Clostridium thermocellum ATCC 27405, complete genome NC_009012 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 125973948 Common - hypothetical protein Cthe_1434 5 None None None 125973890 Common - aspartate kinase Cthe_1375 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 125972799 Common - hypothetical protein Cthe_0277 116 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 125973150 Nonpathogen - hypothetical protein Cthe_0632 1 None None None 125975462 Common - hypothetical protein Cthe_2982 4 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 125973963 Common - hypothetical protein Cthe_1450 5 None None None 125973676 Common - hypothetical protein Cthe_1161 16 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 125974331 Nonpathogen - copper amine oxidase-like protein Cthe_1827 9 None None None 125973798 Common - endonuclease III Cthe_1283 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 125973842 Nonpathogen - hypothetical protein Cthe_1327 1 None None None 125975433 Common - IstB-like ATP-binding protein Cthe_2952 96 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 125972645 Nonpathogen - hypothetical protein Cthe_0121 1 None None None 125974277 Common - peptidase S16, lon-like protein Cthe_1773 159 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 125973280 Common - protein of unknown function DUF1121 Cthe_0762 21 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 125972570 Nonpathogen - hypothetical protein Cthe_0046 2 None None None 125972539 Nonpathogen - hypothetical protein Cthe_0014 1 None None None 125972581 Common - hypothetical protein Cthe_0057 8 None None None 125975699 Nonpathogen - hypothetical protein Cthe_3221 1 None None None 125973613 Nonpathogen - hypothetical protein Cthe_1098 1 None None None 125975633 Common - beta-lactamase-like protein Cthe_3155 107 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 125974041 Common - hypothetical protein Cthe_1531 11 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 125973551 Nonpathogen - hypothetical protein Cthe_1036 2 None None None 125974354 Nonpathogen - hypothetical protein Cthe_1850 7 COG4393 COG4393, Predicted membrane protein Function unknown 125975250 Common - metallophosphoesterase Cthe_2768 115 COG4639 COG4639, Predicted kinase General function prediction only 125974739 Common - hypoxanthine phosphoribosyltransferase Cthe_2254 150 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 125974622 Common - Integrase, catalytic region Cthe_2135 153 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973989 Common - deoxycytidine triphosphate deaminase Cthe_1477 165 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 125975323 Common - hypothetical protein Cthe_2841 3 None None None 125973858 Common - D-tyrosyl-tRNA deacylase Cthe_1343 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 125973659 Common - restriction modification system DNA specificity domain Cthe_1144 58 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 125974755 Common - ABC transporter related protein Cthe_2270 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 125973037 Nonpathogen - hypothetical protein Cthe_0517 4 None None None 125972883 Common - transcriptional regulator, AsnC family Cthe_0362 104 COG1522 Lrp, Transcriptional regulators Transcription 125974764 Common - polar amino acid ABC transporter, inner membrane subunit Cthe_2279 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 125975098 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Cthe_2615 211 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 125973851 Nonpathogen - hypothetical protein Cthe_1336 1 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 125975597 Common - flavin reductase-like, FMN-binding Cthe_3119 61 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 125975227 Nonpathogen - hypothetical protein Cthe_2745 1 None None None 125973391 Common - glutamine amidotransferase of anthranilate synthase Cthe_0874 240 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 125974912 Common - protein of unknown function DUF1385 Cthe_2427 31 COG3872 COG3872, Predicted metal-dependent enzyme General function prediction only 125974593 Common - 4Fe-4S ferredoxin, iron-sulfur binding Cthe_2103 199 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 125974243 Common - SNF2-related protein Cthe_1739 105 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 125975419 Common - putative glucokinase, ROK family Cthe_2938 159 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 125974314 Common - peptidase M56, BlaR1 Cthe_1810 30 COG4219 MecR1, Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component Transcription / Signal transduction mechanisms 125973687 Common - protein of unknown function DUF362 Cthe_1172 36 COG2006 COG2006, Uncharacterized conserved protein Function unknown 125972807 Common - isocitrate dehydrogenase Cthe_0285 78 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 125973218 Common - biotin/lipoyl attachment protein Cthe_0700 210 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 125975573 Common - glycosyl transferase, family 39 Cthe_3095 28 COG4346 COG4346, Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase Posttranslational modification, protein turnover, chaperones 125972896 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein Cthe_0375 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 125974473 Nonpathogen - hypothetical protein Cthe_1972 1 None None None 125973159 Common - Coat F Cthe_0641 6 COG5577 COG5577, Spore coat protein Cell envelope biogenesis, outer membrane 125973649 Nonpathogen - hypothetical protein Cthe_1134 1 None None None 125973933 Nonpathogen - hypothetical protein Cthe_1419 1 None None None 125974788 Nonpathogen - CRISPR-associated protein Cas6 Cthe_2303 24 COG1583 COG1583, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 125975081 Common - uracil phosphoribosyltransferase Cthe_2598 164 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 125973692 Common - nicotinate phosphoribosyltransferase Cthe_1177 111 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 125974108 Common - multi-sensor signal transduction histidine kinase Cthe_1599 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 125973381 Common - pyruvate ferredoxin/flavodoxin oxidoreductase Cthe_0864 72 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 125972823 Common - hypothetical protein Cthe_0302 26 COG3610 COG3610, Uncharacterized conserved protein Function unknown 125974305 Common - ABC transporter related protein Cthe_1801 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 125975703 Nonpathogen - hypothetical protein Cthe_3225 1 None None None 125973032 Common - phage integrase Cthe_0512 184 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 125974587 Common - hypothetical protein Cthe_2097 7 None None None 125974134 Common - uncharacterized phage protein Cthe_1627 7 None None None 125973893 Common - response regulator receiver modulated metal dependent phosphohydrolase Cthe_1378 166 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 125975558 Common - cellulosome anchoring protein, cohesin region Cthe_3079 24 COG3889 COG3889, Predicted solute binding protein General function prediction only 125975347 Common - phage major capsid protein, HK97 Cthe_2866 14 COG4653 COG4653, Predicted phage phi-C31 gp36 major capsid-like protein General function prediction only 125973913 Common - C_GCAxxG_C_C family protein Cthe_1399 18 None None None 125974704 Common - flagellar protein FlaG protein Cthe_2219 15 COG1334 FlaG, Uncharacterized flagellar protein FlaG Cell motility and secretion 125973869 Nonpathogen - O-antigen polymerase Cthe_1354 2 None None None 125975259 Common - nicotinamide mononucleotide transporter PnuC Cthe_2777 52 COG3201 PnuC, Nicotinamide mononucleotide transporter Coenzyme metabolism 125974501 Common - transposase IS3/IS911 Cthe_2001 39 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973589 Common - polysaccharide deacetylase Cthe_1074 113 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 125972533 Common - hypothetical protein Cthe_0008 3 None None None 125975469 Common - peptide methionine sulfoxide reductase Cthe_2990 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 125972939 Common - polynucleotide phosphorylase/polyadenylase Cthe_0418 240 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 125973145 Nonpathogen - hypothetical protein Cthe_0627 1 None None None 125974896 Common - metallophosphoesterase Cthe_2411 87 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 125974778 Nonpathogen - hypothetical protein Cthe_2293 1 None None None 125975687 Common - hypothetical protein Cthe_3209 12 COG1353 COG1353, Predicted hydrolase of the HD superfamily (permuted catalytic motifs) General function prediction only 125973644 Common - hypothetical protein Cthe_1129 3 None None None 125975178 Common - carbohydrate kinase, YjeF related protein Cthe_2696 222 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 125973668 Common - diguanylate cyclase Cthe_1153 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 125973290 Nonpathogen - Peptidoglycan-binding LysM Cthe_0772 1 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 125973549 Nonpathogen - hypothetical protein Cthe_1034 1 None None None 125973472 Common - hypothetical protein Cthe_0955 5 None None None 125974781 Common - CRISPR-associated protein Cas2 Cthe_2296 38 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 125973123 Common - NLP/P60 Cthe_0605 138 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 125973187 Common - spore germination B3 GerAC like Cthe_0669 15 None None None 125974206 Common - cell wall hydrolase/autolysin Cthe_1702 116 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 125973315 Common - glycoside hydrolase, family 5 Cthe_0797 24 COG2730 BglC, Endoglucanase Carbohydrate transport and metabolism 125974095 Common - binding-protein-dependent transport systems inner membrane component Cthe_1586 220 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 125974164 Common - potassium uptake protein, TrkH family Cthe_1658 122 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 125975670 Nonpathogen - hypothetical protein Cthe_3192 1 None None None 125973385 Nonpathogen - type IV pilus assembly PilZ Cthe_0868 1 None None None 125973569 Common - ATPase associated with various cellular activities, AAA_3 Cthe_1054 177 COG0714 COG0714, MoxR-like ATPases General function prediction only 125973508 Common - protein of unknown function DUF448 Cthe_0993 50 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 125974819 Common - polysaccharide biosynthesis protein CapD Cthe_2334 221 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 125974300 Common - Prephenate dehydrogenase Cthe_1796 154 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 125975215 Nonpathogen - hypothetical protein Cthe_2733 1 None None None 125973990 Common - transcriptional regulator, TetR family Cthe_1478 15 COG1309 AcrR, Transcriptional regulator Transcription 125973057 Common - periplasmic sensor signal transduction histidine kinase Cthe_0538 220 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 125975442 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Cthe_2962 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 125973920 Common - hypothetical protein Cthe_1406 17 COG1285 SapB, Uncharacterized membrane protein Function unknown 125972752 Nonpathogen - hypothetical protein Cthe_0230 2 None None None 125973050 Nonpathogen - hypothetical protein Cthe_0531 1 None None None 125973501 Common - peptidase M16-like protein Cthe_0986 110 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 125974541 Nonpathogen - CRISPR-associated RAMP protein, SSO1426 family Cthe_2051 32 COG1337 COG1337, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 125974056 Common - 4Fe-4S ferredoxin, iron-sulfur binding Cthe_1546 36 COG2768 COG2768, Uncharacterized Fe-S center protein General function prediction only 125974083 Nonpathogen - hypothetical protein Cthe_1574 1 None None None 125975067 Nonpathogen - hypothetical protein Cthe_2584 2 None None None 125973904 Common - metal dependent phosphohydrolase Cthe_1389 213 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 125974155 Common - BRO-like protein Cthe_1649 31 COG3617 COG3617, Prophage antirepressor Transcription 125975230 Common smpB SsrA-binding protein Cthe_2748 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 125973343 Common - glycoside hydrolase, family 9 Cthe_0825 21 None None None 125974077 Common - Radical SAM Cthe_1568 71 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 125974733 Common - phosphoribosyltransferase Cthe_2248 171 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 125974659 Common - transcription termination factor Rho Cthe_2174 208 COG1158 Rho, Transcription termination factor Transcription 125972759 Common - response regulator receiver protein Cthe_0237 194 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 125972932 Nonpathogen - hypothetical protein Cthe_0411 1 None None None 125972698 Common - sulfatase Cthe_0174 75 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 125973311 Nonpathogen - hypothetical protein Cthe_0793 3 None None None 125974406 Common - amino acid adenylation domain Cthe_1904 227 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 125974198 Nonpathogen - hypothetical protein Cthe_1693 1 None None None 125973531 Common - cell wall hydrolase/autolysin Cthe_1016 183 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 125973950 Common - hypothetical protein Cthe_1437 9 None None None 125975679 Common - CRISPR-associated protein, Csh1 family Cthe_3201 11 None None None 125973503 Common - tRNA pseudouridine synthase B Cthe_0988 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 125973765 Common - phosphoribosylaminoimidazole carboxylase, catalytic subunit Cthe_1250 233 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 125974424 Common - hypothetical protein Cthe_1922 8 None None None 125975399 Common - ribosomal protein L6 Cthe_2918 242 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 125973423 Common - Radical SAM Cthe_0906 112 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 125975556 Common - cellulosome anchoring protein, cohesin region Cthe_3077 9 None None None 125973173 Common - cysteine desulfurase family protein Cthe_0655 242 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 125972961 Common - Domain of unknown function DUF1727 Cthe_0440 47 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 125975133 Nonpathogen - hypothetical protein Cthe_2651 1 None None None 125973386 Common - hypothetical protein Cthe_0869 15 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 125973139 Common - putative translation initiation factor, aIF-2BI family Cthe_0621 132 COG0182 COG0182, Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 125973224 Common - transcriptional regulator, RpiR family Cthe_0706 96 COG1737 RpiR, Transcriptional regulators Transcription 125974933 Common - inner-membrane translocator Cthe_2448 115 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 125973061 Common - protein of unknown function DUF45 Cthe_0542 153 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 125973886 Common - YD repeat protein Cthe_1371 78 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 125973607 Common - hypothetical protein Cthe_1092 14 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 125973432 Common - hypothetical protein Cthe_0915 2 None None None 125974651 Common - putative PAS/PAC sensor protein Cthe_2166 115 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 125975680 Common - CRISPR-associated protein, Csh2 family Cthe_3202 56 COG3649 COG3649, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 125972914 Common - sugar ABC transporter (sugar-binding protein) Cthe_0393 87 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 125973860 Common - adenine phosphoribosyltransferase Cthe_1345 190 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 125974718 Common - protein of unknown function DUF115 Cthe_2233 27 COG2604 COG2604, Uncharacterized protein conserved in bacteria Function unknown 125973827 Common - glycyl-tRNA synthetase Cthe_1312 88 COG0423 GRS1, Glycyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 125974992 Common - peptidase U57, YabG Cthe_2507 11 None None None 125974065 Common - binding-protein-dependent transport systems inner membrane component Cthe_1556 127 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 125974213 Common - Phage-related protein-like protein Cthe_1709 26 COG5412 COG5412, Phage-related protein Function unknown 125975541 Common - signal transduction histidine kinase regulating citrate/malate metabolism Cthe_3062 49 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 125972577 Common - ribonucleotide-diphosphate reductase subunit alpha Cthe_0053 224 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 125975477 Common - ABC transporter related protein Cthe_2998 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 125972705 Common - Holliday junction DNA helicase RuvA Cthe_0181 211 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 125974548 Common - Appr-1-p processing protein Cthe_2058 116 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 125973259 Common - adenylosuccinate lyase Cthe_0741 171 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 125974821 Common - glycosyl transferase, group 1 Cthe_2336 88 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 125973755 Common - metal dependent phosphohydrolase Cthe_1240 43 COG1713 COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism Coenzyme metabolism 125975238 Common - transposase Cthe_2756 53 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 125972741 Common - Glucose-6-phosphate isomerase Cthe_0217 206 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 125973739 Common - ribosomal protein L35 Cthe_1224 204 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 125973104 Common - Integrase, catalytic region Cthe_0585 153 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 125975284 Common - NLPA lipoprotein Cthe_2802 108 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 125974642 Nonpathogen - hypothetical protein Cthe_2156 1 None None None 125972965 Common - cell division protein FtsA Cthe_0444 186 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 125973188 Common - spore germination protein Cthe_0670 15 None None None 125973202 Common - Polynucleotide adenylyltransferase region Cthe_0684 241 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 125973760 Common - phosphoribosylamine--glycine ligase Cthe_1245 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 125975453 Common - sugar fermentation stimulation protein Cthe_2973 109 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 125974603 Common - periplasmic sensor signal transduction histidine kinase Cthe_2113 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 125974185 Common - Methyltransferase type 11 Cthe_1679 108 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 125974942 Common - hypothetical protein Cthe_2457 9 None None None 125974191 Common - transposase IS3/IS911 Cthe_1686 39 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973352 Common - NusB antitermination factor Cthe_0834 197 COG0781 NusB, Transcription termination factor Transcription 125972797 Common - glycosyltransferase 36 Cthe_0275 45 COG3459 COG3459, Cellobiose phosphorylase Carbohydrate transport and metabolism 125973540 Common - protein of unknown function DUF512 Cthe_1025 31 COG1625 COG1625, Fe-S oxidoreductase, related to NifB/MoaA family Energy production and conversion 125975343 Nonpathogen - hypothetical protein Cthe_2862 1 None None None 125973305 Common ileS isoleucyl-tRNA synthetase Cthe_0787 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 125975247 Common - hypothetical protein Cthe_2765 3 None None None 125973336 Nonpathogen - hypothetical protein Cthe_0818 1 None None None 125972981 Common - DNA topoisomerase I Cthe_0460 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 125974103 Common - hypothetical protein Cthe_1594 2 None None None 125973510 Common - protein of unknown function DUF150 Cthe_0995 178 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 125975516 Common - nitroreductase Cthe_3037 45 COG0778 NfnB, Nitroreductase Energy production and conversion 125973465 Common - oxidoreductase FAD/NAD(P)-binding Cthe_0948 113 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 125973878 Common - lipopolysaccharide biosynthesis Cthe_1363 203 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 125972925 Common - type 3a, cellulose-binding Cthe_0404 17 COG5373 COG5373, Predicted membrane protein Function unknown 125973821 Nonpathogen - hypothetical protein Cthe_1306 1 None None None 125974798 Common - protein of unknown function DUF218 Cthe_2313 114 COG1434 COG1434, Uncharacterized conserved protein Function unknown 125974063 Common - methylated-DNA--protein-cysteine methyltransferase Cthe_1554 210 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 125974269 Common - hypothetical protein Cthe_1765 6 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 125974145 Common - DNA methylase N-4/N-6 Cthe_1639 85 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 125975315 Nonpathogen - hypothetical protein Cthe_2833 1 None None None 125973498 Common - cell cycle protein Cthe_0983 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 125975532 Nonpathogen - hypothetical protein Cthe_3053 2 None None None 125974857 Common - DNA polymerase III subunit beta Cthe_2372 216 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 125975198 Common - Integrase, catalytic region Cthe_2716 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 125974632 Common - copper amine oxidase-like protein Cthe_2146 10 None None None 125973781 Common - methyl-accepting chemotaxis sensory transducer Cthe_1266 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 125975194 Nonpathogen - hypothetical protein Cthe_2712 3 None None None 125974355 Common - protein of unknown function DUF1113 Cthe_1851 12 COG4905 COG4905, Predicted membrane protein Function unknown 125974124 Common - phage putative tail component Cthe_1617 7 COG4722 COG4722, Phage-related protein Function unknown 125973234 Common - Nucleoside-diphosphate kinase Cthe_0716 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 125972854 Common - hypothetical protein Cthe_0333 8 COG4109 COG4109, Predicted transcriptional regulator containing CBS domains Transcription 125973451 Common - 3-oxoacyl-(acyl-carrier-protein) reductase Cthe_0934 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 125973776 Common - 6-phosphofructokinase Cthe_1261 160 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 125974828 Common - GCN5-related N-acetyltransferase Cthe_2343 9 COG0456 RimI, Acetyltransferases General function prediction only 125974554 Common - spore germination B3 GerAC like Cthe_2064 15 None None None 125972541 Common - Ferritin and Dps Cthe_0016 84 COG1528 Ftn, Ferritin-like protein Inorganic ion transport and metabolism 125974644 Common - hypothetical protein Cthe_2159 11 None None None 125974010 Common - ammonium transporter Cthe_1499 210 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 125972649 Common - stage V sporulation AE Cthe_0125 7 None None None 125974709 Common - putative methionyl-tRNA formyltransferase Cthe_2224 68 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 125975551 Common - acyl-ACP thioesterase Cthe_3072 24 COG3884 FatA, Acyl-ACP thioesterase Lipid metabolism 125972714 Common - proteinase inhibitor I4, serpin Cthe_0190 31 COG4826 COG4826, Serine protease inhibitor Posttranslational modification, protein turnover, chaperones 125972992 Common - flagellar hook-length control protein Cthe_0471 29 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 125973685 Common - Dihydrodipicolinate reductase Cthe_1170 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 125972879 Common - hypothetical protein Cthe_0358 1 None None None 125973355 Common - protein of unknown function DUF322 Cthe_0837 41 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 125973397 Common - phospho-2-dehydro-3-deoxyheptonate aldolase Cthe_0880 186 COG2876 AroA, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 125972971 Common - hypothetical protein Cthe_0450 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 125975088 Common - ATP synthase F1, delta subunit Cthe_2605 171 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 125975371 Common - putative transcriptional regulator Cthe_2890 65 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 125974583 Common - hypothetical protein Cthe_2093 32 COG3583 COG3583, Uncharacterized protein conserved in bacteria Function unknown 125973328 Common - CheA signal transduction histidine kinases Cthe_0810 159 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 125973000 Common - response regulator receiver protein Cthe_0479 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 125975144 Common - RNA binding S1 Cthe_2662 241 COG1098 VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) Translation, ribosomal structure and biogenesis 125974113 Common - phosphate ABC transporter, inner membrane subunit PstC Cthe_1604 227 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 125972588 Common - Na/Pi-cotransporter II-related protein Cthe_0064 89 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 125975022 Common - sulfate adenylyltransferase, large subunit Cthe_2537 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 125975389 Common - ribosomal protein L22 Cthe_2908 227 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 125975491 Common - Carbohydrate binding family 6 Cthe_3012 18 COG5520 COG5520, O-Glycosyl hydrolase Cell envelope biogenesis, outer membrane 125974698 Common - hypothetical protein Cthe_2213 23 COG4843 COG4843, Uncharacterized protein conserved in bacteria Function unknown 125975587 Common - Uracil-DNA glycosylase superfamily Cthe_3109 147 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 125975110 Common - SpoVG Cthe_2628 24 COG2088 SpoVG, Uncharacterized protein, involved in the regulation of septum location Cell envelope biogenesis, outer membrane 125974366 Common - ABC transporter related protein Cthe_1862 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 125975270 Common - hypothetical protein Cthe_2788 16 COG4887 COG4887, Uncharacterized metal-binding protein conserved in archaea General function prediction only 125975253 Common - beta-lactamase-like protein Cthe_2771 84 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 125972658 Common - hypothetical protein Cthe_0134 7 COG2267 PldB, Lysophospholipase Lipid metabolism 125974664 Common - Pectate lyase/Amb allergen Cthe_2179 29 COG3866 PelB, Pectate lyase Carbohydrate transport and metabolism 125974611 Nonpathogen - hypothetical protein Cthe_2121 1 None None None 125975427 Common ispF 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Cthe_2946 179 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 125973957 Common - GCN5-related N-acetyltransferase Cthe_1444 68 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 125973252 Common - peptidase M23B Cthe_0734 193 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 125975420 Common truA tRNA pseudouridine synthase A Cthe_2939 237 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 125974512 Common - transposase, mutator type Cthe_2017 88 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 125972783 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Cthe_0261 202 COG0546 Gph, Predicted phosphatases General function prediction only 125974494 Nonpathogen - hypothetical protein Cthe_1994 2 None None None 125972666 Common - metal dependent phosphohydrolase Cthe_0142 179 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 125972788 Common - methyl-accepting chemotaxis sensory transducer Cthe_0266 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 125973278 Common - hypothetical protein Cthe_0760 7 COG3889 COG3889, Predicted solute binding protein General function prediction only 125973148 Nonpathogen - hypothetical protein Cthe_0630 1 None None None 125973262 Common - copper amine oxidase-like protein Cthe_0744 163 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 125973708 Common - transposase, mutator type Cthe_1193 89 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 125975522 Common - hypothetical protein Cthe_3043 11 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 125972655 Common - hypothetical protein Cthe_0131 28 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 125972634 Common - HPr kinase Cthe_0110 77 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 125974665 Common - Cl- channel, voltage gated Cthe_2180 155 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 125975071 Common - pantothenate kinase Cthe_2588 140 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 125972604 Common - CheW protein Cthe_0080 106 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 125973375 Common - protein of unknown function DUF1432 Cthe_0858 18 COG4864 COG4864, Uncharacterized protein conserved in bacteria Function unknown 125973126 Common - peptidase M42 Cthe_0608 77 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 125974964 Common - Lj928 prophage protein Cthe_2479 4 None None None 125973536 Common - stage IV sporulation protein A Cthe_1021 15 None None None 125974628 Common - metal-dependent phosphohydrolase, HD subdomain Cthe_2141 153 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 125973271 Nonpathogen - hypothetical protein Cthe_0753 1 None None None 125974855 Common - ribosomal protein L34 Cthe_2370 3 None None None 125974907 Nonpathogen - hypothetical protein Cthe_2422 1 None None None 125975436 Nonpathogen - hypothetical protein Cthe_2955 4 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 125973935 Common - signal peptide peptidase SppA, 36K type Cthe_1421 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 125973094 Common - ribosome small subunit-dependent GTPase A Cthe_0575 164 COG1162 COG1162, Predicted GTPases General function prediction only 125975501 Common - NADH ubiquinone oxidoreductase, 20 kDa subunit Cthe_3022 192 COG3260 COG3260, Ni,Fe-hydrogenase III small subunit Energy production and conversion 125975450 Common - ABC transporter related protein Cthe_2970 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 125974283 Nonpathogen - hypothetical protein Cthe_1779 1 None None None 125973421 Common - protein-export membrane protein SecD Cthe_0904 224 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 125972872 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Cthe_0351 85 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 125972857 Common - DRTGG domain containing protein Cthe_0336 8 COG0857 Pta, BioD-like N-terminal domain of phosphotransacetylase General function prediction only 125972999 Common - flagellar motor switch protein Cthe_0478 131 COG1776 CheC, Chemotaxis protein CheC, inhibitor of MCP methylation Cell motility and secretion / Signal transduction mechanisms 125974262 Common - protein of unknown function DUF583 Cthe_1758 86 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 125975328 Nonpathogen - hypothetical protein Cthe_2846 1 None None None 125973134 Common - amino acid-binding ACT Cthe_0616 40 COG4747 COG4747, ACT domain-containing protein General function prediction only 125973048 Nonpathogen - hypothetical protein Cthe_0528 1 None None None 125972557 Common - small GTP-binding protein Cthe_0033 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 125973922 Common - two component transcriptional regulator, winged helix family Cthe_1408 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 125974671 Common - single-strand binding protein Cthe_2186 214 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 125975305 Nonpathogen - hypothetical protein Cthe_2823 1 None None None 125974215 Common - hypothetical protein Cthe_1711 4 None None None 125972920 Common - protein of unknown function DUF477 Cthe_0399 8 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 125973740 Common - translation initiation factor IF-3 Cthe_1225 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 125973638 Common - hypothetical protein Cthe_1123 17 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 125973448 Common - Ribonuclease III Cthe_0931 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 125972637 Common - hypothetical protein Cthe_0113 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 125974711 Common - FkbH like protein Cthe_2226 31 COG3882 FkbH, Predicted enzyme involved in methoxymalonyl-ACP biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 125972615 Common - Peptidoglycan glycosyltransferase Cthe_0091 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 125974502 Nonpathogen - hypothetical protein Cthe_2002 1 None None None 125972692 Nonpathogen - hypothetical protein Cthe_0168 1 None None None 125973745 Common - competence protein ComEA helix-hairpin-helix repeat protein Cthe_1230 110 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 125975166 Nonpathogen - hypothetical protein Cthe_2684 1 None None None 125973621 Common - twitching motility protein Cthe_1106 173 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 125973654 Nonpathogen - hypothetical protein Cthe_1139 1 None None None 125974833 Common - Ig-related protein Cthe_2348 12 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 125975384 Common - ribosomal protein L3 Cthe_2903 246 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 125973325 Common - response regulator receiver modulated CheB methylesterase Cthe_0807 192 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 125974807 Common - DNA recombinase Cthe_2322 3 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 125974574 Nonpathogen - hypothetical protein Cthe_2084 1 None None None 125975296 Common - periplasmic sensor signal transduction histidine kinase Cthe_2814 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 125973213 Common - putative agmatinase Cthe_0695 159 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 125975209 Common rpsL 30S ribosomal protein S12 Cthe_2727 225 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 125973889 Common - copper amine oxidase-like protein Cthe_1374 10 None None None 125973042 Common - hypothetical protein Cthe_0522 5 None None None 125974021 Common - short-chain dehydrogenase/reductase SDR Cthe_1510 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 125975171 Common - transcriptional regulator, GntR family Cthe_2689 219 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 125975157 Nonpathogen - hypothetical protein Cthe_2675 1 None None None 125972951 Common - hydrogenase, Fe-only Cthe_0430 184 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 125973723 Common - GCN5-related N-acetyltransferase Cthe_1208 35 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 125975482 Common - hydrogenase, Fe-only Cthe_3003 104 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 125973629 Common - Tn7-like transposition protein D Cthe_1114 19 None None None 125974393 Common - transposase, mutator type Cthe_1889 88 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973596 Common - hypothetical protein Cthe_1081 2 None None None 125973283 Common - ribosomal protein L19 Cthe_0765 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 125975187 Common - Transketolase, central region Cthe_2705 231 COG3958 COG3958, Transketolase, C-terminal subunit Carbohydrate transport and metabolism 125972919 Common - protein of unknown function DUF74 Cthe_0398 102 COG0393 COG0393, Uncharacterized conserved protein Function unknown 125975690 Common - protein of unknown function DUF324 Cthe_3212 10 COG1604 COG1604, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 125973710 Common - hypothetical protein Cthe_1195 3 None None None 125972835 Common - glycosyltransferase 28-like protein Cthe_0314 13 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 125974390 Common - Integrase, catalytic region Cthe_1886 155 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974272 Common - NifU-related domain containing protein Cthe_1768 6 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 125975403 Common - ribosomal protein L15 Cthe_2922 218 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 125975033 Nonpathogen - cellulosome enzyme, dockerin type I Cthe_2549 1 None None None 125973020 Nonpathogen - hypothetical protein Cthe_0500 2 None None None 125972670 Common - ribonuclease R Cthe_0146 200 COG0557 VacB, Exoribonuclease R Transcription 125974566 Common - periplasmic sensor signal transduction histidine kinase Cthe_2076 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 125975052 Nonpathogen - hypothetical protein Cthe_2568 2 None None None 125972974 Common - hypothetical protein Cthe_0453 2 None None None 125974482 Nonpathogen - hypothetical protein Cthe_1981 1 None None None 125975330 Common - phage major capsid protein, HK97 Cthe_2848 14 COG4653 COG4653, Predicted phage phi-C31 gp36 major capsid-like protein General function prediction only 125974397 Common - hypothetical protein Cthe_1894 5 None None None 125974983 Common - N-acetylmuramoyl-L-alanine amidase Cthe_2498 13 COG5632 COG5632, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 125972622 Common - peptidase M50 Cthe_0098 55 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 125974570 Common - NUDIX hydrolase Cthe_2080 11 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 125973197 Common - Serine-type D-Ala-D-Ala carboxypeptidase Cthe_0679 157 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 125975561 Nonpathogen - hypothetical protein Cthe_3082 1 None None None 125972905 Common - ABC transporter related protein Cthe_0384 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 125972810 Common - MCP methyltransferase, CheR-type Cthe_0288 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 125974188 Common - Integrase, catalytic region Cthe_1683 153 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974771 Common - phage integrase Cthe_2286 33 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 125974238 Common - phage / plasmid primase, P4 family Cthe_1734 46 COG3378 COG3378, Predicted ATPase General function prediction only 125975087 Common - ATP synthase F0, B subunit Cthe_2604 6 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 125974524 Common - conserved hypothetical protein precursor Cthe_2030 17 COG5185 HEC1, Protein involved in chromosome segregation, interacts with SMC proteins Cell division and chromosome partitioning 125974762 Nonpathogen - hypothetical protein Cthe_2277 2 None None None 125972683 Common - Integrase, catalytic region Cthe_0159 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 125972891 Common - conserved hypothetical radical SAM protein Cthe_0370 68 COG1242 COG1242, Predicted Fe-S oxidoreductase General function prediction only 125973013 Common - CheC, inhibitor of MCP methylation Cthe_0492 48 COG1776 CheC, Chemotaxis protein CheC, inhibitor of MCP methylation Cell motility and secretion / Signal transduction mechanisms 125972776 Common - protein of unknown function DUF58 Cthe_0254 25 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 125975635 Common - pyruvate carboxyltransferase Cthe_3157 204 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 125973365 Common - translation elongation factor P Cthe_0847 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 125972729 Common - hypothetical protein Cthe_0205 11 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 125974984 Nonpathogen - hypothetical protein Cthe_2499 3 None None None 125972748 Nonpathogen - hypothetical protein Cthe_0226 1 None None None 125973413 Common dnaG DNA primase Cthe_0896 216 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 125975059 Nonpathogen - hypothetical protein Cthe_2576 1 None None None 125975654 Common - small acid-soluble spore protein, alpha/beta type Cthe_3176 6 None None None 125974469 Common - cell divisionFtsK/SpoIIIE Cthe_1968 189 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 125974538 Nonpathogen - hypothetical protein Cthe_2048 1 None None None 125974375 Common - Tn7-like transposition protein D Cthe_1871 18 None None None 125974445 Common - protein of unknown function DUF458 Cthe_1944 13 COG1978 COG1978, Uncharacterized protein conserved in bacteria Function unknown 125975155 Nonpathogen - hypothetical protein Cthe_2673 1 None None None 125975418 Common - cobalt transport protein Cthe_2937 79 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 125972606 Common - ATP-dependent protease La Cthe_0082 214 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 125973049 Nonpathogen - hypothetical protein Cthe_0530 1 None None None 125975368 Common - phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase Cthe_2887 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 125973486 Common - transposase, mutator type Cthe_0970 89 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 125972564 Common - Cellulase., Cellulose 1,4-beta-cellobiosidase Cthe_0040 20 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 125974453 Nonpathogen - hypothetical protein Cthe_1952 1 None None None 125974326 Common - inner-membrane translocator Cthe_1822 148 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 125975263 Nonpathogen - hypothetical protein Cthe_2781 1 None None None 125972596 Common - phage shock protein C, PspC Cthe_0072 38 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 125975043 Common - DegT/DnrJ/EryC1/StrS aminotransferase Cthe_2559 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 125972880 Nonpathogen - hypothetical protein Cthe_0359 3 None None None 125973076 Common - polysaccharide deacetylase Cthe_0557 135 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 125973741 Common - dihydrofolate reductase region Cthe_1226 147 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 125973393 Common - glycosyl transferase, family 39 Cthe_0876 15 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 125975001 Common - acetolactate synthase, large subunit, biosynthetic type Cthe_2516 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 125973298 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Cthe_0780 198 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 125973946 Common - transposase IS200-like protein Cthe_1432 72 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973340 Common - IstB-like ATP-binding protein Cthe_0822 96 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 125972722 Common - Glutamate synthase (NADPH) Cthe_0198 205 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 125974924 Common - GCN5-related N-acetyltransferase Cthe_2439 8 COG0456 RimI, Acetyltransferases General function prediction only 125974560 Common - hypothetical protein Cthe_2070 11 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 125973848 Nonpathogen - hypothetical protein Cthe_1333 1 None None None 125975632 Common - hypothetical protein Cthe_3154 15 COG4720 COG4720, Predicted membrane protein Function unknown 125974132 Common - phage protein, HK97 gp10 family Cthe_1625 5 None None None 125973931 Nonpathogen - hypothetical protein Cthe_1417 1 None None None 125974033 Common - NADPH-dependent FMN reductase Cthe_1522 34 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 125975575 Common - glycosyl transferase, family 2 Cthe_3097 171 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 125975085 Common - F0F1 ATP synthase subunit A Cthe_2602 202 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 125975313 Common - transposase Cthe_2831 84 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973582 Common - GTP-binding protein Era Cthe_1067 231 COG1159 Era, GTPase General function prediction only 125973533 Common - binding-protein-dependent transport systems inner membrane component Cthe_1018 192 