dehydratase SACE_3218 112 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 134099056 Common - ATP-dependent DNA ligase SACE_2499 63 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 134101798 Common atpB ATP synthase A chain SACE_5295 149 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 134100605 Common narG nitrate reductase alpha chain SACE_4070 127 COG5013 NarG, Nitrate reductase alpha subunit Energy production and conversion 134096793 Nonpathogen - hypothetical protein SACE_0176 1 None None None 134097543 Nonpathogen - hypothetical protein SACE_0945 1 None None None 134102194 Common - iron ABC transporter ATP-binding protein SACE_5745 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 134103009 Common - putative sugar ABC transporter integral membrane protein SACE_6577 107 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 134099098 Common pnbA putative para-nitrobenzyl esterase SACE_2543 53 COG2272 PnbA, Carboxylesterase type B Lipid metabolism 134097390 Common lat L-lysine aminotransferase SACE_0784 236 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 134097860 Common rbsK ribokinase SACE_1271 121 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 134098010 Common proA gamma-glutamyl phosphate reductase SACE_1424 198 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 134096647 Common - RNA polymerase sigma factor SACE_0029 25 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 134103301 Common - probable protein translocation complex preprotein translocase subunit SACE_6873 8 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 134099732 Common - ABC-type antimicrobial peptide transporter,permease component SACE_3193 46 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 134099334 Common - acetylornithine aminotransferase SACE_2789 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 134100990 Nonpathogen - hypothetical protein SACE_4457 1 None None None 134101831 Common - hypothetical protein SACE_5328 12 None None None 134100527 Common - transcriptional regulator, LysR family SACE_3992 188 COG0583 LysR, Transcriptional regulator Transcription 134096800 Nonpathogen - hypothetical protein SACE_0183 1 COG4907 COG4907, Predicted membrane protein Function unknown 134097732 Nonpathogen - hypothetical protein SACE_1137 1 None None None 134098056 Common - PilT protein-like SACE_1470 3 None None None 134099878 Common - putative SAM-dependent methyltransferase SACE_3339 7 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 134097325 Common eryBV 6-DEB TDP-mycarosyl glycosyltransferase SACE_0719 42 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 134098246 Common - exo-alpha-sialidase SACE_1663 17 COG4409 NanH, Neuraminidase (sialidase) Carbohydrate transport and metabolism 134100855 Common - hypothetical protein SACE_4322 32 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 134098907 Common - modular polyketide synthase SACE_2343 209 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134097294 Common - transposase for IS3517 SACE_0687 12 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 134100998 Nonpathogen - hypothetical protein SACE_4465 1 None None None 134099691 Common - FAD dependent oxidoreductase SACE_3149 183 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 134101347 Common cypA cytochrome P450-like enzyme SACE_4818 65 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134103806 Common cwlM N-acetylmuramoyl-L-alanine amidase SACE_7386 132 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 134099527 Common - oxidoreductase domain protein SACE_2985 154 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 134102859 Common - diacylglycerol kinase, catalytic region SACE_6425 98 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 134099262 Nonpathogen - hypothetical protein SACE_2717 1 None None None 134103358 Common - possible cytochrome c biogenesis membrane protein SACE_6931 25 COG1333 ResB, ResB protein required for cytochrome c biosynthesis Posttranslational modification, protein turnover, chaperones 134103253 Common rplX 50S ribosomal protein L24 SACE_6825 212 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 134098492 Common - protein of unknown function DUF574 SACE_1917 13 None None None 134098015 Common - glyoxalase/bleomycin resistance protein/dioxygenase SACE_1429 28 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 134099434 Common ebrB multidrug resistance efflux protein SACE_2892 59 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134098120 Common ahpE member of AhpC/TSA family SACE_1534 222 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 134098848 Common - putative AsnC-family transcriptional regulator (partial) SACE_2280 153 COG1522 Lrp, Transcriptional regulators Transcription 134101403 Common - ferredoxin:(2Fe-2S)-binding SACE_4873 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 134099398 Common - Putative Bacterial Heroin Esterase, Chain A SACE_2855 109 COG0657 Aes, Esterase/lipase Lipid metabolism 134100593 Nonpathogen - hypothetical protein SACE_4058 1 None None None 134097920 Common - prolyl oligopeptidase SACE_1333 115 COG1505 COG1505, Serine proteases of the peptidase family S9A Amino acid transport and metabolism 134102283 Common ftsZ cell division GTPase SACE_5835 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 134098892 Common - L-carnitine dehydratase/bile acid-inducible protein F SACE_2328 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 134102993 Common - FAD-binding monooxygenase, PheA/TfdB family SACE_6561 79 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 134097745 Common cyp18 cytochrome P450 hydroxylase SACE_1153 56 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134098811 Common - putative RecB family exonuclease SACE_2242 30 COG2887 COG2887, RecB family exonuclease DNA replication, recombination, and repair 134098658 Common - putative 3-polyprenyl-4-hydroxybenzoate decarboxylase SACE_2087 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 134100377 Common gcvP1 glycine dehydrogenase SACE_3842 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 134100193 Common - possible tyrosine recombinase SACE_3655 4 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 134102803 Common - long-chain-acyl-CoA dehydrogenase SACE_6369 163 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134103270 Nonpathogen - hypothetical protein SACE_6842 1 None None None 134103631 Common grpE heat shock protein (HSP-70 cofactor) SACE_7209 223 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 134096999 Nonpathogen - hypothetical protein SACE_0386 1 None None None 134098640 Common - glycosyl hydrolase (secreted protein) SACE_2070 11 None None None 134099171 Common - transposase, IS4 SACE_2623 46 None None None 134099869 Common - NUDIX hydrolase SACE_3330 116 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 134100140 Common - hypothetical protein SACE_3602 11 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 134101663 Common - binding-protein-dependent transport permease SACE_5155 148 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 134102120 Common - hypothetical protein SACE_5670 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 134100249 Common - glyoxalase/bleomycin resistance protein/dioxygenase SACE_3713 38 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 134102397 Common cobK precorrin-6A reductase SACE_5950 66 COG2099 CobK, Precorrin-6x reductase Coenzyme metabolism 134098063 Common - coproporphyrinogen III oxidase SACE_1477 204 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 134098203 Common glnE glutamate--ammonia-ligase adenylyltransferase SACE_1619 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 134099986 Common - phosphoglycerate mutase family protein SACE_3448 142 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 134096750 Common - abortive infection protein SACE_0132 16 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 134099862 Common - hypothetical protein SACE_3323 3 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 134102437 Common - PDZ/DHR/GLGF SACE_5993 210 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 134097252 Common - probable multidrug resistance transporter, MFS superfamily SACE_0642 80 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134100663 Common - hypothetical protein SACE_4130 4 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 134102000 Nonpathogen - hypothetical protein SACE_5550 1 None None None 134101254 Nonpathogen - hypothetical protein SACE_4722 1 None None None 134098351 Nonpathogen - membrane protein SACE_1770 1 None None None 134097899 Common ctaB protoheme IX farnesyltransferase SACE_1312 169 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 134102936 Common - putative TetR-family transcriptional regulator SACE_6503 64 COG1309 AcrR, Transcriptional regulator Transcription 134098900 Common - DNA polymerase III alpha subunit (fragment) SACE_2336 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 134098268 Common qcrC cytochrome c mono-and diheme variants SACE_1685 38 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 134100938 Nonpathogen - hypothetical protein SACE_4405 1 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 134103248 Common rplR 50S ribosomal protein L18 SACE_6820 215 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 134099356 Nonpathogen - hypothetical protein-Anti-anti-sigma regulatory factor SACE_2813 1 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 134099037 Common - phthalate 4,5-dioxygenase reductase subunit SACE_2477 109 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 134096930 Common - putative anion-transporting ATPase SACE_0316 25 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 134101409 Common - ABC transporter substrate-binding protein SACE_4879 122 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 134097985 Nonpathogen - hypothetical protein SACE_1399 1 None None None 134098649 Common - pyrimidine operon attenuation protein / uracil phosphoribosyltransferase SACE_2078 109 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 134101768 Common - AsnC-family transcriptional regulator SACE_5264 60 COG1522 Lrp, Transcriptional regulators Transcription 134096795 Common embC probable arabinosyltransferase, membrane protein SACE_0178 5 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 134098825 Common - peptidase C60, sortase A and B SACE_2256 14 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 134103286 Common - putative secreted protein SACE_6858 34 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 134097098 Common ectB diaminobutyrate--2-oxoglutarate aminotransferase SACE_0484 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 134099635 Common xdhA xanthine dehydrogenase, molybdopterin binding domain SACE_3093 119 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 134101045 Common hcaC2 3-phenylpropionate dioxygenase ferredoxin subunit SACE_4512 71 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 134101202 Common - amino acid permease-associated region SACE_4670 8 None None None 134097253 Common - cationic amino acid transporter, APC family SACE_0643 191 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 134101010 Common bioF 8-amino-7-oxononanoate synthase SACE_4477 190 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 134096973 Common - pyridoxamine 5'-phosphate oxidase-related,FMN-binding protein SACE_0359 10 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 134099864 Common - phosphatidylethanolamine-binding protein SACE_3325 121 COG1881 COG1881, Phospholipid-binding protein General function prediction only 134100869 Common - amidinotransferase family protein SACE_4336 22 COG1834 COG1834, N-Dimethylarginine dimethylaminohydrolase Amino acid transport and metabolism 134103089 Common - hypothetical protein SACE_6659 19 COG0456 RimI, Acetyltransferases General function prediction only 134098544 Common - hypothetical protein SACE_1970 3 None None None 134097990 Common ssp secreted subtilisin-like protease SACE_1404 120 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 134099676 Common - salicylyl-CoA 5-hydroxylase SACE_3134 179 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 134101917 Nonpathogen - Smr protein/MutS2 SACE_5417 5 None None None 134098277 Common - hypothetical protein SACE_1695 4 None None None 134098583 Common pdx1 pyridoxine biosynthesis protein SACE_2009 87 COG0214 SNZ1, Pyridoxine biosynthesis enzyme Coenzyme metabolism 134102497 Common celA endoglucanase SACE_6060 12 COG5297 CelA, Cellobiohydrolase A (1,4-beta-cellobiosidase A) Carbohydrate transport and metabolism 134103551 Nonpathogen - putative regulator SACE_7129 3 None None None 134100027 Common - response regulator, two-component system SACE_3489 212 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134102303 Common murF UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alani ne ligase SACE_5855 211 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 134102292 Common - hypothetical protein SACE_5844 34 COG3665 COG3665, Uncharacterized conserved protein Function unknown 134100451 Common - glycosyl transferase SACE_3916 219 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 134102424 Common - putative integral membrane transporter SACE_5980 76 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 134097895 Common - siderophore-interacting protein SACE_1308 63 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 134100883 Common - transketolase SACE_4350 220 COG3959 COG3959, Transketolase, N-terminal subunit Carbohydrate transport and metabolism 134101375 Common ygcS putative benzoate transport protein (MFS family) SACE_4846 148 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134100070 Nonpathogen - hypothetical protein SACE_3532 1 None None None 134096818 Common - ABC-type transporter, permease component SACE_0201 76 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 134102638 Common - hypothetical protein SACE_6201 12 COG1846 MarR, Transcriptional regulators Transcription 134097870 Common nrdA ribonucleoside-diphosphate reductase, alpha subunit SACE_1283 222 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 134099529 Common - ABC transporter protein, ATP binding component SACE_2987 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 134099162 Common - hypothetical protein SACE_2613 17 COG5588 COG5588, Uncharacterized conserved protein Function unknown 134101785 Common - hypothetical protein SACE_5282 9 None None None 134100603 Common narJ nitrate reductase delta chain SACE_4068 57 COG2180 NarJ, Nitrate reductase delta subunit Energy production and conversion 134099269 Common - hypothetical protein SACE_2724 23 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 134101714 Common - putative oxidoreductase SACE_5209 167 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 134098852 Common - hypothetical protein SACE_2284 7 None None None 134101217 Common bioF 8-amino-7-oxononanoate synthase SACE_4685 187 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 134096679 Common - NAD-dependent epimerase/dehydratase SACE_0061 55 COG2910 COG2910, Putative NADH-flavin reductase General function prediction only 134097274 Common - hypothetical protein SACE_0665 13 None None None 134101876 Common - putative phosphoesterase SACE_5374 26 COG0622 COG0622, Predicted phosphoesterase General function prediction only 134098920 Common - putative ABC-transporter integral membrane protein SACE_2356 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 134098909 Common - putative hydrolase (partial match) SACE_2345 140 COG2267 PldB, Lysophospholipase Lipid metabolism 134103303 Common - MaoC domain protein dehydratase SACE_6875 62 COG2030 MaoC, Acyl dehydratase Lipid metabolism 134102513 Common frcK putative fructose transport system kinase SACE_6076 39 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 134099248 Common - putative exporter of polyketide antibiotics-like protein SACE_2702 9 COG3559 TnrB3, Putative exporter of polyketide antibiotics Cell envelope biogenesis, outer membrane 134100024 Common - exoenzymes regulatory protein AepA precursor SACE_3486 111 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 134098977 Common - integral membrane protein SACE_2415 6 None None None 134103744 Common - twin-arginine translocation pathway signal SACE_7322 74 COG3211 PhoX, Predicted phosphatase General function prediction only 134103558 Common - glucoamylase SACE_7136 69 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 134103399 Common - multidrug resistance transporter, MFS superfamily SACE_6973 37 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134098775 Common - hypothetical protein SACE_2205 98 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 134102321 Common parA plasmid partitioning protein SACE_5874 188 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 134103175 Common - transcriptional regulator, MarR family SACE_6745 150 COG1733 COG1733, Predicted transcriptional regulators Transcription 134097894 Common - hypothetical protein SACE_1307 9 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 134098239 Common adoK adenosine kinase SACE_1656 123 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 134098446 Common sigT putative RNA polymerase sigma factor SACE_1870 166 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 134101435 Common - transposase SACE_4905 21 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134101376 Common - transcriptional regulator, RpiR family SACE_4847 71 COG1737 RpiR, Transcriptional regulators Transcription 134103718 Common bkdC1 putative dihydrolipoamide acyltransferase component SACE_7296 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 134097580 Nonpathogen - hypothetical protein SACE_0984 1 None None None 134097088 Nonpathogen - hypothetical protein SACE_0474 3 None None None 134100125 Common - hypothetical protein SACE_3587 9 None None None 134096720 Common - two component sensor kinase SACE_0102 214 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 134097303 Common - hypothetical protein SACE_0696 16 None None None 134096757 Common yfiL ABC transporter ATP-binding protein SACE_0139 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 134102826 Common - hypothetical protein SACE_6392 64 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 134102153 Nonpathogen - hypothetical protein SACE_5704 1 None None None 134100860 Common shc1 squalene--hopene cyclase SACE_4327 42 COG1657 SqhC, Squalene cyclase Lipid metabolism 134097488 Common - LysR-family transcriptional regulator SACE_0890 189 COG0583 LysR, Transcriptional regulator Transcription 134099962 Common pyrP uracyl permease SACE_3423 124 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 134100120 Common - hypothetical protein SACE_3582 12 COG3945 COG3945, Uncharacterized conserved protein Function unknown 134101095 Common rhf cytochrome P450 SACE_4562 66 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134102714 Common - secreted protein SACE_6278 14 None None None 134096835 Common - carboxymethylenebutenolidase SACE_0218 69 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 134096994 Nonpathogen - hypothetical protein SACE_0381 1 None None None 134102375 Common - protein of unknown function DUF150 SACE_5928 125 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 134098508 Common - protein of unknown function DUF427 SACE_1933 49 COG2343 COG2343, Uncharacterized protein conserved in bacteria Function unknown 134102358 Common - tetratricopeptide TPR_2 repeat protein SACE_5911 11 None None None 134098734 Common qor putative quinone oxidoreductase SACE_2164 198 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 134098951 Nonpathogen - hypothetical protein SACE_2387 1 None None None 134099662 Common - probable metabolite transporter, MFS superfamily SACE_3120 128 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134103153 Common gcp O-sialoglycoprotein endopeptidase SACE_6723 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 134098127 Common - twin-arginine translocation pathway signal SACE_1541 103 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 134100185 Common - transcription activator, effector binding SACE_3647 18 COG4978 COG4978, Transcriptional regulator, effector-binding domain/component Transcription / Signal transduction mechanisms 134098346 Common - erythromycin esterase SACE_1765 28 COG2312 COG2312, Erythromycin esterase homolog General function prediction only 134103531 Common - hypothetical protein SACE_7108 3 None None None 134097955 Nonpathogen - hypothetical protein SACE_1369 1 None None None 134103146 Common phoD phosphodiesterase/alkaline phosphatase D SACE_6716 57 COG3540 PhoD, Phosphodiesterase/alkaline phosphatase D Inorganic ion transport and metabolism 134101912 Nonpathogen - putative regulator SACE_5411 2 None None None 134103618 Common - protein kinase/transcriptional regulator, LuxR family SACE_7196 51 COG3903 COG3903, Predicted ATPase General function prediction only 134101402 Common - probable aldehyde oxidase and xanthine dehydrogenase family protein transmembrane SACE_4872 119 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 134097707 Common - transcriptional regulator, MarR family SACE_1112 39 COG1846 MarR, Transcriptional regulators Transcription 134103500 Nonpathogen - hypothetical protein SACE_7075 1 None None None 134097081 Nonpathogen - hypothetical protein SACE_0467 5 None None None 134099000 Common hspP2 small heat shock protein SACE_2438 152 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 134102093 Common - putative lipoprotein SACE_5643 36 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 134098614 Common - GCN5-related N-acetyltransferase SACE_2044 7 COG0456 RimI, Acetyltransferases General function prediction only 134100928 Common idnD putative zinc-binding alcohol dehydrogenase SACE_4395 40 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 134098927 Common - putative secreted protein SACE_2363 19 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 134102886 Common - IS21 family transposase SACE_6452 67 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 134101555 Common - ATPase SACE_5031 71 COG2251 COG2251, Predicted nuclease (RecB family) General function prediction only 134100639 Common xylA xylose isomerase SACE_4105 33 COG4952 COG4952, Predicted sugar isomerase Cell envelope biogenesis, outer membrane 134098079 Common - GCN5-related N-acetyltransferase SACE_1493 12 COG0456 RimI, Acetyltransferases General function prediction only 134102653 Common - hypothetical protein SACE_6216 143 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 134103237 Common - adenine dimethylase SACE_6809 27 COG3963 COG3963, Phospholipid N-methyltransferase Lipid metabolism 134099615 Common - hydrogenase expression/formation protein HypD SACE_3073 109 COG0409 HypD, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 134102401 Common cobN cobaltochelatase SACE_5955 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 134099739 Common - hypothetical protein SACE_3200 9 None None None 134099290 Common fadE21 putative acyl-CoA dehydrogenase SACE_2745 153 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134097728 Common - DNA hydrolase with MutT domain SACE_1133 126 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 134097333 Common eryBII TDP-4-keto-6-deoxyhexose 2,3-reductase SACE_0727 201 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 134100844 Common lldD2 L-lactate dehydrogenase SACE_4311 115 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 134100171 Common - probable transposase SACE_3633 24 None None None 134100984 Nonpathogen - hypothetical protein SACE_4451 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 134103540 Common - methyltransferase, UbiE/COQ5 family SACE_7117 151 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134102380 Common - hypothetical protein SACE_5933 91 COG0432 COG0432, Uncharacterized conserved protein Function unknown 134096893 Common - probable kynureninase (kyurenine hydrolase) SACE_0279 56 COG3844 COG3844, Kynureninase Amino acid transport and metabolism 134097805 Common - protein of unknown function DUF81 SACE_1215 114 COG0730 COG0730, Predicted permeases General function prediction only 134097952 Common - MerR-family transcriptional regulator SACE_1366 99 COG0789 SoxR, Predicted transcriptional regulators Transcription 134099029 Common ctpF cation-transporting ATPase SACE_2467 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 134100719 Nonpathogen - hypothetical protein SACE_4186 1 None None None 134103348 Nonpathogen - hypothetical protein SACE_6921 1 None None None 134098328 Common - putative glutamate ABC transporter ATP-binding protein SACE_1746 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 134097692 Common - ABC transporter ATP-binding protein SACE_1096 184 COG0661 AarF, Predicted unusual protein kinase General function prediction only 134099151 Common - flavin-containing monooxygenase FMO SACE_2596 90 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 134102750 Common - putative DeoR-family transcriptional regulator SACE_6315 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 134101017 Common - hypothetical protein, contains GGDEF domain SACE_4484 176 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 134100168 Common - hypothetical protein SACE_3630 12 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 134101317 Nonpathogen - putative glycosyl hydrolase SACE_4785 7 None None None 134100422 Common chiC glycosyl hydrolase, family 18 SACE_3887 20 None None None 134098957 Common - probable membrane sugar transferase SACE_2393 120 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 134097938 Common - formamidopyrimidine-DNA glycosylase SACE_1351 171 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 134103769 Common rpsR 30S ribosomal protein S18 SACE_7349 210 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 134097503 Common hpd3 4-hydroxyphenylpyruvate dioxygenase SACE_0905 77 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 134101586 Nonpathogen - hypothetical protein SACE_5062 1 None None None 134103392 Common - putative two-component system sensor kinase SACE_6966 221 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 134097863 Common - ABC-transport protein, solute-binding component SACE_1274 185 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 134097153 Common - transcriptional regulator, XRE family SACE_0542 49 COG3655 COG3655, Predicted transcriptional regulator Transcription 134099743 Nonpathogen - calcium binding protein SACE_3204 2 COG5126 FRQ1, Ca2+-binding protein (EF-Hand superfamily) Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only 134100546 Common catF acetyl-CoA acetyltransferase SACE_4011 180 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 134103589 Nonpathogen - hypothetical protein SACE_7167 1 None None None 134097948 Common clpX ATP-dependent protease ATP-binding subunit SACE_1362 219 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 134100615 Common - probable transcriptional regulator, MarR family SACE_4080 59 COG1846 MarR, Transcriptional regulators Transcription 134102199 Common trpC indole-3-glycerol-phosphate synthase SACE_5750 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 134097902 Common - hypothetical protein SACE_1315 2 None None None 134103542 Nonpathogen - hypothetical protein SACE_7119 1 None None None 134099912 Common - hypothetical protein SACE_3373 3 None None None 134102487 Common trmD tRNA (guanine-N(1)-)-methyltransferase SACE_6050 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 134097780 Common - cobalt transport system permease protein SACE_1190 25 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 134098879 Common - IS1647-like transposase SACE_2314 39 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134103771 Common rpsF 30S ribosomal protein S6 SACE_7351 185 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 134100824 Common cdaR transcriptional regulator SACE_4291 22 COG3629 DnrI, DNA-binding transcriptional activator of the SARP family Signal transduction mechanisms 134097173 Common - hypothetical protein SACE_0562 4 None None None 134103461 Nonpathogen - hypothetical protein SACE_7036 1 None None None 134101281 Nonpathogen - hypothetical protein SACE_4749 1 None None None 134097135 Common - hypothetical protein SACE_0524 65 COG2013 COG2013, Uncharacterized conserved protein Function unknown 134097826 Common pacB3 penicillin acylase SACE_1237 41 COG2366 COG2366, Protein related to penicillin acylase General function prediction only 134101939 Common - gamma-aminobutyrate permease SACE_5440 115 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 134103504 Common - secreted trypsin-like serine protease SACE_7079 31 COG5640 COG5640, Secreted trypsin-like serine protease Posttranslational modification, protein turnover, chaperones 134099161 Common - hypothetical protein SACE_2612 14 COG5486 COG5486, Predicted metal-binding integral membrane protein Function unknown 134096684 Nonpathogen - hypothetical protein SACE_0066 1 COG3207 DIT1, Pyoverdine/dityrosine biosynthesis protein Secondary metabolites biosynthesis, transport, and catabolism 134103141 Common sigD RNA polymerase sigma factor SACE_6711 88 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 134100083 Common paaB putative phenylacetic acid degradation protein SACE_3545 38 COG3460 COG3460, Uncharacterized enzyme of phenylacetate metabolism Secondary metabolites biosynthesis, transport, and catabolism 134096634 Common - transcriptional regulator, LuxR family SACE_0016 32 COG3899 COG3899, Predicted ATPase General function prediction only 134102170 Nonpathogen - hypothetical protein SACE_5721 2 None None None 134103796 Common - hypothetical protein SACE_7376 124 COG1678 COG1678, Putative transcriptional regulator Transcription 134098539 Common - putative DNA binding protein SACE_1965 123 COG1278 CspC, Cold shock proteins Transcription 134098001 Common rpmA 50S ribosomal protein L27 SACE_1415 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 134098132 Common - transcriptional regulator, XRE family SACE_1546 6 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 134100751 Common - putative permease of the drug/metabolite transporter (DMT) superfamily SACE_4218 4 COG2510 COG2510, Predicted membrane protein Function unknown 134097417 Common - transcriptional regulator, HxlR family SACE_0812 145 COG1733 COG1733, Predicted transcriptional regulators Transcription 134102147 Nonpathogen - hypothetical protein SACE_5698 1 None None None 134103414 Common - hypothetical protein SACE_6988 11 None None None 134098529 Common cvnB11 hypothetical protein SACE_1954 15 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 134099822 Nonpathogen - hypothetical protein SACE_3283 1 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 134100351 Nonpathogen - major facilitator superfamily MFS_1 SACE_3816 6 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 134097387 Common - NADPH-dependent FMN reductase SACE_0781 113 COG0431 COG0431, Predicted flavoprotein General function prediction only 134100438 Common - glycoside hydrolase family 2, sugar binding SACE_3903 66 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 134102522 Common kdpE two-component response regulator SACE_6085 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 134102788 Common - hypothetical protein SACE_6354 5 COG4578 GutM, Glucitol operon activator Transcription 134099800 Common - hypothetical protein SACE_3261 7 None None None 134103058 Nonpathogen - hypothetical protein SACE_6628 1 None None None 134101888 Nonpathogen - probable branched chain amino acid transport protein SACE_5386 4 COG1687 AzlD, Predicted branched-chain amino acid permeases (azaleucine resistance) Amino acid transport and metabolism 134099728 Nonpathogen - hypothetical protein SACE_3188 1 None None None 134100610 Nonpathogen - hypothetical protein SACE_4075 7 None None None 134102389 Common - ATP-dependent RNA helicase SACE_5942 233 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 134103699 Common - ABC transporter, permease protein SACE_7277 146 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 134098597 Common ruvB Holliday junction DNA helicase B SACE_2023 226 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 134097057 Common - tRNA/rRNA methyltransferase SACE_0444 214 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 134103409 Common - putative transcriptional regulator SACE_6983 64 COG2378 COG2378, Predicted transcriptional regulator Transcription 134103099 Common sucC succinyl-CoA synthetase subunit beta SACE_6669 207 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 134101060 Common - hypothetical protein SACE_4527 24 COG3535 COG3535, Uncharacterized conserved protein Function unknown 134103512 Common - diguanylate cyclase SACE_7088 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 134098981 Nonpathogen - hypothetical protein SACE_2419 1 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 134097965 Nonpathogen - hypothetical protein SACE_1379 2 None None None 134098474 Common - putative HTH-type transcriptional regulator SACE_1899 7 None None None 134098940 Common adk adenylate kinase SACE_2376 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 134099210 Common - peptidase M50 SACE_2663 42 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 134099816 Common - xylose isomerase-like TIM barrel SACE_3277 65 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 134097621 Common - transcriptional regulator, PadR-like family SACE_1025 68 COG1695 COG1695, Predicted transcriptional regulators Transcription 134102573 Common - cystathionine gamma-lyase SACE_6136 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 134103706 Common - glutamine ABC transporter, ATP-binding protein SACE_7284 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 134097452 Common - oligopeptide ABC transporter ATP-binding protein SACE_0847 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 134097798 Common - rhomboid-like protein SACE_1208 29 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 134100397 Common - amino acid permease-associated region SACE_3862 141 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 134097363 Nonpathogen rpmF 50S ribosomal protein L32 SACE_0757 1 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 134099657 Common yqhE 2,5-diketo-D-gluconic acid reductase A SACE_3115 112 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 134101209 Common - transcriptional regulator, IclR family SACE_4677 113 COG1414 IclR, Transcriptional regulator Transcription 134102141 Common - hypothetical protein SACE_5692 93 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 134100627 Common gudB NAD-specific glutamate dehydrogenase SACE_4093 76 COG2902 COG2902, NAD-specific glutamate dehydrogenase Amino acid transport and metabolism 134102989 Common - chitinase II SACE_6557 38 COG3325 ChiA, Chitinase Carbohydrate transport and metabolism 134099231 Common - putative metal-dependent amidase/aminoacylase/carboxypeptidase SACE_2685 166 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 134101140 Common opuD glycine betaine transporter SACE_4607 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 134098761 Common - possible transcriptional regulator, TetR family SACE_2191 10 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 134096656 Common srtB putative sortase-like protein SACE_0038 21 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 134101198 Common - hypothetical protein SACE_4666 3 None None None 134099419 Common gdmM putative 3-(3-hydroxylphenyl)-propionate hydroxylase SACE_2877 116 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 134098899 Common - transposase SACE_2335 56 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134097168 Common - sensor signal transduction histidine kinase SACE_0557 10 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 134100892 Common - probable CoA-transferase SACE_4359 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 134102230 Common - oxygenase SACE_5782 11 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 134103488 Common - two component system response regulator SACE_7063 212 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134103442 Nonpathogen - hypothetical protein SACE_7017 1 None None None 134099510 Common - putative 3-oxoacyl-ACP synthase SACE_2968 203 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134100620 Common adh alcohol dehydrogenase SACE_4085 195 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 134098265 Common - putative two-component system response regulator SACE_1682 11 None None None 134099336 Common - peptidase S9, prolyl oligopeptidase SACE_2791 100 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 134100015 Common - putative transcriptional regulator SACE_3477 56 COG1309 AcrR, Transcriptional regulator Transcription 134100157 Common - possible tyrosine recombinase SACE_3619 3 None None None 134098992 Common - rhodanese-like protein SACE_2430 44 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 134097402 Common - putative ABC transporter, integral membrane subunit SACE_0796 46 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 134101863 Common - two component system histidine kinase SACE_5361 73 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 134102319 Common - hypothetical protein SACE_5872 11 None None None 134102670 Nonpathogen - hypothetical protein SACE_6233 1 None None None 134098426 Common - hypothetical protein SACE_1850 9 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 134100057 Common adh probable alcohol dehydrogenase (Zn-dependent) SACE_3519 204 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 134102098 Common - putative transposase SACE_5648 51 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 134102476 Common rpsB 30S ribosomal protein S2 SACE_6038 219 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 134100465 Common - transcriptional regulator, LuxR family SACE_3930 10 COG3899 COG3899, Predicted ATPase General function prediction only 134098695 Common - possible membrane protein SACE_2125 7 None None None 134100331 Common mob putative molybdopterin-guanine dinucleotide biosynthesis protein SACE_3796 10 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 134100218 Nonpathogen - hypothetical protein SACE_3680 3 None None None 134097812 Common - membrane-flanked domain protein SACE_1222 12 COG3402 COG3402, Uncharacterized conserved protein Function unknown 134096689 Nonpathogen - hypothetical protein SACE_0071 1 None None None 134100781 Common - hypothetical protein SACE_4248 9 COG5516 COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding General function prediction only 134098611 Nonpathogen - hypothetical protein SACE_2039 2 None None None 134099407 Common aroD 3-dehydroquinate dehydratase SACE_2865 169 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 134100327 Common - ribosomal RNA adenine dimethylase domain protein SACE_3792 25 COG3963 COG3963, Phospholipid N-methyltransferase Lipid metabolism 134102083 Common - putative sodium:solute symporter SACE_5633 157 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 134101471 Common kdgR transcriptional regulator (IclR family) SACE_4941 98 COG1414 IclR, Transcriptional regulator Transcription 134102923 Common - sensor kinase, two-component system SACE_6490 58 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 134100767 Common - phospholipase D/transphosphatidylase SACE_4234 62 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 134097846 Common - hypothetical protein SACE_1257 37 COG2068 COG2068, Uncharacterized MobA-related protein General function prediction only 134101829 Nonpathogen - hypothetical protein SACE_5326 1 None None None 134097658 Common - hypothetical protein SACE_1062 13 None None None 134101399 Nonpathogen - hypothetical protein SACE_4869 1 None None None 134100208 Common - transcriptional regulator, XRE family SACE_3670 41 COG1396 HipB, Predicted transcriptional regulators Transcription 134102616 Common - hypothetical protein SACE_6179 3 None None None 134097791 Common - ATP-dependent Clp protease adaptor protein ClpS SACE_1201 16 COG2127 COG2127, Uncharacterized conserved protein Function unknown 134103172 Common - transcriptional regulator, XRE family SACE_6742 6 COG1396 HipB, Predicted transcriptional regulators Transcription 134097027 Common clpC putative ATP-dependent Clp protease SACE_0414 223 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 134099998 Common pdxA 4-hydroxythreonine-4-phosphate dehydrogenase SACE_3460 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 134099046 Common - peptidase S1 and S6, chymotrypsin/Hap SACE_2489 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 134098585 Common - probable transcriptional regulator SACE_2011 60 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 134102660 Common - hypothetical protein SACE_6223 6 None None None 134101075 Common - transcriptional regulator, BadM/Rrf2 family SACE_4542 136 COG1959 COG1959, Predicted transcriptional regulator Transcription 134098690 Common rpe ribulose-phosphate 3-epimerase SACE_2120 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 134097590 Nonpathogen - putative ABC transporter integral membrane protein SACE_0994 10 COG4200 COG4200, Uncharacterized protein conserved in bacteria Function unknown 134098184 Common rnr ribonuclease R SACE_1600 189 COG0557 VacB, Exoribonuclease R Transcription 134097497 Common cysM2 cystathionine beta-synthase SACE_0899 220 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 134102631 Nonpathogen - hypothetical protein SACE_6194 1 None None None 134101097 Common avtA valine--pyruvate transaminase SACE_4564 187 COG3977 COG3977, Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase Amino acid transport and metabolism 134101279 Nonpathogen - hypothetical protein SACE_4747 8 None None None 134097124 Nonpathogen - hypothetical protein SACE_0513 3 None None None 134103447 Common - hypothetical protein SACE_7022 4 None None None 134099347 Common - putative cytochrome P450 hydroxylase SACE_2802 73 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134101752 Common recN recombination and DNA repair protein SACE_5248 197 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 134100652 Common - general substrate transporters SACE_4118 47 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134100672 Common - type I modular polyketide synthase SACE_4139 221 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134101447 Common - IS630 family transposase SACE_4917 12 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 134101451 Common pltG probable thioesterase SACE_4921 37 COG3208 GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 134101485 Common - transposase SACE_4955 12 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 134099085 Common - IS1647-like transposase SACE_2529 27 None None None 134099329 Common - flavin reductase-like, FMN-binding SACE_2784 104 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 134096661 Common - hypothetical protein SACE_0043 4 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 134100491 Common - nucleotidyltransferase SACE_3956 5 None None None 134100908 Common - putative ABC transporter solute-binding protein SACE_4375 72 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 134097392 Common - probable transcriptional regulator, TetR family SACE_0786 67 COG1309 AcrR, Transcriptional regulator Transcription 134100913 Common - transcriptional regulator, LysR family SACE_4380 188 COG0583 LysR, Transcriptional regulator Transcription 134096736 Common - hypothetical protein SACE_0118 6 None None None 134097613 Nonpathogen - hypothetical protein SACE_1017 1 None None None 134098678 Common priA primosomal protein N' (replication factor Y) SACE_2108 137 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 134103337 Common - hypothetical protein SACE_6910 5 None None None 134096908 Nonpathogen - PE-PGRS family protein SACE_0294 1 None None None 134097284 Common - probable copper resistance transporter SACE_0677 13 COG1276 PcoD, Putative copper export protein Inorganic ion transport and metabolism 134098145 Nonpathogen - hypothetical protein SACE_1559 1 None None None 134101737 Common plsC 1-acylglycerol-3-phosphate O-acyltransferase SACE_5233 82 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 134098629 Common - PTS system, N-acetylglucosamine-specific IIBC subunit SACE_2059 49 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 134097160 Common - hypothetical protein SACE_0549 3 None None None 134101440 Common nirB nitrite reductase (NAD(P)H) large subunit SACE_4910 192 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 134102950 Common glpF glycerol uptake facilitator protein SACE_6517 130 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 134097349 Common - putative methyltransferase,S-adenosyl-L-methionine (SAM)-MTase protein SACE_0743 94 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134102286 Common - DeoR-family transcriptional regulator SACE_5838 38 COG2378 COG2378, Predicted transcriptional regulator Transcription 134097536 Common - hypothetical protein SACE_0938 5 None None None 134099174 Common - 5-carboxymethyl-2-hydroxymuconate delta-isomerase SACE_2626 176 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 134100232 Common - lysine exporter protein (LysE/YggA) SACE_3694 106 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 134101634 Nonpathogen - hypothetical protein SACE_5122 8 None None None 134102208 Common hisA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase SACE_5759 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 134099190 Nonpathogen - hypothetical protein SACE_2643 1 None None None 134101677 Common - L-asparagine operon repressor SACE_5169 136 COG2186 FadR, Transcriptional regulators Transcription 134100221 Common - probable chloramphenicol O-acetyltransferase SACE_3683 70 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 134102051 Common - oxygenase SACE_5601 106 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 134096866 Common - putative DNA polymerase III gamma subunit SACE_0251 245 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 134098322 Common edd phosphogluconate dehydratase SACE_1740 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 134098552 Common - proline dehydrogenase SACE_1978 121 COG0506 PutA, Proline dehydrogenase Amino acid transport and metabolism 134099453 Common - voltage-gated sodium channel SACE_2911 26 None None None 134097633 Common - putative ECF family RNA polymerase sigma factor SACE_1037 169 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 134099499 Nonpathogen - hypothetical protein SACE_2957 1 None None None 134103729 Common - activator of HSP90 ATPase-like SACE_7307 63 COG3832 COG3832, Uncharacterized conserved protein Function unknown 134098463 Common bcpB bacterioferritin comigratory protein SACE_1887 206 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 134097207 Common - glutamine cyclotransferase precursor SACE_0597 22 COG3823 COG3823, Glutamine cyclotransferase Posttranslational modification, protein turnover, chaperones 134097376 Common - hypothetical protein SACE_0770 22 COG3745 CpaB, Flp pilus assembly protein CpaB Intracellular trafficking and secretion 134097700 Common - possible transcriptional regulator, PadR family SACE_1104 19 COG1695 COG1695, Predicted transcriptional regulators Transcription 134102266 Common pntAA NAD(P) transhydrogenase subunit alpha SACE_5818 166 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 134098704 Common - amino acid ABC transporter, permease protein,putative SACE_2134 64 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 134097194 Nonpathogen - hypothetical protein SACE_0584 2 None None None 134102351 Common - hypothetical protein SACE_5904 23 None None None 134100036 Common - ABC-type multidrug transport system ATPase and permease components SACE_3498 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 134100043 Common - protein of unknown function DUF162 SACE_3505 21 COG1556 COG1556, Uncharacterized conserved protein Function unknown 134098158 Common - hypothetical protein SACE_1572 10 None None None 134100965 Common - aliphatic sulfonates-binding lipoprotein SACE_4432 98 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 134099461 Common - putative secreted protein (partial match) SACE_2919 6 None None None 134097069 Common speE spermidine synthase SACE_0456 113 COG4262 COG4262, Predicted spermidine synthase with an N-terminal membrane domain General function prediction only 134101746 Common xerD integrase/recombinase SACE_5242 228 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 134101465 Common kdgK 2-keto-3-deoxygluconate kinase SACE_4935 90 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 134103661 Common - camphor resistance CrcB protein SACE_7239 51 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 134098453 Nonpathogen - hypothetical protein SACE_1877 1 None None None 134102723 Nonpathogen - hypothetical protein SACE_6287 2 None None None 134098635 Common aroF chorismate synthase SACE_2065 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 134101082 Common - 4-hydroxythreonine-4-phosphate dehydrogenase SACE_4549 19 COG3395 COG3395, Uncharacterized protein conserved in bacteria Function unknown 134102687 Nonpathogen - hypothetical protein SACE_6250 1 None None None 134098988 Common - hypothetical protein SACE_2426 5 None None None 134097914 Common - hypothetical protein SACE_1327 7 None None None 134100916 Common catC muconolactone delta-isomerase (MIase) SACE_4383 24 COG4829 CatC1, Muconolactone delta-isomerase Secondary metabolites biosynthesis, transport, and catabolism 134099205 Common - cold-shock DNA-binding domain protein SACE_2658 180 COG1278 CspC, Cold shock proteins Transcription 134096926 Common - GatB/YqeY SACE_0312 144 COG1610 COG1610, Uncharacterized conserved protein Function unknown 134100336 Common nirB assimilatory nitrite reductase large subunit SACE_3801 231 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 134101928 Common coaE dephospho-CoA kinase/unknown domain fusion protein SACE_5429 207 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 134097444 Common - septum formation initiator SACE_0839 9 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 134102347 Common - hypothetical protein SACE_5900 15 None None None 134101290 Common - short-chain dehydrogenase/reductase SDR SACE_4758 221 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134100386 Common hexA beta-N-acetylhexosaminidase SACE_3851 54 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 134098173 Common - putative sugar transport system permease protein SACE_1587 133 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 134103319 Common nuoL NADH dehydrogenase subunit L SACE_6891 209 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 134099410 Common shnQ 3-dehydroquinate synthase SACE_2868 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 134098106 Nonpathogen - hypothetical protein SACE_1520 1 None None None 134101089 Common - HpcH/HpaI aldolase SACE_4556 74 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 134100551 Common - carbon monoxide dehydrogenase subunit G SACE_4016 42 COG3427 COG3427, Uncharacterized conserved protein Function unknown 134103429 Nonpathogen - hypothetical protein SACE_7003 1 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 134099217 Common - transport system permease protein SACE_2670 77 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 134101458 Common - flavin reductase-like, FMN-binding SACE_4928 117 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 134103291 Common mce5A putative Mce family protein SACE_6863 8 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 134102772 Common - hypothetical protein SACE_6338 7 None None None 134103762 Common - transcriptional regulator, XRE family with cupin sensor SACE_7342 99 COG1396 HipB, Predicted transcriptional regulators Transcription 134103163 Common - DNA-binding protein SACE_6733 10 COG2964 COG2964, Uncharacterized protein conserved in bacteria Function unknown 134098566 Common - cyclopropane-fatty-acyl-phospholipid synthase SACE_1992 134 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 134097424 Common - stearoyl-CoA 9-desaturase SACE_0819 70 COG1398 OLE1, Fatty-acid desaturase Lipid metabolism 134101478 Common - TetR-family transcriptional regulator SACE_4948 85 COG1309 AcrR, Transcriptional regulator Transcription 134101265 Common - sugar transporter, MFS superfamily SACE_4733 169 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134098718 Common - amidohydrolase family protein SACE_2148 42 COG3618 COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 134103400 Common - transcriptional regulator, ArsR family SACE_6974 38 COG0640 ArsR, Predicted transcriptional regulators Transcription 134099526 Common - ROK-family transcriptional regulator SACE_2984 143 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 134098360 Common - possible acetyl-CoA synthetase SACE_1780 174 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 134099321 Common - transcriptional regulator, IclR family SACE_2776 120 COG1414 IclR, Transcriptional regulator Transcription 134099363 Nonpathogen - hypothetical protein SACE_2820 3 None None None 134098191 Common - transcriptional regulator, MarR family SACE_1607 21 COG1846 MarR, Transcriptional regulators Transcription 134099795 Common iolE sugar phosphate isomerase/epimerase SACE_3256 39 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 134100570 Common pobA 4-hydroxybenzoate 3-monooxygenase SACE_4035 52 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 134103753 Common - hypothetical protein SACE_7333 51 COG1309 AcrR, Transcriptional regulator Transcription 134100704 Common - putative glutamate--cysteine ligase SACE_4171 60 COG2170 COG2170, Uncharacterized conserved protein Function unknown 134101112 Common - putative membrane transport protein SACE_4579 36 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 134102736 Common argS arginyl-tRNA synthetase SACE_6300 245 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 134100515 Common - TetR-family transcriptional regulator SACE_3980 19 COG1309 AcrR, Transcriptional regulator Transcription 134100222 Common - putative antibiotic ABC transporter protein,ATP-binding SACE_3684 245 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 134101696 Common - hypothetical protein SACE_5188 13 None None None 134101820 Common - hypothetical protein SACE_5317 2 COG4460 COG4460, Uncharacterized protein conserved in bacteria Function unknown 134099752 Common - DegT/DnrJ/EryC1/StrS aminotransferase SACE_3213 194 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 134097246 Common ureC urease subunit alpha SACE_0636 96 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 134101167 Common livG branched-chain amino acid ABC transporter ATP-binding protein SACE_4634 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 134103298 Common rplA 50S ribosomal protein L1 SACE_6870 229 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 134102278 Common - cell division initiation protein SACE_5830 21 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 134103197 Common glmS D-fructose-6-phosphate amidotransferase SACE_6768 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 134098301 Common - possible lipoprotein SACE_1719 4 None None None 134102250 Common nadB L-aspartate oxidase SACE_5802 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 134098162 Common - transcriptional regulator, TetR family SACE_1576 74 COG1309 AcrR, Transcriptional regulator Transcription 134099441 Common fscRIV LuxR-family transcriptional regulator SACE_2899 25 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 134100390 Common dhbA,entA 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase SACE_3855 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134097339 Common ermE N-6-aminoadenine-N-methyltransferase,erythromycin resistance SACE_0733 241 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 134101446 Common - protein of unknown function DUF711 SACE_4916 48 COG2848 COG2848, Uncharacterized conserved protein Function unknown 134101486 Common - IS3 family transposase SACE_4956 78 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 134099226 Common - secreted protein SACE_2680 20 COG4632 EpsL, Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Carbohydrate transport and metabolism 134102060 Common - putative transcriptional regulator SACE_5610 55 COG0789 SoxR, Predicted transcriptional regulators Transcription 134097055 Common - HAD-superfamily hydrolase subfamily IA, variant 3 SACE_0442 25 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 134102694 Common - RNA polymerase sigma factor SACE_6258 42 COG4941 COG4941, Predicted RNA polymerase sigma factor containing a TPR repeat domain Transcription 134097367 Common - putative two-component system response regulator SACE_0761 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 134098460 Common - antibiotic resistance macrolide glycosyltransferase SACE_1884 42 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 134103591 Common glpQ glycerophosphoryl diester phosphodiesterase SACE_7169 115 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 134099225 Common - transcriptional regulator, TetR family SACE_2679 43 COG1309 AcrR, Transcriptional regulator Transcription 134100743 Common - glucose-methanol-choline oxidoreductase SACE_4210 85 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 134097362 Common rpmE2 50S ribosomal protein L31 type B SACE_0756 167 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 134102148 Common - acyl-CoA dehydrogenase SACE_5699 162 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134097305 Common - oxidoreductase SACE_0698 17 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 134098105 Nonpathogen - hypothetical protein SACE_1519 1 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 134098563 Common cya adenylate cyclase SACE_1989 27 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 134097882 Nonpathogen - hypothetical protein SACE_1295 1 None None None 134099753 Nonpathogen - hypothetical protein SACE_3214 2 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 134098300 Common - DeoR-family transcriptional regulator SACE_1718 63 COG2378 COG2378, Predicted transcriptional regulator Transcription 134098719 Common menG ribonuclease activity regulator protein RraA SACE_2149 77 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 134097029 Common ORFL4 transposase, ISlxx1-degenerated SACE_0416 54 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 134100820 Common - putative non-ribosomal peptide synthetase SACE_4287 219 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134101922 Common - hypothetical protein SACE_5423 6 COG2306 COG2306, Uncharacterized conserved protein Function unknown 134100207 Common - putative two-component system response regulator SACE_3669 208 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134100621 Nonpathogen - hypothetical protein SACE_4086 2 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 134099342 Nonpathogen - hypothetical protein SACE_2797 1 None None None 134101188 Nonpathogen - hypothetical protein SACE_4655 1 None None None 134102344 Common - hypothetical protein SACE_5897 2 None None None 134098699 Common - solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta SACE_2129 40 COG3382 COG3382, Uncharacterized conserved protein Function unknown 134100550 Common echA6 enoyl-CoA hydratase SACE_4015 26 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 134103763 Common - possible enhanced intracellular survival protein SACE_7343 13 COG4552 Eis, Predicted acetyltransferase involved in intracellular survival and related acetyltransferases General function prediction only 134103749 Common - multidrug resistance efflux transporter SACE_7328 217 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134101936 Common polA DNA polymerase I SACE_5437 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 134098168 Common - NGG1-interacting factor 3 SACE_1582 131 COG0327 COG0327, Uncharacterized conserved protein Function unknown 134097378 Nonpathogen - hypothetical protein SACE_0772 1 None None None 134097858 Common - aldo/keto reductase SACE_1269 204 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 134102977 Common - NADH dehydrogenase (quinone) SACE_6545 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 134100763 Common - serine/threonine protein kinase SACE_4230 10 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 134102277 Nonpathogen - hypothetical protein SACE_5829 2 None None None 134100223 Nonpathogen - hypothetical protein SACE_3685 1 None None None 134097136 Common - cold-shock DNA-binding domain protein SACE_0525 178 COG1278 CspC, Cold shock proteins Transcription 134102640 Common hrpA ATP-dependent helicase SACE_6203 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 134103655 Nonpathogen - hypothetical protein SACE_7233 1 None None None 134099082 Common ureC urease subunit alpha SACE_2526 96 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 134103727 Nonpathogen - hypothetical protein SACE_7305 1 COG2968 COG2968, Uncharacterized conserved protein Function unknown 134103424 Common - RNA polymerase sigma factor SACE_6998 17 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 134101410 Common - ABC transporter ATP-binding protein SACE_4880 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 134097388 Common - multi-domain regulatory protein SACE_0782 38 COG3903 COG3903, Predicted ATPase General function prediction only 134099993 Common - putative pyridine nucleotide-disulphide oxidoreductase SACE_3455 237 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 134102840 Common hutU urocanate hydratase SACE_6406 97 COG2987 HutU, Urocanate hydratase Amino acid transport and metabolism 134101455 Common - long-chain acyl-CoA synthetase, putative SACE_4925 140 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 134098694 Common ribH riboflavin synthase beta chain SACE_2124 210 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 134100332 Common - cell wall-associated hydrolase SACE_3797 90 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 134098620 Common - secreted protein SACE_2050 11 COG4768 COG4768, Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain General function prediction only 134099365 Common vanK vanillate transporter (MFS superfamily) SACE_2822 50 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134102374 Common nusA transcription elongation factor NusA SACE_5927 229 COG0195 NusA, Transcription elongation factor Transcription 134101487 Nonpathogen - lantibiotic dehydratase-like SACE_4957 6 None None None 134099371 Common - Transposase SACE_2828 45 None None None 134101751 Common - hypothetical protein SACE_5247 19 COG4825 COG4825, Uncharacterized membrane-anchored protein conserved in bacteria Function unknown 134101664 Common - binding-protein-dependent transport permease SACE_5156 154 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 134101273 Common - hypothetical protein SACE_4741 14 None None None 134097752 Common - carbon monoxide dehydrogenase, medium chain SACE_1160 89 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 134101543 Common - hypothetical protein SACE_5016 23 COG3858 COG3858, Predicted glycosyl hydrolase General function prediction only 134102447 Nonpathogen - hypothetical protein SACE_6003 1 None None None 134098369 Common - hypothetical protein SACE_1789 2 None None None 134096640 Common - putative multi-domain beta-ketoacyl synthase SACE_0022 58 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134097314 Common - hypothetical protein SACE_0707 3 COG3339 COG3339, Uncharacterized conserved protein Function unknown 134103246 Common rpmD 50S ribosomal protein L30 SACE_6818 100 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 134103264 Common rplC 50S ribosomal protein L3 SACE_6836 241 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 134097332 Common eryCIII glycosyl transferase, NDP-D-desosamine : 3-L-mycarosyl erythronolide B SACE_0726 51 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 134101665 Common - solute binding protein of ABC transporter system SACE_5157 51 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 134098984 Common - hypothetical protein SACE_2422 3 None None None 134099360 Nonpathogen - hypothetical protein SACE_2817 1 None None None 134100306 Common - hypothetical protein SACE_3771 5 None None None 134098632 Common - PTS system, glucose-specific component SACE_2062 60 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 134099448 Nonpathogen - Putative Lactoylglutathione lyase SACE_2906 3 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 134103742 Common - hypothetical protein SACE_7320 34 COG2720 COG2720, Uncharacterized vancomycin resistance protein Defense mechanisms 134100226 Nonpathogen - hypothetical protein SACE_3688 1 COG0456 RimI, Acetyltransferases General function prediction only 134102133 Common - DsbA-like thioredoxin domain protein SACE_5683 73 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 134100904 Nonpathogen - hypothetical protein SACE_4371 1 None None None 134102263 Common dnaE DNA polymerase III subunit alpha SACE_5815 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 134103712 Common nosF ATP/GTP binding protein NosF' SACE_7290 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 134100316 Common - SPFH domain/band 7 family protein SACE_3781 218 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 134096867 Nonpathogen - hypothetical protein SACE_0252 1 None None None 134102288 Common - putative suagr ABC transporter permease protein SACE_5840 142 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 134099159 Common - IS21 family transposase SACE_2605 70 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 134103451 Nonpathogen - hypothetical protein SACE_7026 1 None None None 134097840 Common - putative aldo/keto reductase SACE_1251 195 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 134101083 Common - extracellular solute-binding protein SACE_4550 186 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 134100003 Common ilvB1 acetolactate synthase SACE_3465 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 134098550 Common - putative two-component system sensor kinase SACE_1976 146 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 134101110 Nonpathogen - hypothetical protein SACE_4577 1 None None None 134102777 Nonpathogen - hypothetical protein SACE_6343 1 None None None 134097634 Common - O-methyltransferase, family 3 SACE_1038 21 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 134103454 Nonpathogen - hypothetical protein SACE_7029 1 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 134100040 Nonpathogen - hypothetical protein SACE_3502 1 None None None 134100572 Common - acyl-CoA synthase SACE_4037 221 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134098372 Common - hypothetical protein SACE_1792 8 None None None 134102203 Common - transcriptional regulator, TetR family SACE_5754 37 COG1309 AcrR, Transcriptional regulator Transcription 134096842 Common - putative 3-oxoacyl-(acyl carrier protein) reductase SACE_0225 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134099872 Nonpathogen - hypothetical protein SACE_3333 1 None None None 134103665 Common - FAD-dependent oxygenase SACE_7243 39 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 134098365 Common - protein tyrosine/serine phosphatase SACE_1785 47 COG2365 COG2365, Protein tyrosine/serine phosphatase Signal transduction mechanisms 134097373 Nonpathogen - hypothetical protein SACE_0767 2 None None None 134098600 Common - preprotein translocase subunit SecF SACE_2026 201 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 134097159 Nonpathogen - hypothetical protein SACE_0548 1 None None None 134101119 Common - probable hydrolase SACE_4586 176 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134097573 Common bioF 8-amino-7-oxononanoate synthase SACE_0977 188 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 134101898 Common - hypothetical protein SACE_5396 6 None None None 134102391 Common cobL precorrin-6Y C(5,15)-methyltransferase (decarboxylating) SACE_5944 104 COG2241 CobL, Precorrin-6B methylase 1 Coenzyme metabolism 134100946 Common - ABC sulfonate transporter, substrate binding component SACE_4413 30 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 134100324 Common gnl gluconolactonase, putative SACE_3789 72 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 134103810 Common parB chromosome partitioning SACE_7390 183 COG1475 Spo0J, Predicted transcriptional regulators Transcription 134101480 Common - short-chain dehydrogenase/reductase SDR SACE_4950 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134098403 Common - acetyl-coa acetyltransferase (thiolase) SACE_1824 175 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 134102237 Common - dipeptide/oligopeptide ABC transporter, permease protein SACE_5789 216 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 134099455 Common - transcriptional regulator SACE_2913 57 COG1316 LytR, Transcriptional regulator Transcription 134097585 Common estC carboxylesterase SACE_0989 66 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 134103092 Common - hypothetical protein SACE_6662 7 None None None 134101070 Common iolG myo-inositol 2-dehydrogenase SACE_4537 134 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 134099808 Common crtB putative phytoene synthase SACE_3269 105 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 134097202 Common - haloacid dehalogenase-like hydrolase SACE_0592 7 COG0546 Gph, Predicted phosphatases General function prediction only 134101561 Common - transposase SACE_5037 53 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134100039 Common pat acetyltransferase SACE_3501 13 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 134102731 Common rho1 transcription termination factor Rho SACE_6295 199 COG1158 Rho, Transcription termination factor Transcription 134096652 Common - putative peptidyl-prolyl cis-trans isomerase SACE_0034 187 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 134100254 Common - D-beta-hydroxybutyrate dehydrogenase SACE_3718 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134098249 Common - sugar ABC transporter substrate-binding protein SACE_1666 123 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 134099982 Common - AMP-dependent synthetase and ligase SACE_3444 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134097778 Common serB phosphoserine phosphatase SACE_1188 164 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 134101199 Common - ferric uptake regulation protein SACE_4667 100 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 134097477 Common - hypothetical protein SACE_0877 29 COG5483 COG5483, Uncharacterized conserved protein Function unknown 134098615 Nonpathogen - hypothetical protein SACE_2045 1 None None None 134097161 Nonpathogen - hypothetical protein SACE_0550 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 134097466 Common - transcriptional regulator, XRE family SACE_0864 6 None None None 134100782 Nonpathogen - hypothetical protein SACE_4249 4 None None None 134100236 Common - modification methylase, HemK family SACE_3698 207 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 134100968 Common - Crp-family transcriptional regulator SACE_4435 118 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 134098339 Common - IS1533 transposase SACE_1757 6 None None None 134099450 Common - dehydrogenase, putative myo-inositol 2-dehydrogenase SACE_2908 159 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 134098471 Common - protein of unknown function DUF397 SACE_1896 6 None None None 134101416 Common - cytochrome P450 monooxygenase SACE_4886 9 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134103149 Nonpathogen - hypothetical protein SACE_6719 1 None None None 134096923 Common - peptide hydrolase SACE_0309 141 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 134098189 Common pheC cyclohexadienyl dehydratase SACE_1605 123 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 134101278 Common - hypothetical protein SACE_4746 12 None None None 134101675 Common - transcriptional regulator, AraC family SACE_5167 108 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 134098210 Common - oxidoreductase, short-chain dehydrogenase/reductase family SACE_1627 201 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134099536 Common - glycosyl hydrolase SACE_2994 7 None None None 134101467 Common - mandelate racemase/starvation sensing protein SACE_4937 112 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 134098610 Common - radical SAM domain protein SACE_2037 105 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 134101224 Common folE2 putative GTP cyclohydrolase I SACE_4692 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 134098330 Common - methylase of isopentenylated A37 derivatives in tRNA SACE_1748 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 134103416 Common - transcriptional regulator, XRE family SACE_6990 27 COG1396 HipB, Predicted transcriptional regulators Transcription 134101426 Common - von Willebrand factor, type A SACE_4896 8 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 134103334 Common suhB inositol monophosphatase (extragenic suppressor protein) SACE_6907 152 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 134100105 Common - transcriptional regulator, PadR-like family SACE_3567 51 COG1695 COG1695, Predicted transcriptional regulators Transcription 134101443 Nonpathogen - hypothetical protein SACE_4913 1 None None None 134098713 Common gap glyceraldehyde 3-phosphate dehydrogenase SACE_2143 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 134097077 Common int integrase (recombinase) SACE_0464 44 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 134099715 Common yrhK hypothetical protein SACE_3175 9 None None None 134101150 Common mauD putative methylamine utilization protein SACE_4617 4 None None None 134100108 Nonpathogen - hypothetical protein SACE_3570 1 None None None 134098271 Common - hypothetical protein SACE_1688 5 None None None 134098886 Common - phage-related integrase/recombinase SACE_2322 140 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 134099216 Common - putative ABC transporter substrate-binding protein SACE_2669 120 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 134099643 Common atsD proable arylsulfatase SACE_3101 70 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 134097616 Common - lysine decarboxylase family protein SACE_1020 120 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 134101719 Common - hypothetical protein SACE_5214 35 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 134099235 Common trpE anthranilate synthase component I SACE_2689 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 134099065 Common - translation initiation inhibitor SACE_2508 87 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 134100922 Common lanM2 lantibiotic modifying enzyme SACE_4389 18 COG4403 LcnDR2, Lantibiotic modifying enzyme Defense mechanisms 134102296 Nonpathogen - hypothetical protein SACE_5848 1 None None None 134101090 Common - glycosyl hydrolase, BNR repeat SACE_4557 29 COG4692 COG4692, Predicted neuraminidase (sialidase) Carbohydrate transport and metabolism 134099663 Common - hypothetical protein SACE_3121 97 COG1801 COG1801, Uncharacterized conserved protein Function unknown 134099385 Common cyp7 cytochrome P450 hydroxylase SACE_2842 80 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134099563 Common - hypothetical protein SACE_3021 23 None None None 134097954 Common - integral membrane transporter SACE_1368 90 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 134098496 Common - putative phosphoketolase SACE_1921 65 COG3957 COG3957, Phosphoketolase Carbohydrate transport and metabolism 134098641 Common - hypothetical protein SACE_2071 20 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 134100463 Common cyp51 cytochrome P450 51 SACE_3928 88 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134101169 Common - oxidoreductase SACE_4636 119 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 134101690 Common - hypothetical protein SACE_5182 153 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 134099893 Common - hypothetical protein SACE_3354 27 COG4101 COG4101, Predicted mannose-6-phosphate isomerase Carbohydrate transport and metabolism 134098080 Common - undecaprenyl diphosphate synthase SACE_1494 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 134103777 Common - hypothetical protein SACE_7357 9 None None None 134103516 Nonpathogen - hypothetical protein SACE_7093 4 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 134101271 Nonpathogen - hypothetical protein SACE_4739 1 None None None 134097495 Common fadA3 acetyl-CoA acetyltransferase SACE_0897 187 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 134100250 Common marR regulatory protein, MarR SACE_3714 47 COG1846 MarR, Transcriptional regulators Transcription 134097793 Common - peptidase S58, DmpA SACE_1203 52 COG3191 DmpA, L-aminopeptidase/D-esterase Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134098141 Common - possible membrane protein SACE_1555 71 COG2119 COG2119, Predicted membrane protein Function unknown 134103193 Common - alpha/beta hydrolase fold SACE_6763 45 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134102064 Common soxB sarcosine oxidase beta subunit SACE_5614 113 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 134101498 Common - transposase SACE_4970 21 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134103775 Common - possible membrane protein SACE_7355 14 COG5650 COG5650, Predicted integral membrane protein Function unknown 134100485 Common - hypothetical protein SACE_3950 12 None None None 134101475 Nonpathogen - hypothetical protein SACE_4945 1 None None None 134102667 Common - ribose ABC transporter binding protein SACE_6230 100 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 134097648 Common - NUDIX hydrolase SACE_1052 150 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 134100521 Common - possible transcriptional regulator, TetR family SACE_3986 16 COG1309 AcrR, Transcriptional regulator Transcription 134096974 Common - hypothetical protein SACE_0360 13 None None None 134098700 Common - hypothetical protein SACE_2130 28 COG2808 PaiB, Transcriptional regulator Transcription 134101864 Common - two-component system response regulator SACE_5362 222 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 134103519 Common pstB putative phosphate transport ATP-binding protein SACE_7096 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 134103496 Common - hypothetical protein SACE_7071 4 None None None 134102472 Common cdsA phosphatidate cytidylyltransferase SACE_6034 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 134097052 Common ispD 4-diphosphocytidyl-2C-methyl-D-erythritol synthase SACE_0439 129 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 134101710 Common - putative LacI-family transcriptional regulator SACE_5204 128 COG1609 PurR, Transcriptional regulators Transcription 134103339 Common - metallopeptidase SACE_6912 130 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 134098468 Common - putative transmembrane sugar transport protein SACE_1892 181 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 134100642 Common - ISXo8 transposase SACE_4108 23 COG5659 COG5659, FOG: Transposase DNA replication, recombination, and repair 134102244 Common - hypothetical protein SACE_5796 32 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 134100830 Nonpathogen - hypothetical protein SACE_4297 1 None None None 134098089 Nonpathogen - hypothetical protein SACE_1503 1 None None None 134101691 Nonpathogen - hypothetical protein SACE_5183 1 COG0392 COG0392, Predicted integral membrane protein Function unknown 134097623 Common tag DNA-3-methyladenine glycosylase I SACE_1027 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 134098305 Common - hypothetical protein SACE_1723 9 None None None 134101038 Common - hypothetical protein SACE_4505 3 None None None 134101393 Nonpathogen - hypothetical protein SACE_4863 1 None None None 134099327 Nonpathogen - hypothetical protein SACE_2782 1 None None None 134099833 Common - protein of unknown function DUF1503 SACE_3294 9 None None None 134101556 Common - amidase SACE_5032 219 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 134097446 Common - protein of unknown function DUF820 SACE_0841 32 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 134100538 Common marR regulatory protein, MarR SACE_4003 24 COG1846 MarR, Transcriptional regulators Transcription 134101734 Common - two-component system sensor kinase SACE_5230 44 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 134102506 Common - hypothetical protein SACE_6069 3 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 134103503 Common - integral membrane protein SACE_7078 6 None None None 134099002 Common - hypothetical protein SACE_2440 21 None None None 134099120 Common - TetR-family transcriptional regulator SACE_2565 46 COG1309 AcrR, Transcriptional regulator Transcription 134097988 Nonpathogen - acetyltransferase SACE_1402 5 COG0456 RimI, Acetyltransferases General function prediction only 134098199 Common - putative transposase (second part) SACE_1615 26 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 134097170 Common - hypothetical protein SACE_0559 9 None None None 134102429 Nonpathogen - hypothetical protein SACE_5985 1 None None None 134103156 Common lacZ beta-galactosidase SACE_6726 73 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 134098152 Common lys1 saccharopine dehydrogenase SACE_1566 57 COG3268 COG3268, Uncharacterized conserved protein Function unknown 134097425 Common - TetR-family transcriptional regulator SACE_0820 128 COG1309 AcrR, Transcriptional regulator Transcription 134096851 Common - RNA polymerase sigma-70 factor, ECF family SACE_0234 156 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 134101744 Common - hypothetical protein SACE_5240 5 None None None 134101040 Common - hypothetical protein SACE_4507 5 COG4427 COG4427, Uncharacterized protein conserved in bacteria Function unknown 134097631 Common - uridine kinase SACE_1035 10 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 134101298 Common gnuT,gntP gluconate permease SACE_4766 35 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 134096874 Common appCC oligopeptide ABC transporter (permease) SACE_0259 209 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 134097911 Common - cell wall surface anchor family protein SACE_1324 3 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 134100842 Nonpathogen - hypothetical protein SACE_4309 1 None None None 134101627 Nonpathogen - hypothetical protein SACE_5113 1 None None None 134099675 Common fadE10 putative acyl-CoA dehydrogenase SACE_3133 148 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134097507 Common - possible N-acetylglucosaminylphosphatidylinositol deacetylase SACE_0909 40 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 134098066 Common dnaJ1 chaperone protein SACE_1480 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 134102076 Common - transcriptional regulator, XRE family SACE_5626 6 None None None 134099699 Common - carnitine O-acetyltransferase SACE_3158 7 None None None 134100408 Common dghA glutamate dehydrogenase (NAD(P)+) SACE_3873 177 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 134098584 Common - putative glycosyltransferase SACE_2010 23 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 134099685 Common - aromatic acid symporter, MFS superfamily SACE_3143 94 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134098045 Common mmsB 3-hydroxyisobutyrate dehydrogenase SACE_1459 182 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 134100925 Common - hypothetical protein SACE_4392 10 None None None 134101291 Common - regulatory protein SACE_4759 81 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 134102639 Common padC,yveH phenolic acid decarboxylase SACE_6202 11 COG3479 COG3479, Phenolic acid decarboxylase Secondary metabolites biosynthesis, transport, and catabolism 134098707 Common - hypothetical protein SACE_2137 15 None None None 134100089 Common - selenocysteine-specific translation elongation factor SACE_3551 249 COG3276 SelB, Selenocysteine-specific translation elongation factor Translation, ribosomal structure and biogenesis 134102016 Common - UDP-glucose 6-dehydrogenase SACE_5566 148 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 134100245 Common - DNA binding protein, Ku-like SACE_3709 63 COG1273 COG1273, Uncharacterized conserved protein Function unknown 134102434 Common - penicillin-binding protein, transpeptidase SACE_5990 184 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 134097183 Common - ABC transporter, ATP-binding protein SACE_0573 237 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 134103448 Common - hypothetical protein SACE_7023 5 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 134096814 Nonpathogen - hypothetical protein SACE_0197 1 None None None 134099921 Nonpathogen - hypothetical protein SACE_3382 1 None None None 134102092 Nonpathogen - hypothetical protein SACE_5642 1 None None None 134100614 Nonpathogen - IclR-family regulatory protein SACE_4079 2 COG1414 IclR, Transcriptional regulator Transcription 134103616 Common - ABC transporter ATP-binding protein SACE_7194 247 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 134103536 Common - glycine cleavage T protein (aminomethyl transferase) SACE_7113 114 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 134103367 Common - hypothetical protein SACE_6940 4 None None None 134097218 Common - hypothetical protein SACE_0608 10 COG1834 COG1834, N-Dimethylarginine dimethylaminohydrolase Amino acid transport and metabolism 134099030 Common - DsbA oxidoreductase SACE_2469 88 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 134103754 Common clpX ATP-dependent protease ATP-binding subunit SACE_7334 215 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 134101940 Common - transcriptional regulatory protein SACE_5442 89 COG1309 AcrR, Transcriptional regulator Transcription 134099316 Common - AAA ATPase, central domain protein SACE_2771 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 134097693 Nonpathogen - hypothetical protein SACE_1097 8 None None None 134101135 Common - possible endoribonuclease SACE_4602 31 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 134096992 Common holB DNA polymerase III, delta' subunit SACE_0379 217 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 134098526 Common - hypothetical protein SACE_1951 140 COG0579 COG0579, Predicted dehydrogenase General function prediction only 134099845 Nonpathogen - hypothetical protein SACE_3306 9 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 134097942 Common - drug resistance transporter, EmrB/QacA family SACE_1355 225 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134099725 Common wzz cell surface polysaccharide biosynthesis / chain length determinant protein SACE_3185 26 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 134103607 Nonpathogen - hypothetical protein SACE_7185 1 None None None 134102902 Common - hypothetical protein SACE_6469 20 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 134100753 Common - hypothetical protein SACE_4220 10 None None None 134098651 Common pyrC dihydroorotase SACE_2080 212 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 134102922 Common - hypothetical protein SACE_6489 14 COG2246 COG2246, Predicted membrane protein Function unknown 134099655 Nonpathogen - hypothetical protein SACE_3113 1 None None None 134100987 Common - major facilitator superfamily (MFS) metabolite/H+ symporter SACE_4454 155 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 134098736 Common - hypothetical protein SACE_2166 18 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 134103770 Common ssb single-strand DNA-binding protein SACE_7350 189 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 134101213 Common - putative zinc-binding NADP-dependent dehydrogenase SACE_4681 191 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 134103205 Nonpathogen - hypothetical protein SACE_6776 1 None None None 134097276 Common - cell divisionFtsK/SpoIIIE SACE_0667 95 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 134100712 Common - hypothetical protein SACE_4179 24 COG4552 Eis, Predicted acetyltransferase involved in intracellular survival and related acetyltransferases General function prediction only 134097209 Common - putative heat shock protein, HSP90-family SACE_0599 9 None None None 134102586 Common - hypothetical protein SACE_6149 97 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 134102101 Common - probable oxidoreductase protein, aldo-keto aldolase family SACE_5651 173 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 134099617 Common hypA1 hydrogenase nickel incorporation protein HypA SACE_3075 89 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 134100195 Common - carboxylesterase SACE_3657 56 COG2272 PnbA, Carboxylesterase type B Lipid metabolism 134101300 Common - xylose isomerase domain protein TIM barrel SACE_4768 19 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 134101491 Common - putative IS630 family transposase SACE_4962 7 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 134099129 Nonpathogen - hypothetical protein SACE_2574 1 None None None 134103329 Common nuoB NADH dehydrogenase I chain B SACE_6901 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 134101390 Common - integral membrane transporter SACE_4860 161 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 134102722 Common atpB ATP synthase A chain SACE_6286 199 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 134103170 Common - hypothetical protein SACE_6740 6 None None None 134103324 Common nuoG NADH dehydrogenase subunit G SACE_6896 196 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 134100075 Common - protease SACE_3537 118 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 134102676 Common - putative transcriptional regulator SACE_6239 63 COG1309 AcrR, Transcriptional regulator Transcription 134101166 Common - amino acid ABC transporter permease protein SACE_4633 151 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 134101405 Common - putative maleate cis-trans isomerase SACE_4875 47 COG3473 COG3473, Maleate cis-trans isomerase Secondary metabolites biosynthesis, transport, and catabolism 134103196 Common acpS putative holo-[acyl-carrier protein] synthase SACE_6767 67 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 134096796 Common embC integral membrane indolylacetylinositol arabinosyltransferase EmbC (arabinosylindolylacetylinositol synthase) SACE_0179 5 None None None 134102719 Common atpH ATP synthase delta chain SACE_6283 40 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 134098671 Common - DNA-directed RNA polymerase subunit omega SACE_2101 22 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 134103103 Nonpathogen - hypothetical protein SACE_6673 9 COG1510 COG1510, Predicted transcriptional regulators Transcription 134099166 Common stcD oxidoreductase, FAD/FMN-binding SACE_2617 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 134099966 Common - transcriptional regulator, TetR family SACE_3427 95 COG1309 AcrR, Transcriptional regulator Transcription 134096711 Nonpathogen - hypothetical protein SACE_0093 1 None None None 134099730 Nonpathogen - hypothetical protein SACE_3190 1 None None None 134100632 Common - RNA polymerase, sigma-24 subunit, ECF subfamily SACE_4098 9 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 134101773 Nonpathogen - hypothetical protein SACE_5270 1 COG3311 AlpA, Predicted transcriptional regulator Transcription 134100411 Common - hypothetical protein SACE_3876 18 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 134097501 Nonpathogen - hypothetical protein SACE_0903 1 None None None 134097868 Nonpathogen - hypothetical protein SACE_1281 2 None None None 134099288 Common fadE22 putative acyl-CoA dehydrogenase SACE_2743 144 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134101640 Common - DNA methylase SACE_5130 21 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 134102519 Nonpathogen - PE-PGRS family protein SACE_6082 1 COG4907 COG4907, Predicted membrane protein Function unknown 134102320 Common - methyltransferase SACE_5873 37 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134101602 Nonpathogen - hypothetical protein SACE_5079 1 None None None 134101319 Common - enoyl-CoA hydratase/isomerase SACE_4787 181 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 134099462 Nonpathogen - hypothetical protein SACE_2920 1 None None None 134101886 Common - MaoC-like dehydratase SACE_5384 72 COG2030 MaoC, Acyl dehydratase Lipid metabolism 134100282 Common - transcriptional regulator, HxlR family SACE_3747 105 COG1733 COG1733, Predicted transcriptional regulators Transcription 134102323 Common ycdG xanthine/uracil permease SACE_5876 116 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 134100980 Common pqqB pyrroloquinoline quinone biosynthesis protein PqqB SACE_4447 34 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 134099396 Common whiB1 putative transcriptional regulator (WhiB family) SACE_2853 19 None None None 134097680 Common - hypothetical protein SACE_1084 3 None None None 134100453 Common - dimethylaniline monooxygenase (N-oxide forming) SACE_3918 8 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 134096919 Nonpathogen - hypothetical protein SACE_0305 1 None None None 134097084 Nonpathogen - hypothetical protein SACE_0470 1 None None None 134099636 Common - cold-shock DNA-binding domain protein SACE_3094 182 COG1278 CspC, Cold shock proteins Transcription 134100427 Common - hypothetical protein SACE_3892 18 COG4821 COG4821, Uncharacterized protein containing SIS (Sugar ISomerase) phosphosugar binding domain General function prediction only 134102461 Common arsC arsenate reductase SACE_6023 101 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 134098994 Common - formate dehydrogenase, alpha subunit SACE_2432 216 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 134101049 Nonpathogen - hypothetical protein SACE_4516 1 None None None 134102402 Common - hypothetical protein SACE_5956 25 COG1799 COG1799, Uncharacterized protein conserved in bacteria Function unknown 134099156 Common - hypothetical protein SACE_2601 9 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 134098159 Common - hypothetical protein SACE_1573 13 None None None 134099206 Nonpathogen - possible transcriptional regulator, MerR family SACE_2659 4 COG0789 SoxR, Predicted transcriptional regulators Transcription 134101389 Common - MerR-family transcriptional regulator SACE_4859 150 COG0789 SoxR, Predicted transcriptional regulators Transcription 134097908 Common - probable copper resistance transporter SACE_1321 35 COG3336 COG3336, Predicted membrane protein Function unknown 134102821 Nonpathogen - hypothetical protein SACE_6387 1 None None None 134098234 Common cobU cobinamide kinase / conamide phosphate guanylyltransferase SACE_1651 128 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 134103557 Nonpathogen - hypothetical protein SACE_7135 1 None None None 134099525 Common tnp transposase, ISlxx5 SACE_2983 63 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 134096942 Common - ABC transporter integral membrane protein SACE_0328 14 None None None 134102622 Common - transcriptional regulator, TetR family SACE_6185 46 COG1309 AcrR, Transcriptional regulator Transcription 134101434 Common - transposase, IS4 SACE_4904 46 None None None 134103635 Common ybjK putative DeoR-type transcriptional regulator SACE_7213 18 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 134098190 Common - light-dependent protochlorophyllide reductase SACE_1606 30 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134101807 Common - putative regulator SACE_5304 4 None None None 134103395 Common - lipoprotein SACE_6969 31 None None None 134099039 Common - secreted trypsin-like serine protease SACE_2479 34 COG5640 COG5640, Secreted trypsin-like serine protease Posttranslational modification, protein turnover, chaperones 134101377 Common hutH2 histidine ammonia-lyase SACE_4848 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 134096706 Nonpathogen - hypothetical protein SACE_0088 1 None None None 134102300 Common ftsW bacterial cell division membrane protein SACE_5852 206 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 134099058 Nonpathogen - hypothetical protein SACE_2501 1 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 134100456 Common - putative polysaccharide deacetylase SACE_3921 73 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 134102629 Common - lysine exporter protein (LysE/YggA) SACE_6192 110 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 134100138 Nonpathogen - hypothetical protein SACE_3600 1 None None None 134096677 Common - transcriptional regulator, IclR family SACE_0059 122 COG1414 IclR, Transcriptional regulator Transcription 134103466 Common ctaD cytochrome c oxidase subunit I SACE_7041 167 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 134100339 Common - bifunctional uroporphyrinogen-III synthetase/response regulator domain protein SACE_3804 62 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 134099811 Common crtV methylesterase SACE_3272 13 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 134103576 Common - RNA polymerase ECF sigma factor SACE_7154 96 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 134098226 Common - amino acid permease-associated region SACE_1643 9 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 134102615 Nonpathogen - hypothetical protein SACE_6178 2 None None None 134101250 Common - AraC-family transcriptional regulator SACE_4718 51 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 134102523 Common kdpD sensor histidine kinase SACE_6086 217 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 134102710 Common - acetyltransferase SACE_6274 34 COG0456 RimI, Acetyltransferases General function prediction only 134100552 Common - carbon-monoxide dehydrogenase SACE_4017 104 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 134097887 Nonpathogen - hypothetical protein SACE_1300 1 COG2327 WcaK, Uncharacterized conserved protein Function unknown 134101351 Common oppB oligopeptide ABC transporter, permease SACE_4822 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 134102228 Common cpt carboxypeptidase T precursor SACE_5779 25 COG2866 COG2866, Predicted carboxypeptidase Amino acid transport and metabolism 134098823 Common - hypothetical protein SACE_2254 16 None None None 134098219 Common lipB lipoyltransferase SACE_1636 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 134102654 Common lpqM possible lipoprotein peptidase LpqM SACE_6217 83 COG2321 COG2321, Predicted metalloprotease General function prediction only 134102341 Nonpathogen - hypothetical protein SACE_5894 1 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 134102042 Common - hypothetical protein SACE_5592 11 None None None 134098923 Common - possible Mce family protein SACE_2359 12 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 134097816 Common - secreted trypsin-like serine protease SACE_1227 35 COG5640 COG5640, Secreted trypsin-like serine protease Posttranslational modification, protein turnover, chaperones 134102649 Nonpathogen - putative regulator SACE_6212 4 None None None 134101827 Common - short chain dehydrogenase/reductase SDR SACE_5324 63 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 134102632 Common rnhA,dasF,herA,rnh,sdrA ribonuclease HI SACE_6195 175 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 134096958 Common dapA 5-dehydro-4-deoxyglucarate dehydratase SACE_0344 208 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 134101259 Common - putative two-component system response regulator SACE_4727 151 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 134102510 Nonpathogen - hypothetical protein SACE_6073 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 134097893 Common cdaPSI CDA peptide synthetase I SACE_1306 209 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134102114 Common - integral membrane protein SACE_5664 16 COG2981 CysZ, Uncharacterized protein involved in cysteine biosynthesis Amino acid transport and metabolism 134096724 Common - hypothetical protein SACE_0106 27 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 134097039 Common - MarR-family transcriptional regulator SACE_0426 37 COG1846 MarR, Transcriptional regulators Transcription 134098661 Common - cytochrome P450 monooxygenase SACE_2090 12 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134099888 Common - transcriptional regulator, XRE family SACE_3349 6 None None None 134096737 Common - sodium:solute symporter, SSF SACE_0119 129 COG4147 DhlC, Predicted symporter General function prediction only 134100366 Common - hypothetical protein SACE_3831 10 None None None 134098975 Common - protein of unknown function DUF451 SACE_2413 10 COG2822 COG2822, Predicted periplasmic lipoprotein involved in iron transport Inorganic ion transport and metabolism 134103041 Common ctpA putative cation-transporting P-type ATPase SACE_6611 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 162316925 Common ilvD dihydroxy-acid dehydratase SACE_1280 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 134100889 Common ilvA threonine dehydratase SACE_4356 197 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 134097366 Nonpathogen - hypothetical protein SACE_0760 1 None None None 134102933 Common - membrane-flanked domain protein SACE_6500 12 COG3428 COG3428, Predicted membrane protein Function unknown 134098411 Common - hypothetical protein SACE_1835 19 None None None 134099608 Common - hypothetical protein SACE_3066 7 None None None 134098095 Nonpathogen - hypothetical protein SACE_1509 1 None None None 134102554 Nonpathogen - hypothetical protein SACE_6117 1 None None None 134097123 Common - hypothetical protein SACE_0512 8 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 134101583 Common - C4-dicarboxylate transport system substrate-binding protein SACE_5059 104 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 134101908 Common adc acetoacetate decarboxylase SACE_5407 19 COG4689 Adc, Acetoacetate decarboxylase Secondary metabolites biosynthesis, transport, and catabolism 134098494 Common - two component system response regulator SACE_1919 177 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134099241 Common - putative non-ribosomal peptide synthetase SACE_2695 217 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134099537 Common - Sugar phosphate isomerases/epimerases SACE_2995 55 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 134099947 Common - hypothetical protein SACE_3408 83 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 134100567 Common - hypothetical protein SACE_4032 5 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 134102882 Common tmk thymidylate kinase SACE_6448 11 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 134100129 Common - phosphoglycerate mutase SACE_3591 93 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 134099097 Common - transcriptional regulator, TetR family SACE_2542 20 COG1309 AcrR, Transcriptional regulator Transcription 134100173 Common - probable transposase SACE_3635 25 None None None 134101620 Common - type III restriction enzyme, res subunit SACE_5103 29 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 134097724 Nonpathogen - hypothetical protein SACE_1129 3 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 134100664 Common - ornithine/acetylornithine aminotransferase SACE_4131 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 134097338 Common eryBI beta-D-glucosidase SACE_0732 117 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 134102142 Common - NAD-dependent epimerase/dehydratase SACE_5693 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 134097115 Common - serine protease precursor SACE_0504 10 None None None 134100935 Common - short-chain dehydrogenase/reductase SDR SACE_4402 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134098278 Nonpathogen - metallophosphoesterase SACE_1696 3 COG2129 COG2129, Predicted phosphoesterases, related to the Icc protein General function prediction only 134100188 Common - hypothetical protein SACE_3650 8 None None None 134103586 Common - hypothetical protein SACE_7164 3 None None None 134103185 Common - hypothetical protein SACE_6755 9 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 134103717 Common pdhB2 pyruvate dehydrogenase E1 component beta subunit SACE_7295 195 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 134099866 Common - hypothetical protein SACE_3327 21 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 134098244 Common - methyltransferase SACE_1661 158 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 134101910 Common gcdH2 putative glutaryl-CoA dehydrogenase SACE_5409 156 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134099175 Common - isopentenyl-diphosphate delta-isomerase II 2 SACE_2627 114 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 134099737 Common hutC histidine utilization genes repressor protein SACE_3198 121 COG2188 PhnF, Transcriptional regulators Transcription 134097035 Nonpathogen - hypothetical protein SACE_0422 1 None None None 134099583 Common - possible hydroxymethylglutaryl-CoA lyase SACE_3041 92 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 134103162 Nonpathogen - hypothetical protein SACE_6732 1 COG0011 COG0011, Uncharacterized conserved protein Function unknown 134100999 Common - oxidoreductase, iron-sulfur subunit SACE_4466 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 134097537 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase SACE_0939 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 134100628 Common - hypothetical protein SACE_4094 143 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 134103736 Common - putative ArsR-family transcriptional regulator (partial match) SACE_7314 58 COG1777 COG1777, Predicted transcriptional regulators Transcription 134099559 Common arcB4 putative ornithine cyclodeaminase SACE_3017 26 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 134103596 Common - hypothetical protein SACE_7174 5 None None None 134100023 Common ureC urease subunit alpha SACE_3485 96 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 134099357 Nonpathogen - hypothetical protein SACE_2814 3 COG3224 COG3224, Uncharacterized protein conserved in bacteria Function unknown 134099467 Common - hypothetical protein SACE_2925 8 None None None 134098850 Common - hypothetical protein SACE_2282 2 None None None 134099518 Common - similar to fibrinogen-binding protein SACE_2976 11 None None None 134101077 Common - oxidoreductase SACE_4544 92 COG0778 NfnB, Nitroreductase Energy production and conversion 134097152 Common menC O-succinylbenzoate synthase SACE_0541 28 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 134102861 Common - putative two-component system sensor kinase SACE_6427 95 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 134097650 Common - hypothetical protein SACE_1054 17 COG3402 COG3402, Uncharacterized conserved protein Function unknown 134098874 Nonpathogen - hypothetical protein SACE_2309 1 None None None 134102801 Common - hypothetical protein SACE_6367 23 COG3662 COG3662, Uncharacterized protein conserved in bacteria Function unknown 134100142 Common aacC1 aminoglycoside N3'-acetyltransferase protein SACE_3604 16 COG2746 COG2746, Aminoglycoside N3'-acetyltransferase Defense mechanisms 134103678 Common - tRNA (guanine-N7-)-methyltransferase SACE_7256 179 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 134097626 Common pepA leucine aminopeptidase SACE_1030 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 134098083 Common - hypothetical protein SACE_1497 8 COG3689 COG3689, Predicted membrane protein Function unknown 134102970 Nonpathogen - hypothetical protein SACE_6538 1 None None None 134097981 Nonpathogen - hypothetical protein SACE_1395 1 None None None 134100738 Common cypD bifunctional P-450:NADPH-P450 reductase 1 SACE_4205 121 COG0369 CysJ, Sulfite reductase, alpha subunit (flavoprotein) Inorganic ion transport and metabolism 134099747 Common - malate/L-lactate dehydrogenase SACE_3208 67 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 134102173 Common - hypothetical protein SACE_5724 36 COG5587 COG5587, Uncharacterized conserved protein Function unknown 134100829 Common - putative monooxygenase SACE_4296 49 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 134097558 Common - possible suppressor protein DnaK SACE_0961 13 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 134098072 Common - hypothetical protein SACE_1486 10 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 134102088 Common mutA methylmalonyl-CoA mutase, beta subunit SACE_5638 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 134099505 Common soxA2 sarcosine oxidase SACE_2963 39 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 134098582 Common fusA2 elongation factor G SACE_2008 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 134103313 Common - amidinotransferase SACE_6885 29 COG1834 COG1834, N-Dimethylarginine dimethylaminohydrolase Amino acid transport and metabolism 134096708 Nonpathogen - hypothetical protein SACE_0090 1 None None None 134100575 Common - twin-arginine translocation pathway signal SACE_4040 119 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 134101792 Common - dimethylallyltranstransferase / geranyltranstransferase / geranylgeranyl pyrophosphate synthetase SACE_5289 238 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 134100654 Nonpathogen slyA putative transcriptional regulator, MarR family SACE_4120 1 COG1846 MarR, Transcriptional regulators Transcription 134099771 Common - transcriptional regulator, GntR family SACE_3232 18 COG2188 PhnF, Transcriptional regulators Transcription 134102100 Common - hypothetical protein SACE_5650 12 None None None 134102213 Common soxR transcriptional regulator, MerR family SACE_5764 104 COG0789 SoxR, Predicted transcriptional regulators Transcription 134097922 Nonpathogen - hypothetical protein SACE_1335 1 None None None 134103682 Common - putative ABC transporter ATP-binding subunit SACE_7260 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 134100000 Common srl transcriptional regulator, DeoR family SACE_3462 115 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 134101325 Common - LysR-family transcriptional regulator SACE_4795 191 COG0583 LysR, Transcriptional regulator Transcription 134102525 Common kdpB potassium-transporting ATPase B chain SACE_6088 232 COG2216 KdpB, High-affinity K+ transport system, ATPase chain B Inorganic ion transport and metabolism 134101636 Common - putative ATP-dependent helicase SACE_5126 192 COG1201 Lhr, Lhr-like helicases General function prediction only 134103011 Common - putative sugar ABC transporter ATP-binding protein SACE_6579 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 134103063 Nonpathogen - hypothetical protein SACE_6633 2 None None None 134097196 Nonpathogen - hypothetical protein SACE_0586 2 None None None 134097529 Common - secreted trypsin-like serine protease SACE_0931 34 COG5640 COG5640, Secreted trypsin-like serine protease Posttranslational modification, protein turnover, chaperones 134098783 Common - hypothetical protein SACE_2213 15 None None None 134099267 Nonpathogen - hypothetical protein SACE_2722 1 None None None 134097606 Common - 4Fe-4S ferredoxin, iron-sulfur binding protein SACE_1010 142 COG1146 COG1146, Ferredoxin Energy production and conversion 134102115 Nonpathogen - hypothetical protein SACE_5665 1 None None None 134099692 Common - ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenase SACE_3150 87 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 134096841 Nonpathogen - hypothetical protein SACE_0224 1 None None None 134099540 Common - type I phosphodiesterase/nucleotide pyrophosphatase SACE_2998 20 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 134098473 Common - putative dioxygenase SACE_1898 3 None None None 134103224 Nonpathogen - hypothetical protein SACE_6796 1 None None None 134100034 Common - hypothetical protein SACE_3496 68 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 134103697 Nonpathogen - hypothetical protein SACE_7275 1 None None None 134103022 Common - possible tRNA-processing ribonuclease BN SACE_6591 36 COG1295 Rbn, Predicted membrane protein Function unknown 134103673 Common phnL ABC transporter, ATP binding protein SACE_7251 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 134099523 Nonpathogen - hypothetical protein SACE_2981 1 None None None 134100154 Nonpathogen - hypothetical protein SACE_3616 3 None None None 134100241 Common - transcriptional regulator, AraC family SACE_3703 116 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 134099481 Common - hypothetical protein SACE_2939 115 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 134103620 Common - probable multidrug resistance protein SACE_7198 28 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134098027 Nonpathogen - hypothetical protein SACE_1441 1 None None None 134098929 Nonpathogen - integral membrane protein SACE_2365 2 None None None 134098457 Common - ABC transporter protein, ATP binding component SACE_1881 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 134097342 Nonpathogen - hypothetical protein SACE_0736 1 None None None 134101590 Common - hypothetical protein SACE_5067 9 COG5485 COG5485, Predicted ester cyclase General function prediction only 134097456 Common - plasmid maintenance system antidote protein SACE_0851 89 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 134100484 Nonpathogen - hypothetical protein SACE_3949 3 None None None 134096698 Common - possible glycine betaine/carnitine/choline binding protein precursor SACE_0080 90 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 134099260 Common - probable transcriptional regulator, LytR family SACE_2715 63 COG1316 LytR, Transcriptional regulator Transcription 134101529 Nonpathogen - hypothetical protein SACE_5001 1 None None None 134100474 Common - bicyclomycin resistance protein TcaB SACE_3939 165 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134102956 Common - lactate 2-monooxygenase SACE_6523 111 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 134102287 Common - putative sugar ABC transporter permease protein SACE_5839 144 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 134102564 Common thiL putative thiamine monophosphate kinase SACE_6127 195 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 134099914 Common - helix-turn-helix motif SACE_3375 7 COG1396 HipB, Predicted transcriptional regulators Transcription 134100055 Common pcaR transcriptional regulator, IclR family SACE_3517 121 COG1414 IclR, Transcriptional regulator Transcription 134101015 Common - hypothetical protein SACE_4482 37 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 134100374 Common - hypothetical protein SACE_3839 3 None None None 134097852 Common - (2Fe-2S)-binding protein SACE_1263 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 134098716 Common secG preprotein translocase subunit SecG SACE_2146 7 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 134102069 Common fhs formate--tetrahydrofolate ligase SACE_5619 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 134102330 Common - N-acetylglutamate synthase SACE_5883 94 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 134096801 Common - hypothetical protein SACE_0184 12 None None None 134099140 Common - transcriptional regulator, GntR family SACE_2585 138 COG1802 GntR, Transcriptional regulators Transcription 134101530 Common - bifunctional deaminase-reductase-like protein SACE_5002 25 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 134101056 Common adpA AraC-family transcriptional regulator SACE_4523 136 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 134099740 Common - hypothetical protein SACE_3201 4 None None None 134096828 Nonpathogen - hypothetical protein SACE_0211 1 None None None 134098763 Common - putative peptide transport system secreted peptide binding protein SACE_2193 204 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 134096686 Nonpathogen - hypothetical protein SACE_0068 1 None None None 134099925 Common uspA1 putative universal stress protein SACE_3386 119 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 134096803 Common embB arabinosyl transferase SACE_0186 5 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 134099237 Common - methionyl-tRNA formyltransferase SACE_2691 226 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 134101174 Common lmrB lincomycin resistance protein SACE_4641 197 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134102281 Common - pyridoxal-5'-phosphate dependent enzyme SACE_5833 198 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 134097236 Common - hypothetical tRNA/rRNA methyltransferase Rv0881 SACE_0626 213 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 134100384 Common - LysR-family transcriptional regulator SACE_3849 167 COG0583 LysR, Transcriptional regulator Transcription 134097669 Nonpathogen - hypothetical protein SACE_1073 3 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 134101329 Nonpathogen - hypothetical protein SACE_4800 1 None None None 134101684 Nonpathogen - hypothetical protein SACE_5176 1 None None None 134102786 Common pon1 penicillin-binding protein 1 SACE_6352 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 134103212 Common - hypothetical protein SACE_6783 5 None None None 134098290 Common aroG phospho-2-dehydro-3-deoxyheptonate aldolase SACE_1708 73 COG3200 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 134098065 Common hrcA heat-inducible transcription repressor SACE_1479 151 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 134101229 Common - transcriptional regulator SACE_4697 67 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 134102818 Common - ABC transporter protein, ATP-binding component SACE_6384 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 134101816 Common ampC2 beta-lactamase precursor SACE_5313 144 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 134097679 Common - hypothetical protein SACE_1083 82 COG2321 COG2321, Predicted metalloprotease General function prediction only 134102990 Common - chitinase II SACE_6558 41 COG3325 ChiA, Chitinase Carbohydrate transport and metabolism 134103015 Common sdhA succinate dehydrogenase flavoprotein subunit SACE_6584 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 134101242 Common - carboxypeptidase G2 SACE_4710 101 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 134100991 Common - hypothetical protein SACE_4458 6 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 134098018 Common - hypothetical protein SACE_1432 72 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 134097713 Nonpathogen - hypothetical protein SACE_1118 4 None None None 134098758 Common - transcriptional regulator SACE_2188 11 None None None 134098293 Common - transcriptional regulatory protein SACE_1711 15 None None None 134103561 Nonpathogen - hypothetical protein SACE_7139 2 None None None 134101289 Common - putative acetyltransferase SACE_4757 27 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 134102558 Common - GntR-family transcriptional regulator SACE_6121 20 COG1725 COG1725, Predicted transcriptional regulators Transcription 134099186 Common dgoK 2-dehydro-3-deoxygalactonate kinase SACE_2638 41 COG3734 DgoK, 2-keto-3-deoxy-galactonokinase Carbohydrate transport and metabolism 134097475 Nonpathogen - hypothetical protein SACE_0875 1 None None None 134098914 Common - regulatory protein SACE_2350 15 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 134102059 Common padAd2 phthalate dioxygenase ferredoxin reductase subunit SACE_5609 149 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 134099595 Common - putative transcriptional regulator SACE_3053 82 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134097211 Common - multidrug ABC transporter, ATP-binding protein SACE_0601 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 134097322 Common eryCIV eryCIV NDP-6-deoxyhexose 3,4-dehydratase SACE_0716 193 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 134100879 Nonpathogen - hypothetical protein SACE_4346 3 None None None 134099274 Common - hypothetical protein SACE_2729 19 None None None 134101537 Common - hypothetical protein SACE_5009 2 None None None 134098100 Common - hypothetical protein SACE_1514 8 COG2879 COG2879, Uncharacterized small protein Function unknown 134098847 Common - probable Xaa-Pro dipeptidase SACE_2279 248 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 134097180 Common - probable ABC molybdate transporter, substrate binding protein SACE_0570 14 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 134099285 Common echA12 putative enoyl-CoA hydratase/isomerase family protein SACE_2740 184 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 134102127 Common pdhD dihydrolipoamide dehydrogenase SACE_5677 245 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 134098830 Nonpathogen - hypothetical protein SACE_2261 1 None None None 134101358 Common - ABC transporter, substrate binding protein (sugar) SACE_4829 44 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 134102317 Common - protein of unknown function DUF58 SACE_5870 45 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 134102963 Common - hypothetical protein SACE_6530 109 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 134098904 Common - oxidoreductase, aldo/keto reductase family SACE_2340 180 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 134096853 Nonpathogen - hypothetical protein SACE_0236 1 None None None 134101522 Common - integral membrane protein SACE_4994 23 COG5500 COG5500, Predicted integral membrane protein Function unknown 134099818 Common - FMNH2-utilizing oxygenase SACE_3279 68 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 134100392 Common fadD36 acyl-CoA synthetase SACE_3857 222 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134101345 Nonpathogen - hypothetical protein SACE_4816 3 None None None 134103798 Common - NUDIX hydrolase SACE_7378 79 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 134100080 Common paaK phenylacetate-CoA ligase SACE_3542 121 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 134103038 Common - regulator SACE_6608 6 None None None 134102627 Common plsC7 1-acylglycerol-3-phosphate O-acyltransferase SACE_6190 104 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 134103003 Common - RNA polymerase, sigma-70 factor, ECF subfamily SACE_6571 15 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 134099301 Common - short-chain dehydrogenase/reductase SDR SACE_2756 233 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134101502 Common - putative phosphotransferase SACE_4974 22 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 134097551 Common sbcC putative ATP-dependent dsDNA exonuclease SACE_0953 105 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 134099784 Nonpathogen - hypothetical protein SACE_3245 1 COG3428 COG3428, Predicted membrane protein Function unknown 134097941 Nonpathogen - hypothetical protein SACE_1354 3 None None None 134097963 Nonpathogen - hypothetical protein SACE_1377 4 COG4907 COG4907, Predicted membrane protein Function unknown 134100009 Common - S-adenosylmethionine (SAM)-dependent methyltransferase SACE_3471 70 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134098207 Common - integral membrane protein SACE_1624 16 None None None 134100694 Common - ABC sugar transporter, permease component SACE_4161 148 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 134097336 Common eryF 6-deoxyerythronolide B hydroxylase (6-DEB hydroxylase) SACE_0730 88 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134099762 Common - transcriptional regulator, TetR family SACE_3223 32 None None None 134100117 Common tnp transposase, ISlxx5 SACE_3579 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 134096830 Nonpathogen - hypothetical protein SACE_0213 1 None None None 134100161 Common - glycosyl hydrolase SACE_3623 64 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 134101878 Common glxR 2-hydroxy-3-oxopropionate reductase SACE_5376 168 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 134097017 Common - putative integral membrane protein SACE_0404 31 COG2339 COG2339, Predicted membrane protein Function unknown 134100691 Nonpathogen - hypothetical protein SACE_4158 1 None None None 134096883 Common - transcriptional regulator, XRE family SACE_0268 8 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 134098834 Common helY putative ATP-dependent RNA helicase SACE_2265 96 COG4581 COG4581, Superfamily II RNA helicase DNA replication, recombination, and repair 134096741 Common - rhodanese-like SACE_0123 139 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 134100811 Common - oxygenase (secreted protein) SACE_4278 10 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 134098784 Common - Transposase SACE_2214 51 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 134100536 Common pptA2 phosphopantetheinyl transferase SACE_4001 31 COG2977 EntD, Phosphopantetheinyl transferase component of siderophore synthetase Secondary metabolites biosynthesis, transport, and catabolism 134100399 Common - transcriptional regulator, TetR family SACE_3864 78 COG1309 AcrR, Transcriptional regulator Transcription 134097271 Common - cytosine deaminase or related metal-dependent hydrolase SACE_0662 159 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 134097821 Common allR DNA-binding transcriptional regulator SACE_1232 124 COG1414 IclR, Transcriptional regulator Transcription 134103486 Nonpathogen - hypothetical protein SACE_7061 1 None None None 134102532 Common - two-component system, response regulator SACE_6095 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 134097516 Nonpathogen - hypothetical protein SACE_0918 1 None None None 134098564 Nonpathogen - hypothetical protein SACE_1990 2 None None None 134099539 Common - hypothetical protein SACE_2997 11 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 134099641 Common - transcriptional regulator, LysR family SACE_3099 190 COG0583 LysR, Transcriptional regulator Transcription 134096872 Common - dipeptide ABC transporter substrate-binding protein SACE_0257 201 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 134101511 Common - putative monooxygenase SACE_4983 7 None None None 134102107 Nonpathogen - hypothetical protein SACE_5657 1 None None None 134099701 Common - hypothetical protein SACE_3160 10 None None None 134098842 Common fruB putative 6-phosphofructokinase SACE_2273 88 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 134098255 Common - ABC sulfonate transport system, permease protein SACE_1672 8 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 134103113 Common - chorismate mutase SACE_6683 9 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 134098373 Common - hypothetical protein SACE_1793 19 None None None 134102960 Common - hypothetical protein SACE_6527 25 None None None 134100674 Common - type I modular polyketide synthase SACE_4141 210 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134097086 Nonpathogen - hypothetical protein SACE_0472 1 COG2188 PhnF, Transcriptional regulators Transcription 134102724 Common rfe undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase SACE_6288 218 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 134096798 Nonpathogen - dolichyl-phosphate beta-D-mannosyltransferase SACE_0181 2 COG2246 COG2246, Predicted membrane protein Function unknown 134101141 Common - probable 3-isopropylmalate dehydrogenase SACE_4608 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 134099337 Common - MutT-like domain protein SACE_2792 64 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 134102868 Common - putative bacteriophage protein SACE_6434 108 COG2135 COG2135, Uncharacterized conserved protein Function unknown 134101029 Common - FAD dependent oxidoreductase SACE_4496 180 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 134102893 Common manB phosphomannomutase/phosphoglucomutase SACE_6460 239 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 134102466 Common - iron ABC transporter ATP-binding protein SACE_6028 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 134103652 Common - integral membrane transport protein SACE_7230 82 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134103379 Common - hypothetical protein SACE_6953 5 None None None 134098050 Common echA21 putative enoyl-CoA hydratase/isomerase family protein SACE_1464 180 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 134100977 Common - hypothetical protein SACE_4444 26 COG3339 COG3339, Uncharacterized conserved protein Function unknown 134102900 Common - F420-0--gamma-glutamyl ligase SACE_6467 56 COG1478 COG1478, Uncharacterized conserved protein Function unknown 134102227 Common hisD histidinol dehydrogenase SACE_5778 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 134101204 Common mmsA1 methylmalonate-semialdehyde dehydrogenase (acylating) SACE_4672 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 134098798 Common - probable multidrug resistance transporter, MFS superfamily SACE_2229 31 None None None 134099053 Common - transcriptional regulator, MarR family SACE_2496 54 COG1846 MarR, Transcriptional regulators Transcription 134102255 Nonpathogen - hypothetical protein SACE_5807 1 None None None 134099279 Common - possible fumarate reductase SACE_2734 63 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 134099400 Nonpathogen - hypothetical protein SACE_2857 3 None None None 134099656 Common - short-chain dehydrogenase/reductase SDR SACE_3114 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134100501 Common - amino acid ABC transporter, permease protein SACE_3966 178 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 134098605 Common - beta-lactamase-like protein SACE_2031 215 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 134101460 Common - sodium/hydrogen antiporter SACE_4930 41 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 134101837 Common - hypothetical protein SACE_5335 5 COG5373 COG5373, Predicted membrane protein Function unknown 134099597 Nonpathogen - hypothetical protein SACE_3055 1 None None None 134100112 Common - probable UDP-N-acetylmuramoylalanine--D-glutamate ligase SACE_3574 45 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 134098336 Common hflX GTP-binding protein SACE_1754 219 COG2262 HflX, GTPases General function prediction only 134100852 Common aspB aspartate aminotransferase SACE_4319 63 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 134097763 Common sdhB1 fumarate reductase iron-sulfur subunit SACE_1171 201 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 134101215 Common bioB biotin synthase SACE_4683 185 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 134099409 Common rifI aminoquinate/shkimate dehydrogenase SACE_2867 162 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 134097228 Common - integral membrane cytochrome biogenesis protein SACE_0618 33 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 134103602 Common fba,fda fructose-bisphosphate aldolase SACE_7180 168 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 134098896 Nonpathogen - hypothetical protein SACE_2332 2 None None None 134100277 Common - twin-arginine translocation pathway signal SACE_3742 75 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 134098777 Common - ABC transporter, ATP-binding component SACE_2207 235 COG1119 ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA Inorganic ion transport and metabolism 134100147 Common - GCN5-related N-acetyltransferase SACE_3609 30 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 134103801 Common - integral membrane protein MviN SACE_7381 10 None None None 134097391 Common - multidrug transporter, Dha2 family of MFS superfamily SACE_0785 151 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134097403 Common - ABC transport system ATP-binding protein SACE_0797 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 134096773 Nonpathogen - hypothetical protein SACE_0156 1 None None None 134096906 Common - transcriptional regulator, LuxR family SACE_0292 14 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134101965 Common - hypothetical protein SACE_5483 8 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 134102879 Common lpqB lipoprotein SACE_6445 17 None None None 134102746 Common - pyridine nucleotide-disulphide oxidoreductase,class II SACE_6311 87 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 134102701 Common - NUDIX hydrolase SACE_6265 104 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 134102685 Common - dihydroxyacetone kinase, DhaK subunit SACE_6248 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 134103235 Common rpmJ 50S ribosomal protein L36 SACE_6807 123 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 134098148 Common - endonuclease SACE_1562 27 None None None 134100261 Common - dehydrogenase SACE_3726 47 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134101127 Common lacG ABC transporter sugar permease SACE_4594 147 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 134097418 Common - NAD-dependent epimerase/dehydratase family protein SACE_0813 58 COG2910 COG2910, Putative NADH-flavin reductase General function prediction only 134099778 Common slpD proteinase (secreted protein) SACE_3239 38 None None None 134102264 Nonpathogen - hypothetical protein SACE_5816 1 COG1522 Lrp, Transcriptional regulators Transcription 134097486 Common - hypothetical protein SACE_0888 46 None None None 134098325 Common gluD glutamate permease SACE_1743 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 134102206 Common - pyridoxamine 5'-phosphate oxidase-related,FMN-binding protein SACE_5757 13 COG3871 COG3871, Uncharacterized stress protein (general stress protein 26) General function prediction only 134097873 Common - ABC transporter ATP-binding protein SACE_1286 233 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 134102716 Common atpD F0F1 ATP synthase subunit beta SACE_6280 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 134100958 Common pqqE pyrroloquinoline quinone biosynthesis protein PqqE SACE_4425 179 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 134100442 Common - hypothetical protein SACE_3907 7 COG0627 COG0627, Predicted esterase General function prediction only 134098436 Common - 2-dehydropantoate 2-reductase SACE_1860 52 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 134098944 Common - putative two-component system sensor kinase SACE_2380 141 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 134101507 Nonpathogen - hypothetical protein SACE_4979 1 None None None 134098114 Common - hypothetical protein SACE_1528 5 None None None 134101414 Common pucR transcriptional regulator SACE_4884 36 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 134100797 Nonpathogen - hypothetical protein SACE_4264 1 None None None 134100950 Common - N5,N10-methylenetetrahydromethanopterin reductase-related protein SACE_4417 60 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 134102752 Common lacC tagatose-6-phosphate kinase SACE_6317 91 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 134100314 Common - transcriptional regulator, ArsR family SACE_3779 113 COG1777 COG1777, Predicted transcriptional regulators Transcription 134097286 Common - glycosyl transferase, group 1 SACE_0679 224 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 134100347 Common - hypothetical protein SACE_3812 3 None None None 134098344 Common - ribonucleotide reductase regulator NrdR-like protein SACE_1763 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 134099964 Nonpathogen - hypothetical protein SACE_3425 1 None None None 134099665 Common - antibiotic biosynthesis monooxygenase SACE_3123 12 COG1359 COG1359, Uncharacterized conserved protein Function unknown 134098057 Nonpathogen - hypothetical protein SACE_1471 1 None None None 134097070 Common - hypothetical protein SACE_0457 10 COG3766 COG3766, Predicted membrane protein Function unknown 134101650 Common - hypothetical protein SACE_5141 5 None None None 134101379 Common - IS1647-like transposase SACE_4850 36 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134098187 Common - putative glutathione S-transferase SACE_1603 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 134097928 Common aldA aldehyde dehydrogenase SACE_1341 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 134098287 Common - two component system sensor kinase SACE_1705 112 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 134102988 Nonpathogen - hypothetical protein SACE_6556 1 None None None 134098030 Common - glyoxalase/bleomycin resistance protein/dioxygenase SACE_1444 11 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 134098487 Common aprA putative alkaline serine protease SACE_1912 123 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 134102033 Common whiB3 putative transcriptional regulator (WhiB family) SACE_5583 19 None None None 134097973 Common folC folylpolyglutamate synthase SACE_1387 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 134100342 Nonpathogen - hypothetical protein SACE_3807 1 None None None 134099014 Common - hypothetical protein SACE_2452 19 None None None 134098359 Common acuC acetoin dehydrogenase SACE_1779 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 134100870 Common - transcriptional regulator, GntR family SACE_4337 18 COG1802 GntR, Transcriptional regulators Transcription 134103722 Nonpathogen - hypothetical protein SACE_7300 1 None None None 134098812 Common - peptidase M50 SACE_2243 49 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 134098573 Common - transposase for IS3517 SACE_1999 11 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 134100986 Common - transcriptional regulator, RpiR family SACE_4453 39 COG1737 RpiR, Transcriptional regulators Transcription 134097426 Common - transcriptional regulator, IclR family SACE_0821 117 COG1414 IclR, Transcriptional regulator Transcription 134101906 Common - fatty acid-CoA racemase SACE_5405 115 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 134096767 Common - heat shock protein HSP20 SACE_0150 131 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 134102538 Common rpmF 50S ribosomal protein L32 SACE_6101 75 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 134099821 Common - 56kDa selenium binding SACE_3282 18 COG5276 COG5276, Uncharacterized conserved protein Function unknown 134100803 Common - integral membrane protein SACE_4270 7 None None None 134099473 Nonpathogen - hypothetical protein SACE_2931 1 None None None 134097434 Nonpathogen - hypothetical protein SACE_0829 1 None None None 134102797 Common fadA acetyl-CoA acetyltransferase SACE_6363 171 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 134098557 Nonpathogen - integral membrane protein SACE_1983 1 None None None 134096965 Common estC esterase SACE_0351 19 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134103034 Common - two component system histidine kinase SACE_6604 144 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 134102418 Common - D-isomer specific 2-hydroxyacid dehydrogenase family protein SACE_5972 177 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 134103354 Common - integral membrane protein SACE_6927 2 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 134098881 Common - transposase SACE_2316 64 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134101613 Common - IS629 ORF2 SACE_5092 74 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 134102080 Common - DEAD/DEAH box helicase-like SACE_5630 127 COG4581 COG4581, Superfamily II RNA helicase DNA replication, recombination, and repair 134103161 Common - xylose isomerase domain protein TIM barrel SACE_6731 78 COG3622 Hfi, Hydroxypyruvate isomerase Carbohydrate transport and metabolism 134097642 Common - ABC sugar transporter, permease component SACE_1046 167 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 134097505 Common greA transcription elongation factor G SACE_0907 204 COG0782 GreA, Transcription elongation factor Transcription 134097956 Nonpathogen - hypothetical protein SACE_1370 2 None None None 134098348 Common - hypothetical protein SACE_1767 12 None None None 134097189 Nonpathogen - hypothetical protein SACE_0579 1 None None None 134099528 Common - xylose isomerase domain protein TIM barrel SACE_2986 60 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 134102268 Common pntB putative pyridine nucleotide transhydrogenase beta subunit SACE_5820 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 134096623 Common gnd2 6-phosphogluconate dehydrogenase-like protein SACE_0004 186 COG1023 Gnd, Predicted 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 134097145 Common - VWA containing CoxE-like protein SACE_0534 34 COG3552 CoxE, Protein containing von Willebrand factor type A (vWA) domain General function prediction only 134099988 Common - enoyl-CoA hydratase/isomerase SACE_3450 175 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 134103140 Common - hypothetical protein SACE_6710 4 COG3889 COG3889, Predicted solute binding protein General function prediction only 134099509 Common cspA PS1 protein SACE_2967 12 COG5479 COG5479, Uncharacterized protein potentially involved in peptidoglycan biosynthesis Cell envelope biogenesis, outer membrane 134099891 Nonpathogen - hypothetical protein SACE_3352 1 None None None 134100702 Common - esterase/lipase SACE_4169 82 COG0657 Aes, Esterase/lipase Lipid metabolism 134098128 Common - hypothetical protein SACE_1542 27 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 134101005 Common - NAD-dependent epimerase/dehydratase SACE_4472 54 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 134102382 Common - transcriptional regulator, TetR family SACE_5935 81 COG1309 AcrR, Transcriptional regulator Transcription 134096821 Common - probable aminopeptidase SACE_0204 59 COG2234 Iap, Predicted aminopeptidases General function prediction only 134097013 Common folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase SACE_0400 144 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 134097248 Common ureG urease accessory protein SACE_0638 127 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 134099309 Common - alpha/beta hydrolase fold SACE_2764 4 COG2267 PldB, Lysophospholipase Lipid metabolism 134096860 Nonpathogen - hypothetical protein SACE_0244 1 None None None 134098377 Common csd cysteine desulfurase SACE_1797 218 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 134101891 Common - probable NADPH:quinone reductase SACE_5389 185 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 134100700 Common fadH 2,4-dienoyl-CoA reductase (NADPH) SACE_4167 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 134097295 Common - SSS sodium solute transporter superfamily SACE_0688 127 COG4147 DhlC, Predicted symporter General function prediction only 134101231 Common - transcriptional regulator, LysR family SACE_4699 83 COG0583 LysR, Transcriptional regulator Transcription 134097721 Nonpathogen - hypothetical protein SACE_1126 1 None None None 134097831 Common cyp25 cytochrome P450 SACE_1242 71 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134100401 Common - putative 3-hydroxyacyl-CoA dehydrogenase SACE_3866 139 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 134102917 Common - DoxX family protein SACE_6484 9 COG2259 COG2259, Predicted membrane protein Function unknown 134098746 Common - putative ABC transporter ATP-binding protein SACE_2176 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 134103658 Common - lysine exporter protein (LysE/YggA) SACE_7236 113 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 134101941 Nonpathogen - hypothetical protein SACE_5443 6 COG1510 COG1510, Predicted transcriptional regulators Transcription 134101346 Nonpathogen - integral membrane protein SACE_4817 2 None None None 134098417 Common - antibiotic biosynthesis monooxygenase SACE_1841 16 None None None 134100839 Common pteA1 modular polyketide synthase SACE_4306 218 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134101309 Common - Alkylhydroperoxidase AhpD core domain SACE_4777 74 COG2128 COG2128, Uncharacterized conserved protein Function unknown 134099857 Common - possible esterase SACE_3318 28 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134097597 Nonpathogen - hypothetical protein SACE_1001 3 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 134099291 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase SACE_2746 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134099797 Common - thioesterase involved in non-ribosomal peptide biosynthesis SACE_3258 51 COG3208 GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 134100725 Common - response regulator, two-component system SACE_4192 184 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134099758 Common - AMP-dependent synthetase and ligase SACE_3219 191 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134102423 Common gdh glutamate dehydrogenase SACE_5979 167 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 134099423 Common wrbA flavodoxin/nitric oxide synthase SACE_2881 109 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 134099416 Common aroH phospho-2-dehydro-3-deoxyheptonate aldolase SACE_2874 73 COG3200 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 134103689 Nonpathogen - hypothetical protein SACE_7267 3 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 134099850 Common - hypothetical protein SACE_3311 13 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 134099879 Common - hypothetical protein SACE_3340 27 COG3222 COG3222, Uncharacterized protein conserved in bacteria Function unknown 134101568 Common - ABC transport protein, ATP-binding component SACE_5044 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 134102329 Common - hypothetical protein SACE_5882 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 134097263 Common - ABC transporter (permease) (Na+ exclusion) SACE_0654 18 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 134098309 Nonpathogen - hypothetical protein SACE_1727 1 None None None 134102873 Common - protein of unknown function UPF0089 SACE_6439 28 None None None 134100849 Common - hypothetical protein SACE_4316 5 None None None 134103287 Common mce4E MCE family protein SACE_6859 48 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 134097454 Common - peptidase S10, serine carboxypeptidase SACE_0849 37 COG2939 COG2939, Carboxypeptidase C (cathepsin A) Amino acid transport and metabolism 134099433 Common - transcriptional regulator (TetR family) SACE_2891 20 COG1309 AcrR, Transcriptional regulator Transcription 134100867 Common odc ornithine decarboxylase SACE_4334 207 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 134103272 Common - hypothetical protein SACE_6844 58 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 134099344 Common - transcriptional regulator, MarR family SACE_2799 145 COG1733 COG1733, Predicted transcriptional regulators Transcription 134101036 Nonpathogen - hypothetical protein SACE_4503 1 None None None 134102709 Nonpathogen - acetyltransferase SACE_6273 4 None None None 134103254 Common rplN 50S ribosomal protein L14 SACE_6826 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 134098965 Common - hypothetical protein SACE_2403 12 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 134102741 Common rhtB homoserine/threonine efflux protein SACE_6306 79 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 134103817 Common rpmH 50S ribosomal protein L34 SACE_7397 5 None None None 134099621 Common - LysR-family transcriptional regulator SACE_3079 190 COG0583 LysR, Transcriptional regulator Transcription 134099022 Common - hypothetical protein SACE_2460 8 None None None 134096658 Common pabA putative p-aminobenzoate synthase glutamine amidotransferase SACE_0040 236 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 134097652 Common - hypothetical protein SACE_1056 14 COG3857 AddB, ATP-dependent nuclease, subunit B DNA replication, recombination, and repair 134098037 Common - hypothetical protein SACE_1451 78 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 134097804 Common - large ATP-binding protein SACE_1214 23 COG5635 COG5635, Predicted NTPase (NACHT family) Signal transduction mechanisms 134102548 Nonpathogen - hypothetical protein SACE_6111 1 None None None 134102943 Common - hypothetical protein SACE_6510 5 None None None 134099959 Common - N5,N10-methylene-tetrahydromethanopterin reductase SACE_3420 39 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 134097004 Common ppa putative inorganic pyrophosphatase SACE_0391 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 134103708 Common - putative ABC transporter substrate-binding protein SACE_7286 183 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 134098401 Common cotA,pig spore coat protein (outer) SACE_1822 93 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 134100526 Common - transcriptional regulator, LysR family SACE_3991 190 COG0583 LysR, Transcriptional regulator Transcription 134098891 Common matC dicarboxylate-carrier protein SACE_2327 17 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 134097062 Nonpathogen - hypothetical protein SACE_0449 1 None None None 134098952 Common - hypothetical protein SACE_2388 5 None None None 134101975 Common - serine protease (membrane protein) SACE_5519 102 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 134102609 Nonpathogen - hypothetical protein SACE_6172 1 None None None 134103633 Common - lipoprotein SACE_7211 5 COG3595 COG3595, Uncharacterized conserved protein Function unknown 134103479 Common - Xaa-Pro dipeptidase SACE_7054 131 COG1739 COG1739, Uncharacterized conserved protein Function unknown 134099556 Common nrps4 non-ribosomal peptide synthetase SACE_3014 25 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 134097819 Common - sugar kinase, possible phosphofructokinase SACE_1230 21 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 134097737 Common - flavoprotein SACE_1142 47 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 134097921 Common - HNH endonuclease SACE_1334 94 COG1403 McrA, Restriction endonuclease Defense mechanisms 134101238 Common - transcriptional regulator, XRE family SACE_4706 41 COG1396 HipB, Predicted transcriptional regulators Transcription 134098955 Common - creatininase SACE_2391 86 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 134103362 Common hemL glutamate-1-semialdehyde 2,1-aminomutase SACE_6935 235 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 134097759 Nonpathogen - hypothetical protein SACE_1167 1 None None None 134102834 Common - protein of unknown function DUF899,thioredoxin-like SACE_6400 27 COG4312 COG4312, Uncharacterized protein conserved in bacteria Function unknown 134099145 Nonpathogen - hypothetical protein SACE_2590 1 None None None 134103122 Common - LysR-family transcriptional regulator SACE_6692 158 COG0583 LysR, Transcriptional regulator Transcription 134098688 Common - OsmC-like protein SACE_2118 10 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 134096981 Common - type II secretion system protein SACE_0368 3 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 134100769 Common - hypothetical protein SACE_4236 5 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 134097109 Common - 3-oxoacyl-[acyl-carrier protein] reductase SACE_0496 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134100308 Common - hypothetical protein SACE_3773 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 134097785 Common - hypothetical protein SACE_1195 16 None None None 134099515 Common - putative oxidoreductase, short-chain dehydrogenase/reductase family SACE_2973 98 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134100637 Common rhaB putative rhamnose kinase SACE_4103 52 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 134101674 Common - isochorismatase hydrolase SACE_5166 93 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 134102338 Common plsC 1-acylglycerol-3-phosphate O-acyltransferase SACE_5891 55 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 134099294 Common - hypothetical protein SACE_2749 4 None None None 134097992 Common - ribonuclease, Rne/Rng family SACE_1406 184 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 134099835 Common proP proline/betaine transporter SACE_3296 169 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134098174 Common - putative sugar transport membrane protein SACE_1588 160 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 134097930 Common - hypothetical protein SACE_1343 8 COG2849 COG2849, Uncharacterized protein conserved in bacteria Function unknown 134097978 Nonpathogen - hypothetical protein SACE_1392 1 None None None 134096673 Nonpathogen - hypothetical glycine-rich protein SACE_0055 1 None None None 134103472 Common - probable sugar efflux transporter, MFS superfamily SACE_7047 129 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134098008 Common - transcriptional regulator, XRE family SACE_1422 6 None None None 134101497 Common - hypothetical protein SACE_4969 29 COG3211 PhoX, Predicted phosphatase General function prediction only 134098143 Common - DNA modification methylase M.NGOI SACE_1557 45 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 134101841 Common - multi-domain regulatory protein SACE_5339 31 COG3903 COG3903, Predicted ATPase General function prediction only 134098197 Common glnA2 glutamine synthetase SACE_1613 223 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 134097431 Common mfd transcription-repair coupling factor SACE_0826 231 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 134102568 Common - putative transcriptional regulator SACE_6131 144 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 134097523 Common - binding-protein-dependent transport systems membrane component SACE_0925 157 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 134102856 Common entD phosphoglycerate mutase family protein SACE_6422 142 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 134098819 Common - hypothetical protein SACE_2250 14 None None None 134099801 Common - hypothetical protein SACE_3262 20 COG3595 COG3595, Uncharacterized conserved protein Function unknown 134101146 Common - hypothetical protein SACE_4613 73 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 134103072 Nonpathogen - hypothetical protein SACE_6642 4 None None None 134103388 Common - xylose isomerase-like TIM barrel SACE_6962 23 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 134098320 Common - phosphatase SACE_1738 21 COG0546 Gph, Predicted phosphatases General function prediction only 134103115 Common - D-beta-hydroxybutyrate dehydrogenase SACE_6685 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134101702 Common - sodium/hydrogen exchanger SACE_5195 17 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 134097712 Common - MFS superfamily, multidrug transport protein SACE_1117 216 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134102603 Nonpathogen - hypothetical protein SACE_6166 4 None None None 134100606 Nonpathogen - hypothetical protein SACE_4071 1 None None None 134101541 Nonpathogen - hypothetical protein SACE_5013 3 None None None 134099256 Nonpathogen - hypothetical protein SACE_2711 1 None None None 134102854 Common - transcriptional regulator, AraC family SACE_6420 114 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 134102907 Common - glycosyl transferase, group 1 SACE_6474 90 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 134101369 Common - cell wall-associated hydrolase SACE_4840 125 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 134096703 Common - transcriptional regulator, ArsR family SACE_0085 34 COG0640 ArsR, Predicted transcriptional regulators Transcription 134103667 Common - probable tartrate symporter, MFS superfamily SACE_7245 130 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 134102246 Common - rhodanese-like protein SACE_5798 141 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 134103242 Nonpathogen - hypothetical protein SACE_6814 1 None None None 134100594 Nonpathogen - hypothetical protein SACE_4059 4 None None None 134102398 Common - precorrin-3B C17-methyltransferase SACE_5951 183 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 134103133 Common - two-component system sensor kinase SACE_6703 25 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 134099908 Nonpathogen - hypothetical protein SACE_3369 1 None None None 134100382 Common pgsA CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase SACE_3847 196 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 134098996 Common - hypothetical protein SACE_2434 5 None None None 134099831 Common - amino acid permease-associated region SACE_3292 18 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 134102240 Common - hypothetical protein SACE_5792 17 None None None 134099414 Common rifM phosphatase homolog SACE_2872 187 COG0546 Gph, Predicted phosphatases General function prediction only 134096921 Common - hypothetical protein SACE_0307 41 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134103674 Nonpathogen - protein of unknown function DUF214 SACE_7252 2 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 134097204 Common - cold-shock DNA-binding domain protein SACE_0594 175 COG1278 CspC, Cold shock proteins Transcription 134098273 Common - hypothetical protein SACE_1690 6 COG3688 COG3688, Predicted RNA-binding protein containing a PIN domain General function prediction only 134101493 Nonpathogen - hypothetical protein SACE_4964 1 None None None 134099534 Common - putative myo-inositol phosphate synthase SACE_2992 26 COG1260 INO1, Myo-inositol-1-phosphate synthase Lipid metabolism 134102733 Common thrC threonine synthase SACE_6297 173 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 134101631 Nonpathogen - hypothetical protein SACE_5119 7 None None None 134099460 Common - hypothetical protein SACE_2918 11 None None None 134098110 Common acpM acyl carrier protein SACE_1524 175 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134101866 Common sodF superoxide dismutase [Fe-Zn] 1 (FeSOD I) SACE_5364 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 134103094 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase SACE_6664 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 134097682 Nonpathogen - hypothetical protein SACE_1086 1 None None None 134102928 Nonpathogen - hypothetical protein SACE_6495 1 None None None 134096844 Common - YbaK/prolyl-tRNA synthetase associated region SACE_0227 33 COG2606 EbsC, Uncharacterized conserved protein Function unknown 134098074 Nonpathogen - hypothetical protein SACE_1488 1 COG3115 ZipA, Cell division protein Cell division and chromosome partitioning 134103720 Common - hypothetical protein SACE_7298 4 None None None 134100832 Common - hypothetical protein SACE_4299 210 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 134097298 Common cvnB1 hypothetical protein SACE_0691 12 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 134102999 Nonpathogen - hypothetical protein SACE_6567 1 None None None 134101179 Common ptlB dimethylallyltranstransferase / geranyltranstransferase / geranylgeranyl pyrophosphate synthetase SACE_4646 238 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 134101287 Common acoB acetoin dehydrogenase, beta subunit SACE_4755 217 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 134098337 Common - hypothetical protein SACE_1755 14 None None None 134100461 Common - 2-oxoglutarate ferredoxin oxidoreductase, beta subunit SACE_3926 122 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 134100973 Common - hypothetical protein SACE_4440 12 None None None 134100496 Common - secreted protein SACE_3961 101 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 134103522 Common phoS2 PstS component of phosphate uptake SACE_7099 117 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 134101074 Common - putative transposase SACE_4541 51 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 134103029 Common - glyoxalase/bleomycin resistance protein/dioxygenase SACE_6598 24 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 134100896 Common - hypothetical protein SACE_4363 20 COG5516 COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding General function prediction only 134100910 Common - oxidoreductase FAD-binding region SACE_4377 240 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 134101477 Nonpathogen - hypothetical protein SACE_4947 1 None None None 134102235 Common - dipeptide ABC transporter, ATP-binding protein SACE_5787 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 134102743 Common - glucan 1,4-alpha-glucosidase SACE_6308 30 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 134103425 Common - peptidase, S8A (subtilisin) subfamily SACE_6999 50 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 134098212 Common dapA dihydrodipicolinate synthase SACE_1629 212 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 134100432 Common sahH S-adenosyl-L-homocysteine hydrolase SACE_3897 177 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 134101424 Common - hydrolase, alpha/beta fold family SACE_4894 27 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134097704 Common smpB SsrA-binding protein SACE_1108 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 134103282 Common rpoB DNA-directed RNA polymerase subunit beta SACE_6854 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 134098466 Common - putative secreted sugar binding protein SACE_1890 105 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 134100052 Common pcaH protocatechuate 3,4-dioxygenase beta chain SACE_3514 53 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 134100939 Nonpathogen - hypothetical protein SACE_4406 1 None None None 134103405 Common - hypothetical protein SACE_6979 9 None None None 134101139 Common gudP MFS transporter, phthalate permease family SACE_4606 198 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 134098888 Common - hypothetical protein SACE_2324 7 None None None 134099325 Common - hypothetical protein SACE_2780 97 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 134098176 Common - kinase SACE_1590 19 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 134103580 Common - putative transcriptional regulator, TetR family SACE_7158 10 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 134101063 Common - hypothetical protein SACE_4530 29 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 134099562 Nonpathogen - PE-PGRS family protein SACE_3020 1 COG4907 COG4907, Predicted membrane protein Function unknown 134103446 Nonpathogen - hypothetical protein SACE_7021 1 None None None 134098000 Common rplU 50S ribosomal protein L21 SACE_1414 215 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 134098440 Nonpathogen - hypothetical protein SACE_1864 1 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 134100944 Nonpathogen - hypothetical protein SACE_4411 1 None None None 134101092 Common - Mn2+ and Fe2+ transporters of the NRAMP family-like protein SACE_4559 60 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 134096856 Nonpathogen - hypothetical protein SACE_0240 1 None None None 134101330 Common - possible purine/cytosine permease SACE_4801 19 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 134102444 Common - cell division FtsK/SpoIIIE SACE_6000 5 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 134099973 Common - purine catabolism PurC-like protein SACE_3434 24 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 134098815 Common - vesicle-fusing ATPase SACE_2246 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 134102044 Nonpathogen - hypothetical protein SACE_5594 1 None None None 134098568 Common rrmA rRNA guanine-N1-methyltransferase SACE_1994 53 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134101580 Common - transcriptional regulator, LacI family SACE_5056 126 COG1609 PurR, Transcriptional regulators Transcription 134102484 Common rnhB ribonuclease HII SACE_6047 221 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 134103534 Common pabC probable amino acid aminotransferase SACE_7111 161 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 134100256 Common - esterase, PHB depolymerase SACE_3720 32 COG3509 LpqC, Poly(3-hydroxybutyrate) depolymerase Secondary metabolites biosynthesis, transport, and catabolism 134102371 Common rbfA ribosome-binding factor A SACE_5924 104 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 134097428 Common - transcriptional regulator, LysR family SACE_0823 193 COG0583 LysR, Transcriptional regulator Transcription 134097498 Nonpathogen - putative antigen 34 kDa family SACE_0900 1 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 134096825 Nonpathogen - hypothetical protein SACE_0208 1 COG1846 MarR, Transcriptional regulators Transcription 134097386 Common - glyoxalase/bleomycin resistance protein/dioxygenase SACE_0780 21 None None None 134096972 Common - hypothetical protein SACE_0358 5 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 134100252 Common - GAF domain protein SACE_3716 47 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 134101764 Common argB acetylglutamate kinase SACE_5260 212 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 134102411 Common chlI putative magnesium-chelatase subunit SACE_5965 70 COG1239 ChlI, Mg-chelatase subunit ChlI Coenzyme metabolism 134098451 Common rocD ornithine--oxo-acid transaminase SACE_1875 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 134103510 Common - dihydrouridine synthase TIM-barrel protein nifR3 SACE_7086 207 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 134102011 Common phoU phosphate transport system regulator SACE_5561 172 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 134101929 Common - putative transposon tn5714 transposase SACE_5430 61 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134100656 Common - probable cysteine desulfurase SACE_4122 228 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 134099457 Common thcA aldehyde dehydrogenase (NAD+) SACE_2915 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 134097163 Common - conserved membrane spanning protein SACE_0552 44 COG2311 COG2311, Predicted membrane protein Function unknown 134101987 Common - acyl-CoA oxidase SACE_5537 27 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134103483 Common - DNA-binding protein SACE_7058 40 None None None 134102346 Common dapA dihydrodipicolinate synthase 1 (DHDPS 1) SACE_5899 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 134102966 Common - peptidase M20D, amidohydrolase SACE_6534 165 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 134097617 Common - hypothetical protein SACE_1021 115 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 134097628 Common - transport integral membrane protein SACE_1032 72 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134097610 Nonpathogen - hypothetical protein SACE_1014 1 None None None 134101395 Common - hypothetical protein SACE_4865 16 COG5502 COG5502, Uncharacterized conserved protein Function unknown 134103773 Common end endonuclease IV SACE_7353 97 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 134097795 Common - thiamineS SACE_1205 44 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 134099755 Common - long-chain acyl-CoA synthetase, putative SACE_3216 148 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134100371 Common - acetyltransferase SACE_3836 26 COG0456 RimI, Acetyltransferases General function prediction only 134100458 Common - exoenzymes regulatory protein AepA precursor SACE_3923 113 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 134102781 Common - phospho-2-dehydro-3-deoxyheptonate aldolase,subtype 1 SACE_6347 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 134097023 Common lsr2 probable iron-regulated LSR2 protein precursor SACE_0410 17 None None None 134097468 Nonpathogen - hypothetical protein SACE_0866 1 None None None 134102291 Nonpathogen - hypothetical protein SACE_5843 1 None None None 134103128 Common - LacI-family transcriptional regulator SACE_6698 129 COG1609 PurR, Transcriptional regulators Transcription 134099201 Common - IS3 family transposase SACE_2654 52 None None None 134099214 Common cysS cysteinyl-tRNA synthetase SACE_2667 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 134103494 Common - oxidoreductase, aldo/keto reductase family SACE_7069 198 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 134103514 Common - phosphate transport system regulator PhoU-related protein SACE_7091 173 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 134102578 Common - NUDIX hydrolase SACE_6141 18 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 134097050 Common - hypothetical protein SACE_0437 6 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 134100480 Common - metabolite transporter, MFS superfamily SACE_3945 139 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 134101061 Common - hypothetical protein SACE_4528 34 COG3535 COG3535, Uncharacterized conserved protein Function unknown 134101099 Common - hypothetical protein SACE_4566 7 None None None 134099393 Common - acyl-CoA dehydrogenase SACE_2850 158 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134099969 Common - oxidoreductase SACE_3430 117 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 134100322 Common fabG1 3-oxoacyl-[acyl-carrier-protein] reductase SACE_3787 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134102167 Nonpathogen - hypothetical protein SACE_5718 1 None None None 134097288 Common - alpha/beta hydrolase fold SACE_0681 154 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134097484 Nonpathogen - hypothetical protein SACE_0886 1 None None None 134100574 Common - alkylhydroperoxidase AhpD core SACE_4039 79 COG2128 COG2128, Uncharacterized conserved protein Function unknown 134098959 Common - hypothetical protein SACE_2396 18 COG5502 COG5502, Uncharacterized conserved protein Function unknown 134101449 Common prnA tryptophan halogenase SACE_4919 16 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 134096869 Common - hypothetical protein SACE_0254 7 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 134097493 Common - hypothetical protein SACE_0895 26 COG4760 COG4760, Predicted membrane protein Function unknown 134102086 Nonpathogen - hypothetical protein SACE_5636 1 None None None 134103365 Common - hypothetical protein SACE_6938 4 None None None 134102307 Common yfaV putative MFS transporter SACE_5859 98 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 134098164 Common - putative fructosamine kinase SACE_1578 69 COG3001 COG3001, Uncharacterized protein conserved in bacteria Function unknown 134099233 Common - putative regulatory protein SACE_2687 31 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 134100540 Common fadE3 putative acyl-CoA dehydrogenase SACE_4005 164 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134100087 Common - DNA ligase (ATP) SACE_3549 66 COG3285 COG3285, Predicted eukaryotic-type DNA primase DNA replication, recombination, and repair 134101263 Common opuD glycine betaine transporter SACE_4731 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 134098303 Common - hypothetical protein SACE_1721 11 COG0456 RimI, Acetyltransferases General function prediction only 134102146 Nonpathogen - hypothetical protein SACE_5697 1 None None None 134097880 Common fadD12 acyl-CoA synthase SACE_1293 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134097400 Common lpsA2 secreted lipase SACE_0794 7 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 134098630 Common - transcriptional regulator, GntR family SACE_2060 132 COG2188 PhnF, Transcriptional regulators Transcription 134103593 Nonpathogen - mucin-associated surface protein SACE_7171 2 COG5373 COG5373, Predicted membrane protein Function unknown 134097441 Common - similar to membrane-bound lytic murein transglycosylase B SACE_0836 19 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 134098103 Common - RNA polymerase sigma factor SACE_1517 34 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 134103648 Common - hypothetical protein SACE_7226 9 None None None 134098068 Common - protein kinase C inhibitor (HIT family) SACE_1482 206 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 134098828 Common - transcriptional regulator-like SACE_2259 36 COG2378 COG2378, Predicted transcriptional regulator Transcription 134097856 Common - S-adenosylmethionine decarboxylase proenzyme SACE_1267 71 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 134097048 Common - protein of unknown function DUF147 SACE_0435 28 COG1623 COG1623, Predicted nucleic-acid-binding protein (contains the HHH domain) General function prediction only 134103719 Common tnp transposase, ISlxx5 SACE_7297 63 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 134101800 Common - hypothetical protein SACE_5297 184 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 134100311 Common - betaine-aldehyde dehydrogenase SACE_3776 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 134100765 Common ramA putative ABC transporter SACE_4232 146 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 134098692 Common ribC riboflavin synthase subunit alpha SACE_2122 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 134101835 Common - putative oxidoreductase SACE_5333 119 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 134097331 Common eryCII TDP-4-keto-6-deoxy-glucose 3,4-isomerase SACE_0725 17 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134102842 Common - IclR-type transcriptional regulator SACE_6408 115 COG1414 IclR, Transcriptional regulator Transcription 134098318 Common recA DNA recombination/repair SACE_1736 244 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 134098979 Common - universal stress protein SACE_2417 18 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 134101742 Common scpB putative segregation and condensation protein B SACE_5238 145 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 134102190 Common - glutamate synthase, NADH/NADPH, small subunit 1 SACE_5741 207 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 134099272 Common - oxidoreductase FAD-binding region SACE_2727 137 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 134099378 Nonpathogen - hypothetical protein SACE_2835 5 None None None 134099362 Common - phthalate 4,5-dioxygenase reductase subunit SACE_2819 115 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 134098586 Common - glyoxalase/bleomycin resistance protein/dioxygenase SACE_2012 41 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 134101275 Nonpathogen - hypothetical protein SACE_4743 1 None None None 134103714 Nonpathogen - hypothetical protein SACE_7292 1 None None None 134098478 Common - response regulator receiver and ANTAR domain protein SACE_1903 16 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 134099265 Nonpathogen - hypothetical protein SACE_2720 1 None None None 134097312 Common - PEP phosphonomutase SACE_0705 60 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 134100318 Common - hypothetical protein SACE_3783 15 None None None 134098182 Common - lipoprotein SACE_1598 139 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 134099208 Common - TetR family transcriptional regulatory protein SACE_2661 28 COG1309 AcrR, Transcriptional regulator Transcription 134102122 Nonpathogen - hypothetical protein SACE_5672 2 None None None 134099788 Common soxA putative sarcosine oxidase alpha subunit SACE_3249 26 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 134101825 Common rstP LacI-family transcriptional regulator SACE_5322 122 COG1609 PurR, Transcriptional regulators Transcription 134101724 Common serA D-3-phosphoglycerate dehydrogenase, putative SACE_5219 230 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 134101971 Nonpathogen - hypothetical protein SACE_5515 1 None None None 134103220 Common - cell division FtsK/SpoIIIE SACE_6792 192 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 134096641 Common - beta-ketoacyl synthase SACE_0023 209 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134100032 Common - enantiomer-selective amidase SACE_3494 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 134097371 Common - possible serine protease, C-terminal SACE_0765 220 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 134103740 Common - NHL repeat containing protein SACE_7318 76 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 134099339 Common - p-hydroxycinnamoyl CoA hydratase/lyase SACE_2794 178 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 134098639 Nonpathogen - hypothetical protein SACE_2069 1 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 134100630 Common - nucleoside-diphosphate sugar epimerase (SulA family) SACE_4096 104 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 134101159 Common - carbohydrate-binding protein SACE_4626 9 None None None 134100103 Common - acyl-CoA dehydrogenase, middle domain SACE_3565 147 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134103227 Common - hypothetical protein SACE_6799 5 None None None 134100170 Common - putative transposase SACE_3632 51 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 134096895 Common - integral membrane protein SACE_0281 16 COG5542 COG5542, Predicted integral membrane protein Function unknown 134097918 Common glbO hemoglobin-like, oxygen carrier SACE_1331 67 COG2346 COG2346, Truncated hemoglobins General function prediction only 134098934 Nonpathogen - Putative transposase SACE_2370 4 None None None 134097654 Common - transcriptional regulator, TetR family SACE_1058 28 COG1309 AcrR, Transcriptional regulator Transcription 134100204 Common - acetyltransferase SACE_3666 61 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 134099367 Nonpathogen - hypothetical protein SACE_2824 1 None None None 134103390 Common ppx1 exopolyphosphatase SACE_6964 179 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 134103322 Common nuoI NADH dehydrogenase subunit I SACE_6894 193 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 134102094 Common - secreted protein SACE_5644 9 COG5276 COG5276, Uncharacterized conserved protein Function unknown 134099446 Common - sugar transporter, MFS superfamily SACE_2904 134 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134101085 Common - binding-protein-dependent transport systems membrane component SACE_4552 194 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 134099431 Common cysE serine O-acetyltransferase SACE_2889 189 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 134100874 Common - methyltransferase SACE_4341 83 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 134101667 Common nanH neuraminidase SACE_5159 24 COG4409 NanH, Neuraminidase (sialidase) Carbohydrate transport and metabolism 134098195 Common - probable exported protease SACE_1611 39 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134100094 Common - probable phthalate 4,5-dioxygenase SACE_3556 117 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 134098367 Common - D-tyrosyl-tRNA(Tyr) deacylase SACE_1787 114 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 134099689 Common - NAD/factor-dependent formaldehyde dehydrogenase SACE_3147 207 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 134101924 Common - putative DNA-binding protein SACE_5425 17 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 134097649 Nonpathogen - hypothetical protein SACE_1053 1 None None None 134097996 Common pnbA,estB para-nitrobenzyl esterase SACE_1410 53 COG2272 PnbA, Carboxylesterase type B Lipid metabolism 134098948 Common - hypothetical protein SACE_2384 27 COG3552 CoxE, Protein containing von Willebrand factor type A (vWA) domain General function prediction only 134103456 Nonpathogen - hypothetical protein SACE_7031 3 None None None 134100361 Common gshA glutamate-cysteine ligase SACE_3826 54 COG3572 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 134096754 Common fahA fumarylacetoacetase hydrolase SACE_0136 50 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 134100190 Common - hypothetical protein SACE_3652 9 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 134098370 Common - HhH-GPD SACE_1790 11 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 134098236 Common - hypothetical protein SACE_1653 19 None None None 134101573 Common - short-chain dehydrogenase/reductase SDR SACE_5049 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134103183 Common - cyclopropane-fatty-acyl-phospholipid synthase SACE_6753 132 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 134097813 Common - glycosyl transferase, family 39 SACE_1223 7 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 134098686 Common - probable integral membrane protein SACE_2116 3 COG5660 COG5660, Predicted integral membrane protein Function unknown 134102931 Common - hypothetical protein SACE_6498 8 COG1865 COG1865, Uncharacterized conserved protein Function unknown 134097575 Common aao D-amino acid oxidase SACE_0979 14 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 134098925 Common - mammalian cell entry SACE_2361 16 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 134102620 Common fadD5 acyl-CoA synthetase SACE_6183 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134099485 Nonpathogen - hypothetical protein SACE_2943 5 COG3801 COG3801, Uncharacterized protein conserved in bacteria Function unknown 134097437 Nonpathogen - hypothetical protein SACE_0832 1 None None None 134103812 Common gidB putative glucose inhibited division protein B SACE_7392 147 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 134100201 Common - transcriptional regulator, XRE family SACE_3663 6 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 134098355 Common galE UDP-glucose 4-epimerase SACE_1774 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 134099717 Common cps2I glycosyl transferase, group 1 family protein,putative SACE_3177 173 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 134096914 Common - transcriptional regulator, XRE family SACE_0300 6 COG2944 COG2944, Predicted transcriptional regulator Transcription 134098786 Common - von Willebrand factor, type A SACE_2216 20 COG4867 COG4867, Uncharacterized protein with a von Willebrand factor type A (vWA) domain General function prediction only 134098363 Nonpathogen - hypothetical protein SACE_1783 1 None None None 134103274 Common draG ADP-ribosylglycohydrolase SACE_6846 23 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 134098498 Nonpathogen - hypothetical protein SACE_1923 1 None None None 134103397 Common - glycosyl transferase SACE_6971 142 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 134102656 Nonpathogen - hypothetical protein SACE_6219 1 None None None 134102828 Common - protein of unknown function DUF59 SACE_6394 15 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 134098242 Common - two-component system sensor kinase SACE_1659 105 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 134098612 Common aspS aspartyl-tRNA synthetase SACE_2041 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 134100353 Common - protein of unknown function DUF81 SACE_3818 19 None None None 134097110 Common - hypothetical protein SACE_0497 50 COG3618 COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 134100887 Common - flavin oxidoreductase/NADH oxidase SACE_4354 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 134102556 Common recG putative ATP-dependent DNA helicase SACE_6119 210 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 134103100 Nonpathogen - hypothetical protein SACE_6670 1 None None None 134103036 Nonpathogen - secreted protein SACE_6606 3 None None None 134101152 Common - molybdopterin dehydrogenase, FAD-binding SACE_4619 65 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 134103244 Nonpathogen - hypothetical protein SACE_6816 1 None None None 134098247 Common - maltose/maltodextrin transport system (permease) SACE_1664 148 COG3833 MalG, ABC-type maltose transport systems, permease component Carbohydrate transport and metabolism 134097277 Nonpathogen - hypothetical protein SACE_0668 1 None None None 134103752 Common - protein kinase/transcriptional regulator, LuxR family SACE_7332 92 COG3903 COG3903, Predicted ATPase General function prediction only 134101132 Common - transcriptional regulator, XRE family SACE_4599 41 COG1396 HipB, Predicted transcriptional regulators Transcription 134096704 Common - hypothetical protein SACE_0086 5 None None None 134102217 Common dctA putative sodium:dicarboxylate symporter SACE_5768 143 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 134098542 Common - 1-aminocyclopropane-1-carboxylate deaminase SACE_1968 59 COG2515 Acd, 1-aminocyclopropane-1-carboxylate deaminase Amino acid transport and metabolism 134101453 Common - hypothetical protein SACE_4923 208 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134099095 Nonpathogen - hypothetical protein SACE_2540 1 None None None 134102634 Common fixA electron transfer flavoprotein, beta subunit SACE_6197 153 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 134102871 Nonpathogen - hypothetical protein SACE_6437 1 None None None 134101801 Common kdgR predicted DNA-binding transcriptional regulator SACE_5298 124 COG1414 IclR, Transcriptional regulator Transcription 134102690 Common - hypothetical protein SACE_6254 7 COG1309 AcrR, Transcriptional regulator Transcription 134100368 Common - CBS domain protein SACE_3833 212 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 134101072 Common iolT sugar transporter SACE_4539 117 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134103637 Common - hypothetical protein SACE_7215 10 None None None 134097521 Common - protein of unknown function DUF255 SACE_0923 105 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 134103745 Common - drug resistance transporter, EmrB/QacA family SACE_7323 153 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 162316923 Common - 3-oxoacyl-(acyl carrier protein) synthase III SACE_5540 213 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 134101116 Common - alpha-ketoglutarate transporter, MFS superfamily SACE_4583 154 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 134101370 Common - mandelate racemase/muconate lactonizing enzyme SACE_4841 103 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 134101873 Common gbsA glycine betaine aldehyde dehydrogenase SACE_5371 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 134098570 Common - probable transcriptional regulator, TetR family SACE_1996 17 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 134102420 Common kdgK 2-keto-3-deoxygluconate kinase SACE_5974 170 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 134101160 Common rpmJ 50S ribosomal protein L36 SACE_4627 38 None None None 134102823 Common tdh L-threonine 3-dehydrogenase SACE_6389 208 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 134096675 Common - monooxygenase, FAD-binding SACE_0057 39 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 134100005 Common - DJ-1/PfpI-family transcriptional regulator SACE_3467 85 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 134102738 Common - hypothetical protein SACE_6302 29 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 134100671 Common - type I PKS modular polyketide synthas SACE_4138 210 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134098408 Common - hypothetical protein SACE_1831 10 None None None 134101551 Nonpathogen - hypothetical protein SACE_5027 1 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 134098002 Common obgE GTPase ObgE SACE_1416 249 COG0536 Obg, Predicted GTPase General function prediction only 134101380 Common - putative transposase SACE_4850a 11 None None None 134103143 Common - DNA-binding regulator SACE_6713 19 COG0789 SoxR, Predicted transcriptional regulators Transcription 134097255 Common acd acyl-CoA dehydrogenase SACE_0645 167 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134099813 Common aglA alpha-glucosidase SACE_3274 18 None None None 134103791 Common - transcriptional regulator, TetR family SACE_7371 38 COG1309 AcrR, Transcriptional regulator Transcription 134099673 Common - AMP-dependent acetyl-coenzyme A synthetase and ligase SACE_3131 220 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 134099452 Common - hypothetical protein SACE_2910 22 COG0477 ProP, Permeases of the major facilitator superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / Inorganic ion transport and metabolism / General function prediction only 134103411 Common - hypothetical protein SACE_6985 14 None None None 134097539 Common rbsA ribose transport ATP-binding protein SACE_0941 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 134099749 Common - xylose isomerase domain protein TIM barrel SACE_3210 8 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 134097258 Common - citrate synthase SACE_0649 194 COG0372 GltA, Citrate synthase Energy production and conversion 134096667 Common - FHA domain containing protein SACE_0049 44 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 134097117 Common - amino acid oxidase flavoprotein ThiO, putative SACE_0506 95 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 134103528 Common - hypothetical protein SACE_7105 9 None None None 134097037 Common - probable ABC transporter, ATP-binding component SACE_0424 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 134097890 Common - probable myosin SACE_1303 8 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 134101558 Common - hypothetical protein SACE_5034 10 None None None 134101310 Common - YD repeat protein SACE_4778 68 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 134099557 Common - non-ribosomal peptide synthetase SACE_3015 209 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134103111 Common uvrD putative ATP-dependent DNA helicase SACE_6681 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 134098229 Common - branched-chain amino acid aminotransferase SACE_1646 206 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 134100681 Common - probable membrane protein SACE_4148 2 None None None 134100029 Nonpathogen - hypothetical protein SACE_3491 1 None None None 134099868 Common bioA2 adenosylmethionine-8-amino-7-oxononanoate transaminase SACE_3329 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 134102427 Common cobQ cobyric acid synthase SACE_5983 153 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 134100175 Nonpathogen - hypothetical protein SACE_3637 1 None None None 134098643 Common - putative integral membrane transport protein SACE_2072 76 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134103747 Common - transcriptional regulator, TetR family SACE_7325 44 COG1309 AcrR, Transcriptional regulator Transcription 134098738 Common ctaA cytochrome oxidase assembly protein SACE_2168 18 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 134100612 Common sidE siderophore-interacting protein SACE_4077 62 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 134098821 Common prcA 20S proteasome alpha-subunit SACE_2252 14 COG0638 PRE1, 20S proteasome, alpha and beta subunits Posttranslational modification, protein turnover, chaperones 134099791 Common - proline racemase SACE_3252 47 COG3938 COG3938, Proline racemase Amino acid transport and metabolism 134101206 Common - MerR-family transcriptional regulator SACE_4674 20 COG0789 SoxR, Predicted transcriptional regulators Transcription 134100558 Common gatA glutamyl-tRNA(Gln) amidotransferase, A subunit SACE_4023 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 134102163 Nonpathogen - hypothetical protein SACE_5714 1 None None None 134100569 Common - transport integral membrane protein SACE_4034 178 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134098773 Common - hypothetical protein SACE_2203 17 None None None 134102546 Common - glycosyl transferase, family 39 SACE_6109 7 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 134098549 Common - two-component system response regulator SACE_1975 93 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 134099945 Common - alcohol dehydrogenase, zinc-binding domain protein SACE_3406 106 COG2130 COG2130, Putative NADP-dependent oxidoreductases General function prediction only 134097033 Common - hypothetical protein SACE_0420 131 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 134098085 Common - probable arsenical resistance operon repressor SACE_1499 176 COG0640 ArsR, Predicted transcriptional regulators Transcription 134099026 Common - universal stress protein family SACE_2464 25 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 134102302 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase SACE_5854 211 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 134100666 Common - ketoacyl-ACP synthase (typeII) SACE_4133 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134102808 Common sti1 protease inhibitor protein SACE_6374 3 None None None 134097121 Common thiD phosphomethylpyrimidine kinase SACE_0510 214 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 134099516 Common iorA isoquinoline 1-oxidoreductase, alpha subunit SACE_2974 119 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 134102470 Common - glyoxalase/bleomycin resistance protein/dioxygenase SACE_6032 43 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 134096944 Nonpathogen - hypothetical protein SACE_0330 1 None None None 134097891 Common - hypothetical protein SACE_1304 51 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 134100132 Nonpathogen - hypothetical protein SACE_3594 1 None None None 134102055 Common - amino acid permease-associated region SACE_5605 167 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 134099638 Common - amidohydrolase 2 SACE_3096 7 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 134103199 Nonpathogen - hypothetical protein SACE_6770 1 None None None 134101431 Common - hypothetical protein SACE_4901 4 None None None 134097307 Common - oxidoreductase, short-chain dehydrogenase/reductase family SACE_0700 30 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 134100181 Common xerC tyrosine recombinase XerC SACE_3643 184 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 134100619 Common - possible epoxide hydrolase SACE_4084 53 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134100736 Common gbsA glycine betaine aldehyde dehydrogenase SACE_4203 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 134097216 Common fabF 3-oxoacyl-[acyl-carrier-protein] synthase II SACE_0606 207 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134100266 Common - hypothetical protein SACE_3731 20 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 134096998 Common mrcB membrane carboxypeptidase, penicillin-binding protein SACE_0385 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 134099611 Common gmhA phosphoheptose isomerase SACE_3069 112 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 134099493 Common clpC putative ATP-dependent Clp protease SACE_2951 100 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 134101978 Nonpathogen - hypothetical protein SACE_5522 2 None None None 134102074 Common uspA1 putative universal stress protein SACE_5624 64 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 134098804 Common - HAD-superfamily hydrolase subfamily IA, variant 3 SACE_2235 189 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 134103538 Nonpathogen amfC aerial mycelium formation SACE_7115 4 None None None 134100217 Common terC tellurium resistance membrane protein SACE_3679 89 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 134097509 Common ligB ATP-dependent DNA ligase SACE_0911 103 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 134101185 Common - protein kinase/transcriptional regulator, LuxR family SACE_4652 108 COG3903 COG3903, Predicted ATPase General function prediction only 134098046 Nonpathogen - hypothetical protein SACE_1460 1 None None None 134099427 Common toxC WD domain protein SACE_2885 43 COG2319 COG2319, FOG: WD40 repeat General function prediction only 134100225 Common fabG 3-oxoacyl-[acyl-carrier-protein] reductase SACE_3687 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134103614 Common - hypothetical protein SACE_7192 10 COG5640 COG5640, Secreted trypsin-like serine protease Posttranslational modification, protein turnover, chaperones 134102432 Nonpathogen - hypothetical protein SACE_5988 1 None None None 134102018 Common - short-chain dehydrogenase/reductase SDR SACE_5568 229 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 134102404 Common nicT2 high-affinity nickel-transport protein SACE_5958 34 COG3376 HoxN, High-affinity nickel permease Inorganic ion transport and metabolism 134102665 Common - sugar ABC transporter, ATP binding protein SACE_6228 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 134099136 Common - oxidoreductase, short chain dehydrogenase/reductase family SACE_2581 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134101042 Common - oxidoreductase alpha (molybdopterin) subunit SACE_4509 176 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 134100539 Common bglC endo-1,4-beta-glucanase; RBL03973 SACE_4004 17 COG2730 BglC, Endoglucanase Carbohydrate transport and metabolism 134099826 Common - transmembrane transport protein SACE_3287 23 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 134097082 Nonpathogen - hypothetical protein SACE_0468 1 None None None 134101211 Common - transcriptional regulator, LysR family SACE_4679 15 COG0583 LysR, Transcriptional regulator Transcription 134103624 Common - integral membrane transport protein SACE_7202 221 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134098864 Common dapE2 hypothetical protein SACE_2296 195 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 134101916 Nonpathogen - hypothetical protein SACE_5415 1 None None None 134103203 Nonpathogen - hypothetical protein SACE_6774 1 None None None 134102958 Common - hypothetical protein SACE_6525 2 COG3011 COG3011, Uncharacterized protein conserved in bacteria Function unknown 134098829 Common - transcriptional regulator-like protein SACE_2260 33 COG2378 COG2378, Predicted transcriptional regulator Transcription 134097783 Common fadD acyl-CoA synthase SACE_1193 170 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134102674 Nonpathogen - hypothetical protein SACE_6237 2 None None None 134103297 Nonpathogen - hypothetical protein SACE_6869 1 None None None 134098673 Common metK methionine adenosyltransferase 1 (AdoMet synthetase) SACE_2103 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 134098972 Common - putative glycine betaine/proline ABC transporter SACE_2410 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 134099032 Common - hypothetical protein SACE_2471 4 None None None 134101548 Common - major facilitator superfamily MFS_1 SACE_5024 56 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134097695 Common - hypothetical protein SACE_1099 26 COG5282 COG5282, Uncharacterized conserved protein Function unknown 134101980 Nonpathogen - hypothetical protein SACE_5524 2 None None None 134098061 Common cysH phosphoadenosine phosphosulfate reductase SACE_1475 161 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 134099723 Common - probable glycerol-3-phosphate cytidyltransferase SACE_3183 102 COG0615 TagD, Cytidylyltransferase Cell envelope biogenesis, outer membrane / Lipid metabolism 134097150 Common - carbon monoxide dehydrogenase subunit G SACE_0539 34 COG3427 COG3427, Uncharacterized conserved protein Function unknown 134101489 Nonpathogen - hypothetical protein SACE_4960 1 None None None 134098009 Common - ATP-dependent DNA helicase, RecQ family SACE_1423 177 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 134099984 Common - putative transcriptional regulator of the TetR family SACE_3446 12 COG1309 AcrR, Transcriptional regulator Transcription 134099314 Nonpathogen - hypothetical protein SACE_2769 1 None None None 134102642 Common - hypothetical protein SACE_6205 22 None None None 134100714 Common - ATP dependent DNA ligase SACE_4181 69 COG3285 COG3285, Predicted eukaryotic-type DNA primase DNA replication, recombination, and repair 134103268 Common rpsG 30S ribosomal protein S7 SACE_6840 238 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 134100923 Nonpathogen - hypothetical protein SACE_4390 1 None None None 134099653 Common dnaK heat shock protein HSP70 SACE_3111 234 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 134098136 Common - hypothetical protein SACE_1550 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 134096660 Common - transposase for IS3508i SACE_0042 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 134099168 Common - non-ribosomal peptide synthetase SACE_2619 216 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134101722 Common dak putative dihydroxyacetone (glycerone) kinase protein SACE_5217 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 134100851 Common - hypothetical protein SACE_4318 7 None None None 134100813 Common - SyrP-like protein SACE_4280 22 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 134100731 Common - putative regulatory protein SACE_4198 117 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 134097138 Common groEL chaperonin GroEL SACE_0527 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 134100478 Common - hypothetical protein SACE_3943 11 None None None 134101197 Common - PadR-like family transcriptional regulator SACE_4665 32 COG1695 COG1695, Predicted transcriptional regulators Transcription 134098150 Common - ATPase SACE_1564 22 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 134101383 Common - putative transcriptional regulator, LysR family SACE_4853 92 COG0583 LysR, Transcriptional regulator Transcription 134102195 Common lgt prolipoprotein diacylglyceryl transferase SACE_5746 184 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 134097935 Common - putative lipoprotein SACE_1348 9 COG2045 COG2045, Phosphosulfolactate phosphohydrolase and related enzymes Coenzyme metabolism / General function prediction only 134102782 Common blaA2 beta-lactamase SACE_6348 132 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 134099223 Common - putative aminoglycoside phosphotransferase SACE_2677 9 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 134101758 Common tyrS,tyr tyrosyl-tRNA synthetase SACE_5254 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 134102975 Common - similar to multisubunit Na+/H+ antiporter MnhC subunit SACE_6543 74 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 134101192 Common iolE phosphate isomerases/epimerase SACE_4659 60 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 134101296 Common - putative ribose 5-phosphate isomerase SACE_4764 116 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 134099243 Common - putative ABC-type Fe3+-siderophores transport system SACE_2697 49 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 134103549 Common - hypothetical protein SACE_7127 18 None None None 134098311 Common - putative transcriptional regulator, TetR family SACE_1729 16 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 134101884 Common fadE16 acyl-CoA dehydrogenase SACE_5382 143 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134097530 Common yumC thioredoxin reductase SACE_0932 210 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 134103418 Nonpathogen - hypothetical protein SACE_6992 1 None None None 134098653 Common carA carbamoyl-phosphate synthase small subunit SACE_2082 232 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 134099710 Common - hypothetical protein SACE_3170 6 None None None 134097157 Nonpathogen - hypothetical protein SACE_0546 1 None None None 134099630 Common - two-component system sensor kinase SACE_3088 60 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 134098447 Common ribD 5-amino-6-(5-phosphoribosylamino)uracil reductase SACE_1871 89 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 134102712 Common - LysR-family transcriptional regulator SACE_6276 183 COG0583 LysR, Transcriptional regulator Transcription 134100425 Common mmuM homocysteine methyltransferase SACE_3890 161 COG2040 MHT1, Homocysteine/selenocysteine methylase (S-methylmethionine-dependent) Amino acid transport and metabolism 134103179 Common - serine/threonine protein kinase SACE_6749 137 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 134099116 Common - IS1647-like transposase SACE_2561 39 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134102352 Common - protein of unknown function DUF1006 SACE_5905 61 COG3214 COG3214, Uncharacterized protein conserved in bacteria Function unknown 134102508 Common smc chromosome segregation ATPase SACE_6071 189 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 134100288 Nonpathogen - hypothetical protein SACE_3753 1 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 134102517 Common - transcriptional regulator, MarR family SACE_6080 152 COG1733 COG1733, Predicted transcriptional regulators Transcription 134099004 Common - universal stress protein SACE_2442 22 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 134097587 Common - dipeptide transport system permease protein SACE_0991 218 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 134100880 Common - putative sodium:solute symporter SACE_4347 169 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 134101182 Common ubiH 2-octaprenyl-6-methoxyphenol 4-monoxygenase SACE_4649 23 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 134096876 Common - oligopeptide ABC transporter ATP-binding protein SACE_0261 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 134100262 Common - acetyltransferase, GNAT family SACE_3727 19 COG0456 RimI, Acetyltransferases General function prediction only 134096748 Common - ferritin family protein SACE_0130 96 COG1528 Ftn, Ferritin-like protein Inorganic ion transport and metabolism 134098329 Nonpathogen - hypothetical protein SACE_1747 1 None None None 134101629 Nonpathogen - putative transposase SACE_5117 2 None None None 134103343 Common menE O-succinylbenzoic acid--CoA ligase SACE_6916 197 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134098286 Common pfkA 6-phosphofructokinase SACE_1704 161 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 134102067 Common - aminomethyltransferase SACE_5617 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 134101438 Common - cyclic nucleotide-binding domain (cNMP-BD) protein SACE_4908 30 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 134100583 Common - hypothetical protein SACE_4048 5 None None None 134096716 Common glxK glycerate kinase SACE_0098 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 134099619 Common hypF1 [NiFe] hydrogenase maturation protein HypF SACE_3077 116 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 134098507 Common - formamidase SACE_1932 50 COG2421 COG2421, Predicted acetamidase/formamidase Energy production and conversion 134097906 Common - NUDIX hydrolase SACE_1319 14 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 134099277 Common - probable transcriptional regulator SACE_2732 65 COG1309 AcrR, Transcriptional regulator Transcription 134100122 Common - putative polyketide oxygenase/hydroxylase SACE_3584 103 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 134102103 Common - hypothetical protein SACE_5653 14 None None None 134099968 Common cyp28 cytochrome P450 hydroxylase SACE_3429 82 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134099601 Common hupD1 hydrogenase maturation protein HupD SACE_3059 23 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 134101633 Common - IS3 family transposase SACE_5121 52 None None None 134101013 Nonpathogen - hypothetical protein SACE_4480 1 None None None 134101156 Common - carboxypeptidase G2 precursor SACE_4623 109 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 134099113 Common - probable multidrug resistance transporter, MFS superfamily SACE_2558 8 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134098048 Common - hypothetical protein SACE_1462 7 COG2732 COG2732, Barstar, RNAse (barnase) inhibitor Transcription 134098840 Common ptsA putative phosphoenolpyruvate-protein phosphotransferase enzyme I SACE_2271 177 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 134101967 Nonpathogen - hypothetical protein SACE_5511 1 None None None 134097128 Nonpathogen - hypothetical protein SACE_0517 1 None None None 134099901 Common - short chain dehydrogenase SACE_3362 202 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 134102327 Common - competence-inducible (CinA-like) protein SACE_5880 190 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 134100403 Common - enoyl-CoA hydratase/isomerase SACE_3868 171 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 134098902 Common - hypothetical protein SACE_2338 20 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 134098419 Common adhA NADP-dependent alcohol dehydrogenase SACE_1843 195 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 134096915 Nonpathogen - hypothetical protein SACE_0301 2 None None None 134102771 Common cvnB1 hypothetical protein SACE_6337 16 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 134099648 Nonpathogen - hypothetical protein SACE_3106 1 None None None 134099975 Common - hypothetical protein SACE_3436 32 COG2030 MaoC, Acyl dehydratase Lipid metabolism 134098313 Common - hypothetical protein SACE_1731 15 None None None 134101597 Common embC putative arabinosyl transferase SACE_5074 5 None None None 134101356 Common - oxidoreductase SACE_4827 44 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 134103068 Nonpathogen - hypothetical protein SACE_6638 1 None None None 134100275 Common - transcriptional regulator, GntR family SACE_3740 129 COG1802 GntR, Transcriptional regulators Transcription 134101343 Common - transposase SACE_4814 64 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134098862 Nonpathogen - hypothetical protein SACE_2294 2 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 134103403 Nonpathogen - hypothetical protein SACE_6977 4 None None None 134099100 Common - WD-40 repeat protein SACE_2545 69 COG2319 COG2319, FOG: WD40 repeat General function prediction only 134100847 Common - metal-dependent hydrolase SACE_4314 67 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 134099927 Common - Asp/Glu racemase SACE_3388 42 COG4126 COG4126, Hydantoin racemase Amino acid transport and metabolism 134101327 Common - hypothetical protein SACE_4797 3 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 134096713 Common rkpK UDP-glucose 6-dehydrogenase protein SACE_0095 205 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 134101504 Nonpathogen - hypothetical protein SACE_4976 1 None None None 134100149 Nonpathogen - hypothetical protein SACE_3611 1 COG5373 COG5373, Predicted membrane protein Function unknown 134102026 Nonpathogen - hypothetical protein SACE_5576 2 COG5039 COG5039, Exopolysaccharide biosynthesis protein Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 134101740 Common - sodium/hydrogen exchanger SACE_5236 125 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 134099782 Common fadE12 acyl-CoA dehydrogenase SACE_3243 160 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134098138 Common - allophanate hydrolase subunit 2 SACE_1552 115 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 134096885 Nonpathogen - hypothetical protein SACE_0270 1 None None None 134098534 Common - hypothetical protein SACE_1960 14 None None None 134098802 Common - hypothetical protein SACE_2233 23 COG2047 COG2047, Uncharacterized protein (ATP-grasp superfamily) General function prediction only 134101581 Common - mandelate racemase/starvation sensing protein SACE_5057 101 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 134097514 Common - hypothetical protein SACE_0916 12 None None None 134099051 Common - integral membrane protein SACE_2494 14 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 134099042 Common - hypothetical protein SACE_2482 33 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 134100770 Common - probable acetyl/propionyl-CoA carboxylase alpha subunit SACE_4237 234 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 134098253 Common glsA glutaminase SACE_1670 72 COG2066 GlsA, Glutaminase Amino acid transport and metabolism 134102866 Common - hypothetical protein SACE_6432 36 COG3571 COG3571, Predicted hydrolase of the alpha/beta-hydrolase fold General function prediction only 134101360 Common lacG ABC transporter sugar permease SACE_4831 141 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 134097102 Common - transcriptional regulator, SARP family SACE_0488 37 COG3629 DnrI, DNA-binding transcriptional activator of the SARP family Signal transduction mechanisms 134098832 Common - sec-independent protein translocase TatC SACE_2263 204 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 134098766 Common - putative ABC transporter ATP-binding protein SACE_2196 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 134100489 Common bkdC2 branched-chain alpha-keto acid dehydrogenase subunit E2 SACE_3954 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 134099109 Common - possible transcriptional regulator SACE_2554 13 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 134098116 Common - nicotinamide mononucleotide transporter SACE_1530 48 COG3201 PnuC, Nicotinamide mononucleotide transporter Coenzyme metabolism 134102457 Common - transmembrane transport protein SACE_6019 24 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 134102225 Common hisB imidazoleglycerol-phosphate dehydratase SACE_5776 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 134103609 Common - tRNA/rRNA methyltransferase (SpoU) SACE_7187 112 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 134098334 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase SACE_1752 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 134096743 Common cyp20 putative cytochrome P450 SACE_0125 66 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134100759 Common serA D-3-phosphoglycerate dehydrogenase SACE_4226 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 134098510 Common gcl glyoxylate carboligase SACE_1935 221 COG3960 COG3960, Glyoxylate carboligase General function prediction only 134102468 Common - iron (metal) dependent repressor, DtxR family SACE_6030 113 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 134103386 Common fadD9 acyl-CoA synthetase SACE_6960 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134101902 Common - hypothetical protein SACE_5401 2 None None None 134098122 Common - hypothetical protein SACE_1536 17 COG1359 COG1359, Uncharacterized conserved protein Function unknown 134103808 Common avtA valine-pyruvate aminotransferase SACE_7388 228 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 134103568 Common - NAD-dependent epimerase/dehydratase SACE_7146 22 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 134101027 Common soxB sarcosine oxidase beta subunit SACE_4494 141 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 134103090 Common dnaE2 error-prone DNA polymerase SACE_6660 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 134100304 Common - decarboxylase SACE_3769 39 COG3473 COG3473, Maleate cis-trans isomerase Secondary metabolites biosynthesis, transport, and catabolism 134099705 Common - possible hydrolase SACE_3165 12 None None None 134101622 Common - transposase SACE_5106 54 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 134098930 Nonpathogen - hypothetical protein SACE_2366 1 COG4767 VanZ, Glycopeptide antibiotics resistance protein Defense mechanisms 134100872 Common acnA,acn aconitate hydratase 1 SACE_4339 222 COG1048 AcnA, Aconitase A Energy production and conversion 134102021 Common - glycosyl transferase, group 1 SACE_5571 213 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 134100644 Common - putative SARP family pathway specific transcriptional activator SACE_4110 20 COG3629 DnrI, DNA-binding transcriptional activator of the SARP family Signal transduction mechanisms 134099764 Nonpathogen - hypothetical protein SACE_3225 1 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 134097019 Common panC pantoate--beta-alanine ligase SACE_0406 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 134099312 Common - TPR domain protein SACE_2767 26 None None None 134102530 Common gde,yknA guanine deaminase SACE_6093 98 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 134096839 Nonpathogen - hypothetical protein SACE_0222 1 COG2391 COG2391, Predicted transporter component General function prediction only 134097393 Common - putative two-component system response regulator SACE_0787 209 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134102761 Common - putative transporter SACE_6326 29 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134102769 Common - protein of unknown function DUF485 SACE_6334 30 COG3162 COG3162, Predicted membrane protein Function unknown 134103430 Common - ABC transporter, ATP-binding component SACE_7004 242 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 134097329 Common eryAII EryAII Erythromycin polyketide synthase modules 3 and 4 SACE_0723 216 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134101125 Common msmE ABC transporter sugar-binding protein SACE_4592 64 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 134102218 Common - DGPFAETKE family protein SACE_5769 37 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 134101143 Common - hypothetical protein SACE_4610 9 None None None 134103781 Common - possible conserved integral membrane protein SACE_7361 12 COG5650 COG5650, Predicted integral membrane protein Function unknown 134098284 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase SACE_1702 170 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 134097743 Common cvnC9 hypothetical protein SACE_1151 8 None None None 134099303 Common - acyl-CoA dehydrogenase-like SACE_2758 134 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134101249 Common - methyltransferase SACE_4717 29 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134097592 Nonpathogen - hypothetical protein SACE_0996 5 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 134103662 Common - hypothetical protein SACE_7240 7 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 134102463 Common tagA1 probable DNA-3-methyladenine glycosylase I protein SACE_6025 131 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 134103437 Nonpathogen - hypothetical protein SACE_7012 1 None None None 134101032 Common folP dihydropteroate synthase SACE_4499 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 134096983 Nonpathogen - hypothetical protein SACE_0370 1 None None None 134099402 Nonpathogen - hypothetical protein SACE_2860 1 None None None 134099546 Nonpathogen - hypothetical protein SACE_3004 2 None None None 134097960 Common penA,blaA beta-lactamase precursor SACE_1374 48 COG2367 PenP, Beta-lactamase class A Defense mechanisms 134100692 Common - sugar ABC transporter, ATP-binding protein SACE_4159 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 134100507 Common - AraC-family transcriptional regulator SACE_3972 90 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 134097015 Common - hypothetical protein SACE_0402 4 None None None 134099296 Common - hypothetical protein SACE_2751 115 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 134101079 Common - secreted protein SACE_4546 48 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 134102354 Common - hypothetical protein SACE_5907 2 COG1238 COG1238, Predicted membrane protein Function unknown 134100599 Common - hypothetical protein SACE_4064 4 COG2267 PldB, Lysophospholipase Lipid metabolism 134098438 Nonpathogen - hypothetical protein SACE_1862 1 None None None 134099906 Common - RNA polymerase, sigma-24 subunit, ECF subfamily SACE_3367 133 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 134100801 Common - AraC-family transcriptional regulator SACE_4268 158 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 134099938 Nonpathogen - Acetyl-CoA carboxylase, probable epsilon subunit SACE_3399 1 None None None 134097670 Common - uroporphyrinogen-III synthetase SACE_1074 20 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 134100975 Common - probable hydroxyacylglutathione hydrolase SACE_4442 216 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 134103686 Nonpathogen - hypothetical protein SACE_7264 1 None None None 134099384 Common - IS1647-like transposase SACE_2841 27 None None None 134097310 Nonpathogen - putative carboxypeptidase SACE_0703 2 None None None 134103360 Common ccsX thiol-disulfide isomerase/thioredoxin SACE_6933 142 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 134100114 Common - integral membrane protein MviN SACE_3576 178 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 134100587 Common - transport-protein, putative permease for cytosine/purines SACE_4052 5 None None None 134096696 Common - putative ABC transporter ATP-binding protein SACE_0078 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 134098291 Common - possible membrane protein SACE_1709 14 None None None 134097527 Common xylB xylulose kinase SACE_0929 133 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 134103118 Nonpathogen - hypothetical protein SACE_6688 1 None None None 134103341 Common menB naphthoate synthase SACE_6914 176 COG0447 MenB, Dihydroxynaphthoic acid synthase Coenzyme metabolism 134098771 Common - protein of unknown function DUF1470 SACE_2201 11 COG5516 COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding General function prediction only 134103013 Common sdhC putative succinate dehydrogenase membrane subunit SACE_6582 15 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 134098810 Common - hypothetical protein SACE_2241 17 None None None 134102997 Common - Betaine-aldehyde dehydrogenase SACE_6565 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 134100069 Common cysN sulfate adenylyltransferase subunit 1 / adenylylsulfate kinase SACE_3531 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 134099239 Common - non-ribosomal peptide synthase SACE_2693 209 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134097320 Common eryBVII dTDP-4-deoxyglucose 3,5-epimerase SACE_0714 163 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 134101732 Common - aldo/keto reductase SACE_5228 191 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 134099940 Common - hypothetical protein SACE_3401 2 None None None 134103680 Common - UspA domain protein SACE_7258 60 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 134102204 Common hisI phosphoribosyl-AMP cyclohydrolase SACE_5755 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 134102540 Common - protein of unknown function DUF574 SACE_6103 14 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 134102778 Common yhjB sodium:solute symporter SACE_6344 130 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 134100152 Common - hypothetical protein SACE_3614 10 COG4789 EscV, Type III secretory pathway, component EscV Intracellular trafficking and secretion 134096826 Common - transcriptional regulator, MarR family SACE_0209 22 COG1846 MarR, Transcriptional regulators Transcription 134097091 Common - hypothetical protein SACE_0477 5 None None None 134099134 Common - hypothetical protein SACE_2579 13 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 134101417 Common - diguanylate cyclase/phosphodiesterase SACE_4887 147 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 134102816 Common - ABC transporter, ATP-binding component SACE_6382 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 134100363 Common - putative amino acid decarboxylase,pyridoxal-dependent protein SACE_3828 102 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 134102117 Common - AsnC-family transcriptional regulator SACE_5667 132 COG1522 Lrp, Transcriptional regulators Transcription 134102877 Common - S30AE family protein SACE_6443 65 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 134101592 Common racX aspartate racemase SACE_5069 80 COG1794 RacX, Aspartate racemase Cell envelope biogenesis, outer membrane 134100479 Common hmgA homogentisate 1,2-dioxygenase SACE_3944 33 COG3508 HmgA, Homogentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 134102057 Common - Na+/H+ antiporter SACE_5607 71 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 134101176 Common - monooxygenase, FAD-binding protein SACE_4643 149 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 134102271 Common rlu ribosomal large subunit pseudouridine synthase SACE_5823 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 134096693 Nonpathogen - hypothetical protein SACE_0075 1 None None None 134099330 Common lao2 L-amino-acid oxidase SACE_2785 37 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 134097859 Common - hypothetical protein SACE_1270 2 None None None 134102005 Common - integral membrane protein SACE_5555 10 None None None 134098722 Common - hypothetical protein SACE_2152 9 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 134103725 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase SACE_7303 232 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134100859 Nonpathogen ispH 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase, 4Fe-4S protein (partial match) SACE_4326 4 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 134098791 Common - nitroreductase SACE_2222 59 COG0778 NfnB, Nitroreductase Energy production and conversion 134098041 Nonpathogen - hypothetical protein SACE_1455 4 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 134098513 Common - alkylhydroperoxidase AhpD SACE_1938 72 COG2128 COG2128, Uncharacterized conserved protein Function unknown 134101532 Nonpathogen - hypothetical protein SACE_5004 1 None None None 134098590 Common ansP,yncF L-asparagine permease SACE_2016 148 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 134100292 Common - multidrug resistance transporter, MFS superfamily SACE_3757 150 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134101333 Common - MFS transporter protein SACE_4804 177 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134097924 Common - hypothetical protein SACE_1337 8 None None None 134102597 Common - hypothetical protein SACE_6160 6 COG3115 ZipA, Cell division protein Cell division and chromosome partitioning 134102223 Common - hypothetical protein SACE_5774 7 None None None 134103226 Common - hypothetical protein SACE_6798 4 None None None 134100472 Common - mandelate racemase/muconate lactonizing enzyme SACE_3937 85 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 134102727 Common - putative methyltransferase SACE_6291 193 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 134100577 Common - SimX4 homolog SACE_4042 14 COG1409 Icc, Predicted phosphohydrolases General function prediction only 134098933 Common - alpha/beta hydrolase fold SACE_2369 167 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134099198 Common - hypothetical protein SACE_2651 19 COG4877 COG4877, Uncharacterized protein conserved in bacteria Function unknown 134099283 Common - alcohol dehydrogenase GroES-like protein SACE_2738 205 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 134101680 Common - alcohol dehydrogenase GroES domain protein SACE_5172 190 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 134096775 Common serS seryl-tRNA synthetase SACE_0158 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 134099853 Common - putative surface layer protein SACE_3314 236 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 134103555 Common aprE extracellular alkaline serine protease SACE_7133 102 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 134101539 Common - hypothetical protein SACE_5011 8 None None None 134102332 Common - putative TetR family transcriptional regulator SACE_5885 70 COG1309 AcrR, Transcriptional regulator Transcription 134101871 Common - cellulose-binding protein SACE_5369 8 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 134101469 Common idnD putative zinc-binding alcohol dehydrogenase SACE_4939 142 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 134098963 Common - hypothetical protein SACE_2401 39 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 134096806 Common - two-component system sensor kinase SACE_0189 186 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 134099438 Common - carboxylesterase, type B SACE_2896 53 COG2272 PnbA, Carboxylesterase type B Lipid metabolism 134097293 Common - transposase for IS3518 SACE_0686 143 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 134101947 Common - two component transcriptional regulator, LuxR family SACE_5449 92 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134103005 Common add adenosine deaminase SACE_6573 102 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 134099522 Common iolG myo-inositol 2-dehydrogenase SACE_2980 86 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 134101638 Common pglZ bacteriophage (phiC31) resistance gene PglZ SACE_5128 9 None None None 134099721 Common - hypothetical protein SACE_3181 8 None None None 134097007 Common - cell cycle protein MesJ SACE_0394 63 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 134100623 Common - putative two-component system sensor kinase SACE_4088 192 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 134097975 Common yvbU similar to transcriptional regulator (LysR family) SACE_1389 165 COG0583 LysR, Transcriptional regulator Transcription 134102795 Nonpathogen - hypothetical protein SACE_6361 1 None None None 134101323 Common - sulfatase SACE_4791 70 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 134103278 Common - transcriptional regulator, GntR family with aminotransferase activity SACE_6850 172 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 134100372 Common - cobalt ABC transporter ATP binding protein SACE_3837 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 134101604 Nonpathogen - hypothetical protein SACE_5083 1 COG0582 XerC, Integrase DNA replication, recombination, and repair 134096805 Common ohrR transcriptional regulator, MarR-family SACE_0188 109 COG1846 MarR, Transcriptional regulators Transcription 134099694 Common - acyl-CoA synthetase SACE_3153 221 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134100993 Nonpathogen - lyase SACE_4460 3 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 134100511 Common - cyclic nucleotide-binding domain protein SACE_3976 31 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 134097190 Nonpathogen - hypothetical protein SACE_0580 4 None None None 134098778 Nonpathogen - hypothetical protein SACE_2208 1 None None None 134098459 Common - binding protein/LacI transcriptional regulator SACE_1883 103 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 134101818 Common - mycothiol-dependent maleylpyruvate isomerase SACE_5315 11 None None None 134101149 Nonpathogen mauE putative methylamine utilization protein SACE_4616 1 None None None 134097608 Common - CHAD domain containing protein SACE_1012 55 COG5607 COG5607, Uncharacterized conserved protein Function unknown 134100898 Common - metallophosphoesterase SACE_4365 24 COG2129 COG2129, Predicted phosphoesterases, related to the Icc protein General function prediction only 134101240 Nonpathogen tetV drug:proton antiporter SACE_4708 3 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 134102211 Common - transketolase B subunit SACE_5762 165 COG3958 COG3958, Transketolase, C-terminal subunit Carbohydrate transport and metabolism 134097871 Common bglSf beta-glucosidase protein SACE_1284 106 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 134101294 Common - hypothetical protein SACE_4762 5 None None None 134100524 Common - enoyl-CoA hydratase/carnithine racemase SACE_3989 179 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 134097519 Common - hypothetical protein SACE_0921 7 None None None 134099465 Common ybiU hypothetical protein SACE_2923 11 None None None 134100413 Common - amino acid permease-associated region SACE_3878 108 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 134098424 Common yfbT predicted hydrolase or phosphatase SACE_1848 99 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 134097698 Common - hypothetical protein SACE_1102 48 COG1615 COG1615, Uncharacterized conserved protein Function unknown 134102527 Nonpathogen - hypothetical protein SACE_6090 1 None None None 134100684 Common - short-chain dehydrogenase/reductase SDR SACE_4151 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134100504 Common - betaine-aldehyde dehydrogenase SACE_3969 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 134100760 Common - uncharacterised conserved protein UCP033563 SACE_4227 40 COG4198 COG4198, Uncharacterized conserved protein Function unknown 134098809 Common - glyoxalase/bleomycin resistance protein/dioxygenase SACE_2240 35 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 134103311 Common rfbA glucose-1-phosphate thymidylyltransferase SACE_6883 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 134096636 Common - amine oxidase, flavin-containing SACE_0018 67 COG2907 COG2907, Predicted NAD/FAD-binding protein General function prediction only 134097660 Common - possible flavin binding monooxygenase SACE_1064 4 None None None 134100818 Common - AMP-dependent synthetase and ligase SACE_4285 206 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134102683 Common - phosphoenolpyruvate-protein phosphotransferase SACE_6246 100 COG3412 COG3412, Uncharacterized protein conserved in bacteria Function unknown 134103584 Common ltaE low-specificity L-threonine aldolase SACE_7162 79 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 134097549 Common - protein of unknown function DUF195 SACE_0951 86 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 134100934 Common citN citrate transporter, citM family SACE_4401 31 COG2851 CitM, H+/citrate symporter Energy production and conversion 134097064 Common - ABC-type transporter, permease component SACE_0451 26 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 134100119 Common - TetR-family transcriptional regulator SACE_3581 30 COG1309 AcrR, Transcriptional regulator Transcription 134101313 Common - hydrolase SACE_4781 90 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 134099310 Common alsR transcriptional regulator (LysR family) SACE_2765 189 COG0583 LysR, Transcriptional regulator Transcription 134102832 Common - putative RNA polymerase, sigma-24 subunit, ECF subfamily SACE_6398 43 COG4941 COG4941, Predicted RNA polymerase sigma factor containing a TPR repeat domain Transcription 134103285 Common - hypothetical protein SACE_6857 4 None None None 134101034 Common sdaA L-serine dehydratase SACE_4501 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 134101672 Common sixA phosphohistidine phosphatase SACE_5164 84 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 134100930 Common - integral membrane protein SACE_4397 7 COG1289 COG1289, Predicted membrane protein Function unknown 134101355 Common - oxidoreductase domain protein SACE_4826 4 None None None 134099624 Common - probable secreted protease SACE_3082 14 None None None 134099425 Common - possible hydride transferase SACE_2883 91 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 134097234 Common mocA oxidoreductase, aldo/keto reductase family SACE_0624 193 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 134102501 Common - transcriptional regulator, GntR family SACE_6064 66 COG2186 FadR, Transcriptional regulators Transcription 134101335 Nonpathogen - hypothetical protein SACE_4806 1 None None None 134099024 Common - hypothetical protein SACE_2462 12 None None None 134096951 Common acsA acetyl-CoA synthetase SACE_0337 216 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 134103256 Common rpmC 50S ribosomal protein L29 SACE_6828 63 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 134101000 Common yagS putative oxidoreductase, FAD-binding domain SACE_4467 91 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 134102416 Common - putative LysR-family transcriptional regulator SACE_5970 152 COG0583 LysR, Transcriptional regulator Transcription 134097556 Nonpathogen - hypothetical protein SACE_0959 1 None None None 134101682 Common iroB putative glycosyl transferase, related to UDP-glucuronosyltransferase SACE_5174 40 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 134098341 Common - transposase SACE_1759 57 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 134101704 Common - amino acid permease-associated region SACE_5198 192 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 134101997 Common - CmpX protein SACE_5547 31 None None None 134103084 Common - hypothetical protein SACE_6654 11 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 134100840 Common - putative transport integral membrane protein SACE_4307 96 COG0679 COG0679, Predicted permeases General function prediction only 134100865 Common - amidinotransferase family protein SACE_4332 29 COG1834 COG1834, N-Dimethylarginine dimethylaminohydrolase Amino acid transport and metabolism 134100533 Common gltB putative glutamate synthase(NADPH) large subunit SACE_3998 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 134103477 Common - methionine synthase, vitamin-B12 independent SACE_7052 81 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 134098607 Common - hypothetical protein SACE_2033 3 None None None 134097260 Common cypA cytochrome P450-like enzyme SACE_0651 87 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134097232 Common fecC putative ABC transporter ATP-binding protein SACE_0622 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 134103131 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein SACE_6701 241 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 134098430 Nonpathogen - hypothetical protein SACE_1854 1 None None None 134097046 Common - plant-type carbonic anhydrase SACE_0433 42 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 134097771 Common - short chain dehydrogenase SACE_1181 236 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 134098131 Nonpathogen - putative regulator SACE_1545 3 None None None 134099554 Common - hypothetical protein SACE_3012 26 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 134100228 Nonpathogen - hypothetical protein SACE_3690 3 None None None 134102973 Common - cation antiporter SACE_6541 19 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 134098743 Common - probable transcriptional regulator SACE_2173 49 COG2345 COG2345, Predicted transcriptional regulator Transcription 134101232 Common - hypothetical protein SACE_4700 73 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 134099254 Nonpathogen - hypothetical protein SACE_2709 1 None None None 134103788 Common ptsA putative phosphoenolpyruvate-protein phosphotransferase enzyme I SACE_7368 232 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 134100246 Common aprA putative alkaline serine protease SACE_3710 111 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 134097994 Common - AraC family transcriptional regulator SACE_1408 15 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 134103470 Common - transcriptional regulator, MarR family SACE_7045 124 COG1846 MarR, Transcriptional regulators Transcription 134100608 Common - indolepyruvate ferredoxin oxidoreductase SACE_4073 94 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 134097684 Nonpathogen - hypothetical protein SACE_1088 1 None None None 134097107 Common gcvH glycine cleavage system H protein SACE_0494 188 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 134099143 Common - transposase, IS4 SACE_2588 35 COG5659 COG5659, FOG: Transposase DNA replication, recombination, and repair 134102613 Common - acetyltransferase SACE_6176 52 COG3153 COG3153, Predicted acetyltransferase General function prediction only 134103578 Common - ABC transporter, ATP-binding/permease protein SACE_7156 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 134103121 Common - putative serine/threonine protein kinase SACE_6691 144 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 134103308 Nonpathogen - hypothetical protein SACE_6880 1 None None None 134097754 Common - carbon monoxide dehydrogenase large subunit SACE_1162 106 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 134102748 Nonpathogen - hypothetical protein SACE_6313 1 None None None 134103168 Nonpathogen - hypothetical protein SACE_6738 1 None None None 134098039 Nonpathogen - hypothetical protein SACE_1453 1 COG5373 COG5373, Predicted membrane protein Function unknown 134101794 Common dhaK dihydroxyacetone kinase, N-terminal domain SACE_5291 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 134103571 Common - hypothetical protein SACE_7149 5 COG3233 COG3233, Predicted deacetylase General function prediction only 134099513 Common - hypothetical protein SACE_2971 8 None None None 134100749 Common - putative TetR-family transcriptional regulator SACE_4216 5 COG1309 AcrR, Transcriptional regulator Transcription 134102493 Common - amidohydrolase SACE_6056 79 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 134103070 Common - TetR-family transcriptional regulator SACE_6640 32 COG1309 AcrR, Transcriptional regulator Transcription 134098097 Common - hypothetical protein SACE_1511 2 None None None 134102852 Nonpathogen - hypothetical protein SACE_6418 2 COG2932 COG2932, Predicted transcriptional regulator Transcription 134103240 Common adk adenylate kinase SACE_6812 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 134101102 Nonpathogen - hypothetical protein SACE_4569 3 None None None 134102940 Common - Maf-like protein SACE_6507 164 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 134103117 Common - LmbE family protein SACE_6687 59 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 134101787 Common staP membrane protein SACE_5284 8 COG3021 COG3021, Uncharacterized protein conserved in bacteria Function unknown 134097340 Common eryCI Erythromycin biosynthesis transaminase EryCI SACE_0734 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 134100144 Common - class II aldolase/adducin (partial match) SACE_3606 32 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 134096977 Common nagA beta-N-acetylglucosaminidase (putative secreted protein) SACE_0363 184 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 134102124 Common - pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase SACE_5674 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 134102392 Common cobM precorrin-4 C11-methyltransferase SACE_5945 202 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 134099063 Common - Na+/H+ antiporter NhaA SACE_2506 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 134100060 Nonpathogen - hypothetical protein SACE_3522 1 None None None 134102364 Nonpathogen - hypothetical protein SACE_5917 2 None None None 134097319 Common eryK cytochrome P450 Erythromycin B/D C-12 hydroxylase SACE_0713 86 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134098876 Nonpathogen - hypothetical protein SACE_2311 2 None None None 134100597 Common msuD luciferase-like monooxygenase SACE_4062 85 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 134102049 Nonpathogen - conserved hypothetical protein present in several antibiotic biosynthetic clusters SACE_5599 2 None None None 134098817 Common - possible NUDIX hydrolase SACE_2248 28 COG1443 Idi, Isopentenyldiphosphate isomerase Lipid metabolism 134101566 Common - iron ABC transporter substrate-binding protein SACE_5042 72 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 134097570 Common gvpA1 gas vesicle synthesis-like protein SACE_0974 22 None None None 134102376 Nonpathogen - hypothetical protein SACE_5929 1 None None None 134102590 Common - hypothetical protein SACE_6153 13 COG3832 COG3832, Uncharacterized conserved protein Function unknown 134100019 Nonpathogen - hypothetical protein SACE_3481 1 None None None 134099496 Common - cyclase/dehydrase SACE_2954 14 COG5637 COG5637, Predicted integral membrane protein Function unknown 134096701 Common - probable lipase SACE_0083 13 COG3675 COG3675, Predicted lipase Lipid metabolism 134099989 Common - transcriptional regulator, TetR family SACE_3451 92 COG1309 AcrR, Transcriptional regulator Transcription 134102755 Nonpathogen - hypothetical protein SACE_6320 5 COG0456 RimI, Acetyltransferases General function prediction only 134097309 Nonpathogen - hypothetical protein SACE_0702 1 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 134097847 Common - xanthine dehydrogenase accessory factor SACE_1258 116 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 134102895 Common - hypothetical protein SACE_6462 14 None None None 134100296 Common - putative methyltransferase SACE_3761 83 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134101843 Nonpathogen - hypothetical protein SACE_5341 1 None None None 134097702 Common ftsE cell division ATP-binding protein SACE_1106 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 134099582 Common - probable CoA-transferase SACE_3040 115 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 134097905 Nonpathogen - hypothetical protein SACE_1318 2 None None None 134098393 Common - 23S rRNA methyltransferase/RumA SACE_1814 178 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 134098520 Common - metabolite transporter, MFS superfamily SACE_1945 145 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134101955 Common - putative sporulation protein (partial match) SACE_5457 236 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 134103520 Common pstA putative phosphate transport system permease protein SACE_7097 225 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 134099072 Common - short-chain dehydrogenase/reductase SDR SACE_2515 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134100726 Common - cyclase/dehydrase SACE_4193 32 COG5637 COG5637, Predicted integral membrane protein Function unknown 134102695 Common - hypothetical protein SACE_6259 31 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 134099548 Common - hypothetical protein SACE_3006 13 None None None 134099855 Common - ATPase-like protein SACE_3316 32 COG3911 COG3911, Predicted ATPase General function prediction only 134097542 Common - hypothetical protein SACE_0944 15 None None None 134098146 Nonpathogen - hypothetical protein SACE_1560 1 None None None 134101616 Nonpathogen - hypothetical protein SACE_5099 1 None None None 134103701 Common - putative extracellular solute-binding lipoprotein SACE_7279 98 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 134099118 Common - hypothetical protein SACE_2563 18 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134097147 Common - carbon monoxide dehydrogenase small chain SACE_0536 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 134096671 Common - beta-lactamase fold-like Zn-dependent hydrolase SACE_0053 78 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 134103759 Common - methyltransferase SACE_7339 80 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 134098323 Common - hypothetical protein SACE_1741 5 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 134099571 Common - putative hydroxylase SACE_3029 108 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 134097932 Nonpathogen - hypothetical protein SACE_1345 2 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 134099502 Common - integral membrane protein, ribonuclease BN-like family SACE_2960 59 COG1295 Rbn, Predicted membrane protein Function unknown 134097710 Common - putative secreted protein SACE_1115 43 COG4805 COG4805, Uncharacterized protein conserved in bacteria Function unknown 134098589 Common - hypothetical protein SACE_2015 12 COG4392 COG4392, Predicted membrane protein Function unknown 134098208 Common - hypothetical protein SACE_1625 19 None None None 134098575 Common - probable ferredoxin--NADP(+) reductase SACE_2001 188 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 134098059 Common cysN sulfate adenylyltransferase subunit 1 / adenylylsulfate kinase SACE_1473 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 134100592 Common - kynureninase SACE_4057 137 COG3844 COG3844, Kynureninase Amino acid transport and metabolism 134098489 Common - probable amidase SACE_1914 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 134100410 Common - probable metal-dependant glycoprotease SACE_3875 112 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 134099012 Common - CBS domain containing protein SACE_2450 48 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 134103219 Nonpathogen - hypothetical protein SACE_6791 1 None None None 134097959 Common - beta lactamase SACE_1373 20 COG2367 PenP, Beta-lactamase class A Defense mechanisms 134102946 Nonpathogen - hypothetical protein SACE_6513 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 134100345 Common - integral membrane protein SACE_3810 13 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 134101652 Common - arsenical resistance protein/arsenate reductase SACE_5143 133 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 134099079 Common ureD urease accessory protein SACE_2523 6 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 134102986 Common - putative glycosyl transferase (partial match) SACE_6554 41 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 134100799 Common - transposase SACE_4266 30 None None None 134102880 Common mtrB sensory transduction histidine kinase SACE_6446 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 134101659 Common nanT putative sialic acid transporter SACE_5150 182 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134097561 Common merR2 transcriptional regulator, MerR family SACE_0965 99 COG0789 SoxR, Predicted transcriptional regulators Transcription 134101848 Common - RNA binding S1:resolvase, RNase H-like fold SACE_5346 139 COG2183 Tex, Transcriptional accessory protein Transcription 134098380 Common sigA RNA polymerase sigma factor RpoD SACE_1801 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 134096963 Common - cysteine dioxygenase type I SACE_0349 18 COG5553 COG5553, Predicted metal-dependent enzyme of the double-stranded beta helix superfamily General function prediction only 134100012 Common - acyl-CoA dehydrogenase SACE_3474 164 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134096765 Common - two-component system response regulator SACE_0148 218 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134100920 Common mocA oxidoreductase protein SACE_4387 198 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 134096643 Common - acyl-CoA dehydrogenase domain protein SACE_0025 80 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134098392 Common - amino acid permease-associated region SACE_1813 43 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 134098894 Common - MaoC-like dehydratase SACE_2330 79 COG2030 MaoC, Acyl dehydratase Lipid metabolism 134099735 Common leuB 3-isopropylmalate dehydrogenase SACE_3196 221 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 134101320 Nonpathogen - hypothetical protein SACE_4788 1 None None None 134101534 Common - two-component system response regulator SACE_5006 160 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134100344 Nonpathogen - hypothetical protein SACE_3809 1 None None None 134103047 Common tnp9B transposase, IS4 family SACE_6617 23 None None None 134100444 Common - two component transcriptional regulator, LuxR family SACE_3909 184 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134100790 Common aglA alpha-glucosidase SACE_4257 159 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 134103176 Common - hypothetical protein SACE_6746 19 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 134099667 Common - hypothetical protein SACE_3125 11 None None None 134103622 Common - hypothetical protein SACE_7200 116 COG2353 COG2353, Uncharacterized conserved protein Function unknown 134100788 Common - ABC sugar transporter, permease component SACE_4255 152 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 134101304 Common - putative NADH-flavin reductase SACE_4772 45 COG2910 COG2910, Putative NADH-flavin reductase General function prediction only 134101982 Nonpathogen - putative transposase (fragment) SACE_5527 1 None None None 134099068 Common - hypothetical protein SACE_2511 21 COG5516 COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding General function prediction only 134097458 Common - NADH dehydrogenase SACE_0853 190 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 134098602 Common relA GTP pyrophosphokinase SACE_2028 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 134103266 Common tufA elongation factor Tu SACE_6838 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 134097599 Common - hypothetical protein SACE_1003 34 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 134099828 Common - diguanylate cyclase (GGDEF domain) SACE_3289 181 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 134097187 Common - phenazine biosynthesis PhzC/PhzF protein SACE_0577 118 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 134100721 Nonpathogen - hypothetical protein SACE_4188 7 None None None 134096862 Nonpathogen - hypothetical protein SACE_0246 1 None None None 134097997 Common - hypothetical protein SACE_1411 6 None None None 134098942 Common - transcriptional regulator SACE_2378 75 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 134102035 Nonpathogen - hypothetical protein SACE_5585 3 None None None 134098663 Nonpathogen - hypothetical protein SACE_2092 1 None None None 134096933 Common - hypothetical protein SACE_0319 16 None None None 134101648 Common - hypothetical protein SACE_5139 8 None None None 134102201 Nonpathogen - hypothetical protein SACE_5752 1 None None None 134103209 Common rpsI 30S ribosomal protein S9 SACE_6780 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 134097411 Common - ABC transport system substrate-binding protein SACE_0806 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 134103054 Common ctpA cation-transporting ATPase SACE_6624 231 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 134097131 Common pssA CDP-diacylglycerol--serine O-phosphatidyltransferase SACE_0520 134 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 134101007 Common qor quinone oxidoreductase SACE_4474 172 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 134098397 Common cutS two-component sensor (kinase) SACE_1818 208 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 134096626 Common gyrB DNA gyrase subunit B SACE_0008 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 134102915 Common - possible transcriptional regulator, LytR family SACE_6482 59 COG1316 LytR, Transcriptional regulator Transcription 134096735 Common - response regulator, two-component system SACE_0117 177 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 134102910 Common - glycosyl transferase, group 1 SACE_6477 151 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 134099188 Common - sodium/bile acid symporter family protein SACE_2640 55 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 134099352 Nonpathogen - hypothetical protein SACE_2809 1 None None None 134101762 Common argF ornithine carbamoyltransferase SACE_5258 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 134102136 Common sig1 RNA polymerase sigma factor SACE_5686 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 134103150 Common phoD phosphodiesterase/alkaline phosphatase D SACE_6720 61 COG3540 PhoD, Phosphodiesterase/alkaline phosphatase D Inorganic ion transport and metabolism 134099471 Nonpathogen - PE-PGRS family protein SACE_2929 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 134097837 Common - Mycobacterium tuberculosis paralogous family 11 SACE_1248 11 None None None 134102125 Common - dehydrogenase complex, E1 component, beta subunit SACE_5675 219 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 134097261 Common iroB putative glucosyltransferase SACE_0652 34 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 134100808 Common - thioesterase involved in non-ribosomal peptide biosynthesis SACE_4275 51 COG3208 GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 134103043 Common prpB8 putative magnesium or manganese-dependent protein phosphatase SACE_6613 136 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 134098756 Common - hypothetical protein SACE_2186 5 COG1503 eRF1, Peptide chain release factor 1 (eRF1) Translation, ribosomal structure and biogenesis 134101854 Common - short chain dehydrogenase SACE_5352 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134101611 Common - integrase, catalytic region SACE_5090 98 None None None 134101989 Common - probable acyl carrier protein SACE_5539 114 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134100774 Nonpathogen - hypothetical protein SACE_4241 1 None None None 134097644 Common - sugar ABC transporter, ATP-binding protein SACE_1048 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 134101618 Common - hypothetical protein SACE_5101 17 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 134100956 Nonpathogen - hypothetical protein SACE_4423 1 None None None 134103202 Common - PE-PGRS family protein SACE_6773 4 COG4907 COG4907, Predicted membrane protein Function unknown 134098220 Common - putative NAD dependent epimerase/dehydratase family SACE_1637 105 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 134096688 Common - aminoglycoside phosphotransferase SACE_0070 7 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 134102810 Common - hypothetical protein SACE_6376 2 COG2149 COG2149, Predicted membrane protein Function unknown 134097473 Common - putative type I restriction system adenine methylase SACE_0872 92 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 134099599 Common - pentachlorophenol monooxygenase SACE_3057 71 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 134101307 Common - transcriptional regulator, MerR family SACE_4775 78 COG0789 SoxR, Predicted transcriptional regulators Transcription 134097384 Nonpathogen - hypothetical protein SACE_0778 1 None None None 134102909 Common - glycosyltransferase domain containing protein SACE_6476 159 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 134099916 Common megL methionine gamma-lyase SACE_3377 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 134097719 Common - hypothetical protein SACE_1124 11 None None None 134098442 Nonpathogen - hypothetical protein SACE_1866 2 None None None 134100547 Common - major facilitator superfamily MFS_1 SACE_4012 152 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 134097120 Nonpathogen - hypothetical protein SACE_0509 1 COG1289 COG1289, Predicted membrane protein Function unknown 134099138 Common - N-acyl-D-amino-acid deacylase SACE_2583 62 COG3653 COG3653, N-acyl-D-aspartate/D-glutamate deacylase Secondary metabolites biosynthesis, transport, and catabolism 134097482 Common - hypothetical protein SACE_0884 11 None None None 134097903 Nonpathogen snp3 secreted extracellular small neutral protease SACE_1316 3 None None None 134103768 Common rplI 50S ribosomal protein L9 SACE_7348 215 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 134096993 Common kduD 2-deoxy-D-gluconate 3-dehydrogenase SACE_0380 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134097823 Common - hypothetical protein SACE_1234 99 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 134099150 Common - polyketide synthase type I SACE_2595 223 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134101208 Common - IS402-like transposase SACE_4676 20 None None None 134101911 Common - transcriptional regulator, XRE family SACE_5410 6 None None None 134102149 Common - TetR-family transcriptional regulator SACE_5700 35 COG1309 AcrR, Transcriptional regulator Transcription 134100026 Common - CBS domain protein SACE_3488 131 COG0517 COG0517, FOG: CBS domain General function prediction only 134100172 Common - probable transposase SACE_3634 5 None None None 134100618 Common - hypothetical protein SACE_4083 26 COG5516 COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding General function prediction only 134096880 Common - two component system histidine kinase SACE_0265 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 134098970 Common - acetyl-CoA synthetase SACE_2408 221 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 134100858 Common - radical SAM SACE_4325 73 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 134103174 Common blaB2 metallo-beta-lactamase SACE_6744 56 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 134102625 Common - putative pyridoxal-phosphate-dependent aminotransferase SACE_6188 230 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 134103413 Nonpathogen - hypothetical protein SACE_6987 3 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134098627 Common tnp transposase, ISlxx5 SACE_2057 63 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 134097872 Common - protein kinase SACE_1285 148 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 134097947 Common - ATP-dependent Clp protease proteolytic subunit SACE_1361 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 134100645 Nonpathogen - hypothetical protein SACE_4111 5 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134096932 Nonpathogen - hypothetical protein SACE_0318 1 None None None 134102251 Common nadA quinolinate synthetase SACE_5803 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 134100215 Common ogt1 putative methylated-DNA--protein-cysteine S-methyltransferase SACE_3677 110 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 134100078 Nonpathogen - hypothetical protein SACE_3540 1 None None None 134101187 Common - protein kinase/transcriptional regulator, LuxR family SACE_4654 27 COG3903 COG3903, Predicted ATPase General function prediction only 134098280 Common arsA arsenite-transporting ATPase SACE_1698 58 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 134101730 Common - hypothetical protein SACE_5226 10 COG3940 COG3940, Predicted beta-xylosidase General function prediction only 134098926 Common mce5E putative Mce family protein SACE_2362 19 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 134103629 Common hspR heat shock regulator SACE_7207 58 COG0789 SoxR, Predicted transcriptional regulators Transcription 134100350 Common - NUDIX hydrolase SACE_3815 31 COG4119 COG4119, Predicted NTP pyrophosphohydrolase DNA replication, recombination, and repair / General function prediction only 134098406 Common - IS21 family transposase SACE_1828 31 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 134099353 Common - hypothetical protein SACE_2810 10 None None None 134098598 Common - preprotein translocase, YajC subunit SACE_2024 10 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 134100169 Nonpathogen - hypothetical protein SACE_3631 2 None None None 134098156 Common - hypothetical protein SACE_1570 9 None None None 134099933 Common - ATP-dependent DNA ligase SACE_3394 66 COG3285 COG3285, Predicted eukaryotic-type DNA primase DNA replication, recombination, and repair 134097186 Common - hypothetical protein SACE_0576 41 COG3304 COG3304, Predicted membrane protein Function unknown 134100286 Common - protein of unknown function DUF1697 SACE_3751 43 COG3797 COG3797, Uncharacterized protein conserved in bacteria Function unknown 134099006 Common uspA1 putative universal stress protein SACE_2444 57 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 134100010 Common - hypothetical protein SACE_3472 12 None None None 134100543 Common catI 3-oxoadipate:succinyl-CoA transferase, A subunit SACE_4008 43 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 134100563 Common - ABC transporter protein, ATP-binding component SACE_4028 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 134099080 Common ureG urease accessory protein SACE_2524 151 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 134097279 Nonpathogen - hypothetical protein SACE_0670 1 None None None 134102193 Common - ABC-type transporter, permease component SACE_5744 183 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 134097381 Common moeA1 molybdopterin biosynthesis protein MoeA SACE_0775 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 134098262 Common - integral membrane protein SACE_1679 16 None None None 134098794 Common - putative glycine betaine/proline ABC transporter SACE_2225 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 134100268 Common - transcriptional regulator, XRE family SACE_3733 6 None None None 134101094 Common - FAD dependent oxidoreductase SACE_4561 18 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 134098675 Common - hypothetical protein SACE_2105 10 COG5522 COG5522, Predicted integral membrane protein Function unknown 134100084 Common - putative phenylacetic acid degradation protein SACE_3546 42 COG3396 COG3396, Uncharacterized conserved protein Function unknown 134100941 Common - probable multidrug ABC transporter, permease SACE_4408 27 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134101572 Common ligI 2-pyrone-4,6-dicarboxylic acid hydrolase SACE_5048 39 COG3618 COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 134098950 Common - probable 1,3-propanediol dehydrogenase SACE_2386 169 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 134102715 Common atpC F0F1 ATP synthase subunit epsilon SACE_6279 159 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 134097127 Common - possible glycoprotein SACE_0516 5 COG5373 COG5373, Predicted membrane protein Function unknown 134098863 Common xerD integrase/recombinase SACE_2295 215 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 134100264 Nonpathogen - hypothetical protein SACE_3729 1 None None None 134101646 Common - oxidoreductase SACE_5137 148 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134100772 Common - transposase for IS3517 SACE_4239 11 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 134097577 Common - ABC transporter substrate-binding protein SACE_0981 85 COG4143 TbpA, ABC-type thiamine transport system, periplasmic component Coenzyme metabolism 134098553 Common - delta-1-pyrroline-5-carboxylate dehydrogenase precursor SACE_1979 219 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 134098731 Common ctaB protoheme IX farnesyltransferase SACE_2161 183 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 134102905 Common wbbL putative dTDP-rhamnosyl transferase SACE_6472 113 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 134100199 Common - ribonuclease SACE_3661 89 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 134102438 Common dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase SACE_5994 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 134098655 Common pyrF orotidine-5prime-phosphate decarboxylase SACE_2084 66 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 134100651 Common sfbB ABC transporter ATP-binding protein SACE_4117 163 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 134101295 Common - NAD/NADP octopine/nopaline dehydrogenase SACE_4763 26 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 134099155 Common - hypothetical protein SACE_2600 8 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 134099985 Common - acyl-CoA synthetase SACE_3447 218 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134103152 Common estC esterase SACE_6722 30 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134103743 Common - hypothetical protein SACE_7321 16 None None None 134101180 Nonpathogen - UbiA prenyltransferase SACE_4647 11 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 134100030 Common - peptidase S1 and S6, chymotrypsin/Hap SACE_3492 220 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 134100151 Common - hypothetical protein SACE_3613 8 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 134097328 Common - transposase SACE_0722 74 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 134102407 Common - precorrin-6y C5,15-methyltransferase, subunit CbiE SACE_5961 112 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 134098826 Common - oxidoreductase, short-chain dehydrogenase/reductase family SACE_2257 195 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 134099612 Nonpathogen - response regulator receiver protein SACE_3070 2 None None None 134102889 Common - cation diffusion facilitator family transporter SACE_6456 60 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 134098062 Common nirA ferredoxin--nitrite reductase SACE_1476 175 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 134103345 Common - pentapeptide repeats domain protein SACE_6918 63 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 134103060 Common - hypothetical protein SACE_6630 2 None None None 134103328 Common nuoC NADH dehydrogenase subunit C SACE_6900 174 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 134101022 Common - probable hydroxyacylglutathione hydrolase SACE_4489 213 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 134098505 Common - hypothetical protein SACE_1930 18 COG2331 COG2331, Uncharacterized protein conserved in bacteria Function unknown 134097112 Common - putative GntR-family transcriptional regulator SACE_0500 124 COG2188 PhnF, Transcriptional regulators Transcription 134101044 Common fprC ferredoxin reductase SACE_4511 224 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 134103782 Nonpathogen - hypothetical protein SACE_7362 1 None None None 134101953 Common cebE putative sugar binding secreted protein SACE_5455 39 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 134096817 Common - putative ABC transport system, ATP-binding protein SACE_0200 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 134097439 Common - transcriptional regulator, MazG family SACE_0834 154 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 134102084 Common - putative regulatory protein SACE_5634 12 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 134103108 Nonpathogen - hypothetical protein SACE_6678 1 None None None 134102726 Common - similar to hydrolase or acyltransferase (alpha/beta hydrolase superfamily) SACE_6290 160 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134097991 Common - hypothetical protein SACE_1405 40 COG5011 COG5011, Uncharacterized protein conserved in bacteria Function unknown 134097727 Nonpathogen - hypothetical protein SACE_1132 1 None None None 134098274 Common - NLP/P60-family protein SACE_1692 117 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 134100064 Common - alpha/beta hydrolase fold SACE_3526 86 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134102494 Common ffh signal recognition particle GTPase SACE_6057 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 134099668 Common fadE13 acyl-CoA dehydrogenase SACE_3126 155 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134103499 Nonpathogen - hypothetical protein SACE_7074 1 None None None 134102037 Nonpathogen - hypothetical protein SACE_5587 1 None None None 134100735 Common - putative oxidoreductase SACE_4202 92 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 134099521 Nonpathogen - hypothetical protein SACE_2979 1 None None None 134101194 Common - 4-oxalocrotonate tautomerase SACE_4661 29 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 134098098 Nonpathogen - acetyltransferase (GNAT) family SACE_1512 15 COG3153 COG3153, Predicted acetyltransferase General function prediction only 134098646 Common efp elongation factor P SACE_2075 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 134103159 Common gcl glyoxylate carboligase SACE_6729 221 COG3960 COG3960, Glyoxylate carboligase General function prediction only 134103232 Common rpsD 30S ribosomal protein S4 SACE_6804 247 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 134098961 Common prsA ribose-phosphate pyrophosphokinase SACE_2398 220 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 134097864 Common - ABC-transport protein, membrane component SACE_1275 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 134100423 Common corA CorA-like putative magnesium transport protein SACE_3888 144 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 134100863 Common hopD putative squalene/phytoene synthase SACE_4330 110 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 134097008 Common hpt hypoxanthine-guanine phosphoribosyltransferase SACE_0395 136 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 134100071 Common - hypothetical protein SACE_3533 10 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 134096723 Nonpathogen - hypothetical protein SACE_0105 1 None None None 134100624 Common - response regulator, two-component system SACE_4089 207 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 134097790 Common pncB nicotinate phosphoribosyltransferase SACE_1200 115 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 134100380 Common - FHA domain containing protein SACE_3845 64 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 134098327 Common gluB1 putative glutamate binding protein SACE_1745 173 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 134102110 Common rbsC putative D-ribose ABC transporter permease protein SACE_5660 150 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 134099744 Common - transmembrane efflux protein SACE_3205 15 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134103083 Common - putative transporter SACE_6653 23 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134097951 Common - formate dehydrogenase family accessory protein FdhD SACE_1365 136 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 134099671 Common - transmembrane protein SACE_3129 47 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 134103572 Common purC phosphoribosylaminoimidazole-succinocarboxamide synthase SACE_7150 111 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 134103249 Common rplF 50S ribosomal protein L6 SACE_6821 243 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 134103391 Common regX3 two-component response regulator SACE_6965 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 134097984 Nonpathogen sti1 protease inhibitor protein SACE_1398 1 None None None 134102009 Nonpathogen - hypothetical protein SACE_5559 1 None None None 134102479 Common xerC integrase/recombinase SACE_6041 218 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 134099990 Nonpathogen - hypothetical protein SACE_3452 1 None None None 134101255 Common - SSS sodium solute transporter superfamily SACE_4723 129 COG4147 DhlC, Predicted symporter General function prediction only 134102514 Common - bicyclomycin resistance protein TcaB SACE_6077 141 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134098919 Nonpathogen - hypothetical protein SACE_2355 2 None None None 134102129 Common - regulatory protein SACE_5679 15 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 134099034 Common - integral membrane protein SACE_2473 51 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 134100128 Common bacA undecaprenyl-diphosphatase SACE_3590 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 134098684 Common - ribosomal RNA small subunit methyltransferase SACE_2114 206 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 134101076 Common - secreted protein SACE_4543 63 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 134101587 Common - putative IS110 transposase/integrase SACE_5063 89 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 134096758 Nonpathogen - integral membrane protein SACE_0140 3 None None None 134100059 Common - oxidoreductase domain protein SACE_3521 93 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 134097097 Common ectA putative L-2,4-diaminobutyric acid acetyltransferase SACE_0483 35 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 134102111 Nonpathogen - hypothetical protein SACE_5661 1 None None None 134098215 Common - putative TetR-type transcriptional regulator SACE_1632 161 COG1309 AcrR, Transcriptional regulator Transcription 134098003 Common proB gamma-glutamate kinase SACE_1417 189 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 134100602 Common narI nitrate reductase gamma chain SACE_4067 61 COG2181 NarI, Nitrate reductase gamma subunit Energy production and conversion 134102635 Common - DegV family protein SACE_6198 47 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 134100021 Common - hypothetical protein SACE_3483 9 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 134100746 Common - putative FAD-binding dehydrogenase SACE_4213 27 COG3573 COG3573, Predicted oxidoreductase General function prediction only 134101430 Common glpX fructose-bisphosphatase, class II SACE_4900 68 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 134096751 Nonpathogen - hypothetical protein SACE_0133 1 COG4820 EutJ, Ethanolamine utilization protein, possible chaperonin Amino acid transport and metabolism 134098429 Nonpathogen - hypothetical protein SACE_1853 1 None None None 134097089 Nonpathogen - hypothetical protein SACE_0475 1 None None None 134101218 Nonpathogen - hypothetical protein SACE_4686 1 None None None 134097706 Nonpathogen - hypothetical protein SACE_1111 1 None None None 134103789 Nonpathogen - hypothetical protein SACE_7369 1 None None None 134100295 Common - putative ATPase of the ABC class SACE_3760 27 COG3044 COG3044, Predicted ATPase of the ABC class General function prediction only 134101882 Common fadE31 putative acyl-CoA dehydrogenase SACE_5380 150 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134098531 Common cvnD6 ATP/GTP-binding protein SACE_1956 32 COG2229 COG2229, Predicted GTPase General function prediction only 134099466 Common - ROK-family transcriptional regulator SACE_2924 77 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 134100328 Common - von Willebrand factor, type A SACE_3793 74 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 134101738 Common cmk cytidylate kinase SACE_5234 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 134097251 Common pdxH pyridoxamine 5'-phosphate oxidase SACE_0641 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 134096683 Common - TetR-family transcriptional regulator SACE_0065 43 COG1309 AcrR, Transcriptional regulator Transcription 134100673 Common - type I modular polyketide synthase SACE_4140 210 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134102359 Common dapB dihydrodipicolinate reductase SACE_5912 216 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 134102221 Common - activator of HSP90 ATPase 1 family protein SACE_5772 44 COG3832 COG3832, Uncharacterized conserved protein Function unknown 134101401 Common - pyridoxal-5'-phosphate-dependent enzyme, beta subunit SACE_4871 122 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 134097300 Common cvnD6 ATP/GTP-binding protein SACE_0693 31 COG2229 COG2229, Predicted GTPase General function prediction only 134098742 Common - possible membrane protein SACE_2172 14 None None None 134101223 Common - putative secreted serine protease SACE_4691 113 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 134098240 Common - FAD linked oxidase domain protein SACE_1657 75 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 134101482 Common - hypothetical protein SACE_4952 234 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 134096719 Common - two component system response regulator SACE_0101 209 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 134098283 Nonpathogen - hypothetical protein SACE_1701 1 None None None 134098202 Common - glutamine amidotransferase class-I SACE_1618 111 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 134100825 Common - putative ornithine carbamoyltransferase SACE_4292 231 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 134096832 Common - possible lipoprotein SACE_0215 8 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 134097533 Common xseB putative exodeoxyribonuclease VII small subunit SACE_0935 26 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 134100200 Common estC carboxylesterase SACE_3662 41 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 134099842 Common - aldo/keto reductase SACE_3303 184 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 134097270 Common - xanthine/uracil/vitamin C permease SACE_0661 120 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 134097686 Common - peptidase M16-like SACE_1090 154 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 134099904 Common cpo,cpoF non-heme chloroperoxidase SACE_3365 100 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134101579 Common hrmI hexuronic acid isomerase SACE_5055 60 COG1904 UxaC, Glucuronate isomerase Carbohydrate transport and metabolism 134102172 Common - protein of unknown function DUF1486 SACE_5723 11 COG5485 COG5485, Predicted ester cyclase General function prediction only 134096730 Common - RNA polymerase, sigma-70 factor, ECF subfamily SACE_0112 6 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 134102825 Common - LysR-family transcriptional regulator SACE_6391 168 COG0583 LysR, Transcriptional regulator Transcription 134099163 Nonpathogen - hypothetical protein SACE_2614 2 None None None 134098238 Common - RNA-binding S4 SACE_1655 36 COG2501 COG2501, Uncharacterized conserved protein Function unknown 134099849 Common - putative signal transduction histidine kinase SACE_3310 112 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 134103462 Common acdH acyl-CoA dehydrogenase SACE_7037 166 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134096631 Common - lignostilbene-alpha/beta-dioxygenase SACE_0013 36 COG3670 COG3670, Lignostilbene-alpha,beta-dioxygenase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 134098445 Common - hypothetical protein SACE_1869 2 None None None 134102488 Common rimM 16S rRNA processing protein SACE_6051 61 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 134099087 Common - transposase, mutator type SACE_2531 82 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 134099184 Common - mandelate racemase/muconate lactonizing enzyme SACE_2636 128 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 134100452 Common - undecaprenyl-phosphate galactosephosphotransferase SACE_3917 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 134097898 Common - hypothetical protein SACE_1311 11 None None None 134099997 Common ygbK hypothetical protein SACE_3459 71 COG3395 COG3395, Uncharacterized protein conserved in bacteria Function unknown 134103532 Nonpathogen - hypothetical protein SACE_7109 1 None None None 134102897 Common whiB2 putative transcriptional regulator (WhiB family) SACE_6464 19 None None None 134100192 Common - hypothetical protein SACE_3654 10 COG1846 MarR, Transcriptional regulators Transcription 134101767 Common - N-acetyl-gamma-glutamyl-phosphate reductase SACE_5263 213 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 134101893 Common - oxidoreductase short-chain dehydrogenase/reductase family SACE_5391 218 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 134097741 Common - putative sensor-like histidine kinase SACE_1149 31 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 134100929 Common zwf3 6-phosphogluconate dehydrogenase SACE_4396 185 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 134096939 Common - metallo-beta-lactamase superfamily protein SACE_0325 195 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 134102298 Common murC UDP-N-acetylmuramate--L-alanine ligase SACE_5850 209 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 134102013 Nonpathogen - hypothetical protein SACE_5563 1 None None None 134103292 Common yrbE4B putative ABC transport system permease protein SACE_6864 147 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 134100660 Common - predicted acyl-CoA transferase/carnitine dehydratase SACE_4127 114 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 134098751 Common - MOSC domain containing protein SACE_2181 32 COG3217 COG3217, Uncharacterized Fe-S protein General function prediction only 134102027 Common - hypothetical protein SACE_5577 8 None None None 134103032 Common - AP endonuclease, family 1:exodeoxyribonuclease III xth SACE_6601 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 134102425 Common - regulatory protein GntR, HTH SACE_5981 137 COG2186 FadR, Transcriptional regulators Transcription 134099844 Common - LysR-family transcriptional regulator SACE_3305 87 COG0583 LysR, Transcriptional regulator Transcription 134099679 Common - repressor in the phenylacetic acid catabolism SACE_3137 29 COG3327 PaaX, Phenylacetic acid-responsive transcriptional repressor Transcription 134100248 Common - phospholipase/carboxylesterase family protein SACE_3712 38 COG0400 COG0400, Predicted esterase General function prediction only 134097156 Common - ATP-dependent DNA helicase SACE_0545 85 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 134098090 Common - serine protease inhibitor serpin homolog SACE_1504 29 COG4826 COG4826, Serine protease inhibitor Posttranslational modification, protein turnover, chaperones 134101713 Common embC arabinosyl transferase SACE_5208 5 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 134100716 Nonpathogen - hypothetical protein SACE_4183 1 None None None 134098878 Common tnp9B transposase, IS4 family SACE_2313 13 None None None 134102304 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase SACE_5856 208 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 134099632 Common helZ2 SNF2/RAD54 family helicase SACE_3090 132 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 134100184 Common - NAD-dependent epimerase/dehydratase SACE_3646 109 COG2910 COG2910, Putative NADH-flavin reductase General function prediction only 134100177 Common - serine--glyoxylate aminotransferase SACE_3639 64 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 134100198 Nonpathogen - hypothetical protein SACE_3660 1 None None None 134097256 Common - possible transcriptional regulator, TetR family SACE_0646 11 COG1309 AcrR, Transcriptional regulator Transcription 134098547 Nonpathogen - candidate polysaccharide lyase, polysaccharide lyase family 14 protein SACE_1973 2 None None None 134099222 Common - glyoxalase/bleomycin resistance protein/dioxygenase SACE_2676 43 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 134102703 Common - amino acid ABC transporter, permease protein SACE_6267 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 134098357 Common - iron (metal) dependent repressor, DtxR family SACE_1776 65 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 134096946 Common - redoxin SACE_0332 48 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 134101332 Common - hypothetical protein SACE_4803 176 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 134103355 Common - GntR-family transcriptional regulator SACE_6928 173 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 134102612 Common - amino acid-binding ACT SACE_6175 10 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 134097886 Nonpathogen - hypothetical protein SACE_1299 1 None None None 134098883 Common - transposase, IS4 SACE_2318 43 None None None 134097346 Common - acetyltransferase, GNAT family SACE_0740 29 COG3981 COG3981, Predicted acetyltransferase General function prediction only 134102348 Common pkaI serine/threonine protein kinase SACE_5901 155 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 134098567 Common - integral membrane protein SACE_1993 9 None None None 134101429 Nonpathogen - membrane protein SACE_4899 9 None None None 134100291 Common clpA clp protease ATP binding subunit SACE_3756 222 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 134099444 Nonpathogen - hypothetical protein SACE_2902 1 None None None 134103420 Common - possible membrane protein SACE_6994 49 COG2733 COG2733, Predicted membrane protein Function unknown 134097377 Nonpathogen - hypothetical protein SACE_0771 1 None None None 134099552 Common - putative copper resistance protein (partial match) SACE_3010 14 COG2372 CopC, Uncharacterized protein, homolog of Cu resistance protein CopC General function prediction only 134096996 Common - hypothetical protein SACE_0383 11 None None None 134101694 Common - thiamine pyrophosphate-requiring enzyme SACE_5186 222 COG3962 COG3962, Acetolactate synthase Amino acid transport and metabolism 134096687 Common - regulator SACE_0069 6 None None None 134102430 Common - hypothetical protein SACE_5986 2 None None None 134102273 Common - cysteine desulfurase SACE_5825 220 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 134097132 Common psd phosphatidylserine decarboxylase proenzyme SACE_0521 95 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 134097788 Common - hypothetical protein SACE_1198 3 None None None 134103646 Common dcd deoxycytidine triphosphate deaminase SACE_7224 162 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 134101261 Common acsA acetyl-CoA synthetase SACE_4729 216 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 134097025 Common fepG Fe(3+) enterobactin transport system permease protein SACE_0412 173 COG4779 FepG, ABC-type enterobactin transport system, permease component Inorganic ion transport and metabolism 134102644 Common echA enoyl-CoA hydratase-isomerase SACE_6207 189 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 134100335 Common - assimilatory nitrate reductase catalytic subunit SACE_3800 185 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 134096846 Common cypA cytochrome P450-like enzyme SACE_0229 85 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134099411 Common rifN rifN AHBA kinase SACE_2869 47 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 134099322 Common - organic anion transporter family protein SACE_2777 145 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134099364 Common - oxidoreductase alpha subunit SACE_2821 73 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 134097058 Common - conserved hypothetical protein (putative membrane protein) SACE_0445 8 COG4894 COG4894, Uncharacterized conserved protein Function unknown 134099459 Common argG argininosuccinate synthase SACE_2917 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 134101828 Common - peptidase C45, acyl-coenzyme A/6-aminopenicillanic acid acyl-transferase SACE_5325 14 None None None 134103660 Common - hypothetical protein SACE_7238 43 COG1993 COG1993, Uncharacterized conserved protein Function unknown 134098491 Nonpathogen - major facilitator superfamily MFS_1 SACE_1916 2 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 134098161 Nonpathogen - hypothetical protein SACE_1575 1 None None None 134097443 Common eno phosphopyruvate hydratase SACE_0838 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 134097192 Common - FtsK/SpoIIIE family protein SACE_0582 191 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 134099270 Common - hypothetical protein SACE_2725 2 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 134101695 Common - myo-inositol catabolism IolB protein SACE_5187 51 COG3718 IolB, Uncharacterized enzyme involved in inositol metabolism Carbohydrate transport and metabolism 134096978 Common - HAD-superfamily subfamily IB, PSPase-like protein SACE_0365 70 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 134096897 Common - aspartate-semialdehyde dehydrogenase, USG-1 related SACE_0283 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 134099568 Common - putative transcriptional activator of the SARP family SACE_3026 11 COG3629 DnrI, DNA-binding transcriptional activator of the SARP family Signal transduction mechanisms 134097958 Common - transcriptional regulator, LysR family SACE_1372 108 COG0583 LysR, Transcriptional regulator Transcription 134097781 Common - ABC transporter, ATP-binding protein SACE_1191 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 134101108 Common pksF polyketide beta-ketoacyl:acyl carrier protein synthase SACE_4575 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134098717 Common - electron transport protein SACE_2147 17 None None None 134099495 Common racX putative aspartate/glutamate racemase SACE_2953 71 COG1794 RacX, Aspartate racemase Cell envelope biogenesis, outer membrane 134102580 Common leuD 3-isopropylmalate dehydratase small subunit SACE_6143 209 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 134099122 Common insI IS30 transposase SACE_2567 63 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 134101914 Nonpathogen - ABC transporter, substrate binding protein SACE_5413 11 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 134097318 Nonpathogen - putative erythromycin esterase SACE_0712 2 None None None 134101720 Common fucA L-fuculose-phosphate aldolase SACE_5215 170 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 134098183 Nonpathogen - hypothetical protein SACE_1599 1 None None None 134099092 Common - transposase IS116/IS110/IS902 family protein SACE_2536 17 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 134101452 Nonpathogen - hypothetical protein SACE_4922 1 None None None 134100231 Common - protein of unknown function DUF849 SACE_3693 8 COG3246 COG3246, Uncharacterized conserved protein Function unknown 134101625 Nonpathogen - hypothetical protein SACE_5111 1 None None None 134099798 Common - diguanylate cyclase/phosphodiesterase SACE_3259 176 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 134098701 Common - protein of unknown function DUF6, transmembrane SACE_2131 11 None None None 134101681 Common - D-galactarate dehydratase/altronate hydrolase-like SACE_5173 73 COG2721 UxaA, Altronate dehydratase Carbohydrate transport and metabolism 134101845 Common - AMP-dependent synthetase and ligase SACE_5343 215 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 134097917 Common - probable alpha-glucosidase SACE_1330 56 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 134099245 Common - alpha/beta hydrolase fold SACE_2699 121 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134099193 Common - dicarboxylate carrier MatC domain protein SACE_2646 18 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 134097629 Common tatB sec-independent translocase SACE_1033 26 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 134100124 Common lplA lipoate-protein ligase A SACE_3586 79 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 134099658 Common - 2,5-diketo-D-gluconic acid reductase SACE_3116 102 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 134101441 Common nirB assimilatory nitrite reductase large subunit SACE_4911 175 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 134101749 Common - transcriptional regulator, XRE family SACE_5245 6 None None None 134103181 Common - amine oxidase SACE_6751 71 COG2907 COG2907, Predicted NAD/FAD-binding protein General function prediction only 134102673 Common fadA4 acetyl-CoA acetyltransferase SACE_6236 173 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 134101448 Common - putative IS630 family transposase SACE_4918 15 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 134101678 Common ansP L-asparagine permease SACE_5170 167 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 134097854 Common - regulatory protein SACE_1265 30 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 134103650 Nonpathogen - hypothetical protein SACE_7228 2 None None None 134096655 Common - hypothetical protein SACE_0037 5 None None None 134102996 Common deoC putative deoxyribose-phosphate aldolase SACE_6564 134 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 134102267 Common pntAb putative pyridine nucleotide transhydrogenase alpha 2 subunit SACE_5819 117 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 134099263 Nonpathogen - hypothetical protein SACE_2718 1 None None None 134099603 Common - NADH ubiquinone oxidoreductase, 20 kDa subunit SACE_3061 77 COG1740 HyaA, Ni,Fe-hydrogenase I small subunit Energy production and conversion 134102610 Common gatA glutamyl-tRNA(Gln) amidotransferase, subunit A SACE_6173 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 134101679 Common - L-asparaginase II SACE_5171 46 COG4448 AnsA, L-asparaginase II Amino acid transport and metabolism 134102197 Common trpA tryptophan synthase alpha chain SACE_5748 216 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 134098361 Common - alpha/beta hydrolase fold SACE_1781 33 COG4757 COG4757, Predicted alpha/beta hydrolase General function prediction only 134101755 Nonpathogen - hypothetical protein SACE_5251 1 None None None 134097090 Nonpathogen - hypothetical protein SACE_0476 1 None None None 134098636 Common aroK shikimate kinase I SACE_2066 165 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 134101599 Nonpathogen - hypothetical protein SACE_5076 1 None None None 134098631 Common - protein-N(pi)-phosphohistidine--sugar phosphotransferase SACE_2061 48 COG1264 PtsG, Phosphotransferase system IIB components Carbohydrate transport and metabolism 134102528 Common - asparagine synthase (glutamine-hydrolyzing) SACE_6091 172 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 134103737 Nonpathogen - hypothetical protein SACE_7315 2 None None None 134100882 Common - transcriptional regulator, GntR family SACE_4349 121 COG1802 GntR, Transcriptional regulators Transcription 134101121 Common - L-carnitine dehydratase/bile acid-inducible protein F SACE_4588 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 134096954 Common - possible lyase SACE_0340 45 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 134101422 Common - alpha/beta hydrolase SACE_4892 102 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134099232 Common - transcriptional regulator, AsnC family SACE_2686 8 COG1522 Lrp, Transcriptional regulators Transcription 134100766 Common ramB putative ABC transporter SACE_4233 245 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 134101011 Common cdaR transcriptional regulator SACE_4478 20 COG3629 DnrI, DNA-binding transcriptional activator of the SARP family Signal transduction mechanisms 134098178 Nonpathogen - hypothetical protein SACE_1594 1 None None None 134097357 Common rpsR2 30S ribosomal protein S18 SACE_0751 214 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 134097662 Common - hypothetical protein SACE_1066 15 None None None 134101669 Common - hypothetical protein SACE_5161 4 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 134100561 Common - hypothetical protein SACE_4026 58 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 134096768 Common - phage tail assembly-like protein SACE_0151 14 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 134098998 Common uspA3 universal stress protein family SACE_2436 6 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 134097462 Nonpathogen - hypothetical protein SACE_0858 1 None None None 134100884 Common - transketolase, C-terminal subunit SACE_4351 227 COG3958 COG3958, Transketolase, C-terminal subunit Carbohydrate transport and metabolism 134101875 Common - glucose-methanol-choline oxidoreductase SACE_5373 89 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 134102576 Common - hypothetical protein SACE_6139 10 COG1920 COG1920, Uncharacterized conserved protein Function unknown 134098698 Common - branched-chain amino acid aminotransferase SACE_2128 158 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 134101470 Common - fructuronate reductase SACE_4940 88 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 134101909 Common - 3-hydroxyacyl-CoA dehydrogenase, NAD-binding SACE_5408 111 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 134101130 Common - MFS transporter, phthalate permease family SACE_4597 137 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 134097657 Nonpathogen - hypothetical protein SACE_1061 1 None None None 134103450 Nonpathogen - hypothetical protein SACE_7025 1 None None None 134103427 Common - transcriptional regulator/aminotransferase SACE_7001 225 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 134103676 Nonpathogen - hypothetical protein SACE_7254 1 None None None 134096927 Common - FAD-binding 9, siderophore-interacting domain protein SACE_0313 63 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 134097226 Common - hypothetical protein SACE_0616 12 COG4219 MecR1, Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component Transcription / Signal transduction mechanisms 134098689 Common - amino acid permease-associated region SACE_2119 170 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 134096664 Common - peptidoglycan glycosyltransferase SACE_0046 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 134100258 Nonpathogen - terpene synthase, metal-binding SACE_3722 8 None None None 134103385 Common proC pyrroline-5-carboxylate reductase SACE_6959 214 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 134099765 Common - hypothetical protein SACE_3226 6 COG4285 COG4285, Uncharacterized conserved protein Function unknown 134099346 Common - probable conserved integral membrane alanine and leucine rich protein SACE_2801 14 None None None 134100109 Common - hypothetical protein SACE_3571 29 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 134100482 Common - monooxygenase, FAD-binding SACE_3947 76 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 134097496 Common - lipolytic enzyme, G-D-S-L SACE_0898 23 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 134101113 Common - hypothetical protein SACE_4580 28 COG1511 COG1511, Predicted membrane protein Function unknown 134103338 Common menF isochorismate mutase SACE_6911 222 COG1169 MenF, Isochorismate synthase Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134098484 Common - transcriptional regulator, GntR family SACE_1909 138 COG1802 GntR, Transcriptional regulators Transcription 134097026 Common fepC Fe(3+) enterobactin transport ATP-binding protein SACE_0413 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 134097030 Common tpase1 transposase SACE_0417 97 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 134097281 Common - lipase SACE_0673 94 COG2267 PldB, Lysophospholipase Lipid metabolism 134098774 Common - phosphatidylinositol 3-and 4-kinase, catalytic SACE_2204 18 None None None 134103431 Common - secreted protein SACE_7006 63 COG1273 COG1273, Uncharacterized conserved protein Function unknown 134097165 Common - ABC transporter, permease component SACE_0554 130 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 134100212 Common mdh malate dehydrogenase SACE_3674 119 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 134103408 Common purU formyltetrahydrofolate deformylase SACE_6982 220 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 134100434 Common adoK adenosine kinase SACE_3899 55 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 134099381 Common fdxB ferredoxin SACE_2838 23 COG1141 Fer, Ferredoxin Energy production and conversion 134100355 Common yjhP putative SAM-dependent methyltransferase SACE_3820 22 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 134100468 Common - GntR-family transcriptional regulator SACE_3933 129 COG2186 FadR, Transcriptional regulators Transcription 134102285 Common - short chain dehydrogenase SACE_5837 118 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134100494 Common - TetR-family transcriptional regulator SACE_3959 14 COG1309 AcrR, Transcriptional regulator Transcription 134102663 Common - LacI-family transcriptional regulator SACE_6226 124 COG1609 PurR, Transcriptional regulators Transcription 134103481 Common - transcriptional regulator, TetR family SACE_7056 73 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 134097843 Common - hypothetical protein SACE_1254 5 None None None 134099449 Common - sugar phosphate isomerase/epimerase SACE_2907 31 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 134102773 Common cvnD6 ATP/GTP-binding protein SACE_6339 30 COG2229 COG2229, Predicted GTPase General function prediction only 134098768 Common - hypothetical protein SACE_2198 2 None None None 134101282 Nonpathogen - hypothetical protein SACE_4750 1 None None None 134100330 Common - probable transcriptional regulator, MoxR family SACE_3795 177 COG0714 COG0714, MoxR-like ATPases General function prediction only 134097139 Common - putative copper homeostasis protein CutC SACE_0528 50 COG3142 CutC, Uncharacterized protein involved in copper resistance Inorganic ion transport and metabolism 134100948 Common - ABC transporter, permease component SACE_4415 192 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 134098710 Common - hypothetical protein SACE_2140 88 COG0391 COG0391, Uncharacterized conserved protein Function unknown 134101860 Common - integral membrane protein SACE_5358 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 134098814 Nonpathogen - hypothetical protein SACE_2245 1 None None None 134099976 Common - putative integral membrane protein SACE_3438 23 COG2339 COG2339, Predicted membrane protein Function unknown 134100964 Common - sulfatase SACE_4431 87 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 134102587 Common - 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase SACE_6150 180 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 134097797 Common - calcium-binding protein SACE_1207 67 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 134103793 Common leuS leucyl-tRNA synthetase SACE_7373 248 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 134100050 Common pcaB 3-carboxy-cis,cis-muconate cycloisomerase SACE_3512 159 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 134102721 Common atpE ATP synthase C chain SACE_6285 6 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 134096916 Common katA catalase SACE_0302 126 COG0753 KatE, Catalase Inorganic ion transport and metabolism 134101114 Common citE3 citrate lyase beta subunit SACE_4581 107 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 134098980 Common - putative signal-transduction protein with CBS domains SACE_2418 128 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 134096837 Nonpathogen - hypothetical protein SACE_0220 1 None None None 134103585 Common - HAD-superfamily hydrolase subfamily IA, variant 3 SACE_7163 59 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 134101780 Common pheS putative phenylalanyl-tRNA synthetase alpha subunit SACE_5277 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 134103599 Common - hypothetical protein SACE_7177 4 None None None 134102735 Common lysA diaminopimelate decarboxylase SACE_6299 218 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 134099107 Nonpathogen - hypothetical protein SACE_2552 1 None None None 134097767 Nonpathogen - hypothetical protein SACE_1176 1 None None None 134101054 Nonpathogen - hypothetical protein SACE_4521 3 COG3899 COG3899, Predicted ATPase General function prediction only 134100302 Common gabD3 succinate-semialdehyde dehydrogenase (NAD(P)+) SACE_3767 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 134102791 Common - hypothetical protein SACE_6357 6 COG3608 COG3608, Predicted deacylase General function prediction only 134098475 Common - low temperature requirement A SACE_1900 29 COG4292 COG4292, Predicted membrane protein Function unknown 134102135 Common rsbW anti-sigma factor SACE_5685 12 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 134098502 Nonpathogen - hypothetical protein SACE_1927 3 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 134102328 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase SACE_5881 200 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 134097622 Common - hypothetical protein SACE_1026 6 None None None 134103309 Nonpathogen - hypothetical protein SACE_6881 1 None None None 134099391 Common iclR repressor of aceBA operon SACE_2848 99 COG1414 IclR, Transcriptional regulator Transcription 134100404 Nonpathogen - hypothetical protein SACE_3869 1 None None None 134097206 Common - hypothetical protein SACE_0596 9 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134100044 Common - iron-sulfur cluster binding protein SACE_3506 94 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 134099544 Common - cyclase/dehydrase SACE_3002 9 COG3832 COG3832, Uncharacterized conserved protein Function unknown 134096858 Nonpathogen - hypothetical protein SACE_0241 2 None None None 134098464 Common - putative conserved alanine rich lipoprotein LppW SACE_1888 7 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 134097061 Common - hypothetical protein SACE_0448 30 None None None 134102233 Nonpathogen - hypothetical protein SACE_5785 1 None None None 134097491 Common - hypothetical protein SACE_0893 12 None None None 134101030 Common - probable methenyltetrahydrofolate cyclohydrolase SACE_4497 19 COG3404 COG3404, Methenyl tetrahydrofolate cyclohydrolase Amino acid transport and metabolism 134096779 Common - hypothetical protein SACE_0162 29 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 134101334 Common - short-chain dehydrogenase/reductase SDR SACE_4805 231 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134099319 Common - alpha/beta hydrolase domain protein SACE_2774 29 COG0657 Aes, Esterase/lipase Lipid metabolism 134102985 Nonpathogen - hypothetical protein SACE_6553 1 None None None 134099454 Common - integral membrane protein SACE_2912 19 COG2261 COG2261, Predicted membrane protein Function unknown 134103550 Common - ToxA protein SACE_7128 136 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 134101459 Common - acyl-CoA dehydrogenase, type 2-like SACE_4929 123 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134102242 Common - transcriptional regulator, GntR family SACE_5794 127 COG1802 GntR, Transcriptional regulators Transcription 134103096 Common - hypothetical protein SACE_6666 7 None None None 134099404 Common - similar to coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase SACE_2862 4 COG3945 COG3945, Uncharacterized conserved protein Function unknown 134100915 Common catA1 catechol 1,2-dioxygenase SACE_4382 55 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 134101464 Common - AraC family transcriptional regulator SACE_4934 116 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 134100542 Common - glutaconate CoA-transferase SACE_4007 99 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 134099652 Nonpathogen - hypothetical protein SACE_3110 2 COG3401 COG3401, Fibronectin type 3 domain-containing protein General function prediction only 134101867 Common - hypothetical protein SACE_5365 12 None None None 134099370 Common - Transposase SACE_2827 33 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 134103492 Common aroH chorismate mutase SACE_7067 14 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 134097472 Common - type I restriction-modification system methyltransferase subunit SACE_0871 159 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 134096763 Common - two-component system sensor kinase SACE_0145 144 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 134101284 Nonpathogen - hypothetical protein SACE_4752 1 None None None 134100793 Common lldP,lctP L-lactate permease SACE_4260 102 COG1620 LldP, L-lactate permease Energy production and conversion 134099890 Common - ribosomal pseudouridine synthase SACE_3351 204 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 134097835 Common - major facilitator superfamily MFS_1 SACE_1246 18 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 134098949 Common - possible ATP-dependent protease SACE_2385 86 COG0714 COG0714, MoxR-like ATPases General function prediction only 134097801 Nonpathogen - hypothetical protein SACE_1211 1 None None None 134101235 Common phzF phenazine biosynthesis protein SACE_4703 72 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 134100635 Common bglA beta-glucosidase SACE_4101 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 134099688 Common hcaC2 3-phenylpropionate dioxygenase ferredoxin subunit SACE_3146 85 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 134099018 Common - hypothetical protein SACE_2456 16 None None None 134102509 Common acyP acylphosphatase SACE_6072 49 COG1254 AcyP, Acylphosphatases Energy production and conversion 134097517 Common uppS1 putative undecaprenyl pyrophosphate synthetase SACE_0919 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 134100954 Nonpathogen - hypothetical protein SACE_4421 1 None None None 134101729 Common csbB stress response protein, glycosyl transferase family 2 SACE_5225 210 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 134099773 Common rbsK sugar kinase in PfkB family SACE_3234 118 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 134098312 Common lhr putative ATP-dependent DNA helicase SACE_1730 161 COG1201 Lhr, Lhr-like helicases General function prediction only 134100912 Common benA benzoate 1,2-dioxygenase alpha subunit SACE_4379 81 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 134102384 Common - glyoxalase/bleomycin resistance protein/dioxygenase SACE_5937 19 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 134098793 Common - glycine betaine transport system permease protein SACE_2224 135 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 134101654 Common - glyoxalase/bleomycin resistance protein/dioxygenase SACE_5145 26 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 134101765 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein SACE_5261 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 134101305 Common - hypothetical protein SACE_4773 25 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 134100909 Common - transcriptional regulator, LuxR family SACE_4376 25 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134103758 Common - zinc-binding oxidoreductase SACE_7338 158 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 134102045 Common - methyltransferase SACE_5595 51 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 134097999 Nonpathogen - hypothetical protein SACE_1413 3 None None None 134098816 Common - aldo/keto reductase SACE_2247 60 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 134097175 Common moaC molybdenum cofactor biosynthesis protein SACE_0564 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 134103703 Nonpathogen - hypothetical protein SACE_7281 1 None None None 134099952 Nonpathogen - hypothetical protein SACE_3413 1 None None None 134098052 Nonpathogen - TetR-family transcriptional regulator SACE_1466 2 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 134099061 Nonpathogen - hypothetical protein SACE_2504 1 None None None 134097040 Common - integral membrane protein SACE_0427 8 COG1289 COG1289, Predicted membrane protein Function unknown 134098022 Common - competence protein SACE_1436 138 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 134098231 Common - thiamineS protein SACE_1648 29 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 134096646 Common - acetyl-CoA carboxylase SACE_0028 228 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 134096961 Common - acetyltransferase SACE_0347 7 None None None 134097936 Common rpi ribose-5-phosphate isomerase B SACE_1349 126 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 134098034 Common - transcriptional regulator, XRE family SACE_1448 43 COG3800 COG3800, Predicted transcriptional regulator General function prediction only 134098387 Common - hypothetical protein SACE_1808 19 None None None 134101101 Common - hypothetical protein SACE_4568 5 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134102003 Common - hypothetical protein SACE_5553 8 None None None 134096770 Common pgmB 2,3-PDG dependent phosphoglycerate mutase SACE_0153 43 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 134101384 Common - amine oxidase, flavin-containing SACE_4854 36 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 134097074 Common - probable trehalose-phosphatase/glycoside hydrolase SACE_0461 103 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 134100982 Common exaA probable quinoprotein ethanol dehydrogenase precursor SACE_4449 60 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 134103372 Common hemC porphobilinogen deaminase SACE_6945 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 134101895 Common - long-chain-fatty-acid--CoA ligase SACE_5393 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134097413 Common - putative ABC transporter ATP-binding subunit SACE_0808 246 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 134097726 Nonpathogen - hypothetical protein SACE_1131 1 None None None 134101107 Common pteA1 modular polyketide synthase SACE_4574 209 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134098225 Common pepB leucyl aminopeptidase SACE_1642 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 134098251 Common aglA alpha-glucosidase SACE_1668 162 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 134102504 Common anmK anhydro-N-acetylmuramic acid kinase SACE_6067 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 134098297 Common metF 5,10-methylenetetrahydrofolate reductase SACE_1715 163 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 134100586 Common - peptidase C56, PfpI SACE_4051 142 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 134100989 Nonpathogen - hypothetical protein SACE_4456 1 None None None 134098422 Nonpathogen - hypothetical protein SACE_1846 1 None None None 134097944 Common - hypothetical protein SACE_1358 19 COG4759 COG4759, Uncharacterized protein conserved in bacteria containing thioredoxin-like domain Posttranslational modification, protein turnover, chaperones 134098997 Common - UspA domain protein SACE_2435 11 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 134102249 Common nadC nicotinate-nucleotide pyrophosphorylase SACE_5801 201 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 134099574 Common - LysR-family transcriptional regulator SACE_3032 178 COG0583 LysR, Transcriptional regulator Transcription 134101617 Common - CRISPR-associated protein Cas1/Cas4 SACE_5100 99 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 134096777 Common - transcriptional regulator, Cro/CI family SACE_0160 56 COG1396 HipB, Predicted transcriptional regulators Transcription 134103506 Nonpathogen - hypothetical protein SACE_7082 1 None None None 134096744 Common glpQ1 glycerophosphoryl diester phosphodiesterase SACE_0126 173 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 134102949 Common - transcriptional regulator, DeoR family SACE_6516 112 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 134097267 Common glpD glycerol-3-phosphate dehydrogenase SACE_0658 129 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 134097563 Common gvpK gas vesicle synthesis protein SACE_0967 21 None None None 134101546 Common - regulator SACE_5022 43 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 134101777 Common - hydrolase SACE_5274 8 COG5640 COG5640, Secreted trypsin-like serine protease Posttranslational modification, protein turnover, chaperones 134097830 Common - hypothetical protein SACE_1241 12 COG2140 COG2140, Thermophilic glucose-6-phosphate isomerase and related metalloenzymes Carbohydrate transport and metabolism / General function prediction only 134101606 Nonpathogen - hypothetical protein SACE_5085 1 None None None 134102593 Common - hypothetical protein SACE_6156 6 None None None 134099333 Common - monooxygenase, NtaA/SnaA/SoxA family SACE_2788 74 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 134099825 Common yurI extracellular ribonuclease SACE_3286 21 COG2356 EndA, Endonuclease I DNA replication, recombination, and repair 134102363 Common - hypothetical protein SACE_5916 6 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 134100415 Common aldH aldehyde dehydrogenase SACE_3880 217 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 134096790 Common - putative dioxygenase SACE_0173 36 COG3670 COG3670, Lignostilbene-alpha,beta-dioxygenase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 134099585 Nonpathogen - hypothetical protein SACE_3043 1 None None None 134098395 Nonpathogen - hypothetical protein SACE_1816 1 None None None 134102072 Common ctpD putative cation-transporting P-type ATPase D SACE_5622 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 134102681 Common - hypothetical protein SACE_6244 14 None None None 134099578 Common - MbtH protein SACE_3036 36 COG3251 COG3251, Uncharacterized protein conserved in bacteria Function unknown 134097977 Common - alcohol dehydrogenase, zinc-binding domain protein SACE_1391 204 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 134103603 Common - YCII-related protein SACE_7181 25 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 134099117 Common tnp9B transposase, IS4 family SACE_2562 30 None None None 134098608 Common - YibE/F-like protein SACE_2034 27 COG5438 COG5438, Predicted multitransmembrane protein Function unknown 134097213 Common - hypothetical protein SACE_0603 213 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134098042 Common mmsA2 methylmalonate-semialdehyde dehydrogenase (acylating) SACE_1456 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 134097762 Common sdhA succinate dehydrogenase flavoprotein subunit SACE_1170 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 134097775 Nonpathogen - hypothetical protein SACE_1185 1 None None None 134097915 Common - putative transposon tn5714 transposase SACE_1328 61 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134100406 Common - dTDP-glucose 4,6-dehydratase SACE_3871 60 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 134103052 Nonpathogen - hypothetical protein SACE_6622 1 None None None 134103813 Common - single-stranded nucleic acid binding R3H SACE_7393 44 COG1847 Jag, Predicted RNA-binding protein General function prediction only 134102589 Common - possible transcriptional regulator, ArsR family SACE_6152 41 COG0640 ArsR, Predicted transcriptional regulators Transcription 134097185 Nonpathogen - hypothetical protein SACE_0575 1 None None None 134099133 Nonpathogen - hypothetical protein SACE_2578 4 None None None 134100166 Nonpathogen - acetyltransferase-like SACE_3628 8 COG0456 RimI, Acetyltransferases General function prediction only 134097705 Common - hypothetical protein SACE_1109 27 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 134099711 Common - hypothetical protein SACE_3171 3 None None None 134101536 Nonpathogen - hypothetical protein SACE_5008 8 None None None 134098222 Common dldH2 dihydrolipoamide dehydrogenase SACE_1639 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 134098399 Common - transcriptional regulator SACE_1820 184 COG0583 LysR, Transcriptional regulator Transcription 134100900 Common - methyltransferase type 12 SACE_4367 50 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134096890 Nonpathogen - hypothetical protein SACE_0276 1 None None None 134101856 Common - anthranilate synthase component II SACE_5354 120 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 134102983 Common - phosphate binding protein (secreted protein) SACE_6551 4 None None None 134103547 Common purF amidophosphoribosyltransferase SACE_7125 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 134099252 Common - ATP-dependent DNA ligase SACE_2706 71 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 134103144 Common groEL1 60 kD chaperonin cpn60 SACE_6714 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 134102744 Common - dienelactone hydrolase SACE_6309 28 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 134098517 Nonpathogen - hypothetical protein SACE_1942 1 None None None 134103457 Common int integrase (recombinase) SACE_7032 46 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 134097756 Common - hypothetical protein SACE_1164 10 None None None 134100728 Common - putative anti-sigma regulatory factor,serine/threonine protein kinase SACE_4195 5 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 134101789 Common - putative two-component system response regulator SACE_5286 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 134102793 Common - flavin-binding monooxygenase-like protein SACE_6359 81 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 134101986 Common - putative sporulation and cell division regulator protein SACE_5535 8 None None None 134103258 Common rpsC 30S ribosomal protein S3 SACE_6830 235 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 134103030 Nonpathogen - hypothetical protein SACE_6599 23 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 134098595 Common rubC crossover junction endodeoxyribonuclease RuvC SACE_2021 187 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 134098454 Common - hypothetical protein SACE_1878 5 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 134100393 Common - dicarboxylate carrier MatC domain protein SACE_3858 18 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 134100707 Common - methyltransferase SACE_4174 25 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 134102830 Common - alcohol dehydrogenase, zinc-binding SACE_6396 208 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 134102813 Common - DNA-binding protein SACE_6379 19 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 134097554 Common - two-component system sensor kinase SACE_0957 96 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 134098800 Common - hypothetical protein SACE_2231 21 COG2411 COG2411, Uncharacterized conserved protein Function unknown 134096785 Common - phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase SACE_0168 61 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 134098353 Common - hypothetical protein SACE_1772 14 COG1409 Icc, Predicted phosphohydrolases General function prediction only 134098729 Common tal transaldolase SACE_2159 136 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 134101823 Nonpathogen - hypothetical protein SACE_5320 1 None None None 134098304 Nonpathogen - hypothetical protein SACE_1722 4 None None None 134103045 Common - putative serine/threonine protein kinase SACE_6615 144 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 134097092 Nonpathogen - hypothetical protein SACE_0478 1 None None None 134097100 Common ectD ectoine hydroxylase SACE_0486 31 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 134102688 Common - hypothetical protein SACE_6251 6 None None None 134097808 Common poxB pyruvate dehydrogenase SACE_1218 220 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 134099875 Common - hypothetical protein SACE_3336 52 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 134102705 Common - putative ABC transporter amino acid-binding protein SACE_6269 100 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 134103527 Common trxA4 thioredoxin SACE_7104 10 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 134101353 Common - ABC peptide transporter binding protein SACE_4824 173 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 134100278 Nonpathogen - integral membrane protein SACE_3743 1 None None None 134098987 Common - universal stress protein SACE_2425 24 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 134099066 Common - aminotransferase, class I SACE_2509 228 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 134102311 Common pcaR transcriptional regulator, IclR family SACE_5863 113 COG1414 IclR, Transcriptional regulator Transcription 134101337 Common - penicillin-binding protein SACE_4808 103 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 134103276 Nonpathogen - hypothetical protein SACE_6848 1 None None None 134101803 Nonpathogen - hypothetical protein SACE_5300 2 None None None 134098170 Common - putative bifunctional protein (ribonuclease H/phosphoglycerate mutase) SACE_1584 159 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 134101851 Common - endonuclease/exonuclease/phosphatase family SACE_5349 5 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 134097449 Common dppA1 probable oligopeptide binding protein of ABC transporter SACE_0844 177 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 134099375 Common - two-component system sensor kinase SACE_2832 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 134101707 Nonpathogen - hypothetical protein SACE_5201 1 None None None 134097734 Nonpathogen - hypothetical protein SACE_1139 2 None None None 134102426 Nonpathogen - hypothetical protein SACE_5982 1 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 134103288 Common mce4D MCE family protein SACE_6860 17 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 134102054 Common - TetR-family transcriptional regulator SACE_5604 67 COG1309 AcrR, Transcriptional regulator Transcription 134100400 Common - protein of unknown function DUF849 SACE_3865 62 COG3246 COG3246, Uncharacterized conserved protein Function unknown 134099622 Common - oxidoreductase, aldo/keto reductase family SACE_3080 196 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 134098941 Common thcA aldehyde dehydrogenase (NAD+) SACE_2377 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 134097241 Nonpathogen - hypothetical protein SACE_0631 1 None None None 134102600 Nonpathogen - hypothetical protein SACE_6163 3 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134102156 Common leuA2 2-isopropylmalate synthase SACE_5707 211 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 134103383 Nonpathogen - hypothetical protein SACE_6957 1 None None None 134097299 Common cvnC6 hypothetical protein SACE_0692 9 None None None 134101687 Common ssuD1 alkanesulfonate monooxygenase SACE_5179 85 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 134097021 Common - putative Bordetella pertussis Bvg accessory factor family SACE_0408 132 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 134099708 Common - 3-demethylubiquinone-9 3-methyltransferase SACE_3168 66 COG3865 COG3865, Uncharacterized protein conserved in bacteria Function unknown 134100676 Common - cytochrome P450 monooxygenase SACE_4143 68 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134100133 Nonpathogen - PE-PGRS family protein SACE_3595 1 None None None 134102334 Common lldD2 L-lactate dehydrogenase SACE_5887 114 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 134101904 Common - putative dehydrogenase/oxygenase subunit (flavoprotein) SACE_5403 19 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 134099511 Common - PAS:GGDEF SACE_2969 191 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 134099437 Common - betaine-aldehyde dehydrogenase SACE_2895 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 134102806 Common - putative long chain fatty acid coA ligase SACE_6372 195 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 134099733 Common - ABC-type antimicrobial peptide transport system,ATPase component SACE_3194 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 134099793 Common - amino acid permease-associated region SACE_3254 63 None None None 134097198 Nonpathogen - hypothetical protein SACE_0588 2 None None None 134100757 Nonpathogen tagC,dinC teichoic acid biosynthesis protein C SACE_4224 2 COG4263 NosZ, Nitrous oxide reductase Energy production and conversion 134102301 Common murD UDP-N-acetylmuramoylalanine--D-glutamate ligase SACE_5853 206 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 134098109 Common fabF 3-oxoacyl-[acyl-carrier-protein] synthase SACE_1523 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134102691 Common fabG 3-oxoacyl-[acyl-carrier-protein] reductase SACE_6255 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134102646 Common cdo2 cysteine dioxygenase SACE_6209 7 None None None 134099605 Nonpathogen - nitrogen-fixing NifU-like SACE_3063 3 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 134096665 Common ftsW2 putative cell division protein SACE_0047 200 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 134097594 Common - probable two-component sensor kinase SACE_0998 204 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 134103137 Common guaB3 inositol-5-monophosphate dehydrogenase SACE_6707 233 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 134103434 Common - transcriptional regulator, XRE family SACE_7009 5 None None None 134103774 Common - possible membrane protein SACE_7354 12 COG5650 COG5650, Predicted integral membrane protein Function unknown 134096877 Common - hypothetical protein SACE_0262 2 None None None 134098383 Common - probable secreted alanine rich protein SACE_1804 4 None None None 134103295 Common rplL 50S ribosomal protein L7/L12 SACE_6867 215 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 134100462 Common korA 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit SACE_3927 106 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 134096920 Common bga beta-galactosidase SACE_0306 25 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 134102325 Common - phage shock protein A, PspA SACE_5878 17 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 134097105 Nonpathogen - hypothetical protein SACE_0492 1 None None None 134097134 Common moaA3 molybdopterin biosynthesis protein MoeA SACE_0523 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 134101420 Common - MFS transporter, DHA1 family SACE_4890 112 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134097811 Common - membrane-flanked domain protein SACE_1221 20 COG3428 COG3428, Predicted membrane protein Function unknown 134103125 Common - two-component system sensor kinase SACE_6695 40 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 134098666 Nonpathogen - hypothetical protein SACE_2095 1 None None None 134098868 Nonpathogen - hypothetical protein SACE_2302 1 None None None 134099070 Nonpathogen - hypothetical protein SACE_2513 1 None None None 134099149 Common - hypothetical protein SACE_2594 64 COG1434 COG1434, Uncharacterized conserved protein Function unknown 134103138 Common - inosine-5'-monophosphate dehydrogenase SACE_6708 241 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 134102216 Common - two-component system sensor kinase SACE_5767 207 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 134103257 Common rplP 50S ribosomal protein L16 SACE_6829 217 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 134097969 Common - oxidoreductase alpha (molybdopterin) subunit SACE_1383 181 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 134097290 Nonpathogen - hypothetical protein SACE_0683 1 None None None 134103078 Common - bifunctional deaminase-reductase-like protein SACE_6648 68 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 134101123 Common - amylo-alpha-1,6-glucosidase SACE_4590 45 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 134096753 Common - hypothetical protein SACE_0135 11 None None None 134099851 Common - two-component system response regulator SACE_3312 103 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134096956 Common - mandelate racemase/muconate lactonizing enzyme SACE_0342 55 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 134103306 Common - hypothetical protein SACE_6878 171 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 134103732 Nonpathogen - hypothetical protein SACE_7310 1 None None None 134100532 Common - glutamate synthase, NADH/NADPH, small subunit 1 SACE_3997 203 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 134096903 Common - transposase, IS891/IS1136/IS1341 SACE_0289 71 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 134100158 Common - hypothetical protein SACE_3620 6 None None None 134103564 Common purL phosphoribosylformylglycinamidine synthase II SACE_7142 234 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 134100146 Common gcn3 methylthioribose-1-phosphate isomerase SACE_3608 130 COG0182 COG0182, Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 134098522 Common - luciferase-like SACE_1947 46 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 134097066 Common - ABC-type transporter SACE_0453 31 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 134102903 Common manB mannose-1-phosphate guanyltransferase SACE_6470 233 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 134102697 Common - LacI-type transcriptional regulator SACE_6261 126 COG1609 PurR, Transcriptional regulators Transcription 134101812 Common cyp20 putative cytochrome P450 SACE_5309 75 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134101993 Common pdhB1 pyruvate dehydrogenase E1 component beta subunit SACE_5543 205 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 134103398 Common - putative MFS sugar transporter protein SACE_6972 40 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 134103126 Common - hypothetical protein SACE_6696 8 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 134099942 Common gatA amidase SACE_3403 220 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 134101797 Nonpathogen - hypothetical protein SACE_5294 1 None None None 134100477 Common fahA putative fumarylacetoacetase SACE_3942 56 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 134102948 Common - glycerol-3-phosphate dehydrogenase SACE_6515 149 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 134099722 Common - hypothetical protein SACE_3182 12 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 134101408 Common - putative alkanesulfonate monooxygenase SACE_4878 90 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 134099182 Nonpathogen - hypothetical protein SACE_2634 1 None None None 134102599 Common - hypothetical protein SACE_6162 8 COG2259 COG2259, Predicted membrane protein Function unknown 134100513 Common - cyclic nucleotide-binding domain (cNMP-BD) protein SACE_3978 27 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 134101362 Common - hypothetical protein SACE_4833 15 None None None 134103638 Common - transcriptional regulator, TetR family SACE_7216 31 COG1309 AcrR, Transcriptional regulator Transcription 134102178 Common - hypothetical protein SACE_5729 14 COG3953 COG3953, SLT domain proteins General function prediction only 134097602 Common - extracellular solute-binding protein, family 5 SACE_1006 122 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 134097451 Common - ABC peptide transporter, permease component SACE_0846 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 134100709 Common - short chain dehydrogenase SACE_4176 151 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 134100995 Common - putative transcription antitermination regulator SACE_4462 10 None None None 134098477 Common fadB2 3-hydroxybutyryl-CoA dehydrogenase SACE_1902 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 134100836 Common - hypothetical protein SACE_4303 2 None None None 134100658 Common fadE1 acyl-CoA dehydrogenase SACE_4125 140 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134096654 Common - hypothetical protein SACE_0036 3 None None None 134098657 Common padI phenylacrylic acid decarboxylase-like protein SACE_2086 151 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 134098711 Common whiA sporulation regulatory protein SACE_2141 46 COG1481 COG1481, Uncharacterized protein conserved in bacteria Function unknown 134100626 Nonpathogen - hypothetical protein SACE_4091 1 None None None 134102839 Common - allantoate amidohydrolase SACE_6405 84 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 134103375 Common - glutaredoxin 2 SACE_6949 21 None None None 134097479 Nonpathogen - hypothetical protein SACE_0881 1 None None None 134101517 Common - hypothetical protein SACE_4989 9 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 134102952 Nonpathogen - PE-PGRS family protein SACE_6519 1 COG4907 COG4907, Predicted membrane protein Function unknown 134103723 Common - transcriptional regulator (TetR/AcrR family) SACE_7301 109 COG1309 AcrR, Transcriptional regulator Transcription 134099464 Common - cytochrome P450 hydroxylase SACE_2922 77 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134097586 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit SACE_0990 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 134103693 Nonpathogen - hypothetical protein SACE_7271 1 None None None 134100579 Nonpathogen - hypothetical protein SACE_4044 1 None None None 134103059 Common spaF ABC transporter, ATP-binding protein SACE_6629 247 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 134096659 Common - transposase for IS3518 SACE_0041 143 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 134098935 Common tnp9B transposase, IS4 family SACE_2371 23 None None None 134101880 Common - HAD-superfamily hydrolase subfamily IA, variant 3 SACE_5378 75 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 134103525 Common - hydrolase SACE_7102 24 COG0429 COG0429, Predicted hydrolase of the alpha/beta-hydrolase fold General function prediction only 134103067 Common - membrane-bound metal-dependent hydrolase SACE_6637 10 None None None 134102994 Common fdhA glutathione-independent formaldehyde dehydrogenase SACE_6562 205 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 134102015 Common rkpK UDP-glucose 6-dehydrogenase protein SACE_5565 205 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 134098839 Common - potential 5'-3' exonuclease SACE_2270 216 COG0258 Exo, 5'-3' exonuclease (including N-terminal domain of PolI) DNA replication, recombination, and repair 134103217 Common - transcriptional regulator, XRE family SACE_6788 6 None None None 134103250 Common rpsH 30S ribosomal protein S8 SACE_6822 244 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 134099789 Common - pyridine nucleotide-disulphide oxidoreductase SACE_3250 69 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 134103640 Common - hypothetical protein SACE_7218 4 None None None 134097546 Common - L-fucose isomerase, putative SACE_0948 22 COG2407 FucI, L-fucose isomerase and related proteins Carbohydrate transport and metabolism 134097987 Common ndk nucleoside diphosphate kinase SACE_1401 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 134103260 Common rpsS 30S ribosomal protein S19 SACE_6832 239 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 134103530 Common - hypothetical protein SACE_7107 10 None None None 134096986 Common - DEAD/DEAH box helicase-like SACE_0373 185 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 134099196 Common slpD proteinase (secreted protein) SACE_2649 36 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134101170 Common - Hypothetical Cytosolic Protein SACE_4637 21 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 134102187 Nonpathogen - hypothetical protein SACE_5738 1 None None None 134099181 Common - conserved hypothetical protein-putative NAD-dependent aldehyde dehydrogenase/putative phenazine antibiotic biosynthesis protein SACE_2633 10 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 134102844 Common - amino acid ABC transporter, permease protein SACE_6410 90 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 134100046 Common - transcriptional regulator, GntR family SACE_3508 99 COG2186 FadR, Transcriptional regulators Transcription 134099486 Common - Zn-dependent alcohol dehydrogenase SACE_2944 128 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 134103615 Nonpathogen - hypothetical protein SACE_7193 3 None None None 134101024 Common soxG sarcosine oxidase gamma subunit SACE_4491 30 COG4583 COG4583, Sarcosine oxidase gamma subunit Amino acid transport and metabolism 134100417 Common gdhA1 glutamate dehydrogenase (NAD(P)+) SACE_3882 180 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 134098382 Common suhB putative myo-inositol-1(or 4)-monophosphatase SACE_1803 190 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 134101700 Common iolG putative oxidoreductase myo-inositol 2-dehydrogenase SACE_5193 157 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 134098014 Common nadD putative nicotinate-nucleotide adenylyltransferase SACE_1428 186 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 134099008 Common - UspA domain protein SACE_2446 106 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 134103191 Common - DedA family protein SACE_6761 21 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 134098011 Common - transcriptional regulator, TetR family SACE_1425 19 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 134098512 Common gltP1 sodium:dicarboxylate symporter: DAACS family SACE_1937 160 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 134099918 Common - two component system response regulator SACE_3379 169 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134099884 Common galE UDP-glucose 4-epimerase SACE_3345 231 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 134098807 Common hisG ATP phosphoribosyltransferase SACE_2238 212 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 134099387 Common - TPR repeat SACE_2844 8 None None None 134098625 Common aroE shikimate 5-dehydrogenase SACE_2055 172 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 134100616 Common - probable beta lactamase SACE_4081 70 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 134097326 Common eryBIV dTDP-4-keto-6-deoxy-L-hexose 4-reductase SACE_0720 74 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 134097675 Nonpathogen - hypothetical protein SACE_1079 1 None None None 134102817 Common - hypothetical protein SACE_6383 9 None None None 134100182 Common thrS2 putative threonyl-tRNA synthetase SACE_3644 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 134098788 Nonpathogen - hypothetical protein SACE_2219 1 None None None 134102920 Nonpathogen - hypothetical protein SACE_6487 2 None None None 134100711 Nonpathogen - hypothetical protein SACE_4178 2 None None None 134097369 Common - DeoR-family transcriptional regulator SACE_0763 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 134096691 Common - probable copper resistance protein SACE_0073 28 COG2372 CopC, Uncharacterized protein, homolog of Cu resistance protein CopC General function prediction only 134096781 Common - hypothetical protein SACE_0164 12 COG5650 COG5650, Predicted integral membrane protein Function unknown 134103406 Common - hypothetical protein SACE_6980 14 None None None 134103281 Common - DNA-directed RNA polymerase subunit beta' SACE_6853 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 134100488 Common pdhB1 pyruvate dehydrogenase E1 component beta subunit SACE_3953 196 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 134101515 Common - hypothetical protein SACE_4987 4 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 134100096 Common - 6-phosphogluconate dehydrogenase, NAD-binding SACE_3558 160 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 134101059 Common - hydantoinase/oxoprolinase SACE_4526 101 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134099895 Common - carbohydrate kinase, thermoresistant glucokinase SACE_3356 82 COG3265 GntK, Gluconate kinase Carbohydrate transport and metabolism 134103317 Common nuoN NADH dehydrogenase subunit N SACE_6889 208 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 134101961 Common - hypothetical protein SACE_5463 7 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 134098432 Nonpathogen ard phosphotransferase (aminonucleoside antibiotic resistance) SACE_1856 6 COG1936 COG1936, Predicted nucleotide kinase (related to CMP and AMP kinases) Nucleotide transport and metabolism 134098969 Common phdB probable pyruvate dehydrogenase E1 component,alpha subunit SACE_2407 155 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 134100698 Common - secreted trypsin-like serine protease SACE_4165 32 COG5640 COG5640, Secreted trypsin-like serine protease Posttranslational modification, protein turnover, chaperones 134101052 Common - alcohol dehydrogenase GroES-like SACE_4519 192 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 134102483 Common - hypothetical protein SACE_6046 17 None None None 134103018 Common - putative penicillin-binding protein SACE_6587 151 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 134099911 Common - hypothetical protein SACE_3372 2 None None None 134099470 Nonpathogen - hypothetical protein SACE_2928 1 None None None 134103234 Common rpsM 30S ribosomal protein S13 SACE_6806 241 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 134099428 Common - serine/threonine kinase SACE_2886 99 COG1262 COG1262, Uncharacterized conserved protein Function unknown 134101315 Common - secretory lipase family protein SACE_4783 19 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 134100687 Common - NAD-dependent epimerase/dehydratase SACE_4154 89 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 134103006 Common - hypothetical protein SACE_6574 51 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 134102022 Common - glycosyl transferase, group 1 SACE_5572 15 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 134098260 Common asn1 asparagine synthase (glutamine-hydrolyzing) SACE_1677 150 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 134100640 Common iolF inositol transport protein SACE_4106 70 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134097406 Common tatD putative deoxyribonuclease SACE_0800 236 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 134099928 Common - putative cytosine/uracil/thiamine/allantoin permeases SACE_3389 59 COG1953 FUI1, Cytosine/uracil/thiamine/allantoin permeases Nucleotide transport and metabolism / Coenzyme metabolism 134099650 Nonpathogen - hypothetical protein SACE_3108 2 None None None 134100505 Common - cation efflux system protein SACE_3970 184 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 134098908 Common - putative acyl carrier protein SACE_2344 4 None None None 134103088 Nonpathogen - hypothetical protein SACE_6658 1 None None None 134100565 Common - transglycosylase-associated protein SACE_4030 15 COG2261 COG2261, Predicted membrane protein Function unknown 134098859 Common - putative integral membrane protein SACE_2291 68 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 134097044 Common - hypothetical protein SACE_0431 7 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 134097748 Common - permease, MDR related, probably tetracycline resistance protein SACE_1156 11 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134103800 Common - uncharacterized membrane protein, virulence factor homolog SACE_7380 187 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 134103805 Common trxB thioredoxin reductase SACE_7385 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 134098413 Common hemG protoporphyrinogen oxidase SACE_1837 42 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 134096882 Common - hypothetical protein SACE_0267 5 None None None 134099380 Common - hypothetical protein SACE_2837 4 None None None 134099560 Common phaB enoyl-CoA hydratase/isomerase SACE_3018 153 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 134100815 Common cysK3 putative cysteine synthase SACE_4282 219 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 134102316 Common moxR1 methanol dehydrogenase regulatory protein SACE_5869 175 COG0714 COG0714, MoxR-like ATPases General function prediction only 134103049 Common - transcriptional regulator SACE_6619 25 COG1733 COG1733, Predicted transcriptional regulators Transcription 134102345 Common - putative hydrolase of the metallo-beta-lactamase superfamily SACE_5898 162 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 134100974 Common - steroid delta-isomerase SACE_4441 10 None None None 134100856 Common - oxidoreductase, short-chain dehydrogenase/reductase family SACE_4323 136 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 134103784 Common - protein of unknown function UPF0118 SACE_7364 16 COG0628 PerM, Predicted permease General function prediction only 134101525 Nonpathogen - hypothetical protein SACE_4997 1 None None None 134097470 Common - putative type I site-specific restriction-modification system (HsdR) SACE_0868 124 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 134100693 Common - ABC sugar transporter, permease component SACE_4160 143 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 134101293 Common - hypothetical protein SACE_4761 4 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 134097878 Common - ErfK/YbiS/YcfS/YnhG SACE_1291 19 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 134099936 Nonpathogen - hypothetical protein SACE_3397 1 None None None 134097353 Nonpathogen - hypothetical protein SACE_0747 3 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 134100273 Common - hypothetical protein SACE_3738 12 COG5525 COG5525, Bacteriophage tail assembly protein General function prediction only 134099804 Common - secreted protein SACE_3265 24 None None None 134102168 Common tesB acyl-CoA thioesterase II SACE_5719 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 134099956 Common - hydrolase SACE_3417 179 COG0388 COG0388, Predicted amidohydrolase General function prediction only 134102459 Common - regulatory protein SACE_6021 15 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 134102261 Common - integral membrane efflux protein SACE_5813 172 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134099040 Nonpathogen - hypothetical protein SACE_2480 1 None None None 134100806 Nonpathogen - hypothetical protein SACE_4273 1 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 134098084 Common - ferric uptake regulation protein SACE_1498 191 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 134100895 Common - pectate lyase SACE_4362 13 None None None 134100979 Common pqqC pyrroloquinoline quinone biosynthesis protein PqqC SACE_4446 38 COG5424 COG5424, Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C Coenzyme metabolism 134096676 Common - putative acetyltransferase SACE_0058 45 COG2162 NhoA, Arylamine N-acetyltransferase Secondary metabolites biosynthesis, transport, and catabolism 134097224 Nonpathogen - hypothetical protein SACE_0614 4 None None None 134100389 Common dhbC isochorismate synthase DhbC SACE_3854 221 COG1169 MenF, Isochorismate synthase Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism 134103480 Nonpathogen - hypothetical protein SACE_7055 1 None None None 134101523 Common - hypothetical protein SACE_4995 19 COG4639 COG4639, Predicted kinase General function prediction only 134102496 Common - hypothetical protein SACE_6059 5 COG0645 COG0645, Predicted kinase General function prediction only 134100365 Common - di-tripeptide ABC transporter (permease) SACE_3830 79 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 134102131 Nonpathogen - hypothetical protein SACE_5681 1 None None None 134102757 Common - ABC transport protein membrane component SACE_6322 106 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 134098724 Common - transposase, IS891/IS1136/IS1341 SACE_2154 68 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 134102763 Common - putative pyridoxal-phosphate dependent enzyme SACE_6328 213 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 134098119 Common - hypothetical protein SACE_1533 16 None None None 134099049 Nonpathogen - hypothetical protein SACE_2492 1 COG5416 COG5416, Uncharacterized integral membrane protein Function unknown 134099729 Common - cytochrome P450 SACE_3189 19 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134102533 Common - integral membrane protein SACE_6096 17 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 134103694 Common - FAD linked oxidase-like SACE_7272 48 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 134099477 Common - alpha/beta hydrolase fold SACE_2935 31 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134098332 Common - hypothetical protein SACE_1750 29 None None None 134102183 Common - galactofuranosyl transferase SACE_5734 18 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 134099050 Common - secreted protein SACE_2493 218 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 134101419 Common - transcriptional regulator, TetR family SACE_4889 99 COG1309 AcrR, Transcriptional regulator Transcription 134102925 Common - inositol-phosphate phosphatase SACE_6492 177 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 134098561 Common - amino acid permease-associated region SACE_1987 109 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 134102592 Common serA D-3-phosphoglycerate dehydrogenase (PgdH) SACE_6155 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 134102442 Nonpathogen - hypothetical protein SACE_5998 1 None None None 134099057 Common - hypothetical protein SACE_2500 4 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 134103566 Common purS phosphoribosylformylglycinamidine synthase SACE_7144 97 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 134098670 Common gmk guanylate kinase SACE_2100 213 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 134097512 Common guaB2 inositol-5-monophosphate dehydrogenase SACE_0914 233 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 134097398 Common - tetrapyrrole methylase family protein SACE_0792 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 134103326 Common nuoE putative NADH dehydrogenase chain E SACE_6898 155 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 134101247 Common - secreted protein SACE_4715 13 COG4632 EpsL, Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Carbohydrate transport and metabolism 134102630 Common iroB putative glycosyl transferase, related to UDP-glucuronosyltransferase SACE_6193 45 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 134096822 Common - phytase SACE_0205 22 None None None 134099889 Nonpathogen - hypothetical protein SACE_3350 1 None None None 134099305 Common - glucose-methanol-choline oxidoreductase SACE_2760 92 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 134102864 Common sigR RNA polymerase sigma factor SACE_6430 172 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 134103656 Nonpathogen - hypothetical protein SACE_7234 1 None None None 134097125 Common def putative polypeptide deformylase SACE_0514 212 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 134099298 Common - transposase, IS605 OrfB family SACE_2753 68 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 134098753 Common - hypothetical protein SACE_2183 143 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 134103684 Common - response regulator, two-component system SACE_7262 182 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134099780 Common accD2 propionyl-CoA carboxylase, beta subunit SACE_3241 143 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 134102293 Common nos nitric oxide synthase oxygenase SACE_5845 11 COG4362 COG4362, Nitric oxide synthase, oxygenase domain Inorganic ion transport and metabolism / Amino acid transport and metabolism 134096810 Common - oxidoreductase, short-chain dehydrogenase/reductase family SACE_0193 169 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 134098137 Common alpH allophanate hydrolase SACE_1551 99 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 134098448 Common - ATP/GTP-binding integral membrane protein SACE_1872 83 COG1485 COG1485, Predicted ATPase General function prediction only 134099500 Common - hypothetical protein SACE_2958 11 None None None 134097154 Nonpathogen - transmembrane transport protein SACE_0543 3 None None None 134101374 Common - WD-40 repeat SACE_4845 45 COG2319 COG2319, FOG: WD40 repeat General function prediction only 134102935 Common celD glucan 1,4-beta-glucosidase precursor SACE_6502 113 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 134103290 Common mce5B putative Mce family protein SACE_6862 26 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 134096819 Common - probable cysteine desulfurase SACE_0202 172 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 134100675 Common - cytochrome P450 monooxygenase SACE_4142 70 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134100126 Common - possible lipoprotein SACE_3588 6 COG3391 COG3391, Uncharacterized conserved protein Function unknown 134103081 Common folD methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase SACE_6651 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 134098617 Common ychM sulfate transporter SACE_2047 161 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 134102899 Common - LPPG:FO 2-phopspho-L-lactate transferase SACE_6466 39 COG0391 COG0391, Uncharacterized conserved protein Function unknown 134096657 Nonpathogen - hypothetical protein SACE_0039 1 None None None 134097302 Common - protein of unknown function DUF574 SACE_0695 12 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 134097273 Common - transcriptional regulator, LacI-family SACE_0664 126 COG1609 PurR, Transcriptional regulators Transcription 134098374 Common - ribonuclease BN SACE_1794 9 COG1295 Rbn, Predicted membrane protein Function unknown 134099677 Common - short-chain dehydrogenase/reductase SDR SACE_3135 238 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 134100430 Common metF 5,10-methylenetetrahydrofolate reductase SACE_3895 152 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 134098427 Nonpathogen - hypothetical protein SACE_1851 1 None None None 134098243 Common - two component system response regulator SACE_1660 217 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134103610 Nonpathogen - hypothetical protein SACE_7188 1 None None None 134101436 Common - cyclic nucleotide-binding domain (cNMP-BD) protein SACE_4906 30 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 134102652 Common - hypothetical protein SACE_6215 6 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 134096669 Common - putative exported phosphatase SACE_0051 3 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 134101877 Nonpathogen - putative cyclase-dehydratase SACE_5375 2 None None None 134099099 Common proP proline/betaine transporter SACE_2544 49 None None None 134096714 Common ggt1 putative gamma-glutamyl transferase SACE_0096 147 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 134097229 Common sodF superoxide dismutase [Fe-Zn] 1 (FeSOD I) SACE_0619 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 134103304 Common - hypothetical protein SACE_6876 31 COG2030 MaoC, Acyl dehydratase Lipid metabolism 134096948 Common - putative membrane-associated serine protease SACE_0334 185 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 134101577 Common - amidohydrolase 2 SACE_5053 22 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 134101445 Nonpathogen - hypothetical protein SACE_4915 1 None None None 134098776 Common - 3-ketoacyl-(acyl-carrier-protein) reductase SACE_2206 233 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134100357 Common - hypothetical protein SACE_3822 12 None None None 134099713 Common - HAD-superfamily hydrolase subfamily IA, variant 3 SACE_3173 51 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 134096721 Nonpathogen - hypothetical protein SACE_0103 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 134101221 Common - transcriptional regulator, LysR family SACE_4689 169 COG0583 LysR, Transcriptional regulator Transcription 134102827 Common ssfR IclR-family transcriptional regulator SACE_6393 105 COG1414 IclR, Transcriptional regulator Transcription 134100768 Nonpathogen - hypothetical protein SACE_4235 1 None None None 134103559 Common - diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) SACE_7137 189 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 134101484 Common - integrase, catalytic region SACE_4954 22 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 134099247 Common - ABC transporter related SACE_2701 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 134097002 Common - probable transcriptional regulator, MarR family SACE_0389 63 COG1846 MarR, Transcriptional regulators Transcription 134097746 Common - DNA-binding protein SACE_1154 7 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 134097688 Common uvrD2 ATP-dependent DNA helicase SACE_1092 230 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 134102659 Nonpathogen - secreted protein SACE_6222 3 None None None 134096726 Nonpathogen - endo-1,4-beta-glucanase SACE_0108 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 134099731 Common pknD putative serine/threonine-protein kinase SACE_3192 155 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 134100025 Common - general substrate transporter SACE_3487 133 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134099160 Nonpathogen - hypothetical protein SACE_2610 3 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 134101775 Common - hypothetical protein SACE_5272 32 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 134097583 Nonpathogen - hypothetical protein SACE_0987 1 None None None 134096756 Nonpathogen - hypothetical protein SACE_0138 3 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 134098715 Common tpiA,tpi triosephosphate isomerase SACE_2145 218 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 134102322 Common end8 endonuclease VIII SACE_5875 147 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 134097953 Common - short-chain dehydrogenase/reductase SDR SACE_1367 216 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 134101191 Common iolT sugar transporter SACE_4658 158 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134097535 Common xseA putative exodeoxyribonuclease VII large subunit SACE_0937 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 134102137 Common mepA membrane proteins related to metalloendopeptidases SACE_5687 194 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 134096834 Common hisC2 putative histidinol-phosphate aminotransferase SACE_0217 239 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 134101359 Common - ABC transporter sugar permease SACE_4830 144 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 134096633 Common - acyl-CoA dehydrogenase SACE_0015 144 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134098921 Common yrbE4B putative ABC transport system permease protein SACE_2357 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 134099187 Common - transcriptional regulator, IclR family SACE_2639 119 COG1414 IclR, Transcriptional regulator Transcription 134099220 Nonpathogen - hypothetical protein SACE_2673 5 COG0456 RimI, Acetyltransferases General function prediction only 134099170 Common - cytochrome P450 CYP116 SACE_2622 82 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134100750 Nonpathogen - hypothetical protein SACE_4217 1 None None None 134096918 Common - transcriptional regulator, MarR family with acetyltransferase activity SACE_0304 31 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 134100662 Common - transcriptional regulator, TetR family SACE_4129 9 COG1309 AcrR, Transcriptional regulator Transcription 134099847 Common cypA cytochrome P450 SACE_3308 86 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134100194 Common pcrA ATP-dependent DNA helicase SACE_3656 237 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 134102279 Nonpathogen - possible membrane protein SACE_5831 2 None None None 134103469 Nonpathogen - membrane protein SACE_7044 6 None None None 134097720 Common ssb putative single-strand DNA-binding protein SACE_1125 155 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 134098885 Nonpathogen - hypothetical protein SACE_2320 1 None None None 134099490 Common - transcriptional regulator, TetR family SACE_2948 32 COG1309 AcrR, Transcriptional regulator Transcription 134097080 Nonpathogen - hypothetical protein SACE_0466 3 None None None 134102357 Nonpathogen - hypothetical protein SACE_5910 1 None None None 134102396 Common cbiD cobalt-precorrin-6A synthase SACE_5949 77 COG1903 CbiD, Cobalamin biosynthesis protein CbiD Coenzyme metabolism 134102282 Common - hypothetical protein SACE_5834 169 COG1496 COG1496, Uncharacterized conserved protein Function unknown 134103630 Common dnaJ molecular chaperone SACE_7208 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 134103588 Common - hypothetical protein SACE_7166 15 COG3953 COG3953, SLT domain proteins General function prediction only 134100186 Common - hypothetical protein SACE_3648 23 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134103271 Nonpathogen - hypothetical protein SACE_6843 4 None None None 134099861 Common - molybdopterin-binding oxidoreductase SACE_3322 97 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 134103795 Nonpathogen - hypothetical protein SACE_7375 1 None None None 134099021 Common - phosphoenolpyruvate synthase (pyruvate, water dikinase) SACE_2459 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 134100937 Common prpC3 magnesium or manganese-dependent protein phosphatase SACE_4404 130 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 134101918 Nonpathogen - hypothetical protein SACE_5418 1 COG3462 COG3462, Predicted membrane protein Function unknown 134099634 Common xdhB xanthine dehydrogenase FAD-binding subunit SACE_3092 57 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 134103247 Common rpsE 30S ribosomal protein S5 SACE_6819 247 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 134097552 Common alkA putative 3-methyladenine DNA glycosylase SACE_0955 95 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 134097896 Common - putative peptide monooxygenase SACE_1309 52 COG3486 IucD, Lysine/ornithine N-monooxygenase Secondary metabolites biosynthesis, transport, and catabolism 134102113 Common - hydrolase, Ama/HipO/HyuC family SACE_5663 89 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 134100861 Common - dimethylallyltranstransferase / geranyltranstransferase / geranylgeranyl pyrophosphate synthetase SACE_4328 240 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 134100997 Nonpathogen - hypothetical protein SACE_4464 1 None None None 134101769 Common argR arginine repressor (partial match) SACE_5265 78 COG1438 ArgR, Arginine repressor Transcription 134103200 Nonpathogen - hypothetical protein SACE_6771 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 134102306 Common ilvD5 dihydroxy-acid dehydratase SACE_5858 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 134098217 Nonpathogen - hypothetical protein SACE_1634 4 COG0640 ArsR, Predicted transcriptional regulators Transcription 134097982 Nonpathogen - hypothetical protein SACE_1396 1 None None None 134097099 Common ectC L-ectoine synthase SACE_0485 35 COG3257 GlxB, Uncharacterized protein, possibly involved in glyoxylate utilization General function prediction only 134098267 Common ctaE cytochrome c oxidase subunit III SACE_1684 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 134100234 Common - transporter, EamA family SACE_3696 56 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 134103594 Common - alcohol dehydrogenase, zinc-binding SACE_7172 127 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 134099240 Common dhbE 2,3-dihydroxybenzoate-AMP ligase SACE_2694 222 COG1021 EntE, Peptide arylation enzymes Secondary metabolites biosynthesis, transport, and catabolism 134098525 Nonpathogen - hypothetical protein SACE_1950 1 None None None 134099211 Common - hypothetical protein SACE_2664 18 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 134102001 Common poxB pyruvate decarboxylase SACE_5551 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 134102551 Nonpathogen - hypothetical protein SACE_6114 1 None None None 134098462 Common - phenylacetic acid degradation-related protein SACE_1886 24 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 134099863 Nonpathogen - hypothetical protein SACE_3324 1 None None None 134096794 Common - transcriptional regulator, XRE family SACE_0177 6 None None None 134097254 Common yihR predicted aldose-1-epimerase SACE_0644 51 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 134098545 Common - putative dihydrodipicolinate synthase SACE_1971 22 None None None 134100321 Common inhA enoyl-(acyl carrier protein) reductase SACE_3786 217 COG0623 FabI, Enoyl- acyl-carrier-protein 134101554 Common - NADH-dependent flavin oxidoreductase, Oye family SACE_5030 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 134099840 Common - poly-gamma-glutamate synthesis protein SACE_3301 54 COG2843 PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) Cell envelope biogenesis, outer membrane 134102678 Common - M protein SACE_6241 60 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 134100378 Common - transcriptional regulator, MerR family SACE_3843 21 COG0789 SoxR, Predicted transcriptional regulators Transcription 134103756 Common - DeoR-family transcriptional regulator SACE_7336 104 COG2378 COG2378, Predicted transcriptional regulator Transcription 134098264 Common trpD anthranilate phosphoribosyltransferase SACE_1681 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 134103505 Nonpathogen - hypothetical protein SACE_7080 1 None None None 134101538 Nonpathogen - hypothetical protein SACE_5010 4 None None None 134103415 Common tolA membrane spanning protein SACE_6989 3 None None None 134101046 Common - NAD/factor-dependent formaldehyde dehydrogenase SACE_4513 197 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 134098901 Common - sugar transporter, MFS superfamily SACE_2337 8 None None None 134097172 Common - hypothetical protein SACE_0561 16 COG2378 COG2378, Predicted transcriptional regulator Transcription 134103772 Nonpathogen - hypothetical protein SACE_7352 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 134097416 Common rplY 50S ribosomal protein L25 SACE_0811 155 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 134102637 Common - possible transferase SACE_6200 141 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 134103238 Common - ribosomal RNA adenine dimethylase domain protein SACE_6810 33 COG3963 COG3963, Phospholipid N-methyltransferase Lipid metabolism 134101228 Common - probable zinc-dependent alcohol dehydrogenase oxidoreductase protein SACE_4696 194 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 134098956 Common - short-chain dehydrogenase/reductase SDR SACE_2392 42 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134096899 Common - MarR-family transcriptional regulator SACE_0285 81 COG1846 MarR, Transcriptional regulators Transcription 134102040 Common - hypothetical protein SACE_5590 16 COG3361 COG3361, Uncharacterized conserved protein Function unknown 134103377 Common - putative RNA polymerase sigma factor SACE_6951 128 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 134100545 Common - metabolite transporter, MFS superfamily SACE_4010 129 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134099031 Common - iron sulphur binding protein SACE_2470 55 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 134099227 Common - transcriptional regulator, GntR family SACE_2681 152 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 134100745 Common - probable transcriptional regulator SACE_4212 73 COG1309 AcrR, Transcriptional regulator Transcription 134102804 Common - alpha-methylacyl-CoA racemase SACE_6370 108 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 134100917 Common - histidine kinase/response regulator hybrid protein SACE_4384 190 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 134098855 Common - hypothetical protein SACE_2287 7 COG4758 COG4758, Predicted membrane protein Function unknown 134102238 Common - putative substrate-binding transport protein SACE_5790 203 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 134103106 Common - O-methyltransferase-like protein SACE_6676 36 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 134102971 Common - probable multisubunit Na+:H+ antiporter MnhG subunit SACE_6539 33 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 134099165 Common - transposase SACE_2616 64 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134103541 Nonpathogen - hypothetical protein SACE_7118 5 None None None 134100733 Common prsR regulator of sigma factor SACE_4200 8 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 134099497 Common cydA cytochrome d ubiquinol oxidase, subunit I SACE_2955 167 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 134097825 Nonpathogen - hypothetical protein SACE_1236 3 COG0583 LysR, Transcriptional regulator Transcription 134097949 Common - protein of unknown function DUF1234 SACE_1363 50 COG3545 COG3545, Predicted esterase of the alpha/beta hydrolase fold General function prediction only 134100549 Common - alpha/beta hydrolase fold SACE_4014 130 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134096799 Common - hypothetical protein SACE_0182 55 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 134103207 Nonpathogen - hypothetical protein SACE_6778 1 None None None 134098133 Nonpathogen - hypothetical protein SACE_1547 1 None None None 134098349 Common - putative ECF-family RNA polymerase sigma factor SACE_1768 46 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 134099727 Common - terpene synthase, metal binding domain protein SACE_3187 12 None None None 134098677 Common - diaminopimelate decarboxylase SACE_2107 158 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 134099931 Nonpathogen - hypothetical protein SACE_3392 1 None None None 134096976 Common ybbC,yzbB hypothetical protein SACE_0362 51 COG3876 COG3876, Uncharacterized protein conserved in bacteria Function unknown 134103698 Common slpE peptidase SACE_7276 37 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134102191 Common gltB putative glutamate synthase(NADPH) large subunit SACE_5742 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 134100167 Common - TetR-family transcriptional regulator SACE_3629 16 COG1309 AcrR, Transcriptional regulator Transcription 134100435 Common metK putative S-adenosylmethionine synthetase SACE_3900 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 134102751 Common - sugar isomerase (SIS) SACE_6316 158 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 134100082 Common paaA1 phenylacetic acid degradation protein A SACE_3544 46 COG3396 COG3396, Uncharacterized conserved protein Function unknown 134102152 Common - amino acid permease-associated region SACE_5703 158 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 134102787 Nonpathogen - hypothetical protein SACE_6353 1 None None None 134101984 Common - hypothetical protein SACE_5533 2 None None None 134097504 Common - AsnC-family transcriptional regulator SACE_0906 74 COG1522 Lrp, Transcriptional regulators Transcription 134097489 Common - transcriptional regulator, TetR family SACE_0891 94 COG1309 AcrR, Transcriptional regulator Transcription 134101934 Common - ABC-2 type transporter SACE_5435 67 COG1511 COG1511, Predicted membrane protein Function unknown 134103734 Common - DGPFAETKE family protein SACE_7312 30 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 134099273 Nonpathogen - hypothetical protein SACE_2728 1 None None None 134099430 Common - aromatic-L-amino-acid decarboxylase SACE_2888 120 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 134102128 Common - alpha-ketoglutarate transporter, MFS superfamily SACE_5678 118 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134098154 Nonpathogen - hypothetical protein SACE_1568 1 None None None 134097579 Common - polyamine ABC transporter, ATP-binding protein SACE_0983 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 134102486 Common rplS 50S ribosomal protein L19 SACE_6049 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 134101096 Common - hypothetical protein SACE_4563 204 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 134098345 Common - vitamin B12-dependent ribonucleotide reductase SACE_1764 217 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 134102265 Common - hypothetical protein SACE_5817 5 None None None 134101736 Common engA GTP-binding protein EngA SACE_5232 218 COG1160 COG1160, Predicted GTPases General function prediction only 134101589 Common - protein kinase/transcriptional regulator, LuxR family SACE_5066 111 COG3903 COG3903, Predicted ATPase General function prediction only 134097806 Common bcp bacterioferritin comigratory protein SACE_1216 224 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 134102409 Common cobB cobyrinic acid a,c-diamide synthase SACE_5963 136 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 134100983 Common - hypothetical protein SACE_4450 2 COG3794 PetE, Plastocyanin Energy production and conversion 134099373 Common - probable Na(+)/glutamate:H(+) symporter SACE_2830 161 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 134103186 Common aceB,mas malate synthase SACE_6756 64 COG2225 AceB, Malate synthase Energy production and conversion 134098871 Common - recombinase SACE_2306 9 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 134100285 Nonpathogen - hypothetical protein SACE_3750 5 COG1309 AcrR, Transcriptional regulator Transcription 134101136 Common - transcriptional regulator, GntR family SACE_4603 133 COG1802 GntR, Transcriptional regulators Transcription 134098733 Nonpathogen - hypothetical protein SACE_2163 1 None None None 134097879 Common ornA oligoribonuclease SACE_1292 88 COG1949 Orn, Oligoribonuclease (3'->5' exoribonuclease) RNA processing and modification 134099268 Common - hypothetical protein SACE_2723 12 COG0439 AccC, Biotin carboxylase Lipid metabolism 134101003 Common - glycosyltransferase; possible macrolide glycosyltransferase SACE_4470 46 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 134103545 Common - protein of unknown function DUF305 SACE_7123 35 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 134102717 Common atpG ATP synthase gamma chain SACE_6281 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 134101450 Common - cytochrome P450 monooxygenase SACE_4920 69 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134098126 Common - twin-arginine translocation pathway signal SACE_1540 58 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 134098757 Common - ABC transporter, ATP-binding protein SACE_2187 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 134097939 Common - hypothetical protein SACE_1352 4 None None None 134103619 Common - TetR-family transcriptional regulator SACE_7197 21 COG1309 AcrR, Transcriptional regulator Transcription 134102400 Common - cobalamin biosynthesis protein CobG,precorrin-3B synthase SACE_5953 27 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 134103147 Nonpathogen - hypothetical protein SACE_6717 1 None None None 134100001 Common - amino acid transporter SACE_3463 16 None None None 134100582 Common - hypothetical protein SACE_4047 19 COG5552 COG5552, Uncharacterized conserved protein Function unknown 134097729 Nonpathogen - hypothetical protein SACE_1134 1 None None None 134099399 Common - possible secreted protein SACE_2856 7 None None None 134097636 Common - transcriptional regulator, MarR family SACE_1040 9 COG1846 MarR, Transcriptional regulators Transcription 134102887 Common - transposase SACE_6453 97 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 134103347 Nonpathogen - hypothetical protein SACE_6920 1 None None None 134098648 Common - putative transcriptional regulator (DNA-binding protein) SACE_2077 7 COG1395 COG1395, Predicted transcriptional regulator Transcription 134100845 Common - secreted trypsin-like serine protease SACE_4312 25 COG5640 COG5640, Secreted trypsin-like serine protease Posttranslational modification, protein turnover, chaperones 134098559 Nonpathogen - hypothetical protein SACE_1985 2 None None None 134101570 Common ydhC similar to transcriptional regulator (GntR family) SACE_5046 135 COG1802 GntR, Transcriptional regulators Transcription 134103497 Common - putative peptidyl-prolyl cis-trans isomerase SACE_7072 124 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 134098565 Common - FAD linked oxidase-like protein SACE_1991 11 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 134102381 Common - putative MFS transporter SACE_5934 126 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134102258 Common - hypothetical protein SACE_5810 5 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 134099614 Common hybG hydrogenase-2 operon protein SACE_3072 92 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 134100421 Common - oxidoreductase SACE_3886 62 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 134103501 Common - response regulator/thioredoxin-disulfide reductase SACE_7076 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 134096938 Common - NUDIX hydrolase SACE_0324 30 None None None 134098192 Common - hypothetical protein SACE_1608 40 COG4279 COG4279, Uncharacterized conserved protein Function unknown 134102668 Common - putative ABC transporter SACE_6231 42 COG3910 COG3910, Predicted ATPase General function prediction only 134098989 Common - hypothetical protein SACE_2427 25 COG0778 NfnB, Nitroreductase Energy production and conversion 134101396 Nonpathogen - hypothetical protein SACE_4866 1 None None None 134102099 Common - two component signal transduction response regulator SACE_5649 175 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 134097691 Nonpathogen - hypothetical protein SACE_1095 4 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134100492 Nonpathogen - hypothetical protein SACE_3957 1 None None None 134097614 Common dapE dipeptidase SACE_1018 186 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 134098482 Common - probable sugar efflux transporter, MFS superfamily SACE_1907 171 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134100210 Common - carboxylesterase, type B SACE_3672 62 COG2272 PnbA, Carboxylesterase type B Lipid metabolism 134100326 Common - glyoxalase/bleomycin resistance protein/dioxygenase SACE_3791 6 None None None 134097611 Common - hypothetical protein SACE_1015 3 None None None 134102661 Common cutA divalent cation tolerance protein SACE_6224 105 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 134097845 Nonpathogen - hypothetical protein SACE_1256 1 None None None 134096772 Common - putative secreted protein SACE_0155 6 None None None 134098452 Common - secreted protein SACE_1876 66 COG2706 COG2706, 3-carboxymuconate cyclase Carbohydrate transport and metabolism 134099530 Common - ABC transporter integral membrane protein SACE_2988 112 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 134097087 Nonpathogen - hypothetical protein SACE_0473 1 None None None 134103393 Common gpmA phosphoglycerate mutase SACE_6967 166 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 134103715 Nonpathogen - hypothetical protein SACE_7293 6 None None None 134102767 Common - secreted cellulose-binding protein SACE_6332 29 COG3397 COG3397, Uncharacterized protein conserved in bacteria Function unknown 134101257 Common - putative transmembrane transport protein SACE_4725 114 COG4147 DhlC, Predicted symporter General function prediction only 134097701 Common prfB putative peptide chain release factor 2 SACE_1105 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 134100961 Nonpathogen - hypothetical protein SACE_4428 4 None None None 134097659 Common - hypothetical protein SACE_1063 16 None None None 134097993 Common - hypothetical protein SACE_1407 9 None None None 134100315 Common - activator of HSP90 ATPase 1 family protein SACE_3780 17 COG3832 COG3832, Uncharacterized conserved protein Function unknown 134097940 Common - hypothetical protein SACE_1353 23 COG4552 Eis, Predicted acetyltransferase involved in intracellular survival and related acetyltransferases General function prediction only 134101932 Common - hypothetical protein SACE_5433 4 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 134102924 Common - response regulator, two-component system SACE_6491 218 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 134101585 Common - C4-dicarboxylate transport system (permease large protein) SACE_5061 121 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 134102617 Common - cell division FtsK/SpoIIIE SACE_6180 10 COG4249 COG4249, Uncharacterized protein containing caspase domain General function prediction only 134098687 Nonpathogen - hypothetical protein SACE_2117 1 None None None 134103471 Common - hypothetical protein SACE_7046 15 None None None 134096761 Common cydB cytochrome d ubiquinol oxidase subunit II SACE_0143 156 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 134101479 Common - short-chain dehydrogenase/reductase SDR SACE_4949 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 134102082 Common ilvB4 putative acetolactate synthase SACE_5632 215 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 134100559 Common - transcriptional regulator, GntR family SACE_4024 128 COG1802 GntR, Transcriptional regulators Transcription 134100466 Common - hypothetical protein SACE_3931 20 None None None 134098593 Common - methyltransferase type 11 SACE_2019 60 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 134101081 Common pdxA 4-hydroxythreonine-4-phosphate dehydrogenase SACE_4548 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 134102758 Common - ABC peptide transporter, membrane subunit SACE_6323 216 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 134096662 Common pknB serine/threonine protein kinase SACE_0044 158 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 134099348 Nonpathogen - hypothetical protein SACE_2803 1 None None None 134102737 Common - hypothetical protein SACE_6301 13 None None None 134101496 Common glpQ,ybeD glycerophosphoryl diester phosphodiesterase SACE_4968 169 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 134100906 Common - probable iron ABC transporter, ATP-binding protein SACE_4373 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 134097283 Common - lysozyme M1 precursor SACE_0675 49 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 134099767 Common - amidinotransferase SACE_3228 35 COG1834 COG1834, N-Dimethylarginine dimethylaminohydrolase Amino acid transport and metabolism 134102521 Nonpathogen - hypothetical protein SACE_6084 1 None None None 134096702 Common - drug resistance transporter, EmrB/QacA family SACE_0084 184 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134102047 Common - hypothetical protein SACE_5597 5 None None None 134101276 Common metE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase SACE_4744 141 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 134099961 Common - uncharacterized Fe-S protein SACE_3422 22 COG3217 COG3217, Uncharacterized Fe-S protein General function prediction only 134101098 Common ilvB1 acetolactate synthase SACE_4565 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 134101472 Common - IS1647-like transposase SACE_4942 37 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134101427 Nonpathogen - hypothetical protein SACE_4897 1 None None None 134100499 Common - hypothetical protein SACE_3964 19 COG4529 COG4529, Uncharacterized protein conserved in bacteria Function unknown 134101821 Nonpathogen - hypothetical protein SACE_5318 2 None None None 134103050 Common - 6-phosphogluconate dehydrogenase, NAD-binding SACE_6620 37 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 134097368 Common - putative two-component system sensor kinase SACE_0762 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 134102032 Nonpathogen - hypothetical protein SACE_5582 1 None None None 134100337 Common nirB nitrite reductase (NAD(P)H) large subunit SACE_3802 203 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 134101280 Common - protein kinase/transcriptional regulator, LuxR family SACE_4748 85 COG3903 COG3903, Predicted ATPase General function prediction only 134099349 Common - X-Pro dipeptidyl-peptidase-like protein SACE_2806 66 COG2936 COG2936, Predicted acyl esterases General function prediction only 134101760 Common argH argininosuccinate lyase SACE_5256 221 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 134101216 Common bioA adenosylmethionine-8-amino-7-oxononanoate aminotransferase SACE_4684 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 134102061 Common soxG sarcosine oxidase gamma subunit SACE_5611 30 COG4583 COG4583, Sarcosine oxidase gamma subunit Amino acid transport and metabolism 134102512 Nonpathogen - hypothetical protein SACE_6075 2 None None None 134097591 Common - putative ABC transporter ATP-binding protein SACE_0995 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 134099406 Common - alpha-ketoglutarate transporter, MFS superfamily SACE_2864 124 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134102671 Common dinX DNA polymerase IV SACE_6234 183 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 134103098 Common - succinyl-CoA synthetase subunit alpha SACE_6668 214 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 134098580 Common - hypothetical protein SACE_2006 24 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 134097799 Common murI glutamate racemase SACE_1209 187 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 134097624 Common echA11 putative enoyl-CoA hydratase/isomerase family protein SACE_1028 150 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 134100016 Common - putative fatty-acid--CoA ligase SACE_3478 213 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 134100398 Common - transmembrane efflux protein SACE_3863 189 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134098167 Common cobC hypothetical protein SACE_1581 210 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 134099335 Common - secreted hydrolase SACE_2790 37 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134102029 Nonpathogen - hypothetical protein SACE_5579 1 None None None 134103600 Nonpathogen - hypothetical protein SACE_7178 1 None None None 134103490 Common agaB2 putative alpha-galactosidase SACE_7065 14 COG3345 GalA, Alpha-galactosidase Carbohydrate transport and metabolism 134097054 Nonpathogen - hypothetical protein SACE_0441 1 None None None 134099456 Common - hypothetical protein SACE_2914 41 COG3564 COG3564, Uncharacterized protein conserved in bacteria Function unknown 134100162 Nonpathogen - hypothetical protein SACE_3624 4 None None None 134103707 Common - putative ABC transporter permease protein SACE_7285 176 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 134098115 Common - hypothetical protein SACE_1529 16 None None None 134102574 Common gpdA2 glycerol-3-phosphate dehydrogenase (NAD(P)+) SACE_6137 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 134100966 Common - ABC transporter, ATP-binding component SACE_4433 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 134102231 Common - permeases of drug/metabolite transporter superfamily SACE_5783 124 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 134103779 Common ino1 putative myo-inositol-1-phosphate synthase SACE_7359 51 COG1260 INO1, Myo-inositol-1-phosphate synthase Lipid metabolism 134096739 Common - SSS sodium solute transporter superfamily SACE_0121 128 COG4147 DhlC, Predicted symporter General function prediction only 134097464 Nonpathogen - hypothetical protein SACE_0861 1 None None None 134098500 Common - putative transposase SACE_1925 72 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 134099815 Common idhA2 myo-inositol 2-dehydrogenase SACE_3276 181 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 134097430 Common - glucose dehydrogenase (pyrroloquinoline-quinone) SACE_0825 115 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 134102892 Common - hypothetical protein SACE_6459 10 COG2835 COG2835, Uncharacterized conserved protein Function unknown 134103518 Common - isomerase SACE_7095 19 None None None 134097364 Common - carboxyvinyl-carboxyphosphonate phosphorylmutase SACE_0758 94 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 134103583 Common - RNA polymerase ECF sigma factor SACE_7161 96 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 134098070 Common - hypothetical protein SACE_1484 48 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 134102257 Nonpathogen - hypothetical protein SACE_5809 1 None None None 134101869 Common - secreted tripeptidyl aminopeptidase SACE_5367 7 None None None 134103441 Nonpathogen - hypothetical protein SACE_7016 1 None None None 134098762 Nonpathogen - hypothetical protein SACE_2192 1 None None None 134100891 Common - gluconate permease SACE_4358 78 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 134101862 Common - putative tricarboxylic transport membrane protein SACE_5360 75 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 134099978 Common - hypothetical protein SACE_3440 16 None None None 134097420 Common - hypothetical protein SACE_0815 52 COG0778 NfnB, Nitroreductase Energy production and conversion 134098596 Common ruvA Holliday junction DNA helicase motor protein SACE_2022 210 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 134100309 Common - hypothetical protein SACE_3774 18 COG2855 COG2855, Predicted membrane protein Function unknown 134100107 Nonpathogen - integral membrane protein SACE_3569 3 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 134099218 Common - putative oligopeptide ABC transporter ATP-binding protein SACE_2671 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 134099418 Common gdmF 3-amino-5-hydroxybenzoic acid synthase (AHBA synthase) SACE_2876 39 COG2162 NhoA, Arylamine N-acetyltransferase Secondary metabolites biosynthesis, transport, and catabolism 134097167 Common - ABC-type nitrate/sulfonate/bicarbonate transport systems-like protein SACE_0556 95 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 134097208 Common - hypothetical protein SACE_0598 18 None None None 134096924 Common - methyltransferase SACE_0310 31 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134103421 Common - N-succinyldiaminopimelate aminotransferase SACE_6995 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 134097405 Common metS methionyl-tRNA synthetase SACE_0799 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 134098107 Common - hypothetical protein SACE_1521 17 None None None 134098087 Common - hypothetical protein SACE_1501 43 COG1434 COG1434, Uncharacterized conserved protein Function unknown 134100827 Common bam amidase SACE_4294 214 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 134096925 Common - metallophosphoesterase SACE_0311 78 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 134101266 Common hadL haloalkanoic acid dehalogenase SACE_4734 45 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 134102050 Common - hydrolase SACE_5600 22 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 134099680 Nonpathogen - hypothetical protein SACE_3138 1 None None None 134101457 Common - halogenase B SACE_4927 40 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 134101814 Common - hypothetical protein SACE_5311 3 None None None 134103401 Common - ErfK/YbiS/YcfS/YnhG SACE_6975 17 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 134102090 Common - arginine/ornithine transport system ATPase SACE_5640 99 COG1703 ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family Amino acid transport and metabolism 134099124 Common - toprim domain protein SACE_2569 7 None None None 134101088 Common - aldo/keto reductase SACE_4555 184 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 134098385 Common - hypothetical protein SACE_1806 16 None None None 134099090 Nonpathogen - surface protein, pentapeptide repeat domain SACE_2534 1 None None None 134100907 Common - iron compound ABC transporter, permease protein SACE_4374 184 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 134103164 Common - putative allantoicase (allantoate amidinohydrolase) (partial match) SACE_6734 50 COG3195 COG3195, Uncharacterized protein conserved in bacteria Function unknown 134100209 Common - beta-lactamase-like protein SACE_3671 82 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 134100701 Common - integral membrane protein SACE_4168 9 COG4129 COG4129, Predicted membrane protein Function unknown 134099084 Nonpathogen - hypothetical protein SACE_2528 1 None None None 134099469 Common - transcriptional regulator, SARP family SACE_2927 25 COG3629 DnrI, DNA-binding transcriptional activator of the SARP family Signal transduction mechanisms 134096848 Common tyrA prephenate dehydrogenase SACE_0231 140 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 134097445 Common - protein of unknown function DUF501 SACE_0840 27 COG1507 COG1507, Uncharacterized conserved protein Function unknown 134098315 Nonpathogen - hypothetical protein SACE_1733 1 None None None 134099836 Common cobW cobalamin synthesis protein SACE_3297 119 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 134102623 Common - monooxygenase, FAD-binding SACE_6186 68 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 134101413 Common - ABC transporter permease protein SACE_4883 149 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 134101889 Common - predicted branched-chain amino acid permease SACE_5387 7 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 134099646 Nonpathogen - hypothetical protein SACE_3104 4 None None None 134098668 Nonpathogen - hypothetical protein SACE_2097 1 None None None 134100387 Common dhbB isochorismatase (2,3 dihydro-2,3 dihydroxybenzoate synthase) SACE_3852 31 COG1535 EntB, Isochorismate hydrolase Secondary metabolites biosynthesis, transport, and catabolism 134103666 Common - DeoR-family transcriptional regulator SACE_7244 29 COG2378 COG2378, Predicted transcriptional regulator Transcription 134102475 Common tsf elongation factor Ts SACE_6037 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 134100233 Common - transcriptional regulator, LysR family SACE_3695 177 COG0583 LysR, Transcriptional regulator Transcription 134098163 Common - hypothetical protein SACE_1577 41 COG3346 COG3346, Uncharacterized conserved protein Function unknown 134101753 Common - putative inorganic polyphosphate/ATP-NAD kinase SACE_5249 229 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 134100914 Common - mandelate racemase/muconate lactonizing enzyme-like protein SACE_4381 133 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 134103761 Nonpathogen - hypothetical protein SACE_7341 1 None None None 134096709 Nonpathogen - hypothetical protein SACE_0091 1 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 134099661 Common hisD2 histidinol dehydrogenase SACE_3119 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 134099987 Common - gluconolactonase precursor SACE_3449 61 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 134101697 Common iolC sugar kinase, ribokinase family SACE_5189 73 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 134099442 Common - probable glyoxalase/bleomycin resistance protein, dioxygenase superfamily SACE_2900 34 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 134102372 Common - protein of unknown function DUF503 SACE_5925 37 COG1550 COG1550, Uncharacterized protein conserved in bacteria Function unknown 134097423 Common - hypothetical protein SACE_0818 179 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 134099892 Common - helicase RecD/TraA SACE_3353 130 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 134101925 Common - polysaccharide deacetylase SACE_5426 62 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 134098302 Common - protein of unknown function DUF885 SACE_1720 38 COG4805 COG4805, Uncharacterized protein conserved in bacteria Function unknown 134099751 Common - DegT/DnrJ/EryC1/StrS aminotransferase family protein SACE_3212 193 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 134097316 Common - putative peptidyl-prolyl cis-trans isomerase SACE_0709 165 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 134099777 Common - FHA domain containing protein SACE_3238 60 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 134098928 Common - secreted protein SACE_2364 3 None None None 134098185 Common - NADPH-dependent F420 reductase SACE_1601 46 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 134097964 Common - transcriptional regulator, XRE family SACE_1378 6 COG1396 HipB, Predicted transcriptional regulators Transcription 134098076 Common - hypothetical protein SACE_1490 14 None None None 134101662 Common bga2 putative beta-galactosidase SACE_5154 39 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 134102436 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase SACE_5992 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 134098180 Nonpathogen - hypothetical protein SACE_1596 3 None None None 134099870 Common recQ ATP-dependent DNA helicase SACE_3331 212 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 134099770 Common yqiA multidrug transporter SACE_3231 165 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134102728 Common prfA putative peptide chain release factor 1 SACE_6292 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 134097114 Common tnp transposase, ISlxx5 SACE_0502 63 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 134101635 Common - integrase SACE_5125 8 None None None 134098321 Common kdgA KHG/KDPG aldolase SACE_1739 125 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 134101268 Common - oxidoreductase SACE_4736 144 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134098938 Common - alcohol dehydrogenase, zinc-binding SACE_2374 212 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 134102582 Common - transcriptional regulator, IclR family SACE_6145 88 COG1414 IclR, Transcriptional regulator Transcription 134101164 Common - putative branched-chain amino acid binding protein SACE_4631 141 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 134097760 Common - hypothetical protein SACE_1168 5 None None None 134098144 Common - DNA-cytosine methyltransferase SACE_1558 52 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 134103105 Common - UDP-glucose:sterol glucosyltransferase SACE_6675 34 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 134102039 Common - hypothetical protein SACE_5589 7 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 134102350 Common - hypothetical protein SACE_5903 7 COG4226 HicB, Uncharacterized protein encoded in hypervariable junctions of pilus gene clusters Function unknown 134096865 Common - aminoglycoside phosphotransferase SACE_0250 5 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 134099191 Common - transcriptional regulator, LysR family SACE_2644 179 COG0583 LysR, Transcriptional regulator Transcription 134099076 Common - hypothetical protein SACE_2519 6 None None None 134103644 Common - SWIM zinc finger domain protein SACE_7222 29 COG4279 COG4279, Uncharacterized conserved protein Function unknown 134098420 Common - transcriptional regulator, XRE family SACE_1844 41 COG1396 HipB, Predicted transcriptional regulators Transcription 134099230 Common - general substrate transporter SACE_2684 168 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134100220 Common - hydrolase, alpha/beta fold family SACE_3682 99 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134097884 Common thiD phosphomethylpyrimidine kinase SACE_1297 220 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 134100780 Common - cyanate MFS transporter SACE_4247 11 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 134098276 Common - putative long-chain fatty acid ligase SACE_1694 213 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 134100056 Common - xylose isomerase-like TIM barrel SACE_3518 22 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 134101747 Common nudF ADP-ribose pyrophosphatase SACE_5243 144 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 134098993 Common - conserved hypothetical membrane permease protein SACE_2431 18 COG0730 COG0730, Predicted permeases General function prediction only 134102477 Common - putative peptidase SACE_6039 20 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 134097708 Common - putative amidohydrolase (isochorismatase) SACE_1113 131 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 134097375 Common mscL large-conductance mechanosensitive channel SACE_0769 59 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 134099204 Nonpathogen - hypothetical protein SACE_2657 1 None None None 134103710 Common - hypothetical protein SACE_7288 28 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 134098634 Nonpathogen - hypothetical protein SACE_2064 1 None None None 134100647 Common ehpF putative phenazine antibiotic biosynthesis protein SACE_4113 8 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 134100705 Common - hypothetical protein SACE_4172 10 None None None 134099491 Common - hypothetical protein SACE_2949 60 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 134102368 Common dinF DNA-damage-inducible protein F SACE_5921 121 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 134097243 Common citA citrate synthase SACE_0633 181 COG0372 GltA, Citrate synthase Energy production and conversion 134096648 Common - probable ATP-dependent Clp protease ATP-binding subunit SACE_0030 4 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 134098093 Common - hypothetical protein SACE_1507 3 None None None 134099838 Common - probable transcriptional regulator, MarR family SACE_3299 108 COG1846 MarR, Transcriptional regulators Transcription 134100115 Nonpathogen - hypothetical protein SACE_3577 1 COG3339 COG3339, Uncharacterized conserved protein Function unknown 134097149 Common - carbon monoxide dehydrogenase medium subunit SACE_0538 97 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 134101513 Nonpathogen - hypothetical protein SACE_4985 1 None None None 134102815 Nonpathogen - hypothetical protein SACE_6381 1 None None None 134097739 Common - AraC-family transcriptional regulator SACE_1147 133 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 134103262 Common rplW 50S ribosomal protein L23 SACE_6834 127 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 134096870 Common recR recombination protein RecR SACE_0255 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 134097731 Common - hypothetical protein SACE_1136 4 None None None 134098172 Common - putative secreted sugar-binding protein SACE_1586 75 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 134097817 Common - hypothetical protein SACE_1228 21 COG3714 COG3714, Predicted membrane protein Function unknown 134097042 Common - ABC-2 type transporter SACE_0429 30 COG1511 COG1511, Predicted membrane protein Function unknown 134101236 Common - AsnC-family transcriptional regulator SACE_4704 155 COG1522 Lrp, Transcriptional regulators Transcription 134097094 Nonpathogen - hypothetical protein SACE_0480 1 None None None 134102875 Nonpathogen - hypothetical protein SACE_6441 1 None None None 134096888 Common leuA 2-isopropylmalate synthase SACE_0274 211 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 134096900 Common - protein of unknown function DUF820 SACE_0286 18 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 134100313 Common - GntR-family transcriptional regulator SACE_3778 91 COG1802 GntR, Transcriptional regulators Transcription 134096968 Nonpathogen - hypothetical protein SACE_0354 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 134103574 Nonpathogen - hypothetical protein SACE_7152 1 None None None 134100136 Common map2 methionine aminopeptidase SACE_3598 216 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 134096787 Common - transcriptional regulator, XRE family SACE_0170 6 None None None 134102707 Common - putative adenosylcobalamin-dependent diol dehydratase gamma subunit SACE_6271 131 COG2096 COG2096, Uncharacterized conserved protein Function unknown 134102914 Common - possible transcriptional regulator, LytR family SACE_6481 55 COG1316 LytR, Transcriptional regulator Transcription 134102846 Common - putative ABC transporter ATP-binding subunit SACE_6412 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 134099484 Common - hypothetical protein SACE_2942 8 COG3393 COG3393, Predicted acetyltransferase General function prediction only 134099877 Common - glyoxalase/bleomycin resistance protein/dioxygenase SACE_3338 19 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 134102024 Common - HAD-superfamily hydrolase subfamily IIIA SACE_5574 102 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 134100877 Common - mandelate racemase/muconate lactonizing enzyme-like protein SACE_4344 125 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 134100242 Common - pyridoxamine 5'-phosphate oxidase-related,FMN-binding protein SACE_3706 11 None None None 134100395 Common - hypothetical protein SACE_3860 2 None None None 134103135 Common choD cholesterol oxidase SACE_6705 38 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 134101819 Common - metallo-beta-lactamase superfamily protein SACE_5316 203 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 134099742 Common - putative UDP-glucose/GDP-mannose dehydrogenase SACE_3203 200 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 134098781 Common draG1 ADP-ribosylglycohydrolase SACE_2211 9 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 134102209 Nonpathogen - hypothetical protein SACE_5760 1 None None None 134101339 Nonpathogen - hypothetical protein SACE_4810 2 None None None 134103364 Common - protein of unknown function DUF1526 SACE_6937 20 None None None 134101656 Common embC arabinosyl transferase SACE_5147 5 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 134103468 Common - putative ABC transporter, integral membrane subunit SACE_7043 8 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 134099769 Common add adenosine deaminase SACE_3230 103 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 134097265 Common tnp9B transposase, IS4 family SACE_0656 23 None None None 134099435 Common cysK cysteine synthase A SACE_2893 208 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 134102693 Common - amino acid permease-associated region SACE_6257 83 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 134102798 Common glcF glycolate oxidase iron-sulfur subunit SACE_6364 182 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 134098205 Common - transcriptional regulator, IclR family/regucalcin SACE_1622 84 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 134101189 Common iolH myo-inositol catabolism SACE_4656 28 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 134100554 Common - carbon-monoxide dehydrogenase SACE_4019 115 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 134101847 Common - glycoside hydrolase, family 25 SACE_5345 44 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 134097967 Common - dehydrogenase (secreted protein) SACE_1381 10 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 134098991 Common - beta-lactamase-like protein SACE_2429 90 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 134097525 Common adh10 zinc-binding dehydrogenase SACE_0927 207 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 134103021 Nonpathogen - hypothetical protein SACE_6590 1 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 134099949 Common - fumarylacetoacetate hydrolase SACE_3410 35 COG3970 COG3970, Fumarylacetoacetate (FAA) hydrolase family protein General function prediction only 134099532 Common - secreted glycosyl hydrolase SACE_2990 12 COG3828 COG3828, Uncharacterized protein conserved in bacteria Function unknown 134100090 Common - selenocysteine synthase SACE_3552 64 COG1921 SelA, Selenocysteine synthase [seryl-tRNASer selenium transferase] Amino acid transport and metabolism 134098308 Common - putative pyridoxal-phosphate dependent enzyme SACE_1726 210 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 134097480 Common - hypothetical protein SACE_0882 12 None None None 134098404 Common tpase1 transposase SACE_1826 97 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 134101494 Nonpathogen - hypothetical protein SACE_4965 1 None None None 134102158 Common - integral membrane transport protein SACE_5709 95 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134097881 Nonpathogen - hypothetical protein SACE_1294 1 None None None 134097297 Common - putative signal transduction histidine kinase membrane protein SACE_0690 25 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 134100516 Common - transport integral membrane protein SACE_3981 159 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134101745 Common - chromosome partitioning protein (partial match) SACE_5241 229 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 134099620 Nonpathogen - hypothetical protein SACE_3078 3 None None None 134103381 Common - phospholipid/glycerol acyltransferase SACE_6955 42 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 134098628 Common ptsH phosphocarrier protein hpr SACE_2058 12 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 134102336 Common - cell division FtsK/SpoIIIE SACE_5889 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 134097841 Common - transcriptional regulator, TetR family SACE_1252 15 COG1309 AcrR, Transcriptional regulator Transcription 134100042 Common - acyl-CoA dehydrogenase-like SACE_3504 38 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134099074 Common - insertion element transposase SACE_2517 21 None None None 134101995 Common aroH phospho-2-dehydro-3-deoxyheptonate aldolase SACE_5545 73 COG3200 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 134100156 Nonpathogen - hypothetical protein SACE_3618 1 None None None 134101341 Common rhsA rhs protein SACE_4812 73 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 134101068 Common - hypothetical protein SACE_4535 8 None None None 134103074 Common - phosphonate ABC transporter, ATP-binding protein SACE_6644 249 COG3638 COG3638, ABC-type phosphate/phosphonate transport system, ATPase component Inorganic ion transport and metabolism 134103654 Common - AraC-family transcriptional regulator SACE_7232 119 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 134101685 Common - hypothetical protein SACE_5177 12 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 134099258 Common - hypothetical protein SACE_2713 4 None None None 134103123 Common - hypothetical protein SACE_6693 52 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 134103436 Nonpathogen - hypothetical protein SACE_7011 1 None None None 134099355 Common - hypothetical protein SACE_2812 4 COG2246 COG2246, Predicted membrane protein Function unknown 134099147 Common - glucose-methanol-choline oxidoreductase SACE_2592 92 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 134099629 Nonpathogen - hypothetical protein SACE_3087 1 None None None 134100678 Common - HTH transcriptional regulator, XRE family, cupin domain SACE_4145 48 COG1396 HipB, Predicted transcriptional regulators Transcription 134096901 Common - starvation-response DNA binding protein SACE_0287 122 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 134101644 Common - hypothetical protein SACE_5134 23 None None None 134102602 Common - possible glucose dehydrogenase SACE_6165 24 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 134098389 Common - probable conserved integral membrane alanine and leucine rich protein SACE_1810 17 None None None 134098703 Nonpathogen - hypothetical protein SACE_2133 2 None None None 134101959 Common cyp2 cytochrome P450 SACE_5461 62 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134099607 Nonpathogen - hypothetical protein SACE_3065 2 None None None 134103562 Nonpathogen - hypothetical protein SACE_7140 4 None None None 134100299 Common - lysozyme M1 precursor SACE_3764 40 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 134102942 Common - acetyl/propionyl-CoA carboxylase alpha subunit SACE_6509 238 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 134101839 Nonpathogen - hypothetical protein SACE_5337 1 None None None 134102851 Common pteG cholesterol oxidase SACE_6417 32 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 134102686 Common - aldehyde dehydrogenase (NAD+) SACE_6249 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 134097068 Common - transcriptional regulatory protein (probably LacI-family) SACE_0455 127 COG1609 PurR, Transcriptional regulators Transcription 134102079 Nonpathogen - hypothetical protein SACE_5629 1 None None None 134102978 Common - hypothetical protein SACE_6546 148 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 134102648 Common - transcriptional regulator, XRE family SACE_6211 6 None None None 134103076 Common - haloacid dehalogenase domain protein hydrolase SACE_6646 102 COG0546 Gph, Predicted phosphatases General function prediction only 134099177 Common - modular ype I polyketide synthase SACE_2629 215 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134100164 Common - alpha/beta hydrolase fold SACE_3626 78 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134099550 Common - hypothetical protein SACE_3008 5 COG4319 COG4319, Ketosteroid isomerase homolog Function unknown 134099686 Common mdlD benzaldehyde dehydrogenase (NAD+) SACE_3144 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 134100448 Common - similar to glycosyltransferase probably involved in cell wall biogenesis SACE_3913 79 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 134101544 Common acdA acyl-CoA dehydrogenase SACE_5017 134 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134098135 Common - hypothetical protein SACE_1549 23 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 134101952 Common - multiple sugar transport system permease protein SACE_5454 145 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 134103310 Common - nucleotide-binding protein SACE_6882 107 COG1666 COG1666, Uncharacterized protein conserved in bacteria Function unknown 134100596 Common - FMNH2-dependent monooxygenase SACE_4061 85 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134098054 Common draG3 ADP-ribosylglycohydrolase SACE_1468 70 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 134102415 Common - probable multidrug resistance transporter, MFS superfamily SACE_5969 7 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 134098310 Common - monooxygenase, FAD-binding SACE_1728 66 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 134099697 Common - large transcriptional regulator SACE_3156 91 COG3899 COG3899, Predicted ATPase General function prediction only 134098142 Common vsr very short patch repair protein SACE_1556 70 COG3727 Vsr, DNA G:T-mismatch repair endonuclease DNA replication, recombination, and repair 134097970 Common valS valyl-tRNA synthetase SACE_1384 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 134098898 Common - transposase for IS3508i SACE_2334 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 134101303 Nonpathogen - hypothetical protein SACE_4771 1 None None None 134099823 Nonpathogen - hypothetical protein SACE_3284 2 None None None 134099576 Common - possible ABC Fe(3+) transporter binding protein SACE_3034 72 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 134098720 Common - cation transporter SACE_2150 92 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 134102274 Common - hypothetical protein SACE_5826 6 COG4113 COG4113, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 134102583 Nonpathogen - hypothetical protein SACE_6146 1 None None None 134100817 Common - MbtH-like protein SACE_4284 37 COG3251 COG3251, Uncharacterized protein conserved in bacteria Function unknown 134100795 Common - putative IS200-like transposase SACE_4262 64 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 134100952 Common - integral membrane protein SACE_4419 30 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 134101727 Common csbX alpha-ketoglutarate permease SACE_5222 47 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134102361 Common - polynucleotide phosphorylase/polyadenylase SACE_5914 236 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 134100349 Common dinP DNA polymerase IV SACE_3814 181 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 134101930 Common rpsA 30S ribosomal protein S1 SACE_5431 227 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 134096879 Common - probable transcriptional regulator, LysR family SACE_0264 166 COG0583 LysR, Transcriptional regulator Transcription 134101001 Common - aldehyde oxidase and xanthine dehydrogenase family protein SACE_4468 117 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 134100281 Common - putative transporter SACE_3746 60 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134100139 Nonpathogen - hypothetical protein SACE_3601 1 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 134096980 Common - type II secretion system protein E SACE_0367 149 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 134097222 Common - probable multidrug efflux transport protein SACE_0612 132 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134102595 Common ilvH acetolactate synthase 3 regulatory subunit SACE_6158 193 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 134097280 Common - conserved protein (PRC-barrel domain) SACE_0672 8 None None None 134101790 Common chiC glycosyl hydrolase, family 18 SACE_5287 18 None None None 134100633 Common - methylated-DNA--protein-cysteine methyltransferase SACE_4099 216 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 134097834 Common - possible cell wall protein SACE_1245 17 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 134102452 Common - aldehyde dehydrogenase (NAD+) SACE_6014 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 134101128 Common - ErfK/YbiS/YcfS/YnhG SACE_4595 19 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 134098006 Common kgtP putative MFS dicarboxylate transporter SACE_1420 123 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134098947 Nonpathogen - hypothetical protein SACE_2383 1 None None None 134099126 Common - oxidoreductase SACE_2571 13 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 134099289 Common - phosphotransferase SACE_2744 58 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 134097926 Common - membrane alanyl aminopeptidase SACE_1339 164 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 134102954 Nonpathogen - hypothetical protein SACE_6521 1 None None None 134102386 Common bioI cytochrome p450-like enzyme SACE_5939 87 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 134097072 Common - hypothetical protein SACE_0459 6 None None None 134100102 Common - polysulphide reductase, NrfD SACE_3564 7 COG3301 NrfD, Formate-dependent nitrite reductase, membrane component Inorganic ion transport and metabolism 134096912 Common - hypothetical protein SACE_0298 14 COG1309 AcrR, Transcriptional regulator Transcription 134097344 Nonpathogen - hypothetical protein SACE_0738 1 None None None 134102837 Common hutI putative imidazolonepropionase (imidazolone-5-propionate hydrolase) SACE_6403 101 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 134100778 Nonpathogen - hypothetical protein SACE_4245 1 None None None 134103065 Nonpathogen - hypothetical protein SACE_6635 3 None None None 134100486 Common - transcriptional regulator, AsnC family SACE_3951 162 COG1522 Lrp, Transcriptional regulators Transcription 134099317 Common - hypothetical protein SACE_2772 8 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134097415 Common pth peptidyl-tRNA hydrolase SACE_0810 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 134099806 Common - Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase SACE_3267 48 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 134103214 Nonpathogen - hypothetical protein SACE_6785 1 None None None 134102070 Common - hypothetical protein SACE_5620 80 COG1742 COG1742, Uncharacterized conserved protein Function unknown 134099115 Nonpathogen - hypothetical protein SACE_2560 1 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 134099886 Common - hypothetical protein SACE_3347 5 None None None 134101858 Common - ethanolamine permease SACE_5356 163 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 134102981 Common - protein of unknown function DUF574 SACE_6549 12 None None None 134097355 Common - putative responce regulator with diguanylate cyclase SACE_0749 168 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 134103739 Common - probable histidine triad (HIT) protein SACE_7317 219 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 134099131 Common tnp9B transposase, IS4 family SACE_2576 19 None None None 134101853 Common - GntR-family transcriptional regulator SACE_5351 132 COG2186 FadR, Transcriptional regulators Transcription 134097238 Nonpathogen - hypothetical protein SACE_0628 1 None None None 134097567 Nonpathogen - hypothetical protein SACE_0971 4 COG5373 COG5373, Predicted membrane protein Function unknown 134099282 Common - hypothetical protein SACE_2737 4 None None None 134099350 Nonpathogen - transcriptional regulator, TetR family SACE_2807 4 COG1309 AcrR, Transcriptional regulator Transcription 134101387 Common ydeG similar to metabolite transport protein SACE_4857 17 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 134102607 Common - hypothetical protein SACE_6170 13 COG5502 COG5502, Uncharacterized conserved protein Function unknown 134100077 Common crtB phytoene synthase SACE_3539 110 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 134097142 Nonpathogen - hypothetical protein SACE_0531 1 None None None 134103206 Nonpathogen - hypothetical protein SACE_6777 1 None None None 134100110 Common - secreted protein SACE_3572 13 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 134102144 Common - hypothetical protein SACE_5695 19 COG5564 COG5564, Predicted TIM-barrel enzyme, possibly a dioxygenase General function prediction only 134096621 Common dnaA chromosomal replication initiation protein SACE_0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 134100340 Common - chalcone/stilbene synthase family protein SACE_3805 15 COG2138 COG2138, Uncharacterized conserved protein Function unknown 134096959 Common - anion/cation symporter, MFS superfamily SACE_0345 90 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 134097565 Common gvpL2 gas vesicle synthesis protein SACE_0969 11 None None None 134103194 Common alr alanine racemase SACE_6764 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 134101615 Common - site-specific recombinase, phage integrase family SACE_5095 69 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 134100449 Common ydhD peptidoglycan hydrolase SACE_3914 40 COG3858 COG3858, Predicted glycosyl hydrolase General function prediction only 134102007 Common - CsbD-like protein SACE_5557 20 None None None 134097011 Common folP 7,8-dihydropteroate synthase (partial match) SACE_0398 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 134099028 Common - possible universal stress protein SACE_2466 17 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 134097912 Common gudB NAD-specific glutamate dehydrogenase SACE_1325 77 COG2902 COG2902, NAD-specific glutamate dehydrogenase Amino acid transport and metabolism 134100804 Nonpathogen - hypothetical protein SACE_4271 2 None None None 134099506 Common - transcriptional regulator, GntR family SACE_2964 127 COG2188 PhnF, Transcriptional regulators Transcription 134100038 Common - amino acid permease-associated region SACE_3500 39 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 134102030 Common - glycosyl transferase, family 2 SACE_5580 47 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 134103705 Common - membrane-associated oxidoreductase SACE_7283 7 None None None 134099047 Common - choline/carnitine/betaine transporter SACE_2490 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 134101709 Common iolF,yxdF inositol transport protein SACE_5203 99 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134102890 Common manA mannose-6-phosphate isomerase SACE_6457 41 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 134099016 Common - putative transmembrane protein SACE_2454 17 COG3174 COG3174, Predicted membrane protein Function unknown 134099775 Common - integral membrane protein SACE_3236 7 None None None 134098289 Common - integral membrane protein SACE_1707 8 None None None 134101500 Common - cation-binding protein, hemerythrin HHE family SACE_4972 38 None None None 134103691 Common - secreted trypsin-like serine protease SACE_7269 22 COG5640 COG5640, Secreted trypsin-like serine protease Posttranslational modification, protein turnover, chaperones 134097828 Common - hypothetical protein SACE_1239 40 COG1309 AcrR, Transcriptional regulator Transcription 134098696 Common - hypothetical protein SACE_2126 9 None None None 134098706 Common pyrD dihydroorotate dehydrogenase SACE_2136 135 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 134097773 Nonpathogen - hypothetical protein SACE_1183 1 None None None 134100469 Common - oxidoreductase SACE_3934 46 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 134097351 Common - transposase, ISlxx1-degenerated SACE_0745 54 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 134097500 Common metB cystathionine gamma-synthase SACE_0902 207 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 134102367 Common def polypeptide deformylase SACE_5920 211 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 134096783 Common - galactofuranosyl transferase SACE_0166 18 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 134097715 Common - phenylacetate-coenzyme A ligase SACE_1120 109 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 134100590 Common - tryptophan 2,3-dioxygenase SACE_4055 42 COG3483 TDO2, Tryptophan 2,3-dioxygenase (vermilion) Amino acid transport and metabolism 134101057 Common - hypothetical protein SACE_4524 12 None None None 134097677 Common - possible transmembrane cation transporter SACE_1081 84 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 134100722 Common - putative DNA polymerase related protein SACE_4189 29 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 134100754 Common - hypothetical protein SACE_4221 38 COG0628 PerM, Predicted permease General function prediction only 134101575 Common dctA C4-dicarboxylate transport protein SACE_5051 158 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 134097758 Common - hypothetical protein SACE_1166 4 None None None 134099475 Common pnbA putative para-nitrobenzyl esterase SACE_2933 57 COG2272 PnbA, Carboxylesterase type B Lipid metabolism 134098434 Common - protein of unknown function DUF6, transmembrane SACE_1858 52 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 134099566 Common - transposase SACE_3024 64 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134100568 Common - hypothetical protein SACE_4033 94 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 134098906 Common - modular polyketide synthase SACE_2342 211 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134100528 Common - long-chain-acyl-CoA dehydrogenase SACE_3993 161 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 134100271 Nonpathogen - hypothetical protein SACE_3736 1 None None None 134100854 Common - glycosyl transferase, family 39 SACE_4321 6 COG5305 COG5305, Predicted membrane protein Function unknown 134103332 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase SACE_6904 221 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134100669 Common - oxidoreductase SACE_4136 170 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 134103476 Common - putative salicylate monooxygenase SACE_7051 85 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 134100843 Nonpathogen - hypothetical protein SACE_4310 5 None None None 134098910 Common - UDP-glucuronosyltransferase SACE_2346 48 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 134101039 Common - putative transposase SACE_4506 69 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 134102961 Common - transcriptional regulator, DeoR family SACE_6528 115 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 134098967 Common - probable pyruvate dehydrogenase, E2 component,dihydrolipoamide acetyltransferase SACE_2405 180 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 134100300 Common - probable transcriptional regulator, LytR family SACE_3765 60 COG1316 LytR, Transcriptional regulator Transcription 134102166 Common - transcriptional regulator, AsnC family SACE_5717 140 COG1522 Lrp, Transcriptional regulators Transcription 134103340 Common menD 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxy late synthase/2-oxoglutarate decarboxylase SACE_6913 89 COG1165 MenD, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase Coenzyme metabolism 134099954 Common - hypothetical protein SACE_3415 6 None None None 134103086 Common - acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase SACE_6656 189 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 134101020 Common - choline/carnitine/betaine transporter family protein SACE_4487 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 134099913 Common - hypothetical protein SACE_3374 4 None None None 134102181 Common - transcriptional regulator, IclR family SACE_5732 123 COG1414 IclR, Transcriptional regulator Transcription 134097876 Nonpathogen - hypothetical protein SACE_1289 1 None None None 134100580 Common - luciferase-like monooxygenase SACE_4045 113 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 134100649 Common - alpha/beta hydrolase fold SACE_4115 158 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134101963 Nonpathogen - hypothetical protein SACE_5481 1 None None None 134101564 Common - 3-hydroxyacyl-CoA dehydrogenase, NAD-binding SACE_5040 149 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 134103008 Common cdd cytidine deaminase SACE_6576 109 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 134102541 Common - large Ala/Glu-rich protein SACE_6104 24 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 134100376 Nonpathogen - hypothetical protein SACE_3841 7 COG0316 IscA, Uncharacterized conserved protein Function unknown 134102535 Nonpathogen - hypothetical protein SACE_6098 1 None None None 134097179 Common moaA molybdenum cofactor biosynthesis protein A SACE_0569 197 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 134102314 Common mraW S-adenosyl-methyltransferase SACE_5866 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 134099760 Common - SUA5/YciO/YrdC/YwlC family protein SACE_3221 211 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 134103374 Common - redox-sensing transcriptional repressor Rex SACE_6947 56 COG2344 COG2344, AT-rich DNA-binding protein General function prediction only 134099934 Common - hypothetical protein SACE_3395 2 None None None 134100893 Common - hydroxymethylglutaryl-CoA lyase SACE_4360 168 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 134100784 Nonpathogen - hypothetical protein SACE_4251 4 COG4762 COG4762, Uncharacterized protein conserved in bacteria Function unknown 134103024 Nonpathogen - hypothetical protein SACE_6593 1 None None None 134102481 Common - magnesium chelatase family protein SACE_6044 189 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 134100682 Common - probable amino acid transporter, APC superfamily SACE_4149 71 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 134101641 Common - serine/threonine protein kinase SACE_5131 75 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 134098538 Nonpathogen - hypothetical protein SACE_1964 1 None None None 134101520 Common - alcohol dehydrogenase, zinc-binding SACE_4992 165 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 134101527 Common - glycosyl hydrolase family 98, putative carbohydrate binding module SACE_4999 10 None None None 134102052 Common - hydrolase, haloacid dehalogenase-like family SACE_5602 106 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 134098844 Common - phosphotransferase system, fructose IIC component SACE_2275 67 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 134102789 Common - glycerophosphoryl diester phosphodiesterase SACE_6355 132 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 134098024 Common - hypothetical protein SACE_1438 22 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 134097079 Nonpathogen - hypothetical protein SACE_0465a 1 None None None 134098227 Nonpathogen - protein of unknown function DUF402 SACE_1644 5 COG2306 COG2306, Uncharacterized conserved protein Function unknown 134098258 Nonpathogen - hypothetical protein SACE_1675 1 None None None 134100696 Common adh1 zinc-binding dehydrogenase SACE_4163 205 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 134101050 Common - UspA domain protein SACE_4517 17 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 134103786 Common - sensor kinase, two-component system SACE_7366 61 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 134099923 Common - caffeoyl O-methyltransferase (partial match) SACE_3384 95 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 134101973 Common - integral membrane protein SACE_5517 7 None None None 134102937 Common - oxidoreductase SACE_6504 62 COG0778 NfnB, Nitroreductase Energy production and conversion 134100927 Common menG S-adenosylmethionine: 2-demethylmenaquinone methyltransferase protein SACE_4394 39 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 134101716 Common idsA2 geranylgeranyl pyrophosphate synthase SACE_5211 239 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 134099001 Common pvdS1 RNA polymerase sigma factor, putative SACE_2439 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 134101245 Common mutM formamidopyrimidine-DNA glycosylase SACE_4713 179 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 134099971 Common - ribosomal RNA adenine dimethylase domain protein SACE_3432 38 COG3963 COG3963, Phospholipid N-methyltransferase Lipid metabolism 134099950 Nonpathogen - hypothetical protein SACE_3411 1 None None None 134099644 Nonpathogen - hypothetical protein SACE_3102 5 COG4995 COG4995, Uncharacterized protein conserved in bacteria Function unknown 134103229 Common truA tRNA pseudouridine synthase A SACE_6801 231 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 134100352 Common - sugar-binding transcriptional regulator, LacI family SACE_3817 127 COG1609 PurR, Transcriptional regulators Transcription 134099055 Nonpathogen - hypothetical protein SACE_2498 1 COG5416 COG5416, Uncharacterized integral membrane protein Function unknown 134101144 Common - LysR-family trancsriptional regulator SACE_4611 21 COG0583 LysR, Transcriptional regulator Transcription 134099320 Common - alpha/beta hydrolase domain protein SACE_2775 57 COG0657 Aes, Esterase/lipase Lipid metabolism 134099897 Common gntP gluconate permease SACE_3358 79 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 134100689 Nonpathogen - integral membrane protein SACE_4156 1 None None None 134096809 Nonpathogen - hypothetical protein SACE_0192 2 None None None 134099307 Common - NADH:flavin oxidoreductase/NADH oxidase SACE_2762 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 134100498 Common - hypothetical protein SACE_3963 14 COG0431 COG0431, Predicted flavoprotein General function prediction only 134098796 Common - hypothetical protein SACE_2227 115 COG1733 COG1733, Predicted transcriptional regulators Transcription 134103803 Common - hypothetical protein SACE_7383 3 None None None 134103252 Common rplE 50S ribosomal protein L5 SACE_6824 245 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 134098376 Nonpathogen - secreted protein SACE_1796 3 None None None 134102498 Common glnB nitrogen regulatory protein PII SACE_6061 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 134102571 Common - hypothetical protein SACE_6134 10 None None None 134099902 Common - transcriptional regulator SACE_3363 45 COG2378 COG2378, Predicted transcriptional regulator Transcription 134100718 Common - hypothetical protein SACE_4185 90 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 134103040 Common - heavy metal transport/detoxification protein SACE_6610 13 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 134102448 Common - hypothetical protein SACE_6004 13 None None None 134103215 Nonpathogen - PE-PGRS family protein SACE_6786 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 134099704 Common - secreted protein SACE_3164 8 None None None 134097765 Nonpathogen - hypothetical protein SACE_1173 1 None None None 134097016 Nonpathogen - hypothetical protein SACE_0403 1 None None None 134102765 Common - putative fusion protein (ligase/carboxylase and argininosuccinate lyase SACE_6330 41 COG0439 AccC, Biotin carboxylase Lipid metabolism 134102901 Common - NUDIX hydrolase SACE_6468 14 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 134102214 Nonpathogen - secreted protein SACE_5765 3 None None None 134103016 Common sdhB succinate dehydrogenase iron-sulfur subunit SACE_6585 207 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 134102229 Common - carboxypeptidase SACE_5780 20 COG2866 COG2866, Predicted carboxypeptidase Amino acid transport and metabolism 134097588 Common - oligopeptide/dipeptide ABC transporter, permease protein SACE_0992 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 134103669 Common - N-ethylammeline chlorohydrolase SACE_7247 170 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 134099991 Common - alpha/beta hydrolase fold SACE_3453 33 COG2267 PldB, Lysophospholipase Lipid metabolism 134096936 Nonpathogen - hypothetical protein SACE_0322 2 COG3115 ZipA, Cell division protein Cell division and chromosome partitioning 134102862 Common - biotin/lipoyl attachment SACE_6428 121 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 134102491 Common - probable conserved integral membrane protein SACE_6054 25 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 134097510 Common - hypothetical protein SACE_0912 2 None None None 134098866 Nonpathogen - hypothetical protein SACE_2300 2 None None None 134101593 Common - probable Na(+)/glutamate:H(+) symporter SACE_5070 157 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 134100367 Common - protein of unknown function DUF21 SACE_3832 217 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 134100972 Common - transcriptional regulator, LacI family SACE_4439 126 COG1609 PurR, Transcriptional regulators Transcription 134101799 Common - feruloyl esterase SACE_5296 51 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 134102295 Common - transcriptional regulator, XRE family SACE_5847 6 None None None 134103188 Common - stearoyl-CoA 9-desaturase SACE_6758 69 COG1398 OLE1, Fatty-acid desaturase Lipid metabolism 134102450 Common - hypothetical protein SACE_6006 3 None None None 134101367 Common - hypothetical protein SACE_4838 100 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 134099588 Common - manganese catalase SACE_3046 46 COG3546 COG3546, Mn-containing catalase Inorganic ion transport and metabolism 134103357 Common ccsB cytochrome c assembly membrane protein SACE_6930 83 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 134098937 Nonpathogen - hypothetical protein SACE_2373 1 None None None 134101348 Common - transcriptional regulator, TetR family SACE_4819 41 COG1309 AcrR, Transcriptional regulator Transcription 134099720 Common - glycosyl transferase, group 1 SACE_3180 29 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 134103323 Common nuoH NADH dehydrogenase subunit H SACE_6895 184 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 134097324 Common eryCVI TDP-desosamine-N-dimethyltransferase SACE_0718 85 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134098650 Common pyrB aspartate carbamoyltransferase catalytic chain SACE_2079 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 134101830 Common - Na+/H+ antiporter homolog SACE_5327 22 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 134103239 Common - peptidase M24A, methionine aminopeptidase,subfamily 1 SACE_6811 236 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 134100834 Common - glucose-methanol-choline oxidoreductase SACE_4301 63 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 134097604 Common - putative N-acetylglucosaminylphosphatidylinositol deacetylase SACE_1008 32 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 134099787 Common - secreted oxidoreductase SACE_3248 125 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 134102860 Common whiB1 putative transcriptional regulator (WhiB family) SACE_6426 19 None None None 134100062 Common - drug resistance transporter, EmrB/QacA family SACE_3524 199 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 134098017 Common - hypothetical protein SACE_1431 17 COG1434 COG1434, Uncharacterized conserved protein Function unknown 134098576 Common - protein of unknown function DUF574 SACE_2002 13 None None None 134099593 Common - metallo-beta-lactamase-like protein SACE_3051 64 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 134098245 Nonpathogen - hypothetical protein SACE_1662 1 None None None 134102858 Common - probable conserved integral membrane protein SACE_6424 5 None None None 134099172 Common - transposase SACE_2624 21 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134099690 Common - probable hydroxyacylglutathione hydrolase SACE_3148 209 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 134101505 Nonpathogen - hypothetical protein SACE_4977 1 None None None 134102464 Common - predicted Fe-S-cluster redox enzyme SACE_6026 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 134098016 Nonpathogen - hypothetical protein SACE_1430 1 None None None 134098112 Common fabD [acyl-carrier protein] S-malonyltransferase SACE_1526 205 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 134098025 Common rpsT 30S ribosomal protein S20 SACE_1439 198 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 134099421 Common - TetR-family transcriptional regulator SACE_2879 26 COG1309 AcrR, Transcriptional regulator Transcription 134101897 Common - hypothetical protein SACE_5395 5 None None None 134098837 Common - transcriptional regulator, TetR family SACE_2268 88 COG1309 AcrR, Transcriptional regulator Transcription 134101608 Common - hypothetical protein SACE_5087 87 COG1204 COG1204, Superfamily II helicase General function prediction only 134098121 Common - putative zinc-type alcohol dehydrogenase transmembrane protein SACE_1535 198 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 134103359 Common ccdA cytochrome c-type biogenesis protein SACE_6932 81 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 134099105 Nonpathogen - hypothetical protein SACE_2550 1 None None None 134097861 Common - putative lysyl tRNA synthetase-like protein SACE_1272 17 None None None 134098659 Common - putative cytoplasmic protein SACE_2088 10 None None None 134101412 Common - ABC transporter permease protein SACE_4882 147 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 134100475 Common - putative pirin-like protein SACE_3940 132 COG1741 COG1741, Pirin-related protein General function prediction only 134102992 Common - transcriptional regulatory protein SACE_6560 40 COG1309 AcrR, Transcriptional regulator Transcription 134099275 Common - hypothetical protein SACE_2730 10 None None None 134098849 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase SACE_2281 71 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 134096988 Common hppA membrane-bound proton-translocating pyrophosphatase SACE_0375 98 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 134102959 Common lpdA flavoprotein disulfide reductase SACE_6526 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 134096892 Nonpathogen - hypothetical protein SACE_0278 2 None None None 134099121 Common - transposase for IS3513 SACE_2566 132 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 134103605 Common nagC4 transcriptional regulator SACE_7183 125 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 134097664 Common - transcriptional regulator, TetR family SACE_1068 54 COG1309 AcrR, Transcriptional regulator Transcription 134096852 Common - putative large secreted protein SACE_0235 48 COG2374 COG2374, Predicted extracellular nuclease General function prediction only 134096746 Common - RNA polymerase ECF sigma factor SACE_0128 109 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 134103057 Common - two-component system sensor kinase SACE_6627 36 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 134103612 Common - short-chain dehydrogenase/reductase SDR SACE_7190 238 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 134098044 Common echA9 putative enoyl-CoA hydratase/isomerase SACE_1458 168 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 134098073 Common era GTP-binding protein Era SACE_1487 217 COG1159 Era, GTPase General function prediction only 134096697 Common - probable ABC quaternary amine transporter,permease component SACE_0079 138 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 134098623 Common - Holliday junction resolvase YqgF SACE_2053 99 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 134097581 Nonpathogen - hypothetical protein SACE_0985 1 None None None 134098805 Common - homoserine dehydrogenase SACE_2236 190 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 134103222 Common mycP1 putative serine protease SACE_6794 105 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 134097304 Common - transcriptional regulator, ArsR family SACE_0697 41 COG0640 ArsR, Predicted transcriptional regulators Transcription 134100099 Common - molybdopterin oxidoreductase Fe4s4 region SACE_3561 155 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 134098857 Common - dolichyl-phosphate beta-D-mannosyltransferase SACE_2289 205 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 134102185 Common embA arabinosyl transferase SACE_5736 5 None None None 134101172 Nonpathogen - hypothetical protein-signal peptide prediction SACE_4639 2 None None None 134099541 Common - transposase SACE_2999 64 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 134099250 Common pip proline iminopeptidase SACE_2704 98 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 134096788 Nonpathogen - hypothetical protein SACE_0171 1 None None None 134098415 Common - putative maleate cis-trans isomerase SACE_1839 26 COG3473 COG3473, Maleate cis-trans isomerase Secondary metabolites biosynthesis, transport, and catabolism 134098916 Common - transposase, IS111A/IS1328/IS1533 SACE_2352 76 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 134100604 Common narH nitrate reductase beta chain SACE_4069 145 COG1140 NarY, Nitrate reductase beta subunit Energy production and conversion 134103315 Common - hypothetical protein SACE_6887 5 None None None 134098519 Common - D-isomer specific 2-hydroxyacid dehydrogenase family protein SACE_1944 230 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 134098514 Common - putative cyclase SACE_1939 83 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 134097645 Common - secreted trypsin-like serine protease SACE_1049 59 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 134101715 Common idi isopentenyl-diphosphate delta-isomerase SACE_5210 48 COG1443 Idi, Isopentenyldiphosphate isomerase Lipid metabolism 134103245 Common rplO 50S ribosomal protein L15 SACE_6817 193 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 134098527 Common - peptidase E SACE_1952 31 COG3340 PepE, Peptidase E Amino acid transport and metabolism 134099194 Common - 4-aminobutyrate aminotransferase class-III SACE_2647 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 134098748 Common - SUF system FeS assembly protein SACE_2178 162 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 134102566 Common - hypothetical protein SACE_6129 6 None None None 134098725 Common devB 6-phosphogluconolactonase SACE_2155 115 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 134098295 Common crtI phytoene desaturase SACE_1713 74 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 134101364 Common - hypothetical protein SACE_4835 5 COG1279 COG1279, Lysine efflux permease General function prediction only 134097544 Nonpathogen - hypothetical protein SACE_0946 1 None None None 134101782 Common rplT 50S ribosomal protein L20 SACE_5279 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 134101105 Common - polyketide biosynthesis enoyl-CoA hydratase SACE_4572 140 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 134101943 Common degU two-component response regulator SACE_5445 118 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 134103001 Nonpathogen - hypothetical protein SACE_6569 1 COG4282 SMI1, Protein involved in beta-1,3-glucan synthesis Carbohydrate transport and metabolism 134103352 Nonpathogen - hypothetical protein SACE_6925 1 None None None 134097334 Common eryG erythromycin C methlytransferase SACE_0728 116 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism