Polaromonas naphthalenivorans CJ2, complete genome NC_008781 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 121603840 Common - Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) Pnap_0931 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 121604831 Nonpathogen - TolA protein Pnap_1929 1 None None None 121604797 Common - intracellular protease, PfpI family Pnap_1895 162 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 121604279 Common - phosphoesterase, PA-phosphatase related Pnap_1372 9 None None None 121603236 Common - S-adenosylmethionine--tRNA-ribosyltransferase-isomerase Pnap_0321 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 121604001 Common - amidophosphoribosyltransferase Pnap_1092 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 121603649 Common - preprotein translocase subunit SecA Pnap_0738 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 121603977 Common - aminopeptidase N Pnap_1068 156 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 121603074 Nonpathogen - hypothetical protein Pnap_0157 1 None None None 121602965 Common - periplasmic binding protein/LacI transcriptional regulator Pnap_0047 125 COG1609 PurR, Transcriptional regulators Transcription 121606746 Common - putative transcriptional regulators, CopG/Arc/MetJ family Pnap_3858 15 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 121604959 Common - hypothetical protein Pnap_2058 42 COG3530 COG3530, Uncharacterized protein conserved in bacteria Function unknown 121604978 Nonpathogen - HNH endonuclease Pnap_2077 14 COG1403 McrA, Restriction endonuclease Defense mechanisms 121606476 Nonpathogen - hypothetical protein Pnap_3588 1 None None None 121604878 Common - CbbQ/NirQ/NorQ C-terminal domain protein Pnap_1977 95 COG0714 COG0714, MoxR-like ATPases General function prediction only 121604198 Common - Alcohol dehydrogenase, zinc-binding domain protein Pnap_1291 170 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 121605076 Common - ATP-dependent helicase HrpA Pnap_2176 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 121606690 Common - transcriptional regulator, LysR family Pnap_3802 153 COG0583 LysR, Transcriptional regulator Transcription 121605375 Common - dihydrodipicolinate synthetase Pnap_2479 202 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 121604952 Common - glycosyl transferase, family 2 Pnap_2051 61 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 121604078 Common - N-acetylmuramoyl-L-alanine amidase Pnap_1170 166 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 121606771 Common - protein of unknown function DUF1631 Pnap_3883 19 None None None 121606898 Common - filamentous haemagglutinin family outer membrane protein Pnap_4014 57 None None None 121605044 Common - transcriptional regulator, LysR family Pnap_2144 184 COG0583 LysR, Transcriptional regulator Transcription 121604205 Common - secretion protein HlyD Pnap_1298 150 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 121604339 Common - NADH-ubiquinone/plastoquinone oxidoreductase, chain 6 Pnap_1433 66 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 121603211 Common - transcriptional regulator, LysR family Pnap_0296 145 COG0583 LysR, Transcriptional regulator Transcription 121605528 Common - transcriptional regulator, Fis family Pnap_2634 210 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 121603208 Common - FAD linked oxidase domain protein Pnap_0293 200 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 121606091 Common - ribonuclease BN Pnap_3201 35 COG1295 Rbn, Predicted membrane protein Function unknown 121604406 Common - Polyprenyl synthetase Pnap_1500 242 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 121605810 Common - NusB antitermination factor Pnap_2919 149 COG0781 NusB, Transcription termination factor Transcription 121606267 Common - glucosyltransferase MdoH Pnap_3378 55 COG2943 MdoH, Membrane glycosyltransferase Cell envelope biogenesis, outer membrane 121605918 Common - bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase Pnap_3027 215 COG1049 AcnB, Aconitase B Energy production and conversion 121605550 Common - multi-sensor signal transduction histidine kinase Pnap_2656 221 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 121605775 Common - glutamate racemase Pnap_2884 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 121603890 Common - translation initiation factor IF-1 Pnap_0981 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 121604816 Common - enoyl-CoA hydratase Pnap_1914 177 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 121604971 Common - Alcohol dehydrogenase GroES domain protein Pnap_2070 202 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 121604411 Common - selenophosphate synthetase Pnap_1505 141 COG0709 SelD, Selenophosphate synthase Amino acid transport and metabolism 121605537 Common - phage integrase family protein Pnap_2643 101 COG0582 XerC, Integrase DNA replication, recombination, and repair 121605995 Common - AAA ATPase Pnap_3104 41 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 121603434 Common - HipA domain protein Pnap_0521 67 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 121603662 Common - ribosomal protein L21 Pnap_0751 215 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 121604556 Common - Extracellular ligand-binding receptor Pnap_1650 153 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 121604236 Common - hypothetical protein Pnap_1329 19 COG4309 COG4309, Uncharacterized conserved protein Function unknown 121605431 Common - polyhydroxyalkonate synthesis repressor, PhaR Pnap_2536 65 COG5394 COG5394, Uncharacterized protein conserved in bacteria Function unknown 121605840 Common - alpha/beta hydrolase fold Pnap_2949 48 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 121605628 Common - Extradiol ring-cleavage dioxygenase LigAB, LigA subunit Pnap_2734 15 None None None 121606387 Common - glycosyl transferase, family 39 Pnap_3498 27 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 121604386 Common - NAD-dependent epimerase/dehydratase Pnap_1480 2 None None None 121606083 Common - undecaprenyl diphosphate synthase Pnap_3193 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 121605942 Common - hypothetical protein Pnap_3051 3 None None None 121606974 Common - putative transcriptional regulator, MerR family Pnap_4091 143 COG0789 SoxR, Predicted transcriptional regulators Transcription 121606990 Common - KpsF/GutQ family protein Pnap_4108 161 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 121604691 Common - ABC-type transport system ipermease component Pnap_1789 14 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 121606697 Common - L-carnitine dehydratase/bile acid-inducible protein F Pnap_3809 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 121605848 Common - ATP-dependent Clp protease, proteolytic subunit ClpP Pnap_2957 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 121606418 Common - extracellular ligand-binding receptor Pnap_3529 93 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 121603594 Common - Glutamate synthase (ferredoxin) Pnap_0683 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 121606959 Common - Organic solvent tolerance protein Pnap_4076 108 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 121602976 Nonpathogen - hypothetical protein Pnap_0058 1 None None None 121603914 Common - cyanophycin synthetase Pnap_1005 73 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 121603491 Common - binding-protein-dependent transport systems inner membrane component Pnap_0579 185 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 121604620 Common - putative transmembrane protein Pnap_1715 12 None None None 121603241 Common - 4-hydroxybenzoate polyprenyl transferase Pnap_0326 153 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 121603981 Common - MCP methyltransferase, CheR-type Pnap_1072 140 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 121605209 Common - Chromate transporter Pnap_2309 32 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 121604514 Nonpathogen - hypothetical protein Pnap_1608 1 None None None 121604125 Common - protein of unknown function DUF58 Pnap_1218 38 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 121605946 Common - protein of unknown function DUF45 Pnap_3055 38 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 121603899 Common - protein of unknown function DUF107 Pnap_0990 73 COG1030 NfeD, Membrane-bound serine protease (ClpP class) Posttranslational modification, protein turnover, chaperones 121604717 Common - ZipA, C-terminal FtsZ-binding region Pnap_1815 20 None None None 121604727 Nonpathogen - hypothetical protein Pnap_1825 3 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 121604493 Common - ferredoxin Pnap_1587 72 COG3894 COG3894, Uncharacterized metal-binding protein General function prediction only 121603196 Common - alanine racemase domain protein Pnap_0280 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 121603795 Common - cytochrome oxidase assembly Pnap_0886 45 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 121604252 Common - DNA polymerase, beta-like region Pnap_1345 8 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 121604286 Common - Inositol-phosphate phosphatase Pnap_1380 208 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 121604875 Common - nickel-dependent hydrogenase, large subunit Pnap_1974 108 COG0374 HyaB, Ni,Fe-hydrogenase I large subunit Energy production and conversion 121604024 Common - short-chain dehydrogenase/reductase SDR Pnap_1116 231 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 121604398 Common - polar amino acid ABC transporter, inner membrane subunit Pnap_1492 163 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 121604191 Common - alpha/beta hydrolase fold Pnap_1284 14 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 121603589 Common - Shikimate kinase Pnap_0678 195 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 121604290 Common - protein of unknown function DUF615 Pnap_1384 59 COG3028 COG3028, Uncharacterized protein conserved in bacteria Function unknown 121603404 Common - 5,10-methylenetetrahydrofolate reductase Pnap_0491 146 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 121604447 Common - transcriptional regulator, LysR family Pnap_1541 116 COG0583 LysR, Transcriptional regulator Transcription 121605811 Common - aminotransferase Pnap_2920 236 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 121603088 Common - glutamyl-tRNA(Gln) amidotransferase, A subunit Pnap_0171 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 121603297 Nonpathogen - hypothetical protein Pnap_0382 2 None None None 121604280 Common - polysaccharide deacetylase Pnap_1373 112 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 121603264 Common - sodium/hydrogen exchanger Pnap_0349 23 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 121604682 Common - multi-sensor signal transduction histidine kinase Pnap_1780 219 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 121606005 Common - hypothetical protein Pnap_3115 20 None None None 121604082 Common - tyrosine recombinase XerD Pnap_1174 227 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 121605175 Common - parB-like partition proteins Pnap_2275 180 COG1475 Spo0J, Predicted transcriptional regulators Transcription 121605513 Nonpathogen - hypothetical protein Pnap_2619 1 None None None 121603642 Common - pyrroloquinoline quinone biosynthesis protein PqqC Pnap_0731 34 COG5424 COG5424, Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C Coenzyme metabolism 121604393 Common - Xylose isomerase domain protein TIM barrel Pnap_1487 15 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 121605515 Common - 3'-5' exonuclease Pnap_2621 14 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 121606627 Common - ATPase associated with various cellular activities, AAA_5 Pnap_3739 68 COG0714 COG0714, MoxR-like ATPases General function prediction only 121605976 Common - pseudouridine synthase, RluA family Pnap_3085 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 121604588 Common - peptidase S8 and S53, subtilisin, kexin, sedolisin Pnap_1683 34 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 121605403 Nonpathogen - hypothetical protein Pnap_2507 1 None None None 121606376 Common - polysaccharide biosynthesis protein Pnap_3487 48 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 121603194 Common - twitching motility protein Pnap_0278 221 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 121606725 Nonpathogen - hypothetical protein Pnap_3837 3 None None None 121606625 Common - zinc finger, SWIM domain protein Pnap_3737 15 None None None 121606630 Common - VWA containing CoxE family protein Pnap_3742 25 COG2425 COG2425, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 121603465 Common - Acyl-CoA dehydrogenase, type 2, C-terminal domain Pnap_0553 81 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 121603518 Common - helix-turn-helix- domain containing protein, AraC type Pnap_0607 26 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 121605931 Common leuD isopropylmalate isomerase small subunit Pnap_3040 209 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 121603876 Nonpathogen - hypothetical protein Pnap_0967 1 None None None 121604939 Nonpathogen - hypothetical protein Pnap_2038 11 None None None 121603247 Common rplE 50S ribosomal protein L5 Pnap_0332 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 121605704 Nonpathogen - hypothetical protein Pnap_2810 1 None None None 121603856 Common - Triphosphoribosyl-dephospho-CoA synthase Pnap_0947 41 COG1767 CitG, Triphosphoribosyl-dephospho-CoA synthetase Coenzyme metabolism 121605352 Common - Cupin 2, conserved barrel domain protein Pnap_2454 30 COG3435 COG3435, Gentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 121606014 Common - imidazole glycerol phosphate synthase, glutamine amidotransferase subunit Pnap_3124 215 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 121605504 Common - dihydropteroate synthase Pnap_2610 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 121603775 Common - 3-oxoacid CoA-transferase, B subunit Pnap_0866 92 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 121606104 Common - ribosomal protein L28 Pnap_3214 173 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 121604838 Common - Saccharopine dehydrogenase Pnap_1936 33 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 121606565 Common - putative molecular chaperone protein HspA/DnaK Pnap_3677 129 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 121606803 Common - hypothetical protein Pnap_3915 19 None None None 121604211 Common - nitric oxide dioxygenase Pnap_1304 130 COG1017 Hmp, Hemoglobin-like flavoprotein Energy production and conversion 121605216 Common - putative ferredoxin like protein; FixX Pnap_2316 37 COG2440 FixX, Ferredoxin-like protein Energy production and conversion 121606861 Common - hypothetical protein Pnap_3974 82 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 121606273 Common - N-acetyl-anhydromuranmyl-L-alanine amidase Pnap_3384 107 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 121605396 Common - hypothetical protein Pnap_2500 19 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 121602957 Common - ABC transporter related Pnap_0039 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 121603908 Common - inner-membrane translocator Pnap_0999 150 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 121606944 Common - putative signal-transduction protein with CBS domains Pnap_4061 121 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 121606880 Common - response regulator receiver protein Pnap_3994 18 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 121604259 Nonpathogen - hypothetical protein Pnap_1352 2 None None None 121604687 Common - hypothetical protein Pnap_1785 8 None None None 121604458 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pnap_1552 4 None None None 121606113 Common - protein of unknown function DUF480 Pnap_3223 41 COG3132 COG3132, Uncharacterized protein conserved in bacteria Function unknown 121606639 Common - gamma-glutamyl phosphate reductase Pnap_3751 192 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 121603916 Common - ABC transporter related Pnap_1007 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 121605685 Nonpathogen - hypothetical protein Pnap_2791 3 None None None 121606468 Common - cytochrome B561 Pnap_3580 83 COG3038 CybB, Cytochrome B561 Energy production and conversion 121605228 Common - F0F1 ATP synthase subunit alpha Pnap_2329 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 121604364 Common - secreted hydrolase-like protein Pnap_1458 51 COG5621 COG5621, Predicted secreted hydrolase General function prediction only 121604342 Common - proton-translocating NADH-quinone oxidoreductase, chain M Pnap_1436 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 121605746 Common - translation initiation factor IF-3 Pnap_2853 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 121605416 Common - transposase IS66 Pnap_2521 66 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 121605421 Nonpathogen - hypothetical protein Pnap_2526 1 None None None 121606923 Common - ABC-type sugar transport system periplasmic component-like protein Pnap_4040 47 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 121604263 Common - putative undecaprenol kinase Pnap_1356 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 121604096 Common - 17 kDa surface antigen Pnap_1189 7 COG3133 SlyB, Outer membrane lipoprotein Cell envelope biogenesis, outer membrane 121606846 Common - integral membrane sensor signal transduction histidine kinase Pnap_3959 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121605801 Common - type IV pilus modification protein PilV Pnap_2910 18 COG4967 PilV, Tfp pilus assembly protein PilV Cell motility and secretion / Intracellular trafficking and secretion 121606516 Common - two component transcriptional regulator, LuxR family Pnap_3628 196 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 121604595 Common - extracellular ligand-binding receptor Pnap_1690 40 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 121606211 Common - hypothetical protein Pnap_3322 7 None None None 121602936 Nonpathogen - hypothetical protein Pnap_0018 2 None None None 121606452 Common - hypothetical protein Pnap_3564 23 None None None 121606483 Common - pseudouridine synthase Pnap_3595 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 121607003 Common - phospho-2-dehydro-3-deoxyheptonate aldolase Pnap_4121 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 121604629 Common - arginyl-tRNA-protein transferase Pnap_1724 85 COG2935 COG2935, Putative arginyl-tRNA:protein arginylyltransferase Posttranslational modification, protein turnover, chaperones 121604465 Common - 3-dehydroquinate dehydratase Pnap_1559 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 121602950 Nonpathogen - protein of unknown function DUF1328 Pnap_0032 1 None None None 121603841 Common - Cupin 2, conserved barrel domain protein Pnap_0932 18 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 121606589 Common argS arginyl-tRNA synthetase Pnap_3701 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 121605122 Common - putative addiction module antidote Pnap_2222 20 None None None 121606819 Nonpathogen - hypothetical protein Pnap_3931 3 None None None 121605093 Common - UvrD/REP helicase Pnap_2193 171 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 121605836 Common - anaerobic benzoate catabolism transcriptional regulator Pnap_2945 139 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 121603543 Common - hypothetical protein Pnap_0632 8 None None None 121604350 Common - RND efflux system, outer membrane lipoprotein, NodT family Pnap_1444 115 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 121605597 Common - NIPSNAP family containing protein Pnap_2703 10 None None None 121605156 Nonpathogen - hypothetical protein Pnap_2256 1 COG5566 COG5566, Uncharacterized conserved protein Function unknown 121606702 Common - CitB domain protein Pnap_3814 18 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 121604349 Common - transcriptional regulator, MarR family Pnap_1443 122 COG1846 MarR, Transcriptional regulators Transcription 121605887 Common - transposase Pnap_2996 15 None None None 121603386 Common - DinB family protein Pnap_0472 30 COG2318 DinB, Uncharacterized protein conserved in bacteria Function unknown 121603041 Common - protein of unknown function DUF1275 Pnap_0124 16 COG3619 COG3619, Predicted membrane protein Function unknown 121603534 Common - DNA/RNA endonuclease G NUC1-like protein Pnap_0623 18 COG1864 NUC1, DNA/RNA endonuclease G, NUC1 Nucleotide transport and metabolism 121606500 Common - ABC transporter related Pnap_3612 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 121606401 Common - regulatory protein, LuxR Pnap_3512 24 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 121606285 Common - DnaJ domain protein Pnap_3396 8 None None None 121603742 Common - cytoplasmic chaperone TorD family protein Pnap_0833 26 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 121606816 Common - Resolvase, N-terminal domain Pnap_3928 108 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 121604862 Common - hydrogenase assembly chaperone hypC/hupF Pnap_1961 93 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 121606730 Common - putative outer membrane protein Pnap_3842 5 None None None 121605342 Common - hypothetical protein Pnap_2443 29 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 121605952 Common - Ribonuclease III Pnap_3061 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 121604055 Common - protein of unknown function DUF214 Pnap_1147 28 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 121602992 Common - hypothetical protein Pnap_0074 2 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 121605114 Nonpathogen - hypothetical protein Pnap_2214 1 None None None 121605142 Common - hypothetical protein Pnap_2242 11 None None None 121606576 Common - aldo/keto reductase Pnap_3688 185 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 121605251 Common - putative regulatory protein, FmdB family Pnap_2352 15 COG2331 COG2331, Uncharacterized protein conserved in bacteria Function unknown 121603218 Common - hypothetical protein Pnap_0303 5 None None None 121603806 Common - peptidyl-tRNA hydrolase Pnap_0897 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 121606965 Common - Uncharacterized protein UPF0065 Pnap_4082 76 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121604151 Common - DEAD/DEAH box helicase domain protein Pnap_1244 234 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 121605966 Common - BNR/Asp-box repeat protein Pnap_3075 28 COG4692 COG4692, Predicted neuraminidase (sialidase) Carbohydrate transport and metabolism 121606330 Common - beta-lactamase domain protein Pnap_3441 107 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 121604915 Common - ABC transporter related Pnap_2014 249 COG4172 COG4172, ABC-type uncharacterized transport system, duplicated ATPase component General function prediction only 121604634 Common - phosphoribosylamine--glycine ligase Pnap_1729 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 121605387 Nonpathogen - hypothetical protein Pnap_2491 1 None None None 121603626 Common - cytochrome c1 Pnap_0715 63 COG2857 CYT1, Cytochrome c1 Energy production and conversion 121604416 Common - ABC transporter related Pnap_1510 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 121606497 Common - inner-membrane translocator Pnap_3609 146 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 121603985 Common - aldo/keto reductase Pnap_1076 192 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 121605104 Common pstA phosphate transporter permease subunit Pnap_2204 224 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 121605873 Common - protein of unknown function DUF1504 Pnap_2982 16 None None None 121605891 Common - major facilitator superfamily MFS_1 Pnap_3000 166 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 121606446 Common - filamentation induced by cAMP protein Fic Pnap_3558 23 COG3177 COG3177, Uncharacterized conserved protein Function unknown 121606983 Common - methionine biosynthesis protein MetW Pnap_4101 80 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 121602969 Nonpathogen - thiamineS protein Pnap_0051 13 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 121603324 Common - transposase, IS4 Pnap_0409 6 None None None 121604561 Common - 4-hydroxyphenylpyruvate dioxygenase Pnap_1655 48 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 121605625 Common - transcriptional regulator, GntR family Pnap_2731 133 COG1802 GntR, Transcriptional regulators Transcription 121604487 Common - hypothetical protein Pnap_1581 6 None None None 121606363 Common - acetyl-CoA acetyltransferase Pnap_3474 181 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 121603474 Common - cysteine synthase A Pnap_0562 215 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 121605186 Common hscA chaperone protein HscA Pnap_2286 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 121606327 Common - Uncharacterized protein UPF0065 Pnap_3438 72 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121606523 Nonpathogen - hypothetical protein Pnap_3635 3 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 121606759 Common - two component transcriptional regulator, winged helix family Pnap_3871 204 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 121604330 Common - NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Pnap_1424 162 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 121605658 Common - transposase, IS605 OrfB family Pnap_2764 77 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 121604187 Common - NADH dehydrogenase Pnap_1280 155 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 121604723 Common - phosphoribosylformylglycinamidine synthase Pnap_1821 232 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 121605489 Common - RND efflux system, outer membrane lipoprotein, NodT family Pnap_2594 106 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 121603226 Common - hypothetical protein Pnap_0311 11 COG4727 COG4727, Uncharacterized protein conserved in bacteria Function unknown 121606782 Common - response regulator receiver protein Pnap_3894 180 COG4566 TtrR, Response regulator Signal transduction mechanisms 121603268 Common - acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase Pnap_0353 210 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 121603952 Nonpathogen - hypothetical protein Pnap_1043 5 None None None 121606905 Common - dihydropyrimidinase Pnap_4021 183 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 121605532 Common - ApbE family lipoprotein Pnap_2638 136 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 121602983 Common - Lysine exporter protein (LYSE/YGGA) Pnap_0065 104 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 121603025 Nonpathogen - hypothetical protein Pnap_0108 1 None None None 121605340 Nonpathogen - hypothetical protein Pnap_2441 1 None None None 121605282 Common - methylmalonyl-CoA mutase Pnap_2383 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 121606201 Common - phage tail E family protein Pnap_3311 16 None None None 121606023 Common - polysaccharide export protein Pnap_3133 121 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 121603656 Common - prolyl-tRNA synthetase Pnap_0745 247 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 121604477 Common - GCN5-related N-acetyltransferase Pnap_1571 44 COG3153 COG3153, Predicted acetyltransferase General function prediction only 121606595 Common - glycosyl transferase, family 2 Pnap_3707 46 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 121602943 Common - glycosyl transferase, family 51 Pnap_0025 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 121605261 Common - ABC transporter related Pnap_2362 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 121605755 Common - putative aminotransferase Pnap_2863 236 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 121605655 Common - protein of unknown function DUF1446 Pnap_2761 36 None None None 121605284 Common - hypothetical protein Pnap_2385 71 COG2719 SpoVR, Uncharacterized conserved protein Function unknown 121606650 Common - nitrate/nitrite antiporter Pnap_3762 81 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 121605631 Common - hypothetical protein Pnap_2737 7 COG4849 COG4849, Uncharacterized protein conserved in bacteria Function unknown 121606614 Common - Methyltransferase type 12 Pnap_3726 14 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 121606352 Common - thioesterase superfamily protein Pnap_3463 135 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 121605716 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Pnap_2822 82 COG0348 NapH, Polyferredoxin Energy production and conversion 121605768 Common - dihydroxy-acid dehydratase Pnap_2877 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 121606255 Common - Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family Pnap_3366 120 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 121606432 Common - phosphoesterase, PA-phosphatase related Pnap_3543 82 None None None 121603808 Common - ribose-phosphate pyrophosphokinase Pnap_0899 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 121603516 Common - enoyl-CoA hydratase Pnap_0605 144 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 121604133 Common - 2-nitropropane dioxygenase, NPD Pnap_1226 77 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 121604803 Common - 4-hydroxybenzoate 3-monooxygenase Pnap_1901 68 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 121603717 Common - acyl-CoA dehydrogenase domain protein Pnap_0806 149 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 121605033 Common - electron transfer flavoprotein, alpha subunit Pnap_2132 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 121603371 Common aceK bifunctional isocitrate dehydrogenase kinase/phosphatase protein Pnap_0457 29 COG4579 COG4579, Isocitrate dehydrogenase kinase/phosphatase Signal transduction mechanisms 121605029 Common - Enoyl-CoA hydratase/isomerase Pnap_2128 184 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 121604107 Common - Lytic transglycosylase, catalytic Pnap_1200 182 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 121606054 Common queF 7-cyano-7-deazaguanine reductase Pnap_3164 94 COG2904 COG2904, Uncharacterized protein conserved in bacteria Function unknown 121605154 Common - phage portal protein, lambda family Pnap_2254 37 COG5511 COG5511, Bacteriophage capsid protein General function prediction only 121605613 Common - NAD-dependent epimerase/dehydratase Pnap_2719 234 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 121604856 Common - NADH ubiquinone oxidoreductase, 20 kDa subunit Pnap_1955 77 COG1740 HyaA, Ni,Fe-hydrogenase I small subunit Energy production and conversion 121603262 Nonpathogen - hypothetical protein Pnap_0347 3 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 121604500 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Pnap_1594 18 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 121606169 Common - CsbD family protein Pnap_3279 27 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 121604272 Common - protein of unknown function DUF893, YccS/YhfK Pnap_1365 48 COG1289 COG1289, Predicted membrane protein Function unknown 121603875 Nonpathogen - hypothetical protein Pnap_0966 1 None None None 121606568 Common - isocitrate dehydrogenase, NADP-dependent Pnap_3680 65 COG2838 Icd, Monomeric isocitrate dehydrogenase Energy production and conversion 121603751 Common - fumarylacetoacetate (FAA) hydrolase Pnap_0842 178 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 121605950 Common - DNA repair protein RecO Pnap_3059 75 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 121606124 Common - hypothetical protein Pnap_3234 3 None None None 121604881 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Pnap_1980 98 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 121603061 Common - fimbrial biogenesis outer membrane usher protein Pnap_0144 39 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 121604277 Common - hypothetical protein Pnap_1370 14 None None None 121604382 Common - homoserine kinase Pnap_1476 64 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 121603059 Nonpathogen - hypothetical protein Pnap_0142 3 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 121605350 Common - maleylacetoacetate isomerase Pnap_2452 104 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 121603930 Common - Uncharacterized protein UPF0065 Pnap_1021 75 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121603399 Common - hypothetical protein Pnap_0486 4 None None None 121604519 Common - histone deacetylase superfamily Pnap_1613 161 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 121603498 Common - CcmE/CycJ protein Pnap_0586 97 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 121603035 Common - hypothetical protein Pnap_0118 15 COG3391 COG3391, Uncharacterized conserved protein Function unknown 121606558 Common - spermidine synthase-like protein Pnap_3670 55 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 121606199 Common - phage major tail tube protein Pnap_3309 29 COG3498 COG3498, Phage tail tube protein FII General function prediction only 121606450 Common - D-alanyl-D-alanine dipeptidase Pnap_3562 56 COG2173 DdpX, D-alanyl-D-alanine dipeptidase Cell envelope biogenesis, outer membrane 121606826 Nonpathogen - hypothetical protein Pnap_3938 1 None None None 121603274 Common - PAS/PAC sensor signal transduction histidine kinase Pnap_0359 219 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 121603652 Common - NUDIX hydrolase Pnap_0741 167 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 121606495 Common - AMP-dependent synthetase and ligase Pnap_3607 203 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 121603883 Common ureC urease subunit alpha Pnap_0974 96 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 121603687 Common - Shikimate/quinate 5-dehydrogenase Pnap_0776 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 121603313 Common - response regulator receiver protein Pnap_0398 10 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 121605771 Common - acetate--CoA ligase Pnap_2880 214 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 121606332 Common - transcriptional regulator, LysR family Pnap_3443 129 COG0583 LysR, Transcriptional regulator Transcription 121606262 Common - tRNA-i(6)A37 thiotransferase enzyme MiaB Pnap_3373 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 121603568 Common groEL chaperonin GroEL Pnap_0657 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 121604644 Common - conserved hypothetical transposase Pnap_1740 14 None None None 121605377 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pnap_2481 28 None None None 121605127 Common - molybdopterin converting factor, subunit 1 Pnap_2227 29 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 121606234 Common pyrB aspartate carbamoyltransferase catalytic subunit Pnap_3345 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 121603816 Common - DNA repair protein RecN Pnap_0907 203 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 121604094 Common - phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase Pnap_1186 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 121604103 Common - dihydrodipicolinate synthase Pnap_1196 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 121606035 Common - Cupin 2, conserved barrel domain protein Pnap_3145 30 COG3435 COG3435, Gentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 121604641 Common - glycosyl transferase, group 1 Pnap_1737 140 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 121603758 Common - MORN repeat-containing protein Pnap_0849 26 COG4642 COG4642, Uncharacterized protein conserved in bacteria Function unknown 121604986 Nonpathogen - peptidase C14, caspase catalytic subunit p20 Pnap_2085 16 None None None 121604138 Common - RNA-binding S4 domain protein Pnap_1231 119 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 121605798 Common - Glycine hydroxymethyltransferase Pnap_2907 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 121606859 Nonpathogen - hypothetical protein Pnap_3972 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 121604966 Common - glycosyl transferase, family 51 Pnap_2065 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 121604651 Common - transposase, IS4 family protein Pnap_1749 31 None None None 121604270 Nonpathogen - hypothetical protein Pnap_1363 4 None None None 121606003 Nonpathogen - hypothetical protein Pnap_3112 1 None None None 121604299 Common - ISXo7 transposase Pnap_1393 39 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 121605082 Common - hypothetical protein Pnap_2182 10 None None None 121606649 Common - nitrate reductase, alpha subunit Pnap_3761 103 COG5013 NarG, Nitrate reductase alpha subunit Energy production and conversion 121603734 Common - transcriptional regulator, LysR family Pnap_0823 173 COG0583 LysR, Transcriptional regulator Transcription 121606852 Common - biotin--acetyl-CoA-carboxylase ligase Pnap_3965 212 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 121606275 Common - ribonucleotide-diphosphate reductase subunit beta Pnap_3386 162 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 121603601 Common - anti-sigma-factor antagonist (STAS) domain protein Pnap_0690 10 COG3113 COG3113, Predicted NTP binding protein (contains STAS domain) General function prediction only 121606540 Common - glutamine amidotransferase of anthranilate synthase Pnap_3652 238 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 121603828 Common - hypothetical protein Pnap_0919 3 COG4575 ElaB, Uncharacterized conserved protein Function unknown 121603710 Common - 4-hydroxybenzoyl-CoA thioesterase Pnap_0799 15 COG0824 FcbC, Predicted thioesterase General function prediction only 121606218 Nonpathogen - hypothetical protein Pnap_3329 1 None None None 121606079 Common - polysaccharide biosynthesis protein Pnap_3189 52 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 121606640 Common - hypothetical protein Pnap_3752 20 None None None 121605557 Common - Uncharacterized protein UPF0065 Pnap_2663 65 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121606711 Common - hypothetical protein Pnap_3823 8 None None None 121605434 Common - 3-hydroxybutyrate dehydrogenase Pnap_2539 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 121606632 Common - FMN-binding negative transcriptional regulator Pnap_3744 60 COG2808 PaiB, Transcriptional regulator Transcription 121603962 Common - integral membrane protein Pnap_1053 36 COG5473 COG5473, Predicted integral membrane protein Function unknown 121605711 Common - NUDIX hydrolase Pnap_2817 77 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 121602985 Common - protein of unknown function DUF1234 Pnap_0067 54 COG3545 COG3545, Predicted esterase of the alpha/beta hydrolase fold General function prediction only 121605242 Common - nitrogenase molybdenum-iron protein beta chain Pnap_2343 54 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 121606158 Common - ABC transporter related Pnap_3268 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 121605398 Common - Conjugal transfer TrbD family protein Pnap_2502 28 COG5268 TrbD, Type IV secretory pathway, TrbD component Cell motility and secretion / Intracellular trafficking and secretion 121604314 Nonpathogen - hypothetical protein Pnap_1408 1 None None None 121604170 Nonpathogen - hypothetical protein Pnap_1263 1 None None None 121603022 Common - two component transcriptional regulator, LuxR family Pnap_0105 153 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 121606048 Nonpathogen - hypothetical protein Pnap_3158 1 None None None 121605691 Common - integration host factor, beta subunit Pnap_2797 176 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 121603349 Common - putative lipase transmembrane protein Pnap_0435 22 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 121605720 Common - regulatory protein, ArsR Pnap_2826 136 COG0640 ArsR, Predicted transcriptional regulators Transcription 121603959 Common - integral membrane protein Pnap_1050 37 COG5473 COG5473, Predicted integral membrane protein Function unknown 121604045 Nonpathogen - hypothetical protein Pnap_1137 1 None None None 121603394 Common - cyclic nucleotide-binding protein Pnap_0480 64 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 121605235 Common - F0F1 ATP synthase subunit beta Pnap_2336 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 121603556 Common - OsmC family protein Pnap_0645 86 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 121606190 Common - phage baseplate assembly protein V Pnap_3300 33 COG4540 gpV, Phage P2 baseplate assembly protein gpV General function prediction only 121603422 Common - PhoH family protein Pnap_0509 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 121603007 Common - protein of unknown function DUF6, transmembrane Pnap_0090 26 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 121604144 Common - Uncharacterized protein UPF0065 Pnap_1237 69 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121605133 Common - protein of unknown function DUF498 Pnap_2233 38 COG3737 COG3737, Uncharacterized conserved protein Function unknown 121606160 Common - binding-protein-dependent transport systems inner membrane component Pnap_3270 158 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 121605787 Common - peptidyl-prolyl cis-trans isomerase, cyclophilin type Pnap_2896 197 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 121604902 Common - inosine-5'-monophosphate dehydrogenase Pnap_2001 240 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 121603121 Common rplD 50S ribosomal protein L4 Pnap_0204 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 121606547 Common - hypothetical protein Pnap_3659 16 COG5591 COG5591, Uncharacterized conserved protein Function unknown 121603522 Common - Carotenoid oxygenase Pnap_0611 36 COG3670 COG3670, Lignostilbene-alpha,beta-dioxygenase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 121603072 Common - hypothetical protein Pnap_0155 4 None None None 121606459 Common purT phosphoribosylglycinamide formyltransferase 2 Pnap_3571 200 COG0027 PurT, Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Nucleotide transport and metabolism 121604991 Common - hypothetical protein Pnap_2090 63 COG1432 COG1432, Uncharacterized conserved protein Function unknown 121605744 Common rplT 50S ribosomal protein L20 Pnap_2851 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 121606718 Common - binding-protein-dependent transport systems inner membrane component Pnap_3830 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 121606588 Common - PsiF repeat protein Pnap_3700 22 None None None 121606439 Nonpathogen - hypothetical protein Pnap_3551 1 None None None 121604893 Common - putative signal peptide protein Pnap_1992 6 None None None 121605724 Common - type I secretion outer membrane protein, TolC family Pnap_2830 109 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 121606222 Common - phage transcriptional regulator, AlpA Pnap_3333 3 COG3311 AlpA, Predicted transcriptional regulator Transcription 121605957 Common - putative sigma E regulatory protein, MucB/RseB Pnap_3066 48 COG3026 RseB, Negative regulator of sigma E activity Signal transduction mechanisms 121605881 Common - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase Pnap_2990 183 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 121606876 Common - transcriptional regulator, LysR family Pnap_3990 151 COG0583 LysR, Transcriptional regulator Transcription 121604460 Common - L-carnitine dehydratase/bile acid-inducible protein F Pnap_1554 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 121603536 Common - hypothetical protein Pnap_0625 2 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 121605544 Nonpathogen - hypothetical protein Pnap_2650 1 None None None 121603545 Common - hypothetical protein Pnap_0634 58 COG2187 COG2187, Uncharacterized protein conserved in bacteria Function unknown 121603105 Common - Carboxymethylenebutenolidase Pnap_0188 98 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 121603524 Common - transposase, IS605 OrfB family Pnap_0613 78 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 121603409 Common - protein of unknown function DUF519 Pnap_0496 84 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 121605069 Common - Leucyl aminopeptidase Pnap_2169 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 121606722 Common - helix-turn-helix- domain containing protein, AraC type Pnap_3834 89 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 121606179 Common - protein of unknown function DUF264 Pnap_3289 27 COG5484 COG5484, Uncharacterized conserved protein Function unknown 121605987 Common - response regulator receiver protein Pnap_3096 161 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 121603577 Common - cytochrome c assembly protein Pnap_0666 84 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 121605327 Common - Uncharacterised conserved protein UCP030820 Pnap_2428 53 COG3749 COG3749, Uncharacterized protein conserved in bacteria Function unknown 121605858 Common - acriflavin resistance protein Pnap_2967 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 121604994 Common - putative transcriptional regulator, GntR family Pnap_2093 221 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 121606030 Common - AAA ATPase, central domain protein Pnap_3140 158 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 121603810 Common - putative lipoprotein Pnap_0901 12 COG3017 LolB, Outer membrane lipoprotein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 121603306 Common - UspA domain protein Pnap_0391 110 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 121605974 Common - Rieske (2Fe-2S) domain protein Pnap_3083 36 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 121603560 Common - porin, Gram-negative type Pnap_0649 26 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 121604948 Common - UBA/THIF-type NAD/FAD binding protein Pnap_2047 89 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 121604704 Common - hypothetical protein Pnap_1802 28 COG5579 COG5579, Uncharacterized conserved protein Function unknown 121606067 Nonpathogen - hypothetical protein Pnap_3177 1 None None None 121604660 Common - ribosomal protein S2 Pnap_1758 228 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 121606170 Common - two component transcriptional regulator, winged helix family Pnap_3280 218 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 121604821 Common - Asparaginase Pnap_1919 130 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 121605455 Common - FMN-dependent alpha-hydroxy acid dehydrogenase Pnap_2560 117 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 121604162 Common - Isoprenylcysteine carboxyl methyltransferase Pnap_1255 37 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 121604604 Nonpathogen - HNH endonuclease Pnap_1699 12 COG1403 McrA, Restriction endonuclease Defense mechanisms 121603529 Common - 5-carboxymethyl-2-hydroxymuconate delta-isomerase Pnap_0618 178 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 121604113 Common - protein of unknown function DUF404 Pnap_1206 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 121605861 Common - two component transcriptional regulator, winged helix family Pnap_2970 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 121602927 Common - septum site-determining protein MinC Pnap_0009 99 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 121605309 Nonpathogen - NHL repeat containing protein Pnap_2410 1 None None None 121604757 Nonpathogen - hypothetical protein Pnap_1855 1 None None None 121603906 Common - twin-arginine translocation pathway signal Pnap_0997 114 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 121605047 Common - aminotransferase, class I and II Pnap_2147 128 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 121603638 Nonpathogen - hypothetical protein Pnap_0727 1 None None None 121604926 Common - aldo/keto reductase Pnap_2025 190 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 121606663 Common - putative transcriptional regulator, Crp/Fnr family Pnap_3775 131 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 121603453 Common - putative transposase Pnap_0541 35 COG5659 COG5659, FOG: Transposase DNA replication, recombination, and repair 121605499 Common - ABC transporter related Pnap_2605 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 121606882 Common - 3-dehydroquinate dehydratase Pnap_3996 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 121606985 Common - protein of unknown function UPF0016 Pnap_4103 62 COG2119 COG2119, Predicted membrane protein Function unknown 121605037 Common - beta-ketoadipyl CoA thiolase Pnap_2136 174 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 121604733 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Pnap_1831 159 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 121606364 Common - hypothetical protein Pnap_3475 12 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 121604474 Common - scaffold protein Pnap_1568 146 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 121604614 Common - NAD+ synthetase Pnap_1709 220 COG0171 NadE, NAD synthase Coenzyme metabolism 121606675 Common - Biopolymer transport protein ExbD/TolR Pnap_3787 141 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 121603344 Common - transposase IS3/IS911 family protein Pnap_0430 35 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 121603281 Nonpathogen - hypothetical protein Pnap_0366 1 None None None 121604768 Common - putative transcriptional regulator Pnap_1866 147 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 121605294 Common - ribosomal protein S6 Pnap_2395 188 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 121605096 Common rho transcription termination factor Rho Pnap_2196 221 COG1158 Rho, Transcription termination factor Transcription 121604957 Common - polar amino acid ABC transporter, inner membrane subunit Pnap_2056 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 121604598 Common - response regulator receiver protein Pnap_1693 220 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 121604950 Common - OmpA domain protein Pnap_2049 148 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 121605007 Common - putative transcriptional regulator, GntR family Pnap_2106 156 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 121603156 Common - phosphoenolpyruvate-protein phosphotransferase Pnap_0239 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 121604712 Common - succinyl-diaminopimelate desuccinylase Pnap_1810 204 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 121605075 Nonpathogen - hypothetical protein Pnap_2175 1 None None None 121606229 Common - Smr protein/MutS2 Pnap_3340 97 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 121605676 Common - putative transmembrane protein Pnap_2782 17 None None None 121606765 Common - methionyl-tRNA formyltransferase Pnap_3877 215 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 121604921 Common - Lysine decarboxylase Pnap_2020 86 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 121604788 Nonpathogen - hypothetical protein Pnap_1886 1 None None None 121605207 Common - 3-oxoacyl-(acyl-carrier-protein) reductase Pnap_2307 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 121603187 Common - Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase Pnap_0270 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 121606300 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase Pnap_3411 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 121605332 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Pnap_2433 216 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 121604157 Common - TRAP transporter solute receptor, TAXI family Pnap_1250 50 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 121606341 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Pnap_3452 12 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 121606049 Common - DNA-directed DNA polymerase Pnap_3159 181 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 121603142 Common - hypothetical protein Pnap_0225 4 None None None 121604578 Common - hypothetical protein Pnap_1673 72 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 121606269 Common - cytochrome c assembly protein Pnap_3380 103 COG4137 COG4137, ABC-type uncharacterized transport system, permease component General function prediction only 121606538 Common - anthranilate phosphoribosyltransferase Pnap_3650 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 121603182 Common - Uncharacterized protein UPF0065 Pnap_0265 73 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121606932 Common - multi-sensor signal transduction histidine kinase Pnap_4049 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 121606601 Nonpathogen - hypothetical protein Pnap_3713 2 None None None 121603289 Common - putative lipoprotein Pnap_0374 12 None None None 121602979 Nonpathogen - prevent-host-death family protein Pnap_0061 5 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 121604220 Common - hypothetical protein Pnap_1313 5 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 121604667 Common - putative membrane-associated zinc metalloprotease Pnap_1765 203 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 121603256 Common - ribosomal protein L36 Pnap_0341 135 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 121604292 Common - hypothetical protein Pnap_1386 18 None None None 121606147 Common - hypothetical protein Pnap_3257 25 COG4255 COG4255, Uncharacterized protein conserved in bacteria Function unknown 121603934 Common - hypothetical protein Pnap_1025 46 COG2346 COG2346, Truncated hemoglobins General function prediction only 121604619 Common - putative transmembrane protein Pnap_1714 19 None None None 121604761 Common - AFG1-family ATPase Pnap_1859 104 COG1485 COG1485, Predicted ATPase General function prediction only 121606474 Common - Peptidoglycan-binding domain 1 protein Pnap_3586 74 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 121605661 Common - FAD linked oxidase domain protein Pnap_2767 102 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 121606891 Common - cytosine deaminase Pnap_4007 78 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 121603995 Common - 17 kDa surface antigen Pnap_1086 5 COG3134 COG3134, Predicted outer membrane lipoprotein Function unknown 121606915 Common - dethiobiotin synthase Pnap_4031 157 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 121603675 Common - general secretion pathway protein G Pnap_0764 73 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 121605313 Nonpathogen - hypothetical protein Pnap_2414 1 None None None 121606206 Common - putative transcriptional regulator, XRE family Pnap_3316 16 COG1396 HipB, Predicted transcriptional regulators Transcription 121603098 Common - transcriptional regulator, LysR family Pnap_0181 146 COG0583 LysR, Transcriptional regulator Transcription 121603201 Common - hypothetical protein Pnap_0286 3 COG4801 COG4801, Predicted acyltransferase General function prediction only 121606140 Common - hypothetical protein Pnap_3250 5 None None None 121605849 Common tig trigger factor Pnap_2958 216 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 121606682 Common - sigma 54 modulation protein/ribosomal protein S30EA Pnap_3794 121 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 121605299 Common - hypothetical protein Pnap_2400 113 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 121606829 Common - Molybdenum cofactor biosynthesis enzyme-like protein Pnap_3941 114 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 121603151 Common - protein of unknown function DUF1458 Pnap_0234 39 COG3360 COG3360, Uncharacterized conserved protein Function unknown 121603019 Common - phosphoenolpyruvate carboxykinase Pnap_0102 59 COG1274 PckA, Phosphoenolpyruvate carboxykinase (GTP) Energy production and conversion 121606391 Common - multi-sensor signal transduction histidine kinase Pnap_3502 221 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 121606015 Common - polysaccharide biosynthesis protein Pnap_3125 30 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 121605475 Common - Alcohol dehydrogenase, zinc-binding domain protein Pnap_2580 179 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 121603979 Common - response regulator receiver sensor signal transduction histidine kinase Pnap_1070 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121605301 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Pnap_2402 245 COG3634 AhpF, Alkyl hydroperoxide reductase, large subunit Posttranslational modification, protein turnover, chaperones 121606612 Common - ISXo7 transposase Pnap_3724 37 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 121604680 Common - Methenyltetrahydrofolate cyclohydrolase Pnap_1778 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 121605354 Common - ABC transporter related Pnap_2456 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 121606449 Common - hypothetical protein Pnap_3561 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 121606549 Common apaG ApaG Pnap_3661 89 COG2967 ApaG, Uncharacterized protein affecting Mg2+/Co2+ transport Inorganic ion transport and metabolism 121602940 Common thiG thiazole synthase Pnap_0022 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 121605978 Common - HemY domain protein Pnap_3087 18 COG3071 HemY, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 121605964 Common - malonyl CoA-acyl carrier protein transacylase Pnap_3073 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 121603086 Common - hypothetical protein Pnap_0169 10 None None None 121606423 Common - ABC transporter related Pnap_3534 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 121604084 Common - hypothetical protein Pnap_1176 3 None None None 121602970 Nonpathogen - hypothetical protein Pnap_0052 4 None None None 121603198 Nonpathogen - hypothetical protein Pnap_0283 1 None None None 121603185 Common - putative lipoprotein transmembrane Pnap_0268 11 None None None 121603245 Common - ribosomal protein L14 Pnap_0330 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 121606780 Nonpathogen - hypothetical protein Pnap_3892 1 None None None 121604332 Common - NADH (or F420H2) dehydrogenase, subunit C Pnap_1426 157 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 121606677 Common - Dihydrodipicolinate reductase Pnap_3789 216 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 121605173 Nonpathogen - hypothetical protein Pnap_2273 1 None None None 121604282 Common - putative transmembrane protein Pnap_1375 27 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 121605168 Nonpathogen - hypothetical protein Pnap_2268 1 None None None 121604728 Common - Aldose 1-epimerase Pnap_1826 54 COG0676 COG0676, Uncharacterized enzymes related to aldose 1-epimerase Carbohydrate transport and metabolism 121604218 Common - hypothetical protein Pnap_1311 3 None None None 121603445 Common - cyclic nucleotide-binding protein Pnap_0532 106 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 121605928 Common gltA type II citrate synthase Pnap_3037 193 COG0372 GltA, Citrate synthase Energy production and conversion 121603793 Common - putative transmembrane cytochrome oxidase Pnap_0884 68 COG3346 COG3346, Uncharacterized conserved protein Function unknown 121603878 Nonpathogen - hypothetical protein Pnap_0969 1 None None None 121604193 Common - ferredoxin Pnap_1286 14 COG0633 Fdx, Ferredoxin Energy production and conversion 121606981 Common - sulphate transporter Pnap_4099 161 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 121605171 Nonpathogen - hypothetical protein Pnap_2271 1 None None None 121604071 Common - 5-oxoprolinase (ATP-hydrolyzing) Pnap_1163 117 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 121606658 Common - putative transcriptional regulator, AsnC family Pnap_3770 140 COG1522 Lrp, Transcriptional regulators Transcription 121605919 Common - hypothetical protein Pnap_3028 9 None None None 121605542 Common - hypothetical protein Pnap_2648 5 None None None 121604380 Common - UvrD/REP helicase Pnap_1474 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 121605687 Common - chorismate mutase Pnap_2793 214 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 121603587 Common - type IV pilus secretin PilQ Pnap_0676 140 COG4796 HofQ, Type II secretory pathway, component HofQ Intracellular trafficking and secretion 121606370 Common - sugar transferase Pnap_3481 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 121603110 Common - conserved hypothetical protein 701 Pnap_0193 83 COG1981 COG1981, Predicted membrane protein Function unknown 121605081 Nonpathogen - hypothetical protein Pnap_2181 3 None None None 121603829 Nonpathogen - protein of unknown function DUF1328 Pnap_0920 1 None None None 121603476 Common - sigma54 specific transcriptional regulator, Fis family Pnap_0564 169 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 121605608 Common - inner-membrane translocator Pnap_2714 157 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 121604391 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Pnap_1485 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 121606071 Common - glycosyl transferase, family 2 Pnap_3181 100 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 121603001 Common - protein of unknown function DUF891 Pnap_0084 38 COG3657 COG3657, Uncharacterized protein conserved in bacteria Function unknown 121606620 Common - restriction endonuclease Pnap_3732 24 COG1715 Mrr, Restriction endonuclease Defense mechanisms 121603165 Common - putative ATP synthase protein I Pnap_0248 16 COG3312 AtpI, F0F1-type ATP synthase, subunit I Energy production and conversion 121603467 Common - ABC transporter related Pnap_0555 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 121605530 Common - succinic semialdehyde dehydrogenase Pnap_2636 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 121605618 Common - ferredoxin Pnap_2724 112 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 121606930 Common - response regulator receiver sensor signal transduction histidine kinase Pnap_4047 219 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 121605634 Common - two component transcriptional regulator, winged helix family Pnap_2740 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 121605405 Common - Conjugal transfer protein Pnap_2509 33 COG3701 TrbF, Type IV secretory pathway, TrbF components Intracellular trafficking and secretion 121606692 Nonpathogen - hypothetical protein Pnap_3804 1 None None None 121606480 Nonpathogen - hypothetical protein Pnap_3592 3 None None None 121606529 Common - ribosomal protein L7/L12 Pnap_3641 212 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 121604085 Common - protein of unknown function DUF455 Pnap_1177 47 COG2833 COG2833, Uncharacterized protein conserved in bacteria Function unknown 121605997 Common - integral membrane sensor signal transduction histidine kinase Pnap_3106 211 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121605807 Common - riboflavin synthase subunit alpha Pnap_2916 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 121603592 Common - Extracellular ligand-binding receptor Pnap_0681 99 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 121605273 Common - Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B Pnap_2374 86 COG3384 COG3384, Uncharacterized conserved protein Function unknown 121606976 Nonpathogen - hypothetical protein Pnap_4093 1 None None None 121604563 Common - 3-carboxy-cis,cis-muconate cycloisomerase Pnap_1657 158 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 121605071 Common - permease YjgP/YjgQ family protein Pnap_2171 125 COG0795 COG0795, Predicted permeases General function prediction only 121605989 Common - argininosuccinate lyase Pnap_3098 234 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 121603688 Nonpathogen - hypothetical protein Pnap_0777 1 None None None 121605151 Nonpathogen - hypothetical protein Pnap_2251 2 None None None 121604051 Common - ABC-3 protein Pnap_1143 168 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 121604203 Common - Alpha/beta hydrolase fold-3 domain protein Pnap_1296 79 COG0657 Aes, Esterase/lipase Lipid metabolism 121603709 Common - short-chain dehydrogenase/reductase SDR Pnap_0798 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 121606699 Common - fumarate lyase Pnap_3811 233 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 121603238 Nonpathogen - hypothetical protein Pnap_0323 1 None None None 121606293 Common - transposase, IS605 OrfB Pnap_3404 64 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 121603180 Common - cytochrome c, class I Pnap_0263 45 COG3245 CycB, Cytochrome c5 Energy production and conversion 121606385 Common - transcriptional regulator, TetR family Pnap_3496 41 COG1309 AcrR, Transcriptional regulator Transcription 121604509 Nonpathogen - hypothetical protein Pnap_1603 2 None None None 121603068 Common - two component transcriptional regulator, winged helix family Pnap_0151 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 121604777 Common - Pyrrolo-quinoline quinone Pnap_1875 94 COG1520 COG1520, FOG: WD40-like repeat Function unknown 121605117 Common - transcriptional regulator, AraC family Pnap_2217 65 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 121604528 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Pnap_1622 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 121605969 Common rpmF 50S ribosomal protein L32 Pnap_3078 98 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 121605116 Common - major facilitator superfamily MFS_1 Pnap_2216 101 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 121605825 Common - Glutamate--tRNA ligase Pnap_2934 240 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 121603483 Common - Redoxin domain protein Pnap_0571 146 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 121604928 Common - Protocatechuate 4,5-dioxygenase Pnap_2027 31 COG3384 COG3384, Uncharacterized conserved protein Function unknown 121605549 Nonpathogen - hypothetical protein Pnap_2655 3 None None None 121603660 Common obgE GTPase ObgE Pnap_0749 247 COG0536 Obg, Predicted GTPase General function prediction only 121604413 Nonpathogen - hypothetical protein Pnap_1507 1 None None None 121604854 Common - PAS/PAC sensor signal transduction histidine kinase Pnap_1953 216 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 121606997 Common - hypothetical protein Pnap_4115 6 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 121602999 Common - protein of unknown function DUF214 Pnap_0081 135 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 121603330 Common - Recombinase Pnap_0415 47 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 121605444 Common - 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Pnap_2549 187 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 121605535 Common - integral membrane sensor signal transduction histidine kinase Pnap_2641 133 COG3851 UhpB, Signal transduction histidine kinase, glucose-6-phosphate specific Signal transduction mechanisms 121606093 Common - NAD-dependent epimerase/dehydratase Pnap_3203 62 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 121603337 Common - IS66 Orf2 family protein Pnap_0423 34 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 121604361 Common - short-chain dehydrogenase/reductase SDR Pnap_1455 229 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 121605940 Common - peptidase S16, lon domain protein Pnap_3049 55 COG2802 COG2802, Uncharacterized protein, similar to the N-terminal domain of Lon protease General function prediction only 121606398 Common - acyl-coA-binding protein, ACBP Pnap_3509 20 COG4281 ACB, Acyl-CoA-binding protein Lipid metabolism 121606408 Common - ABC transporter related Pnap_3519 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 121606992 Common - hypothetical protein Pnap_4110 4 None None None 121606485 Common - two component transcriptional regulator, LuxR family Pnap_3597 188 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 121606343 Common - TRAP dicarboxylate transporter, DctP subunit Pnap_3454 107 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 121605129 Common - molybdopterin-guanine dinucleotide biosynthesis protein B Pnap_2229 114 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 121605468 Common - protein of unknown function UPF0005 Pnap_2573 125 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 121604828 Common - exodeoxyribonuclease VII, large subunit Pnap_1926 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 121604953 Common - glycosyl transferase, family 2 Pnap_2052 129 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 121603731 Common - PHP C-terminal domain protein Pnap_0820 65 COG1796 POL4, DNA polymerase IV (family X) DNA replication, recombination, and repair 121606906 Common - amidase, hydantoinase/carbamoylase family Pnap_4022 86 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 121603702 Common - response regulator receiver protein Pnap_0791 179 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 121605307 Common - pentapeptide repeat protein Pnap_2408 2 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 121604558 Common - inner-membrane translocator Pnap_1652 152 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 121605027 Common - cyclohexanecarboxylate-CoA ligase Pnap_2126 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 121606607 Common - nicotinate phosphoribosyltransferase Pnap_3719 107 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 121606086 Common - polysaccharide export protein Pnap_3196 121 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 121605846 Common - ATP-dependent protease La Pnap_2955 218 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 121604833 Common - hypothetical protein Pnap_1931 56 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 121606680 Common - HPr kinase/phosphorylase Pnap_3792 57 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 121606444 Common - transposase, IS4 family protein Pnap_3556 47 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 121605349 Common - hypothetical protein Pnap_2450 6 None None None 121603047 Common - hypothetical protein Pnap_0130 33 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 121605753 Common - spermidine/putrescine ABC transporter ATPase subunit Pnap_2861 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 121604622 Common - acetolactate synthase 3 catalytic subunit Pnap_1717 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 121606661 Common - hypothetical protein Pnap_3773 7 COG2836 COG2836, Uncharacterized conserved protein Function unknown 121606839 Common - succinyl-CoA synthetase subunit alpha Pnap_3952 210 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 121606901 Common - protein of unknown function DUF891 Pnap_4017 42 COG3657 COG3657, Uncharacterized protein conserved in bacteria Function unknown 121605646 Common - hypothetical protein Pnap_2752 10 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 121602941 Common - thiamine-phosphate pyrophosphorylase Pnap_0023 204 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 121606318 Common - cobalamin synthesis protein, P47K Pnap_3429 126 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 121605954 Common - signal peptidase I Pnap_3063 211 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 121603162 Common - protein of unknown function DUF493 Pnap_0245 39 COG2921 COG2921, Uncharacterized conserved protein Function unknown 121605389 Nonpathogen - hypothetical protein Pnap_2493 1 None None None 121603554 Common - hypothetical protein Pnap_0643 5 None None None 121606967 Common - two component transcriptional regulator, LuxR family Pnap_4084 162 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 121606227 Common - peptidylprolyl isomerase, FKBP-type Pnap_3338 108 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 121602990 Nonpathogen - hypothetical protein Pnap_0072 1 None None None 121606499 Common - hypothetical protein Pnap_3611 41 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 121606021 Common - glycosyl transferase, family 4 Pnap_3131 98 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 121603172 Common - F0F1 ATP synthase subunit beta Pnap_0255 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 121603539 Common - phage integrase family protein Pnap_0628 9 None None None 121605777 Common - transporter, hydrophobe/amphiphile efflux-1 (HAE1) family Pnap_2886 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 121606181 Common - phage major capsid protein, P2 family Pnap_3291 22 None None None 121603570 Nonpathogen - hypothetical protein Pnap_0659 1 None None None 121603216 Common - hypothetical protein Pnap_0301 15 None None None 121603322 Common - conserved repeat domain Pnap_0407 12 None None None 121604246 Common - transcriptional regulator, LysR family Pnap_1339 148 COG0583 LysR, Transcriptional regulator Transcription 121605373 Common - Glutathione S-transferase, C-terminal domain Pnap_2477 96 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 121605148 Common - phage tail tape measure protein, TP901 family Pnap_2248 41 COG3941 COG3941, Mu-like prophage protein General function prediction only 121603950 Common - protein of unknown function DUF1228 Pnap_1041 61 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 121604932 Common - hypothetical protein Pnap_2031 79 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 121605648 Common - Cupin 2, conserved barrel domain protein Pnap_2754 7 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 121605280 Common - carboxyl transferase Pnap_2381 205 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 121606280 Common - acetyl-CoA carboxylase, biotin carboxylase Pnap_3391 232 COG0439 AccC, Biotin carboxylase Lipid metabolism 121603027 Common - MOSC domain containing protein Pnap_0110 76 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 121605357 Common - inner-membrane translocator Pnap_2459 139 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 121606832 Common - Fimbrial protein pilin Pnap_3944 71 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 121605461 Nonpathogen - hypothetical protein Pnap_2566 2 None None None 121604933 Common - amidohydrolase 2 Pnap_2032 28 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 121605391 Nonpathogen - hypothetical protein Pnap_2495 1 None None None 121604065 Common - DNA mismatch repair protein MutL Pnap_1157 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 121605486 Common - efflux transporter, RND family, MFP subunit Pnap_2591 163 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 121604013 Common - 1,4-alpha-glucan branching enzyme Pnap_1104 144 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 121606739 Common - hypothetical protein Pnap_3851 30 None None None 121604808 Common - inner-membrane translocator Pnap_1906 123 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 121604793 Nonpathogen - hypothetical protein Pnap_1891 1 None None None 121603397 Common - protein of unknown function DUF485 Pnap_0484 39 COG3162 COG3162, Predicted membrane protein Function unknown 121606313 Common - cell division protein FtsL Pnap_3424 12 COG3116 FtsL, Cell division protein Cell division and chromosome partitioning 121603040 Common glcE glycolate oxidase FAD binding subunit Pnap_0123 151 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 121606841 Common - N-acetyl-gamma-glutamyl-phosphate reductase Pnap_3954 203 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 121605188 Common - iron-sulfur cluster assembly protein IscA Pnap_2288 163 COG0316 IscA, Uncharacterized conserved protein Function unknown 121605051 Common - uroporphyrin-III C-methyltransferase Pnap_2151 198 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 121606689 Common - methylmalonate-semialdehyde dehydrogenase Pnap_3801 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 121604239 Common - thioredoxin Pnap_1332 231 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 121603580 Common - diaminopimelate decarboxylase Pnap_0669 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 121605487 Common - acriflavin resistance protein Pnap_2592 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 121606593 Common - filamentous haemagglutinin family outer membrane protein Pnap_3705 98 None None None 121606887 Common - major facilitator superfamily MFS_1 Pnap_4003 179 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 121603452 Common - helix-turn-helix domain protein Pnap_0540 49 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 121605226 Nonpathogen - heat shock protein DnaJ domain protein Pnap_2326 5 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 121606505 Common - salicylyl-CoA 5-hydroxylase Pnap_3617 177 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 121604479 Nonpathogen - hypothetical protein Pnap_1573 1 None None None 121605748 Common - isocitrate lyase Pnap_2855 128 COG2224 AceA, Isocitrate lyase Energy production and conversion 121606106 Common - fatty acid desaturase Pnap_3216 65 COG1398 OLE1, Fatty-acid desaturase Lipid metabolism 121605214 Common - electron transfer flavoprotein beta-subunit Pnap_2314 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 121604860 Common - hydrogenase expression/formation protein HypE Pnap_1959 169 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 121604325 Common - ribosomal protein S15 Pnap_1419 214 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 121606709 Common - major facilitator superfamily MFS_1 Pnap_3821 147 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 121602955 Common - hypothetical protein Pnap_0037 53 COG3665 COG3665, Uncharacterized conserved protein Function unknown 121606172 Common - AMP-dependent synthetase and ligase Pnap_3282 220 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 121606896 Common - protein of unknown function DUF1232 Pnap_4012 41 COG3339 COG3339, Uncharacterized conserved protein Function unknown 121603983 Common - alpha/beta hydrolase fold Pnap_1074 71 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 121604344 Common - putative transmembrane protein Pnap_1438 16 None None None 121604887 Common - glyceraldehyde-3-phosphate dehydrogenase, type I Pnap_1986 218 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 121605852 Common - Squalene/phytoene synthase Pnap_2961 90 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 121603614 Common - phosphoribosyl-ATP pyrophosphohydrolase Pnap_0703 153 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 121605595 Common - acyl-CoA dehydrogenase domain protein Pnap_2701 159 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 121606061 Common - NUDIX hydrolase Pnap_3171 115 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 121606490 Common - potassium-transporting ATPase, C subunit Pnap_3602 95 COG2156 KdpC, K+-transporting ATPase, c chain Inorganic ion transport and metabolism 121605904 Common - Aldehyde dehydrogenase (NAD(+)) Pnap_3013 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 121606515 Common - putative transcriptional regulator, Crp/Fnr family Pnap_3627 28 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 121606720 Common - ABC transporter related Pnap_3832 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 121605401 Common - Type IV secretory pathway TrbL components-like protein Pnap_2505 40 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 121606946 Common - polar amino acid ABC transporter, inner membrane subunit Pnap_4063 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 121605653 Common - alpha/beta hydrolase fold Pnap_2759 68 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 121603605 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Pnap_0694 219 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 121603728 Nonpathogen - hypothetical protein Pnap_0817 1 None None None 121605833 Common - oxidoreductase FAD/NAD(P)-binding domain protein Pnap_2942 117 COG0369 CysJ, Sulfite reductase, alpha subunit (flavoprotein) Inorganic ion transport and metabolism 121606668 Common - Cbb3-type cytochrome oxidase component Pnap_3780 14 COG4736 CcoQ, Cbb3-type cytochrome oxidase, subunit 3 Posttranslational modification, protein turnover, chaperones 121606186 Common - prophage LambdaSo, lysozyme, putative Pnap_3296 11 COG3772 COG3772, Phage-related lysozyme (muraminidase) General function prediction only 121603620 Common - peptidase S1 and S6, chymotrypsin/Hap Pnap_0709 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 121605095 Common - thioredoxin Pnap_2195 234 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 121603459 Common - luciferase family protein Pnap_0547 97 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 121606031 Nonpathogen - hypothetical protein Pnap_3141 1 COG3793 TerB, Tellurite resistance protein Inorganic ion transport and metabolism 121605161 Nonpathogen - hypothetical protein Pnap_2261 1 None None None 121604480 Common - nitrogenase cofactor biosynthesis protein NifB Pnap_1574 67 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 121604568 Common - metallophosphoesterase Pnap_1662 85 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 121603960 Nonpathogen - hypothetical protein Pnap_1051 5 None None None 121606416 Common - ABC transporter related Pnap_3527 247 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 121606814 Common - DNA-directed DNA polymerase Pnap_3926 151 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 121606848 Common - regulatory protein, putative Pnap_3961 73 COG3901 NosR, Regulator of nitric oxide reductase transcription Transcription 121605158 Common - hypothetical protein Pnap_2258 3 COG4220 COG4220, Phage DNA packaging protein, Nu1 subunit of terminase DNA replication, recombination, and repair 121603052 Common - 2-dehydropantoate 2-reductase Pnap_0135 100 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 121604316 Common - protein kinase Pnap_1410 130 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 121605140 Nonpathogen - hypothetical protein Pnap_2240 1 None None None 121605796 Nonpathogen - hypothetical protein Pnap_2905 1 None None None 121604538 Common - tartrate dehydrogenase Pnap_1632 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 121604623 Common ilvH acetolactate synthase 3 regulatory subunit Pnap_1718 192 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 121605414 Nonpathogen - hypothetical protein Pnap_2518 6 None None None 121604007 Common - protein of unknown function DUF1345 Pnap_1098 41 COG4291 COG4291, Predicted membrane protein Function unknown 121604287 Common - tRNA/rRNA methyltransferase (SpoU) Pnap_1381 153 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 121604841 Common - Rhodanese domain protein Pnap_1939 108 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 121604636 Common - iojap-like protein Pnap_1732 194 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 121606454 Common - Poly-beta-hydroxybutyrate polymerase domain protein Pnap_3566 76 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 121603295 Nonpathogen - cytochrome B561 Pnap_0380 3 COG3038 CybB, Cytochrome B561 Energy production and conversion 121604441 Common - two component transcriptional regulator, winged helix family Pnap_1535 218 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 121604234 Common - transcriptional regulator, BadM/Rrf2 family Pnap_1327 95 COG1959 COG1959, Predicted transcriptional regulator Transcription 121603388 Common - putative transmembrane protein Pnap_0474 20 None None None 121603847 Common - quinolinate synthetase Pnap_0938 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 121604352 Common - drug resistance transporter, EmrB/QacA subfamily Pnap_1446 208 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 121605065 Common - 6-phosphogluconate dehydrogenase, NAD-binding Pnap_2165 24 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 121603329 Nonpathogen - hypothetical protein Pnap_0414 2 None None None 121606578 Common - maltoporin precursor Pnap_3690 25 COG4580 LamB, Maltoporin (phage lambda and maltose receptor) Carbohydrate transport and metabolism 121606216 Common - hypothetical protein Pnap_3327 6 None None None 121604320 Common - twin-arginine translocation pathway signal Pnap_1414 91 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 121606461 Common - ABC transporter related Pnap_3573 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 121603744 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Pnap_0835 176 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 121606794 Common - transcriptional regulator, LysR family Pnap_3906 168 COG0583 LysR, Transcriptional regulator Transcription 121604464 Common - TRAP dicarboxylate transporter, DctP subunit Pnap_1558 113 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 121603834 Common - UBA/THIF-type NAD/FAD binding protein Pnap_0925 223 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 121606287 Common - phospho-2-dehydro-3-heoxyheptonate aldolase Pnap_3398 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 121605253 Nonpathogen - hypothetical protein Pnap_2354 4 None None None 121605906 Nonpathogen - hypothetical protein Pnap_3015 5 None None None 121603091 Common - rod shape-determining protein MreC Pnap_0174 142 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 121603170 Common - ATP synthase F1, alpha subunit Pnap_0253 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 121603781 Common - glutathione-regulated potassium-efflux system protein KefC Pnap_0872 162 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 121603354 Common - apolipoprotein N-acyltransferase Pnap_0440 157 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 121605722 Common - acriflavin resistance protein Pnap_2828 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 121606339 Common - hypothetical protein Pnap_3450 34 COG1432 COG1432, Uncharacterized conserved protein Function unknown 121604181 Common - protein of unknown function DUF344 Pnap_1274 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 121605436 Common - OmpA domain protein transmembrane region-containing protein Pnap_2541 20 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 121604217 Common - hypothetical protein Pnap_1310 20 COG3431 COG3431, Predicted membrane protein Function unknown 121604659 Common - amidase Pnap_1757 215 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 121606713 Common - two component transcriptional regulator, winged helix family Pnap_3825 211 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 121603000 Nonpathogen - hypothetical protein Pnap_0082 1 None None None 121604673 Common - lipid-A-disaccharide synthase Pnap_1771 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 121605990 Common - hypothetical protein Pnap_3099 19 COG3514 COG3514, Uncharacterized protein conserved in bacteria Function unknown 121605883 Common - HAD-superfamily subfamily IB hydrolase, TIGR01490 Pnap_2992 68 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 121605893 Common - transcriptional regulator, AraC family Pnap_3002 80 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 121604014 Common - glycogen/starch/alpha-glucan phosphorylases Pnap_1105 144 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 121603070 Common - peptidase M48, Ste24p Pnap_0153 123 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 121605681 Common - phosphoglycolate phosphatase Pnap_2787 196 COG0546 Gph, Predicted phosphatases General function prediction only 121604091 Common eno phosphopyruvate hydratase Pnap_1183 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 121605202 Common - ABC transporter related Pnap_2302 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 121603904 Common - hypothetical protein Pnap_0995 14 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 121605230 Common - H+-transporting two-sector ATPase, C subunit Pnap_2331 46 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 121604047 Nonpathogen - hypothetical protein Pnap_1139 2 None None None 121603392 Common - YbaK/prolyl-tRNA synthetase associated region Pnap_0478 86 COG2606 EbsC, Uncharacterized conserved protein Function unknown 121606245 Common - Phosphomethylpyrimidine kinase type-1 Pnap_3356 188 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 121604714 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase Pnap_1812 139 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 121606073 Common - glycosyl transferase, group 1 Pnap_3183 143 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 121604983 Common - putative signal-transduction protein with CBS domains Pnap_2082 76 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 121603768 Common - hypothetical protein Pnap_0859 88 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 121605785 Common - TPR repeat-containing protein Pnap_2894 61 COG4785 NlpI, Lipoprotein NlpI, contains TPR repeats General function prediction only 121603818 Common hrcA heat-inducible transcription repressor Pnap_0909 150 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 121602925 Common - cell division topological specificity factor MinE Pnap_0007 86 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 121605056 Common - cobalamin (vitamin B12) biosynthesis CbiG protein Pnap_2156 16 COG2073 CbiG, Cobalamin biosynthesis protein CbiG Coenzyme metabolism 121605693 Common - hypothetical protein Pnap_2799 59 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 121605067 Nonpathogen - hypothetical protein Pnap_2167 1 None None None 121605237 Common - AAA ATPase, central domain protein Pnap_2338 99 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 121603957 Nonpathogen - hypothetical protein Pnap_1048 1 None None None 121604153 Common - protein of unknown function DUF1415 Pnap_1246 30 COG3310 COG3310, Uncharacterized protein conserved in bacteria Function unknown 121603520 Common - major facilitator superfamily MFS_1 Pnap_0609 224 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 121606868 Common - hypothetical protein Pnap_3982 3 None None None 121606111 Common - putative transcriptional regulator, AsnC family Pnap_3221 151 COG1522 Lrp, Transcriptional regulators Transcription 121604904 Common - protein of unknown function UPF0125 Pnap_2003 57 COG2914 COG2914, Uncharacterized protein conserved in bacteria Function unknown 121606777 Nonpathogen - hypothetical protein Pnap_3889 1 None None None 121604111 Common - Endoribonuclease L-PSP Pnap_1204 92 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 121604625 Common - CDP-diacylglycerol--serine O-phosphatidyltransferase Pnap_1720 147 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 121605030 Common - Acyl-CoA dehydrogenase Pnap_2129 166 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 121605791 Common - transposase Pnap_2900 15 None None None 121606156 Common - putative transcriptional regulator, Crp/Fnr family Pnap_3266 40 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 121604172 Nonpathogen - hypothetical protein Pnap_1265 1 None None None 121605324 Common - extracellular ligand-binding receptor Pnap_2425 128 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 121603020 Nonpathogen - hypothetical protein Pnap_0103 1 None None None 121605959 Common - RNA polymerase sigma factor RpoE Pnap_3068 173 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 121605561 Common - transcriptional regulator, LysR family Pnap_2667 184 COG0583 LysR, Transcriptional regulator Transcription 121606325 Common - transcriptional regulator, LysR family Pnap_3436 64 COG0583 LysR, Transcriptional regulator Transcription 121604296 Common - hypothetical protein Pnap_1390 33 COG4680 COG4680, Uncharacterized protein conserved in bacteria Function unknown 121603603 Common - ABC-2 type transporter Pnap_0692 145 COG1511 COG1511, Predicted membrane protein Function unknown 121605615 Common - low molecular weight phosphotyrosine protein phosphatase Pnap_2721 21 COG4551 COG4551, Predicted protein tyrosine phosphatase General function prediction only 121606503 Common - hypothetical protein Pnap_3615 5 None None None 121606149 Common - TRAP-type uncharacterized transport system protein, periplasmic component Pnap_3259 9 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 121604118 Common - conserved hypothetical protein, putative DNA helicase Pnap_1211 90 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 121603050 Common - DNA polymerase, beta domain protein region Pnap_0133 17 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 121604117 Common - Alcohol dehydrogenase GroES domain protein Pnap_1210 152 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 121605240 Common - hypothetical protein Pnap_2341 6 None None None 121606405 Common - Rhodanese domain protein Pnap_3516 33 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 121606566 Common - hypothetical protein Pnap_3678 19 None None None 121606740 Common - Alcohol dehydrogenase, zinc-binding domain protein Pnap_3852 211 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 121606760 Common - PAP2 (acid phosphatase) superfamily protein-like protein Pnap_3872 19 COG3907 COG3907, PAP2 (acid phosphatase) superfamily protein General function prediction only 121604023 Nonpathogen - hypothetical protein Pnap_1115 5 COG5591 COG5591, Uncharacterized conserved protein Function unknown 121605367 Nonpathogen - recombinase Pnap_2470 15 None None None 121606183 Common - phage head completion Pnap_3293 17 None None None 121603373 Common - acyl-CoA dehydrogenase domain protein Pnap_0459 169 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 121603315 Common - phenazine biosynthesis protein PhzF family Pnap_0400 109 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 121604698 Common - Glutaredoxin-family domain protein Pnap_1796 100 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 121606052 Common - globin Pnap_3162 22 COG2346 COG2346, Truncated hemoglobins General function prediction only 121603608 Common - histidinol-phosphate aminotransferase Pnap_0697 227 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 121605428 Common - Relaxase/mobilization nuclease family protein Pnap_2533 17 None None None 121606437 Common - ABC transporter related Pnap_3549 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 121606430 Common - ATPase-like protein Pnap_3541 29 COG1106 COG1106, Predicted ATPases General function prediction only 121606122 Common - Alcohol dehydrogenase, zinc-binding domain protein Pnap_3232 195 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 121604109 Common - hypothetical protein Pnap_1202 10 None None None 121603413 Common rplM 50S ribosomal protein L13 Pnap_0500 219 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 121604869 Common - HupH hydrogenase expression protein Pnap_1968 20 None None None 121606616 Common - response regulator receiver sensor signal transduction histidine kinase Pnap_3728 162 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121604105 Common - major facilitator superfamily MFS_1 Pnap_1198 104 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 121606257 Common - peptidase M61 domain protein Pnap_3368 55 COG3975 COG3975, Predicted protease with the C-terminal PDZ domain General function prediction only 121606556 Nonpathogen - hypothetical protein Pnap_3668 1 None None None 121603893 Common - DEAD_2 domain protein Pnap_0984 86 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 121604801 Common - filamentation induced by cAMP protein Fic Pnap_1899 69 COG3177 COG3177, Uncharacterized conserved protein Function unknown 121603057 Common - hypothetical protein Pnap_0140 5 None None None 121605571 Common - thioesterase superfamily protein Pnap_2677 50 COG0824 FcbC, Predicted thioesterase General function prediction only 121605707 Common - Roadblock/LC7 family protein Pnap_2813 27 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 121603079 Common - transcriptional regulator, TetR family Pnap_0162 87 COG1309 AcrR, Transcriptional regulator Transcription 121606129 Common - type II secretion system protein E Pnap_3239 202 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 121603033 Common - cyclic nucleotide-binding protein Pnap_0116 25 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 121603342 Common - hypothetical protein Pnap_0428 25 COG5659 COG5659, FOG: Transposase DNA replication, recombination, and repair 121603566 Common - Glucose-6-phosphate isomerase Pnap_0655 187 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 121604653 Common - transposase IS116/IS110/IS902 family protein Pnap_1751 76 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 121606732 Common - phage SPO1 DNA polymerase-related protein Pnap_3844 29 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 121606264 Common - hypothetical protein Pnap_3375 3 None None None 121605588 Common - molybdopterin dehydrogenase, FAD-binding Pnap_2694 38 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 121606135 Common - ATPase associated with various cellular activities, AAA_3 Pnap_3245 176 COG0714 COG0714, MoxR-like ATPases General function prediction only 121603753 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Pnap_0844 154 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 121606142 Common - hypothetical protein Pnap_3252 5 COG5137 COG5137, Histone chaperone involved in gene silencing Transcription / Chromatin structure and dynamics 121603428 Common - hypothetical protein Pnap_0515 5 None None None 121603348 Common - glucose-methanol-choline oxidoreductase Pnap_0434 54 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 121605013 Common - Rieske (2Fe-2S) domain protein Pnap_2112 82 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 121603946 Common - inner-membrane translocator Pnap_1037 105 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 121604230 Common - heat shock protein Hsp20 Pnap_1323 129 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 121605247 Common - Ankyrin Pnap_2348 80 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 121606355 Common - NAD-dependent epimerase/dehydratase Pnap_3466 125 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 121604274 Common - glycosyl transferase, family 2 Pnap_1367 116 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 121605593 Common - NUDIX hydrolase Pnap_2699 48 None None None 121604930 Common - amidohydrolase 2 Pnap_2029 43 COG3618 COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 121603685 Common - modification methylase, HemK family Pnap_0774 215 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 121604521 Common - nitroreductase Pnap_1615 60 COG0778 NfnB, Nitroreductase Energy production and conversion 121606046 Common - cytochrome c, class I Pnap_3156 51 None None None 121606213 Nonpathogen - hypothetical protein Pnap_3324 1 COG2378 COG2378, Predicted transcriptional regulator Transcription 121606366 Common - acyl-CoA dehydrogenase domain protein Pnap_3477 150 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 121605564 Common - integral membrane sensor signal transduction histidine kinase Pnap_2670 102 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121603885 Common - HupE/UreJ protein Pnap_0976 15 COG2370 HupE, Hydrogenase/urease accessory protein Posttranslational modification, protein turnover, chaperones 121603140 Common - L-carnitine dehydratase/bile acid-inducible protein F Pnap_0223 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 121605876 Common - 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase Pnap_2985 125 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 121604615 Common - nitrogen regulatory protein P-II Pnap_1710 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 121604495 Common - protein of unknown function UPF0061 Pnap_1589 110 COG0397 COG0397, Uncharacterized conserved protein Function unknown 121606291 Common - putative transposase, IS891/IS1136/IS1341 family Pnap_3402 42 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 121604379 Common - hypothetical protein Pnap_1473 4 None None None 121603477 Common - thiol:disulfide interchange protein, putative Pnap_0565 74 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 121606767 Common - Peptidoglycan-binding LysM Pnap_3879 46 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 121604806 Common - ABC transporter related Pnap_1904 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 121606592 Common - Polypeptide-transport-associated domain protein, ShlB-type Pnap_3704 64 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 121606472 Common - peptidase M23B Pnap_3584 166 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 121604209 Common - dihydrouridine synthase, DuS Pnap_1302 207 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 121604541 Common - 2'-5' RNA ligase Pnap_1635 11 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 121603501 Common - heme exporter protein CcmA Pnap_0589 247 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 121603837 Common - Rhodanese domain protein Pnap_0928 171 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 121604786 Common - phosphoribosyltransferase Pnap_1884 57 COG2236 COG2236, Predicted phosphoribosyltransferases General function prediction only 121606768 Common - transposase, IS605 OrfB family Pnap_3880 75 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 121604438 Common - mono-heme class I cytochrome c Pnap_1532 13 None None None 121605334 Common - phosphomethylpyrimidine kinase Pnap_2435 218 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 121604548 Common - hypothetical protein Pnap_1642 23 COG4267 COG4267, Predicted membrane protein Function unknown 121605669 Common - putative transmembrane protein Pnap_2775 13 None None None 121603912 Common - hypothetical protein Pnap_1003 7 None None None 121605360 Common - aromatic-ring-hydroxylating dioxygenase, beta subunit Pnap_2462 12 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 121604719 Common - protein of unknown function DUF454 Pnap_1817 15 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 121604551 Common - hypothetical protein Pnap_1645 11 None None None 121605198 Common - UspA domain protein Pnap_2298 41 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 121603011 Common - D-amino-acid dehydrogenase Pnap_0094 116 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 121605734 Nonpathogen - hypothetical protein Pnap_2840 1 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 121606204 Common - phage P2 GpU family protein Pnap_3314 29 COG3499 COG3499, Phage protein U General function prediction only 121605263 Common - periplasmic binding protein Pnap_2364 161 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 121604431 Common - chaperone protein DnaJ Pnap_1525 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 121606609 Common - NUDIX hydrolase Pnap_3721 95 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 121605009 Common - major facilitator superfamily MFS_1 Pnap_2108 179 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 121605730 Common - protein of unknown function DUF214 Pnap_2836 43 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 121606828 Nonpathogen - hypothetical protein Pnap_3940 1 None None None 121602981 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA Pnap_0063 192 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 121605700 Common - protein of unknown function DUF152 Pnap_2806 159 COG1496 COG1496, Uncharacterized conserved protein Function unknown 121603335 Common - hypothetical protein Pnap_0421 23 None None None 121605554 Common - ribosomal subunit interface protein, putative Pnap_2660 18 None None None 121603369 Common - acyl-CoA dehydrogenase domain protein Pnap_0455 169 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 121603999 Common - Sporulation domain protein Pnap_1090 15 COG3147 DedD, Uncharacterized protein conserved in bacteria Function unknown 121603254 Common - ribosomal protein L15 Pnap_0339 216 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 121603747 Nonpathogen - hypothetical protein Pnap_0838 3 None None None 121604268 Common - transcriptional regulator, LysR family Pnap_1361 127 COG0583 LysR, Transcriptional regulator Transcription 121605311 Common - DSBA oxidoreductase Pnap_2412 85 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 121605936 Common - Phosphoribosylanthranilate isomerase Pnap_3045 190 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 121603304 Common - chaperonin GroEL Pnap_0389 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 121602933 Nonpathogen - hypothetical protein Pnap_0015 2 None None None 121604669 Common - outer membrane chaperone Skp (OmpH) Pnap_1767 89 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 121606220 Common - phage Gp37Gp68 family protein Pnap_3331 43 COG4422 COG4422, Bacteriophage protein gp37 Function unknown 121604366 Common - GCN5-related N-acetyltransferase Pnap_1460 87 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 121605441 Common ompR osmolarity response regulator Pnap_2546 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 121603700 Common - histidine kinase Pnap_0789 128 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 121604502 Common - 5-dehydro-4-deoxyglucarate dehydratase Pnap_1596 210 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 121606302 Common - cell division protein FtsA Pnap_3413 196 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 121606603 Common - PilT protein domain protein Pnap_3715 37 COG3744 COG3744, Uncharacterized protein conserved in bacteria Function unknown 121605678 Common - polysaccharide deacetylase Pnap_2784 36 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 121604745 Common - acetyl-CoA acetyltransferase Pnap_1843 169 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 121604294 Common rpsU 30S ribosomal protein S21 Pnap_1388 69 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 121604835 Common - ATP-dependent Clp protease adaptor protein ClpS Pnap_1933 118 COG2127 COG2127, Uncharacterized conserved protein Function unknown 121606017 Nonpathogen - hypothetical protein Pnap_3127 1 None None None 121606250 Common - hypothetical protein Pnap_3361 77 COG1238 COG1238, Predicted membrane protein Function unknown 121603096 Nonpathogen - hypothetical protein Pnap_0179 3 None None None 121603921 Nonpathogen - hypothetical protein Pnap_1012 7 None None None 121606397 Common - Uncharacterized protein UPF0065 Pnap_3508 74 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121605478 Common - transcriptional regulator, LysR family Pnap_2583 115 COG0583 LysR, Transcriptional regulator Transcription 121603431 Common - short-chain dehydrogenase/reductase SDR Pnap_0518 216 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 121603854 Common - DTW domain containing protein Pnap_0945 27 COG3148 COG3148, Uncharacterized conserved protein Function unknown 121604300 Common - transposase, IS4 family protein Pnap_1394 31 None None None 121606705 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase Pnap_3817 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 121603359 Common - hypothetical protein Pnap_0445 2 None None None 121604946 Common - Rieske (2Fe-2S) domain protein Pnap_2045 15 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 121605800 Common - pilus assembly protein Pnap_2909 12 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 121604131 Common - electron transfer flavoprotein, alpha subunit Pnap_1224 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 121604606 Common hppA membrane-bound proton-translocating pyrophosphatase Pnap_1701 98 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 121604735 Common - transposase, IS605 OrfB family Pnap_1833 61 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 121605506 Common - ribosomal RNA methyltransferase RrmJ/FtsJ Pnap_2612 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 121605714 Common - sigma54 specific transcriptional regulator, Fis family Pnap_2820 171 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 121604517 Common - Patatin Pnap_1611 120 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 121605098 Common - hypothetical protein Pnap_2198 17 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 121603715 Common - porin, gram-negative type Pnap_0804 27 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 121603936 Common - transcriptional regulator, XRE family Pnap_1027 96 COG1396 HipB, Predicted transcriptional regulators Transcription 121606348 Common - transcriptional regulator, LysR family Pnap_3459 166 COG0583 LysR, Transcriptional regulator Transcription 121603972 Common - transglutaminase domain protein Pnap_1063 111 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 121606913 Common - cytochrome P450 Pnap_4029 77 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 121604481 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Pnap_1575 101 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 121604823 Common - 3-deoxy-D-manno-octulosonate cytidylyltransferase Pnap_1921 137 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 121605933 Common - aspartate-semialdehyde dehydrogenase Pnap_3042 193 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 121605827 Common - tRNA (guanine-N(7)-)-methyltransferase Pnap_2936 178 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 121605863 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Pnap_2972 60 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 121603696 Common - putative regulatory protein, FmdB family Pnap_0785 73 COG2331 COG2331, Uncharacterized protein conserved in bacteria Function unknown 121604194 Common - GCN5-related N-acetyltransferase Pnap_1287 59 COG0456 RimI, Acetyltransferases General function prediction only 121606197 Common - hypothetical protein Pnap_3307 4 None None None 121603527 Common - monooxygenase, FAD-binding Pnap_0616 121 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 121604164 Nonpathogen - hypothetical protein Pnap_1257 1 None None None 121603707 Common - feruloyl-CoA synthase Pnap_0796 187 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 121603283 Nonpathogen - hypothetical protein Pnap_0368 2 None None None 121604123 Common - lytic murein transglycosylase B Pnap_1216 103 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 121604736 Common - Intracellular septation protein A Pnap_1834 89 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 121606889 Nonpathogen - hypothetical protein Pnap_4005 8 None None None 121604476 Common - transcriptional regulator, NifA, Fis Family Pnap_1570 168 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 121604706 Common - propionate--CoA ligase Pnap_1804 219 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 121603206 Common - LrgB family protein Pnap_0291 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 121605671 Common - nitrogen metabolism transcriptional regulator, NtrC, Fis Family Pnap_2777 208 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 121605088 Common - Carboxymuconolactone decarboxylase Pnap_2188 96 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 121603851 Common - Hydantoinase B/oxoprolinase Pnap_0942 89 COG0146 HyuB, N-methylhydantoinase B/acetone carboxylase, alpha subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 121605497 Common - porin, Gram-negative type Pnap_2603 39 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 121604923 Common - band 7 protein Pnap_2022 221 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 121606542 Common - anthranilate synthase component I Pnap_3654 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 121604261 Common - porin, Gram-negative type Pnap_1354 15 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 121603928 Common - Uncharacterized protein UPF0065 Pnap_1019 67 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121603138 Common - protein of unknown function DUF445 Pnap_0221 49 COG2733 COG2733, Predicted membrane protein Function unknown 121605511 Common - Dihydroorotate oxidase Pnap_2617 227 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 121604533 Common - excinuclease ABC, C subunit Pnap_1627 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 121604572 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Pnap_1666 85 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 121605292 Common - ribosomal protein S18 Pnap_2393 214 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 121606953 Common putA trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase Pnap_4070 220 COG4230 COG4230, Delta 1-pyrroline-5-carboxylate dehydrogenase Energy production and conversion 121606949 Common - transcriptional regulator, RpiR family Pnap_4066 52 COG1737 RpiR, Transcriptional regulators Transcription 121603579 Common - Ferric reductase domain protein transmembrane component, N-terminal domain Pnap_0668 76 COG2717 COG2717, Predicted membrane protein Function unknown 121606806 Common - membrane protein of unknown function Pnap_3918 11 COG1950 COG1950, Predicted membrane protein Function unknown 121603215 Common - hypothetical protein Pnap_0300 8 None None None 121604650 Common - transposase IS116/IS110/IS902 family protein Pnap_1748 81 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 121606573 Common - pyruvate carboxyltransferase Pnap_3685 195 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 121602932 Common - Endonuclease/exonuclease/phosphatase Pnap_0014 66 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 121604323 Common - putative transporter signal peptide protein Pnap_1417 51 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 121604069 Common - hypothetical protein Pnap_1161 10 None None None 121606045 Nonpathogen - hypothetical protein Pnap_3155 3 None None None 121606865 Common - DNA binding domain, excisionase family Pnap_3978 26 None None None 121604754 Nonpathogen - hypothetical protein Pnap_1852 1 None None None 121606810 Nonpathogen - hypothetical protein Pnap_3922 1 None None None 121604048 Common - putative ATP-binding protein Pnap_1140 13 COG1106 COG1106, Predicted ATPases General function prediction only 121606513 Nonpathogen - hypothetical protein Pnap_3625 1 None None None 121606289 Common - rod shape-determining protein RodA Pnap_3400 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 121604346 Common - protein of unknown function DUF1178 Pnap_1440 46 COG5319 COG5319, Uncharacterized protein conserved in bacteria Function unknown 121605517 Common - putative uncharacterized conserved protein Pnap_2623 65 COG4301 COG4301, Uncharacterized conserved protein Function unknown 121606812 Common - DNA/RNA non-specific endonuclease Pnap_3924 40 COG1864 NUC1, DNA/RNA endonuclease G, NUC1 Nucleotide transport and metabolism 121606282 Common - Redoxin domain protein Pnap_3393 128 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 121606598 Common - RNA polymerase, sigma 54 subunit, RpoN Pnap_3710 145 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 121606323 Common - protein of unknown function DUF484 Pnap_3434 28 COG3159 COG3159, Uncharacterized protein conserved in bacteria Function unknown 121603136 Common - O-acetylhomoserine/O-acetylserine sulfhydrylase Pnap_0219 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 121602947 Common - sensory histidine kinase CreC Pnap_0029 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121603559 Nonpathogen - hypothetical protein Pnap_0648 1 None None None 121605911 Common - tryptophan 2,3-dioxygenase Pnap_3020 42 COG3483 TDO2, Tryptophan 2,3-dioxygenase (vermilion) Amino acid transport and metabolism 121604720 Common - peptide deformylase Pnap_1818 212 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 121606657 Common holA DNA polymerase III subunit delta Pnap_3769 70 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 121605551 Common - 3-oxoacid CoA-transferase, B subunit Pnap_2657 104 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 121605641 Common - protein of unknown function UPF0153 Pnap_2747 4 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 121603866 Common - chromosome segregation and condensation protein ScpA Pnap_0957 128 COG1354 COG1354, Uncharacterized conserved protein Function unknown 121605223 Common - nitrogen fixation protein NifX Pnap_2323 32 None None None 121603809 Common - 4-diphosphocytidyl-2C-methyl-D-erythritol kinase Pnap_0900 186 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 121604358 Common - hypothetical protein Pnap_1452 26 None None None 121606224 Common - seryl-tRNA synthetase Pnap_3335 245 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 121606955 Common - hypothetical protein Pnap_4072 15 None None None 121606389 Common - UbiA prenyltransferase Pnap_3500 61 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 121602996 Common - putative transposase, IS891/IS1136/IS1341 Pnap_0078 39 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 121603126 Common rpsC 30S ribosomal protein S3 Pnap_0209 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 121603292 Common - transcriptional regulator, XRE family Pnap_0377 10 None None None 121606456 Common - bifunctional enoyl-CoA hydratase/phosphate acetyltransferase Pnap_3568 161 COG0280 Pta, Phosphotransacetylase Energy production and conversion 121605255 Common - RNA polymerase sigma factor Pnap_2356 60 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 121606544 Common - phosphoglycolate phosphatase Pnap_3656 187 COG0546 Gph, Predicted phosphatases General function prediction only 121606108 Common - protein of unknown function DUF1653 Pnap_3218 34 COG4728 COG4728, Uncharacterized protein conserved in bacteria Function unknown 121606734 Common - peptidase M22, glycoprotease Pnap_3846 112 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 121603988 Common - hypothetical protein Pnap_1079 44 COG3577 COG3577, Predicted aspartyl protease General function prediction only 121603721 Common - DNA-directed RNA polymerase subunit omega Pnap_0810 112 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 121604354 Common - putative transcriptional regulator, MerR family Pnap_1448 30 COG0789 SoxR, Predicted transcriptional regulators Transcription 121605743 Common - phenylalanyl-tRNA synthetase, alpha subunit Pnap_2850 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 121606434 Common - AMP nucleosidase Pnap_3545 54 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 121604310 Common - molybdopterin oxidoreductase Pnap_1404 192 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 121603905 Common - ATP-dependent endonuclease of the OLD family Pnap_0996 50 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 121603802 Common - peptidase M16 domain protein Pnap_0893 160 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 121604679 Common - putative transmembrane protein Pnap_1777 5 None None None 121605980 Common - uroporphyrinogen III synthase Pnap_3089 18 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 121603552 Common - cobalamin-5-phosphate synthase CobS Pnap_0641 24 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 121606871 Common - Methyltransferase type 11 Pnap_3985 40 COG3963 COG3963, Phospholipid N-methyltransferase Lipid metabolism 121604099 Common - hypothetical protein Pnap_1192 4 None None None 121606088 Common - NusG antitermination factor Pnap_3198 30 COG0250 NusG, Transcription antiterminator Transcription 121603444 Common - BLUF domain protein Pnap_0531 37 None None None 121605832 Common - Enoyl-CoA hydratase/isomerase Pnap_2941 177 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 121605651 Common - CBS domain containing protein Pnap_2757 131 COG0517 COG0517, FOG: CBS domain General function prediction only 121604307 Common - hypothetical protein Pnap_1401 14 None None None 121604637 Common - protein of unknown function DUF163 Pnap_1733 165 COG1576 COG1576, Uncharacterized conserved protein Function unknown 121603547 Common - exsB protein Pnap_0636 161 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 121605361 Common - IstB domain protein ATP-binding protein Pnap_2464 96 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 121605839 Common - benzoate-CoA ligase family Pnap_2948 222 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 121606193 Common - phage tail protein I Pnap_3303 30 COG4385 gpI, Bacteriophage P2-related tail formation protein General function prediction only 121606687 Common - NAD(P) transhydrogenase, subunit alpha part 2 Pnap_3799 117 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 121605146 Common - putative transmembrane protein Pnap_2246 10 None None None 121605464 Common - MotA/TolQ/ExbB proton channel Pnap_2569 144 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 121603659 Common - gamma-glutamyl kinase Pnap_0748 194 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 121606977 Common - transposase, IS605 OrfB family Pnap_4095 69 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 121603160 Common - lipoate-protein ligase B Pnap_0243 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 121605287 Common - tRNA-dihydrouridine synthase A Pnap_2388 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 121604911 Common - ribosome-binding factor A Pnap_2010 156 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 121605347 Common - UBA/THIF-type NAD/FAD binding protein Pnap_2448 160 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 121606908 Nonpathogen - hypothetical protein Pnap_4024 3 None None None 121603460 Common - long-chain-fatty-acid--CoA ligase-related protein Pnap_0548 33 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 121603320 Common - conserved repeat domain Pnap_0405 11 None None None 121604216 Nonpathogen - hypothetical protein Pnap_1309 4 None None None 121605383 Common - aromatic-ring-hydroxylating dioxygenase, beta subunit Pnap_2487 14 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 121605592 Common - hypothetical protein Pnap_2698 30 COG2068 COG2068, Uncharacterized MobA-related protein General function prediction only 121605053 Common - precorrin-3B C17-methyltransferase Pnap_2153 194 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 121605556 Common - Catalase Pnap_2662 126 COG0753 KatE, Catalase Inorganic ion transport and metabolism 121606328 Common - short-chain dehydrogenase/reductase SDR Pnap_3439 169 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 121604248 Nonpathogen - hypothetical protein Pnap_1341 1 None None None 121604031 Common - pyruvate carboxyltransferase Pnap_1123 142 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 121605956 Common - protease Do Pnap_3065 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 121605485 Common - GCN5-related N-acetyltransferase Pnap_2590 28 COG0456 RimI, Acetyltransferases General function prediction only 121605895 Common - integral membrane protein MviN Pnap_3004 189 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 121603540 Common - phage integrase family protein Pnap_0629 9 None None None 121605794 Common - hypothetical protein Pnap_2903 14 None None None 121606837 Common - protein phosphatase 2C domain protein Pnap_3950 137 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 121603939 Common - ABC transporter related Pnap_1030 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 121604805 Common - ABC transporter related Pnap_1903 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 121606027 Common - extracellular solute-binding protein, family 1 Pnap_3137 124 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 121606716 Common - protein of unknown function DUF6, transmembrane Pnap_3828 27 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 121603094 Common - protein of unknown function DUF81 Pnap_0177 129 COG0730 COG0730, Predicted permeases General function prediction only 121603669 Common - hypothetical protein Pnap_0758 6 COG3149 PulM, Type II secretory pathway, component PulM Intracellular trafficking and secretion 121603149 Common - alpha amylase, catalytic region Pnap_0232 103 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 121603112 Common - ferredoxin-like protein Pnap_0195 91 COG3411 COG3411, Ferredoxin Energy production and conversion 121602987 Common - FAD linked oxidase domain protein Pnap_0069 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 121603298 Common - hypothetical protein Pnap_0383 4 None None None 121606987 Common - RNP-1 like RNA-binding protein Pnap_4105 66 COG0724 COG0724, RNA-binding proteins (RRM domain) General function prediction only 121606182 Common - phage small terminase subunit Pnap_3292 19 None None None 121603081 Common - ABC transporter related Pnap_0164 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 121603598 Common - Mammalian cell entry related domain protein Pnap_0687 85 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 121603671 Common - General secretion pathway protein K Pnap_0760 20 COG3156 PulK, Type II secretory pathway, component PulK Intracellular trafficking and secretion 121604747 Common - uncharacterized domain 1 Pnap_1845 58 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 121606464 Nonpathogen - hypothetical protein Pnap_3576 7 COG5164 SPT5, Transcription elongation factor Transcription 121606605 Common - cytidyltransferase-related domain Pnap_3717 100 COG1056 NadR, Nicotinamide mononucleotide adenylyltransferase Coenzyme metabolism 121605393 Common - type II secretion system protein E Pnap_2497 227 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 121606510 Common - thioesterase superfamily protein Pnap_3622 24 COG0824 FcbC, Predicted thioesterase General function prediction only 121605751 Common - binding-protein-dependent transport systems inner membrane component Pnap_2859 181 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 121603632 Common - 40-residue YVTN family beta-propeller repeat protein Pnap_0721 83 COG3391 COG3391, Uncharacterized conserved protein Function unknown 121605090 Nonpathogen - hypothetical protein Pnap_2190 2 None None None 121606117 Common - HNH endonuclease Pnap_3227 94 COG1403 McrA, Restriction endonuclease Defense mechanisms 121603029 Common - AAA ATPase, central domain protein Pnap_0112 246 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 121605758 Common - putative transcriptional regulator, GntR family Pnap_2866 203 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 121604749 Common - acyl-CoA dehydrogenase domain protein Pnap_1847 127 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 121606442 Nonpathogen - hypothetical protein Pnap_3554 1 None None None 121605017 Common - intradiol ring-cleavage dioxygenase Pnap_2116 47 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 121603708 Common - acetyl-CoA acetyltransferases Pnap_0797 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 121605048 Common - cobalamin biosynthesis protein CobD Pnap_2148 151 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 121602980 Nonpathogen - hypothetical protein Pnap_0062 4 COG4113 COG4113, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 121605277 Common - lactoylglutathione lyase Pnap_2378 21 None None None 121605020 Common - muconate and chloromuconate cycloisomerases Pnap_2119 135 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 121604455 Nonpathogen - hypothetical protein Pnap_1549 2 None None None 121605212 Common - nitrogen fixation protein NifW Pnap_2312 23 None None None 121604975 Common - polar amino acid ABC transporter, inner membrane subunit Pnap_2074 175 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 121605814 Common - Biopolymer transport protein ExbD/TolR Pnap_2923 130 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 121605480 Common - NADPH-dependent FMN reductase Pnap_2585 67 COG0431 COG0431, Predicted flavoprotein General function prediction only 121606165 Common - protein of unknown function DUF6, transmembrane Pnap_3275 84 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 121603678 Common - type II secretion system protein Pnap_0767 146 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 121605961 Common - beta-ketoacyl synthase Pnap_3070 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 121605670 Common - exodeoxyribonuclease III Xth Pnap_2776 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 121606787 Common - transcriptional regulator, TetR family Pnap_3899 12 COG1309 AcrR, Transcriptional regulator Transcription 121606970 Nonpathogen - hypothetical protein Pnap_4087 1 None None None 121606230 Common - response regulator receiver protein Pnap_3341 84 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 121604584 Common - Methyltransferase type 11 Pnap_1679 71 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 121605219 Common - NifQ family protein Pnap_2319 23 None None None 121605379 Common - 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase Pnap_2483 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 121605408 Common - cytochrome c biogenesis protein, transmembrane region Pnap_2512 196 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 121603228 Common - YiaAB two helix domain protein Pnap_0313 14 COG4298 COG4298, Uncharacterized protein conserved in bacteria Function unknown 121606492 Common - potassium-transporting ATPase, A subunit Pnap_3604 96 COG2060 KdpA, K+-transporting ATPase, A chain Inorganic ion transport and metabolism 121604695 Nonpathogen - hypothetical protein Pnap_1793 2 None None None 121606693 Common - protein of unknown function DUF453 Pnap_3805 91 COG2828 COG2828, Uncharacterized protein conserved in bacteria Function unknown 121605695 Common - ADP-L-glycero-D-manno-heptose-6-epimerase Pnap_2801 213 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 121604819 Nonpathogen - hypothetical protein Pnap_1917 2 None None None 121603506 Common - phage Tail Collar domain protein Pnap_0595 33 COG4675 MdpB, Microcystin-dependent protein Function unknown 121606778 Nonpathogen - hypothetical protein Pnap_3890 7 None None None 121603327 Common - phospholipase D/Transphosphatidylase Pnap_0412 111 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 121603012 Common - chromosome replication initiation inhibitor protein Pnap_0095 88 COG0583 LysR, Transcriptional regulator Transcription 121604672 Common - acyl-(acyl-carrier-protein)--UDP-N-acetylglucosamine O-acyltransferase Pnap_1770 147 COG1043 LpxA, Acyl- acyl carrier protein 121606372 Common - glycosyl transferase, group 1 Pnap_3483 203 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 121605999 Common - transposase IS116/IS110/IS902 family protein Pnap_3108 76 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 121606382 Common - histone family protein nucleoid-structuring protein H-NS Pnap_3493 30 COG2916 Hns, DNA-binding protein H-NS General function prediction only 121604866 Common - hypothetical protein Pnap_1965 15 COG3259 FrhA, Coenzyme F420-reducing hydrogenase, alpha subunit Energy production and conversion 121606993 Common - cyclic nucleotide-binding protein Pnap_4111 7 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 121605823 Common - transcriptional regulator, LysR family Pnap_2932 124 COG0583 LysR, Transcriptional regulator Transcription 121606379 Common - dTDP-4-dehydrorhamnose reductase Pnap_3490 173 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 121606878 Nonpathogen - Collagen triple helix repeat Pnap_3992 1 None None None 121604874 Common - HupE/UreJ protein Pnap_1973 40 COG2370 HupE, Hydrogenase/urease accessory protein Posttranslational modification, protein turnover, chaperones 121603078 Common - NADH:flavin oxidoreductase/NADH oxidase Pnap_0161 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 121606101 Common - cell divisionFtsK/SpoIIIE Pnap_3211 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 121605109 Common - Ppx/GppA phosphatase Pnap_2209 180 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 121603693 Common - import inner membrane translocase, subunit Tim44 Pnap_0782 32 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 121604497 Common - NAD-dependent epimerase/dehydratase Pnap_1591 78 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 121602972 Nonpathogen - hypothetical protein Pnap_0054 1 None None None 121604775 Common - histidyl-tRNA synthetase Pnap_1873 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 121604201 Common - transposase, IS605 OrfB family Pnap_1294 76 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 121603666 Common - general secretory pathway protein E Pnap_0755 214 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 121603973 Common - protein of unknown function DUF404 Pnap_1064 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 121605368 Common - transposase IS3/IS911 family protein Pnap_2471 18 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 121606962 Common - amidohydrolase 2 Pnap_4079 48 COG3618 COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 121606586 Common - Lysine exporter protein (LYSE/YGGA) Pnap_3698 74 COG1279 COG1279, Lysine efflux permease General function prediction only 121603252 Common rpsE 30S ribosomal protein S5 Pnap_0337 247 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 121603285 Common - protein of unknown function, ATP binding Pnap_0370 25 COG2229 COG2229, Predicted GTPase General function prediction only 121605509 Common - glutaredoxin Pnap_2615 11 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 121606750 Common - phosphoribosylaminoimidazole carboxylase, ATPase subunit Pnap_3862 191 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 121605901 Common - hypothetical protein Pnap_3010 19 None None None 121603271 Common - Transthyretin Pnap_0356 63 COG2351 COG2351, Transthyretin-like protein General function prediction only 121603528 Common - Uncharacterized protein UPF0065 Pnap_0617 74 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121603637 Common - Pyrrolo-quinoline quinone Pnap_0726 74 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 121604028 Common - 4-hydroxyphenylpyruvate dioxygenase Pnap_1120 78 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 121606671 Common - cytochrome oxidase maturation protein, cbb3-type Pnap_3783 8 COG3197 FixS, Uncharacterized protein, possibly involved in nitrogen fixation Inorganic ion transport and metabolism 121605165 Common - hypothetical protein Pnap_2265 5 None None None 121605015 Common - transcriptional regulator, LysR family Pnap_2114 193 COG0583 LysR, Transcriptional regulator Transcription 121605971 Common - maf protein Pnap_3080 186 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 121603242 Common - pyrroline-5-carboxylate reductase Pnap_0327 212 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 121604424 Nonpathogen - hypothetical protein Pnap_1518 15 None None None 121605949 Common - pyridoxal phosphate biosynthetic protein PdxJ Pnap_3058 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 121604289 Common - molybdenum cofactor synthesis domain Pnap_1383 139 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 121604685 Common - 20S proteasome, A and B subunits Pnap_1783 7 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 121606507 Common - enoyl-CoA hydratase Pnap_3619 168 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 121604038 Common - Glucarate dehydratase Pnap_1130 54 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 121604335 Common - NADH-quinone oxidoreductase, F subunit Pnap_1429 162 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 121604090 Common - Septum formation initiator Pnap_1182 61 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 121605843 Common - inner-membrane translocator Pnap_2952 122 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 121603400 Common - Extracellular ligand-binding receptor Pnap_0487 127 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 121604403 Common - putative transmembrane protein Pnap_1497 83 None None None 121603177 Common - hypothetical protein Pnap_0260 16 COG4319 COG4319, Ketosteroid isomerase homolog Function unknown 121605136 Nonpathogen - hypothetical protein Pnap_2236 1 None None None 121603725 Common - protein phosphatase 2C domain protein Pnap_0814 128 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 121604405 Common - exodeoxyribonuclease VII, small subunit Pnap_1499 86 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 121604072 Common - acetone carboxylase gamma subunit-like protein Pnap_1164 20 COG4647 AcxC, Acetone carboxylase, gamma subunit Secondary metabolites biosynthesis, transport, and catabolism 121604179 Common - UspA domain protein Pnap_1272 117 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 121606729 Common - thioesterase superfamily protein Pnap_3841 140 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 121606447 Common - TRAP-type uncharacterized transport system protein, periplasmic component Pnap_3559 46 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 121606621 Common - 4-oxalocrotonate tautomerase Pnap_3733 37 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 121605935 Common - tRNA pseudouridine synthase A Pnap_3044 234 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 121606420 Common - inner-membrane translocator Pnap_3531 125 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 121603461 Common - ABC transporter related Pnap_0549 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 121605890 Common - transcriptional regulator, XRE family Pnap_2999 27 COG5606 COG5606, Uncharacterized conserved small protein Function unknown 121605412 Nonpathogen - late embryogenesis abundant protein Pnap_2516 1 None None None 121606296 Common - shikimate 5-dehydrogenase Pnap_3407 200 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 121603585 Common - Pilus assembly protein, PilO Pnap_0674 47 COG3167 PilO, Tfp pilus assembly protein PilO Cell motility and secretion / Intracellular trafficking and secretion 121603791 Common - cytochrome c oxidase, subunit III Pnap_0882 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 121604812 Common - transposase and inactivated derivative Pnap_1910 7 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 121603748 Common - formate dehydrogenase, subunit FdhD Pnap_0839 129 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 121605992 Nonpathogen - hypothetical protein Pnap_3101 1 None None None 121606679 Common - ferric uptake regulator, Fur family Pnap_3791 195 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 121606830 Common - O-antigen polymerase Pnap_3942 13 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 121602962 Common - TRAP dicarboxylate transporter, DctM subunit Pnap_0044 120 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 121604208 Common - methyltransferase small Pnap_1301 80 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 121604492 Common - hypothetical protein Pnap_1586 18 None None None 121602975 Common - histone deacetylase superfamily Pnap_0057 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 121603591 Common - deoxyguanosinetriphosphate triphosphohydrolase-like protein Pnap_0680 160 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 121605806 Common - riboflavin biosynthesis protein RibD Pnap_2915 229 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 121605500 Common - RbsD or FucU transport Pnap_2606 30 COG4154 FucU, Fucose dissimilation pathway protein FucU Carbohydrate transport and metabolism 121603871 Nonpathogen - hypothetical protein Pnap_0962 2 None None None 121603646 Common - GAF modulated sigma54 specific transcriptional regulator, Fis family Pnap_0735 177 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 121606528 Common - DNA-directed RNA polymerase, beta subunit Pnap_3640 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 121603469 Common - Acyl-CoA dehydrogenase, type 2, C-terminal domain Pnap_0557 83 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 121606425 Common - binding-protein-dependent transport systems inner membrane component Pnap_3536 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 121603260 Common - DNA-directed RNA polymerase subunit alpha Pnap_0345 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 121606174 Common - MaoC domain protein dehydratase Pnap_3284 105 COG2030 MaoC, Acyl dehydratase Lipid metabolism 121603901 Common - Ethyl tert-butyl ether degradation EthD Pnap_0992 11 None None None 121605526 Common - extracellular solute-binding protein, family 1 Pnap_2632 71 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 121604256 Nonpathogen - hypothetical protein Pnap_1349 2 None None None 121604397 Common - polar amino acid ABC transporter, inner membrane subunit Pnap_1491 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 121606307 Common - cell division protein FtsW Pnap_3418 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 121605926 Common - succinate dehydrogenase and fumarate reductase iron-sulfur protein Pnap_3035 204 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 121605041 Common - L-carnitine dehydratase/bile acid-inducible protein F Pnap_2141 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 121604581 Nonpathogen - hypothetical protein Pnap_1676 1 None None None 121606009 Common - glycosyl transferase, group 1 Pnap_3119 104 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 121603478 Common - RND efflux system, outer membrane lipoprotein, NodT family Pnap_0566 111 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 121605815 Common - TonB family protein Pnap_2924 12 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 121604871 Common - hydrogenase assembly chaperone hypC/hupF Pnap_1970 14 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 121603494 Common - Tetratricopeptide TPR_2 repeat protein Pnap_0582 22 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 121603171 Common - ATP synthase F1, gamma subunit Pnap_0254 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 121603838 Common - glutaredoxin 3 Pnap_0929 119 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 121603032 Common - homocysteine S-methyltransferase Pnap_0115 165 COG0646 MetH, Methionine synthase I (cobalamin-dependent), methyltransferase domain Amino acid transport and metabolism 121603405 Common - rare lipoprotein A Pnap_0492 135 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 121605708 Common - Antibiotic biosynthesis monooxygenase Pnap_2814 31 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 121604789 Common - tRNA 2-selenouridine synthase Pnap_1887 65 COG2603 COG2603, Predicted ATPase General function prediction only 121604846 Common - Alpha/beta hydrolase fold-3 domain protein Pnap_1944 137 COG0657 Aes, Esterase/lipase Lipid metabolism 121603616 Common - histidine triad (HIT) protein Pnap_0705 232 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 121604909 Common - GTP-binding protein TypA Pnap_2008 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 121604073 Common - 5-oxoprolinase (ATP-hydrolyzing) Pnap_1165 116 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 121604021 Common - short-chain dehydrogenase/reductase SDR Pnap_1113 190 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 121604195 Common - hypothetical protein Pnap_1288 3 COG4575 ElaB, Uncharacterized conserved protein Function unknown 121604298 Common - cell divisionFtsK/SpoIIIE Pnap_1392 66 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 121604158 Nonpathogen - hypothetical protein Pnap_1251 2 None None None 121603129 Common - ribosomal protein S17 Pnap_0212 224 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 121606037 Common - maleylacetoacetate isomerase Pnap_3147 75 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 121606762 Common pgk phosphoglycerate kinase Pnap_3874 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 121604707 Common - ISSod10, transposase OrfB Pnap_1805 26 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 121606094 Common - CDP-6-deoxy-delta-3,4-glucoseen reductase Pnap_3204 142 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 121605688 Common - Prephenate dehydrogenase Pnap_2794 160 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 121604043 Common - peptide methionine sulfoxide reductase Pnap_1135 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 121604767 Common - pseudouridine synthase, RluA family Pnap_1865 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 121604529 Common - protein of unknown function DUF195 Pnap_1623 119 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 121604730 Common - hypothetical protein Pnap_1828 19 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 121604333 Common - NADH dehydrogenase subunit D Pnap_1427 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 121604935 Common - transcriptional regulator, LysR family Pnap_2034 188 COG0583 LysR, Transcriptional regulator Transcription 121606570 Common - PilT protein domain protein Pnap_3682 42 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 121605359 Common - Rieske (2Fe-2S) domain protein Pnap_2461 93 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 121603340 Common - transposase IS116/IS110/IS902 family protein Pnap_0426 81 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 121604166 Common - protein of unknown function DUF411 Pnap_1259 64 COG3019 COG3019, Predicted metal-binding protein General function prediction only 121605983 Nonpathogen - hypothetical protein Pnap_3092 1 None None None 121605763 Common - Uncharacterized protein UPF0065 Pnap_2872 70 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121604880 Common - transcriptional regulator, LysR family Pnap_1979 192 COG0583 LysR, Transcriptional regulator Transcription 121605937 Common - tryptophan synthase subunit beta Pnap_3046 226 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 121603457 Common - binding-protein-dependent transport systems inner membrane component Pnap_0545 141 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 121606919 Nonpathogen - hypothetical protein Pnap_4036 1 None None None 121604471 Common - Fe-S protein assembly chaperone HscA Pnap_1565 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 121603294 Common - protein of unknown function DUF167 Pnap_0379 32 COG1872 COG1872, Uncharacterized conserved protein Function unknown 121604825 Common - tetraacyldisaccharide 4'-kinase Pnap_1923 120 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 121606010 Common - glycosyl transferase, group 1 Pnap_3120 99 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 121604944 Common - protein of unknown function DUF255 Pnap_2043 105 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 121603103 Common - multiple antibiotic resistance (MarC)-related proteins Pnap_0186 158 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 121605859 Common - efflux transporter, RND family, MFP subunit Pnap_2968 158 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 121605732 Nonpathogen - hypothetical protein Pnap_2838 15 None None None 121606708 Common - Cl- channel, voltage-gated family protein Pnap_3820 128 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 121603381 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Pnap_0467 65 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 121604443 Common - protein of unknown function DUF125, transmembrane Pnap_1537 63 COG1814 COG1814, Uncharacterized membrane protein Function unknown 121606749 Common - Sua5/YciO/YrdC/YwlC family protein Pnap_3861 234 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 121604700 Common - hypothetical protein Pnap_1798 29 None None None 121605319 Common - aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein Pnap_2420 103 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 121604600 Common - thioesterase superfamily protein Pnap_1695 136 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 121604618 Common - RDD domain containing protein Pnap_1713 24 COG1714 COG1714, Predicted membrane protein/domain Function unknown 121604591 Nonpathogen - hypothetical protein Pnap_1686 2 None None None 121606857 Common - NnrS family protein Pnap_3970 58 COG3213 NnrS, Uncharacterized protein involved in response to NO Inorganic ion transport and metabolism 121604546 Nonpathogen - hypothetical protein Pnap_1640 5 None None None 121605152 Common - putative RecA/RadA recombinase Pnap_2252 11 COG5471 COG5471, Uncharacterized conserved protein Function unknown 121605667 Common - Dihydrofolate reductase Pnap_2773 145 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 121605159 Common - hypothetical protein Pnap_2259 8 None None None 121604530 Common - conserved hypothetical protein 730 Pnap_1624 111 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 121606237 Common - protein of unknown function DUF179 Pnap_3348 129 COG1678 COG1678, Putative transcriptional regulator Transcription 121606531 Common rplA 50S ribosomal protein L1 Pnap_3643 244 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 121603410 Common - regulator of RNA terminal phosphate cyclase Pnap_0497 163 COG4650 RtcR, Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain Transcription / Signal transduction mechanisms 121603706 Nonpathogen - hypothetical protein Pnap_0795 2 None None None 121605038 Common - Uncharacterized protein UPF0065 Pnap_2138 69 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121606044 Common - L-lactate dehydrogenase (cytochrome) Pnap_3154 115 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 121605496 Common - periplasmic binding protein/LacI transcriptional regulator Pnap_2602 71 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 121606667 Common - cytochrome c oxidase, cbb3-type, subunit III Pnap_3779 79 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 121606938 Common - glyceraldehyde-3-phosphate dehydrogenase, type I Pnap_4055 218 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 121605245 Common - globin Pnap_2346 65 COG2346 COG2346, Truncated hemoglobins General function prediction only 121603604 Common - BolA family protein Pnap_0693 110 COG5007 COG5007, Predicted transcriptional regulator, BolA superfamily Transcription 121605854 Common - ATP-dependent DNA helicase, RecQ family Pnap_2963 229 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 121604954 Common - O-antigen polymerase Pnap_2053 9 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 121604737 Common - methionine-R-sulfoxide reductase Pnap_1835 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 121605160 Common - hypothetical protein Pnap_2260 4 None None None 121606078 Common - Exopolysaccharide biosynthesis protein-like protein Pnap_3188 3 COG5039 COG5039, Exopolysaccharide biosynthesis protein Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 121606305 Common murC UDP-N-acetylmuramate--L-alanine ligase Pnap_3416 209 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 121606479 Nonpathogen - hypothetical protein Pnap_3591 1 None None None 121605196 Common - DSBA oxidoreductase Pnap_2296 83 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 121606554 Common - phosphatidylglycerophosphatase A Pnap_3666 95 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 121604433 Common - GrpE protein Pnap_1527 210 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 121605298 Common - phosphoenolpyruvate synthase Pnap_2399 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 121605457 Common - protein of unknown function DUF1111 Pnap_2562 50 COG3488 COG3488, Predicted thiol oxidoreductase Energy production and conversion 121606247 Common - phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase Pnap_3358 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 121606850 Common - DNA topoisomerase III Pnap_3963 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 121604012 Common - glycogen debranching enzyme GlgX Pnap_1103 146 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 121603611 Common - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase Pnap_0700 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 121606000 Common - hypothetical protein Pnap_3109 3 None None None 121605865 Common - Haloacid dehalogenase domain protein hydrolase Pnap_2974 5 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 121603623 Common - large conductance mechanosensitive channel protein Pnap_0712 144 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 121606796 Common - iron-containing alcohol dehydrogenase Pnap_3908 160 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 121603223 Common - hypothetical protein Pnap_0308 12 None None None 121606137 Common - von Willebrand factor, type A Pnap_3247 29 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 121603147 Common - binding-protein-dependent transport systems inner membrane component Pnap_0230 183 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 121606895 Common - Exoribonuclease II Pnap_4011 191 COG0557 VacB, Exoribonuclease R Transcription 121603303 Nonpathogen - hypothetical protein Pnap_0388 3 None None None 121604784 Common - tRNA synthetase, class II (G, H, P and S) Pnap_1882 148 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 121605471 Common rumA 23S rRNA 5-methyluridine methyltransferase Pnap_2576 198 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 121603910 Nonpathogen - hypothetical protein Pnap_1001 1 None None None 121606271 Common - integral membrane sensor signal transduction histidine kinase Pnap_3382 186 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121603396 Nonpathogen - transport-associated Pnap_0482 1 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 121603788 Common - Cytochrome-c oxidase Pnap_0879 171 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 121604377 Common - DEAD/DEAH box helicase domain protein Pnap_1471 229 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 121604573 Common - hypothetical protein Pnap_1668 36 COG5501 COG5501, Predicted secreted protein Function unknown 121606294 Common - ribonuclease II Pnap_3405 56 COG0557 VacB, Exoribonuclease R Transcription 121603204 Common - hypothetical protein Pnap_0289 3 None None None 121605265 Common - periplasmic binding protein Pnap_2366 115 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 121602938 Common - glycine oxidase ThiO Pnap_0020 64 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 121606691 Common - NUDIX hydrolase Pnap_3803 48 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 121603361 Common - phospholipid/glycerol acyltransferase Pnap_0447 186 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 121605120 Common - heat shock protein DnaJ domain protein Pnap_2220 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 121605002 Common - AIR synthase related protein Pnap_2101 79 COG2144 COG2144, Selenophosphate synthetase-related proteins General function prediction only 121604483 Common - hypothetical protein Pnap_1577 10 None None None 121606821 Nonpathogen - hypothetical protein Pnap_3933 1 None None None 121604607 Common - Inorganic diphosphatase Pnap_1702 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 121605870 Common - uncharacterized domain 1 Pnap_2979 58 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 121605600 Common - Shikimate dehydrogenase Pnap_2706 88 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 121604663 Common - ribosome recycling factor Pnap_1761 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 121605100 Common - PAS/PAC sensor signal transduction histidine kinase Pnap_2200 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 121605167 Common - hypothetical protein Pnap_2267 4 None None None 121604432 Common - chaperone protein DnaK Pnap_1526 234 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 121606843 Common - recA protein Pnap_3956 222 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 121605336 Common - protein of unknown function YGGT Pnap_2437 25 COG0762 COG0762, Predicted integral membrane protein Function unknown 121606311 Common - UDP-N-acetylmuramyl-tripeptide synthetases Pnap_3422 209 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 121604224 Nonpathogen - hypothetical protein Pnap_1317 1 None None None 121604661 Common - translation elongation factor Ts Pnap_1759 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 121605124 Common - Allergen V5/Tpx-1 family protein Pnap_2224 7 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 121606470 Common - predicted kinase Pnap_3582 50 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 121604570 Nonpathogen - hypothetical protein Pnap_1664 1 None None None 121603927 Common - Hydroxypyruvate reductase Pnap_1018 86 COG2379 GckA, Putative glycerate kinase Carbohydrate transport and metabolism 121605305 Common - putative poly-gamma-glutamate biosynthesis enzyme Pnap_2406 76 COG2843 PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) Cell envelope biogenesis, outer membrane 121606127 Common - protein of unknown function DUF112, transmembrane Pnap_3237 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 121603531 Common - GAF modulated sigma54 specific transcriptional regulator, Fis family Pnap_0620 170 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 121605712 Common rdgC recombination associated protein Pnap_2818 53 COG2974 RdgC, DNA recombination-dependent growth factor C DNA replication, recombination, and repair 121603415 Common - iron-sulfur cluster assembly accessory protein Pnap_0502 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 121604512 Common - putative ribonuclease BN Pnap_1606 9 COG1295 Rbn, Predicted membrane protein Function unknown 121605372 Common - Cupin 2, conserved barrel domain protein Pnap_2476 28 COG3435 COG3435, Gentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 121603310 Common - L-sorbosone dehydrogenase Pnap_0395 74 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 121606195 Nonpathogen - hypothetical protein Pnap_3305 1 None None None 121603730 Common - ATP-dependent protease La Pnap_0819 231 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 121605636 Common - hypothetical protein Pnap_2742 112 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 121604087 Common - Hsp33 protein Pnap_1179 132 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 121604214 Common - phospholipase/Carboxylesterase Pnap_1307 98 COG0400 COG0400, Predicted esterase General function prediction only 121603317 Common - protein of unknown function DUF6, transmembrane Pnap_0402 54 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 121604177 Common - hypothetical protein Pnap_1270 8 None None None 121603056 Common - metallophosphoesterase Pnap_0139 76 COG0622 COG0622, Predicted phosphoesterase General function prediction only 121603713 Common - ABC transporter related Pnap_0802 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 121604963 Common - protein of unknown function DUF937 Pnap_2062 33 COG3753 COG3753, Uncharacterized protein conserved in bacteria Function unknown 121606801 Common - Glutathione S-transferase, N-terminal domain Pnap_3913 97 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 121606436 Common - efflux transporter, RND family, MFP subunit Pnap_3548 151 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 121606991 Common - sodium/hydrogen exchanger Pnap_4109 174 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 121606775 Common - indolepyruvate ferredoxin oxidoreductase Pnap_3887 90 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 121606742 Common - iron permease FTR1 Pnap_3854 57 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 121604628 Common - regulatory proteins, IclR Pnap_1723 121 COG1414 IclR, Transcriptional regulator Transcription 121603155 Common - Phosphotransferase system, phosphocarrier protein HPr Pnap_0238 132 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 121606258 Common - Enoyl-CoA hydratase/isomerase Pnap_3369 187 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 121604146 Nonpathogen - hypothetical protein Pnap_1239 3 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 121604463 Common - TRAP dicarboxylate transporter, DctM subunit Pnap_1557 122 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 121603694 Common - hypothetical protein Pnap_0783 16 COG3165 COG3165, Uncharacterized protein conserved in bacteria Function unknown 121604635 Common - coproporphyrinogen III oxidase Pnap_1730 113 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 121604019 Common - Three-deoxy-D-manno-octulosonic-acid transferase domain protein Pnap_1110 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 121606504 Common - hypothetical protein Pnap_3616 32 COG4340 COG4340, Uncharacterized protein conserved in bacteria Function unknown 121606356 Common - Glutathione S-transferase, N-terminal domain Pnap_3467 94 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 121605913 Common - band 7 protein Pnap_3022 40 COG2268 COG2268, Uncharacterized protein conserved in bacteria Function unknown 121606336 Common - hypothetical protein Pnap_3447 27 COG3109 ProQ, Activator of osmoprotectant transporter ProP Signal transduction mechanisms 121605547 Nonpathogen - hypothetical protein Pnap_2653 2 None None None 121602956 Common - hypothetical protein Pnap_0038 40 COG3665 COG3665, Uncharacterized conserved protein Function unknown 121603066 Common - lipopolysaccharide heptosyltransferase II Pnap_0149 111 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 121604655 Common - ISCc1, transposase OrfB Pnap_1753 55 None None None 121605363 Common - transcriptional regulator, GntR family Pnap_2466 126 COG1802 GntR, Transcriptional regulators Transcription 121605445 Common - transcription-repair coupling factor Pnap_2550 234 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 121604068 Common - cobalamin synthesis protein, P47K Pnap_1160 125 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 121605585 Common - cytochrome c family protein Pnap_2691 10 None None None 121603755 Common - protein of unknown function DUF214 Pnap_0846 86 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 121606714 Common - integral membrane sensor signal transduction histidine kinase Pnap_3826 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121604523 Common - ABC transporter related Pnap_1617 244 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 121606120 Common - lipoprotein signal peptidase Pnap_3230 197 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 121603115 Common rpsL 30S ribosomal protein S12 Pnap_0198 243 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 121605573 Common - Electron-transferring-flavoprotein dehydrogenase Pnap_2679 106 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 121604276 Common - hypothetical protein Pnap_1369 14 COG4706 COG4706, Predicted 3-hydroxylacyl-(acyl carrier protein) dehydratase Lipid metabolism 121605272 Common - SWIB/MDM2 domain protein Pnap_2373 16 COG5531 COG5531, SWIB-domain-containing proteins implicated in chromatin remodeling Chromatin structure and dynamics 121603761 Common - CsbD family protein Pnap_0852 55 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 121604452 Common - sulfate ABC transporter, ATPase subunit Pnap_1546 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 121603508 Common - hypothetical protein Pnap_0597 2 None None None 121605578 Common - glycine cleavage system H protein Pnap_2684 188 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 121606637 Common - K+ potassium transporter Pnap_3749 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 121604640 Common - polysaccharide deacetylase Pnap_1736 88 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 121603786 Common - putative transmembrane protein Pnap_0877 5 COG5488 COG5488, Integral membrane protein Function unknown 121603944 Common - molybdopterin dehydrogenase, FAD-binding Pnap_1035 112 COG4630 XdhA, Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A Nucleotide transport and metabolism 121605019 Common - Muconolactone delta-isomerase Pnap_2118 24 COG4829 CatC1, Muconolactone delta-isomerase Secondary metabolites biosynthesis, transport, and catabolism 121606808 Common - molybdenum cofactor biosynthesis protein C Pnap_3920 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 121603683 Nonpathogen - hypothetical protein Pnap_0772 2 None None None 121603511 Common - Dimethylmenaquinone methyltransferase Pnap_0600 96 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 121606266 Common mdoG glucan biosynthesis protein G Pnap_3377 50 COG3131 MdoG, Periplasmic glucans biosynthesis protein Inorganic ion transport and metabolism 121605665 Common - FAD linked oxidase domain protein Pnap_2771 199 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 121605078 Common - hypothetical protein Pnap_2178 4 None None None 121604677 Common - carbamoyl-phosphate synthase, large subunit Pnap_1775 234 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 121605647 Nonpathogen - hypothetical protein Pnap_2753 2 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 121604505 Common - alpha-dehydro-beta-deoxy-D-glucarate aldolase Pnap_1599 74 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 121606646 Common - respiratory nitrate reductase, gamma subunit Pnap_3758 55 COG2181 NarI, Nitrate reductase gamma subunit Energy production and conversion 121603822 Common - BLUF domain protein Pnap_0913 42 None None None 121606644 Common - Carbonate dehydratase Pnap_3756 151 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 121604049 Common - putative signal-transduction protein with CBS domains Pnap_1141 168 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 121604388 Common - putative thiol-disulphide oxidoreductase DCC Pnap_1482 24 COG3011 COG3011, Uncharacterized protein conserved in bacteria Function unknown 121603352 Common - GCN5-related N-acetyltransferase Pnap_0438 16 COG3981 COG3981, Predicted acetyltransferase General function prediction only 121603378 Common - protein of unknown function DUF1326 Pnap_0464 16 COG5588 COG5588, Uncharacterized conserved protein Function unknown 121603966 Common - protein of unknown function, zinc metallopeptidase putative Pnap_1057 86 COG2321 COG2321, Predicted metalloprotease General function prediction only 121605131 Common - homoserine dehydrogenase Pnap_2231 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 121606058 Nonpathogen - hypothetical protein Pnap_3168 14 None None None 121604999 Common - FAD dependent oxidoreductase Pnap_2098 63 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 121604229 Nonpathogen - hypothetical protein Pnap_1322 3 None None None 121605567 Common - phosphopantetheine-binding Pnap_2673 13 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 121605238 Common - hypothetical protein Pnap_2339 3 None None None 121605025 Common - naphthoate synthase Pnap_2124 178 COG0447 MenB, Dihydroxynaphthoic acid synthase Coenzyme metabolism 121606154 Common - hypothetical protein Pnap_3264 34 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 121603076 Nonpathogen - hypothetical protein Pnap_0159 1 None None None 121604419 Common - nuclear export factor GLE1 Pnap_1513 27 COG4549 COG4549, Uncharacterized protein conserved in bacteria Function unknown 121604539 Common - histone family protein DNA-binding protein Pnap_1633 210 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 121605566 Common - beta-ketoacyl synthase Pnap_2672 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 121604241 Common - putative lipoprotein Pnap_1334 13 None None None 121605886 Nonpathogen - hypothetical protein Pnap_2995 1 None None None 121603003 Common - ABC transporter related Pnap_0086 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 121603481 Common - cytochrome c, class II Pnap_0569 15 COG3909 COG3909, Cytochrome c556 Energy production and conversion 121604981 Common - PfkB domain protein Pnap_2080 103 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 121603990 Common - UDP-N-acetylenolpyruvoylglucosamine reductase Pnap_1081 176 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 121605204 Common - efflux transporter, RND family, MFP subunit Pnap_2304 91 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 121604058 Common - protein of unknown function DUF486 Pnap_1150 53 COG3169 COG3169, Uncharacterized protein conserved in bacteria Function unknown 121604852 Common - hydrolase, TatD family Pnap_1951 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 121605138 Nonpathogen - hypothetical protein Pnap_2238 1 None None None 121604129 Common - MscS Mechanosensitive ion channel Pnap_1222 193 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 121603886 Common ureA urease subunit gamma Pnap_0977 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 121606278 Common - MJ0042 family finger-like protein Pnap_3389 18 None None None 121606025 Nonpathogen - putative methyl-accepting chemotaxis sensory transducer Pnap_3135 1 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 121605780 Common - aspartate kinase Pnap_2889 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 121605260 Common - DoxX family protein Pnap_2361 10 COG2259 COG2259, Predicted membrane protein Function unknown 121604116 Common - Alkaline phosphatase Pnap_1209 56 COG3540 PhoD, Phosphodiesterase/alkaline phosphatase D Inorganic ion transport and metabolism 121604184 Common - hypothetical protein Pnap_1277 37 COG4628 COG4628, Uncharacterized conserved protein Function unknown 121606579 Common - binding-protein-dependent transport systems inner membrane component Pnap_3691 143 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 121606240 Common - methyl-accepting chemotaxis sensory transducer Pnap_3351 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 121603438 Common - glycoside hydrolase 15-related Pnap_0525 68 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 121604837 Common sbcB exonuclease I Pnap_1935 52 COG2925 SbcB, Exonuclease I DNA replication, recombination, and repair 121603358 Common - Glycine--tRNA ligase Pnap_0444 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 121606940 Common - Nucleotidyl transferase Pnap_4057 168 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 121606130 Common - hypothetical protein Pnap_3240 33 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 121603763 Nonpathogen - hypothetical protein Pnap_0854 1 None None None 121604136 Common - Carboxylesterase Pnap_1229 93 COG0627 COG0627, Predicted esterase General function prediction only 121604670 Common - UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase Pnap_1768 157 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 121606926 Common - TRAP dicarboxylate transporter, DctP subunit Pnap_4043 103 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 121603367 Common - putative transcriptional regulator, MerR family Pnap_0453 48 COG0789 SoxR, Predicted transcriptional regulators Transcription 121605540 Nonpathogen - hypothetical protein Pnap_2646 1 None None None 121603013 Common - Extracellular ligand-binding receptor Pnap_0096 138 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 121604898 Common - CMP/dCMP deaminase, zinc-binding Pnap_1997 207 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 121603267 Common - UvrD/REP helicase Pnap_0352 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 121605042 Common - acyl-CoA dehydrogenase domain protein Pnap_2142 159 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 121603334 Common - transposase IS116/IS110/IS902 family protein Pnap_0420 76 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 121606226 Common - hydroxymethylbutenyl pyrophosphate reductase Pnap_3337 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 121603955 Common - 6-pyruvoyl tetrahydropterin synthase and hypothetical protein Pnap_1046 76 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 121604906 Common smpB SsrA-binding protein Pnap_2005 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 121605062 Common - cobalamin (vitamin B12) biosynthesis CbiX protein Pnap_2162 74 COG2138 COG2138, Uncharacterized conserved protein Function unknown 121603345 Common - beta-lactamase domain protein Pnap_0431 58 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 121603109 Common - delta-aminolevulinic acid dehydratase Pnap_0192 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 121606583 Common - glucokinase Pnap_3695 89 COG0837 Glk, Glucokinase Carbohydrate transport and metabolism 121605728 Common - Rhodanese domain protein Pnap_2834 156 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 121602994 Common - uracil-xanthine permease Pnap_0076 121 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 121606982 Common - chromate transporter, chromate ion transporter (CHR) family Pnap_4100 114 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 121605784 Common - cysteinyl-tRNA synthetase Pnap_2893 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 121603278 Common - uroporphyrinogen decarboxylase Pnap_0363 181 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 121602964 Common - carbohydrate kinase, thermoresistant glucokinase family Pnap_0046 80 COG3265 GntK, Gluconate kinase Carbohydrate transport and metabolism 121604426 Common - multiple resistance and pH regulation protein F Pnap_1520 58 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 121604064 Common - hypothetical protein Pnap_1156 97 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 121605345 Common - UvrD/REP helicase Pnap_2446 228 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 121605958 Common - anti sigma-E protein, RseA Pnap_3067 11 COG3073 RseA, Negative regulator of sigma E activity Signal transduction mechanisms 121603064 Common - branched-chain amino acid aminotransferase Pnap_0147 216 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 121603224 Common - phospholipid/glycerol acyltransferase Pnap_0309 133 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 121603117 Common - translation elongation factor G Pnap_0200 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 121604429 Common - putative monovalent cation/H+ antiporter subunit C Pnap_1523 93 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 121606719 Common - binding-protein-dependent transport systems inner membrane component Pnap_3831 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 121604254 Common - retron reverse transcriptase Pnap_1347 2 None None None 121606317 Common - transcriptional regulator, TraR/DksA family Pnap_3428 133 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 121605286 Common - putative serine protein kinase, PrkA Pnap_2387 69 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 121605466 Common - hypothetical protein Pnap_2571 8 COG4256 HemP, Hemin uptake protein Inorganic ion transport and metabolism 121605899 Common - cytochrome c, class I Pnap_3008 58 COG2863 COG2863, Cytochrome c553 Energy production and conversion 121603158 Nonpathogen - hypothetical protein Pnap_0241 1 None None None 121606790 Common - acriflavin resistance protein Pnap_3902 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 121603640 Common - pyrroloquinoline quinone biosynthesis protein PqqE Pnap_0729 140 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 121603923 Common - putative substrate-binding periplasmic (PBP) ABC transporter protein Pnap_1014 26 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 121605792 Common - transposase Pnap_2901 38 None None None 121604008 Common - protein of unknown function DUF6, transmembrane Pnap_1099 80 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 121603026 Nonpathogen - hypothetical protein Pnap_0109 1 None None None 121605897 Common - Ankyrin Pnap_3006 112 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 121604206 Common - transporter, hydrophobe/amphiphile efflux-1 (HAE1) family Pnap_1299 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 121605181 Nonpathogen - hypothetical protein Pnap_2281 1 None None None 121606360 Common - phospholipase D/Transphosphatidylase Pnap_3471 143 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 121603092 Common - Rod shape-determining protein MreD Pnap_0175 35 COG2891 MreD, Cell shape-determining protein Cell envelope biogenesis, outer membrane 121605385 Common - Oxidoreductase FAD-binding domain protein Pnap_2489 158 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 121606369 Common - polysaccharide biosynthesis protein CapD Pnap_3480 154 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 121605055 Nonpathogen - hypothetical protein Pnap_2155 2 None None None 121606789 Common - efflux transporter, RND family, MFP subunit Pnap_3901 120 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 121605023 Common - transcriptional regulator, MarR family Pnap_2122 37 COG1846 MarR, Transcriptional regulators Transcription 121605483 Common - protein tyrosine phosphatase Pnap_2588 123 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 121606070 Nonpathogen - hypothetical protein Pnap_3180 3 None None None 121606799 Common - hypothetical protein Pnap_3911 9 None None None 121606835 Common - DNA polymerase, beta domain protein region Pnap_3948 46 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 121603549 Common - ABC transporter domain protein Pnap_0638 249 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 121603192 Common - transposase, IS4 family protein Pnap_0276 29 None None None 121604420 Common - protein of unknown function DUF461 Pnap_1514 74 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 121605871 Common - hypothetical protein Pnap_2980 4 COG4982 COG4982, 3-oxoacyl- acyl-carrier protein 121604774 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase Pnap_1872 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 121603677 Common - type IV-A pilus assembly ATPase PilB Pnap_0766 215 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 121603765 Common - protein of unknown function DUF490 Pnap_0856 101 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 121605817 Common - hypothetical protein Pnap_2926 108 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 121605106 Common - phosphate ABC transporter, periplasmic phosphate-binding protein Pnap_2206 144 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 121605210 Common - homocitrate synthase Pnap_2310 195 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 121606184 Common - phage tail X family protein Pnap_3294 12 COG5004 COG5004, P2-like prophage tail protein X General function prediction only 121603504 Common - transposase, IS4 family protein Pnap_0593 61 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 121604840 Common - Glutathione S-transferase, N-terminal domain Pnap_1938 32 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 121606333 Common - transcriptional regulator, BadM/Rrf2 family Pnap_3444 162 COG1959 COG1959, Predicted transcriptional regulator Transcription 121606893 Common - transposase Pnap_4009 15 None None None 121603456 Common - aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein Pnap_0544 71 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 121606242 Common - response regulator receiver protein Pnap_3353 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 121602989 Common - transcriptional regulator, LysR family Pnap_0071 167 COG0583 LysR, Transcriptional regulator Transcription 121606942 Common - glutaredoxin Pnap_4059 22 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 121605395 Common - hypothetical protein Pnap_2499 19 None None None 121605739 Common - hypothetical protein Pnap_2846 8 None None None 121606560 Nonpathogen - hypothetical protein Pnap_3672 1 None None None 121605756 Common - Glutamate--ammonia ligase Pnap_2864 225 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 121606440 Common - channel protein, hemolysin III family Pnap_3552 115 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 121603407 Common - cytochrome bd ubiquinol oxidase, subunit I Pnap_0494 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 121605144 Common - hypothetical protein Pnap_2244 3 None None None 121604408 Common - TRAP dicarboxylate transporter- DctP subunit Pnap_1502 76 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 121604535 Common - protein of unknown function DUF6, transmembrane Pnap_1629 49 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 121606833 Common - Fimbrial protein pilin Pnap_3945 8 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 121606921 Common - transcriptional regulator, LysR family Pnap_4038 157 COG0583 LysR, Transcriptional regulator Transcription 121603325 Common - putative transposase of insertion sequence ISRm10-1 Pnap_0410 41 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 121603046 Common - protein of unknown function DUF6, transmembrane Pnap_0129 17 COG2962 RarD, Predicted permeases General function prediction only 121602926 Common - septum site-determining protein MinD Pnap_0008 136 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 121603557 Common - putative ubiquinone biosynthesis protein Pnap_0646 49 COG2941 CAT5, Ubiquinone biosynthesis protein COQ7 Coenzyme metabolism 121605697 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase Pnap_2803 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 121606756 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase Pnap_3868 184 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 121605046 Common - cobyric acid synthase CobQ Pnap_2146 150 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 121606321 Common - PUA domain containing protein Pnap_3432 137 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 121606458 Common - MscS Mechanosensitive ion channel Pnap_3570 56 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 121604762 Nonpathogen - hypothetical protein Pnap_1860 1 None None None 121606652 Common - two component transcriptional regulator, LuxR family Pnap_3764 208 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 121606575 Common - integral membrane sensor signal transduction histidine kinase Pnap_3687 214 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121605973 Common - peptidase S49 Pnap_3082 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 121603169 Common - ATP synthase F1, delta subunit Pnap_0252 174 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 121606494 Common - Extracellular ligand-binding receptor Pnap_3606 80 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 121604543 Common - transposase IS116/IS110/IS902 family protein Pnap_1637 80 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 121606060 Common - SirA family protein Pnap_3170 92 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 121603442 Common - transcriptional regulator, LysR family Pnap_0529 176 COG0583 LysR, Transcriptional regulator Transcription 121605880 Common - pyridoxamine 5'-phosphate oxidase Pnap_2989 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 121605760 Common - protein of unknown function DUF6, transmembrane Pnap_2869 107 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 121604758 Common kgd alpha-ketoglutarate decarboxylase Pnap_1856 147 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 121604075 Common - DedA protein (DSG-1 protein) Pnap_1167 151 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 121604003 Common - glutamyl-tRNA synthetase Pnap_1094 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 121604597 Common - hypothetical protein Pnap_1692 3 COG1406 COG1406, Predicted inhibitor of MCP methylation, homolog of CheC Cell motility and secretion 121604348 Common - ABC transporter related Pnap_1442 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 121602951 Nonpathogen - hypothetical protein Pnap_0033 1 None None None 121606633 Common - response regulator receiver protein Pnap_3745 178 COG4566 TtrR, Response regulator Signal transduction mechanisms 121603882 Common - UreE urease accessory domain protein Pnap_0973 61 COG2371 UreE, Urease accessory protein UreE Posttranslational modification, protein turnover, chaperones 121606815 Nonpathogen - hypothetical protein Pnap_3927 2 None None None 121604790 Common - lipolytic enzyme, G-D-S-L family Pnap_1888 95 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 121603798 Common - RNA polymerase, sigma 32 subunit, RpoH Pnap_0889 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 121604864 Common - hydrogenase accessory protein HypB Pnap_1963 107 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 121603868 Common - putative lipoprotein Pnap_0959 11 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 121603550 Common - 5-nucleotidase Pnap_0639 30 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 121605599 Common - regulatory proteins, IclR Pnap_2705 113 COG1414 IclR, Transcriptional regulator Transcription 121604779 Common - RNA chaperone Hfq Pnap_1877 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 121602945 Nonpathogen - hypothetical protein Pnap_0027 2 None None None 121606431 Common - ATP-dependent RNA helicase DbpA Pnap_3542 229 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 121605982 Common - phosphoenolpyruvate carboxylase Pnap_3091 116 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 121604489 Common - NifT/FixU family protein Pnap_1583 21 COG5554 NifU, Nitrogen fixation protein Secondary metabolites biosynthesis, transport, and catabolism 121604097 Common - putative fkbp-type peptidyl-prolyl cis-trans isomerase (rotamase) protein Pnap_1190 105 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 121605803 Nonpathogen - Tfp pilus assembly protein PilX-like protein Pnap_2912 3 COG4726 PilX, Tfp pilus assembly protein PilX Cell motility and secretion / Intracellular trafficking and secretion 121606509 Common - AMP-dependent synthetase and ligase Pnap_3621 222 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 121606665 Common - hypothetical protein Pnap_3777 6 COG3198 COG3198, Uncharacterized protein conserved in bacteria Function unknown 121603635 Common - hypothetical protein Pnap_0724 20 COG5501 COG5501, Predicted secreted protein Function unknown 121605257 Common - putative signal peptide protein Pnap_2358 31 COG5572 COG5572, Predicted integral membrane protein Function unknown 121603804 Common - pantetheine-phosphate adenylyltransferase Pnap_0895 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 121605921 Common - malate dehydrogenase Pnap_3030 110 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 121606198 Common - phage tail sheath protein Pnap_3308 40 COG3497 COG3497, Phage tail sheath protein FI General function prediction only 121606700 Common - porin, Gram-negative type Pnap_3812 22 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 121603290 Common - CoA-binding domain protein Pnap_0375 124 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 121604356 Common - protein of unknown function DUF1365 Pnap_1450 61 COG3496 COG3496, Uncharacterized conserved protein Function unknown 121606883 Common - hypothetical protein Pnap_3997 3 None None None 121604312 Nonpathogen - hypothetical protein Pnap_1406 13 COG3850 NarQ, Signal transduction histidine kinase, nitrate/nitrite-specific Signal transduction mechanisms 121606519 Common - putative proline rich signal peptide protein Pnap_3631 21 None None None 121605134 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Pnap_2234 222 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 121603975 Nonpathogen - hypothetical protein Pnap_1066 5 None None None 121605429 Nonpathogen - hypothetical protein Pnap_2534 1 None None None 121606065 Common - UTP-glucose-1-phosphate uridylyltransferase GalU Pnap_3175 229 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 121605838 Common - aldehyde dehydrogenase Pnap_2947 216 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 121605673 Common - conserved hypothetical signal peptide protein Pnap_2779 12 None None None 121604884 Common - Phosphoribulokinase Pnap_1983 51 COG3954 PrkB, Phosphoribulokinase Energy production and conversion 121606979 Common - 2OG-Fe(II) oxygenase Pnap_4097 56 COG3145 AlkB, Alkylated DNA repair protein DNA replication, recombination, and repair 121603723 Common - hypothetical protein Pnap_0812 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 121605494 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pnap_2600 70 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 121606526 Common - LemA family protein Pnap_3638 131 COG1704 LemA, Uncharacterized conserved protein Function unknown 121605060 Common cbiD cobalt-precorrin-6A synthase Pnap_2160 76 COG1903 CbiD, Cobalamin biosynthesis protein CbiD Coenzyme metabolism 121604401 Nonpathogen - hypothetical protein Pnap_1495 1 None None None 121605745 Common - ribosomal protein L35 Pnap_2852 177 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 121606546 Common - cytochrome B561 Pnap_3658 51 COG3658 COG3658, Cytochrome b Energy production and conversion 121603740 Common - hypothetical protein Pnap_0831 14 None None None 121604213 Nonpathogen - hypothetical protein Pnap_1306 9 None None None 121605821 Common - DoxX family protein Pnap_2930 40 COG2259 COG2259, Predicted membrane protein Function unknown 121603276 Nonpathogen - hypothetical protein Pnap_0361 1 None None None 121605084 Nonpathogen - hypothetical protein Pnap_2184 1 None None None 121606422 Common - ABC transporter related Pnap_3533 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 121604414 Common - transcriptional regulator of molybdate metabolism, LysR family Pnap_1508 62 COG1910 COG1910, Periplasmic molybdate-binding protein/domain Inorganic ion transport and metabolism 121603773 Common - beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family Pnap_0864 119 COG1414 IclR, Transcriptional regulator Transcription 121606097 Common - inner-membrane translocator Pnap_3207 152 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 121605741 Common - integration host factor, alpha subunit Pnap_2848 205 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 121605590 Common - Antibiotic biosynthesis monooxygenase Pnap_2696 23 COG3224 COG3224, Uncharacterized protein conserved in bacteria Function unknown 121603513 Common - transcriptional regulator, GntR family Pnap_0602 129 COG1802 GntR, Transcriptional regulators Transcription 121606298 Common - crossover junction endodeoxyribonuclease RuvC Pnap_3409 193 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 121606375 Nonpathogen - hypothetical protein Pnap_3486 2 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 121605524 Common - 4-aminobutyrate aminotransferase Pnap_2630 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 121606011 Common - hypothetical protein Pnap_3121 3 None None None 121606683 Common - magnesium and cobalt transport protein CorA Pnap_3795 145 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 121605968 Common - fatty acid/phospholipid synthesis protein PlsX Pnap_3077 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 121606655 Nonpathogen - hypothetical protein Pnap_3767 1 COG3722 MtlR, Transcriptional regulator Transcription 121603179 Common - hypothetical protein Pnap_0262 15 None None None 121603711 Common - Extracellular ligand-binding receptor Pnap_0800 120 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 121605605 Common - NIPSNAP family containing protein Pnap_2711 18 None None None 121606411 Common - integral membrane sensor signal transduction histidine kinase Pnap_3522 163 COG4564 COG4564, Signal transduction histidine kinase Signal transduction mechanisms 121603249 Common - ribosomal protein S8 Pnap_0334 243 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 121605206 Common - UspA domain protein Pnap_2306 159 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 121606563 Common - Methyltransferase type 11 Pnap_3675 185 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 121603114 Common - Serine-type D-Ala-D-Ala carboxypeptidase Pnap_0197 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 121605602 Common - transcriptional regulator, AraC family Pnap_2708 96 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 121606623 Common - hypothetical protein Pnap_3735 6 COG2342 COG2342, Predicted extracellular endo alpha-1,4 polygalactosaminidase or related polysaccharide hydrolase Carbohydrate transport and metabolism 121603583 Common - type IV pilus assembly protein PilM Pnap_0672 80 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 121605502 Common - periplasmic binding protein/LacI transcriptional regulator Pnap_2608 86 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 121603969 Common - transglutaminase domain protein Pnap_1060 88 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 121604511 Common - DNA primase Pnap_1605 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 121603030 Common - hypothetical protein Pnap_0113 4 None None None 121604373 Common - ribosome small subunit-dependent GTPase A Pnap_1467 163 COG1162 COG1162, Predicted GTPases General function prediction only 121603825 Common - transport-associated Pnap_0916 45 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 121605924 Common - succinate dehydrogenase, cytochrome b subunit Pnap_3033 52 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 121603996 Common - arsenate reductase and related Pnap_1087 93 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 121606525 Common - peptidase M48, Ste24p Pnap_3637 182 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 121604467 Common - Shikimate dehydrogenase Pnap_1561 121 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 121605534 Common - two component transcriptional regulator, LuxR family Pnap_2640 170 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 121604583 Common - Hydroxyacylglutathione hydrolase Pnap_1678 204 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 121605539 Common - protein of unknown function UPF0150 Pnap_2645 40 COG1598 COG1598, Uncharacterized conserved protein Function unknown 121604395 Common - extracellular solute-binding protein, family 3 Pnap_1489 177 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 121604197 Common - short chain dehydrogenase Pnap_1290 178 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 121603107 Common - protein of unknown function DUF72 Pnap_0190 96 COG1801 COG1801, Uncharacterized conserved protein Function unknown 121604844 Common - RNA binding S1 domain protein Pnap_1942 209 COG2183 Tex, Transcriptional accessory protein Transcription 121606772 Common secF preprotein translocase subunit SecF Pnap_3884 203 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 121605410 Common - hypothetical protein Pnap_2514 18 None None None 121603099 Common - protein of unknown function DUF140 Pnap_0182 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 121605111 Common - putative phosphohistidine phosphatase, SixA Pnap_2211 53 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 121603565 Common - transaldolase B Pnap_0654 182 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 121606115 Common - acyl-CoA dehydrogenase domain protein Pnap_3225 134 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 121604683 Common aceE pyruvate dehydrogenase subunit E1 Pnap_1781 150 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 121605662 Common - hypothetical protein Pnap_2768 14 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 121606785 Common - hypothetical protein Pnap_3897 57 COG3164 COG3164, Predicted membrane protein Function unknown 121603259 Common rpsD 30S ribosomal protein S4 Pnap_0344 223 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 121604453 Common - Disulphide bond formation protein DsbB Pnap_1547 53 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 121604337 Common - respiratory-chain NADH dehydrogenase, subunit 1 Pnap_1431 190 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 121606972 Common - Heavy metal transport/detoxification protein Pnap_4089 32 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 121603736 Common - NADH dehydrogenase (quinone) Pnap_0825 160 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 121605275 Common - electron transport complex, RnfABCDGE type, B subunit Pnap_2376 114 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 121604741 Common - inner-membrane translocator Pnap_1839 72 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 121603651 Common - protein of unknown function DUF815 Pnap_0740 89 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 121604524 Common - ABC transporter related Pnap_1618 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 121603596 Common - ABC transporter related Pnap_0685 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 121604189 Common - cytochrome c, class I Pnap_1282 72 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 121603664 Common - CDP-diacylglycerol--serine O-phosphatidyltransferase Pnap_0753 151 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 121603872 Common - hypothetical protein Pnap_0963 24 None None None 121604499 Common - TRAP dicarboxylate transporter, DctP subunit Pnap_1593 121 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 121603089 Common - glutamyl-tRNA(Gln) amidotransferase, C subunit Pnap_0172 129 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 121606036 Common - fumarylacetoacetate (FAA) hydrolase Pnap_3146 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 121604362 Common - hypothetical protein Pnap_1456 30 None None None 121606380 Common - dTDP-glucose 4,6-dehydratase Pnap_3491 231 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 121605178 Common - hypothetical protein Pnap_2278 5 None None None 121605482 Common - regulatory protein, ArsR Pnap_2587 58 COG0640 ArsR, Predicted transcriptional regulators Transcription 121603417 Common anmK anhydro-N-acetylmuramic acid kinase Pnap_0504 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 121604917 Common - binding-protein-dependent transport systems inner membrane component Pnap_2016 219 COG4174 COG4174, ABC-type uncharacterized transport system, permease component General function prediction only 121603213 Common - hypothetical protein Pnap_0298 21 COG3016 PhuW, Uncharacterized iron-regulated protein Function unknown 121606119 Common - isoleucyl-tRNA synthetase Pnap_3229 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 121603471 Nonpathogen - hypothetical protein Pnap_0559 1 None None None 121603463 Common - inner-membrane translocator Pnap_0551 51 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 121604319 Common - nitrate ABC transporter, inner membrane subunit Pnap_1413 195 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 121605163 Nonpathogen - hypothetical protein Pnap_2263 1 None None None 121604566 Common - major facilitator superfamily MFS_1 Pnap_1660 203 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 121606427 Common - Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein Pnap_3538 113 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 121603831 Common - two component transcriptional regulator, LuxR family Pnap_0922 220 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 121606995 Common - 60 kDa inner membrane insertion protein Pnap_4113 211 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 121605947 Common - glycoside hydrolase, family 3 domain protein Pnap_3056 175 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 121605270 Common - protein of unknown function DUF81 Pnap_2371 83 COG0730 COG0730, Predicted permeases General function prediction only 121606481 Nonpathogen - hypothetical protein Pnap_3593 3 None None None 121605916 Common - peptidase U32 Pnap_3025 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 121606695 Common - Uncharacterized protein UPF0065 Pnap_3807 65 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121605072 Common - cobalamin (vitamin B12) biosynthesis CbiX protein Pnap_2172 69 COG2138 COG2138, Uncharacterized conserved protein Function unknown 121605107 Common - beta-Ig-H3/fasciclin Pnap_2207 68 COG2335 COG2335, Secreted and surface protein containing fasciclin-like repeats Cell envelope biogenesis, outer membrane 121603232 Common - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family-like protein Pnap_0317 4 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 121606673 Common - Rare lipoprotein B Pnap_3785 20 COG2980 RlpB, Rare lipoprotein B Cell envelope biogenesis, outer membrane 121603043 Nonpathogen - hypothetical protein Pnap_0126 1 None None None 121606752 Common - Thioredoxin domain Pnap_3864 142 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 121604859 Nonpathogen - hypothetical protein Pnap_1958 2 None None None 121606403 Common - response regulator receiver protein Pnap_3514 6 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 121603942 Common - cytochrome c, class I Pnap_1033 26 COG4654 COG4654, Cytochrome c551/c552 Energy production and conversion 121603526 Common - Helix-turn-helix, type 11 domain protein Pnap_0615 49 COG1414 IclR, Transcriptional regulator Transcription 121604518 Common - phasin family protein Pnap_1612 16 None None None 121604555 Common - Shikimate dehydrogenase Pnap_1649 155 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 121604850 Common - DNA-directed DNA polymerase Pnap_1949 211 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 121605841 Common - Extracellular ligand-binding receptor Pnap_2950 127 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 121603234 Common - glycosyl transferase, family 9 Pnap_0319 75 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 121606736 Common - transglutaminase domain protein Pnap_3848 78 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 121604016 Common - glycogen/starch synthases, ADP-glucose type Pnap_1107 121 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 121605331 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Pnap_2432 161 COG1146 COG1146, Ferredoxin Energy production and conversion 121605221 Common - protein of unknown function DUF683 Pnap_2321 15 COG5420 COG5420, Uncharacterized conserved small protein containing a coiled-coil domain Function unknown 121604309 Common - hypothetical protein Pnap_1403 130 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 121606203 Common - phage tail tape measure protein, TP901 family Pnap_3313 30 COG5283 COG5283, Phage-related tail protein Function unknown 121605317 Common - alkanesulfonate monooxygenase Pnap_2418 87 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 121606885 Common - heavy metal translocating P-type ATPase Pnap_4001 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 121604375 Common - Ste24 endopeptidase Pnap_1469 64 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 121605474 Common - stationary-phase survival protein SurE Pnap_2579 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 121604371 Common - NUDIX hydrolase Pnap_1465 125 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 121606764 Common - AzlC family protein Pnap_3876 79 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 121604266 Common - DNA mismatch repair protein MutS Pnap_1359 198 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 121603487 Common - protein of unknown function DUF1549 Pnap_0575 5 None None None 121604681 Common - response regulator receiver protein Pnap_1779 212 COG4566 TtrR, Response regulator Signal transduction mechanisms 121603145 Common - extracellular solute-binding protein, family 1 Pnap_0228 42 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 121603992 Common - protein of unknown function DUF1255 Pnap_1083 50 COG3123 COG3123, Uncharacterized protein conserved in bacteria Function unknown 121603301 Common - helix-turn-helix domain protein Pnap_0386 40 COG2944 COG2944, Predicted transcriptional regulator Transcription 121605623 Common - inner-membrane translocator Pnap_2729 149 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 121603250 Common - ribosomal protein L6 Pnap_0335 229 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 121603563 Common - transcriptional regulator, RpiR family Pnap_0652 97 COG1737 RpiR, Transcriptional regulators Transcription 121604665 Common - phosphatidate cytidylyltransferase Pnap_1763 213 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 121603429 Common - PP-loop domain protein Pnap_0516 165 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 121603925 Common - tartrate dehydrogenase Pnap_1016 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 121604575 Common - DNA polymerase III, subunits gamma and tau Pnap_1670 248 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 121604839 Common - putative transcriptional regulator, AsnC family Pnap_1937 144 COG1522 Lrp, Transcriptional regulators Transcription 121606823 Nonpathogen - hypothetical protein Pnap_3935 1 None None None 121604120 Common - PilT protein domain protein Pnap_1213 55 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 121603424 Common - protein of unknown function DUF511 Pnap_0511 17 COG2958 COG2958, Uncharacterized protein conserved in bacteria Function unknown 121603287 Common - Methyltransferase type 12 Pnap_0372 27 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 121605510 Common - ribose-5-phosphate isomerase A Pnap_2616 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 121604576 Common - conserved hypothetical protein 103 Pnap_1671 168 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 121606033 Common - transcriptional regulator, MarR family Pnap_3143 137 COG1846 MarR, Transcriptional regulators Transcription 121606276 Nonpathogen - histone protein Pnap_3387 1 None None None 121603704 Common - NAD(P)H dehydrogenase (quinone) Pnap_0793 59 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 121604127 Common - histone deacetylase superfamily Pnap_1220 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 121605630 Common - Ferredoxin--NADP(+) reductase Pnap_2736 106 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 121605459 Common - Uncharacterised conserved protein UCP028101 Pnap_2564 24 COG3490 COG3490, Uncharacterized protein conserved in bacteria Function unknown 121604891 Common - hypothetical protein Pnap_1990 27 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 121603932 Common - benzoylformate decarboxylase Pnap_1023 217 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 121604222 Common - putative transcriptional regulator, Crp/Fnr family Pnap_1315 28 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 121603365 Common - response regulator receiver protein Pnap_0451 88 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 121604949 Common - Tetratricopeptide TPR_2 repeat protein Pnap_2048 77 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 121605004 Common - Radical SAM domain protein Pnap_2103 32 COG2516 COG2516, Biotin synthase-related enzyme General function prediction only 121605453 Common - TonB-dependent siderophore receptor Pnap_2558 108 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 121604914 Common - protein of unknown function DUF150 Pnap_2013 126 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 121605126 Common - molybdopterin biosynthesis MoaE Pnap_2226 159 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 121603015 Common - UspA domain protein Pnap_0098 108 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 121604782 Common - HflC protein Pnap_1880 140 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 121606685 Common - AMP-dependent synthetase and ligase Pnap_3797 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 121604920 Common - DNA ligase Pnap_2019 33 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 121603153 Common - major facilitator superfamily MFS_1 Pnap_0236 88 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 121605867 Common - MaoC domain protein dehydratase Pnap_2976 59 COG2030 MaoC, Acyl dehydratase Lipid metabolism 121605683 Common - OmpA/MotB domain protein Pnap_2789 168 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 121606610 Common - SEC-C motif domain protein Pnap_3722 6 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 121606863 Common - hypothetical protein Pnap_3976 2 None None None 121605315 Common - ABC transporter related Pnap_2416 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 121606393 Common - transcriptional regulator, LysR family Pnap_3504 183 COG0583 LysR, Transcriptional regulator Transcription 121603538 Common - hypothetical protein Pnap_0627 6 None None None 121604610 Common - hypothetical protein Pnap_1705 16 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 121604435 Common - Extensin family protein Pnap_1529 37 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 121606208 Common - phage transcriptional activator, Ogr/delta Pnap_3319 2 None None None 121604027 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pnap_1119 46 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 121606394 Common - Formyl-CoA transferase Pnap_3505 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 121605338 Common - MiaB-like tRNA modifying enzyme YliG Pnap_2439 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 121605930 Common - isopropylmalate isomerase large subunit Pnap_3039 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 121604034 Common - type I secretion outer membrane protein, TolC family Pnap_1126 132 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 121605303 Common - Glutathione S-transferase, N-terminal domain Pnap_2404 94 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 121606076 Nonpathogen - hypothetical protein Pnap_3186 3 None None None 121602921 Nonpathogen - hypothetical protein Pnap_0003 1 None None None 121606095 Common - ABC transporter related Pnap_3205 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 121604586 Common - efflux transporter, RND family, MFP subunit Pnap_1681 156 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 121604384 Common - DNA polymerase I Pnap_1478 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 121604609 Nonpathogen - hypothetical protein Pnap_1704 1 None None None 121604702 Common - isochorismatase hydrolase Pnap_1800 82 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 121605907 Common - hypothetical protein Pnap_3016 41 COG3564 COG3564, Uncharacterized protein conserved in bacteria Function unknown 121603970 Common - transglutaminase, N-terminal domain protein Pnap_1061 103 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 121606936 Common - inner-membrane translocator Pnap_4053 104 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 121606477 Nonpathogen - hypothetical protein Pnap_3589 1 None None None 121603949 Common - adenosine deaminase Pnap_1040 101 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 121604602 Common - hypothetical protein Pnap_1697 68 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 121604739 Common - acyl-CoA synthetase Pnap_1837 221 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 121606344 Common - ABC transporter related Pnap_3455 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 121603729 Common metG methionyl-tRNA synthetase Pnap_0818 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 121603412 Common - RNA-3'-phosphate cyclase Pnap_0499 47 COG0430 RCL1, RNA 3'-terminal phosphate cyclase RNA processing and modification 121606581 Common - ABC transporter related Pnap_3693 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 121606013 Common - imidazole glycerol phosphate synthase subunit HisF Pnap_3123 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 121603332 Common - ISXo7 transposase Pnap_0418 39 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 121603360 Common - histidinol-phosphate phosphatase family protein Pnap_0446 127 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 121606466 Common - YceI family protein Pnap_3578 115 COG2353 COG2353, Uncharacterized conserved protein Function unknown 121604168 Common - multicopper oxidase, type 3 Pnap_1261 131 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 121605765 Common - prolipoprotein diacylglyceryl transferase Pnap_2874 206 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 121606334 Common - cysteine synthase A Pnap_3445 222 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 121606917 Common - putative transposase of insertion sequence ISRm10-1 Pnap_4034 41 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 121605675 Common - molybdopterin binding domain Pnap_2781 127 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 121604564 Common - oxidoreductase domain protein Pnap_1658 169 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 121606855 Common - peptidylprolyl isomerase, FKBP-type Pnap_3968 130 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 121603308 Common - hypothetical protein Pnap_0393 5 None None None 121603624 Common - ubiquinol-cytochrome c reductase, iron-sulfur subunit Pnap_0713 90 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 121603339 Common - transposase, IS4 family protein Pnap_0425 27 None None None 121603858 Common - malonate decarboxylase subunit beta Pnap_0949 126 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 121604885 Common - transketolase Pnap_1984 221 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 121605001 Common - glycosyl transferase, group 1 Pnap_2100 185 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 121604827 Common - MotA/TolQ/ExbB proton channel Pnap_1925 108 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 121606239 Common - CheA signal transduction histidine kinases Pnap_3350 224 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 121603101 Common - Mammalian cell entry related domain protein Pnap_0184 66 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 121604080 Common - putative iron-sulfur cluster binding protein Pnap_1172 132 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 121605888 Common - transposase Pnap_2997 38 None None None 121606770 Common - protein of unknown function DUF494 Pnap_3882 40 COG2922 Smg, Uncharacterized protein conserved in bacteria Function unknown 121604753 Common - two component transcriptional regulator, LuxR family Pnap_1851 197 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 121603356 Common - L-asparaginases, type II Pnap_0442 120 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 121603189 Common - phosphoheptose isomerase Pnap_0272 124 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 121606488 Common - two component transcriptional regulator, winged helix family Pnap_3600 210 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 121603691 Common - protein of unknown function DUF971 Pnap_0780 48 COG3536 COG3536, Uncharacterized protein conserved in bacteria Function unknown 121604765 Common - helicase c2 Pnap_1863 143 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 121603811 Common - Tetratricopeptide domain protein Pnap_0902 114 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 121603202 Common - hypothetical protein Pnap_0287 3 None None None 121606533 Common - NusG antitermination factor Pnap_3645 215 COG0250 NusG, Transcription antiterminator Transcription 121604328 Common - Triose-phosphate isomerase Pnap_1422 216 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 121604544 Common - hypothetical protein Pnap_1638 14 None None None 121604942 Common - molybdate ABC transporter, ATPase subunit Pnap_2041 249 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 121605663 Common - putative ribonuclease BN Pnap_2769 90 COG1295 Rbn, Predicted membrane protein Function unknown 121604791 Common - ABC transporter related Pnap_1889 249 COG4181 COG4181, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 121605036 Common - 3-hydroxyacyl-CoA dehydrogenase, NAD-binding Pnap_2135 161 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 121604770 Common - Nucleoside-diphosphate kinase Pnap_1868 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 121604711 Common - N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase Pnap_1809 212 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 121603843 Common - 3-methyl-2-oxobutanoate hydroxymethyltransferase Pnap_0934 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 121604507 Common - Uncharacterized protein UPF0065 Pnap_1601 75 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121603134 Common - Redoxin domain protein Pnap_0217 124 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 121604537 Common - alpha/beta hydrolase fold Pnap_1631 65 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 121605452 Common - bacterioferritin Pnap_2557 104 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 121604956 Nonpathogen - hypothetical protein Pnap_2055 2 None None None 121604303 Nonpathogen - hypothetical protein Pnap_1397 1 None None None 121604646 Common - putative transposase Pnap_1744 35 COG5659 COG5659, FOG: Transposase DNA replication, recombination, and repair 121606817 Nonpathogen - hypothetical protein Pnap_3929 1 None None None 121604160 Common - hypothetical protein Pnap_1253 2 None None None 121606042 Common - type II secretion system protein E Pnap_3152 218 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 121605250 Common - nitrogenase-associated protein Pnap_2351 18 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 121603813 Common - hypothetical protein Pnap_0904 34 COG1160 COG1160, Predicted GTPases General function prediction only 121606726 Common - FAD linked oxidase domain protein Pnap_3838 151 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 121606152 Common - filamentation induced by cAMP protein Fic Pnap_3262 25 COG3177 COG3177, Uncharacterized conserved protein Function unknown 121606007 Common - polysaccharide biosynthesis protein CapD Pnap_3117 136 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 121606910 Nonpathogen - hypothetical protein Pnap_4026 2 COG2361 COG2361, Uncharacterized conserved protein Function unknown 121604987 Nonpathogen - hypothetical protein Pnap_2086 4 None None None 121605034 Common - acetoacetyl-CoA synthase Pnap_2133 203 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 121605296 Common - hypothetical protein Pnap_2397 29 COG4327 COG4327, Predicted membrane protein Function unknown 121603402 Common - S-adenosyl-L-homocysteine hydrolase Pnap_0489 177 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 121603888 Common - response regulator receiver protein Pnap_0979 224 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 121604238 Nonpathogen - hypothetical protein Pnap_1331 5 None None None 121606552 Common - uncharacterized enzyme Pnap_3664 61 COG2170 COG2170, Uncharacterized conserved protein Function unknown 121606642 Common - nitroreductase Pnap_3754 82 COG0778 NfnB, Nitroreductase Energy production and conversion 121603542 Common - hypothetical protein Pnap_0631 7 None None None 121606214 Nonpathogen - hypothetical protein Pnap_3325 1 None None None 121605726 Common - Rhodanese domain protein Pnap_2832 128 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 121605782 Common - acetyl-CoA carboxylase, carboxyl transferase, alpha subunit Pnap_2891 186 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 121604592 Common - molybdenum cofactor synthesis domain Pnap_1687 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 121606359 Common - phasin family protein Pnap_3470 16 None None None 121605448 Nonpathogen - hypothetical protein Pnap_2553 1 None None None 121603613 Common - Phosphoribosyl-AMP cyclohydrolase Pnap_0702 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 121606309 Common - phospho-N-acetylmuramoyl-pentapeptide-transferase Pnap_3420 216 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 121606402 Common - integral membrane sensor signal transduction histidine kinase Pnap_3513 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121603618 Common tatB sec-independent translocase Pnap_0707 22 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 121603128 Common - ribosomal protein L29 Pnap_0211 8 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 121604675 Common - tRNA/rRNA methyltransferase (SpoU) Pnap_1773 145 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 121605320 Common - NADPH-dependent FMN reductase Pnap_2421 54 COG0431 COG0431, Predicted flavoprotein General function prediction only 121605603 Common - short-chain dehydrogenase/reductase SDR Pnap_2709 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 121603897 Nonpathogen - hypothetical protein Pnap_0988 1 None None None 121605576 Common - hypothetical protein Pnap_2682 3 None None None 121604997 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Pnap_2096 82 COG0348 NapH, Polyferredoxin Energy production and conversion 121604227 Nonpathogen - hypothetical protein Pnap_1320 1 None None None 121606056 Common - hypothetical protein Pnap_3166 80 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 121605262 Common - transport system permease protein Pnap_2363 184 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 121606559 Common - putative transcriptional regulator, Crp/Fnr family Pnap_3671 30 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 121603824 Common - transport-associated Pnap_0915 35 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 121605233 Common - F0F1-ATPase subunit, putative Pnap_2334 18 None None None 121603383 Common - helix-turn-helix- domain containing protein, AraC type Pnap_0469 49 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 121603862 Common - malonate/sodium symporter MadM subunit Pnap_0953 11 None None None 121604134 Common - hypothetical protein Pnap_1227 6 None None None 121603447 Common - putative transcriptional regulator, AsnC family Pnap_0535 120 COG1522 Lrp, Transcriptional regulators Transcription 121605491 Nonpathogen - hypothetical protein Pnap_2596 11 None None None 121603385 Common - Propionyl-CoA carboxylase Pnap_0471 143 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 121604908 Nonpathogen - protein of unknown function DUF6, transmembrane Pnap_2007 17 COG2962 RarD, Predicted permeases General function prediction only 121603024 Common - ABC transporter related Pnap_0107 182 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 121606249 Common - putative TIM-barrel protein, nifR3 family Pnap_3360 209 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 121604693 Common - hypothetical protein Pnap_1791 9 None None None 121605611 Common - Extracellular ligand-binding receptor Pnap_2717 136 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 121605649 Common - glutathione S-transferase-like protein Pnap_2755 64 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 121606934 Common - ABC transporter related Pnap_4051 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 121602993 Nonpathogen - hypothetical protein Pnap_0075 1 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 121603953 Common - basic membrane lipoprotein Pnap_1044 92 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 121606928 Common - domain of unknown function DUF1745 Pnap_4045 41 COG3287 COG3287, Uncharacterized conserved protein Function unknown 121605789 Common - protein of unknown function DUF980 Pnap_2898 57 COG3228 COG3228, Uncharacterized protein conserved in bacteria Function unknown 121604141 Common - Uncharacterized protein UPF0065 Pnap_1234 74 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121606619 Common - arsenite-activated ATPase ArsA Pnap_3731 77 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 121604010 Common - Ada, metal-binding domain protein Pnap_1101 135 COG2169 Ada, Adenosine deaminase Nucleotide transport and metabolism 121606969 Common - pentapeptide repeat protein Pnap_4086 69 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 121606132 Common - hypothetical protein Pnap_3242 40 COG3663 Mug, G:T/U mismatch-specific DNA glycosylase DNA replication, recombination, and repair 121604182 Common - short-chain dehydrogenase/reductase SDR Pnap_1275 201 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 121603017 Common - transcriptional regulator, LysR family Pnap_0100 134 COG0583 LysR, Transcriptional regulator Transcription 121606253 Common - sulphate transporter Pnap_3364 155 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 121603265 Common - phospholipase A1 Pnap_0350 51 COG2829 PldA, Outer membrane phospholipase A Cell envelope biogenesis, outer membrane 121606145 Common - lipoprotein releasing system, ATP-binding protein Pnap_3255 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 121603964 Nonpathogen - outer membrane protein Pnap_1055 4 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 121603376 Nonpathogen - hypothetical protein Pnap_0462 1 None None None 121605529 Common - putative agmatinase Pnap_2635 144 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 121605425 Common - TRAG family protein Pnap_2530 76 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 121603054 Common - 5-carboxymethyl-2-hydroxymuconate isomerase Pnap_0137 26 COG3232 HpaF, 5-carboxymethyl-2-hydroxymuconate isomerase Amino acid transport and metabolism 121603630 Common - ABC transporter related Pnap_0719 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 121605365 Common - Integrase, catalytic region Pnap_2468 82 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 121605589 Common - aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding Pnap_2695 122 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 121604450 Common - sulfate ABC transporter, inner membrane subunit CysT Pnap_1544 212 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 121606082 Common - mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase Pnap_3192 164 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 121605430 Common - hypothetical protein Pnap_2535 4 None None None 121606362 Common - enoyl-CoA hydratase Pnap_3473 180 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 121603575 Common - cytochrome c, class I Pnap_0664 65 COG2863 COG2863, Cytochrome c553 Energy production and conversion 121603312 Common - integral membrane sensor hybrid histidine kinase Pnap_0397 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121605243 Common - nitrogenase molybdenum-iron protein alpha chain Pnap_2344 52 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 121604961 Common - hypothetical protein Pnap_2060 2 None None None 121605702 Nonpathogen - hypothetical protein Pnap_2808 2 None None None 121605985 Common - hypothetical protein Pnap_3094 5 None None None 121603784 Common - hypothetical protein Pnap_0875 126 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 121603655 Common - Lytic transglycosylase, catalytic Pnap_0744 68 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 121604461 Common - shikimate 5-dehydrogenase Pnap_1555 203 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 121604657 Common - Peptidoglycan-binding LysM Pnap_1755 53 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 121605329 Common - Sulfate adenylyltransferase Pnap_2430 125 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 121603480 Common - acriflavin resistance protein Pnap_0568 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 121603681 Common - hypothetical protein Pnap_0770 44 COG4582 COG4582, Uncharacterized protein conserved in bacteria Function unknown 121606956 Nonpathogen - hypothetical protein Pnap_4073 1 None None None 121604814 Common - aminoglycoside phosphotransferase Pnap_1912 60 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 121603771 Common - hypothetical protein Pnap_0862 23 None None None 121604062 Common - ABC transporter related Pnap_1154 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 121602953 Common - amidase Pnap_0035 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 121605583 Common - two component transcriptional regulator, LuxR family Pnap_2689 189 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 121603435 Common - hypothetical protein Pnap_0522 16 None None None 121606635 Common - TRAP dicarboxylate transporter, DctP subunit Pnap_3747 98 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 121606350 Common - regulatory protein, MerR Pnap_3461 7 COG2452 COG2452, Predicted site-specific integrase-resolvase DNA replication, recombination, and repair 121604142 Common - hypothetical protein Pnap_1235 9 None None None 121606167 Common - peptidase M50 Pnap_3277 86 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 121605194 Nonpathogen - hypothetical protein Pnap_2294 1 None None None 121604101 Common - beta-lactamase domain protein Pnap_1194 57 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 121604114 Common - protein of unknown function DUF403 Pnap_1207 82 COG2307 COG2307, Uncharacterized protein conserved in bacteria Function unknown 121603796 Common - protoheme IX farnesyltransferase Pnap_0887 174 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 121604989 Common - UspA domain protein Pnap_2088 34 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 121606150 Nonpathogen - hypothetical protein Pnap_3260 1 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 121605323 Common - protein of unknown function DUF752 Pnap_2424 85 COG4121 COG4121, Uncharacterized conserved protein Function unknown 121606232 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferases Pnap_3343 149 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 121603606 Common hisG ATP phosphoribosyltransferase catalytic subunit Pnap_0695 211 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 121605381 Common - ring hydroxylating dioxygenase, alpha subunit Pnap_2485 80 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 121604612 Nonpathogen - hypothetical protein Pnap_1707 1 None None None 121605437 Common - transmembrane pair domain protein Pnap_2542 41 COG4125 COG4125, Predicted membrane protein Function unknown 121602929 Common - protein of unknown function DUF296 Pnap_0011 18 COG1661 COG1661, Predicted DNA-binding protein with PD1-like DNA-binding motif General function prediction only 121603038 Common - ammonium transporter Pnap_0121 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 121604796 Common - Ku domain protein Pnap_1894 63 COG1273 COG1273, Uncharacterized conserved protein Function unknown 121606873 Common - putative D--3-hydroxybutyrate oligomer hydrolase lipoprotein transmembrane Pnap_3987 9 None None None 121604148 Common - short-chain dehydrogenase/reductase SDR Pnap_1241 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 121604647 Common - transposase Pnap_1745 14 None None None 121605637 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Pnap_2743 165 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 121604996 Common - putative cytochrome c Pnap_2095 60 COG2863 COG2863, Cytochrome c553 Energy production and conversion 121606261 Common - hypothetical protein Pnap_3372 9 None None None 121603750 Common - short-chain dehydrogenase/reductase SDR Pnap_0841 233 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 121606125 Common - short-chain dehydrogenase/reductase SDR Pnap_3235 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 121604278 Common - 3-oxoacyl-(acyl carrier protein) synthase I Pnap_1371 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 121605719 Common - cytochrome c, class I Pnap_2825 39 COG3258 COG3258, Cytochrome c Energy production and conversion 121605773 Common fumC fumarate hydratase Pnap_2882 212 COG0114 FumC, Fumarase Energy production and conversion 121606139 Common - Patatin Pnap_3249 80 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 121606522 Common - transposase Pnap_3634 14 None None None 121603051 Common - protein of unknown function DUF86 Pnap_0134 22 COG2445 COG2445, Uncharacterized conserved protein Function unknown 121604624 Common - ketol-acid reductoisomerase Pnap_1719 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 121603759 Common - ABC transporter related Pnap_0850 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 121603347 Nonpathogen - hypothetical protein Pnap_0433 4 None None None 121605376 Common - OmpW family protein Pnap_2480 68 COG3047 OmpW, Outer membrane protein W Cell envelope biogenesis, outer membrane 121604466 Common - 4-hydroxyphenylpyruvate dioxygenase Pnap_1560 85 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 121603569 Common - chaperonin Cpn10 Pnap_0658 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 121606134 Common - peptidase S1 and S6, chymotrypsin/Hap Pnap_3244 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 121604894 Common - Catalase Pnap_1993 127 COG0753 KatE, Catalase Inorganic ion transport and metabolism 121606904 Common - dihydropyrimidine dehydrogenase Pnap_4020 114 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 121602924 Nonpathogen - hypothetical protein Pnap_0006 1 None None None 121603686 Common - peptide chain release factor 1 Pnap_0775 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 121605559 Common - protein of unknown function DUF1238 Pnap_2665 14 COG3802 GguC, Uncharacterized protein conserved in bacteria Function unknown 121605267 Common - TonB-dependent receptor, plug Pnap_2368 128 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 121604967 Common - hypothetical protein Pnap_2066 2 None None None 121603323 Nonpathogen - hypothetical protein Pnap_0408 1 None None None 121605770 Common - cytochrome c, class I Pnap_2879 28 COG4654 COG4654, Cytochrome c551/c552 Energy production and conversion 121606809 Common - phage integrase family protein Pnap_3921 120 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 121606286 Common - hypothetical protein Pnap_3397 7 None None None 121605300 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Pnap_2401 221 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 121605569 Nonpathogen - hypothetical protein Pnap_2675 5 None None None 121605028 Common - Uncharacterized protein UPF0065 Pnap_2127 71 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121606159 Common - twin-arginine translocation pathway signal Pnap_3269 46 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 121605674 Common - glutamine synthetase, type I Pnap_2780 226 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 121606875 Common - short-chain dehydrogenase/reductase SDR Pnap_3989 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 121604486 Common - NifZ family protein Pnap_1580 12 None None None 121603609 Common - Imidazoleglycerol-phosphate dehydratase Pnap_0698 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 121605422 Nonpathogen - hypothetical protein Pnap_2527 1 None None None 121605074 Common - putative aminotransferase Pnap_2174 236 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 121604106 Common - DNA topoisomerase IV subunit B Pnap_1199 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 121606002 Common - hypothetical protein Pnap_3111 24 COG3889 COG3889, Predicted solute binding protein General function prediction only 121604652 Common - Integrase, catalytic region Pnap_1750 139 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 121605386 Common - transcriptional regulator, LysR family Pnap_2490 115 COG0583 LysR, Transcriptional regulator Transcription 121606176 Common - protein of unknown function DUF485 Pnap_3286 53 COG3162 COG3162, Predicted membrane protein Function unknown 121606141 Common - hypothetical protein Pnap_3251 5 None None None 121606613 Common - hypothetical protein Pnap_3725 40 COG3647 COG3647, Predicted membrane protein Function unknown 121605560 Common - dihydroxy-acid dehydratase Pnap_2666 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 121603653 Common - Patatin Pnap_0742 12 None None None 121604919 Common - short-chain dehydrogenase/reductase SDR Pnap_2018 210 COG0623 FabI, Enoyl- acyl-carrier-protein 121606274 Common - ribonucleotide-diphosphate reductase subunit alpha Pnap_3385 226 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 121603733 Common - protein of unknown function DUF59 Pnap_0822 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 121604130 Common - electron transfer flavoprotein beta-subunit Pnap_1223 153 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 121603874 Nonpathogen - hypothetical protein Pnap_0965 1 None None None 121605351 Common - fumarylacetoacetate (FAA) hydrolase Pnap_2453 176 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 121605677 Common - hypothetical protein Pnap_2783 70 COG3000 ERG3, Sterol desaturase Lipid metabolism 121603892 Nonpathogen - hypothetical protein Pnap_0983 1 None None None 121605427 Nonpathogen - hypothetical protein Pnap_2532 1 None None None 121604501 Common - TRAP dicarboxylate transporter, DctM subunit Pnap_1595 135 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 121605579 Common - glycine dehydrogenase Pnap_2685 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 121603331 Common - transposase IS66 Pnap_0416 52 None None None 121605227 Common - H+-transporting two-sector ATPase, gamma subunit Pnap_2328 193 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 121603515 Common - Uncharacterized protein UPF0065 Pnap_0604 73 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121606256 Common - putative thiol:disulphide interchange protein (periplasmic) Pnap_3367 68 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 121605882 Common - poly(A) polymerase Pnap_2991 212 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 121603963 Common - hypothetical protein Pnap_1054 10 None None None 121604271 Nonpathogen - hypothetical protein Pnap_1364 2 None None None 121606123 Common - protein of unknown function DUF6, transmembrane Pnap_3233 116 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 121605089 Common - putative transcriptional regulator, MerR family Pnap_2189 45 COG0789 SoxR, Predicted transcriptional regulators Transcription 121606937 Common - ATP-binding region, ATPase domain protein domain protein Pnap_4054 187 COG3899 COG3899, Predicted ATPase General function prediction only 121604611 Common - hypothetical protein Pnap_1706 5 None None None 121604145 Common - Fibronectin, type III domain protein Pnap_1238 21 COG3509 LpqC, Poly(3-hydroxybutyrate) depolymerase Secondary metabolites biosynthesis, transport, and catabolism 121604882 Common - Ribulose-phosphate 3-epimerase Pnap_1981 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 121604802 Common - L-carnitine dehydratase/bile acid-inducible protein F Pnap_1900 113 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 121604857 Common - two component, sigma54 specific, transcriptional regulator, Fis family Pnap_1956 210 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 121606451 Common - hypothetical protein Pnap_3563 9 None None None 121603300 Nonpathogen - hypothetical protein Pnap_0385 1 None None None 121606615 Common - integral membrane sensor signal transduction histidine kinase Pnap_3727 199 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 121605614 Common - short-chain dehydrogenase/reductase SDR Pnap_2720 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 121605582 Common - integral membrane sensor hybrid histidine kinase Pnap_2688 206 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121605587 Nonpathogen - periplasmic protein, function unknown Pnap_2693 3 None None None 121603097 Common - glucose-methanol-choline oxidoreductase Pnap_0180 88 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 121605572 Common - protein of unknown function DUF6, transmembrane Pnap_2678 27 None None None 121603062 Common - P pilus assembly protein chaperone PapD-like protein Pnap_0145 21 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 121606196 Common - phage Tail Collar domain protein Pnap_3306 46 COG5301 COG5301, Phage-related tail fibre protein General function prediction only 121606792 Common - addiction module toxin, Txe/YoeB family Pnap_3904 53 COG4115 COG4115, Uncharacterized protein conserved in bacteria Function unknown 121606353 Common - MgtC/SapB transporter Pnap_3464 119 COG1285 SapB, Uncharacterized membrane protein Function unknown 121603288 Nonpathogen - hypothetical protein Pnap_0373 9 None None None 121605699 Common - poly(R)-hydroxyalkanoic acid synthase, class I Pnap_2805 73 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 121606496 Common - ABC transporter related Pnap_3608 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 121603697 Common - protein of unknown function DUF502 Pnap_0786 73 COG2928 COG2928, Uncharacterized conserved protein Function unknown 121603497 Common - cytochrome c-type biogenesis protein CcmF Pnap_0585 133 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 121603521 Common - aldehyde dehydrogenase Pnap_0610 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 121606221 Common - hypothetical protein Pnap_3332 7 None None None 121605862 Common - integral membrane sensor signal transduction histidine kinase Pnap_2971 201 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121603931 Common - aldehyde dehydrogenase Pnap_1022 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 121603122 Common - Ribosomal protein L25/L23 Pnap_0205 206 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 121605788 Common - metallophosphoesterase Pnap_2897 68 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 121603319 Nonpathogen - conserved repeat domain Pnap_0404 3 COG4719 COG4719, Uncharacterized protein conserved in bacteria Function unknown 121603036 Common - Mg chelatase, subunit ChlI Pnap_0119 188 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 121606535 Common - elongation factor Tu Pnap_3647 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 121603951 Nonpathogen - hypothetical protein Pnap_1042 1 None None None 121604102 Common - NlpBDapX family lipoprotein Pnap_1195 35 COG3317 NlpB, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 121606191 Common - GPW/gp25 family protein Pnap_3301 32 COG3628 COG3628, Phage baseplate assembly protein W General function prediction only 121606548 Common - Ribulose-phosphate 3-epimerase Pnap_3660 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 121603427 Common - Phosphoglycerate mutase Pnap_0514 151 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 121603625 Common - Cytochrome b/b6, N-terminal domain Pnap_0714 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 121605545 Nonpathogen - hypothetical protein Pnap_2651 1 None None None 121605011 Common - oxidoreductase FAD/NAD(P)-binding domain protein Pnap_2110 183 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 121605606 Common - short-chain dehydrogenase/reductase SDR Pnap_2712 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 121603393 Common - DSBA oxidoreductase Pnap_0479 44 COG3917 NahD, 2-hydroxychromene-2-carboxylate isomerase Secondary metabolites biosynthesis, transport, and catabolism 121604901 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein Pnap_2000 238 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 121602935 Common - hypothetical protein Pnap_0017 10 None None None 121603544 Common - sodium/hydrogen exchanger Pnap_0633 194 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 121605066 Common - Extracellular ligand-binding receptor Pnap_2166 145 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 121604169 Common - putative outer membrane efflux protein involved in copper resistance Pnap_1262 18 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 121605248 Common - hypothetical protein Pnap_2349 50 None None None 121603263 Common - putative transposase of insertion sequence ISRm10-1 Pnap_0348 41 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 121606723 Common - aldehyde dehydrogenase Pnap_3835 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 121605725 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Pnap_2831 107 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 121603372 Common - acetyl-CoA acetyltransferases Pnap_0458 172 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 121604732 Common - Catalase Pnap_1830 127 COG0753 KatE, Catalase Inorganic ion transport and metabolism 121606148 Common - single-stranded-DNA-specific exonuclease RecJ Pnap_3258 192 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 121603108 Common - Mg2+ transporter protein, CorA family protein Pnap_0191 99 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 121604992 Common - Carboxymethylenebutenolidase Pnap_2091 115 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 121604980 Common - endonuclease III Pnap_2079 240 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 121605710 Common - fumarylacetoacetate (FAA) hydrolase Pnap_2816 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 121603523 Common - branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein, hypothetical Pnap_0612 7 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 121606040 Nonpathogen - hypothetical protein Pnap_3150 1 None None None 121606580 Common - binding-protein-dependent transport systems inner membrane component Pnap_3692 142 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 121606710 Common - hypothetical protein Pnap_3822 69 COG3000 ERG3, Sterol desaturase Lipid metabolism 121606443 Nonpathogen - hypothetical protein Pnap_3555 1 None None None 121603827 Nonpathogen - hypothetical protein Pnap_0918 1 None None None 121606219 Nonpathogen - hypothetical protein Pnap_3330 1 None None None 121604351 Common - secretion protein HlyD family protein Pnap_1445 143 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 121603947 Common - inner-membrane translocator Pnap_1038 108 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 121604772 Common - type IV pilus biogenesis/stability protein PilW Pnap_1870 79 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 121605721 Common - efflux transporter, RND family, MFP subunit Pnap_2827 148 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 121603600 Common - toluene tolerance family protein Pnap_0689 80 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 121605061 Common - Precorrin-8X methylmutase CbiC/CobH Pnap_2161 118 COG2082 CobH, Precorrin isomerase Coenzyme metabolism 121604119 Common - prevent-host-death family protein Pnap_1212 8 None None None 121604154 Common - hypothetical protein Pnap_1247 18 None None None 121606641 Nonpathogen - hypothetical protein Pnap_3753 10 None None None 121605419 Common phnP carbon-phosphorus lyase complex accessory protein Pnap_2524 94 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 121604015 Common - glucose-1-phosphate adenylyltransferase Pnap_1106 164 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 121605690 Common rpsA 30S ribosomal protein S1 Pnap_2796 221 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 121604642 Common - hypothetical protein Pnap_1738 9 None None None 121605433 Common - alpha/beta hydrolase fold Pnap_2538 56 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 121605390 Common - Lytic transglycosylase, catalytic Pnap_2494 30 None None None 121606161 Common - binding-protein-dependent transport systems inner membrane component Pnap_3271 164 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 121606354 Common - Hemerythrin HHE cation binding domain protein Pnap_3465 15 None None None 121606244 Common - Rubredoxin-type Fe(Cys)4 protein Pnap_3355 112 COG1773 COG1773, Rubredoxin Energy production and conversion 121603366 Common - PAS/PAC sensor signal transduction histidine kinase Pnap_0452 217 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 121603016 Common - metallophosphoesterase Pnap_0099 31 None None None 121605236 Nonpathogen - hypothetical protein Pnap_2337 8 COG1633 COG1633, Uncharacterized conserved protein Function unknown 121603767 Common - hypothetical protein Pnap_0858 59 COG3825 COG3825, Uncharacterized protein conserved in bacteria Function unknown 121603353 Common - CBS domain containing protein Pnap_0439 218 COG4535 CorC, Putative Mg2+ and Co2+ transporter CorC Inorganic ion transport and metabolism 121604112 Common - DNA internalization-related competence protein ComEC/Rec2 Pnap_1205 160 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 121603006 Common - adenylate cyclase Pnap_0089 66 COG3025 COG3025, Uncharacterized conserved protein Function unknown 121605767 Common - transcriptional regulator, LysR family Pnap_2876 190 COG0583 LysR, Transcriptional regulator Transcription 121603130 Common - Redoxin domain protein Pnap_0213 81 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 121604124 Common - transglutaminase domain protein Pnap_1217 106 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 121604743 Common - ABC transporter related Pnap_1841 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 121604756 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Pnap_1854 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 121605514 Common - hypothetical protein Pnap_2620 3 None None None 121603454 Common - hypothetical protein Pnap_0542 25 None None None 121603087 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B Pnap_0170 212 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 121605855 Common - Squalene/phytoene synthase Pnap_2964 113 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 121606166 Common - Sua5/YciO/YrdC/YwlC family protein Pnap_3276 217 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 121606662 Common - coproporphyrinogen III oxidase Pnap_3774 203 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 121604579 Nonpathogen - hypothetical protein Pnap_1674 1 None None None 121606881 Common - transcriptional regulator, TetR family Pnap_3995 89 COG1309 AcrR, Transcriptional regulator Transcription 121605293 Common - putative primosomal replication protein Pnap_2394 22 COG2965 PriB, Primosomal replication protein N DNA replication, recombination, and repair 121605192 Nonpathogen - hypothetical protein Pnap_2292 1 None None None 121606853 Common - putative signal peptide protein Pnap_3966 10 None None None 121605097 Common - ribosomal protein L31 Pnap_2197 127 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 121606914 Common - biotin synthase Pnap_4030 179 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 121604532 Common - hypothetical protein Pnap_1626 23 COG4394 COG4394, Uncharacterized protein conserved in bacteria Function unknown 121606303 Common - Polypeptide-transport-associated domain protein, FtsQ-type Pnap_3414 82 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 121603186 Common - drug resistance transporter, Bcr/CflA subfamily Pnap_0269 226 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 121603441 Common - 5-formyltetrahydrofolate cyclo-ligase Pnap_0528 42 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 121603884 Common ureB urease subunit beta Pnap_0975 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 121606986 Common - Rh family protein/ammonium transporter Pnap_4104 202 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 121604751 Common - GCN5-related N-acetyltransferase Pnap_1849 86 COG2153 ElaA, Predicted acyltransferase General function prediction only 121606745 Common - esterase, PHB depolymerase family Pnap_3857 49 COG3509 LpqC, Poly(3-hydroxybutyrate) depolymerase Secondary metabolites biosynthesis, transport, and catabolism 121603120 Common - ribosomal protein L3 Pnap_0203 229 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 121603855 Common - malonate decarboxylase alpha subunit Pnap_0946 27 COG4670 COG4670, Acyl CoA:acetate/3-ketoacid CoA transferase Lipid metabolism 121603971 Nonpathogen - hypothetical protein Pnap_1062 11 None None None 121604262 Common - protein of unknown function DUF924 Pnap_1355 63 COG3803 COG3803, Uncharacterized protein conserved in bacteria Function unknown 121604516 Common - extracellular solute-binding protein, family 1 Pnap_1610 112 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 121604716 Common - chromosome segregation protein SMC Pnap_1814 176 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 121603701 Common - two component transcriptional regulator, LuxR family Pnap_0790 217 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 121603257 Common rpsM 30S ribosomal protein S13 Pnap_0342 241 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 121604958 Common - ABC transporter related Pnap_2057 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 121604540 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Pnap_1634 161 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 121603338 Common - transposase IS3/IS911 family protein Pnap_0424 4 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 121604437 Common - cation diffusion facilitator family transporter Pnap_1531 219 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 121606041 Common - transposase, IS605 OrfB family Pnap_3151 69 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 121606068 Common - predicted glycosyl transferase Pnap_3178 79 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 121606349 Common - ABC transporter related Pnap_3460 249 COG5265 ATM1, ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components Posttranslational modification, protein turnover, chaperones 121604924 Common - hypothetical protein Pnap_2023 42 COG3651 COG3651, Uncharacterized protein conserved in bacteria Function unknown 121604326 Common - polynucleotide phosphorylase/polyadenylase Pnap_1420 240 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 121603080 Common - protein of unknown function RIO1 Pnap_0163 66 COG1718 RIO1, Serine/threonine protein kinase involved in cell cycle control Signal transduction mechanisms / Cell division and chromosome partitioning 121606233 Common - allantoinase Pnap_3344 187 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 121604508 Common - TRAP dicarboxylate transporter- DctP subunit Pnap_1602 97 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 121604705 Common - ABC transporter domain protein Pnap_1803 243 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 121603307 Common - ATP-dependent metalloprotease FtsH Pnap_0392 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 121604820 Common - LexA repressor Pnap_1918 174 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 121603414 Common - ribosomal protein S9 Pnap_0501 248 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 121604163 Common - hypothetical protein Pnap_1256 4 COG3470 Tpd, Uncharacterized protein probably involved in high-affinity Fe2+ transport Inorganic ion transport and metabolism 121604760 Common - dihydrolipoamide dehydrogenase Pnap_1858 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 121605850 Common - acriflavin resistance protein Pnap_2959 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 121606171 Common - PAS/PAC sensor hybrid histidine kinase Pnap_3281 190 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121604899 Nonpathogen - hypothetical protein Pnap_1998 1 None None None 121605447 Common - PilT protein domain protein Pnap_2552 46 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 121603929 Common - FMN-dependent alpha-hydroxy acid dehydrogenase Pnap_1020 110 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 121605476 Common - hypothetical protein Pnap_2581 62 COG3176 COG3176, Putative hemolysin General function prediction only 121605492 Common - rare lipoprotein A Pnap_2597 135 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 121606935 Common - inner-membrane translocator Pnap_4052 50 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 121603994 Common - putative transmembrane protein Pnap_1085 8 COG5343 COG5343, Uncharacterized protein conserved in bacteria Function unknown 121603280 Nonpathogen - hypothetical protein Pnap_0365 1 None None None 121606315 Common - hypothetical protein Pnap_3426 141 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 121605456 Common - putative iron-regulated protein Pnap_2561 31 COG3487 IrpA, Uncharacterized iron-regulated protein Inorganic ion transport and metabolism 121603073 Nonpathogen - putative glycin-rich signal peptide protein Pnap_0156 1 None None None 121604550 Common - hypothetical protein Pnap_1644 11 None None None 121604925 Nonpathogen - hypothetical protein Pnap_2024 1 None None None 121603209 Common - protein of unknown function DUF820 Pnap_0294 31 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 121604139 Common - integral membrane sensor signal transduction histidine kinase Pnap_1232 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121606390 Common - putative zinc protease protein Pnap_3501 16 COG4324 COG4324, Predicted aminopeptidase General function prediction only 121604668 Common - surface antigen (D15) Pnap_1766 161 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 121605308 Common - pentapeptide repeat protein Pnap_2409 51 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 121603018 Nonpathogen - hypothetical protein Pnap_0101 4 None None None 121604221 Common - Hemerythrin HHE cation binding domain protein Pnap_1314 30 COG5592 COG5592, Uncharacterized conserved protein Function unknown 121605312 Nonpathogen - hypothetical protein Pnap_2413 1 None None None 121604430 Common - putative monovalent cation/H+ antiporter subunit A Pnap_1524 208 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 121605006 Common - hypothetical protein Pnap_2105 17 None None None 121605640 Common - Helix-turn-helix, type 11 domain protein Pnap_2746 17 COG2378 COG2378, Predicted transcriptional regulator Transcription 121606952 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Pnap_4069 174 COG0388 COG0388, Predicted amidohydrolase General function prediction only 121604387 Common - NAD-dependent epimerase/dehydratase Pnap_1481 79 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 121603935 Common - Methyltransferase type 11 Pnap_1026 140 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 121606973 Common - heavy metal translocating P-type ATPase Pnap_4090 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 121604599 Common - CheA signal transduction histidine kinases Pnap_1694 148 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 121603922 Common - protein of unknown function DUF182 Pnap_1013 67 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 121605988 Common - histidine kinase internal region Pnap_3097 101 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 121605701 Common - maleylacetoacetate isomerase Pnap_2807 78 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 121605477 Nonpathogen - hypothetical protein Pnap_2582 1 None None None 121605005 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Pnap_2104 69 COG0388 COG0388, Predicted amidohydrolase General function prediction only 121602920 Common - hypothetical protein Pnap_0002 22 None None None 121603915 Common - cyanophycin synthetase Pnap_1006 87 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 121605440 Common - protein of unknown function DUF541 Pnap_2545 34 COG3471 COG3471, Predicted periplasmic/secreted protein Function unknown 121603782 Common - MaoC domain protein dehydratase Pnap_0873 79 COG2030 MaoC, Acyl dehydratase Lipid metabolism 121605604 Common - putative succinate dehydrogenase Pnap_2710 58 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 121604050 Common - periplasmic solute binding protein Pnap_1142 175 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 121604192 Common - hypothetical protein Pnap_1285 15 None None None 121604199 Common - short-chain dehydrogenase/reductase SDR Pnap_1292 98 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 121606228 Common - DNA repair protein RadC Pnap_3339 177 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 121606766 Common - peptide deformylase Pnap_3878 213 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 121604960 Common - translation initiation factor SUI1 Pnap_2059 86 COG0023 SUI1, Translation initiation factor 1 (eIF-1/SUI1) and related proteins Translation, ribosomal structure and biogenesis 121603137 Common - OmpW family protein Pnap_0220 72 COG3047 OmpW, Outer membrane protein W Cell envelope biogenesis, outer membrane 121604787 Common - cystathionine beta-lyase Pnap_1885 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 121605333 Common - permease for cytosine/purines, uracil, thiamine, allantoin Pnap_2434 18 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 121606207 Nonpathogen - hypothetical protein Pnap_3317 1 None None None 121606268 Common - signal recognition particle protein Pnap_3379 246 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 121605199 Common - Alcohol dehydrogenase GroES domain protein Pnap_2299 196 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 121604715 Common - hypothetical protein Pnap_1813 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 121603998 Common - FolC bifunctional protein Pnap_1089 218 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 121604269 Nonpathogen - hypothetical protein Pnap_1362 4 None None None 121604036 Common - protein-L-isoaspartate(D-aspartate) O-methyltransferase Pnap_1128 159 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 121606340 Common - dihydroorotase Pnap_3451 91 COG0418 PyrC, Dihydroorotase Nucleotide transport and metabolism 121604603 Common - dihydroxy-acid dehydratase Pnap_1698 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 121605538 Common - YcfA family protein Pnap_2644 32 COG1724 COG1724, Predicted periplasmic or secreted lipoprotein Cell motility and secretion 121604692 Common - Mammalian cell entry related domain protein Pnap_1790 11 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 121605449 Common - phosphoserine phosphatase SerB Pnap_2554 153 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 121605948 Common acpS 4'-phosphopantetheinyl transferase Pnap_3057 149 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 121603419 Common - tyrosyl-tRNA synthetase Pnap_0506 240 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 121605432 Common - (p)ppGpp synthetase I, SpoT/RelA Pnap_2537 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 121603727 Common - putative oxygen-independent coproporphyrinogen III oxidase Pnap_0816 205 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 121602952 Common - transglutaminase domain protein Pnap_0034 89 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 121606475 Common - heat shock protein 90 Pnap_3587 151 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 121605115 Common - MscS Mechanosensitive ion channel Pnap_2215 201 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 121606508 Common - acyl-CoA dehydrogenase domain protein Pnap_3620 157 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 121605818 Common - protein of unknown function DUF323 Pnap_2927 87 COG1262 COG1262, Uncharacterized conserved protein Function unknown 121606933 Common - putative ABC transporter Pnap_4050 86 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 121604855 Common - nickel-dependent hydrogenase, large subunit Pnap_1954 100 COG0374 HyaB, Ni,Fe-hydrogenase I large subunit Energy production and conversion 121604557 Common - inner-membrane translocator Pnap_1651 153 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 121605820 Common - putative flavodoxin Pnap_2929 76 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 121603698 Common aspS aspartyl-tRNA synthetase Pnap_0787 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 121604305 Nonpathogen - hypothetical protein Pnap_1399 1 None None None 121606409 Common - inner-membrane translocator Pnap_3520 137 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 121606486 Common - integral membrane sensor signal transduction histidine kinase Pnap_3598 129 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 121603246 Common - ribosomal protein L24 Pnap_0331 209 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 121605945 Nonpathogen - hypothetical protein Pnap_3054 1 None None None 121604233 Common - nitrite reductase, copper-containing Pnap_1326 62 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 121603433 Nonpathogen - hypothetical protein Pnap_0520 1 None None None 121605627 Common - Protocatechuate 4,5-dioxygenase Pnap_2733 31 COG3384 COG3384, Uncharacterized conserved protein Function unknown 121604410 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Pnap_1504 71 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 121605128 Common - molybdenum cofactor synthesis domain Pnap_2228 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 121605660 Common - hypothetical protein Pnap_2766 18 COG4274 COG4274, Uncharacterized conserved protein Function unknown 121606346 Common - polar amino acid ABC transporter, inner membrane subunit Pnap_3457 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 121606429 Common - hypothetical protein Pnap_3540 10 None None None 121603509 Common - FAD linked oxidase domain protein Pnap_0598 32 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 121603341 Common - transposase IS116/IS110/IS902 family protein Pnap_0427 75 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 121606698 Common - HpcH/HpaI aldolase Pnap_3810 99 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 121606099 Common - recombination factor protein RarA Pnap_3209 240 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 121603833 Common - AsmA family protein Pnap_0924 52 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 121603739 Common - hypothetical protein Pnap_0830 13 None None None 121602977 Nonpathogen - hypothetical protein Pnap_0059 3 None None None 121605503 Common - phosphoglucosamine mutase Pnap_2609 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 121604798 Common - CHRD domain containing protein Pnap_1896 15 None None None 121603978 Common - peptide chain release factor 2 Pnap_1069 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 121604338 Common - NADH dehydrogenase subunit I Pnap_1432 190 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 121604526 Common - nicotinate phosphoribosyltransferase Pnap_1620 80 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 121605409 Common - Thioredoxin domain Pnap_2513 72 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 121605808 Common - 3,4-dihydroxy-2-butanone 4-phosphate synthase Pnap_2917 228 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 121604006 Common - Ion transport 2 domain protein Pnap_1097 3 None None None 121606912 Common - 3-demethylubiquinone-9 3-methyltransferase Pnap_4028 64 COG3865 COG3865, Uncharacterized protein conserved in bacteria Function unknown 121604830 Common - protein of unknown function DUF192 Pnap_1928 90 COG1430 COG1430, Uncharacterized conserved protein Function unknown 121605828 Common - pseudouridine synthase Pnap_2937 213 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 121603510 Common - Uncharacterized protein UPF0065 Pnap_0599 65 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121604494 Common - amine oxidase Pnap_1588 44 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 121604951 Common - TolB, N-terminal domain protein Pnap_2050 167 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 121606747 Common - SlyX family protein Pnap_3859 6 COG2900 SlyX, Uncharacterized protein conserved in bacteria Function unknown 121604204 Common - secretion protein HlyD Pnap_1297 60 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 121605077 Common - N-acetylglutamate synthase Pnap_2177 199 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 121603680 Common - dephospho-CoA kinase Pnap_0769 204 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 121604459 Common - MaoC domain protein dehydratase Pnap_1553 90 COG2030 MaoC, Acyl dehydratase Lipid metabolism 121603940 Common - FAD dependent oxidoreductase Pnap_1031 127 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 121606084 Common - exopolysaccharide transport protein family Pnap_3194 172 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 121605975 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Pnap_3084 179 COG0546 Gph, Predicted phosphatases General function prediction only 121604977 Common - putative transcriptional regulator, GntR family Pnap_2076 232 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 121606951 Common - allantoate amidohydrolase Pnap_4068 85 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 121604392 Common - PfkB domain protein Pnap_1486 157 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 121603448 Common - D-fructose-6-phosphate amidotransferase Pnap_0536 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 121606724 Nonpathogen - putative p-cresol methylhydroxylase subunit Pnap_3836 6 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 121603581 Common - Frataxin family protein Pnap_0670 43 COG1965 CyaY, Protein implicated in iron transport, frataxin homolog Inorganic ion transport and metabolism 121605400 Nonpathogen - conjugal transfer protein TrbJ Pnap_2504 1 COG5314 COG5314, Conjugal transfer/entry exclusion protein Intracellular trafficking and secretion 121606626 Common - hypothetical protein Pnap_3738 13 None None None 121604843 Common - hypothetical protein Pnap_1941 10 None None None 121604589 Nonpathogen - hypothetical protein Pnap_1684 1 None None None 121606624 Common - glutathione synthetase Pnap_3736 125 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 121606631 Nonpathogen - hypothetical protein Pnap_3743 1 None None None 121603009 Common - flavin reductase domain protein, FMN-binding Pnap_0092 107 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 121607000 Common - DNA polymerase III, beta subunit Pnap_4118 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 121602949 Common - NADH:flavin oxidoreductase/NADH oxidase Pnap_0031 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 121604183 Common - pseudouridine synthase Pnap_1276 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 121604938 Common - molybdenum ABC transporter, periplasmic molybdate-binding protein Pnap_2037 133 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 121605776 Common - RND efflux system, outer membrane lipoprotein, NodT family Pnap_2885 137 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 121605934 Common - putative transmembrane protein Pnap_3043 32 COG3170 FimV, Tfp pilus assembly protein FimV Cell motility and secretion / Intracellular trafficking and secretion 121603173 Common - ATP synthase F1, epsilon subunit Pnap_0256 168 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 121603663 Common - Trans-hexaprenyltranstransferase Pnap_0752 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 121606564 Common - putative chaperone protein, HscA/DnaK Pnap_3676 38 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 121603466 Common - Acyl-CoA dehydrogenase, type 2, C-terminal domain Pnap_0554 99 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 121604054 Common - ABC transporter related Pnap_1146 246 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 121605963 Common - 3-oxoacyl-(acyl-carrier-protein) reductase Pnap_3072 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 121606400 Common - pantothenate kinase Pnap_3511 123 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 121605522 Common - alanyl-tRNA synthetase Pnap_2628 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 121605190 Common - cysteine desulfurase IscS Pnap_2290 237 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 121606103 Common - thioredoxin reductase Pnap_3213 245 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 121603676 Nonpathogen - hypothetical protein Pnap_0765 3 None None None 121606410 Common - Extracellular ligand-binding receptor Pnap_3521 145 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 121602966 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Pnap_0048 164 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 121603485 Nonpathogen - hypothetical protein Pnap_0573 2 None None None 121605705 Common - ABC-type phosphate/phosphonate transport system periplasmic component Pnap_2811 6 None None None 121605404 Nonpathogen - hypothetical protein Pnap_2508 1 None None None 121603595 Common gltD glutamate synthase subunit beta Pnap_0684 209 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 121604378 Common - guanosine 5'-monophosphate oxidoreductase Pnap_1472 233 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 121606501 Common - putative phenylacetate-CoA ligase Pnap_3613 102 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 121606674 Common - leucyl-tRNA synthetase Pnap_3786 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 121606299 Nonpathogen - hypothetical protein Pnap_3410 3 None None None 121603060 Common - Spore coat U domain protein Pnap_0143 7 COG5430 COG5430, Uncharacterized secreted protein Function unknown 121605819 Common - Pirin domain protein domain protein Pnap_2928 141 COG1741 COG1741, Pirin-related protein General function prediction only 121605208 Common - Chromate transporter Pnap_2308 40 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 121605105 Common - phosphate ABC transporter, inner membrane subunit PstC Pnap_2205 223 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 121603240 Common - Ferritin, Dps family protein Pnap_0325 123 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 121603492 Common - ABC transporter related Pnap_0580 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 121603166 Common - F0F1 ATP synthase subunit A Pnap_0249 153 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 121603864 Common - transcriptional regulator, LysR family Pnap_0955 176 COG0583 LysR, Transcriptional regulator Transcription 121603776 Common - beta-ketoadipyl CoA thiolase Pnap_0867 175 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 121603794 Common - hypothetical protein Pnap_0885 26 None None None 121605306 Common - DEAD/DEAH box helicase domain protein Pnap_2407 240 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 121604253 Common - putative cold-shock DNA-binding domain protein Pnap_1346 16 COG1278 CspC, Cold shock proteins Transcription 121604724 Common - prevent-host-death family protein Pnap_1822 19 None None None 121603237 Common - ATP-dependent DNA helicase RecG Pnap_0322 210 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 121606424 Common - binding-protein-dependent transport systems inner membrane component Pnap_3535 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 121605684 Common - DNA gyrase subunit A Pnap_2790 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 121606653 Common - multi-sensor signal transduction histidine kinase Pnap_3765 149 COG3850 NarQ, Signal transduction histidine kinase, nitrate/nitrite-specific Signal transduction mechanisms 121603898 Common - Endonuclease/exonuclease/phosphatase Pnap_0989 16 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 121604594 Common moaA molybdenum cofactor biosynthesis protein A Pnap_1689 197 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 121604025 Common phhA phenylalanine 4-monooxygenase Pnap_1117 45 COG3186 COG3186, Phenylalanine-4-hydroxylase Amino acid transport and metabolism 121606386 Common - hypothetical protein Pnap_3497 12 None None None 121604283 Common - lipid A biosynthesis acyltransferase Pnap_1376 41 COG4261 COG4261, Predicted acyltransferase General function prediction only 121605929 Common - transcriptional regulator, LysR family Pnap_3038 189 COG0583 LysR, Transcriptional regulator Transcription 121604947 Common - hypothetical protein Pnap_2046 16 None None None 121604063 Common - tRNA delta(2)-isopentenylpyrophosphate transferase Pnap_1155 213 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 121605607 Common - inner-membrane translocator Pnap_2713 146 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 121604076 Common - AMP-dependent synthetase and ligase Pnap_1168 214 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 121605201 Common - heat shock protein Hsp20 Pnap_2301 163 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 121603475 Common - sulfate ABC transporter, periplasmic sulfate-binding protein Pnap_0563 89 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 121605423 Nonpathogen - hypothetical protein Pnap_2528 1 None None None 121606781 Common - MltA domain protein Pnap_3893 93 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 121602991 Common - Acetyl-CoA hydrolase Pnap_0073 95 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 121604446 Common - (Acyl-carrier-protein) phosphodiesterase Pnap_1540 98 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 121604077 Nonpathogen - 17 kDa surface antigen Pnap_1169 1 COG3134 COG3134, Predicted outer membrane lipoprotein Function unknown 121603849 Common - protein-export protein SecB Pnap_0940 108 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 121604081 Common - Auxin Efflux Carrier Pnap_1173 78 COG0679 COG0679, Predicted permeases General function prediction only 121605176 Nonpathogen - hypothetical protein Pnap_2276 1 None None None 121606089 Common - protein of unknown function DUF21 Pnap_3199 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 121606845 Common - two component transcriptional regulator, winged helix family Pnap_3958 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 121604315 Common - putative signal-transduction protein with CBS domains Pnap_1409 175 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 121605834 Common - benzoyl-CoA oxygenase component B Pnap_2943 16 COG3396 COG3396, Uncharacterized conserved protein Function unknown 121606326 Common - dihydrodipicolinate synthetase Pnap_3437 208 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 121603881 Common - Urease accessory protein UreF Pnap_0972 81 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 121605141 Common - hypothetical protein Pnap_2241 4 None None None 121606654 Nonpathogen - hypothetical protein Pnap_3766 1 None None None 121606312 Common - Peptidoglycan glycosyltransferase Pnap_3423 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 121606517 Common - two component transcriptional regulator, Fis family Pnap_3629 177 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 121604150 Common - hemerythrin-like metal-binding protein Pnap_1243 14 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 121606290 Common - protein of unknown function UPF0227 Pnap_3401 54 COG3150 COG3150, Predicted esterase General function prediction only 121605922 Common - UbiC transcription regulator-associated domain protein Pnap_3031 135 COG2188 PhnF, Transcriptional regulators Transcription 121606703 Common - tricarballylate dehydrogenase Pnap_3815 59 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 121606831 Common - FimB Pnap_3943 8 COG3523 IcmF, Uncharacterized protein conserved in bacteria Function unknown 121605659 Common - Silent information regulator protein Sir2 Pnap_2765 138 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 121603984 Common - OmpA/MotB domain protein Pnap_1075 159 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 121606795 Common - Uncharacterized protein UPF0065 Pnap_3907 75 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121605092 Nonpathogen - hypothetical protein Pnap_2192 1 None None None 121603571 Common - S-adenosylmethionine synthetase Pnap_0660 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 121603869 Common - sulphate transporter Pnap_0960 160 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 121606958 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Pnap_4075 152 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 121605656 Common - hypothetical protein Pnap_2762 33 None None None 121605155 Common - hypothetical protein Pnap_2255 2 None None None 121605829 Common - transglutaminase domain protein Pnap_2938 30 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 121605252 Common - OsmC family protein Pnap_2353 87 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 121606524 Common - putative transposase of insertion sequence ISRm10-1 Pnap_3636 41 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 121604478 Common - hypothetical protein Pnap_1572 21 COG4453 COG4453, Uncharacterized protein conserved in bacteria Function unknown 121605596 Common - Xylose isomerase domain protein TIM barrel Pnap_2702 25 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 121603533 Common - NmrA family protein Pnap_0622 87 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 121606738 Common - alkylphosphonate utilization operon protein PhnA Pnap_3850 104 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 121604863 Common - hydrogenase maturation protein HypF Pnap_1962 108 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 121603440 Common - Lytic transglycosylase, catalytic Pnap_0527 160 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 121603374 Common - Rhodanese domain protein Pnap_0460 66 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 121605874 Common - sodium/calcium exchanger membrane region Pnap_2983 106 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 121606862 Nonpathogen - hypothetical protein Pnap_3975 1 None None None 121605220 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Pnap_2320 47 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 121605909 Common - cyclase family protein Pnap_3018 62 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 121602944 Nonpathogen - hypothetical protein Pnap_0026 2 None None None 121606945 Common - ABC transporter related Pnap_4062 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 121603980 Common - CheB methylesterase Pnap_1071 150 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 121603119 Common rpsJ 30S ribosomal protein S10 Pnap_0202 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 121605892 Common - isochorismatase hydrolase Pnap_3001 61 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 121605639 Common - chorismate synthase Pnap_2745 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 121603909 Common - ABC transporter related Pnap_1000 249 COG4674 COG4674, Uncharacterized ABC-type transport system, ATPase component General function prediction only 121605645 Common - GTP-binding protein, HSR1-related Pnap_2751 93 COG1160 COG1160, Predicted GTPases General function prediction only 121606098 Common - inner-membrane translocator Pnap_3208 151 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 121605217 Common - ferredoxin, 2Fe-2S Pnap_2317 75 COG3411 COG3411, Ferredoxin Energy production and conversion 121605241 Nonpathogen - ferredoxin Pnap_2342 11 COG0633 Fdx, Ferredoxin Energy production and conversion 121604341 Common - proton-translocating NADH-quinone oxidoreductase, chain L Pnap_1435 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 121604688 Common - pyridine nucleotide-disulphide oxidoreductase dimerisation region Pnap_1786 118 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 121606498 Common - inner-membrane translocator Pnap_3610 146 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 121606062 Common cysM cysteine synthase B Pnap_3172 221 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 121603805 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Pnap_0896 111 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 121603588 Common - hypothetical protein Pnap_0677 9 None None None 121606514 Common - putative transcriptional regulator, Crp/Fnr family Pnap_3626 29 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 121605620 Common - ABC transporter related Pnap_2726 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 121603132 Common - cytochrome B561 Pnap_0215 60 COG3658 COG3658, Cytochrome b Energy production and conversion 121605747 Common - threonyl-tRNA synthetase Pnap_2854 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 121603049 Common - hypothetical protein Pnap_0132 2 None None None 121604488 Common - aminotransferase, class V Pnap_1582 230 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 121606922 Common - beta alanine--pyruvate transaminase Pnap_4039 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 121603102 Common - putative lipoprotein Pnap_0185 16 COG3218 COG3218, ABC-type uncharacterized transport system, auxiliary component General function prediction only 121604409 Common - TRAP dicarboxylate transporter, DctM subunit Pnap_1503 127 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 121605439 Common - diacylglycerol kinase, catalytic region Pnap_2544 39 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 121604264 Common - hypothetical protein Pnap_1357 29 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 121604095 Common - deoxyuridine 5'-triphosphate nucleotidohydrolase Dut Pnap_1188 179 COG0756 Dut, dUTPase Nucleotide transport and metabolism 121606445 Common - 6-phosphofructokinase Pnap_3557 139 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 121604219 Common - GTP-binding protein, HSR1-related Pnap_1312 99 COG1161 COG1161, Predicted GTPases General function prediction only 121604422 Common - CrcB protein Pnap_1516 33 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 121606596 Common - OstA family protein Pnap_3708 21 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 121606557 Common - OsmC family protein Pnap_3669 89 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 121605994 Nonpathogen - hypothetical protein Pnap_3103 4 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 121606157 Common - hypothetical protein Pnap_3267 36 None None None 121604243 Common - Amidohydrolase 3 Pnap_1336 102 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 121605341 Common - AAA ATPase, central domain protein Pnap_2442 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 121604877 Common - von Willebrand factor, type A Pnap_1976 45 COG4548 NorD, Nitric oxide reductase activation protein Inorganic ion transport and metabolism 121605915 Common - aconitate hydratase Pnap_3024 217 COG1048 AcnA, Aconitase A Energy production and conversion 121603199 Nonpathogen - hypothetical protein Pnap_0284 1 None None None 121606072 Common - putative acetyltransferase Pnap_3182 33 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 121606024 Common - NusG antitermination factor Pnap_3134 38 COG0250 NusG, Transcription antiterminator Transcription 121602982 Common - methyltransferase GidB Pnap_0064 199 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 121603227 Common - hypothetical protein Pnap_0312 19 COG3853 TelA, Uncharacterized protein involved in tellurite resistance Inorganic ion transport and metabolism 121605397 Nonpathogen - Conjugal transfer protein TrbC Pnap_2501 3 COG3838 VirB2, Type IV secretory pathway, VirB2 components (pilins) Intracellular trafficking and secretion 121603657 Common - NUDIX hydrolase Pnap_0746 111 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 121606902 Common - putative transcriptional regulator Pnap_4018 39 COG3636 COG3636, Predicted transcriptional regulator Transcription 121603042 Common glcF glycolate oxidase iron-sulfur subunit Pnap_0125 170 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 121606200 Common - hypothetical protein Pnap_3310 2 None None None 121605149 Common - hypothetical protein Pnap_2249 12 None None None 121604870 Common - hydrogenase-1 expression HyaE Pnap_1969 15 None None None 121605799 Common - hypothetical protein Pnap_2908 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 121606567 Common - Extracellular ligand-binding receptor Pnap_3679 152 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 121605941 Common - lysyl-tRNA synthetase Pnap_3050 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 121605343 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Pnap_2444 6 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 121604809 Common - Extracellular ligand-binding receptor Pnap_1907 129 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 121603743 Common - molybdopterin oxidoreductase Pnap_0834 189 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 121603848 Common - para-aminobenzoate synthase, subunit I Pnap_0939 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 121604631 Common - uracil phosphoribosyltransferase Pnap_1726 165 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 121603919 Common - malic enzyme Pnap_1010 212 COG0281 SfcA, Malic enzyme Energy production and conversion 121605348 Nonpathogen - hypothetical protein Pnap_2449 7 None None None 121606209 Common - conserved hypothetical phage-related protein Pnap_3320 10 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 121605289 Common - hypothetical protein Pnap_2390 6 None None None 121606660 Common - arginase Pnap_3772 146 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 121602963 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Pnap_0045 23 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 121606004 Common - hypothetical protein Pnap_3113 27 COG3385 COG3385, FOG: Transposase and inactivated derivatives DNA replication, recombination, and repair 121606114 Common - acyl-CoA dehydrogenase domain protein Pnap_3224 145 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 121606731 Common pyrF orotidine 5'-phosphate decarboxylase Pnap_3843 77 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 121605229 Common - H+-transporting two-sector ATPase, B/B' subunit Pnap_2330 25 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 121606173 Common - Electron-transferring-flavoprotein dehydrogenase Pnap_3283 105 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 121605183 Common - phage integrase family protein Pnap_2283 143 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 121606053 Common - hypothetical protein Pnap_3163 16 None None None 121603212 Common - formyltetrahydrofolate deformylase Pnap_0297 216 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 121606284 Common - UDP-N-acetylmuramate Pnap_3395 205 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 121603961 Common - transcriptional regulator, TraR/DksA family Pnap_1052 135 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 121604916 Common - binding-protein-dependent transport systems inner membrane component Pnap_2015 220 COG4239 COG4239, ABC-type uncharacterized transport system, permease component General function prediction only 121603219 Nonpathogen - hypothetical protein Pnap_0304 1 None None None 121606964 Common - Uncharacterized protein UPF0065 Pnap_4081 76 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121605632 Common - hypothetical protein Pnap_2738 5 COG4861 COG4861, Uncharacterized protein conserved in bacteria Function unknown 121606331 Common - extracellular solute-binding protein, family 3 Pnap_3442 180 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 121605835 Common - enoyl-CoA hydratase Pnap_2944 33 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 121604722 Common - methionine aminopeptidase, type I Pnap_1820 245 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 121603499 Common - heme exporter protein CcmC Pnap_0587 117 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 121605737 Common - permease Pnap_2844 103 COG0701 COG0701, Predicted permeases General function prediction only 121605527 Common - binding-protein-dependent transport systems inner membrane component Pnap_2633 209 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 121606187 Nonpathogen - phage protein, putative Pnap_3297 1 None None None 121606776 Common - putative transcriptional regulator, AsnC family Pnap_3888 154 COG1522 Lrp, Transcriptional regulators Transcription 121605417 Common - IS66 Orf2 family protein Pnap_2522 52 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 121606521 Common - transposase Pnap_3633 29 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 121603230 Common - hypothetical protein Pnap_0315 6 None None None 121605325 Common - protein of unknown function DUF81 Pnap_2426 82 COG0730 COG0730, Predicted permeases General function prediction only 121606406 Common - protein of unknown function DUF344 Pnap_3517 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 121605668 Common - 2-nitropropane dioxygenase, NPD Pnap_2774 135 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 121605790 Common - N6 adenine-specific DNA methyltransferase protein, N12 class Pnap_2899 25 None None None 121603357 Common glyQ glycyl-tRNA synthetase subunit alpha Pnap_0443 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 121604903 Common - hypothetical protein Pnap_2002 8 None None None 121605057 Common - cobalamin (vitamin B12) biosynthesis CbiG protein Pnap_2157 68 COG2073 CbiG, Cobalamin biosynthesis protein CbiG Coenzyme metabolism 121603380 Common - hypothetical protein Pnap_0466 86 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 121603627 Common - Glutathione S-transferase, N-terminal domain Pnap_0716 118 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 121606235 Common - phosphoribosyltransferase Pnap_3346 109 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 121604110 Common - peptidase C14, caspase catalytic subunit p20 Pnap_1203 24 COG4249 COG4249, Uncharacterized protein containing caspase domain General function prediction only 121606415 Common - Uncharacterized protein UPF0065 Pnap_3526 69 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121606721 Common - ABC transporter related Pnap_3833 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 121604990 Nonpathogen - putative lipase Pnap_2089 3 None None None 121606648 Common - nitrate reductase, beta subunit Pnap_3760 147 COG1140 NarY, Nitrate reductase beta subunit Energy production and conversion 121606502 Common - Uncharacterized protein UPF0065 Pnap_3614 66 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121605259 Common - hypothetical protein Pnap_2360 26 None None None 121605543 Nonpathogen - hypothetical protein Pnap_2649 1 None None None 121603792 Common - putative transmembrane protein Pnap_0883 15 None None None 121606217 Nonpathogen - hypothetical protein Pnap_3328 1 None None None 121603820 Common - phospholipase D/Transphosphatidylase Pnap_0911 135 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 121605246 Common - hypothetical protein Pnap_2347 8 None None None 121606860 Nonpathogen - tolA protein Pnap_3973 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 121603760 Common - binding-protein-dependent transport systems inner membrane component Pnap_0851 113 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 121603379 Common - hypothetical protein Pnap_0465 17 COG5486 COG5486, Predicted metal-binding integral membrane protein Function unknown 121605717 Common - dipeptidyl aminopeptidases/acylaminoacyl-peptidases-like protein Pnap_2823 35 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 121605903 Common - ornithine carbamoyltransferase Pnap_3012 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 121605435 Common - N-formylglutamate amidohydrolase Pnap_2540 52 COG3741 HutG, N-formylglutamate amidohydrolase Amino acid transport and metabolism 121603351 Common - multi-sensor hybrid histidine kinase Pnap_0437 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121604861 Common - hydrogenase expression/formation protein HypD Pnap_1960 109 COG0409 HypD, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 121604649 Common - transposase IS116/IS110/IS902 family protein Pnap_1747 75 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 121603780 Common - ISXo7 transposase Pnap_0871 39 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 121603496 Common - periplasmic protein thiol--disulphide oxidoreductase DsbE Pnap_0584 128 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 121606462 Common - ABC-2 type transporter, NodJ family Pnap_3574 100 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 121603008 Common - PAS/PAC sensor hybrid histidine kinase Pnap_0091 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121604697 Common - putative heat shock protein Pnap_1795 233 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 121605099 Common - MATE efflux family protein Pnap_2199 115 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 121605951 Common - GTP-binding protein Era Pnap_3060 226 COG1159 Era, GTPase General function prediction only 121603069 Common - major facilitator superfamily MFS_1 Pnap_0152 107 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 121603602 Common - ABC transporter related Pnap_0691 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 121603106 Nonpathogen - protein of unknown function DUF1003 Pnap_0189 13 COG4420 COG4420, Predicted membrane protein Function unknown 121604439 Common - diheme cytochrome c Pnap_1533 19 None None None 121603391 Common - pyruvate carboxyltransferase Pnap_0477 179 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 121606051 Common - hypothetical protein Pnap_3161 14 None None None 121603617 Common - twin-arginine translocation protein, TatA/E family subunit Pnap_0706 89 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 121605231 Common - F0F1 ATP synthase subunit A Pnap_2332 199 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 121605991 Common - protein of unknown function DUF497 Pnap_3100 17 COG2929 COG2929, Uncharacterized protein conserved in bacteria Function unknown 121604984 Common - putative transposase of insertion sequence ISRm10-1 Pnap_2083 41 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 121606870 Common - Glutathione S-transferase, N-terminal domain Pnap_3984 99 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 121606712 Nonpathogen - hypothetical protein Pnap_3824 1 None None None 121603958 Common dcd deoxycytidine triphosphate deaminase Pnap_1049 148 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 121605706 Common - putative PAS/PAC sensor protein Pnap_2812 101 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 121605558 Common - aldehyde dehydrogenase Pnap_2664 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 121604046 Common - transposase IS116/IS110/IS902 family protein Pnap_1138 80 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 121605692 Common - hypothetical protein Pnap_2798 7 COG5416 COG5416, Uncharacterized integral membrane protein Function unknown 121605786 Common - peptidyl-prolyl cis-trans isomerase, cyclophilin type Pnap_2895 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 121603261 Common - ribosomal protein L17 Pnap_0346 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 121605594 Common - coenzyme A transferase Pnap_2700 98 COG4670 COG4670, Acyl CoA:acetate/3-ketoacid CoA transferase Lipid metabolism 121606143 Common - heat shock protein DnaJ domain protein Pnap_3253 92 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 121604973 Common - ABC transporter related Pnap_2072 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 121605269 Common - protein of unknown function DUF710 Pnap_2370 25 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 121606867 Common - filamentation induced by cAMP protein Fic Pnap_3980 79 COG3177 COG3177, Uncharacterized conserved protein Function unknown 121605574 Common - sugar transferase Pnap_2680 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 121603684 Common - glutaredoxin-like protein Pnap_0773 126 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 121605998 Common - protease Do Pnap_3107 224 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 121606263 Common - integral membrane sensor signal transduction histidine kinase Pnap_3374 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121603567 Common - protein of unknown function DUF805 Pnap_0656 25 COG3152 COG3152, Predicted membrane protein Function unknown 121603757 Nonpathogen - hypothetical protein Pnap_0848 1 None None None 121604626 Common - 2-isopropylmalate synthase Pnap_1721 213 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 121606877 Common - 3-demethylubiquinone-9 3-methyltransferase Pnap_3991 75 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 121603639 Common - cytochrome c, class I Pnap_0728 29 COG4654 COG4654, Cytochrome c551/c552 Energy production and conversion 121604985 Nonpathogen - hypothetical protein Pnap_2084 3 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 121606074 Common - hypothetical protein Pnap_3184 6 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 121606453 Common - ATPase, P-type (transporting), HAD superfamily, subfamily IC Pnap_3565 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 121603778 Common - Uncharacterized protein UPF0065 Pnap_0869 75 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121605203 Common - protein of unknown function DUF214 Pnap_2303 40 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 121604965 Common - major facilitator superfamily MFS_1 Pnap_2064 49 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 121606587 Common - chromosome replication initiation inhibitor protein Pnap_3699 62 COG0583 LysR, Transcriptional regulator Transcription 121603752 Common - Uncharacterized protein UPF0065 Pnap_0843 70 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121605577 Common - glycine cleavage system T protein Pnap_2683 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 121604092 Common - 2-dehydro-3-deoxyphosphooctonate aldolase Pnap_1184 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 121604104 Common - methyltransferase type 11 Pnap_1197 32 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 121604799 Common - Radical SAM N-terminal domain protein Pnap_1897 73 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 121605666 Common - Thymidylate synthase Pnap_2772 136 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 121605012 Common - 2-chlorobenzoate 1,2-dioxygenase Pnap_2111 26 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 121604520 Common - thioesterase superfamily protein Pnap_1614 40 COG0824 FcbC, Predicted thioesterase General function prediction only 121603420 Common - D-tyrosyl-tRNA deacylase Pnap_0507 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 121606038 Common - Uncharacterized protein UPF0065 Pnap_3148 67 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121605026 Common - acyl-CoA dehydrogenase domain protein Pnap_2125 158 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 121605889 Common - protein of unknown function DUF891 Pnap_2998 23 COG4679 COG4679, Phage-related protein Function unknown 121606205 Common - phage late control D family protein Pnap_3315 37 COG3500 COG3500, Phage protein D General function prediction only 121604654 Common - hypothetical protein Pnap_1752 29 COG3385 COG3385, FOG: Transposase and inactivated derivatives DNA replication, recombination, and repair 121606047 Common - alpha/beta hydrolase fold Pnap_3157 162 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 121604896 Nonpathogen - hypothetical protein Pnap_1995 1 None None None 121606638 Common - glutamate--cysteine ligase Pnap_3750 27 None None None 121604108 Common - DNA topoisomerase IV subunit A Pnap_1201 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 121606272 Common - two component, sigma54 specific, transcriptional regulator, Fis family Pnap_3383 222 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 121604022 Nonpathogen - hypothetical protein Pnap_1114 1 None None None 121605032 Common - electron transfer flavoprotein beta-subunit Pnap_2131 153 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 121606128 Common - protein of unknown function DUF1468 Pnap_3238 25 None None None 121605225 Common - nitrogenase MoFe cofactor biosynthesis protein NifE Pnap_2325 56 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 121604180 Common - protein of unknown function DUF465 Pnap_1273 28 COG2841 COG2841, Uncharacterized protein conserved in bacteria Function unknown 121604503 Common - Galactarate dehydratase Pnap_1597 73 COG2721 UxaA, Altronate dehydratase Carbohydrate transport and metabolism 121604674 Common - Ribonuclease H Pnap_1772 213 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 121604690 Common - glucose sorbosone dehydrogenase Pnap_1788 114 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 121605562 Common - uncharacterized peroxidase-related enzyme Pnap_2668 64 COG2128 COG2128, Uncharacterized conserved protein Function unknown 121603095 Common - ammonium transporter Pnap_0178 202 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 121606110 Common - hypothetical protein Pnap_3220 12 None None None 121606121 Common - Na/Pi-cotransporter II-related protein Pnap_3231 74 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 121606438 Common - protein of unknown function DUF214 Pnap_3550 176 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 121606960 Common - aminoglycoside phosphotransferase Pnap_4077 90 COG3178 COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases General function prediction only 121604868 Common - Rubredoxin-type Fe(Cys)4 protein Pnap_1967 86 COG1773 COG1773, Rubredoxin Energy production and conversion 121605580 Common - peptidylprolyl isomerase, FKBP-type Pnap_2686 136 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 121606555 Common - CinA domain protein Pnap_3667 190 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 121604383 Common - hypothetical protein Pnap_1477 5 None None None 121605616 Nonpathogen - hypothetical protein Pnap_2722 1 None None None 121606617 Common - response regulator receiver protein Pnap_3729 125 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 121604173 Nonpathogen - hypothetical protein Pnap_1266 1 None None None 121603718 Common - transcriptional regulator, MarR family Pnap_0807 84 COG1846 MarR, Transcriptional regulators Transcription 121605470 Common - ISSod10, transposase OrfB Pnap_2575 31 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 121603815 Common - hypothetical protein Pnap_0906 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 121604800 Common - protein of unknown function DUF1294 Pnap_1898 12 COG3326 COG3326, Predicted membrane protein Function unknown 121603314 Nonpathogen - hypothetical protein Pnap_0399 1 None None None 121604810 Common - flavodoxin/nitric oxide synthase Pnap_1908 64 COG0369 CysJ, Sulfite reductase, alpha subunit (flavoprotein) Inorganic ion transport and metabolism 121603255 Common secY preprotein translocase subunit SecY Pnap_0340 218 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 121605371 Common - 5-carboxymethyl-2-hydroxymuconate delta-isomerase Pnap_2474 176 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 121605366 Nonpathogen - hypothetical protein Pnap_2469 1 None None None 121602968 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Pnap_0050 235 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 121603071 Nonpathogen - hypothetical protein Pnap_0154 2 None None None 121605442 Common - integral membrane sensor signal transduction histidine kinase Pnap_2547 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121605864 Common - Ferrochelatase Pnap_2973 169 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 121603593 Common - protein of unknown function DUF1568 Pnap_0682 60 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 121604367 Common - ribosomal protein S16 Pnap_1461 207 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 121605875 Common - lactoylglutathione lyase Pnap_2984 123 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 121603305 Common - hypothetical protein Pnap_0390 8 COG5622 COG5622, Protein required for attachment to host cells Cell motility and secretion 121603644 Common - alpha/beta hydrolase fold Pnap_0733 112 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 121605553 Common - putative PAS/PAC sensor protein Pnap_2659 57 COG4566 TtrR, Response regulator Signal transduction mechanisms 121603482 Common - SMP-30/Gluconolaconase/LRE domain protein Pnap_0570 67 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 121605310 Common - hypothetical protein Pnap_2411 12 None None None 121604927 Common - oxidoreductase domain protein Pnap_2026 183 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 121603877 Nonpathogen - hypothetical protein Pnap_0968 1 None None None 121606530 Common - ribosomal protein L10 Pnap_3642 205 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 121603221 Common - domain of unknown function DUF1745 Pnap_0306 25 COG4398 COG4398, Uncharacterized protein conserved in bacteria Function unknown 121605450 Common - hypothetical protein Pnap_2555 41 COG4949 COG4949, Uncharacterized membrane-anchored protein conserved in bacteria Function unknown 121603437 Common - alpha,alpha-trehalose-phosphate synthase (UDP-forming) Pnap_0524 97 COG0380 OtsA, Trehalose-6-phosphate synthase Carbohydrate transport and metabolism 121603920 Common - Uncharacterized protein UPF0065 Pnap_1011 72 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121605679 Common - 40-residue YVTN family beta-propeller repeat protein Pnap_2785 60 COG3391 COG3391, Uncharacterized conserved protein Function unknown 121603661 Common rpmA 50S ribosomal protein L27 Pnap_0750 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 121606251 Common - RNA-binding S4 domain protein Pnap_3362 110 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 121606980 Common - Hydroxypyruvate isomerase Pnap_4098 77 COG3622 Hfi, Hydroxypyruvate isomerase Carbohydrate transport and metabolism 121602939 Nonpathogen - thiamine biosynthesis protein ThiS Pnap_0021 1 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 121604490 Common - hypothetical protein Pnap_1584 2 None None None 121604273 Common - phospholipid/glycerol acyltransferase Pnap_1366 53 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 121606365 Common - 3-hydroxyacyl-CoA dehydrogenase, NAD-binding Pnap_3476 161 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 121604734 Common - BolA family protein Pnap_1832 58 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 121606342 Common - TRAP dicarboxylate transporter, DctM subunit Pnap_3453 122 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 121604616 Common - conserved hypothetical protein 730 Pnap_1711 107 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 121603903 Common - Uncharacterized conserved small protein-like protein Pnap_0994 17 COG5606 COG5606, Uncharacterized conserved small protein Function unknown 121606212 Nonpathogen - hypothetical protein Pnap_3323 2 COG2378 COG2378, Predicted transcriptional regulator Transcription 121603200 Common - glycosyl transferase, family 2 Pnap_0285 168 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 121603039 Common - SMP-30/Gluconolaconase/LRE domain protein Pnap_0122 74 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 121605479 Common - NAD-dependent epimerase/dehydratase Pnap_2584 65 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 121605290 Common - replicative DNA helicase Pnap_2391 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 121603860 Common - phosphoribosyl-dephospho-CoA transferase Pnap_0951 13 None None None 121603502 Common - cytochrome B561 Pnap_0590 44 COG3658 COG3658, Cytochrome b Energy production and conversion 121606246 Common - glutamate-1-semialdehyde-2,1-aminomutase Pnap_3357 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 121606194 Nonpathogen - hypothetical protein Pnap_3304 1 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 121605869 Common - transcriptional regulator, MarR family Pnap_2978 44 COG1846 MarR, Transcriptional regulators Transcription 121604945 Common - hypothetical protein Pnap_2044 30 None None None 121606948 Common - extracellular solute-binding protein, family 3 Pnap_4065 161 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 121605335 Common - carbohydrate kinase, YjeF related protein Pnap_2436 208 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 121605735 Common - hypothetical protein Pnap_2842 19 None None None 121603148 Common - ABC transporter related Pnap_0231 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 121606769 Common - DNA protecting protein DprA Pnap_3881 210 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 121606136 Common - protein of unknown function DUF58 Pnap_3246 98 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 121603425 Common ruvB Holliday junction DNA helicase B Pnap_0512 234 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 121603010 Common - hypothetical protein Pnap_0093 2 None None None 121604267 Common - protein of unknown function DUF6, transmembrane Pnap_1360 76 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 121604553 Common - putative signal peptide protein Pnap_1647 17 COG3868 COG3868, Uncharacterized conserved protein Function unknown 121605498 Common - inner-membrane translocator Pnap_2604 165 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 121606279 Common - ribosomal protein L11 methyltransferase Pnap_3390 173 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 121606591 Common - DSBA oxidoreductase Pnap_3703 67 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 121603913 Common - Urease accessory protein UreD Pnap_1004 72 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 121604807 Common - inner-membrane translocator Pnap_1905 148 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 121603673 Common - general secretion pathway protein I Pnap_0762 8 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 121605197 Common - beta-lactamase domain protein Pnap_2297 135 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 121605102 Common - phosphate uptake regulator, PhoU Pnap_2202 198 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 121603207 Common - LrgA family protein Pnap_0292 37 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 121604052 Common - ABC transporter related Pnap_1144 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 121603561 Common - porin, Gram-negative type Pnap_0650 36 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 121606337 Common - heat shock protein HtpX Pnap_3448 189 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 121604156 Common - ATPase, P-type (transporting), HAD superfamily, subfamily IC Pnap_1249 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 121604258 Common - glutaminyl-tRNA synthetase Pnap_1351 248 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 121606292 Common - transposase, IS4 family protein Pnap_3403 20 None None None 121603143 Common - periplasmic binding protein/LacI transcriptional regulator Pnap_0226 126 COG1609 PurR, Transcriptional regulators Transcription 121605731 Common - efflux transporter, RND family, MFP subunit Pnap_2837 127 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 121603769 Common - ATPase associated with various cellular activities, AAA_5 Pnap_0860 93 COG0714 COG0714, MoxR-like ATPases General function prediction only 121605008 Common - benzoate transporter Pnap_2107 59 COG3135 BenE, Uncharacterized protein involved in benzoate metabolism Secondary metabolites biosynthesis, transport, and catabolism 121603991 Common - argininosuccinate synthase Pnap_1082 213 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 121604744 Common - 3-hydroxyacyl-CoA dehydrogenase, NAD-binding Pnap_1842 178 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 121605264 Common - cobalbumin biosynthesis enzyme Pnap_2365 128 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 121604785 Common - Adenylosuccinate synthase Pnap_1883 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 121603184 Common - AMP-dependent synthetase and ligase Pnap_0267 219 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 121605857 Common - MltA-interacting MipA family protein Pnap_2966 23 COG3713 OmpV, Outer membrane protein V Cell envelope biogenesis, outer membrane 121602934 Common - NADPH-dependent FMN reductase Pnap_0016 8 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 121603489 Common - ABC nitrate/sulfonate/bicarbonate family transporter, periplasmic ligand binding protein Pnap_0577 47 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 121605512 Nonpathogen - hypothetical protein Pnap_2618 1 None None None 121603100 Common - ABC transporter related Pnap_0183 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 121604769 Common - pseudouridine synthase Pnap_1867 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 121605031 Common - acyl-CoA dehydrogenase domain protein Pnap_2130 160 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 121606600 Common - protein of unknown function DUF132 Pnap_3712 15 COG1569 COG1569, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 121604122 Nonpathogen - hypothetical protein Pnap_1215 2 None None None 121604549 Common - glycosyl transferase, group 1 Pnap_1643 178 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 121606435 Common - RND efflux system, outer membrane lipoprotein, NodT family Pnap_3547 109 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 121606168 Common - tryptophanyl-tRNA synthetase Pnap_3278 222 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 121604260 Common - hypothetical protein Pnap_1353 14 None None None 121605087 Common - HI0933 family protein Pnap_2187 83 COG2081 COG2081, Predicted flavoproteins General function prediction only 121606851 Common - nuclear protein SET Pnap_3964 28 COG2940 COG2940, Proteins containing SET domain General function prediction only 121606396 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pnap_3507 39 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 121603853 Common - GAF modulated sigma54 specific transcriptional regulator, Fis family Pnap_0944 178 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 121604475 Common - cysteine desulfurase IscS Pnap_1569 239 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 121605291 Common - ribosomal protein L9 Pnap_2392 212 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 121604910 Common - tRNA pseudouridine synthase B Pnap_2009 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 121603336 Common - transposase IS66 Pnap_0422 51 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 121606016 Common - DegT/DnrJ/EryC1/StrS aminotransferase Pnap_3126 202 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 121603083 Common - multi-sensor signal transduction histidine kinase Pnap_0166 222 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 121604613 Common - protein of unknown function DUF482 Pnap_1708 81 COG3146 COG3146, Uncharacterized protein conserved in bacteria Function unknown 121606704 Common - transcriptional regulator, LysR family Pnap_3816 187 COG0583 LysR, Transcriptional regulator Transcription 121603416 Common - helicase c2 Pnap_0503 126 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 121603894 Nonpathogen - putative signal transduction protein with EFhand domain Pnap_0985 2 COG5126 FRQ1, Ca2+-binding protein (EF-Hand superfamily) Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only 121605507 Common - protein of unknown function UPF0044 Pnap_2613 89 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 121605769 Common - hypothetical protein Pnap_2878 5 None None None 121606178 Common - phage portal protein, PBSX family Pnap_3288 24 COG5518 COG5518, Bacteriophage capsid portal protein General function prediction only 121604755 Common - transcriptional regulator, Fis family Pnap_1853 19 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 121605723 Common - hypothetical protein Pnap_2829 37 None None None 121603363 Common - response regulator receiver protein Pnap_0449 202 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 121603945 Common - ABC transporter related Pnap_1036 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 121605490 Nonpathogen - hypothetical protein Pnap_2595 1 None None None 121606473 Common - protein of unknown function DUF882 Pnap_3585 64 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 121603937 Common - extracellular solute-binding protein, family 3 Pnap_1028 177 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 121603907 Common - inner-membrane translocator Pnap_0998 149 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 121603695 Common ubiB putative ubiquinone biosynthesis protein UbiB Pnap_0784 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 121606825 Nonpathogen - hypothetical protein Pnap_3937 1 None None None 121603576 Common - ResB family protein Pnap_0665 51 COG1333 ResB, ResB protein required for cytochrome c biosynthesis Posttranslational modification, protein turnover, chaperones 121605977 Common - ribonuclease, Rne/Rng family Pnap_3086 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 121606715 Common - excinuclease ABC, A subunit Pnap_3827 237 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 121604718 Common - DNA ligase, NAD-dependent Pnap_1816 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 121603789 Common - cytochrome C oxidase assembly protein Pnap_0880 68 COG3175 COX11, Cytochrome oxidase assembly factor Posttranslational modification, protein turnover, chaperones 121603157 Common - protein of unknown function DUF6, transmembrane Pnap_0240 46 COG2962 RarD, Predicted permeases General function prediction only 121604822 Common adk adenylate kinase Pnap_1920 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 121606537 Common - Indole-3-glycerol-phosphate synthase Pnap_3649 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 121606080 Common - GDP-mannose 4,6-dehydratase Pnap_3190 226 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 121604165 Common - heavy metal translocating P-type ATPase Pnap_1258 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 121604040 Common - protein of unknown function DUF218 Pnap_1132 60 COG1434 COG1434, Uncharacterized conserved protein Function unknown 121604580 Common - putative signal peptide protein Pnap_1675 47 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 121605402 Nonpathogen - hypothetical protein Pnap_2506 1 COG4643 COG4643, Uncharacterized protein conserved in bacteria Function unknown 121604560 Common - ABC transporter related Pnap_1654 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 121604407 Common - 1-deoxy-D-xylulose-5-phosphate synthase Pnap_1501 228 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 121602978 Common - beta-ketothiolase Pnap_0060 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 121605686 Common - phosphoserine aminotransferase Pnap_2792 102 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 121603282 Common - Roadblock/LC7 family protein Pnap_0367 21 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 121603674 Common - general secretion pathway protein H Pnap_0763 12 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 121605392 Nonpathogen - hypothetical protein Pnap_2496 1 None None None 121604817 Common - 3-hydroxybutyryl-CoA dehydrogenase Pnap_1915 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 121603175 Common - protein of unknown function DUF477 Pnap_0258 87 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 121603643 Common - pyrroloquinoline quinone biosynthesis protein PqqB Pnap_0732 37 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 121606676 Common - MotA/TolQ/ExbB proton channel Pnap_3788 145 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 121603446 Common - UDP-N-acetylglucosamine pyrophosphorylase Pnap_0533 224 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 121603124 Common - ribosomal protein S19 Pnap_0207 248 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 121603273 Common - AAA ATPase, central domain protein Pnap_0358 180 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 121605996 Common - two component transcriptional regulator, winged helix family Pnap_3105 209 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 121606659 Common - ornithine cyclodeaminase Pnap_3771 86 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 121604231 Common - heat shock protein Hsp20 Pnap_1324 116 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 121603716 Common - Uncharacterized protein UPF0065 Pnap_0805 76 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121604291 Common - peptidase U62, modulator of DNA gyrase Pnap_1385 157 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 121606804 Common - protein of unknown function DUF1289 Pnap_3916 17 COG3313 COG3313, Predicted Fe-S protein General function prediction only 121604288 Common - serine O-acetyltransferase Pnap_1382 193 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 121606989 Common - 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family Pnap_4107 102 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 121605505 Common - ATP-dependent metalloprotease FtsH Pnap_2611 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 121605406 Common - Conjugal transfer protein TrbG/VirB9/CagX Pnap_2510 45 COG3504 VirB9, Type IV secretory pathway, VirB9 components Intracellular trafficking and secretion 121603517 Common - amidohydrolase 2 Pnap_0606 53 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 121606975 Common - hypothetical protein Pnap_4092 2 None None None 121605520 Common - Ethanolamine ammonia lyase large subunit Pnap_2626 55 COG4303 EutB, Ethanolamine ammonia-lyase, large subunit Amino acid transport and metabolism 121605643 Nonpathogen - hypothetical protein Pnap_2749 1 None None None 121603002 Nonpathogen - putative transcriptional regulator Pnap_0085 16 COG3636 COG3636, Predicted transcriptional regulator Transcription 121604360 Common - lipoprotein, putative Pnap_1454 36 None None None 121606706 Common - MltA-interacting MipA family protein Pnap_3818 29 COG3713 OmpV, Outer membrane protein V Cell envelope biogenesis, outer membrane 121602997 Common - transposase, IS605 OrfB family Pnap_0079 68 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 121604381 Common - hypothetical protein Pnap_1475 16 None None None 121605353 Common - hemerythrin HHE cation binding region Pnap_2455 22 COG3945 COG3945, Uncharacterized conserved protein Function unknown 121606840 Common sucC succinyl-CoA synthetase subunit beta Pnap_3953 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 121603745 Common - putative lipoprotein Pnap_0836 8 None None None 121603468 Common - response regulator receiver protein Pnap_0556 169 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 121604515 Common - short-chain dehydrogenase/reductase SDR Pnap_1609 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 121606426 Common - extracellular solute-binding protein, family 5 Pnap_3537 182 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 121605174 Nonpathogen - hypothetical protein Pnap_2274 3 None None None 121604079 Common - protein of unknown function UPF0079 Pnap_1171 197 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 121604748 Common - Alcohol dehydrogenase, zinc-binding domain protein Pnap_1846 91 COG2130 COG2130, Putative NADP-dependent oxidoreductases General function prediction only 121606651 Common - major facilitator superfamily MFS_1 Pnap_3763 152 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 121603164 Common - hypothetical protein Pnap_0247 17 COG5615 COG5615, Predicted integral membrane protein Function unknown 121605169 Nonpathogen - hypothetical protein Pnap_2269 1 None None None 121603085 Common pyrE orotate phosphoribosyltransferase Pnap_0168 142 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 121603244 Common - FAD dependent oxidoreductase Pnap_0329 149 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 121604848 Common - aminodeoxychorismate lyase Pnap_1947 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 121603846 Common - nicotinate-nucleotide pyrophosphorylase Pnap_0937 205 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 121603658 Common - hypothetical protein Pnap_0747 13 None None None 121604285 Common - acyl carrier protein Pnap_1379 41 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 121603546 Common - Transglycosylase-associated protein Pnap_0635 21 COG2261 COG2261, Predicted membrane protein Function unknown 121605617 Common - GCN5-related N-acetyltransferase Pnap_2723 35 COG3153 COG3153, Predicted acetyltransferase General function prediction only 121604175 Common - YaeQ family protein Pnap_1268 52 COG4681 COG4681, Uncharacterized protein conserved in bacteria Function unknown 121606407 Common - ABC transporter related Pnap_3518 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 121605103 Common - phosphate ABC transporter, ATPase subunit Pnap_2203 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 121604083 Common - Cyclopropane-fatty-acyl-phospholipid synthase Pnap_1175 125 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 121606998 Common - ribosomal protein L34 Pnap_4116 7 COG0230 RpmH, Ribosomal protein L34 Translation, ribosomal structure and biogenesis 121604726 Common - putative transposase of insertion sequence ISRm10-1 Pnap_1824 41 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 121605172 Nonpathogen - hypothetical protein Pnap_2272 1 None None None 121603210 Nonpathogen - hypothetical protein Pnap_0295 1 None None None 121604889 Common - fructose-1,6-bisphosphate aldolase Pnap_1988 153 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 121605609 Common - ABC transporter related Pnap_2715 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 121605132 Common - aminotransferase AlaT Pnap_2232 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 121604331 Common - NADH-quinone oxidoreductase, B subunit Pnap_1425 191 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 121605927 Common - protein of unknown function DUF339 Pnap_3036 7 COG2938 COG2938, Uncharacterized conserved protein Function unknown 121604729 Common - OmpW family protein Pnap_1827 52 COG3047 OmpW, Outer membrane protein W Cell envelope biogenesis, outer membrane 121604605 Common - transcriptional regulator, GntR family Pnap_1700 112 COG1802 GntR, Transcriptional regulators Transcription 121605064 Common - Auxin Efflux Carrier Pnap_2164 33 COG0679 COG0679, Predicted permeases General function prediction only 121605460 Nonpathogen - hypothetical protein Pnap_2565 1 None None None 121603879 Common - phage integrase family protein Pnap_0970 101 COG0582 XerC, Integrase DNA replication, recombination, and repair 121604070 Common - Hydantoinase B/oxoprolinase Pnap_1162 92 COG0146 HyuB, N-methylhydantoinase B/acetone carboxylase, alpha subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 121606628 Common - hypothetical protein Pnap_3740 23 None None None 121603490 Common - binding-protein-dependent transport systems inner membrane component Pnap_0578 174 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 121603183 Common - hypothetical protein Pnap_0266 4 None None None 121605812 Common - thioesterase superfamily protein Pnap_2921 133 COG0824 FcbC, Predicted thioesterase General function prediction only 121605548 Nonpathogen - hypothetical protein Pnap_2654 2 None None None 121604240 Common - cytochrome B561 Pnap_1333 89 COG3038 CybB, Cytochrome B561 Energy production and conversion 121606163 Common - Asp/Glu racemase Pnap_3273 39 COG4126 COG4126, Hydantoin racemase Amino acid transport and metabolism 121606899 Nonpathogen - hypothetical protein Pnap_4015 2 None None None 121603093 Common - Peptidoglycan glycosyltransferase Pnap_0176 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 121605118 Common - aldehyde dehydrogenase Pnap_2218 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 121605536 Common - Sel1 domain protein repeat-containing protein Pnap_2642 19 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 121603507 Nonpathogen - hypothetical protein Pnap_0596 1 None None None 121603573 Common - lipid A biosynthesis acyltransferase Pnap_0662 93 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 121603239 Common - transcriptional regulator, LysR family Pnap_0324 192 COG0583 LysR, Transcriptional regulator Transcription 121603067 Common - integral membrane sensor signal transduction histidine kinase Pnap_0150 215 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121605374 Common - DSBA oxidoreductase Pnap_2478 39 COG3917 NahD, 2-hydroxychromene-2-carboxylate isomerase Secondary metabolites biosynthesis, transport, and catabolism 121605826 Common - protein of unknown function DUF6, transmembrane Pnap_2935 26 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 121604369 Common - tRNA (guanine-N1)-methyltransferase Pnap_1463 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 121605467 Common - protein of unknown function DUF336 Pnap_2572 46 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 121603737 Common - hypothetical protein Pnap_0828 8 None None None 121603891 Common - C4-dicarboxylate transporter DctA Pnap_0982 162 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 121604778 Common - small GTP-binding protein Pnap_1876 230 COG1160 COG1160, Predicted GTPases General function prediction only 121605917 Common - hypothetical protein Pnap_3026 11 None None None 121603484 Common - cytochrome c, class I Pnap_0572 61 COG2863 COG2863, Cytochrome c553 Energy production and conversion 121605139 Common - glycoside hydrolase, family 24 Pnap_2239 33 COG3772 COG3772, Phage-related lysozyme (muraminidase) General function prediction only 121604746 Common - gluconate 5-dehydrogenase Pnap_1844 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 121605920 Common - HpcH/HpaI aldolase Pnap_3029 98 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 121603732 Common - putative sigma 54 modulation protein/ribosomal protein S30EA Pnap_0821 22 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 121606399 Common - protein of unknown function UPF0089 Pnap_3510 28 COG4908 COG4908, Uncharacterized protein containing a NRPS condensation (elongation) domain General function prediction only 121606377 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Pnap_3488 167 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 121604066 Common - conserved hypothetical protein; putative signal peptide Pnap_1158 15 COG4313 COG4313, Protein involved in meta-pathway of phenol degradation Energy production and conversion 121602971 Common - acetyl-CoA hydrolase/transferase Pnap_0053 99 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 121604832 Common - isocitrate dehydrogenase Pnap_1930 222 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 121604399 Common - regulatory protein, LacI Pnap_1493 125 COG1609 PurR, Transcriptional regulators Transcription 121606606 Common - NAD+ synthetase Pnap_3718 202 COG0171 NadE, NAD synthase Coenzyme metabolism 121603636 Common - beta-lactamase domain protein Pnap_0725 47 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 121605079 Nonpathogen - hypothetical protein Pnap_2179 6 None None None 121603512 Common - 6-phosphogluconate dehydrogenase, NAD-binding Pnap_0601 23 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 121605847 Common clpX ATP-dependent protease ATP-binding subunit Pnap_2956 243 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 121605943 Common - Patatin Pnap_3052 55 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 121605016 Common - hemerythrin-like metal-binding protein Pnap_2115 19 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 121604829 Common - Superoxide dismutase Pnap_1927 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 121604412 Common - protein of unknown function DUF323 Pnap_1506 81 COG1262 COG1262, Uncharacterized conserved protein Function unknown 121605443 Common - 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Pnap_2548 187 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 121605629 Common - transcriptional regulator, LysR family Pnap_2735 133 COG0583 LysR, Transcriptional regulator Transcription 121603689 Common - FAD linked oxidase domain protein Pnap_0778 182 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 121606491 Common - K+-transporting ATPase, B subunit Pnap_3603 232 COG2216 KdpB, High-affinity K+ transport system, ATPase chain B Inorganic ion transport and metabolism 121606384 Common - poly(hydroxyalkanoate) granule-associated protein Pnap_3495 17 COG3937 COG3937, Uncharacterized conserved protein Function unknown 121606550 Common - putative site-specific recombinase transmembrane protein Pnap_3662 23 COG4389 COG4389, Site-specific recombinase DNA replication, recombination, and repair 121602958 Common - binding-protein-dependent transport systems inner membrane component Pnap_0040 183 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 121604964 Nonpathogen - hypothetical protein Pnap_2063 2 None None None 121603835 Common - carboxyl-terminal protease Pnap_0926 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 121604559 Common - ABC transporter related Pnap_1653 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 121606931 Common - response regulator receiver sensor signal transduction histidine kinase Pnap_4048 221 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 121604972 Common - extracellular solute-binding protein, family 3 Pnap_2071 176 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 121604621 Common - RNA polymerase factor sigma-70 Pnap_1716 29 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 121605346 Common - hypothetical protein Pnap_2447 13 None None None 121604390 Common - zinc/iron permease Pnap_1484 21 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 121605877 Common - phosphogluconate dehydratase Pnap_2986 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 121604979 Common - NAD-glutamate dehydrogenase Pnap_2078 76 COG2902 COG2902, NAD-specific glutamate dehydrogenase Amino acid transport and metabolism 121605274 Common - polyhydroxyalkanoate depolymerase, intracellular Pnap_2375 44 COG4553 DepA, Poly-beta-hydroxyalkanoate depolymerase Lipid metabolism 121603403 Common - ribosomal RNA methyltransferase RrmJ/FtsJ Pnap_0490 130 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 121602942 Common - hypothetical protein Pnap_0024 3 None None None 121604876 Common - hydrogenase (NiFe) small subunit HydA Pnap_1975 77 COG1740 HyaA, Ni,Fe-hydrogenase I small subunit Energy production and conversion 121603917 Common - hypothetical protein Pnap_1008 14 None None None 121604496 Common - GntR domain protein Pnap_1590 145 COG2186 FadR, Transcriptional regulators Transcription 121604306 Common - HI0933 family protein Pnap_1400 142 COG2081 COG2081, Predicted flavoproteins General function prediction only 121603439 Common - HAD-superfamily hydrolase, subfamily IIB Pnap_0526 87 COG1877 OtsB, Trehalose-6-phosphatase Carbohydrate transport and metabolism 121604457 Common - 2-dehydropantoate 2-reductase Pnap_1551 116 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 121604202 Common - transcriptional regulator, LysR family Pnap_1295 183 COG0583 LysR, Transcriptional regulator Transcription 121605045 Nonpathogen - hypothetical protein Pnap_2145 1 None None None 121603586 Common - Pilus assembly protein, PilQ Pnap_0675 37 COG3168 PilP, Tfp pilus assembly protein PilP Cell motility and secretion / Intracellular trafficking and secretion 121605622 Common - inner-membrane translocator Pnap_2728 98 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 121606383 Common - short chain dehydrogenase Pnap_3494 237 COG3320 COG3320, Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 121604056 Common - hypothetical protein Pnap_1148 3 None None None 121605147 Common - hypothetical protein Pnap_2247 11 None None None 121606594 Nonpathogen - hypothetical protein Pnap_3706 5 None None None 121606754 Common - intracellular protease, PfpI family Pnap_3866 122 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 121606813 Common - hypothetical protein Pnap_3925 7 None None None 121607002 Common - DNA-directed DNA polymerase Pnap_4120 186 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 121604245 Common - isochorismatase hydrolase Pnap_1338 74 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 121605797 Common - Lytic transglycosylase, catalytic Pnap_2906 52 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 121603034 Common - methionine synthase Pnap_0117 167 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 121604633 Common - hypothetical protein Pnap_1728 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 121603328 Common - ABC transporter related Pnap_0413 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 121605488 Common - acriflavin resistance protein Pnap_2593 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 121606189 Common - phage virion morphogenesis protein Pnap_3299 15 None None None 121603621 Common - protein of unknown function DUF34 Pnap_0710 76 COG0327 COG0327, Uncharacterized conserved protein Function unknown 121606733 Common - ribosomal-protein-alanine acetyltransferase Pnap_3845 162 COG0456 RimI, Acetyltransferases General function prediction only 121602998 Common - efflux transporter, RND family, MFP subunit Pnap_0080 167 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 121606897 Common - Polypeptide-transport-associated domain protein, ShlB-type Pnap_4013 59 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 121604794 Common - cytochrome c, class I Pnap_1892 19 COG4654 COG4654, Cytochrome c551/c552 Energy production and conversion 121603398 Common - major facilitator superfamily MFS_1 Pnap_0485 127 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 121605014 Nonpathogen - hypothetical protein Pnap_2113 1 None None None 121604004 Common - zinc finger, SWIM-type Pnap_1095 39 COG4279 COG4279, Uncharacterized conserved protein Function unknown 121606022 Common - exopolysaccharide transport protein family Pnap_3132 156 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 121606907 Nonpathogen - hypothetical protein Pnap_4023 1 None None None 121603269 Common - allantoate amidohydrolase Pnap_0354 87 COG3195 COG3195, Uncharacterized protein conserved in bacteria Function unknown 121606059 Common - valyl-tRNA synthetase Pnap_3169 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 121604425 Common - monovalent cation/proton antiporter, MnhG/PhaG subunit Pnap_1519 23 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 121603578 Common - putative sulfite oxidase subunit YedY Pnap_0667 125 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 121603628 Common - ClpXP protease specificity-enhancing factor Pnap_0717 64 COG2969 SspB, Stringent starvation protein B General function prediction only 121605894 Common - hypothetical protein Pnap_3003 59 COG2912 COG2912, Uncharacterized conserved protein Function unknown 121604448 Common - protein of unknown function DUF1234 Pnap_1542 57 COG3545 COG3545, Predicted esterase of the alpha/beta hydrolase fold General function prediction only 121606577 Common - extracellular solute-binding protein, family 1 Pnap_3689 57 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 121602984 Common - Cobyrinic acid a,c-diamide synthase Pnap_0066 205 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 121605185 Common - ferredoxin, 2Fe-2S type, ISC system Pnap_2285 58 COG0633 Fdx, Ferredoxin Energy production and conversion 121603048 Common - alanine racemase Pnap_0131 198 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 121606984 Common metX homoserine O-acetyltransferase Pnap_4102 133 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 121605778 Common - efflux transporter, RND family, MFP subunit Pnap_2887 146 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 121606180 Common - phage capsid scaffolding Pnap_3290 22 None None None 121606681 Common - PTS IIA-like nitrogen-regulatory protein PtsN Pnap_3793 137 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 121605279 Common - protein of unknown function DUF218 Pnap_2380 69 COG1434 COG1434, Uncharacterized conserved protein Function unknown 121603870 Common - peptidase S14, ClpP Pnap_0961 166 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 121603191 Common - 2-hydroxy-3-oxopropionate reductase Pnap_0274 187 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 121604251 Common - hypothetical protein Pnap_1344 2 None None None 121604030 Common - L-carnitine dehydratase/bile acid-inducible protein F Pnap_1122 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 121605399 Common - CagE, TrbE, VirB component of type IV transporter system Pnap_2503 63 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 121606966 Common - peptidase M20 Pnap_4083 99 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 121603217 Common - fumarylacetoacetate (FAA) hydrolase Pnap_0302 81 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 121603321 Common - conserved repeat domain Pnap_0406 22 None None None 121606532 Common - ribosomal protein L11 Pnap_3644 248 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 121603028 Common - threonine dehydratase Pnap_0111 204 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 121606324 Common - Diaminopimelate epimerase Pnap_3435 201 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 121606460 Common - hypothetical protein Pnap_3572 13 COG3915 COG3915, Uncharacterized protein conserved in bacteria Function unknown 121605094 Common - RecB family exonuclease-like protein Pnap_2194 40 COG2887 COG2887, RecB family exonuclease DNA replication, recombination, and repair 121605157 Common - phage terminase GpA Pnap_2257 36 COG5525 COG5525, Bacteriophage tail assembly protein General function prediction only 121605150 Nonpathogen - hypothetical protein Pnap_2250 1 None None None 121606413 Common - methylmalonyl-CoA mutase, large subunit Pnap_3524 110 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 121604317 Common - major facilitator superfamily MFS_1 Pnap_1411 167 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 121605413 Nonpathogen - hypothetical protein Pnap_2517 2 None None None 121606032 Common - penicillin-binding protein 1C Pnap_3142 199 COG4953 PbpC, Membrane carboxypeptidase/penicillin-binding protein PbpC Cell envelope biogenesis, outer membrane 121606210 Nonpathogen - hypothetical protein Pnap_3321 1 None None None 121605657 Common - Uncharacterized protein UPF0065 Pnap_2763 73 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121606539 Common - Threonine aldolase Pnap_3651 82 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 121606112 Common - phosphoribosylglycinamide formyltransferase Pnap_3222 220 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 121603555 Common - threonine dehydratase, biosynthetic Pnap_0644 218 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 121603296 Common - hypothetical protein Pnap_0381 8 COG3305 COG3305, Predicted membrane protein Function unknown 121603387 Common - enoyl-CoA hydratase Pnap_0473 177 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 121605059 Common - precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit Pnap_2159 114 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 121605519 Common - ethanolamine transproter Pnap_2625 183 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 121604842 Common - esterase, PHB depolymerase family Pnap_1940 30 COG3509 LpqC, Poly(3-hydroxybutyrate) depolymerase Secondary metabolites biosynthesis, transport, and catabolism 121603982 Common - multi-sensor hybrid histidine kinase Pnap_1073 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121605654 Common - transcriptional regulator, LysR family Pnap_2760 191 COG0583 LysR, Transcriptional regulator Transcription 121604060 Common - phosphate transporter Pnap_1152 172 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 121605689 Common - bifunctional 3-phosphoshikimate 1-carboxyvinyltransferase/cytidine monophosphate kinase Pnap_2795 242 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 121604041 Common - acyl-CoA dehydrogenase domain protein Pnap_1133 160 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 121604353 Common - luciferase family protein Pnap_1447 111 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 121606847 Common - peptidase C26 Pnap_3960 114 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 121606069 Common - acyltransferase 3 Pnap_3179 87 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 121604569 Common - hypothetical protein Pnap_1663 43 COG4717 COG4717, Uncharacterized conserved protein Function unknown 121604321 Common - response regulator receiver and ANTAR domain protein Pnap_1415 97 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 121603807 Common - ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5 Pnap_0898 188 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 121605749 Common - hypothetical protein Pnap_2857 5 None None None 121606888 Common - transcriptional regulator, LysR family Pnap_4004 105 COG0583 LysR, Transcriptional regulator Transcription 121603458 Common - ABC transporter related Pnap_0546 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 121605910 Common - kynureninase Pnap_3019 78 COG3844 COG3844, Kynureninase Amino acid transport and metabolism 121603451 Common - Serine O-acetyltransferase Pnap_0539 191 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 121605851 Common - efflux transporter, RND family, MFP subunit Pnap_2960 154 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 121605884 Common - Chromosomal replication initiator, DnaA Pnap_2993 139 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 121605050 Common - cob(I)alamin adenosyltransferase Pnap_2150 142 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 121605254 Nonpathogen - hypothetical protein Pnap_2355 1 None None None 121606064 Common - NUDIX hydrolase Pnap_3174 13 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 121605215 Common - Electron-transferring-flavoprotein dehydrogenase Pnap_2315 158 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 121603615 Common - putative transmembrane protein Pnap_0704 10 COG3671 COG3671, Predicted membrane protein Function unknown 121606338 Common - putative transmembrane protein Pnap_3449 13 None None None 121605754 Common - extracellular solute-binding protein, family 1 Pnap_2862 124 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 121606512 Common - hypothetical protein Pnap_3624 3 COG3134 COG3134, Predicted outer membrane lipoprotein Function unknown 121606669 Common - cytochrome c oxidase, cbb3-type, subunit II Pnap_3781 82 COG2993 CcoO, Cbb3-type cytochrome oxidase, cytochrome c subunit Energy production and conversion 121606924 Common - TRAP dicarboxylate transporter, DctP subunit Pnap_4041 107 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 121605388 Nonpathogen - hypothetical protein Pnap_2492 1 None None None 121606947 Common - polar amino acid ABC transporter, inner membrane subunit Pnap_4064 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 121604343 Common - NADH dehydrogenase subunit N Pnap_1437 210 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 121606469 Common - hypothetical protein Pnap_3581 33 None None None 121604093 Common - CTP synthetase Pnap_1185 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 121605179 Nonpathogen - hypothetical protein Pnap_2279 1 None None None 121606092 Common - DEAD/DEAH box helicase domain protein Pnap_3202 236 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 121603986 Common - ybaK/ebsC protein Pnap_1077 121 COG2606 EbsC, Uncharacterized conserved protein Function unknown 121604324 Common - aspartate aminotransferase Pnap_1418 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 121606105 Common - ribosomal protein L33 Pnap_3215 129 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 121604037 Common - transcriptional regulator, TetR family Pnap_1129 43 COG1309 AcrR, Transcriptional regulator Transcription 121605694 Common - rfaE bifunctional protein Pnap_2800 148 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 121605420 Common - protein of unknown function DUF6, transmembrane Pnap_2525 9 COG2510 COG2510, Predicted membrane protein Function unknown 121604152 Common - putative ABC transporter ATP-binding protein Pnap_1245 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 121605162 Common - hypothetical protein Pnap_2262 3 None None None 121603943 Common - aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding Pnap_1034 110 COG4631 XdhB, Xanthine dehydrogenase, molybdopterin-binding subunit B Nucleotide transport and metabolism 121604766 Common - putative transmembrane protein Pnap_1864 124 COG4105 ComL, DNA uptake lipoprotein General function prediction only 121606858 Nonpathogen - hypothetical protein Pnap_3971 1 None None None 121605638 Common - short chain dehydrogenase Pnap_2744 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 121606748 Common - Extracellular ligand-binding receptor Pnap_3860 133 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 121606063 Common - transposase, IS605 OrfB Pnap_3173 58 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 121603364 Common - multi-sensor signal transduction histidine kinase Pnap_0450 221 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 121604255 Common - retron reverse transcriptase Pnap_1348 36 None None None 121605664 Common - membrane protein-like protein Pnap_2770 21 COG3308 COG3308, Predicted membrane protein Function unknown 121605495 Common - PfkB domain protein Pnap_2601 126 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 121603488 Nonpathogen - hypothetical protein Pnap_0576 3 COG3746 OprP, Phosphate-selective porin Inorganic ion transport and metabolism 121604547 Nonpathogen - hypothetical protein Pnap_1641 1 None None None 121603787 Common - cytochrome c oxidase, subunit II Pnap_0878 139 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 121603817 Common ppnK inorganic polyphosphate/ATP-NAD kinase Pnap_0908 237 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 121604368 Common - 16S rRNA processing protein RimM Pnap_1462 183 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 121605680 Common - pseudouridine synthase Pnap_2786 116 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 121604295 Common - HI0933-like protein Pnap_1389 46 COG2081 COG2081, Predicted flavoproteins General function prediction only 121605205 Common - UspA domain protein Pnap_2305 36 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 121604225 Common - hypothetical protein Pnap_1318 16 None None None 121604531 Common - elongation factor P Pnap_1625 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 121606666 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Pnap_3778 85 COG0348 NapH, Polyferredoxin Energy production and conversion 121604444 Common - 2-nitropropane dioxygenase, NPD Pnap_1538 99 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 121603139 Common - putative esterase Pnap_0222 31 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 121604525 Common - peptidylprolyl isomerase, FKBP-type Pnap_1619 151 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 121603705 Nonpathogen - hypothetical protein Pnap_0794 1 None None None 121605318 Common - aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein Pnap_2419 98 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 121605438 Common - metallophosphoesterase Pnap_2543 39 COG1409 Icc, Predicted phosphohydrolases General function prediction only 121605451 Nonpathogen - HNH nuclease Pnap_2556 1 None None None 121604571 Common - cytochrome c, class I Pnap_1665 40 COG2863 COG2863, Cytochrome c553 Energy production and conversion 121604995 Common - cytochrome c, class I Pnap_2094 70 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 121606741 Common - hypothetical protein Pnap_3853 20 None None None 121604792 Common - RNA methyltransferase, TrmH family, group 3 Pnap_1890 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 121604159 Nonpathogen - hypothetical protein Pnap_1252 5 None None None 121604504 Common - aldehyde dehydrogenase Pnap_1598 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 121605621 Common - ABC transporter related Pnap_2727 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 121606367 Common - transcriptional regulator, TetR family Pnap_3478 34 COG1309 AcrR, Transcriptional regulator Transcription 121604943 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Pnap_2042 50 COG0748 HugZ, Putative heme iron utilization protein Inorganic ion transport and metabolism 121604536 Common - transcriptional regulator, LysR family Pnap_1630 132 COG0583 LysR, Transcriptional regulator Transcription 121606345 Common - polar amino acid ABC transporter, inner membrane subunit Pnap_3456 176 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 121603564 Common - glucose-6-phosphate 1-dehydrogenase Pnap_0653 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 121604462 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Pnap_1556 30 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 121604470 Common - ferredoxin, 2Fe-2S type, ISC system Pnap_1564 84 COG0633 Fdx, Ferredoxin Energy production and conversion 121604232 Common - phosphoesterase, DHHA1 Pnap_1325 11 COG2404 COG2404, Predicted phosphohydrolase (DHH superfamily) General function prediction only 121606077 Common - glycosyl transferase, family 2 Pnap_3187 62 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 121606175 Common - acyl-CoA dehydrogenase domain protein Pnap_3285 145 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 121605900 Common - ribosomal protein S20 Pnap_3009 26 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 121604434 Common - putative transcriptional regulator Pnap_1528 13 COG1733 COG1733, Predicted transcriptional regulators Transcription 121606886 Common - putative transcriptional regulator, MerR family Pnap_4002 122 COG0789 SoxR, Predicted transcriptional regulators Transcription 121604936 Nonpathogen - hypothetical protein Pnap_2035 3 None None None 121602930 Common - hypothetical protein Pnap_0012 43 COG0392 COG0392, Predicted integral membrane protein Function unknown 121604824 Common - protein of unknown function DUF343 Pnap_1922 99 COG2835 COG2835, Uncharacterized conserved protein Function unknown 121605473 Common - protein-L-isoaspartate O-methyltransferase Pnap_2578 150 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 121605297 Common - Tetratricopeptide TPR_2 repeat protein Pnap_2398 37 COG0457 NrfG, FOG: TPR repeat General function prediction only 121604454 Common - amidohydrolase 2 Pnap_1548 40 COG3618 COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 121604664 Common - undecaprenyl diphosphate synthase Pnap_1762 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 121606571 Common - malate synthase G Pnap_3683 70 COG2225 AceB, Malate synthase Energy production and conversion 121603279 Nonpathogen - hypothetical protein Pnap_0364 3 None None None 121604042 Common - transcriptional regulator, LysR family Pnap_1134 180 COG0583 LysR, Transcriptional regulator Transcription 121606761 Common - pyruvate kinase Pnap_3873 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 121605762 Common - Enoyl-CoA hydratase/isomerase Pnap_2871 180 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 121604701 Nonpathogen - hypothetical protein Pnap_1799 5 COG5455 COG5455, Predicted integral membrane protein Function unknown 121605878 Common - OmpA/MotB domain protein Pnap_2987 10 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 121603859 Common - malonate decarboxylase gamma subunit Pnap_0950 22 None None None 121605358 Common - extracellular ligand-binding receptor Pnap_2460 130 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 121603058 Common - putative transposase of insertion sequence ISRm10-1 Pnap_0141 41 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 121604167 Common - blue (type 1) copper domain protein Pnap_1260 41 COG4454 COG4454, Uncharacterized copper-binding protein Inorganic ion transport and metabolism 121604128 Common - Enoyl-CoA hydratase/isomerase Pnap_1221 180 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 121606918 Nonpathogen - hypothetical protein Pnap_4035 3 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 121606162 Common - transcriptional regulator, GntR family Pnap_3272 129 COG1802 GntR, Transcriptional regulators Transcription 121605472 Common - peptidase M23B Pnap_2577 186 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 121603355 Common - transcriptional regulator, LysR family Pnap_0441 176 COG0583 LysR, Transcriptional regulator Transcription 121605304 Nonpathogen - hypothetical protein Pnap_2405 3 None None None 121606310 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase Pnap_3421 208 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 121605984 Common - glycosyltransferase 36 Pnap_3093 45 COG3459 COG3459, Cellobiose phosphorylase Carbohydrate transport and metabolism 121603836 Common - phosphoglycerate mutase 1 family Pnap_0927 160 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 121603861 Common - acyl transferase domain protein Pnap_0952 207 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 121603956 Common - guanine deaminase Pnap_1047 140 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 121606236 Common - Holliday junction resolvase YqgF Pnap_3347 71 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 121606487 Common - TonB-dependent receptor Pnap_3599 65 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 121603746 Common - formate dehydrogenase, gamma subunit Pnap_0837 68 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 121603845 Common - aspartate alpha-decarboxylase Pnap_0936 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 121604662 Common pyrH uridylate kinase Pnap_1760 244 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 121606569 Common - SpoVT/AbrB domain protein Pnap_3681 6 COG4456 VagC, Virulence-associated protein and related proteins Function unknown 121606707 Common - single-strand binding protein Pnap_3819 212 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 121606019 Common - oxidoreductase domain protein Pnap_3129 70 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 121604334 Common - NADH-quinone oxidoreductase, E subunit Pnap_1428 156 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 121603762 Common - hypothetical protein Pnap_0853 12 None None None 121603692 Common - ubiquinone/menaquinone biosynthesis methyltransferases Pnap_0781 219 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 121606864 Common - hypothetical protein Pnap_3977 34 COG1569 COG1569, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 121606786 Common - (Glutamate--ammonia-ligase) adenylyltransferase Pnap_3898 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 121605166 Nonpathogen - hypothetical protein Pnap_2266 1 None None None 121603174 Common - protein of unknown function DUF477 Pnap_0257 51 COG3762 COG3762, Predicted membrane protein Function unknown 121604011 Common - 4-alpha-glucanotransferase Pnap_1102 119 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 121605110 Common - hypothetical protein Pnap_2210 10 None None None 121605123 Common - death-on-curing family protein Pnap_2223 57 COG3654 Doc, Prophage maintenance system killer protein General function prediction only 121605337 Common - ribonuclease R Pnap_2438 192 COG0557 VacB, Exoribonuclease R Transcription 121606844 Common - transcriptional regulator, MarR family Pnap_3957 8 COG1846 MarR, Transcriptional regulators Transcription 121603284 Common - ABC transporter related Pnap_0369 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 121605635 Nonpathogen - hypothetical protein Pnap_2741 3 COG3678 CpxP, P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein Intracellular trafficking and secretion / Cell motility and secretio / Signal transduction mechanisms / Inorganic ion transport and metabolism 121606319 Nonpathogen - hypothetical protein Pnap_3430 1 None None None 121604451 Common - sulfate ABC transporter, inner membrane subunit CysW Pnap_1545 222 COG4208 CysW, ABC-type sulfate transport system, permease component Inorganic ion transport and metabolism 121606304 Common - D-alanine--D-alanine ligase Pnap_3415 214 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 121605905 Nonpathogen - hypothetical protein Pnap_3014 4 None None None 121605266 Common - cobyrinic acid a,c-diamide synthase Pnap_2367 136 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 121605458 Common - periplasmic lipoprotein-like protein Pnap_2563 15 COG3489 COG3489, Predicted periplasmic lipoprotein General function prediction only 121606202 Nonpathogen - phage P2 GpE family protein Pnap_3312 1 None None None 121606694 Common - transcriptional regulator, LysR family Pnap_3806 192 COG0583 LysR, Transcriptional regulator Transcription 121603622 Common - 4-hydroxythreonine-4-phosphate dehydrogenase Pnap_0711 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 121603911 Common - ABC transporter related Pnap_1002 248 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 121606188 Common - P2 phage tail completion R family protein Pnap_3298 17 None None None 121606797 Common - Alcohol dehydrogenase, zinc-binding domain protein Pnap_3909 176 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 121605715 Common - beta-lactamase domain protein Pnap_2821 91 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 121603272 Common - protein of unknown function DUF989 Pnap_0357 34 COG3748 COG3748, Predicted membrane protein Function unknown 121604376 Common - oligoribonuclease Pnap_1470 88 COG1949 Orn, Oligoribonuclease (3'->5' exoribonuclease) RNA processing and modification 121605195 Nonpathogen - hypothetical protein Pnap_2295 4 None None None 121603133 Common - cytochrome c, class II Pnap_0216 36 COG3909 COG3909, Cytochrome c556 Energy production and conversion 121605733 Common - cation diffusion facilitator family transporter Pnap_2839 193 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 121604783 Nonpathogen - hypothetical protein Pnap_1881 3 COG3242 COG3242, Uncharacterized protein conserved in bacteria Function unknown 121606034 Common - salicylate hydroxylase Pnap_3144 70 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 121605962 Common - acyl carrier protein Pnap_3071 210 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 121605523 Common - putative transcriptional regulator, GntR family Pnap_2629 223 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 121603146 Common - binding-protein-dependent transport systems inner membrane component Pnap_0229 142 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 121603395 Common - DNA polymerase III subunit epsilon Pnap_0481 88 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 121603205 Common - protein of unknown function DUF583 Pnap_0290 27 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 121604849 Common - dTMP kinase Pnap_1948 223 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 121604929 Common - Protocatechuate 4,5-dioxygenase Pnap_2028 18 None None None 121603154 Common - PTS system fructose subfamily IIA component Pnap_0237 64 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 121606822 Nonpathogen - hypothetical protein Pnap_3934 1 None None None 121606270 Common - hypothetical protein Pnap_3381 15 None None None 121606894 Common - hypothetical protein Pnap_4010 13 None None None 121604372 Common - hypothetical protein Pnap_1466 33 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 121604574 Common - hypothetical protein Pnap_1669 36 None None None 121603479 Common - efflux transporter, RND family, MFP subunit Pnap_0567 154 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 121605914 Common - monooxygenase, FAD-binding Pnap_3023 62 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 121604678 Common - transcription elongation factor GreA Pnap_1776 204 COG0782 GreA, Transcription elongation factor Transcription 121603607 Common - Histidinol dehydrogenase Pnap_0696 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 121605362 Common - Proline dehydrogenase Pnap_2465 41 COG0506 PutA, Proline dehydrogenase Amino acid transport and metabolism 121605446 Common - virulence-associated protein VapB-like protein Pnap_2551 13 COG4456 VagC, Virulence-associated protein and related proteins Function unknown 121606335 Common - FAD dependent oxidoreductase Pnap_3446 81 COG2509 COG2509, Uncharacterized FAD-dependent dehydrogenases General function prediction only 121604955 Common - lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA Pnap_2054 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 121606636 Common - C4-dicarboxylate transporter DctA Pnap_3748 161 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 121603738 Common - NLP/P60 protein Pnap_0829 121 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 121605586 Common - oxidoreductase, molybdopterin binding Pnap_2692 82 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 121604834 Common - RNP-1 like RNA-binding protein Pnap_1932 66 COG0724 COG0724, RNA-binding proteins (RRM domain) General function prediction only 121605703 Nonpathogen - hypothetical protein Pnap_2809 1 None None None 121604137 Common - Alcohol dehydrogenase, zinc-binding domain protein Pnap_1230 207 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 121602928 Common - hypothetical protein Pnap_0010 15 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 121606805 Common - Integral membrane protein TerC Pnap_3917 51 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 121606999 Common - chromosomal replication initiator protein DnaA Pnap_4117 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 121603764 Common - GAF sensor hybrid histidine kinase Pnap_0855 209 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121605759 Common - GCN5-related N-acetyltransferase Pnap_2867 59 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 121605271 Common - ribonuclease activity regulator protein RraA Pnap_2372 66 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 121603754 Common - Citrate synthase Pnap_0845 188 COG0372 GltA, Citrate synthase Energy production and conversion 121606618 Common - hypothetical protein Pnap_3730 10 None None None 121603926 Common - Uncharacterized protein UPF0065 Pnap_1017 69 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121606265 Common - two component, sigma54 specific, transcriptional regulator, Fis family Pnap_3376 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 121606252 Common - translation-associated GTPase Pnap_3363 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 121604482 Common - iron-sulfur cluster assembly accessory protein Pnap_1576 149 COG0316 IscA, Uncharacterized conserved protein Function unknown 121606602 Nonpathogen - hypothetical protein Pnap_3714 1 None None None 121605018 Common - Uncharacterized protein UPF0065 Pnap_2117 76 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121606645 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Pnap_3757 94 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 121604522 Common - inner-membrane translocator Pnap_1616 135 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 121605322 Common - hypothetical protein Pnap_2423 72 COG2924 COG2924, Uncharacterized protein conserved in bacteria Function unknown 121603116 Common - 30S ribosomal protein S7 Pnap_0199 238 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 121603055 Common - DNA repair protein RadA Pnap_0138 203 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 121603785 Common - biotin synthesis protein BioC Pnap_0876 66 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 121604301 Common - transposase IS116/IS110/IS902 family protein Pnap_1395 81 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 121606414 Common - hypothetical protein Pnap_3525 5 None None None 121606138 Nonpathogen - hypothetical protein Pnap_3248 1 None None None 121605328 Common - Phosphoadenylyl-sulfate reductase (thioredoxin) Pnap_2429 162 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 121606827 Common - histone-like nucleoid-structuring protein H-NS Pnap_3939 10 COG2916 Hns, DNA-binding protein H-NS General function prediction only 121606471 Common - ErfK/YbiS/YcfS/YnhG family protein Pnap_3583 89 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 121605568 Common - FAD dependent oxidoreductase Pnap_2674 64 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 121605070 Common - permease YjgP/YjgQ family protein Pnap_2170 72 COG0795 COG0795, Predicted permeases General function prediction only 121604638 Common - Maf-like protein Pnap_1734 193 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 121606241 Common - putative CheW protein Pnap_3352 18 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 121606126 Common - protein of unknown function DUF6, transmembrane Pnap_3236 78 COG2962 RarD, Predicted permeases General function prediction only 121605563 Nonpathogen - hypothetical protein Pnap_2669 1 None None None 121604088 Common - hypothetical protein Pnap_1180 28 COG4320 COG4320, Uncharacterized protein conserved in bacteria Function unknown 121605024 Common - short-chain dehydrogenase/reductase SDR Pnap_2123 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 121603967 Common - transposase, IS605 OrfB family Pnap_1058 70 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 121605145 Common - hypothetical protein Pnap_2245 6 None None None 121606879 Common - Pirin domain protein domain protein Pnap_3993 146 COG1741 COG1741, Pirin-related protein General function prediction only 121603610 Common - imidazole glycerol phosphate synthase, glutamine amidotransferase subunit Pnap_0699 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 121605244 Common nifH nitrogenase reductase Pnap_2345 75 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 121604645 Common - transposase Pnap_1743 29 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 121603532 Common - transcriptional regulator, HxlR family Pnap_0621 128 COG1733 COG1733, Predicted transcriptional regulators Transcription 121604215 Common - glutamate--cysteine ligase Pnap_1308 58 COG2918 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 121606553 Common - thiamine-monophosphate kinase Pnap_3665 182 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 121603190 Common - transport-associated Pnap_0273 60 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 121605555 Common - Carboxymuconolactone decarboxylase Pnap_2661 93 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 121604895 Common - putative adenylate/guanylate cyclase Pnap_1994 58 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 121603572 Common - lipid A biosynthesis acyltransferase Pnap_0661 116 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 121604890 Common - Integrase, catalytic region Pnap_1989 25 None None None 121606357 Common - metal dependent phosphohydrolase Pnap_3468 174 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 121603896 Common - protein of unknown function UPF0118 Pnap_0987 163 COG0628 PerM, Predicted permease General function prediction only 121606608 Common - hypothetical protein Pnap_3720 12 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 121603867 Common - hypothetical protein Pnap_0958 15 None None None 121606039 Common - hypothetical protein Pnap_3149 7 None None None 121604018 Common - lipopolysaccharide heptosyltransferase I Pnap_1109 86 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 121604005 Common - SNF2-related protein Pnap_1096 139 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 121605610 Common - ABC transporter related Pnap_2716 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 121604469 Common - excinuclease ABC subunit B Pnap_1563 235 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 121603390 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Pnap_0476 226 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 121604804 Common - beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family Pnap_1902 85 COG1414 IclR, Transcriptional regulator Transcription 121606131 Common - hypothetical protein Pnap_3241 11 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 121603382 Common - Ion transport 2 domain protein Pnap_0468 19 None None None 121605541 Common - phage transcriptional regulator, AlpA Pnap_2647 8 COG3311 AlpA, Predicted transcriptional regulator Transcription 121604905 Common - cyclase/dehydrase Pnap_2004 102 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 121604293 Common - GatB/Yqey domain protein Pnap_1387 150 COG1610 COG1610, Uncharacterized conserved protein Function unknown 121603023 Common - integral membrane sensor hybrid histidine kinase Pnap_0106 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121605779 Common - transcriptional regulator, TetR family Pnap_2888 92 COG1309 AcrR, Transcriptional regulator Transcription 121605063 Common - precorrin-4 C11-methyltransferase Pnap_2163 184 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 121604275 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase Pnap_1368 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 121605729 Common - ABC transporter related Pnap_2835 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 121603852 Common - Hydantoinase/oxoprolinase Pnap_0943 103 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 121606225 Common - threonine dehydratase Pnap_3336 160 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 121604140 Common - two component transcriptional regulator, winged helix family Pnap_1233 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 121603629 Common - hypothetical protein Pnap_0718 8 None None None 121606541 Common - Chorismate mutase Pnap_3653 35 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 121603537 Nonpathogen - hypothetical protein Pnap_0626 1 None None None 121603350 Common - response regulator receiver protein Pnap_0436 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 121604115 Common - transglutaminase, N-terminal domain protein Pnap_1208 86 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 121604694 Nonpathogen - hypothetical protein Pnap_1792 1 None None None 121606018 Common - putative acetyltransferase WbpD Pnap_3128 198 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 121602995 Common - twitching motility protein Pnap_0077 181 COG5008 PilU, Tfp pilus assembly protein, ATPase PilU Cell motility and secretion / Intracellular trafficking and secretion 121606248 Common - transcriptional regulator, Fis family Pnap_3359 94 COG2901 Fis, Factor for inversion stimulation Fis, transcriptional activator Transcription / DNA replication, recombination, and repair 121606144 Nonpathogen - mucin-associated surface protein (MASP) Pnap_3254 1 None None None 121606584 Common - hypothetical protein Pnap_3696 31 COG4095 COG4095, Uncharacterized conserved protein Function unknown 121606872 Common - transglutaminase domain protein Pnap_3986 91 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 121603346 Common - hypothetical protein Pnap_0432 12 None None None 121606155 Nonpathogen - hypothetical protein Pnap_3265 1 None None None 121606774 Common - preprotein translocase, YajC subunit Pnap_3886 149 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 121605130 Common - threonine synthase Pnap_2230 148 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 121603316 Common - putative transcriptional regulator, GntR family Pnap_0401 215 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 121603377 Common - aminotransferase, class V Pnap_0463 22 None None None 121606561 Common - hypothetical protein Pnap_3673 5 None None None 121606925 Common - TRAP dicarboxylate transporter, DctP subunit Pnap_4042 109 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 121603682 Common - protein of unknown function DUF329 Pnap_0771 63 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 121605970 Common - protein of unknown function DUF177 Pnap_3079 55 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 121606008 Common - DegT/DnrJ/EryC1/StrS aminotransferase Pnap_3118 201 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 121606087 Nonpathogen - hypothetical protein Pnap_3197 1 None None None 121604656 Common - Transposase and inactivated derivatives-like protein Pnap_1754 73 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 121604982 Common - phosphoenolpyruvate synthase Pnap_2081 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 121605058 Common - precorrin-2 C20-methyltransferase Pnap_2158 118 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 121606647 Common - nitrate reductase molybdenum cofactor assembly chaperone Pnap_3759 53 COG2180 NarJ, Nitrate reductase delta subunit Energy production and conversion 121603123 Common rplB 50S ribosomal protein L2 Pnap_0206 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 121604228 Common - transposase, IS605 OrfB family Pnap_1321 8 None None None 121605426 Common - conserved hypothetical conjugal transfer protein TraF Pnap_2531 23 COG4959 TraF, Type IV secretory pathway, protease TraF Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 121604174 Common - Ion transport protein Pnap_1267 86 COG1226 Kch, Kef-type K+ transport systems, predicted NAD-binding component Inorganic ion transport and metabolism 121606057 Nonpathogen - hypothetical protein Pnap_3167 15 None None None 121605644 Common - hypothetical protein Pnap_2750 6 COG3596 COG3596, Predicted GTPase General function prediction only 121603619 Common - Sec-independent protein translocase, TatC subunit Pnap_0708 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 121605137 Nonpathogen - hypothetical protein Pnap_2237 1 None None None 121604121 Common - KWG Leptospira repeat protein Pnap_1214 21 None None None 121604067 Common - beta-ketothiolase Pnap_1159 168 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 121602923 Common - NnrUfamily protein Pnap_0005 32 COG4094 COG4094, Predicted membrane protein Function unknown 121605575 Common - response regulator receiver protein Pnap_2681 99 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 121604242 Common - pseudouridine synthase Pnap_1335 203 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 121605781 Common - tRNA(Ile)-lysidine synthetase Pnap_2890 204 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 121606927 Common - integral membrane sensor signal transduction histidine kinase Pnap_4044 194 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 121603779 Common - protein of unknown function UPF0126 Pnap_0870 132 COG2860 COG2860, Predicted membrane protein Function unknown 121605232 Nonpathogen - hypothetical protein Pnap_2333 10 None None None 121606368 Common - acetylglutamate kinase Pnap_3479 219 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 121605239 Nonpathogen - hypothetical protein Pnap_2340 2 None None None 121606277 Common - PfkB domain protein Pnap_3388 169 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 121606358 Common - hypothetical protein Pnap_3469 50 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 121603821 Common - GTP cyclohydrolase I Pnap_0912 175 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 121603887 Common - integral membrane sensor hybrid histidine kinase Pnap_0978 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121603037 Common - nitrogen regulatory protein P-II Pnap_0120 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 121604853 Common - Ankyrin Pnap_1952 112 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 121606820 Nonpathogen - hypothetical protein Pnap_3932 1 None None None 121603634 Common - ABC-2 type transporter Pnap_0723 146 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 121605879 Common - ChaC family protein Pnap_2988 40 COG3703 ChaC, Uncharacterized protein involved in cation transport Inorganic ion transport and metabolism 121606433 Common - pyridine nucleotide-disulphide oxidoreductase dimerisation region Pnap_3544 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 121605224 Common - nitrogenase molybdenum-iron cofactor biosynthesis protein NifN Pnap_2324 49 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 121605256 Common - Redoxin domain protein Pnap_2357 40 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 121606185 Nonpathogen - hypothetical protein Pnap_3295 2 None None None 121604311 Common - nitrite reductase (NAD(P)H), small subunit Pnap_1405 65 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 121605642 Common - hypothetical protein Pnap_2748 5 COG1159 Era, GTPase General function prediction only 121603799 Nonpathogen - hypothetical protein Pnap_0890 1 None None None 121606388 Common - conserved hypothetical protein 374 Pnap_3499 5 COG0392 COG0392, Predicted integral membrane protein Function unknown 121603125 Common - ribosomal protein L22 Pnap_0208 220 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 121606371 Common - NAD-dependent epimerase/dehydratase Pnap_3482 208 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 121603389 Common - Carbamoyl-phosphate synthase L chain, ATP-binding Pnap_0475 233 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 121606954 Common - malic enzyme Pnap_4071 212 COG0281 SfcA, Malic enzyme Energy production and conversion 121604363 Common - Lipocalin family protein Pnap_1457 71 COG3040 Blc, Bacterial lipocalin Cell envelope biogenesis, outer membrane 121606543 Common - putative lipoprotein transmembrane Pnap_3655 18 None None None 121604421 Common - hemerythrin HHE cation binding region Pnap_1515 12 COG3945 COG3945, Uncharacterized conserved protein Function unknown 121605080 Common - acriflavin resistance protein Pnap_2180 174 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 121603722 Common - Guanylate kinase Pnap_0811 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 121605285 Common - hypothetical protein Pnap_2386 71 COG2718 COG2718, Uncharacterized conserved protein Function unknown 121603987 Common - protein of unknown function DUF205 Pnap_1078 168 COG0344 COG0344, Predicted membrane protein Function unknown 121606941 Common - peptidase M24 Pnap_4058 217 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 121606961 Common - protein of unknown function DUF558 Pnap_4078 185 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 121605709 Common - Uncharacterized protein UPF0065 Pnap_2815 60 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121602931 Common - cardiolipin synthase 2 Pnap_0013 134 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 121606100 Common - outer membrane lipoprotein carrier protein LolA Pnap_3210 66 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 121603406 Common - hypothetical protein Pnap_0493 37 COG1510 COG1510, Predicted transcriptional regulators Transcription 121603895 Common - hypothetical protein Pnap_0986 2 None None None 121606849 Common - ApbE family lipoprotein Pnap_3962 135 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 121603553 Common - Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Pnap_0642 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 121604359 Common - major facilitator superfamily MFS_1 Pnap_1453 47 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 121603801 Common - peptidase M16 domain protein Pnap_0892 188 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 121603500 Common - heme exporter protein CcmB Pnap_0588 82 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 121606511 Common - Endoribonuclease L-PSP Pnap_3623 111 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 121605652 Common - O-acetylhomoserine aminocarboxypropyltransferase Pnap_2758 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 121606493 Common - putative transcriptional regulator, Crp/Fnr family Pnap_3605 42 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 121604322 Common - putative metalloendopeptidase, glycoprotease family Pnap_1416 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 121605344 Common - hypothetical protein Pnap_2445 6 None None None 121606085 Common - protein tyrosine phosphatase Pnap_3195 116 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 121606572 Common - haloacid dehalogenase, type II Pnap_3684 64 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 121603045 Common - Glutathione peroxidase Pnap_0128 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 121603293 Common - hypothetical protein Pnap_0378 7 None None None 121603443 Nonpathogen - hypothetical protein Pnap_0530 2 None None None 121603777 Common - short-chain dehydrogenase/reductase SDR Pnap_0868 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 121603541 Common - DNA/RNA non-specific endonuclease Pnap_0630 31 COG1864 NUC1, DNA/RNA endonuclease G, NUC1 Nucleotide transport and metabolism 121604658 Common - D-amino-acid dehydrogenase Pnap_1756 109 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 121603135 Common - hypothetical protein Pnap_0218 25 None None None 121604888 Common - Phosphoglycerate kinase Pnap_1987 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 121603326 Nonpathogen - hypothetical protein Pnap_0411 3 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 121606322 Common - phage integrase family protein Pnap_3433 224 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 121604562 Common - Xylose isomerase domain protein TIM barrel Pnap_1656 28 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 121605831 Common - 3-hydroxybutyryl-CoA dehydrogenase Pnap_2940 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 121605043 Common - hypothetical protein Pnap_2143 33 COG3777 COG3777, Uncharacterized conserved protein Function unknown 121604247 Common - protein of unknown function DUF1211 Pnap_1340 31 COG3548 COG3548, Predicted integral membrane protein Function unknown 121606288 Common - peptidase U62, modulator of DNA gyrase Pnap_3399 169 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 121604740 Common - inner-membrane translocator Pnap_1838 143 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 121604345 Common - NUDIX hydrolase Pnap_1439 152 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 121606811 Nonpathogen - hypothetical protein Pnap_3923 2 None None None 121606381 Nonpathogen - lipopolysaccharide biosynthesis Pnap_3492 2 COG3944 COG3944, Capsular polysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 121606028 Nonpathogen - hypothetical protein Pnap_3138 1 None None None 121602948 Common - two component transcriptional regulator, winged helix family Pnap_0030 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 121603938 Common - polar amino acid ABC transporter, inner membrane subunit Pnap_1029 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 121604057 Common - hypothetical protein Pnap_1149 4 None None None 121603141 Common - periplasmic binding protein/LacI transcriptional regulator Pnap_0224 127 COG1609 PurR, Transcriptional regulators Transcription 121604161 Common - hypothetical protein Pnap_1254 6 None None None 121603519 Common - hypothetical protein Pnap_0608 17 COG4313 COG4313, Protein involved in meta-pathway of phenol degradation Energy production and conversion 121604440 Common - cytochrome B561 Pnap_1534 39 COG3658 COG3658, Cytochrome b Energy production and conversion 121603902 Common - protein of unknown function DUF1016 Pnap_0993 49 COG4804 COG4804, Uncharacterized conserved protein Function unknown 121605912 Common - protein of unknown function DUF1449 Pnap_3021 14 None None None 121605795 Common - protein of unknown function DUF748 Pnap_2904 43 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 121605525 Common - spermidine/putrescine ABC transporter ATPase subunit Pnap_2631 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 121606118 Common - bifunctional riboflavin kinase/FMN adenylyltransferase Pnap_3228 209 COG0196 RibF, FAD synthase Coenzyme metabolism 121603495 Common - cytochrome C biogenesis protein Pnap_0583 91 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 121603599 Common - VacJ family lipoprotein Pnap_0688 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 121606664 Common - hypothetical protein Pnap_3776 11 None None None 121606717 Common - extracellular solute-binding protein, family 5 Pnap_3829 193 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 121604867 Common - HupJ, contains rubredoxin domain Pnap_1966 17 None None None 121602986 Common - parB-like partition proteins Pnap_0068 186 COG1475 Spo0J, Predicted transcriptional regulators Transcription 121605591 Common - protein of unknown function DUF182 Pnap_2697 115 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 121606604 Common - prevent-host-death family protein Pnap_3716 19 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 121606802 Common - adenylosuccinate lyase Pnap_3914 232 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 121606107 Common - Fmu (Sun) domain protein Pnap_3217 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 121603432 Common - protein of unknown function DUF185 Pnap_0519 88 COG1565 COG1565, Uncharacterized conserved protein Function unknown 121603633 Common - hypothetical protein Pnap_0722 19 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 121604147 Common - putative transposase of insertion sequence ISRm10-1 Pnap_1240 41 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 121605633 Common - integral membrane sensor signal transduction histidine kinase Pnap_2739 212 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121604039 Common - regulatory protein, LacI Pnap_1131 125 COG1609 PurR, Transcriptional regulators Transcription 121603548 Common - protein of unknown function DUF894, DitE Pnap_0637 145 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 121606968 Common - integral membrane sensor signal transduction histidine kinase Pnap_4085 132 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 121603839 Common - preprotein translocase subunit SecB Pnap_0930 108 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 121604811 Common - ISSod10, transposase OrfB Pnap_1909 28 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 121606892 Common - transposase Pnap_4008 38 None None None 121606441 Nonpathogen - hypothetical protein Pnap_3553 1 None None None 121604086 Common - transferase hexapeptide repeat Pnap_1178 205 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 121606518 Common - integral membrane sensor signal transduction histidine kinase Pnap_3630 222 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 121605382 Common - Rieske (2Fe-2S) domain protein Pnap_2486 92 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 121604912 Common - translation initiation factor IF-2 Pnap_2011 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 121605180 Common - hypothetical protein Pnap_2280 3 None None None 121605355 Common - ABC transporter related Pnap_2457 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 121605463 Common - TonB family protein Pnap_2568 50 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 121606755 Nonpathogen - hypothetical protein Pnap_3867 1 None None None 121606807 Common - peptidase M48, Ste24p Pnap_3919 129 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 121603645 Common - beta-lactamase domain protein Pnap_0734 56 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 121605896 Common - TonB-dependent receptor Pnap_3005 116 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 121606735 Common - D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase Pnap_3847 103 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 121606316 Common - hypothetical protein Pnap_3427 11 None None None 121606192 Common - Baseplate J family protein Pnap_3302 36 COG3948 COG3948, Phage-related baseplate assembly protein General function prediction only 121606520 Common - sun protein Pnap_3632 207 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 121604630 Common aat leucyl/phenylalanyl-tRNA--protein transferase Pnap_1725 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 121603679 Common - Prepilin peptidase Pnap_0768 139 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 121604513 Common - gamma-glutamyltransferase Pnap_1607 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 121604427 Common - putative monovalent cation/H+ antiporter subunit E Pnap_1521 61 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 121606791 Nonpathogen - hypothetical protein Pnap_3903 1 None None None 121605052 Common - hypothetical protein Pnap_2152 79 COG3411 COG3411, Ferredoxin Energy production and conversion 121606909 Common - globin family protein Pnap_4025 44 COG2346 COG2346, Truncated hemoglobins General function prediction only 121603770 Common - cytochrome c, class I Pnap_0861 61 COG2863 COG2863, Cytochrome c553 Energy production and conversion 121606259 Common - channel protein, hemolysin III family Pnap_3370 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 121606779 Common - protein of unknown function DUF839 Pnap_3891 69 COG3211 PhoX, Predicted phosphatase General function prediction only 121604032 Common - transcriptional regulator, LysR family Pnap_1124 179 COG0583 LysR, Transcriptional regulator Transcription 121606599 Common - putative RNA methylase Pnap_3711 131 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 121605213 Common - electron transfer flavoprotein beta-subunit Pnap_2313 152 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 121605288 Common - peptidase M14, carboxypeptidase A Pnap_2389 21 COG2866 COG2866, Predicted carboxypeptidase Amino acid transport and metabolism 121603865 Common - L-aspartate oxidase Pnap_0956 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 121606066 Common - sugar transferase Pnap_3176 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 121606428 Common - regulatory protein GntR, HTH Pnap_3539 137 COG2186 FadR, Transcriptional regulators Transcription 121606585 Common - transcriptional regulator, LysR family Pnap_3697 121 COG0583 LysR, Transcriptional regulator Transcription 121603077 Common - aldehyde dehydrogenase Pnap_0160 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 121605469 Common - transposase and inactivated derivative Pnap_2574 7 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 121606029 Common - phage shock protein A, PspA Pnap_3139 41 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 121605462 Common - hypothetical protein Pnap_2567 10 COG2906 Bfd, Bacterioferritin-associated ferredoxin Inorganic ion transport and metabolism 121602960 Common - methylglyoxal synthase Pnap_0042 88 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 121604873 Common - Ni/Fe-hydrogenase, b-type cytochrome subunit Pnap_1972 48 COG1969 HyaC, Ni,Fe-hydrogenase I cytochrome b subunit Energy production and conversion 121605824 Common - FAD dependent oxidoreductase Pnap_2933 45 COG3380 COG3380, Predicted NAD/FAD-dependent oxidoreductase General function prediction only 121605040 Common - MmgE/PrpD family protein Pnap_2140 52 COG2079 PrpD, Uncharacterized protein involved in propionate catabolism General function prediction only 121606281 Common - acetyl-CoA carboxylase, biotin carboxyl carrier protein Pnap_3392 185 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 121605508 Common - Oligopeptidase A Pnap_2614 123 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 121605177 Nonpathogen - hypothetical protein Pnap_2277 1 None None None 121603181 Common - High potential iron-sulfur protein Pnap_0264 6 None None None 121605804 Common - type 4 fimbrial biogenesis protein PilY1 Pnap_2913 36 COG3419 PilY1, Tfp pilus assembly protein, tip-associated adhesin PilY1 Cell motility and secretion / Intracellular trafficking and secretion 121606994 Common - tRNA modification GTPase TrmE Pnap_4112 220 COG0486 ThdF, Predicted GTPase General function prediction only 121602973 Nonpathogen - hypothetical protein Pnap_0055 1 None None None 121604498 Common - SMP-30/Gluconolaconase/LRE domain protein Pnap_1592 75 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 121604098 Common - Cupin 4 family protein Pnap_1191 56 COG2850 COG2850, Uncharacterized conserved protein Function unknown 121606378 Common - glucose-1-phosphate thymidylyltransferase Pnap_3489 232 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 121604776 Common - hypothetical protein Pnap_1874 71 COG2976 COG2976, Uncharacterized protein conserved in bacteria Function unknown 121606482 Common - PGAP1 family protein Pnap_3594 17 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 121603270 Common - polysaccharide deacetylase Pnap_0355 71 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 121603231 Common - hypothetical protein Pnap_0316 5 None None None 121606455 Common - short-chain dehydrogenase/reductase SDR Pnap_3567 223 COG0623 FabI, Enoyl- acyl-carrier-protein 121604200 Common - transcriptional regulator, TetR family Pnap_1293 37 COG1309 AcrR, Transcriptional regulator Transcription 121605902 Common - acetylornithine and succinylornithine aminotransferases Pnap_3011 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 121605813 Common - MotA/TolQ/ExbB proton channel Pnap_2922 126 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 121603974 Common - transglutaminase, N-terminal domain protein Pnap_1065 79 COG4196 COG4196, Uncharacterized protein conserved in bacteria Function unknown 121604931 Common - Uncharacterized protein UPF0065 Pnap_2030 70 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121605370 Common - hypothetical protein Pnap_2473 4 None None None 121603470 Common - FMN reductase Pnap_0558 54 COG0431 COG0431, Predicted flavoprotein General function prediction only 121605187 Common - co-chaperone Hsc20 Pnap_2287 54 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 121605944 Common - hypothetical protein Pnap_3053 14 None None None 121606238 Common - Deoxyribodipyrimidine photo-lyase Pnap_3349 138 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 121604308 Common - uroporphyrin-III C-methyltransferase Pnap_1402 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 121606688 Common - NAD(P)(+) transhydrogenase (AB-specific) Pnap_3800 166 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 121605369 Common - transposase IS116/IS110/IS902 family protein Pnap_2472 92 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 121606419 Common - inner-membrane translocator Pnap_3530 149 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 121604686 Common - dihydrolipoamide dehydrogenase Pnap_1784 232 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 121605844 Common - ABC transporter related Pnap_2953 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 121604029 Common - Uncharacterized protein UPF0065 Pnap_1121 68 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121604974 Common - polar amino acid ABC transporter, inner membrane subunit Pnap_2073 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 121605845 Common - ABC transporter related Pnap_2954 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 121606842 Common - regulatory protein RecX Pnap_3955 59 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 121602967 Common - Aldehyde ferredoxin oxidoreductase Pnap_0049 58 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 121605866 Common - hypothetical protein Pnap_2975 8 None None None 121604851 Common - type IV pilus assembly PilZ Pnap_1950 33 COG3215 PilZ, Tfp pilus assembly protein PilZ Cell motility and secretion / Intracellular trafficking and secretion 121606164 Common - PHP C-terminal domain protein Pnap_3274 125 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 121603726 Common - non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family Pnap_0815 234 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 121603735 Common - hypothetical protein Pnap_0824 3 None None None 121603426 Common - putative threonine aldolase Pnap_0513 66 COG3616 COG3616, Predicted amino acid aldolase or racemase Amino acid transport and metabolism 121605752 Common - binding-protein-dependent transport systems inner membrane component Pnap_2860 207 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 121604709 Common - hypothetical protein Pnap_1807 8 None None None 121605696 Common - hypothetical protein Pnap_2802 17 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 121604178 Common - protein of unknown function DUF427 Pnap_1271 51 COG2343 COG2343, Uncharacterized protein conserved in bacteria Function unknown 121604671 Common - beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ Pnap_1769 187 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 121605967 Common - 3-oxoacyl-(acyl carrier protein) synthase III Pnap_3076 224 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 121606838 Common - Integral membrane protein TerC Pnap_3951 55 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 121603505 Common - putative transposase Pnap_0594 35 COG5659 COG5659, FOG: Transposase DNA replication, recombination, and repair 121604696 Common - hypothetical protein Pnap_1794 11 None None None 121605086 Common - Erythromycin esterase Pnap_2186 82 COG2312 COG2312, Erythromycin esterase homolog General function prediction only 121603084 Common - exodeoxyribonuclease III Xth Pnap_0167 188 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 121604415 Common - binding-protein-dependent transport systems inner membrane component Pnap_1509 68 COG4662 TupA, ABC-type tungstate transport system, periplasmic component Coenzyme metabolism 121606856 Common - hypothetical protein Pnap_3969 23 COG4309 COG4309, Uncharacterized conserved protein Function unknown 121604818 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Pnap_1916 224 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 121605119 Common - CreA family protein Pnap_2219 57 COG3045 CreA, Uncharacterized protein conserved in bacteria Function unknown 121604565 Common - transcriptional regulator, LysR family Pnap_1659 91 COG0583 LysR, Transcriptional regulator Transcription 121605278 Common - acetyl-CoA carboxylase, biotin carboxylase Pnap_2379 238 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 121604250 Common - geranylgeranyl reductase Pnap_1343 134 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 121603111 Common - VanZ family protein Pnap_0194 13 COG5652 COG5652, Predicted integral membrane protein Function unknown 121604940 Common - modD protein Pnap_2039 117 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 121605356 Common - inner-membrane translocator Pnap_2458 161 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 121603462 Common - inner-membrane translocator Pnap_0550 87 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 121604257 Nonpathogen - hypothetical protein Pnap_1350 2 None None None 121603193 Common - cyclic nucleotide-binding protein Pnap_0277 11 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 121604442 Common - integral membrane sensor signal transduction histidine kinase Pnap_1536 201 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121604297 Common - hypothetical protein Pnap_1391 30 COG5499 COG5499, Predicted transcription regulator containing HTH domain Transcription 121604582 Common - Lytic transglycosylase, catalytic Pnap_1677 124 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 121603253 Common - ribosomal protein L30 Pnap_0338 134 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 121603449 Common - transposase, IS4 family protein Pnap_0537 64 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 121603667 Common - general secretion pathway protein D Pnap_0756 142 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 121604934 Common - protein of unknown function DUF453 Pnap_2033 56 COG2828 COG2828, Uncharacterized protein conserved in bacteria Function unknown 121604396 Common - hypothetical protein Pnap_1490 36 COG3391 COG3391, Uncharacterized conserved protein Function unknown 121604318 Common - nitrate ABC transporter, ATPase subunits C and D Pnap_1412 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 121604847 Common - glycine cleavage T protein (aminomethyl transferase) Pnap_1946 111 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 121604708 Nonpathogen - transposase and inactivated derivative Pnap_1806 2 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 121605394 Nonpathogen - hypothetical protein Pnap_2498 1 None None None 121606751 Common - phosphoribosylaminoimidazole carboxylase, catalytic subunit Pnap_3863 226 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 121606463 Common - CheB methylesterase Pnap_3575 150 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 121604590 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Pnap_1685 159 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 121603258 Common - 30S ribosomal protein S11 Pnap_0343 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 121604196 Common - protein of unknown function DUF808 Pnap_1289 60 COG2354 COG2354, Uncharacterized protein conserved in bacteria Function unknown 121606866 Nonpathogen - hypothetical protein Pnap_3979 1 None None None 121606075 Common - glycosyl transferase, family 2 Pnap_3185 179 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 121603672 Common - methylation precursor Pnap_0761 6 COG4795 PulJ, Type II secretory pathway, component PulJ Intracellular trafficking and secretion 121604552 Common - hypothetical protein Pnap_1646 9 None None None 121603031 Common - ATP-dependent DNA helicase RecQ Pnap_0114 231 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 121606404 Common - hypothetical protein Pnap_3515 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 121604449 Common - sulfate ABC transporter, periplasmic sulfate-binding protein Pnap_1543 93 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 121604355 Common - amine oxidase Pnap_1449 69 COG2907 COG2907, Predicted NAD/FAD-binding protein General function prediction only 121606295 Common - TonB family protein Pnap_3406 32 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 121606629 Common - hypothetical protein Pnap_3741 8 None None None 121605418 Common - transposase IS3/IS911 family protein Pnap_2523 11 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 121604456 Common - transcriptional regulator, LysR family Pnap_1550 120 COG0583 LysR, Transcriptional regulator Transcription 121605101 Common - two component transcriptional regulator, winged helix family Pnap_2201 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 121606670 Common - cytochrome c oxidase, cbb3-type, subunit I Pnap_3782 141 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 121604402 Common - 3-mercaptopyruvate sulfurtransferase Pnap_1496 135 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 121605953 Common - putative transmembrane protein Pnap_3062 10 None None None 121603176 Common - LemA family protein Pnap_0259 131 COG1704 LemA, Uncharacterized conserved protein Function unknown 121603790 Common - hypothetical protein Pnap_0881 4 None None None 121606678 Common - SmpA/OmlA domain protein Pnap_3790 54 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 121606900 Common - 2-dehydropantoate 2-reductase Pnap_4016 135 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 121604404 Common - Rieske (2Fe-2S) domain protein Pnap_1498 81 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 121603229 Nonpathogen - hypothetical protein Pnap_0314 1 None None None 121605925 Common - succinate dehydrogenase, flavoprotein subunit Pnap_3034 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 121605411 Common - transcriptional regulator, TetR family Pnap_2515 74 COG1309 AcrR, Transcriptional regulator Transcription 121604585 Common - ribonuclease H Pnap_1680 179 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 121603220 Common - hypothetical protein Pnap_0305 13 None None None 121606395 Common - pyruvate carboxyltransferase Pnap_3506 201 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 121604281 Common - hypothetical protein Pnap_1374 43 COG4258 COG4258, Predicted exporter General function prediction only 121604207 Common - RND efflux system, outer membrane lipoprotein, NodT family Pnap_1300 111 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 121603163 Common - aminotransferase, class IV Pnap_0246 168 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 121605979 Common - protein of unknown function DUF513, hemX Pnap_3088 44 COG2959 HemX, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 121605805 Common - type IV pilin PilE Pnap_2914 58 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 121606763 Common - branched-chain amino acid transport Pnap_3875 7 COG4392 COG4392, Predicted membrane protein Function unknown 121603277 Common - primosomal protein N' Pnap_0362 208 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 121605938 Common - tryptophan synthase, alpha subunit Pnap_3047 217 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 121605170 Nonpathogen - hypothetical protein Pnap_2270 1 None None None 121606728 Common - peptidase M19, renal dipeptidase Pnap_3840 99 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 121603863 Common - malonate transporter MadL subunit Pnap_0954 11 None None None 121603152 Common - hypothetical protein Pnap_0235 7 None None None 121606306 Common - UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase Pnap_3417 208 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 121603309 Common - Creatininase Pnap_0394 88 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 121606684 Common - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase Pnap_3796 91 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 121606957 Common - dimethyladenosine transferase Pnap_4074 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 121603933 Common - transcriptional regulator, LysR family Pnap_1024 104 COG0583 LysR, Transcriptional regulator Transcription 121605003 Common - GCN5-related N-acetyltransferase Pnap_2102 19 COG3153 COG3153, Predicted acetyltransferase General function prediction only 121605125 Common - ATPase AAA-2 domain protein Pnap_2225 226 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 121605868 Common - major facilitator superfamily MFS_1 Pnap_2977 87 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 121605193 Common - hypothetical protein Pnap_2293 20 COG3133 SlyB, Outer membrane lipoprotein Cell envelope biogenesis, outer membrane 121604608 Common - signal transduction histidine kinase with CheB and CheR activity Pnap_1703 227 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 121605986 Common - protein of unknown function UPF0118 Pnap_3095 176 COG0628 PerM, Predicted permease General function prediction only 121603535 Common - Deoxyribonuclease I Pnap_0624 29 COG2356 EndA, Endonuclease I DNA replication, recombination, and repair 121603954 Common - hypothetical protein Pnap_1045 150 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 121606489 Common - osmosensitive K+ channel signal transduction histidine kinase Pnap_3601 219 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 121604418 Nonpathogen - hypothetical protein Pnap_1512 1 None None None 121603924 Common - transcriptional regulator, LysR family Pnap_1015 173 COG0583 LysR, Transcriptional regulator Transcription 121603690 Common - histidine triad (HIT) protein Pnap_0779 64 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 121604033 Nonpathogen - hypothetical protein Pnap_1125 2 None None None 121604913 Common - NusA antitermination factor Pnap_2012 216 COG0195 NusA, Transcription elongation factor Transcription 121605314 Common - TOBE domain protein Pnap_2415 35 COG3585 MopI, Molybdopterin-binding protein Coenzyme metabolism 121606392 Common - putative polyhydroxyalkanoic acid system protein Pnap_3503 11 None None None 121606146 Common - lipoprotein releasing system, transmembrane protein, LolC/E family Pnap_3256 180 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 121604445 Common - NADPH-dependent FMN reductase Pnap_1539 109 COG0431 COG0431, Predicted flavoprotein General function prediction only 121605454 Common - putative hydroxylase Pnap_2559 44 COG3128 PiuC, Uncharacterized iron-regulated protein Function unknown 121605302 Common - Antibiotic biosynthesis monooxygenase Pnap_2403 34 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 121605339 Common - Recombinase Pnap_2440 25 None None None 121604223 Common - cyclic nucleotide-binding domain (cNMP-BD) protein Pnap_1316 29 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 121605860 Common - RND efflux system, outer membrane lipoprotein, NodT family Pnap_2969 101 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 121604684 Common - pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase Pnap_1782 198 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 121604370 Common rplS 50S ribosomal protein L19 Pnap_1464 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 121604780 Common - GTP-binding protein, HSR1-related Pnap_1878 218 COG2262 HflX, GTPases General function prediction only 121605316 Common - binding-protein-dependent transport systems inner membrane component Pnap_2417 183 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 121604731 Common - protein of unknown function DUF1624 Pnap_1829 27 COG3503 COG3503, Predicted membrane protein Function unknown 121602922 Common - hypothetical protein Pnap_0004 3 None None None 121604781 Common - HflK protein Pnap_1879 204 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 121603144 Common - extracellular solute-binding protein, family 1 Pnap_0227 61 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 121604188 Common - major facilitator superfamily MFS_1 Pnap_1281 129 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 121606672 Common - heavy metal translocating P-type ATPase Pnap_3784 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 121603584 Common - Fimbrial assembly family protein Pnap_0673 38 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 121603486 Common - protein of unknown function DUF1501 Pnap_0574 6 COG4102 COG4102, Uncharacterized protein conserved in bacteria Function unknown 121606223 Common - phage integrase family protein Pnap_3334 100 COG0582 XerC, Integrase DNA replication, recombination, and repair 121604689 Common - NLP/P60 protein Pnap_1787 149 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 121603090 Common - cell shape determining protein, MreB/Mrl family Pnap_0173 225 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 121604374 Common - transcriptional coactivator/pterin dehydratase Pnap_1468 117 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 121604937 Common - transcriptional regulator, ModE family Pnap_2036 110 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 121605624 Common - Extracellular ligand-binding receptor Pnap_2730 120 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 121603850 Common - acetone carboxylase gamma subunit Pnap_0941 22 COG4647 AcxC, Acetone carboxylase, gamma subunit Secondary metabolites biosynthesis, transport, and catabolism 121605521 Common - ethanolamine ammonia-lyase small subunit Pnap_2627 54 COG4302 EutC, Ethanolamine ammonia-lyase, small subunit Amino acid transport and metabolism 121604639 Common - ribonuclease, Rne/Rng family Pnap_1735 184 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 121603421 Common - protein of unknown function UPF0054 Pnap_0508 145 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 121604577 Common recR recombination protein RecR Pnap_1672 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 121602937 Common - thiamine biosynthesis protein ThiC Pnap_0019 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 121604329 Common secG preprotein translocase subunit SecG Pnap_1423 23 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 121603812 Common - formamidopyrimidine-DNA glycosylase Pnap_0903 182 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 121603343 Common - Integrase, catalytic region Pnap_0429 151 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 121603248 Common - ribosomal protein S14 Pnap_0333 210 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 121604752 Nonpathogen - hypothetical protein Pnap_1850 1 None None None 121604527 Common - putative transmembrane protein Pnap_1621 27 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 121603104 Common - DSBA oxidoreductase Pnap_0187 44 COG3917 NahD, 2-hydroxychromene-2-carboxylate isomerase Secondary metabolites biosynthesis, transport, and catabolism 121606824 Nonpathogen - hypothetical protein Pnap_3936 1 None None None 121604764 Nonpathogen - protein of unknown function DUF465 Pnap_1862 2 COG5481 COG5481, Uncharacterized conserved small protein containing a coiled-coil domain Function unknown 121605039 Common - HpcH/HpaI aldolase Pnap_2139 105 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 121606534 Common secE preprotein translocase subunit SecE Pnap_3646 44 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 121604941 Common - molybdate ABC transporter, inner membrane subunit Pnap_2040 210 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 121606929 Common - PAS/PAC sensor signal transduction histidine kinase Pnap_4046 186 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 121604900 Common - hypothetical protein Pnap_1999 6 None None None 121606743 Common - hypothetical protein Pnap_3855 10 None None None 121603749 Common - Uncharacterized protein UPF0065 Pnap_0840 68 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121605908 Common - short-chain dehydrogenase/reductase SDR Pnap_3017 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 121604545 Nonpathogen - hypothetical protein Pnap_1639 1 None None None 121604484 Common - leucine rich repeat variant Pnap_1578 13 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 121603203 Common - lipoprotein, putative Pnap_0288 3 None None None 121605809 Common ribH riboflavin synthase subunit beta Pnap_2918 230 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 121605121 Nonpathogen - regulatory protein, MerR family Pnap_2221 9 None None None 121605682 Common - 3-demethylubiquinone-9 3-methyltransferase Pnap_2788 173 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 121603188 Common - protein of unknown function UPF0102 Pnap_0271 64 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 121605153 Common - peptidase S14, ClpP Pnap_2253 163 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 121603699 Common - UspA domain protein Pnap_0788 92 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 121603997 Common - proline iminopeptidase Pnap_1088 102 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 121607001 Common - DNA gyrase, B subunit Pnap_4119 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 121605424 Common - domain of unknown function DUF1738 Pnap_2529 48 COG4227 COG4227, Antirestriction protein DNA replication, recombination, and repair 121604468 Common - aromatic amino acid aminotransferase Pnap_1562 71 COG1448 TyrB, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 121606773 Common secD preprotein translocase subunit SecD Pnap_3885 201 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 121604506 Common - 2-hydroxy-3-oxopropionate reductase Pnap_1600 183 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 121604265 Common - 20S proteasome, A and B subunits Pnap_1358 54 COG3484 COG3484, Predicted proteasome-type protease Posttranslational modification, protein turnover, chaperones 121606869 Common - hypothetical protein Pnap_3983 41 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 121603844 Nonpathogen - hypothetical protein Pnap_0935 4 COG3462 COG3462, Predicted membrane protein Function unknown 121605200 Common - transport-associated Pnap_2300 45 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 121603941 Common - Methyltransferase type 11 Pnap_1032 63 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 121605533 Common - hypothetical protein Pnap_2639 2 None None None 121604044 Common - transposase, IS4 family protein Pnap_1136 21 None None None 121605853 Common - hypothetical protein Pnap_2962 103 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 121604826 Common - Biopolymer transport protein ExbD/TolR Pnap_1924 29 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 121604886 Common - phosphoglycolate phosphatase Pnap_1985 190 COG0546 Gph, Predicted phosphatases General function prediction only 121605295 Common - Na+/solute symporter Pnap_2396 128 COG4147 DhlC, Predicted symporter General function prediction only 121606096 Common - ABC transporter related Pnap_3206 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 121603562 Common - amidohydrolase Pnap_0651 167 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 121604132 Common - acyl-CoA dehydrogenase domain protein Pnap_1225 145 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 121603965 Nonpathogen - hypothetical protein Pnap_1056 1 None None None 121605552 Common - 3-oxoacid CoA-transferase, A subunit Pnap_2658 108 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 121605083 Common - acriflavin resistance protein Pnap_2183 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 121606231 Common - hypothetical protein Pnap_3342 9 COG5466 COG5466, Predicted small metal-binding protein Function unknown 121605493 Nonpathogen - hypothetical protein Pnap_2598 1 None None None 121603724 Common - protein kinase Pnap_0813 146 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 121603948 Common - basic membrane lipoprotein Pnap_1039 100 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 121604738 Common - protein of unknown function UPF0061 Pnap_1836 110 COG0397 COG0397, Uncharacterized conserved protein Function unknown 121605000 Common - hypothetical protein Pnap_2099 16 None None None 121603411 Common - protein of unknown function UPF0027 Pnap_0498 121 COG1690 RtcB, Uncharacterized conserved protein Function unknown 121606050 Common - PAS/PAC sensor signal transduction histidine kinase Pnap_3160 221 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 121603167 Common - F0F1 ATP synthase subunit C Pnap_0250 52 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 121603021 Nonpathogen - hypothetical protein Pnap_0104 1 None None None 121604627 Common - peptidase S11, D-alanyl-D-alanine carboxypeptidase 1 Pnap_1722 153 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 121603857 Common - malonate decarboxylase subunit delta Pnap_0948 20 None None None 121603302 Common - Radical SAM domain protein Pnap_0387 74 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 121603286 Nonpathogen - hypothetical protein Pnap_0371 1 None None None 121605601 Common - putative FAD-binding dehydrogenase Pnap_2707 53 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 121605764 Common - Malonyl-CoA decarboxylase Pnap_2873 29 None None None 121604617 Common - diacylglycerol kinase Pnap_1712 87 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 121604703 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pnap_1801 21 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 121604472 Common - iron-sulfur cluster assembly protein IscA Pnap_1566 163 COG0316 IscA, Uncharacterized conserved protein Function unknown 121605326 Common - nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein Pnap_2427 122 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 121603830 Common - multi-sensor signal transduction histidine kinase Pnap_0921 159 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 121604126 Common - ATPase associated with various cellular activities, AAA_3 Pnap_1219 174 COG0714 COG0714, MoxR-like ATPases General function prediction only 121603703 Common - putative transcriptional regulator, Crp/Fnr family Pnap_0792 147 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 121605713 Nonpathogen - hypothetical protein Pnap_2819 1 None None None 121606467 Common - YceI family protein Pnap_3579 91 COG2353 COG2353, Uncharacterized conserved protein Function unknown 121603362 Common - protein of unknown function DUF45 Pnap_0448 136 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 121604026 Common - fumarylacetoacetase Pnap_1118 50 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 121605321 Common - sulfate ABC transporter, periplasmic sulfate-binding protein Pnap_2422 89 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 121603384 Common - acyl-CoA synthetase Pnap_0470 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 121603266 Nonpathogen - hypothetical protein Pnap_0351 2 None None None 121603065 Common - hypothetical protein Pnap_0148 26 COG4391 COG4391, Uncharacterized protein conserved in bacteria Function unknown 121605612 Common - 5-carboxymethyl-2-hydroxymuconate isomerase Pnap_2718 31 COG3232 HpaF, 5-carboxymethyl-2-hydroxymuconate isomerase Amino acid transport and metabolism 121605415 Common - ABC-1 domain protein Pnap_2519 184 COG0661 AarF, Predicted unusual protein kinase General function prediction only 121604053 Common - putative ferric uptake regulator, Fur family Pnap_1145 8 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 121604907 Common - enoyl-CoA hydratase Pnap_2006 135 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 121603131 Common - GCN5-related N-acetyltransferase Pnap_0214 43 COG0456 RimI, Acetyltransferases General function prediction only 121604998 Common - hypothetical protein Pnap_2097 7 None None None 121606133 Common - TatD-related deoxyribonuclease Pnap_3243 225 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 121604100 Nonpathogen - hypothetical protein Pnap_1193 1 None None None 121606874 Common - short-chain dehydrogenase/reductase SDR Pnap_3988 216 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 121603525 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pnap_0614 20 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 121606020 Common - UDP-glucose/GDP-mannose dehydrogenase Pnap_3130 206 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 121603814 Common - A/G-specific adenine glycosylase Pnap_0905 227 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 121604149 Common - UbiA prenyltransferase Pnap_1242 101 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 121606582 Common - glucose-6-phosphate 1-dehydrogenase Pnap_3694 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 121606109 Common prfC peptide chain release factor 3 Pnap_3219 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 121604648 Common - Insertion element protein Pnap_1746 18 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 121606727 Common - conserved hypothetical protein, possibly involved in regulation of phenolics degradation Pnap_3839 21 COG4313 COG4313, Protein involved in meta-pathway of phenol degradation Energy production and conversion 121606478 Nonpathogen - hypothetical protein Pnap_3590 1 None None None 121603075 Nonpathogen - hypothetical protein Pnap_0158 1 None None None 121604993 Common - glycerophosphoryl diester phosphodiesterase Pnap_2092 114 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 121604302 Common - transposase IS116/IS110/IS902 family protein Pnap_1396 75 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 121605249 Common - Ankyrin Pnap_2350 90 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 121605736 Common - glutaredoxin Pnap_2843 66 None None None 121605234 Common - F0F1 ATP synthase subunit epsilon Pnap_2335 20 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 121603889 Nonpathogen - hypothetical protein Pnap_0980 2 None None None 121604962 Common - glycosyl transferase, family 51 Pnap_2061 200 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 121605783 Common - HhH-GPD family protein Pnap_2892 101 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 121606006 Common - sugar transferase Pnap_3116 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 121604601 Common - Uncharacterized protein UPF0065 Pnap_1696 75 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121604676 Common - carbamoyl phosphate synthase small subunit Pnap_1774 233 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 121604237 Common - Invasion gene expression up-regulator, SirB Pnap_1330 38 COG3094 COG3094, Uncharacterized protein conserved in bacteria Function unknown 121606643 Common - ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent Pnap_3755 221 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 121606818 Nonpathogen - hypothetical protein Pnap_3930 1 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 121605750 Common - Insertion element protein Pnap_2858 18 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 121606301 Common - cell division protein FtsZ Pnap_3412 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 121606574 Common - two component transcriptional regulator, winged helix family Pnap_3686 215 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 121603318 Common - putative transcriptional regulator, GntR family Pnap_0403 213 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 121606215 Common - hypothetical protein Pnap_3326 2 None None None 121606055 Common - alpha/beta hydrolase fold Pnap_3165 104 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 121605035 Common - Alcohol dehydrogenase, zinc-binding domain protein Pnap_2134 209 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 121603654 Common - protein of unknown function DUF21 Pnap_0743 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 121606916 Common - 8-amino-7-oxononanoate synthase Pnap_4032 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 121603401 Common - excinuclease ABC, A subunit Pnap_0488 236 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 121606308 Common - UDP-N-acetylmuramoylalanine--D-glutamate ligase Pnap_3419 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 121604713 Common - twitching motility protein Pnap_1811 165 COG5008 PilU, Tfp pilus assembly protein, ATPase PilU Cell motility and secretion / Intracellular trafficking and secretion 121603004 Nonpathogen - hypothetical protein Pnap_0087 2 None None None 121603823 Common - hypothetical protein Pnap_0914 7 None None None 121604185 Common - transposase, IS605 OrfB family Pnap_1278 74 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 121606903 Common - putative oxidoreductase Pnap_4019 186 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 121606153 Common - Exonuclease, RNase T and DNA polymerase III Pnap_3263 59 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 121604002 Common - O-succinylhomoserine sulfhydrylase Pnap_1093 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 121606590 Common - Sporulation domain protein Pnap_3702 23 COG3087 FtsN, Cell division protein Cell division and chromosome partitioning 121604226 Common - OmpA/MotB domain protein Pnap_1319 135 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 121604176 Common - coproporphyrinogen III oxidase Pnap_1269 203 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 121604892 Common - phage integrase family protein Pnap_1991 35 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 121603014 Common - multi-sensor signal transduction histidine kinase Pnap_0097 219 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 121603368 Common - uncharacterized domain 1 Pnap_0454 66 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 121603668 Common - putative general secretory pathway N transmembrane protein Pnap_0757 10 None None None 121604836 Common - ATP-dependent Clp protease, ATP-binding subunit clpA Pnap_1934 217 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 121604795 Nonpathogen - hypothetical protein Pnap_1893 1 None None None 121604643 Common - ISXo7 transposase Pnap_1739 47 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 121604970 Common - Mannitol dehydrogenase, C-terminal domain Pnap_2069 83 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 121604143 Common - protein of unknown function DUF112, transmembrane Pnap_1236 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 121603766 Common - surface antigen (D15) Pnap_0857 124 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 121605718 Common - beta-lactamase domain protein Pnap_2824 196 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 121603436 Common - extracellular solute-binding protein, family 1 Pnap_0523 64 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 121603756 Common - globin Pnap_0847 64 COG2346 COG2346, Truncated hemoglobins General function prediction only 121604061 Common - protein of unknown function DUF214 Pnap_1153 46 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 121603819 Common ntpA dATP pyrophosphohydrolase Pnap_0910 37 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 121604897 Common - Muramoyltetrapeptide carboxypeptidase Pnap_1996 77 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 121606634 Common - multi-sensor signal transduction histidine kinase Pnap_3746 204 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 121603612 Common - imidazoleglycerol phosphate synthase, cyclase subunit Pnap_0701 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 121605584 Common - secreted hydrolase-like protein Pnap_2690 28 COG5621 COG5621, Predicted secreted hydrolase General function prediction only 121604089 Common - hypothetical protein Pnap_1181 2 None None None 121606551 Common - sodium/hydrogen exchanger Pnap_3663 16 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 121605364 Common - IstB domain protein ATP-binding protein Pnap_2467 93 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 121605772 Common - hypothetical protein Pnap_2881 55 COG2862 COG2862, Predicted membrane protein Function unknown 121605619 Common - Rieske (2Fe-2S) domain protein Pnap_2725 76 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 121606260 Common - 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Pnap_3371 151 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 121603333 Common - transposase, IS4 family Pnap_0419 25 None None None 121606151 Common - hypothetical protein Pnap_3261 6 None None None 121603880 Common - urease accessory protein UreG Pnap_0971 143 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 121606611 Nonpathogen - hypothetical protein Pnap_3723 2 None None None 121606950 Common - diaminopropionate ammonia-lyase Pnap_4067 64 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 121604815 Common - putative transcriptional regulator, Crp/Fnr family Pnap_1913 101 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 121603530 Common - putative flavoprotein involved in K+ transport Pnap_0619 61 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 121605570 Common - Chalcone and stilbene synthases domain protein Pnap_2676 134 COG3424 BcsA, Predicted naringenin-chalcone synthase Secondary metabolites biosynthesis, transport, and catabolism 121606254 Common - MOSC domain protein beta barrel domain protein Pnap_3365 47 COG3217 COG3217, Uncharacterized Fe-S protein General function prediction only 121605565 Common - two component transcriptional regulator, winged helix family Pnap_2671 218 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 121604389 Common - putative transcriptional regulator Pnap_1483 33 COG1510 COG1510, Predicted transcriptional regulators Transcription 121604666 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase Pnap_1764 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 121603714 Common - ABC transporter related Pnap_0803 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 121606243 Common - response regulator receiver protein Pnap_3354 221 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 121604436 Common - protein of unknown function DUF1696 Pnap_1530 29 None None None 121604969 Common - Altronate dehydratase Pnap_2068 73 COG2721 UxaA, Altronate dehydratase Carbohydrate transport and metabolism 121606043 Common - type II secretion system protein E Pnap_3153 218 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 121604922 Common - protein of unknown function DUF107 Pnap_2021 12 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 121603053 Common - Uncharacterized protein UPF0065 Pnap_0136 73 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121603311 Common - Phosphoglycerate mutase Pnap_0396 26 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 121603370 Common - Carbonate dehydratase Pnap_0456 147 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 121604249 Common - peptidase M23B Pnap_1342 129 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 121603118 Common - elongation factor Tu Pnap_0201 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 121606347 Common - extracellular solute-binding protein, family 3 Pnap_3458 139 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 121604699 Nonpathogen - hypothetical protein Pnap_1797 1 None None None 121605581 Common - alpha/beta hydrolase fold Pnap_2687 110 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 121604593 Common mobA molybdopterin-guanine dinucleotide biosynthesis protein A Pnap_1688 102 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 121603641 Common - coenzyme PQQ synthesis D Pnap_0730 14 None None None 121603783 Common - RNA methyltransferase, TrmH family, group 2 Pnap_0874 157 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 121604210 Common - hypothetical protein Pnap_1303 34 COG3812 COG3812, Uncharacterized protein conserved in bacteria Function unknown 121604773 Common - hypothetical protein Pnap_1871 22 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 121605885 Common - phosphoribosylformylglycinamidine cyclo-ligase Pnap_2994 226 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 121603648 Common - extracellular solute-binding protein, family 3 Pnap_0737 13 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 121605022 Common - alpha/beta hydrolase fold Pnap_2121 110 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 121603918 Nonpathogen - hypothetical protein Pnap_1009 1 None None None 121606081 Common - NAD-dependent epimerase/dehydratase Pnap_3191 215 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 121606026 Nonpathogen - hypothetical protein Pnap_3136 1 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 121605518 Common - helix-turn-helix- domain containing protein, AraC type Pnap_2624 78 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 121602954 Common - biotin carboxylation domain protein Pnap_0036 230 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 121606351 Nonpathogen - hypothetical protein Pnap_3462 3 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 121605757 Common - peptidase C26 Pnap_2865 108 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 121603772 Common - hypothetical protein Pnap_0863 6 None None None 121603195 Common - transposase, IS605 OrfB family Pnap_0279 73 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 121603665 Common - general secretion pathway protein F Pnap_0754 142 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 121602988 Common - ATP--cobalamin adenosyltransferase Pnap_0070 126 COG2096 COG2096, Uncharacterized conserved protein Function unknown 121604491 Common - DegT/DnrJ/EryC1/StrS aminotransferase Pnap_1585 195 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 121605830 Common - Redoxin domain protein Pnap_2939 164 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 121603473 Common - amidohydrolase 2 Pnap_0561 30 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 121605484 Common - arsenical-resistance protein Pnap_2589 127 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 121603430 Common - dihydroneopterin aldolase Pnap_0517 19 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 121606758 Common - histidine kinase Pnap_3870 70 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121604865 Common - hydrogenase expression/synthesis, HypA Pnap_1964 86 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 121605054 Common - hypothetical protein Pnap_2154 14 COG5446 COG5446, Predicted integral membrane protein Function unknown 121604771 Common - radical SAM enzyme, Cfr family Pnap_1869 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 121606465 Common - Extracellular ligand-binding receptor Pnap_3577 148 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 121604244 Common - Antibiotic biosynthesis monooxygenase Pnap_1337 16 COG3224 COG3224, Uncharacterized protein conserved in bacteria Function unknown 121603873 Common - hypothetical protein Pnap_0964 34 COG4643 COG4643, Uncharacterized protein conserved in bacteria Function unknown 121604009 Common - methylated-DNA--protein-cysteine methyltransferase Pnap_1100 219 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 121605774 Common - hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha subunit Pnap_2883 148 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 121605742 Common pheT phenylalanyl-tRNA synthetase subunit beta Pnap_2849 248 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 121605738 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Pnap_2845 31 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 121606884 Nonpathogen - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Pnap_4000 13 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 121605211 Common - serine O-acetyltransferase Pnap_2311 203 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 121604000 Common - Colicin V production protein Pnap_1091 66 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 121605091 Nonpathogen - regulatory protein, ArsR Pnap_2191 1 COG1846 MarR, Transcriptional regulators Transcription 121606920 Common - transcriptional regulator, TetR family Pnap_4037 38 COG1309 AcrR, Transcriptional regulator Transcription 121606890 Nonpathogen - hypothetical protein Pnap_4006 2 None None None 121605380 Common - aromatic-ring-hydroxylating dioxygenase, beta subunit Pnap_2484 16 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 121603574 Common - GTP-binding protein, HSR1-related Pnap_0663 176 COG0218 COG0218, Predicted GTPase General function prediction only 121603150 Common - UspA domain protein Pnap_0233 53 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 121606116 Common - protein of unknown function UPF0187 Pnap_3226 56 COG3781 COG3781, Predicted membrane protein Function unknown 121606783 Common - multi-sensor signal transduction histidine kinase Pnap_3895 217 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 121605281 Common - arginine/ornithine transport system ATPase Pnap_2382 100 COG1703 ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family Amino acid transport and metabolism 121605143 Nonpathogen - hypothetical protein Pnap_2243 1 None None None 121603631 Common - Uncharacterized protein UPF0065 Pnap_0720 73 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121606753 Common - hypothetical protein Pnap_3865 29 COG4321 COG4321, Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis General function prediction only 121606737 Common - N-formylglutamate amidohydrolase Pnap_3849 30 COG3931 COG3931, Predicted N-formylglutamate amidohydrolase Amino acid transport and metabolism 121605010 Common benD 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase Pnap_2109 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 121604632 Common - protein of unknown function DUF853, NPT hydrolase putative Pnap_1727 76 COG0433 COG0433, Predicted ATPase General function prediction only 121605283 Common - transcriptional regulator, GntR family Pnap_2384 135 COG1802 GntR, Transcriptional regulators Transcription 121603225 Common - hypothetical protein Pnap_0310 3 None None None 121603197 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) Pnap_0281 192 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 121603299 Common - hypothetical protein Pnap_0384 16 None None None 121605793 Common - N6 adenine-specific DNA methyltransferase protein, N12 class Pnap_2902 51 COG1002 COG1002, Type II restriction enzyme, methylase subunits Defense mechanisms 121603044 Common - poly (3-hydroxybutyrate) depolymerase Pnap_0127 10 COG3509 LpqC, Poly(3-hydroxybutyrate) depolymerase Secondary metabolites biosynthesis, transport, and catabolism 121603235 Common - queuine tRNA-ribosyltransferase Pnap_0320 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 121604485 Common - NifZ family protein Pnap_1579 26 None None None 121603063 Common - Spore coat U domain protein Pnap_0146 5 COG5430 COG5430, Uncharacterized secreted protein Function unknown 121605182 Nonpathogen - hypothetical protein Pnap_2282 1 None None None 121606361 Common - L-lactate transport Pnap_3472 104 COG1620 LldP, L-lactate permease Energy production and conversion 121604428 Common - putative monovalent cation/H+ antiporter subunit D Pnap_1522 207 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 121605113 Common - transcriptional regulator, Fis family Pnap_2213 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 121604190 Common - putative cytochrome c Pnap_1283 59 COG2863 COG2863, Cytochrome c553 Energy production and conversion 121603159 Common - lipoyl synthase Pnap_0242 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 121604596 Common - aldehyde dehydrogenase Pnap_1691 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 121605465 Common - Biopolymer transport protein ExbD/TolR Pnap_2570 135 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 121606177 Common - acetate permease Pnap_3287 147 COG4147 DhlC, Predicted symporter General function prediction only 121604423 Common - 5-oxoprolinase (ATP-hydrolyzing) Pnap_1517 118 COG0146 HyuB, N-methylhydantoinase B/acetone carboxylase, alpha subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 121605384 Common - Rieske (2Fe-2S) domain protein Pnap_2488 81 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 121605184 Common - DNA polymerase III, epsilon subunit Pnap_2284 184 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 121605898 Common - Pyrrolo-quinoline quinone Pnap_3007 94 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 121606597 Common - ABC transporter related Pnap_3709 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 121605516 Common - hypothetical protein Pnap_2622 5 None None None 121606988 Common - protein of unknown function DUF1239 Pnap_4106 15 COG3117 COG3117, Uncharacterized protein conserved in bacteria Function unknown 121604135 Common - sulfatase Pnap_1228 61 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 121602959 Common - aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein Pnap_0041 128 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 121606283 Common - hypothetical protein Pnap_3394 21 None None None 121605501 Common - ROK family protein Pnap_2607 120 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 121602946 Common - Vault protein inter-alpha-trypsin domain protein Pnap_0028 35 COG2304 COG2304, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 121604340 Common - NADH-ubiquinone oxidoreductase, chain 4L Pnap_1434 160 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 121605021 Common - transcriptional regulator, LysR family Pnap_2120 188 COG0583 LysR, Transcriptional regulator Transcription 121605981 Common - porphobilinogen deaminase Pnap_3090 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 121603551 Common - Phosphoglycerate mutase Pnap_0640 42 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 121605258 Common - protein of unknown function DUF692 Pnap_2359 62 COG3220 COG3220, Uncharacterized protein conserved in bacteria Function unknown 121603291 Common - cytochrome c biogenesis protein, transmembrane region Pnap_0376 75 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 121603720 Common - (p)ppGpp synthetase I, SpoT/RelA Pnap_0809 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 121605650 Common - polyhydroxyalkanoate depolymerase, intracellular Pnap_2756 44 COG4553 DepA, Poly-beta-hydroxyalkanoate depolymerase Lipid metabolism 121604721 Common - PII uridylyl-transferase Pnap_1819 123 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 121604212 Common - anaerobic nitric oxide reductase transcription regulator Pnap_1305 167 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 121605189 Common - scaffold protein Pnap_2289 144 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 121604235 Common - putative nitric oxide reductase (subunit B) transmembrane protein Pnap_1328 82 COG3256 NorB, Nitric oxide reductase large subunit Inorganic ion transport and metabolism 121605837 Common - hypothetical protein Pnap_2946 7 None None None 121604313 Common - nitrite reductase (NAD(P)H), large subunit Pnap_1407 220 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 121603803 Common - putative methyltransferase Pnap_0894 203 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 121606963 Common - UbiC transcription regulator-associated domain protein Pnap_4080 80 COG2188 PhnF, Transcriptional regulators Transcription 121605598 Common - putative FAD-binding dehydrogenase Pnap_2704 59 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 121606484 Common - putative transmembrane protein Pnap_3596 7 COG5488 COG5488, Integral membrane protein Function unknown 121604473 Common - iron-sulfur cluster assembly accessory protein Pnap_1567 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 121603719 Common - transcription elongation factor GreB Pnap_0808 190 COG0782 GreA, Transcription elongation factor Transcription 121604357 Common - Cyclopropane-fatty-acyl-phospholipid synthase Pnap_1451 147 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 121603989 Common - nucleotide-binding protein Pnap_1080 107 COG1666 COG1666, Uncharacterized protein conserved in bacteria Function unknown 121604400 Common - hypothetical protein Pnap_1494 11 None None None 121606506 Common - transcriptional regulator, MarR family Pnap_3618 78 COG1846 MarR, Transcriptional regulators Transcription 121605939 Common - acetyl-CoA carboxylase, carboxyl transferase, beta subunit Pnap_3048 212 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 121603375 Common - aminotransferase, class V Pnap_0461 112 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 121603455 Common - cysteine desulfurases, SufS subfamily Pnap_0543 240 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 121604988 Nonpathogen - hypothetical protein Pnap_2087 4 None None None 121606701 Common - Uncharacterized protein UPF0065 Pnap_3813 59 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 121606417 Common - ABC transporter related Pnap_3528 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 121605698 Common - acetyl-CoA acetyltransferase Pnap_2804 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 121606943 Common - glutaredoxin Pnap_4060 24 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 121605268 Nonpathogen - hypothetical protein Pnap_2369 2 COG4467 COG4467, Uncharacterized protein conserved in bacteria Function unknown 121605727 Common - OsmC family protein Pnap_2833 5 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 121603168 Common - ATP synthase F0, B subunit Pnap_0251 110 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 121605218 Common - tetratricopeptide TPR_2 Pnap_2318 8 None None None 121606911 Common - Calcium/calmodulin dependent protein kinase II, association-domain protein Pnap_4027 15 COG4875 COG4875, Uncharacterized protein conserved in bacteria with a cystatin-like fold Function unknown 121604542 Common - translation elongation factor G Pnap_1636 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 121604534 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Pnap_1628 206 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 121603214 Common - Extracellular ligand-binding receptor Pnap_0299 94 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 121604750 Common - putative glutathione S-transferase-related protein Pnap_1848 27 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 121603976 Common - fructose-1,6-bisphosphatase Pnap_1067 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 121606001 Common - alpha-2-macroglobulin domain protein Pnap_3110 63 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 121605761 Common - malonyl-CoA synthase Pnap_2870 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 121604347 Common - Glu/Leu/Phe/Val dehydrogenase, C terminal Pnap_1441 180 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 121603558 Common - outer membrane protein (porin)-like protein Pnap_0647 17 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 121605856 Common - amine oxidase Pnap_2965 35 COG2907 COG2907, Predicted NAD/FAD-binding protein General function prediction only 121603127 Common rplP 50S ribosomal protein L16 Pnap_0210 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 121604059 Common - protein of unknown function DUF47 Pnap_1151 74 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 121606834 Common - Fimbrial protein pilin Pnap_3946 6 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 121603408 Common - cytochrome bd ubiquinol oxidase, subunit II Pnap_0495 147 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 121606798 Common - rfaE bifunctional protein Pnap_3910 130 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 121606320 Common - putative transcriptional regulator, GntR family Pnap_3431 201 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 121606836 Common - FHA domain containing protein Pnap_3949 66 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 121603503 Nonpathogen - hypothetical protein Pnap_0591 3 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 121603582 Common - penicillin-binding protein, 1A family Pnap_0671 200 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 121603741 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Pnap_0832 72 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 121606800 Common - glutathione peroxidase Pnap_3912 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 121604327 Common - Alcohol dehydrogenase, zinc-binding domain protein Pnap_1421 198 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 121606412 Common - two component transcriptional regulator, LuxR family Pnap_3523 200 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 121602974 Common - GCN5-related N-acetyltransferase Pnap_0056 218 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 121603005 Nonpathogen - hypothetical protein Pnap_0088 6 COG0759 COG0759, Uncharacterized conserved protein Function unknown 121603842 Common - pantoate--beta-alanine ligase Pnap_0933 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 121606329 Common - Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein Pnap_3440 86 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 121604759 Common - dihydrolipoamide acetyltransferase Pnap_1857 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 121603590 Common - 3-dehydroquinate synthase Pnap_0679 212 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 121606622 Common - glutamine amidotransferase, class-II Pnap_3734 77 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 121604872 Common - hydrogenase expression/formation protein Pnap_1971 77 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 121605923 Common - succinate dehydrogenase, cytochrome b subunit Pnap_3032 57 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 121603826 Nonpathogen - hypothetical protein Pnap_0917 1 None None None 121604155 Common - amidohydrolase Pnap_1248 171 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 121605073 Common - transcriptional regulator CysB-like protein Pnap_2173 174 COG0583 LysR, Transcriptional regulator Transcription 121603178 Common - hydrolase of the alpha/beta-hydrolase fold-like protein Pnap_0261 67 COG0429 COG0429, Predicted hydrolase of the alpha/beta-hydrolase fold General function prediction only 121606562 Common - hypothetical protein Pnap_3674 4 None None None 121605932 Common - 3-isopropylmalate dehydrogenase Pnap_3041 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 121603670 Common - hypothetical protein Pnap_0759 7 COG3297 PulL, Type II secretory pathway, component PulL Intracellular trafficking and secretion 121604394 Common - ABC transporter related Pnap_1488 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 121604813 Common - acyl-CoA dehydrogenase domain protein Pnap_1911 144 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 121603082 Common - putative transposase Pnap_0165 35 COG5659 COG5659, FOG: Transposase DNA replication, recombination, and repair 121604725 Common - PilT protein domain protein Pnap_1823 62 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 121604845 Common - iron-containing alcohol dehydrogenase Pnap_1943 173 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 121603243 Common - glycerol kinase Pnap_0328 181 COG0554 GlpK, Glycerol kinase Energy production and conversion 121603800 Common - signal recognition particle-docking protein FtsY Pnap_0891 246 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 121604879 Common - Ribulose-bisphosphate carboxylase Pnap_1978 66 COG1850 RbcL, Ribulose 1,5-bisphosphate carboxylase, large subunit Carbohydrate transport and metabolism 121606536 Common - uracil-DNA glycosylase Pnap_3648 128 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 121604587 Common - acriflavin resistance protein Pnap_1682 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 121605068 Common - DNA polymerase III subunit chi Pnap_2168 48 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 121605164 Common - hypothetical protein Pnap_2264 6 COG4197 COG4197, Uncharacterized protein conserved in bacteria, prophage-related Function unknown 121604020 Common - protein of unknown function DUF1486 Pnap_1111 15 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 121604284 Common - putative transmembrane protein Pnap_1378 10 COG4648 COG4648, Predicted membrane protein Function unknown 121606784 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Pnap_3896 194 COG0388 COG0388, Predicted amidohydrolase General function prediction only 121604710 Common - ABC transporter related Pnap_1808 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 121603968 Common - UDP-glucose 4-epimerase Pnap_1059 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 121604763 Common - protein phosphatase 2C domain protein Pnap_1861 117 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 121604336 Common - NADH dehydrogenase subunit G Pnap_1430 197 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 121604976 Common - GntR domain protein Pnap_2075 153 COG2186 FadR, Transcriptional regulators Transcription 121605672 Common - signal transduction histidine kinase, nitrogen specific, NtrB Pnap_2778 217 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 121605766 Common - multi-sensor hybrid histidine kinase Pnap_2875 223 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 121605135 Common - PhoH family protein Pnap_2235 191 COG1875 COG1875, Predicted ATPase related to phosphate starvation-inducible protein PhoH Signal transduction mechanisms 121606793 Common - prevent-host-death family protein Pnap_3905 44 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 121603161 Common - yecA family protein Pnap_0244 6 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 121605481 Common - arsenate reductase Pnap_2586 107 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 121605955 Common - GTP-binding protein LepA Pnap_3064 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 121606545 Common - Ketopantoate reductase ApbA/PanE, C-terminal domain protein Pnap_3657 76 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 121604385 Common - integral membrane protein-like protein Pnap_1479 25 COG5528 COG5528, Predicted integral membrane protein Function unknown 121603222 Common - helix-turn-helix domain protein Pnap_0307 16 None None None 121605191 Common - transcriptional regulator, BadM/Rrf2 family Pnap_2291 172 COG1959 COG1959, Predicted transcriptional regulator Transcription 121605531 Common - FMN-binding domain protein Pnap_2637 42 COG3901 NosR, Regulator of nitric oxide reductase transcription Transcription 121606978 Common - transposase, IS4 family protein Pnap_4096 33 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 121605085 Common - dienelactone hydrolase Pnap_2185 28 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 121603275 Common - hypothetical protein Pnap_0360 30 COG0628 PerM, Predicted permease General function prediction only 121606421 Common - porin, Gram-negative type Pnap_3532 26 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 121603900 Common - band 7 protein Pnap_0991 202 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 121605816 Common - DNA polymerase III, alpha subunit Pnap_2925 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 121606374 Common - glycosyl transferase, family 2 Pnap_3485 63 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 121606297 Common - monofunctional biosynthetic peptidoglycan transglycosylase Pnap_3408 199 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 121602961 Common - TRAP dicarboxylate transporter, DctP subunit Pnap_0043 101 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 121605740 Common - putative transcriptional regulator, MerR family Pnap_2847 94 COG0789 SoxR, Predicted transcriptional regulators Transcription 121604171 Nonpathogen - hypothetical protein Pnap_1264 1 None None None 121604074 Common - GAF modulated sigma54 specific transcriptional regulator, Fis family Pnap_1166 191 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 121606686 Common - NAD(P) transhydrogenase, beta subunit Pnap_3798 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 121603712 Common - inner-membrane translocator Pnap_0801 110 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 121603797 Common - electron transport protein SCO1/SenC Pnap_0888 99 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 121606012 Common - LPS biosynthesis protein WbpG Pnap_3122 23 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 121606090 Common apaH diadenosine tetraphosphatase Pnap_3200 76 COG0639 ApaH, Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Signal transduction mechanisms 121603464 Common - hypothetical protein Pnap_0552 29 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 121605802 Common - Tfp pilus assembly protein PilW-like protein Pnap_2911 10 COG4966 PilW, Tfp pilus assembly protein PilW Cell motility and secretion / Intracellular trafficking and secretion 121603423 Common ruvA Holliday junction DNA helicase motor protein Pnap_0510 209 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 121606102 Common - putative transcriptional regulator, Crp/Fnr family Pnap_3212 158 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 121606373 Common - NAD-dependent epimerase/dehydratase Pnap_3484 173 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 121605108 Common - twin-arginine translocation pathway signal Pnap_2208 16 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 121603418 Common - peptidase M23B Pnap_0505 192 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 121604567 Common - protein of unknown function DUF159 Pnap_1661 88 COG2135 COG2135, Uncharacterized conserved protein Function unknown 121606696 Common - hypothetical protein Pnap_3808 31 COG3777 COG3777, Uncharacterized conserved protein Function unknown 121603832 Common - response regulator receiver protein Pnap_0923 18 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 121606457 Common - acetate kinase Pnap_3569 161 COG0282 ackA, Acetate kinase Energy production and conversion 121606314 Common - S-adenosyl-methyltransferase MraW Pnap_3425 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 121603472 Common - Alkanesulfonate monooxygenase Pnap_0560 89 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 121603493 Nonpathogen - hypothetical protein Pnap_0581 7 None None None 121606996 Common - protein of unknown function DUF37 Pnap_4114 182 COG0759 COG0759, Uncharacterized conserved protein Function unknown 121605330 Common - sulfate adenylyltransferase, large subunit Pnap_2431 247 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 121605972 Common - putative transmembrane protein Pnap_3081 197 COG0313 COG0313, Predicted methyltransferases General function prediction only 121604017 Common - Phosphomannomutase Pnap_1108 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 121605960 Common - hypothetical protein Pnap_3069 4 None None None 121603233 Common - GtrA family protein Pnap_0318 19 COG2246 COG2246, Predicted membrane protein Function unknown 121603993 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Pnap_1084 131 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 121605222 Common - protein of unknown function DUF269 Pnap_2322 25 None None None 121604510 Common - RNA polymerase, sigma 70 subunit, RpoD family Pnap_1604 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 121605546 Common - hypothetical protein Pnap_2652 44 COG4643 COG4643, Uncharacterized protein conserved in bacteria Function unknown 121603647 Common - cytochrome c-type protein Pnap_0736 13 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 121604858 Common - formyl transferase domain protein Pnap_1957 22 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 121605842 Common - inner-membrane translocator Pnap_2951 139 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 121604417 Common - hypothetical protein Pnap_1511 62 COG2998 TupB, ABC-type tungstate transport system, permease component Coenzyme metabolism 121603774 Common - 3-oxoacid CoA-transferase, A subunit Pnap_0865 90 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 121605407 Common - conjugation TrbI family protein Pnap_2511 58 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 121606757 Common - fructose-1,6-bisphosphate aldolase Pnap_3869 176 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 121604554 Common - regulatory proteins, IclR Pnap_1648 118 COG1414 IclR, Transcriptional regulator Transcription 121605049 Common - cob(II)yrinic acid a,c-diamide reductase Pnap_2149 87 COG0778 NfnB, Nitroreductase Energy production and conversion 121603251 Common - ribosomal protein L18P/L5E Pnap_0336 206 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 121604742 Common - ABC transporter related Pnap_1840 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 121606448 Nonpathogen - zinc finger, RanBP2-type Pnap_3560 4 None None None 121606527 Common - DNA-directed RNA polymerase subunit beta' Pnap_3639 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 121604035 Common - Rhodanese domain protein Pnap_1127 64 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 121605112 Common - polyphosphate kinase Pnap_2212 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 121605993 Common - phasin family protein Pnap_3102 16 COG5490 COG5490, Uncharacterized conserved protein Function unknown 121606971 Common - phosphatidylserine decarboxylase Pnap_4088 95 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 121603650 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein Pnap_0739 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 121605822 Common - Pirin domain protein domain protein Pnap_2931 146 COG1741 COG1741, Pirin-related protein General function prediction only 121605276 Common - multi-sensor hybrid histidine kinase Pnap_2377 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 121604883 Common - Inositol phosphatase/fructose-1,6-bisphosphatase Pnap_1982 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 121604918 Common - extracellular solute-binding protein, family 5 Pnap_2017 132 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 121605626 Nonpathogen - hypothetical protein Pnap_2732 2 None None None 121606939 Common - transketolase Pnap_4056 221 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 121604304 Common - hypothetical protein Pnap_1398 17 COG2378 COG2378, Predicted transcriptional regulator Transcription 121605872 Common - Peptidoglycan-binding domain 1 protein Pnap_2981 71 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 121606744 Common - Sel1 domain protein repeat-containing protein Pnap_3856 93 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 121606854 Common - esterase YpfH Pnap_3967 10 COG0400 COG0400, Predicted esterase General function prediction only 121603597 Common - protein of unknown function DUF140 Pnap_0686 149 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 121605378 Common - aldehyde dehydrogenase Pnap_2482 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 121603450 Common - Rhodanese domain protein Pnap_0538 41 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 121604365 Common - hypothetical protein Pnap_1459 11 None None None 121603514 Common - transcriptional regulator, MarR family Pnap_0603 82 COG1846 MarR, Transcriptional regulators Transcription 121604968 Common - PfkB domain protein Pnap_2067 149 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 121603113 Common - putative transmembrane protein Pnap_0196 75 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 121604186 Common - transposase IS200-family protein Pnap_1279 76 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 121605965 Nonpathogen - hypothetical protein Pnap_3074 2 None None None 121606788 Common - RND efflux system, outer membrane lipoprotein, NodT family Pnap_3900 105 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 121606656 Common - integrase Pnap_3768 25 None None None