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 125974097 Common - extracellular solute-binding protein, family 1 Cthe_1588 143 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 125973610 Common - cell divisionFtsK/SpoIIIE Cthe_1095 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 125975414 Common - ribosomal protein L17 Cthe_2933 190 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 125973737 Common - RNA methyltransferase, TrmH family, group 3 Cthe_1222 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 125973285 Common - 16S rRNA processing protein RimM Cthe_0767 182 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 125973300 Common - putative methyl-accepting chemotaxis sensory transducer Cthe_0782 3 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 125973694 Nonpathogen - hypothetical protein Cthe_1179 2 None None None 125974319 Common ureE urease accessory protein UreE Cthe_1815 25 COG2371 UreE, Urease accessory protein UreE Posttranslational modification, protein turnover, chaperones 125972713 Common - non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family Cthe_0189 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 125974467 Nonpathogen - hypothetical protein Cthe_1966 1 None None None 125975224 Common - Endopeptidase La Cthe_2742 243 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 125975657 Common - Serine-type D-Ala-D-Ala carboxypeptidase Cthe_3179 157 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 125975096 Common - S-layer-like domain containing protein Cthe_2613 21 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 125975689 Common - protein of unknown function DUF324 Cthe_3211 8 None None None 125973647 Common - hypothetical protein Cthe_1132 3 COG4848 COG4848, Uncharacterized protein conserved in bacteria Function unknown 125974546 Nonpathogen - hypothetical protein Cthe_2056 2 None None None 125972933 Common - glycoside hydrolase, family 9 Cthe_0412 18 None None None 125972755 Common - GCN5-related N-acetyltransferase Cthe_0233 168 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 125973791 Common - pantetheine-phosphate adenylyltransferase Cthe_1276 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 125973081 Common - protein of unknown function DUF1312 Cthe_0562 14 COG5341 COG5341, Uncharacterized protein conserved in bacteria Function unknown 125974301 Common - 3-phosphoshikimate 1-carboxyvinyltransferase Cthe_1797 237 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 125973911 Common - glycosyl transferase, family 8 Cthe_1397 31 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 125974629 Common - recombination protein RecR Cthe_2142 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 125975257 Common - transcriptional regulator, Crp/Fnr family Cthe_2775 174 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 125973091 Common - radical SAM enzyme, Cfr family Cthe_0572 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 125975102 Common - cell shape determining protein, MreB/Mrl family Cthe_2619 216 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 125973652 Nonpathogen - hypothetical protein Cthe_1137 1 None None None 125975451 Common - hypothetical protein Cthe_2971 5 None None None 125974894 Nonpathogen - hypothetical protein Cthe_2409 1 None None None 125972769 Common - DNA mismatch repair protein MutS-like protein Cthe_0247 197 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 125973642 Common - phage integrase Cthe_1127 212 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 125974868 Nonpathogen - hypothetical protein Cthe_2383 4 None None None 125974978 Common - phage-like element PBSX protein Cthe_2493 4 None None None 125973157 Common - glycoside hydrolase, family 13-like protein Cthe_0639 5 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 125974471 Nonpathogen - hypothetical protein Cthe_1970 1 None None None 125973412 Common - RNA polymerase sigma factor RpoD Cthe_0895 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 125973121 Common - GCN5-related N-acetyltransferase Cthe_0603 10 COG0456 RimI, Acetyltransferases General function prediction only 125975191 Nonpathogen - hypothetical protein Cthe_2709 7 None None None 125972786 Common - hypothetical protein Cthe_0264 2 None None None 125972993 Common - flagellar hook capping protein Cthe_0472 96 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 125975601 Common - von Willebrand factor, type A Cthe_3123 18 None None None 125974766 Common - response regulator receiver modulated CheB methylesterase Cthe_2281 218 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 125975078 Common - Sua5/YciO/YrdC/YwlC family protein Cthe_2595 242 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 125973400 Common - flagellar protein Cthe_0883 9 None None None 125973980 Nonpathogen - hypothetical protein Cthe_1468 1 None None None 125973236 Nonpathogen - hypothetical protein Cthe_0718 2 None None None 125973378 Common - cell envelope-related transcriptional attenuator Cthe_0861 55 COG1316 LytR, Transcriptional regulator Transcription 125972572 Common - copper amine oxidase-like protein Cthe_0048 10 None None None 125975077 Common - zinc/iron permease Cthe_2594 110 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 125975464 Nonpathogen - hypothetical protein Cthe_2985 2 None None None 125972537 Nonpathogen - YD repeat protein Cthe_0012 1 None None None 125973520 Common tsf elongation factor Ts Cthe_1005 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 125974813 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Cthe_2328 212 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 125975126 Common - DegT/DnrJ/EryC1/StrS aminotransferase Cthe_2644 191 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 125975697 Nonpathogen - CRISPR-associated protein Cas2 Cthe_3219 10 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 125973601 Common - dTDP-glucose 4,6-dehydratase Cthe_1086 229 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 125975109 Common - purine operon repressor Cthe_2627 44 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 125975025 Common - Mov34/MPN/PAD-1 Cthe_2540 48 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 125974006 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Cthe_1495 13 COG5015 COG5015, Uncharacterized conserved protein Function unknown 125972825 Common - Integrase, catalytic region Cthe_0304 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 125973345 Common - hemolysin A Cthe_0827 133 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 125974451 Nonpathogen - hypothetical protein Cthe_1950 1 None None None 125974508 Common - Integrase, catalytic region Cthe_2012 153 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973678 Common - phosphoglucosamine mutase Cthe_1163 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 125974809 Common - Resolvase-like protein Cthe_2324 84 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 125974478 Nonpathogen - hypothetical protein Cthe_1977 1 None None None 125972735 Common - glycoside hydrolase, family 16 Cthe_0211 28 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 125973813 Common - ribosomal protein L25 Cthe_1298 79 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 125973323 Common - response regulator receiver protein Cthe_0805 202 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 125975180 Common - putative transcriptional regulator, CopG family Cthe_2698 13 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 125973010 Common - response regulator receiver modulated CheB methylesterase Cthe_0489 221 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 125974844 Common - metal dependent phosphohydrolase Cthe_2359 36 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 125974401 Nonpathogen - hypothetical protein Cthe_1898 1 None None None 125973999 Common - hypothetical protein Cthe_1487 4 COG5658 COG5658, Predicted integral membrane protein Function unknown 125972579 Nonpathogen - hypothetical protein Cthe_0055 1 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 125974058 Common - Enoyl-CoA hydratase/isomerase Cthe_1548 175 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 125974139 Common - hypothetical protein Cthe_1633 5 None None None 125973039 Common - DNA methylase N-4/N-6 Cthe_0519 94 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 125974911 Common - OmpA/MotB Cthe_2426 152 COG1360 MotB, Flagellar motor protein Cell motility and secretion 125975321 Common - hypothetical protein Cthe_2839 6 None None None 125974613 Common - hypothetical protein Cthe_2123 4 None None None 125973241 Common - tyrosyl-tRNA synthetase Cthe_0723 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 125973961 Common - MATE efflux family protein Cthe_1448 154 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 125973874 Common - glycosyltransferase 28-like protein Cthe_1359 15 COG5017 COG5017, Uncharacterized conserved protein Function unknown 125973884 Common - histidine triad (HIT) protein Cthe_1369 229 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 125973078 Common - single-strand DNA-binding protein Cthe_0559 12 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 125974737 Common - thioesterase family protein Cthe_2252 35 COG5496 COG5496, Predicted thioesterase General function prediction only 125973853 Common - Flp pilus assembly protein TadB-like protein Cthe_1338 36 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 125975044 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Cthe_2560 167 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 125974914 Common - protein of unknown function UPF0118 Cthe_2429 72 COG0628 PerM, Predicted permease General function prediction only 125973063 Common - protein serine/threonine phosphatases Cthe_0544 128 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 125974971 Common - hypothetical protein Cthe_2486 5 None None None 125972632 Nonpathogen - type IV pilus assembly PilZ Cthe_0108 1 None None None 125973977 Common - Redoxin Cthe_1465 217 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 125975715 Common - Relaxase/mobilization nuclease domain containing protein Cthe_3237 9 None None None 125974998 Common - peptidase S1 and S6, chymotrypsin/Hap Cthe_2513 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 125974412 Nonpathogen - hypothetical protein Cthe_1910 1 None None None 125973512 Common - 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase Cthe_0997 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 125974104 Common - hypothetical protein Cthe_1595 3 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 125975518 Common - cell divisionFtsK/SpoIIIE Cthe_3039 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 125974382 Common - hypothetical protein Cthe_1878 3 None None None 125975508 Common - CheW protein Cthe_3029 132 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 125973106 Common - transposase, mutator type Cthe_0587 88 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973562 Nonpathogen - hypothetical protein Cthe_1047 1 None None None 125975236 Common - beta-lactamase-like protein Cthe_2754 44 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 125975543 Common - polysaccharide biosynthesis protein Cthe_3064 60 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 125975475 Common - intracellular protease, PfpI family Cthe_2996 144 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 125974231 Common - hypothetical protein Cthe_1727 12 None None None 125973175 Nonpathogen - hypothetical protein Cthe_0657 1 None None None 125973089 Common - peptidase, membrane zinc metallopeptidase, putative Cthe_0570 42 COG2738 COG2738, Predicted Zn-dependent protease General function prediction only 125973599 Common - spore coat protein Cthe_1084 6 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 125974295 Common - UvrB/UvrC protein Cthe_1791 20 COG3880 COG3880, Uncharacterized protein with conserved CXXC pairs Function unknown 125975593 Common - hypothetical protein Cthe_3115 21 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 125973825 Common - Accessory gene regulator B Cthe_1310 10 COG4512 AgrB, Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Transcription 125974307 Common - cobalamin (vitamin B12) biosynthesis CbiM protein Cthe_1803 60 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 125972986 Common - flagellar M-ring protein FliF Cthe_0465 113 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 125975563 Common - putative RNA methylase Cthe_3084 133 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 125972963 Common - Polypeptide-transport-associated, FtsQ-type Cthe_0442 8 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 125974773 Common - PEBP Cthe_2288 13 COG1881 COG1881, Phospholipid-binding protein General function prediction only 125974920 Common - electron transport complex, RnfABCDGE type, B subunit Cthe_2435 120 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 125972944 Common - iron-containing alcohol dehydrogenase Cthe_0423 221 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 125972795 Common - metal dependent phosphohydrolase Cthe_0273 178 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 125975294 Common - glycoside hydrolase, family 9 Cthe_2812 19 None None None 125973181 Common - hypothetical protein Cthe_0663 4 None None None 125973553 Common - germination protease Cthe_1038 15 None None None 125973689 Common - protein of unknown function DUF155 Cthe_1174 18 COG1723 COG1723, Uncharacterized conserved protein Function unknown 125973895 Common - response regulator receiver protein Cthe_1380 223 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 125974187 Common - transposase IS3/IS911 Cthe_1682 39 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973609 Common - hypothetical protein Cthe_1094 73 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 125972664 Common - phosphoglyceromutase Cthe_0140 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 125973303 Nonpathogen - hypothetical protein Cthe_0785 1 None None None 125975282 Common - aminotransferase, class I and II Cthe_2800 232 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 125974142 Common - hypothetical protein Cthe_1636 8 None None None 125972682 Common - ribonuclease, Rne/Rng family Cthe_0158 186 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 125973862 Common - GatB/YqeY Cthe_1347 155 COG1610 COG1610, Uncharacterized conserved protein Function unknown 125972703 Common - argininosuccinate synthase Cthe_0179 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 125973955 Common - ATP-dependent transcriptional regulator-like protein Cthe_1442 41 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 125973833 Common - response regulator receiver protein Cthe_1318 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 125975386 Common - Ribosomal protein L25/L23 Cthe_2905 214 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 125974601 Common - protein of unknown function DUF214 Cthe_2111 16 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 125973052 Common - Radical SAM Cthe_0533 149 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 125974648 Common - anti-sigma-factor antagonist Cthe_2163 59 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 125972726 Common - glutamine synthetase, type I Cthe_0202 225 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 125974420 Common - Orn/Lys/Arg decarboxylase, major region Cthe_1918 109 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 125973434 Common - glutaminyl-tRNA synthetase Cthe_0917 248 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 125975644 Common - glucose-1-phosphate adenylyltransferase Cthe_3166 198 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 125975173 Common - galactoside O-acetyltransferase Cthe_2691 202 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 125972819 Common - methyl-accepting chemotaxis sensory transducer Cthe_0298 157 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 125973538 Common - protein of unknown function DUF205 Cthe_1023 169 COG0344 COG0344, Predicted membrane protein Function unknown 125973983 Common - glycoside hydrolase, family 5 Cthe_1471 10 COG2730 BglC, Endoglucanase Carbohydrate transport and metabolism 125972624 Nonpathogen - hypothetical protein Cthe_0100 1 None None None 125975618 Common - transcriptional regulator, TetR family Cthe_3140 37 COG1309 AcrR, Transcriptional regulator Transcription 125974786 Common - CRISPR-associated autoregulator, DevR family Cthe_2301 22 COG1857 COG1857, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 125975279 Common - thiamine pyrophosphate enzyme-like TPP-binding Cthe_2797 88 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 125974060 Common - transposase IS116/IS110/IS902 Cthe_1550 95 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 125972848 Common - S-layer-like domain containing protein Cthe_0327 29 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 125975672 Nonpathogen - hypothetical protein Cthe_3194 3 None None None 125972676 Common - aldo/keto reductase Cthe_0152 188 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 125972831 Common - hypothetical protein Cthe_0310 26 COG3584 COG3584, Uncharacterized protein conserved in bacteria Function unknown 125974166 Common - transposase, IS4 Cthe_1660 28 None None None 125973282 Common - signal peptidase I Cthe_0764 188 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 125974935 Nonpathogen - hypothetical protein Cthe_2450 1 None None None 125974128 Common - hypothetical protein Cthe_1621 4 None None None 125975068 Common - biotin--acetyl-CoA-carboxylase ligase Cthe_2585 223 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 125975444 Common - binding-protein-dependent transport systems inner membrane component Cthe_2964 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 125973634 Common - hypothetical protein Cthe_1119 3 None None None 125975202 Common - ribosomal protein L11 Cthe_2720 247 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 125975350 Nonpathogen - hypothetical protein Cthe_2869 1 None None None 125973840 Common - putative oxygen-independent coproporphyrinogen III oxidase Cthe_1325 207 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 125974408 Common - glycosyl transferase, family 28 Cthe_1906 51 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 125975465 Common - hypothetical protein Cthe_2986 2 None None None 125974657 Common - ribosomal protein L31 Cthe_2172 200 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 125974433 Common - S-layer-like domain containing protein Cthe_1932 9 None None None 125973547 Common - glutamyl-tRNA(Gln) amidotransferase, A subunit Cthe_1032 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 125972821 Common - Allergen V5/Tpx-1 related Cthe_0300 91 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 125973059 Common - protein of unknown function DUF214 Cthe_0540 65 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 125974419 Common - ATPase, P-type (transporting), HAD superfamily, subfamily IC Cthe_1917 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 125975281 Common - Cystathionine gamma-synthase Cthe_2799 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 125975017 Common - sulfate ABC transporter, inner membrane subunit CysT Cthe_2532 237 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 125972549 Common - biotin biosynthesis protein BioC Cthe_0024 158 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 125974385 Common - Integrase, catalytic region Cthe_1881 153 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 125972987 Common fliG flagellar motor switch protein G Cthe_0466 125 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 125974488 Nonpathogen - hypothetical protein Cthe_1987 1 None None None 125973033 Common - DNA binding domain, excisionase family Cthe_0513 2 None None None 125973137 Common - FeoA Cthe_0619 58 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 125973558 Nonpathogen - hypothetical protein Cthe_1043 1 None None None 125975065 Common - dihydroneopterin aldolase Cthe_2582 84 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 125975355 Common - phosphoenolpyruvate carboxykinase Cthe_2874 59 COG1274 PckA, Phosphoenolpyruvate carboxykinase (GTP) Energy production and conversion 125974481 Common - hypothetical protein Cthe_1980 17 None None None 125973388 Common - Phosphoribosylanthranilate isomerase Cthe_0871 197 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 125973505 Common - ribosome-binding factor A Cthe_0990 188 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 125973162 Common - Vitamin B12 dependent methionine synthase, activation region Cthe_0644 9 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 125974740 Common - tRNA(Ile)-lysidine synthetase Cthe_2255 237 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 125973992 Common - hypothetical protein Cthe_1480 99 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 125974075 Common - Nitrogenase Cthe_1566 57 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 125974192 Common - Integrase, catalytic region Cthe_1687 153 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973771 Common - glycoside hydrolase, family 3-like protein Cthe_1256 103 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 125973758 Common - GCN5-related N-acetyltransferase Cthe_1243 21 COG0456 RimI, Acetyltransferases General function prediction only 125975138 Common - MazG family protein Cthe_2656 156 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 125972830 Common - excinuclease ABC subunit B Cthe_0309 232 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 125974073 Common - GCN5-related N-acetyltransferase Cthe_1564 69 COG0456 RimI, Acetyltransferases General function prediction only 125973222 Nonpathogen - hypothetical protein Cthe_0704 5 None None None 125972559 Common - 4Fe-4S ferredoxin, iron-sulfur binding Cthe_0035 45 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 125975112 Common - ribose-phosphate pyrophosphokinase Cthe_2630 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 125975526 Common - Peptidoglycan glycosyltransferase Cthe_3047 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 125975589 Common - hypothetical protein Cthe_3111 4 None None None 125973124 Common - DNA internalization-related competence protein ComEC/Rec2 Cthe_0606 187 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 125973023 Common - 2'-5' RNA ligase Cthe_0503 107 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 125974605 Common - protein of unknown function DUF77 Cthe_2115 28 COG0011 COG0011, Uncharacterized conserved protein Function unknown 125974900 Common - cell wall hydrolase, SleB Cthe_2415 46 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 125974572 Nonpathogen - hypothetical protein Cthe_2082 3 None None None 125973657 Nonpathogen - hypothetical protein Cthe_1142 1 None None None 125975425 Common - periplasmic sensor signal transduction histidine kinase Cthe_2944 52 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 125973117 Common - thiazole biosynthesis protein ThiH Cthe_0599 56 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 125974667 Common - Ig-like, group 2 Cthe_2182 31 COG4632 EpsL, Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Carbohydrate transport and metabolism 125975524 Common - FHA domain containing protein Cthe_3045 64 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 125974361 Common - carboxyl-terminal protease Cthe_1857 185 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 125972818 Nonpathogen - hypothetical protein Cthe_0297 1 None None None 125973636 Nonpathogen - hypothetical protein Cthe_1121 1 None None None 125972709 Common - cell wall hydrolase/autolysin Cthe_0185 184 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 125973276 Common - protein of unknown function UPF0102 Cthe_0758 118 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 125972653 Common - metal dependent phosphohydrolase Cthe_0129 179 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 125974972 Common - hypothetical protein Cthe_2487 5 None None None 125972917 Common - ABC transporter related protein Cthe_0396 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 125974443 Common - hypothetical protein Cthe_1942 18 COG5401 COG5401, Spore germination protein General function prediction only 125972774 Nonpathogen - hypothetical protein Cthe_0252 1 None None None 125974562 Common - hypothetical protein Cthe_2072 3 None None None 125974579 Common - glycoside hydrolase, family 48 Cthe_2089 9 None None None 125974702 Common - flagellar protein FliS Cthe_2217 49 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 125975595 Common - zinc/iron permease Cthe_3117 118 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 125974496 Common - IstB-like ATP-binding protein Cthe_1996 96 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 125973458 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Cthe_0941 204 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 125974504 Common - IstB-like ATP-binding protein Cthe_2005 98 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 125973096 Common - thiamine pyrophosphokinase Cthe_0577 56 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 125974281 Common - amidohydrolase Cthe_1777 78 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 125974728 Common - flagellar hook-associated protein FlgK Cthe_2243 124 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 125974707 Common - glycosyltransferase 28-like protein Cthe_2222 37 COG3980 spsG, Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase Cell envelope biogenesis, outer membrane 125974194 Nonpathogen - hypothetical protein Cthe_1689 1 None None None 125974996 Common - MscS Mechanosensitive ion channel Cthe_2511 154 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 125973445 Common pdxA 4-hydroxythreonine-4-phosphate dehydrogenase Cthe_0928 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 125973666 Common - hypothetical protein Cthe_1151 3 None None None 125975277 Common - pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit Cthe_2795 69 COG1144 COG1144, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit Energy production and conversion 125974510 Nonpathogen - hypothetical protein Cthe_2014 1 None None None 125975149 Common - transcriptional regulator, TetR family Cthe_2667 19 COG1309 AcrR, Transcriptional regulator Transcription 125975326 Common - conserved hypothetical protein precursor Cthe_2844 19 COG1372 COG1372, Intein/homing endonuclease DNA replication, recombination, and repair 125972946 Common - hypothetical protein Cthe_0425 8 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 125975307 Common - conserved hypothetical protein precursor Cthe_2825 20 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 125973132 Common - indolepyruvate oxidoreductase subunit B Cthe_0614 81 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 125973142 Common - glycoside hydrolase, family 9-like Ig-like Cthe_0624 44 COG3291 COG3291, FOG: PKD repeat General function prediction only 125974686 Common - transposase, mutator type Cthe_2201 88 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973603 Common - hypothetical protein Cthe_1088 4 None None None 125974298 Common - elongation factor G Cthe_1794 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 125974038 Common - periplasmic sensor signal transduction histidine kinase Cthe_1527 207 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 125974043 Common - transposase, mutator type Cthe_1533 89 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973334 Common - NAD(+) kinase Cthe_0816 240 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 125974926 Common - transcriptional regulator, DeoR family Cthe_2441 114 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 125972882 Nonpathogen - hypothetical protein Cthe_0361 3 None None None 125973260 Nonpathogen - hypothetical protein Cthe_0742 1 None None None 125972617 Common - septum site-determining protein MinD Cthe_0093 169 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 125972781 Common - Rhomboid-like protein Cthe_0259 11 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 125974674 Common - diguanylate cyclase with GAF sensor Cthe_2189 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 125973802 Common - periplasmic sensor signal transduction histidine kinase Cthe_1287 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 125973876 Common - NAD-dependent epimerase/dehydratase Cthe_1361 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 125975489 Nonpathogen - hypothetical protein Cthe_3010 3 None None None 125972553 Common - hypothetical protein Cthe_0029 24 COG4832 COG4832, Uncharacterized conserved protein Function unknown 125974350 Common - periplasmic sensor signal transduction histidine kinase Cthe_1846 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 125974338 Nonpathogen - hypothetical protein Cthe_1834 1 None None None 125974345 Common - hypothetical protein Cthe_1841 86 COG1606 COG1606, ATP-utilizing enzymes of the PP-loop superfamily General function prediction only 125974908 Nonpathogen - hypothetical protein Cthe_2423 1 None None None 125972543 Nonpathogen - hypothetical protein Cthe_0018 2 None None None 125974581 Common - hypothetical protein Cthe_2091 3 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 125975213 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Cthe_2731 172 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 125973468 Common - orotidine 5'-phosphate decarboxylase Cthe_0951 68 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 125975488 Nonpathogen - hypothetical protein Cthe_3009 1 None None None 125972574 Nonpathogen - hypothetical protein Cthe_0050 2 None None None 125974883 Common - putative spore coat protein Cthe_2398 6 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 125975660 Common - Integrase, catalytic region Cthe_3182 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 125973176 Common - hypothetical protein Cthe_0658 7 None None None 125975534 Nonpathogen - hypothetical protein Cthe_3055 2 None None None 125974246 Common - Helix-turn-helix, type 11 containing protein Cthe_1742 6 COG2378 COG2378, Predicted transcriptional regulator Transcription 125974012 Common - ABC transporter, transmembrane region Cthe_1501 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 125975553 Common - Cof-like hydrolase Cthe_3074 128 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 125972743 Common - 5-nitroimidazole antibiotic resistance protein Cthe_0219 33 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 125975493 Common - hydrogenase formation HypD protein Cthe_3014 108 COG0409 HypD, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 125973594 Common - Nucleotidyl transferase Cthe_1079 240 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 125973671 Common - zinc finger, CHC2-type Cthe_1156 7 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 125973110 Common - Methyltransferase type 11 Cthe_0592 100 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 125975625 Common - ABC transporter related protein Cthe_3147 248 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 125974630 Common - hypothetical protein Cthe_2143 153 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 125975373 Common - chaperonin GroEL Cthe_2892 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 125974115 Common - Recombinase Cthe_1608 10 None None None 125974929 Common - Transketolase-like protein Cthe_2444 226 COG3958 COG3958, Transketolase, C-terminal subunit Carbohydrate transport and metabolism 125973794 Common - ribosomal protein L28 Cthe_1279 54 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 125974638 Nonpathogen - hypothetical protein Cthe_2152 3 COG2246 COG2246, Predicted membrane protein Function unknown 125973419 Common - 3-methyl-2-oxobutanoate hydroxymethyltransferase Cthe_0902 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 125974340 Common - hypothetical protein Cthe_1836 5 None None None 125974691 Nonpathogen - hypothetical protein Cthe_2206 1 None None None 125973357 Common - stage III sporulation protein AG Cthe_0839 15 None None None 125973463 Common - Phosphoglycerate mutase Cthe_0946 179 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 125974328 Common - two component transcriptional regulator, AraC family Cthe_1824 225 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 125972608 Nonpathogen - hypothetical protein Cthe_0084 2 None None None 125975117 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Cthe_2635 9 COG5015 COG5015, Uncharacterized conserved protein Function unknown 125974373 Common - ornithine carbamoyltransferase Cthe_1869 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 125972809 Common - multi-sensor hybrid histidine kinase Cthe_0287 226 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 125975480 Common - protein of unknown function DUF47 Cthe_3001 66 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 125973199 Common - inositol-5-monophosphate dehydrogenase Cthe_0681 233 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 125972727 Common - response regulator receiver and ANTAR domain protein Cthe_0203 38 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 125973828 Common - phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase Cthe_1313 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 125972907 Nonpathogen - hypothetical protein Cthe_0386 1 None None None 125975200 Common - preprotein translocase, SecE subunit Cthe_2718 18 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 125972720 Common - glutamine synthetase, catalytic region Cthe_0196 126 COG3968 COG3968, Uncharacterized protein related to glutamine synthetase General function prediction only 125975153 Common - transposase, mutator type Cthe_2671 89 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973774 Common - CDP-alcohol phosphatidyltransferase Cthe_1259 200 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 125973339 Common - coagulation factor 5/8 type-like protein Cthe_0821 19 None None None 125973680 Common - YbbR-like protein Cthe_1165 26 COG4856 COG4856, Uncharacterized protein conserved in bacteria Function unknown 125975615 Nonpathogen - hypothetical protein Cthe_3137 1 None None None 125974258 Common - periplasmic binding protein Cthe_1754 182 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 125974531 Common - UvrD/REP helicase Cthe_2039 228 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 125974173 Common - ABC-2 type transporter Cthe_1667 97 COG1511 COG1511, Predicted membrane protein Function unknown 125975124 Common - transferase hexapeptide repeat Cthe_2642 187 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 125974251 Common - DNA mismatch endonuclease vsr Cthe_1747 69 COG3727 Vsr, DNA G:T-mismatch repair endonuclease DNA replication, recombination, and repair 125975412 Common - ribosomal protein S4 Cthe_2931 247 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 125974089 Common - inner-membrane translocator Cthe_1580 110 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 125972762 Common - hypothetical protein Cthe_0240 11 COG5036 COG5036, SPX domain-containing protein involved in vacuolar polyphosphate accumulation Inorganic ion transport and metabolism 125973216 Common - Integrase, catalytic region Cthe_0698 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 125973248 Common - hypothetical protein Cthe_0730 16 None None None 125974357 Common - cold-shock DNA-binding domain protein Cthe_1853 166 COG1278 CspC, Cold shock proteins Transcription 125975656 Common - protein of unknown function DUF342 Cthe_3178 37 COG1315 COG1315, Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain DNA replication, recombination, and repair 125972583 Common - type 3a, cellulose-binding Cthe_0059 18 None None None 125973484 Common - transposase, IS4 Cthe_0967 28 None None None 125973715 Common - adenosylhomocysteinase Cthe_1200 178 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 125973717 Common - major facilitator superfamily MFS_1 Cthe_1202 108 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 125973403 Common - DNA polymerase I Cthe_0886 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 125973743 Common thrS threonyl-tRNA synthetase Cthe_1228 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 125973479 Common - dihydrodipicolinate synthase Cthe_0962 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 125975337 Common - hypothetical protein Cthe_2855 6 None None None 125975667 Nonpathogen - hypothetical protein Cthe_3189 1 None None None 125974956 Common - hypothetical protein Cthe_2471 8 None None None 125974212 Common - phage putative tail component Cthe_1708 8 COG4722 COG4722, Phage-related protein Function unknown 125972868 Common - 6-phosphofructokinase Cthe_0347 156 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 125972594 Common asnC asparaginyl-tRNA synthetase Cthe_0070 222 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 125972912 Common - ABC transporter related protein Cthe_0391 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 125973470 Common pyrB aspartate carbamoyltransferase catalytic subunit Cthe_0953 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 125974143 Common - virulence-related protein Cthe_1637 13 None None None 125974527 Nonpathogen - hypothetical protein Cthe_2033 1 None None None 125973747 Common - AMP-dependent synthetase and ligase Cthe_1232 217 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 125972694 Nonpathogen - hypothetical protein Cthe_0170 3 None None None 125975056 Common - ABC transporter related protein Cthe_2573 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 125972562 Common - chemotaxis protein cheW Cthe_0038 77 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 125973268 Common - spermidine/putrescine ABC transporter ATPase subunit Cthe_0750 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 125973211 Common - Pseudouridine synthase, Rsu Cthe_0693 205 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 125973296 Nonpathogen - hypothetical protein Cthe_0778 3 COG3679 COG3679, Uncharacterized conserved protein Function unknown 125974477 Common - Integrase, catalytic region Cthe_1976 153 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 125975692 Common - hypothetical protein Cthe_3214 10 None None None 125973087 Common - methionyl-tRNA formyltransferase Cthe_0568 222 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 125975189 Common - ABC-type transport system involved in multi-copper enzyme maturation, permease component Cthe_2707 65 None None None 125973627 Common - transcriptional regulator, ArsR family Cthe_1112 160 COG0640 ArsR, Predicted transcriptional regulators Transcription 125975708 Nonpathogen - hypothetical protein Cthe_3230 1 None None None 125974399 Common - metallophosphoesterase Cthe_1896 96 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 125973787 Common - putative RNA polymerase sigma factor SigI Cthe_1272 16 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 125974576 Common - peptidase U32 Cthe_2086 140 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 125974796 Common - hypothetical protein Cthe_2311 4 None None None 125974981 Common - hypothetical protein Cthe_2496 2 None None None 125975608 Nonpathogen - hypothetical protein Cthe_3130 2 None None None 125973044 Nonpathogen - hypothetical protein Cthe_0524 1 None None None 125973347 Common - hypothetical protein Cthe_0829 12 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 125974753 Common - V-type ATP synthase subunit B Cthe_2268 247 COG1156 NtpB, Archaeal/vacuolar-type H+-ATPase subunit B Energy production and conversion 125972885 Common - transcriptional regulator, XRE family Cthe_0364 26 COG1476 COG1476, Predicted transcriptional regulators Transcription 125973560 Nonpathogen - hypothetical protein Cthe_1045 1 None None None 125974019 Common - hypothetical protein Cthe_1508 39 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 125973579 Common - aminotransferase, class V Cthe_1064 239 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 125975669 Common - ATPase involved in chromosome partitioning-like protein Cthe_3191 13 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 125974270 Common - gamma-glutamyl kinase Cthe_1766 191 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 125975401 Common - ribosomal protein S5-like protein Cthe_2920 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 125974460 Common - Methyltransferase type 11 Cthe_1959 60 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 125975050 Common - Radical SAM Cthe_2566 94 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 125973326 Common - MCP methyltransferase, CheR-type Cthe_0808 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 125973377 Common - Rubrerythrin Cthe_0860 80 COG1592 COG1592, Rubrerythrin Energy production and conversion 125975390 Common - ribosomal protein S3 Cthe_2909 248 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 125973395 Common - CheW protein Cthe_0878 126 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 125973721 Common - Integrase, catalytic region Cthe_1206 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 125974395 Nonpathogen - hypothetical protein Cthe_1891 1 None None None 125974945 Common - transcriptional regulator, XRE family Cthe_2460 27 COG1396 HipB, Predicted transcriptional regulators Transcription 125974565 Common - protein of unknown function DUF28 Cthe_2075 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 125972540 Common - alpha-L-arabinofuranosidase B Cthe_0015 21 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 125973064 Nonpathogen - prepilin peptidase CpaA Cthe_0545 5 COG4960 CpaA, Flp pilus assembly protein, protease CpaA Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 125973835 Common - ribosomal protein L11 methyltransferase Cthe_1320 187 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 125973312 Common - aluminium resistance protein Cthe_0794 33 COG4100 COG4100, Cystathionine beta-lyase family protein involved in aluminum resistance Inorganic ion transport and metabolism 125974151 Common - conserved hypothetical phage-associated protein Cthe_1645 5 None None None 125973074 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Cthe_0555 71 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 125975467 Nonpathogen - hypothetical protein Cthe_2988 1 None None None 125972627 Common - protein of unknown function UPF0047 Cthe_0103 140 COG0432 COG0432, Uncharacterized conserved protein Function unknown 125975063 Common - phosphodiesterase, MJ0936 family Cthe_2580 73 COG0622 COG0622, Predicted phosphoesterase General function prediction only 125973725 Nonpathogen - hypothetical protein Cthe_1210 2 None None None 125973409 Common - protein of unknown function DUF34 Cthe_0892 109 COG0327 COG0327, Uncharacterized conserved protein Function unknown 125975446 Nonpathogen - hypothetical protein Cthe_2966 2 None None None 125973053 Common - ABC-type bacteriocin transporter Cthe_0534 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 125975015 Common - glutamate-1-semialdehyde-2,1-aminomutase Cthe_2530 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 125975064 Common - dihydropteroate synthase Cthe_2581 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 125975614 Common - peptidase S8 and S53, subtilisin, kexin, sedolisin Cthe_3136 82 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 125973777 Nonpathogen - hypothetical protein Cthe_1262 3 None None None 125974491 Common - transposase, mutator type Cthe_1991 88 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 125975340 Common - transposase, mutator type Cthe_2858 89 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974428 Nonpathogen - hypothetical protein Cthe_1927 1 None None None 125974811 Common - protein of unknown function DUF163 Cthe_2326 167 COG1576 COG1576, Uncharacterized conserved protein Function unknown 125973770 Nonpathogen - hypothetical protein Cthe_1255 1 None None None 125974111 Common - phosphate ABC transporter, ATPase subunit Cthe_1602 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 125973220 Nonpathogen - hypothetical protein Cthe_0702 2 None None None 125973924 Common - cation diffusion facilitator family transporter Cthe_1410 213 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 125973507 Common - ribosomal protein L7Ae/L30e/S12e/Gadd45 Cthe_0992 26 COG1358 RPL8A, Ribosomal protein HS6-type (S12/L30/L7a) Translation, ribosomal structure and biogenesis 125972832 Common - excinuclease ABC, A subunit Cthe_0311 235 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 125972677 Common - Holliday junction resolvase YqgF Cthe_0153 177 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 125974803 Common - hypothetical protein Cthe_2318 2 COG4848 COG4848, Uncharacterized protein conserved in bacteria Function unknown 125973640 Common - hypothetical protein Cthe_1125 2 None None None 125972989 Common - flagellar protein export ATPase FliI Cthe_0468 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 125972760 Nonpathogen - hypothetical protein Cthe_0238 1 None None None 125974946 Common - transcriptional regulator, XRE family Cthe_2461 11 COG1476 COG1476, Predicted transcriptional regulators Transcription 125973035 Common - transposase IS66 Cthe_0515 63 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974760 Common - hypothetical protein Cthe_2275 9 COG1106 COG1106, Predicted ATPases General function prediction only 125973201 Common - diaminopimelate decarboxylase Cthe_0683 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 125974387 Common - SMC protein-like protein Cthe_1883 76 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 125973953 Nonpathogen - hypothetical protein Cthe_1440 2 None None None 125974417 Common - periplasmic sensor signal transduction histidine kinase Cthe_1915 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 125974118 Common - Peptidoglycan-binding LysM Cthe_1611 25 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 125975175 Nonpathogen - hypothetical protein Cthe_2693 1 None None None 125975357 Common - ATP-dependent DNA helicase PcrA Cthe_2876 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 125972792 Common - glycoside hydrolase, family 18 Cthe_0270 46 COG3325 ChiA, Chitinase Carbohydrate transport and metabolism 125974840 Common - L-aspartate oxidase Cthe_2355 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 125972842 Nonpathogen - TPR repeat domain containing protein Cthe_0321 2 None None None 125973100 Common - Fibronectin-binding A-like protein Cthe_0581 92 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 125975136 Common - PHP-like protein Cthe_2654 40 COG4464 CapC, Capsular polysaccharide biosynthesis protein Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 125974861 Common - DNA gyrase, B subunit Cthe_2376 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 125975458 Common - transcriptional regulator, Crp/Fnr family Cthe_2978 114 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 125975674 Nonpathogen - Uncharacterized conserved protein UCP033563 Cthe_3196 3 COG4198 COG4198, Uncharacterized conserved protein Function unknown 125973515 Common - phosphatidate cytidylyltransferase Cthe_1000 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 125975280 Common - putative endoribonuclease L-PSP Cthe_2798 193 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 125973229 Common - chorismate mutase Cthe_0711 38 COG4401 AroH, Chorismate mutase Amino acid transport and metabolism 125974742 Common - ribosomal protein L9 Cthe_2257 215 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 125973177 Nonpathogen - hypothetical protein Cthe_0659 5 None None None 125975012 Common - porphobilinogen deaminase Cthe_2527 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 125973065 Common - ferric uptake regulator, Fur family Cthe_0546 197 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 125973979 Nonpathogen - hypothetical protein Cthe_1467 1 COG2378 COG2378, Predicted transcriptional regulator Transcription 125975535 Common - transposase, IS204/IS1001/IS1096/IS1165 Cthe_3056 39 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974476 Common - transposase IS3/IS911 Cthe_1975 39 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 125972956 Nonpathogen - cellulosome enzyme, dockerin type I Cthe_0435 1 None None None 125974545 Common - hypothetical protein Cthe_2055 17 COG1353 COG1353, Predicted hydrolase of the HD superfamily (permuted catalytic motifs) General function prediction only 125974876 Common - pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit Cthe_2391 71 COG1144 COG1144, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit Energy production and conversion 125972775 Common - ATPase associated with various cellular activities, AAA_3 Cthe_0253 179 COG0714 COG0714, MoxR-like ATPases General function prediction only 125975268 Common - methylcobalamin:coenzyme M methyltransferase Cthe_2786 29 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 125973808 Common - metal dependent phosphohydrolase Cthe_1293 108 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 125974747 Common - V-type ATPase, 116 kDa subunit Cthe_2262 51 COG1269 NtpI, Archaeal/vacuolar-type H+-ATPase subunit I Energy production and conversion 125974973 Common - phage tape measure protein Cthe_2488 31 COG5281 COG5281, Phage-related minor tail protein Function unknown 125973382 Common - 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) Cthe_0865 109 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 125973994 Common - Cof-like hydrolase Cthe_1482 109 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 125975131 Nonpathogen - HpcH/HpaI aldolase Cthe_2649 4 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 125973735 Nonpathogen - hypothetical protein Cthe_1220 1 None None None 125975647 Common - short-chain dehydrogenase/reductase SDR Cthe_3169 231 COG0623 FabI, Enoyl- acyl-carrier-protein 125975352 Common - TipAS antibiotic-recognition Cthe_2871 28 None None None 125973088 Common - protein of unknown function DUF116 Cthe_0569 29 COG1852 COG1852, Uncharacterized conserved protein Function unknown 125974767 Common - MCP methyltransferase, CheR-type Cthe_2282 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 125974310 Nonpathogen - cellulosome enzyme, dockerin type I Cthe_1806 4 COG1361 COG1361, S-layer domain Cell envelope biogenesis, outer membrane 125973206 Common - putative transcriptional regulator Cthe_0688 161 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 125975565 Common - 3-phosphoshikimate 1-carboxyvinyltransferase Cthe_3086 238 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 125973769 Common - hypothetical protein Cthe_1254 4 None None None 125975713 Nonpathogen - hypothetical protein Cthe_3235 2 None None None 125974380 Common - Tn7-like transposition protein A Cthe_1876 18 None None None 125974784 Common - CRISPR-associated helicase Cas3 Cthe_2299 114 COG1203 COG1203, Predicted helicases General function prediction only 125974794 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Cthe_2309 203 COG0388 COG0388, Predicted amidohydrolase General function prediction only 125975005 Nonpathogen - hypothetical protein Cthe_2520 1 None None None 125973309 Common - protein of unknown function DUF552 Cthe_0791 55 COG1799 COG1799, Uncharacterized protein conserved in bacteria Function unknown 125973602 Nonpathogen - hypothetical protein Cthe_1087 1 None None None 125973681 Common - protein of unknown function DUF147 Cthe_1166 67 COG1624 COG1624, Uncharacterized conserved protein Function unknown 125973535 Common - extracellular solute-binding protein, family 1 Cthe_1020 113 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 125973785 Common - proteinase inhibitor I4, serpin Cthe_1270 31 COG4826 COG4826, Serine protease inhibitor Posttranslational modification, protein turnover, chaperones 125975142 Common - hypothetical protein Cthe_2660 10 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 125975512 Nonpathogen - hypothetical protein Cthe_3033 1 None None None 125975684 Nonpathogen - hypothetical protein Cthe_3206 4 None None None 125975590 Common - glycosidase, PH1107-related Cthe_3112 35 COG2152 COG2152, Predicted glycosylase Carbohydrate transport and metabolism 125974180 Common - Integrase, catalytic region Cthe_1674 153 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973847 Common - histidyl-tRNA synthetase Cthe_1332 249 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 125975470 Common - NADH:flavin oxidoreductase/NADH oxidase Cthe_2991 216 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 125975127 Common - NAD-dependent epimerase/dehydratase Cthe_2645 234 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 125975395 Common - ribosomal protein L24 Cthe_2914 202 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 125975243 Common - glycoside hydrolase, family 9 Cthe_2761 19 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 125974775 Common - ABC transporter related protein Cthe_2290 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 125975681 Common - CRISPR-associated protein Cas5, Hmari subtype Cthe_3203 18 None None None 125973751 Common - Fibronectin, type III Cthe_1236 11 COG3979 COG3979, Uncharacterized protein contain chitin-binding domain type 3 General function prediction only 125972969 Common - sporulation sigma factor SigG Cthe_0448 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 125973436 Common - Integrase, catalytic region Cthe_0919 153 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974695 Common - 3-isopropylmalate dehydratase, small subunit Cthe_2210 208 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 125974721 Common - flagellin-like protein Cthe_2236 116 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 125975546 Common - membrane spanning protein Cthe_3067 8 None None None 125974107 Common - nitroreductase Cthe_1598 4 None None None 125974655 Common - hypothetical protein Cthe_2170 9 None None None 125974168 Common - transposase IS3/IS911 Cthe_1662 39 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973431 Common - hypothetical protein Cthe_0914 25 COG5373 COG5373, Predicted membrane protein Function unknown 125974532 Common - ATP-dependent exonuclease synthesis protein AddB (superfamily I helicase) Cthe_2040 30 COG3857 AddB, ATP-dependent nuclease, subunit B DNA replication, recombination, and repair 125973477 Common - SpoIID/LytB domain containing protein Cthe_0960 48 COG2385 SpoIID, Sporulation protein and related proteins Cell division and chromosome partitioning 125975544 Common - hypothetical protein Cthe_3065 2 None None None 125975335 Common - prophage Lp4 protein 7, DNA replication Cthe_2853 15 None None None 125975211 Common - translation elongation factor G Cthe_2729 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 125975219 Common uvrC excinuclease ABC subunit C Cthe_2737 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 125973482 Common - ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Cthe_0965 142 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 125973864 Common - Undecaprenyl-phosphate galactose phosphotransferase Cthe_1349 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 125972701 Nonpathogen - hypothetical protein Cthe_0177 1 None None None 125972641 Common - HPrNtr domain containing protein Cthe_0117 128 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 125974347 Common - transcriptional regulator, BadM/Rrf2 family Cthe_1843 170 COG1959 COG1959, Predicted transcriptional regulator Transcription 125975310 Nonpathogen - hypothetical protein Cthe_2828 1 None None None 125973318 Common - periplasmic sensor signal transduction histidine kinase Cthe_0800 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 125973246 Common xerC site-specific tyrosine recombinase XerC Cthe_0728 228 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 125973410 Common - protein of unknown function DUF633 Cthe_0893 32 COG2384 COG2384, Predicted SAM-dependent methyltransferase General function prediction only 125974447 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Cthe_1946 249 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 125974881 Nonpathogen - hypothetical protein Cthe_2396 1 None None None 125974874 Common - sigmaK-factor processing regulatory BofA Cthe_2389 8 None None None 125975123 Common - N-acylneuraminate-9-phosphate synthase Cthe_2641 78 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 125973522 Common - GTP-binding protein TypA Cthe_1007 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 125973239 Common - nitrogen-fixing NifU-like protein Cthe_0721 157 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 125972532 Nonpathogen - hypothetical protein Cthe_0007 1 None None None 125975100 Common - peptidase M23B Cthe_2617 187 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 125974438 Common - glutamate racemase Cthe_1937 191 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 125973160 Common - hypothetical protein Cthe_0642 4 None None None 125975107 Common - beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ Cthe_2625 189 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 125972803 Nonpathogen - hypothetical protein Cthe_0281 1 None None None 125974916 Common - electron transport complex, RnfABCDGE type, D subunit Cthe_2431 76 COG4658 RnfD, Predicted NADH:ubiquinone oxidoreductase, subunit RnfD Energy production and conversion 125975029 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Cthe_2544 167 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 125974966 Common - hypothetical protein Cthe_2481 1 None None None 125974081 Common - ABC transporter related protein Cthe_1572 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 125975438 Nonpathogen - hypothetical protein Cthe_2957 1 None None None 125974751 Common - V-type ATP synthase subunit F Cthe_2266 7 COG1436 NtpG, Archaeal/vacuolar-type H+-ATPase subunit F Energy production and conversion 125974335 Nonpathogen - hypothetical protein Cthe_1831 1 None None None 125974273 Nonpathogen - hypothetical protein Cthe_1769 1 None None None 125974550 Common - RNA methyltransferase, TrmH family, group 3 Cthe_2060 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 125974846 Common - DNA gyrase, A subunit Cthe_2361 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 125974915 Common - electron transport complex, RnfABCDGE type, C subunit Cthe_2430 121 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 125975190 Common - hypothetical protein Cthe_2708 23 COG3225 GldG, ABC-type uncharacterized transport system involved in gliding motility, auxiliary component Cell motility and secretion 125974922 Common - shikimate kinase Cthe_2437 199 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 125972711 Common - hypothetical protein Cthe_0187 15 COG5401 COG5401, Spore germination protein General function prediction only 125974223 Common - phage major capsid protein, HK97 family Cthe_1719 20 None None None 125973545 Common - TPR repeat domain containing protein Cthe_1030 37 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 125975701 Nonpathogen - hypothetical protein Cthe_3223 1 None None None 125972850 Common - hypothetical protein Cthe_0329 17 None None None 125974071 Common - protein of unknown function DUF214 Cthe_1562 33 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 125973910 Common - phospholipase D/Transphosphatidylase Cthe_1396 151 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 125975554 Common - von Willebrand factor, type A Cthe_3075 47 COG2304 COG2304, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 125972875 Common - putative CoA-substrate-specific enzyme activase Cthe_0354 65 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 125974264 Common - penicillin-binding protein, 1A family Cthe_1760 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 125973943 Common - hypothetical protein Cthe_1429 4 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 125974505 Common - conserved hypothetical protein, CF-22 family Cthe_2008 3 None None None 125974700 Common - Mg2+ transporter protein, CorA-like protein Cthe_2215 42 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 125974363 Common - protein of unknown function DUF214 Cthe_1859 115 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 125975580 Common - cell envelope-related transcriptional attenuator Cthe_3102 64 COG1316 LytR, Transcriptional regulator Transcription 125973683 Common - hypothetical protein Cthe_1168 76 COG3885 COG3885, Uncharacterized conserved protein Function unknown 125973155 Common - protein of unknown function DUF909 Cthe_0637 7 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 125975486 Common - ErfK/YbiS/YcfS/YnhG Cthe_3007 46 COG3858 COG3858, Predicted glycosyl hydrolase General function prediction only 125973140 Common - methylthioadenosine phosphorylase Cthe_0622 163 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 125973346 Common - deoxyxylulose-5-phosphate synthase Cthe_0828 230 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 125973292 Common - RNA chaperone Hfq Cthe_0774 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 125974091 Common - cytidine deaminase Cthe_1582 121 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 125974936 Common - SNF2-related protein Cthe_2451 130 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 125973021 Nonpathogen - hypothetical protein Cthe_0501 1 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 125974892 Common - AAA ATPase, central region Cthe_2407 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 125974309 Common - diguanylate cyclase Cthe_1805 225 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 125972528 Common - ankyrin repeat protein Cthe_0003 13 None None None 125973299 Common - GCN5-related N-acetyltransferase Cthe_0781 29 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 125972874 Common - hypothetical protein Cthe_0353 25 COG3581 COG3581, Uncharacterized protein conserved in bacteria Function unknown 125973883 Common - S-layer-like domain containing protein Cthe_1368 22 None None None 125972757 Common - Glutaredoxin-like protein, YruB-family Cthe_0235 102 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 125972593 Common - asparagine synthetase AsnA Cthe_0069 32 COG2502 AsnA, Asparagine synthetase A Amino acid transport and metabolism 125973696 Common - transglutaminase-like protein Cthe_1181 95 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 125974561 Common - hypothetical protein Cthe_2071 15 None None None 125973670 Nonpathogen - hypothetical protein Cthe_1155 1 COG2359 SpoVS, Uncharacterized protein conserved in bacteria Function unknown 125973938 Common - hypothetical protein Cthe_1424 14 None None None 125974008 Nonpathogen - hypothetical protein Cthe_1497 1 None None None 125973580 Nonpathogen - type IV pilus assembly PilZ Cthe_1065 1 None None None 161485635 Common - stage V sporulation protein AD Cthe_0123 15 None None None 125973169 Nonpathogen - hypothetical protein Cthe_0651 1 None None None 125973917 Common - FeoA Cthe_1403 37 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 125975364 Common - histidinol-phosphate aminotransferase Cthe_2883 241 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 125973645 Nonpathogen - hypothetical protein Cthe_1130 1 None None None 125973287 Common rpsP 30S ribosomal protein S16 Cthe_0769 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 125975712 Nonpathogen - hypothetical protein Cthe_3234 1 None None None 125974899 Common - Monogalactosyldiacylglycerol synthase Cthe_2414 43 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 125975319 Common - prophage Lp4 protein 7, DNA replication Cthe_2837 10 None None None 125975075 Nonpathogen - hypothetical protein Cthe_2592 1 None None None 125975567 Nonpathogen - UspA Cthe_3089 10 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 125974818 Common - two component transcriptional regulator, winged helix family Cthe_2333 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 125972903 Nonpathogen - hypothetical protein Cthe_0382 1 None None None 125974138 Common - hypothetical protein Cthe_1631 36 None None None 125974598 Common - Orn/Lys/Arg decarboxylase, major region Cthe_2108 91 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 125972828 Nonpathogen - hypothetical protein Cthe_0307 4 None None None 125973896 Common - threonine synthase Cthe_1381 131 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 125974497 Nonpathogen - hypothetical protein Cthe_1997 2 None None None 125973817 Common - hypothetical protein Cthe_1302 153 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 125972619 Common - methylglyoxal synthase Cthe_0095 82 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 125972845 Common valS valyl-tRNA synthetase Cthe_0324 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 125974410 Common - copper amine oxidase-like protein Cthe_1908 29 None None None 125974422 Common - stage II sporulation protein R Cthe_1920 15 None None None 125975646 Common - putative lipid kinase Cthe_3168 89 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 125973792 Common - putative methyltransferase Cthe_1277 218 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 125974370 Common - acetylornithine and succinylornithine aminotransferases Cthe_1866 238 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 125974121 Nonpathogen - hypothetical protein Cthe_1614 3 None None None 125975054 Nonpathogen - hypothetical protein Cthe_2570 1 None None None 125975578 Common - Diaminopimelate epimerase Cthe_3100 204 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 125972890 Common - protein of unknown function DUF111 Cthe_0369 64 COG1641 COG1641, Uncharacterized conserved protein Function unknown 125973321 Common - pseudouridine synthase, RluA family Cthe_0803 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 125975162 Common - peptidase S41 Cthe_2680 203 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 125972567 Common - glycoside hydrolase, family 9 Cthe_0043 19 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 125972862 Common - NADH dehydrogenase (quinone) Cthe_0341 187 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 125974859 Common - DNA replication and repair protein RecF Cthe_2374 177 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 125973625 Common - protein tyrosine phosphatase Cthe_1110 133 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 125974738 Common - ATP-dependent metalloprotease FtsH Cthe_2253 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 125973577 Common - VanW Cthe_1062 39 COG2720 COG2720, Uncharacterized vancomycin resistance protein Defense mechanisms 125974618 Common - hypothetical protein Cthe_2130 9 COG3595 COG3595, Uncharacterized conserved protein Function unknown 125975369 Common - imidazoleglycerol phosphate synthase, cyclase subunit Cthe_2888 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 125973585 Common - metal dependent phosphohydrolase Cthe_1070 56 COG1480 COG1480, Predicted membrane-associated HD superfamily hydrolase General function prediction only 125974594 Common - PSP1 Cthe_2104 58 COG1774 COG1774, Uncharacterized homolog of PSP1 Function unknown 125974157 Nonpathogen - hypothetical protein Cthe_1651 3 None None None 125974402 Common - Serine-type D-Ala-D-Ala carboxypeptidase Cthe_1899 37 COG1876 VanY, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 125974088 Common - ABC transporter related protein Cthe_1579 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 125975505 Common - GreA/GreB family elongation factor Cthe_3026 12 COG0782 GreA, Transcription elongation factor Transcription 125975662 Common - cation transporter Cthe_3184 123 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 125973673 Nonpathogen - hypothetical protein Cthe_1158 1 None None None 125974025 Common - protein of unknown function DUF125, transmembrane Cthe_1514 28 COG1814 COG1814, Uncharacterized membrane protein Function unknown 125972555 Nonpathogen - putative membrane transporter Cthe_0031 3 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 125974442 Nonpathogen - putative regulatory protein, FmdB family Cthe_1941 6 COG2331 COG2331, Uncharacterized protein conserved in bacteria Function unknown 125974317 Common - urease accessory protein UreG Cthe_1813 155 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 125974294 Common - ATP:guanido phosphotransferase Cthe_1790 25 COG3869 COG3869, Arginine kinase Amino acid transport and metabolism 125973900 Common secA preprotein translocase subunit SecA Cthe_1385 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 125974029 Common - hypothetical protein Cthe_1518 1 None None None 125973592 Nonpathogen - hypothetical protein Cthe_1077 1 None None None 125974057 Common - hypothetical protein Cthe_1547 9 None None None 125974486 Common - phage major capsid protein, HK97 Cthe_1985 14 COG4653 COG4653, Predicted phage phi-C31 gp36 major capsid-like protein General function prediction only 125973408 Common - response regulator receiver protein Cthe_0891 204 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 125973009 Common - type IV pilus assembly PilZ Cthe_0488 13 COG5581 COG5581, Predicted glycosyltransferase Cell envelope biogenesis, outer membrane 125974234 Common - hypothetical protein Cthe_1730 2 None None None 125974458 Common - extracellular solute-binding protein, family 1 Cthe_1957 29 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 125974159 Common - SNF2-related protein Cthe_1653 107 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 125975119 Common - glycosyl transferase, group 1 Cthe_2637 226 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 125973565 Common - recA protein Cthe_1050 240 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 125973417 Common - aspartate 1-decarboxylase Cthe_0900 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 125972887 Nonpathogen - hypothetical protein Cthe_0366 1 None None None 125975693 Common - CRISPR-associated protein, TM1812 family Cthe_3215 17 None None None 125974449 Common - cytochrome c biogenesis protein, transmembrane region Cthe_1948 75 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 125973072 Common - transcriptional regulator, LysR family Cthe_0553 193 COG0583 LysR, Transcriptional regulator Transcription 125975034 Common - glycosyltransferase sugar-binding region containing DXD motif Cthe_2550 10 COG3774 OCH1, Mannosyltransferase OCH1 and related enzymes Cell envelope biogenesis, outer membrane 125972814 Common - transposase, mutator type Cthe_0292 88 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973366 Common - peptidase M24 Cthe_0848 231 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 125972689 Common - hypothetical protein Cthe_0165 4 None None None 125974175 Common - DNA recombinase, putative Cthe_1669 10 None None None 125973370 Common - type II secretion system protein E Cthe_0853 176 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 125973193 Common - hypothetical protein Cthe_0675 15 COG1300 SpoIIM, Uncharacterized membrane protein Function unknown 125972610 Nonpathogen - hypothetical protein Cthe_0086 1 None None None 125973256 Common - copper ion binding protein Cthe_0738 112 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 125973702 Common - protein of unknown function DUF990 Cthe_1187 35 COG4587 COG4587, ABC-type uncharacterized transport system, permease component General function prediction only 125975407 Nonpathogen - hypothetical protein Cthe_2926 6 COG2163 RPL14A, Ribosomal protein L14E/L6E/L27E Translation, ribosomal structure and biogenesis 125972737 Common - protein of unknown function DUF975 Cthe_0213 9 COG5523 COG5523, Predicted integral membrane protein Function unknown 125972631 Common ribH riboflavin synthase subunit beta Cthe_0107 230 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 125974535 Common - conserved hypothetical protein precursor Cthe_2045 15 None None None 125975519 Common - hypothetical protein Cthe_3040 4 COG1633 COG1633, Uncharacterized conserved protein Function unknown 125973650 Common - SEFIR domain containing protein Cthe_1135 10 None None None 125975293 Common - glycoside hydrolase, family 26 Cthe_2811 9 COG4124 ManB, Beta-mannanase Carbohydrate transport and metabolism 125974210 Nonpathogen - hypothetical protein Cthe_1706 2 None None None 125973492 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase Cthe_0977 214 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 125974036 Common - protein of unknown function DUF214 Cthe_1525 17 None None None 125975631 Common - Phosphoglycerate mutase Cthe_3153 197 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 125974954 Nonpathogen - phage transcriptional regulator, RinA family Cthe_2469 2 None None None 125974645 Common - hypothetical protein Cthe_2160 7 None None None 125975388 Common rpsS 30S ribosomal protein S19 Cthe_2907 246 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 125974838 Nonpathogen - PGAP1-like protein Cthe_2353 4 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 125974832 Common - lipopolysaccharide biosynthesis Cthe_2347 39 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 125973361 Common - Stage III sporulation AC Cthe_0843 15 None None None 125973814 Nonpathogen - hypothetical protein Cthe_1299 1 None None None 125973749 Common - methyl-accepting chemotaxis sensory transducer Cthe_1234 153 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 125974688 Common folE GTP cyclohydrolase I Cthe_2203 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 125972910 Common - PfkB Cthe_0389 193 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 125975510 Common - hypothetical protein Cthe_3031 3 None None None 125974379 Common - HMG-I and HMG-Y, DNA-binding Cthe_1875 14 None None None 125973008 Common - Cobyrinic acid a,c-diamide synthase Cthe_0487 162 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 125974825 Common - UDP-glucose/GDP-mannose dehydrogenase Cthe_2340 207 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 125974203 Nonpathogen - hypothetical protein Cthe_1698 3 None None None 125974640 Common - Methyltransferase type 11 Cthe_2154 82 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 125972545 Common - biotin synthase Cthe_0020 180 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 125973004 Common fliR flagellar biosynthesis protein FliR Cthe_0483 129 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 125973077 Nonpathogen - hypothetical protein Cthe_0558 3 None None None 125973294 Common - DNA mismatch repair protein MutL Cthe_0776 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 125973854 Common - type II secretion system protein E Cthe_1339 228 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 125974141 Common - hypothetical protein Cthe_1635 13 None None None 125974689 Common - cyanophycin synthetase Cthe_2204 187 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 125973555 Common - DNA polymerase III, delta subunit Cthe_1040 51 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 125973764 Common - amidophosphoribosyltransferase Cthe_1249 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 125972935 Common - manganese containing catalase Cthe_0414 46 COG3546 COG3546, Mn-containing catalase Inorganic ion transport and metabolism 125974342 Common - glycoside hydrolase, family 10 Cthe_1838 34 COG3693 XynA, Beta-1,4-xylanase Carbohydrate transport and metabolism 125975537 Common - hypothetical protein Cthe_3058 11 None None None 125972745 Nonpathogen - hypothetical protein Cthe_0221 1 None None None 125973460 Common - hypothetical protein Cthe_0943 3 None None None 125973960 Nonpathogen - hypothetical protein Cthe_1447 1 None None None 125974040 Common - transposase, IS204/IS1001/IS1096/IS1165 Cthe_1530 20 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974254 Common - hypothetical protein Cthe_1750 4 None None None 125974014 Common - hypothetical protein Cthe_1503 26 COG1633 COG1633, Uncharacterized conserved protein Function unknown 125974635 Common - hypothetical protein Cthe_2149 36 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 125975376 Common - glycoside hydrolase, family 18 Cthe_2895 37 COG3858 COG3858, Predicted glycosyl hydrolase General function prediction only 125975439 Common - transposase, mutator type Cthe_2958 88 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974660 Nonpathogen - hypothetical protein Cthe_2175 8 None None None 125973428 Common - protein of unknown function DUF152 Cthe_0911 180 COG1496 COG1496, Uncharacterized conserved protein Function unknown 125974854 Common - ribonuclease P protein component Cthe_2369 77 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 125975432 Nonpathogen - hypothetical protein Cthe_2951 1 None None None 125975339 Nonpathogen - hypothetical protein Cthe_2857 1 None None None 125973967 Common - hypothetical protein Cthe_1455 8 COG4912 COG4912, Predicted DNA alkylation repair enzyme DNA replication, recombination, and repair 125974163 Common - transposase IS3/IS911 Cthe_1657 39 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973941 Common - branched-chain amino acid transport Cthe_1427 12 COG4392 COG4392, Predicted membrane protein Function unknown 125972679 Common - hypothetical protein Cthe_0155 14 None None None 125973237 Common - transcriptional regulator, BadM/Rrf2 family Cthe_0719 177 COG1959 COG1959, Predicted transcriptional regulator Transcription 125972979 Common - exodeoxyribonuclease III Xth Cthe_0458 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 125975706 Common - copper amine oxidase-like protein Cthe_3228 10 None None None 125975473 Nonpathogen - hypothetical protein Cthe_2994 1 None None None 125975496 Common - hydrogenase accessory protein HypB Cthe_3017 143 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 125972929 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) Cthe_0408 201 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 125972662 Common pgk phosphoglycerate kinase Cthe_0138 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 125973351 Common - exodeoxyribonuclease VII, large subunit Cthe_0833 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 125973772 Common - Carbohydrate-binding, CenC-like protein Cthe_1257 12 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 125974265 Common - protein of unknown function DUF214 Cthe_1761 151 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 125972865 Common - Malate dehydrogenase (oxaloacetate-decarboxylating) Cthe_0344 202 COG0281 SfcA, Malic enzyme Energy production and conversion 125972690 Common - 4Fe-4S ferredoxin, iron-sulfur binding Cthe_0166 137 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 125973655 Nonpathogen - hypothetical protein Cthe_1140 1 None None None 125973494 Common - Peptidoglycan glycosyltransferase Cthe_0979 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 125974693 Common - LexA DNA-binding region containing protein Cthe_2208 80 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 125973616 Nonpathogen - hypothetical protein Cthe_1101 1 None None None 125974529 Common - amidohydrolase 2 Cthe_2036 26 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 125973807 Common - proposed homoserine kinase Cthe_1292 57 COG3635 COG3635, Predicted phosphoglycerate mutase, AP superfamily Carbohydrate transport and metabolism 125975093 Common - hypothetical protein Cthe_2610 9 None None None 125975183 Common - glycosyl transferase, WecB/TagA/CpsF family Cthe_2701 113 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 125974661 Common - Abortive infection protein Cthe_2176 63 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 125972643 Common - anti-sigma F factor Cthe_0119 37 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 125975026 Common - nitrite and sulphite reductase 4Fe-4S region Cthe_2541 184 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 125974287 Common rplM 50S ribosomal protein L13 Cthe_1783 235 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 125974902 Common - Abortive infection protein Cthe_2417 37 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 125974068 Common - Cystathionine gamma-synthase Cthe_1559 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 125975623 Common - transcriptional repressor, CopY family Cthe_3145 15 COG3682 COG3682, Predicted transcriptional regulator Transcription 125974624 Common - cellulosome enzyme, dockerin type I Cthe_2137 7 None None None 125975234 Common - beta-lactamase-like protein Cthe_2752 129 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 125975622 Common - transcriptional regulator, AraC family Cthe_3144 85 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 125973779 Common dnaE DNA polymerase III DnaE Cthe_1264 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 125974969 Common - transposase IS116/IS110/IS902 Cthe_2484 95 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 125972770 Common - transposase, IS4 Cthe_0248 28 None None None 125975528 Common - TPR repeat domain containing protein Cthe_3049 160 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 125973179 Common - Ricin B lectin Cthe_0661 26 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 125974519 Common - Resolvase helix-turn-helix region containing protein Cthe_2025 34 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 125974960 Common - phage portal protein, SPP1 family Cthe_2475 10 None None None 125974715 Common - acylneuraminate cytidylyltransferase Cthe_2230 56 COG1861 SpsF, Spore coat polysaccharide biosynthesis protein F, CMP-KDO synthetase homolog Cell envelope biogenesis, outer membrane 125975287 Common - Carbohydrate-binding, CenC-like protein Cthe_2805 2 None None None 125973349 Common - Polyprenyl synthetase Cthe_0831 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 125974675 Common - N-acetylglucosamine-6-phosphate deacetylase Cthe_2190 123 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 125974333 Nonpathogen - Chromosome segregation ATPases-like protein Cthe_1829 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 125973119 Common - thiamine-phosphate pyrophosphorylase Cthe_0601 208 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 125975148 Common - ATPase, P-type (transporting), HAD superfamily, subfamily IC Cthe_2666 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 125974498 Common - conserved hypothetical protein precursor Cthe_1998 18 None None None 125975605 Common - peptidase M56, BlaR1 Cthe_3127 31 COG4219 MecR1, Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component Transcription / Signal transduction mechanisms 125974934 Common - Phosphoglycerate mutase Cthe_2449 192 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 125973456 Nonpathogen - hypothetical protein Cthe_0939 1 None None None 125973572 Common - phage shock protein C, PspC Cthe_1057 23 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 125974352 Common - copper-translocating P-type ATPase Cthe_1848 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 125973447 Common - Radical SAM Cthe_0930 107 COG1243 ELP3, Histone acetyltransferase Transcription / Chromatin structure and dynamics 125974049 Common - glutamine synthetase, catalytic region Cthe_1539 139 COG3968 COG3968, Uncharacterized protein related to glutamine synthetase General function prediction only 125975274 Common - Phenylacetate--CoA ligase Cthe_2792 120 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 125972654 Common - 3-oxoacyl-(acyl-carrier-protein) synthase Cthe_0130 198 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 125973780 Common - phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I Cthe_1265 238 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 125973633 Nonpathogen - hypothetical protein Cthe_1118 1 None None None 125975651 Common - sodium/calcium exchanger membrane region Cthe_3173 72 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 125975312 Common - IstB-like ATP-binding protein Cthe_2830 98 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 125972897 Common - transcriptional repressor, CopY family Cthe_0376 32 COG3682 COG3682, Predicted transcriptional regulator Transcription 125974219 Common - phage protein, HK97 gp10 family Cthe_1715 4 None None None 125974359 Common - Methyltransferase type 11 Cthe_1855 59 COG4976 COG4976, Predicted methyltransferase (contains TPR repeat) General function prediction only 125975663 Common - tRNA-guanine transglycosylases, various specificities Cthe_3185 123 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 125972900 Nonpathogen - hypothetical protein Cthe_0379 1 None None None 125972924 Common - putative RNA polymerase sigma factor SigI Cthe_0403 14 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 125973713 Nonpathogen - hypothetical protein Cthe_1198 1 None None None 125975301 Common - methyl-accepting chemotaxis sensory transducer Cthe_2819 186 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 125973170 Common - 4-oxalocrotonate tautomerase Cthe_0652 16 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 125972529 Common - YD repeat containing protein Cthe_0004 79 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 125974516 Nonpathogen - hypothetical protein Cthe_2021 1 None None None 125974130 Common - phage major tail protein, phi13 family Cthe_1623 9 None None None 125973333 Common - arginine repressor, ArgR Cthe_0815 65 COG1438 ArgR, Arginine repressor Transcription 125974182 Common - Integrase, catalytic region Cthe_1676 153 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 125972948 Common - serine phosphatase Cthe_0427 10 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 125972853 Common - phosphoribulokinase/uridine kinase Cthe_0332 209 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 125974729 Common - flagellar hook-associated protein FlgK Cthe_2244 124 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 125975220 Common - metallophosphoesterase Cthe_2738 15 COG1768 COG1768, Predicted phosphohydrolase General function prediction only 125974241 Nonpathogen - phage NTP-binding protein Cthe_1737 4 None None None 125972558 Common - cyclic nucleotide-binding protein Cthe_0034 44 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 125974958 Common - Terminase small subunit Cthe_2473 14 COG3728 XtmA, Phage terminase, small subunit DNA replication, recombination, and repair 125974990 Common - transcriptional regulator, LacI family Cthe_2505 124 COG1609 PurR, Transcriptional regulators Transcription 125973870 Common - glycosyl transferase, family 2 Cthe_1355 203 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 125974723 Common - aldehyde dehydrogenase Cthe_2238 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 125973879 Common - hypothetical protein Cthe_1364 1 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 125972843 Common - glycoside hydrolase, family 3-like protein Cthe_0322 184 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 125973307 Common - RNA-binding S4 Cthe_0789 32 COG2302 COG2302, Uncharacterized conserved protein, contains S4-like domain Function unknown 125974653 Nonpathogen - Propeptide, PepSY amd peptidase M4 Cthe_2168 10 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 125975415 Common - ABC transporter related protein Cthe_2934 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 125973604 Common - Stage V sporulation protein S Cthe_1089 24 COG2359 SpoVS, Uncharacterized protein conserved in bacteria Function unknown 125975291 Common - glycoside hydrolase, family 16 Cthe_2809 70 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 125972980 Common - DNA protecting protein DprA Cthe_0459 211 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 125973845 Common - signal peptidase I Cthe_1330 169 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 125974216 Common - Integrase, catalytic region Cthe_1712 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 125973856 Common - coproporphyrinogen III oxidase Cthe_1341 208 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 125972967 Common - peptidase U4, sporulation factor SpoIIGA Cthe_0446 15 None None None 125975514 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Cthe_3035 230 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 125974221 Common - hypothetical protein Cthe_1717 16 None None None 125975265 Common - hypothetical protein Cthe_2783 3 COG5583 COG5583, Uncharacterized small protein Function unknown 125973945 Nonpathogen - hypothetical protein Cthe_1431 2 None None None 125975232 Common - IstB-like ATP-binding protein Cthe_2750 119 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 125974220 Common - phage head-tail adaptor, putative Cthe_1716 16 COG5614 COG5614, Bacteriophage head-tail adaptor General function prediction only 125973866 Common - acetobutylicum phosphotransbutyrylase Cthe_1351 12 COG5652 COG5652, Predicted integral membrane protein Function unknown 125974951 Common - hypothetical protein Cthe_2466 5 None None None 125973449 Common - beta-ketoacyl synthase Cthe_0932 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 125974227 Common - phage terminase, small subunit, putative, P27 family Cthe_1723 22 COG3747 COG3747, Phage terminase, small subunit DNA replication, recombination, and repair 125975039 Common - methyltransferase FkbM family Cthe_2555 18 None None None 125974085 Common - basic membrane lipoprotein Cthe_1576 107 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 125975041 Common - glycosyl transferase, family 2 Cthe_2557 99 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 125972686 Common rpmA 50S ribosomal protein L27 Cthe_0162 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 125973475 Common - queuine tRNA-ribosyltransferase Cthe_0958 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 125975686 Common - Integrase, catalytic region Cthe_3208 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 125974101 Common - Glycerate kinase Cthe_1592 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 125974523 Nonpathogen - hypothetical protein Cthe_2029 1 None None None 125973015 Nonpathogen - hypothetical protein Cthe_0494 1 None None None 125973822 Common - cellulosome anchoring protein, cohesin region Cthe_1307 21 None None None 125973433 Nonpathogen - hypothetical protein Cthe_0916 2 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 125974485 Nonpathogen - hypothetical protein Cthe_1984 1 None None None 125975548 Common - two component transcriptional regulator, winged helix family Cthe_3069 226 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 125974847 Common - parB-like partition protein Cthe_2362 186 COG1475 Spo0J, Predicted transcriptional regulators Transcription 125972603 Common - hypothetical protein Cthe_0079 13 None None None 125972915 Common - iron-containing alcohol dehydrogenase Cthe_0394 177 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 125972708 Common - type IV pilus assembly protein PilM Cthe_0184 50 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 125975217 Common - HPrNtr domain containing protein Cthe_2735 126 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 125972815 Nonpathogen - hypothetical protein Cthe_0293 1 None None None 125974792 Common - hemerythrin-like metal-binding protein Cthe_2307 42 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 125973837 Common - chaperone protein DnaK Cthe_1322 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 125973587 Common - putative stage IV sporulation YqfD Cthe_1072 15 None None None 125975640 Common - SAM dependent methyltransferase Cthe_3162 33 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 125973557 Nonpathogen - hypothetical protein Cthe_1042 1 None None None 125975354 Common - hypothetical protein Cthe_2873 4 None None None 125972834 Common - hypothetical protein Cthe_0313 8 None None None 125975061 Common - Ppx/GppA phosphatase Cthe_2578 183 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 125975168 Common - type IV pilus assembly protein PilM Cthe_2686 95 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 125975114 Common - transcription-repair coupling factor Cthe_2632 240 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 125972629 Common - riboflavin synthase subunit alpha Cthe_0105 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 125973727 Nonpathogen - hypothetical protein Cthe_1212 1 None None None 125973567 Common - competence/damage-inducible protein CinA Cthe_1052 214 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 125974559 Nonpathogen - hypothetical protein Cthe_2069 3 None None None 125974639 Common - Integrase, catalytic region Cthe_2153 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 125973426 Common - lipoprotein signal peptidase Cthe_0909 199 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 125974940 Common - phage integrase Cthe_2455 154 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 125972782 Common - peptidase S1 and S6, chymotrypsin/Hap Cthe_0260 80 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 125973570 Common - protein of unknown function DUF58 Cthe_1055 37 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 125973984 Common - Carbohydrate binding family 11 Cthe_1472 42 COG2730 BglC, Endoglucanase Carbohydrate transport and metabolism 125974735 Nonpathogen - hypothetical protein Cthe_2250 1 None None None 125973951 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Cthe_1438 165 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 125974388 Common - transposase IS116/IS110/IS902 Cthe_1884 95 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974464 Common - glycoside hydrolase, family 10 Cthe_1963 76 COG3693 XynA, Beta-1,4-xylanase Carbohydrate transport and metabolism 125974620 Common - abortive infection protein, putative Cthe_2132 29 COG1106 COG1106, Predicted ATPases General function prediction only 125973310 Common - Protein of unknown function UPF0001 Cthe_0792 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 125973971 Common - hypothetical protein Cthe_1459 2 None None None 125973384 Common - 4Fe-4S ferredoxin, iron-sulfur binding Cthe_0867 80 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 125973509 Common - NusA antitermination factor Cthe_0994 224 COG0195 NusA, Transcription elongation factor Transcription 125973762 Common - phosphoribosylglycinamide formyltransferase Cthe_1247 219 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 125975134 Common - lipopolysaccharide biosynthesis Cthe_2652 36 COG3944 COG3944, Capsular polysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 125975676 Nonpathogen - hypothetical protein Cthe_3198 1 None None None 125975206 Common rpoB DNA-directed RNA polymerase subunit beta Cthe_2724 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 125973166 Common - glutamyl-tRNA synthetase Cthe_0648 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 125974842 Nonpathogen - hypothetical protein Cthe_2357 1 None None None 125974413 Common - Carbohydrate binding family 6 Cthe_1911 13 None None None 125974415 Common - hypothetical protein Cthe_1913 10 COG5291 COG5291, Predicted membrane protein Function unknown 125975649 Nonpathogen - S-layer domain-like protein Cthe_3171 14 COG1361 COG1361, S-layer domain Cell envelope biogenesis, outer membrane 125975471 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Cthe_2992 62 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 125973067 Common - ABC transporter related protein Cthe_0548 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 125974116 Common - Recombinase Cthe_1609 115 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 125974591 Common - Protein of unknown function UPF0011 Cthe_2101 211 COG0313 COG0313, Predicted methyltransferases General function prediction only 125973227 Nonpathogen - hypothetical protein Cthe_0709 1 None None None 125973996 Common - transcriptional regulator Cthe_1484 5 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 125973086 Common def peptide deformylase Cthe_0567 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 125973906 Common - 2-isopropylmalate synthase Cthe_1391 214 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 125972840 Common - class II aldolase/adducin-like protein Cthe_0319 163 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 125973639 Common - phenazine biosynthesis protein PhzF family Cthe_1124 120 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 125974543 Nonpathogen - hypothetical protein Cthe_2053 2 None None None 125974930 Common - Alcohol dehydrogenase GroES-like protein Cthe_2445 214 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 125975448 Common - 4Fe-4S ferredoxin, iron-sulfur binding Cthe_2968 21 COG4635 HemG, Flavodoxin Energy production and conversion / Coenzyme metabolism 125973754 Nonpathogen - hypothetical protein Cthe_1239 1 None None None 125975456 Nonpathogen - hypothetical protein Cthe_2976 1 None None None 125972758 Common - aldo/keto reductase Cthe_0236 204 COG1453 COG1453, Predicted oxidoreductases of the aldo/keto reductase family General function prediction only 125975359 Common - peptidase C39, bacteriocin processing Cthe_2878 12 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 125972620 Nonpathogen - protein of unknown function UPF0180 Cthe_0096 6 None None None 125973069 Common - heat shock protein 90 Cthe_0550 149 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 125973489 Common murG N-acetylglucosaminyl transferase Cthe_0974 211 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 125973732 Common - ATP-dependent Clp protease, ATP-binding subunit clpA Cthe_1217 237 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 125973991 Nonpathogen - hypothetical protein Cthe_1479 1 COG3247 HdeD, Uncharacterized conserved protein Function unknown 125973055 Common - glycoside hydrolase, family 5 Cthe_0536 22 COG2730 BglC, Endoglucanase Carbohydrate transport and metabolism 125973928 Common - hypothetical protein Cthe_1414 1 None None None 125973452 Common - malonyl CoA-acyl carrier protein transacylase Cthe_0935 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 125973733 Common aat leucyl/phenylalanyl-tRNA--protein transferase Cthe_1218 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 125974446 Common - Thioredoxin-disulfide reductase Cthe_1945 247 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 125973185 Common - GerA spore germination protein Cthe_0667 15 None None None 125974749 Common - H+-transporting two-sector ATPase, E subunit Cthe_2264 11 COG1390 NtpE, Archaeal/vacuolar-type H+-ATPase subunit E Energy production and conversion 125973936 Common - RDD domain containing protein Cthe_1422 34 COG3254 COG3254, Uncharacterized conserved protein Function unknown 125975140 Common - RNA-binding S4 Cthe_2658 82 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 125975020 Common - adenylylsulfate reductase, thioredoxin dependent Cthe_2535 167 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 125975571 Common - Adenylosuccinate synthase Cthe_3093 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 125973368 Common - hypothetical protein Cthe_0851 13 None None None 125975083 Common - glycosyl transferase, family 4 Cthe_2600 227 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 125972719 Nonpathogen - RNA polymerase, sigma-24 subunit, ECF subfamily Cthe_0195 1 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 125973406 Nonpathogen - putative transmembrane anti-sigma factor Cthe_0889 6 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 125974743 Common - phosphoesterase, RecJ-like protein Cthe_2258 87 COG3887 COG3887, Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain Signal transduction mechanisms 125974904 Common - primosome, DnaD subunit Cthe_2419 10 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 125973112 Common - transposase, mutator type Cthe_0594 88 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973643 Nonpathogen - hypothetical protein Cthe_1128 1 None None None 125975710 Common - YD repeat protein Cthe_3232 79 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 125973204 Common - tryptophanyl-tRNA synthetase Cthe_0686 249 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 125975405 Common - adenylate kinases Cthe_2924 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 125972576 Common - hypothetical protein Cthe_0052 19 COG1306 COG1306, Uncharacterized conserved protein Function unknown 125973796 Common - hypothetical protein Cthe_1281 1 None None None 125974925 Common - hypothetical protein Cthe_2440 4 None None None 125974890 Common - Heavy metal transport/detoxification protein Cthe_2405 31 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 125972751 Common - NAD-dependent epimerase/dehydratase Cthe_0229 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 125974321 Common - urease, beta subunit Cthe_1817 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 125974801 Nonpathogen - hypothetical protein Cthe_2316 1 None None None 125973698 Common - ATPase associated with various cellular activities, AAA_3 Cthe_1183 173 COG0714 COG0714, MoxR-like ATPases General function prediction only 125975151 Nonpathogen - hypothetical protein Cthe_2669 3 None None None 125975254 Common - transposase IS3/IS911 Cthe_2772 39 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973881 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Cthe_1366 166 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 125974805 Common - DNA-cytosine methyltransferase Cthe_2320 133 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 125975345 Nonpathogen - hypothetical protein Cthe_2864 1 None None None 125973915 Common - hypothetical protein Cthe_1401 4 None None None 125974897 Common - SMC protein-like protein Cthe_2412 93 COG4717 COG4717, Uncharacterized conserved protein Function unknown 125974769 Common - CheA signal transduction histidine kinases Cthe_2284 148 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 125974975 Common - hypothetical protein Cthe_2490 6 None None None 125974136 Common - peptidase S14, ClpP Cthe_1629 69 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 125974816 Nonpathogen - hypothetical protein Cthe_2331 1 None None None 125974365 Common - transcriptional regulator, CdaR Cthe_1861 43 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 125975704 Common - copper amine oxidase-like protein Cthe_3226 10 None None None 125975569 Common - hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta subunit Cthe_3091 146 COG1838 FumA, Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain Energy production and conversion 125973080 Common - ApbE-like lipoprotein Cthe_0561 139 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 125973690 Nonpathogen - hypothetical protein Cthe_1175 5 COG1723 COG1723, Uncharacterized conserved protein Function unknown 125973519 Common - uridylate kinase Cthe_1004 246 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 125974649 Common - Rubredoxin-type Fe(Cys)4 protein Cthe_2164 122 COG1773 COG1773, Rubredoxin Energy production and conversion 125973060 Common - peptidase M24 Cthe_0541 174 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 125973819 Common - PhoH-like protein Cthe_1304 198 COG1875 COG1875, Predicted ATPase related to phosphate starvation-inducible protein PhoH Signal transduction mechanisms 125972860 Common - histidine kinase Cthe_0339 59 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 125974885 Common - peptidase U57, YabG Cthe_2400 11 COG1162 COG1162, Predicted GTPases General function prediction only 125973153 Common - protein serine/threonine phosphatases Cthe_0635 130 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 125974989 Common - hypothetical protein Cthe_2504 20 COG3584 COG3584, Uncharacterized protein conserved in bacteria Function unknown 125975106 Common - Exopolysaccharide biosynthesis protein Cthe_2623 28 COG4632 EpsL, Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Carbohydrate transport and metabolism 125973316 Common - lipolytic enzyme, G-D-S-L Cthe_0798 6 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 125972997 Nonpathogen - hypothetical protein Cthe_0476 1 None None None 125973926 Common - tryptophan synthase subunit beta Cthe_1412 225 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 125973244 Common - putative aminopeptidase 1 Cthe_0726 44 COG1362 LAP4, Aspartyl aminopeptidase Amino acid transport and metabolism 125972530 Common - hypothetical protein Cthe_0005 2 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 125974054 Common - hypothetical protein Cthe_1544 2 None None None 125975698 Common - CRISPR-associated protein Cas4 Cthe_3220 23 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 125974596 Common - protein of unknown function DUF327 Cthe_2106 18 COG1728 COG1728, Uncharacterized protein conserved in bacteria Function unknown 125972805 Common - aldo/keto reductase Cthe_0283 204 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 125973289 Common - putative helix-turn-helix protein, YlxM/p13-like protein Cthe_0771 27 COG2739 COG2739, Uncharacterized protein conserved in bacteria Function unknown 125975560 Common - transglutaminase-like protein Cthe_3081 36 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 125975333 Nonpathogen - hypothetical protein Cthe_2851 1 None None None 125974556 Common - serine O-acetyltransferase Cthe_2066 206 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 125973908 Common - multi-sensor signal transduction histidine kinase Cthe_1393 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 125972790 Common - putative RNA polymerase sigma factor SigI Cthe_0268 14 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 125973891 Common - Homoserine dehydrogenase Cthe_1376 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 125972801 Nonpathogen - hypothetical protein Cthe_0279 2 None None None 125973810 Common - 5-formyltetrahydrofolate cyclo-ligase Cthe_1295 180 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 125974474 Common - Tetratricopeptide TPR_2 Cthe_1973 50 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 125974291 Common - glycoside hydrolase 15-related Cthe_1787 67 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 125974585 Common - hydrolase, TatD family Cthe_2095 240 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 125975266 Common - cobalamin B12-binding protein Cthe_2784 167 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 125973269 Common - transcriptional regulator, XRE family with cupin sensor Cthe_0751 125 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 125973987 Nonpathogen - hypothetical protein Cthe_1475 1 None None None 125974436 Common argS arginyl-tRNA synthetase Cthe_1935 248 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 125974863 Common - parB-like partition protein Cthe_2378 186 COG1475 Spo0J, Predicted transcriptional regulators Transcription 125973480 Common - dihydrodipicolinate reductase Cthe_0963 218 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 125974315 Common - transcriptional repressor, CopY family Cthe_1811 42 COG3682 COG3682, Predicted transcriptional regulator Transcription 125974589 Common - nucleoside recognition Cthe_2099 39 COG2715 SpmA, Uncharacterized membrane protein, required for spore maturation in B.subtilis. General function prediction only 125973524 Common - O-methyltransferase, family 3 Cthe_1009 108 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 125973661 Nonpathogen - hypothetical protein Cthe_1146 1 None None None 125973590 Common - protein of unknown function DUF881 Cthe_1075 25 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 125974758 Common - hypothetical protein Cthe_2273 21 COG3581 COG3581, Uncharacterized protein conserved in bacteria Function unknown 125973517 Nonpathogen - hypothetical protein Cthe_1002 1 None None None 125974125 Common - hypothetical protein Cthe_1618 49 COG5412 COG5412, Phage-related protein Function unknown 125974625 Common - glycoside hydrolase, family 43 Cthe_2138 28 COG3940 COG3940, Predicted beta-xylosidase General function prediction only 125974045 Common - hypothetical protein Cthe_1535 8 None None None 125972766 Common - heavy metal translocating P-type ATPase Cthe_0244 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 125973888 Common - YD repeat protein Cthe_1373 79 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 125974002 Common - transcriptional regulator, PadR-like family Cthe_1491 18 COG1695 COG1695, Predicted transcriptional regulators Transcription 125975010 Common - glutamyl-tRNA reductase Cthe_2525 177 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 125974918 Common - electron transport complex, RnfABCDGE type, E subunit Cthe_2433 76 COG4660 RnfE, Predicted NADH:ubiquinone oxidoreductase, subunit RnfE Energy production and conversion 125974789 Common - hypothetical protein Cthe_2304 7 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 125975185 Common - protein of unknown function DUF161 Cthe_2703 48 COG1284 COG1284, Uncharacterized conserved protein Function unknown 125972889 Common - NCAIR mutase (PurE)-related protein Cthe_0368 64 COG1691 COG1691, NCAIR mutase (PurE)-related proteins General function prediction only 125972724 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Cthe_0200 246 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 125973195 Common - phosphopentomutase Cthe_0677 72 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 125975204 Common - ribosomal protein L10 Cthe_2722 218 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 125974260 Common - Putative virion core protein (lumpy skin disease virus)-like protein Cthe_1756 52 COG4260 COG4260, Putative virion core protein (lumpy skin disease virus) Function unknown 125975177 Common - hypothetical protein Cthe_2695 3 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 125973131 Common - thiamine pyrophosphate enzyme-like TPP-binding Cthe_0613 95 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 125973372 Common - HAD superfamily (subfamily IIIA) phosphatase, TIGR01668 Cthe_0855 43 COG2179 COG2179, Predicted hydrolase of the HAD superfamily General function prediction only 125973704 Common - ABC transporter related protein Cthe_1189 249 COG4586 COG4586, ABC-type uncharacterized transport system, ATPase component General function prediction only 125975036 Common - Radical SAM Cthe_2552 68 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 125975249 Common - Methyltransferase type 12 Cthe_2767 17 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 125974952 Common - hypothetical protein Cthe_2467 72 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 125973254 Nonpathogen - cellulosome anchoring protein, cohesin region Cthe_0736 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 125974323 Common - ABC transporter related protein Cthe_1819 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 125972895 Common - glutamate dehydrogenase Cthe_0374 171 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 125973490 Common - stage V sporulation protein E Cthe_0975 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 125972612 Common - cell shape determining protein, MreB/Mrl family Cthe_0088 236 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 125975391 Common rplP 50S ribosomal protein L16 Cthe_2910 217 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 125973297 Common - copper amine oxidase-like protein Cthe_0779 71 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 125974349 Common - homoserine O-succinyltransferase Cthe_1845 64 COG1897 MetA, Homoserine trans-succinylase Amino acid transport and metabolism 125974052 Common - glutamyl-tRNA(Gln) amidotransferase, C subunit Cthe_1542 17 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 125974176 Common - Recombinase Cthe_1670 9 None None None 125973273 Common - aspartate aminotransferase Cthe_0755 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 125972598 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Cthe_0074 4 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 125973711 Common - hypothetical protein Cthe_1196 7 None None None 125974633 Common - glycoside hydrolase, family 5 Cthe_2147 20 COG2730 BglC, Endoglucanase Carbohydrate transport and metabolism 125973416 Nonpathogen - hypothetical protein Cthe_0899 1 None None None 125974995 Common - protein of unknown function DUF368 Cthe_2510 49 COG2035 COG2035, Predicted membrane protein Function unknown 125974377 Common - HMG-I and HMG-Y, DNA-binding Cthe_1873 47 None None None 125974171 Common - Hsp33 protein Cthe_1665 52 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 125975611 Common - alpha/beta hydrolase fold Cthe_3133 138 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 125974537 Common - conserved hypothetical protein precursor Cthe_2047 21 COG5281 COG5281, Phage-related minor tail protein Function unknown 125974400 Common - hypothetical protein Cthe_1897 3 None None None 125972586 Common - sulfatase Cthe_0062 82 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 125975638 Common - putative RNA methylase, NOL1/NOP2/sun family Cthe_3160 207 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 125972697 Nonpathogen - dehydrogenase (flavoproteins) Cthe_0173 10 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 125974425 Common - CTP synthetase Cthe_1923 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 125973868 Common - polysaccharide biosynthesis protein Cthe_1353 97 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 125973623 Nonpathogen - hypothetical protein Cthe_1108 1 None None None 125974197 Common - transposase IS3/IS911 Cthe_1692 39 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974256 Common - ABC transporter related protein Cthe_1752 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 125972870 Common - fructose-1,6-bisphosphate aldolase, class II Cthe_0349 179 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 125975164 Nonpathogen - hypothetical protein Cthe_2682 1 None None None 125972837 Common - PA14 Cthe_0316 32 COG3147 DedD, Uncharacterized protein conserved in bacteria Function unknown 125972927 Common - hypothetical protein Cthe_0406 26 None None None 125973079 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Cthe_0560 165 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 125973191 Common rnhA ribonuclease H Cthe_0673 177 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 125972958 Nonpathogen - hypothetical protein Cthe_0437 1 None None None 125972565 Nonpathogen - hypothetical protein Cthe_0041 2 None None None 125975008 Common - hypothetical protein Cthe_2523 21 None None None 125975449 Common - transcriptional regulator, GntR family Cthe_2969 138 COG1725 COG1725, Predicted transcriptional regulators Transcription 125973526 Common - Peptidoglycan glycosyltransferase Cthe_1011 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 125974440 Common - magnesium transporter Cthe_1939 173 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 125974023 Common - Type II site-specific deoxyribonuclease Cthe_1512 10 None None None 125973631 Common - HMG-I and HMG-Y, DNA-binding Cthe_1116 49 None None None 125972680 Common - Radical SAM Cthe_0156 65 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 125973232 Common - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase/S1 RNA-binding domain protein Cthe_0714 227 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 125972941 Common - dipicolinate synthase subunit A Cthe_0420 13 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 125973215 Nonpathogen - type IV pilus assembly PilZ Cthe_0697 1 None None None 125974027 Common - ribosome small subunit-dependent GTPase A Cthe_1516 163 COG1162 COG1162, Predicted GTPases General function prediction only 125972877 Common - transposase, mutator type Cthe_0356 89 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974456 Common - RNA binding S1 Cthe_1955 224 COG2183 Tex, Transcriptional accessory protein Transcription 125972672 Common - transposase, mutator type Cthe_0148 89 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 125975603 Common - heat shock protein Hsp20 Cthe_3125 133 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 125975695 Nonpathogen - hypothetical protein Cthe_3217 9 None None None 125972863 Common - hydrogenase, Fe-only Cthe_0342 184 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 125975677 Common - protein of unknown function UPF0118 Cthe_3199 206 COG0628 PerM, Predicted permease General function prediction only 125973090 Common - sun protein Cthe_0571 214 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 125974850 Common - tRNA modification GTPase TrmE Cthe_2365 224 COG0486 ThdF, Predicted GTPase General function prediction only 125974568 Common - protein of unknown function UPF0029 Cthe_2078 136 COG1739 COG1739, Uncharacterized conserved protein Function unknown 125972976 Common - Mg chelatase, subunit ChlI Cthe_0455 197 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 125974520 Nonpathogen - hypothetical protein Cthe_2026 1 None None None 125974154 Common - hypothetical protein Cthe_1648 15 None None None 125972990 Nonpathogen - flagellar export protein FliJ Cthe_0469 3 COG2882 FliJ, Flagellar biosynthesis chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 125973399 Common - protein of unknown function DUF6, transmembrane Cthe_0882 121 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 125972560 Common - hydroxylamine reductase Cthe_0036 75 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 125973358 Common - hypothetical protein Cthe_0840 11 None None None 125975461 Common - hypothetical protein Cthe_2981 5 None None None 125973575 Common - AIR synthase related protein-like protein Cthe_1060 182 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 125974949 Common - hypothetical protein Cthe_2464 5 None None None 125974285 Nonpathogen - hypothetical protein Cthe_1781 1 None None None 125972636 Common - UDP-N-acetylenolpyruvoylglucosamine reductase Cthe_0112 211 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 125974976 Common - hypothetical protein Cthe_2491 5 None None None 125974962 Nonpathogen - hypothetical protein Cthe_2477 1 None None None 125974682 Common - Carbohydrate binding family 6 Cthe_2197 78 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 125974190 Common - ABC transporter related protein Cthe_1685 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 125975599 Common - hypothetical protein Cthe_3121 4 None None None 125974148 Nonpathogen - hypothetical protein Cthe_1642 1 None None None 125974823 Common - glycosyl transferase, group 1 Cthe_2338 32 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 125973146 Common - hypothetical protein Cthe_0628 7 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 125975629 Common cobU adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase Cthe_3151 129 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 125975498 Common - 4Fe-4S ferredoxin, iron-sulfur binding Cthe_3019 186 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 125975303 Common - response regulator receiver modulated CheB methylesterase Cthe_2821 217 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 125973440 Common - hypothetical protein Cthe_0923 5 None None None 125975146 Common - ABC-1 Cthe_2664 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 125974506 Common - conserved hypothetical protein precursor Cthe_2009 3 None None None 125975397 Common - ribosomal protein S14 Cthe_2916 206 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 125972784 Common - gamma-glutamyl phosphate reductase Cthe_0262 193 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 125975196 Common - acetolactate synthase, large subunit, biosynthetic type Cthe_2714 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 125972938 Common rpsO 30S ribosomal protein S15 Cthe_0417 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 125975272 Common - ABC transporter related protein Cthe_2790 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 125975116 Common - transcriptional regulator, AraC family Cthe_2634 156 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 125973097 Common - glycoside hydrolase, family 9 Cthe_0578 16 None None None 125974493 Common - Integrase, catalytic region Cthe_1993 153 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974368 Common - acetylglutamate kinase Cthe_1864 219 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 125974061 Nonpathogen - MAEBL, putative Cthe_1552 1 None None None 125975521 Common - hypothetical protein Cthe_3042 16 COG5291 COG5291, Predicted membrane protein Function unknown 125974217 Common - phage major tail protein, phi13 family Cthe_1713 10 None None None 125972983 Common - flagellar basal-body rod protein FlgB Cthe_0462 61 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 125974031 Nonpathogen - hypothetical protein Cthe_1520 1 None None None 125974678 Common - Carbohydrate binding family 6 Cthe_2193 25 COG3401 COG3401, Fibronectin type 3 domain-containing protein General function prediction only 125972778 Common - histidine kinase Cthe_0256 205 COG1609 PurR, Transcriptional regulators Transcription 125975665 Common - putative anti-sigma regulatory factor, serine/threonine protein kinase Cthe_3187 9 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 125972651 Common - RNA methyltransferase, TrmH family, group 2 Cthe_0127 171 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 125973706 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Cthe_1191 67 COG0546 Gph, Predicted phosphatases General function prediction only 125973615 Nonpathogen - prepilin-type cleavage/methylation Cthe_1100 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 125974986 Nonpathogen - hypothetical protein Cthe_2501 1 None None None 125972591 Common - NAD-dependent deacetylase Cthe_0067 151 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 125974514 Common - conserved hypothetical protein precursor Cthe_2019 20 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 125973454 Common - fatty acid/phospholipid synthesis protein PlsX Cthe_0937 178 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 125975620 Common - hypothetical protein Cthe_3142 4 None None None 125973012 Common - CheW protein Cthe_0491 129 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 125973027 Common - Exonuclease, RNase T and DNA polymerase III Cthe_0507 29 COG5018 KapD, Inhibitor of the KinA pathway to sporulation, predicted exonuclease General function prediction only 125972851 Common - hypothetical protein Cthe_0330 12 None None None 125974279 Common - peptidase M22, glycoprotease Cthe_1775 187 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 125974713 Common - MaoC-like dehydratase Cthe_2228 30 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 125975503 Common - NADH dehydrogenase (quinone) Cthe_3024 206 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 125973046 Nonpathogen - hypothetical protein Cthe_0526 1 None None None 125975091 Common - F0F1 ATP synthase subunit beta Cthe_2608 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 125973006 Common - flagellar biosynthesis protein FlhA Cthe_0485 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 125973805 Nonpathogen - hypothetical protein Cthe_1290 1 None None None 125973265 Common - extracellular solute-binding protein, family 1 Cthe_0747 137 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 125974829 Common - Undecaprenyl-phosphate galactose phosphotransferase Cthe_2344 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 125975499 Common - NADH dehydrogenase (ubiquinone) Cthe_3020 199 COG3261 HycE, Ni,Fe-hydrogenase III large subunit Energy production and conversion 125975317 Nonpathogen - hypothetical protein Cthe_2835 1 None None None 125974836 Common - hypothetical protein Cthe_2351 1 None None None 125973872 Common - glycosyl transferase, group 1 Cthe_1357 224 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 125972660 Nonpathogen - 4'-phosphopantetheinyl transferase Cthe_0136 7 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 125973353 Nonpathogen - hypothetical protein Cthe_0835 7 COG5547 COG5547, Small integral membrane protein Function unknown 125974344 Common - cysteine synthase A Cthe_1840 219 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 125973002 Common fliP flagellar biosynthesis protein FliP Cthe_0481 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 125975424 Common - ABC-2 type transporter Cthe_2943 70 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 125974047 Common - hypothetical protein Cthe_1537 7 None None None 125975434 Nonpathogen - hypothetical protein Cthe_2953 4 None None None 125972547 Common - 8-amino-7-oxononanoate synthase Cthe_0022 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 125975530 Common - transposase, mutator type Cthe_3051 89 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 125975240 Common - hypothetical protein Cthe_2758 4 None None None 125974887 Common - Peptidoglycan-binding LysM Cthe_2402 9 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 125975298 Common - transposase, mutator type Cthe_2816 88 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973467 Common - carbamoyl-phosphate synthase, small subunit Cthe_0950 235 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 125975539 Nonpathogen - hypothetical protein Cthe_3060 1 None None None 125975378 Common - transcription elongation factor GreA Cthe_2897 204 COG0782 GreA, Transcription elongation factor Transcription 125975582 Common - putative CoA-substrate-specific enzyme activase Cthe_3104 65 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 125975121 Common - acylneuraminate cytidylyltransferase Cthe_2639 72 COG1083 NeuA, CMP-N-acetylneuraminic acid synthetase Cell envelope biogenesis, outer membrane 125974016 Common - S-layer-like domain containing protein Cthe_1505 24 None None None 125974004 Common - transcriptional regulator, PadR-like family Cthe_1493 43 COG1695 COG1695, Predicted transcriptional regulators Transcription 125974201 Common - hypothetical protein Cthe_1696 13 COG5658 COG5658, Predicted integral membrane protein Function unknown 125975229 Common - PHP-like protein Cthe_2747 142 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 125973675 Common - S23 ribosomal protein Cthe_1160 26 None None None 125973102 Common - response regulator receiver protein Cthe_0583 226 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 125972738 Common - phenylalanyl-tRNA synthetase, alpha subunit Cthe_0214 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 125972922 Common - methyl-accepting chemotaxis sensory transducer Cthe_0401 171 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 125973965 Common - KWG repeat containing protein Cthe_1452 28 None None None 125974608 Common - ABC transporter related protein Cthe_2118 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 125973496 Common - S-adenosyl-methyltransferase MraW Cthe_0981 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 125973843 Common - Stage II sporulation P Cthe_1328 15 None None None 125972668 Common - preprotein translocase, SecG subunit Cthe_0144 15 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 125974869 Common - S-layer-like domain containing protein Cthe_2384 19 None None None 125975366 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase Cthe_2885 210 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 125975400 Common - ribosomal protein L18 Cthe_2919 216 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 125972687 Common - GTP1/OBG subdomain containing protein Cthe_0163 249 COG0536 Obg, Predicted GTPase General function prediction only 125974878 Common - thiamine pyrophosphate enzyme-like TPP-binding Cthe_2393 122 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 125972731 Common - hypothetical protein Cthe_0207 10 None None None 125972747 Common - hypothetical protein Cthe_0223 4 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 125972913 Common - inner-membrane translocator Cthe_0392 114 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 125972977 Common - protein of unknown function UPF0047 Cthe_0456 114 COG0432 COG0432, Uncharacterized conserved protein Function unknown 125974267 Common - ABC transporter related protein Cthe_1763 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 125973790 Common - H+-ATPase subunit H Cthe_1275 26 None None None 125974705 Common - NAD-dependent epimerase/dehydratase Cthe_2220 234 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 125975048 Common - hypothetical protein Cthe_2564 4 None None None 125972601 Common - hypothetical protein Cthe_0077 2 None None None 125973686 Common - Serine-type D-Ala-D-Ala carboxypeptidase Cthe_1171 153 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 125974000 Common - methyl-accepting chemotaxis sensory transducer Cthe_1488 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 125974555 Common - cysteinyl-tRNA synthetase Cthe_2065 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 125974356 Common - Hsp33 protein Cthe_1852 122 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 125974046 Common - ABC transporter related protein Cthe_1536 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 125974690 Common - cyanophycinase Cthe_2205 33 COG4242 CphB, Cyanophycinase and related exopeptidases Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism 125975120 Common - O-antigen polymerase Cthe_2638 44 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 125974018 Common - protein of unknown function UPF0131 Cthe_1507 21 COG2105 COG2105, Uncharacterized conserved protein Function unknown 125972871 Common - signal peptidase I Cthe_0350 206 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 125975372 Common groES co-chaperonin GroES Cthe_2891 212 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 125972648 Common - SpoVA protein Cthe_0124 15 None None None 125972975 Common - hypothetical protein Cthe_0454 2 None None None 125973784 Common - hypothetical protein Cthe_1269 11 COG2006 COG2006, Uncharacterized conserved protein Function unknown 125974637 Nonpathogen - hypothetical protein Cthe_2151 2 None None None 125972638 Common - hypothetical protein Cthe_0114 102 COG0391 COG0391, Uncharacterized conserved protein Function unknown 125974712 Common - phosphopantetheine-binding Cthe_2227 23 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 125975492 Common - hydrogenase expression/formation protein HypE Cthe_3013 139 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 125974112 Common - phosphate ABC transporter, inner membrane subunit PstA Cthe_1603 234 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 125975586 Common - phage SPO1 DNA polymerase-related protein Cthe_3108 153 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 125973267 Common - binding-protein-dependent transport systems inner membrane component Cthe_0749 211 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 125975023 Nonpathogen - thiamine biosynthesis protein ThiS Cthe_2538 6 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 125973047 Nonpathogen - hypothetical protein Cthe_0527 1 None None None 125972665 Common - Integrase, catalytic region Cthe_0141 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 125974927 Common - carbohydrate kinase, FGGY Cthe_2442 177 COG0554 GlpK, Glycerol kinase Energy production and conversion 125972982 Common - gid protein Cthe_0461 189 COG1206 Gid, NAD(FAD)-utilizing enzyme possibly involved in translation Translation, ribosomal structure and biogenesis 125975619 Common - lipolytic enzyme, G-D-S-L Cthe_3141 17 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 125974144 Common - ParB-like nuclease Cthe_1638 93 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 125975381 Common - RNA polymerase, sigma 28 subunit Cthe_2900 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 125974822 Nonpathogen - hypothetical protein Cthe_2337 1 None None None 125972972 Common - protein of unknown function DUF115 Cthe_0451 20 COG2604 COG2604, Uncharacterized protein conserved in bacteria Function unknown 125972590 Common - hypothetical protein Cthe_0066 1 None None None 125973164 Common - anaerobic ribonucleoside triphosphate reductase Cthe_0646 131 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 125974346 Common - O-acetylhomoserine/O-acetylserine sulfhydrylase Cthe_1842 207 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 125974858 Common - RNA-binding S4 Cthe_2373 54 COG2501 COG2501, Uncharacterized conserved protein Function unknown 125973877 Common - NusG antitermination factor Cthe_1362 81 COG0250 NusG, Transcription antiterminator Transcription 125973024 Common - Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation)-like protein Cthe_0504 82 COG2843 PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) Cell envelope biogenesis, outer membrane 125974631 Common - DNA polymerase III subunits gamma and tau Cthe_2144 247 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 125974799 Nonpathogen - hypothetical protein Cthe_2314 1 None None None 125974123 Common - phage minor structural protein Cthe_1616 8 COG4926 PblB, Phage-related protein Function unknown 125972740 Common - small acid-soluble spore protein, alpha/beta type Cthe_0216 6 None None None 125972957 Common - Tetratricopeptide TPR_2 Cthe_0436 167 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 125973487 Nonpathogen - hypothetical protein Cthe_0972 1 None None None 125974641 Common - S-layer-like domain containing protein Cthe_2155 26 None None None 125973253 Nonpathogen - cellulosome anchoring protein, cohesin region Cthe_0735 1 None None None 125975316 Common - conserved hypothetical protein precursor Cthe_2834 17 COG5281 COG5281, Phage-related minor tail protein Function unknown 125975197 Common - Integrase, catalytic region Cthe_2715 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 125974299 Common - phospho-2-dehydro-3-deoxyheptonate aldolase Cthe_1795 177 COG2876 AroA, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 125972717 Common - sodium/hydrogen exchanger Cthe_0193 12 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 125975193 Nonpathogen - hypothetical protein Cthe_2711 2 None None None 125974037 Common - ABC transporter related protein Cthe_1526 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 125975626 Common - ABC transporter related protein Cthe_3148 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 125975000 Common - Guanine deaminase Cthe_2515 212 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 125974906 Nonpathogen - hypothetical protein Cthe_2421 1 None None None 125974987 Common - CMP/dCMP deaminase, zinc-binding Cthe_2502 219 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 125975627 Common - aminoacyl-histidine dipeptidase Cthe_3149 58 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 125973149 Nonpathogen - hypothetical protein Cthe_0631 1 None None None 125975306 Common - hypothetical protein Cthe_2824 17 None None None 125974367 Common - N-acetyl-gamma-glutamyl-phosphate reductase Cthe_1863 222 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 125973462 Common - metallophosphoesterase Cthe_0945 6 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 125975428 Common - prolyl-tRNA synthetase Cthe_2947 247 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 125973331 Common - peptidase S55, SpoIVB Cthe_0813 19 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 125975285 Common - binding-protein-dependent transport systems inner membrane component Cthe_2803 204 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 125973921 Common - hypothetical protein Cthe_1407 11 None None None 125972849 Common - peptide chain release factor 3 Cthe_0328 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 125972597 Common - hypothetical protein Cthe_0073 4 None None None 125975327 Nonpathogen - hypothetical protein Cthe_2845 1 None None None 125973793 Common - ATP-dependent DNA helicase RecG Cthe_1278 214 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 125974856 Common dnaA chromosomal replication initiation protein Cthe_2371 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 125973127 Common - peptidase M42 Cthe_0609 87 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 125972789 Common - type 3a, cellulose-binding Cthe_0267 27 COG3889 COG3889, Predicted solute binding protein General function prediction only 125973135 Common - recombination factor protein RarA Cthe_0617 245 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 125975252 Common - transposase IS116/IS110/IS902 Cthe_2770 95 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974663 Nonpathogen - hypothetical protein Cthe_2178 1 None None None 125972542 Common - protein of unknown function DUF1538 Cthe_0017 23 None None None 125975642 Common - two component transcriptional regulator, AraC family Cthe_3164 148 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 125974580 Common - hypothetical protein Cthe_2090 4 None None None 125974513 Common - hypothetical protein Cthe_2018 6 None None None 125972657 Common - AMP-dependent synthetase and ligase Cthe_0133 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 125972928 Common - Radical SAM Cthe_0407 55 COG4277 COG4277, Predicted DNA-binding protein with the Helix-hairpin-helix motif General function prediction only 125973040 Common - hypothetical protein Cthe_0520 22 None None None 125974849 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA Cthe_2364 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 125974701 Nonpathogen - hypothetical protein Cthe_2216 4 None None None 125973803 Common - two component transcriptional regulator, winged helix family Cthe_1288 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 125972780 Common - cellulosome enzyme, dockerin type I Cthe_0258 41 COG5184 ATS1, Alpha-tubulin suppressor and related RCC1 domain-containing proteins Cell division and chromosome partitioning / Cytoskeleton 125974679 Common - Carbohydrate binding family 6 Cthe_2194 62 COG2382 Fes, Enterochelin esterase and related enzymes Inorganic ion transport and metabolism 125975688 Common - protein of unknown function DUF324 Cthe_3210 7 COG1337 COG1337, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 125975594 Common - mannose-6-phosphate isomerase, class I Cthe_3116 51 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 125973707 Common - hypothetical protein Cthe_1192 2 None None None 125974009 Common - methyl-accepting chemotaxis sensory transducer Cthe_1498 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 125974078 Common - O-acetylhomoserine aminocarboxypropyltransferase Cthe_1569 208 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 125975360 Common - cellulosome enzyme, dockerin type I Cthe_2879 6 None None None 125974292 Common - glycosyl transferase, family 2 Cthe_1788 116 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 125973459 Common - MiaB-like tRNA modifying enzyme YliG Cthe_0942 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 125973058 Common - ABC transporter related protein Cthe_0539 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 125973277 Common - flagellar biosynthesis Cthe_0759 10 COG2257 COG2257, Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB Function unknown 125974879 Nonpathogen - hypothetical protein Cthe_2394 1 None None None 125972633 Nonpathogen - cellulosome enzyme, dockerin type I Cthe_0109 1 None None None 125972605 Common - arginine biosynthesis bifunctional protein ArgJ Cthe_0081 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 125975500 Nonpathogen - Ech hydrogenase, subunit EchD, putative Cthe_3021 8 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 125973637 Nonpathogen - hypothetical protein Cthe_1122 1 None None None 125973729 Common - hypothetical protein Cthe_1214 13 COG0730 COG0730, Predicted permeases General function prediction only 125975158 Common - GumN Cthe_2676 50 COG3735 COG3735, Uncharacterized protein conserved in bacteria Function unknown 125974865 Common - TPR repeat domain containing protein Cthe_2380 2 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 125972734 Common - transcriptional regulator, LacI family Cthe_0210 128 COG1609 PurR, Transcriptional regulators Transcription 125974569 Common - signal peptidase I Cthe_2079 162 COG4959 TraF, Type IV secretory pathway, protease TraF Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 125975531 Common - YD repeat protein Cthe_3052 90 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 125975483 Common - ferredoxin Cthe_3004 229 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 125972894 Common - ferredoxin--NADP(+) reductase subunit alpha Cthe_0373 84 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 125973561 Common - extracellular solute-binding protein, family 1 Cthe_1046 47 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 125975053 Nonpathogen - hypothetical protein Cthe_2569 1 None None None 125973628 Common - SEC-C motif containing protein Cthe_1113 5 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 125973376 Nonpathogen - hypothetical protein Cthe_0859 1 None None None 125972652 Common - Integrase, catalytic region Cthe_0128 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 125973724 Nonpathogen - hypothetical protein Cthe_1209 1 None None None 125975228 Nonpathogen - protein of unknown function DUF402 Cthe_2746 4 COG2306 COG2306, Uncharacterized conserved protein Function unknown 125975365 Common - Imidazoleglycerol-phosphate dehydratase Cthe_2884 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 125974571 Common - small GTP-binding protein Cthe_2081 238 COG2262 HflX, GTPases General function prediction only 125972621 Common - peptidase M23B Cthe_0097 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 125975080 Common - sugar-phosphate isomerases, RpiB/LacA/LacB family Cthe_2597 129 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 125975404 Common - preprotein translocase, SecY subunit Cthe_2923 231 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 125974462 Common - Nucleotidyl transferase Cthe_1961 242 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 125975331 Nonpathogen - hypothetical protein Cthe_2849 1 None None None 125975463 Common - methyl-accepting chemotaxis sensory transducer Cthe_2983 146 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 125973473 Nonpathogen - hypothetical protein Cthe_0956 4 None None None 125973588 Common - protein of unknown function DUF1429 Cthe_1073 15 None None None 125974396 Nonpathogen - hypothetical protein Cthe_1893 3 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 125973773 Nonpathogen - copper amine oxidase-like protein Cthe_1258 9 None None None 125974483 Nonpathogen - hypothetical protein Cthe_1982 1 None None None 125974392 Nonpathogen - hypothetical protein Cthe_1888 2 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 125975086 Common - ATP synthase F0, C subunit Cthe_2603 60 None None None 125975208 Common - ribosomal protein L7Ae/L30e/S12e/Gadd45 Cthe_2726 37 COG1358 RPL8A, Ribosomal protein HS6-type (S12/L30/L7a) Translation, ribosomal structure and biogenesis 125972563 Common - methyl-accepting chemotaxis sensory transducer Cthe_0039 161 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 125972554 Nonpathogen - phosphatidate cytidylyltransferase Cthe_0030 4 COG0170 SEC59, Dolichol kinase Lipid metabolism 125975019 Common - sulfate ABC transporter, ATPase subunit Cthe_2534 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 125973620 Common - type II secretion system protein Cthe_1105 146 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 125975602 Common - AMP-dependent synthetase and ligase Cthe_3124 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 125973392 Common - anthranilate synthase component I Cthe_0875 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 125974575 Common - deoxyuridine 5'-triphosphate nucleotidohydrolase Dut Cthe_2085 168 COG0756 Dut, dUTPase Nucleotide transport and metabolism 125973746 Common - Serine-type D-Ala-D-Ala carboxypeptidase Cthe_1231 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 125975668 Common - helicase, RecD/TraA family Cthe_3190 144 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 125974271 Common - hypothetical protein Cthe_1767 6 None None None 125974727 Common flgL flagellar hook-associated protein FlgL Cthe_2242 102 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 125975179 Common alr alanine racemase Cthe_2697 201 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 125973219 Common - oxaloacetate decarboxylase Cthe_0701 171 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 125975145 Common - methyl-accepting chemotaxis sensory transducer Cthe_2663 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 125974472 Nonpathogen - hypothetical protein Cthe_1971 1 COG5444 COG5444, Uncharacterized conserved protein Function unknown 125972764 Common - hypothetical protein Cthe_0242 24 COG4866 COG4866, Uncharacterized conserved protein Function unknown 125975165 Nonpathogen - hypothetical protein Cthe_2683 1 None None None 125973450 Common - acyl carrier protein Cthe_0933 211 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 125973966 Common - hypothetical protein Cthe_1454 4 None None None 125974627 Nonpathogen - hypothetical protein Cthe_2140 2 None None None 125972749 Common - hypothetical protein Cthe_0227 3 None None None 125975653 Common - protein of unknown function DUF421 Cthe_3175 71 COG2323 COG2323, Predicted membrane protein Function unknown 125974479 Nonpathogen - hypothetical protein Cthe_1978 1 None None None 125973031 Common - histidine kinase Cthe_0511 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 125972566 Common - small GTP-binding protein Cthe_0042 222 COG1160 COG1160, Predicted GTPases General function prediction only 125972952 Common - hypothetical protein Cthe_0431 7 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 125972869 Common - Integrase, catalytic region Cthe_0348 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 125975460 Common - hypothetical protein Cthe_2980 4 None None None 125975417 Common - ABC transporter related protein Cthe_2936 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 125975009 Common - transcriptional regulator, BadM/Rrf2 family Cthe_2524 173 COG1959 COG1959, Predicted transcriptional regulator Transcription 125972779 Common - twitching motility protein Cthe_0257 176 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 125972582 Common - putative RNA polymerase sigma factor SigI Cthe_0058 14 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 125973041 Common - helicase-like protein Cthe_0521 100 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 125974444 Common - deoxyribose-phosphate aldolase Cthe_1943 138 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 125972884 Common - aminotransferase, class I and II Cthe_0363 241 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 125975156 Common - hypothetical protein Cthe_2674 2 None None None 125974790 Common - undecaprenyl pyrophosphate phosphatase Cthe_2305 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 125973404 Nonpathogen - hypothetical protein Cthe_0887 1 None None None 125974454 Common - cell wall hydrolase, SleB Cthe_1953 58 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 125974374 Nonpathogen - GCN5-related N-acetyltransferase Cthe_1870 8 COG3153 COG3153, Predicted acetyltransferase General function prediction only 125972721 Common - glutamine amidotransferase, class-II Cthe_0197 84 COG0067 GltB, Glutamate synthase domain 1 Amino acid transport and metabolism 125973742 Common - Thymidylate synthase Cthe_1227 136 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 125974699 Common - hypothetical protein Cthe_2214 97 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 125973274 Common - Membrane dipeptidase Cthe_0756 104 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 125973820 Common - Cupin 2, conserved barrel Cthe_1305 18 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 125973196 Common - pyrimidine-nucleoside phosphorylase Cthe_0678 125 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 125973075 Common - asparagine synthase (glutamine-hydrolyzing) Cthe_0556 158 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 125973718 Common - SpoVR Cthe_1203 71 COG2719 SpoVR, Uncharacterized conserved protein Function unknown 125975099 Common - SpoIID/LytB domain containing protein Cthe_2616 46 COG2385 SpoIID, Sporulation protein and related proteins Cell division and chromosome partitioning 125973716 Common - purine nucleoside phosphorylase I, inosine and guanosine-specific Cthe_1201 154 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 125974779 Common - transposase Cthe_2294 84 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974780 Common - IstB-like ATP-binding protein Cthe_2295 98 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 125973839 Common - heat-inducible transcription repressor HrcA Cthe_1324 151 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 125972607 Common - serine phosphatase Cthe_0083 110 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 125973396 Common - Integrase, catalytic region Cthe_0879 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 125975201 Common - NusG antitermination factor Cthe_2719 215 COG0250 NusG, Transcription antiterminator Transcription 125974178 Nonpathogen - hypothetical protein Cthe_1672 1 None None None 125973789 Common - nucleoside recognition Cthe_1274 17 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 125974959 Common - phage terminase, large subunit, PBSX family Cthe_2474 16 COG1783 XtmB, Phage terminase large subunit General function prediction only 125974982 Nonpathogen - hypothetical protein Cthe_2497 1 None None None 125972881 Common - thioredoxin Cthe_0360 235 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 125973973 Common - FAD dependent oxidoreductase Cthe_1461 97 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 125972906 Nonpathogen - hypothetical protein Cthe_0385 1 None None None 125973653 Common - protein of unknown function DUF87 Cthe_1138 91 COG0433 COG0433, Predicted ATPase General function prediction only 125973014 Common - CheD, stimulates methylation of MCP proteins Cthe_0493 87 COG1871 CheD, Chemotaxis protein; stimulates methylation of MCP proteins Cell motility and secretion / Signal transduction mechanisms 125973295 Common - DNA mismatch repair protein MutS Cthe_0777 208 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 125974237 Nonpathogen - hypothetical protein Cthe_1733 1 None None None 125975030 Common - signal transduction histidine kinase regulating citrate/malate metabolism Cthe_2545 19 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 125972614 Common - hypothetical protein Cthe_0090 12 COG2891 MreD, Cell shape-determining protein Cell envelope biogenesis, outer membrane 125974772 Common - transcriptional regulator, AraC family Cthe_2287 133 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 125974685 Common - hypothetical protein Cthe_2200 8 None None None 125973324 Common - PAS/PAC sensor hybrid histidine kinase Cthe_0806 226 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 125973210 Common - Integrase, catalytic region Cthe_0692 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 125975410 Common rpsM 30S ribosomal protein S13 Cthe_2929 248 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 125972684 Common rplU 50S ribosomal protein L21 Cthe_0160 199 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 125973597 Nonpathogen - hypothetical protein Cthe_1082 1 None None None 125975377 Nonpathogen - hypothetical protein Cthe_2896 2 None None None 125974011 Common - ABC transporter related protein Cthe_1500 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 125973362 Common - stage III sporulation protein spoIIIAB Cthe_0844 14 None None None 125974725 Common - flagellar assembly protein FliW Cthe_2240 42 COG1699 COG1699, Uncharacterized protein conserved in bacteria Function unknown 125973829 Common - DNA-directed RNA polymerase, omega subunit Cthe_1314 28 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 125973831 Common - hypothetical protein Cthe_1316 33 COG2052 COG2052, Uncharacterized protein conserved in bacteria Function unknown 125975515 Common - methyl-accepting chemotaxis sensory transducer Cthe_3036 173 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 125974332 Nonpathogen - hypothetical protein Cthe_1828 1 None None None 125974525 Common - transposase IS200-like protein Cthe_2031 73 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974257 Common - transport system permease protein Cthe_1753 186 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 125975170 Common - polysaccharide biosynthesis protein Cthe_2688 33 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 125972728 Common - protein of unknown function DUF1294 Cthe_0204 43 COG3326 COG3326, Predicted membrane protein Function unknown 125974586 Common - methionyl-tRNA synthetase Cthe_2096 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 125975251 Common - protein of unknown function DUF542, ScdA-like protein Cthe_2769 46 COG2846 COG2846, Regulator of cell morphogenesis and NO signaling Cell division and chromosome partitioning 125975264 Common - N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD Cthe_2782 17 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 125973600 Common - glycosyl transferase, group 1 Cthe_1085 208 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 125973914 Common - glycosyl hydrolase 53 Cthe_1400 20 COG3867 COG3867, Arabinogalactan endo-1,4-beta-galactosidase Carbohydrate transport and metabolism 125973163 Common - homocysteine S-methyltransferase Cthe_0645 186 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 125974250 Common - hypothetical protein Cthe_1746 7 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 125973660 Common - N-6 DNA methylase Cthe_1145 66 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 125975104 Common - protein of unknown function DUF1078-like protein Cthe_2621 125 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 125973516 Common - undecaprenyl diphosphate synthase Cthe_1001 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 125973988 Nonpathogen - hypothetical protein Cthe_1476 1 None None None 125973038 Common - type III restriction enzyme, res subunit Cthe_0518 41 COG3587 COG3587, Restriction endonuclease Defense mechanisms 125974236 Common - hypothetical protein Cthe_1732 4 None None None 125973471 Common - Uracil phosphoribosyltransferase Cthe_0954 114 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 125975596 Common - hemerythrin-like metal-binding protein Cthe_3118 46 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 125975459 Common - 4Fe-4S ferredoxin, iron-sulfur binding Cthe_2979 74 COG2768 COG2768, Uncharacterized Fe-S center protein General function prediction only 125972716 Common - Integrase, catalytic region Cthe_0192 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 125974913 Common - modification methylase, HemK family Cthe_2428 228 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 125974777 Nonpathogen - hypothetical protein Cthe_2292 1 None None None 125973559 Nonpathogen - hypothetical protein Cthe_1044 1 None None None 125975101 Common - stage III sporulation protein D, SpoIIID Cthe_2618 15 None None None 125972791 Common - glycoside hydrolase, family 8 Cthe_0269 22 COG3405 CelA, Endoglucanase Y Carbohydrate transport and metabolism 125974353 Common - Heavy metal transport/detoxification protein Cthe_1849 82 COG2836 COG2836, Uncharacterized conserved protein Function unknown 125974910 Common - MotA/TolQ/ExbB proton channel Cthe_2425 115 COG1291 MotA, Flagellar motor component Cell motility and secretion 125973850 Common - peptidase A24A, prepilin type IV Cthe_1335 45 COG4960 CpaA, Flp pilus assembly protein, protease CpaA Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 125975097 Common - hypothetical protein Cthe_2614 7 None None None 125973341 Common - hypothetical protein Cthe_0823 66 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974867 Common - major facilitator superfamily MFS_1 Cthe_2382 150 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 125974244 Common - BRO-like protein Cthe_1740 36 COG3617 COG3617, Prophage antirepressor Transcription 125973797 Common - diguanylate cyclase with GAF sensor Cthe_1282 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 125972994 Common - flagellar operon protein Cthe_0473 16 None None None 125972646 Common - SpoVA protein Cthe_0122 15 None None None 125973947 Common - short-chain dehydrogenase/reductase SDR Cthe_1433 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 125974736 Common - Methionine adenosyltransferase Cthe_2251 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 125974770 Common - CheW protein Cthe_2285 136 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 125974280 Common - protein of unknown function UPF0079 Cthe_1776 209 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 125972571 Common - copper amine oxidase-like protein Cthe_0047 10 None None None 125973975 Nonpathogen - protein of unknown function DUF891 Cthe_1463 2 COG4679 COG4679, Phage-related protein Function unknown 125975016 Common - sulfate ABC transporter, periplasmic sulfate-binding protein Cthe_2531 103 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 125972733 Common - glycosyltransferase Cthe_0209 162 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 125974403 Common - transposase, mutator type Cthe_1901 89 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 125972578 Common - protein of unknown function DUF187 Cthe_0054 50 COG1649 COG1649, Uncharacterized protein conserved in bacteria Function unknown 125972808 Common - response regulator receiver sensor signal transduction histidine kinase Cthe_0286 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 125973905 Common - alpha/beta hydrolase fold Cthe_1390 79 COG2267 PldB, Lysophospholipase Lipid metabolism 125973768 Common - phosphoenolpyruvate synthase Cthe_1253 26 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 125973566 Common - integral membrane protein MviN Cthe_1051 214 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 125973677 Common - D-fructose-6-phosphate amidotransferase Cthe_1162 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 125974468 Common - DNA segregation ATPase FtsK/SpoIIIE and related proteins Cthe_1967 18 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 125974039 Common - two component transcriptional regulator, winged helix family Cthe_1528 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 125973898 Common - Tetratricopeptide TPR_2 Cthe_1383 6 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 125975634 Common - methyl-accepting chemotaxis sensory transducer Cthe_3156 131 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 125974434 Common - Zn-dependent hydrolase of the beta-lactamase fold Cthe_1933 89 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 125975225 Common - putative metalloendopeptidase, glycoprotease family Cthe_2743 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 125973249 Common - Shikimate kinase Cthe_0731 198 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 125973092 Common - protein serine/threonine phosphatases Cthe_0573 138 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 125975231 Common - hypothetical protein Cthe_2749 68 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973025 Common - formate acetyltransferase Cthe_0505 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 125972754 Nonpathogen - hypothetical protein Cthe_0232 1 None None None 125973548 Common gatC aspartyl/glutamyl-tRNA amidotransferase subunit C Cthe_1033 90 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 125975324 Common - hypothetical protein Cthe_2842 3 None None None 125974895 Common - protein of unknown function DUF342 Cthe_2410 39 COG1315 COG1315, Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain DNA replication, recombination, and repair 125973518 Common - ribosome recycling factor Cthe_1003 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 125974022 Common - DNA methylase N-4/N-6 Cthe_1511 51 COG1041 COG1041, Predicted DNA modification methylase DNA replication, recombination, and repair 125973114 Common - GTP-binding protein Cthe_0596 192 COG0218 COG0218, Predicted GTPase General function prediction only 125974756 Nonpathogen - cellulosome enzyme, dockerin type I Cthe_2271 1 None None None 125974970 Common - hypothetical protein Cthe_2485 6 None None None 125973144 Common - hypothetical protein Cthe_0626 2 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 125974703 Common - flagellar hook-associated 2-like protein Cthe_2218 92 COG1345 FliD, Flagellar capping protein Cell motility and secretion 125974096 Common - ABC transporter related protein Cthe_1587 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 125973641 Nonpathogen - hypothetical protein Cthe_1126 1 None None None 125975045 Common - CDP-glucose 4,6-dehydratase Cthe_2561 232 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 125973242 Common - histidinol phosphate phosphatase HisJ family Cthe_0724 39 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 125973122 Nonpathogen - hypothetical protein Cthe_0604 1 None None None 125974745 Common - Prephenate dehydratase Cthe_2260 214 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 125974977 Common - Baseplate J-like protein Cthe_2492 14 COG3299 XkdT, Uncharacterized homolog of phage Mu protein gp47 Function unknown 125975716 Nonpathogen - hypothetical protein Cthe_3238 1 None None None 125974782 Common - CRISPR-associated protein Cas1 Cthe_2297 98 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 125974507 Common - hypothetical protein Cthe_2010 4 None None None 125975572 Common - glycosyl transferase, family 2 Cthe_3094 202 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 125973158 Common - cellulosome enzyme, dockerin type I Cthe_0640 8 COG5434 PGU1, Endopygalactorunase Cell envelope biogenesis, outer membrane 125973934 Common - protein of unknown function DUF204 Cthe_1420 66 COG1971 COG1971, Predicted membrane protein Function unknown 125974889 Common - transcriptional regulator, GntR family Cthe_2404 142 COG1802 GntR, Transcriptional regulators Transcription 125975393 Common rpsQ 30S ribosomal protein S17 Cthe_2912 234 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 125975559 Common - cellulosome anchoring protein, cohesin region Cthe_3080 23 None None None 125973699 Nonpathogen - hypothetical protein Cthe_1184 1 None None None 125973543 Common - acetate kinase Cthe_1028 162 COG0282 ackA, Acetate kinase Energy production and conversion 125972824 Nonpathogen - hypothetical protein Cthe_0303 1 None None None 125974308 Common - cell wall hydrolase/autolysin Cthe_1804 183 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 125975348 Nonpathogen - hypothetical protein Cthe_2867 1 None None None 125973099 Common - aspartate aminotransferase Cthe_0580 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 125973691 Common - CheC-like protein Cthe_1176 16 COG1406 COG1406, Predicted inhibitor of MCP methylation, homolog of CheC Cell motility and secretion 125974133 Common - phage head-tail adaptor, putative Cthe_1626 5 None None None 125974808 Common - transposase, IS4 Cthe_2323 28 None None None 125975655 Common - hypothetical protein Cthe_3177 23 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 125974093 Common - two component transcriptional regulator, AraC family Cthe_1584 219 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 125972820 Common - MATE efflux family protein Cthe_0299 180 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 125975304 Common - oxidoreductase-like protein Cthe_2822 176 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 125973205 Common - chromosome segregation and condensation protein ScpA Cthe_0687 140 COG1354 COG1354, Uncharacterized conserved protein Function unknown 125973284 Common - tRNA (guanine-N1)-methyltransferase Cthe_0766 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 125974245 Common - hypothetical protein Cthe_1741 3 None None None 125973907 Common - Integrase, catalytic region Cthe_1392 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 125974670 Common rpsR 30S ribosomal protein S18 Cthe_2185 215 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 125974199 Nonpathogen - hypothetical protein Cthe_1694 1 None None None 125974965 Nonpathogen - hypothetical protein Cthe_2480 1 None None None 125975557 Common - cellulosome anchoring protein, cohesin region Cthe_3078 25 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 125975610 Common - cellulosome enzyme, dockerin type I Cthe_3132 3 None None None 125973344 Nonpathogen - hypothetical protein Cthe_0826 1 None None None 125973757 Common - Integrase, catalytic region Cthe_1242 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 125973832 Common - hypothetical protein Cthe_1317 140 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 125972699 Common - polysaccharide deacetylase Cthe_0175 8 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 125973263 Common - glycoside hydrolase, family 9 Cthe_0745 17 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 125975356 Common - sigma 54 modulation protein/ribosomal protein S30EA Cthe_2875 170 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 125975329 Common - phage / plasmid primase, P4 family Cthe_2847 59 COG3378 COG3378, Predicted ATPase General function prediction only 125972551 Common - hypothetical protein Cthe_0027 3 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 125974590 Common - transcriptional regulator, AbrB family Cthe_2100 16 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 125975072 Common - hypothetical protein Cthe_2589 4 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 125975344 Common - conserved hypothetical protein precursor Cthe_2863 18 None None None 125973841 Common - GTP-binding protein LepA Cthe_1326 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 125974814 Nonpathogen - hypothetical protein Cthe_2329 2 COG4853 COG4853, Uncharacterized protein conserved in bacteria Function unknown 125973068 Common - ABC-3 Cthe_0549 193 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 125973138 Common - iron (metal) dependent repressor, DtxR family Cthe_0620 87 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 125973051 Common - hydrolase (HAD superfamily)-like protein Cthe_0532 27 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 125973958 Nonpathogen - uncharacterized Zn-finger protein Cthe_1445 1 None None None 125974423 Common - transcriptional regulator, PadR-like family Cthe_1921 45 COG1695 COG1695, Predicted transcriptional regulators Transcription 125973511 Common - DNA polymerase III PolC Cthe_0996 219 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 125973537 Common - Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) Cthe_1022 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 125975523 Common - protein of unknown function DUF975 Cthe_3044 11 COG5523 COG5523, Predicted integral membrane protein Function unknown 125973174 Common - type IV pilus assembly protein PilM Cthe_0656 73 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 125975584 Common - 6-pyruvoyl tetrahydropterin synthase and hypothetical protein Cthe_3106 136 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 125975271 Common - NLPA lipoprotein Cthe_2789 105 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 125974165 Common - TrkA-N Cthe_1659 131 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 125974105 Common - transcriptional regulator, MarR family Cthe_1596 20 COG1846 MarR, Transcriptional regulators Transcription 125974880 Common - transcriptional regulator, XRE family Cthe_2395 6 COG1396 HipB, Predicted transcriptional regulators Transcription 125975239 Common - potassium/proton antiporter Cthe_2757 99 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 125975422 Common - 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Cthe_2941 195 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 125973861 Common - single-stranded-DNA-specific exonuclease RecJ Cthe_1346 193 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 125973730 Common - permease Cthe_1215 129 COG0730 COG0730, Predicted permeases General function prediction only 125973337 Common - ABC transporter related protein Cthe_0819 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 125972753 Common - Radical SAM Cthe_0231 172 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 125973111 Nonpathogen - copper amine oxidase-like protein Cthe_0593 9 None None None 125974540 Nonpathogen - CRISPR-associated RAMP protein, SSO1426 family Cthe_2050 9 COG1337 COG1337, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 125974084 Common deoD purine nucleoside phosphorylase Cthe_1575 91 COG0813 DeoD, Purine-nucleoside phosphorylase Nucleotide transport and metabolism 125973129 Common - RNA-metabolising metallo-beta-lactamase Cthe_0611 125 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 125975542 Common - Acetyl xylan esterase Cthe_3063 20 COG3458 COG3458, Acetyl esterase (deacetylase) Secondary metabolites biosynthesis, transport, and catabolism 125974053 Common - aspartyl-tRNA synthetase Cthe_1543 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 125974557 Common - hypothetical protein Cthe_2067 11 COG1950 COG1950, Predicted membrane protein Function unknown 125974652 Common - glycoside hydrolase, family 8 Cthe_2167 6 COG3405 CelA, Endoglucanase Y Carbohydrate transport and metabolism 125973180 Nonpathogen - hypothetical protein Cthe_0662 1 None None None 125974411 Common - copper amine oxidase-like protein Cthe_1909 17 None None None 125975429 Common - Allergen V5/Tpx-1 related Cthe_2948 62 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 125974763 Common - extracellular solute-binding protein, family 3 Cthe_2278 142 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 125973756 Common - nicotinate (nicotinamide) nucleotide adenylyltransferase Cthe_1241 179 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 125974604 Common - Integrase, catalytic region Cthe_2114 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 125972962 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Cthe_0441 209 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 125972796 Common - glycoside hydrolase, family 9 Cthe_0274 18 None None None 125972945 Common - aminoglycoside phosphotransferase Cthe_0424 8 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 125973665 Nonpathogen - hypothetical protein Cthe_1150 1 None None None 125975066 Common - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase Cthe_2583 187 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 125972706 Common ruvB Holliday junction DNA helicase B Cthe_0182 224 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 125972715 Common - proteinase inhibitor I4, serpin Cthe_0191 31 COG4826 COG4826, Serine protease inhibitor Posttranslational modification, protein turnover, chaperones 125975550 Nonpathogen - protein of unknown function DUF1540 Cthe_3071 2 None None None 125973304 Common - 3-dehydroquinate synthase Cthe_0786 211 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 125975069 Common - amidohydrolase 2 Cthe_2586 49 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 125974313 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Cthe_1809 64 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 125974684 Common - IstB-like ATP-binding protein Cthe_2199 98 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 125975452 Common - glycoside hydrolase, family 11 Cthe_2972 102 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 125975643 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Cthe_3165 8 None None None 125972856 Common - hydrogenase large subunit-like protein Cthe_0335 48 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 125974943 Common - hypothetical protein Cthe_2458 4 None None None 125973442 Common - protein of unknown function DUF218 Cthe_0925 14 COG1434 COG1434, Uncharacterized conserved protein Function unknown 125973225 Common - Phosphoglycerate mutase Cthe_0707 192 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 125973424 Common - hypothetical protein Cthe_0907 7 None None None 125975248 Nonpathogen - hypothetical protein Cthe_2766 1 None None None 125972798 Common - 2-hydroxyacid dehydrogenase Cthe_0276 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 125973981 Common - Integrase, catalytic region Cthe_1469 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 125974102 Common - NUDIX hydrolase Cthe_1593 42 COG1443 Idi, Isopentenyldiphosphate isomerase Lipid metabolism 125975685 Common - transposase, mutator type Cthe_3207 89 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973105 Common - transposase IS3/IS911 Cthe_0586 39 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974066 Common - ABC transporter related protein Cthe_1557 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 125973438 Nonpathogen - hypothetical protein Cthe_0921 2 None None None 125974207 Nonpathogen - HNH endonuclease Cthe_1703 2 None None None 125972623 Common - 5,10-methylenetetrahydrofolate reductase Cthe_0099 161 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 125974717 Common - polysaccharide biosynthesis protein CapD Cthe_2232 204 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 125975214 Nonpathogen - hypothetical protein Cthe_2732 4 COG5660 COG5660, Predicted integral membrane protein Function unknown 125973082 Common - Heptaprenyl diphosphate synthase component I Cthe_0563 21 COG4769 COG4769, Predicted membrane protein Function unknown 125973606 Common - metal dependent phosphohydrolase Cthe_1091 82 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 125975478 Common - hypothetical protein Cthe_2999 2 None None None 125974214 Common - hypothetical protein Cthe_1710 1 None None None 125975139 Common - histone-like DNA-binding protein Cthe_2657 214 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 125972536 Nonpathogen - hypothetical protein Cthe_0011 1 None None None 125973528 Common - protein of unknown function UPF0118 Cthe_1013 119 COG0628 PerM, Predicted permease General function prediction only 125974225 Common - phage portal protein, HK97 family Cthe_1721 67 COG4695 COG4695, Phage-related protein Function unknown 125973811 Nonpathogen - hypothetical protein Cthe_1296 1 None None None 125972985 Common - flagellar hook-basal body complex subunit FliE Cthe_0464 95 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 125974186 Common - DNA polymerase, beta-like region Cthe_1680 16 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 125974993 Common - TOPRIM domain containing protein Cthe_2508 189 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 125973738 Common - ribosomal protein L20 Cthe_1223 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 125974489 Nonpathogen - hypothetical protein Cthe_1988 1 None None None 125973550 Common - DNA ligase, NAD-dependent Cthe_1035 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 125975283 Common - carbon-monoxide dehydrogenase, catalytic subunit Cthe_2801 24 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 125973189 Common - hypothetical protein Cthe_0671 5 None None None 125975624 Common - peptidase M56, BlaR1 Cthe_3146 30 COG4219 MecR1, Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component Transcription / Signal transduction mechanisms 125973444 Common - chromosome segregation protein SMC Cthe_0927 226 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 125973093 Common - serine/threonine protein kinase Cthe_0574 159 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 125973402 Common - dephospho-CoA kinase Cthe_0885 198 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 125974290 Common - DNA repair protein RadA Cthe_1786 234 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 125975325 Nonpathogen - hypothetical protein Cthe_2843 3 None None None 125974282 Nonpathogen - copper amine oxidase-like protein Cthe_1778 9 None None None 125974325 Common - inner-membrane translocator Cthe_1821 154 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 125975308 Common - hypothetical protein Cthe_2826 4 None None None 125973364 Common - hypothetical protein Cthe_0846 10 None None None 125973133 Common - Phenylacetate--CoA ligase Cthe_0615 129 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 125972966 Common - cell division protein FtsZ Cthe_0445 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 125975552 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Cthe_3073 202 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 125974503 Common - transposase Cthe_2004 84 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973272 Common - hypothetical protein Cthe_0754 5 None None None 125974297 Common - protein of unknown function DUF1624 Cthe_1793 21 COG3503 COG3503, Predicted membrane protein Function unknown 125975349 Common - transposase IS116/IS110/IS902 Cthe_2868 71 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974511 Nonpathogen - hypothetical protein Cthe_2015 1 None None None 125973251 Nonpathogen - type IV pilus assembly PilZ Cthe_0733 1 None None None 125974672 Common - ribosomal protein S6 Cthe_2187 193 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 125975002 Common - acetolactate synthase, small subunit Cthe_2517 193 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 125973714 Common - amidohydrolase Cthe_1199 182 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 125973223 Nonpathogen - hypothetical protein Cthe_0705 1 None None None 125974673 Common - Integrase, catalytic region Cthe_2188 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 125973125 Common - peptidase M42 Cthe_0607 90 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 125974901 Common - Propeptide, PepSY amd peptidase M4 Cthe_2416 14 None None None 125975527 Common - DNA repair protein RadC Cthe_3048 177 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 125975111 Common - UDP-N-acetylglucosamine pyrophosphorylase Cthe_2629 236 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 125973116 Common thiG thiazole synthase Cthe_0598 168 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 125974495 Common - hypothetical protein Cthe_1995 66 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 125975694 Common - transposase, mutator type Cthe_3216 89 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973801 Common - peptidase S1 and S6, chymotrypsin/Hap Cthe_1286 224 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 125974007 Common - Integrase, catalytic region Cthe_1496 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 125974666 Common - predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cthe_2181 170 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 125973635 Nonpathogen - hypothetical protein Cthe_1120 1 None None None 125972892 Common - transposase, mutator type Cthe_0371 89 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974261 Common - peptidase M23B Cthe_1757 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 125975426 Common - histidine kinase Cthe_2945 208 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 125974259 Nonpathogen - hypothetical protein Cthe_1755 1 None None None 125972873 Common - hypothetical protein Cthe_0352 33 COG3580 COG3580, Uncharacterized protein conserved in bacteria Function unknown 125975203 Common - ribosomal protein L1 Cthe_2721 239 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 125974606 Common - binding-protein-dependent transport systems inner membrane component Cthe_2116 146 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 125972656 Common - 3-oxoacyl-(acyl-carrier-protein) synthase Cthe_0132 193 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 125975409 Common - ribosomal protein L36 Cthe_2928 137 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 125973499 Common - prolipoprotein diacylglyceryl transferase Cthe_0984 197 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 125972736 Common - Beta-glucosidase Cthe_0212 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 125973457 Nonpathogen - hypothetical protein Cthe_0940 1 None None None 125975661 Common trkA potassium transporter peripheral membrane component Cthe_3183 163 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 125972650 Common - CheC-like protein Cthe_0126 27 COG1406 COG1406, Predicted inhibitor of MCP methylation, homolog of CheC Cell motility and secretion 125972704 Common - crossover junction endodeoxyribonuclease RuvC Cthe_0180 198 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 125975435 Common - hypothetical protein Cthe_2954 43 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974692 Common - isoaspartyl dipeptidase Cthe_2207 37 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 125972973 Nonpathogen - cellulosome anchoring protein, cohesin region Cthe_0452 1 None None None 125972742 Common - metallophosphoesterase Cthe_0218 101 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 125975494 Common - hydrogenase assembly chaperone hypC/hupF Cthe_3015 59 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 125975495 Common - (NiFe) hydrogenase maturation protein HypF Cthe_3016 115 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 125974013 Common - transcriptional regulator, MarR family Cthe_1502 115 COG1846 MarR, Transcriptional regulators Transcription 125974044 Nonpathogen - hypothetical protein Cthe_1534 1 None None None 125975367 Common - imidazole glycerol phosphate synthase, glutamine amidotransferase subunit Cthe_2886 216 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 125972673 Nonpathogen - HPrNtr domain containing protein Cthe_0149 3 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 125972866 Common - L-lactate dehydrogenase Cthe_0345 180 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 125974358 Common - methylated-DNA--protein-cysteine methyltransferase Cthe_1854 194 COG3695 COG3695, Predicted methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 125972991 Nonpathogen - hypothetical protein Cthe_0470 1 COG3334 COG3334, Uncharacterized conserved protein Function unknown 125973930 Nonpathogen - hypothetical protein Cthe_1416 1 None None None 125975525 Common - cell cycle protein Cthe_3046 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 125975143 Nonpathogen - Septum formation initiator Cthe_2661 1 None None None 125972573 Common - transcriptional regulator, XRE family Cthe_0049 4 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 125975374 Nonpathogen - response regulator receiver protein Cthe_2893 1 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 125974687 Common - hypothetical protein Cthe_2202 5 None None None 125972526 Common - Recombinase Cthe_0001 95 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 125972616 Common minC septum formation inhibitor Cthe_0092 71 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 125974122 Nonpathogen - hypothetical protein Cthe_1615 3 None None None 125972970 Common - hypothetical protein Cthe_0449 16 COG1873 COG1873, Uncharacterized conserved protein Function unknown 125973109 Common - Integrase, catalytic region Cthe_0591 153 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974289 Common - protein of unknown function DUF147 Cthe_1785 29 COG1623 COG1623, Predicted nucleic-acid-binding protein (contains the HHH domain) General function prediction only 125974114 Common - phosphate ABC transporter (binding protein)-like protein Cthe_1605 90 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 125974820 Common - polysaccharide biosynthesis protein Cthe_2335 98 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 125974348 Common - transcriptional regulator, BadM/Rrf2 family Cthe_1844 176 COG1959 COG1959, Predicted transcriptional regulator Transcription 125974884 Common - Formate--tetrahydrofolate ligase Cthe_2399 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 125975507 Common - histidine decarboxylase Cthe_3028 110 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 125975370 Common - phosphoribosyl-AMP cyclohydrolase Cthe_2889 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 125973513 Common - putative membrane-associated zinc metalloprotease Cthe_0998 211 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 125974161 Common - hypothetical protein Cthe_1655 8 COG3655 COG3655, Predicted transcriptional regulator Transcription 125974337 Common - copper amine oxidase-like protein Cthe_1833 10 None None None 125972609 Common - Negative regulator of genetic competence Cthe_0085 8 COG4862 MecA, Negative regulator of genetic competence, sporulation and motility Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Cell motility and secretion 125973469 Common - dihydroorotase, multifunctional complex type Cthe_0952 212 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 125975237 Common - ADP-ribosylation/Crystallin J1 Cthe_2755 52 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 125974552 Common - GerA spore germination protein Cthe_2062 15 None None None 125974827 Common - hypothetical protein Cthe_2342 23 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 125974129 Common - hypothetical protein Cthe_1622 6 None None None 125974967 Common - hypothetical protein Cthe_2482 2 None None None 125972663 Common - Triose-phosphate isomerase Cthe_0139 222 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 125972959 Nonpathogen - cellulosome enzyme, dockerin type I Cthe_0438 1 None None None 125972681 Common - hypothetical protein Cthe_0157 43 COG5011 COG5011, Uncharacterized protein conserved in bacteria Function unknown 125975481 Nonpathogen - hypothetical protein Cthe_3002 1 None None None 125974253 Common - DNA-cytosine methyltransferase Cthe_1749 120 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 125974999 Nonpathogen - hypothetical protein Cthe_2514 1 None None None 125972794 Common - Serine-type D-Ala-D-Ala carboxypeptidase Cthe_0272 156 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 125972556 Common - glycoside hydrolase, family 26 Cthe_0032 9 COG4124 ManB, Beta-mannanase Carbohydrate transport and metabolism 125974872 Common - peptidase M14, carboxypeptidase A Cthe_2387 38 COG2866 COG2866, Predicted carboxypeptidase Amino acid transport and metabolism 125972911 Common - ROK domain containing protein Cthe_0390 148 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 125975411 Common - 30S ribosomal protein S11 Cthe_2930 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 125974020 Common - protein of unknown function DUF438 Cthe_1509 27 COG2461 COG2461, Uncharacterized conserved protein Function unknown 125973595 Nonpathogen - carbohydrate binding family 25 Cthe_1080 5 None None None 125973651 Common - serine/threonine protein kinase with TPR repeats Cthe_1136 153 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 125972763 Common - hypothetical protein Cthe_0241 13 None None None 125972584 Common - hypothetical protein Cthe_0060 2 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 125975172 Common - phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase Cthe_2690 62 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 125972580 Common - Ig-like, group 2 Cthe_0056 63 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 125973700 Nonpathogen - hypothetical protein Cthe_1185 5 COG4908 COG4908, Uncharacterized protein containing a NRPS condensation (elongation) domain General function prediction only 125974720 Common - protein of unknown function DUF115 Cthe_2235 22 COG2604 COG2604, Uncharacterized protein conserved in bacteria Function unknown 125972867 Nonpathogen - hypothetical protein Cthe_0346 1 None None None 125975261 Nonpathogen - hypothetical protein Cthe_2779 1 COG4640 COG4640, Predicted membrane protein Function unknown 125973394 Common - translation-associated GTPase Cthe_0877 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 125974957 Nonpathogen - hypothetical protein Cthe_2472 1 None None None 125974616 Common - ATPase associated with various cellular activities, AAA_3 Cthe_2127 170 COG0714 COG0714, MoxR-like ATPases General function prediction only 125973379 Common - hypothetical protein Cthe_0862 3 None None None 125975032 Common - Alpha-N-arabinofuranosidase Cthe_2548 31 COG3534 AbfA, Alpha-L-arabinofuranosidase Carbohydrate transport and metabolism 125975338 Nonpathogen - hypothetical protein Cthe_2856 1 None None None 125972544 Common - regulatory protein, P-II family Cthe_0019 18 None None None 125972886 Common - peptide chain release factor 2 Cthe_0365 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 125974530 Nonpathogen - cellulosome enzyme, dockerin type I Cthe_2038 1 COG5434 PGU1, Endopygalactorunase Cell envelope biogenesis, outer membrane 125973293 Common - tRNA delta(2)-isopentenylpyrophosphate transferase Cthe_0775 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 125975154 Common - transposase, mutator type Cthe_2672 88 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973198 Common - Lysine exporter protein (LYSE/YGGA) Cthe_0680 27 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 125974239 Nonpathogen - phage DNA polymerase Cthe_1735 3 COG0417 PolB, DNA polymerase elongation subunit (family B) DNA replication, recombination, and repair 125972899 Nonpathogen - hypothetical protein Cthe_0378 2 None None None 125973679 Common - FAD dependent oxidoreductase Cthe_1164 80 COG2509 COG2509, Uncharacterized FAD-dependent dehydrogenases General function prediction only 125974275 Common - Rubrerythrin Cthe_1771 79 COG1592 COG1592, Rubrerythrin Energy production and conversion 125975616 Nonpathogen - hypothetical protein Cthe_3138 1 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 125974839 Common - nicotinate-nucleotide pyrophosphorylase Cthe_2354 205 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 125974834 Common - small, acid-soluble spore proteins, alpha/be Cthe_2349 12 None None None 125975058 Common - hypothetical protein Cthe_2575 41 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 125973322 Common - transcriptional regulator, MerR family Cthe_0804 7 COG0789 SoxR, Predicted transcriptional regulators Transcription 125975181 Common - transcriptional modulator of MazE/toxin, MazF Cthe_2699 61 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 125973230 Common - cytidylate kinase Cthe_0712 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 125974252 Common - hypothetical protein Cthe_1748 3 None None None 125974452 Nonpathogen - hypothetical protein Cthe_1951 1 None None None 125975245 Nonpathogen - hypothetical protein Cthe_2763 2 COG2378 COG2378, Predicted transcriptional regulator Transcription 125975125 Common - Nucleotidyl transferase Cthe_2643 190 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 125974860 Common - hypothetical protein Cthe_2375 12 None None None 125974172 Common - transposase, IS4 Cthe_1666 28 None None None 125975709 Nonpathogen - hypothetical protein Cthe_3231 1 None None None 125975490 Nonpathogen - hypothetical protein Cthe_3011 1 None None None 125973782 Common - two component transcriptional regulator, LuxR family Cthe_1267 223 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 125974944 Common - protein of unknown function DUF955 Cthe_2459 11 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 125974577 Common - metalloenzyme Cthe_2087 79 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 125973902 Nonpathogen - hypothetical protein Cthe_1387 1 None None None 125973722 Common - membrane protein-like protein Cthe_1207 8 COG5305 COG5305, Predicted membrane protein Function unknown 125975042 Common - NAD-dependent epimerase/dehydratase Cthe_2558 210 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 125973485 Common - UvrD/REP helicase Cthe_0968 231 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 125973338 Nonpathogen - hypothetical protein Cthe_0820 1 None None None 125974302 Common - redox-sensing transcriptional repressor Rex Cthe_1798 56 COG2344 COG2344, AT-rich DNA-binding protein General function prediction only 125974797 Common - hypothetical protein Cthe_2312 7 COG4939 COG4939, Major membrane immunogen, membrane-anchored lipoprotein Function unknown 125974731 Nonpathogen - anti-sigma-28 factor, FlgM Cthe_2246 11 COG2747 FlgM, Negative regulator of flagellin synthesis (anti-sigma28 factor) Transcription / Cell motility and secretion / Intracellular trafficking and secretion 125975402 Common - ribosomal protein L30 Cthe_2921 113 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 125974461 Common - Peptidoglycan-binding domain 1 Cthe_1960 39 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 125972926 Common - glycoside hydrolase, family 5 Cthe_0405 18 COG2730 BglC, Endoglucanase Carbohydrate transport and metabolism 125973329 Common - response regulator receiver protein Cthe_0811 221 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 125975576 Nonpathogen - hypothetical protein Cthe_3098 2 None None None 125974394 Common - cellulosome enzyme, dockerin type I Cthe_1890 13 None None None 125974152 Nonpathogen - hypothetical protein Cthe_1646 4 COG1591 COG1591, Holliday junction resolvase - archaeal type DNA replication, recombination, and repair 125975226 Common - Lytic transglycosylase, catalytic Cthe_2744 177 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 125974398 Common - transcriptional regulator, PadR-like family Cthe_1895 79 COG1695 COG1695, Predicted transcriptional regulators Transcription 125975051 Nonpathogen - hypothetical protein Cthe_2567 1 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 125974567 Common - CoA-binding protein Cthe_2077 153 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 125974150 Common - hypothetical protein Cthe_1644 1 None None None 125975057 Common - binding-protein-dependent transport systems inner membrane component Cthe_2574 165 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 125973748 Nonpathogen - hypothetical protein Cthe_1233 1 None None None 125974189 Nonpathogen - transposase IS3/IS911 Cthe_1684 5 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 125975383 Common - ribosomal protein S10 Cthe_2902 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 125973964 Nonpathogen - GCN5-related N-acetyltransferase Cthe_1451 1 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 125973626 Common - Bile acid:sodium symporter Cthe_1111 135 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 125972561 Common - heat shock protein Hsp20 Cthe_0037 174 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 125973217 Common - carboxyl transferase Cthe_0699 216 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 125972936 Common - spore coat protein CotJB Cthe_0415 9 None None None 125972693 Nonpathogen - dehydrogenase (flavoproteins) Cthe_0169 12 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 125975084 Common - UDP-N-acetylglucosamine 2-epimerase Cthe_2601 157 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 125973390 Common - anthranilate phosphoribosyltransferase Cthe_0873 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 125974573 Common - DNA-directed DNA polymerase Cthe_2083 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 125973744 Common - Spore germination protein-like protein Cthe_1229 22 COG5401 COG5401, Spore germination protein General function prediction only 125973414 Common - deoxyguanosinetriphosphate triphosphohydrolase-like protein Cthe_0897 165 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 125974429 Common - conserved hypothetical protein precursor Cthe_1928 17 None None None 125973043 Common - Resolvase-like protein Cthe_0523 112 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 125975297 Common - lysyl-tRNA synthetase Cthe_2815 77 COG1384 LysS, Lysyl-tRNA synthetase (class I) Translation, ribosomal structure and biogenesis 125972777 Nonpathogen - hypothetical protein Cthe_0255 1 None None None 125973301 Common - RNA modification enzyme, MiaB family Cthe_0783 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 125974812 Common - beta-lactamase-like protein Cthe_2327 61 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 125974211 Common - phage minor structural protein Cthe_1707 11 COG4926 PblB, Phage-related protein Function unknown 125974985 Nonpathogen - hypothetical protein Cthe_2500 3 None None None 125975600 Common - S-layer-like domain containing protein Cthe_3122 46 None None None 125974539 Nonpathogen - protein of unknown function DUF324 Cthe_2049 6 COG1337 COG1337, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 125973563 Common - Rhomboid-like protein Cthe_1048 158 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 125972827 Common - DNA gyrase/topoisomerase IV, subunit A Cthe_0306 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 125972859 Common - NADH-quinone oxidoreductase, E subunit Cthe_0338 157 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 125975691 Nonpathogen - hypothetical protein Cthe_3213 1 None None None 125973478 Common - aspartate-semialdehyde dehydrogenase Cthe_0961 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 125972934 Common - glycoside hydrolase, family 9 Cthe_0413 36 None None None 125974658 Common - Integrase, catalytic region Cthe_2173 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 125975358 Common - S-layer-like domain containing protein Cthe_2877 19 None None None 125972812 Common - Homoserine dehydrogenase Cthe_0290 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 125974980 Common - hypothetical protein Cthe_2495 36 COG3391 COG3391, Uncharacterized conserved protein Function unknown 125974304 Common - Peptidoglycan-binding LysM Cthe_1800 105 COG3858 COG3858, Predicted glycosyl hydrolase General function prediction only 125972826 Common - DNA topoisomerase (ATP-hydrolyzing) Cthe_0305 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 125974893 Nonpathogen - phage shock protein A, PspA Cthe_2408 2 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 125972846 Common nadE NAD synthetase Cthe_0325 192 COG0171 NadE, NAD synthase Coenzyme metabolism 125974787 Nonpathogen - hypothetical protein Cthe_2302 1 None None None 125975258 Nonpathogen - hypothetical protein Cthe_2776 1 None None None 125974384 Common - transposase IS3/IS911 Cthe_1880 39 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973969 Common - polar amino acid ABC transporter, inner membrane subunit Cthe_1457 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 125974490 Nonpathogen - hypothetical protein Cthe_1990 1 None None None 125972768 Common - Carbohydrate binding family 6 Cthe_0246 14 None None None 125975192 Common - Uncharacterized membrane protein-like protein Cthe_2710 23 COG3949 COG3949, Uncharacterized membrane protein Function unknown 125975336 Common - conserved hypothetical protein precursor Cthe_2854 20 COG5281 COG5281, Phage-related minor tail protein Function unknown 125973120 Common - thiamine biosynthesis protein ThiC Cthe_0602 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 125974470 Common - hypothetical protein Cthe_1969 4 None None None 125974754 Common - V-type ATP synthase subunit D Cthe_2269 44 COG1394 NtpD, Archaeal/vacuolar-type H+-ATPase subunit D Energy production and conversion 125974765 Common - ABC transporter related protein Cthe_2280 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 125974979 Nonpathogen - hypothetical protein Cthe_2494 1 None None None 125973648 Nonpathogen - hypothetical protein Cthe_1133 1 None None None 125974074 Common - Nitrogenase Cthe_1565 55 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 125973887 Nonpathogen - hypothetical protein Cthe_1372 1 None None None 125973688 Nonpathogen - type IV pilus assembly PilZ Cthe_1173 1 None None None 125973949 Common - Phosphoglycerate mutase Cthe_1435 61 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 125974509 Common - transposase IS3/IS911 Cthe_2013 39 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974034 Common - glycosyl transferase, group 1 Cthe_1523 139 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 125974748 Common - V-type ATP synthase subunit K Cthe_2263 20 None None None 125975658 Nonpathogen - hypothetical protein Cthe_3180 3 None None None 125973583 Common - cytidine deaminase Cthe_1068 124 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 125973932 Nonpathogen - hypothetical protein Cthe_1418 1 None None None 125973611 Nonpathogen - hypothetical protein Cthe_1096 3 None None None 125975574 Nonpathogen - hypothetical protein Cthe_3096 1 None None None 125972625 Common - iron-containing alcohol dehydrogenase Cthe_0101 170 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 125974459 Common uvsE putative UV damage endonuclease Cthe_1958 25 COG4294 Uve, UV damage repair endonuclease DNA replication, recombination, and repair 125973156 Common - FHA domain containing protein Cthe_0638 201 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 125972595 Common - Cellulose 1,4-beta-cellobiosidase Cthe_0071 11 None None None 125973912 Common - cellulosome enzyme, dockerin type I Cthe_1398 23 COG4447 COG4447, Uncharacterized protein related to plant photosystem II stability/assembly factor General function prediction only 125975714 Common - hypothetical protein Cthe_3236 2 None None None 125973849 Common - FHA domain containing protein Cthe_1334 11 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 125973314 Nonpathogen - hypothetical protein Cthe_0796 1 None None None 125974131 Common - hypothetical protein Cthe_1624 5 None None None 125974042 Common - flagellin-like protein Cthe_1532 66 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 125973286 Common - nucleic acid binding protein, containing KH domain Cthe_0768 69 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 125973546 Common - glutamyl-tRNA(Gln) amidotransferase, B subunit Cthe_1031 214 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 125973541 Common - ribosomal protein L32 Cthe_1026 66 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 125972822 Common - protein of unknown function DUF1212 Cthe_0301 21 COG2966 COG2966, Uncharacterized conserved protein Function unknown 125972534 Common - YD repeat containing protein Cthe_0009 80 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 125975262 Common - hypothetical protein Cthe_2780 17 COG5646 COG5646, Uncharacterized conserved protein Function unknown 125975346 Common - phage / plasmid primase, P4 family Cthe_2865 59 COG3378 COG3378, Predicted ATPase General function prediction only 125972589 Common - hypothetical protein Cthe_0065 8 None None None 125974050 Common - glutamyl-tRNA(Gln) amidotransferase, B subunit Cthe_1540 214 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 125973759 Common - glycosyl transferase, family 2 Cthe_1244 215 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 125973998 Common - NUDIX hydrolase Cthe_1486 171 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 125972761 Common - cellulosome enzyme, dockerin type I Cthe_0239 12 None None None 125973709 Common - hypothetical protein Cthe_1194 6 None None None 125975188 Common - ABC transporter related protein Cthe_2706 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 125973228 Common - hypothetical protein Cthe_0710 10 None None None 125975095 Nonpathogen - Fibronectin, type III Cthe_2612 2 None None None 125973940 Common - AzlC-like protein Cthe_1426 94 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 125974722 Common - flagellin-like protein Cthe_2237 120 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 125973247 Common - cellulosome enzyme, dockerin type I Cthe_0729 11 COG4907 COG4907, Predicted membrane protein Function unknown 125972931 Common - hypothetical protein Cthe_0410 48 COG2848 COG2848, Uncharacterized conserved protein Function unknown 125975702 Nonpathogen - hypothetical protein Cthe_3224 1 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 125973875 Common - polysaccharide biosynthesis protein CpsF Cthe_1360 13 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 125974592 Common - methyltransferase small Cthe_2102 72 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 125972908 Common - transposase, IS4 Cthe_0387 28 None None None 125974932 Common - ABC transporter related protein Cthe_2447 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 125975362 Common - ATP phosphoribosyltransferase Cthe_2881 214 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 125973250 Common - chorismate synthase Cthe_0732 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 125973084 Common - hypothetical protein Cthe_0565 2 COG3523 IcmF, Uncharacterized protein conserved in bacteria Function unknown 125973852 Common - type II secretion system protein Cthe_1337 59 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 125973962 Common - transcriptional regulator, MarR family Cthe_1449 66 COG1846 MarR, Transcriptional regulators Transcription 125974278 Common - ribosomal-protein-alanine acetyltransferase Cthe_1774 211 COG0456 RimI, Acetyltransferases General function prediction only 125973411 Nonpathogen - hypothetical protein Cthe_0894 2 None None None 125974614 Common - binding-protein-dependent transport systems inner membrane component Cthe_2125 140 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 125973062 Common - glycoside hydrolase, family 9 Cthe_0543 17 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 125974870 Common - hypothetical protein Cthe_2385 17 COG4803 COG4803, Predicted membrane protein Function unknown 125973892 Common - hypothetical protein Cthe_1377 14 COG4492 PheB, ACT domain-containing protein General function prediction only 125975322 Common - hypothetical protein Cthe_2840 3 None None None 125975129 Common - protein of unknown function DUF201 Cthe_2647 34 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 125972644 Common - RNA polymerase, sigma 28 subunit Cthe_0120 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 125974230 Common - hypothetical protein Cthe_1726 24 None None None 125973018 Common - protein of unknown function DUF342 Cthe_0498 37 COG1315 COG1315, Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain DNA replication, recombination, and repair 125975013 Common - uroporphyrin-III C-methyltransferase Cthe_2528 204 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 125973235 Common - MCP methyltransferase, CheR-type Cthe_0717 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 125973151 Nonpathogen - hypothetical protein Cthe_0633 1 None None None 125975014 Common - delta-aminolevulinic acid dehydratase Cthe_2529 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 125975314 Common - transposase, mutator type Cthe_2832 82 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973568 Common ldh L-lactate dehydrogenase Cthe_1053 166 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 125974372 Common - carbamoyl-phosphate synthase, large subunit Cthe_1868 237 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 125974055 Nonpathogen - hypothetical protein Cthe_1545 1 None None None 125975024 Common - UBA/THIF-type NAD/FAD binding fold Cthe_2539 216 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 125973521 Common - ribosomal protein S2 Cthe_1006 245 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 125974311 Nonpathogen - hypothetical protein Cthe_1807 7 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 125972712 Common - ribonuclease PH Cthe_0188 207 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 125973834 Common - protein of unknown function DUF558 Cthe_1319 203 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 125974621 Nonpathogen - hypothetical protein Cthe_2133 1 None None None 125974734 Common - helicase, RecD/TraA family Cthe_2249 146 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 125974862 Common - Cobyrinic acid a,c-diamide synthase Cthe_2377 235 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 125974938 Common - hypothetical protein Cthe_2453 42 COG1694 MazG, Predicted pyrophosphatase General function prediction only 125973903 Common - TrpR like protein, YerC/YecD Cthe_1388 21 COG4496 COG4496, Uncharacterized protein conserved in bacteria Function unknown 125974602 Common - two component transcriptional regulator, winged helix family Cthe_2112 209 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 125974005 Common - protein of unknown function DUF6, transmembrane Cthe_1494 56 COG2510 COG2510, Predicted membrane protein Function unknown 125973923 Common - periplasmic sensor signal transduction histidine kinase Cthe_1409 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 125974466 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Cthe_1965 223 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 125973270 Nonpathogen - hypothetical protein Cthe_0752 2 None None None 125975609 Common - von Willebrand factor, type A Cthe_3131 12 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 125973618 Nonpathogen - prepilin-type cleavage/methylation Cthe_1103 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 125973970 Common - extracellular solute-binding protein, family 3 Cthe_1458 141 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 125974432 Common - S-layer-like domain containing protein Cthe_1931 19 None None None 125975070 Nonpathogen - hypothetical protein Cthe_2587 1 None None None 125974284 Nonpathogen - hypothetical protein Cthe_1780 2 None None None 125973863 Common - ribosomal protein S21 Cthe_1348 113 None None None 125974405 Common - polysaccharide deacetylase Cthe_1903 63 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 125975223 Common clpX ATP-dependent protease ATP-binding subunit Cthe_2741 221 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 125975385 Common - ribosomal protein L4/L1e Cthe_2904 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 125975562 Nonpathogen - hypothetical protein Cthe_3083 1 None None None 125973422 Common - metal dependent phosphohydrolase Cthe_0905 17 COG3294 COG3294, Uncharacterized conserved protein Function unknown 125975289 Common - glycoside hydrolase, family 5 Cthe_2807 24 COG2730 BglC, Endoglucanase Carbohydrate transport and metabolism 125973663 Common - hypothetical protein Cthe_1148 4 None None None 125972772 Common - protein of unknown function UPF0027 Cthe_0250 121 COG1690 RtcB, Uncharacterized conserved protein Function unknown 125974224 Common - peptidase S14, ClpP Cthe_1720 128 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 125974439 Common - D-alanine--D-alanine ligase Cthe_1938 222 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 125972960 Common - CobB/CobQ-like glutamine amidotransferase Cthe_0439 48 COG3442 COG3442, Predicted glutamine amidotransferase General function prediction only 125973429 Common - glycoside hydrolase, family 10 Cthe_0912 37 COG3693 XynA, Beta-1,4-xylanase Carbohydrate transport and metabolism 125975246 Common - TROVE domain containing protein Cthe_2764 18 None None None 125973982 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Cthe_1470 152 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 125972858 Common - PHP-like protein Cthe_0337 26 COG1379 COG1379, Uncharacterized conserved protein Function unknown 125974928 Common - Transketolase-like protein Cthe_2443 220 COG3959 COG3959, Transketolase, N-terminal subunit Carbohydrate transport and metabolism 125973435 Nonpathogen - cellulosome enzyme, dockerin type I Cthe_0918 1 None None None 125973302 Nonpathogen - hypothetical protein Cthe_0784 1 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 125974647 Common - peptidase C26 Cthe_2162 121 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 125975509 Common - methyl-accepting chemotaxis sensory transducer Cthe_3030 155 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 125973258 Common - transcriptional regulator, GntR family Cthe_0740 135 COG2188 PhnF, Transcriptional regulators Transcription 125973826 Common - signal transduction histidine kinase regulating citrate/malate metabolism Cthe_1311 43 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 125975212 Common - elongation factor Tu Cthe_2730 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 125975476 Nonpathogen - hypothetical protein Cthe_2997 1 None None None 125975671 Common - phospholipase C zinc-binding Cthe_3193 7 None None None 125973107 Common - Integrase, catalytic region Cthe_0588 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 125973608 Common - Methenyltetrahydrofolate cyclohydrolase Cthe_1093 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 125974205 Common - Recombinase Cthe_1701 111 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 125975295 Common - two component transcriptional regulator, winged helix family Cthe_2813 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 125973261 Common - MATE efflux family protein Cthe_0743 174 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 125975047 Nonpathogen - hypothetical protein Cthe_2563 2 None None None 125975592 Common - glycosyl transferase, group 1 Cthe_3114 107 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 125975443 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Cthe_2963 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 125973598 Common - Putative homoserine kinase type II (protein kinase fold)-like protein Cthe_1083 7 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 125974076 Nonpathogen - Dinitrogenase iron-molybdenum cofactor biosynthesis Cthe_1567 19 COG1433 COG1433, Uncharacterized conserved protein Function unknown 125975003 Common - ketol-acid reductoisomerase Cthe_2518 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 125972964 Common - protein of unknown function DUF1290 Cthe_0443 25 COG3856 Sbp, Uncharacterized conserved protein (small basic protein) Function unknown 125974921 Nonpathogen - hypothetical protein Cthe_2436 1 None None None 125973812 Common cobT nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Cthe_1297 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 125972943 Common - redox-sensing transcriptional repressor Rex Cthe_0422 56 COG2344 COG2344, AT-rich DNA-binding protein General function prediction only 125974549 Common - RNA polymerase factor sigma-70 Cthe_2059 91 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 125974843 Common - Accessory gene regulator B Cthe_2358 6 COG4512 AgrB, Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Transcription 125974090 Common - inner-membrane translocator Cthe_1581 159 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 125974383 Nonpathogen - hypothetical protein Cthe_1879 1 None None None 125973552 Common - cell wall hydrolase/autolysin Cthe_1037 184 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 125973502 Common - riboflavin biosynthesis protein RibF Cthe_0987 211 COG0196 RibF, FAD synthase Coenzyme metabolism 125975137 Common - transcriptional regulator, AbrB family Cthe_2655 16 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 125975132 Common - polysaccharide biosynthesis protein CapD Cthe_2650 211 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 125975533 Nonpathogen - hypothetical protein Cthe_3054 1 None None None 125974710 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Cthe_2225 58 None None None 125973766 Common - Xanthine/uracil/vitamin C permease Cthe_1251 136 COG2252 COG2252, Permeases General function prediction only 125973354 Nonpathogen - hypothetical protein Cthe_0836 7 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 125973161 Common - hypothetical protein Cthe_0643 25 COG3949 COG3949, Uncharacterized membrane protein Function unknown 125973693 Common - isochorismatase hydrolase Cthe_1178 32 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 125973275 Common - DNA repair protein RadC Cthe_0757 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 125973530 Common - hypothetical protein Cthe_1015 11 None None None 125972817 Common - hypothetical protein Cthe_0296 10 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 125973956 Common - hypothetical protein Cthe_1443 5 None None None 125973203 Common - peptidase M50 Cthe_0685 97 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 125974247 Common - protein of unknown function DUF955 Cthe_1743 9 None None None 125973136 Common - ferrous iron transport protein B Cthe_0618 163 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 125975379 Common - anti-sigma-factor antagonist Cthe_2898 63 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 125973539 Common - small GTP-binding protein Cthe_1024 231 COG1160 COG1160, Predicted GTPases General function prediction only 125973624 Common - permease Cthe_1109 71 COG0701 COG0701, Predicted permeases General function prediction only 125973993 Common - membrane protein-like protein Cthe_1481 62 COG1511 COG1511, Predicted membrane protein Function unknown 125974240 Nonpathogen - hypothetical protein Cthe_1736 2 None None None 125974193 Common - Radical SAM Cthe_1688 183 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 125974296 Common - Firmicute transcriptional repressor of class III stress genes Cthe_1792 22 COG4463 CtsR, Transcriptional repressor of class III stress genes Transcription 125975517 Nonpathogen - hypothetical protein Cthe_3038 2 None None None 125974480 Common - conserved hypothetical protein precursor Cthe_1979 16 COG5185 HEC1, Protein involved in chromosome segregation, interacts with SMC proteins Cell division and chromosome partitioning 125973335 Common - diguanylate cyclase Cthe_0817 205 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 125975342 Common - hypothetical protein Cthe_2861 4 None None None 125973387 Common - NADPH-dependent FMN reductase Cthe_0870 122 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 125975617 Common - hypothetical protein Cthe_3139 4 None None None 125972996 Nonpathogen - flagellar protein Cthe_0475 9 COG1582 FlgEa, Uncharacterized protein, possibly involved in motility Cell motility and secretion 125972988 Common - Flagellar biosynthesis/type III secretory pathway protein-like protein Cthe_0467 41 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 125973500 Common - peptidase M16-like protein Cthe_0985 184 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 125974167 Common - Integrase, catalytic region Cthe_1661 153 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974098 Common - transcriptional repressor, CopY family Cthe_1589 13 COG3682 COG3682, Predicted transcriptional regulator Transcription 125975278 Common - pyruvate flavodoxin/ferredoxin oxidoreductase-like protein Cthe_2796 137 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 125973736 Common - glycosyltransferase 36 Cthe_1221 48 COG3459 COG3459, Cellobiose phosphorylase Carbohydrate transport and metabolism 125973976 Common - Endoribonuclease L-PSP Cthe_1464 24 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 125972954 Common - glycoside hydrolase, family 9 Cthe_0433 18 None None None 125973182 Common - hypothetical protein Cthe_0664 9 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 125974852 Common - 60 kDa inner membrane insertion protein Cthe_2367 214 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 125972675 Common - hypothetical protein Cthe_0151 24 COG4472 COG4472, Uncharacterized protein conserved in bacteria Function unknown 125972847 Nonpathogen - hypothetical protein Cthe_0326 1 None None None 125973208 Common - hypothetical protein Cthe_0690 6 None None None 125974158 Nonpathogen - hypothetical protein Cthe_1652 3 None None None 125973750 Common - Cellulose 1,4-beta-cellobiosidase Cthe_1235 89 COG1572 COG1572, Uncharacterized conserved protein Function unknown 125975466 Nonpathogen - hypothetical protein Cthe_2987 1 None None None 125973070 Common - AMP-dependent synthetase and ligase Cthe_0551 222 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 125972756 Common - AMP-dependent synthetase and ligase Cthe_0234 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 125973034 Common - DNA methylase N-4/N-6 Cthe_0514 25 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 125972995 Common - protein of unknown function DUF1078-like protein Cthe_0474 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 125973720 Common - putative serine protein kinase, PrkA Cthe_1205 72 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 125972839 Common - ErfK/YbiS/YcfS/YnhG Cthe_0318 65 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 125973214 Common - putative rRNA methylase Cthe_0696 31 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 125974668 Common - UTP-glucose-1-phosphate uridylyltransferase Cthe_2183 232 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 125973130 Common - SSS sodium solute transporter superfamily Cthe_0612 127 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 125974851 Common - single-stranded nucleic acid binding R3H Cthe_2366 70 COG1847 Jag, Predicted RNA-binding protein General function prediction only 125974457 Common - Tagatose-6-phosphate kinase Cthe_1956 140 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 125972618 Common - Septum formation topological specificity factor MinE Cthe_0094 43 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 125975276 Common - pyruvate/ketoisovalerate oxidoreductase, gamma subunit Cthe_2794 68 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 125975241 Common - transcriptional regulator, AraC family Cthe_2759 69 COG3708 COG3708, Uncharacterized protein conserved in bacteria Function unknown 125974487 Common - phage / plasmid primase, P4 family Cthe_1986 64 COG3378 COG3378, Predicted ATPase General function prediction only 125973407 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Cthe_0890 175 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 125972730 Common - UvrD/REP helicase Cthe_0206 225 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 125973815 Nonpathogen - hypothetical protein Cthe_1300 4 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 125974137 Common - phage portal protein, HK97 family Cthe_1630 71 COG4695 COG4695, Phage-related protein Function unknown 125974431 Common - carboxyl-terminal protease Cthe_1930 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 125973356 Nonpathogen - hypothetical protein Cthe_0838 3 None None None 125975639 Common - Pseudouridine synthase, Rsu Cthe_3161 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 125975645 Common - glucose-1-phosphate adenylyltransferase, GlgD subunit Cthe_3167 161 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 125975606 Nonpathogen - iron-sulfur flavoprotein Cthe_3128 3 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 125973525 Common - peptidase U32 Cthe_1010 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 125972864 Common - flavin reductase-like, FMN-binding Cthe_0343 105 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 125974680 Common - Carbohydrate binding family 6 Cthe_2195 23 None None None 125974255 Common - RNA methyltransferase, TrmA family Cthe_1751 197 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 125974288 Common - hypothetical protein Cthe_1784 9 None None None 125974421 Common - MgtC/SapB transporter Cthe_1919 118 COG1285 SapB, Uncharacterized membrane protein Function unknown 125975579 Common - L,L-diaminopimelate aminotransferase Cthe_3101 233 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 125972861 Common - ferredoxin Cthe_0340 24 COG3411 COG3411, Ferredoxin Energy production and conversion 125973266 Common - binding-protein-dependent transport systems inner membrane component Cthe_0748 173 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 125974617 Common - extracellular solute-binding protein, family 1 Cthe_2128 15 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 125975487 Common - Superoxide dismutase Cthe_3008 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 125973320 Nonpathogen - hypothetical protein Cthe_0802 1 None None None 125974909 Nonpathogen - copper amine oxidase-like protein Cthe_2424 9 None None None 125973367 Common - 3-dehydroquinate dehydratase, type II Cthe_0849 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 125972838 Nonpathogen - hypothetical protein Cthe_0317 1 None None None 125975161 Common - Tetratricopeptide TPR_2 Cthe_2679 9 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 125973882 Common - PHP-like protein Cthe_1367 40 COG4464 CapC, Capsular polysaccharide biosynthesis protein Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 125973576 Common - hypothetical protein Cthe_1061 15 COG1655 COG1655, Uncharacterized protein conserved in bacteria Function unknown 125975423 Common - ABC transporter related protein Cthe_2942 249 COG4555 NatA, ABC-type Na+ transport system, ATPase component Energy production and conversion / Inorganic ion transport and metabolism 125974997 Common - protein of unknown function DUF951 Cthe_2512 27 COG4481 COG4481, Uncharacterized protein conserved in bacteria Function unknown 125973701 Common - Alpha/beta hydrolase fold-3 Cthe_1186 125 COG0657 Aes, Esterase/lipase Lipid metabolism 125975361 Common - histidyl-tRNA synthetase Cthe_2880 249 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 125975408 Common - translation initiation factor IF-1 Cthe_2927 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 125973672 Nonpathogen - hypothetical protein Cthe_1157 1 None None None 125974026 Common - GCN5-related N-acetyltransferase Cthe_1515 21 COG3153 COG3153, Predicted acetyltransferase General function prediction only 125975055 Common - hypothetical protein Cthe_2572 2 None None None 125974218 Common - hypothetical protein Cthe_1714 2 None None None 125974534 Nonpathogen - hypothetical protein Cthe_2044 1 None None None 125973491 Common - phospho-N-acetylmuramoyl-pentapeptide-transferase Cthe_0976 222 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 125973493 Common - UDP-N-acetylmuramyl-tripeptide synthetases Cthe_0978 210 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 125975292 Common - Na/Pi-cotransporter II-related protein Cthe_2810 109 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 125973593 Nonpathogen - hypothetical protein Cthe_1078 2 None None None 125972630 Common - GTP cyclohydrolase II Cthe_0106 232 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 125973017 Common - Integrase, catalytic region Cthe_0496 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 125974233 Common - DNA methylase N-4/N-6 Cthe_1729 85 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 125974450 Nonpathogen - hypothetical protein Cthe_1949 1 None None None 125973291 Common - SOS-response transcriptional repressor, LexA Cthe_0773 174 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 125972876 Common - hypothetical protein Cthe_0355 35 COG1379 COG1379, Uncharacterized conserved protein Function unknown 125973658 Nonpathogen - hypothetical protein Cthe_1143 1 None None None 125974837 Common - putative signal-transduction protein with CBS domains Cthe_2352 200 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 125975174 Common - glycosyl transferase, group 1 Cthe_2692 222 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 125975630 Common cobS cobalamin synthase Cthe_3152 86 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 125974378 Common - transposase, mutator type Cthe_1874 89 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 125975511 Nonpathogen - hypothetical protein Cthe_3032 2 COG4640 COG4640, Predicted membrane protein Function unknown 125974955 Common - DNA adenine methylase Cthe_2470 104 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 125973619 Common - prepilin-type cleavage/methylation Cthe_1104 13 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 125974831 Nonpathogen - O-antigen polymerase Cthe_2346 10 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 125973824 Common - Radical SAM Cthe_1309 145 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 125975205 Common - ribosomal protein L7/L12 Cthe_2723 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 125975184 Common - polysaccharide pyruvyl transferase Cthe_2702 230 COG2327 WcaK, Uncharacterized conserved protein Function unknown 125975650 Common - protein of unknown function DUF214 Cthe_3172 152 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 125974174 Common - ABC transporter related protein Cthe_1668 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 125974195 Common - Radical SAM Cthe_1690 183 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 125972888 Common - NADP oxidoreductase, coenzyme F420-dependent Cthe_0367 56 COG5495 COG5495, Uncharacterized conserved protein Function unknown 125974360 Common - small acid-soluble spore protein beta Cthe_1856 5 None None None 125973712 Common - conserved hypothetical protein precursor Cthe_1197 20 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 125975035 Common - Radical SAM Cthe_2551 82 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 125972725 Common - glutamate synthase, alpha subunit-like protein Cthe_0201 106 COG0070 GltB, Glutamate synthase domain 3 Amino acid transport and metabolism 125972811 Common - DEAD_2 Cthe_0289 100 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 125974177 Common - Recombinase Cthe_1671 87 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 125974303 Common - ABC transporter related protein Cthe_1799 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 125972918 Common - ABC transporter related protein Cthe_0397 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 125974650 Common - protein of unknown function DUF1256 Cthe_2165 14 None None None 125973371 Common - shikimate 5-dehydrogenase Cthe_0854 224 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 125974882 Common - hypothetical protein Cthe_2397 8 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 125973083 Common - Trans-hexaprenyltranstransferase Cthe_0564 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 125974646 Nonpathogen - hypothetical protein Cthe_2161 1 None None None 125974322 Common - urease, gamma subunit Cthe_1818 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 125973071 Common - transcriptional regulator, XRE family with cupin sensor Cthe_0552 96 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 125975152 Nonpathogen - hypothetical protein Cthe_2670 1 None None None 125974441 Common - RDD domain containing protein Cthe_1940 8 COG1714 COG1714, Predicted membrane protein/domain Function unknown 125974062 Common - hypothetical protein Cthe_1553 7 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 125973238 Common - aminotransferase, class V Cthe_0720 240 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 125974795 Common - hypothetical protein Cthe_2310 2 None None None 125975696 Common - CRISPR-associated protein Cas1 Cthe_3218 107 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 125973327 Common - CheW protein Cthe_0809 134 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 125974162 Common - Integrase, catalytic region Cthe_1656 153 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 125972669 Common - metal dependent phosphohydrolase Cthe_0145 31 COG2316 COG2316, Predicted hydrolase (HD superfamily) General function prediction only 125975707 Common - transposase, IS4 Cthe_3229 12 None None None 125972585 Common - BioY protein Cthe_0061 93 COG1268 BioY, Uncharacterized conserved protein General function prediction only 125975607 Common - Citrate transporter Cthe_3129 49 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 125975520 Common - 1,4-dihydroxy-2-naphthoate octaprenyltransferase Cthe_3041 55 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 125973240 Common - tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase Cthe_0722 215 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 125973788 Common - alpha-L-arabinofuranosidase B Cthe_1273 14 COG3889 COG3889, Predicted solute binding protein General function prediction only 125973942 Common - glycoside hydrolase, family 1 Cthe_1428 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 125975583 Common - exsB protein Cthe_3105 178 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 125973455 Common - fatty acid biosynthesis transcriptional regulator Cthe_0938 18 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 125975094 Common - Fibronectin, type III Cthe_2611 4 None None None 125975621 Common - hypothetical protein Cthe_3143 2 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 125973664 Nonpathogen - hypothetical protein Cthe_1149 1 None None None 125973873 Common - glycosyltransferase Cthe_1358 18 None None None 125974681 Common - Carbohydrate binding family 6 Cthe_2196 28 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 125973483 Nonpathogen - hypothetical protein Cthe_0966 1 None None None 125975210 Common - 30S ribosomal protein S7 Cthe_2728 249 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 125972671 Common - protein of unknown function DUF523 Cthe_0147 54 COG1683 COG1683, Uncharacterized conserved protein Function unknown 125975027 Nonpathogen - SirA-like protein Cthe_2542 10 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 125974266 Common - efflux transporter, RND family, MFP subunit Cthe_1762 175 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 125974903 Common - DNA replication protein DnaC Cthe_2418 46 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 125974327 Common - Extracellular ligand-binding receptor Cthe_1823 144 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 125974204 Common - Recombinase Cthe_1700 99 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 125973527 Common - sporulation sigma factor SigK Cthe_1012 213 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 125974669 Common - putative ribonuclease BN Cthe_2184 146 COG1295 Rbn, Predicted membrane protein Function unknown 125972940 Common - peptidase M16-like protein Cthe_0419 189 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 125975118 Common - integral membrane protein MviN Cthe_2636 216 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 125974248 Common - hypothetical protein Cthe_1744 2 None None None 125973855 Nonpathogen - hypothetical protein Cthe_1340 3 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 125974526 Common - hypothetical protein Cthe_2032 11 None None None 125973007 Common - GTP-binding signal recognition particle SRP54, G-domain Cthe_0486 247 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 125972744 Common - transposase, IS4 Cthe_0220 28 None None None 125973461 Common - SMC protein-like protein Cthe_0944 102 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 125973632 Common - Tn7-like transposition protein A Cthe_1117 18 None None None 125974341 Nonpathogen - hypothetical protein Cthe_1837 1 None None None 125975222 Common - ATP-dependent Clp protease, proteolytic subunit ClpP Cthe_2740 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 125974826 Common - glycosyl transferase, family 2 Cthe_2341 122 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 125973231 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase Cthe_0713 132 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 125973003 Common - flagellar biosynthetic protein FliQ Cthe_0482 108 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 125973466 Common carB carbamoyl phosphate synthase large subunit Cthe_0949 237 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 125975113 Common - peptidyl-tRNA hydrolase Cthe_2631 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 125973446 Common - Stage V sporulation protein S Cthe_0929 24 COG2359 SpoVS, Uncharacterized protein conserved in bacteria Function unknown 125975536 Common - transposase Cthe_3057 21 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973192 Common - NUDIX hydrolase Cthe_0674 187 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 125973939 Common hppA membrane-bound proton-translocating pyrophosphatase Cthe_1425 98 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 125973257 Nonpathogen - hypothetical protein Cthe_0739 1 COG1520 COG1520, FOG: WD40-like repeat Function unknown 125975392 Common - ribosomal protein L29 Cthe_2911 45 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 125975275 Common - aminotransferase, class I and II Cthe_2793 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 125974578 Common - protein of unknown function DUF710 Cthe_2088 17 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 125973019 Nonpathogen - hypothetical protein Cthe_0499 2 None None None 125974623 Common - transposase IS3/IS911 Cthe_2136 39 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974293 Common - ATPase AAA-2 Cthe_1789 229 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 125975046 Common - glucose-1-phosphate cytidylyltransferase Cthe_2562 141 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 125973183 Common - HflK protein Cthe_0665 204 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 125974610 Common - putative RNA polymerase sigma factor SigI Cthe_2120 14 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 125975256 Common - hypothetical protein Cthe_2774 2 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 125972953 Nonpathogen - hypothetical protein Cthe_0432 1 None None None 125975302 Common - MCP methyltransferase, CheR-type Cthe_2820 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 125974607 Common - putative sulfonate transport system substrate-binding protein Cthe_2117 115 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 125974564 Common - protein of unknown function DUF378 Cthe_2074 8 COG2155 COG2155, Uncharacterized conserved protein Function unknown 125975309 Nonpathogen - hypothetical protein Cthe_2827 1 None None None 125972600 Nonpathogen - hypothetical protein Cthe_0076 1 COG4980 GvpP, Gas vesicle protein General function prediction only 125975664 Common - Radical SAM Cthe_3186 95 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 125972923 Nonpathogen - copper amine oxidase-like protein Cthe_0402 9 None None None 125975598 Common - pyruvate flavodoxin/ferredoxin oxidoreductase-like protein Cthe_3120 110 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 125975311 Common - ISDet4, transposase Cthe_2829 64 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974875 Common - pyruvate/ketoisovalerate oxidoreductase, gamma subunit Cthe_2390 65 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 125973584 Common - protein of unknown function UPF0054 Cthe_1069 198 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 125975504 Nonpathogen - hypothetical protein Cthe_3025 1 None None None 125974694 Common - 3-isopropylmalate dehydrogenase Cthe_2209 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 125974517 Nonpathogen - hypothetical protein Cthe_2022 1 None None None 125972787 Common - aminotransferase, class V Cthe_0265 156 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 125975004 Common - putative alpha-isopropylmalate/homocitrate synthase family transferase Cthe_2519 214 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 125972546 Common - dethiobiotin synthase Cthe_0021 165 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 125973118 Common - thiamine biosynthesis protein ThiF Cthe_0600 193 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 125974067 Common - transcriptional regulator, BadM/Rrf2 family Cthe_1558 132 COG1959 COG1959, Predicted transcriptional regulator Transcription 125975497 Common - hydrogenase expression/synthesis, HypA Cthe_3018 81 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 125972901 Nonpathogen - hypothetical protein Cthe_0380 1 None None None 125975659 Common - Integrase, catalytic region Cthe_3181 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 125974032 Nonpathogen - hypothetical protein Cthe_1521 1 None None None 125974149 Common - Uncharacterized phage-associated protein-like protein Cthe_1643 28 COG3600 GepA, Uncharacterized phage-associated protein Function unknown 125972773 Nonpathogen - transglutaminase-like protein Cthe_0251 6 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 125975288 Nonpathogen - hypothetical protein Cthe_2806 1 None None None 125974427 Common - conserved hypothetical protein precursor Cthe_1926 16 None None None 125974716 Common - Methyltransferase type 11 Cthe_2231 26 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 125972626 Common trmB tRNA (guanine-N(7))-methyltransferase Cthe_0102 153 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 125973799 Common - glycogen/starch synthases, ADP-glucose type Cthe_1284 143 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 125974961 Common - phage putative head morphogenesis protein, SPP1 gp7 family Cthe_2476 11 COG5585 COG5585, NAD+--asparagine ADP-ribosyltransferase Signal transduction mechanisms 125973348 Common - acid phosphatase/vanadium-dependent haloperoxidase related Cthe_0830 26 COG1963 COG1963, Uncharacterized protein conserved in bacteria Function unknown 125975529 Common - Fibronectin, type III Cthe_3050 28 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 125974003 Common - NAD(P)H dehydrogenase (quinone) Cthe_1492 37 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 125975176 Common - O-antigen polymerase Cthe_2694 38 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 125974169 Common - Endoribonuclease L-PSP Cthe_1663 67 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 125974741 Common - replicative DNA helicase Cthe_2256 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 125973389 Common - Indole-3-glycerol-phosphate synthase Cthe_0872 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 125973573 Common - Glycine hydroxymethyltransferase Cthe_1058 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 125975396 Common - ribosomal protein L5 Cthe_2915 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 125974119 Common - toxin secretion/phage lysis holin Cthe_1612 13 COG4824 COG4824, Phage-related holin (Lysis protein) General function prediction only 125975334 Nonpathogen - hypothetical protein Cthe_2852 1 None None None 125973800 Common - metal dependent phosphohydrolase Cthe_1285 124 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 125973085 Common - primosomal protein N' Cthe_0566 212 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 125973178 Common - glycoside hydrolase, family 81 Cthe_0660 6 COG5498 ACF2, Predicted glycosyl hydrolase Cell envelope biogenesis, outer membrane 125974518 Common - transposase IS116/IS110/IS902 Cthe_2024 68 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974202 Common - transcriptional regulator, ArsR family Cthe_1697 153 COG0640 ArsR, Predicted transcriptional regulators Transcription 125975457 Nonpathogen - MAEBL, putative Cthe_2977 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 125975445 Common - binding-protein-dependent transport systems inner membrane component Cthe_2965 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 125975135 Common - hypothetical protein Cthe_2653 206 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 125973016 Common - RNA polymerase, sigma 28 subunit Cthe_0495 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 125974106 Common - flavodoxin Cthe_1597 10 COG0716 FldA, Flavodoxins Energy production and conversion 125974864 Common - hypothetical protein Cthe_2379 13 None None None 125973809 Common - Recombinase Cthe_1294 86 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 125972955 Common - ATPase Cthe_0434 10 COG1703 ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family Amino acid transport and metabolism 125973669 Nonpathogen - transcriptional regulator, XRE family Cthe_1154 5 None None None 125973209 Common - hypothetical protein Cthe_0691 17 COG3874 COG3874, Uncharacterized conserved protein Function unknown 125973578 Common - thiamine biosynthesis/tRNA modification protein ThiI Cthe_1063 95 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 125972767 Common - transcriptional regulator, ArsR family Cthe_0245 160 COG0640 ArsR, Predicted transcriptional regulators Transcription 125975648 Common - ABC transporter related protein Cthe_3170 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 125973995 Nonpathogen - hypothetical protein Cthe_1483 3 None None None 125973605 Common - hypothetical protein Cthe_1090 81 COG1692 COG1692, Uncharacterized protein conserved in bacteria Function unknown 125973753 Common - iojap-like protein Cthe_1238 201 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 125973978 Common - protein of unknown function DUF1706 Cthe_1466 22 COG4283 COG4283, Uncharacterized conserved protein Function unknown 125972695 Nonpathogen - hypothetical protein Cthe_0171 3 None None None 125974386 Nonpathogen - hypothetical protein Cthe_1882 1 None None None 125975076 Common - peptide chain release factor 1 Cthe_2593 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 125972702 Common - argininosuccinate lyase Cthe_0178 238 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 125975468 Common - glycosyltransferase 36 Cthe_2989 43 COG3459 COG3459, Cellobiose phosphorylase Carbohydrate transport and metabolism 125975235 Common - hypothetical protein Cthe_2753 10 None None None 125972548 Common - pimeloyl-CoA synthesis (biotin biosynthesis) Cthe_0023 50 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 125975062 Common - iron-containing alcohol dehydrogenase Cthe_2579 172 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 125972569 Common - copper amine oxidase-like protein Cthe_0045 10 None None None 125975341 Nonpathogen - hypothetical protein Cthe_2859 1 None None None 125972674 Common - RNA modification enzyme, MiaB family Cthe_0150 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 125973925 Common - tryptophan synthase, alpha subunit Cthe_1411 217 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 125973308 Common - conserved hythetical protein Cthe_0790 38 None None None 125973726 Common - tryptophan synthase subunit beta Cthe_1211 224 COG1350 COG1350, Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB) General function prediction only 125975169 Common - thioesterase superfamily Cthe_2687 136 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 125973221 Nonpathogen - hypothetical protein Cthe_0703 2 None None None 125973682 Common - Radical SAM Cthe_1167 103 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 125973581 Common - DNA repair protein RecO Cthe_1066 85 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 125974276 Common - protein of unknown function DUF218 Cthe_1772 83 COG1434 COG1434, Uncharacterized conserved protein Function unknown 125973054 Nonpathogen - hypothetical protein Cthe_0535 1 None None None 125974553 Common - spore germination protein Cthe_2063 12 None None None 125972538 Nonpathogen - hypothetical protein Cthe_0013 1 None None None 125973985 Common - NADPH-dependent FMN reductase Cthe_1473 121 COG0431 COG0431, Predicted flavoprotein General function prediction only 125973281 Common - GTP-binding protein Cthe_0763 215 COG1161 COG1161, Predicted GTPases General function prediction only 125973954 Nonpathogen - hypothetical protein Cthe_1441 3 None None None 125975079 Common - protein tyrosine phosphatase Cthe_2596 114 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 125973108 Common - transposase IS3/IS911 Cthe_0590 39 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974947 Common - BRO-like protein Cthe_2462 42 COG3617 COG3617, Prophage antirepressor Transcription 125973200 Nonpathogen - hypothetical protein Cthe_0682 1 None None None 125973036 Common - IS66 Orf2 like Cthe_0516 50 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974600 Common - ABC transporter related protein Cthe_2110 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 125975160 Nonpathogen - hypothetical protein Cthe_2678 2 None None None 125972628 Common - riboflavin biosynthesis protein RibD Cthe_0104 231 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 125973504 Common - phosphoesterase, RecJ-like protein Cthe_0989 85 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 125974636 Common - integral membrane protein-like protein Cthe_2150 7 COG5542 COG5542, Predicted integral membrane protein Function unknown 125972678 Common - protein of unknown function DUF1292 Cthe_0154 16 None None None 125974160 Common - hypothetical protein Cthe_1654 4 None None None 125972661 Common - glyceraldehyde-3-phosphate dehydrogenase, type I Cthe_0137 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 125974228 Common - hypothetical protein Cthe_1724 10 None None None 125974656 Common - type III restriction enzyme, res subunit Cthe_2171 6 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 125973437 Common - transposase IS3/IS911 Cthe_0920 39 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974544 Nonpathogen - protein of unknown function DUF324 Cthe_2054 2 COG1337 COG1337, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 125972841 Common - hypothetical protein Cthe_0320 8 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 125972531 Nonpathogen - hypothetical protein Cthe_0006 1 None None None 125975474 Nonpathogen - hypothetical protein Cthe_2995 2 None None None 125974389 Common - phage integrase-like SAM-like Cthe_1885 84 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 125975218 Common - phosphoenolpyruvate-protein phosphotransferase Cthe_2736 226 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 125974988 Common - Cupin 2, conserved barrel Cthe_2503 18 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 125972816 Common - phosphoserine aminotransferase Cthe_0295 78 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 125973885 Nonpathogen - hypothetical protein Cthe_1370 1 None None None 125973836 Common - chaperone protein DnaJ Cthe_1321 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 125974079 Common - extracellular solute-binding protein, family 3 Cthe_1570 102 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 125973101 Common - PAS/PAC sensor signal transduction histidine kinase Cthe_0582 217 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 125975545 Common - ABC transporter related protein Cthe_3066 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 125975244 Nonpathogen - transcriptional regulator-like protein Cthe_2762 4 COG2378 COG2378, Predicted transcriptional regulator Transcription 125975547 Common - periplasmic sensor signal transduction histidine kinase Cthe_3068 221 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 125974533 Nonpathogen - hypothetical protein Cthe_2041 1 None None None 125974528 Common - serine/threonine protein kinase Cthe_2034 13 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 125973865 Common - single-strand binding protein Cthe_1350 214 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 125973586 Common - PhoH-like protein Cthe_1071 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 125975221 Common - trigger factor Cthe_2739 212 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 125975351 Common - protein of unknown function DUF21 Cthe_2870 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 125973752 Common leuS leucyl-tRNA synthetase Cthe_1237 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 125975506 Common - methylcitrate synthase Cthe_3027 191 COG0372 GltA, Citrate synthase Energy production and conversion 125973554 Common - ribosomal protein S20 Cthe_1039 202 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 125973420 Common - protein-export membrane protein SecF Cthe_0903 202 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 125973734 Common - hypothetical protein Cthe_1219 7 None None None 125975006 Common - putative RNA polymerase sigma factor SigI Cthe_2521 14 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 125974222 Nonpathogen - hypothetical protein Cthe_1718 1 None None None 125972833 Common - ATPase AAA-2 Cthe_0312 217 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 125973763 Common - phosphoribosylformylglycinamidine cyclo-ligase Cthe_1248 234 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 125973184 Common - HflC protein Cthe_0666 214 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 125975564 Common - response regulator receiver protein Cthe_3085 36 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 125972844 Nonpathogen - hypothetical protein Cthe_0323 1 None None None 125974140 Common - hypothetical protein Cthe_1634 24 None None None 125974229 Common - hypothetical protein Cthe_1725 2 None None None 125972949 Common - NADH dehydrogenase (ubiquinone), 24 kDa subunit Cthe_0428 156 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 125974381 Nonpathogen - hypothetical protein Cthe_1877 1 None None None 125975613 Nonpathogen - hypothetical protein Cthe_3135 2 None None None 125975413 Common - DNA-directed RNA polymerase, alpha subunit Cthe_2932 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 125973786 Common - Carbohydrate binding family 6 Cthe_1271 24 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 125975290 Common - transcriptional regulator, LacI family Cthe_2808 127 COG1609 PurR, Transcriptional regulators Transcription 125973427 Common - extracellular solute-binding protein, family 5 Cthe_0910 213 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 125974465 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Cthe_1964 249 COG3634 AhpF, Alkyl hydroperoxide reductase, large subunit Posttranslational modification, protein turnover, chaperones 125975128 Nonpathogen - hypothetical protein Cthe_2646 3 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 125973332 Common - DNA repair protein RecN Cthe_0814 227 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 125973846 Common aspS aspartyl-tRNA synthetase Cthe_1331 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 125974181 Common - transposase IS3/IS911 Cthe_1675 39 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974939 Common - Fibronectin, type III Cthe_2454 47 COG3401 COG3401, Fibronectin type 3 domain-containing protein General function prediction only 125975682 Common - CRISPR-associated helicase Cas3 Cthe_3204 83 COG1203 COG1203, Predicted helicases General function prediction only 125975437 Nonpathogen - hypothetical protein Cthe_2956 1 None None None 125975182 Nonpathogen - hypothetical protein Cthe_2700 4 None None None 125972800 Common - pseudouridine synthase Cthe_0278 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 125973972 Nonpathogen - hypothetical protein Cthe_1460 1 None None None 125974035 Nonpathogen - hypothetical protein Cthe_1524 3 None None None 125974475 Common - hypothetical protein Cthe_1974 3 None None None 125974336 Nonpathogen - hypothetical protein Cthe_1832 2 None None None 125972710 Common - UDP-glucose 4-epimerase Cthe_0186 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 125973226 Common - FAD dependent oxidoreductase Cthe_0708 142 COG2081 COG2081, Predicted flavoproteins General function prediction only 125973897 Common - Patatin Cthe_1382 14 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 125974923 Nonpathogen - hypothetical protein Cthe_2438 2 None None None 125973154 Nonpathogen - hypothetical protein Cthe_0636 1 None None None 125974312 Common - transposase IS116/IS110/IS902 Cthe_1808 111 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 125975555 Common - Radical SAM Cthe_3076 98 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 125974886 Common - protein of unknown function DUF1021 Cthe_2401 18 COG4466 Veg, Uncharacterized protein conserved in bacteria Function unknown 125972813 Common - protein of unknown function DUF255 Cthe_0291 105 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 125974263 Common - hypothetical protein Cthe_1759 14 None None None 125974871 Common - VanW Cthe_2386 38 COG2720 COG2720, Uncharacterized vancomycin resistance protein Defense mechanisms 125973695 Common - uncharacterized predicted metal-binding protein Cthe_1180 1 None None None 125974120 Common - glycosyl hydrolase-like protein Cthe_1613 19 COG3858 COG3858, Predicted glycosyl hydrolase General function prediction only 125975130 Common - sugar transferase Cthe_2648 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 125975105 Common - hypothetical protein Cthe_2622 25 COG3951 COG3951, Rod binding protein Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 125974448 Common - Redoxin Cthe_1947 180 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 125974437 Common - hypothetical protein Cthe_1936 14 COG4506 COG4506, Uncharacterized protein conserved in bacteria Function unknown 125972998 Common - flagellar motor switch protein FliM Cthe_0477 108 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 125974974 Common - Peptidoglycan-binding LysM Cthe_2489 77 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 125974059 Common - Methyltransferase type 12 Cthe_1549 67 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 125974127 Common - Protein of unknown function DUF132 Cthe_1620 16 COG1569 COG1569, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 125975430 Common - Pectinesterase Cthe_2949 21 COG4677 PemB, Pectin methylesterase Carbohydrate transport and metabolism 125975108 Common murC UDP-N-acetylmuramate--L-alanine ligase Cthe_2626 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 125974232 Common - DNA-cytosine methyltransferase Cthe_1728 119 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 125972902 Nonpathogen - hypothetical protein Cthe_0381 1 None None None 125972804 Common - glycogen/starch synthases, ADP-glucose type Cthe_0282 137 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 125973894 Common - oxidoreductase-like protein Cthe_1379 172 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 125972575 Common - hypothetical protein Cthe_0051 19 COG1306 COG1306, Uncharacterized conserved protein Function unknown 125975028 Common - Spore germination protein-like protein Cthe_2543 24 COG5401 COG5401, Spore germination protein General function prediction only 125972642 Common - anti-sigma-factor antagonist Cthe_0118 72 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 125973245 Common - cell envelope-related transcriptional attenuator Cthe_0727 63 COG1316 LytR, Transcriptional regulator Transcription 125973901 Common - hypothetical protein Cthe_1386 7 None None None 125972750 Nonpathogen - hypothetical protein Cthe_0228 1 None None None 125974732 Common - regulatory protein, MerR Cthe_2247 9 None None None 125974407 Common - glycosyl transferase, family 28 Cthe_1905 38 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 125973095 Common - Ribulose-phosphate 3-epimerase Cthe_0576 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 125974318 Common - Urease accessory protein UreF Cthe_1814 74 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 125973816 Common - protein of unknown function DUF795 Cthe_1301 28 COG1323 COG1323, Predicted nucleotidyltransferase General function prediction only 125975363 Common - Histidinol dehydrogenase Cthe_2882 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 125973544 Common - phosphate acetyltransferase Cthe_1029 158 COG0280 Pta, Phosphotransacetylase Energy production and conversion 125974708 Common - LmbE-like protein Cthe_2223 57 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 125974082 Common - nitrogenase iron protein Cthe_1573 80 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 125974752 Common - V-type ATP synthase subunit A Cthe_2267 247 COG1155 NtpA, Archaeal/vacuolar-type H+-ATPase subunit A Energy production and conversion 125974563 Common - amidohydrolase Cthe_2073 172 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 125972611 Common - maf protein Cthe_0087 194 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 125973646 Nonpathogen - hypothetical protein Cthe_1131 1 None None None 125973476 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase Cthe_0959 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 125972707 Common - protein of unknown function DUF208 Cthe_0183 67 COG1636 COG1636, Uncharacterized protein conserved in bacteria Function unknown 125974615 Common - binding-protein-dependent transport systems inner membrane component Cthe_2126 144 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 125972527 Common - hypothetical protein Cthe_0002 2 None None None 125974092 Common - deoxyribose-phosphate aldolase Cthe_1583 138 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 125975011 Common - precorrin-2 oxidase / ferrochelatase Cthe_2526 116 COG1648 CysG, Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) Coenzyme metabolism 125974362 Common - peptidase M23B Cthe_1858 220 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 125972829 Common - hypothetical protein Cthe_0308 2 None None None 125974599 Nonpathogen - copper amine oxidase-like protein Cthe_2109 27 COG4880 COG4880, Secreted protein containing C-terminal beta-propeller domain distantly related to WD-40 repeats General function prediction only 125973143 Common - glycoside hydrolase, family 9 Cthe_0625 18 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 125973523 Common - aminodeoxychorismate lyase Cthe_1008 184 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 125974072 Common - ABC transporter related protein Cthe_1563 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 125974759 Nonpathogen - hypothetical protein Cthe_2274 1 None None None 125974817 Common - multi-sensor signal transduction histidine kinase Cthe_2332 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 125975588 Common - UBA/THIF-type NAD/FAD binding fold Cthe_3110 218 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 125973168 Nonpathogen - hypothetical protein Cthe_0650 2 COG1428 COG1428, Deoxynucleoside kinases Nucleotide transport and metabolism 125974917 Common - electron transport complex, RnfABCDGE type, G subunit Cthe_2432 65 COG4659 RnfG, Predicted NADH:ubiquinone oxidoreductase, subunit RnfG Energy production and conversion 125975581 Common - 2-hydroxyglutaryl-CoA dehydratase, D-component Cthe_3103 14 COG1775 HgdB, Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB Amino acid transport and metabolism 125975021 Common - sulfate adenylyltransferase subunit 2 Cthe_2536 157 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 125975320 Common - conserved hypothetical protein precursor Cthe_2838 19 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 125974744 Common - hypothetical protein Cthe_2259 4 None None None 125973319 Common - transposase, mutator type Cthe_0801 89 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974724 Common - carbon storage regulator, CsrA Cthe_2239 63 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 125975269 Common - ferredoxin Cthe_2787 71 COG3894 COG3894, Uncharacterized metal-binding protein General function prediction only 125975485 Common - ErfK/YbiS/YcfS/YnhG Cthe_3006 138 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 125975700 Common - hypothetical protein Cthe_3222 3 None None None 125973532 Nonpathogen - hypothetical protein Cthe_1017 1 None None None 125973401 Common - Lytic transglycosylase, catalytic Cthe_0884 165 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 125973022 Nonpathogen - hypothetical protein Cthe_0502 1 None None None 125975260 Common - cytidyltransferase-related domain Cthe_2778 31 COG3172 NadR, Predicted ATPase/kinase involved in NAD metabolism Coenzyme metabolism 125974800 Common - DNA mismatch endonuclease vsr Cthe_2315 71 COG3727 Vsr, DNA G:T-mismatch repair endonuclease DNA replication, recombination, and repair 125974774 Nonpathogen - hypothetical protein Cthe_2289 1 None None None 125975577 Common - glycosyl transferase, family 2 Cthe_3099 198 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 125974547 Nonpathogen - CRISPR-associated protein, TM1812 family Cthe_2057 15 None None None 125973918 Common - GTP-binding protein, HSR1-related Cthe_1404 169 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 125974785 Nonpathogen - CRISPR-associated protein Cas5 Cthe_2300 3 COG1688 COG1688, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 125973288 Common - signal recognition particle protein Cthe_0770 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 125974087 Common - Radical SAM Cthe_1578 92 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 125974804 Common - restriction endonuclease (HaeIII) Cthe_2319 3 None None None 125974418 Common - two component transcriptional regulator, winged helix family Cthe_1916 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 125974845 Common - glycoside hydrolase, family 9 Cthe_2360 18 None None None 125974595 Common - DNA-directed DNA polymerase Cthe_2105 236 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 125975673 Common - hypothetical protein Cthe_3195 2 None None None 125975566 Common - response regulator receiver protein Cthe_3087 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 125975652 Common - hypothetical protein Cthe_3174 7 None None None 125974376 Common - Tn7-like transposition protein C Cthe_1872 26 None None None 125974051 Common - glutamyl-tRNA(Gln) amidotransferase, A subunit Cthe_1541 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 125974324 Common - ABC transporter related protein Cthe_1820 249 COG4674 COG4674, Uncharacterized ABC-type transport system, ATPase component General function prediction only 125975711 Nonpathogen - hypothetical protein Cthe_3233 1 None None None 125974080 Common - binding-protein-dependent transport systems inner membrane component Cthe_1571 168 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 125974953 Common - hypothetical protein Cthe_2468 2 None None None 125974634 Common - Carbohydrate-binding, CenC-like protein Cthe_2148 2 None None None 125975394 Common - ribosomal protein L14 Cthe_2913 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 125972878 Common - alpha-glucan phosphorylases Cthe_0357 150 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 125975186 Common - Transketolase-like protein Cthe_2704 225 COG3959 COG3959, Transketolase, N-terminal subunit Carbohydrate transport and metabolism 125974582 Common - dimethyladenosine transferase Cthe_2092 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 125974235 Common - HNH endonuclease Cthe_1731 39 COG1403 McrA, Restriction endonuclease Defense mechanisms 125975440 Nonpathogen - hypothetical protein Cthe_2960 1 None None None 125973030 Common - Integrase, catalytic region Cthe_0510 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 125974835 Common - cell wall hydrolase, SleB Cthe_2350 4 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 125973622 Common - type II secretion system protein E Cthe_1107 191 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 125973591 Common - protein of unknown function DUF881 Cthe_1076 25 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 125972898 Common - peptidase M56, BlaR1 Cthe_0377 28 COG4219 MecR1, Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component Transcription / Signal transduction mechanisms 125973360 Common - stage III sporulation protein AD Cthe_0842 15 None None None 125975089 Common - ATP synthase F1, alpha subunit Cthe_2606 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 125974994 Common - DNA topoisomerase Cthe_2509 226 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 125973415 Common - metal dependent phosphohydrolase Cthe_0898 124 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 125974536 Common - hypothetical protein Cthe_2046 3 None None None 125972535 Nonpathogen - hypothetical protein Cthe_0010 1 None None None 125972723 Common - 4Fe-4S ferredoxin, iron-sulfur binding Cthe_0199 150 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 125973115 Common - thiamine biosynthesis protein ThiS Cthe_0597 57 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 125974170 Common - transcriptional regulator, MerR family Cthe_1664 68 COG0789 SoxR, Predicted transcriptional regulators Transcription 125974268 Common - Outer membrane protein-like protein Cthe_1764 8 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 125974371 Common - carbamoyl-phosphate synthase, small subunit Cthe_1867 231 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 125975037 Common - Radical SAM Cthe_2553 76 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 125974830 Common - DegT/DnrJ/EryC1/StrS aminotransferase Cthe_2345 193 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 125974891 Common - hypothetical protein Cthe_2406 5 COG1406 COG1406, Predicted inhibitor of MCP methylation, homolog of CheC Cell motility and secretion 125974612 Nonpathogen - hypothetical protein Cthe_2122 1 None None None 125974064 Common - NLPA lipoprotein Cthe_1555 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 125972771 Common - peptidase C11, clostripain Cthe_0249 14 None None None 125975286 Common - ABC transporter related protein Cthe_2804 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 125975007 Common - membrane associated protein Cthe_2522 10 None None None 125973317 Common - two component transcriptional regulator, winged helix family Cthe_0799 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 125973194 Common - tyrosine recombinase XerD Cthe_0676 231 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 125975150 Nonpathogen - hypothetical protein Cthe_2668 3 None None None 125975705 Common - copper amine oxidase-like protein Cthe_3227 10 None None None 125973703 Common - protein of unknown function DUF990 Cthe_1188 34 COG3694 COG3694, ABC-type uncharacterized transport system, permease component General function prediction only 125972942 Common spoVFB dipicolinate synthase subunit B Cthe_0421 28 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 125974320 Common ureC urease subunit alpha Cthe_1816 96 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 125974179 Common - transposase IS3/IS911 Cthe_1673 39 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974028 Common - type I phosphodiesterase/nucleotide pyrophosphatase Cthe_1517 31 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 125975387 Common rplB 50S ribosomal protein L2 Cthe_2906 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 125974156 Common - DNA-directed DNA polymerase Cthe_1650 210 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 125973359 Common - mutants block sporulation after engulfment Cthe_0841 15 None None None 125975406 Common - methionine aminopeptidase, type I Cthe_2925 248 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 125973916 Common - iron (metal) dependent repressor, DtxR family Cthe_1402 96 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 125975678 Common alaS alanyl-tRNA synthetase Cthe_3200 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 125973630 Common - Tn7-like transposition protein C Cthe_1115 21 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 125973775 Common - 4-hydroxybenzoyl-CoA thioesterase Cthe_1260 93 COG0824 FcbC, Predicted thioesterase General function prediction only 125972836 Common - putative RNA polymerase sigma factor SigI Cthe_0315 14 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 125974153 Common - hypothetical protein Cthe_1647 18 COG4983 COG4983, Uncharacterized conserved protein Function unknown 125973279 Common - Ribonuclease H Cthe_0761 208 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 125974948 Nonpathogen - DNA binding domain, excisionase family Cthe_2463 5 None None None 125974810 Common - Recombinase Cthe_2325 50 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 125974430 Nonpathogen - hypothetical protein Cthe_1929 1 COG5185 HEC1, Protein involved in chromosome segregation, interacts with SMC proteins Cell division and chromosome partitioning 125974719 Common - hypothetical protein Cthe_2234 1 None None None 125972691 Nonpathogen - response regulator receiver protein Cthe_0167 4 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 125973574 Nonpathogen - hypothetical protein Cthe_1059 1 None None None 125974714 Common - N-acetylneuraminate synthase Cthe_2229 79 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 125973418 Common - pantoate--beta-alanine ligase Cthe_0901 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 125972587 Common - Rubredoxin-type Fe(Cys)4 protein Cthe_0063 15 COG1592 COG1592, Rubrerythrin Energy production and conversion 125974094 Common - signal transduction histidine kinase, LytS Cthe_1585 109 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 125973026 Common - pyruvate formate-lyase activating enzyme Cthe_0506 134 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 125972568 Common - cellulosome enzyme, dockerin type I Cthe_0044 17 COG5337 CotH, Spore coat assembly protein Cell envelope biogenesis, outer membrane 125975159 Common - histidine kinase Cthe_2677 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 125974521 Nonpathogen - hypothetical protein Cthe_2027 4 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 125974196 Common - Integrase, catalytic region Cthe_1691 153 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973369 Common - peptidase A24A-like protein Cthe_0852 128 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 125974426 Nonpathogen - hypothetical protein Cthe_1925 1 None None None 125975441 Common - extracellular solute-binding protein, family 5 Cthe_2961 211 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 125974404 Common - Pyridoxal-5'-phosphate-dependent enzyme, beta subunit Cthe_1902 16 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 125974619 Common - hypothetical protein Cthe_2131 19 COG3877 COG3877, Uncharacterized protein conserved in bacteria Function unknown 125972732 Common - single-stranded-DNA-specific exonuclease RecJ Cthe_0208 192 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 125973405 Nonpathogen - type IV pilus assembly PilZ Cthe_0888 1 None None None 125975163 Common - serine phosphatase Cthe_2681 41 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 125972909 Common - Alcohol dehydrogenase GroES-like protein Cthe_0388 212 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 125973045 Nonpathogen - hypothetical protein Cthe_0525 1 None None None 125973398 Common - diguanylate cyclase Cthe_0881 177 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 125973190 Common - pyrroline-5-carboxylate reductase Cthe_0672 218 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 125974391 Common - transposase IS3/IS911 Cthe_1887 39 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974146 Common - hypothetical protein Cthe_1640 8 None None None 125975300 Common - CheA signal transduction histidine kinases Cthe_2818 148 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 125973373 Common - branched-chain amino acid aminotransferase Cthe_0856 214 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 125975604 Common - NUDIX hydrolase Cthe_3126 130 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 125974024 Common - DNA adenine methylase Cthe_1513 100 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 125973255 Common - Phosphopantethiene-protein transferase Cthe_0737 62 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 125972696 Nonpathogen - hypothetical protein Cthe_0172 1 None None None 125974643 Nonpathogen - hypothetical protein Cthe_2157 1 None None None 125973968 Common - ABC transporter related protein Cthe_1456 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 125973233 Common - Adenosylmethionine decarboxylase Cthe_0715 75 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 125974677 Nonpathogen - hypothetical protein Cthe_2192 1 None None None 125974500 Common - Integrase, catalytic region Cthe_2000 153 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 125974609 Common - glycoside hydrolase, family 10 Cthe_2119 43 COG3693 XynA, Beta-1,4-xylanase Carbohydrate transport and metabolism 125973614 Nonpathogen - hypothetical protein Cthe_1099 1 None None None 125974662 Nonpathogen - hypothetical protein Cthe_2177 1 None None None 125973001 Common - hypothetical protein Cthe_0480 4 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 125975666 Common - copper amine oxidase-like protein Cthe_3188 15 None None None 125972950 Common - NADH dehydrogenase (quinone) Cthe_0429 176 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 125974696 Common - 3-isopropylmalate dehydratase large subunit Cthe_2211 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 125974676 Common - 1,4-alpha-glucan branching enzyme Cthe_2191 151 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 125975421 Common - transcriptional regulator, CarD family Cthe_2940 85 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 125974499 Common - Integrase, catalytic region Cthe_1999 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 125972921 Common - hypothetical protein Cthe_0400 21 None None None 125972599 Nonpathogen - hypothetical protein Cthe_0075 1 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 125973927 Nonpathogen - hypothetical protein Cthe_1413 1 None None None 125973011 Common - CheA signal transduction histidine kinases Cthe_0490 157 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 125973617 Nonpathogen - fimbrial assembly protein Cthe_1102 1 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 125974877 Common - pyruvate flavodoxin/ferredoxin oxidoreductase-like protein Cthe_2392 117 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 125973656 Nonpathogen - hypothetical protein Cthe_1141 1 None None None 125973719 Common - hypothetical protein Cthe_1204 71 COG2718 COG2718, Uncharacterized conserved protein Function unknown 125973128 Common - histidinol-phosphate aminotransferase Cthe_0610 238 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 125975502 Common - respiratory-chain NADH dehydrogenase, subunit 1 Cthe_3023 183 COG0650 HyfC, Formate hydrogenlyase subunit 4 Energy production and conversion 125972852 Common - hypothetical protein Cthe_0331 14 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 125973264 Nonpathogen - conserved hypothetical protein-signal peptide prediction Cthe_0746 3 None None None 125974542 Nonpathogen - hypothetical protein Cthe_2052 1 None None None 125973481 Common - amino acid-binding ACT Cthe_0964 34 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 125973804 Nonpathogen - hypothetical protein Cthe_1289 1 None None None 125974455 Nonpathogen - hypothetical protein Cthe_1954 1 None None None 125974515 Common - hypothetical protein Cthe_2020 17 None None None 125973167 Nonpathogen - hypothetical protein Cthe_0649 1 None None None 125972592 Common - Peptidylprolyl isomerase Cthe_0068 200 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 125974683 Common - transposase Cthe_2198 84 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973028 Nonpathogen - hypothetical protein Cthe_0508 1 None None None 125975637 Common - transcriptional regulator, GntR family Cthe_3159 132 COG1802 GntR, Transcriptional regulators Transcription 125973147 Common - type II secretion system protein E Cthe_0629 221 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 125974706 Common - DegT/DnrJ/EryC1/StrS aminotransferase Cthe_2221 197 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 125974793 Common - CheC-like protein Cthe_2308 27 COG1406 COG1406, Predicted inhibitor of MCP methylation, homolog of CheC Cell motility and secretion 125972930 Common - hypothetical protein Cthe_0409 35 COG3830 COG3830, ACT domain-containing protein Signal transduction mechanisms 125972635 Common - putative hydrolase Cthe_0111 86 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 125975628 Common - cobalamin biosynthesis protein CobD Cthe_3150 148 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 125972785 Nonpathogen - hypothetical protein Cthe_0263 1 None None None 125974963 Common - phage minor structural GP20 Cthe_2478 13 None None None 125975585 Common - Radical SAM Cthe_3107 172 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 125974069 Common - Pyridoxal-5'-phosphate-dependent enzyme, beta subunit Cthe_1560 228 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 125972659 Common - beta-ketoacyl synthase Cthe_0135 211 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 125973443 Common - signal recognition particle-docking protein FtsY Cthe_0926 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 125975195 Common - dihydroxy-acid dehydratase Cthe_2713 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 125975073 Common - glycoside hydrolase, family 10 Cthe_2590 37 COG3693 XynA, Beta-1,4-xylanase Carbohydrate transport and metabolism 125974369 Nonpathogen - type IV pilus assembly PilZ Cthe_1865 1 None None None 125973374 Common - protein of unknown function DUF107 Cthe_0857 12 COG1030 NfeD, Membrane-bound serine protease (ClpP class) Posttranslational modification, protein turnover, chaperones 125972937 Nonpathogen - hypothetical protein Cthe_0416 1 None None None 125974492 Common - transposase IS3/IS911 Cthe_1992 39 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 125975375 Nonpathogen - hypothetical protein Cthe_2894 3 None None None 125973212 Common - spermidine synthase Cthe_0694 130 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 125972855 Common - putative anti-sigma regulatory factor, serine/threonine protein kinase Cthe_0334 40 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 125974017 Common - metal dependent phosphohydrolase Cthe_1506 14 COG4905 COG4905, Predicted membrane protein Function unknown 125974853 Common - protein of unknown function DUF37 Cthe_2368 184 COG0759 COG0759, Uncharacterized conserved protein Function unknown 125974334 Nonpathogen - hypothetical protein Cthe_1830 1 None None None 125973350 Common - exodeoxyribonuclease VII, small subunit Cthe_0832 16 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 125973705 Common - hypothetical protein Cthe_1190 1 None None None 125974208 Common - toxin secretion/phage lysis holin Cthe_1704 12 COG4824 COG4824, Phage-related holin (Lysis protein) General function prediction only 125975122 Common - UDP-N-acetylglucosamine 2-epimerase Cthe_2640 120 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 125972739 Common pheT phenylalanyl-tRNA synthetase subunit beta Cthe_0215 249 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 125974888 Common ipk 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase Cthe_2403 188 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 125975049 Nonpathogen - hypothetical protein Cthe_2565 1 None None None 125974351 Common - two component transcriptional regulator, winged helix family Cthe_1847 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 125973495 Common - hypothetical protein Cthe_0980 3 None None None 125973005 Common - flagellar biosynthetic protein FlhB Cthe_0484 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 125972978 Common - hypothetical protein Cthe_0457 43 COG3304 COG3304, Predicted membrane protein Function unknown 125973529 Common - MutS2 family protein Cthe_1014 204 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 125972688 Common - protein of unknown function UPF0044 Cthe_0164 91 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 125972746 Nonpathogen - hypothetical protein Cthe_0222 1 None None None 125974848 Common - methyltransferase GidB Cthe_2363 203 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 125974343 Common - biotin synthase Cthe_1839 67 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 125973464 Common - dihydroorotate dehydrogenase family protein Cthe_0947 229 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 125972552 Common - uncharacterized protein, YcgL-like protein Cthe_0028 10 COG3541 COG3541, Predicted nucleotidyltransferase General function prediction only 125973767 Common - Auxin Efflux Carrier Cthe_1252 108 COG0679 COG0679, Predicted permeases General function prediction only 125974697 Common - transcriptional regulator, AraC family Cthe_2212 149 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 125973778 Common - transcription attenuation protein MtrB Cthe_1263 11 None None None 125974824 Common - glycosyl transferase, group 1 Cthe_2339 42 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 125973857 Common - beta-lactamase-like protein Cthe_1342 222 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 125975147 Common - Zn-finger containing protein Cthe_2665 3 None None None 125975538 Common - phosphotransferase KptA/Tpt1 Cthe_3059 44 COG1859 KptA, RNA:NAD 2'-phosphotransferase Translation, ribosomal structure and biogenesis 125974286 Common rpsI 30S ribosomal protein S9 Cthe_1782 248 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 125975199 Common rpmG 50S ribosomal protein L33 Cthe_2717 86 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 125975636 Common - aconitate hydratase Cthe_3158 223 COG1048 AcnA, Aconitase A Energy production and conversion 125974968 Common - hypothetical protein Cthe_2483 3 None None None 125972667 Common - Phosphopyruvate hydratase Cthe_0143 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 125975318 Nonpathogen - hypothetical protein Cthe_2836 1 None None None 125974200 Common - Radical SAM Cthe_1695 170 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 125973306 Common - DivIVA Cthe_0788 34 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 125974110 Common - phosphate uptake regulator, PhoU Cthe_1601 197 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 125975115 Common - hypothetical protein Cthe_2633 18 None None None 125973098 Common - nitroreductase Cthe_0579 65 COG0778 NfnB, Nitroreductase Energy production and conversion 125975431 Common - Pectate lyase/Amb allergen Cthe_2950 25 COG3866 PelB, Pectate lyase Carbohydrate transport and metabolism 125975092 Common - ATP synthase F1, epsilon subunit Cthe_2609 44 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 125974048 Common - transcriptional regulator, XRE family Cthe_1538 23 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 125975273 Common - binding-protein-dependent transport systems inner membrane component Cthe_2791 141 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 125974950 Common - hypothetical protein Cthe_2465 7 None None None 125974209 Nonpathogen - hypothetical protein Cthe_1705 1 None None None 125973867 Common - UDP-glucose 6-dehydrogenase Cthe_1352 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 125975038 Common - glycosyl transferase, group 1 Cthe_2554 4 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 125973430 Common - transposase IS116/IS110/IS902 Cthe_0913 111 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 125975242 Common - glycoside hydrolase, family 9 Cthe_2760 16 None None None 125973171 Common - putative transcriptional regulator, CopG family Cthe_0653 14 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 125975233 Nonpathogen - hypothetical protein Cthe_2751 3 None None None 125972550 Common - adenosylmethionine-8-amino-7-oxononanoate aminotransferase Cthe_0025 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 125974841 Common - quinolinate synthetase complex, A subunit Cthe_2356 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 125975513 Nonpathogen - hypothetical protein Cthe_3034 2 None None None 125974100 Nonpathogen - hypothetical protein Cthe_1591 1 None None None 125975031 Nonpathogen - hypothetical protein Cthe_2547 1 None None None 125975040 Common - Radical SAM Cthe_2556 95 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 125975540 Nonpathogen - transcriptional repressor, CopY family Cthe_3061 1 COG3682 COG3682, Predicted transcriptional regulator Transcription 125973103 Common - protein of unknown function DUF503 Cthe_0584 38 COG1550 COG1550, Uncharacterized protein conserved in bacteria Function unknown 125974339 Nonpathogen - Viral A-type inclusion protein repeat containing protein Cthe_1835 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 125973859 Common - (p)ppGpp synthetase I, SpoT/RelA Cthe_1344 208 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 125972685 Common - protein of unknown function DUF464 Cthe_0161 19 COG2868 COG2868, Predicted ribosomal protein Translation, ribosomal structure and biogenesis 125973838 Common - GrpE protein Cthe_1323 232 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 125972602 Common - hypothetical protein Cthe_0078 14 None None None 125974226 Common - phage Terminase Cthe_1722 58 COG4626 COG4626, Phage terminase-like protein, large subunit General function prediction only 125972916 Common - RbsD or FucU transport Cthe_0395 42 COG1869 RbsD, ABC-type ribose transport system, auxiliary component Carbohydrate transport and metabolism 125975216 Common - VanW Cthe_2734 34 COG2720 COG2720, Uncharacterized vancomycin resistance protein Defense mechanisms 125974941 Nonpathogen - nuclease Cthe_2456 6 None None None 125974522 Nonpathogen - hypothetical protein Cthe_2028 1 None None None 125973556 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase Cthe_1041 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 125973383 Common - pyruvate flavodoxin/ferredoxin oxidoreductase-like protein Cthe_0866 126 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 125974001 Nonpathogen - hypothetical protein Cthe_1489 1 None None None 125974183 Common - Abortive infection protein Cthe_1677 7 None None None 125975683 Nonpathogen - hypothetical protein Cthe_3205 5 None None None 125973761 Common - phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase Cthe_1246 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 125973534 Common - binding-protein-dependent transport systems inner membrane component Cthe_1019 177 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 125974306 Common - cobalt ABC transporter, inner membrane subunit CbiQ Cthe_1802 56 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 125975090 Common - F0F1 ATP synthase subunit gamma Cthe_2607 206 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 125975416 Common - methyltransferase small Cthe_2935 127 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 125974919 Common - electron transport complex, RnfABCDGE type, A subunit Cthe_2434 76 COG4657 RnfA, Predicted NADH:ubiquinone oxidoreductase, subunit RnfA Energy production and conversion 125973243 Common - response regulator receiver modulated metal dependent phosphohydrolase Cthe_0725 160 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 125973425 Common - pseudouridine synthase, RluA family Cthe_0908 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 125974761 Common - AAA ATPase, central region Cthe_2276 249 COG1222 RPT1, ATP-dependent 26S proteasome regulatory subunit Posttranslational modification, protein turnover, chaperones 125973207 Nonpathogen - RDD domain containing protein Cthe_0689 2 None None None 125972968 Common - sporulation sigma factor SigE Cthe_0447 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 125973844 Common - putative CoA-substrate-specific enzyme activase Cthe_1329 65 COG3581 COG3581, Uncharacterized protein conserved in bacteria Function unknown 125975549 Common - protein of unknown function DUF1256 Cthe_3070 14 None None None 125975472 Nonpathogen - hypothetical protein Cthe_2993 1 None None None 125973439 Common - diaminopimelate dehydrogenase Cthe_0922 16 COG1712 COG1712, Predicted dinucleotide-utilizing enzyme General function prediction only 125972947 Common - putative PAS/PAC sensor protein Cthe_0426 27 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 125973959 Common - peptidase S1 and S6, chymotrypsin/Hap Cthe_1446 221 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 125975299 Common - CheW protein Cthe_2817 139 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 125974484 Common - transposase IS116/IS110/IS902 Cthe_1983 72 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973506 Common - translation initiation factor IF-2 Cthe_0991 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 125975207 Common - DNA-directed RNA polymerase subunit beta' Cthe_2725 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 125975398 Common - ribosomal protein S8 Cthe_2917 248 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 125973514 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase Cthe_0999 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 125973697 Common - protein of unknown function DUF58 Cthe_1182 6 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 125975675 Common - PRC-barrel domain protein Cthe_3197 13 COG3881 COG3881, Uncharacterized protein conserved in bacteria Function unknown 125973165 Common - anaerobic ribonucleoside-triphosphate reductase activating protein Cthe_0647 105 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 125974416 Common - TPR repeat domain containing protein Cthe_1914 2 None None None 125972984 Common - flagellar basal-body rod protein FlgC Cthe_0463 126 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 125974086 Common - hypothetical protein Cthe_1577 14 None None None 125974898 Common - NLP/P60 Cthe_2413 156 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 125973929 Common - ABC transporter related protein Cthe_1415 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 125973612 Common - peptidase S14, ClpP Cthe_1097 22 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 125973823 Common - pyruvate phosphate dikinase Cthe_1308 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 125974414 Common - copper amine oxidase-like protein Cthe_1912 11 None None None 125975167 Common - putative TIM-barrel protein, nifR3 family Cthe_2685 213 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 125973997 Common - beta-lactamase-like protein Cthe_1485 83 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 125973066 Common - periplasmic solute binding protein Cthe_0547 186 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 125973731 Common - ATP-dependent Clp protease adaptor protein ClpS Cthe_1216 119 COG2127 COG2127, Uncharacterized conserved protein Function unknown 125973806 Common - amidohydrolase 2 Cthe_1291 47 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 125973453 Common - 3-oxoacyl-(acyl-carrier-protein) synthase III Cthe_0936 225 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 125974147 Common - HNH endonuclease Cthe_1641 21 COG1403 McrA, Restriction endonuclease Defense mechanisms 125975447 Common - major facilitator superfamily MFS_1 Cthe_2967 53 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 125973667 Nonpathogen - hypothetical protein Cthe_1152 1 None None None 125974991 Common - S-layer-like domain containing protein Cthe_2506 48 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 125974117 Common - hypothetical protein Cthe_1610 6 None None None 125973056 Common - two component transcriptional regulator, winged helix family Cthe_0537 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 125975141 Common - YabP-like protein Cthe_2659 15 None None None 125973909 Common - two component transcriptional regulator, winged helix family Cthe_1394 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 125973186 Common - spore germination protein Cthe_0668 10 None None None 125973488 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Cthe_0973 208 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 125972793 Common - type 3a, cellulose-binding Cthe_0271 8 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 125975455 Common - putative RNA polymerase sigma factor SigI Cthe_2975 14 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 125975479 Common - phosphate transporter Cthe_3000 164 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 125973783 Common - histidine kinase Cthe_1268 149 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 125975353 Common - glycoside hydrolase, family 5 Cthe_2872 18 COG2730 BglC, Endoglucanase Carbohydrate transport and metabolism 125973313 Common - alpha amylase, catalytic region Cthe_0795 172 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 125973073 Common - phosphoribosylformylglycinamidine synthase Cthe_0554 233 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 125974791 Common - MATE efflux family protein Cthe_2306 188 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 125973728 Nonpathogen - hypothetical protein Cthe_1213 1 None None None 125973952 Nonpathogen - hypothetical protein Cthe_1439 3 None None None 125974070 Common - hypothetical protein Cthe_1561 5 None None None 125973441 Common - hypothetical protein Cthe_0924 5 None None None 125974931 Common - ABC-type sugar transport system periplasmic component-like protein Cthe_2446 88 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 125974558 Common - 8-oxoguanine DNA glycosylase-like protein Cthe_2068 32 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 125974015 Common - Linocin_M18 bacteriocin protein Cthe_1504 23 COG1659 COG1659, Uncharacterized protein, linocin/CFP29 homolog Function unknown 125974109 Common - two component transcriptional regulator, winged helix family Cthe_1600 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 125973571 Common - transglutaminase-like protein Cthe_1056 105 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 125975018 Common - sulfate ABC transporter, inner membrane subunit CysW Cthe_2533 182 COG4208 CysW, ABC-type sulfate transport system, permease component Inorganic ion transport and metabolism 125974551 Common - hypothetical protein Cthe_2061 39 COG1939 COG1939, Uncharacterized protein conserved in bacteria Function unknown 125975255 Common - Integrase, catalytic region Cthe_2773 153 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 125973880 Nonpathogen - hypothetical protein Cthe_1365 1 None None None 125974588 Common - nucleoside recognition Cthe_2098 39 COG0700 SpmB, Uncharacterized membrane protein Function unknown 125973818 Common - glycosyl transferase, group 1 Cthe_1303 235 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 125974329 Common - multi-sensor hybrid histidine kinase Cthe_1825 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 125973029 Common - sodium ion-translocating decarboxylase, beta subunit Cthe_0509 56 COG1883 OadB, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit Energy production and conversion 125974597 Common - thymidylate kinase Cthe_2107 31 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 125974750 Common - V-type ATP synthase subunit C Cthe_2265 27 COG1527 NtpC, Archaeal/vacuolar-type H+-ATPase subunit C Energy production and conversion 125974768 Common - methyl-accepting chemotaxis sensory transducer Cthe_2283 181 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 125973542 Common - protein of unknown function DUF177 Cthe_1027 47 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 125973795 Nonpathogen - hypothetical protein Cthe_1280 2 None None None 125974815 Nonpathogen - hypothetical protein Cthe_2330 1 None None None 125973113 Common - hypothetical protein Cthe_0595 5 None None None 125974757 Common - hypothetical protein Cthe_2272 33 COG3580 COG3580, Uncharacterized protein conserved in bacteria Function unknown 125973363 Common - stage III sporulation protein spoIIIAA Cthe_0845 32 COG3854 SpoIIIAA, ncharacterized protein conserved in bacteria Function unknown 125975568 Common - fumarate hydratase Cthe_3090 148 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 125974316 Common - Urease accessory protein UreD Cthe_1812 66 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 125974806 Nonpathogen - hypothetical protein Cthe_2321 5 None None None 125974726 Common - hypothetical protein Cthe_2241 8 None None None 125974626 Common - alpha-L-arabinofuranosidase B Cthe_2139 11 COG5520 COG5520, O-Glycosyl hydrolase Cell envelope biogenesis, outer membrane 125973330 Common - response regulator receiver protein Cthe_0812 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 125975060 Common - adenylate cyclase Cthe_2577 47 COG2954 COG2954, Uncharacterized protein conserved in bacteria Function unknown 125975641 Nonpathogen - Carbohydrate binding family 25 Cthe_3163 5 None None None 125972640 Common - protein of unknown function DUF199 Cthe_0116 54 COG1481 COG1481, Uncharacterized protein conserved in bacteria Function unknown 125973937 Common - protein of unknown function UPF0118 Cthe_1423 127 COG0628 PerM, Predicted permease General function prediction only 125973944 Nonpathogen - hypothetical protein Cthe_1430 1 None None None 125974030 Common - putative RNA methylase Cthe_1519 139 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 125975267 Common - methyltransferase MtaA/CmuA family Cthe_2785 145 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 125975570 Common - conserved hypothetical protein, CF-27 family Cthe_3092 13 None None None 125974905 Common - HD superfamily phosphohydrolases-like protein Cthe_2420 82 COG1078 COG1078, HD superfamily phosphohydrolases General function prediction only 125972718 Nonpathogen - hypothetical protein Cthe_0194 1 None None None 125973152 Common - serine/threonine protein kinase Cthe_0634 141 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 125974937 Common - oligoendopeptidase F Cthe_2452 87 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 125974802 Common - response regulator receiver protein Cthe_2317 5 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 125973380 Common - glutamine synthetase, catalytic region Cthe_0863 119 COG3968 COG3968, Uncharacterized protein related to glutamine synthetase General function prediction only 125975454 Common - hypothetical protein Cthe_2974 2 COG5373 COG5373, Predicted membrane protein Function unknown 125972613 Common - rod shape-determining protein MreC Cthe_0089 123 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 125974783 Common - CRISPR-associated protein Cas4 Cthe_2298 35 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 125974099 Common - peptidase M56, BlaR1 Cthe_1590 22 COG4219 MecR1, Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component Transcription / Signal transduction mechanisms 125975082 Common - CMP/dCMP deaminase, zinc-binding Cthe_2599 92 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 125975591 Common - Nucleotidyl transferase Cthe_3113 239 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 125974746 Nonpathogen - hypothetical protein Cthe_2261 1 None None None 125973474 Common - preprotein translocase, YajC subunit Cthe_0957 3 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 125973342 Common - copper amine oxidase-like protein Cthe_0824 11 None None None 125974776 Nonpathogen - hypothetical protein Cthe_2291 1 None None None 125975382 Common - putative anti-sigma regulatory factor, serine/threonine protein kinase Cthe_2901 23 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 125974330 Common - response regulator receiver sensor signal transduction histidine kinase Cthe_1826 225 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 125972904 Common - protein of unknown function DUF214 Cthe_0383 1 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 125973986 Nonpathogen - hypothetical protein Cthe_1474 4 None None None 125973899 Common - FolC bifunctional protein Cthe_1384 218 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 125974135 Common - phage major capsid protein, HK97 family Cthe_1628 61 COG4653 COG4653, Predicted phage phi-C31 gp36 major capsid-like protein General function prediction only 125973974 Common - transcriptional regulator, XRE family Cthe_1462 22 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 125973662 Common - hypothetical protein Cthe_1147 31 None None None 125973871 Common - glycosyltransferase Cthe_1356 18 None None None 125974184 Common - hypothetical protein Cthe_1678 162 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 125974435 Common - Abortive infection protein Cthe_1934 13 None None None 125974249 Common - transcriptional regulator, XRE family Cthe_1745 13 COG1396 HipB, Predicted transcriptional regulators Transcription 125974584 Nonpathogen - hypothetical protein Cthe_2094 1 None None None 125974866 Common - seryl-tRNA synthetase Cthe_2381 245 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 125973830 Common - Guanylate kinase Cthe_1315 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 125975074 Nonpathogen - hypothetical protein Cthe_2591 1 None None None 125972765 Common - copper amine oxidase-like protein Cthe_0243 19 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 125975612 Nonpathogen - hypothetical protein Cthe_3134 2 None None None 125974242 Nonpathogen - hypothetical protein Cthe_1738 5 None None None 125974126 Common - transcriptional regulator, AbrB family Cthe_1619 4 None None None 125975484 Common - Peptidoglycan-binding LysM Cthe_3005 67 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 125972893 Common - glutamate synthase (NADPH), homotetrameric Cthe_0372 193 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 125975103 Common - protein of unknown function DUF1078-like protein Cthe_2620 125 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 125973684 Common - Beta-lactamase class A-like protein Cthe_1169 51 COG2367 PenP, Beta-lactamase class A Defense mechanisms 125973564 Common - regulatory protein RecX Cthe_1049 51 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 125972700 Nonpathogen - hypothetical protein Cthe_0176 1 None None None 125973172 Common thiH thiamine biosynthesis protein ThiH Cthe_0654 65 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 125973141 Common - transcriptional regulators, TraR/DksA family Cthe_0623 122 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 125973919 Common - Spore coat assembly protein-like protein Cthe_1405 15 COG5337 CotH, Spore coat assembly protein Cell envelope biogenesis, outer membrane 125973674 Common - hypothetical protein Cthe_1159 8 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 125973497 Common - MraZ protein Cthe_0982 138 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 125974730 Nonpathogen - hypothetical protein Cthe_2245 7 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 125974364 Common - cell division ATP-binding protein FtsE Cthe_1860 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 125974463 Common - pseudouridine synthase, RluA family Cthe_1962 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 125974873 Nonpathogen - hypothetical protein Cthe_2388 2 None None None 125974274 Nonpathogen - hypothetical protein Cthe_1770 1 None None None 125972806 Common - protein of unknown function DUF815 Cthe_0284 90 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 125974654 Common - metallophosphoesterase Cthe_2169 105 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 125972802 Common - Coat F Cthe_0280 2 COG5577 COG5577, Spore coat protein Cell envelope biogenesis, outer membrane 125975380 Common - putative anti-sigma regulatory factor, serine/threonine protein kinase Cthe_2899 10 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 125975332 Common - transposase IS116/IS110/IS902 Cthe_2850 72 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 125972639 Common - glycogen debranching enzyme, putative Cthe_0115 42 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 125974409 Common - amino acid adenylation domain Cthe_1907 223 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism