Mycobacterium vanbaalenii PYR-1, complete genome NC_008726 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 120406030 Common - protein kinase Mvan_5082 146 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 120406474 Common - FAD linked oxidase domain protein Mvan_5531 37 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 120403215 Nonpathogen - hypothetical protein Mvan_2224 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 120405819 Common - succinyl-CoA synthetase subunit alpha Mvan_4869 213 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 120406296 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mvan_5348 147 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 120402595 Common - succinate dehydrogenase, cytochrome b subunit Mvan_1589 22 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 120403075 Common - phosphoserine phosphatase SerB Mvan_2083 152 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 120404896 Common - Silent information regulator protein Sir2 Mvan_3942 148 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 120403631 Common aroK shikimate kinase Mvan_2646 199 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 120401319 Common - extracellular solute-binding protein, family 3 Mvan_0293 116 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 120402361 Common - RNA polymerase sigma factor SigL Mvan_1350 147 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 120404016 Common - Limonene-1,2-epoxide hydrolase Mvan_3036 1 None None None 120401775 Common - Cupin 2, conserved barrel domain protein Mvan_0760 15 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 120402602 Nonpathogen - hypothetical protein Mvan_1596 1 None None None 120404593 Common - Amidohydrolase 3 Mvan_3625 87 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 120404255 Common - Catechol O-methyltransferase Mvan_3280 35 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 120406825 Common - Radical SAM domain protein Mvan_5883 121 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 120402065 Common - response regulator receiver and ANTAR domain protein Mvan_1050 12 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 120403431 Common - LexA repressor Mvan_2441 173 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 120405974 Common - citrate synthase 2 Mvan_5025 192 COG0372 GltA, Citrate synthase Energy production and conversion 120404146 Common - transcriptional regulator, TetR family Mvan_3167 31 COG1309 AcrR, Transcriptional regulator Transcription 120403599 Common - hypothetical protein Mvan_2614 5 COG3427 COG3427, Uncharacterized conserved protein Function unknown 120404736 Common - short-chain dehydrogenase/reductase SDR Mvan_3777 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120402409 Common - ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent Mvan_1398 227 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 120404312 Common - hypothetical protein Mvan_3338 18 None None None 120405550 Common - hypothetical protein Mvan_4598 4 None None None 120405949 Common - RNA polymerase sigma factor Mvan_5000 4 None None None 120405460 Common - glycosyl transferase, family 2 Mvan_4508 100 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 120402786 Common - isochorismate synthases Mvan_1787 223 COG1169 MenF, Isochorismate synthase Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120406071 Common - Linocin_M18 bacteriocin protein Mvan_5123 20 COG1659 COG1659, Uncharacterized protein, linocin/CFP29 homolog Function unknown 120402785 Common - GCN5-related N-acetyltransferase Mvan_1786 79 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 120403166 Common - acylphosphatase Mvan_2174 112 COG1254 AcyP, Acylphosphatases Energy production and conversion 120401679 Common - major facilitator superfamily MFS_1 Mvan_0664 150 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 120403576 Common - hypothetical protein Mvan_2591 20 COG4547 CobT, Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase) Coenzyme metabolism 120403775 Common - hypothetical protein Mvan_2791 6 None None None 120404823 Nonpathogen - conserved hypothetical protein, PE_PGRS Mvan_3865 1 None None None 120402456 Common - peptidase S8 and S53, subtilisin, kexin, sedolisin Mvan_1445 85 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 120402874 Common - NADH dehydrogenase subunit J Mvan_1876 43 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 120406483 Common - Thioesterase Mvan_5540 52 COG3208 GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 120405982 Common - phosphoserine aminotransferase Mvan_5033 158 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 120406184 Common - 4-oxalocrotonate decarboxylase Mvan_5236 67 COG3971 COG3971, 2-keto-4-pentenoate hydratase Secondary metabolites biosynthesis, transport, and catabolism 120405286 Common - F0F1 ATP synthase subunit B Mvan_4332 13 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 120403446 Common - protein of unknown function DUF952 Mvan_2456 46 COG3502 COG3502, Uncharacterized protein conserved in bacteria Function unknown 120401229 Common - transcriptional regulator, TetR family Mvan_0202 3 COG1309 AcrR, Transcriptional regulator Transcription 120402148 Nonpathogen - hypothetical protein Mvan_1135 1 None None None 120402341 Common - Gamma-glutamyltransferase Mvan_1330 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 120404830 Common - sulfate ABC transporter, ATPase subunit Mvan_3872 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 120405953 Common - hypothetical protein Mvan_5004 37 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 120403904 Common - glutamine amidotransferase, class-II Mvan_2921 71 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 120403021 Common - short-chain dehydrogenase/reductase SDR Mvan_2027 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120404330 Common rpsA 30S ribosomal protein S1 Mvan_3356 230 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 120402121 Common - hypothetical protein Mvan_1107 42 COG2251 COG2251, Predicted nuclease (RecB family) General function prediction only 120403728 Common - transcriptional regulator, TetR family Mvan_2744 69 COG1309 AcrR, Transcriptional regulator Transcription 120405630 Common purT phosphoribosylglycinamide formyltransferase 2 Mvan_4678 205 COG0027 PurT, Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Nucleotide transport and metabolism 120402418 Common - acetyl-CoA synthetase Mvan_1407 221 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 120402953 Common - hypothetical protein Mvan_1957 13 COG4329 COG4329, Predicted membrane protein Function unknown 120401146 Common - helix-turn-helix- domain containing protein, AraC type Mvan_0118 47 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 120401641 Common - isoniazid inductible gene protein IniC Mvan_0625 16 COG0699 COG0699, Predicted GTPases (dynamin-related) General function prediction only 120402523 Common - FAD dependent oxidoreductase Mvan_1514 56 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 120404868 Common - ComEC/Rec2-related protein Mvan_3914 38 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 120403306 Common rbfA ribosome-binding factor A Mvan_2315 79 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 120405406 Common - helix-turn-helix- domain containing protein, AraC type Mvan_4454 27 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 120401172 Common - hypothetical protein Mvan_0144 2 None None None 120404301 Common rpmI 50S ribosomal protein L35 Mvan_3327 172 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 120401278 Common - AMP-dependent synthetase and ligase Mvan_0252 216 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120402735 Common - hypothetical protein Mvan_1735 15 None None None 120405302 Common - homoserine dehydrogenase Mvan_4348 194 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 120401208 Common - ATPase associated with various cellular activities, AAA_3 Mvan_0180 179 COG0714 COG0714, MoxR-like ATPases General function prediction only 120402397 Common - UspA domain protein Mvan_1386 54 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 120405031 Common - peptidase S15 Mvan_4077 11 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 120406247 Common - short-chain dehydrogenase/reductase SDR Mvan_5299 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120405265 Common - hypothetical protein Mvan_4311 90 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120405994 Common - putative cold-shock DNA-binding domain protein Mvan_5045 168 COG1278 CspC, Cold shock proteins Transcription 120406267 Common - ABC transporter-related protein Mvan_5319 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 120404660 Nonpathogen - hypothetical protein Mvan_3698 3 None None None 120406479 Common - hypothetical protein Mvan_5536 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 120406525 Common - protein of unknown function DUF732 Mvan_5583 1 None None None 120403195 Common - transcriptional regulator, TrmB Mvan_2204 209 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 120404951 Common - short-chain dehydrogenase/reductase SDR Mvan_3997 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120406156 Common - acyl-CoA synthetase Mvan_5208 216 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120404309 Common - hypothetical protein Mvan_3335 3 None None None 120406729 Common - NUDIX hydrolase Mvan_5787 105 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 120405875 Common - protein of unknown function DUF867 Mvan_4925 26 COG4195 COG4195, Phage-related replication protein General function prediction only 120404347 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mvan_3373 40 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 120405083 Common - 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Mvan_4129 185 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 120406443 Common - phage integrase family protein Mvan_5498 128 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 120406654 Common - cytochrome P450 Mvan_5712 74 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120404468 Common - transcriptional regulator, TetR family Mvan_3496 6 COG1309 AcrR, Transcriptional regulator Transcription 120401958 Common - AMP-dependent synthetase and ligase Mvan_0943 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120404981 Common - Methyltransferase type 12 Mvan_4027 85 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 120403741 Common - hypothetical protein Mvan_2757 7 None None None 120405393 Common - ABC transporter-related protein Mvan_4440 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 120402227 Common - putative conserved membrane protein Mvan_1215 3 None None None 120401976 Common - virulence factor Mce family protein Mvan_0961 23 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120402740 Common - amino acid permease-associated region Mvan_1740 140 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 120401263 Common - bifunctional deaminase-reductase-like protein Mvan_0237 61 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 120403423 Common - conserved hypothetical alanine rich protein Mvan_2433 6 COG3885 COG3885, Uncharacterized conserved protein Function unknown 120403760 Common - transcriptional regulator, TetR family Mvan_2776 37 COG1309 AcrR, Transcriptional regulator Transcription 120403916 Common - Helix-turn-helix, type 11 domain protein Mvan_2933 80 COG2378 COG2378, Predicted transcriptional regulator Transcription 120405324 Common - hypothetical protein Mvan_4370 10 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 120406733 Common - putative methylase Mvan_5791 28 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 120401648 Common - pyruvate kinase Mvan_0632 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 120406465 Common - two component transcriptional regulator, LuxR family Mvan_5522 209 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 120403411 Common recX recombination regulator RecX Mvan_2421 22 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 120406472 Common - cell wall hydrolase/autolysin Mvan_5529 39 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 120406037 Common - phosphate ABC transporter, ATPase subunit Mvan_5089 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 120402716 Common - prevent-host-death family protein Mvan_1716 2 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 120404260 Common - hypothetical protein Mvan_3285 19 COG4825 COG4825, Uncharacterized membrane-anchored protein conserved in bacteria Function unknown 120402776 Common - ybaK/ebsC protein Mvan_1777 102 COG2606 EbsC, Uncharacterized conserved protein Function unknown 120405604 Common - PhoH family protein Mvan_4652 198 COG1875 COG1875, Predicted ATPase related to phosphate starvation-inducible protein PhoH Signal transduction mechanisms 120406224 Common - hypothetical protein Mvan_5276 32 COG3195 COG3195, Uncharacterized protein conserved in bacteria Function unknown 120403337 Common - hypothetical protein Mvan_2346 5 None None None 120405639 Common - Patatin Mvan_4687 128 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 120402251 Common - Cyclopropane-fatty-acyl-phospholipid synthase Mvan_1239 126 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 120402486 Common - putative transcriptional regulator, TetR family Mvan_1477 10 None None None 120406533 Common - acetyl-CoA hydrolase/transferase Mvan_5591 101 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 120406326 Common - tRNA(Ile)-lysidine synthetase Mvan_5378 38 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 120402792 Common - hypothetical protein Mvan_1793 1 COG5373 COG5373, Predicted membrane protein Function unknown 120401415 Common - helix-turn-helix domain protein Mvan_0390 10 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 120406693 Common - beta-phosphoglucomutase family hydrolase Mvan_5751 102 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 120403796 Common - ABC transporter-related protein Mvan_2812 249 COG1119 ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA Inorganic ion transport and metabolism 120405940 Common - hypothetical protein Mvan_4991 102 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 120405810 Common - Alkanesulfonate monooxygenase Mvan_4860 86 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120404185 Common - anti-sigma-factor antagonist Mvan_3207 4 None None None 120403710 Common - cytochrome oxidase assembly Mvan_2726 18 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 120405454 Common - hypothetical protein Mvan_4502 3 None None None 120406009 Nonpathogen - hypothetical protein Mvan_5061 1 None None None 120404181 Common - phage SPO1 DNA polymerase-related protein Mvan_3202 149 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 120406278 Common - permease Mvan_5330 31 COG0701 COG0701, Predicted permeases General function prediction only 120406514 Common - aminoglycoside phosphotransferase Mvan_5572 24 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 120406545 Common - aminoglycoside phosphotransferase Mvan_5603 58 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 120403067 Common - aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding Mvan_2075 117 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 120406152 Common - protein of unknown function DUF140 Mvan_5204 150 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 120401318 Common - polar amino acid ABC transporter, inner membrane subunit Mvan_0292 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 120404389 Common - hypothetical protein Mvan_3416 5 None None None 120402863 Common - alpha/beta hydrolase fold Mvan_1865 134 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120403707 Common - hypothetical protein Mvan_2723 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 120405701 Common - flavin reductase domain protein, FMN-binding Mvan_4751 8 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 120405159 Common - acyl-CoA dehydrogenase domain protein Mvan_4205 164 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120405792 Common - peptidase S1 and S6, chymotrypsin/Hap Mvan_4842 221 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 120405801 Common - enoyl-CoA hydratase Mvan_4851 177 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120403502 Nonpathogen - hypothetical protein Mvan_2514 1 None None None 120402619 Common - transcriptional regulator, TetR family Mvan_1613 72 COG1309 AcrR, Transcriptional regulator Transcription 120404571 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase Mvan_3602 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 120403316 Common - hypothetical protein Mvan_2325 2 None None None 120404500 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase Mvan_3528 213 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 120405904 Common - acyl-CoA dehydrogenase domain protein Mvan_4955 115 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120403363 Nonpathogen - hypothetical protein Mvan_2372 1 None None None 120404822 Common - Rieske (2Fe-2S) domain protein Mvan_3864 48 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 120404642 Common - copper-translocating P-type ATPase Mvan_3678 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 120405682 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Mvan_4731 39 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 120401923 Common - Rieske (2Fe-2S) domain protein Mvan_0908 82 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 120403791 Common hisH imidazole glycerol phosphate synthase subunit HisH Mvan_2807 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 120405719 Common - protein of unknown function DUF501 Mvan_4769 26 COG1507 COG1507, Uncharacterized conserved protein Function unknown 120405964 Nonpathogen - hypothetical protein Mvan_5015 1 None None None 120401667 Common - transcriptional regulator, MarR family Mvan_0651 7 COG1846 MarR, Transcriptional regulators Transcription 120401574 Common - transposase, IS4 family protein Mvan_0553 26 None None None 120404005 Common - Cyclopropane-fatty-acyl-phospholipid synthase Mvan_3025 130 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 120404325 Common - protein of unknown function DUF402 Mvan_3351 6 COG2306 COG2306, Uncharacterized conserved protein Function unknown 120405074 Common - Redoxin domain protein Mvan_4120 223 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 120401901 Common - glycosyl transferase, family 2 Mvan_0886 142 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 120403201 Common tsf elongation factor Ts Mvan_2210 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 120403590 Common - hypothetical protein Mvan_2605 4 COG4640 COG4640, Predicted membrane protein Function unknown 120401734 Common - transcriptional regulator, TetR family Mvan_0719 67 COG1309 AcrR, Transcriptional regulator Transcription 120406416 Common - Methyltransferase type 11 Mvan_5469 11 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 120406273 Common - ABC-3 protein Mvan_5325 54 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 120403474 Common - hypothetical protein Mvan_2484 1 None None None 120401505 Common - aromatic-ring-hydroxylating dioxygenase, beta subunit Mvan_0483 28 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 120403413 Nonpathogen - hypothetical protein Mvan_2423 1 None None None 120406412 Common - putative transcriptional regulator, XRE family Mvan_5465 41 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 120403976 Common - hypothetical protein Mvan_2994 1 None None None 120403052 Common - metal dependent phosphohydrolase Mvan_2058 151 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 120403318 Common - metallophosphoesterase Mvan_2327 11 COG1409 Icc, Predicted phosphohydrolases General function prediction only 120402990 Common - acyl-CoA synthetase Mvan_1995 200 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120404267 Common - HAD-superfamily hydrolase, subfamily IIA Mvan_3292 112 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 120403206 Common - protein of unknown function DUF214 Mvan_2215 1 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 120402749 Common - Alpha/beta hydrolase fold-3 domain protein Mvan_1749 50 COG0657 Aes, Esterase/lipase Lipid metabolism 120401369 Common - Enoyl-CoA hydratase/isomerase Mvan_0344 175 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120402857 Common - isochorismatase hydrolase Mvan_1859 73 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 120403644 Common pyrB aspartate carbamoyltransferase catalytic subunit Mvan_2660 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 120402724 Nonpathogen - hypothetical protein Mvan_1724 1 None None None 120403564 Common - thioester reductase domain Mvan_2578 205 COG3320 COG3320, Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 120402847 Common - hypothetical protein Mvan_1849 11 COG1141 Fer, Ferredoxin Energy production and conversion 120403235 Common - Alpha/beta hydrolase fold-3 domain protein Mvan_2244 106 COG0657 Aes, Esterase/lipase Lipid metabolism 120406759 Common - phospholipid/glycerol acyltransferase Mvan_5817 28 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 120402100 Nonpathogen - hypothetical protein Mvan_1086 1 None None None 120402673 Common - diguanylate phosphodiesterase Mvan_1667 146 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 120402554 Nonpathogen - hypothetical protein Mvan_1547 1 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 120402564 Nonpathogen - hypothetical protein Mvan_1557 1 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 120402691 Common - Heparinase II/III family protein Mvan_1686 30 COG5360 COG5360, Uncharacterized protein conserved in bacteria Function unknown 120403480 Common - AFG1-family ATPase Mvan_2491 91 COG1485 COG1485, Predicted ATPase General function prediction only 120406048 Common - hypothetical protein Mvan_5100 7 None None None 120401202 Common - protein of unknown function DUF305 Mvan_0174 40 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 120405429 Common kgd alpha-ketoglutarate decarboxylase Mvan_4477 193 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 120404801 Common - FAD dependent oxidoreductase Mvan_3843 9 COG3486 IucD, Lysine/ornithine N-monooxygenase Secondary metabolites biosynthesis, transport, and catabolism 120402694 Common - AAA ATPase Mvan_1689 60 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 120401932 Common - hypothetical protein Mvan_0917 3 None None None 120406335 Common - peptidase M1, membrane alanine aminopeptidase Mvan_5387 133 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 120404258 Common - CTP synthetase Mvan_3283 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 120406520 Common - Amine oxidase (flavin-containing) Mvan_5578 64 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 120402191 Common - Threonine aldolase Mvan_1179 119 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 120405008 Common - 2OG-Fe(II) oxygenase Mvan_4054 51 COG3491 PcbC, Isopenicillin N synthase and related dioxygenases General function prediction only 120406803 Common - hypothetical protein Mvan_5861 4 None None None 120406055 Common - extracellular solute-binding protein, family 3 Mvan_5107 113 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 120405134 Common - cytochrome P450 Mvan_4180 82 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120403277 Nonpathogen - PE-PGRS family protein Mvan_2286 1 None None None 120404271 Common - ABC transporter-related protein Mvan_3296 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 120404779 Common - hypothetical protein Mvan_3821 4 None None None 120405549 Common - hypothetical protein Mvan_4597 3 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 120405862 Common - protein of unknown function DUF222 Mvan_4912 7 None None None 120402029 Common - protein of unknown function DUF88 Mvan_1014 68 COG1432 COG1432, Uncharacterized conserved protein Function unknown 120403992 Common - Formate dehydrogenase Mvan_3010 178 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 120404796 Common - hypothetical protein Mvan_3838 13 COG5450 COG5450, Transcription regulator of the Arc/MetJ class Transcription 120404990 Common clpX ATP-dependent protease ATP-binding subunit Mvan_4036 223 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 120403942 Common - protein of unknown function DUF664 Mvan_2959 13 None None None 120406355 Nonpathogen - hypothetical protein Mvan_5408 1 None None None 120401629 Common - Alpha/beta hydrolase fold-3 domain protein Mvan_0613 129 COG0657 Aes, Esterase/lipase Lipid metabolism 120402978 Common - AMP-dependent synthetase and ligase Mvan_1982 220 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120405124 Common - hypothetical protein Mvan_4170 6 COG1141 Fer, Ferredoxin Energy production and conversion 120405696 Common - hypothetical protein Mvan_4746 1 None None None 120405344 Common - 4-hydroxy-2-ketovalerate aldolase Mvan_4391 47 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 120403010 Common - aminoglycoside phosphotransferase Mvan_2016 11 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 120406835 Common - Erythromycin esterase Mvan_5893 7 COG2312 COG2312, Erythromycin esterase homolog General function prediction only 120403787 Common - hypothetical protein Mvan_2803 3 None None None 120404999 Nonpathogen - hypothetical protein Mvan_4045 1 None None None 120402359 Common adk adenylate kinase Mvan_1348 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 120402999 Common - aldehyde dehydrogenase Mvan_2005 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 120405169 Common - amidohydrolase Mvan_4215 87 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 120401518 Common - transposase, IS4 family protein Mvan_0496 57 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 120401889 Common - hypothetical protein Mvan_0874 3 None None None 120403039 Common - transcriptional regulator, LysR family Mvan_2045 60 COG0583 LysR, Transcriptional regulator Transcription 120404344 Common - ABC transporter-related protein Mvan_3370 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 120406237 Common - acyl-CoA dehydrogenase domain protein Mvan_5289 102 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120404229 Nonpathogen - hypothetical protein Mvan_3253 1 None None None 120404451 Common - inositol monophosphatase Mvan_3479 120 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 120402291 Common - 30S ribosomal protein S7 Mvan_1280 247 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 120401499 Common - phage integrase family protein Mvan_0476 6 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 120403240 Common - Alcohol dehydrogenase, zinc-binding domain protein Mvan_2249 92 COG2130 COG2130, Putative NADP-dependent oxidoreductases General function prediction only 120404131 Common - FAD dependent oxidoreductase Mvan_3152 27 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 120405589 Nonpathogen - hypothetical protein Mvan_4637 1 None None None 120402323 Common rplP 50S ribosomal protein L16 Mvan_1312 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 120402036 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Mvan_1021 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 120405771 Common - Carboxymuconolactone decarboxylase Mvan_4821 85 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 120404292 Common pheS phenylalanyl-tRNA synthetase subunit alpha Mvan_3317 248 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 120402202 Common - putative esterase Mvan_1190 11 COG0627 COG0627, Predicted esterase General function prediction only 120402579 Common - Betaine-aldehyde dehydrogenase Mvan_1572 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 120405067 Common - nickel-dependent hydrogenase, large subunit Mvan_4113 98 COG3259 FrhA, Coenzyme F420-reducing hydrogenase, alpha subunit Energy production and conversion 120402946 Common - Camphor resistance CrcB protein Mvan_1949 18 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 120403017 Common - hypothetical protein Mvan_2023 3 None None None 120404398 Common cobN cobaltochelatase Mvan_3426 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 120406915 Common - hypothetical protein Mvan_5982 6 COG1432 COG1432, Uncharacterized conserved protein Function unknown 120404727 Common - beta-lactamase domain protein Mvan_3768 213 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 120405659 Nonpathogen - hypothetical protein Mvan_4707 1 None None None 120404986 Common - oxidoreductase alpha (molybdopterin) subunit Mvan_4032 174 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 120402084 Nonpathogen - hypothetical protein Mvan_1069 2 None None None 120405048 Common - hypothetical protein Mvan_4094 4 None None None 120401620 Common - transposase, mutator type Mvan_0604 82 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 120405899 Common - 3-oxoacyl-(acyl carrier protein) synthase II Mvan_4950 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120406454 Common - glutamate synthase, alpha subunit domain protein Mvan_5511 52 COG0070 GltB, Glutamate synthase domain 3 Amino acid transport and metabolism 120406641 Common - uncharacterized domain 1 Mvan_5699 4 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 120404359 Common - major facilitator superfamily MFS_1 Mvan_3385 75 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 120401920 Common - AMP-dependent synthetase and ligase Mvan_0905 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120406551 Common - phosphodiesterase, MJ0936 family Mvan_5609 40 COG0622 COG0622, Predicted phosphoesterase General function prediction only 120402204 Common - glycogen/starch/alpha-glucan phosphorylases Mvan_1192 136 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 120401490 Common - 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase Mvan_0466 227 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120401712 Common - beta-lactamase domain protein Mvan_0697 67 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 120404395 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Mvan_3422 13 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 120405542 Common - GntR domain protein Mvan_4590 73 COG2186 FadR, Transcriptional regulators Transcription 120401188 Common - permease for cytosine/purines, uracil, thiamine, allantoin Mvan_0160 29 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 120404755 Common - putative GAF sensor protein Mvan_3797 99 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 120401719 Common - extracellular solute-binding protein, family 3 Mvan_0704 173 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 120402538 Common dnaE2 error-prone DNA polymerase Mvan_1530 217 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 120403621 Common - regulatory protein, ArsR Mvan_2636 75 COG1777 COG1777, Predicted transcriptional regulators Transcription 120401337 Common - MMPL domain protein Mvan_0312 71 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 120403002 Common - short-chain dehydrogenase/reductase SDR Mvan_2008 223 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120405144 Common - Rieske (2Fe-2S) domain protein Mvan_4190 81 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 120401938 Common - virulence factor Mce family protein Mvan_0923 60 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120405844 Common - regulatory proteins, IclR Mvan_4894 104 COG1414 IclR, Transcriptional regulator Transcription 120405745 Common - ABC-2 type transporter Mvan_4795 133 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 120403661 Common - glycosyl transferase, family 2 Mvan_2677 27 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 120405987 Common - Activator of Hsp90 ATPase 1 family protein Mvan_5038 8 COG3832 COG3832, Uncharacterized conserved protein Function unknown 120405710 Common - potassium-transporting ATPase subunit B Mvan_4760 232 COG2216 KdpB, High-affinity K+ transport system, ATPase chain B Inorganic ion transport and metabolism 120405193 Common - NADPH-dependent FMN reductase Mvan_4239 44 COG0431 COG0431, Predicted flavoprotein General function prediction only 120405650 Common - response regulator receiver and unknown domain protein Mvan_4698 45 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 120403007 Common - Cyclohexanone monooxygenase Mvan_2013 55 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 120402472 Common - conserved hypothetical alanine and valine rich protein Mvan_1463 1 None None None 120404853 Common - phage integrase family protein Mvan_3897 5 None None None 120401706 Nonpathogen - hypothetical protein Mvan_0691 2 None None None 120403849 Common - flavin reductase domain protein, FMN-binding Mvan_2866 121 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 120406386 Common - Anion-transporting ATPase Mvan_5439 44 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 120403540 Common - response regulator receiver and ANTAR domain protein Mvan_2553 13 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 120403330 Common - hypothetical protein Mvan_2339 5 None None None 120403376 Common - diguanylate cyclase Mvan_2385 175 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 120401781 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Mvan_0766 2 None None None 120406715 Common - protein of unknown function UPF0089 Mvan_5773 28 None None None 120401530 Nonpathogen - hypothetical protein Mvan_0508 2 COG4454 COG4454, Uncharacterized copper-binding protein Inorganic ion transport and metabolism 120404770 Common - hypothetical protein Mvan_3812 4 None None None 120402105 Common - Integrase, catalytic region Mvan_1091 145 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 120402058 Common - transglutaminase domain protein Mvan_1043 73 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 120406937 Nonpathogen - protein of unknown function DUF201 Mvan_6005 2 COG2232 COG2232, Predicted ATP-dependent carboligase related to biotin carboxylase General function prediction only 120403339 Common - bifunctional riboflavin kinase/FMN adenylyltransferase Mvan_2348 208 COG0196 RibF, FAD synthase Coenzyme metabolism 120403748 Common - arginine/ornithine transport system ATPase Mvan_2764 99 COG1703 ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family Amino acid transport and metabolism 120401724 Common - sulfur carrier protein ThiS Mvan_0709 23 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 120402626 Common - FAD dependent oxidoreductase Mvan_1620 148 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 120404871 Common - acyl-CoA dehydrogenase domain protein Mvan_3917 151 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120402308 Common - (S)-2-hydroxy-acid oxidase Mvan_1297 122 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 120402390 Common - putative conserved transmembrane protein Mvan_1379 3 None None None 120404141 Common - preprotein translocase subunit SecA Mvan_3162 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 120405354 Common - protein of unknown function DUF140 Mvan_4401 148 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 120402610 Common - putative GAF sensor protein Mvan_1604 39 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 120406765 Common - hypothetical protein Mvan_5823 14 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 120404541 Common - hypothetical protein Mvan_3570 17 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 120401793 Common - transcriptional regulator, TetR family Mvan_0778 67 COG1309 AcrR, Transcriptional regulator Transcription 120401159 Common - acyl-CoA synthetase Mvan_0131 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120404481 Common - hypothetical protein Mvan_3509 11 None None None 120405383 Common - binding-protein-dependent transport systems inner membrane component Mvan_4430 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 120405402 Nonpathogen - hypothetical protein Mvan_4450 1 None None None 120406428 Common - aminotransferase, class V Mvan_5482 162 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 120403822 Common - Ferritin, Dps family protein Mvan_2838 126 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 120403107 Common gatA aspartyl/glutamyl-tRNA amidotransferase subunit A Mvan_2115 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 120403717 Common - FeS assembly protein SufB Mvan_2733 186 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 120402686 Common - hypothetical protein Mvan_1680 8 None None None 120402918 Nonpathogen - hypothetical protein Mvan_1921 1 None None None 120402257 Common - protein of unknown function DUF664 Mvan_1245 13 None None None 120406816 Common - UbiC transcription regulator-associated domain protein Mvan_5874 133 COG2188 PhnF, Transcriptional regulators Transcription 120406114 Common - short-chain dehydrogenase/reductase SDR Mvan_5166 195 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120403709 Common - hypothetical protein Mvan_2725 19 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 120404807 Common - amino acid adenylation domain Mvan_3849 218 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 120404206 Common - BioY protein Mvan_3228 103 COG1268 BioY, Uncharacterized conserved protein General function prediction only 120401580 Common - protocatechuate 3,4-dioxygenase, alpha subunit Mvan_0561 38 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 120406791 Common - FdxD Mvan_5849 12 COG1141 Fer, Ferredoxin Energy production and conversion 120402402 Common - arginine deiminase Mvan_1391 54 COG2235 ArcA, Arginine deiminase Amino acid transport and metabolism 120404053 Common - Transglycosylase-associated protein Mvan_3074 1 COG2261 COG2261, Predicted membrane protein Function unknown 120403884 Common - transcriptional regulator, TetR family Mvan_2901 8 COG1309 AcrR, Transcriptional regulator Transcription 120406991 Common - NUDIX hydrolase Mvan_6062 63 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 120406438 Common - 30S ribosomal protein S18 Mvan_5492 25 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 120405563 Common - Limonene-1,2-epoxide hydrolase Mvan_4611 9 COG4308 LimA, Limonene-1,2-epoxide hydrolase Secondary metabolites biosynthesis, transport, and catabolism 120404064 Common - uncharacterized domain 1 Mvan_3085 64 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 120405457 Common - hypothetical protein Mvan_4505 16 None None None 120405315 Common - phage major capsid protein, HK97 Mvan_4361 46 COG4653 COG4653, Predicted phage phi-C31 gp36 major capsid-like protein General function prediction only 120403085 Common - amino acid carrier protein Mvan_2093 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 120401948 Common - Asp/Glu racemase Mvan_0933 45 COG4126 COG4126, Hydantoin racemase Amino acid transport and metabolism 120402172 Common - putative transcriptional regulator, MerR family Mvan_1160 136 COG0789 SoxR, Predicted transcriptional regulators Transcription 120403154 Common - Alpha/beta hydrolase fold-3 domain protein Mvan_2162 135 COG0657 Aes, Esterase/lipase Lipid metabolism 120404214 Common - DSBA oxidoreductase Mvan_3237 72 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 120405526 Common - DoxX family protein Mvan_4574 19 COG2259 COG2259, Predicted membrane protein Function unknown 120403549 Common - Phosphatidylinositol alpha-mannosyltransferase Mvan_2562 209 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 120405477 Common - Proline dehydrogenase Mvan_4525 126 COG0506 PutA, Proline dehydrogenase Amino acid transport and metabolism 120403721 Common - SUF system FeS assembly protein, NifU family Mvan_2737 124 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 120401463 Common - extracellular solute-binding protein, family 5 Mvan_0438 157 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 120401064 Common - protein of unknown function DUF1016 Mvan_0036 50 COG4804 COG4804, Uncharacterized conserved protein Function unknown 120402300 Common - putative transcriptional regulator, AsnC family Mvan_1289 155 COG1522 Lrp, Transcriptional regulators Transcription 120402811 Common - hypothetical protein Mvan_1812 26 COG5282 COG5282, Uncharacterized conserved protein Function unknown 120402156 Common - transcriptional modulator of MazE/toxin, MazF Mvan_1144 52 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 120404117 Common - protein of unknown function DUF1290 Mvan_3138 25 COG3856 Sbp, Uncharacterized conserved protein (small basic protein) Function unknown 120401487 Common - ring hydroxylating dioxygenase, alpha subunit Mvan_0463 84 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 120403254 Common - GCN5-related N-acetyltransferase Mvan_2263 14 COG3393 COG3393, Predicted acetyltransferase General function prediction only 120401115 Nonpathogen - hypothetical protein Mvan_0087 1 None None None 120402379 Common - hypothetical protein Mvan_1368 10 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120402434 Common - HAD-superfamily hydrolase, subfamily IIB Mvan_1423 33 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 120402838 Common - hypothetical protein Mvan_1840 2 None None None 120404948 Common - transcriptional regulator, TetR family Mvan_3994 70 COG1309 AcrR, Transcriptional regulator Transcription 120404785 Nonpathogen - hypothetical protein Mvan_3827 2 None None None 120404684 Common - hypothetical protein Mvan_3724 10 None None None 120404882 Common - amino acid permease-associated region Mvan_3928 94 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 120405485 Common fbiC FO synthase Mvan_4533 84 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 120404410 Common - 5'-3' exonuclease Mvan_3438 216 COG0258 Exo, 5'-3' exonuclease (including N-terminal domain of PolI) DNA replication, recombination, and repair 120401033 Common - hypothetical protein Mvan_0005 20 COG5512 COG5512, Zn-ribbon-containing, possibly RNA-binding protein and truncated derivatives General function prediction only 120403635 Common - peptidase M24 Mvan_2650 246 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 120402158 Common - hypothetical protein Mvan_1146 14 COG3972 COG3972, Superfamily I DNA and RNA helicases General function prediction only 120402369 Common - two component transcriptional regulator, LuxR family Mvan_1358 213 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 120403451 Common - RNA polymerase sigma factor RpoD Mvan_2461 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 120402015 Common - amino acid adenylation domain Mvan_1000 235 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 120401346 Common - transcriptional regulator, TetR family Mvan_0321 6 COG1309 AcrR, Transcriptional regulator Transcription 120404027 Common - protein of unknown function DUF893, YccS/YhfK Mvan_3048 4 COG1289 COG1289, Predicted membrane protein Function unknown 120403952 Common - NLP/P60 protein Mvan_2970 52 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 120405672 Common - hypothetical protein Mvan_4721 33 COG2388 COG2388, Predicted acetyltransferase General function prediction only 120403527 Common - DNA binding domain, excisionase family Mvan_2539 13 COG3585 MopI, Molybdopterin-binding protein Coenzyme metabolism 120405232 Common - transcription factor WhiB Mvan_4278 1 None None None 120401148 Common pntA NAD(P) transhydrogenase subunit alpha Mvan_0120 155 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 120402346 Common rpsN 30S ribosomal protein S14 Mvan_1335 204 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 120403134 Common - cystathionine gamma-lyase Mvan_2142 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 120401217 Common - hypothetical protein Mvan_0190 1 None None None 120402047 Common - transcriptional regulator, HxlR family Mvan_1032 126 COG1733 COG1733, Predicted transcriptional regulators Transcription 120405027 Common - copper resistance D domain protein Mvan_4073 30 COG3336 COG3336, Predicted membrane protein Function unknown 120405785 Common - putative regulatory protein, FmdB family Mvan_4835 18 COG2331 COG2331, Uncharacterized protein conserved in bacteria Function unknown 120402683 Common - carboxyl transferase Mvan_1677 214 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 120406952 Common - extracellular solute-binding protein, family 1 Mvan_6021 67 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 120401447 Common - putative conserved transmembrane protein Mvan_0422 1 None None None 120406089 Common - glycosyl transferase, family 2 Mvan_5141 70 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 120401477 Common - dihydrodipicolinate synthetase Mvan_0452 233 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 120405158 Common - transcriptional regulator, TetR family Mvan_4204 59 COG1309 AcrR, Transcriptional regulator Transcription 120404078 Common - Prostaglandin-endoperoxide synthase Mvan_3099 7 None None None 120404873 Common - short-chain dehydrogenase/reductase SDR Mvan_3919 223 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120406687 Common - hypothetical protein Mvan_5745 9 None None None 120402845 Common - hypothetical protein Mvan_1847 5 None None None 120401764 Common - Vesicle-fusing ATPase Mvan_0749 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 120405868 Common - hypothetical protein Mvan_4918 1 None None None 120405223 Common - hypothetical protein Mvan_4269 89 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120404039 Common - hypothetical protein Mvan_3060 28 COG5579 COG5579, Uncharacterized conserved protein Function unknown 120406429 Common - hypothetical protein Mvan_5483 65 COG4301 COG4301, Uncharacterized conserved protein Function unknown 120402738 Common - hypothetical protein Mvan_1738 7 None None None 120406682 Common - binding-protein-dependent transport systems inner membrane component Mvan_5740 179 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 120404831 Common - sulfate ABC transporter, inner membrane subunit CysW Mvan_3873 232 COG4208 CysW, ABC-type sulfate transport system, permease component Inorganic ion transport and metabolism 120405019 Common - response regulator receiver protein Mvan_4065 52 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 120405332 Common - acyl-CoA dehydrogenase domain protein Mvan_4379 146 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120401294 Common - TspO and MBR like proteins Mvan_0268 60 COG3476 COG3476, Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) Signal transduction mechanisms 120406808 Common - hypothetical protein Mvan_5866 2 None None None 120401459 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Mvan_0434 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 120406585 Common - hypothetical protein Mvan_5643 2 None None None 120401141 Common - alpha/beta hydrolase fold Mvan_0113 90 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120404038 Common - alpha amylase, catalytic region Mvan_3059 156 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 120405436 Common - ABC transporter-related protein Mvan_4484 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 120402465 Common - hypothetical protein Mvan_1455 3 None None None 120402743 Common - Rubredoxin-type Fe(Cys)4 protein Mvan_1743 106 COG1773 COG1773, Rubredoxin Energy production and conversion 120401762 Common - transposase, IS4 family protein Mvan_0747 26 None None None 120402577 Common - hypothetical protein Mvan_1570 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 120404473 Common - integral membrane protein Mvan_3501 12 None None None 120402001 Common - hypothetical protein Mvan_0986 25 COG4325 COG4325, Predicted membrane protein Function unknown 120402751 Nonpathogen - hypothetical protein Mvan_1751 3 None None None 120404908 Common - peptidase S9, prolyl oligopeptidase active site domain protein Mvan_3954 109 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 120405582 Common - penicillin-binding protein, transpeptidase Mvan_4630 166 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 120401675 Common - hypothetical protein Mvan_0660 5 None None None 120401827 Common - hypothetical protein Mvan_0812 3 None None None 120402284 Common - hypothetical protein Mvan_1273 1 None None None 120401035 Common - DNA gyrase, A subunit Mvan_0007 236 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 120405625 Common - hypothetical protein Mvan_4673 9 COG5473 COG5473, Predicted integral membrane protein Function unknown 120401895 Common - 1,4-dihydroxy-2-naphthoate octaprenyltransferase Mvan_0880 69 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 120405090 Common - Enoyl-CoA hydratase/isomerase Mvan_4136 146 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120403458 Common - hypothetical protein Mvan_2468 19 None None None 120406130 Common - protein of unknown function DUF182 Mvan_5182 114 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 120404208 Common - hypothetical protein Mvan_3230 32 None None None 120403083 Common - hypothetical protein Mvan_2091 23 COG1041 COG1041, Predicted DNA modification methylase DNA replication, recombination, and repair 120405640 Common - Patatin Mvan_4688 39 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 120401688 Common - cation diffusion facilitator family transporter Mvan_0673 157 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 120404228 Nonpathogen - transcriptional regulator, Fis family Mvan_3251 2 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 120404741 Nonpathogen - hypothetical protein Mvan_3782 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 120404674 Common - cytochrome c oxidase, subunit III Mvan_3712 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 120405621 Common - hypothetical protein Mvan_4669 2 None None None 120404049 Common - Abortive infection protein Mvan_3070 4 None None None 120405290 Common - glycosyl transferase, family 4 Mvan_4336 179 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 120404787 Common - hypothetical protein Mvan_3829 3 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 120406107 Common - cytochrome P450 Mvan_5159 91 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120401870 Common - transcriptional regulator, TetR family Mvan_0855 7 COG1309 AcrR, Transcriptional regulator Transcription 120406211 Common - putative GAF sensor protein Mvan_5263 74 COG2203 FhlA, FOG: GAF domain Signal transduction mechanisms 120405276 Common - AlkA domain protein Mvan_4322 110 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 120403269 Common - Glutamate--ammonia ligase Mvan_2278 223 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 120404906 Common - hypothetical protein Mvan_3952 4 COG5403 COG5403, Uncharacterized conserved protein Function unknown 120405887 Common - response regulator receiver and ANTAR domain protein Mvan_4938 12 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 120403183 Common - putative conserved alanine rich lipoprotein LppW Mvan_2191 7 None None None 120404939 Common - transcriptional regulator, TetR family Mvan_3985 30 COG1309 AcrR, Transcriptional regulator Transcription 120406828 Common - hypothetical protein Mvan_5886 1 None None None 120406618 Common - hypothetical protein Mvan_5676 1 None None None 120406205 Common - acyl-CoA dehydrogenase domain protein Mvan_5257 100 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120404137 Common - regulatory protein GntR, HTH Mvan_3158 25 COG2188 PhnF, Transcriptional regulators Transcription 120404583 Common - Methyltransferase type 11 Mvan_3615 25 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 120404156 Common - hypothetical protein Mvan_3177 32 None None None 120404551 Common - domain of unknown function DUF1731 Mvan_3580 107 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 120403257 Common - penicillin-binding protein, transpeptidase Mvan_2266 176 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 120404159 Common - ferredoxin Mvan_3180 113 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 120406289 Common - hypothetical protein Mvan_5341 5 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 120404573 Common - acyl-CoA synthetase Mvan_3604 183 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120403630 Common - chorismate synthase Mvan_2645 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 120401485 Nonpathogen - hypothetical protein Mvan_0461 1 None None None 120406047 Common - Thioredoxin domain Mvan_5099 111 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 120401371 Common - carboxyl transferase Mvan_0346 144 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 120405218 Common - hypothetical protein Mvan_4264 3 None None None 120405521 Common - regulatory protein GntR, HTH Mvan_4569 126 COG1725 COG1725, Predicted transcriptional regulators Transcription 120401248 Common - hypothetical protein Mvan_0222 20 COG2030 MaoC, Acyl dehydratase Lipid metabolism 120402311 Common - glucose-methanol-choline oxidoreductase Mvan_1300 90 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 120404523 Common - hypothetical protein Mvan_3551 4 None None None 120403927 Nonpathogen - hypothetical protein Mvan_2944 1 COG4113 COG4113, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 120401282 Common - Beta-N-acetylhexosaminidase Mvan_0256 177 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 120406028 Common - chorismate mutase Mvan_5080 11 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 120404590 Common - protein tyrosine phosphatase Mvan_3622 130 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 120402648 Common - short-chain dehydrogenase/reductase SDR Mvan_1642 205 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 120406648 Common - hypothetical protein Mvan_5706 5 None None None 120406191 Nonpathogen - hypothetical protein Mvan_5243 6 None None None 120403866 Common - FAD dependent oxidoreductase Mvan_2883 70 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 120405339 Common - two component transcriptional regulator, LuxR family Mvan_4386 179 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 120402092 Nonpathogen - hypothetical protein Mvan_1077 1 None None None 120402278 Common - Methyltransferase type 12 Mvan_1267 16 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 120405202 Common - fumarate reductase/succinate dehydrogenase flavoprotein domain protein Mvan_4248 53 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 120403149 Common - Dyp-type peroxidase family Mvan_2157 38 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 120404925 Common - hypothetical protein Mvan_3971 1 None None None 120404607 Nonpathogen - hypothetical protein Mvan_3639 1 None None None 120406989 Common - hypothetical protein Mvan_6060 1 None None None 120404615 Common - helix-turn-helix- domain containing protein, AraC type Mvan_3649 44 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 120402419 Common - Pyruvate dehydrogenase (acetyl-transferring) Mvan_1408 155 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 120405924 Common - ATPase associated with various cellular activities, AAA_5 Mvan_4975 80 COG0714 COG0714, MoxR-like ATPases General function prediction only 120401465 Common - hypothetical protein Mvan_0440 3 None None None 120401402 Common - cobyric acid synthase Mvan_0377 151 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 120402318 Common rplW 50S ribosomal protein L23 Mvan_1307 212 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 120403764 Nonpathogen - hypothetical protein Mvan_2780 3 None None None 120406927 Nonpathogen - hypothetical protein Mvan_5994 1 None None None 120404437 Common - hypothetical protein Mvan_3465 9 None None None 120401837 Common - hypothetical protein Mvan_0822 8 None None None 120401084 Common - UbiC transcription regulator-associated domain protein Mvan_0056 118 COG2188 PhnF, Transcriptional regulators Transcription 120406607 Common - cell envelope-related transcriptional attenuator Mvan_5665 62 COG1316 LytR, Transcriptional regulator Transcription 120406776 Common - protein of unknown function DUF81 Mvan_5834 49 COG0730 COG0730, Predicted permeases General function prediction only 120406627 Common - DNA polymerase IV Mvan_5685 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 120406339 Common - hypothetical protein Mvan_5391 9 None None None 120406703 Common - glutamine cyclotransferase Mvan_5761 26 COG3823 COG3823, Glutamine cyclotransferase Posttranslational modification, protein turnover, chaperones 120405666 Common - hypothetical protein Mvan_4715 7 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 120406117 Common - putative transcriptional regulator, TetR family Mvan_5169 3 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 120405141 Common - transcriptional regulator, MarR family Mvan_4187 42 COG1846 MarR, Transcriptional regulators Transcription 120405167 Common - Rieske (2Fe-2S) domain protein Mvan_4213 81 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 120406573 Common - cell wall arabinan synthesis protein Mvan_5631 5 COG2978 AbgT, Putative p-aminobenzoyl-glutamate transporter Coenzyme metabolism 120406721 Common - cobalamin synthesis protein, P47K Mvan_5779 124 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 120401769 Common - membrane-flanked domain Mvan_0754 14 COG3402 COG3402, Uncharacterized conserved protein Function unknown 120402521 Common - inositol-5-monophosphate dehydrogenase Mvan_1512 221 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 120403402 Common - hypothetical protein Mvan_2411 7 None None None 120401913 Common - AMP-dependent synthetase and ligase Mvan_0898 206 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120405966 Common - hypothetical protein Mvan_5017 1 None None None 120401963 Common - hypothetical protein Mvan_0948 5 None None None 120404276 Common - acyl-CoA synthetase Mvan_3301 61 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 120403116 Common - ketol-acid reductoisomerase Mvan_2124 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 120403944 Common - OsmC-like family protein Mvan_2961 51 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 120406343 Common - putative adenylate/guanylate cyclase Mvan_5395 87 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 120404040 Common - putative esterase Mvan_3061 13 COG0627 COG0627, Predicted esterase General function prediction only 120404560 Nonpathogen - hypothetical protein Mvan_3591 1 None None None 120404490 Common - alanine racemase domain protein Mvan_3518 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 120403140 Common - alpha/beta hydrolase fold Mvan_2148 59 COG2267 PldB, Lysophospholipase Lipid metabolism 120406586 Common - putative esterase Mvan_5644 11 COG0627 COG0627, Predicted esterase General function prediction only 120401812 Common - alpha/beta hydrolase fold Mvan_0797 26 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120406128 Common - hypothetical protein Mvan_5180 7 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 120402183 Common - PilT protein domain protein Mvan_1171 17 COG3742 COG3742, Uncharacterized protein conserved in bacteria Function unknown 120403175 Common - peptidase S11, D-alanyl-D-alanine carboxypeptidase 1 Mvan_2183 148 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 120405228 Common - sulfatase Mvan_4274 27 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 120401814 Common - protein of unknown function DUF955 Mvan_0799 45 COG3800 COG3800, Predicted transcriptional regulator General function prediction only 120405299 Common - transcription termination factor Rho Mvan_4345 210 COG1158 Rho, Transcription termination factor Transcription 120403582 Common - putative conserved membrane protein Mvan_2597 1 None None None 120404978 Common - Rhodanese domain protein Mvan_4024 156 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 120405400 Common - Heavy metal transport/detoxification protein Mvan_4448 86 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 120406783 Common - ABC transporter-related protein Mvan_5841 244 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 120403064 Common - response regulator receiver protein Mvan_2072 22 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 120406744 Common - phospholipase D/Transphosphatidylase Mvan_5802 32 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 120404239 Nonpathogen - hypothetical protein Mvan_3263 1 None None None 120406440 Common - hypothetical protein Mvan_5494 1 None None None 120404169 Common - protein of unknown function DUF732 Mvan_3190 1 None None None 120401714 Common - Endonuclease/exonuclease/phosphatase Mvan_0699 10 COG3021 COG3021, Uncharacterized protein conserved in bacteria Function unknown 120404618 Common - response regulator receiver protein Mvan_3653 185 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 120402891 Common - transcriptional regulator, TetR family Mvan_1893 33 COG1309 AcrR, Transcriptional regulator Transcription 120405020 Common - globin Mvan_4066 63 COG2346 COG2346, Truncated hemoglobins General function prediction only 120406400 Common - hypothetical protein Mvan_5453 10 None None None 120405859 Common - transcriptional regulator, TetR family Mvan_4909 16 COG1309 AcrR, Transcriptional regulator Transcription 120406422 Common - iron-containing alcohol dehydrogenase Mvan_5476 174 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 120401730 Common - Aminopeptidase Y Mvan_0715 65 COG2234 Iap, Predicted aminopeptidases General function prediction only 120406863 Common - twin-arginine translocation pathway signal Mvan_5923 4 None None None 120404930 Common - putative ferredoxin Mvan_3976 16 COG1141 Fer, Ferredoxin Energy production and conversion 120406737 Common - hypothetical protein Mvan_5795 1 None None None 120403320 Common truB tRNA pseudouridine synthase B Mvan_2329 244 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 120401306 Common - hypothetical protein Mvan_0280 1 None None None 120406980 Common - hypothetical protein Mvan_6050 21 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 120403260 Common - hypothetical protein Mvan_2269 9 None None None 120403509 Common - transposase IS3/IS911 family protein Mvan_2521 51 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 120405012 Common - HNH nuclease Mvan_4058 6 None None None 120402219 Nonpathogen - hypothetical protein Mvan_1207 1 None None None 120405555 Common - virulence factor Mce family protein Mvan_4603 58 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120406665 Nonpathogen - integral membrane protein Mvan_5723 3 None None None 120401981 Common - hypothetical protein Mvan_0966 1 None None None 120403539 Nonpathogen - hypothetical protein Mvan_2552 1 None None None 120402800 Common - UvrD/REP helicase Mvan_1801 48 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 120402671 Common - diguanylate cyclase Mvan_1665 176 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 120405726 Common - nucleoside triphosphate pyrophosphohydrolase Mvan_4776 152 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 120403036 Common - ribonucleotide-diphosphate reductase subunit alpha Mvan_2042 219 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 120402636 Common - hypothetical protein Mvan_1630 8 None None None 120403284 Common - cobalt ABC transporter, inner membrane subunit CbiQ Mvan_2293 53 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 120402737 Common manB phosphomannomutase/phosphoglucomutase Mvan_1737 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 120403126 Common - regulatory proteins, IclR Mvan_2134 81 COG1414 IclR, Transcriptional regulator Transcription 120404816 Common - phosphoadenosine phosphosulfate reductase Mvan_3858 154 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 120405052 Common - short-chain dehydrogenase/reductase SDR Mvan_4098 219 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 120406068 Common - glyoxalase/bleomycin resistance protein/dioxygenase Mvan_5120 16 None None None 120401553 Common - hypothetical protein Mvan_0532 3 COG1141 Fer, Ferredoxin Energy production and conversion 120401309 Common - fumarate reductase iron-sulfur subunit Mvan_0283 203 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 120406908 Common - transposase, mutator type Mvan_5974 84 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 120401866 Nonpathogen - putative transmembrane protein Mvan_0851 1 None None None 120403483 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Mvan_2494 3 None None None 120401993 Common - glycosyl transferase, group 1 Mvan_0978 198 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 120404124 Common - aldehyde dehydrogenase Mvan_3145 218 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 120405373 Common - isochorismatase hydrolase Mvan_4420 65 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 120404106 Common - acyl-CoA synthetase Mvan_3127 202 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120405955 Common - ABC transporter-related protein Mvan_5006 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 120405365 Common - 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase Mvan_4412 204 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120405054 Common - oligoribonuclease Mvan_4100 88 COG1949 Orn, Oligoribonuclease (3'->5' exoribonuclease) RNA processing and modification 120403288 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Mvan_2297 165 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 120401187 Common - putative transcriptional regulator, AsnC family Mvan_0159 71 COG1522 Lrp, Transcriptional regulators Transcription 120403044 Common - putative transcriptional regulator Mvan_2050 6 COG2345 COG2345, Predicted transcriptional regulator Transcription 120401104 Common - PE-like protein Mvan_0076 1 None None None 120402904 Common - acyl-CoA dehydrogenase domain protein Mvan_1907 139 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120406784 Common - transcriptional regulator, TetR family Mvan_5842 89 COG1309 AcrR, Transcriptional regulator Transcription 120402298 Common - ornithine aminotransferase Mvan_1287 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 120402989 Common - amidohydrolase 2 Mvan_1994 19 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 120406563 Common - hypothetical protein Mvan_5621 10 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 120403386 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Mvan_2395 187 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 120405259 Common - acetyl-CoA acetyltransferase Mvan_4305 176 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120401162 Common - virulence factor Mce family protein Mvan_0134 8 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120401884 Common - cytochrome c assembly protein Mvan_0869 162 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 120406007 Common - transposase IS3/IS911 family protein Mvan_5059 56 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 120403048 Common - hypothetical protein Mvan_2054 5 None None None 120401874 Common - hypothetical protein Mvan_0859 3 None None None 120406704 Common - Alcohol dehydrogenase GroES domain protein Mvan_5762 184 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 120401743 Common - protein of unknown function DUF222 Mvan_0728 6 None None None 120404376 Common - DoxX family protein Mvan_3403 13 COG2259 COG2259, Predicted membrane protein Function unknown 120403624 Common - protein of unknown function UPF0047 Mvan_2639 108 COG0432 COG0432, Uncharacterized conserved protein Function unknown 120401754 Common - putative monovalent cation/H+ antiporter subunit G Mvan_0739 24 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 120403684 Common - protein of unknown function DUF199 Mvan_2700 46 COG1481 COG1481, Uncharacterized protein conserved in bacteria Function unknown 120406302 Common - Phosphoglycerate mutase Mvan_5354 52 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 120403329 Common - lipid-transfer protein Mvan_2338 176 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120405828 Common - hypothetical protein Mvan_4878 3 None None None 120401395 Nonpathogen - hypothetical protein Mvan_0370 1 COG0657 Aes, Esterase/lipase Lipid metabolism 120402865 Common - FAD dependent oxidoreductase Mvan_1867 67 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 120405643 Common - putative transcriptional regulator, MerR family Mvan_4691 96 COG0789 SoxR, Predicted transcriptional regulators Transcription 120406329 Common - Inorganic diphosphatase Mvan_5381 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 120402939 Common - hypothetical protein Mvan_1942 6 None None None 120401386 Common - protein of unknown function DUF140 Mvan_0361 146 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 120406401 Common - hypothetical protein Mvan_5454 11 None None None 120406630 Common - hypothetical protein Mvan_5688 1 None None None 120401936 Common - protein of unknown function DUF140 Mvan_0921 132 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 120402009 Common - hypothetical protein Mvan_0994 1 None None None 120404661 Common - putative adenylate/guanylate cyclase Mvan_3699 41 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 120406840 Common - DNA gyrase/topoisomerase IV, subunit A Mvan_5898 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 120401234 Nonpathogen - hypothetical protein Mvan_0207 5 None None None 120403050 Common - transcriptional regulator, TetR family Mvan_2056 27 COG1309 AcrR, Transcriptional regulator Transcription 120406258 Common - hypothetical protein Mvan_5310 1 None None None 120401179 Common - putative secreted protein Mvan_0151 17 None None None 120403104 Common ligA NAD-dependent DNA ligase LigA Mvan_2112 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 120403871 Common - Alpha/beta hydrolase fold-3 domain protein Mvan_2888 112 COG0657 Aes, Esterase/lipase Lipid metabolism 120402805 Common - Glutaredoxin-like protein Mvan_1806 22 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 120402934 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Mvan_1937 190 COG0546 Gph, Predicted phosphatases General function prediction only 120404461 Common - hypothetical protein Mvan_3489 188 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 120401898 Common - 2-nitropropane dioxygenase, NPD Mvan_0883 114 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 120401196 Common - hypothetical protein Mvan_0168 14 COG0778 NfnB, Nitroreductase Energy production and conversion 120404764 Common - ABC transporter-related protein Mvan_3806 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 120401525 Nonpathogen - hypothetical protein Mvan_0503 1 None None None 120406576 Common - extracellular solute-binding protein, family 3 Mvan_5634 70 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 120406814 Nonpathogen - Uncharacterized enzyme of phosphonate metabolism-like Mvan_5872 1 COG3625 PhnH, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 120405861 Common - transcriptional regulator, TetR family Mvan_4911 4 COG1309 AcrR, Transcriptional regulator Transcription 120405346 Common - Hydratase/decarboxylase Mvan_4393 67 COG3971 COG3971, 2-keto-4-pentenoate hydratase Secondary metabolites biosynthesis, transport, and catabolism 120402116 Nonpathogen - hypothetical protein Mvan_1102 1 None None None 120404179 Common - RNA binding S1 domain protein Mvan_3200 137 COG2183 Tex, Transcriptional accessory protein Transcription 120403929 Common - cation efflux protein Mvan_2946 12 COG3965 COG3965, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 120405688 Common - hypothetical protein Mvan_4737 8 None None None 120405773 Common - transcriptional regulator, MarR family Mvan_4823 99 COG1846 MarR, Transcriptional regulators Transcription 120401597 Common - integrase, catalytic region Mvan_0580 27 None None None 120401655 Common - Oxidoreductase FAD-binding domain protein Mvan_0639 82 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 120402662 Common - hypothetical protein Mvan_1656 7 None None None 120403802 Common trpA tryptophan synthase subunit alpha Mvan_2818 217 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 120406061 Common - NAD-dependent epimerase/dehydratase Mvan_5113 164 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 120406140 Common - Alpha,alpha-trehalose-phosphate synthase (UDP-forming) Mvan_5192 96 COG0380 OtsA, Trehalose-6-phosphate synthase Carbohydrate transport and metabolism 120404191 Common - LpqJ Mvan_3213 1 None None None 120406947 Nonpathogen - hypothetical protein Mvan_6015 1 None None None 120403070 Common - amino acid permease-associated region Mvan_2078 66 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 120406880 Common - hypothetical protein Mvan_5942 8 COG3655 COG3655, Predicted transcriptional regulator Transcription 120404392 Common - apolipoprotein N-acyltransferase Mvan_3419 140 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 120402651 Common - putative transcriptional regulator, AsnC family Mvan_1645 144 COG1522 Lrp, Transcriptional regulators Transcription 120404956 Common - alpha/beta hydrolase fold Mvan_4002 156 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120403119 Common - hypothetical protein Mvan_2127 51 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 120404110 Common - glycine dehydrogenase Mvan_3131 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 120404910 Common - hypothetical protein Mvan_3956 1 None None None 120406975 Common - hypothetical protein Mvan_6045 46 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120405593 Common - bifunctional deaminase-reductase domain protein Mvan_4641 50 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 120404230 Common - ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member-like protein Mvan_3254 57 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 120401805 Common - putative GAF sensor protein Mvan_0790 81 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 120406166 Common - hypothetical protein Mvan_5218 7 None None None 120404119 Common - CDP-alcohol phosphatidyltransferase Mvan_3140 92 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 120406073 Common - hypothetical protein Mvan_5125 1 None None None 120406894 Common - Integrase, catalytic region Mvan_5959 141 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 120402949 Common - hypothetical protein Mvan_1952 30 None None None 120404290 Common - GCN5-related N-acetyltransferase Mvan_3315 86 COG3153 COG3153, Predicted acetyltransferase General function prediction only 120403666 Nonpathogen - hypothetical protein Mvan_2682 2 None None None 120402162 Nonpathogen - hypothetical protein Mvan_1150 1 None None None 120401563 Common - Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B Mvan_0542 23 None None None 120405934 Nonpathogen - hypothetical protein Mvan_4985 1 None None None 120402826 Common - protein of unknown function DUF156 Mvan_1827 74 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 120405318 Common - phage integrase family protein Mvan_4364 33 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 120405531 Common - enoyl-CoA hydratase Mvan_4579 157 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120402590 Common - transposase IS200-family protein Mvan_1583 74 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 120402078 Nonpathogen - hypothetical protein Mvan_1063 1 None None None 120402332 Common - putative integral membrane protein Mvan_1321 14 None None None 120403756 Common - Asparaginase/glutaminase Mvan_2772 124 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 120406315 Common - hypothetical protein Mvan_5367 6 None None None 120402034 Common - protein of unknown function DUF81 Mvan_1019 18 None None None 120405753 Common - methionyl-tRNA synthetase Mvan_4803 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 120402702 Common - GDP-mannose 6-dehydrogenase Mvan_1699 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 120406102 Common - Carboxymuconolactone decarboxylase Mvan_5154 42 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 120406011 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Mvan_5063 5 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 120404056 Common - luciferase family protein Mvan_3077 86 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120404495 Common murG N-acetylglucosaminyl transferase Mvan_3523 208 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 120402416 Common - hypothetical protein Mvan_1405 2 None None None 120401100 Common - AAA ATPase, central domain protein Mvan_0072 89 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 120401042 Common - Betaine-aldehyde dehydrogenase Mvan_0014 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 120404885 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mvan_3931 142 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 120405173 Common - enoyl-CoA hydratase Mvan_4219 181 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120406855 Common - lycopene cyclase family protein Mvan_5914 10 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 120402511 Common - hypothetical protein Mvan_1502 27 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 120403098 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase Mvan_2106 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 120403552 Common - acyl-CoA thioesterase II Mvan_2565 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 120406091 Common - NAD-dependent epimerase/dehydratase Mvan_5143 134 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 120401076 Common - hypothetical protein Mvan_0048 1 None None None 120401998 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase Mvan_0983 213 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 120405268 Common - L-carnitine dehydratase/bile acid-inducible protein F Mvan_4314 112 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 120405187 Common - amidohydrolase 2 Mvan_4233 12 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 120405440 Common - MgtE intracellular region Mvan_4488 163 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 120403515 Common - hypothetical protein Mvan_2527 4 None None None 120403854 Common - hypothetical protein Mvan_2871 4 None None None 120401430 Common - hypothetical protein Mvan_0405 13 COG1647 COG1647, Esterase/lipase General function prediction only 120406056 Common - 4-amino-4-deoxychorismate lyase Mvan_5108 110 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 120404198 Common - protein tyrosine phosphatase Mvan_3220 97 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 120405186 Common - peptidase M24 Mvan_4232 188 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 120406905 Nonpathogen - hypothetical protein Mvan_5971 1 None None None 120402263 Common - ROK family protein Mvan_1251 129 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 120405536 Common - short-chain dehydrogenase/reductase SDR Mvan_4584 150 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 120403906 Common - tryptophan synthase subunit beta Mvan_2923 224 COG1350 COG1350, Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB) General function prediction only 120403833 Common - protein of unknown function DUF140 Mvan_2849 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 120401122 Common - PTS system, fructose subfamily, IIC subunit Mvan_0094 137 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 120404144 Common - hypothetical protein Mvan_3165 58 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 120406762 Common - hypothetical protein Mvan_5820 1 None None None 120405097 Common - hypothetical protein Mvan_4143 1 None None None 120405104 Common - virulence factor Mce family protein Mvan_4150 7 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120402246 Common nusG transcription antitermination protein NusG Mvan_1234 215 COG0250 NusG, Transcription antiterminator Transcription 120404628 Common - ABC transporter-related protein Mvan_3664 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 120403874 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mvan_2891 27 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 120406775 Common - hypothetical protein Mvan_5833 6 None None None 120405247 Common - Mov34/MPN/PAD-1 family protein Mvan_4293 31 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 120404447 Common - protein of unknown function DUF75 Mvan_3475 22 COG2047 COG2047, Uncharacterized protein (ATP-grasp superfamily) General function prediction only 120401614 Common - UDP-glucose 6-dehydrogenase Mvan_0598 206 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 120402980 Common - Enoyl-CoA hydratase/isomerase Mvan_1984 179 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120406530 Common - transcriptional regulator, DeoR family Mvan_5588 115 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 120403342 Common - peptidase M16 domain protein Mvan_2351 184 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 120401090 Common - Pirin domain protein domain protein Mvan_0062 145 COG1741 COG1741, Pirin-related protein General function prediction only 120404806 Common - Thioesterase Mvan_3848 42 COG3208 GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 120401849 Common - hypothetical protein Mvan_0834 2 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 120401170 Common - hypothetical protein Mvan_0142 2 None None None 120404789 Common - hypothetical protein Mvan_3831 49 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 120401426 Common - cytochrome P450 Mvan_0401 78 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120404440 Common - mercuric reductase Mvan_3468 241 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 120405578 Common - hypothetical protein Mvan_4626 4 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 120402944 Common - protein of unknown function DUF190 Mvan_1947 19 COG1993 COG1993, Uncharacterized conserved protein Function unknown 120404967 Common - bifunctional deaminase-reductase domain protein Mvan_4013 32 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 120402508 Common - hypothetical protein Mvan_1499 1 None None None 120403858 Common - acyl-CoA dehydrogenase domain protein Mvan_2875 25 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120403968 Common - acyltransferase 3 Mvan_2986 99 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 120405466 Common - ABC transporter-related protein Mvan_4514 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 120402966 Common - MaoC domain protein dehydratase Mvan_1970 68 COG2030 MaoC, Acyl dehydratase Lipid metabolism 120405708 Nonpathogen - hypothetical protein Mvan_4758 1 None None None 120405160 Common - acetyl-CoA acetyltransferases Mvan_4206 187 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120401539 Common - virulence factor Mce family protein Mvan_0518 14 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120403734 Common - hypothetical protein Mvan_2750 88 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 120403296 Common - uroporphyrin-III C-methyltransferase Mvan_2305 204 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 120403670 Common - LemA family protein Mvan_2686 130 COG1704 LemA, Uncharacterized conserved protein Function unknown 120403394 Common - hypothetical protein Mvan_2403 3 None None None 120405636 Common - cysteine dioxygenase type I Mvan_4684 9 None None None 120402587 Common - amine oxidase Mvan_1580 20 COG3349 COG3349, Uncharacterized conserved protein Function unknown 120403274 Common - regulatory protein, ArsR Mvan_2283 60 COG0640 ArsR, Predicted transcriptional regulators Transcription 120405416 Common - FAD linked oxidase domain protein Mvan_4464 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 120406923 Nonpathogen - hypothetical protein Mvan_5990 3 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 120405499 Common - major facilitator superfamily MFS_1 Mvan_4547 116 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 120406367 Common - Tn554 transposase C Mvan_5420 5 None None None 120401684 Common - Alcohol dehydrogenase GroES domain protein Mvan_0669 202 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 120402236 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Mvan_1224 197 COG0388 COG0388, Predicted amidohydrolase General function prediction only 120405250 Common clpS ATP-dependent Clp protease adaptor protein ClpS Mvan_4296 16 COG2127 COG2127, Uncharacterized conserved protein Function unknown 120406182 Common - 4-hydroxy-2-ketovalerate aldolase Mvan_5234 194 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 120405395 Common - molydopterin dinucleotide-binding region Mvan_4442 180 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 120404183 Common - glycosyl transferase, group 1 Mvan_3205 186 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 120403918 Common - hypothetical protein Mvan_2935 1 None None None 120406222 Common - L-2,4-diaminobutyric acid acetyltransferase Mvan_5274 29 COG3818 COG3818, Predicted acetyltransferase, GNAT superfamily General function prediction only 120402790 Common - DEAD/DEAH box helicase domain protein Mvan_1791 241 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 120401748 Common - transcriptional regulator, Fis family Mvan_0733 16 None None None 120405786 Common - SAF domain Mvan_4836 12 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 120403938 Nonpathogen - hypothetical protein Mvan_2955 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 120404692 Nonpathogen - hypothetical protein Mvan_3733 1 None None None 120402518 Common - hypothetical protein Mvan_1509 4 COG3889 COG3889, Predicted solute binding protein General function prediction only 120403181 Common rimM 16S rRNA-processing protein Mvan_2189 181 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 120404430 Common - Vesicle-fusing ATPase Mvan_3458 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 120405050 Common - putative conserved proline rich membrane protein Mvan_4096 1 None None None 120402185 Common - hypothetical protein Mvan_1173 7 None None None 120401974 Common - Mammalian cell entry related domain protein Mvan_0959 6 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120402566 Common - transcriptional regulator, MarR family Mvan_1559 105 COG1846 MarR, Transcriptional regulators Transcription 120406470 Common recR recombination protein RecR Mvan_5527 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 120406039 Common - phosphate ABC transporter, inner membrane subunit PstC Mvan_5091 222 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 120405079 Common - MaoC domain protein dehydratase Mvan_4125 210 COG4982 COG4982, 3-oxoacyl- acyl-carrier protein 120405398 Common - D-tyrosyl-tRNA deacylase Mvan_4446 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 120401732 Common - uracil-xanthine permease Mvan_0717 120 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 120404307 Common - hypothetical protein Mvan_3333 2 None None None 120401044 Common - hypothetical protein Mvan_0016 1 None None None 120405812 Nonpathogen - glycosyl transferase, family 39 Mvan_4862 4 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 120406661 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Mvan_5719 11 None None None 120406547 Common - short-chain dehydrogenase/reductase SDR Mvan_5605 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120401261 Common - Arylamine N-acetyltransferase Mvan_0235 45 COG2162 NhoA, Arylamine N-acetyltransferase Secondary metabolites biosynthesis, transport, and catabolism 120401801 Nonpathogen - ribosomal protein L12 Mvan_0786 1 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 120406494 Common - protein of unknown function DUF125, transmembrane Mvan_5552 65 COG1814 COG1814, Uncharacterized membrane protein Function unknown 120404531 Common - Cytochrome b/b6, N-terminal domain Mvan_3560 148 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 120402484 Nonpathogen - hypothetical protein Mvan_1475 1 None None None 120404751 Common - protein of unknown function DUF427 Mvan_3793 42 COG2343 COG2343, Uncharacterized protein conserved in bacteria Function unknown 120402778 Common - hypothetical protein Mvan_1779 10 None None None 120405962 Nonpathogen - hypothetical protein Mvan_5013 1 None None None 120403069 Common - molybdopterin dehydrogenase, FAD-binding Mvan_2077 67 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 120401432 Common - transposase IS116/IS110/IS902 family protein Mvan_0407 30 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 120401496 Common - dihydrodipicolinate synthetase Mvan_0472 233 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 120406137 Common - short chain dehydrogenase Mvan_5189 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120401271 Common - cytochrome P450 Mvan_0245 84 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120403600 Common aspS aspartyl-tRNA synthetase Mvan_2615 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 120403646 Common - putative export or membrane protein Mvan_2662 9 None None None 120402774 Common - hypothetical protein Mvan_1775 16 COG3361 COG3361, Uncharacterized conserved protein Function unknown 120405070 Common - Hydrogen dehydrogenase Mvan_4116 166 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 120406876 Common - phage integrase family protein Mvan_5937 220 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 120405942 Common - carboxyl transferase Mvan_4993 204 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 120405523 Common - Methyltransferase type 12 Mvan_4571 44 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 120406512 Common - microcompartments protein Mvan_5570 46 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 120403579 Common - inner-membrane translocator Mvan_2594 88 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 120404841 Common - ABC transporter-related protein Mvan_3884 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 120406735 Common - cutinase Mvan_5793 4 None None None 120405076 Common - hypothetical protein Mvan_4122 166 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 120406154 Common - acyl-CoA dehydrogenase domain protein Mvan_5206 150 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120402506 Nonpathogen - hypothetical protein Mvan_1497 1 None None None 120402374 Nonpathogen - LigA Mvan_1363 1 None None None 120405100 Common - virulence factor Mce family protein Mvan_4146 11 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120406375 Common - protein of unknown function DUF1469 Mvan_5428 13 COG5393 COG5393, Predicted membrane protein Function unknown 120401965 Common - hypothetical protein Mvan_0950 1 None None None 120405547 Common - Carotenoid oxygenase Mvan_4595 36 COG3670 COG3670, Lignostilbene-alpha,beta-dioxygenase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 120404079 Common - Alkane 1-monooxygenase Mvan_3100 26 COG3239 DesA, Fatty acid desaturase Lipid metabolism 120405906 Common - acyl-CoA dehydrogenase domain protein Mvan_4957 16 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120403057 Nonpathogen - hypothetical protein Mvan_2063 1 None None None 120403311 Common - enoyl-CoA hydratase Mvan_2320 182 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120406021 Common - cyclase/dehydrase Mvan_5073 8 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 120405413 Common - H+ Antiporter protein Mvan_4461 21 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120401397 Common - transcriptional regulator, TetR family Mvan_0372 13 COG1309 AcrR, Transcriptional regulator Transcription 120404072 Common - extracellular solute-binding protein, family 1 Mvan_3093 127 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 120406760 Common - DEAD/DEAH box helicase domain protein Mvan_5818 124 COG4581 COG4581, Superfamily II RNA helicase DNA replication, recombination, and repair 120404502 Common - FHA domain containing protein Mvan_3530 1 None None None 120404837 Common - LppR Mvan_3879 1 None None None 120404339 Common - protein of unknown function DUF35 Mvan_3365 8 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 120403763 Nonpathogen - hypothetical protein Mvan_2779 2 None None None 120404644 Common - hypothetical protein Mvan_3680 17 None None None 120406818 Common - phosphonate ABC transporter, ATPase subunit Mvan_5876 249 COG3638 COG3638, ABC-type phosphate/phosphonate transport system, ATPase component Inorganic ion transport and metabolism 120406811 Common - ABC transporter-related protein Mvan_5869 249 COG4107 PhnK, ABC-type phosphonate transport system, ATPase component Inorganic ion transport and metabolism 120401555 Common - 3-phenylpropionate dioxygenase subunit beta Mvan_0534 25 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 120403673 Common - ribulose-phosphate 3-epimerase Mvan_2689 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 120406309 Common - hypothetical protein Mvan_5361 50 COG3616 COG3616, Predicted amino acid aldolase or racemase Amino acid transport and metabolism 120404708 Common - Redoxin domain protein Mvan_3749 207 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 120404211 Nonpathogen - hypothetical protein Mvan_3233 1 None None None 120402727 Common - dTDP-4-dehydrorhamnose reductase Mvan_1727 164 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 120403203 Common - RNA-directed DNA polymerase Mvan_2212 96 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 120404188 Common - hypothetical protein Mvan_3210 7 None None None 120405152 Common - luciferase family protein Mvan_4198 25 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120406125 Common - HNH endonuclease Mvan_5177 3 None None None 120405626 Common - cystathionine beta-synthase Mvan_4674 221 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 120403208 Common - amino acid permease-associated region Mvan_2217 83 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 120405322 Nonpathogen - hypothetical protein Mvan_4368 5 None None None 120406271 Common - hypothetical protein Mvan_5323 16 None None None 120406253 Common - flavin reductase domain protein, FMN-binding Mvan_5305 128 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 120405808 Common - hypothetical protein Mvan_4858 4 None None None 120403562 Common - protein of unknown function DUF1304 Mvan_2576 22 COG3759 COG3759, Predicted membrane protein Function unknown 120402225 Common - nitroreductase Mvan_1213 88 COG0778 NfnB, Nitroreductase Energy production and conversion 120401903 Common - Methyltransferase type 12 Mvan_0888 11 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 120405388 Common - hypothetical protein Mvan_4435 21 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 120401367 Common - protein of unknown function DUF1446 Mvan_0342 35 None None None 120402613 Common - phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I Mvan_1607 174 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 120405794 Common - two component transcriptional regulator, winged helix family Mvan_4844 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 120401972 Common - protein of unknown function DUF140 Mvan_0957 148 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 120404689 Common - heavy metal translocating P-type ATPase Mvan_3729 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 120406441 Common - transposase, mutator type Mvan_5496 80 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 120405462 Common - acyl-CoA synthetase Mvan_4510 201 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120403400 Common - hydrogenase maturation protease Mvan_2409 22 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 120403596 Common - DGPFAETKE family protein Mvan_2611 31 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 120405992 Common - putative glutathione S-transferase Mvan_5043 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 120402543 Nonpathogen - hypothetical protein Mvan_1535 1 None None None 120406290 Common - DNA repair protein RadA Mvan_5342 211 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 120404310 Common - Tetratricopeptide TPR_4 Mvan_3336 2 None None None 120403696 Common - Alpha/beta hydrolase fold-3 domain protein Mvan_2712 100 COG0657 Aes, Esterase/lipase Lipid metabolism 120401344 Common - luciferase family protein Mvan_0319 39 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120403388 Common - transcriptional regulator, XRE family Mvan_2397 24 COG1396 HipB, Predicted transcriptional regulators Transcription 120401335 Nonpathogen - hypothetical protein Mvan_0309 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 120403073 Common - periplasmic binding protein Mvan_2081 51 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 120404567 Common - glutamine synthetase, type I Mvan_3598 227 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 120404194 Common - type I phosphodiesterase/nucleotide pyrophosphatase Mvan_3216 16 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 120406477 Common - DNA polymerase III subunits gamma and tau Mvan_5534 248 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 120406003 Common - hypothetical protein Mvan_5054 15 COG2378 COG2378, Predicted transcriptional regulator Transcription 120406481 Common - dihydrodipicolinate reductase Mvan_5538 23 COG3804 COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase Function unknown 120406822 Common - putative esterase Mvan_5880 7 COG0627 COG0627, Predicted esterase General function prediction only 120402822 Common - hypothetical protein Mvan_1823 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 120401106 Nonpathogen - 10 kDa culture filtrate antigen LHP (CFP10) Mvan_0078 1 None None None 120402407 Common - transcriptional regulator, TetR family Mvan_1396 5 COG1309 AcrR, Transcriptional regulator Transcription 120404173 Common - Acyl-CoA dehydrogenase, type 2, C-terminal domain Mvan_3194 36 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120401777 Common - short chain dehydrogenase Mvan_0762 136 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120405284 Common - F0F1 ATP synthase subunit alpha Mvan_4330 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 120403438 Common - soluble pyridine nucleotide transhydrogenase Mvan_2448 241 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 120401410 Common - periplasmic binding protein/LacI transcriptional regulator Mvan_0385 126 COG1609 PurR, Transcriptional regulators Transcription 120401677 Common - hypothetical protein Mvan_0662 1 None None None 120403597 Common - putative RNA polymerase, sigma-24 subunit, ECF subfamily Mvan_2612 41 COG4941 COG4941, Predicted RNA polymerase sigma factor containing a TPR repeat domain Transcription 120401390 Common - virulence factor Mce family protein Mvan_0365 22 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120405452 Common - putative ABC transporter membrane-spanning protein Mvan_4500 15 COG3559 TnrB3, Putative exporter of polyketide antibiotics Cell envelope biogenesis, outer membrane 120406112 Common - Alcohol dehydrogenase GroES domain protein Mvan_5164 159 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 120404734 Common - binding-protein-dependent transport systems inner membrane component Mvan_3775 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 120406954 Common - ABC transporter-related protein Mvan_6023 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 120404133 Common - polysaccharide deacetylase Mvan_3154 50 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 120402711 Common - PilT protein domain protein Mvan_1710 50 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 120401206 Common - hypothetical protein Mvan_0178 5 None None None 120405892 Common - heat shock protein Hsp20 Mvan_4943 154 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 120402146 Common - hypothetical protein Mvan_1133 37 COG4913 COG4913, Uncharacterized protein conserved in bacteria Function unknown 120402019 Common - ABC transporter-related protein Mvan_1004 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 120404243 Common - transcriptional regulator, XRE family Mvan_3268 11 COG1396 HipB, Predicted transcriptional regulators Transcription 120404595 Common - hypothetical protein Mvan_3627 11 COG5615 COG5615, Predicted integral membrane protein Function unknown 120401181 Common - hypothetical protein Mvan_0153 2 None None None 120405675 Common - peptidase M15D, vanX D-ala-D-ala dipeptidase Mvan_4724 43 COG2173 DdpX, D-alanyl-D-alanine dipeptidase Cell envelope biogenesis, outer membrane 120402239 Common - hypothetical protein Mvan_1227 8 COG3673 COG3673, Uncharacterized conserved protein Function unknown 120402313 Common - cytochrome P450 Mvan_1302 80 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120404354 Common - Siderophore-interacting protein Mvan_3380 57 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 120404861 Common - putative signal-transduction protein with CBS domains Mvan_3907 156 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 120405739 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Mvan_4789 39 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 120402136 Common - DSBA oxidoreductase Mvan_1123 17 COG3917 NahD, 2-hydroxychromene-2-carboxylate isomerase Secondary metabolites biosynthesis, transport, and catabolism 120402876 Common - NADH dehydrogenase subunit H Mvan_1878 191 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 120403570 Common - extracellular solute-binding protein, family 5 Mvan_2585 13 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 120403301 Common - hypothetical protein Mvan_2310 1 None None None 120403197 Common - FMN-dependent alpha-hydroxy acid dehydrogenase Mvan_2206 110 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 120405404 Common - putative adenylate/guanylate cyclase Mvan_4452 33 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 120403031 Common - DNA polymerase IV Mvan_2037 184 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 120401085 Common - hypothetical protein Mvan_0057 10 None None None 120402955 Common - coenzyme F390 synthetase-like Mvan_1959 12 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 120405936 Common - hypothetical protein Mvan_4987 5 None None None 120405115 Common - hypothetical protein Mvan_4161 1 None None None 120401316 Common - Acetamidase/Formamidase Mvan_0290 66 COG2421 COG2421, Predicted acetamidase/formamidase Energy production and conversion 120406435 Common rpmB 50S ribosomal protein L28 Mvan_5489 156 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 120404319 Common - small multidrug resistance protein Mvan_3345 2 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 120402079 Common - hypothetical protein Mvan_1064 1 None None None 120402541 Common - tRNA/rRNA methyltransferase (SpoU) Mvan_1533 156 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 120404819 Common - protein of unknown function DUF21 Mvan_3861 158 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 120403618 Common - short-chain dehydrogenase/reductase SDR Mvan_2633 151 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 120401126 Common - hypothetical protein Mvan_0098 1 None None None 120402608 Common - Creatininase Mvan_1602 75 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 120406264 Common - permease Mvan_5316 95 COG0701 COG0701, Predicted permeases General function prediction only 120402363 Common - thiamine pyrophosphate enzyme domain protein TPP-binding Mvan_1352 216 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 120406192 Common - hypothetical protein Mvan_5244 3 None None None 120401791 Common - ABC transporter-related protein Mvan_0776 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 120405263 Common - putative adenylate/guanylate cyclase Mvan_4309 65 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 120402760 Common - sigma 54 modulation protein/ribosomal protein S30EA Mvan_1761 84 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 120402807 Nonpathogen - hypothetical protein Mvan_1808 1 None None None 120401739 Common - phosphomethylpyrimidine kinase Mvan_0724 213 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 120402609 Common - Glutamate--ammonia ligase Mvan_1603 225 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 120404018 Common - Activator of Hsp90 ATPase 1 family protein Mvan_3038 20 COG3832 COG3832, Uncharacterized conserved protein Function unknown 120404139 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Mvan_3160 129 COG0388 COG0388, Predicted amidohydrolase General function prediction only 120405033 Nonpathogen - hypothetical protein Mvan_4079 2 None None None 120406158 Common - 3-ketosteroid-delta-1-dehydrogenase Mvan_5210 54 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 120402937 Common - hypothetical protein Mvan_1940 10 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 120403781 Common - NUDIX hydrolase Mvan_2797 69 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 120402612 Common - glucose-methanol-choline oxidoreductase Mvan_1606 90 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 120404953 Common - short-chain dehydrogenase/reductase SDR Mvan_3999 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120401473 Nonpathogen - hypothetical protein Mvan_0448 1 None None None 120405433 Common - Malate dehydrogenase (oxaloacetate-decarboxylating) Mvan_4481 196 COG0281 SfcA, Malic enzyme Energy production and conversion 120405632 Common - enoyl-CoA hydratase Mvan_4680 168 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120401756 Common - putative monovalent cation/H+ antiporter subunit E Mvan_0741 8 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 120406695 Common - Rhomboid family protein Mvan_5753 166 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 120406930 Nonpathogen - hypothetical protein Mvan_5998 1 None None None 120403719 Common - FeS assembly ATPase SufC Mvan_2735 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 120406388 Common - transcription factor WhiB Mvan_5441 19 None None None 120403958 Common - uracil phosphoribosyltransferase Mvan_2976 166 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 120402478 Common rplM 50S ribosomal protein L13 Mvan_1469 226 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 120403210 Common - alkylhydroperoxidase-like protein, AhpD family Mvan_2219 70 COG2128 COG2128, Uncharacterized conserved protein Function unknown 120401380 Common - protein of unknown function DUF1486 Mvan_0355 2 None None None 120406540 Common - binding-protein-dependent transport systems inner membrane component Mvan_5598 132 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 120404446 Common metH B12-dependent methionine synthase Mvan_3474 178 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 120406364 Common - protein of unknown function DUF955 Mvan_5417 20 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 120404043 Common - ATP-dependent protease La Mvan_3064 209 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 120401810 Common - hypothetical protein Mvan_0795 1 None None None 120406142 Common - NAD-dependent epimerase/dehydratase Mvan_5194 42 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 120402584 Common - Polyprenyl synthetase Mvan_1577 234 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 120403252 Common - peptidase M50 Mvan_2261 213 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 120405196 Common - luciferase family protein Mvan_4242 131 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120401726 Common - hypothetical protein Mvan_0711 8 None None None 120401069 Common - PE-PPE, C-terminal domain protein Mvan_0041 1 None None None 120404851 Common - hypothetical protein Mvan_3895 22 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 120406998 Common - Peptidoglycan-binding domain 1 protein Mvan_6069 100 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 120404435 Common - putative RecB family exonuclease Mvan_3463 30 COG2887 COG2887, RecB family exonuclease DNA replication, recombination, and repair 120405518 Common - hypothetical protein Mvan_4566 4 None None None 120401362 Common - hypothetical protein Mvan_0337 14 None None None 120402499 Common - hypothetical protein Mvan_1490 11 None None None 120404543 Common cobS cobalamin synthase Mvan_3572 20 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 120406939 Nonpathogen - Tetratricopeptide TPR_2 repeat protein Mvan_6007 1 None None None 120401590 Common - AAA ATPase Mvan_0572 60 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 120401844 Common - phosphoglycerate mutase 1 family Mvan_0829 137 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 120406318 Common - dihydropteroate synthase Mvan_5370 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 120401704 Common - hypothetical protein Mvan_0689 1 None None None 120401355 Common - hypothetical protein Mvan_0330 10 COG1846 MarR, Transcriptional regulators Transcription 120402628 Common - death-on-curing family protein Mvan_1622 29 COG3654 Doc, Prophage maintenance system killer protein General function prediction only 120401455 Common - phosphoesterase, PA-phosphatase related Mvan_0430 15 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 120406170 Common - acetyl-CoA acetyltransferase Mvan_5222 90 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120402302 Common - protein of unknown function DUF222 Mvan_1291 5 None None None 120402813 Common - hypothetical protein Mvan_1814 48 COG1615 COG1615, Uncharacterized conserved protein Function unknown 120404889 Common - Ribokinase Mvan_3935 113 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 120403091 Common - electron transfer flavoprotein beta-subunit Mvan_2099 153 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 120404383 Common - hypothetical protein Mvan_3410 7 None None None 120403959 Common - isocitrate lyase Mvan_2977 124 COG2224 AceA, Isocitrate lyase Energy production and conversion 120403525 Common - NifC-like ABC-type porter Mvan_2537 178 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 120404782 Common - amidase Mvan_3824 217 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 120402072 Common - Transport protein Mvan_1057 53 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 120402769 Common - GTPase EngC Mvan_1770 164 COG1162 COG1162, Predicted GTPases General function prediction only 120403152 Common - hypothetical protein Mvan_2160 1 None None None 120401582 Common - 4-carboxymuconolactone decarboxylase Mvan_0563 123 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 120402400 Common - carbamate kinase Mvan_1389 73 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 120404880 Common - nicotinate (nicotinamide) nucleotide adenylyltransferase Mvan_3926 188 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 120405177 Common - protein of unknown function DUF227 Mvan_4223 11 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 120401710 Common - GCN5-related N-acetyltransferase Mvan_0695 33 COG0456 RimI, Acetyltransferases General function prediction only 120403813 Common - cytochrome d ubiquinol oxidase, subunit II Mvan_2829 156 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 120405617 Common - transcriptional regulator, Fis family Mvan_4665 105 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 120401424 Common - ferredoxin reductase Mvan_0399 6 COG1141 Fer, Ferredoxin Energy production and conversion 120405561 Common - alpha/beta hydrolase fold Mvan_4609 136 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120402836 Common - PE-PPE, C-terminal domain protein Mvan_1838 1 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 120404682 Common - hypothetical protein Mvan_3722 24 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 120402123 Common - hypothetical protein Mvan_1109 2 None None None 120401636 Common - response regulator receiver protein Mvan_0620 17 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 120405099 Common - virulence factor Mce family protein Mvan_4145 11 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120403882 Common - major facilitator superfamily MFS_1 Mvan_2899 163 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120402905 Common - histidinol-phosphate phosphatase, putative Mvan_1908 191 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 120404066 Common - transcriptional repressor, CopY family Mvan_3087 36 COG3682 COG3682, Predicted transcriptional regulator Transcription 120401953 Common - hypothetical protein Mvan_0938 7 None None None 120402783 Common - 3-dehydroquinate dehydratase, type II Mvan_1784 169 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 120402855 Common - acyl-CoA dehydrogenase domain protein Mvan_1857 156 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120403466 Common - Na+/H+ antiporter NhaA Mvan_2476 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 120406096 Common - putative transcriptional regulator, TetR family Mvan_5148 4 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 120402170 Common - Endoribonuclease L-PSP Mvan_1158 32 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 120401350 Common - short-chain dehydrogenase/reductase SDR Mvan_0325 233 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120403555 Common - transcriptional regulator, TetR family Mvan_2569 15 COG1309 AcrR, Transcriptional regulator Transcription 120405976 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mvan_5027 43 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 120404791 Common - Transport protein Mvan_3833 49 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 120403371 Common thyA thymidylate synthase Mvan_2380 136 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 120406637 Common - luciferase family protein Mvan_5695 74 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120404488 Common - hypothetical protein Mvan_3516 18 COG0762 COG0762, Predicted integral membrane protein Function unknown 120405356 Common - 3-oxoacid CoA-transferase, A subunit Mvan_4403 92 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 120401543 Common - aldehyde dehydrogenase Mvan_0522 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 120405304 Common argS arginyl-tRNA synthetase Mvan_4350 246 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 120401348 Common - transcriptional regulator, TetR family Mvan_0323 5 COG1309 AcrR, Transcriptional regulator Transcription 120403773 Common - 8-amino-7-oxononanoate synthase Mvan_2789 190 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 120405170 Common - hypothetical protein Mvan_4216 3 None None None 120402490 Common - anti-sigma-factor antagonist Mvan_1481 6 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 120405980 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Mvan_5031 203 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 120403356 Common - NADH ubiquinone oxidoreductase, 20 kDa subunit Mvan_2365 79 COG1740 HyaA, Ni,Fe-hydrogenase I small subunit Energy production and conversion 120405126 Common - hypothetical protein Mvan_4172 4 COG2267 PldB, Lysophospholipase Lipid metabolism 120405813 Common - glycosyl transferase, family 2 Mvan_4863 113 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 120401918 Common - Limonene-1,2-epoxide hydrolase Mvan_0903 7 COG4308 LimA, Limonene-1,2-epoxide hydrolase Secondary metabolites biosynthesis, transport, and catabolism 120405717 Common - hypothetical protein Mvan_4767 4 None None None 120401327 Common - bifunctional uroporphyrinogen-III synthetase/response regulator domain protein Mvan_0301 36 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 120402344 Common rplX 50S ribosomal protein L24 Mvan_1333 211 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 120402206 Common - FAD dependent oxidoreductase Mvan_1194 10 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 120405500 Common - NUDIX hydrolase Mvan_4548 146 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 120401062 Common - N-6 DNA methylase Mvan_0034 161 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 120404972 Common - Myo-inositol catabolism IolB domain protein Mvan_4018 51 COG3718 IolB, Uncharacterized enzyme involved in inositol metabolism Carbohydrate transport and metabolism 120401232 Common - luciferase family protein Mvan_0205 21 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120406801 Common - alpha/beta hydrolase fold Mvan_5859 7 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120402089 Nonpathogen - hypothetical protein Mvan_1074 1 None None None 120406833 Common - regulatory protein, ArsR Mvan_5891 75 COG0640 ArsR, Predicted transcriptional regulators Transcription 120405732 Common - UDP-N-acetylglucosamine pyrophosphorylase Mvan_4782 229 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 120402575 Common - Strictosidine synthase Mvan_1568 41 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 120402696 Common - transposase IS3/IS911 family protein Mvan_1691 56 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 120403788 Common hisD histidinol dehydrogenase Mvan_2804 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 120406754 Common - short-chain dehydrogenase/reductase SDR Mvan_5812 164 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120403727 Common - hypothetical protein Mvan_2743 11 None None None 120404323 Common - major facilitator superfamily MFS_1 Mvan_3349 165 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120401529 Common - hypothetical protein Mvan_0507 3 COG3462 COG3462, Predicted membrane protein Function unknown 120402597 Common deoA thymidine phosphorylase Mvan_1591 120 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 120406333 Common - Integral membrane protein TerC Mvan_5385 99 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 120402976 Common - AMP-dependent synthetase and ligase Mvan_1980 216 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120404342 Common - luciferase family protein Mvan_3368 40 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120405999 Common - molybdopterin biosynthesis MoaE Mvan_5050 36 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 120402352 Common rplO 50S ribosomal protein L15 Mvan_1341 201 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 120403940 Common - hypothetical protein Mvan_2957 1 None None None 120401110 Common - hypothetical protein Mvan_0082 1 None None None 120401829 Common - Arginase/agmatinase/formiminoglutamase Mvan_0814 157 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 120403415 Common - polar amino acid ABC transporter, inner membrane subunit Mvan_2425 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 120405163 Common - short-chain dehydrogenase/reductase SDR Mvan_4209 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120405694 Common - hypothetical protein Mvan_4744 1 None None None 120405065 Common - protein of unknown function DUF140 Mvan_4111 150 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 120405864 Common - NAD-dependent epimerase/dehydratase Mvan_4914 174 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 120407003 Common - single-stranded nucleic acid binding R3H domain protein Mvan_6074 70 COG1847 Jag, Predicted RNA-binding protein General function prediction only 120405132 Common - protein of unknown function DUF1330 Mvan_4178 10 COG5470 COG5470, Uncharacterized conserved protein Function unknown 120402082 Common - peptidase S15 Mvan_1067 19 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 120401417 Common - Xanthine/uracil/vitamin C permease Mvan_0392 135 COG2252 COG2252, Permeases General function prediction only 120401887 Common - hypothetical protein Mvan_0872 4 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 120402921 Common - cutinase Mvan_1924 3 None None None 120402637 Common - DNA-formamidopyrimidine glycosylase Mvan_1631 178 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 120403332 Common - short chain dehydrogenase Mvan_2341 231 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120401589 Common - Integrase, catalytic region Mvan_0571 49 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 120403190 Common - acyl-CoA thioesterase Mvan_2198 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 120404453 Common - hypothetical protein Mvan_3481 17 None None None 120402321 Common - ribosomal protein L22 Mvan_1310 212 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 120406917 Nonpathogen - hypothetical protein Mvan_5984 1 None None None 120404278 Common - hypothetical protein Mvan_3303 5 None None None 120406451 Common - ammonium transporter Mvan_5508 197 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 120402027 Common - short-chain dehydrogenase/reductase SDR Mvan_1012 217 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 120405540 Common - Enoyl-CoA hydratase/isomerase Mvan_4588 178 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120404996 Nonpathogen - hypothetical protein Mvan_4042 1 None None None 120404336 Common - transcriptional regulator, LysR family Mvan_3362 185 COG0583 LysR, Transcriptional regulator Transcription 120404777 Common - regulatory protein, ArsR Mvan_3819 162 COG0640 ArsR, Predicted transcriptional regulators Transcription 120401152 Nonpathogen - hypothetical protein Mvan_0124 1 None None None 120401643 Common - hypothetical protein Mvan_0627 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 120402950 Common - transposase IS3/IS911 family protein Mvan_1954 56 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 120403607 Common - binding-protein-dependent transport systems inner membrane component Mvan_2622 152 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 120406757 Nonpathogen - aminoglycoside phosphotransferase Mvan_5815 3 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 120404988 Common - glycosyltransferase, MGT family Mvan_4034 52 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 120406380 Common - endonuclease III Mvan_5433 238 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 120405046 Common - transcriptional regulator, TetR family Mvan_4092 18 COG1309 AcrR, Transcriptional regulator Transcription 120401650 Common - chaperone protein DnaK Mvan_0634 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 120403102 Common - AMP-dependent synthetase and ligase Mvan_2110 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120401401 Common - precorrin 6A synthase Mvan_0376 25 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 120403000 Common - short-chain dehydrogenase/reductase SDR Mvan_2006 233 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120406519 Common - ABC transporter-related protein Mvan_5577 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 120405146 Nonpathogen - hypothetical protein Mvan_4192 1 None None None 120404725 Common - response regulator receiver protein Mvan_3766 129 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 120404758 Nonpathogen - hypothetical protein Mvan_3800 1 None None None 120401717 Common - anti-sigma-factor antagonist Mvan_0702 1 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 120406553 Common - putative aminotransferase Mvan_5611 241 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 120404753 Common - MscS Mechanosensitive ion channel Mvan_3795 198 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 120402386 Common - ATPase, P-type (transporting), HAD superfamily, subfamily IC Mvan_1375 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 120404370 Common - Carboxymuconolactone decarboxylase Mvan_3396 45 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 120406778 Common - putative methyltransferase Mvan_5836 22 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 120401165 Common - virulence factor Mce family protein Mvan_0137 8 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120403066 Common - transposase, IS4 family protein Mvan_2074 26 None None None 120402829 Common - beta-lactamase domain protein Mvan_1830 199 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 120404088 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mvan_3109 83 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 120405200 Common - alpha/beta hydrolase fold Mvan_4246 175 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120406675 Common - binding-protein-dependent transport systems inner membrane component Mvan_5733 143 COG4132 COG4132, ABC-type uncharacterized transport system, permease component General function prediction only 120402664 Nonpathogen - hypothetical protein Mvan_1658 1 None None None 120406027 Common - transcriptional regulator, TetR family Mvan_5079 14 COG1309 AcrR, Transcriptional regulator Transcription 120406620 Nonpathogen - hypothetical protein Mvan_5678 1 None None None 120406168 Common - protein of unknown function DUF35 Mvan_5220 20 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 120403934 Common - RNA-binding S4 domain protein Mvan_2951 102 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 120403864 Common - NADH:flavin oxidoreductase/NADH oxidase Mvan_2881 179 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 120401444 Common - putative DNA-binding protein Mvan_0419 3 None None None 120405668 Common - hypothetical protein Mvan_4717 6 None None None 120404081 Common - PE-PPE, C-terminal domain protein Mvan_3102 1 COG4547 CobT, Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase) Coenzyme metabolism 120401851 Common - hypothetical protein Mvan_0836 7 None None None 120404581 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mvan_3613 45 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 120403657 Common - Xylose isomerase domain protein TIM barrel Mvan_2673 31 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 120401915 Common - acetyl-CoA acetyltransferase Mvan_0900 98 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120406580 Nonpathogen - hypothetical protein Mvan_5638 2 None None None 120404008 Common - hypothetical protein Mvan_3028 7 None None None 120406629 Common - hypothetical protein Mvan_5687 78 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 120404516 Common - phospholipid/glycerol acyltransferase Mvan_3544 161 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 120406324 Common - molydopterin dinucleotide-binding region Mvan_5376 180 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 120401820 Common - transcriptional regulator, TetR family Mvan_0805 16 COG1309 AcrR, Transcriptional regulator Transcription 120402897 Common - Acyl-CoA dehydrogenase, type 2, C-terminal domain Mvan_1900 46 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120403794 Common - imidazole glycerol phosphate synthase subunit HisF Mvan_2810 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 120406058 Common - hypothetical protein Mvan_5110 16 None None None 120401803 Common - Alcohol dehydrogenase GroES domain protein Mvan_0788 204 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 120402824 Common - purine catabolism PurC domain protein Mvan_1825 16 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 120406571 Common - putative conserved transmembrane protein Mvan_5629 5 None None None 120406162 Common - 2-nitropropane dioxygenase, NPD Mvan_5214 124 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 120404406 Common - precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit Mvan_3434 92 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 120404710 Common - hypothetical protein Mvan_3751 2 None None None 120405762 Common - hypothetical protein Mvan_4812 40 COG3145 AlkB, Alkylated DNA repair protein DNA replication, recombination, and repair 120405619 Common - LmbE family protein Mvan_4667 40 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 120401452 Common - NAD-dependent epimerase/dehydratase Mvan_0427 108 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 120401819 Common - protein of unknown function DUF344 Mvan_0804 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 120402561 Common - O-acetylhomoserine aminocarboxypropyltransferase Mvan_1554 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 120403142 Common - putative transcriptional regulator, AsnC family Mvan_2150 29 COG1522 Lrp, Transcriptional regulators Transcription 120401422 Common - acyl-CoA synthetase Mvan_0397 221 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120406093 Common - adenylosuccinate lyase Mvan_5145 191 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 120406100 Common - transcriptional regulator, TetR family Mvan_5152 4 COG1309 AcrR, Transcriptional regulator Transcription 120402592 Common sdhB succinate dehydrogenase iron-sulfur subunit Mvan_1586 208 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 120404923 Common - Xylose isomerase domain protein TIM barrel Mvan_3969 61 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 120402164 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) Mvan_1152 178 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 120406987 Common - major facilitator superfamily MFS_1 Mvan_6058 60 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 120406417 Common - hypothetical protein Mvan_5470 20 None None None 120402900 Common - Alcohol dehydrogenase, zinc-binding domain protein Mvan_1903 87 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 120406781 Common - General substrate transporter Mvan_5839 165 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 120404216 Common - hypothetical protein Mvan_3239 18 None None None 120405528 Common - 2-nitropropane dioxygenase, NPD Mvan_4576 106 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 120405595 Common - short-chain dehydrogenase/reductase SDR Mvan_4643 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120402745 Common - transcriptional regulator, TetR family Mvan_1745 7 COG1309 AcrR, Transcriptional regulator Transcription 120402923 Common - NAD-dependent epimerase/dehydratase Mvan_1926 35 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 120405209 Common - acyl-CoA dehydrogenase domain protein Mvan_4255 87 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120403177 Common - hypothetical protein Mvan_2185 11 None None None 120402859 Common - short-chain dehydrogenase/reductase SDR Mvan_1861 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120406126 Common - trehalose synthase Mvan_5178 8 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 120406337 Common - UDP-glucose 4-epimerase Mvan_5389 231 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 120405775 Common - regulatory protein, ArsR Mvan_4825 90 COG0640 ArsR, Predicted transcriptional regulators Transcription 120406345 Common - hypothetical protein Mvan_5397 4 None None None 120402007 Common - Trans-hexaprenyltranstransferase Mvan_0992 242 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 120404804 Common - acyl transferase domain protein Mvan_3846 66 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 120403139 Common - phage integrase family protein Mvan_2147 218 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 120403118 Common - flavodoxin/nitric oxide synthase Mvan_2126 107 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 120404719 Common - transcriptional regulator, TetR family Mvan_3760 14 COG1309 AcrR, Transcriptional regulator Transcription 120401983 Common - hypothetical protein Mvan_0968 3 COG3662 COG3662, Uncharacterized protein conserved in bacteria Function unknown 120404941 Common - hypothetical protein Mvan_3987 29 None None None 120406593 Common - exported repetitive protein precursor PirG (cell surface protein) (EXP53) Mvan_5651 1 None None None 120401644 Nonpathogen - hypothetical protein Mvan_0628 1 None None None 120404032 Common - isochorismatase hydrolase Mvan_3053 127 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 120404432 Common - putative conserved lipoprotein LppK Mvan_3460 1 None None None 120406929 Common - hypothetical protein Mvan_5997 13 COG3864 COG3864, Uncharacterized protein conserved in bacteria Function unknown 120404588 Common - protein of unknown function DUF34 Mvan_3620 82 COG3323 COG3323, Uncharacterized protein conserved in bacteria Function unknown 120405010 Common - DsbA oxidoreductase Mvan_4056 16 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 120405022 Common - hypothetical protein Mvan_4068 20 COG0824 FcbC, Predicted thioesterase General function prediction only 120404042 Common - short-chain dehydrogenase/reductase SDR Mvan_3063 227 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 120404029 Common - protein of unknown function DUF222 Mvan_3050 7 None None None 120406177 Common - hypothetical protein Mvan_5229 10 None None None 120401241 Common - NAD-dependent epimerase/dehydratase Mvan_0214 221 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 120401291 Common - acyl-CoA dehydrogenase domain protein Mvan_0265 146 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120403404 Common - nitrogen-fixing NifU domain protein Mvan_2413 19 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 120406229 Common - aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding Mvan_5281 122 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 120403159 Common coaD phosphopantetheine adenylyltransferase Mvan_2167 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 120406424 Common - ATPase associated with various cellular activities, AAA_5 Mvan_5478 92 COG0714 COG0714, MoxR-like ATPases General function prediction only 120401296 Common - condensation domain protein Mvan_0270 5 None None None 120406217 Common - 2-nitropropane dioxygenase, NPD Mvan_5269 133 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 120401143 Common - protein tyrosine/serine phosphatase Mvan_0115 51 COG2365 COG2365, Protein tyrosine/serine phosphatase Signal transduction mechanisms 120404160 Common - hypothetical protein Mvan_3181 3 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 120406711 Nonpathogen - hypothetical protein Mvan_5769 1 None None None 120401483 Common - transposase, IS4 family protein Mvan_0459 25 COG5421 COG5421, Transposase DNA replication, recombination, and repair 120401691 Common - hypothetical protein Mvan_0676 5 None None None 120401428 Common - acyl-CoA dehydrogenase domain protein Mvan_0403 140 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120405571 Common - Methyltransferase type 11 Mvan_4619 27 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 120405409 Common - hypothetical protein Mvan_4457 11 None None None 120403124 Common - 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase Mvan_2132 180 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 120405438 Common - hypothetical protein Mvan_4486 4 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 120402463 Common - hypothetical protein Mvan_1453 2 None None None 120401673 Common - narrowly conserved hypothetical protein Mvan_0658 37 COG2954 COG2954, Uncharacterized protein conserved in bacteria Function unknown 120401846 Common - two component transcriptional regulator, winged helix family Mvan_0831 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 120405884 Common - Carboxymuconolactone decarboxylase Mvan_4934 93 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 120405516 Common - SSS sodium solute transporter superfamily Mvan_4564 135 COG4147 DhlC, Predicted symporter General function prediction only 120406746 Common - cutinase Mvan_5804 3 None None None 120405029 Common - HAD-superfamily subfamily IB hydrolase, TIGR01490 Mvan_4075 167 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 120404163 Common - hypothetical protein Mvan_3184 2 None None None 120401758 Common - putative monovalent cation/H+ antiporter subunit C Mvan_0743 17 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 120406875 Common - phage integrase family protein Mvan_5935 30 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 120401332 Common - Integrase, catalytic region Mvan_0306 111 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 120401219 Common - integral membrane sensor signal transduction histidine kinase Mvan_0192 188 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 120403081 Common - enoyl-CoA hydratase Mvan_2089 100 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120404471 Common - UspA domain protein Mvan_3499 29 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 120401995 Common - hypothetical protein Mvan_0980 4 None None None 120404126 Common - amidohydrolase Mvan_3147 162 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 120401760 Common - TrkA-N domain protein Mvan_0745 103 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 120401037 Common - hypothetical protein Mvan_0009 14 COG1141 Fer, Ferredoxin Energy production and conversion 120402843 Common - amino acid permease-associated region Mvan_1845 159 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 120401541 Common - hypothetical protein Mvan_0520 3 None None None 120404421 Common - 20S proteasome, A and B subunits Mvan_3449 47 COG0638 PRE1, 20S proteasome, alpha and beta subunits Posttranslational modification, protein turnover, chaperones 120405358 Common - iron-containing alcohol dehydrogenase Mvan_4405 149 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 120402589 Common - isopentenyl-diphosphate delta-isomerase Mvan_1582 51 COG1443 Idi, Isopentenyldiphosphate isomerase Lipid metabolism 120404902 Common ndk nucleoside diphosphate kinase Mvan_3948 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 120405431 Common - short-chain dehydrogenase/reductase SDR Mvan_4479 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 120401839 Common - ErfK/YbiS/YcfS/YnhG family protein Mvan_0824 16 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 120403492 Common - hypothetical protein Mvan_2504 1 None None None 120405490 Common - Cl- channel, voltage-gated family protein Mvan_4538 28 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 120402268 Nonpathogen - hypothetical protein Mvan_1256 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 120406244 Common - xylulokinase Mvan_5296 164 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 120406431 Common - protein of unknown function DUF323 Mvan_5485 104 COG1262 COG1262, Uncharacterized conserved protein Function unknown 120403568 Common secD preprotein translocase subunit SecD Mvan_2583 200 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 120402681 Nonpathogen - hypothetical protein Mvan_1675 1 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 120406973 Nonpathogen - hypothetical protein Mvan_6043 6 COG5406 COG5406, Nucleosome binding factor SPN, SPT16 subunit Transcription / DNA replication, recombination, and repair / Chromatin structure and dynamics 120401770 Common - membrane-flanked domain Mvan_0755 15 COG3428 COG3428, Predicted membrane protein Function unknown 120405092 Common - protein of unknown function DUF35 Mvan_4138 31 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 120401082 Common - FAD dependent oxidoreductase Mvan_0054 80 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 120403379 Common - beta-lactamase domain protein Mvan_2388 162 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 120404901 Common - ribonuclease, Rne/Rng family Mvan_3947 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 120401280 Common - small secreted protein Mvan_0254 3 None None None 120402753 Common - integral membrane sensor signal transduction histidine kinase Mvan_1753 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 120401359 Common - protein of unknown function DUF1469 Mvan_0334 1 None None None 120404521 Common - AMP-dependent synthetase and ligase Mvan_3549 217 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 120405769 Common - diguanylate cyclase Mvan_4819 174 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 120406635 Common - sulphate transporter Mvan_5693 161 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 120402286 Common - putative conserved transmembrane protein Mvan_1275 1 None None None 120405914 Common - regulatory protein GntR, HTH Mvan_4965 119 COG2188 PhnF, Transcriptional regulators Transcription 120401373 Common - putative GAF sensor protein Mvan_0348 48 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 120406490 Common - nitroreductase Mvan_5547 66 COG0778 NfnB, Nitroreductase Energy production and conversion 120404058 Common - putative urease accessory protein Mvan_3079 6 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 120406882 Nonpathogen - hypothetical protein Mvan_5946 1 None None None 120405213 Common - luciferase family protein Mvan_4259 60 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120405330 Common - protein of unknown function DUF1460 Mvan_4377 21 None None None 120403641 Common - hypothetical protein Mvan_2657 5 None None None 120403361 Common - NHL repeat containing protein Mvan_2370 11 None None None 120405420 Common - FAD-binding 9, siderophore-interacting domain protein Mvan_4468 45 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 120401137 Common - Methyltransferase type 11 Mvan_0109 192 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 120406663 Common - hypothetical protein Mvan_5721 2 None None None 120406203 Common - protein of unknown function DUF35 Mvan_5255 30 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 120405446 Common - peptidase S1 and S6, chymotrypsin/Hap Mvan_4494 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 120405311 Nonpathogen - hypothetical protein Mvan_4357 1 None None None 120401988 Common - ThiJ/PfpI domain protein Mvan_0973 103 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 120401112 Common - hypothetical protein Mvan_0084 1 None None None 120405545 Common - short-chain dehydrogenase/reductase SDR Mvan_4593 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 120406045 Common - response regulator receiver protein Mvan_5097 195 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 120406853 Common - gluconate transporter Mvan_5912 76 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 120404793 Common - protein of unknown function DUF558 Mvan_3835 119 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 120401109 Common - protein of unknown function DUF571 Mvan_0081 2 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 120403468 Common - secretory lipase Mvan_2478 22 COG1031 COG1031, Uncharacterized Fe-S oxidoreductase Energy production and conversion 120404876 Common - degV family protein Mvan_3922 40 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 120406851 Common - GntR domain protein Mvan_5910 44 COG2186 FadR, Transcriptional regulators Transcription 120401329 Common - urea amidolyase related protein Mvan_0303 114 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 120404112 Common - protein of unknown function DUF151 Mvan_3133 75 COG1259 COG1259, Uncharacterized conserved protein Function unknown 120403800 Common trpC indole-3-glycerol-phosphate synthase Mvan_2816 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 120401601 Common - transposase, mutator type Mvan_0585 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 120402421 Common - branched-chain alpha-keto acid dehydrogenase subunit E2 Mvan_1410 194 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 120405410 Common - luciferase family protein Mvan_4458 113 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120401969 Common - hypothetical protein Mvan_0954 15 None None None 120406940 Nonpathogen - hypothetical protein Mvan_6008 1 None None None 120403671 Common fmt methionyl-tRNA formyltransferase Mvan_2687 214 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 120402230 Common - glycosyl transferase, group 1 Mvan_1218 146 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 120403322 Nonpathogen - hypothetical protein Mvan_2331 1 None None None 120404096 Common - hypothetical protein Mvan_3117 8 None None None 120404411 Common - hypothetical protein Mvan_3439 4 COG5028 COG5028, Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 Intracellular trafficking and secretion 120403517 Common - filamentation induced by cAMP protein Fic Mvan_2529 84 COG3177 COG3177, Uncharacterized conserved protein Function unknown 120406340 Common - hypothetical protein Mvan_5392 3 None None None 120402704 Common - protein tyrosine phosphatase Mvan_1702 26 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 120405729 Common - putative DNA-binding protein Mvan_4779 15 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 120404626 Nonpathogen - hypothetical protein Mvan_3662 1 None None None 120403842 Common - hypothetical protein Mvan_2859 1 None None None 120403807 Common - glutamate synthases, NADH/NADPH, small subunit Mvan_2823 188 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 120402646 Common - transcriptional regulator, TetR family Mvan_1640 71 COG1309 AcrR, Transcriptional regulator Transcription 120404554 Common - hypothetical protein Mvan_3583 19 None None None 120405538 Common - beta-Ig-H3/fasciclin Mvan_4586 50 COG2335 COG2335, Secreted and surface protein containing fasciclin-like repeats Cell envelope biogenesis, outer membrane 120403664 Common - glycosyl transferase, family 2 Mvan_2680 79 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 120404693 Common - ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member-like Mvan_3734 62 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 120405297 Common - hypothetical protein Mvan_4343 9 None None None 120406961 Common rplI 50S ribosomal protein L9 Mvan_6031 215 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 120403681 Common uvrC excinuclease ABC subunit C Mvan_2697 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 120406394 Common - phosphoesterase, PA-phosphatase related Mvan_5447 7 None None None 120406858 Common - short chain dehydrogenase Mvan_5918 234 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120405184 Common - Enoyl-CoA hydratase/isomerase Mvan_4230 124 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120406075 Common - hypothetical protein Mvan_5127 1 None None None 120402640 Common - hypothetical protein Mvan_1634 6 None None None 120404074 Common - protein of unknown function DUF21 Mvan_3095 212 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 120405239 Common - acyltransferase 3 Mvan_4285 49 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 120401074 Common - putative agmatinase Mvan_0046 155 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 120402982 Common - regulatory protein GntR, HTH Mvan_1986 112 COG2186 FadR, Transcriptional regulators Transcription 120403530 Common - binding-protein-dependent transport systems inner membrane component Mvan_2542 182 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 120404829 Common - regulatory protein, LuxR Mvan_3871 28 COG3899 COG3899, Predicted ATPase General function prediction only 120404921 Common - Phytanoyl-CoA dioxygenase Mvan_3967 16 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 120402442 Common infA translation initiation factor IF-1 Mvan_1431 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 120403168 Common - isopentenyl pyrophosphate isomerase Mvan_2176 80 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 120401057 Common - FHA domain containing protein Mvan_0029 37 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 120403758 Common - pseudouridine synthase, RluA family Mvan_2774 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 120406013 Common - beta-lactamase Mvan_5065 83 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 120405085 Common - twin-arginine translocation pathway signal Mvan_4131 5 None None None 120403856 Common - short-chain dehydrogenase/reductase SDR Mvan_2873 219 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 120405474 Common - acyl-CoA synthetase Mvan_4522 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120405533 Common - transposase IS116/IS110/IS902 family protein Mvan_4581 36 None None None 120405171 Common - acyl-CoA dehydrogenase domain protein Mvan_4217 140 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120403811 Common - ABC transporter-related protein Mvan_2827 42 COG4987 CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 120404743 Common - Rieske (2Fe-2S) domain protein Mvan_3784 62 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 120402992 Common - acyl-CoA dehydrogenase domain protein Mvan_1997 70 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120401124 Common - transcriptional regulator, DeoR family Mvan_0096 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 120402261 Common - glycoside hydrolase, family 38 Mvan_1249 47 COG0383 AMS1, Alpha-mannosidase Carbohydrate transport and metabolism 120403876 Common - ferredoxin Mvan_2893 143 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 120403901 Common - aminotransferase class-III Mvan_2918 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 120404883 Common - carbohydrate kinase, FGGY Mvan_3929 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 120402395 Common - hypothetical protein Mvan_1384 57 COG2187 COG2187, Uncharacterized protein conserved in bacteria Function unknown 120401537 Common - virulence factor Mce family protein Mvan_0516 19 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120404222 Common - hypothetical protein Mvan_3245 28 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 120402244 Common - hypothetical protein Mvan_1232 22 COG2030 MaoC, Acyl dehydratase Lipid metabolism 120401201 Common - dihydroxy-acid dehydratase Mvan_0173 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 120403653 Common - bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase Mvan_2669 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 120402482 Common - hypothetical protein Mvan_1473 1 None None None 120401475 Common - transcriptional regulator, XRE family Mvan_0450 122 COG1396 HipB, Predicted transcriptional regulators Transcription 120403891 Nonpathogen - hypothetical protein Mvan_2908 3 COG3476 COG3476, Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) Signal transduction mechanisms 120403751 Common - hypothetical protein Mvan_2767 1 None None None 120405106 Common - protein of unknown function DUF140 Mvan_4152 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 120405706 Nonpathogen - hypothetical protein Mvan_4756 1 None None None 120405240 Common - non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family Mvan_4286 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 120405744 Nonpathogen - hypothetical protein Mvan_4794 1 None None None 120405162 Common - L-carnitine dehydratase/bile acid-inducible protein F Mvan_4208 113 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 120406689 Nonpathogen - hypothetical protein Mvan_5747 1 None None None 120402017 Nonpathogen - Sterol-binding domain protein Mvan_1002 6 COG3154 COG3154, Putative lipid carrier protein Lipid metabolism 120403136 Common - protein of unknown function DUF222 Mvan_2144 5 None None None 120403493 Nonpathogen - hypothetical protein Mvan_2505 2 None None None 120406903 Common - transposase IS3/IS911 family protein Mvan_5969 4 None None None 120404150 Common - sterol desaturase-related protein Mvan_3171 69 COG3000 ERG3, Sterol desaturase Lipid metabolism 120406921 Common - hypothetical protein Mvan_5988 3 None None None 120401050 Common - para-aminobenzoate synthase component II Mvan_0022 235 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 120402099 Nonpathogen - hypothetical protein Mvan_1085 1 None None None 120403831 Common - hypothetical protein Mvan_2847 1 None None None 120403344 Common - hypothetical protein Mvan_2353 11 None None None 120404962 Common - AMP-dependent synthetase and ligase Mvan_4008 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120403046 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mvan_2052 49 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 120404928 Common - cytochrome P450 Mvan_3974 86 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120404820 Common - hypothetical protein Mvan_3862 1 None None None 120406365 Common - phage integrase family protein Mvan_5418 80 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 120403507 Nonpathogen - hypothetical protein Mvan_2519 1 COG1403 McrA, Restriction endonuclease Defense mechanisms 120405693 Common - amidohydrolase Mvan_4743 170 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 120404969 Common - UbiC transcription regulator-associated domain protein Mvan_4015 128 COG2188 PhnF, Transcriptional regulators Transcription 120401102 Common - cell divisionFtsK/SpoIIIE Mvan_0074 194 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 120403272 Common - short chain dehydrogenase Mvan_2281 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120404943 Common - short-chain dehydrogenase/reductase SDR Mvan_3989 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120404960 Common - acyl-CoA dehydrogenase domain protein Mvan_4006 154 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120401612 Common - acetaldehyde dehydrogenase Mvan_0596 37 COG4569 MhpF, Acetaldehyde dehydrogenase (acetylating) Secondary metabolites biosynthesis, transport, and catabolism 120406706 Nonpathogen - hypothetical protein Mvan_5764 3 None None None 120403983 Common - dihydrodipicolinate reductase Mvan_3001 23 COG3804 COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase Function unknown 120404818 Common - protein of unknown function DUF21 Mvan_3860 218 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 120406080 Common - putative FAD-binding dehydrogenase Mvan_5132 27 COG3573 COG3573, Predicted oxidoreductase General function prediction only 120405230 Common - transcriptional regulator, AraC family Mvan_4276 66 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 120406659 Common - Methyltransferase type 11 Mvan_5717 189 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 120405755 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mvan_4805 116 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 120405110 Common - aldehyde dehydrogenase Mvan_4156 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 120401307 Common - acyl-CoA dehydrogenase domain protein Mvan_0281 95 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120405363 Common - MaoC domain protein dehydratase Mvan_4410 61 COG2030 MaoC, Acyl dehydratase Lipid metabolism 120403282 Common - cobalamin (vitamin B12) biosynthesis CbiM protein Mvan_2291 80 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 120402104 Common - transposase IS3/IS911 family protein Mvan_1090 56 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 120405724 Common - protein of unknown function DUF451 Mvan_4774 29 COG2822 COG2822, Predicted periplasmic lipoprotein involved in iron transport Inorganic ion transport and metabolism 120402528 Common - FAD dependent oxidoreductase Mvan_1519 91 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 120403747 Common - methylmalonyl-CoA mutase Mvan_2763 111 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 120402049 Common - CsbD-like protein Mvan_1034 2 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 120404663 Common - acyltransferase 3 Mvan_3701 71 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 120405261 Common - hypothetical protein Mvan_4307 14 None None None 120406350 Nonpathogen - hypothetical protein Mvan_5402 1 None None None 120405758 Common - Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase Mvan_4808 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 120406066 Common - hypothetical protein Mvan_5118 16 COG4425 COG4425, Predicted membrane protein Function unknown 120402435 Common - sodium/hydrogen exchanger Mvan_1424 142 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 120403088 Common - glycosyl transferase, group 1 Mvan_2096 221 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 120402802 Common - hypothetical protein Mvan_1803 23 COG4270 COG4270, Predicted membrane protein Function unknown 120404265 Common - hemolysin A Mvan_3290 132 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 120406739 Common - hypothetical protein Mvan_5797 10 None None None 120406565 Nonpathogen - aminoglycoside phosphotransferase Mvan_5623 3 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 120405386 Common - extracellular solute-binding protein, family 5 Mvan_4433 140 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 120405686 Common - hypothetical protein Mvan_4735 1 None None None 120402912 Common - protein of unknown function DUF214 Mvan_1915 74 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 120404848 Nonpathogen - hypothetical protein Mvan_3892 1 None None None 120403894 Common - ribonuclease T2 Mvan_2911 40 COG3719 Rna, Ribonuclease I Translation, ribosomal structure and biogenesis 120402098 Common - alpha/beta hydrolase fold Mvan_1084 95 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120404763 Common - cobalt transport protein Mvan_3805 9 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 120402497 Common - ribosomal-protein-alanine acetyltransferase Mvan_1488 174 COG0456 RimI, Acetyltransferases General function prediction only 120404237 Common - Resolvase, N-terminal domain Mvan_3261 95 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 120404958 Common - luciferase family protein Mvan_4004 102 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120401220 Common - putative conserved transmembrane protein Mvan_0193 10 None None None 120404493 Common - Polypeptide-transport-associated domain protein, FtsQ-type Mvan_3521 19 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 120404634 Common - heavy metal translocating P-type ATPase Mvan_3670 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 120402125 Common - Integrase, catalytic region Mvan_1111 124 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 120404299 Common - tRNA/rRNA methyltransferase (SpoU) Mvan_3325 214 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 120402287 Common - hypothetical protein Mvan_1276 3 None None None 120402424 Common - GAF sensor signal transduction histidine kinase Mvan_1413 49 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 120403908 Common - YaeQ family protein Mvan_2925 52 COG4681 COG4681, Uncharacterized protein conserved in bacteria Function unknown 120403006 Common - Rieske (2Fe-2S) domain protein Mvan_2012 70 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 120405584 Common - hypothetical protein Mvan_4632 4 None None None 120406897 Nonpathogen - hypothetical protein Mvan_5962 1 None None None 120402413 Common - UspA domain protein Mvan_1402 16 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 120402919 Common - Cupin 2, conserved barrel domain protein Mvan_1922 16 COG2140 COG2140, Thermophilic glucose-6-phosphate isomerase and related metalloenzymes Carbohydrate transport and metabolism / General function prediction only 120405300 Common - homoserine kinase Mvan_4346 67 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 120406220 Common ectC L-ectoine synthase Mvan_5272 35 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 120404424 Common - hypothetical protein Mvan_3452 3 None None None 120403626 Common - Holliday junction resolvase YqgF Mvan_2641 154 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 120406076 Common - phosphoribosylformylglycinamidine synthase subunit I Mvan_5128 229 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 120402449 Common truA tRNA pseudouridine synthase A Mvan_1438 234 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 120406161 Common - hypothetical protein Mvan_5213 94 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 120403033 Common - NADPH-dependent FMN reductase Mvan_2039 96 COG0431 COG0431, Predicted flavoprotein General function prediction only 120403055 Nonpathogen - hypothetical protein Mvan_2061 1 None None None 120401864 Nonpathogen - hypothetical protein Mvan_0849 1 None None None 120402932 Common - TRAP transporter solute receptor, TAXI family Mvan_1935 93 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 120403479 Common - hypothetical protein Mvan_2490 71 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 120401741 Common - major facilitator superfamily MFS_1 Mvan_0726 181 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120402134 Nonpathogen - hypothetical protein Mvan_1121 1 None None None 120401571 Common - transposase, mutator type Mvan_0550 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 120404918 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit beta Mvan_3964 115 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 120406403 Common - protein of unknown function DUF58 Mvan_5456 36 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 120403290 Common - hypothetical protein Mvan_2299 15 COG2267 PldB, Lysophospholipase Lipid metabolism 120402867 Common - aminoglycoside phosphotransferase Mvan_1869 56 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 120402295 Common - major facilitator superfamily MFS_1 Mvan_1284 203 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120406846 Common - thioredoxin Mvan_5905 231 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 120401092 Common - hypothetical protein Mvan_0064 11 None None None 120401527 Common - heavy metal translocating P-type ATPase Mvan_0505 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 120405985 Common - tRNA/rRNA methyltransferase (SpoU) Mvan_5036 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 120404701 Common - transposase IS3/IS911 family protein Mvan_3742 36 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 120402853 Common - L-carnitine dehydratase/bile acid-inducible protein F Mvan_1855 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 120403179 Common - ribosomal protein S16 Mvan_2187 212 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 120404328 Common - DGPFAETKE family protein Mvan_3354 22 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 120401921 Common - acyl-CoA dehydrogenase domain protein Mvan_0906 161 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120406304 Common - hypothetical protein Mvan_5356 13 None None None 120401611 Common - 4-oxalocrotonate decarboxylase Mvan_0595 64 COG3971 COG3971, 2-keto-4-pentenoate hydratase Secondary metabolites biosynthesis, transport, and catabolism 120401516 Nonpathogen - Sterol-binding domain protein Mvan_0494 4 COG3255 COG3255, Putative sterol carrier protein Lipid metabolism 120405120 Common - Rieske (2Fe-2S) domain protein Mvan_4166 40 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 120404676 Common - copper resistance protein CopC Mvan_3714 52 COG2372 CopC, Uncharacterized protein, homolog of Cu resistance protein CopC General function prediction only 120401254 Common - protein of unknown function UPF0089 Mvan_0228 28 None None None 120405645 Common - protein kinase Mvan_4693 153 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 120405449 Common - O-methyltransferase, family 3 Mvan_4497 99 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 120403965 Common - ferric uptake regulator, Fur family Mvan_2983 127 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 120401194 Common - hypothetical protein Mvan_0166 11 None None None 120405138 Common - Rieske (2Fe-2S) domain protein Mvan_4184 78 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 120402653 Common - histidine kinase Mvan_1647 114 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 120403286 Common - integral membrane sensor signal transduction histidine kinase Mvan_2295 217 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 120401565 Common - 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase Mvan_0544 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120406283 Common - hypothetical protein Mvan_5335 5 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 120405926 Common - hypothetical protein Mvan_4977 1 None None None 120402720 Common - 40-residue YVTN family beta-propeller repeat protein Mvan_1720 135 COG3391 COG3391, Uncharacterized conserved protein Function unknown 120404104 Common - beta-ketoacyl synthase Mvan_3125 210 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 120405656 Common - ABC transporter-related protein Mvan_4704 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 120402942 Common - acyl-CoA synthetase Mvan_1945 193 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120403584 Common - Radical SAM domain protein Mvan_2599 104 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 120405606 Common - Integrase, catalytic region Mvan_4654 63 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 120403838 Common - virulence factor Mce family protein Mvan_2854 33 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120406574 Common - cell wall arabinan synthesis protein Mvan_5632 5 None None None 120401251 Common - Alpha/beta hydrolase fold-3 domain protein Mvan_0225 122 COG0657 Aes, Esterase/lipase Lipid metabolism 120402275 Nonpathogen - Collagen triple helix repeat Mvan_1264 1 None None None 120403481 Common - GCN5-related N-acetyltransferase Mvan_2492 35 COG0456 RimI, Acetyltransferases General function prediction only 120402729 Common - Nucleotidyl transferase Mvan_1729 235 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 120404193 Common - hypothetical protein Mvan_3215 5 None None None 120401683 Common - hypothetical protein Mvan_0668 155 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 120402372 Common - acyl-CoA dehydrogenase domain protein Mvan_1361 165 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120403925 Common - regulatory protein GntR, HTH Mvan_2942 128 COG2186 FadR, Transcriptional regulators Transcription 120405877 Common - RNA polymerase sigma factor SigK Mvan_4927 101 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 120402052 Common - putative anti-sigma regulatory factor, serine/threonine protein kinase Mvan_1037 5 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 120406148 Common - virulence factor Mce family protein Mvan_5200 29 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120401653 Common - putative transcriptional regulator, MerR family Mvan_0637 36 COG0789 SoxR, Predicted transcriptional regulators Transcription 120401404 Common - cobalbumin biosynthesis enzyme Mvan_0379 82 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 120406949 Nonpathogen - hypothetical protein Mvan_6017 1 None None None 120402114 Common - ADP-ribosylation/Crystallin J1 Mvan_1100 13 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 120402885 Common - hypothetical protein Mvan_1887 3 None None None 120401750 Common - superoxide dismutase, copper/zinc binding Mvan_0735 77 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 120406508 Common - aldehyde dehydrogenase Mvan_5566 64 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 120401905 Common - hypothetical protein Mvan_0890 1 None None None 120402868 Common - transcriptional regulator, TetR family Mvan_1870 43 COG1309 AcrR, Transcriptional regulator Transcription 120402655 Common - UspA domain protein Mvan_1649 59 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 120403477 Common - putative conserved integral membrane protein Mvan_2488 4 None None None 120403614 Common - protein of unknown function DUF404 Mvan_2629 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 120404272 Common - ABC drug efflux pump, inner membrane subunit, DrrB family Mvan_3297 93 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 120404982 Common - Rhodanese domain protein Mvan_4028 77 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 120405293 Common prfA peptide chain release factor 1 Mvan_4339 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 120402687 Common - lipopolysaccharide biosynthesis Mvan_1681 199 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 120402032 Common - Glucarate dehydratase Mvan_1017 64 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 120406807 Common - protein of unknown function DUF222 Mvan_5865 7 None None None 120405080 Common - putative transcriptional regulator, MerR family Mvan_4126 10 COG0789 SoxR, Predicted transcriptional regulators Transcription 120405481 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Mvan_4529 144 COG1146 COG1146, Ferredoxin Energy production and conversion 120406582 Common - beta-ketoacyl synthase Mvan_5640 210 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 120406501 Common - ErfK/YbiS/YcfS/YnhG family protein Mvan_5559 16 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 120405551 Common - virulence factor Mce family protein Mvan_4599 24 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120404589 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Mvan_3621 141 COG0546 Gph, Predicted phosphatases General function prediction only 120401325 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Mvan_0299 125 COG1146 COG1146, Ferredoxin Energy production and conversion 120402698 Nonpathogen - hypothetical protein Mvan_1693 1 None None None 120403528 Common - hypothetical protein Mvan_2540 14 None None None 120404995 Common tig trigger factor Mvan_4041 215 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 120405618 Common - hypothetical protein Mvan_4666 1 None None None 120405127 Common - 6-phosphogluconate dehydrogenase, NAD-binding Mvan_4173 162 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 120402354 Common - signal peptide peptidase SppA, 67K type Mvan_1343 182 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 120402329 Common - hypothetical protein Mvan_1318 1 None None None 120404636 Common - multicopper oxidase, type 2 Mvan_3672 123 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 120405611 Common - hypothetical protein Mvan_4659 1 None None None 120404651 Common - NLP/P60 protein Mvan_3688 106 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 120402327 Common - hypothetical protein Mvan_1316 6 None None None 120402914 Common - protein of unknown function DUF6, transmembrane Mvan_1917 6 COG2510 COG2510, Predicted membrane protein Function unknown 120405348 Common - virulence factor Mce family protein Mvan_4395 6 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120404577 Common - hypothetical protein Mvan_3608 3 None None None 120403014 Common - putative oxidoreductase Mvan_2020 41 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120403699 Common - hypothetical protein Mvan_2715 2 None None None 120404240 Common - transposase Mvan_3264 76 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 120402695 Common - hypothetical protein Mvan_1690 1 None None None 120403924 Nonpathogen - hypothetical protein Mvan_2941 1 None None None 120406357 Common - protein of unknown function DUF302 Mvan_5410 41 COG3439 COG3439, Uncharacterized conserved protein Function unknown 120406110 Common - hypothetical protein Mvan_5162 14 COG1141 Fer, Ferredoxin Energy production and conversion 120403501 Common - hypothetical protein Mvan_2513 7 COG3598 RepA, RecA-family ATPase DNA replication, recombination, and repair 120403713 Common - ABC drug efflux pump, inner membrane subunit, DrrB family Mvan_2729 13 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 120403888 Common - phosphonate ABC transporter, ATPase subunit Mvan_2905 249 COG3638 COG3638, ABC-type phosphate/phosphonate transport system, ATPase component Inorganic ion transport and metabolism 120404021 Common - drug resistance transporter, EmrB/QacA subfamily Mvan_3042 206 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120406795 Common - heavy metal translocating P-type ATPase Mvan_5853 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 120404340 Common - lipid-transfer protein Mvan_3366 90 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120402393 Common - UspA domain protein Mvan_1382 11 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 120402044 Common - Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein Mvan_1029 109 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 120405044 Common - Carbamoyl-phosphate synthase L chain, ATP-binding Mvan_4090 236 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 120406457 Common - transcriptional regulator, XRE family Mvan_5514 60 COG1396 HipB, Predicted transcriptional regulators Transcription 120405546 Common - transcriptional regulator, TetR family Mvan_4594 17 COG1309 AcrR, Transcriptional regulator Transcription 120404480 Common - short-chain dehydrogenase/reductase SDR Mvan_3508 236 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 120404485 Common - phosphoribosyltransferase Mvan_3513 69 COG1926 COG1926, Predicted phosphoribosyltransferases General function prediction only 120404209 Common - protein of unknown function DUF222 Mvan_3231 7 None None None 120405997 Common - thiamineS protein Mvan_5048 12 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 120403244 Common - protein of unknown function UPF0089 Mvan_2253 28 None None None 120404545 Common gcvT glycine cleavage system aminomethyltransferase T Mvan_3574 179 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 120404875 Common - transposase IS116/IS110/IS902 family protein Mvan_3921 30 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 120404775 Common - hypothetical protein Mvan_3817 9 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 120405357 Common - intradiol ring-cleavage dioxygenase Mvan_4404 47 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 120405130 Common - hypothetical protein Mvan_4176 9 COG1141 Fer, Ferredoxin Energy production and conversion 120404970 Common - PfkB domain protein Mvan_4016 160 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 120403495 Common - hypothetical protein Mvan_2507 31 None None None 120406389 Common - glycosyl transferase, family 51 Mvan_5442 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 120405063 Common - pyruvate flavodoxin/ferredoxin oxidoreductase domain protein Mvan_4109 129 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 120406911 Nonpathogen - hypothetical protein Mvan_5978 1 None None None 120402054 Common - hypothetical protein Mvan_1039 3 None None None 120401060 Nonpathogen - transcriptional regulator, Fis family Mvan_0032 1 COG1480 COG1480, Predicted membrane-associated HD superfamily hydrolase General function prediction only 120405716 Common - hypothetical protein Mvan_4766 8 None None None 120406898 Nonpathogen - hypothetical protein Mvan_5963 1 None None None 120406276 Common - regulatory protein, ArsR Mvan_5328 30 COG0640 ArsR, Predicted transcriptional regulators Transcription 120401798 Common - protein of unknown function DUF417 Mvan_0783 27 COG3059 COG3059, Predicted membrane protein Function unknown 120401845 Common - histidine kinase Mvan_0830 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 120406245 Common - hypothetical protein Mvan_5297 5 None None None 120405774 Common - hypothetical protein Mvan_4824 3 COG3428 COG3428, Predicted membrane protein Function unknown 120402899 Common - putative esterase Mvan_1902 13 COG0627 COG0627, Predicted esterase General function prediction only 120401128 Common - membrane protein-like protein Mvan_0100 36 COG1289 COG1289, Predicted membrane protein Function unknown 120403226 Common - putative ferredoxin Mvan_2235 14 COG1141 Fer, Ferredoxin Energy production and conversion 120406331 Common - beta-lactamase Mvan_5383 67 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 120401738 Common - hypothetical protein Mvan_0723 35 COG3571 COG3571, Predicted hydrolase of the alpha/beta-hydrolase fold General function prediction only 120405135 Common - Carboxymuconolactone decarboxylase Mvan_4181 28 COG2128 COG2128, Uncharacterized conserved protein Function unknown 120406311 Common - aspartate alpha-decarboxylase Mvan_5363 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 120404756 Common - hypothetical protein Mvan_3798 4 None None None 120404380 Common tynA tyramine oxidase Mvan_3407 22 COG3733 TynA, Cu2+-containing amine oxidase Secondary metabolites biosynthesis, transport, and catabolism 120402024 Common - putative outer membrane adhesin like proteiin Mvan_1009 41 None None None 120406352 Common - hypothetical protein Mvan_5404 3 None None None 120402109 Common - transposase IS3/IS911 family protein Mvan_1095 4 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 120405848 Common - 5-oxoprolinase (ATP-hydrolyzing) Mvan_4898 116 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120403418 Common - ABC transporter-related protein Mvan_2428 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 120401841 Common - ROK family protein Mvan_0826 47 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 120405068 Common - Hydrogen dehydrogenase Mvan_4114 49 COG1941 FrhG, Coenzyme F420-reducing hydrogenase, gamma subunit Energy production and conversion 120403082 Common - Methyltransferase type 11 Mvan_2090 82 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 120405361 Common - AMP-dependent synthetase and ligase Mvan_4408 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120403604 Common - photosystem I assembly BtpA Mvan_2619 42 COG0434 SgcQ, Predicted TIM-barrel enzyme General function prediction only 120406542 Common - ABC transporter-related protein Mvan_5600 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 120403238 Common - luciferase family protein Mvan_2247 61 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120405465 Common - hypothetical protein Mvan_4513 1 None None None 120401509 Common - aromatic-ring-hydroxylating dioxygenase, beta subunit Mvan_0487 29 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 120403989 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mvan_3007 29 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 120404844 Common - putative monooxygenase Mvan_3887 72 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120405562 Common - hypothetical protein Mvan_4610 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 120404976 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mvan_4022 107 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 120405197 Common - 3-ketosteroid-delta-1-dehydrogenase Mvan_4243 59 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 120402152 Common - zinc finger, SWIM domain protein Mvan_1139 12 COG4715 COG4715, Uncharacterized conserved protein Function unknown 120406201 Common - lipid-transfer protein Mvan_5253 90 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120406636 Common - hypothetical protein Mvan_5694 7 None None None 120403212 Common frr ribosome recycling factor Mvan_2221 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 120405489 Common - 2-nitropropane dioxygenase, NPD Mvan_4537 58 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 120406932 Common - Radical SAM domain protein Mvan_6000 7 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 120403407 Common - hydrogenase accessory protein HypB Mvan_2417 128 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 120403778 Common - hypothetical protein Mvan_2794 6 None None None 120406747 Common - putative GAF sensor protein Mvan_5805 98 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 120406151 Common - protein of unknown function DUF140 Mvan_5203 133 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 120401494 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mvan_0470 27 None None None 120402304 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Mvan_1293 30 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 120402815 Common - FAD linked oxidase domain protein Mvan_1816 49 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 120401134 Common - short-chain dehydrogenase/reductase SDR Mvan_0106 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120404113 Common - putative transcriptional regulator, MerR family Mvan_3134 20 COG0789 SoxR, Predicted transcriptional regulators Transcription 120404368 Common - short chain dehydrogenase Mvan_3394 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120406172 Common - major facilitator superfamily MFS_1 Mvan_5224 26 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120405525 Common - MMPL domain protein Mvan_4573 38 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 120405957 Common - Ion transport 2 domain protein Mvan_5008 95 COG1226 Kch, Kef-type K+ transport systems, predicted NAD-binding component Inorganic ion transport and metabolism 120402568 Common - putative ribonuclease Mvan_1561 34 COG1295 Rbn, Predicted membrane protein Function unknown 120401645 Common - luciferase family protein Mvan_0629 77 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120404224 Nonpathogen - hypothetical protein Mvan_3247 1 None None None 120403936 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mvan_2953 157 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 120401886 Common - hypothetical protein Mvan_0871 1 None None None 120406239 Common - inner-membrane translocator Mvan_5291 107 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 120401493 Common - dihydrodipicolinate synthetase Mvan_0469 208 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 120404361 Common - spermidine/putrescine ABC transporter ATPase subunit Mvan_3387 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 120406838 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mvan_5896 5 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 120405921 Common - hypothetical protein Mvan_4972 1 None None None 120405305 Nonpathogen - hypothetical protein Mvan_4351 1 None None None 120405312 Nonpathogen - hypothetical protein Mvan_4358 2 None None None 120403982 Common - short-chain dehydrogenase/reductase SDR Mvan_3000 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120401934 Common - hypothetical protein Mvan_0919 6 None None None 120403523 Common - PE-PPE, C-terminal domain protein Mvan_2535 2 None None None 120406230 Common - acetyl-CoA acetyltransferase Mvan_5282 187 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120404414 Common - twin-arginine translocation protein, TatA/E family subunit Mvan_3442 57 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 120403639 Common - HpcH/HpaI aldolase Mvan_2654 103 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 120403373 Common - hypothetical protein Mvan_2382 6 None None None 120401557 Common - 6-phosphogluconate dehydrogenase, NAD-binding Mvan_0536 14 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 120401584 Common - 3-oxoacid CoA-transferase, B subunit Mvan_0565 91 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 120404857 Common - Tn554-related, transposase C Mvan_3902 8 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 120406874 Common - phage integrase family protein Mvan_5934 5 None None None 120403651 Common gmk guanylate kinase Mvan_2667 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 120403440 Common - iron dependent repressor Mvan_2450 84 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 120404835 Common - glycoside hydrolase 15-related Mvan_3877 69 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 120401466 Common - short-chain dehydrogenase/reductase SDR Mvan_0441 234 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120402080 Common - protein of unknown function UPF0089 Mvan_1065 28 COG4908 COG4908, Uncharacterized protein containing a NRPS condensation (elongation) domain General function prediction only 120403037 Nonpathogen - hypothetical protein Mvan_2043 1 None None None 120404202 Common - regulatory protein, ArsR Mvan_3224 144 COG0640 ArsR, Predicted transcriptional regulators Transcription 120406395 Common - luciferase family protein Mvan_5448 59 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120402833 Common - two component transcriptional regulator, winged helix family Mvan_1834 216 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 120402438 Common - two component transcriptional regulator, LuxR family Mvan_1427 207 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 120402195 Common - AAA ATPase Mvan_1183 31 COG0433 COG0433, Predicted ATPase General function prediction only 120401955 Common - hypothetical protein Mvan_0940 1 None None None 120403581 Common - Extracellular ligand-binding receptor Mvan_2596 145 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 120405681 Common - hypothetical protein Mvan_4730 1 None None None 120401155 Common - protein of unknown function DUF72 Mvan_0127 110 COG1801 COG1801, Uncharacterized conserved protein Function unknown 120404142 Common - ABC transporter domain protein Mvan_3163 248 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 120403521 Nonpathogen - hypothetical protein Mvan_2533 1 None None None 120401701 Common - hypothetical protein Mvan_0686 1 None None None 120406646 Common - O-methyltransferase domain protein Mvan_5704 34 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 120401595 Common - transposase IS3/IS911 family protein Mvan_0578 59 None None None 120401609 Common - monooxygenase, FAD-binding Mvan_0593 99 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 120401504 Common - Integrase, catalytic region Mvan_0482 57 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 120403455 Common - hypothetical protein Mvan_2465 19 None None None 120402767 Common - fatty acid desaturase Mvan_1768 31 COG3239 DesA, Fatty acid desaturase Lipid metabolism 120405001 Common - phospholipid/glycerol acyltransferase Mvan_4047 27 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 120406000 Common - molybdenum cofactor synthesis domain Mvan_5051 186 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 120401757 Common - putative monovalent cation/H+ antiporter subunit D Mvan_0742 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 120401638 Common - hypothetical protein Mvan_0622 1 None None None 120405329 Common - Lytic transglycosylase, catalytic Mvan_4376 14 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 120406106 Common - transcriptional regulator, TetR family Mvan_5158 3 COG1309 AcrR, Transcriptional regulator Transcription 120402130 Common - hypothetical protein Mvan_1117 1 None None None 120405411 Common - Uracil-DNA glycosylase superfamily Mvan_4459 63 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 120402011 Common - protein of unknown function DUF1023 Mvan_0996 1 None None None 120405709 Common - potassium-transporting ATPase subunit A Mvan_4759 96 COG2060 KdpA, K+-transporting ATPase, A chain Inorganic ion transport and metabolism 120406487 Nonpathogen - hypothetical protein Mvan_5544 4 None None None 120403094 Common - Cupin 2, conserved barrel domain protein Mvan_2102 2 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 120403231 Common - Alcohol dehydrogenase, zinc-binding domain protein Mvan_2240 37 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 120403957 Common - protein of unknown function DUF1688 Mvan_2975 10 None None None 120403676 Common - protein of unknown function DUF1396 Mvan_2692 5 None None None 120404688 Common - regulatory protein, ArsR Mvan_3728 165 COG0640 ArsR, Predicted transcriptional regulators Transcription 120402470 Nonpathogen - hypothetical protein Mvan_1460 1 None None None 120405350 Common - virulence factor Mce family protein Mvan_4397 22 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120401443 Common - hypothetical protein Mvan_0418 1 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 120403071 Common - hypothetical protein Mvan_2079 3 None None None 120406969 Common - transcriptional regulator, PadR-like family Mvan_6039 42 COG1695 COG1695, Predicted transcriptional regulators Transcription 120405815 Common - hypothetical protein Mvan_4865 1 None None None 120404646 Common - regulatory protein, ArsR Mvan_3682 98 COG0640 ArsR, Predicted transcriptional regulators Transcription 120406215 Common - coenzyme A transferase Mvan_5267 51 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 120402365 Common - 3-Oxoacyl-(acyl-carrier-protein (ACP)) synthase III C terminal domain protein Mvan_1354 160 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 120402087 Common - beta-lactamase Mvan_1072 115 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 120406292 Common - hypothetical protein Mvan_5344 10 None None None 120406464 Common - CobB/CobQ domain protein glutamine amidotransferase Mvan_5521 96 COG3442 COG3442, Predicted glutamine amidotransferase General function prediction only 120402572 Common - response regulator receiver protein Mvan_1565 44 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 120406888 Nonpathogen - hypothetical protein Mvan_5952 1 None None None 120403300 Common - conserved hypothetical alanine rich protein Mvan_2309 7 None None None 120403354 Common - helix-turn-helix- domain containing protein, AraC type Mvan_2363 41 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 120401405 Common - hypothetical protein Mvan_0380 14 None None None 120407005 Common - protein of unknown function DUF37 Mvan_6076 184 COG0759 COG0759, Uncharacterized conserved protein Function unknown 120404329 Common - putative RNA polymerase, sigma-24 subunit, ECF subfamily Mvan_3355 41 COG4941 COG4941, Predicted RNA polymerase sigma factor containing a TPR repeat domain Transcription 120403303 Common nusA transcription elongation factor NusA Mvan_2312 228 COG0195 NusA, Transcription elongation factor Transcription 120401286 Common - acetyl-CoA acetyltransferase Mvan_0260 171 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120406956 Common - UvrD/REP helicase Mvan_6025 62 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 120405990 Common - putative conserved exported protein Mvan_5041 4 None None None 120403191 Common - AMP-dependent synthetase and ligase Mvan_2199 206 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120404797 Common - two component transcriptional regulator, winged helix family Mvan_3839 216 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 120405036 Common - Methyltransferase type 12 Mvan_4082 39 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 120406321 Common - alpha/beta hydrolase fold Mvan_5373 150 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120405372 Common - transcriptional regulator, BadM/Rrf2 family Mvan_4419 174 COG1959 COG1959, Predicted transcriptional regulator Transcription 120406268 Common - periplasmic solute binding protein Mvan_5320 48 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 120402061 Nonpathogen - hypothetical protein Mvan_1046 1 None None None 120402137 Common - VanW family protein Mvan_1124 38 COG2720 COG2720, Uncharacterized vancomycin resistance protein Defense mechanisms 120405635 Common - Rhodanese domain protein Mvan_4683 26 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 120406447 Common - aspartate kinase Mvan_5504 233 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 120406262 Common - Methyltransferase type 11 Mvan_5314 57 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 120404009 Common - cytochrome P450 Mvan_3029 69 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120406812 Common - phosphonate metabolism PhnJ Mvan_5870 45 COG3627 PhnJ, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 120406475 Common - Cyclopropane-fatty-acyl-phospholipid synthase Mvan_5532 135 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 120405692 Common - transposase, mutator type Mvan_4741 82 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 120401900 Common - two component transcriptional regulator, winged helix family Mvan_0885 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 120404865 Common - protein of unknown function DUF404 Mvan_3911 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 120402797 Common - hypothetical protein Mvan_1798 5 None None None 120405919 Common - dihydrodipicolinate reductase Mvan_4970 19 COG3804 COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase Function unknown 120403974 Common - hypothetical protein Mvan_2992 42 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 120404305 Common - putative esterase Mvan_3331 25 COG0627 COG0627, Predicted esterase General function prediction only 120405882 Common - cytochrome c oxidase, subunit III Mvan_4932 56 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 120404175 Common - ethanolamine transproter Mvan_3196 145 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 120403648 Common carB carbamoyl phosphate synthase large subunit Mvan_2664 234 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 120403030 Common - putative GAF sensor protein Mvan_2036 31 COG2203 FhlA, FOG: GAF domain Signal transduction mechanisms 120401087 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Mvan_0059 14 COG3871 COG3871, Uncharacterized stress protein (general stress protein 26) General function prediction only 120404562 Common - DoxX family protein Mvan_3593 60 COG2259 COG2259, Predicted membrane protein Function unknown 120406726 Common - MscS Mechanosensitive ion channel Mvan_5784 43 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 120406716 Common - HNH endonuclease Mvan_5774 5 None None None 120403390 Common - putative conserved membrane alanine rich protein Mvan_2399 4 None None None 120402503 Common groES co-chaperonin GroES Mvan_1494 215 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 120406979 Common - transcriptional regulator, MarR family Mvan_6049 13 COG1846 MarR, Transcriptional regulators Transcription 120401694 Common - diguanylate cyclase Mvan_0679 107 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 120403595 Common - Enoyl-CoA hydratase/isomerase Mvan_2610 180 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120406149 Common - virulence factor Mce family protein Mvan_5201 30 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120406430 Common - hypothetical protein Mvan_5484 42 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 120401413 Common - Xylose isomerase domain protein TIM barrel Mvan_0388 22 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 120406299 Common - alpha/beta hydrolase fold Mvan_5351 75 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120402414 Common - hypothetical protein Mvan_1403 17 COG5502 COG5502, Uncharacterized conserved protein Function unknown 120403427 Common - DEAD/DEAH box helicase domain protein Mvan_2437 233 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 120405282 Common - F0F1 ATP synthase subunit beta Mvan_4328 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 120403026 Common - transcriptional regulator, TetR family Mvan_2032 22 COG1309 AcrR, Transcriptional regulator Transcription 120401313 Common - putative succinate dehydrogenase (membrane anchor subunit) (succinic dehydrogenase) Mvan_0287 10 None None None 120403700 Common - 6-phosphogluconolactonase Mvan_2716 91 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 120404732 Common - extracellular solute-binding protein, family 5 Mvan_3773 211 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 120404811 Nonpathogen - hypothetical protein Mvan_3853 1 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 120402780 Common - signal transduction histidine kinase Mvan_1781 116 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 120405986 Common - hypothetical protein Mvan_5037 4 None None None 120401212 Common - hypothetical protein Mvan_0185 1 None None None 120401626 Common - hypothetical protein Mvan_0610 2 None None None 120403569 Common secF preprotein translocase subunit SecF Mvan_2584 203 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 120404334 Common - transcriptional regulator, TetR family Mvan_3360 4 COG1309 AcrR, Transcriptional regulator Transcription 120403560 Common ruvA Holliday junction DNA helicase motor protein Mvan_2574 210 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 120404352 Common - hypothetical protein Mvan_3378 22 None None None 120406382 Common - putative transcriptional regulator, Crp/Fnr family Mvan_5435 166 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 120402545 Common - Roadblock/LC7 family protein Mvan_1537 10 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 120406226 Common - monooxygenase, FAD-binding Mvan_5278 79 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 120402928 Common - multi-sensor signal transduction histidine kinase Mvan_1931 226 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 120405087 Common - acyl-CoA synthetase Mvan_4133 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120406861 Common - transcriptional regulator, TetR family Mvan_5921 4 COG1309 AcrR, Transcriptional regulator Transcription 120406196 Common - glycosyl transferase, group 1 Mvan_5248 164 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 120402758 Common - transposase, IS4 family protein Mvan_1758 25 COG5421 COG5421, Transposase DNA replication, recombination, and repair 120402439 Common - band 7 protein Mvan_1428 61 COG2268 COG2268, Uncharacterized protein conserved in bacteria Function unknown 120404504 Common - hypothetical protein Mvan_3532 128 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 120402223 Common - metal dependent phosphohydrolase Mvan_1211 169 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 120404649 Common - hypothetical protein Mvan_3685 20 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 120402606 Common upp uracil phosphoribosyltransferase Mvan_1600 164 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 120403313 Common - peptidase S15 Mvan_2322 62 COG2936 COG2936, Predicted acyl esterases General function prediction only 120403999 Common - ErfK/YbiS/YcfS/YnhG family protein Mvan_3019 27 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 120403900 Common - amidohydrolase 2 Mvan_2917 7 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 120405931 Nonpathogen - hypothetical protein Mvan_4982 1 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 120402772 Common - methyltransferase small Mvan_1773 38 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 120401121 Common - Phosphotransferase system, phosphocarrier protein HPr Mvan_0093 15 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 120406306 Common - ATPase AAA-2 domain protein Mvan_5358 222 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 120404537 Common - Adenosine kinase Mvan_3566 99 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 120403911 Common - Integrase, catalytic region Mvan_2928 49 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 120406538 Common - prephenate dehydrogenase Mvan_5596 141 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 120405061 Common - HAD-superfamily hydrolase, subfamily IIB Mvan_4107 115 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 120402842 Common - aldehyde dehydrogenase Mvan_1844 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 120402228 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mvan_1216 158 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 120405450 Common - transcriptional regulator, TetR family Mvan_4498 8 COG1309 AcrR, Transcriptional regulator Transcription 120401267 Common - Methyltransferase type 11 Mvan_0241 43 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 120401301 Common - transcriptional regulator, TetR family Mvan_0275 62 COG1309 AcrR, Transcriptional regulator Transcription 120406609 Common - glycerophosphoryl diester phosphodiesterase Mvan_5667 104 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 120405895 Common - protein of unknown function DUF985 Mvan_4946 55 COG3542 COG3542, Uncharacterized conserved protein Function unknown 120406025 Common - transcriptional regulator, TetR family Mvan_5077 26 COG1309 AcrR, Transcriptional regulator Transcription 120401067 Nonpathogen - hypothetical protein Mvan_0039 1 None None None 120406600 Common - hypothetical protein Mvan_5658 2 None None None 120406920 Common - von Willebrand factor, type A Mvan_5987 17 COG4245 TerY, Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain General function prediction only 120401709 Nonpathogen - Activator of Hsp90 ATPase 1 family protein Mvan_0694 3 COG3832 COG3832, Uncharacterized conserved protein Function unknown 120406667 Common - hypothetical protein Mvan_5725 5 None None None 120405072 Common - hypothetical protein Mvan_4118 1 None None None 120404450 Common - cysteinyl-tRNA synthetase Mvan_3478 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 120405796 Common - protein of unknown function DUF1446 Mvan_4846 35 None None None 120405925 Common - hypothetical protein Mvan_4976 1 None None None 120404189 Nonpathogen - hypothetical protein Mvan_3211 1 COG4982 COG4982, 3-oxoacyl- acyl-carrier protein 120405647 Common - hypothetical protein Mvan_4695 1 None None None 120405908 Common - L-carnitine dehydratase/bile acid-inducible protein F Mvan_4959 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 120405788 Common mscL large-conductance mechanosensitive channel Mvan_4838 130 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 120405805 Common - hypothetical protein Mvan_4855 1 None None None 120401533 Common - protein of unknown function DUF955 Mvan_0511 20 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 120401274 Common - hypothetical protein Mvan_0248 1 None None None 120406524 Common - hypothetical protein Mvan_5582 3 None None None 120403187 Common - hypothetical protein Mvan_2195 17 None None None 120403792 Common - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase Mvan_2808 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 120403946 Common - hypothetical protein Mvan_2963 2 None None None 120405328 Nonpathogen - hypothetical protein Mvan_4375 1 None None None 120404575 Nonpathogen - hypothetical protein Mvan_3606 1 None None None 120402143 Common - Patatin Mvan_1130 17 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 120402516 Common - hypothetical protein Mvan_1507 4 None None None 120401049 Common - PE-PPE, C-terminal domain protein Mvan_0021 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 120403818 Common - ABC transporter-related protein Mvan_2834 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 120402789 Common - hypothetical protein Mvan_1790 5 None None None 120402066 Common - acyl-CoA synthetase Mvan_1051 217 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120403209 Common tynA tyramine oxidase Mvan_2218 22 COG3733 TynA, Cu2+-containing amine oxidase Secondary metabolites biosynthesis, transport, and catabolism 120401950 Common - allantoicase Mvan_0935 15 COG4266 Alc, Allantoicase Nucleotide transport and metabolism 120402496 Common - peptidase M22, glycoprotease Mvan_1487 184 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 120404320 Common - small multidrug resistance protein Mvan_3346 115 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 120401262 Common - helix-turn-helix- domain containing protein, AraC type Mvan_0236 49 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 120403698 Common - protein of unknown function DUF222 Mvan_2714 5 None None None 120402117 Common - metallophosphoesterase Mvan_1103 62 None None None 120401321 Common - hypothetical protein Mvan_0295 5 None None None 120404317 Nonpathogen - FHA domain containing protein Mvan_3343 1 COG3456 COG3456, Uncharacterized conserved protein, contains FHA domain Signal transduction mechanisms 120401579 Common - protocatechuate 3,4-dioxygenase, beta subunit Mvan_0560 49 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 120401545 Common - transcriptional regulator, MarR family Mvan_0524 2 COG1846 MarR, Transcriptional regulators Transcription 120404519 Common - cyclase/dehydrase Mvan_3547 8 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 120402217 Common - hypothetical protein Mvan_1205 1 None None None 120403100 Common - Methionine synthase, vitamin-B12 independent Mvan_2108 23 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 120405961 Common - hypothetical protein Mvan_5012 10 None None None 120404569 Common - TAP domain protein Mvan_3600 38 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120405004 Common - sodium/hydrogen exchanger Mvan_4050 52 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 120402630 Common - short-chain dehydrogenase/reductase SDR Mvan_1624 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120404466 Common - nitrite reductase (NAD(P)H), large subunit Mvan_3494 202 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 120406221 Common - diaminobutyrate--2-oxoglutarate aminotransferase Mvan_5273 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 120406549 Common - Cupin 2, conserved barrel domain protein Mvan_5607 15 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 120405901 Common - amidohydrolase 2 Mvan_4952 52 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 120406081 Common - hypothetical protein Mvan_5133 6 COG3233 COG3233, Predicted deacetylase General function prediction only 120402770 Common - 3-phosphoshikimate 1-carboxyvinyltransferase Mvan_1771 228 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 120405927 Common - hypothetical protein Mvan_4978 1 None None None 120406708 Common - ATP-dependent helicase HrpA Mvan_5766 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 120403688 Common pgk phosphoglycerate kinase Mvan_2704 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 120405119 Common - amidohydrolase 2 Mvan_4165 17 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 120406303 Common - hypothetical protein Mvan_5355 11 COG5446 COG5446, Predicted integral membrane protein Function unknown 120406819 Common - phosphonate ABC transporter, periplasmic phosphonate-binding protein Mvan_5877 77 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 120401716 Common - acetate kinase Mvan_0701 162 COG0282 ackA, Acetate kinase Energy production and conversion 120403836 Common - virulence factor Mce family protein Mvan_2852 18 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120403870 Common - NADH:flavin oxidoreductase/NADH oxidase Mvan_2887 179 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 120404366 Common - protein of unknown function DUF6, transmembrane Mvan_3392 57 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 120403829 Common - ABC transporter-related protein Mvan_2845 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 120401881 Common - Redoxin domain protein Mvan_0866 121 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 120403382 Common - 3-ketoacyl-(acyl-carrier-protein) reductase Mvan_2391 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120401198 Common - transcriptional regulator, TetR family Mvan_0170 113 COG1309 AcrR, Transcriptional regulator Transcription 161899025 Common - 3-ketosteroid-delta-1-dehydrogenase Mvan_5237 62 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 120401631 Common - Cyclohexanone monooxygenase Mvan_0615 54 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 120401230 Common - Carotenoid oxygenase Mvan_0203 36 COG3670 COG3670, Lignostilbene-alpha,beta-dioxygenase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 120405224 Common - acyl-CoA dehydrogenase domain protein Mvan_4270 135 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120401593 Common - Integrase, catalytic region Mvan_0575 146 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 120406669 Common - putative PAS/PAC sensor protein Mvan_5727 8 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 120403443 Common - hypothetical protein Mvan_2453 17 None None None 120403996 Common - transcriptional regulator, XRE family Mvan_3014 31 COG1396 HipB, Predicted transcriptional regulators Transcription 120405950 Common - NmrA family protein Mvan_5001 25 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 120406051 Nonpathogen - protein of unknown function DUF732 Mvan_5103 2 None None None 120401773 Common - hypothetical protein Mvan_0758 6 None None None 120404372 Common - transcriptional regulator, TetR family Mvan_3399 3 COG1309 AcrR, Transcriptional regulator Transcription 120401239 Common - C-methyltransferase Mvan_0212 34 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 120404426 Common - hypothetical protein Mvan_3454 3 None None None 120405685 Common - transcriptional regulator, LysR family Mvan_4734 170 COG0583 LysR, Transcriptional regulator Transcription 120406844 Common - hypothetical protein Mvan_5903 1 None None None 120401174 Common - SMP-30/gluconolaconase/LRE-like region Mvan_0146 67 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 120404637 Nonpathogen - hypothetical protein Mvan_3673 1 None None None 120405720 Common - Septum formation initiator Mvan_4770 17 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 120405380 Common - glycosyl transferase, family 39 Mvan_4427 17 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 120406187 Nonpathogen - putative alanine and proline rich membrane protein Mvan_5239 1 None None None 120401365 Common - Enoyl-CoA hydratase/isomerase Mvan_0340 162 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120401659 Common - hypothetical protein Mvan_0643 19 COG3224 COG3224, Uncharacterized protein conserved in bacteria Function unknown 120403040 Common - hypothetical protein Mvan_2046 2 None None None 120405509 Common - hypothetical protein Mvan_4557 1 None None None 120402526 Common - transcriptional activator, TenA family Mvan_1517 8 COG0819 TenA, Putative transcription activator Transcription 120402947 Common - phosphoglucomutase Mvan_1950 153 COG0033 Pgm, Phosphoglucomutase Carbohydrate transport and metabolism 120405266 Common - acyl-CoA dehydrogenase domain protein Mvan_4312 132 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120404097 Common - O-methyltransferase domain protein Mvan_3118 37 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 120401279 Common - putative conserved transmembrane protein Mvan_0253 9 None None None 120403368 Common - hypothetical protein Mvan_2377 1 None None None 120404761 Common - hypothetical protein Mvan_3803 39 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 120401888 Nonpathogen - protein of unknown function DUF1486 Mvan_0873 2 None None None 120405722 Common - putative conserved lipoprotein LpqU Mvan_4772 21 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 120404177 Common - ethanolamine ammonia-lyase small subunit Mvan_3198 52 COG4302 EutC, Ethanolamine ammonia-lyase, small subunit Amino acid transport and metabolism 120404263 Common - DNA repair protein RecN Mvan_3288 198 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 120403730 Common - hypothetical protein Mvan_2746 3 None None None 120403247 Common - short-chain dehydrogenase/reductase SDR Mvan_2256 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120405139 Common - short-chain dehydrogenase/reductase SDR Mvan_4185 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120405912 Common - short-chain dehydrogenase/reductase SDR Mvan_4963 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120401242 Common - glucose-1-phosphate cytidylyltransferase Mvan_0216 171 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 120402639 Common - regulatory protein, LuxR Mvan_1633 51 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 120401193 Nonpathogen - hypothetical protein Mvan_0165 1 None None None 120401256 Common - putative transcriptional regulator, TetR family Mvan_0230 2 None None None 120402018 Common - beta-ketoacyl synthase Mvan_1003 224 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 120404090 Nonpathogen - hypothetical protein Mvan_3111 1 None None None 120406349 Common - protein kinase Mvan_5401 150 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 120401986 Common - O-succinylbenzoate synthase Mvan_0971 14 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 120406554 Nonpathogen - hypothetical protein Mvan_5612 1 None None None 120402432 Common - ATP-binding region, ATPase domain protein domain protein Mvan_1421 119 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 120405377 Common - carbonic anhydrase Mvan_4424 46 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 120401618 Common - hypothetical protein Mvan_0602 2 None None None 120401834 Common - cytochrome c oxidase, subunit III Mvan_0819 101 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 120404115 Common - glycine cleavage system protein H Mvan_3136 185 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 120402426 Common - UspA domain protein Mvan_1415 41 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 120403221 Common - hypothetical protein Mvan_2230 21 None None None 120401878 Common - amidohydrolase Mvan_0863 176 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 120403112 Common - DoxX family protein Mvan_2120 20 COG2259 COG2259, Predicted membrane protein Function unknown 120403534 Common - alpha amylase, catalytic region Mvan_2546 159 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 120402489 Common - D-fructose-6-phosphate amidotransferase Mvan_1480 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 120401939 Common - virulence factor Mce family protein Mvan_0924 9 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120401056 Common - FHA domain containing protein Mvan_0028 43 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 120402446 Common rpsD 30S ribosomal protein S4 Mvan_1435 247 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 120403737 Common - enoyl-(acyl carrier protein) reductase Mvan_2753 174 COG0623 FabI, Enoyl- acyl-carrier-protein 120405597 Common - protein of unknown function UPF0118 Mvan_4645 151 COG0628 PerM, Predicted permease General function prediction only 120403170 Common - ammonium transporter Mvan_2178 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 120405879 Common - uncharacterized enzyme Mvan_4929 60 COG2170 COG2170, Uncharacterized conserved protein Function unknown 120401510 Common - ring hydroxylating dioxygenase, alpha subunit Mvan_0488 84 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 120404249 Common engA GTP-binding protein EngA Mvan_3274 219 COG1160 COG1160, Predicted GTPases General function prediction only 120403532 Common - extracellular solute-binding protein, family 1 Mvan_2544 60 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 120405776 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mvan_4826 26 None None None 120404691 Common - hypothetical protein Mvan_3732 5 None None None 120404248 Common - hypothetical protein Mvan_3273 2 COG3874 COG3874, Uncharacterized conserved protein Function unknown 120406010 Common - luciferase family protein Mvan_5062 54 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120403898 Nonpathogen - hypothetical protein Mvan_2915 1 None None None 120404377 Common - hypothetical protein Mvan_3404 2 None None None 120404703 Nonpathogen - hypothetical protein Mvan_3744 1 None None None 120405444 Common - protein of unknown function DUF59 Mvan_4492 232 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 120406910 Nonpathogen - hypothetical protein Mvan_5977 1 None None None 120403437 Common - hypothetical protein Mvan_2447 5 COG3591 COG3591, V8-like Glu-specific endopeptidase Amino acid transport and metabolism 120402030 Common - hypothetical protein Mvan_1015 1 COG5373 COG5373, Predicted membrane protein Function unknown 120406943 Common - hypothetical protein Mvan_6011 3 None None None 120403844 Common - hypothetical protein Mvan_2861 2 None None None 120404091 Common - alpha/beta hydrolase fold Mvan_3112 61 COG2267 PldB, Lysophospholipase Lipid metabolism 120404686 Common - cation diffusion facilitator family transporter Mvan_3726 184 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 120403655 Common - Cyclohexanone monooxygenase Mvan_2671 66 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 120402883 Common - NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Mvan_1885 163 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 120401997 Common - short chain dehydrogenase Mvan_0982 235 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 120406788 Common - protein of unknown function DUF202 Mvan_5846 19 COG2149 COG2149, Predicted membrane protein Function unknown 120403189 Common - L-carnitine dehydratase/bile acid-inducible protein F Mvan_2197 110 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 120405590 Common - putative nonspecific acid phosphatase precursor Mvan_4638 25 None None None 120402135 Common - hypothetical protein Mvan_1122 5 None None None 120406798 Common - Pyridoxal-5'-phosphate-dependent enzyme, beta subunit Mvan_5856 217 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 120406634 Common - regulatory protein, ArsR Mvan_5692 63 COG0640 ArsR, Predicted transcriptional regulators Transcription 120404739 Common - transcriptional regulator, TetR family Mvan_3780 3 None None None 120405313 Nonpathogen - hypothetical protein Mvan_4359 1 None None None 120401917 Common - protein of unknown function DUF35 Mvan_0902 8 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 120405487 Common - LmbE family protein Mvan_4535 29 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 120403161 Common - hypothetical protein Mvan_2169 17 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 120404624 Common - Integrase, catalytic region Mvan_3659 145 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 120401357 Nonpathogen - hypothetical protein Mvan_0332 1 None None None 120402849 Common - extracellular solute-binding protein, family 3 Mvan_1851 116 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 120404355 Common - hypothetical protein Mvan_3381 13 None None None 120401440 Common - PPE protein Mvan_0415 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 120405178 Common - protein of unknown function UPF0089 Mvan_4224 25 None None None 120403667 Common - YhhN family protein Mvan_2683 11 COG3714 COG3714, Predicted membrane protein Function unknown 120402375 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Mvan_1364 157 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 120403826 Common - inner-membrane translocator Mvan_2842 143 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 120403962 Common - glutamine amidotransferase Mvan_2980 83 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 120404512 Common - phospho-2-dehydro-3-deoxyheptonate aldolase Mvan_3540 73 COG3200 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 120402096 Nonpathogen - hypothetical protein Mvan_1082 1 COG2213 MtlA, Phosphotransferase system, mannitol-specific IIBC component Carbohydrate transport and metabolism 120402701 Nonpathogen - hypothetical protein Mvan_1698 2 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 120405749 Common - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase Mvan_4799 183 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 120401394 Common - transcriptional regulator, TetR family Mvan_0369 11 COG1309 AcrR, Transcriptional regulator Transcription 120405237 Common - lipoprotein, putative Mvan_4283 6 COG4578 GutM, Glucitol operon activator Transcription 120406963 Common - single-strand DNA-binding protein Mvan_6033 155 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 120405024 Common - putative ABC transporter ATP-binding protein Mvan_4070 246 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 120403628 Common aroE shikimate 5-dehydrogenase Mvan_2643 216 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 120404552 Common lipB lipoyltransferase Mvan_3581 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 120405738 Common - peptidyl-tRNA hydrolase Mvan_4788 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 120401572 Common - hypothetical protein Mvan_0551 2 None None None 120403814 Common - cytochrome bd ubiquinol oxidase, subunit I Mvan_2830 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 120405108 Common - protein of unknown function DUF35 Mvan_4154 3 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 120406136 Common - protein of unknown function DUF222 Mvan_5188 5 None None None 120401856 Common - phospholipid/glycerol acyltransferase Mvan_0841 53 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 120404415 Common - transcriptional regulator-like protein Mvan_3443 35 COG2378 COG2378, Predicted transcriptional regulator Transcription 120404813 Common - coproporphyrinogen III oxidase Mvan_3855 205 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 120404917 Common - molybdopterin-guanine dinucleotide biosynthesis protein A Mvan_3963 5 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 120402267 Nonpathogen - hypothetical protein Mvan_1255 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 120402987 Common - short-chain dehydrogenase/reductase SDR Mvan_1991 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120402469 Nonpathogen - hypothetical protein Mvan_1459 1 None None None 120402294 Common - cutinase Mvan_1283 4 None None None 120401660 Common - Acetamidase/Formamidase Mvan_0644 62 COG2421 COG2421, Predicted acetamidase/formamidase Energy production and conversion 120406995 Common - hypothetical protein Mvan_6066 2 None None None 120405422 Common - DEAD/DEAH box helicase domain protein Mvan_4470 234 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 120403519 Common - RNA polymerase, sigma 28 subunit, FliA/WhiG family Mvan_2531 210 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 120406742 Common - major facilitator superfamily MFS_1 Mvan_5800 72 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120404769 Nonpathogen - hypothetical protein Mvan_3811 1 None None None 120403250 Common - beta-Ig-H3/fasciclin Mvan_2259 62 COG2335 COG2335, Secreted and surface protein containing fasciclin-like repeats Cell envelope biogenesis, outer membrane 120406360 Common - hypothetical protein Mvan_5413 3 COG3462 COG3462, Predicted membrane protein Function unknown 120405243 Common - glutamate racemase Mvan_4289 189 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 120404149 Common - FAD dependent oxidoreductase Mvan_3170 90 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 120404926 Nonpathogen - hypothetical protein Mvan_3972 1 None None None 120404400 Nonpathogen - hypothetical protein Mvan_3428 1 None None None 120406885 Nonpathogen - hypothetical protein Mvan_5949 1 None None None 120406097 Common - putative esterase Mvan_5149 4 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 120402440 Common - hypothetical protein Mvan_1429 1 None None None 120404327 Common coaE dephospho-CoA kinase/unknown domain fusion protein Mvan_3353 207 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 120402462 Nonpathogen - hypothetical protein Mvan_1452 1 None None None 120402480 Nonpathogen - hypothetical protein Mvan_1471 1 None None None 120402505 Common - hypothetical protein Mvan_1496 6 None None None 120401966 Common - major facilitator superfamily MFS_1 Mvan_0951 81 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 120403138 Common - phage integrase family protein Mvan_2146 79 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 120405387 Common - alpha/beta hydrolase fold Mvan_4434 8 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120405757 Common - para-aminobenzoate synthase component I Mvan_4807 221 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 120402878 Common - NADH-quinone oxidoreductase, F subunit Mvan_1880 167 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 120406529 Common - hypothetical protein Mvan_5587 2 None None None 120401111 Nonpathogen - hypothetical protein Mvan_0083 1 None None None 120402723 Nonpathogen - hypothetical protein Mvan_1723 1 None None None 120405872 Common - dihydrodipicolinate reductase Mvan_4922 22 COG3804 COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase Function unknown 120403805 Common - hypothetical protein Mvan_2821 10 None None None 120402186 Common - hypothetical protein Mvan_1174 2 None None None 120405768 Common - cyclic nucleotide-binding protein Mvan_4818 76 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 120404103 Common - beta-ketoacyl synthase Mvan_3124 209 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 120405255 Common - alpha amylase, catalytic region Mvan_4301 92 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 120406034 Common - putative TIM-barrel protein, nifR3 family Mvan_5086 206 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 120401535 Common - phage integrase family protein Mvan_0513 9 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 120401623 Common - short-chain dehydrogenase/reductase SDR Mvan_0607 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120404252 Common - putative transcriptional regulator Mvan_3277 142 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 120406405 Common - hypothetical protein Mvan_5458 38 COG1300 SpoIIM, Uncharacterized membrane protein Function unknown 120402179 Common - protein of unknown function DUF894, DitE Mvan_1167 89 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120401210 Nonpathogen - hypothetical protein Mvan_0182 1 None None None 120403346 Common - alanine dehydrogenase Mvan_2355 166 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 120404218 Common - cadmium resistance transporter Mvan_3241 17 COG4300 CadD, Predicted permease, cadmium resistance protein Inorganic ion transport and metabolism 120402706 Common - Di-trans-poly-cis-decaprenylcistransferase Mvan_1705 190 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 120406848 Common - integral membrane sensor signal transduction histidine kinase Mvan_5907 134 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 120404620 Common - transcriptional repressor, CopY family Mvan_3655 22 COG3682 COG3682, Predicted transcriptional regulator Transcription 120403487 Common - hypothetical protein Mvan_2498 6 None None None 120406164 Common - enoyl-CoA hydratase Mvan_5216 180 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120406658 Common - hypothetical protein Mvan_5716 12 None None None 120401139 Nonpathogen - hypothetical protein Mvan_0111 1 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 120406497 Common - peptidase M56, BlaR1 Mvan_5555 13 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 120402962 Common - hypothetical protein Mvan_1966 1 None None None 120401072 Common - short-chain dehydrogenase/reductase SDR Mvan_0044 234 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120403557 Nonpathogen - hypothetical protein Mvan_2571 1 None None None 120402730 Common - hypothetical protein Mvan_1730 8 None None None 120402242 Common - hypothetical protein Mvan_1230 17 COG2030 MaoC, Acyl dehydratase Lipid metabolism 120404023 Common - FadD16 Mvan_3044 1 None None None 120401680 Common - transcriptional regulator, TetR family Mvan_0665 17 COG1309 AcrR, Transcriptional regulator Transcription 120403752 Common - hypothetical protein Mvan_2768 1 None None None 120404283 Common - argininosuccinate synthase Mvan_3308 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 120405959 Common - integral membrane sensor signal transduction histidine kinase Mvan_5010 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 120406859 Common - kumamolisin Mvan_5919 27 COG4934 COG4934, Predicted protease Posttranslational modification, protein turnover, chaperones 120406591 Common - glycosyltransferases-like protein Mvan_5649 21 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 120405742 Common - transcriptional regulator, TetR family Mvan_4792 70 COG1309 AcrR, Transcriptional regulator Transcription 120406901 Nonpathogen - hypothetical protein Mvan_5966 1 None None None 120404197 Common - major facilitator superfamily MFS_1 Mvan_3219 51 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120406409 Common - transcriptional regulator, PadR-like family Mvan_5462 73 COG1695 COG1695, Predicted transcriptional regulators Transcription 120401381 Common - Acyl-CoA dehydrogenase, type 2, C-terminal domain Mvan_0356 136 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120406015 Common - acetyl-CoA acetyltransferase Mvan_5067 169 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120405984 Common - hypothetical protein Mvan_5035 1 None None None 120401454 Common - phosphoesterase, PA-phosphatase related Mvan_0429 1 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 120406985 Nonpathogen - hypothetical protein Mvan_6056 1 None None None 120403615 Common - transglutaminase, N-terminal domain protein Mvan_2630 81 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 120402755 Common - Rieske (2Fe-2S) domain protein Mvan_1755 62 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 120404171 Common - hypothetical protein Mvan_3192 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 120405015 Common - hypothetical protein Mvan_4061 8 None None None 120401223 Common - conserved large membrane protein Mvan_0196 38 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 120403490 Common - Integrase, catalytic region Mvan_2501 49 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 120404862 Common - ribonuclease Z Mvan_3908 112 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 120405432 Common - Substrate-binding region of ABC-type glycine betaine transport system Mvan_4480 15 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 120403421 Common - protein of unknown function DUF349 Mvan_2431 29 COG4717 COG4717, Uncharacterized conserved protein Function unknown 120406568 Common - GtrA family protein Mvan_5626 6 COG2246 COG2246, Predicted membrane protein Function unknown 120401098 Common - hypothetical protein Mvan_0070 3 None None None 120401416 Common - methionine aminopeptidase, type I Mvan_0391 236 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 120404407 Common - short-chain dehydrogenase/reductase SDR Mvan_3435 200 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 120402022 Common - hypothetical protein Mvan_1007 11 None None None 120406452 Common - Glutamate--ammonia ligase Mvan_5509 223 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 120401696 Common - putative ferredoxin Mvan_0681 18 COG1141 Fer, Ferredoxin Energy production and conversion 120406078 Common - hypothetical protein Mvan_5130 1 None None None 120402447 Common - DNA-directed RNA polymerase subunit alpha Mvan_1436 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 120406871 Common - Transposase and inactivated derivatives-like Mvan_5931 47 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 120401079 Common - magnesium transporter Mvan_0051 171 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 120404035 Common - integral membrane protein Mvan_3056 2 COG1511 COG1511, Predicted membrane protein Function unknown 120406425 Common - iron-containing alcohol dehydrogenase Mvan_5479 168 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 120405945 Common - hypothetical protein Mvan_4996 32 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 120401604 Common - Cupin 2, conserved barrel domain protein Mvan_0588 4 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 120403572 Common - (p)ppGpp synthetase I, SpoT/RelA Mvan_2587 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 120405492 Common - GTP-binding protein TypA Mvan_4540 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 120405663 Nonpathogen - hypothetical protein Mvan_4711 1 None None None 120405825 Common - acyltransferase 3 Mvan_4875 77 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 120406970 Common - Myo-inositol-1-phosphate synthase Mvan_6040 56 COG1260 INO1, Myo-inositol-1-phosphate synthase Lipid metabolism 120403543 Common - thioesterase superfamily protein Mvan_2556 8 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 120404891 Common - regulatory protein, ArsR Mvan_3937 52 COG0640 ArsR, Predicted transcriptional regulators Transcription 120402280 Common - acyl-CoA dehydrogenase domain protein Mvan_1269 144 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120406597 Common - phospholipid/glycerol acyltransferase Mvan_5655 111 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 120403405 Common - Integrase, catalytic region Mvan_2415 15 None None None 120401647 Common - putative lipoprotein LpqJ Mvan_0631 1 None None None 120404034 Common - transcriptional regulator, TetR family Mvan_3055 5 COG1309 AcrR, Transcriptional regulator Transcription 120402535 Common - Inosine/uridine-preferring nucleoside hydrolase Mvan_1526 82 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 120406598 Common - phospholipid/glycerol acyltransferase Mvan_5656 142 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 120404904 Common - FolC bifunctional protein Mvan_3950 214 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 120405335 Common - protein of unknown function DUF899, thioredoxin family protein Mvan_4382 29 COG4312 COG4312, Uncharacterized protein conserved in bacteria Function unknown 120401531 Nonpathogen - hypothetical protein Mvan_0509 1 None None None 120404935 Common - virulence factor Mce family protein Mvan_3981 8 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120402289 Common - transcriptional regulator, TetR family Mvan_1278 29 COG1309 AcrR, Transcriptional regulator Transcription 120401670 Nonpathogen - hypothetical protein Mvan_0655 1 None None None 120402166 Nonpathogen - hypothetical protein Mvan_1154 1 None None None 120404060 Common - urease accessory protein UreF Mvan_3081 6 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 120404945 Common - putative GAF sensor protein Mvan_3991 137 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 120405117 Common - acyl-CoA dehydrogenase domain protein Mvan_4163 104 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120404491 Common - protein of unknown function DUF152 Mvan_3519 163 COG1496 COG1496, Uncharacterized conserved protein Function unknown 120404535 Common - cytochrome c oxidase, subunit II Mvan_3564 129 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 120401542 Common - Epoxide hydrolase domain protein Mvan_0521 36 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120402969 Common - short-chain dehydrogenase/reductase SDR Mvan_1973 234 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120404259 Common - hypothetical protein Mvan_3284 10 None None None 120404594 Common - multicopper oxidase, type 3 Mvan_3626 101 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 120401039 Common - integral membrane sensor signal transduction histidine kinase Mvan_0011 214 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 120402551 Common - hypothetical protein Mvan_1544 1 None None None 120405608 Common glyA serine hydroxymethyltransferase Mvan_4656 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 120402889 Common - aminoglycoside phosphotransferase Mvan_1891 53 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 120405215 Common - methylmalonyl-CoA mutase, large subunit Mvan_4261 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 120404587 Common - protein of unknown function DUF164 Mvan_3619 19 COG1579 COG1579, Zn-ribbon protein, possibly nucleic acid-binding General function prediction only 120404155 Common - protein of unknown function DUF222 Mvan_3176 5 COG5373 COG5373, Predicted membrane protein Function unknown 120406134 Common - (2Fe-2S)-binding domain protein Mvan_5186 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 120404085 Common - PE-PPE, C-terminal domain protein Mvan_3106 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 120405677 Common - PE-PPE, C-terminal domain protein Mvan_4726 1 None None None 120405544 Common - DoxX family protein Mvan_4592 47 COG2259 COG2259, Predicted membrane protein Function unknown 120402896 Common - hypothetical protein Mvan_1899 3 None None None 120404933 Common - virulence factor Mce family protein Mvan_3979 10 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120401488 Common - 3-phenylpropionate dioxygenase subunit beta Mvan_0464 20 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 120406052 Nonpathogen - hypothetical protein Mvan_5104 1 None None None 120403053 Common - putative monooxygenase Mvan_2059 73 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 120401297 Common - Transport protein Mvan_0271 72 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 120404528 Common - cytochrome c oxidase, subunit III Mvan_3557 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 120405731 Common - GreA/GreB family elongation factor Mvan_4781 22 COG0782 GreA, Transcription elongation factor Transcription 120405835 Common - luciferase family protein Mvan_4885 34 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120405206 Common - short-chain dehydrogenase/reductase SDR Mvan_4252 230 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 120406006 Common - hypothetical protein Mvan_5058 16 None None None 120401721 Common - NUDIX hydrolase Mvan_0706 10 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 120405573 Common - protein of unknown function DUF222 Mvan_4621 6 COG3000 ERG3, Sterol desaturase Lipid metabolism 120405338 Common - integral membrane sensor signal transduction histidine kinase Mvan_4385 136 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 120401145 Common - FAD dependent oxidoreductase Mvan_0117 70 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 120406712 Common - hypothetical protein Mvan_5770 2 None None None 120402383 Common - UspA domain protein Mvan_1372 2 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 120404526 Common - hypothetical protein Mvan_3554 5 None None None 120402574 Common - Chloride peroxidase Mvan_1567 141 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120403963 Common - globin Mvan_2981 31 COG2346 COG2346, Truncated hemoglobins General function prediction only 120404478 Common - hypothetical protein Mvan_3506 1 None None None 120402712 Nonpathogen - integral membrane protein possibly involved in chromosome condensation Mvan_1711 1 None None None 120402882 Common - NADH dehydrogenase subunit B Mvan_1884 191 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 120401768 Common - short chain dehydrogenase Mvan_0753 151 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120402452 Common - Cutinase Mvan_1441 3 None None None 120404059 Common - urease accessory protein UreG Mvan_3080 135 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 120404152 Common - Acyl-CoA dehydrogenase, type 2, C-terminal domain Mvan_3173 85 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120401334 Common - periplasmic binding protein Mvan_0308 41 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 120406787 Nonpathogen - protein of unknown function DUF202 Mvan_5845 1 None None None 120406671 Common - glycogen debranching enzyme GlgX Mvan_5729 160 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 120401094 Common - Propionyl-CoA carboxylase Mvan_0066 164 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 120406820 Common - metallophosphoesterase Mvan_5878 6 None None None 120401912 Common - regulatory proteins, IclR Mvan_0897 86 COG1414 IclR, Transcriptional regulator Transcription 120401376 Common - hypothetical protein Mvan_0351 3 None None None 120404745 Nonpathogen - branched-chain amino acid transport Mvan_3786 2 COG1687 AzlD, Predicted branched-chain amino acid permeases (azaleucine resistance) Amino acid transport and metabolism 120404602 Common - regulatory protein, ArsR Mvan_3634 21 COG0640 ArsR, Predicted transcriptional regulators Transcription 120406603 Common - Phosphoglycerate mutase Mvan_5661 54 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 120403768 Common - malto-oligosyltrehalose trehalohydrolase Mvan_2784 158 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 120403922 Nonpathogen - prevent-host-death family protein Mvan_2939 4 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 120402331 Common - protein of unknown function DUF1275 Mvan_1320 4 COG3619 COG3619, Predicted membrane protein Function unknown 120405977 Nonpathogen - hypothetical protein Mvan_5028 2 None None None 120401519 Common - transposase Mvan_0497 69 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 120406373 Common - hypothetical protein Mvan_5426 10 None None None 120401292 Common - dihydrodipicolinate reductase Mvan_0266 21 COG3804 COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase Function unknown 120404286 Common argD acetylornithine aminotransferase Mvan_3311 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 120404827 Common - hydrolases or acyltransferases (alpha/beta hydrolase superfamily)-like Mvan_3869 82 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120403980 Common - hypothetical protein Mvan_2998 1 None None None 120402004 Common - transcriptional regulator, TetR family Mvan_0989 10 COG1309 AcrR, Transcriptional regulator Transcription 120403172 Common - PII uridylyl-transferase Mvan_2180 123 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 120402620 Common - Transport protein Mvan_1614 75 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 120402339 Common - Aldehyde dehydrogenase (NAD(+)) Mvan_1328 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 120403772 Common - adenosylmethionine--8-amino-7-oxononanoate transaminase Mvan_2788 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 120401817 Common - 3-hydroxybutyryl-CoA dehydrogenase Mvan_0802 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 120404564 Common - luciferase family protein Mvan_3595 49 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120405472 Common - peptidase M15B and M15C, D,D-carboxypeptidase VanY/endolysins Mvan_4520 3 COG1876 VanY, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 120404783 Common - hypothetical protein Mvan_3825 4 None None None 120401941 Common - virulence factor Mce family protein Mvan_0926 15 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120404614 Nonpathogen - hypothetical protein Mvan_3648 2 None None None 120405295 Common - acyl-CoA synthetase Mvan_4341 217 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120406517 Common - glutamyl-Q tRNA(Asp) synthetase Mvan_5575 234 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 120402827 Common - protein of unknown function DUF81 Mvan_1828 50 COG0730 COG0730, Predicted permeases General function prediction only 120403324 Common - NLP/P60 protein Mvan_2333 101 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 120402936 Common - protein of unknown function DUF808 Mvan_1939 60 COG2354 COG2354, Uncharacterized protein conserved in bacteria Function unknown 120404670 Common - hypothetical protein Mvan_3708 14 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 120406624 Common - ribonuclease activity regulator protein RraA Mvan_5682 82 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 120403462 Common - TrkA-N domain protein Mvan_2472 136 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 120403761 Common dnaE DNA polymerase III subunit alpha Mvan_2777 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 120402071 Common - putative secreted protein Mvan_1056 1 None None None 120406622 Common - copper resistance D domain protein Mvan_5680 4 COG1276 PcoD, Putative copper export protein Inorganic ion transport and metabolism 120404611 Common - hypothetical protein Mvan_3643 1 None None None 120402909 Common - MscS Mechanosensitive ion channel Mvan_1912 180 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 120403268 Common - amino acid permease-associated region Mvan_2277 50 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 120404678 Common - Abortive infection protein Mvan_3716 28 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 120404236 Common - hypothetical protein Mvan_3260 2 None None None 120403131 Common - polyphosphate kinase Mvan_2139 162 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 120402615 Common - putative ammonia monooxygenase Mvan_1609 39 COG3180 AbrB, Putative ammonia monooxygenase General function prediction only 120406122 Common - integral membrane sensor signal transduction histidine kinase Mvan_5174 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 120401227 Common - hypothetical protein Mvan_0200 2 None None None 120401728 Common - putative ABC transporter membrane protein Mvan_0713 8 None None None 120401821 Common - protein of unknown function DUF445 Mvan_0806 49 COG2733 COG2733, Predicted membrane protein Function unknown 120405855 Common - ribonuclease H Mvan_4905 175 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 120405021 Common - hypothetical protein Mvan_4067 7 None None None 120406195 Nonpathogen - hypothetical protein Mvan_5247 5 None None None 120401823 Common - hypothetical protein Mvan_0808 4 COG1754 COG1754, Uncharacterized C-terminal domain of topoisomerase IA General function prediction only 120403143 Common - thiamine monophosphate kinase Mvan_2151 180 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 120404128 Common - Methyltransferase type 12 Mvan_3149 13 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 120402666 Common - RNA polymerase sigma factor SigF Mvan_1660 201 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 120403863 Common - transcriptional regulator, TetR family Mvan_2880 66 COG1309 AcrR, Transcriptional regulator Transcription 120403745 Common - hypothetical protein Mvan_2761 56 COG0398 COG0398, Uncharacterized conserved protein Function unknown 120405660 Common - protein of unknown function UPF0016 Mvan_4708 74 COG2119 COG2119, Predicted membrane protein Function unknown 120406676 Common - ABC transporter, periplasmic substrate-binding protein Mvan_5734 64 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 120405018 Common - hypothetical protein Mvan_4064 20 COG0753 KatE, Catalase Inorganic ion transport and metabolism 120403122 Nonpathogen - hypothetical protein Mvan_2130 3 None None None 120406612 Nonpathogen - putative phage repressor Mvan_5670 1 None None None 120405851 Common - Alcohol dehydrogenase GroES domain protein Mvan_4901 213 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 120406115 Common - luciferase family protein Mvan_5167 95 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120403264 Common - hypothetical protein Mvan_2273 1 None None None 120405166 Common - Carboxymuconolactone decarboxylase Mvan_4212 35 COG2128 COG2128, Uncharacterized conserved protein Function unknown 120406867 Common - fatty acid desaturase, type 2 Mvan_5927 10 None None None 120403333 Common - acyl-CoA dehydrogenase domain protein Mvan_2342 157 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120404717 Common - Propionyl-CoA carboxylase Mvan_3758 153 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 120401439 Common - PE domain protein Mvan_0414 1 None None None 120406251 Common - transcriptional regulator, TetR family Mvan_5303 20 COG1309 AcrR, Transcriptional regulator Transcription 120406206 Common - cytochrome P450 Mvan_5258 74 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120401783 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mvan_0768 64 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 120406434 Common - cobalamin synthesis CobW domain protein Mvan_5488 60 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 120406042 Common - protein tyrosine phosphatase Mvan_5094 132 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 120405514 Common - Na+/solute symporter Mvan_4562 153 COG4147 DhlC, Predicted symporter General function prediction only 120402994 Common - Thiolase Mvan_1999 100 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120403601 Common - hypothetical protein Mvan_2616 11 None None None 120405275 Common - transcriptional regulator, TetR family Mvan_4321 19 COG1309 AcrR, Transcriptional regulator Transcription 120403060 Nonpathogen - PE-PPE, C-terminal domain protein Mvan_2068 1 COG4547 CobT, Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase) Coenzyme metabolism 120401550 Common - putative nonspecific lipid-transfer protein Mvan_0529 89 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120401875 Common - hypothetical protein Mvan_0860 1 None None None 120405352 Common - virulence factor Mce family protein Mvan_4399 6 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120404974 Common - Inositol 2-dehydrogenase Mvan_4020 166 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 120406652 Nonpathogen - hypothetical protein Mvan_5710 1 None None None 120402714 Common - phosphoribosylaminoimidazole carboxylase ATPase subunit Mvan_1713 186 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 120406384 Common - Endoribonuclease L-PSP Mvan_5437 89 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 120402215 Common - hypothetical protein Mvan_1203 9 COG4766 EutQ, Ethanolamine utilization protein Amino acid transport and metabolism 120404855 Common - Integrase, catalytic region Mvan_3900 54 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 120405095 Common - cytochrome P450 Mvan_4141 88 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120402861 Common - regulatory protein, LuxR Mvan_1863 48 COG3899 COG3899, Predicted ATPase General function prediction only 120403326 Common - integral membrane sensor signal transduction histidine kinase Mvan_2335 211 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 120401065 Common - type I site-specific deoxyribonuclease, HsdR family Mvan_0037 136 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 120403846 Common - protein of unknown function DUF35 Mvan_2863 8 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 120405089 Common - AMP-dependent synthetase and ligase Mvan_4135 208 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120406174 Common - hypothetical protein Mvan_5226 5 None None None 120402154 Common - ribonuclease H Mvan_1142 7 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 120405298 Common - transcriptional regulator, MarR family Mvan_4344 70 COG1846 MarR, Transcriptional regulators Transcription 120401476 Common - hypothetical protein Mvan_0451 117 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 120402678 Nonpathogen - hypothetical protein Mvan_1672 1 None None None 120403619 Common - hypothetical protein Mvan_2634 15 None None None 120402799 Common - alpha/beta hydrolase fold Mvan_1800 51 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120402812 Common - PDZ/DHR/GLGF Mvan_1813 63 COG3480 SdrC, Predicted secreted protein containing a PDZ domain Signal transduction mechanisms 120402623 Common - transcriptional regulator, TetR family Mvan_1617 94 COG1309 AcrR, Transcriptional regulator Transcription 120404297 Common - acyl-CoA dehydrogenase domain protein Mvan_3323 154 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120406147 Common - virulence factor Mce family protein Mvan_5199 6 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120402831 Common - thioredoxin Mvan_1832 231 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 120402531 Common - hypothetical protein Mvan_1522 7 None None None 120402588 Common - Rieske (2Fe-2S) domain protein Mvan_1581 34 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 120403776 Common - transcriptional regulator, TetR family Mvan_2792 38 COG1309 AcrR, Transcriptional regulator Transcription 120401943 Common - Carboxymuconolactone decarboxylase Mvan_0928 21 COG2128 COG2128, Uncharacterized conserved protein Function unknown 120404387 Common - hypothetical protein Mvan_3414 4 None None None 120406456 Common - FAD dependent oxidoreductase Mvan_5513 78 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 120403551 Common - pyridoxine biosynthesis protein Mvan_2564 87 COG0214 SNZ1, Pyridoxine biosynthesis enzyme Coenzyme metabolism 120406085 Common - Oligopeptidase B Mvan_5137 106 COG1770 PtrB, Protease II Amino acid transport and metabolism 120401384 Common - hypothetical protein Mvan_0359 2 None None None 120402127 Common - phage integrase family protein Mvan_1113 218 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 120403425 Common dapF diaminopimelate epimerase Mvan_2435 196 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 120404705 Common - hypothetical protein Mvan_3746 9 None None None 120405307 Nonpathogen - hypothetical protein Mvan_4353 1 None None None 120403987 Common - 2-nitropropane dioxygenase, NPD Mvan_3005 29 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 120402650 Common - protein of unknown function DUF1338 Mvan_1644 23 COG5383 COG5383, Uncharacterized protein conserved in bacteria Function unknown 120404457 Common - SMP-30/Gluconolaconase/LRE domain protein Mvan_3485 5 None None None 120402306 Common - hypothetical protein Mvan_1295 6 None None None 120403129 Common - histone family protein DNA-binding protein Mvan_2137 191 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 120406467 Common - hypothetical protein Mvan_5524 2 None None None 120406748 Common - cobalamin B12-binding domain protein Mvan_5806 17 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 120406934 Nonpathogen - hypothetical protein Mvan_6002 2 None None None 120403606 Common - ABC transporter-related protein Mvan_2621 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 120402234 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mvan_1222 73 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 120401586 Common - Cupin 2, conserved barrel domain protein Mvan_0568 13 COG3435 COG3435, Gentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 120404439 Common - transcriptional regulator, TetR family Mvan_3467 10 COG1309 AcrR, Transcriptional regulator Transcription 120401379 Common - hypothetical protein Mvan_0354 2 None None None 120401547 Common - aromatic-ring-hydroxylating dioxygenase, beta subunit Mvan_0526 17 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 120401351 Common - alpha/beta hydrolase fold Mvan_0326 103 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120401723 Common - glycine oxidase ThiO Mvan_0708 117 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 120403723 Common - glycoside hydrolase, family 16 Mvan_2739 48 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 120401157 Common - cyclase/dehydrase Mvan_0129 5 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 120402533 Common - transcriptional regulator, MarR family Mvan_1524 127 COG1846 MarR, Transcriptional regulators Transcription 120406485 Common - hypothetical protein Mvan_5542 66 COG3285 COG3285, Predicted eukaryotic-type DNA primase DNA replication, recombination, and repair 120402494 Common - alpha/beta hydrolase fold Mvan_1485 119 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120405560 Common - transcriptional regulator, TetR family Mvan_4608 26 COG1309 AcrR, Transcriptional regulator Transcription 120406232 Common - short chain dehydrogenase Mvan_5284 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120401132 Common - putative methyltransferase Mvan_0104 24 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 120401780 Common - hypothetical protein Mvan_0765 5 None None None 120404449 Common - short chain dehydrogenase Mvan_3477 168 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 120403724 Common - thioredoxin Mvan_2740 231 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 120405933 Common - cytochrome P450 Mvan_4984 73 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120401160 Common - protein of unknown function DUF140 Mvan_0132 149 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 120402558 Common - hypothetical protein Mvan_1551 4 None None None 120405129 Common - cytochrome P450 Mvan_4175 68 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120405565 Common - putative adenylate/guanylate cyclase Mvan_4613 29 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 120402085 Common - hypothetical protein Mvan_1070 7 None None None 120406773 Common - putative transcriptional regulator, TetR family Mvan_5831 4 None None None 120401420 Common - anti-sigma-factor antagonist Mvan_0395 1 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 120401787 Common - protein of unknown function DUF344 Mvan_0772 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 120401576 Common - Ketopantoate reductase ApbA/PanE, N-terminal domain protein Mvan_0557 73 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 120402474 Common - hypothetical protein Mvan_1465 4 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 120405191 Common - short-chain dehydrogenase/reductase SDR Mvan_4237 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120403954 Common - protein of unknown function DUF899, thioredoxin family protein Mvan_2972 27 COG4312 COG4312, Uncharacterized protein conserved in bacteria Function unknown 120404442 Common hisG ATP phosphoribosyltransferase Mvan_3470 212 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 120406644 Common - protein of unknown function DUF427 Mvan_5702 54 COG2343 COG2343, Uncharacterized protein conserved in bacteria Function unknown 120405637 Common - LpqV Mvan_4685 1 None None None 120406544 Common - hypothetical protein Mvan_5602 1 COG5416 COG5416, Uncharacterized integral membrane protein Function unknown 120403156 Common - Vitamin K epoxide reductase Mvan_2164 16 COG4243 COG4243, Predicted membrane protein Function unknown 120401468 Common - iron-containing alcohol dehydrogenase Mvan_0443 215 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 120401117 Common - hypothetical protein Mvan_0089 1 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 120405210 Common - AMP-dependent synthetase and ligase Mvan_4256 221 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120406831 Common - transcriptional regulator, TetR family Mvan_5889 24 COG1309 AcrR, Transcriptional regulator Transcription 120403955 Common - transcriptional activator, TenA family Mvan_2973 76 COG0819 TenA, Putative transcription activator Transcription 120407007 Common rpmH 50S ribosomal protein L34 Mvan_6078 186 None None None 120401158 Common - transcriptional regulator, GntR family Mvan_0130 123 COG1802 GntR, Transcriptional regulators Transcription 120404924 Common - oxidoreductase domain protein Mvan_3970 121 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 120405505 Common - hypothetical protein Mvan_4553 3 None None None 120405122 Common - hypothetical protein Mvan_4168 1 None None None 120401502 Common - Tn554-related, transposase C Mvan_0480 8 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 120404231 Nonpathogen - hypothetical protein Mvan_3255 1 COG4683 COG4683, Uncharacterized protein conserved in bacteria Function unknown 120402459 Common - hypothetical protein Mvan_1449 1 None None None 120405190 Common - transcriptional regulator, TetR family Mvan_4236 28 COG1309 AcrR, Transcriptional regulator Transcription 120401526 Common - protein of unknown function DUF302 Mvan_0504 41 COG3439 COG3439, Uncharacterized conserved protein Function unknown 120405699 Common - Alcohol dehydrogenase GroES domain protein Mvan_4749 203 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 120401118 Nonpathogen - hypothetical protein Mvan_0090 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 120403105 Common - amino acid-binding ACT domain protein Mvan_2113 9 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 120405603 Common - polysaccharide deacetylase Mvan_4651 107 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 120405947 Common - Epoxide hydrolase domain protein Mvan_4998 60 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120405972 Common - transcriptional regulator, TetR family Mvan_5023 29 COG1309 AcrR, Transcriptional regulator Transcription 120403114 Common - acetolactate synthase 1 catalytic subunit Mvan_2122 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 120401831 Common - hypothetical protein Mvan_0816 4 COG4402 COG4402, Uncharacterized protein conserved in bacteria Function unknown 120402817 Common - Pyruvate, water dikinase Mvan_1818 135 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 120404773 Common - deoxyguanosinetriphosphate triphosphohydrolase-like protein Mvan_3815 159 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 120401323 Common - nitrite reductase (NAD(P)H), large subunit Mvan_0297 185 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 120402593 Common sdhA succinate dehydrogenase flavoprotein subunit Mvan_1587 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 120405821 Common - peptidase M23B Mvan_4871 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 120401632 Common - peptidase C26 Mvan_0616 134 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 120406805 Common - ATPase, P-type (transporting), HAD superfamily, subfamily IC Mvan_5863 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 120401197 Common - short-chain dehydrogenase/reductase SDR Mvan_0169 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120403279 Common - UbiC transcription regulator-associated domain protein Mvan_2288 131 COG2188 PhnF, Transcriptional regulators Transcription 120406793 Nonpathogen - hypothetical protein Mvan_5851 2 None None None 120404992 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Mvan_4038 6 None None None 120405840 Common - major facilitator superfamily MFS_1 Mvan_4890 111 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120404052 Common - Alcohol dehydrogenase GroES domain protein Mvan_3073 204 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 120406750 Common - NAD-dependent epimerase/dehydratase Mvan_5808 125 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 120405613 Common - hypothetical protein Mvan_4661 2 None None None 120406359 Common - regulatory protein, ArsR Mvan_5412 89 COG0640 ArsR, Predicted transcriptional regulators Transcription 120404274 Common - protein of unknown function DUF343 Mvan_3299 8 COG2835 COG2835, Uncharacterized conserved protein Function unknown 120402412 Common - putative signal-transduction protein with CBS domains Mvan_1401 159 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 120401858 Common - HAD-superfamily subfamily IB hydrolase, TIGR01490 Mvan_0843 103 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 120405483 Common - YceI family protein Mvan_4531 118 COG2353 COG2353, Uncharacterized conserved protein Function unknown 120401204 Common - protein of unknown function DUF77 Mvan_0176 19 COG0011 COG0011, Uncharacterized conserved protein Function unknown 120405042 Common - MaoC domain protein dehydratase Mvan_4088 76 COG2030 MaoC, Acyl dehydratase Lipid metabolism 120404720 Common - Alkylglycerone-phosphate synthase Mvan_3761 177 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 120406736 Nonpathogen - hypothetical protein Mvan_5794 4 None None None 120402042 Common - transcriptional regulator, LysR family Mvan_1027 191 COG0583 LysR, Transcriptional regulator Transcription 120403228 Common - SMP-30/Gluconolaconase/LRE domain protein Mvan_2237 82 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 120401237 Nonpathogen - hypothetical protein Mvan_0210 12 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 120404559 Common - transposase, mutator type Mvan_3590 80 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 120404984 Common - glutamine synthetase, catalytic region Mvan_4030 167 COG3968 COG3968, Uncharacterized protein related to glutamine synthetase General function prediction only 120401514 Common - Rieske (2Fe-2S) domain protein Mvan_0492 81 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 120401030 Common - DNA polymerase III subunit beta Mvan_0002 214 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 120402851 Common - peptidase C26 Mvan_1853 116 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 120401674 Common - ATPase AAA-2 domain protein Mvan_0659 218 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 120404547 Common - short chain dehydrogenase Mvan_3576 227 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 120406953 Common - binding-protein-dependent transport systems inner membrane component Mvan_6022 204 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 120402198 Common - Acetamidase/Formamidase Mvan_1186 65 COG2421 COG2421, Predicted acetamidase/formamidase Energy production and conversion 120403824 Common - response regulator receiver and ANTAR domain protein Mvan_2840 224 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 120402200 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Mvan_1188 6 None None None 120403659 Common - AMP-dependent synthetase and ligase Mvan_2675 194 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120401276 Common - hypothetical protein Mvan_0250 7 None None None 120402168 Common - transcriptional regulator, TetR family Mvan_1156 36 COG1309 AcrR, Transcriptional regulator Transcription 120404672 Common - Redoxin domain protein Mvan_3710 106 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 120402350 Common rpsE 30S ribosomal protein S5 Mvan_1339 243 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 120402475 Common - putative GAF sensor protein Mvan_1466 68 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 120405791 Common - molybdenum cofactor synthesis domain Mvan_4841 174 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 120403080 Common - NUDIX hydrolase Mvan_2088 33 None None None 120406767 Common - nitrile hydratase, alpha subunit Mvan_5825 21 None None None 120403004 Common - acyl-CoA synthetase Mvan_2010 213 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120406913 Nonpathogen - hypothetical protein Mvan_5980 1 None None None 120405147 Common - transcriptional regulator, TetR family Mvan_4193 94 COG1309 AcrR, Transcriptional regulator Transcription 120405066 Common - HoxW protein Mvan_4112 13 None None None 120406753 Common - iron-containing alcohol dehydrogenase Mvan_5811 168 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 120404427 Common - hypothetical protein Mvan_3455 6 None None None 120404579 Nonpathogen - hypothetical protein Mvan_3610 1 None None None 120402325 Common - ribosomal protein S17 Mvan_1314 227 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 120402926 Common - regulatory protein, LuxR Mvan_1929 95 COG3899 COG3899, Predicted ATPase General function prediction only 120406527 Common - dihydrodipicolinate reductase Mvan_5585 16 COG3804 COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase Function unknown 120403401 Common - hypothetical protein Mvan_2410 7 None None None 120401907 Nonpathogen - hypothetical protein Mvan_0892 2 None None None 120403612 Common - conserved hypothetical protein 341 Mvan_2627 22 COG1808 COG1808, Predicted membrane protein Function unknown 120406002 Common - hypothetical protein Mvan_5053 4 None None None 120401169 Common - RDD domain containing protein Mvan_0141 3 COG1714 COG1714, Predicted membrane protein/domain Function unknown 120405714 Common - alpha/beta hydrolase fold Mvan_4764 128 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120404729 Common - hypothetical protein Mvan_3770 4 None None None 120402377 Common - LpqN Mvan_1366 1 None None None 120405690 Common - hypothetical protein Mvan_4739 10 None None None 120402102 Common - Type IV secretory pathway VirB4 components-like Mvan_1088 14 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 120405995 Common - hypothetical protein Mvan_5046 42 COG3304 COG3304, Predicted membrane protein Function unknown 120406308 Common lysS lysyl-tRNA synthetase Mvan_5360 247 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 120406243 Common - ROK family protein Mvan_5295 122 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 120406460 Common - Methyltransferase type 11 Mvan_5517 181 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 120403497 Common - DNA binding domain, excisionase family Mvan_2509 1 None None None 120405557 Common - protein of unknown function DUF140 Mvan_4605 149 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 120402633 Common - Oxidoreductase FAD-binding domain protein Mvan_1627 120 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 120402343 Common - ribosomal protein L14 Mvan_1332 247 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 120405140 Common - ferredoxin Mvan_4186 150 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 120402356 Common - putative methyltransferase Mvan_1345 23 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 120403877 Common - Cyclohexanone monooxygenase Mvan_2894 72 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 120403185 Common - signal peptidase I Mvan_2193 181 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 120402840 Common - hypothetical protein Mvan_1842 79 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 120404187 Common - ferric uptake regulator, Fur family Mvan_3209 151 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 120406836 Common - glucose-methanol-choline oxidoreductase Mvan_5894 88 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 120405917 Common - AMP-dependent synthetase and ligase Mvan_4968 220 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120402213 Common - flavin-containing monooxygenase FMO Mvan_1201 77 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 120404434 Common - tRNA (adenine-N(1)-)-methyltransferase Mvan_3462 61 COG2519 GCD14, tRNA(1-methyladenosine) methyltransferase and related methyltransferases Translation, ribosomal structure and biogenesis 120406379 Common - Redoxin domain protein Mvan_5432 89 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 120404506 Common - GCN5-related N-acetyltransferase Mvan_3534 12 COG0456 RimI, Acetyltransferases General function prediction only 120401260 Common - short chain dehydrogenase Mvan_0234 232 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 120406198 Nonpathogen - hypothetical protein Mvan_5250 1 COG3944 COG3944, Capsular polysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 120401265 Common - hypothetical protein Mvan_0239 12 COG4319 COG4319, Ketosteroid isomerase homolog Function unknown 120403902 Common - amino acid permease-associated region Mvan_2919 63 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 120405075 Common - beta-lactamase domain protein Mvan_4121 137 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 120405897 Common - Cyclopropane-fatty-acyl-phospholipid synthase Mvan_4948 125 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 120406372 Common - acetyl-CoA synthetase Mvan_5425 217 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 120402221 Common - exodeoxyribonuclease V, beta subunit Mvan_1209 214 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 120401303 Common - hypothetical protein Mvan_0277 1 None None None 120401952 Common - O-succinylbenzoic acid--CoA ligase Mvan_0937 215 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120403913 Common - transcriptional modulator of MazE/toxin, MazF Mvan_2930 22 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 120405782 Common - molybdenum cofactor synthesis domain Mvan_4832 193 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 120402008 Common - heat shock protein HtpX Mvan_0993 192 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 120406701 Common - short-chain dehydrogenase/reductase SDR Mvan_5759 83 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120402132 Common - hypothetical protein Mvan_1119 2 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 120405712 Common - osmosensitive K+ channel signal transduction histidine kinase Mvan_4762 219 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 120401978 Common - Mammalian cell entry related domain protein Mvan_0963 13 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120406274 Common - ABC transporter-related protein Mvan_5326 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 120406868 Common - regulatory protein, LuxR Mvan_5928 88 COG3903 COG3903, Predicted ATPase General function prediction only 120404204 Common - cobalt transport protein Mvan_3226 38 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 120406121 Common - histidine triad (HIT) protein Mvan_5173 216 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 120406731 Common - hypothetical protein Mvan_5789 17 None None None 120402641 Common - Dyp-type peroxidase family Mvan_1635 25 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 120405704 Common - hypothetical protein Mvan_4754 10 None None None 120404483 Common - glutamine amidotransferase class-I Mvan_3511 111 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 120402271 Common - DNA-binding protein Mvan_1260 24 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 120405391 Common - putative lipoprotein LprC Mvan_4438 3 None None None 120405467 Common - dipeptidase Mvan_4515 197 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 120403979 Common - alpha/beta hydrolase fold Mvan_2997 41 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120404877 Common - hypothetical protein Mvan_3923 3 None None None 120406531 Common - PTS system, mannitol-specific IIC subunit Mvan_5589 75 COG2213 MtlA, Phosphotransferase system, mannitol-specific IIBC component Carbohydrate transport and metabolism 120402120 Nonpathogen - hypothetical protein Mvan_1106 1 None None None 120401123 Common - PfkB domain protein Mvan_0095 91 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 120403399 Common - hydrogenase assembly chaperone hypC/hupF Mvan_2408 41 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 120405910 Common - FAD dependent oxidoreductase Mvan_4961 50 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 120403015 Common - cytochrome P450 Mvan_2021 81 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120405381 Common - integral membrane sensor signal transduction histidine kinase Mvan_4428 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 120403335 Common - acyl-CoA synthetase Mvan_2344 215 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120404955 Common - flavin reductase domain protein, FMN-binding Mvan_4001 94 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 120405394 Common - ABC transporter, transmembrane region Mvan_4441 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 120405860 Common - Rieske (2Fe-2S) domain protein Mvan_4910 91 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 120403242 Common - hypothetical protein Mvan_2251 5 None None None 120401928 Common - biotin/lipoyl attachment domain-containing protein Mvan_0913 76 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 120403315 Common - hypothetical protein Mvan_2324 16 None None None 120401806 Common - protein of unknown function DUF779 Mvan_0791 41 COG3564 COG3564, Uncharacterized protein conserved in bacteria Function unknown 120404333 Common - Carotenoid oxygenase Mvan_3359 36 COG3670 COG3670, Lignostilbene-alpha,beta-dioxygenase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 120406505 Common - Glycerol dehydratase Mvan_5563 13 COG4909 PduC, Propanediol dehydratase, large subunit Secondary metabolites biosynthesis, transport, and catabolism 120403547 Common - CDP-alcohol phosphatidyltransferase Mvan_2560 65 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 120405326 Nonpathogen - hypothetical protein Mvan_4373 5 COG3889 COG3889, Predicted solute binding protein General function prediction only 120405580 Common - protein of unknown function DUF202 Mvan_4628 11 COG2149 COG2149, Predicted membrane protein Function unknown 120402175 Common - TetR-family transcriptional regulator Mvan_1163 27 None None None 120405803 Common - von Willebrand factor, type A Mvan_4853 20 COG4867 COG4867, Uncharacterized protein with a von Willebrand factor type A (vWA) domain General function prediction only 120402161 Nonpathogen - hypothetical protein Mvan_1149 1 None None None 120402141 Common - hypothetical protein Mvan_1128 2 None None None 120406522 Common - queuine tRNA-ribosyltransferase Mvan_5580 230 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 120403972 Common - type I phosphodiesterase/nucleotide pyrophosphatase Mvan_2990 26 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 120402514 Common - hypothetical protein Mvan_1505 15 None None None 120403485 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Mvan_2496 7 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 120402367 Common - transcriptional regulator, MarR family Mvan_1356 35 COG1846 MarR, Transcriptional regulators Transcription 120402013 Common - glycerophosphoryl diester phosphodiesterase Mvan_0998 126 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 120402825 Common - protein of unknown function DUF302 Mvan_1826 42 COG3439 COG3439, Uncharacterized conserved protein Function unknown 120403634 Common - hypothetical protein Mvan_2649 3 None None None 120402871 Common - NADH dehydrogenase subunit M Mvan_1873 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 120403510 Common - Integrase, catalytic region Mvan_2522 146 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 120406316 Common - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase Mvan_5368 188 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 120405888 Common - acetyl-CoA acetyltransferase Mvan_4939 106 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120406414 Common glpK glycerol kinase Mvan_5467 178 COG0554 GlpK, Glycerol kinase Energy production and conversion 120402068 Common - conserved hypothetical protein; putative glycosyltransferase Mvan_1053 20 None None None 120406083 Common - transcriptional regulator, TetR family Mvan_5135 68 COG1309 AcrR, Transcriptional regulator Transcription 120403358 Common - hydrogenase maturation protease Mvan_2367 58 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 120402657 Common - ATPase, P-type (transporting), HAD superfamily, subfamily IC Mvan_1651 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 120404695 Nonpathogen - hypothetical protein Mvan_3736 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 120403767 Common - threonine dehydratase Mvan_2783 222 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 120401871 Common - hypothetical protein Mvan_0856 1 None None None 120402119 Common - ADP-ribosylation/Crystallin J1 Mvan_1105 33 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 120401746 Common - GCN5-related N-acetyltransferase Mvan_0731 28 COG0456 RimI, Acetyltransferases General function prediction only 120402458 Common - Recombinase Mvan_1448 98 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 120404870 Nonpathogen - hypothetical protein Mvan_3916 1 None None None 120405798 Common - Propionyl-CoA carboxylase Mvan_4848 145 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 120401736 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mvan_0721 74 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 120406602 Common - hypothetical protein Mvan_5660 6 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 120403932 Common - beta-lactamase domain protein Mvan_2949 75 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 120405802 Common - protein of unknown function DUF1707 Mvan_4852 15 None None None 120401340 Common - alpha/beta hydrolase fold Mvan_0315 111 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120406410 Common - aldo/keto reductase Mvan_5463 172 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 120401284 Common - MaoC domain protein dehydratase Mvan_0258 31 COG2030 MaoC, Acyl dehydratase Lipid metabolism 120406967 Common - hypothetical protein Mvan_6037 9 None None None 120406212 Common - short chain dehydrogenase Mvan_5264 232 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120405038 Common - branched-chain alpha-keto acid dehydrogenase subunit E2 Mvan_4084 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 120406881 Common - phage integrase family protein Mvan_5943 195 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 120403567 Common yajC preprotein translocase subunit YajC Mvan_2582 16 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 120406266 Common - ABC-3 protein Mvan_5318 197 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 120401363 Common - NAD-dependent epimerase/dehydratase Mvan_0338 151 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 120401461 Common - binding-protein-dependent transport systems inner membrane component Mvan_0436 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 120403895 Common - alpha/beta hydrolase fold Mvan_2912 192 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120404253 Common - chromosome segregation and condensation protein ScpA Mvan_3278 118 COG1354 COG1354, Uncharacterized conserved protein Function unknown 120403441 Common - RNA polymerase sigma factor SigB Mvan_2451 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 120402139 Common - L-carnitine dehydratase/bile acid-inducible protein F Mvan_1126 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 120401427 Nonpathogen - hypothetical protein Mvan_0402 1 None None None 120403420 Common - putative conserved transmembrane protein Mvan_2430 5 None None None 120402973 Common - Butyryl-CoA dehydrogenase Mvan_1977 165 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120402406 Common - GAF sensor signal transduction histidine kinase Mvan_1395 137 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 120406499 Common - cytochrome c biogenesis protein, transmembrane region Mvan_5557 21 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 120401406 Common - cob(II)yrinic acid a,c-diamide reductase Mvan_0381 100 COG0778 NfnB, Nitroreductase Energy production and conversion 120403434 Common - phenazine biosynthesis protein PhzF family Mvan_2444 64 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 120401559 Common - alpha/beta hydrolase fold Mvan_0538 154 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120403586 Common - acyl-CoA dehydrogenase domain protein Mvan_2601 115 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120406240 Common - ABC transporter-related protein Mvan_5292 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 120406300 Common - Antibiotic biosynthesis monooxygenase Mvan_5352 18 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 120406445 Common - hypothetical protein Mvan_5502 5 None None None 120403366 Common - tetratricopeptide TPR_2 Mvan_2375 11 None None None 120404898 Common obgE GTPase ObgE Mvan_3944 249 COG0536 Obg, Predicted GTPase General function prediction only 120406257 Common - ferredoxin Mvan_5309 132 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 120406261 Common - HAD-superfamily hydrolase, subfamily IIB Mvan_5313 62 COG1877 OtsB, Trehalose-6-phosphatase Carbohydrate transport and metabolism 120401214 Common - hypothetical protein Mvan_0187 1 None None None 120403297 Common - major facilitator superfamily MFS_1 Mvan_2306 191 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120403028 Common - short chain dehydrogenase Mvan_2034 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 120403035 Common nrdI ribonucleotide reductase stimulatory protein Mvan_2041 36 COG1780 NrdI, Protein involved in ribonucleotide reduction Nucleotide transport and metabolism 120403193 Common - hypothetical protein Mvan_2202 157 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 120405280 Common - hypothetical protein Mvan_4326 10 None None None 120402370 Common - Haloacid dehalogenase domain protein hydrolase Mvan_1359 29 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 120403042 Common - hypothetical protein Mvan_2048 2 None None None 120406718 Common - hypothetical protein Mvan_5776 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 120406183 Common - acetaldehyde dehydrogenase Mvan_5235 37 COG4569 MhpF, Acetaldehyde dehydrogenase (acetylating) Secondary metabolites biosynthesis, transport, and catabolism 120406558 Common - cysteine desulfurase family protein Mvan_5616 182 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 120402020 Common - protein of unknown function DUF214 Mvan_1005 79 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 120404357 Common - permease for cytosine/purines, uracil, thiamine, allantoin Mvan_3383 29 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 120405867 Common - Ku domain protein Mvan_4917 63 COG1273 COG1273, Uncharacterized conserved protein Function unknown 120402951 Common - Integrase, catalytic region Mvan_1955 145 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 120403593 Common - protein of unknown function, zinc metallopeptidase putative Mvan_2608 86 COG2321 COG2321, Predicted metalloprotease General function prediction only 120406561 Common - glycosyl transferase, family 2 Mvan_5619 11 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 120406872 Common - hypothetical protein Mvan_5932 55 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 120405601 Common fumC fumarate hydratase Mvan_4649 239 COG0114 FumC, Fumarase Energy production and conversion 120406462 Common - DNA polymerase III subunit epsilon Mvan_5519 164 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 120402140 Common - protein of unknown function DUF732 Mvan_1127 1 None None None 120406491 Nonpathogen - hypothetical protein Mvan_5548 1 None None None 120401480 Common - phage integrase family protein Mvan_0455 215 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 120404737 Common - protein of unknown function DUF222 Mvan_3778 6 None None None 120403505 Nonpathogen - hypothetical protein Mvan_2517 1 None None None 120403702 Common - glucose-6-phosphate 1-dehydrogenase Mvan_2718 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 120405734 Common - arsenate reductase Mvan_4784 98 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 120402581 Common - amino acid permease-associated region Mvan_1574 112 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 120402444 Common rpsM 30S ribosomal protein S13 Mvan_1433 246 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 120406724 Nonpathogen - hypothetical protein Mvan_5782 1 None None None 120403305 Common infB translation initiation factor IF-2 Mvan_2314 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 120404599 Common - hypothetical protein Mvan_3631 5 None None None 120401040 Common - cytochrome P450 Mvan_0012 78 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120401311 Common - transposase, IS4 family protein Mvan_0285 57 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 120404834 Common - hypothetical protein Mvan_3876 2 None None None 120403078 Common frcK putative fructose transport system kinase Mvan_2086 38 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 120402795 Common - hypothetical protein Mvan_1796 8 None None None 120402603 Common - PE-PPE, C-terminal domain protein Mvan_1597 34 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 120405587 Common - 3-beta hydroxysteroid dehydrogenase/isomerase Mvan_4635 210 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 120406249 Common - transcriptional regulator, LysR family Mvan_5301 108 COG0583 LysR, Transcriptional regulator Transcription 120403592 Common - protein of unknown function DUF885 Mvan_2607 41 COG4805 COG4805, Uncharacterized protein conserved in bacteria Function unknown 120404303 Common - hypothetical protein Mvan_3329 9 None None None 120404225 Nonpathogen - hypothetical protein Mvan_3248 1 None None None 120401707 Common - protein of unknown function DUF899, thioredoxin family protein Mvan_0692 26 COG4312 COG4312, Uncharacterized protein conserved in bacteria Function unknown 120405359 Common - monooxygenase, FAD-binding Mvan_4406 68 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 120401339 Common - metal-dependent hydrolase Mvan_0314 25 COG3687 COG3687, Predicted metal-dependent hydrolase General function prediction only 120402547 Common - protein of unknown function, ATP binding Mvan_1539 31 COG2229 COG2229, Predicted GTPase General function prediction only 120405838 Common - ROK family protein Mvan_4888 153 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 120405289 Common - hypothetical protein Mvan_4335 1 None None None 120406368 Common - type II secretion system protein E Mvan_5421 151 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 120401450 Common - Trans-aconitate 2-methyltransferase Mvan_0425 51 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 120403219 Common - aminoglycoside phosphotransferase Mvan_2228 11 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 120404135 Common - 4-hydroxyphenylacetate 3-hydroxylase Mvan_3156 49 COG2368 COG2368, Aromatic ring hydroxylase Secondary metabolites biosynthesis, transport, and catabolism 120406259 Common - acyl-CoA dehydrogenase domain protein Mvan_5311 134 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120405989 Common - major facilitator superfamily MFS_1 Mvan_5040 9 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 120406295 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Mvan_5347 43 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 120401624 Common - protein of unknown function DUF1116 Mvan_0608 17 None None None 120403163 Common rnc ribonuclease III Mvan_2171 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 120404846 Common - hypothetical protein Mvan_3890 1 None None None 120401096 Common - conserved hypothetical alanine rich protein Mvan_0068 1 None None None 120401686 Common - hypothetical protein Mvan_0671 3 None None None 120405176 Common - short-chain dehydrogenase/reductase SDR Mvan_4222 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120401990 Common - 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase Mvan_0975 90 COG1165 MenD, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase Coenzyme metabolism 120402940 Common - hypothetical protein Mvan_1943 44 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 120402316 Common rplC 50S ribosomal protein L3 Mvan_1305 239 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 120404730 Common - dihydrodipicolinate reductase Mvan_3771 24 COG3804 COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase Function unknown 120403217 Common - aldehyde dehydrogenase Mvan_2226 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 120404476 Common - response regulator receiver and unknown domain protein Mvan_3504 224 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 120402265 Common rplL 50S ribosomal protein L7/L12 Mvan_1253 215 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 120402764 Common - choline/carnitine/betaine transporter Mvan_1765 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 120403754 Common - RNA-binding S4 domain protein Mvan_2770 48 COG2501 COG2501, Uncharacterized conserved protein Function unknown 120404915 Common - Transglycosylase domain protein Mvan_3961 12 None None None 120401435 Common - hypothetical protein Mvan_0410 11 COG3662 COG3662, Uncharacterized protein conserved in bacteria Function unknown 120403685 Common - lipase, class 2 Mvan_2701 16 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 120405652 Common - anti-sigma-factor antagonist Mvan_4700 1 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 120406234 Common - acyl-CoA synthetase Mvan_5286 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120405678 Nonpathogen - hypothetical protein Mvan_4727 1 None None None 120402401 Common - ornithine carbamoyltransferase Mvan_1390 239 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 120404888 Common proA gamma-glutamyl phosphate reductase Mvan_3934 187 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 120405101 Common - virulence factor Mce family protein Mvan_4147 16 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120401598 Common - transposase, mutator type Mvan_0581 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 120404417 Common - protein of unknown function DUF245 domain protein Mvan_3445 16 None None None 120403852 Common - Rieske (2Fe-2S) domain protein Mvan_2869 83 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 120404281 Nonpathogen - hypothetical protein Mvan_3306 1 None None None 120401568 Common - aromatic-ring-hydroxylating dioxygenase, beta subunit Mvan_0547 19 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 120402122 Nonpathogen - hypothetical protein Mvan_1108 1 None None None 120406063 Common - hypothetical protein Mvan_5115 18 None None None 120404912 Common - ferredoxin Mvan_3958 101 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 120405459 Common - hypothetical protein Mvan_4507 4 None None None 120404121 Common - binding-protein-dependent transport systems inner membrane component Mvan_3142 132 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 120406556 Common - transcriptional regulator, MarR family Mvan_5614 26 COG1846 MarR, Transcriptional regulators Transcription 120406887 Common - CHAP domain containing protein Mvan_5951 5 COG3942 COG3942, Surface antigen General function prediction only 120401378 Common - AMP-dependent synthetase and ligase Mvan_0353 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120406993 Common - integral membrane protein MviN Mvan_6064 126 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 120404514 Common - hypothetical protein Mvan_3542 7 None None None 120402076 Common - short chain dehydrogenase Mvan_1061 73 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120405968 Common - hypothetical protein Mvan_5019 31 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 120403299 Common - prolyl-tRNA synthetase Mvan_2308 231 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 120403588 Common - transcriptional regulator, TetR family Mvan_2603 13 COG1309 AcrR, Transcriptional regulator Transcription 120405181 Common - NAD-dependent epimerase/dehydratase Mvan_4227 4 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 120402725 Common - hypothetical protein Mvan_1725 14 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 120403051 Common - hypothetical protein Mvan_2057 4 None None None 120401968 Common - acyl-CoA synthetase Mvan_0953 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120404147 Common - hypothetical protein Mvan_3168 5 None None None 120406656 Common - transcriptional regulator, TetR family Mvan_5714 3 COG1309 AcrR, Transcriptional regulator Transcription 120404261 Nonpathogen - Glyoxalase/bleomycin resistance protein/dioxygenase Mvan_3286 8 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 120405671 Common - protein of unknown function DUF427 Mvan_4720 41 COG2343 COG2343, Uncharacterized protein conserved in bacteria Function unknown 120405245 Common - cysteine synthases Mvan_4291 221 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 120404622 Common - response regulator receiver protein Mvan_3657 123 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 120402643 Nonpathogen - hypothetical protein Mvan_1637 1 None None None 120406857 Common - transcriptional regulator, TetR family Mvan_5917 110 COG1309 AcrR, Transcriptional regulator Transcription 120404533 Common - putative conserved membrane protein MmpS3 Mvan_3562 1 COG5373 COG5373, Predicted membrane protein Function unknown 120403348 Common - hydrogenase accessory protein HypB Mvan_2357 108 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 120405759 Common - glycosyl transferase, family 39 Mvan_4809 32 COG1928 PMT1, Dolichyl-phosphate-mannose--protein O-mannosyl transferase Posttranslational modification, protein turnover, chaperones 120401070 Common - purine catabolism PurC domain protein Mvan_0042 27 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 120402902 Common - glycosyltransferase, MGT family Mvan_1905 51 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 120402255 Common - hypothetical protein Mvan_1243 23 COG3662 COG3662, Uncharacterized protein conserved in bacteria Function unknown 120406017 Common - NADH:flavin oxidoreductase/NADH oxidase Mvan_5069 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 120401616 Common - cytochrome P450 Mvan_0600 87 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120402108 Common - Integrase, catalytic region Mvan_1094 135 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 120401759 Common - putative monovalent cation/H+ antiporter subunit A Mvan_0744 208 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 120405831 Common - short chain dehydrogenase Mvan_4881 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 120401077 Common - protein of unknown function DUF1023 Mvan_0049 9 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 120401408 Common - amidohydrolase 2 Mvan_0383 17 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 120405188 Common - cytochrome P450 Mvan_4234 74 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120403803 Common - prolipoprotein diacylglyceryl transferase Mvan_2819 199 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 120404597 Common - diguanylate cyclase with PAS/PAC sensor Mvan_3629 185 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 120402240 Common - beta-lactamase domain protein Mvan_1228 221 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 120406391 Common - Pyridoxal-5'-phosphate-dependent enzyme, beta subunit Mvan_5444 208 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 120403816 Common - extracellular solute-binding protein, family 3 Mvan_2832 150 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 120406714 Common - protein of unknown function UPF0061 Mvan_5772 110 COG0397 COG0397, Uncharacterized conserved protein Function unknown 120402524 Common - two component transcriptional regulator, LuxR family Mvan_1515 125 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 120405056 Common - ErfK/YbiS/YcfS/YnhG family protein Mvan_4102 20 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 120402188 Common - hypothetical protein Mvan_1176 35 COG4291 COG4291, Predicted membrane protein Function unknown 120406280 Common - cobalamin synthesis CobW domain protein Mvan_5332 58 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 120403291 Common - malate:quinone oxidoreductase Mvan_2300 54 COG0579 COG0579, Predicted dehydrogenase General function prediction only 120402732 Common - F420-0--gamma-glutamyl ligase Mvan_1732 52 COG1478 COG1478, Uncharacterized conserved protein Function unknown 120406369 Common - hypothetical protein Mvan_5422 14 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 120406362 Nonpathogen - hypothetical protein Mvan_5415 1 None None None 120405736 Common - short-chain dehydrogenase/reductase SDR Mvan_4786 175 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120404654 Common - protein of unknown function DUF305 Mvan_3691 32 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 120403008 Common - hypothetical protein Mvan_2014 2 None None None 120402708 Common - membrane-flanked domain Mvan_1707 18 COG3428 COG3428, Predicted membrane protein Function unknown 120403503 Nonpathogen - transcription factor WhiB Mvan_2515 1 None None None 120403917 Common - Helix-turn-helix, type 11 domain protein Mvan_2934 101 COG2378 COG2378, Predicted transcriptional regulator Transcription 120405443 Common - transposase, IS111A/IS1328/IS1533 Mvan_4491 44 None None None 120402177 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mvan_1165 134 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 120406398 Common - hypothetical protein Mvan_5451 12 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 120402632 Common - transcriptional regulator, TetR family Mvan_1626 67 COG1309 AcrR, Transcriptional regulator Transcription 120401847 Common - hypothetical protein Mvan_0832 9 None None None 120405253 Common - LpqM Mvan_4299 18 COG2321 COG2321, Predicted metalloprotease General function prediction only 120404666 Common - Cytochrome-c oxidase Mvan_3704 167 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 120404108 Common - acyl-CoA synthetase Mvan_3129 206 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120405013 Nonpathogen - hypothetical protein Mvan_4059 1 None None None 120401225 Common trmB tRNA (guanine-N(7))-methyltransferase Mvan_0198 179 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 120402586 Common - Squalene/phytoene synthase Mvan_1579 107 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 120404715 Common - 3-oxoacyl-(acyl carrier protein) synthase II Mvan_3756 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120405702 Common - hypothetical protein Mvan_4752 66 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 120403233 Common - short-chain dehydrogenase/reductase SDR Mvan_2242 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120404093 Nonpathogen - hypothetical protein Mvan_3114 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 120404648 Common - helix-turn-helix- domain containing protein, AraC type Mvan_3684 38 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 120405519 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Mvan_4567 10 COG3871 COG3871, Uncharacterized stress protein (general stress protein 26) General function prediction only 120403245 Common - hypothetical protein Mvan_2254 1 None None None 120403969 Common - response regulator receiver protein Mvan_2987 193 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 120403970 Common - multi-sensor signal transduction histidine kinase Mvan_2988 222 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 120402680 Common - Maf-like protein Mvan_1674 157 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 120401785 Common - phosphoesterase, PA-phosphatase related Mvan_0770 1 None None None 120406843 Common - transcriptional regulator, TetR family Mvan_5902 23 COG1309 AcrR, Transcriptional regulator Transcription 120402945 Common - CrcB protein Mvan_1948 2 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 120404658 Nonpathogen - hypothetical protein Mvan_3696 1 COG3462 COG3462, Predicted membrane protein Function unknown 120401930 Common - 3-hydroxyacyl-CoA dehydrogenase, NAD-binding Mvan_0915 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 120402040 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Mvan_1025 224 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 120403994 Common - cytochrome P450 Mvan_3012 73 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120405507 Common - Resolvase, N-terminal domain Mvan_4555 95 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 120404379 Common - hypothetical protein Mvan_3406 79 COG1742 COG1742, Uncharacterized conserved protein Function unknown 120404965 Common - periplasmic binding protein/LacI transcriptional regulator Mvan_4011 80 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 120406685 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Mvan_5743 8 None None None 120401449 Common - amidohydrolase 2 Mvan_0424 29 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 120404767 Common - LppP Mvan_3809 1 None None None 120405781 Common - GCN5-related N-acetyltransferase Mvan_4831 78 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 120405226 Common - transcriptional regulator, TetR family Mvan_4272 47 COG1309 AcrR, Transcriptional regulator Transcription 120406189 Common - FHA domain containing protein Mvan_5241 1 None None None 120404011 Nonpathogen - hypothetical protein Mvan_3031 1 COG5183 SSM4, Protein involved in mRNA turnover and stability RNA processing and modification 120405727 Common - transcription-repair coupling factor Mvan_4777 227 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 120403276 Nonpathogen - hypothetical protein Mvan_2285 1 None None None 120401657 Common - transcriptional regulator, TetR family Mvan_0641 25 COG1309 AcrR, Transcriptional regulator Transcription 120402039 Common - extracellular solute-binding protein, family 5 Mvan_1024 191 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 120401752 Common - peptidase S16, lon domain protein Mvan_0737 72 COG2802 COG2802, Uncharacterized protein, similar to the N-terminal domain of Lon protease General function prediction only 120401051 Common - protein kinase Mvan_0023 159 COG2815 COG2815, Uncharacterized protein conserved in bacteria Function unknown 120405264 Common - hypothetical protein Mvan_4310 3 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 120405370 Common - Rieske (2Fe-2S) domain protein Mvan_4417 32 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 120405665 Common - hypothetical protein Mvan_4714 2 None None None 120403412 Common - hypothetical protein Mvan_2422 122 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 120406680 Common - orotate phosphoribosyltransferase Mvan_5738 164 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 120403632 Common aroB 3-dehydroquinate synthase Mvan_2647 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 120401771 Common - HAD-superfamily hydrolase, subfamily IIA Mvan_0756 104 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 120404394 Common fxsA FxsA Mvan_3421 1 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 120403545 Common thrS threonyl-tRNA synthetase Mvan_2558 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 120403739 Common - cyanate hydratase Mvan_2755 41 COG1513 CynS, Cyanate lyase Inorganic ion transport and metabolism 120403384 Common - cell divisionFtsK/SpoIIIE Mvan_2393 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 120402057 Common - glycosyl transferase, group 1 Mvan_1042 97 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 120404680 Common - transposase IS3/IS911 family protein Mvan_3719 56 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 120406341 Common - hypothetical protein Mvan_5393 5 COG2442 COG2442, Uncharacterized conserved protein Function unknown 120402556 Common - NADH:flavin oxidoreductase/NADH oxidase Mvan_1549 179 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 120404630 Common - hypothetical protein Mvan_3666 6 None None None 120406065 Common - Abortive infection protein Mvan_5117 3 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 120405623 Common - acyl-CoA dehydrogenase domain protein Mvan_4671 157 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120405683 Common - protein of unknown function DUF1348 Mvan_4732 49 COG3558 COG3558, Uncharacterized protein conserved in bacteria Function unknown 120401825 Common - hypothetical protein Mvan_0810 3 None None None 120405929 Common - dihydrodipicolinate reductase Mvan_4980 23 COG3804 COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase Function unknown 120406407 Common - Carotenoid oxygenase Mvan_5460 35 COG3670 COG3670, Lignostilbene-alpha,beta-dioxygenase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 120405842 Common - 3-oxoacid CoA-transferase, B subunit Mvan_4892 92 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 120401191 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mvan_0163 26 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 120406354 Common - type II secretion system protein Mvan_5406 4 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 120405156 Common - Alcohol dehydrogenase, zinc-binding domain protein Mvan_4202 157 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 120402676 Common - acyltransferase 3 Mvan_1670 76 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 120405649 Common - signal transduction histidine kinase regulating citrate/malate metabolism Mvan_4697 135 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 120401246 Common - regulatory protein GntR, HTH Mvan_0220 112 COG2188 PhnF, Transcriptional regulators Transcription 120406579 Common - hypothetical protein Mvan_5637 2 None None None 120403930 Common - putative conserved integral membrane protein Mvan_2947 19 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 120406515 Common - short chain dehydrogenase Mvan_5573 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120405471 Common - putative transferase Mvan_4519 35 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 120405751 Common - Transglycosylase domain protein Mvan_4801 23 COG3583 COG3583, Uncharacterized protein conserved in bacteria Function unknown 120405278 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Mvan_4324 218 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 120406796 Common - ErfK/YbiS/YcfS/YnhG family protein Mvan_5854 21 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 120403536 Common - two component transcriptional regulator, LuxR family Mvan_2548 206 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 120401054 Common - cell cycle protein Mvan_0026 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 120406616 Common - hypothetical protein Mvan_5674 2 None None None 120405534 Common - Abortive infection protein Mvan_4582 5 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 120401961 Common - helix-turn-helix- domain containing protein, AraC type Mvan_0946 124 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 120402487 Common - luciferase family protein Mvan_1478 74 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120401808 Nonpathogen - hypothetical protein Mvan_0793 1 None None None 120405615 Common - channel protein, hemolysin III family Mvan_4663 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 120404464 Common - nitrite transporter Mvan_3492 84 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 120406314 Common - hypothetical protein Mvan_5366 3 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 120405891 Common - isochorismatase hydrolase Mvan_4942 106 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 120403638 Nonpathogen - hypothetical protein Mvan_2653 2 None None None 120406632 Common - hypothetical protein Mvan_5690 1 None None None 120401512 Common - Alcohol dehydrogenase GroES domain protein Mvan_0490 214 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 120404639 Common - integral membrane sensor signal transduction histidine kinase Mvan_3675 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 120401250 Common - Amidohydrolase 3 Mvan_0224 41 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 120403340 Common rpsO 30S ribosomal protein S15 Mvan_2349 214 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 120404629 Common - putative ABC transporter membrane protein Mvan_3665 4 None None None 120404246 Common - protein of unknown function DUF81 Mvan_3271 26 COG0730 COG0730, Predicted permeases General function prediction only 120403436 Common - protein of unknown function DUF75 Mvan_2446 20 COG2047 COG2047, Uncharacterized protein (ATP-grasp superfamily) General function prediction only 120405778 Nonpathogen - hypothetical protein Mvan_4828 1 None None None 120401868 Nonpathogen - hypothetical protein Mvan_0853 1 None None None 120401257 Common - Alpha/beta hydrolase fold-3 domain protein Mvan_0231 63 COG0657 Aes, Esterase/lipase Lipid metabolism 120406287 Common ispF 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Mvan_5339 187 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 120406945 Nonpathogen - hypothetical protein Mvan_6013 1 COG3319 COG3319, Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases Secondary metabolites biosynthesis, transport, and catabolism 120402492 Common - glutamate decarboxylase Mvan_1483 67 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 120406138 Common - enoyl-CoA hydratase Mvan_5190 176 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120403872 Common - regulatory proteins, IclR Mvan_2889 120 COG1414 IclR, Transcriptional regulator Transcription 120405341 Common - amine oxidase Mvan_4388 65 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 120403223 Common - transcriptional regulator, TetR family Mvan_2232 3 COG1309 AcrR, Transcriptional regulator Transcription 120403960 Common - O-succinylbenzoate-CoA synthase Mvan_2978 13 None None None 120401561 Common - aromatic-ring-hydroxylating dioxygenase, beta subunit Mvan_0540 17 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 120403294 Common - cob(I)yrinic acid a,c-diamide adenosyltransferase Mvan_2303 141 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 120403785 Nonpathogen - putative alanine and proline rich membrane protein Mvan_2801 1 None None None 120405111 Common - short-chain dehydrogenase/reductase SDR Mvan_4157 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120403475 Common - Orn/DAP/Arg decarboxylase 2 Mvan_2486 24 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 120406113 Common - nuclear transport factor 2 Mvan_5165 6 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 120406977 Common - polar amino acid ABC transporter, inner membrane subunit Mvan_6047 176 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 120401815 Common - acyl-ACP thioesterase Mvan_0800 3 COG3884 FatA, Acyl-ACP thioesterase Lipid metabolism 120404616 Common - ErfK/YbiS/YcfS/YnhG family protein Mvan_3651 19 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 120404604 Common - hypothetical protein Mvan_3636 9 COG3462 COG3462, Predicted membrane protein Function unknown 120403174 Common - amidohydrolase Mvan_2182 74 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 120403868 Common - Stress responsive alpha-beta barrel domain protein Mvan_2885 6 None None None 120404054 Common - Fibronectin-attachment family protein Mvan_3075 1 COG5373 COG5373, Predicted membrane protein Function unknown 120405248 Common - peptidase S58, DmpA Mvan_4294 51 COG3191 DmpA, L-aminopeptidase/D-esterase Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120406605 Common - hypothetical protein Mvan_5663 7 None None None 120403948 Common - acyl-CoA synthetase Mvan_2966 186 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120406642 Common - Ferritin, Dps family protein Mvan_5700 106 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 120404295 Common - putative adenylate/guanylate cyclase Mvan_3321 54 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 120403472 Common - protoporphyrinogen oxidase Mvan_2482 54 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 120404781 Common recO DNA repair protein RecO Mvan_3823 66 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 120405123 Common - Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit Mvan_4169 160 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 120401486 Common - regulatory proteins, IclR Mvan_0462 120 COG1414 IclR, Transcriptional regulator Transcription 120404808 Common - AMP-dependent synthetase and ligase Mvan_3850 221 COG1021 EntE, Peptide arylation enzymes Secondary metabolites biosynthesis, transport, and catabolism 120403147 Common - ATP-dependent DNA helicase RecG Mvan_2155 213 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 120402073 Common - hypothetical protein Mvan_1058 1 None None None 120404076 Common - malate synthase G Mvan_3097 69 COG2225 AceB, Malate synthase Energy production and conversion 120404605 Nonpathogen - hypothetical protein Mvan_3637 2 COG4454 COG4454, Uncharacterized copper-binding protein Inorganic ion transport and metabolism 120406328 Common - D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase Mvan_5380 97 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 120401521 Common - protein of unknown function DUF140 Mvan_0499 63 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 120404402 Common cobH precorrin-8X methylmutase Mvan_3430 118 COG2082 CobH, Precorrin isomerase Coenzyme metabolism 120404234 Nonpathogen - hypothetical protein Mvan_3258 1 COG5180 PBP1, Protein interacting with poly(A)-binding protein RNA processing and modification 120405970 Common - drug resistance transporter, EmrB/QacA subfamily Mvan_5021 226 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120402348 Common rplF 50S ribosomal protein L6 Mvan_1337 244 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 120403771 Common - acyltransferase 3 Mvan_2787 68 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 120406639 Common gltD glutamate synthase subunit beta Mvan_5697 201 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 120406678 Common - hypothetical protein Mvan_5736 1 None None None 120403062 Nonpathogen - hypothetical protein Mvan_2070 1 COG3967 DltE, Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) Cell envelope biogenesis, outer membrane 120406104 Common - short chain dehydrogenase Mvan_5156 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120406614 Common - hypothetical protein Mvan_5672 3 None None None 120405979 Common - glycoside hydrolase, family 1 Mvan_5030 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 120403120 Common - D-3-phosphoglycerate dehydrogenase Mvan_2128 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 120404289 Common argC N-acetyl-gamma-glutamyl-phosphate reductase Mvan_3314 214 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 120402337 Common - Rieske (2Fe-2S) domain protein Mvan_1326 70 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 120405271 Common - cytochrome P450 Mvan_4317 82 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120405938 Common - ATPase, P-type (transporting), HAD superfamily, subfamily IC Mvan_4989 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 120401984 Common - transcriptional regulator, TetR family Mvan_0969 4 COG1309 AcrR, Transcriptional regulator Transcription 120404469 Common - hypothetical protein Mvan_3497 17 COG3687 COG3687, Predicted metal-dependent hydrolase General function prediction only 120401032 Common recF recombination protein F Mvan_0004 165 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 120402820 Common - transcriptional regulator, TetR family Mvan_1821 2 COG1309 AcrR, Transcriptional regulator Transcription 120402649 Common - aldehyde dehydrogenase Mvan_1643 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 120401478 Common - transposase IS3/IS911 Mvan_0453 8 None None None 120401176 Common - transcriptional regulator, MarR family Mvan_0148 16 COG1846 MarR, Transcriptional regulators Transcription 120404164 Common - nuclear transport factor 2 Mvan_3185 3 None None None 120402252 Common - alpha/beta hydrolase fold Mvan_1240 41 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120403145 Common rpmB 50S ribosomal protein L28 Mvan_2153 36 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 120404455 Common - undecaprenyl pyrophosphate phosphatase Mvan_3483 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 120404698 Common - transposase IS3/IS911 family protein Mvan_3739 56 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 120405853 Nonpathogen - hypothetical protein Mvan_4903 1 None None None 120404549 Common - hypothetical protein Mvan_3578 7 None None None 120403396 Common - hydrogenase expression/formation protein HypD Mvan_2405 109 COG0409 HypD, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 120406180 Common - hypothetical protein Mvan_5232 1 None None None 120402460 Common - hypothetical protein Mvan_1450 7 None None None 120403861 Common - Betaine-aldehyde dehydrogenase Mvan_2878 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 120402893 Common - L-carnitine dehydratase/bile acid-inducible protein F Mvan_1895 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 120403985 Common - anti-sigma-factor antagonist Mvan_3003 28 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 120406040 Common - phosphate ABC transporter, periplasmic phosphate-binding protein Mvan_5092 105 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 120402181 Common - transcriptional regulator, TetR family Mvan_1169 61 COG1309 AcrR, Transcriptional regulator Transcription 120403096 Common - phospholipid/glycerol acyltransferase Mvan_2104 67 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 120405512 Common - response regulator receiver protein Mvan_4560 187 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 120401456 Common - putative conserved exported protein Mvan_0431 21 COG3786 COG3786, Uncharacterized protein conserved in bacteria Function unknown 120403262 Common - uncharacterized domain 1 Mvan_2271 43 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 120404850 Common - Integrase, catalytic region Mvan_3894 34 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 120402741 Common - transcription factor WhiB Mvan_1741 19 None None None 120406588 Common - hypothetical protein Mvan_5646 6 None None None 120402668 Common - hypothetical protein Mvan_1662 5 COG2068 COG2068, Uncharacterized MobA-related protein General function prediction only 120403692 Common - hypothetical protein Mvan_2708 2 None None None 120404600 Nonpathogen - hypothetical protein Mvan_3632 2 None None None 120405006 Common - amidase Mvan_4052 149 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 120402621 Common - short chain dehydrogenase Mvan_1615 189 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 120404046 Common - malate dehydrogenase Mvan_3067 81 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 120402810 Common - hypothetical protein Mvan_1811 11 None None None 120405857 Common - fumarylacetoacetate (FAA) hydrolase Mvan_4907 163 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 120405273 Common - Rieske (2Fe-2S) domain protein Mvan_4319 80 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 120406865 Common - WD40 domain protein beta Propeller Mvan_5925 3 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 120403266 Common - GCN5-related N-acetyltransferase Mvan_2275 64 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 120406892 Nonpathogen - hypothetical protein Mvan_5957 1 None None None 120406925 Nonpathogen - hypothetical protein Mvan_5992 1 None None None 120402968 Common - alpha/beta hydrolase fold Mvan_1972 73 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 120405497 Common - nitrate reductase, beta subunit Mvan_4545 146 COG1140 NarY, Nitrate reductase beta subunit Energy production and conversion 120402757 Common - PPE family protein Mvan_1757 1 None None None 120403920 Common - Methyltransferase type 12 Mvan_2937 29 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 120406626 Common - transcriptional regulator, TetR family Mvan_5684 12 COG1309 AcrR, Transcriptional regulator Transcription 120405418 Common - transcriptional regulator, TetR family Mvan_4466 42 COG1309 AcrR, Transcriptional regulator Transcription 120402093 Nonpathogen - hypothetical protein Mvan_1078 1 None None None 120404382 Common - LppI Mvan_3409 1 None None None 120402746 Common - S-adenosyl-L-homocysteine hydrolase Mvan_1746 178 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 120404409 Common - peptidase M24 Mvan_3437 248 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 120401471 Common - glycoside hydrolase, family 16 Mvan_0446 28 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 120405375 Common - bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein Mvan_4422 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 120405434 Common - magnesium and cobalt transport protein CorA Mvan_4482 166 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 120402282 Common - PaaX domain protein, C-terminal domain Mvan_1271 16 COG3327 PaaX, Phenylacetic acid-responsive transcriptional repressor Transcription 120404167 Common - hypothetical protein Mvan_3188 1 None None None 120406595 Common - regulatory protein, LuxR Mvan_5653 57 COG3899 COG3899, Predicted ATPase General function prediction only 120406983 Common leuS leucyl-tRNA synthetase Mvan_6054 246 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 120405221 Common - hypothetical protein Mvan_4267 17 None None None 120404429 Common - protein of unknown function DUF355 Mvan_3457 33 COG1839 COG1839, Uncharacterized conserved protein Function unknown 120404349 Common - NAD-dependent epimerase/dehydratase Mvan_3375 90 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 120401893 Common - protein of unknown function DUF58 Mvan_0878 85 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 120406427 Common - cytochrome P450 Mvan_5481 68 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120406087 Common - putative conserved transmembrane protein Mvan_5139 4 None None None 120401147 Common - NAD(P) transhydrogenase, beta subunit Mvan_0119 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 120401130 Common - transcriptional regulator, TetR family Mvan_0102 22 COG1309 AcrR, Transcriptional regulator Transcription 120401766 Common - phosphatidylserine decarboxylase Mvan_0751 90 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 120401698 Common - MMPL domain protein Mvan_0683 36 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 120401606 Common - hypothetical protein Mvan_0590 1 COG5373 COG5373, Predicted membrane protein Function unknown 120405301 Common - threonine synthase Mvan_4347 169 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 120406826 Common - hypothetical protein Mvan_5884 27 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 120404364 Common - binding-protein-dependent transport systems inner membrane component Mvan_3390 194 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 120405952 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Mvan_5003 165 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 120406965 Common - hypothetical protein Mvan_6035 15 COG5650 COG5650, Predicted integral membrane protein Function unknown 120406878 Common - phage integrase family protein Mvan_5939 205 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 120401665 Nonpathogen - hypothetical protein Mvan_0649 4 None None None 120401185 Common - hypothetical protein Mvan_0157 8 None None None 120401621 Common - amino acid permease-associated region Mvan_0605 127 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 120402193 Common - hypothetical protein Mvan_1181 5 COG0398 COG0398, Uncharacterized conserved protein Function unknown 120404403 Common - precorrin-3B C17-methyltransferase Mvan_3431 125 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 120403464 Common - amino acid permease-associated region Mvan_2474 63 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 120401419 Common - acyl-CoA dehydrogenase domain protein Mvan_0394 134 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120404025 Common - Enoyl-CoA hydratase/isomerase Mvan_3046 165 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120403352 Common - hydrogenase expression/formation protein HypD Mvan_2361 109 COG0409 HypD, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 120401299 Common - protein of unknown function DUF222 Mvan_0273 6 COG3000 ERG3, Sterol desaturase Lipid metabolism 120405333 Common - acyl-CoA dehydrogenase domain protein Mvan_4380 134 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120401338 Common - transcriptional regulator, TetR family Mvan_0313 11 COG1309 AcrR, Transcriptional regulator Transcription 120402003 Common - FAD dependent oxidoreductase Mvan_0988 69 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 120404003 Common - thioesterase superfamily protein Mvan_3023 50 COG0824 FcbC, Predicted thioesterase General function prediction only 120403715 Common - hypothetical protein Mvan_2731 13 None None None 120404157 Common - hypothetical protein Mvan_3178 1 None None None 120406450 Common - hypothetical protein Mvan_5507 7 COG3832 COG3832, Uncharacterized conserved protein Function unknown 120404069 Common - inositol-5-monophosphate dehydrogenase Mvan_3090 233 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 120405204 Common - LAO/AO transport system ATPase Mvan_4250 100 COG1703 ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family Amino acid transport and metabolism 120405763 Common - hypothetical protein Mvan_4813 1 None None None 120404585 Common - transcriptional regulator, XRE family Mvan_3617 45 COG1396 HipB, Predicted transcriptional regulators Transcription 120403977 Nonpathogen - hypothetical protein Mvan_2995 2 None None None 120405766 Common - LpqN Mvan_4816 1 None None None 120404047 Common - acetyl-CoA acetyltransferase Mvan_3068 16 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120406054 Nonpathogen - hypothetical protein Mvan_5106 1 None None None 120401029 Common dnaA chromosomal replication initiation protein Mvan_0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 120402887 Common - hydrolase Mvan_1889 31 COG4257 Vgb, Streptogramin lyase Defense mechanisms 120405424 Common - nuclease (RecB family)-like protein Mvan_4472 60 COG2251 COG2251, Predicted nuclease (RecB family) General function prediction only 120406049 Common - Thiosulfate sulfurtransferase Mvan_5101 144 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 120402660 Common - hypothetical protein Mvan_1654 1 None None None 120404557 Common - phage integrase family protein Mvan_3588 128 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 120404062 Common - urease, beta subunit Mvan_3083 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 120402249 Nonpathogen - hypothetical protein Mvan_1237 1 None None None 120405494 Nonpathogen - hypothetical protein Mvan_4542 1 None None None 120403575 Common hisS histidyl-tRNA synthetase Mvan_2590 244 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 120405217 Common - AMP-dependent synthetase and ligase Mvan_4263 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120406951 Common - putative xenobiotic compound monooxygenase, DszA family, A subunit Mvan_6020 71 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120404747 Common - alpha/beta hydrolase fold Mvan_3788 38 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120402803 Common - TrkA-N domain protein Mvan_1804 87 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 120405026 Common - hypothetical protein Mvan_4072 19 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 120401919 Common - aldehyde dehydrogenase Mvan_0904 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 120402389 Common - UspA domain protein Mvan_1378 26 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 120402467 Common - phage tail tape measure protein, TP901 family Mvan_1457 28 COG5283 COG5283, Phage-related tail protein Function unknown 120404037 Common - CMP/dCMP deaminase, zinc-binding Mvan_3058 96 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 120406132 Common - carbon monoxide dehydrogenase subunit G Mvan_5184 34 COG3427 COG3427, Uncharacterized conserved protein Function unknown 120406691 Common - hypothetical protein Mvan_5749 9 None None None 120407000 Common - parB-like partition proteins Mvan_6071 180 COG1475 Spo0J, Predicted transcriptional regulators Transcription 120404937 Common - protein of unknown function DUF140 Mvan_3983 86 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 120401662 Common - hypothetical protein Mvan_0646 13 None None None 120401244 Common - acyl-CoA synthetase Mvan_0218 218 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120406099 Common - cytochrome P450 Mvan_5151 72 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120404100 Common - ABC drug efflux pump, inner membrane subunit, DrrB family Mvan_3121 21 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 120404205 Common - ABC transporter-related protein Mvan_3227 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 120404083 Common - Cyclohexanone monooxygenase Mvan_3104 78 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 120405415 Nonpathogen - hypothetical protein Mvan_4463 1 None None None 120402381 Common - cyclic nucleotide-binding protein Mvan_1370 208 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 120406673 Common - ABC transporter-related protein Mvan_5731 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 120401836 Common - hypothetical protein Mvan_0821 14 None None None 120402501 Common - transcriptional regulator, TetR family Mvan_1492 27 COG1309 AcrR, Transcriptional regulator Transcription 120404826 Nonpathogen - Glycosyltransferase 28, C-terminal domain Mvan_3868 4 COG4671 COG4671, Predicted glycosyl transferase General function prediction only 120404909 Common - Rh family protein/ammonium transporter Mvan_3955 165 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 120406109 Common - cytochrome P450 Mvan_5161 71 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120403255 Common - hypothetical protein Mvan_2264 2 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 120403708 Common - Alcohol dehydrogenase, zinc-binding domain protein Mvan_2724 180 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 120403640 Common - transposase, mutator type Mvan_2656 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 120403558 Nonpathogen - hypothetical protein Mvan_2572 1 None None None 120405291 Common - Sua5/YciO/YrdC/YwlC family protein Mvan_4337 236 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 120402971 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase Mvan_1975 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120401600 Common - Integrase, catalytic region Mvan_0583 146 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 120403694 Common - iron-sulfur cluster binding protein Mvan_2710 94 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 120401751 Common - uncharacterized enzyme Mvan_0736 68 COG2170 COG2170, Uncharacterized conserved protein Function unknown 120402404 Common - Erythromycin esterase Mvan_1393 79 COG2312 COG2312, Erythromycin esterase homolog General function prediction only 120404158 Common - hypothetical protein Mvan_3179 25 COG3687 COG3687, Predicted metal-dependent hydrolase General function prediction only 120404213 Common - putative alkylmercury lyase Mvan_3236 5 None None None 120402512 Common - hypothetical protein Mvan_1503 2 None None None 120406210 Common - Phosphoglycerate mutase Mvan_5262 8 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 120401078 Nonpathogen - hypothetical protein Mvan_0050 1 None None None 120402301 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mvan_1290 212 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 120403350 Common - (NiFe) hydrogenase maturation protein HypF Mvan_2359 111 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 120405620 Common greA transcription elongation factor GreA Mvan_4668 198 COG0782 GreA, Transcription elongation factor Transcription 120406575 Common - beta-lactamase domain protein Mvan_5633 68 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 120406346 Common - putative cold-shock DNA-binding domain protein Mvan_5398 181 COG1278 CspC, Cold shock proteins Transcription 120404550 Common - dihydrolipoamide acetyltransferase Mvan_3579 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 120402433 Common - protein of unknown function DUF21 Mvan_1422 213 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 120405583 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase Mvan_4631 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 120405695 Common - hypothetical protein Mvan_4745 23 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 120406282 Nonpathogen - response regulator receiver and ANTAR domain protein Mvan_5334 1 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 120401400 Common - chromosome replication initiation inhibitor protein Mvan_0375 71 COG0583 LysR, Transcriptional regulator Transcription 120402734 Common - transcription factor WhiB Mvan_1734 19 None None None 120404740 Common - cytochrome P450 Mvan_3781 82 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120406829 Common - hypothetical protein Mvan_5887 6 None None None 120405219 Common - putative adenylate/guanylate cyclase Mvan_4265 87 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 120401916 Common - amidohydrolase 2 Mvan_0901 25 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 120406617 Common - hypothetical protein Mvan_5675 4 None None None 120404524 Common - NLP/P60 protein Mvan_3552 111 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 120401330 Common - Allophanate hydrolase subunit 1 Mvan_0304 105 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 120404582 Common - hypothetical protein Mvan_3614 5 None None None 120405520 Common - O-methyltransferase domain protein Mvan_4568 31 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 120402173 Common - dihydroxy-acid dehydratase Mvan_1161 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 120405748 Common - acyl-CoA synthetase Mvan_4798 215 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120401283 Common - transcriptional regulator, TetR family Mvan_0257 107 COG1309 AcrR, Transcriptional regulator Transcription 120404000 Common - hypothetical protein Mvan_3020 1 None None None 120404030 Common - transcriptional regulator, GntR family Mvan_3051 97 COG1802 GntR, Transcriptional regulators Transcription 120401247 Common - Butyryl-CoA dehydrogenase Mvan_0221 167 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120406204 Common - acyl-CoA dehydrogenase domain protein Mvan_5256 157 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120405376 Common - sulfate adenylyltransferase subunit 2 Mvan_4423 129 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 120404136 Common - 4,5-dihydroxyphthalate decarboxylase Mvan_3157 10 None None None 120401689 Common - peptidase M50 Mvan_0674 39 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 120403915 Common - hypothetical protein Mvan_2932 11 None None None 120404718 Common - FAD dependent oxidoreductase Mvan_3759 148 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 120404028 Common - thioesterase superfamily protein Mvan_3049 12 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 120403258 Common - protein of unknown function DUF1707 Mvan_2267 12 None None None 120404280 Nonpathogen - hypothetical protein Mvan_3305 1 None None None 120403133 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase Mvan_2141 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 120405439 Common - Citrate (pro-3S)-lyase Mvan_4487 118 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 120401838 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase Mvan_0823 200 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 120405368 Common - ring hydroxylating dioxygenase, alpha subunit Mvan_4415 82 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 120404420 Common - 20S proteasome, A and B subunits Mvan_3448 16 COG0638 PRE1, 20S proteasome, alpha and beta subunits Posttranslational modification, protein turnover, chaperones 120406131 Common - Carbon-monoxide dehydrogenase (acceptor) Mvan_5183 108 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 120406421 Common - histidine kinase Mvan_5475 135 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 120402507 Common - Lipocalin family protein Mvan_1498 71 COG3040 Blc, Bacterial lipocalin Cell envelope biogenesis, outer membrane 120404168 Common - Transport protein Mvan_3189 66 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 120402090 Common - FHA domain containing protein Mvan_1075 45 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 120405235 Common - hypothetical protein Mvan_4281 1 None None None 120405784 Common - 5-formyltetrahydrofolate cyclo-ligase Mvan_4834 120 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 120402319 Common rplB 50S ribosomal protein L2 Mvan_1308 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 120404489 Common - protein of unknown function DUF552 Mvan_3517 47 COG1799 COG1799, Uncharacterized protein conserved in bacteria Function unknown 120404238 Common - YfbU family protein Mvan_3262 4 COG3013 COG3013, Uncharacterized conserved protein Function unknown 120406738 Common - intracellular protease, PfpI family Mvan_5796 158 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 120401761 Common - potassium/proton antiporter Mvan_0746 89 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 120401763 Common - protein of unknown function DUF1707 Mvan_0748 8 None None None 120401149 Common - binding-protein-dependent transport systems inner membrane component Mvan_0121 163 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 120401713 Common - luciferase family protein Mvan_0698 50 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120405331 Common - short-chain dehydrogenase/reductase SDR Mvan_4378 75 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 120401850 Common - Xylose isomerase domain protein TIM barrel Mvan_0835 22 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 120404874 Common - dihydrodipicolinate reductase Mvan_3920 20 COG3804 COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase Function unknown 120406655 Common - transcriptional regulator, TetR family Mvan_5713 9 COG1309 AcrR, Transcriptional regulator Transcription 120404832 Common - sulfate ABC transporter, inner membrane subunit CysT Mvan_3874 188 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 120401331 Nonpathogen - hypothetical protein Mvan_0305 1 None None None 120402823 Common - methylmalonate-semialdehyde dehydrogenase Mvan_1824 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 120404207 Common - hypothetical protein Mvan_3229 1 None None None 120401034 Common gyrB DNA gyrase subunit B Mvan_0006 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 120401101 Common - protein of unknown function DUF690 Mvan_0073 8 None None None 120404130 Common - polysaccharide deacetylase Mvan_3151 64 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 120405869 Nonpathogen - hypothetical protein Mvan_4919 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 120405028 Common - glycerol-3-phosphate acyltransferase Mvan_4074 47 COG2937 PlsB, Glycerol-3-phosphate O-acyltransferase Lipid metabolism 120402283 Common - enoyl-CoA hydratase Mvan_1272 179 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120406101 Common - hypothetical protein Mvan_5153 3 None None None 120402739 Common - mannose-6-phosphate isomerase, class I Mvan_1739 42 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 120402750 Common - thymidylate kinase Mvan_1750 25 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 120405886 Common - hypothetical protein Mvan_4936 1 None None None 120405091 Common - hypothetical protein Mvan_4137 17 None None None 120403459 Common - hypothetical protein Mvan_2469 3 None None None 120406370 Common - HAD-superfamily subfamily IB hydrolase, TIGR01490 Mvan_5423 81 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 120405858 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mvan_4908 32 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 120404227 Nonpathogen - hypothetical protein Mvan_3250 1 None None None 120401305 Common - flavin reductase domain protein, FMN-binding Mvan_0279 94 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 120401813 Common - Carboxymuconolactone decarboxylase Mvan_0798 19 COG2128 COG2128, Uncharacterized conserved protein Function unknown 120402892 Common - pyruvate carboxyltransferase Mvan_1894 117 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 120404532 Common - hypothetical protein Mvan_3561 1 None None None 120402184 Common - hypothetical protein Mvan_1172 25 COG4913 COG4913, Uncharacterized protein conserved in bacteria Function unknown 120402335 Common - protein of unknown function DUF336 Mvan_1324 33 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 120403115 Common ilvH acetolactate synthase 3 regulatory subunit Mvan_2123 193 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 120403733 Common - ATPase associated with various cellular activities, AAA_3 Mvan_2749 177 COG0714 COG0714, MoxR-like ATPases General function prediction only 120406092 Common - cytochrome P450 Mvan_5144 67 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120405049 Common - peptidase S9, prolyl oligopeptidase active site domain protein Mvan_4095 131 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 120404947 Common - AMP-dependent synthetase and ligase Mvan_3993 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120404200 Common - arsenical-resistance protein Mvan_3222 132 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 120401083 Common - HD phosphohydrolase-like Mvan_0055 16 COG4341 COG4341, Predicted HD phosphohydrolase General function prediction only 120404979 Common - protein of unknown function DUF81 Mvan_4025 30 COG0730 COG0730, Predicted permeases General function prediction only 120406550 Common - protein of unknown function DUF661 Mvan_5608 6 COG3801 COG3801, Uncharacterized protein conserved in bacteria Function unknown 120405229 Common - amidohydrolase 2 Mvan_4275 18 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 120405624 Common - RDD domain containing protein Mvan_4672 4 None None None 120401453 Common - hypothetical protein Mvan_0428 1 None None None 120404474 Common - Uncharacterized protein UPF0065 Mvan_3502 70 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 120402427 Nonpathogen - hypothetical protein Mvan_1416 1 None None None 120404938 Common - protein of unknown function DUF140 Mvan_3984 148 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 120403141 Common - putative conserved secreted protein Mvan_2149 8 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 120402906 Common - hypothetical protein Mvan_1909 2 None None None 120405599 Common - hypothetical protein Mvan_4647 4 None None None 120403089 Common - glycoside hydrolase, family 57 Mvan_2097 35 COG1543 COG1543, Uncharacterized conserved protein Function unknown 120406587 Common - putative esterase Mvan_5645 22 COG0627 COG0627, Predicted esterase General function prediction only 120406377 Common - Colicin V production protein Mvan_5430 156 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 120405212 Common - L-carnitine dehydratase/bile acid-inducible protein F Mvan_4258 115 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 120401372 Common - 2-nitropropane dioxygenase, NPD Mvan_0347 95 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 120406862 Common - peptidase S9, prolyl oligopeptidase active site domain protein Mvan_5922 145 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 120402954 Nonpathogen - hypothetical protein Mvan_1958 1 None None None 120406640 Common - Glutamate synthase (ferredoxin) Mvan_5698 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 120403063 Common - multi-sensor signal transduction histidine kinase Mvan_2071 102 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 120404031 Common - Amidase Mvan_3052 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 120402661 Common - putative protein UsfY Mvan_1655 1 None None None 120406664 Common - acyl-CoA dehydrogenase domain protein Mvan_5722 151 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120403465 Common - (Uracil-5)-methyltransferase Mvan_2475 176 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 120401189 Common - putative agmatinase Mvan_0161 156 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 120405011 Common - aminopeptidase N Mvan_4057 164 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 120406129 Common - peptidase M15D, vanX D-ala-D-ala dipeptidase Mvan_5181 52 COG2173 DdpX, D-alanyl-D-alanine dipeptidase Cell envelope biogenesis, outer membrane 120404914 Common - monooxygenase, FAD-binding Mvan_3960 88 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 120403546 Common - histidine triad (HIT) protein Mvan_2559 104 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 120405040 Common - Pyruvate dehydrogenase (acetyl-transferring) Mvan_4086 158 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 120401654 Common - Aldose 1-epimerase Mvan_0638 10 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 120402669 Common - hypothetical protein Mvan_1663 4 None None None 120404606 Common - protein of unknown function DUF302 Mvan_3638 43 COG3439 COG3439, Uncharacterized conserved protein Function unknown 120401980 Common - hypothetical protein Mvan_0965 5 COG2976 COG2976, Uncharacterized protein conserved in bacteria Function unknown 120404673 Nonpathogen - hypothetical protein Mvan_3711 1 None None None 120402231 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Mvan_1219 172 COG0388 COG0388, Predicted amidohydrolase General function prediction only 120402277 Common - glycosyl transferase, family 2 Mvan_1266 32 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 120402555 Common - transcriptional regulator, TetR family Mvan_1548 4 COG1309 AcrR, Transcriptional regulator Transcription 120402846 Common - cytochrome P450 Mvan_1848 83 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120406088 Common - protein of unknown function DUF1707 Mvan_5140 10 None None None 120403841 Common - hypothetical protein Mvan_2858 1 None None None 120401216 Common - transcriptional regulator, Fis family Mvan_0189 1 None None None 120403765 Common - hypothetical protein Mvan_2781 5 None None None 120404749 Common - hypothetical protein Mvan_3791 29 COG3540 PhoD, Phosphodiesterase/alkaline phosphatase D Inorganic ion transport and metabolism 120401926 Common - Pyruvate dehydrogenase (acetyl-transferring) Mvan_0911 157 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 120403125 Common gltX glutamyl-tRNA synthetase Mvan_2133 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 120406926 Common - UBA/THIF-type NAD/FAD binding protein Mvan_5993 77 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 120406777 Common - beta-lactamase domain protein Mvan_5835 192 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 120406608 Common - Ferritin, Dps family protein Mvan_5666 88 COG1528 Ftn, Ferritin-like protein Inorganic ion transport and metabolism 120406883 Nonpathogen - hypothetical protein Mvan_5947 1 None None None 120405203 Common - transcriptional regulator, TetR family Mvan_4249 25 COG1309 AcrR, Transcriptional regulator Transcription 120404077 Common - von Willebrand factor, type A Mvan_3098 9 None None None 120405517 Common - hypothetical protein Mvan_4565 5 None None None 120404913 Common - hypothetical protein Mvan_3959 6 None None None 120405592 Common - diguanylate cyclase/phosphodiesterase Mvan_4640 176 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 120405761 Common - putative transcriptional regulator, MerR family Mvan_4811 105 COG0789 SoxR, Predicted transcriptional regulators Transcription 120402880 Common - NADH dehydrogenase subunit D Mvan_1882 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 120402299 Common - amidinotransferase Mvan_1288 38 COG1834 COG1834, N-Dimethylarginine dimethylaminohydrolase Amino acid transport and metabolism 120402091 Common - protein kinase Mvan_1076 157 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 120404405 Common - aminoglycoside phosphotransferase Mvan_3433 21 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 120401828 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Mvan_0813 180 COG0388 COG0388, Predicted amidohydrolase General function prediction only 120401964 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Mvan_0949 55 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 120405428 Common - hypothetical protein Mvan_4476 8 None None None 120404070 Common - ABC transporter-related protein Mvan_3091 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 120402006 Common - geranylgeranyl reductase Mvan_0991 62 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 120405667 Common - protein of unknown function DUF732 Mvan_4716 2 None None None 120401409 Common - transcriptional regulator, TetR family Mvan_0384 24 COG1309 AcrR, Transcriptional regulator Transcription 120404161 Common - NUDIX hydrolase Mvan_3182 20 COG4119 COG4119, Predicted NTP pyrophosphohydrolase DNA replication, recombination, and repair / General function prediction only 120406572 Common - cell wall arabinan synthesis protein Mvan_5630 5 None None None 120403993 Common - hypothetical protein Mvan_3011 1 None None None 120403251 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mvan_2260 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 120406974 Common - protein of unknown function DUF839 Mvan_6044 74 COG3211 PhoX, Predicted phosphatase General function prediction only 120404498 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase Mvan_3526 207 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 120403943 Common - AMP-dependent synthetase and ligase Mvan_2960 204 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120406219 Common - ectoine hydroxylase Mvan_5271 34 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 120403865 Common - acyl-CoA synthetase Mvan_2882 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120406722 Common - protein of unknown function DUF1697 Mvan_5780 37 COG3797 COG3797, Uncharacterized protein conserved in bacteria Function unknown 120401935 Common - protein of unknown function DUF140 Mvan_0920 10 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 120404277 Common - ABC transporter-related protein Mvan_3302 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 120401431 Common - transcriptional regulator, TetR family Mvan_0406 9 COG1309 AcrR, Transcriptional regulator Transcription 120402115 Common - NUDIX hydrolase Mvan_1101 89 COG4111 COG4111, Uncharacterized conserved protein General function prediction only 120406141 Common - NAD-dependent epimerase/dehydratase Mvan_5193 196 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120404151 Common - Carboxylesterase, type B Mvan_3172 76 COG2272 PnbA, Carboxylesterase type B Lipid metabolism 120403103 Common - phosphoribosylglycinamide formyltransferase protein Mvan_2111 8 None None None 120406785 Common - short-chain dehydrogenase/reductase SDR Mvan_5843 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120402262 Common - FabD2 Mvan_1250 1 None None None 120405510 Common - protein of unknown function DUF222 Mvan_4558 5 COG3000 ERG3, Sterol desaturase Lipid metabolism 120401195 Common - hypothetical protein Mvan_0167 5 None None None 120405664 Common - Glutaredoxin-like protein Mvan_4712 26 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 120401528 Common - regulatory protein, ArsR Mvan_0506 84 COG0640 ArsR, Predicted transcriptional regulators Transcription 120405642 Common - Methyltransferase type 11 Mvan_4690 198 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 120406255 Common - alpha/beta hydrolase fold Mvan_5307 166 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120406679 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Mvan_5737 39 COG0748 HugZ, Putative heme iron utilization protein Inorganic ion transport and metabolism 120402522 Common - transcriptional regulator, TetR family Mvan_1513 1 COG1309 AcrR, Transcriptional regulator Transcription 120404821 Common - hypothetical protein Mvan_3863 4 None None None 120406815 Nonpathogen - hypothetical protein Mvan_5873 1 COG3624 PhnG, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 120404101 Common - daunorubicin resistance ABC transporter ATPase subunit Mvan_3122 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 120401171 Common - hypothetical protein Mvan_0143 1 None None None 120404462 Common - hypothetical protein Mvan_3490 8 COG3594 NolL, Fucose 4-O-acetylase and related acetyltransferases Carbohydrate transport and metabolism 120401615 Common - hypothetical protein Mvan_0599 3 COG5470 COG5470, Uncharacterized conserved protein Function unknown 120405841 Common - acetyl-CoA acetyltransferase Mvan_4891 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120404391 Common - Dolichyl-phosphate beta-D-mannosyltransferase Mvan_3418 192 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 120403583 Common - putative helicase Mvan_2598 34 COG3973 COG3973, Superfamily I DNA and RNA helicases General function prediction only 120405317 Common - hypothetical protein Mvan_4363 2 None None None 120404268 Common - hypothetical protein Mvan_3293 18 None None None 120402943 Common - phosphopantetheine-binding protein Mvan_1946 1 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120404369 Common - short-chain dehydrogenase/reductase SDR Mvan_3395 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120405262 Common - hypothetical protein Mvan_4308 38 COG1637 COG1637, Predicted nuclease of the RecB family DNA replication, recombination, and repair 120402647 Common - alkylhydroperoxidase-like protein, AhpD family Mvan_1641 37 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 120402652 Common - two component transcriptional regulator, LuxR family Mvan_1646 216 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 120401235 Nonpathogen - hypothetical protein Mvan_0208 2 None None None 120406946 Nonpathogen - hypothetical protein Mvan_6014 1 None None None 120401564 Common - class II aldolase/adducin family protein Mvan_0543 6 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 120401682 Common - Na+/H+ antiporter NhaA Mvan_0667 132 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 120405279 Common - ATP--cobalamin adenosyltransferase Mvan_4325 129 COG2096 COG2096, Uncharacterized conserved protein Function unknown 120405657 Common - hypothetical protein Mvan_4705 1 None None None 120405725 Common - Dyp-type peroxidase family Mvan_4775 39 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 120401396 Common - cutinase Mvan_0371 3 None None None 120401131 Common - transcriptional regulator, TetR family Mvan_0103 13 COG1309 AcrR, Transcriptional regulator Transcription 120401873 Common - cytochrome P450 Mvan_0858 74 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120403043 Common - Methyltransferase type 11 Mvan_2049 33 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 120404244 Common - phage integrase family protein Mvan_3269 20 None None None 120405053 Common - protein of unknown function DUF853, NPT hydrolase putative Mvan_4099 87 COG0433 COG0433, Predicted ATPase General function prediction only 120406732 Common - zinc finger, CDGSH-type domain protein Mvan_5790 5 COG3369 COG3369, Uncharacterized conserved protein Function unknown 120402635 Common - hypothetical protein Mvan_1629 2 None None None 120401733 Common - amino acid permease-associated region Mvan_0718 17 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 120403273 Common - regulatory protein GntR, HTH Mvan_2282 131 COG2186 FadR, Transcriptional regulators Transcription 120401890 Common - hypothetical protein Mvan_0875 3 None None None 120404013 Common - glycosyl transferase, group 1 Mvan_3033 183 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 120401429 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Mvan_0404 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 120402218 Nonpathogen - hypothetical protein Mvan_1206 1 None None None 120403239 Common - luciferase family protein Mvan_2248 100 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120403484 Common - methylated-DNA--protein-cysteine methyltransferase Mvan_2495 213 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 120406069 Common - putative aminopeptidase 2 Mvan_5121 44 COG1362 LAP4, Aspartyl aminopeptidase Amino acid transport and metabolism 120401245 Common - Enoyl-CoA hydratase/isomerase Mvan_0219 156 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120402960 Common - acyl-CoA dehydrogenase domain protein Mvan_1964 134 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120403499 Nonpathogen - hypothetical protein Mvan_2511 1 None None None 120404123 Nonpathogen - hypothetical protein Mvan_3144 1 COG1549 COG1549, Queuine tRNA-ribosyltransferases, contain PUA domain Translation, ribosomal structure and biogenesis 120405014 Common - hypothetical protein Mvan_4060 1 None None None 120406941 Nonpathogen - hypothetical protein Mvan_6009 1 None None None 120404245 Common - deoxyribodipyrimidine photolyase-related protein Mvan_3270 59 COG3046 COG3046, Uncharacterized protein related to deoxyribodipyrimidine photolyase General function prediction only 120403283 Common - hypothetical protein Mvan_2292 4 None None None 120405055 Common - protein of unknown function DUF1486 Mvan_4101 13 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 120405827 Common pgi glucose-6-phosphate isomerase Mvan_4877 198 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 120401552 Common - hypothetical protein Mvan_0531 7 COG3777 COG3777, Uncharacterized conserved protein Function unknown 120403287 Common - two component transcriptional regulator, winged helix family Mvan_2296 226 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 120405881 Common - hypothetical protein Mvan_4931 1 None None None 120405296 Common - transcriptional regulator, TetR family Mvan_4342 50 COG1309 AcrR, Transcriptional regulator Transcription 120405149 Common - hypothetical protein Mvan_4195 2 None None None 120406012 Common - AMP-dependent synthetase and ligase Mvan_5064 214 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120401664 Common - nitrile hydratase, alpha subunit Mvan_0648 21 None None None 120401163 Common - virulence factor Mce family protein Mvan_0135 16 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120406562 Common - ABC-2 type transporter Mvan_5620 75 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 120401634 Common - aminotransferase AlaT Mvan_0618 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 120403328 Common - transcriptional regulator, TetR family Mvan_2337 32 COG1309 AcrR, Transcriptional regulator Transcription 120401513 Common - hypothetical protein Mvan_0491 34 None None None 120404633 Common - Heavy metal transport/detoxification protein Mvan_3669 19 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 120406301 Common - beta-lactamase Mvan_5353 15 COG2367 PenP, Beta-lactamase class A Defense mechanisms 120404700 Common - Integrase, catalytic region Mvan_3741 141 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 120403167 Common - chromosome segregation protein SMC Mvan_2175 181 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 120402247 Common rplK 50S ribosomal protein L11 Mvan_1235 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 120404694 Nonpathogen - hypothetical protein Mvan_3735 1 None None None 120405142 Common - amidohydrolase Mvan_4188 82 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 120404373 Common - Enoyl-CoA hydratase/isomerase Mvan_3400 174 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120403683 Common - protein of unknown function UPF0052 and CofD Mvan_2699 90 COG0391 COG0391, Uncharacterized conserved protein Function unknown 120401672 Nonpathogen - hypothetical protein Mvan_0657 1 None None None 120403623 Common - putative transglycosylase associated protein Mvan_2638 3 None None None 120401744 Nonpathogen - hypothetical protein Mvan_0729 1 None None None 120401940 Common - virulence factor Mce family protein Mvan_0925 19 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120403397 Common - hydrogenase assembly chaperone hypC/hupF Mvan_2406 90 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 120403907 Nonpathogen - hypothetical protein Mvan_2924 1 None None None 120402147 Common - hypothetical protein Mvan_1134 20 COG4924 COG4924, Uncharacterized protein conserved in bacteria Function unknown 120406155 Common - acyl-CoA dehydrogenase domain protein Mvan_5207 125 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120404656 Common - cytochrome c biogenesis protein, transmembrane region Mvan_3693 84 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 120403834 Common - protein of unknown function DUF140 Mvan_2850 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 120405103 Common - virulence factor Mce family protein Mvan_4149 23 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120403873 Common - hypothetical protein Mvan_2890 55 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 120405244 Common - Rhomboid family protein Mvan_4290 30 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 120401474 Common - hypothetical protein Mvan_0449 16 None None None 120404071 Common - binding-protein-dependent transport systems inner membrane component Mvan_3092 111 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 120403343 Common - Beta-lactamase Mvan_2352 68 COG2367 PenP, Beta-lactamase class A Defense mechanisms 120406705 Nonpathogen - hypothetical protein Mvan_5763 1 None None None 120402224 Common - short-chain dehydrogenase/reductase SDR Mvan_1212 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120403750 Common - hypothetical protein Mvan_2766 1 None None None 120401091 Nonpathogen - hypothetical protein Mvan_0063 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 120405025 Common - transposase, IS4 family protein Mvan_4071 26 None None None 120402129 Common - hypothetical protein Mvan_1115 3 None None None 120406366 Common - phage integrase family protein Mvan_5419 9 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 120405627 Common - Alpha/beta hydrolase fold-3 domain protein Mvan_4675 113 COG0657 Aes, Esterase/lipase Lipid metabolism 120404212 Nonpathogen - hypothetical protein Mvan_3234 1 COG3462 COG3462, Predicted membrane protein Function unknown 120405575 Common - short-chain dehydrogenase/reductase SDR Mvan_4623 235 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 120405754 Common - glutamate dehydrogenase Mvan_4804 172 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 120403403 Common - hypothetical protein Mvan_2412 7 None None None 120404957 Common - Oxidoreductase FAD-binding domain protein Mvan_4003 130 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 120406688 Common - hypothetical protein Mvan_5746 1 None None None 120404145 Common - hypothetical protein Mvan_3166 7 None None None 120402211 Nonpathogen - hypothetical protein Mvan_1199 1 None None None 120404107 Common - beta-ketoacyl synthase Mvan_3128 210 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 120401353 Common - transcriptional regulator, LysR family Mvan_0328 185 COG0583 LysR, Transcriptional regulator Transcription 120406909 Nonpathogen - hypothetical protein Mvan_5976 1 None None None 120402053 Common - cytochrome P450 Mvan_1038 91 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120402967 Common - Dimethylaniline monooxygenase (N-oxide-forming) Mvan_1971 80 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 120403966 Common - catalase/peroxidase HPI Mvan_2984 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 120404968 Common - drug resistance transporter, EmrB/QacA subfamily Mvan_4014 224 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120403857 Common - hypothetical protein Mvan_2874 2 None None None 120406029 Common - putative conserved exported protein Mvan_5081 4 None None None 120405874 Common - hypothetical protein Mvan_4924 1 None None None 120401685 Common - fructose-bisphosphate aldolase Mvan_0670 115 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 120402046 Common - aldehyde dehydrogenase Mvan_1031 136 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 120401164 Common - virulence factor Mce family protein Mvan_0136 10 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120402077 Common - transcriptional regulator, XRE family Mvan_1062 41 COG1396 HipB, Predicted transcriptional regulators Transcription 120405700 Common - Hemerythrin HHE cation binding domain protein Mvan_4750 11 None None None 120406038 Common - phosphate ABC transporter, inner membrane subunit PstA Mvan_5090 227 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 120404287 Common - acetylglutamate kinase Mvan_3312 201 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 120402659 Common - restriction endonuclease Mvan_1653 9 COG1787 COG1787, Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes Defense mechanisms 120403216 Common - hypothetical protein Mvan_2225 13 None None None 120406981 Common - short chain dehydrogenase Mvan_6051 234 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 120405419 Common - sulfatase Mvan_4467 71 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 120404095 Common - hypothetical protein Mvan_3116 6 None None None 120405539 Common - acyl-CoA dehydrogenase domain protein Mvan_4587 158 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120401075 Common - polysaccharide deacetylase Mvan_0047 112 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 120402873 Common - NADH dehydrogenase subunit K Mvan_1875 164 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 120404190 Common - isocitrate dehydrogenase, NADP-dependent Mvan_3212 65 COG2838 Icd, Monomeric isocitrate dehydrogenase Energy production and conversion 120404815 Common - Ferredoxin--nitrite reductase Mvan_3857 161 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 120403810 Common - hypothetical protein Mvan_2826 2 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 120401999 Nonpathogen - hypothetical protein Mvan_0984 1 None None None 120403853 Common - hypothetical protein Mvan_2870 3 None None None 120402596 Common - cytidine deaminase Mvan_1590 108 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 120403893 Common - hypothetical protein Mvan_2910 1 None None None 120403899 Common - Orn/Lys/Arg decarboxylase, major region Mvan_2916 89 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 120405249 Common - hypothetical protein Mvan_4295 13 None None None 120401804 Common - acetoin reductases Mvan_0789 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120405530 Common - L-carnitine dehydratase/bile acid-inducible protein F Mvan_4578 115 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 120403682 Common - hypothetical protein Mvan_2698 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 120402762 Common - conserved hypothetical alanine arginine proline rich protein Mvan_1763 3 None None None 120404118 Common - protein of unknown function DUF881 Mvan_3139 24 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 120403757 Common lspA lipoprotein signal peptidase Mvan_2773 30 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 120402387 Common - hypothetical protein Mvan_1376 5 None None None 120406960 Common - DnaB domain protein helicase, C-terminal domain protein Mvan_6030 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 120402903 Common - acyl-CoA dehydrogenase domain protein Mvan_1906 147 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120401105 Common - PPE protein Mvan_0077 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 120402415 Common - hypothetical protein Mvan_1404 8 COG1503 eRF1, Peptide chain release factor 1 (eRF1) Translation, ribosomal structure and biogenesis 120405954 Common - ABC transporter-related protein Mvan_5005 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 120405258 Common - hypothetical protein Mvan_4304 7 None None None 120402163 Common - hypothetical protein Mvan_1151 1 None None None 120403553 Common - SNO glutamine amidotransferase Mvan_2566 85 COG0311 PDX2, Predicted glutamine amidotransferase involved in pyridoxine biosynthesis Coenzyme metabolism 120404041 Common - AAA ATPase, central domain protein Mvan_3062 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 120402070 Common - fatty acid desaturase Mvan_1055 32 COG3239 DesA, Fatty acid desaturase Lipid metabolism 120405185 Common - peptidase M24 Mvan_4231 58 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 120402703 Nonpathogen - Methyltransferase type 12 Mvan_1700 1 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 120403665 Nonpathogen - hypothetical protein Mvan_2681 4 None None None 120404886 Common - VWA containing CoxE family protein Mvan_3932 44 COG3552 CoxE, Protein containing von Willebrand factor type A (vWA) domain General function prediction only 120404920 Common - regulatory protein, LacI Mvan_3966 37 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 120405475 Common - NUDIX hydrolase Mvan_4523 116 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 120405174 Common - transcriptional regulator, TetR family Mvan_4220 9 COG1309 AcrR, Transcriptional regulator Transcription 120406854 Common - putative outer membrane adhesin like proteiin Mvan_5913 53 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 120402591 Common - putative transposase, IS891/IS1136/IS1341 family Mvan_1584 67 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 120405334 Nonpathogen - hypothetical protein Mvan_4381 1 None None None 120403514 Nonpathogen - hypothetical protein Mvan_2526 1 None None None 120402485 Common - acyl-CoA dehydrogenase domain protein Mvan_1476 164 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120403387 Common - CinA domain protein Mvan_2396 167 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 120401610 Common - transcriptional regulator, TetR family Mvan_0594 99 COG1309 AcrR, Transcriptional regulator Transcription 120406728 Nonpathogen - hypothetical protein Mvan_5786 1 None None None 120406090 Nonpathogen - hypothetical protein Mvan_5142 3 None None None 120402956 Common - hypothetical protein Mvan_1960 21 None None None 120405793 Common - integral membrane sensor signal transduction histidine kinase Mvan_4843 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 120405113 Common - hypothetical protein Mvan_4159 25 COG1141 Fer, Ferredoxin Energy production and conversion 120405287 Common - F0F1 ATP synthase subunit C Mvan_4333 2 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 120403024 Common - hypothetical protein Mvan_2030 8 None None None 120405577 Common - translation-associated GTPase Mvan_4625 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 120404308 Common - hypothetical protein Mvan_3334 3 None None None 120406157 Common - acyl-CoA synthetase Mvan_5209 210 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120403079 Common - ABC transporter-related protein Mvan_2087 249 COG1119 ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA Inorganic ion transport and metabolism 120404668 Common - transcriptional repressor, CopY family Mvan_3706 31 COG3682 COG3682, Predicted transcriptional regulator Transcription 120404713 Common - (acyl-carrier protein) S-malonyltransferase Mvan_3754 208 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 120403304 Common - protein of unknown function DUF448 Mvan_2313 35 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 120404627 Common - hypothetical protein Mvan_3663 36 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 120404322 Nonpathogen - hypothetical protein Mvan_3348 1 None None None 120401209 Common - protein of unknown function DUF58 Mvan_0181 61 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 120402197 Common - short-chain dehydrogenase/reductase SDR Mvan_1185 195 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120401581 Common - fumarate lyase Mvan_0562 190 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 120401588 Common - hypothetical protein Mvan_0570 2 None None None 120402965 Common - hypothetical protein Mvan_1969 3 None None None 120403650 Common - MihF Mvan_2666 16 None None None 120406444 Common - hypothetical protein Mvan_5500 13 None None None 120405192 Common - alpha/beta hydrolase fold Mvan_4238 127 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120403307 Common - phosphoesterase, RecJ domain protein Mvan_2316 73 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 120402991 Common - amidohydrolase 2 Mvan_1996 30 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 120403410 Common - recA protein Mvan_2420 215 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 120401642 Common - conserved hypothetical proline rich protein Mvan_0626 5 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 120406001 Common moaC molybdenum cofactor biosynthesis protein C Mvan_5052 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 120405631 Common - protein of unknown function DUF1112 Mvan_4679 28 COG4760 COG4760, Predicted membrane protein Function unknown 120403565 Common - aldehyde dehydrogenase Mvan_2580 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 120404950 Common - helix-turn-helix- domain containing protein, AraC type Mvan_3996 147 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 120403512 Nonpathogen - hypothetical protein Mvan_2524 1 None None None 120402226 Common - regulatory protein, LuxR Mvan_1214 41 COG3899 COG3899, Predicted ATPase General function prediction only 120406528 Common - 2-nitropropane dioxygenase, NPD Mvan_5586 125 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 120405558 Common - protein of unknown function DUF140 Mvan_4606 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 120406976 Common - regulatory protein GntR, HTH Mvan_6046 71 COG1802 GntR, Transcriptional regulators Transcription 120403196 Common - Siderophore-interacting protein Mvan_2205 63 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 120402026 Common - PE-PPE, C-terminal domain protein Mvan_1011 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 120403953 Common tpx thiol peroxidase Mvan_2971 87 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 120403967 Common - lipolytic enzyme, G-D-S-L family Mvan_2985 3 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 120405082 Common - low temperature requirement A Mvan_4128 24 COG4292 COG4292, Predicted membrane protein Function unknown 120405407 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mvan_4455 38 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 120403780 Common - Triacylglycerol lipase Mvan_2796 19 COG2267 PldB, Lysophospholipase Lipid metabolism 120406252 Nonpathogen - hypothetical protein Mvan_5304 4 None None None 120401697 Common - cytochrome P450 Mvan_0682 79 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120403424 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase Mvan_2434 205 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 120405039 Common - Transketolase, central region Mvan_4085 212 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 120402519 Common - hypothetical protein Mvan_1510 7 None None None 120405876 Common - protein of unknown function DUF1365 Mvan_4926 60 COG3496 COG3496, Uncharacterized conserved protein Function unknown 120405893 Common - GCN5-related N-acetyltransferase Mvan_4944 89 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 120405973 Common - pyridoxamine 5'-phosphate oxidase Mvan_5024 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 120406473 Common - hypothetical protein Mvan_5530 6 None None None 120401345 Common - hypothetical protein Mvan_0320 1 None None None 120404895 Common - heat shock protein Hsp20 Mvan_3941 131 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 120404800 Common - MbtH domain protein Mvan_3842 37 COG3251 COG3251, Uncharacterized protein conserved in bacteria Function unknown 120401264 Common - acyl-CoA dehydrogenase domain protein Mvan_0238 144 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120404315 Common - fructose-1,6-bisphosphate aldolase Mvan_3341 35 COG3588 COG3588, Fructose-1,6-bisphosphate aldolase Carbohydrate transport and metabolism 120403214 Common - radical SAM enzyme, Cfr family Mvan_2223 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 120403975 Common - hypothetical protein Mvan_2993 1 None None None 120404467 Common - Rieske (2Fe-2S) domain protein Mvan_3495 82 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 120406031 Common - hypothetical protein Mvan_5083 21 COG3662 COG3662, Uncharacterized protein conserved in bacteria Function unknown 120405417 Common - cytochrome P450 Mvan_4465 66 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120406225 Common - Transthyretin Mvan_5277 63 COG2351 COG2351, Transthyretin-like protein General function prediction only 120404847 Nonpathogen - hypothetical protein Mvan_3891 1 None None None 120405461 Common - dihydropteroate synthase Mvan_4509 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 120403577 Common - ABC transporter-related protein Mvan_2592 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 120404824 Nonpathogen - hypothetical protein Mvan_3866 1 None None None 120402832 Common - integral membrane sensor signal transduction histidine kinase Mvan_1833 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 120406877 Common - phage integrase family protein Mvan_5938 153 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 120406763 Common - hypothetical protein Mvan_5821 1 COG4547 CobT, Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase) Coenzyme metabolism 120401776 Common - PE-PPE, C-terminal domain protein Mvan_0761 1 None None None 120402540 Common - nitroreductase Mvan_1532 27 COG0778 NfnB, Nitroreductase Energy production and conversion 120402787 Common - Phosphoglycerate mutase Mvan_1788 121 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 120403823 Common - putative adenylate/guanylate cyclase Mvan_2839 38 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 120401043 Common - acyl-CoA synthetase Mvan_0015 220 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120401678 Common - tRNA/rRNA methyltransferase (SpoU) Mvan_0663 70 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 120404256 Common xerD site-specific tyrosine recombinase XerD Mvan_3281 220 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 120406824 Common - alpha/beta hydrolase fold Mvan_5882 130 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120403364 Common - protein of unknown function DUF222 Mvan_2373 5 COG3000 ERG3, Sterol desaturase Lipid metabolism 120403790 Common hisB imidazoleglycerol-phosphate dehydratase Mvan_2806 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 120406906 Common - transposase IS3/IS911 family protein Mvan_5972 39 None None None 120401080 Nonpathogen - hypothetical protein Mvan_0052 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 120401523 Common - virulence factor Mce family protein Mvan_0501 43 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120401180 Common - hypothetical protein Mvan_0152 6 None None None 120401902 Common - hypothetical protein Mvan_0887 27 COG3222 COG3222, Uncharacterized protein conserved in bacteria Function unknown 120401945 Common - helix-turn-helix domain protein Mvan_0930 41 None None None 120403317 Common - hypothetical protein Mvan_2326 1 None None None 120404178 Nonpathogen - PE-PGRS family protein Mvan_3199 1 None None None 120406111 Common - hypothetical protein Mvan_5163 6 None None None 120401666 Common - hypothetical protein Mvan_0650 8 None None None 120405790 Common - hypothetical protein Mvan_4840 2 None None None 120401924 Common - ferredoxin Mvan_0909 22 COG0633 Fdx, Ferredoxin Energy production and conversion 120401125 Common - phosphoenolpyruvate-protein phosphotransferase Mvan_0097 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 120405800 Common - acyl-CoA dehydrogenase domain protein Mvan_4850 158 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120404641 Common - protein of unknown function DUF302 Mvan_3677 44 COG3439 COG3439, Uncharacterized conserved protein Function unknown 120401228 Common - phosphoenolpyruvate carboxykinase Mvan_0201 59 COG1274 PckA, Phosphoenolpyruvate carboxykinase (GTP) Energy production and conversion 120403879 Common - short-chain dehydrogenase/reductase SDR Mvan_2896 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120401954 Common - phosphate transporter Mvan_0939 160 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 120406320 Common - ATP-dependent metalloprotease FtsH Mvan_5372 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 120402142 Common - hypothetical protein Mvan_1129 1 None None None 120404838 Common - hypothetical protein Mvan_3880 1 None None None 120403047 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mvan_2053 20 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 120403310 Common - Methyltransferase type 11 Mvan_2319 155 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 120401546 Common - ring hydroxylating dioxygenase, alpha subunit Mvan_0525 80 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 120406415 Nonpathogen - hypothetical protein Mvan_5468 1 None None None 120401161 Common - protein of unknown function DUF140 Mvan_0133 71 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 120403473 Common - Chlorite dismutase Mvan_2483 33 COG3253 COG3253, Uncharacterized conserved protein Function unknown 120406411 Common - peptide chain release factor 3 Mvan_5464 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 120406990 Common - metal dependent phosphohydrolase Mvan_6061 214 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 120406272 Common - periplasmic solute binding protein Mvan_5324 166 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 120405903 Common - thiamine pyrophosphate enzyme domain protein TPP-binding Mvan_4954 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 120404125 Common - aminotransferase class-III Mvan_3146 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 120402748 Nonpathogen - hypothetical protein Mvan_1748 1 None None None 120403319 Common - 4'-phosphopantetheinyl transferase Mvan_2328 32 COG2977 EntD, Phosphopantetheinyl transferase component of siderophore synthetase Secondary metabolites biosynthesis, transport, and catabolism 120403643 Common - pyrimidine regulatory protein PyrR Mvan_2659 109 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 120402549 Common - 6,7-dihydropteridine reductase Mvan_1541 113 COG1017 Hmp, Hemoglobin-like flavoprotein Energy production and conversion 120404570 Common - protein of unknown function UPF0089 Mvan_3601 28 None None None 120405412 Common - putative conserved lipoprotein LppH Mvan_4460 1 None None None 120404138 Common - amidohydrolase Mvan_3159 164 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 120406802 Common - transcriptional regulator, TetR family Mvan_5860 63 COG1309 AcrR, Transcriptional regulator Transcription 120405915 Common - AMP-dependent synthetase and ligase Mvan_4966 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120403704 Common - transketolase Mvan_2720 221 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 120401596 Common - transposase, IS4 family protein Mvan_0579 25 COG5421 COG5421, Transposase DNA replication, recombination, and repair 120404501 Common - Peptidoglycan glycosyltransferase Mvan_3529 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 120405809 Common - hypothetical protein Mvan_4859 1 None None None 120405689 Common - putative conserved lipoprotein LppH Mvan_4738 1 None None None 120406534 Nonpathogen - hypothetical protein Mvan_5592 1 None None None 120401749 Common - putative tuberculin related peptide Mvan_0734 1 None None None 120406539 Common - protein of unknown function DUF1089 Mvan_5597 7 COG3554 COG3554, Uncharacterized protein conserved in bacteria Function unknown 120402349 Common rplR 50S ribosomal protein L18 Mvan_1338 215 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 120404184 Common - CheB methylesterase Mvan_3206 132 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 120403336 Common - short chain dehydrogenase Mvan_2345 236 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 120405993 Common - hypothetical protein Mvan_5044 9 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 120406696 Nonpathogen - Glyoxalase/bleomycin resistance protein/dioxygenase Mvan_5754 2 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 120403447 Common - Endoribonuclease L-PSP Mvan_2457 109 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 120404300 Common rplT 50S ribosomal protein L20 Mvan_3326 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 120401066 Common - Excinuclease ABC, C subunit domain protein Mvan_0038 9 None None None 120403068 Common - (2Fe-2S)-binding domain protein Mvan_2076 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 120406837 Common - beta-lactamase Mvan_5895 149 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 120406546 Common - Phosphoglycerate mutase Mvan_5604 53 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 120405839 Common - 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase Mvan_4889 92 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 120405988 Common - hypothetical protein Mvan_5039 18 None None None 120406503 Common - hypothetical protein Mvan_5561 12 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 120401336 Common - Lysine exporter protein (LYSE/YGGA) Mvan_0310 81 COG1279 COG1279, Lysine efflux permease General function prediction only 120404987 Common - formate dehydrogenase accessory protein Mvan_4033 137 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 120401649 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Mvan_0633 11 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 120406036 Common - phosphate uptake regulator, PhoU Mvan_5088 190 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 120406468 Common - cytochrome P450 Mvan_5525 74 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120401957 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mvan_0942 8 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 120405941 Common - enoyl-CoA hydratase Mvan_4992 177 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120405605 Common - fatty acid desaturase, type 2 Mvan_4653 8 None None None 120402250 Common - PE-PPE, C-terminal domain protein Mvan_1238 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 120402777 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Mvan_1778 172 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 120404180 Common - Catalase Mvan_3201 125 COG0753 KatE, Catalase Inorganic ion transport and metabolism 120405034 Common - dienelactone hydrolase Mvan_4080 72 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 120405478 Common - delta-1-pyrroline-5-carboxylate dehydrogenase Mvan_4526 217 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 120406022 Common - hypothetical protein Mvan_5074 23 COG5207 UBP14, Isopeptidase T Posttranslational modification, protein turnover, chaperones 120402864 Common - amine oxidase Mvan_1866 28 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 120403939 Common - Methyltransferase type 12 Mvan_2956 20 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 120406014 Common - 3-hydroxyacyl-CoA dehydrogenase, NAD-binding Mvan_5066 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 120406153 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase Mvan_5205 233 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120402915 Common - diguanylate cyclase/phosphodiesterase Mvan_1918 174 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 120405220 Common - General substrate transporter Mvan_4266 120 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 120404132 Common - Amidase Mvan_3153 39 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 120406376 Common - alpha/beta hydrolase fold Mvan_5429 130 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120401437 Common - protein of unknown function DUF690 Mvan_0412 7 None None None 120406513 Common - hypothetical protein Mvan_5571 18 None None None 120406070 Common - Dyp-type peroxidase family Mvan_5122 54 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 120401270 Common - response regulator receiver protein Mvan_0244 19 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 120401690 Common - cytochrome P450 Mvan_0675 88 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120402624 Common - hypothetical protein Mvan_1618 21 None None None 120405179 Common - acyl-CoA synthetase Mvan_4225 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120404561 Nonpathogen - hypothetical protein Mvan_3592 1 None None None 120401275 Common - hypothetical protein Mvan_0249 7 None None None 120402292 Common - elongation factor G Mvan_1281 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 120403108 Common - 6-phosphofructokinase Mvan_2116 161 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 120401789 Common - putative antibiotic-transport integral membrane leucine and alanine and valine rich protein ABC transporter Mvan_0774 9 None None None 120402539 Common - Integrase, catalytic region Mvan_1531 63 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 120405965 Common - hypothetical protein Mvan_5016 2 None None None 120406559 Common - hypothetical protein Mvan_5617 12 None None None 120404632 Common - protein of unknown function DUF156 Mvan_3668 94 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 120406790 Common - putative transcriptional regulator Mvan_5848 15 COG2345 COG2345, Predicted transcriptional regulator Transcription 120404396 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Mvan_3423 12 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 120405770 Common - hypothetical protein Mvan_4820 10 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 120402358 Common secY preprotein translocase subunit SecY Mvan_1347 224 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 120402560 Common metX homoserine O-acetyltransferase Mvan_1553 131 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 120405303 Common - diaminopimelate decarboxylase Mvan_4349 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 120404452 Common - phosphatidylinositol 3- and 4-kinase, catalytic Mvan_3480 18 None None None 120402050 Common - hypothetical protein Mvan_1035 14 None None None 120402970 Common - acyl-CoA dehydrogenase domain protein Mvan_1974 161 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120406756 Common - acyl-CoA thioesterase Mvan_5814 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 120404422 Common - protein of unknown function DUF797 Mvan_3450 4 None None None 120402285 Common - hypothetical protein Mvan_1274 2 None None None 120402207 Common - Isoprenylcysteine carboxyl methyltransferase Mvan_1195 15 COG1755 COG1755, Uncharacterized protein conserved in bacteria Function unknown 120403018 Common - carbon starvation protein CstA Mvan_2024 108 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 120405898 Common - Cyclopropane-fatty-acyl-phospholipid synthase Mvan_4949 128 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 120405830 Common - cytochrome P450 Mvan_4880 70 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120405484 Common - fumarylacetoacetate (FAA) hydrolase Mvan_4532 156 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 120402398 Common - UspA domain protein Mvan_1387 14 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 120402429 Common - hypothetical protein Mvan_1418 7 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 120405384 Common - binding-protein-dependent transport systems inner membrane component Mvan_4431 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 120405733 Common - ribose-phosphate pyrophosphokinase Mvan_4783 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 120406471 Common - hypothetical protein Mvan_5528 84 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 120402083 Common - glycosyl transferase, family 51 Mvan_1068 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 120403695 Common - protein of unknown function DUF162 Mvan_2711 49 COG1556 COG1556, Uncharacterized conserved protein Function unknown 120401879 Common - glutamate-1-semialdehyde aminotransferase Mvan_0864 236 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 120403662 Nonpathogen - hypothetical protein Mvan_2678 2 None None None 120404598 Common - helix-turn-helix domain protein Mvan_3630 2 None None None 120402037 Common - binding-protein-dependent transport systems inner membrane component Mvan_1022 218 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 120402368 Common - GAF sensor signal transduction histidine kinase Mvan_1357 145 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 120403450 Common - O-methyltransferase, family 2 Mvan_2460 44 None None None 120403278 Common - Methyltransferase type 11 Mvan_2287 89 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 120406453 Common - glutamine amidotransferase, class-II Mvan_5510 232 COG0067 GltB, Glutamate synthase domain 1 Amino acid transport and metabolism 120401491 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mvan_0467 208 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 120402996 Common - cytochrome P450 Mvan_2001 73 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120402062 Common - hypothetical protein Mvan_1047 1 None None None 120401975 Common - virulence factor Mce family protein Mvan_0960 39 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120405843 Common - 3-oxoacid CoA-transferase, A subunit Mvan_4893 103 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 120404754 Common - anti-sigma-factor antagonist Mvan_3796 1 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 120402856 Common - 4-aminobutyrate aminotransferase Mvan_1858 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 120405588 Common - hypothetical protein Mvan_4636 22 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120404879 Common - iojap-like protein Mvan_3925 187 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 120403153 Common - 2,5-didehydrogluconate reductase Mvan_2161 183 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 120405746 Common - daunorubicin resistance ABC transporter ATPase subunit Mvan_4796 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 120405569 Common - hypothetical protein Mvan_4617 1 None None None 120404345 Common - periplasmic solute binding protein Mvan_3371 150 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 120403622 Common - Activator of Hsp90 ATPase 1 family protein Mvan_2637 20 COG3832 COG3832, Uncharacterized conserved protein Function unknown 120405199 Common - monooxygenase, FAD-binding Mvan_4245 102 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 120404508 Common - Polyprenyl synthetase Mvan_3536 242 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 120406834 Common - oxidoreductase, molybdopterin binding Mvan_5892 124 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 120402674 Common - Fe-S metabolism associated SufE Mvan_1668 21 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 120402471 Nonpathogen - hypothetical protein Mvan_1461 1 None None None 120404438 Common - ribonucleotide-diphosphate reductase subunit beta Mvan_3466 17 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 120402530 Common - short-chain dehydrogenase/reductase SDR Mvan_1521 175 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 120403001 Common - cytochrome P450 Mvan_2007 84 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120402059 Common - alanine dehydrogenase/PNT domain protein Mvan_1044 106 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 120405614 Common - undecaprenyl diphosphate synthase Mvan_4662 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 120406216 Common - putative CoA transferase beta subunit Mvan_5268 34 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 120402160 Nonpathogen - hypothetical protein Mvan_1148 1 None None None 120402450 Common - cutinase Mvan_1439 3 None None None 120402618 Common - amidohydrolase Mvan_1612 166 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 120401233 Common - hypothetical protein Mvan_0206 13 None None None 120401500 Common - phage integrase family protein Mvan_0478 30 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 120404922 Common - Inositol 2-dehydrogenase Mvan_3968 171 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 120402553 Common - ABC transporter-related protein Mvan_1546 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 120406449 Common - regulatory protein, ArsR Mvan_5506 95 COG0640 ArsR, Predicted transcriptional regulators Transcription 120405007 Common - ribose-5-phosphate isomerase B Mvan_4053 127 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 120406336 Common - putative conserved integral membrane protein Mvan_5388 3 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 120403224 Common - transcriptional regulator, TetR family Mvan_2233 33 COG1309 AcrR, Transcriptional regulator Transcription 120402761 Common - preprotein translocase subunit SecA Mvan_1762 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 120402598 Common - adenosine deaminase Mvan_1592 102 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 120402563 Common - exodeoxyribonuclease III Xth Mvan_1556 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 120405426 Common - drug resistance transporter, EmrB/QacA subfamily Mvan_4474 226 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120406275 Common - hypothetical protein Mvan_5327 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 120401285 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase Mvan_0259 234 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120405125 Common - protein of unknown function DUF35 Mvan_4171 86 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120403433 Common - hypothetical protein Mvan_2443 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 120406399 Common - putative conserved transmembrane protein Mvan_5452 9 None None None 120402041 Common - Alkaline phosphatase Mvan_1026 60 COG3540 PhoD, Phosphodiesterase/alkaline phosphatase D Inorganic ion transport and metabolism 120402693 Common - Integrase, catalytic region Mvan_1688 49 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 120406356 Nonpathogen - hypothetical protein Mvan_5409 1 None None None 120402149 Common - transcriptional regulator, XRE family Mvan_1136 2 COG1396 HipB, Predicted transcriptional regulators Transcription 120403799 Common - trp region conserved hypothetical membrane protein Mvan_2815 1 None None None 120405353 Common - protein of unknown function DUF140 Mvan_4400 34 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 120401203 Common - protein of unknown function DUF156 Mvan_0175 94 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 120404484 Common - domain of unknown function DUF1731 Mvan_3512 113 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 120404795 Common hrcA heat-inducible transcription repressor Mvan_3837 150 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 120401628 Common - Glutamate--ammonia ligase Mvan_0612 223 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 120404479 Common - putative transcriptional regulator, MerR family Mvan_3507 53 COG0789 SoxR, Predicted transcriptional regulators Transcription 120403253 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase Mvan_2262 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 120404991 Nonpathogen - hypothetical protein Mvan_4037 1 None None None 120406190 Common - hypothetical protein Mvan_5242 2 None None None 120407002 Common - methyltransferase GidB Mvan_6073 204 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 120401356 Common - Integral membrane protein TerC Mvan_0331 93 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 120405527 Common - hypothetical protein Mvan_4575 1 None None None 120401361 Common - helix-turn-helix- domain containing protein, AraC type Mvan_0336 65 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 120405343 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mvan_4390 22 None None None 120405131 Common - esterase EstC, putative Mvan_4177 46 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120402353 Common - protein of unknown function DUF732 Mvan_1342 1 None None None 120403991 Common - transcriptional regulator, TetR family Mvan_3009 31 None None None 120404724 Common - Methyltransferase type 12 Mvan_3765 23 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 120403720 Common - cysteine desulfurases, SufS subfamily Mvan_2736 237 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 120403809 Common - acyl-CoA thioesterase Mvan_2825 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 120402322 Common rpsC 30S ribosomal protein S3 Mvan_1311 248 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 120403086 Common - Pyrrolo-quinoline quinone Mvan_2094 4 COG1520 COG1520, FOG: WD40-like repeat Function unknown 120401909 Common - short-chain dehydrogenase/reductase SDR Mvan_0894 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120401269 Common - regulatory protein, LuxR Mvan_0243 38 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 120405316 Nonpathogen - hypothetical protein Mvan_4362 1 None None None 120406385 Common - hypothetical protein Mvan_5438 16 None None None 120402171 Common - sulphate transporter Mvan_1159 156 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 120403678 Common - bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein Mvan_2694 232 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 120404063 Common ureA urease subunit gamma Mvan_3084 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 120402012 Common - nucleotide-binding protein Mvan_0997 107 COG1666 COG1666, Uncharacterized protein conserved in bacteria Function unknown 120406392 Common - methyltransferase small Mvan_5445 22 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 120403338 Common - iron dependent repressor Mvan_2347 106 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 120404707 Nonpathogen - hypothetical protein Mvan_3748 1 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 120403357 Common - Hydrogen:quinone oxidoreductase Mvan_2366 92 COG0374 HyaB, Ni,Fe-hydrogenase I large subunit Energy production and conversion 120403127 Common - isopropylmalate isomerase large subunit Mvan_2135 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 120404683 Common - ErfK/YbiS/YcfS/YnhG family protein Mvan_3723 17 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 120406236 Common - acyl-CoA dehydrogenase domain protein Mvan_5288 101 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120406493 Common - transposase, IS4 family protein Mvan_5550 5 None None None 120403470 Common - hypothetical protein Mvan_2480 18 None None None 120403848 Common - 3-ketosteroid-delta-1-dehydrogenase Mvan_2865 65 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 120401063 Common - hypothetical protein Mvan_0035 49 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 120403432 Common - Peptidoglycan-binding LysM Mvan_2442 1 None None None 120403526 Common - molybdenum ABC transporter, periplasmic molybdate-binding protein Mvan_2538 142 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 120404293 Nonpathogen - hypothetical protein Mvan_3318 1 None None None 120403679 Common ribH riboflavin synthase subunit beta Mvan_2695 216 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 120403883 Common - MMPL domain protein Mvan_2900 44 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 120402269 Common rpoB DNA-directed RNA polymerase subunit beta Mvan_1257 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 120406916 Nonpathogen - hypothetical protein Mvan_5983 1 None None None 120405673 Common - protein of unknown function UPF0089 Mvan_4722 28 None None None 120401151 Common - ABC transporter-related protein Mvan_0123 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 120403608 Common - binding-protein-dependent transport systems inner membrane component Mvan_2623 145 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 120405455 Common glgC glucose-1-phosphate adenylyltransferase Mvan_4503 169 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 120402837 Common - helix-turn-helix- domain containing protein, AraC type Mvan_1839 43 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 120402491 Common - carbohydrate kinase, YjeF related protein Mvan_1482 218 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 120403019 Common ligB ATP-dependent DNA ligase Mvan_2025 105 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 120404881 Common - UbiC transcription regulator-associated domain protein Mvan_3927 126 COG2188 PhnF, Transcriptional regulators Transcription 120406928 Common - hypothetical protein Mvan_5996 30 COG0714 COG0714, MoxR-like ATPases General function prediction only 120404940 Common - lipid-transfer protein Mvan_3986 175 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120403886 Common - protein of unknown function UPF0089 Mvan_2903 27 None None None 120402192 Common - AAA ATPase Mvan_1180 61 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 120401114 Common - hypothetical protein Mvan_0086 1 None None None 120403636 Common - elongation factor P Mvan_2651 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 120405566 Common - hypothetical protein Mvan_4614 5 None None None 120403591 Nonpathogen - hypothetical protein Mvan_2606 1 None None None 120403101 Common - diguanylate cyclase with PAS/PAC sensor Mvan_2109 189 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 120405718 Common - Ppx/GppA phosphatase Mvan_4768 177 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 120401484 Nonpathogen - hypothetical protein Mvan_0460 2 None None None 120402157 Common - putative transcriptional regulator, CopG family Mvan_1145 2 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 120405098 Common - hypothetical protein Mvan_4144 1 None None None 120404784 Nonpathogen - hypothetical protein Mvan_3826 1 COG3590 PepO, Predicted metalloendopeptidase Posttranslational modification, protein turnover, chaperones 120401462 Common - binding-protein-dependent transport systems inner membrane component Mvan_0437 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 120401349 Common - Alpha/beta hydrolase fold-3 domain protein Mvan_0324 108 COG0657 Aes, Esterase/lipase Lipid metabolism 120402124 Common - transposase IS3/IS911 family protein Mvan_1110 59 None None None 120402360 Common - methionine aminopeptidase Mvan_1349 241 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 120402347 Common rpsH 30S ribosomal protein S8 Mvan_1336 243 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 120405818 Nonpathogen - transcriptional regulator, MarR family Mvan_4868 8 COG1846 MarR, Transcriptional regulators Transcription 120406931 Common - nitroreductase Mvan_5999 11 COG0778 NfnB, Nitroreductase Energy production and conversion 120402131 Common - hypothetical protein Mvan_1118 2 None None None 120402155 Common - SEC-C motif domain protein Mvan_1143 10 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 120405143 Common - hypothetical protein Mvan_4189 4 None None None 120403716 Common - putative transcriptional regulator Mvan_2732 30 COG2345 COG2345, Predicted transcriptional regulator Transcription 120404973 Common - thiamine pyrophosphate enzyme domain protein TPP-binding Mvan_4019 221 COG3962 COG3962, Acetolactate synthase Amino acid transport and metabolism 120403541 Common - hypothetical protein Mvan_2554 14 COG4762 COG4762, Uncharacterized protein conserved in bacteria Function unknown 120402791 Common - hypothetical protein Mvan_1792 13 COG4445 MiaE, Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 120403207 Common - ABC transporter-related protein Mvan_2216 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 120404015 Common - hypothetical protein Mvan_3035 57 COG3653 COG3653, N-acyl-D-aspartate/D-glutamate deacylase Secondary metabolites biosynthesis, transport, and catabolism 120401782 Common - Amidohydrolase 3 Mvan_0767 79 COG3653 COG3653, N-acyl-D-aspartate/D-glutamate deacylase Secondary metabolites biosynthesis, transport, and catabolism 120405501 Common phhB pterin-4-alpha-carbinolamine dehydratase Mvan_4549 97 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 120406649 Common - hypothetical protein Mvan_5707 3 None None None 120401705 Common - short chain dehydrogenase Mvan_0690 238 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 120401458 Common - conserved hypothetical proline and threonine rich protein Mvan_0433 125 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 120402457 Common - hypothetical protein Mvan_1446 2 None None None 120404854 Common - Tn554-related, transposase C Mvan_3898 8 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 120402391 Common - Alcohol dehydrogenase GroES domain protein Mvan_1380 204 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 120403749 Common - beta-lactamase Mvan_2765 43 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 120404445 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Mvan_3473 187 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 120406936 Nonpathogen - hypothetical protein Mvan_6004 2 None None None 120404140 Common - putative ammonia monooxygenase Mvan_3161 36 COG3180 AbrB, Putative ammonia monooxygenase General function prediction only 120402578 Common - putative transcriptional regulator, AsnC family Mvan_1571 138 COG1522 Lrp, Transcriptional regulators Transcription 120404778 Common - ferric uptake regulator, Fur family Mvan_3820 185 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 120406999 Common - hypothetical protein Mvan_6070 11 None None None 120402106 Nonpathogen - hypothetical protein Mvan_1092 2 None None None 120401508 Common - Aldehyde dehydrogenase (NAD(+)) Mvan_0486 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 120403919 Common - hypothetical protein Mvan_2936 22 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120401599 Common - transposase IS3/IS911 family protein Mvan_0582 8 None None None 120404540 Common - Glycerate kinase Mvan_3569 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 120404659 Nonpathogen - hypothetical protein Mvan_3697 1 None None None 120405651 Common - hypothetical protein Mvan_4699 59 COG3391 COG3391, Uncharacterized conserved protein Function unknown 120402309 Common - Creatininase Mvan_1298 87 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 120403375 Common - haloalkane dehalogenase Mvan_2384 124 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120402466 Nonpathogen - hypothetical protein Mvan_1456 1 None None None 120406143 Common - hypothetical protein Mvan_5195 4 None None None 120402685 Nonpathogen - hypothetical protein Mvan_1679 1 None None None 120402371 Common - 3-hydroxyisobutyrate dehydrogenase Mvan_1360 187 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 120403742 Common - protein of unknown function DUF107 Mvan_2758 15 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 120405233 Common - alpha/beta hydrolase fold Mvan_4279 199 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120401423 Common - short-chain dehydrogenase/reductase SDR Mvan_0398 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120404384 Common - aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein Mvan_3411 69 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 120406958 Nonpathogen - hypothetical protein Mvan_6027 1 None None None 120401796 Common - putative transmembrane anti-sigma factor Mvan_0781 6 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 120406484 Nonpathogen - hypothetical protein Mvan_5541 1 None None None 120402625 Common - flavoprotein disulfide reductase Mvan_1619 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 120405403 Common - protein of unknown function DUF222 Mvan_4451 7 None None None 120402858 Common - hypothetical protein Mvan_1860 1 None None None 120405913 Common - SMP-30/Gluconolaconase/LRE domain protein Mvan_4964 22 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 120406127 Nonpathogen - hypothetical protein Mvan_5179 1 None None None 120406610 Common - hypothetical protein Mvan_5668 3 None None None 120403850 Common - transcriptional regulator, PadR-like family Mvan_2867 14 COG1695 COG1695, Predicted transcriptional regulators Transcription 120406176 Common - short chain dehydrogenase Mvan_5228 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120405760 Common - arginine deiminase Mvan_4810 51 COG2235 ArcA, Arginine deiminase Amino acid transport and metabolism 120401989 Common - alpha/beta hydrolase fold Mvan_0974 139 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120406918 Nonpathogen - hypothetical protein Mvan_5985 1 None None None 120403489 Common - hypothetical protein Mvan_2500 2 None None None 120406019 Common - cyclase/dehydrase Mvan_5071 7 None None None 120403331 Common - MaoC domain protein dehydratase Mvan_2340 39 COG2030 MaoC, Acyl dehydratase Lipid metabolism 120404675 Common - NLP/P60 protein Mvan_3713 135 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 120401240 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Mvan_0213 161 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 120401982 Common - hypothetical protein Mvan_0967 1 None None None 120404805 Common - beta-ketoacyl synthase Mvan_3847 209 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 120403395 Common - hydrogenase expression/formation protein HypE Mvan_2404 123 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 120405208 Common - acyl-CoA dehydrogenase domain protein Mvan_4254 149 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120403321 Common - putative signal-transduction protein with CBS domains Mvan_2330 73 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 120401549 Common - L-carnitine dehydratase/bile acid-inducible protein F Mvan_0528 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 120405900 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mvan_4951 43 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 120404931 Common - virulence factor Mce family protein Mvan_3977 33 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120402886 Common - Methyltransferase type 11 Mvan_1888 116 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 120405707 Common - hypothetical protein Mvan_4757 2 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 120404572 Common - Enoyl-CoA hydratase/isomerase Mvan_3603 183 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120403117 Common - putative conserved integral membrane alanine and leucine rich protein Mvan_2125 14 None None None 120403897 Nonpathogen - hypothetical protein Mvan_2914 1 None None None 120403467 Common - 1-deoxy-D-xylulose-5-phosphate synthase Mvan_2477 208 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 120401445 Common - protein of unknown function DUF571 Mvan_0420 2 None None None 120403123 Common - major facilitator superfamily MFS_1 Mvan_2131 17 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 120405515 Common - protein of unknown function DUF485 Mvan_4563 55 COG3162 COG3162, Predicted membrane protein Function unknown 120404608 Common - regulatory protein, ArsR Mvan_3640 98 COG0640 ArsR, Predicted transcriptional regulators Transcription 120406581 Common - carboxyl transferase Mvan_5639 191 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 120402233 Common - Radical SAM domain protein Mvan_1221 29 COG2516 COG2516, Biotin synthase-related enzyme General function prediction only 120402333 Common - major facilitator superfamily MFS_1 Mvan_1322 194 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 120405907 Common - acyl-CoA dehydrogenase domain protein Mvan_4958 146 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120406779 Common - Cellulase Mvan_5837 17 COG5297 CelA, Cellobiohydrolase A (1,4-beta-cellobiosidase A) Carbohydrate transport and metabolism 120404911 Common - hypothetical protein Mvan_3957 19 None None None 120403935 Nonpathogen - hypothetical protein Mvan_2952 1 None None None 120405669 Common - hypothetical protein Mvan_4718 2 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 120404839 Common - GTP-binding protein LepA Mvan_3881 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 120402385 Common - heat shock protein Hsp20 Mvan_1374 146 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 120404505 Common - putative conserved transmembrane protein Mvan_3533 16 None None None 120404949 Common - hypothetical protein Mvan_3995 22 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 120401818 Common - Cyclopropane-fatty-acyl-phospholipid synthase Mvan_0803 126 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 120405201 Common - regulatory proteins, IclR Mvan_4247 80 COG1414 IclR, Transcriptional regulator Transcription 120406891 Nonpathogen - hypothetical protein Mvan_5955 1 COG2954 COG2954, Uncharacterized protein conserved in bacteria Function unknown 120404517 Common - hypothetical protein Mvan_3545 3 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 120401166 Common - virulence factor Mce family protein Mvan_0138 12 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120406988 Common - hypothetical protein Mvan_6059 11 None None None 120403658 Common - Endonuclease/exonuclease/phosphatase Mvan_2674 16 COG3021 COG3021, Uncharacterized protein conserved in bacteria Function unknown 120404610 Common - cadmium resistance transporter Mvan_3642 16 COG4300 CadD, Predicted permease, cadmium resistance protein Inorganic ion transport and metabolism 120404903 Common - hypothetical protein Mvan_3949 4 None None None 120404279 Nonpathogen - hypothetical protein Mvan_3304 1 None None None 120406057 Common - glycine cleavage T protein (aminomethyl transferase) Mvan_5109 70 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 120406418 Common - Methyltransferase type 11 Mvan_5471 19 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 120404055 Common - short chain dehydrogenase Mvan_3076 84 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120403130 Common - NUDIX hydrolase Mvan_2138 44 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 120404609 Common - heavy metal translocating P-type ATPase Mvan_3641 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 120402464 Nonpathogen - hypothetical protein Mvan_1454 1 None None None 120406720 Common - short-chain dehydrogenase/reductase SDR Mvan_5778 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120402165 Nonpathogen - hypothetical protein Mvan_1153 1 None None None 120406118 Common - cytochrome P450 Mvan_5170 86 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120404711 Common aceE pyruvate dehydrogenase subunit E1 Mvan_3752 149 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 120402742 Common - Alkane 1-monooxygenase Mvan_1742 27 COG3239 DesA, Fatty acid desaturase Lipid metabolism 120405269 Common - transcriptional regulator, LysR family Mvan_4315 179 COG0583 LysR, Transcriptional regulator Transcription 120406570 Common - short chain dehydrogenase Mvan_5628 96 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 120404215 Common - transcriptional regulator, Fis family Mvan_3238 113 COG0640 ArsR, Predicted transcriptional regulators Transcription 120405277 Common - methylated-DNA--protein-cysteine methyltransferase Mvan_4323 217 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 120405767 Common - shikimate 5-dehydrogenase Mvan_4817 158 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 120406782 Common - hypothetical protein Mvan_5840 11 None None None 120404153 Common - major facilitator superfamily MFS_1 Mvan_3174 62 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120401711 Common - hypothetical protein Mvan_0696 1 None None None 120402908 Common prfB peptide chain release factor 2 Mvan_1911 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 120405310 Nonpathogen - hypothetical protein Mvan_4356 2 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 120404863 Common - transglutaminase, N-terminal domain protein Mvan_3909 95 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 120401211 Common - Neprilysin Mvan_0184 63 COG3590 PepO, Predicted metalloendopeptidase Posttranslational modification, protein turnover, chaperones 120404522 Common - glycosyl transferase, group 1 Mvan_3550 198 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 120402454 Common - protein of unknown function DUF1470 Mvan_1443 20 COG5516 COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding General function prediction only 120403642 Common - beta-lactamase Mvan_2658 138 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 120404002 Common - Pyridoxal-5'-phosphate-dependent enzyme, beta subunit Mvan_3022 204 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 120406108 Common - short chain dehydrogenase Mvan_5160 234 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 120401047 Common - putative septation inhibitor protein Mvan_0019 14 None None None 120402562 Common - alpha/beta hydrolase fold Mvan_1555 45 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120404250 Common cmk cytidylate kinase Mvan_3275 203 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 120406202 Common - MaoC-like dehydratase Mvan_5254 11 None None None 120405430 Common - protein of unknown function DUF732 Mvan_4478 1 None None None 120404617 Common - NLP/P60 protein Mvan_3652 108 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 120404907 Common - Saccharopine dehydrogenase Mvan_3953 38 COG3268 COG3268, Uncharacterized conserved protein Function unknown 120404257 Common - NUDIX hydrolase Mvan_3282 123 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 120406423 Common - VWA containing CoxE family protein Mvan_5477 44 COG3552 CoxE, Protein containing von Willebrand factor type A (vWA) domain General function prediction only 120403449 Nonpathogen - PE_PGRS family protein Mvan_2459 1 None None None 120401113 Common - conserved hypothetical alanine and proline rich protein Mvan_0085 1 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 120404044 Common - hypothetical protein Mvan_3065 16 None None None 120406619 Common - hypothetical protein Mvan_5677 5 None None None 120404580 Common - helix-turn-helix- domain containing protein, AraC type Mvan_3612 153 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 120401281 Common - UspA domain protein Mvan_0255 4 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 120402663 Common - CsbD family protein Mvan_1657 3 None None None 120405214 Common - cobalamin B12-binding domain protein Mvan_4260 109 COG2185 Sbm, Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding) Lipid metabolism 120406459 Common - Choloylglycine hydrolase Mvan_5516 49 COG3049 COG3049, Penicillin V acylase and related amidases Cell envelope biogenesis, outer membrane 120401333 Common - hypothetical protein Mvan_0307 62 COG1738 COG1738, Uncharacterized conserved protein Function unknown 120404893 Common - hypothetical protein Mvan_3939 25 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 120406850 Nonpathogen - hypothetical protein Mvan_5909 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 120404794 Common - chaperone protein DnaJ Mvan_3836 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 120402819 Common - hypothetical protein Mvan_1820 12 None None None 120401288 Common - putative signal transduction histidine kinase Mvan_0262 31 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 120403151 Common - Propeptide, PepSY amd peptidase M4 Mvan_2159 46 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 120403508 Nonpathogen - hypothetical protein Mvan_2520 1 None None None 120401403 Common - precorrin-6x reductase Mvan_0378 51 COG2099 CobK, Precorrin-6x reductase Coenzyme metabolism 120405655 Common - polar amino acid ABC transporter, inner membrane subunit Mvan_4703 185 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 120406907 Common - Integrase, catalytic region Mvan_5973 135 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 120403491 Common - AAA ATPase Mvan_2502 60 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 120403839 Common - virulence factor Mce family protein Mvan_2855 6 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120404007 Common - Serine-type D-Ala-D-Ala carboxypeptidase Mvan_3027 145 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 120402682 Common - hypothetical protein Mvan_1676 1 None None None 120403950 Common - transcriptional regulator, TetR family Mvan_2968 52 COG1309 AcrR, Transcriptional regulator Transcription 120401482 Common - Integrase, catalytic region Mvan_0458 100 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 120403964 Common - Stress responsive alpha-beta barrel domain protein Mvan_2982 6 None None None 120401811 Common - diguanylate cyclase Mvan_0796 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 120403843 Common - hypothetical protein Mvan_2860 2 None None None 120406710 Common - hypothetical protein Mvan_5768 3 None None None 120402448 Common - ribosomal protein L17 Mvan_1437 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 120405572 Common - Methyltransferase type 11 Mvan_4620 58 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 120404082 Common - PE-PPE, C-terminal domain protein Mvan_3103 1 COG4547 CobT, Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase) Coenzyme metabolism 120405863 Common - transcriptional regulator, MarR family Mvan_4913 73 COG1846 MarR, Transcriptional regulators Transcription 120406592 Common - UDP-galactopyranose mutase Mvan_5650 52 COG0562 Glf, UDP-galactopyranose mutase Cell envelope biogenesis, outer membrane 120404162 Common - lipolytic enzyme, G-D-S-L family Mvan_3183 15 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 120403158 Common - putative methyltransferase Mvan_2166 210 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 120406584 Common - cutinase Mvan_5642 4 None None None 120406727 Nonpathogen - hypothetical protein Mvan_5785 2 None None None 120403369 Common - HpcH/HpaI aldolase Mvan_2378 88 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 120406228 Common - molybdopterin dehydrogenase, FAD-binding Mvan_5280 20 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 120405423 Common - LprE Mvan_4471 2 None None None 120405833 Common - DNA-formamidopyrimidine glycosylase Mvan_4883 180 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 120403135 Common ddl D-alanyl-alanine synthetase A Mvan_2143 211 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 120404742 Common - dihydrodipicolinate reductase Mvan_3783 23 COG3804 COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase Function unknown 120401843 Common - hypothetical protein Mvan_0828 10 None None None 120404176 Common - Ethanolamine ammonia lyase large subunit Mvan_3197 55 COG4303 EutB, Ethanolamine ammonia-lyase, large subunit Amino acid transport and metabolism 120403169 Common - signal recognition particle-docking protein FtsY Mvan_2177 246 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 120402570 Common - acyl-CoA synthetase Mvan_1563 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120401692 Common - adenylosuccinate synthetase Mvan_0677 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 120401036 Common - hypothetical protein Mvan_0008 16 COG0392 COG0392, Predicted integral membrane protein Function unknown 120401140 Common - hypothetical protein Mvan_0112 5 COG2839 COG2839, Uncharacterized protein conserved in bacteria Function unknown 120406599 Common - Rieske (2Fe-2S) domain protein Mvan_5657 7 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 120402529 Common - hypothetical protein Mvan_1520 3 None None None 120401295 Common - beta-ketoacyl synthase Mvan_0269 225 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 120404033 Common - Xanthine/uracil/vitamin C permease Mvan_3054 23 COG2252 COG2252, Permeases General function prediction only 120404890 Common - Enoyl-CoA hydratase/isomerase Mvan_3936 180 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120406770 Common - transcriptional regulator, AraC family Mvan_5828 119 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 120402977 Common - AMP-dependent synthetase and ligase Mvan_1981 221 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120402752 Common - two component transcriptional regulator, winged helix family Mvan_1752 212 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 120402364 Common - hypothetical protein Mvan_1353 7 None None None 120406628 Common - hypothetical protein Mvan_5686 10 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120406432 Common - glutamate--cysteine ligase, GCS2 Mvan_5486 53 COG3572 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 120401699 Common - transcriptional regulator, MarR family Mvan_0684 15 COG1846 MarR, Transcriptional regulators Transcription 120401540 Common - hypothetical protein Mvan_0519 5 None None None 120403110 Common - integral membrane sensor signal transduction histidine kinase Mvan_2118 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 120405246 Common - thiamineS protein Mvan_4292 41 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 120405829 Common - transcriptional regulator, XRE family Mvan_4879 50 COG1476 COG1476, Predicted transcriptional regulators Transcription 120405093 Common - thiolase Mvan_4139 94 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120401538 Common - virulence factor Mce family protein Mvan_0517 12 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120403832 Common - short-chain dehydrogenase/reductase SDR Mvan_2848 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120404510 Common - hypothetical protein Mvan_3538 14 None None None 120402483 Common - conserved hypothetical alanine and proline rich protein Mvan_1474 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 120403875 Common - Acyl-CoA dehydrogenase, type 2, C-terminal domain Mvan_2892 47 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120404221 Common - Methyltransferase type 11 Mvan_3244 124 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 120402259 Common - Helix-turn-helix, type 11 domain protein Mvan_1247 34 COG2378 COG2378, Predicted transcriptional regulator Transcription 120406094 Common - RelA/SpoT domain protein Mvan_5146 47 COG4328 COG4328, Uncharacterized protein conserved in bacteria Function unknown 120403828 Common - ABC transporter-related protein Mvan_2844 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 120404942 Common - MaoC domain protein dehydratase Mvan_3988 45 COG2030 MaoC, Acyl dehydratase Lipid metabolism 120402995 Common - hypothetical protein Mvan_2000 16 None None None 120404448 Common - protein of unknown function DUF1214 Mvan_3476 40 COG5361 COG5361, Uncharacterized conserved protein Function unknown 120404963 Common - ABC transporter-related protein Mvan_4009 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 120405743 Nonpathogen - hypothetical protein Mvan_4793 1 None None None 120401899 Common - integral membrane sensor signal transduction histidine kinase Mvan_0884 212 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 120405000 Common - transcriptional regulator, TetR family Mvan_4046 7 COG1309 AcrR, Transcriptional regulator Transcription 120403689 Common tpiA triosephosphate isomerase Mvan_2705 216 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 120403045 Common - hypothetical protein Mvan_2051 11 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 120401727 Common - ABC transporter-related protein Mvan_0712 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 120403345 Common - SEC-C motif domain protein Mvan_2354 88 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 120402394 Common - hypothetical protein Mvan_1383 19 None None None 120406404 Common - hypothetical protein Mvan_5457 9 None None None 120406904 Nonpathogen - hypothetical protein Mvan_5970 1 None None None 120405366 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mvan_4413 36 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 120405756 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Mvan_4806 65 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 120405251 Common - nicotinate phosphoribosyltransferase Mvan_4297 97 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 120401107 Common - 6 kDa early secretory antigenic target EsaT6 (EsaT-6) Mvan_0079 3 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 120405408 Common - histidine triad (HIT) protein Mvan_4456 230 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 120405629 Common - acetyl-CoA acetyltransferase Mvan_4677 184 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120405923 Common - MorD Mvan_4974 43 COG4548 NorD, Nitric oxide reductase activation protein Inorganic ion transport and metabolism 120404884 Common - FAD dependent oxidoreductase Mvan_3930 110 COG0579 COG0579, Predicted dehydrogenase General function prediction only 120405448 Common - RNA polymerase sigma factor SigE Mvan_4496 176 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 120405687 Common - putative outer membrane adhesin like proteiin Mvan_4736 46 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 120403271 Common - Betaine-aldehyde dehydrogenase Mvan_2280 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 120402721 Common - hypothetical protein Mvan_1721 1 None None None 120406683 Common - binding-protein-dependent transport systems inner membrane component Mvan_5741 41 COG4132 COG4132, ABC-type uncharacterized transport system, permease component General function prediction only 120404961 Common - acyl-CoA dehydrogenase domain protein Mvan_4007 129 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120404210 Nonpathogen - hypothetical protein Mvan_3232 3 None None None 120405161 Common - Enoyl-CoA hydratase/isomerase Mvan_4207 180 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120401093 Common - hypothetical protein Mvan_0065 3 None None None 120403892 Common - hypothetical protein Mvan_2909 2 None None None 120402048 Common - protein kinase Mvan_1033 194 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 120406841 Common - protein of unknown function DUF861, cupin_3 Mvan_5899 3 COG3450 COG3450, Predicted enzyme of the cupin superfamily General function prediction only 120403735 Common - von Willebrand factor, type A Mvan_2751 65 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 120405594 Common - hypothetical protein Mvan_4642 8 None None None 120403859 Common - acyl-CoA dehydrogenase domain protein Mvan_2876 158 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120406707 Common - transcriptional regulator, CdaR Mvan_5765 71 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 120401103 Common - cell divisionFtsK/SpoIIIE Mvan_0075 29 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 120403654 Common - S-adenosylmethionine synthetase Mvan_2670 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 120404143 Common - ABC transporter domain protein Mvan_3164 249 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 120403984 Common - putative anti-sigma regulatory factor, serine/threonine protein kinase Mvan_3002 2 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 120401784 Common - hypothetical protein Mvan_0769 14 None None None 120404817 Common - cobalamin (vitamin B12) biosynthesis CbiX protein Mvan_3859 43 COG2138 COG2138, Uncharacterized conserved protein Function unknown 120403680 Common - hypothetical protein Mvan_2696 9 None None None 120403855 Common - Alpha/beta hydrolase fold-3 domain protein Mvan_2872 110 COG0657 Aes, Esterase/lipase Lipid metabolism 120404111 Common - putative transcriptional regulator, MerR family Mvan_3132 23 COG0789 SoxR, Predicted transcriptional regulators Transcription 120401136 Common - haloacid dehalogenase, type II Mvan_0108 35 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 120405532 Common - H+ Antiporter protein Mvan_4580 39 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120403202 Common - sugar transferase Mvan_2211 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 120404170 Common - putative secreted protein Mvan_3191 1 None None None 120403812 Common - ABC transporter, transmembrane region, type 1 Mvan_2828 242 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 120404412 Common - DEAD/DEAH box helicase domain protein Mvan_3440 114 COG4581 COG4581, Superfamily II RNA helicase DNA replication, recombination, and repair 120403808 Common - pyruvate kinase Mvan_2824 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 120405323 Common - hypothetical protein Mvan_4369 1 None None None 120405374 Common - inositol monophosphatase Mvan_4421 108 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 120406745 Common - aminotransferase class-III Mvan_5803 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 120406852 Common - carbohydrate kinase, thermoresistant glucokinase family Mvan_5911 80 COG3265 GntK, Gluconate kinase Carbohydrate transport and metabolism 120405319 Nonpathogen - hypothetical protein Mvan_4365 1 None None None 120402436 Common - UspA domain protein Mvan_1425 49 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 120404625 Common - transposase IS3/IS911 family protein Mvan_3660 56 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 120406167 Common - luciferase family protein Mvan_5219 49 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120402420 Common - Transketolase, central region Mvan_1409 187 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 120403516 Common - hypothetical protein Mvan_2528 12 None None None 120404900 Common rplU 50S ribosomal protein L21 Mvan_3946 214 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 120405488 Common - hypothetical protein Mvan_4536 1 None None None 120403672 Common - Fmu (Sun) domain protein Mvan_2688 197 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 120402035 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Mvan_1020 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 120406284 Common - Arsenical pump membrane protein Mvan_5336 26 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 120404496 Common - cell division protein FtsW Mvan_3524 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 120402983 Common - Enoyl-CoA hydratase/isomerase Mvan_1987 162 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120403663 Common - glycoside hydrolase, family 16 Mvan_2679 45 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 120404285 Common - ornithine carbamoyltransferase Mvan_3310 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 120404828 Common - Methyltransferase type 12 Mvan_3870 43 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 120401073 Common - short-chain dehydrogenase/reductase SDR Mvan_0045 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120402645 Common - hypothetical protein Mvan_1639 1 None None None 120401602 Common - UDP-glucose/GDP-mannose dehydrogenase Mvan_0586 184 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 120401753 Common - putative methyltransferase Mvan_0738 18 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 120404089 Common - PE-PPE, C-terminal domain protein Mvan_3110 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 120403573 Common - peptidyl-prolyl cis-trans isomerase, cyclophilin type Mvan_2588 69 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 120406393 Common - hypothetical protein Mvan_5446 2 None None None 120402314 Common - Carboxylesterase, type B Mvan_1303 70 COG2272 PnbA, Carboxylesterase type B Lipid metabolism 120403160 Common - Hemerythrin HHE cation binding domain protein Mvan_2168 10 COG3945 COG3945, Uncharacterized conserved protein Function unknown 120405256 Common - glycogen branching enzyme Mvan_4302 147 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 120405491 Common - extracellular solute-binding protein, family 5 Mvan_4539 28 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 120402297 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase Mvan_1286 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120405183 Common - L-carnitine dehydratase/bile acid-inducible protein F Mvan_4229 115 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 120405469 Common - amino acid permease-associated region Mvan_4517 159 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 120405105 Common - protein of unknown function DUF140 Mvan_4151 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 120404073 Common - protein of unknown function DUF21 Mvan_3094 218 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 120402510 Common - phospho-2-dehydro-3-heoxyheptonate aldolase Mvan_1501 108 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 120403389 Common - phage shock protein A, PspA Mvan_2398 12 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 120406919 Nonpathogen - hypothetical protein Mvan_5986 1 COG1913 COG1913, Predicted Zn-dependent proteases General function prediction only 120401859 Common hemA glutamyl-tRNA reductase Mvan_0844 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 120404919 Common - pyruvate flavodoxin/ferredoxin oxidoreductase domain protein Mvan_3965 107 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 120406231 Common - transcriptional regulator, TetR family Mvan_5283 138 COG1309 AcrR, Transcriptional regulator Transcription 120401375 Common - flavin reductase domain protein, FMN-binding Mvan_0350 107 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 120406962 Common rpsR 30S ribosomal protein S18 Mvan_6032 210 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 120401200 Common - Lysine exporter protein (LYSE/YGGA) Mvan_0172 119 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 120406972 Common - alpha/beta hydrolase fold Mvan_6042 48 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120405172 Common - acyl-CoA dehydrogenase domain protein Mvan_4218 56 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120403176 Common - Serine-type D-Ala-D-Ala carboxypeptidase Mvan_2184 144 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 120405285 Common - ATP synthase F1, delta subunit Mvan_4331 131 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 120403759 Common - RarD protein, DMT superfamily transporter Mvan_2775 95 COG2962 RarD, Predicted permeases General function prediction only 120405956 Common - ABC transporter-related protein Mvan_5007 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 120401259 Common - phospholipid/glycerol acyltransferase Mvan_0233 27 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 120405609 Common - hypothetical protein Mvan_4657 14 None None None 120406948 Common - hypothetical protein Mvan_6016 3 None None None 120404929 Common - hypothetical protein Mvan_3975 10 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 120403058 Nonpathogen - hypothetical protein Mvan_2064 1 None None None 120401058 Nonpathogen - hypothetical protein Mvan_0030 1 None None None 120402296 Common - hypothetical protein Mvan_1285 1 None None None 120403482 Common - hypothetical protein Mvan_2493 1 None None None 120402113 Nonpathogen - hypothetical protein Mvan_1099 1 None None None 120403531 Common - binding-protein-dependent transport systems inner membrane component Mvan_2543 157 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 120402441 Common - sulfate transporter Mvan_1430 148 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 120401515 Common - aromatic-ring-hydroxylating dioxygenase, beta subunit Mvan_0493 12 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 120406046 Common - hypothetical protein Mvan_5098 5 None None None 120401833 Common - hypothetical protein Mvan_0818 2 COG4325 COG4325, Predicted membrane protein Function unknown 120405153 Common - transcriptional regulator, TetR family Mvan_4199 21 COG1309 AcrR, Transcriptional regulator Transcription 120405238 Common - hypothetical protein Mvan_4284 17 None None None 120402654 Common - ATPase, P-type (transporting), HAD superfamily, subfamily IC Mvan_1648 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 120403249 Common - beta-Ig-H3/fasciclin Mvan_2258 64 COG2335 COG2335, Secreted and surface protein containing fasciclin-like repeats Cell envelope biogenesis, outer membrane 120401173 Nonpathogen - carbon monoxide dehydrogenase subunit G Mvan_0145 3 COG3427 COG3427, Uncharacterized conserved protein Function unknown 120401554 Common - ring hydroxylating dioxygenase, alpha subunit Mvan_0533 81 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 120401433 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mvan_0408 51 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 120402705 Common - Undecaprenyl-phosphate galactose phosphotransferase Mvan_1703 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 120401252 Common - acyl-CoA dehydrogenase domain protein Mvan_0226 119 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120401652 Common - chaperone protein DnaJ Mvan_0636 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 120404367 Common - transcriptional regulator, TetR family Mvan_3393 5 COG1309 AcrR, Transcriptional regulator Transcription 120405772 Common - 3-hydroxyisobutyrate dehydrogenase Mvan_4822 173 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 120405137 Common - hypothetical protein Mvan_4183 4 None None None 120406323 Common - protein of unknown function DUF541 Mvan_5375 93 COG2968 COG2968, Uncharacterized conserved protein Function unknown 120405644 Common - dihydrodipicolinate reductase Mvan_4692 24 COG3804 COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase Function unknown 120402276 Common - formyltetrahydrofolate deformylase Mvan_1265 213 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 120402133 Common - transcriptional regulator, Fis family Mvan_1120 2 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 120403563 Common - hypothetical protein Mvan_2577 3 None None None 120401249 Common - hypothetical protein Mvan_0223 101 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 120405345 Common - acetaldehyde dehydrogenase Mvan_4392 38 COG4569 MhpF, Acetaldehyde dehydrogenase (acetylating) Secondary metabolites biosynthesis, transport, and catabolism 120402941 Common - acyl-CoA dehydrogenase domain protein Mvan_1944 137 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120404477 Common - Chitinase, Cellulase Mvan_3505 78 COG2730 BglC, Endoglucanase Carbohydrate transport and metabolism 120404105 Common - beta-ketoacyl synthase Mvan_3126 209 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 120401566 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mvan_0545 27 None None None 120402672 Nonpathogen - hypothetical protein Mvan_1666 1 None None None 120403087 Common - transferase hexapeptide repeat containing protein Mvan_2095 137 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 120402866 Common - hypothetical protein Mvan_1868 11 None None None 120403585 Common - acyl-CoA dehydrogenase domain protein Mvan_2600 146 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120403926 Common - fatty acid hydroxylase Mvan_2943 12 None None None 120404716 Common - 3-oxoacyl-(acyl carrier protein) synthase II Mvan_3757 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120405795 Common rpmF 50S ribosomal protein L32 Mvan_4845 4 None None None 120402103 Nonpathogen - hypothetical protein Mvan_1089 1 None None None 120403180 Common - hypothetical protein Mvan_2188 53 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 120403801 Common - tryptophan synthase subunit beta Mvan_2817 227 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 120405846 Common - Hydantoinase/oxoprolinase Mvan_4896 98 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120404664 Common - cytochrome c assembly protein Mvan_3702 160 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 120403538 Common - hypothetical protein Mvan_2550 22 COG0778 NfnB, Nitroreductase Energy production and conversion 120404959 Common - enoyl-CoA hydratase Mvan_4005 161 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120401852 Common - pyrroline-5-carboxylate reductase Mvan_0837 206 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 120402844 Common - regulatory protein GntR, HTH Mvan_1846 23 COG2186 FadR, Transcriptional regulators Transcription 120404762 Common - peptidase U62, modulator of DNA gyrase Mvan_3804 166 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 120405222 Common - protein of unknown function DUF35 Mvan_4268 38 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 120406067 Common - phosphoribosylformylglycinamidine synthase II Mvan_5119 234 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 120401221 Common - conserved hypothetical protein 374 Mvan_0194 8 COG0392 COG0392, Predicted integral membrane protein Function unknown 120405058 Common - protein of unknown function UPF0089 Mvan_4104 28 None None None 120404273 Common - transcriptional regulator, TetR family Mvan_3298 56 COG1309 AcrR, Transcriptional regulator Transcription 120404291 Common pheT phenylalanyl-tRNA synthetase subunit beta Mvan_3316 231 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 120405385 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Mvan_4432 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 120406660 Common - glycosyl transferase, group 1 Mvan_5718 195 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 120403065 Common - two component transcriptional regulator, LuxR family Mvan_2073 184 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 120405260 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mvan_4306 95 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 120404419 Common - protein of unknown function DUF1023 Mvan_3447 6 None None None 120406564 Common - hypothetical protein Mvan_5622 9 COG3809 COG3809, Uncharacterized protein conserved in bacteria Function unknown 120404220 Common - regulatory protein, ArsR Mvan_3243 126 COG0640 ArsR, Predicted transcriptional regulators Transcription 120405723 Common - iron permease FTR1 Mvan_4773 97 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 120405051 Common - major facilitator superfamily MFS_1 Mvan_4097 51 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 120402097 Common - major facilitator superfamily MFS_1 Mvan_1083 3 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120403380 Common - two component transcriptional regulator, winged helix family Mvan_2389 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 120404375 Common - beta-lactamase domain protein Mvan_3402 35 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 120404266 Common - hypothetical protein Mvan_3291 1 None None None 120401892 Common - hypothetical protein Mvan_0877 1 None None None 120404460 Common - PEBP family protein Mvan_3488 121 COG1881 COG1881, Phospholipid-binding protein General function prediction only 120403494 Common - hypothetical protein Mvan_2506 2 None None None 120402801 Common - UvrD/REP helicase Mvan_1802 219 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 120404298 Common - short-chain dehydrogenase/reductase SDR Mvan_3324 236 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 120405118 Common - amidohydrolase 2 Mvan_4164 12 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 120401520 Common - protein of unknown function DUF140 Mvan_0498 150 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 120401949 Common - polysaccharide deacetylase Mvan_0934 70 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 120403281 Common - FAD dependent oxidoreductase Mvan_2290 184 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 120405585 Common xseA exodeoxyribonuclease VII large subunit Mvan_4633 203 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 120402126 Common - integrase, catalytic region Mvan_1112 69 None None None 120402875 Common - NADH dehydrogenase subunit I Mvan_1877 196 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 120401398 Common - cytochrome P450 Mvan_0373 81 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120401992 Common - hypothetical protein Mvan_0977 9 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 120404397 Common - transposase, mutator type Mvan_3425 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 120405294 Common - ribosomal protein L31 Mvan_4340 204 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 120406348 Common - hypothetical protein Mvan_5400 1 None None None 120402911 Common - Type II (General) Secretory Pathway (IISP) Family protein Mvan_1914 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 120404840 Common - hypothetical protein Mvan_3882 11 None None None 120403049 Common - geranylgeranyl reductase Mvan_2055 90 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 120405570 Common - hypothetical protein Mvan_4618 11 None None None 120401385 Common - transcriptional regulator, TetR family Mvan_0360 13 COG1309 AcrR, Transcriptional regulator Transcription 120403625 Common alaS alanyl-tRNA synthetase Mvan_2640 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 120406160 Common - LpqN Mvan_5212 1 None None None 120402520 Common - inositol-5-monophosphate dehydrogenase Mvan_1511 241 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 120406896 Nonpathogen - hypothetical protein Mvan_5961 1 None None None 120403034 Common - Glutaredoxin-like protein NrdH Mvan_2040 37 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 120402988 Common - enoyl-CoA hydratase Mvan_1993 177 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120401055 Common - protein phosphatase 2C domain protein Mvan_0027 132 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 120405553 Common - virulence factor Mce family protein Mvan_4601 12 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120401742 Nonpathogen - hypothetical protein Mvan_0727 2 None None None 120402931 Common - TRAP transporter, 4TM/12TM fusion protein Mvan_1934 67 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 120405441 Common - protein of unknown function DUF1003 Mvan_4489 45 COG4420 COG4420, Predicted membrane protein Function unknown 120401863 Common - hypothetical protein Mvan_0848 2 None None None 120403285 Common - cobalt ABC transporter, ATPase subunit Mvan_2294 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 120401308 Common - hypothetical protein Mvan_0282 2 None None None 120404765 Common - transcriptional regulator, MarR family Mvan_3807 43 COG1846 MarR, Transcriptional regulators Transcription 120405241 Common rph ribonuclease PH Mvan_4287 180 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 120404338 Nonpathogen - hypothetical protein Mvan_3364 1 None None None 120406768 Common - nitrile hydratase Mvan_5826 18 None None None 120405806 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase Mvan_4856 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 120402274 Common - methyltransferase FkbM family Mvan_1263 14 None None None 120401556 Nonpathogen - Cupin 2, conserved barrel domain protein Mvan_0535 7 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 120402373 Common - methylmalonate-semialdehyde dehydrogenase Mvan_1362 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 120406020 Common - cyclase/dehydrase Mvan_5072 8 None None None 120401570 Common - ferredoxin Mvan_0549 6 COG1141 Fer, Ferredoxin Energy production and conversion 120405453 Common - Isoprenylcysteine carboxyl methyltransferase Mvan_4501 30 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 120405905 Common - acyl-CoA dehydrogenase domain protein Mvan_4956 137 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120406810 Common - ABC transporter-related protein Mvan_5868 43 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 120405321 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Mvan_4367 27 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 120403312 Common - hypothetical protein Mvan_2321 9 COG4293 COG4293, Uncharacterized protein conserved in bacteria Function unknown 120404643 Nonpathogen - hypothetical protein Mvan_3679 2 None None None 120401226 Common - hypothetical protein Mvan_0199 2 None None None 120406436 Common rpmG 50S ribosomal protein L33 Mvan_5490 129 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 120403909 Nonpathogen - hypothetical protein Mvan_2926 1 None None None 120406004 Common - type III restriction enzyme, res subunit Mvan_5056 83 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 120401956 Common - hypothetical protein Mvan_0941 7 None None None 120402964 Common - hypothetical protein Mvan_1968 58 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 120403797 Common - Redoxin domain protein Mvan_2813 207 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 120401973 Common - protein of unknown function DUF140 Mvan_0958 150 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 120402938 Nonpathogen - hypothetical protein Mvan_1941 2 None None None 120403204 Common - amidase Mvan_2213 216 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 120406325 Common - hypoxanthine phosphoribosyltransferase Mvan_5377 147 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 120401368 Common - hypothetical protein Mvan_0343 11 None None None 120405638 Common - regulatory protein, ArsR Mvan_4686 54 COG0640 ArsR, Predicted transcriptional regulators Transcription 120404353 Common - protein of unknown function DUF222 Mvan_3379 7 None None None 120401467 Common - hypothetical protein Mvan_0442 101 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 120401731 Common - Aminopeptidase Y Mvan_0716 48 COG2234 Iap, Predicted aminopeptidases General function prediction only 120401127 Common - Pirin domain protein Mvan_0099 145 COG1741 COG1741, Pirin-related protein General function prediction only 120406270 Common - 3-mercaptopyruvate sulfurtransferase Mvan_5322 143 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 120404566 Common - (Glutamate--ammonia-ligase) adenylyltransferase Mvan_3597 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 120401861 Common - Uroporphyrinogen III synthase HEM4 Mvan_0846 168 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 120405607 Common - transposase IS116/IS110/IS902 family protein Mvan_4655 30 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 120402726 Common - cell envelope-related transcriptional attenuator Mvan_1726 64 COG1316 LytR, Transcriptional regulator Transcription 120403295 Common - cobyrinic acid a,c-diamide synthase Mvan_2304 136 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 120405807 Common purN phosphoribosylglycinamide formyltransferase Mvan_4857 221 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 120402111 Nonpathogen - hypothetical protein Mvan_1097 1 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 120404503 Common - S-adenosyl-methyltransferase MraW Mvan_3531 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 120401904 Common - oxidoreductase, molybdopterin binding Mvan_0889 50 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 120406469 Common - hypothetical protein Mvan_5526 8 None None None 120406208 Common - hypothetical protein Mvan_5260 2 None None None 120406536 Common - CMP/dCMP deaminase, zinc-binding Mvan_5594 189 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 120406922 Nonpathogen - Mn2+-dependent serine/threonine protein kinase Mvan_5989 2 COG3642 COG3642, Mn2+-dependent serine/threonine protein kinase Signal transduction mechanisms 120404869 Common - competence protein ComEA helix-hairpin-helix repeat protein Mvan_3915 96 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 120401182 Common - O-methyltransferase, family 3 Mvan_0154 115 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 120402014 Common - AMP-dependent synthetase and ligase Mvan_0999 211 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120401971 Nonpathogen - hypothetical protein Mvan_0956 1 None None None 120405151 Common - von Willebrand factor, type A Mvan_4197 43 COG4548 NorD, Nitric oxide reductase activation protein Inorganic ion transport and metabolism 120404192 Common - Cupin 2, conserved barrel domain protein Mvan_3214 12 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 120401317 Common - Endoribonuclease L-PSP Mvan_0291 178 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 120406502 Common - putative esterase Mvan_5560 18 COG0627 COG0627, Predicted esterase General function prediction only 120406145 Common - virulence factor Mce family protein Mvan_5197 16 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120402779 Common - hypothetical protein Mvan_1780 160 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 120402719 Common - acyl-CoA dehydrogenase domain protein Mvan_1719 168 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120405071 Common - hypothetical protein Mvan_4117 3 None None None 120406124 Common - hypothetical protein Mvan_5176 2 None None None 120406420 Common - two component transcriptional regulator, LuxR family Mvan_5474 178 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 120401929 Common - lipoyl synthase Mvan_0914 191 COG0320 LipA, Lipoate synthase Coenzyme metabolism 120401959 Common - short chain dehydrogenase Mvan_0944 215 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 120401747 Common def peptide deformylase Mvan_0732 206 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 120406032 Common - putative transcriptional regulator, TetR family Mvan_5084 9 COG1309 AcrR, Transcriptional regulator Transcription 120405811 Common - glycoside hydrolase, family 8 Mvan_4861 14 COG3405 CelA, Endoglucanase Y Carbohydrate transport and metabolism 120402679 Nonpathogen - hypothetical protein Mvan_1673 1 None None None 120405463 Common - conserved hypothetical protein 730 Mvan_4511 132 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 120402656 Nonpathogen - hypothetical protein Mvan_1650 1 None None None 120405943 Nonpathogen - hypothetical protein Mvan_4994 1 None None None 120404182 Common - phosphate uptake regulator, PhoU Mvan_3204 93 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 120406297 Common - transcriptional regulator, AraC family Mvan_5349 142 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 120403076 Common - putative transcriptional regulator, GntR family Mvan_2084 200 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 120401272 Common - cytochrome P450 Mvan_0246 73 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120406374 Common - peptidase S1 and S6, chymotrypsin/Hap Mvan_5427 4 None None None 120402362 Common - putative transmembrane anti-sigma factor Mvan_1351 10 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 120402775 Common - short chain dehydrogenase Mvan_1776 227 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120402601 Common - protein of unknown function DUF140 Mvan_1595 128 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 120406193 Common - glycosyl transferase, group 1 Mvan_5245 180 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 120406509 Common - microcompartments protein Mvan_5567 18 None None None 120402238 Common - enoyl-CoA hydratase Mvan_1226 45 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120403645 Common pyrC dihydroorotase Mvan_2661 212 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 120404459 Common - dihydroorotate dehydrogenase 2 Mvan_3487 224 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 120403182 Common trmD tRNA (guanine-N(1)-)-methyltransferase Mvan_2190 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 120401702 Common - Rhodanese domain protein Mvan_0687 40 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 120405963 Nonpathogen - hypothetical protein Mvan_5014 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 120406495 Common - hypothetical protein Mvan_5553 6 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 120406662 Common - hypothetical protein Mvan_5720 1 None None None 120406223 Common - uracil-xanthine permease Mvan_5275 136 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 120406511 Common - ethanolamine utilization protein EutN/carboxysome structural protein CcmL Mvan_5569 13 COG4576 CcmL, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 120404735 Common - ABC transporter-related protein Mvan_3776 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 120404530 Common - Rieske (2Fe-2S) domain protein Mvan_3559 27 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 120401910 Common - transcriptional regulator, TetR family Mvan_0895 36 COG1309 AcrR, Transcriptional regulator Transcription 120405787 Nonpathogen - hypothetical protein Mvan_4837 1 None None None 120404223 Nonpathogen - hypothetical protein Mvan_3246 1 None None None 120402877 Common - NADH dehydrogenase subunit G Mvan_1879 196 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 120401497 Common - phage integrase family protein Mvan_0474 195 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 120404750 Common - amino acid/peptide transporter Mvan_3792 80 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 120406072 Common - hypothetical protein Mvan_5124 1 None None None 120404386 Common - binding-protein-dependent transport systems inner membrane component Mvan_3413 193 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 120401392 Common - virulence factor Mce family protein Mvan_0367 6 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120406510 Common - hypothetical protein Mvan_5568 2 None None None 120406026 Common - beta-lactamase domain protein Mvan_5078 51 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 120404977 Common - beta-lactamase domain protein Mvan_4023 199 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 120406482 Common - protein of unknown function DUF6, transmembrane Mvan_5539 50 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 120401207 Common - hypothetical protein Mvan_0179 3 None None None 120401740 Common - thiamine biosynthesis protein ThiC Mvan_0725 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 120403362 Common - hypothetical protein Mvan_2371 1 None None None 120404952 Common - alpha/beta hydrolase fold Mvan_3998 154 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120403165 Common - OsmC family protein Mvan_2173 9 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 120404971 Common - hypothetical protein Mvan_4017 13 COG1830 FbaB, DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes Carbohydrate transport and metabolism 120403496 Common - phage integrase family protein Mvan_2508 45 COG0582 XerC, Integrase DNA replication, recombination, and repair 120404010 Common - transposase, IS4 family protein Mvan_3030 5 None None None 120401897 Common - NAD-dependent epimerase/dehydratase Mvan_0882 126 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 120405077 Common - formate/nitrite family of transporters-like protein Mvan_4123 45 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 120401086 Common - hypothetical protein Mvan_0058 8 None None None 120402260 Nonpathogen - hypothetical protein Mvan_1248 1 None None None 120403571 Common - adenine phosphoribosyltransferase Mvan_2586 166 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 120402600 Common - AMP-dependent synthetase and ligase Mvan_1594 214 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 120403445 Common - hypothetical protein Mvan_2455 1 None None None 120406740 Nonpathogen - putative transmembrane protein Mvan_5798 1 None None None 120403198 Common xerC site-specific tyrosine recombinase XerC Mvan_2207 221 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 120404331 Common - hypothetical protein Mvan_3357 29 COG2339 COG2339, Predicted membrane protein Function unknown 120401277 Common - acyltransferase 3 Mvan_0251 23 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 120405633 Common - enoyl-CoA hydratase Mvan_4681 187 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120402993 Common - acyl-CoA dehydrogenase domain protein Mvan_1998 143 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120404313 Common uvrA excinuclease ABC subunit A Mvan_3339 234 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 120405116 Common - acyl-CoA dehydrogenase domain protein Mvan_4162 144 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120407004 Common - putative inner membrane protein translocase component YidC Mvan_6075 208 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 120405935 Common - NAD-dependent epimerase/dehydratase Mvan_4986 33 COG2910 COG2910, Putative NADH-flavin reductase General function prediction only 120404860 Common - GCN5-related N-acetyltransferase Mvan_3906 18 COG3153 COG3153, Predicted acetyltransferase General function prediction only 120406997 Common - thioredoxin Mvan_6068 234 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 120404662 Common - heavy metal translocating P-type ATPase Mvan_3700 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 120402542 Common - Methyltransferase type 12 Mvan_1534 58 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 120401669 Common - GtrA family protein Mvan_0653 4 COG2246 COG2246, Predicted membrane protein Function unknown 120406402 Common - ATPase associated with various cellular activities, AAA_3 Mvan_5455 178 COG0714 COG0714, MoxR-like ATPases General function prediction only 120403617 Common - Pyruvate, water dikinase Mvan_2632 144 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 120405405 Common - hypothetical protein Mvan_4453 42 COG3663 Mug, G:T/U mismatch-specific DNA glycosylase DNA replication, recombination, and repair 120405556 Common - virulence factor Mce family protein Mvan_4604 6 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120405002 Common - FAD linked oxidase domain protein Mvan_4048 38 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 120402998 Common - molybdopterin oxidoreductase Mvan_2003 175 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 120401613 Common - 4-hydroxy-2-ketovalerate aldolase Mvan_0597 173 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 120403309 Common - Methyltransferase type 11 Mvan_2318 51 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 120404709 Common - hypothetical protein Mvan_3750 16 None None None 120402064 Common - putative GAF sensor protein Mvan_1049 11 None None None 120401800 Common - Prolyl oligopeptidase Mvan_0785 110 COG1505 COG1505, Serine proteases of the peptidase family S9A Amino acid transport and metabolism 120406442 Common - phage integrase family protein Mvan_5497 215 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 120406159 Common - Rieske (2Fe-2S) domain protein Mvan_5211 67 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 120402736 Common - hypothetical protein Mvan_1736 17 None None None 120406566 Common - alkylhydroperoxidase-like protein, AhpD family Mvan_5624 76 COG2128 COG2128, Uncharacterized conserved protein Function unknown 120402808 Common - transcription factor WhiB Mvan_1809 19 None None None 120403022 Common - aminoglycoside phosphotransferase Mvan_2028 60 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 120404017 Common - Amidohydrolase 3 Mvan_3037 57 COG3653 COG3653, N-acyl-D-aspartate/D-glutamate deacylase Secondary metabolites biosynthesis, transport, and catabolism 120405870 Common - hypothetical protein Mvan_4920 1 None None None 120404849 Nonpathogen - hypothetical protein Mvan_3893 2 None None None 120403928 Nonpathogen - hypothetical protein Mvan_2945 4 None None None 120405084 Common - 4-diphosphocytidyl-2C-methyl-D-erythritol synthase Mvan_4130 47 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 120405396 Common - hypothetical protein Mvan_4443 7 None None None 120405823 Common - ATP-dependent DNA helicase PcrA Mvan_4873 230 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 120401399 Common - diguanylate cyclase Mvan_0374 171 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 120404195 Common - regulatory protein, ArsR Mvan_3217 183 COG0640 ArsR, Predicted transcriptional regulators Transcription 120402821 Common - Alpha/beta hydrolase fold-3 domain protein Mvan_1822 38 COG0657 Aes, Esterase/lipase Lipid metabolism 120401411 Common - Xylose isomerase domain protein TIM barrel Mvan_0386 59 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 120405379 Common - glycosyl transferase, family 2 Mvan_4426 112 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 120403422 Common - hypothetical protein Mvan_2432 3 None None None 120401045 Common - Peptidylprolyl isomerase Mvan_0017 198 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 120404318 Common - Cutinase Mvan_3344 3 None None None 120404306 Common - hypothetical protein Mvan_3332 3 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 120404350 Common - Peptidoglycan-binding domain 1 protein Mvan_3376 25 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 120401414 Common - hypothetical protein Mvan_0389 10 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 120401343 Common - transcriptional regulator, TetR family Mvan_0318 86 COG1309 AcrR, Transcriptional regulator Transcription 120401388 Common - virulence factor Mce family protein Mvan_0363 6 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120402710 Common - hypothetical protein Mvan_1709 16 COG4691 StbC, Plasmid stability protein General function prediction only 120406761 Common - luciferase family protein Mvan_5819 91 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120404172 Common - major facilitator superfamily MFS_1 Mvan_3193 54 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120401778 Common - transcriptional regulator, TetR family Mvan_0763 64 COG1309 AcrR, Transcriptional regulator Transcription 120402016 Common - Rieske (2Fe-2S) domain protein Mvan_1001 75 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 120402312 Common - cytochrome P450 Mvan_1301 83 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120403598 Common - hypothetical protein Mvan_2613 1 None None None 120404201 Common - regulatory protein, ArsR Mvan_3223 163 COG0640 ArsR, Predicted transcriptional regulators Transcription 120404539 Common - iron-sulfur cluster assembly accessory protein Mvan_3568 164 COG0316 IscA, Uncharacterized conserved protein Function unknown 120402784 Common - putative conserved integral membrane protein Mvan_1785 5 None None None 120404592 Common cobD cobalamin biosynthesis protein Mvan_3624 152 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 120403669 Common - hypothetical protein Mvan_2685 5 COG4907 COG4907, Predicted membrane protein Function unknown 120403711 Common - transcriptional regulator, TetR family Mvan_2727 50 COG1309 AcrR, Transcriptional regulator Transcription 120403392 Common - UDP-glucuronosyl/UDP-glucosyltransferase Mvan_2401 11 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 120401676 Common - short-chain dehydrogenase/reductase SDR Mvan_0661 202 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 120402145 Common - hypothetical protein Mvan_1132 12 None None None 120402245 Common secE preprotein translocase subunit SecE Mvan_1233 7 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 120406734 Common - hypothetical protein Mvan_5792 12 None None None 120404242 Common - transposase, mutator type Mvan_3267 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 120405401 Common - heavy metal translocating P-type ATPase Mvan_4449 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 120402768 Common - 2,5-didehydrogluconate reductase Mvan_1769 177 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 120402835 Common - hypothetical protein Mvan_1837 3 None None None 120401517 Common - intradiol ring-cleavage dioxygenase Mvan_0495 31 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 120401347 Common - thioesterase superfamily protein Mvan_0322 24 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 120404650 Common - putative adenylate/guanylate cyclase Mvan_3687 2 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 120403706 Common - protein of unknown function DUF1214 Mvan_2722 35 COG5361 COG5361, Uncharacterized conserved protein Function unknown 120401947 Common - permease for cytosine/purines, uracil, thiamine, allantoin Mvan_0932 52 COG1953 FUI1, Cytosine/uracil/thiamine/allantoin permeases Nucleotide transport and metabolism / Coenzyme metabolism 120401342 Common - cytochrome P450 Mvan_0317 77 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120402159 Nonpathogen - hypothetical protein Mvan_1147 2 None None None 120403889 Common - phosphonate ABC transporter, inner membrane subunit Mvan_2906 155 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 120403548 Common - lipid A biosynthesis lauroyl acyltransferase Mvan_2561 55 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 120401854 Nonpathogen - Protein of unknown function DUF1713 Mvan_0839 1 None None None 120402216 Common - conserved hypothetical protein 374 Mvan_1204 7 COG0392 COG0392, Predicted integral membrane protein Function unknown 120405047 Common - hypothetical protein Mvan_4093 2 None None None 120405476 Common - hypothetical protein Mvan_4524 2 None None None 120405564 Common - hypothetical protein Mvan_4612 5 None None None 120402707 Common - hypothetical protein Mvan_1706 42 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 120401374 Common - response regulator receiver protein Mvan_0349 116 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 120404681 Common - Integrase, catalytic region Mvan_3720 145 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 120404472 Common - protein of unknown function DUF112, transmembrane Mvan_3500 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 120401425 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mvan_0400 188 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 120406480 Common - PDZ/DHR/GLGF domain protein Mvan_5537 219 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 120403881 Common - alpha/beta hydrolase fold Mvan_2898 150 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120405421 Common - acyltransferase 3 Mvan_4469 9 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 120405567 Common - hypothetical protein Mvan_4615 2 None None None 120402345 Common rplE 50S ribosomal protein L5 Mvan_1334 248 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 120402544 Common - integral membrane sensor signal transduction histidine kinase Mvan_1536 35 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 120401464 Common - L-lactate dehydrogenase Mvan_0439 167 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 120406647 Common - NAD-dependent epimerase/dehydratase Mvan_5705 175 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 120401506 Common - fumarate reductase/succinate dehydrogenase flavoprotein domain protein Mvan_0484 205 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 120406638 Common - hypothetical protein Mvan_5696 1 None None None 120403524 Common - ABC transporter-related protein Mvan_2536 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 120404065 Common - hypothetical protein Mvan_3086 3 None None None 120402929 Common - anti-sigma-factor antagonist Mvan_1932 1 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 120403370 Common - dienelactone hydrolase Mvan_2379 96 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 120405355 Common - 3-oxoacid CoA-transferase, B subunit Mvan_4402 93 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 120405658 Nonpathogen - hypothetical protein Mvan_4706 1 None None None 120406552 Common - Cytochrome-c oxidase Mvan_5610 172 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 120402985 Common - transcriptional regulator, TetR family Mvan_1989 36 COG1309 AcrR, Transcriptional regulator Transcription 120402611 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Mvan_1605 6 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 120403718 Common - FeS assembly protein SufD Mvan_2734 169 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 120402477 Common - Aldehyde dehydrogenase (NAD(+)) Mvan_1468 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 120403740 Common - formate/nitrite transporter Mvan_2756 98 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 120402627 Common - pseudouridine synthase Mvan_1621 212 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 120403430 Common - LGFP repeat protein Mvan_2440 12 COG5479 COG5479, Uncharacterized protein potentially involved in peptidoglycan biosynthesis Cell envelope biogenesis, outer membrane 120402576 Nonpathogen - hypothetical protein Mvan_1569 1 None None None 120405194 Common - hypothetical protein Mvan_4240 35 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 120406670 Common - isochorismatase hydrolase Mvan_5728 83 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 120403910 Common - AAA ATPase Mvan_2927 60 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 120403789 Common - histidinol-phosphate aminotransferase Mvan_2805 222 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 120401472 Common - hypothetical protein Mvan_0447 2 COG5153 CVT17, Putative lipase essential for disintegration of autophagic bodies inside the vacuole Intracellular trafficking and secretion / Lipid metabolism 120401154 Common - transcriptional regulator, TetR family Mvan_0126 92 COG1309 AcrR, Transcriptional regulator Transcription 120406466 Common - integral membrane sensor signal transduction histidine kinase Mvan_5523 65 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 120401931 Common - acetyl-CoA acetyltransferases Mvan_0916 177 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120405991 Nonpathogen - hypothetical protein Mvan_5042 1 None None None 120402190 Common - amine oxidase Mvan_1178 65 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 120402975 Common - L-carnitine dehydratase/bile acid-inducible protein F Mvan_1979 115 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 120404443 Common hisE phosphoribosyl-ATP pyrophosphatase Mvan_3471 50 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 120403377 Common thyX FAD-dependent thymidylate synthase Mvan_2386 48 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 120401637 Common - conserved hypothetical proline and threonine rich protein Mvan_0621 7 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 120406387 Common - Anion-transporting ATPase Mvan_5440 26 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 120406698 Common - hypothetical protein Mvan_5756 1 None None None 120401937 Common - virulence factor Mce family protein Mvan_0922 6 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120406933 Common - aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Mvan_6001 222 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 120403869 Common - hypothetical protein Mvan_2886 5 None None None 120404270 Common - 3-methyladenine DNA glycosylase Mvan_3295 74 COG2094 Mpg, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 120403941 Common - hypothetical protein Mvan_2958 10 None None None 120401153 Common - hypothetical protein Mvan_0125 1 None None None 120401218 Common - two component transcriptional regulator, winged helix family Mvan_0191 226 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 120405064 Common - dihydroorotate dehydrogenase 2 Mvan_4110 93 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 120402256 Common - transcriptional regulator, TetR family Mvan_1244 12 COG1309 AcrR, Transcriptional regulator Transcription 120403414 Common - protein of unknown function DUF1622 Mvan_2424 26 COG4828 COG4828, Predicted membrane protein Function unknown 120404343 Common - ABC-3 protein Mvan_3369 175 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 120402917 Common - putative short chain dehydrogenase Mvan_1920 13 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120403610 Common - carbohydrate kinase, FGGY Mvan_2625 181 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 120404542 Common cobT nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Mvan_3571 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 120406938 Nonpathogen - hypothetical protein Mvan_6006 2 None None None 120401703 Common - O-succinylhomoserine sulfhydrylase Mvan_0688 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 120402150 Common - HipA domain protein Mvan_1137 54 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 120401799 Nonpathogen - hypothetical protein Mvan_0784 1 None None None 120401794 Common - monooxygenase, FAD-binding Mvan_0779 124 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 120403998 Common - hypothetical protein Mvan_3018 1 None None None 120406955 Common - hypothetical protein Mvan_6024 12 None None None 120404852 Common - phage integrase family protein Mvan_3896 30 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 120405164 Common - acyl-CoA dehydrogenase domain protein Mvan_4210 164 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120406817 Common - phosphonate ABC transporter, inner membrane subunit Mvan_5875 87 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 120402814 Common - transcriptional regulator, putative ATPase, winged helix family Mvan_1815 44 COG3899 COG3899, Predicted ATPase General function prediction only 120401755 Common - putative monovalent cation/H+ antiporter subunit F Mvan_0740 16 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 120406279 Common - hypothetical protein Mvan_5331 5 COG3689 COG3689, Predicted membrane protein Function unknown 120401583 Common - 3-oxoacid CoA-transferase, A subunit Mvan_0564 92 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 120402303 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mvan_1292 53 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 120404989 Common - glycosyltransferase, MGT family Mvan_4035 26 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 120405195 Common - 3-alpha-hydroxysteroid dehydrogenase Mvan_4241 199 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120406171 Common - transcriptional regulator, TetR family Mvan_5223 31 COG1309 AcrR, Transcriptional regulator Transcription 120401290 Nonpathogen - hypothetical protein Mvan_0264 1 None None None 120401498 Common - hypothetical protein Mvan_0475 8 COG3655 COG3655, Predicted transcriptional regulator Transcription 120404998 Common - hypothetical protein Mvan_4044 1 None None None 120403092 Common - electron transfer flavoprotein, alpha subunit Mvan_2100 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 120405529 Common - short-chain dehydrogenase/reductase SDR Mvan_4577 234 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120402081 Common - protein kinase Mvan_1066 149 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 120402924 Common - transcriptional regulator, TetR family Mvan_1927 33 COG1309 AcrR, Transcriptional regulator Transcription 120403660 Common - glycosyl transferase, family 2 Mvan_2676 189 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 120404454 Common - Phosphoglycerate mutase Mvan_3482 104 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 120406526 Common - putative secreted protein Mvan_5584 1 None None None 120402910 Common - hypothetical protein Mvan_1913 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 120403150 Common - protein of unknown function DUF461 Mvan_2158 76 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 120405548 Common - protein of unknown function UPF0089 Mvan_4596 2 None None None 120403782 Common - quinolinate synthetase Mvan_2798 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 120404997 Nonpathogen - hypothetical protein Mvan_4043 2 None None None 120405596 Common - short-chain dehydrogenase/reductase SDR Mvan_4644 231 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 120404776 Common - glycyl-tRNA synthetase Mvan_3818 86 COG0423 GRS1, Glycyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 120406338 Common - hypothetical protein Mvan_5390 7 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 120403453 Common - Inositol-phosphate phosphatase Mvan_2463 162 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 120406548 Common - beta-lactamase domain protein Mvan_5606 43 COG2015 COG2015, Alkyl sulfatase and related hydrolases Secondary metabolites biosynthesis, transport, and catabolism 120404378 Common - hypothetical protein Mvan_3405 8 None None None 120405975 Common - hypothetical protein Mvan_5026 7 None None None 120401877 Common - permease for cytosine/purines, uracil, thiamine, allantoin Mvan_0862 48 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 120401627 Common - Glutamate--ammonia ligase Mvan_0611 224 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 120403697 Nonpathogen - hypothetical protein Mvan_2713 1 None None None 120403951 Common - hypothetical protein Mvan_2969 8 COG3662 COG3662, Uncharacterized protein conserved in bacteria Function unknown 120405616 Common - nuclear transport factor 2 Mvan_4664 10 None None None 120405486 Nonpathogen - hypothetical protein Mvan_4534 1 None None None 120405845 Common - transcriptional regulator, Fis family Mvan_4895 127 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 120406178 Common - regulatory proteins, IclR Mvan_5230 51 COG1414 IclR, Transcriptional regulator Transcription 120401718 Common - protein kinase Mvan_0703 137 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 120403452 Common - Polyphosphate--glucose phosphotransferase Mvan_2462 80 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 120403236 Common - hypothetical protein Mvan_2245 1 None None None 120402537 Common - MaoC domain protein dehydratase Mvan_1528 33 COG2030 MaoC, Acyl dehydratase Lipid metabolism 120406860 Nonpathogen - hypothetical protein Mvan_5920 1 COG2339 COG2339, Predicted membrane protein Function unknown 120401651 Common - GrpE protein Mvan_0635 59 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 120402958 Common - hypothetical protein Mvan_1962 5 None None None 120401630 Common - short-chain dehydrogenase/reductase SDR Mvan_0614 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120402396 Common - heavy metal translocating P-type ATPase Mvan_1385 231 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 120406650 Common - methionine-R-sulfoxide reductase Mvan_5708 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 120406310 Common - pantothenate kinase Mvan_5362 116 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 120402209 Common - hypothetical protein Mvan_1197 39 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 120404752 Common - hypothetical protein Mvan_3794 1 COG3898 COG3898, Uncharacterized membrane-bound protein Function unknown 120404722 Common - hypothetical protein Mvan_3763 17 None None None 120403355 Common - hypothetical protein Mvan_2364 3 COG2427 COG2427, Uncharacterized conserved protein Function unknown 120403439 Common - hypothetical protein Mvan_2449 6 None None None 120406214 Common - enoyl-CoA hydratase Mvan_5266 155 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120403821 Common - hypothetical protein Mvan_2837 4 COG5373 COG5373, Predicted membrane protein Function unknown 120406755 Common - metallophosphoesterase Mvan_5813 89 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 120402455 Common - protein of unknown function DUF690 Mvan_1444 8 None None None 120402830 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mvan_1831 110 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 120404487 Common - DivIVA family protein Mvan_3515 40 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 120406800 Common - protein of unknown function DUF305 Mvan_5858 41 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 120404482 Common - beta-lactamase Mvan_3510 113 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 120404771 Common - hypothetical protein Mvan_3813 1 None None None 120401725 Common thiG thiazole synthase Mvan_0710 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 120402854 Common - aldehyde dehydrogenase Mvan_1856 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 120401061 Common - hypothetical protein Mvan_0033 2 None None None 120406832 Common - Activator of Hsp90 ATPase 1 family protein Mvan_5890 10 COG3832 COG3832, Uncharacterized conserved protein Function unknown 120405009 Common - CMP/dCMP deaminase, zinc-binding Mvan_4055 173 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 120403726 Common - ABC transporter-related protein Mvan_2742 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 120404802 Common - amino acid adenylation domain Mvan_3844 213 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 120401328 Common - GCN5-related N-acetyltransferase Mvan_0302 6 None None None 120401231 Common - hypothetical protein Mvan_0204 98 COG0579 COG0579, Predicted dehydrogenase General function prediction only 120404436 Common - hypothetical protein Mvan_3464 17 None None None 120402684 Common - Endonuclease/exonuclease/phosphatase Mvan_1678 12 COG3021 COG3021, Uncharacterized protein conserved in bacteria Function unknown 120403774 Common bioD dithiobiotin synthetase Mvan_2790 78 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 120406334 Common - non-ribosomal peptide synthetase Mvan_5386 180 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 120402898 Common - transcriptional regulator, TetR family Mvan_1901 31 COG1309 AcrR, Transcriptional regulator Transcription 120405503 Nonpathogen - hypothetical protein Mvan_4551 1 None None None 120402498 Common - O-sialoglycoprotein endopeptidase Mvan_1489 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 120403084 Common - immunogenic protein MPB64/MPT64 precursor Mvan_2092 3 None None None 120402355 Common - putative methyltransferase Mvan_1344 27 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 120402565 Common - hypothetical protein Mvan_1558 5 None None None 120402320 Common rpsS 30S ribosomal protein S19 Mvan_1309 240 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 120406809 Common - hypothetical protein Mvan_5867 52 COG3454 COG3454, Metal-dependent hydrolase involved in phosphonate metabolism Inorganic ion transport and metabolism 120401591 Common - Integrase, catalytic region Mvan_0573 102 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 120403012 Common - luciferase family protein Mvan_2018 33 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120401199 Nonpathogen - hypothetical protein Mvan_0171 1 None None None 120404799 Common - hypothetical protein Mvan_3841 2 None None None 120405189 Common - putative ferredoxin Mvan_4235 13 COG1141 Fer, Ferredoxin Energy production and conversion 120403535 Common - hypothetical protein Mvan_2547 23 None None None 120401625 Common - short-chain dehydrogenase/reductase SDR Mvan_0609 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120403783 Common - L-aspartate oxidase Mvan_2799 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 120402638 Common - DEAD/H associated domain protein Mvan_1632 227 COG1201 Lhr, Lhr-like helicases General function prediction only 120402248 Common rplA 50S ribosomal protein L1 Mvan_1236 247 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 120403178 Common - hypothetical protein Mvan_2186 10 None None None 120403222 Common - hypothetical protein Mvan_2231 9 None None None 120401053 Common - penicillin-binding protein, transpeptidase Mvan_0025 205 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 120403280 Common - aminoglycoside phosphotransferase Mvan_2289 17 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 120403736 Common - 3-oxoacyl-(acyl-carrier-protein) reductase Mvan_2752 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120405878 Common - hypothetical protein Mvan_4928 13 COG5343 COG5343, Uncharacterized protein conserved in bacteria Function unknown 120405059 Common - PfkB domain protein Mvan_4105 97 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 120405425 Common - FAD linked oxidase domain protein Mvan_4473 198 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 120401253 Common - Alpha/beta hydrolase fold-3 domain protein Mvan_0227 69 COG0657 Aes, Esterase/lipase Lipid metabolism 120404803 Common - amino acid adenylation domain Mvan_3845 211 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 120404241 Common - IstB domain protein ATP-binding protein Mvan_3265 101 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 120405646 Common - lipid-transfer protein Mvan_4694 173 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120404475 Common - signal transduction histidine kinase regulating citrate/malate metabolism Mvan_3503 199 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 120406789 Common - ferredoxin-dependent glutamate synthase Mvan_5847 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 120403725 Common - enoyl-CoA hydratase Mvan_2741 171 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120404760 Common - hypothetical protein Mvan_3802 13 COG2128 COG2128, Uncharacterized conserved protein Function unknown 120401175 Common - Pirin domain protein domain protein Mvan_0147 147 COG1741 COG1741, Pirin-related protein General function prediction only 120404127 Common - amine oxidase Mvan_3148 15 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 120402388 Common - hypothetical protein Mvan_1377 14 None None None 120404494 Common murC UDP-N-acetylmuramate--L-alanine ligase Mvan_3522 208 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 120406555 Common - enoyl-CoA hydratase Mvan_5613 170 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120404050 Common - protein of unknown function DUF1470 Mvan_3071 26 COG5516 COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding General function prediction only 120403533 Common - periplasmic binding protein/LacI transcriptional regulator Mvan_2545 126 COG1609 PurR, Transcriptional regulators Transcription 120402502 Common - short-chain dehydrogenase/reductase SDR Mvan_1493 231 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 120401391 Common - virulence factor Mce family protein Mvan_0366 6 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120402804 Common nudC NADH pyrophosphatase Mvan_1805 105 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 120405777 Common - protein of unknown function DUF222 Mvan_4827 7 None None None 120403488 Nonpathogen - hypothetical protein Mvan_2499 1 None None None 120402112 Common - SMC domain protein Mvan_1098 20 COG4717 COG4717, Uncharacterized conserved protein Function unknown 120404092 Common - short-chain dehydrogenase/reductase SDR Mvan_3113 233 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 120404619 Common - hypothetical protein Mvan_3654 14 COG4219 MecR1, Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component Transcription / Signal transduction mechanisms 120405750 Common ksgA dimethyladenosine transferase Mvan_4800 247 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 120404196 Common - secreted protein Mvan_3218 31 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 120404665 Nonpathogen - hypothetical protein Mvan_3703 1 None None None 120403188 Common - HAD-superfamily hydrolase, subfamily IIA Mvan_2196 109 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 120406799 Common - hypothetical protein Mvan_5857 1 None None None 120401578 Common - regulatory proteins, IclR Mvan_0559 121 COG1414 IclR, Transcriptional regulator Transcription 120402118 Common - hypothetical protein Mvan_1104 1 None None None 120401108 Common - conserved hypothetical proline and alanine rich protein Mvan_0080 40 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 120401619 Common - glucose-1-phosphate thymidylyltransferase Mvan_0603 232 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 120406169 Common - lipid-transfer protein Mvan_5221 21 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120406633 Common - hypothetical protein Mvan_5691 1 None None None 120403627 Common - aminodeoxychorismate lyase Mvan_2642 183 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 120401894 Common - ATPase associated with various cellular activities, AAA_3 Mvan_0879 174 COG0714 COG0714, MoxR-like ATPases General function prediction only 120404264 Common ppnK inorganic polyphosphate/ATP-NAD kinase Mvan_3289 236 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 120401592 Common - transposase, IS4 family protein Mvan_0574 25 COG5421 COG5421, Transposase DNA replication, recombination, and repair 120405145 Common - short-chain dehydrogenase/reductase SDR Mvan_4191 232 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120402957 Common - transcriptional regulator, TetR family Mvan_1961 42 COG1309 AcrR, Transcriptional regulator Transcription 120406769 Nonpathogen - hypothetical protein Mvan_5827 6 None None None 120405737 Common - 50S ribosomal protein L25/general stress protein Ctc Mvan_4787 184 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 120403687 Common - glyceraldehyde-3-phosphate dehydrogenase, type I Mvan_2703 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 120401567 Common - ring hydroxylating dioxygenase, alpha subunit Mvan_0546 82 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 120401668 Common - regulatory protein Mvan_0652 79 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 120401184 Common - FAD linked oxidase domain protein Mvan_0156 44 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 120405885 Common - putative transcriptional regulator, MerR family Mvan_4935 114 COG0789 SoxR, Predicted transcriptional regulators Transcription 120401360 Common - hypothetical protein Mvan_0335 1 None None None 120405824 Common - chorismate mutase Mvan_4874 8 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 120401434 Common - FadD27 Mvan_0409 4 None None None 120405728 Common - transcriptional regulator, TetR family Mvan_4778 127 COG1309 AcrR, Transcriptional regulator Transcription 120402095 Common - peptide synthase Mvan_1080 207 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120405928 Common - cytochrome P450 Mvan_4979 79 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120401715 Common - phosphate acetyltransferase Mvan_0700 171 COG0280 Pta, Phosphotransacetylase Energy production and conversion 120403383 Common - Antibiotic biosynthesis monooxygenase Mvan_2392 16 COG1359 COG1359, Uncharacterized conserved protein Function unknown 120405225 Common - NAD-dependent epimerase/dehydratase Mvan_4271 189 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 120405653 Nonpathogen - CsbD family protein Mvan_4701 1 None None None 120402930 Common - hypothetical protein Mvan_1933 65 COG3285 COG3285, Predicted eukaryotic-type DNA primase DNA replication, recombination, and repair 120406186 Common - MaoC domain protein dehydratase Mvan_5238 27 COG2030 MaoC, Acyl dehydratase Lipid metabolism 120404657 Common - ErfK/YbiS/YcfS/YnhG family protein Mvan_3694 23 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 120405508 Common - HhH-GPD family protein Mvan_4556 11 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 120403378 Common - dihydrodipicolinate synthase Mvan_2387 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 120406847 Common - two component transcriptional regulator, LuxR family Mvan_5906 171 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 120403587 Common - amidohydrolase 2 Mvan_2602 20 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 120405721 Common eno phosphopyruvate hydratase Mvan_4771 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 120406567 Common - putative transcriptional regulator, GntR family Mvan_5625 176 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 120402273 Common - phosphoesterase, PA-phosphatase related Mvan_1262 3 None None None 120403461 Common - hypothetical protein Mvan_2471 17 None None None 120403137 Common - Tn554 transposase C Mvan_2145 7 None None None 120402935 Nonpathogen - hypothetical protein Mvan_1938 1 None None None 120401192 Nonpathogen - hypothetical protein Mvan_0164 1 None None None 120401979 Common - Mammalian cell entry related domain protein Mvan_0964 6 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120403248 Common - Deoxyribodipyrimidine photo-lyase Mvan_2257 136 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 120404251 Common - pseudouridine synthase Mvan_3276 205 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 120405254 Common - alpha-glucan phosphorylases Mvan_4300 149 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 120401300 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Mvan_0274 13 None None None 120403347 Common - putative transcriptional regulator, AsnC family Mvan_2356 150 COG1522 Lrp, Transcriptional regulators Transcription 120404114 Common - FHA domain containing protein Mvan_3135 67 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 120402243 Common - MaoC domain protein dehydratase Mvan_1231 61 COG2030 MaoC, Acyl dehydratase Lipid metabolism 120406033 Common - fatty acid desaturase, type 2 Mvan_5085 10 None None None 120404444 Common - sugar transporter Mvan_3472 106 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120401071 Common - amino acid permease-associated region Mvan_0043 170 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 120403890 Common - Alcohol dehydrogenase GroES domain protein Mvan_2907 201 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 120406717 Common - hypothetical protein Mvan_5775 32 None None None 120401536 Common - virulence factor Mce family protein Mvan_0515 22 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120405535 Common - NAD-dependent epimerase/dehydratase Mvan_4583 71 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 120401138 Common - hypothetical protein Mvan_0110 47 COG3665 COG3665, Uncharacterized conserved protein Function unknown 120404586 Common - hypothetical protein Mvan_3618 180 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 120405035 Common - PE-PPE, C-terminal domain protein Mvan_4081 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 120401809 Common - dihydrolipoamide dehydrogenase Mvan_0794 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 120404057 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mvan_3078 177 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 120406496 Nonpathogen - hypothetical protein Mvan_5554 3 None None None 120405496 Common - nitrate reductase molybdenum cofactor assembly chaperone Mvan_4544 21 COG2180 NarJ, Nitrate reductase delta subunit Energy production and conversion 120405257 Common - Thioredoxin domain Mvan_4303 100 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 120406139 Common - hypothetical protein Mvan_5191 3 None None None 120406902 Common - response regulator receiver protein Mvan_5967 6 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 120402731 Common - NUDIX hydrolase Mvan_1731 22 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 120402963 Common - diguanylate cyclase/phosphodiesterase with GAF sensor Mvan_1967 177 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 120403806 Common - Glutamate synthase (ferredoxin) Mvan_2822 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 120406062 Common - amidophosphoribosyltransferase Mvan_5114 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 120402718 Common - putative outer membrane adhesin like proteiin Mvan_1718 25 COG3961 COG3961, Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only 120406942 Nonpathogen - hypothetical protein Mvan_6010 1 None None None 120403292 Common - GCN5-related N-acetyltransferase Mvan_2301 81 COG2153 ElaA, Predicted acyltransferase General function prediction only 120405983 Common - hypothetical protein Mvan_5034 17 None None None 120405958 Common - two component transcriptional regulator, winged helix family Mvan_5009 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 120406709 Common - hypothetical protein Mvan_5767 1 None None None 120401681 Common - glycoside hydrolase, family 76 Mvan_0666 10 COG4833 COG4833, Predicted glycosyl hydrolase Carbohydrate transport and metabolism 120401095 Common - transcription factor WhiB Mvan_0067 1 None None None 120404408 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Mvan_3436 8 None None None 120403830 Common - protein of unknown function DUF167 Mvan_2846 15 COG1872 COG1872, Uncharacterized conserved protein Function unknown 120403620 Common - recombination factor protein RarA Mvan_2635 245 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 120406016 Common - hypothetical protein Mvan_5068 2 None None None 120405816 Common - acetyl-CoA acetyltransferase Mvan_4866 14 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120402884 Common - response regulator receiver protein Mvan_1886 11 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 120404638 Common - two component transcriptional regulator, winged helix family Mvan_3674 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 120405741 Common - OsmC family protein Mvan_4791 33 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 120403554 Common - acyl-CoA dehydrogenase domain protein Mvan_2567 149 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120405175 Common - cytochrome P450 Mvan_4221 87 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120401382 Nonpathogen - Limonene-1,2-epoxide hydrolase Mvan_0357 2 COG4308 LimA, Limonene-1,2-epoxide hydrolase Secondary metabolites biosynthesis, transport, and catabolism 120404944 Common - Enoyl-CoA hydratase/isomerase Mvan_3990 178 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120404887 Common - ATPase associated with various cellular activities, AAA_5 Mvan_3933 128 COG0714 COG0714, MoxR-like ATPases General function prediction only 120401222 Common - protein of unknown function UPF0118 Mvan_0195 114 COG0628 PerM, Predicted permease General function prediction only 120402841 Common - bifunctional deaminase-reductase domain protein Mvan_1843 51 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 120402266 Common - ABC transporter-related protein Mvan_1254 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 120404365 Common - hypothetical protein Mvan_3391 3 None None None 120405832 Common - transposase IS116/IS110/IS902 family protein Mvan_4882 30 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 120403825 Common - Extracellular ligand-binding receptor Mvan_2841 130 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 120404623 Nonpathogen - hypothetical protein Mvan_3658 1 None None None 120401786 Common - aldehyde dehydrogenase Mvan_0771 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 120404538 Common - putative conserved membrane protein Mvan_3567 1 None None None 120401441 Common - transposase IS116/IS110/IS902 family protein Mvan_0416 93 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 120405107 Common - thiolase family protein Mvan_4153 90 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120404780 Common - undecaprenyl diphosphate synthase Mvan_3822 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 120402984 Common - acetyl-CoA acetyltransferases Mvan_1988 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120406684 Common - extracellular solute-binding protein, family 1 Mvan_5742 51 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 120401358 Nonpathogen - hypothetical protein Mvan_0333 1 None None None 120403518 Common - anti-sigma-factor antagonist Mvan_2530 1 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 120406363 Common - hypothetical protein Mvan_5416 1 None None None 120401560 Common - Rieske (2Fe-2S) domain protein Mvan_0539 81 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 120401661 Common - hypothetical protein Mvan_0645 13 COG5446 COG5446, Predicted integral membrane protein Function unknown 120403686 Common - extracellular solute-binding protein, family 3 Mvan_2702 147 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 120406996 Common - thioredoxin reductase Mvan_6067 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 120405236 Nonpathogen - hypothetical protein Mvan_4282 3 None None None 120404513 Common - hypothetical protein Mvan_3541 9 None None None 120406116 Common - short-chain dehydrogenase/reductase SDR Mvan_5168 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120403162 Common - protein of unknown function DUF177 Mvan_2170 43 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 120406059 Common - phosphoribosylaminoimidazole synthetase Mvan_5111 227 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 120401190 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Mvan_0162 117 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 120402583 Common - hypothetical protein Mvan_1576 22 COG2128 COG2128, Uncharacterized conserved protein Function unknown 120405371 Nonpathogen - hypothetical protein Mvan_4418 1 None None None 120404964 Common - inner-membrane translocator Mvan_4010 112 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 120404640 Common - protein of unknown function DUF305 Mvan_3676 28 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 120406884 Nonpathogen - hypothetical protein Mvan_5948 1 None None None 120403393 Common - hypothetical protein Mvan_2402 13 None None None 120404416 Common - hypothetical protein Mvan_3444 35 COG2378 COG2378, Predicted transcriptional regulator Transcription 120406050 Common - protein of unknown function DUF1416 Mvan_5102 10 None None None 120402879 Common - NADH dehydrogenase subunit E Mvan_1881 155 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 120402445 Common - 30S ribosomal protein S11 Mvan_1434 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 120402642 Common - hypothetical protein Mvan_1636 6 None None None 120406209 Common - hypothetical protein Mvan_5261 11 None None None 120403460 Common - nucleic acid binding, OB-fold, tRNA/helicase-type Mvan_2470 12 None None None 120406064 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Mvan_5116 4 None None None 120402481 Common - phosphoglucosamine mutase Mvan_1472 238 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 120404087 Common - cytochrome P450 Mvan_3108 78 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120404099 Common - ABC drug efflux pump, inner membrane subunit, DrrB family Mvan_3120 22 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 120405182 Common - short-chain dehydrogenase/reductase SDR Mvan_4228 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120402504 Common groEL chaperonin GroEL Mvan_1495 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 120403259 Common - hypothetical protein Mvan_2268 18 None None None 120405493 Common - hypothetical protein Mvan_4541 1 None None None 120404154 Common - 4-alpha-glucanotransferase Mvan_3175 118 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 120405765 Common - PE-PPE, C-terminal domain protein Mvan_4815 1 COG4223 COG4223, Uncharacterized protein conserved in bacteria Function unknown 120403056 Nonpathogen - hypothetical protein Mvan_2062 1 None None None 120406623 Nonpathogen - hypothetical protein Mvan_5681 1 None None None 120405871 Common - short chain dehydrogenase Mvan_4921 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120405216 Common - short chain dehydrogenase Mvan_4262 179 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120404858 Common - phage integrase family protein Mvan_3903 5 None None None 120404558 Common - phage integrase family protein Mvan_3589 215 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 120406043 Common - arsenite-activated ATPase ArsA Mvan_5095 95 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 120402451 Common - cutinase Mvan_1440 4 COG0400 COG0400, Predicted esterase General function prediction only 120406181 Common - ATP-dependent DNA helicase, RecQ family Mvan_5233 218 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 120401387 Common - protein of unknown function DUF140 Mvan_0362 149 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 120406005 Common - hypothetical protein Mvan_5057 84 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 120404905 Common valS valyl-tRNA synthetase Mvan_3951 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 120405543 Common - hypothetical protein Mvan_4591 5 None None None 120404529 Common - cytochrome c, class I Mvan_3558 25 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 120404932 Common - virulence factor Mce family protein Mvan_3978 16 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120405730 Common - D-amino-acid dehydrogenase Mvan_4780 101 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 120402408 Common - hypothetical protein Mvan_1397 1 None None None 120402573 Common - hypothetical protein Mvan_1566 1 None None None 120404899 Common rpmA 50S ribosomal protein L27 Mvan_3945 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 120405207 Common - Enoyl-CoA hydratase/isomerase Mvan_4253 150 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120405930 Common - dihydrodipicolinate reductase Mvan_4981 14 COG3804 COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase Function unknown 120401310 Common sdhA succinate dehydrogenase flavoprotein subunit Mvan_0284 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 120404520 Common - hypothetical protein Mvan_3548 4 None None None 120405337 Common - C4-dicarboxylate transporter/malic acid transport protein Mvan_4384 26 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 120404463 Common - molybdopterin oxidoreductase Mvan_3491 203 COG0369 CysJ, Sulfite reductase, alpha subunit (flavoprotein) Inorganic ion transport and metabolism 120404927 Common - putative GAF sensor protein Mvan_3973 126 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 120406105 Common - aldehyde dehydrogenase Mvan_5157 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 120402479 Common - ribosomal protein S9 Mvan_1470 219 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 120406590 Common - phosphoesterase, PA-phosphatase related Mvan_5648 5 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 120401911 Nonpathogen - transcriptional regulator Mvan_0896 4 COG1414 IclR, Transcriptional regulator Transcription 120405447 Common - hypothetical protein Mvan_4495 6 None None None 120406690 Common - General substrate transporter Mvan_5748 124 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120406200 Common - glycosyl transferase, group 1 Mvan_5252 52 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 120404080 Common - short-chain dehydrogenase/reductase SDR Mvan_3101 236 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 120406419 Common - Methyltransferase type 11 Mvan_5473 6 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 120406098 Common - phosphoribosylamine--glycine ligase Mvan_5150 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 120401835 Nonpathogen - hypothetical protein Mvan_0820 1 None None None 120401767 Common - molybdenum cofactor synthesis domain Mvan_0752 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 120403429 Common - Long-chain-acyl-CoA dehydrogenase Mvan_2439 163 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120401908 Common - isochorismatase hydrolase Mvan_0893 67 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 120403990 Common - helix-turn-helix- domain containing protein, AraC type Mvan_3008 132 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 120404527 Common trpD anthranilate phosphoribosyltransferase Mvan_3556 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 120402094 Common - alpha/beta hydrolase fold Mvan_1079 152 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120406488 Common - hypothetical protein Mvan_5545 9 COG5522 COG5522, Predicted integral membrane protein Function unknown 120401470 Common - Lipocalin family protein Mvan_0445 70 COG3040 Blc, Bacterial lipocalin Cell envelope biogenesis, outer membrane 120406242 Common - xylose isomerase Mvan_5294 76 COG2115 XylA, Xylose isomerase Carbohydrate transport and metabolism 120404470 Common - hypothetical protein Mvan_3498 3 None None None 120402728 Common - glycosyl transferase, family 2 Mvan_1728 124 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 120403937 Common - putative esterase Mvan_2954 17 COG0627 COG0627, Predicted esterase General function prediction only 120405574 Common - hypothetical protein Mvan_4622 27 COG5649 COG5649, Uncharacterized conserved protein Function unknown 120404356 Common - TspO and MBR like proteins Mvan_3382 14 COG3476 COG3476, Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) Signal transduction mechanisms 120402665 Common - putative anti-sigma regulatory factor, serine/threonine protein kinase Mvan_1659 11 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 120401522 Common - virulence factor Mce family protein Mvan_0500 8 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120403923 Common - PilT protein domain protein Mvan_2940 39 COG3744 COG3744, Uncharacterized protein conserved in bacteria Function unknown 120405112 Common - short-chain dehydrogenase/reductase SDR Mvan_4158 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120403609 Common - extracellular solute-binding protein, family 1 Mvan_2624 108 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 120403616 Common - hypothetical protein Mvan_2631 31 COG4307 COG4307, Uncharacterized protein conserved in bacteria Function unknown 120401853 Common - DNA binding domain, excisionase family Mvan_0838 20 None None None 120406986 Common - hypothetical protein Mvan_6057 121 COG1678 COG1678, Putative transcriptional regulator Transcription 120401840 Common - short-chain dehydrogenase/reductase SDR Mvan_0825 233 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 120402423 Common - peptidase M50 Mvan_1412 36 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 120406596 Common - Cof-like hydrolase Mvan_5654 123 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 120402010 Common - NAD(P)H-dependent glycerol-3-phosphate dehydrogenase Mvan_0995 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 120402527 Common - putative transcriptional regulator, MerR family Mvan_1518 15 COG0789 SoxR, Predicted transcriptional regulators Transcription 120405364 Common - regulatory proteins, IclR Mvan_4411 120 COG1414 IclR, Transcriptional regulator Transcription 120403157 Common - pyruvate carboxylase Mvan_2165 238 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 120401099 Common - hypothetical protein Mvan_0071 1 None None None 120402713 Common - GtrA family protein Mvan_1712 11 COG2246 COG2246, Predicted membrane protein Function unknown 120404036 Common - Tetratricopeptide TPR_2 repeat protein Mvan_3057 26 None None None 120404423 Common - protein of unknown function DUF245 domain protein Mvan_3451 16 None None None 120404024 Common - BFD domain protein (2Fe-2S)-binding domain protein Mvan_3045 1 COG2906 Bfd, Bacterioferritin-associated ferredoxin Inorganic ion transport and metabolism 120401605 Common dcd deoxycytidine triphosphate deaminase Mvan_0589 161 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 120402552 Common - hypothetical protein Mvan_1545 25 None None None 120402754 Common - LpqB Mvan_1754 17 None None None 120401671 Common - hypothetical protein Mvan_0656 1 None None None 120404428 Nonpathogen - hypothetical protein Mvan_3456 1 None None None 120404836 Common - hypothetical protein Mvan_3878 1 None None None 120401646 Common - hypothetical protein Mvan_0630 15 None None None 120404217 Common - Redoxin domain protein Mvan_3240 135 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 120401994 Common - O-methyltransferase domain protein Mvan_0979 34 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 120404744 Common - hypothetical protein Mvan_3785 2 None None None 120405155 Common - aminoglycoside phosphotransferase Mvan_4201 60 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 120404546 Common - leucyl aminopeptidase Mvan_3575 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 120404934 Common - virulence factor Mce family protein Mvan_3980 21 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120404690 Nonpathogen - hypothetical protein Mvan_3731 1 None None None 120406077 Common - phosphoribosylformylglycinamidine synthase subunit PurS Mvan_5129 95 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 120404362 Common - extracellular solute-binding protein, family 1 Mvan_3388 125 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 120401729 Common - alpha/beta hydrolase fold Mvan_0714 84 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120401824 Common - hypothetical protein Mvan_0809 3 None None None 120403862 Common - Alcohol dehydrogenase, zinc-binding domain protein Mvan_2879 200 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 120405661 Nonpathogen - integral membrane protein Mvan_4709 1 None None None 120403769 Common - malto-oligosyltrehalose synthase Mvan_2785 130 COG3280 TreY, Maltooligosyl trehalose synthase Carbohydrate transport and metabolism 120406250 Common - alpha/beta hydrolase fold Mvan_5302 77 COG2267 PldB, Lysophospholipase Lipid metabolism 120402616 Common - purine nucleoside phosphorylase Mvan_1610 133 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 120401822 Common - transcriptional regulator, XRE family Mvan_0807 30 COG1396 HipB, Predicted transcriptional regulators Transcription 120401457 Common - hypothetical protein Mvan_0432 8 None None None 120406135 Common - 6-phosphogluconate dehydrogenase, NAD-binding Mvan_5187 168 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 120403111 Common - LppZ Mvan_2119 29 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 120403542 Common - aldo/keto reductase Mvan_2555 200 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 120403469 Common - 3'-5' exonuclease Mvan_2479 108 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 120405854 Common - hypothetical protein Mvan_4904 2 None None None 120405911 Common - Rieske (2Fe-2S) domain protein Mvan_4962 82 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 120406672 Common - type I phosphodiesterase/nucleotide pyrophosphatase Mvan_5730 13 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 120405559 Common - 3-demethylubiquinone-9 3-methyltransferase Mvan_4607 65 COG3865 COG3865, Uncharacterized protein conserved in bacteria Function unknown 120406583 Common - acyl-CoA synthetase Mvan_5641 199 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120403263 Common - methionine aminopeptidase Mvan_2272 249 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 120401987 Common - transcriptional regulator, AraC family Mvan_0972 149 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 120403095 Common - hypothetical protein Mvan_2103 62 COG3176 COG3176, Putative hemolysin General function prediction only 120405944 Common - ABC-2 type transporter Mvan_4995 33 COG1511 COG1511, Predicted membrane protein Function unknown 120403988 Common - ABC transporter-related protein Mvan_3006 238 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 120406074 Nonpathogen - hypothetical protein Mvan_5126 2 None None None 120406893 Common - transposase, IS111A/IS1328/IS1533 Mvan_5958 40 None None None 120406866 Common - major facilitator superfamily MFS_1 Mvan_5926 18 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120404086 Common - O-methyltransferase domain protein Mvan_3107 32 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 120406144 Common - hypothetical protein Mvan_5196 3 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 120406194 Common - glycosyl transferase, group 1 Mvan_5246 182 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 120406406 Common - RDD domain containing protein Mvan_5459 29 COG1714 COG1714, Predicted membrane protein/domain Function unknown 120403744 Common - hypothetical protein Mvan_2760 1 None None None 120402328 Common - sulfatase Mvan_1317 76 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 120405513 Common - hypothetical protein Mvan_4561 6 None None None 120406611 Common - Rhodanese domain protein Mvan_5669 158 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 120406044 Common - GCN5-related N-acetyltransferase Mvan_5096 16 COG0456 RimI, Acetyltransferases General function prediction only 120401830 Common - Na+/solute symporter Mvan_0815 60 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 120401788 Common - hypothetical protein Mvan_0773 1 None None None 120405705 Common - hypothetical protein Mvan_4755 4 None None None 120405017 Common - HNH endonuclease Mvan_4063 94 COG1403 McrA, Restriction endonuclease Defense mechanisms 120406806 Common - cation diffusion facilitator family transporter Mvan_5864 207 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 120403323 Common - hypothetical protein Mvan_2332 9 COG4547 CobT, Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase) Coenzyme metabolism 120406332 Common - hypothetical protein Mvan_5384 2 None None None 120405231 Common - transcriptional regulator, TetR family Mvan_4277 3 COG1309 AcrR, Transcriptional regulator Transcription 120401816 Common - isocitrate lyase Mvan_0801 128 COG2224 AceA, Isocitrate lyase Energy production and conversion 120403997 Common - uncharacterized peroxidase-related enzyme Mvan_3017 48 COG2128 COG2128, Uncharacterized conserved protein Function unknown 120404045 Common - hypothetical protein Mvan_3066 2 None None None 120405435 Common - hypothetical protein Mvan_4483 5 None None None 120403837 Common - virulence factor Mce family protein Mvan_2853 6 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120405850 Common - hypothetical protein Mvan_4900 9 None None None 120404699 Common - Integrase, catalytic region Mvan_3740 145 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 120406123 Common - two component transcriptional regulator, winged helix family Mvan_5175 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 120403144 Common - uracil-DNA glycosylase Mvan_2152 129 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 120405165 Common - amidohydrolase 2 Mvan_4211 20 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 120405274 Common - hypothetical protein Mvan_4320 1 None None None 120404385 Common - ABC transporter-related protein Mvan_3412 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 120403602 Common - acetyl-CoA acetyltransferases Mvan_2617 184 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120406433 Common - hypothetical protein Mvan_5487 1 None None None 120402422 Common - phosphopantetheine-binding protein Mvan_1411 17 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120404601 Nonpathogen - hypothetical protein Mvan_3633 1 None None None 120402517 Common - RNA polymerase sigma factor SigD Mvan_1508 62 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 120403171 Common - nitrogen regulatory protein P-II Mvan_2179 180 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 120403949 Common - PE-PPE, C-terminal domain protein Mvan_2967 1 COG4547 CobT, Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase) Coenzyme metabolism 120404555 Common - RDD domain containing protein Mvan_3584 10 None None None 120401869 Common - hypothetical protein Mvan_0854 27 COG3662 COG3662, Uncharacterized protein conserved in bacteria Function unknown 120404401 Common - precorrin-3B synthase Mvan_3429 56 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 120401779 Common groEL chaperonin GroEL Mvan_0764 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 120406741 Common - ribonuclease Z Mvan_5799 122 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 120402033 Common - regulatory proteins, IclR Mvan_1018 119 COG1414 IclR, Transcriptional regulator Transcription 120406978 Common - ABC transporter-related protein Mvan_6048 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 120404612 Common - filamentation induced by cAMP protein Fic Mvan_3644 39 COG2184 Fic, Protein involved in cell division Cell division and chromosome partitioning 120404499 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase Mvan_3527 206 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 120403506 Nonpathogen - phage major capsid protein, HK97 Mvan_2518 2 COG4653 COG4653, Predicted phage phi-C31 gp36 major capsid-like protein General function prediction only 120406604 Common - prephenate dehydratase Mvan_5662 211 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 120401882 Common - cytochrome c biogenesis protein, transmembrane region Mvan_0867 96 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 120403406 Common - NADH ubiquinone oxidoreductase, 20 kDa subunit Mvan_2416 77 COG1740 HyaA, Ni,Fe-hydrogenase I small subunit Energy production and conversion 120406697 Common - hypothetical protein Mvan_5755 1 None None None 120404983 Common - DSBA oxidoreductase Mvan_4029 2 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 120403267 Common - asparagine synthase (glutamine-hydrolyzing) Mvan_2276 165 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 120404068 Common - 6-phosphogluconate dehydrogenase Mvan_3089 186 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 120402005 Nonpathogen - hypothetical protein Mvan_0990 2 None None None 120406780 Common - protein of unknown function DUF1212 Mvan_5838 23 COG2966 COG2966, Uncharacterized conserved protein Function unknown 120405679 Common - Male sterility C-terminal domain Mvan_4728 60 COG3320 COG3320, Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 120406621 Common - copper resistance protein CopC Mvan_5679 21 COG2372 CopC, Uncharacterized protein, homolog of Cu resistance protein CopC General function prediction only 120403121 Common - 3-isopropylmalate dehydrogenase Mvan_2129 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 120402288 Common - hypothetical protein Mvan_1277 3 None None None 120406518 Common - polar amino acid ABC transporter, inner membrane subunit Mvan_5576 190 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 120402338 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mvan_1327 175 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 120406163 Common - acyl-CoA synthetase Mvan_5215 219 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120401183 Common - regulatory proteins, IclR Mvan_0155 115 COG1414 IclR, Transcriptional regulator Transcription 120403762 Common - major facilitator superfamily MFS_1 Mvan_2778 62 None None None 120404165 Common - hypothetical protein Mvan_3186 3 None None None 120401377 Common - aldehyde dehydrogenase Mvan_0352 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 120401862 Common - delta-aminolevulinic acid dehydratase Mvan_0847 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 120402828 Common - Rhodanese domain protein Mvan_1829 156 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 120402002 Common - Alpha/beta hydrolase fold-3 domain protein Mvan_0987 103 COG0657 Aes, Esterase/lipase Lipid metabolism 120406179 Nonpathogen - hypothetical protein Mvan_5231 1 None None None 120404565 Common - hypothetical protein Mvan_3596 10 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 120406084 Common - hypothetical protein Mvan_5136 5 COG4270 COG4270, Predicted membrane protein Function unknown 120406964 Common rpsF 30S ribosomal protein S6 Mvan_6034 202 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 120404288 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein Mvan_3313 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 120404235 Nonpathogen - hypothetical protein Mvan_3259 1 None None None 120405937 Common - hypothetical protein Mvan_4988 6 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 120405102 Common - virulence factor Mce family protein Mvan_4148 6 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120404004 Common - putative agmatinase Mvan_3024 141 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 120404677 Nonpathogen - hypothetical protein Mvan_3715 1 None None None 120404723 Common - beta-lactamase Mvan_3764 52 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 120405680 Common - transcriptional regulator, TetR family Mvan_4729 112 COG1309 AcrR, Transcriptional regulator Transcription 120405715 Common - AMP-dependent synthetase and ligase Mvan_4765 219 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 120404544 Common - branched-chain amino acid aminotransferase Mvan_3573 201 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 120405148 Common - transcriptional regulator, TetR family Mvan_4194 145 COG1309 AcrR, Transcriptional regulator Transcription 120404702 Nonpathogen - hypothetical protein Mvan_3743 1 None None None 120407006 Common - ribonuclease P protein component Mvan_6077 29 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 120405128 Common - 6-phosphogluconate dehydrogenase, NAD-binding Mvan_4174 139 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 120401156 Common - MscS Mechanosensitive ion channel Mvan_0128 90 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 120406899 Nonpathogen - hypothetical protein Mvan_5964 2 None None None 120401289 Common - two component transcriptional regulator, LuxR family Mvan_0263 178 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 120404774 Common - protein of unknown function DUF477 Mvan_3816 10 COG4907 COG4907, Predicted membrane protein Function unknown 120401438 Common - cell divisionFtsK/SpoIIIE Mvan_0413 182 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 120404337 Common - hypothetical protein Mvan_3363 30 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120405998 Common - FHA domain containing protein Mvan_5049 12 COG4982 COG4982, 3-oxoacyl- acyl-carrier protein 120402495 Common - protein of unknown function UPF0079 Mvan_1486 78 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 120402351 Common - ribosomal protein L30 Mvan_1340 95 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 120402208 Common - Chalcone and stilbene synthases domain protein Mvan_1196 45 COG3424 BcsA, Predicted naringenin-chalcone synthase Secondary metabolites biosynthesis, transport, and catabolism 120406248 Common - major facilitator superfamily MFS_1 Mvan_5300 157 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 120406890 Nonpathogen - hypothetical protein Mvan_5954 4 None None None 120403243 Common - protein of unknown function DUF427 Mvan_2252 41 COG2343 COG2343, Uncharacterized protein conserved in bacteria Function unknown 120404635 Common - hypothetical protein Mvan_3671 12 COG3462 COG3462, Predicted membrane protein Function unknown 120403746 Common - methylmalonyl-CoA mutase, beta subunit Mvan_2762 105 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 120401922 Common - hypothetical protein Mvan_0907 9 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 120405062 Common - putative glutamate synthase (NADPH) small subunit Mvan_4108 218 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 120402852 Common - purine catabolism PurC domain protein Mvan_1854 27 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 120405691 Common - hypothetical protein Mvan_4740 1 None None None 120403074 Common - Cytochrome-c oxidase Mvan_2082 171 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 120405347 Common - virulence factor Mce family protein Mvan_4394 13 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120402890 Common - acyl-CoA dehydrogenase domain protein Mvan_1892 159 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120401639 Common - hypothetical protein Mvan_0623 1 None None None 120402974 Common - transcriptional regulator, GntR family Mvan_1978 135 COG1802 GntR, Transcriptional regulators Transcription 120404576 Common - hypothetical protein Mvan_3607 1 None None None 120402025 Common - PKD domain containing protein Mvan_1010 116 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 120405502 Common pimE mannosyltransferase Mvan_4550 13 None None None 120405390 Common - putative phosphohistidine phosphatase, SixA Mvan_4437 66 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 120405369 Common - Benzene 1,2-dioxygenase Mvan_4416 26 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 120403417 Common - extracellular solute-binding protein, family 3 Mvan_2427 173 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 120404728 Common - hypothetical protein Mvan_3769 1 None None None 120405362 Common - monooxygenase, FAD-binding Mvan_4409 78 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 120402055 Common - putative cold-shock DNA-binding domain protein Mvan_1040 180 COG1278 CspC, Cold shock proteins Transcription 120403225 Common - cytochrome P450 Mvan_2234 68 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120402201 Common - hypothetical protein Mvan_1189 8 None None None 120402101 Common - DNA mismatch endonuclease vsr Mvan_1087 66 COG3727 Vsr, DNA G:T-mismatch repair endonuclease DNA replication, recombination, and repair 120405340 Common - hypothetical protein Mvan_4387 2 COG3595 COG3595, Uncharacterized conserved protein Function unknown 120406492 Common ligC ATP-dependent DNA ligase Mvan_5549 75 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 120401842 Common - glycosyl transferase, group 1 Mvan_0827 160 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 120402907 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mvan_1910 141 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 120406771 Common - transcriptional regulator, AraC family Mvan_5829 129 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 120405847 Common - putative acetone carboxylase gamma subunit Mvan_4897 14 COG4647 AcxC, Acetone carboxylase, gamma subunit Secondary metabolites biosynthesis, transport, and catabolism 120406312 Common panC pantoate--beta-alanine ligase Mvan_5364 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 120403613 Common - transglutaminase, N-terminal domain protein Mvan_2628 84 COG4196 COG4196, Uncharacterized protein conserved in bacteria Function unknown 120402614 Common - transcriptional regulator, MarR family Mvan_1608 48 COG1846 MarR, Transcriptional regulators Transcription 120404759 Nonpathogen - hypothetical protein Mvan_3801 3 COG2253 COG2253, Uncharacterized conserved protein Function unknown 120405834 Common - membrane protein of unknown function Mvan_4884 34 COG1950 COG1950, Predicted membrane protein Function unknown 120406699 Common - beta-lactamase Mvan_5757 109 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 120402357 Common - putative methyltransferase Mvan_1346 19 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 120402594 Common - putative succinate dehydrogenase Mvan_1588 13 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 120403325 Nonpathogen - hypothetical protein Mvan_2334 1 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 120404842 Common - binding-protein-dependent transport systems inner membrane component Mvan_3885 103 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 120403220 Common - L-carnitine dehydratase/bile acid-inducible protein F Mvan_2229 115 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 120405480 Common - N-succinyldiaminopimelate aminotransferase Mvan_4528 227 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 120402453 Common - protein of unknown function DUF6, transmembrane Mvan_1442 91 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 120406823 Common - transcriptional regulator, TetR family Mvan_5881 16 COG1309 AcrR, Transcriptional regulator Transcription 120406651 Common - methionine sulfoxide reductase A Mvan_5709 204 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 120402384 Common - hypothetical protein Mvan_1373 5 None None None 120405094 Common - transcriptional regulator, TetR family Mvan_4140 32 COG1309 AcrR, Transcriptional regulator Transcription 120403011 Common - protein of unknown function DUF1486 Mvan_2017 1 None None None 120405610 Common - pantothenate kinase Mvan_4658 80 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 120402128 Common - phage integrase family protein Mvan_1114 200 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 120402697 Common - Integrase, catalytic region Mvan_1692 145 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 120405473 Common - hypothetical protein Mvan_4521 17 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 120402869 Common - enoyl-CoA hydratase Mvan_1871 181 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120406500 Common - DSBA oxidoreductase Mvan_5558 90 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 120406358 Common - heavy metal translocating P-type ATPase Mvan_5411 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 120402567 Common - tryptophanyl-tRNA synthetase Mvan_1560 234 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 120405674 Common - PE-PPE, C-terminal domain protein Mvan_4723 1 None None None 120401942 Common - virulence factor Mce family protein Mvan_0927 21 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120401885 Common - hypothetical protein Mvan_0870 32 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 120403454 Common - hypothetical protein Mvan_2464 4 None None None 120406794 Common - hypothetical protein Mvan_5852 7 COG3462 COG3462, Predicted membrane protein Function unknown 120401135 Common - Alcohol dehydrogenase, zinc-binding domain protein Mvan_0107 135 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 120402045 Common - 5-dehydro-4-deoxyglucarate dehydratase Mvan_1030 215 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 120403032 Common - transcriptional regulator, TetR family Mvan_2038 12 COG1309 AcrR, Transcriptional regulator Transcription 120405292 Common - modification methylase, HemK family Mvan_4338 214 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 120402476 Common - lysophospholipase-like protein Mvan_1467 9 COG2267 PldB, Lysophospholipase Lipid metabolism 120406752 Common - thioesterase superfamily protein Mvan_5810 54 COG0824 FcbC, Predicted thioesterase General function prediction only 120403005 Common - isochorismatase hydrolase Mvan_2011 58 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 120406146 Common - virulence factor Mce family protein Mvan_5198 6 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120404894 Common nadE NAD synthetase Mvan_3940 176 COG0171 NadE, NAD synthase Coenzyme metabolism 120402430 Common - zinc/iron permease Mvan_1419 41 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 120404296 Common - hypothetical protein Mvan_3322 17 COG3662 COG3662, Uncharacterized protein conserved in bacteria Function unknown 120401326 Common - cobalamin (vitamin B12) biosynthesis CbiX protein Mvan_0300 38 COG2138 COG2138, Uncharacterized conserved protein Function unknown 120401558 Common - transcriptional regulator, MarR family Mvan_0537 105 COG1846 MarR, Transcriptional regulators Transcription 120404413 Common - Sec-independent protein translocase, TatC subunit Mvan_3441 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 120402690 Common - Alcohol dehydrogenase, zinc-binding domain protein Mvan_1685 153 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 120402782 Common - diacylglycerol kinase, catalytic region Mvan_1783 27 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 120401722 Common thiE thiamine-phosphate pyrophosphorylase Mvan_0707 157 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 120402232 Common - GCN5-related N-acetyltransferase Mvan_1220 47 COG2144 COG2144, Selenophosphate synthetase-related proteins General function prediction only 120402326 Common - transcriptional regulator, TetR family Mvan_1315 33 COG1309 AcrR, Transcriptional regulator Transcription 120403580 Common - inner-membrane translocator Mvan_2595 163 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 120402176 Common - Integral membrane protein TerC Mvan_1164 89 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 120406912 Common - CHAP domain containing protein Mvan_5979 5 COG3942 COG3942, Surface antigen General function prediction only 120406396 Common - regulatory protein, LuxR Mvan_5449 44 COG3899 COG3899, Predicted ATPase General function prediction only 120402629 Nonpathogen - hypothetical protein Mvan_1623 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 120402272 Common - endonuclease IV Mvan_1261 106 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 120401352 Common - glucose-methanol-choline oxidoreductase Mvan_0327 93 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 120402196 Common - Amidohydrolase 3 Mvan_1184 109 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 120403372 Common - Dihydrofolate reductase Mvan_2381 143 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 120402559 Common - Methyltransferase type 11 Mvan_1552 158 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 120406645 Common - FAD dependent oxidoreductase Mvan_5703 92 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 120401503 Common - DNA replication protein-like Mvan_0481 40 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 120404652 Common - hypothetical protein Mvan_3689 11 None None None 120402658 Common - L-lysine aminotransferase Mvan_1652 236 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 120402927 Common - hypothetical protein Mvan_1930 7 None None None 120404669 Common - peptidase M48, Ste24p Mvan_3707 15 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 120405568 Nonpathogen - hypothetical protein Mvan_4616 1 None None None 120401167 Common - virulence factor Mce family protein Mvan_0139 21 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120401700 Common - ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp Mvan_0685 204 COG0027 PurT, Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Nucleotide transport and metabolism 120402074 Common - transcriptional regulator, TetR family Mvan_1059 67 COG1309 AcrR, Transcriptional regulator Transcription 120403674 Common - riboflavin biosynthesis protein RibD Mvan_2690 224 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 120402766 Common - ferredoxin Mvan_1767 124 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 120403690 Common secG preprotein translocase subunit SecG Mvan_2706 2 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 120403186 Common rnhB ribonuclease HII Mvan_2194 212 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 120406265 Common - periplasmic binding protein/LacI transcriptional regulator Mvan_5317 124 COG1609 PurR, Transcriptional regulators Transcription 120401577 Common - dihydrodipicolinate synthetase Mvan_0558 117 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 120406889 Nonpathogen - hypothetical protein Mvan_5953 21 COG0433 COG0433, Predicted ATPase General function prediction only 120401906 Common - putative conserved integral membrane protein Mvan_0891 5 COG5305 COG5305, Predicted membrane protein Function unknown 120405121 Common - hypothetical protein Mvan_4167 10 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120405136 Common - Taurine catabolism dioxygenase TauD/TfdA Mvan_4182 47 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 120403520 Nonpathogen - hypothetical protein Mvan_2532 1 None None None 120401038 Common - two component transcriptional regulator, LuxR family Mvan_0010 191 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 120406381 Common - hypothetical protein Mvan_5434 1 None None None 120403903 Common - glutamine synthetase, catalytic region Mvan_2920 222 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 120403675 Common - major facilitator superfamily MFS_1 Mvan_2691 195 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120403522 Nonpathogen - hypothetical protein Mvan_2534 1 None None None 120401792 Common - transcriptional regulator, TrmB Mvan_0777 11 COG1510 COG1510, Predicted transcriptional regulators Transcription 120402677 Nonpathogen - hypothetical protein Mvan_1671 1 None None None 120403603 Common - transcriptional regulator, HxlR family Mvan_2618 82 COG1733 COG1733, Predicted transcriptional regulators Transcription 120402816 Common - heat shock protein 90 Mvan_1817 150 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 120403691 Common - phosphoenolpyruvate carboxylase Mvan_2707 119 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 120406291 Common - protein of unknown function DUF147 Mvan_5343 28 COG1623 COG1623, Predicted nucleic-acid-binding protein (contains the HHH domain) General function prediction only 120402088 Common - hypothetical protein Mvan_1073 20 None None None 120406238 Common - aspartate aminotransferase Mvan_5290 236 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 120402258 Common - hypothetical protein Mvan_1246 6 None None None 120402689 Common - glycosyl transferase, group 1 Mvan_1684 73 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 120402670 Common - Carbamoyl-phosphate synthase L chain, ATP-binding Mvan_1664 239 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 120406082 Common - glutathione peroxidase Mvan_5134 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 120404067 Common - peptidase M48, Ste24p Mvan_3088 14 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 120401046 Common - hypothetical protein Mvan_0018 6 None None None 120404399 Common - putative monooxygenase Mvan_3427 77 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 120402151 Common - plasmid pRiA4b ORF-3 family protein Mvan_1138 36 None None None 120406079 Common - beta-lactamase domain protein Mvan_5131 17 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 120403779 Common - putative transmembrane protein Mvan_2795 1 None None None 120404441 Common - 17 kDa surface antigen Mvan_3469 8 COG3918 COG3918, Predicted membrane protein Function unknown 120401603 Nonpathogen - hypothetical protein Mvan_0587 3 COG1102 Cmk, Cytidylate kinase Nucleotide transport and metabolism 120401855 Common - NAD-dependent epimerase/dehydratase Mvan_0840 65 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 120405306 Nonpathogen - hypothetical protein Mvan_4352 1 None None None 120406173 Common - Rieske (2Fe-2S) domain protein Mvan_5225 69 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 120402599 Common - hypothetical protein Mvan_1593 5 None None None 120403029 Common - hypothetical protein Mvan_2035 36 COG4637 COG4637, Predicted ATPase General function prediction only 120406233 Common - acyl-CoA dehydrogenase domain protein Mvan_5285 147 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120401548 Common - Alcohol dehydrogenase, zinc-binding domain protein Mvan_0527 208 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 120401797 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Mvan_0782 145 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 120403887 Common - phosphonate ABC transporter, periplasmic phosphonate-binding protein Mvan_2904 92 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 120404022 Common - bacterioferritin Mvan_3043 106 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 120403211 Common - uridylate kinase Mvan_2220 241 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 120403578 Common - ABC transporter-related protein Mvan_2593 249 COG4674 COG4674, Uncharacterized ABC-type transport system, ATPase component General function prediction only 120403912 Common - hypothetical protein Mvan_2929 2 None None None 120402870 Common - NADH dehydrogenase subunit N Mvan_1872 208 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 120404388 Common - transcriptional regulator, CadC Mvan_3415 170 COG3710 CadC, DNA-binding winged-HTH domains Transcription 120405522 Common - NAD-dependent deacetylase Mvan_4570 152 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 120406766 Common - hypothetical protein Mvan_5824 7 None None None 120402536 Common - short chain dehydrogenase Mvan_1527 217 COG3320 COG3320, Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 120403712 Nonpathogen - hypothetical protein Mvan_2728 1 None None None 120405978 Common - hypothetical protein Mvan_5029 22 None None None 120404456 Common - hypothetical protein Mvan_3484 3 None None None 120403981 Common - competence damage-inducible protein A Mvan_2999 212 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 120406935 Nonpathogen - hypothetical protein Mvan_6003 3 None None None 120401927 Common - Transketolase, central region Mvan_0912 221 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 120406725 Common - MOSC domain containing protein Mvan_5783 79 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 120404311 Common - Mycobacterium 19 kDa lipoprotein antigen family protein Mvan_3337 3 None None None 120404790 Common - PhoH family protein Mvan_3832 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 120401314 Common - hypothetical protein Mvan_0288 3 None None None 120402922 Common - luciferase family protein Mvan_1925 128 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120404733 Common - binding-protein-dependent transport systems inner membrane component Mvan_3774 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 120406463 Common - domain of unknown function DUF1727 Mvan_5520 43 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 120404304 Common lysS lysyl-tRNA synthetase Mvan_3330 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 120404321 Common - transcriptional regulator, TetR family Mvan_3347 24 COG1309 AcrR, Transcriptional regulator Transcription 120401608 Common - alpha/beta hydrolase fold Mvan_0592 173 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120401213 Common - putative conserved transmembrane protein Mvan_0186 1 None None None 120403308 Common - MATE efflux family protein Mvan_2317 154 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 120402305 Common - transcriptional regulator, TetR family Mvan_1294 9 COG1309 AcrR, Transcriptional regulator Transcription 120403428 Common - molybdopterin guanine dinucleotide-containing S/N-oxide reductases Mvan_2438 162 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 120406498 Common - transcriptional repressor, CopY family Mvan_5556 38 COG3682 COG3682, Predicted transcriptional regulator Transcription 120401315 Common - hypothetical protein Mvan_0289 66 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 120403498 Nonpathogen - hypothetical protein Mvan_2510 1 None None None 120404174 Nonpathogen - hypothetical protein Mvan_3195 1 None None None 120402411 Common - hypothetical protein Mvan_1400 4 None None None 120403561 Common ruvB Holliday junction DNA helicase B Mvan_2575 216 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 120402437 Common - MgtE integral membrane region Mvan_1426 147 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 120406285 Common - RNA methyltransferase, TrmH family, group 3 Mvan_5337 213 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 120401693 Common - thioesterase superfamily protein Mvan_0678 9 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 120405283 Common - F0F1 ATP synthase subunit gamma Mvan_4329 207 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 120405227 Common - cyclase/dehydrase Mvan_4273 1 None None None 120406298 Nonpathogen - hypothetical protein Mvan_5350 1 None None None 120403360 Common - Rieske (2Fe-2S) domain protein Mvan_2369 100 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 120402315 Common - ribosomal protein S10 Mvan_1304 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 120404012 Nonpathogen - hypothetical protein Mvan_3032 1 None None None 120403753 Common ileS isoleucyl-tRNA synthetase Mvan_2769 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 120402138 Nonpathogen - hypothetical protein Mvan_1125 1 None None None 120403359 Common - hypothetical protein Mvan_2368 15 None None None 120403701 Common - OpcA protein Mvan_2717 20 COG3429 COG3429, Glucose-6-P dehydrogenase subunit Carbohydrate transport and metabolism 120405586 Common - exodeoxyribonuclease VII, small subunit Mvan_4634 54 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 120402781 Common - transcription factor WhiB Mvan_1782 19 None None None 120402796 Common - molybdopterin biosynthesis-like protein MoeZ Mvan_1797 229 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 120406971 Common - hypothetical protein Mvan_6041 20 COG4552 Eis, Predicted acetyltransferase involved in intracellular survival and related acetyltransferases General function prediction only 120401891 Common - hypothetical protein Mvan_0876 2 None None None 120406227 Common - amidohydrolase Mvan_5279 149 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 120401088 Common - hypothetical protein Mvan_0060 12 None None None 120402405 Common - PfkB domain protein Mvan_1394 95 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 120401341 Common - uncharacterized domain 1 Mvan_0316 41 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 120404687 Common - regulatory protein, ArsR Mvan_3727 157 COG0640 ArsR, Predicted transcriptional regulators Transcription 120405554 Common - virulence factor Mce family protein Mvan_4602 36 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120403025 Common - cytochrome P450 Mvan_2031 92 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120403093 Common - dTDP-4-dehydrorhamnose reductase Mvan_2101 87 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 120403391 Common - Limonene-1,2-epoxide hydrolase Mvan_2400 4 COG4308 LimA, Limonene-1,2-epoxide hydrolase Secondary metabolites biosynthesis, transport, and catabolism 120403020 Common - oxidoreductase, molybdopterin binding Mvan_2026 121 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 120402342 Common - Endoribonuclease L-PSP Mvan_1331 4 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 120404316 Common - UspA domain protein Mvan_3342 89 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 120404792 Common - hypothetical protein Mvan_3834 1 None None None 120406347 Common - DEAD/DEAH box helicase domain protein Mvan_5399 89 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 120406256 Common - Acyl-CoA dehydrogenase, type 2, C-terminal domain Mvan_5308 67 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120403933 Common - peptidylprolyl isomerase, FKBP-type Mvan_2950 106 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 120404001 Common - FHA domain containing protein Mvan_3021 1 COG3456 COG3456, Uncharacterized conserved protein, contains FHA domain Signal transduction mechanisms 120406095 Common - amino acid permease-associated region Mvan_5147 130 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 120404843 Common - NLPA lipoprotein Mvan_3886 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 120402607 Common - hypothetical protein Mvan_1601 41 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120405086 Common - hypothetical protein Mvan_4132 5 None None None 120404864 Common - protein of unknown function DUF403 Mvan_3910 83 COG2307 COG2307, Uncharacterized protein conserved in bacteria Function unknown 120405030 Common - protein of unknown function UPF0089 Mvan_4076 28 None None None 120401142 Common - putative transcriptional regulator, MerR family Mvan_0114 19 COG0789 SoxR, Predicted transcriptional regulators Transcription 120406541 Common - binding-protein-dependent transport systems inner membrane component Mvan_5599 128 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 120405814 Common - luciferase family protein Mvan_4864 98 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120402229 Common - Mg2+ transporter protein, CorA family protein Mvan_1217 115 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 120406478 Common - putative transcriptional regulator, GntR family Mvan_5535 25 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 120404511 Common - protein kinase Mvan_3539 151 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 120404326 Common - hypothetical protein Mvan_3352 1 None None None 120404203 Common - cation diffusion facilitator family transporter Mvan_3225 208 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 120405654 Common - anti-sigma-factor antagonist Mvan_4702 8 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 120402809 Common - ABC-1 domain protein Mvan_1810 184 COG0661 AarF, Predicted unusual protein kinase General function prediction only 120403381 Common - putative methyltransferase Mvan_2390 32 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 120403827 Common - inner-membrane translocator Mvan_2843 152 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 120406448 Common - nitroreductase Mvan_5505 35 COG0778 NfnB, Nitroreductase Energy production and conversion 120404878 Common - Phosphoglycerate mutase Mvan_3924 166 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 120403314 Nonpathogen - transcriptional regulator, TetR family Mvan_2323 4 COG1309 AcrR, Transcriptional regulator Transcription 120406873 Common - Tn554-related, transposase C Mvan_5933 8 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 120401322 Common - heat shock protein Hsp20 Mvan_0296 70 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 120401737 Common - hypothetical protein Mvan_0722 7 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 120402952 Common - hypothetical protein Mvan_1956 20 None None None 120403973 Common - hypothetical protein Mvan_2991 3 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 120402580 Common - UspA domain protein Mvan_1573 11 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 120405804 Common - putative magnesium chelatase Mvan_4854 59 COG1239 ChlI, Mg-chelatase subunit ChlI Coenzyme metabolism 120404098 Common - acyltransferase PapA5 Mvan_3119 3 COG4908 COG4908, Uncharacterized protein containing a NRPS condensation (elongation) domain General function prediction only 120405865 Common - ATP-dependent DNA ligase Mvan_4915 110 COG3285 COG3285, Predicted eukaryotic-type DNA primase DNA replication, recombination, and repair 120405797 Common - acyl-CoA dehydrogenase domain protein Mvan_4847 157 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120405327 Nonpathogen - hypothetical protein Mvan_4374 2 None None None 120405045 Common - Propionyl-CoA carboxylase Mvan_4091 143 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 120401772 Common - luciferase family protein Mvan_0757 64 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120405458 Common - DNA-3-methyladenine glycosylase I Mvan_4506 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 120403947 Common - protein of unknown function DUF218 Mvan_2964 49 COG1434 COG1434, Uncharacterized conserved protein Function unknown 120406305 Common - transposase, IS4 family protein Mvan_5357 25 COG5421 COG5421, Transposase DNA replication, recombination, and repair 120403795 Common - Phosphoribosyl-AMP cyclohydrolase Mvan_2811 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 120402515 Common - transcription factor WhiB Mvan_1506 16 None None None 120403817 Common - polar amino acid ABC transporter, inner membrane subunit Mvan_2833 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 120405920 Common - short-chain dehydrogenase/reductase SDR Mvan_4971 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120401129 Nonpathogen - hypothetical protein Mvan_0101 2 None None None 120405078 Common acpS 4'-phosphopantetheinyl transferase Mvan_4124 10 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 120404431 Common - low molecular weight antigen CFP2 (low molecular weight protein antigen 2) (CFP-2) Mvan_3459 1 None None None 120404465 Nonpathogen - hypothetical protein Mvan_3493 6 None None None 120402067 Common - glycosyl transferase, group 1 Mvan_1052 69 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 120402546 Common - protein of unknown function DUF742 Mvan_1538 9 None None None 120404518 Common - Arsenite-transporting ATPase Mvan_3546 82 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 120406506 Common - amino acid permease-associated region Mvan_5564 124 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 120405003 Common - hypothetical protein Mvan_4049 4 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 120404645 Common - heavy metal translocating P-type ATPase Mvan_3681 231 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 120404574 Common - CHAD domain containing protein Mvan_3605 33 COG5607 COG5607, Uncharacterized conserved protein Function unknown 120406523 Common - hypothetical protein Mvan_5581 1 None None None 120401469 Common - protein of unknown function UPF0089 Mvan_0444 28 None None None 120406507 Common - aminotransferase class-III Mvan_5565 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 120404134 Common - Amidase Mvan_3155 214 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 120404568 Common - TAP domain protein Mvan_3599 39 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120402214 Common - glycine cleavage T protein (aminomethyl transferase) Mvan_1202 180 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 120403820 Common - two component transcriptional regulator, LuxR family Mvan_2836 203 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 120401967 Common - GntR domain protein Mvan_0952 140 COG2186 FadR, Transcriptional regulators Transcription 120403230 Common - cytochrome P450 Mvan_2239 74 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120403199 Common - peptidase M23B Mvan_2208 55 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 120402571 Common - AMP-dependent synthetase and ligase Mvan_1564 220 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 120404975 Common - thioredoxin Mvan_4021 230 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 120405154 Common - acyl-CoA dehydrogenase domain protein Mvan_4200 159 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120401224 Common - hypothetical protein Mvan_0197 6 None None None 120406197 Common - O-antigen polymerase Mvan_5249 6 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 120405397 Common - protein of unknown function DUF124 Mvan_4445 25 COG2013 COG2013, Uncharacterized conserved protein Function unknown 120406024 Common - FAD dependent oxidoreductase Mvan_5076 87 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 120402773 Common - Methyltransferase type 11 Mvan_1774 37 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 120406668 Common - hypothetical protein Mvan_5726 10 None None None 120402187 Common - alpha/beta hydrolase fold Mvan_1175 6 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120402222 Common - exodeoxyribonuclease V, gamma subunit Mvan_1210 65 COG1330 RecC, Exonuclease V gamma subunit DNA replication, recombination, and repair 120403444 Common - ribonuclease BN Mvan_2454 45 COG1295 Rbn, Predicted membrane protein Function unknown 120404358 Common - peptidase S58, DmpA Mvan_3384 53 COG3191 DmpA, L-aminopeptidase/D-esterase Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120403566 Common - 4-aminobutyrate aminotransferase Mvan_2581 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 120401442 Common - hypothetical protein Mvan_0417 1 None None None 120405468 Common - aminotransferase, class IV Mvan_4516 177 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 120401366 Common - acyl-CoA dehydrogenase domain protein Mvan_0341 157 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120401802 Common - hypothetical protein Mvan_0787 69 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 120404812 Common - hypothetical protein Mvan_3854 13 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120406957 Nonpathogen - hypothetical protein Mvan_6026 3 None None None 120401268 Common - glycosyl transferase, group 1 Mvan_0242 204 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 120405060 Common - phosphoenolpyruvate synthase Mvan_4106 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 120401495 Nonpathogen - hypothetical protein Mvan_0471 1 COG3255 COG3255, Putative sterol carrier protein Lipid metabolism 120401970 Common - transcriptional regulator, TetR family Mvan_0955 104 COG1309 AcrR, Transcriptional regulator Transcription 120403656 Common - Alpha/beta hydrolase fold-3 domain protein Mvan_2672 138 COG0657 Aes, Esterase/lipase Lipid metabolism 120401302 Common - PE-PPE, C-terminal domain protein Mvan_0276 1 None None None 120405628 Common - lipolytic enzyme, G-D-S-L family Mvan_4676 14 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 120403416 Common - polar amino acid ABC transporter, inner membrane subunit Mvan_2426 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 120403192 Common - protein of unknown function DUF1206 Mvan_2200 10 None None None 120402744 Common - Rubredoxin-type Fe(Cys)4 protein Mvan_1744 111 COG1773 COG1773, Rubredoxin Energy production and conversion 120406317 Common - dihydroneopterin aldolase Mvan_5369 61 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 120406322 Common - transcriptional regulator, TetR family Mvan_5374 1 COG1309 AcrR, Transcriptional regulator Transcription 120406535 Common - diguanylate cyclase with PAS/PAC sensor Mvan_5593 189 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 120403059 Common - transposase, mutator type Mvan_2066 82 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 120405073 Common - hypothetical protein Mvan_4119 2 None None None 120404371 Common - hypothetical protein Mvan_3398 12 None None None 120402759 Common - hypothetical protein Mvan_1760 12 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 120405894 Nonpathogen - hypothetical protein Mvan_4945 1 None None None 120401658 Common - hypothetical protein Mvan_0642 3 None None None 120403647 Common - carbamoyl phosphate synthase small subunit Mvan_2663 232 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 120405789 Common - hypothetical protein Mvan_4839 2 None None None 120402241 Common rpmG 50S ribosomal protein L33 Mvan_1229 83 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 120403298 Common - major facilitator superfamily MFS_1 Mvan_2307 154 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120406408 Common - transcriptional regulator, PadR-like family Mvan_5461 29 COG1695 COG1695, Predicted transcriptional regulators Transcription 120403349 Common - hydrogenase expression/synthesis, HypA Mvan_2358 34 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 120404102 Common - beta-ketoacyl synthase Mvan_3123 210 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 120406615 Common - hypothetical protein Mvan_5673 7 None None None 120401534 Common - phage integrase family protein Mvan_0512 80 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 120402254 Nonpathogen - hypothetical protein Mvan_1242 1 None None None 120402488 Common - hypothetical protein Mvan_1479 6 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 120402425 Common - hypothetical protein Mvan_1414 7 None None None 120403270 Common - peptidase C26 Mvan_2279 118 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 120406018 Common - aminotransferase Mvan_5070 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 120405641 Common - hypothetical protein Mvan_4689 1 None None None 120406900 Common - Integrase, catalytic region Mvan_5965 50 None None None 120402733 Common - LPPG Mvan_1733 39 COG0391 COG0391, Uncharacterized conserved protein Function unknown 120402901 Common - adenylyl cyclase class-3/4/guanylyl cyclase Mvan_1904 96 COG3899 COG3899, Predicted ATPase General function prediction only 120403804 Common - TM2 domain containing protein+B7201 Mvan_2820 7 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 120402443 Common rpmJ 50S ribosomal protein L36 Mvan_1432 132 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 120402378 Common - hypothetical protein Mvan_1367 12 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120405598 Common - hypothetical protein Mvan_4646 8 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 120404247 Common - protein of unknown function DUF81 Mvan_3272 60 COG0730 COG0730, Predicted permeases General function prediction only 120406681 Common - ABC transporter-related protein Mvan_5739 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 120403009 Common - transcriptional regulator, TetR family Mvan_2015 7 COG1309 AcrR, Transcriptional regulator Transcription 120401996 Nonpathogen - hypothetical protein Mvan_0981 1 None None None 120404786 Common era GTP-binding protein Era Mvan_3828 223 COG1159 Era, GTPase General function prediction only 120406361 Nonpathogen - hypothetical protein Mvan_5414 2 COG4454 COG4454, Uncharacterized copper-binding protein Inorganic ion transport and metabolism 120403995 Common - hypothetical protein Mvan_3013 1 None None None 120406281 Common rpmE2 50S ribosomal protein L31 type B Mvan_5333 161 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 120406390 Common - metallophosphoesterase Mvan_5443 71 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 120402860 Common - alpha/beta hydrolase fold Mvan_1862 108 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120401656 Common - hypothetical protein Mvan_0640 5 None None None 120403234 Common - cyclohexanone monooxygenase Mvan_2243 62 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 120402031 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Mvan_1016 225 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 120402986 Common - enoyl-CoA hydratase Mvan_1990 178 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120401848 Common - Ppx/GppA phosphatase Mvan_0833 180 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 120404936 Common - virulence factor Mce family protein Mvan_3982 8 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120403109 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B Mvan_2117 212 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 120404738 Common - hypothetical protein Mvan_3779 32 None None None 120401370 Common - Carbamoyl-phosphate synthase L chain, ATP-binding Mvan_0345 226 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 120405252 Common - DEAD/DEAH box helicase domain protein Mvan_4298 127 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 120404768 Common - ATPase, P-type (transporting), HAD superfamily, subfamily IC Mvan_3810 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 120401860 Common hemC porphobilinogen deaminase Mvan_0845 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 120402180 Common - luciferase family protein Mvan_1168 27 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120402585 Common - Phytoene dehydrogenase-related protein Mvan_1578 84 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 120406397 Common - Alcohol dehydrogenase, zinc-binding domain protein Mvan_5450 212 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 120402330 Common - protein of unknown function DUF323 Mvan_1319 92 COG1262 COG1262, Uncharacterized conserved protein Function unknown 120401081 Common - Haloacid dehalogenase domain protein hydrolase Mvan_0053 64 COG0546 Gph, Predicted phosphatases General function prediction only 120405314 Common - Phage-related minor tail protein-like Mvan_4360 10 COG5280 COG5280, Phage-related minor tail protein Function unknown 120404653 Common - DSBA oxidoreductase Mvan_3690 73 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 120406686 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Mvan_5744 164 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 120402293 Common - elongation factor Tu Mvan_1282 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 120402765 Common - hypothetical protein Mvan_1766 10 None None None 120406886 Common - cell divisionFtsK/SpoIIIE Mvan_5950 159 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 120405109 Common - L-carnitine dehydratase/bile acid-inducible protein F Mvan_4155 112 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 120403851 Common - 3-ketosteroid-delta-1-dehydrogenase Mvan_2868 61 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 120404282 Common - argininosuccinate lyase Mvan_3307 216 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 120405442 Common - Lytic transglycosylase, catalytic Mvan_4490 20 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 120403256 Common - transposase IS116/IS110/IS902 family protein Mvan_2265 30 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 120404363 Common - binding-protein-dependent transport systems inner membrane component Mvan_3389 187 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 120401562 Common - oxidoreductase domain protein Mvan_0541 178 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 120403896 Common - hypothetical protein Mvan_2913 1 None None None 120402110 Common - helicase domain protein Mvan_1096 168 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 120401663 Common - Nitrile hydratase Mvan_0647 19 None None None 120403755 Common - DNA polymerase IV Mvan_2771 184 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 120405451 Common - ABC transporter-related protein Mvan_4499 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 120402848 Common - Glutamate--ammonia ligase Mvan_1850 220 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 120403164 Common - formamidopyrimidine-DNA glycosylase Mvan_2172 180 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 120404536 Common - asparagine synthase (glutamine-hydrolyzing) Mvan_3565 150 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 120405342 Common - 2-nitropropane dioxygenase, NPD Mvan_4389 67 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 120404418 Nonpathogen - hypothetical protein Mvan_3446 1 None None None 120404515 Common - putative conserved integral membrane protein Mvan_3543 12 COG5650 COG5650, Predicted integral membrane protein Function unknown 120402468 Nonpathogen - hypothetical protein Mvan_1458 1 None None None 120406235 Common - acyl-CoA dehydrogenase domain protein Mvan_5287 148 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120404269 Common - tyrosyl-tRNA synthetase Mvan_3294 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 120401097 Common - hypothetical protein Mvan_0069 12 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 120401573 Common - putative transposase Mvan_0552 5 None None None 120402700 Nonpathogen - hypothetical protein Mvan_1697 1 None None None 120405205 Common - short-chain dehydrogenase/reductase SDR Mvan_4251 230 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120404966 Common - Xylose isomerase domain protein TIM barrel Mvan_4012 82 COG3622 Hfi, Hydroxypyruvate isomerase Carbohydrate transport and metabolism 120405309 Nonpathogen - protein of unknown function DUF433 Mvan_4355 2 COG2442 COG2442, Uncharacterized conserved protein Function unknown 120405150 Common - ATPase associated with various cellular activities, AAA_5 Mvan_4196 87 COG0714 COG0714, MoxR-like ATPases General function prediction only 120403041 Common - ABC transporter-related protein Mvan_2047 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 120405537 Common - transcriptional regulator, TetR family Mvan_4585 5 COG1309 AcrR, Transcriptional regulator Transcription 120405168 Common - hypothetical protein Mvan_4214 4 None None None 120401389 Common - virulence factor Mce family protein Mvan_0364 10 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120402178 Common - hypothetical protein Mvan_1166 6 COG2353 COG2353, Uncharacterized conserved protein Function unknown 120404116 Common - protein of unknown function DUF881 Mvan_3137 25 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 120404120 Common - ABC transporter-related protein Mvan_3141 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 120402644 Common - hypothetical protein Mvan_1638 1 None None None 120402000 Common - hypothetical protein Mvan_0985 1 None None None 120405180 Common - phospholipid/glycerol acyltransferase Mvan_4226 36 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 120405967 Nonpathogen - hypothetical protein Mvan_5018 1 None None None 120404731 Common - hypothetical protein Mvan_3772 1 None None None 120406269 Common - cobalamin synthesis protein, P47K Mvan_5321 131 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 120406557 Common - Alcohol dehydrogenase, zinc-binding domain protein Mvan_5615 190 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 120403705 Common - protoheme IX farnesyltransferase Mvan_2721 167 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 120406856 Common - beta-lactamase Mvan_5916 9 COG2367 PenP, Beta-lactamase class A Defense mechanisms 120406994 Common - transcriptional regulator, Fis family Mvan_6065 155 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 120403731 Common - NLP/P60 protein Mvan_2747 92 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 120404621 Common - NLP/P60 protein Mvan_3656 93 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 120406207 Common - acetyl-CoA acetyltransferase Mvan_5259 178 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120402075 Common - transcriptional regulator, TetR family Mvan_1060 26 COG1309 AcrR, Transcriptional regulator Transcription 120406966 Common - glycosyl transferase, family 51 Mvan_6036 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 120402264 Common rplJ 50S ribosomal protein L10 Mvan_1252 200 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 120403194 Common - Mg chelatase, subunit ChlI Mvan_2203 189 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 120401622 Common - GntR domain protein Mvan_0606 69 COG2186 FadR, Transcriptional regulators Transcription 120403784 Common - nicotinate-nucleotide pyrophosphorylase Mvan_2800 203 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 120401960 Common - short-chain dehydrogenase/reductase SDR Mvan_0945 170 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 120405581 Common - sulfatase Mvan_4629 81 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 120401962 Common - naphthoate synthase Mvan_0947 177 COG0447 MenB, Dihydroxynaphthoic acid synthase Coenzyme metabolism 120402675 Common - Rhodanese domain protein Mvan_1669 144 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 120403537 Common - UspA domain protein Mvan_2549 23 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 120403213 Common - phosphatidate cytidylyltransferase Mvan_2222 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 120403398 Common - (NiFe) hydrogenase maturation protein HypF Mvan_2407 109 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 120406849 Common - Abortive infection protein Mvan_5908 9 None None None 120405873 Nonpathogen - hypothetical protein Mvan_4923 1 None None None 120406578 Common - RDD domain containing protein Mvan_5636 2 None None None 120405670 Common - Cl- channel, voltage-gated family protein Mvan_4719 87 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 120406353 Common - type II secretion system protein Mvan_5405 11 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 120401617 Common - protein of unknown function DUF1503 Mvan_0601 9 None None None 120404351 Common - hypothetical protein Mvan_3377 6 None None None 120403589 Common - hypothetical protein Mvan_2604 76 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 120405648 Common - sodium:dicarboxylate symporter Mvan_4696 160 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 120401258 Common - acyl-CoA synthetase Mvan_0232 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120406165 Common - cytochrome P450 Mvan_5217 87 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120403513 Common - hypothetical protein Mvan_2525 2 None None None 120403486 Common - Clp N terminal domain protein Mvan_2497 53 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 120403476 Common - methionine-R-sulfoxide reductase Mvan_2487 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 120403054 Common nrdF ribonucleotide-diphosphate reductase subunit beta Mvan_2060 151 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 120405479 Common - hypothetical protein Mvan_4527 17 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 120405057 Common - protein of unknown function UPF0089 Mvan_4103 27 COG4908 COG4908, Uncharacterized protein containing a NRPS condensation (elongation) domain General function prediction only 120401867 Common - short-chain dehydrogenase/reductase SDR Mvan_0852 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 120404766 Common - acyl-CoA dehydrogenase domain protein Mvan_3808 117 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120405779 Common - hypothetical protein Mvan_4829 10 None None None 120405445 Common - sec-independent translocase Mvan_4493 6 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 120406344 Common - DNA topoisomerase I Mvan_5396 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 120404294 Common - putative transposase, IS891/IS1136/IS1341 family Mvan_3319 71 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 120406288 Common - transcriptional regulator, CarD family Mvan_5340 84 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 120406631 Common - hypothetical protein Mvan_5689 1 None None None 120401511 Common - short-chain dehydrogenase/reductase SDR Mvan_0489 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120403341 Common - polynucleotide phosphorylase/polyadenylase Mvan_2350 237 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 120402431 Common - peroxiredoxin Mvan_1420 223 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 120401524 Nonpathogen - hypothetical protein Mvan_0502 1 None None None 120402916 Common - putative transcriptional regulator, MerR family Mvan_1919 131 COG0789 SoxR, Predicted transcriptional regulators Transcription 120402493 Common alr alanine racemase Mvan_1484 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 120403435 Common - alpha/beta hydrolase fold Mvan_2445 187 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120403556 Common - hypothetical protein Mvan_2570 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 120406199 Common - polysaccharide biosynthesis protein Mvan_5251 103 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 120401059 Nonpathogen - hypothetical protein Mvan_0031 1 None None None 120405752 Common - hydrolase, TatD family Mvan_4802 233 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 120403835 Common - virulence factor Mce family protein Mvan_2851 8 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120402310 Common - glycosyl transferase, family 2 Mvan_1299 106 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 120405349 Common - virulence factor Mce family protein Mvan_4396 8 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120406797 Common - major facilitator superfamily MFS_1 Mvan_5855 53 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120402631 Common - Enoyl-CoA hydratase/isomerase Mvan_1625 179 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120403471 Common hemE uroporphyrinogen decarboxylase Mvan_2481 177 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 120406307 Common - Lsr2 Mvan_5359 17 None None None 120401255 Nonpathogen - hypothetical protein Mvan_0229 1 None None None 120401446 Common - peptidase S8 and S53, subtilisin, kexin, sedolisin Mvan_0421 76 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 120403229 Common - hypothetical protein Mvan_2238 1 None None None 120403293 Common - Magnesium chelatase Mvan_2302 67 COG1239 ChlI, Mg-chelatase subunit ChlI Coenzyme metabolism 120404667 Common - peptidase M23B Mvan_3705 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 120402709 Common - protein of unknown function DUF218 Mvan_1708 13 COG1434 COG1434, Uncharacterized conserved protein Function unknown 120405378 Common - glycosyl transferase, family 39 Mvan_4425 17 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 120404712 Common - hypothetical protein Mvan_3753 27 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 120403385 Common - N-acetylglutamate synthase Mvan_2394 90 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 120405916 Common - short-chain dehydrogenase/reductase SDR Mvan_4967 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120401896 Common - 5'-methylthioadenosine phosphorylase Mvan_0881 135 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 120404393 Common - Amidohydrolase 3 Mvan_3420 80 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 120401177 Common - RNA polymerase factor sigma-70 Mvan_0149 161 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 120401687 Common - hypothetical protein Mvan_0672 14 None None None 120403668 Common - primosome assembly protein PriA Mvan_2684 190 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 120403738 Common hemH ferrochelatase Mvan_2754 83 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 120403629 Common - peptidase A24A, prepilin type IV Mvan_2644 14 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 120405114 Common - cytochrome P450 Mvan_4160 66 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120402051 Nonpathogen - hypothetical protein Mvan_1036 1 None None None 120404631 Nonpathogen - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Mvan_3667 1 None None None 120405951 Common - regulatory protein, LuxR Mvan_5002 32 COG3899 COG3899, Predicted ATPase General function prediction only 120406870 Nonpathogen - hypothetical protein Mvan_5930 1 None None None 120405506 Common - nitroreductase Mvan_4554 24 COG0778 NfnB, Nitroreductase Energy production and conversion 120405780 Common - hypothetical protein Mvan_4830 3 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 120405242 Common - beta-lactamase-like protein Mvan_4288 55 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 120405133 Common - ferredoxin 1 Mvan_4179 29 COG1141 Fer, Ferredoxin Energy production and conversion 120405826 Common - Succinate-semialdehyde dehydrogenase (NAD(P)(+)) Mvan_4876 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 120405157 Common - hypothetical protein Mvan_4203 1 None None None 120403275 Common - transcriptional regulator, winged helix family Mvan_2284 36 COG3903 COG3903, Predicted ATPase General function prediction only 120403246 Common - putative conserved transmembrane protein Mvan_2255 4 None None None 120406702 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mvan_5760 16 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 120401532 Common - hypothetical protein Mvan_0510 1 None None None 120401569 Common - hypothetical protein Mvan_0548 3 None None None 120405883 Common - hypothetical protein Mvan_4933 3 None None None 120404262 Common - transcriptional regulator, TetR family Mvan_3287 27 COG1309 AcrR, Transcriptional regulator Transcription 120406188 Nonpathogen - PE-PGRS family protein Mvan_5240 1 None None None 120401052 Common - protein kinase Mvan_0024 158 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 120404019 Common - regulatory protein, ArsR Mvan_3039 59 COG1777 COG1777, Predicted transcriptional regulators Transcription 120402212 Common - Alkanesulfonate monooxygenase Mvan_1200 81 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120404148 Common - hypothetical protein Mvan_3169 2 None None None 120406842 Common - major facilitator superfamily MFS_1 Mvan_5900 8 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120404332 Common - hypothetical protein Mvan_3358 15 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 120406569 Common - FAD linked oxidase domain protein Mvan_5627 58 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 120406439 Common - Catalase Mvan_5493 127 COG0753 KatE, Catalase Inorganic ion transport and metabolism 120402461 Nonpathogen - hypothetical protein Mvan_1451 1 None None None 120403860 Common - Enoyl-CoA hydratase/isomerase Mvan_2877 185 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120402038 Common - binding-protein-dependent transport systems inner membrane component Mvan_1023 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 120405470 Common - transcriptional regulator, LysR family Mvan_4518 188 COG0583 LysR, Transcriptional regulator Transcription 120406845 Common - hypothetical protein Mvan_5904 11 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 120402056 Common - peptidase S15 Mvan_1041 9 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 120402107 Common - DNA-cytosine methyltransferase Mvan_1093 126 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 120405270 Common - Carboxymuconolactone decarboxylase Mvan_4316 11 COG2128 COG2128, Uncharacterized conserved protein Function unknown 120401238 Common - glycosyl transferase, family 2 Mvan_0211 175 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 120402948 Common - major facilitator superfamily MFS_1 Mvan_1951 210 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120402063 Common - ANTAR domain protein Mvan_1048 7 None None None 120402667 Common - anti-sigma-factor antagonist Mvan_1661 1 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 120406657 Common - hypothetical protein Mvan_5715 12 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 120403986 Common - HAD-superfamily subfamily IB hydrolase, TIGR01490 Mvan_3004 91 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 120404509 Common - hypothetical protein Mvan_3537 15 None None None 120405272 Nonpathogen - hypothetical protein Mvan_4318 2 None None None 120402622 Common - short-chain dehydrogenase/reductase SDR Mvan_1616 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120406516 Common - UbiC transcription regulator-associated domain protein Mvan_5574 114 COG2188 PhnF, Transcriptional regulators Transcription 120406589 Common - phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase Mvan_5647 61 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 120403463 Common - TrkA-N domain protein Mvan_2473 105 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 120406713 Nonpathogen - hypothetical protein Mvan_5771 1 None None None 120403448 Common - hypothetical protein Mvan_2458 2 None None None 120402961 Common - acyl-CoA dehydrogenase domain protein Mvan_1965 150 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120401298 Common - acyl-CoA synthetase Mvan_0272 198 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120401489 Common - hypothetical protein Mvan_0465 3 None None None 120406864 Common - hypothetical protein Mvan_5924 6 None None None 120401720 Common - putative conserved membrane protein Mvan_0705 6 None None None 120406613 Nonpathogen - superoxide dismutase Mvan_5671 13 None None None 120405511 Common - signal transduction histidine kinase, LytS Mvan_4559 107 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 120404613 Common - hypothetical protein Mvan_3646 5 None None None 120405016 Common - hypothetical protein Mvan_4062 1 None None None 120403353 Common - hydrogenase expression/formation protein HypE Mvan_2362 120 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 120406895 Common - transposase IS3/IS911 family protein Mvan_5960 4 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 120401832 Common - hypothetical protein Mvan_0817 2 None None None 120403408 Common - hydrogenase nickel insertion protein HypA Mvan_2418 93 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 120401293 Common - short chain dehydrogenase Mvan_0267 225 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 120403261 Common - transcriptional regulator, TetR family Mvan_2270 1 COG1309 AcrR, Transcriptional regulator Transcription 120401880 Common - Phosphoglycerate mutase Mvan_0865 53 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 120406060 Common - Cupin 2, conserved barrel domain protein Mvan_5112 4 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 120403798 Common - anthranilate synthase component I Mvan_2814 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 120405852 Common - hypothetical protein Mvan_4902 37 None None None 120406924 Nonpathogen - dual specificity protein phosphatase Mvan_5991 1 COG2453 CDC14, Predicted protein-tyrosine phosphatase Signal transduction mechanisms 120402747 Nonpathogen - hypothetical protein Mvan_1747 1 None None None 120401585 Common - hypothetical protein Mvan_0567 2 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 120401436 Common - AAA ATPase, central domain protein Mvan_0411 70 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 120406035 Common - cell envelope-related transcriptional attenuator Mvan_5087 60 COG1316 LytR, Transcriptional regulator Transcription 120402894 Common - hypothetical protein Mvan_1896 13 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 120404697 Nonpathogen - hypothetical protein Mvan_3738 1 None None None 120403265 Common - hypothetical protein Mvan_2274 3 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120405602 Nonpathogen - hypothetical protein Mvan_4650 1 None None None 120403113 Common - low molecular weight protein antigen 6 (CFP-6) Mvan_2121 5 None None None 120404109 Common - Thioesterase Mvan_3130 50 COG3208 GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 120403743 Common - band 7 protein Mvan_2759 219 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 120402253 Common - ABC-1 domain protein Mvan_1241 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 120405498 Common - nitrate reductase, alpha subunit Mvan_4546 106 COG5013 NarG, Nitrate reductase alpha subunit Energy production and conversion 120406786 Common - MaoC domain protein dehydratase Mvan_5844 41 COG2030 MaoC, Acyl dehydratase Lipid metabolism 120402182 Common - Rv0623 family protein transcription factor Mvan_1170 6 COG4423 COG4423, Uncharacterized protein conserved in bacteria Function unknown 120405856 Common - monooxygenase, FAD-binding Mvan_4906 73 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 120404094 Common - nitroreductase Mvan_3115 28 COG0778 NfnB, Nitroreductase Energy production and conversion 120401393 Common - virulence factor Mce family protein Mvan_0368 23 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120406086 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase Mvan_5138 184 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 120404679 Common - putative conserved lipoprotein LpqU Mvan_3717 25 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 120404603 Common - putative conserved integral membrane protein Mvan_3635 13 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 120403148 Common - hypothetical protein Mvan_2156 24 None None None 120405817 Nonpathogen - hypothetical protein Mvan_4867 2 None None None 120405023 Common - NAD-glutamate dehydrogenase Mvan_4069 77 COG2902 COG2902, NAD-specific glutamate dehydrogenase Amino acid transport and metabolism 120402279 Common - hypothetical protein Mvan_1268 1 None None None 120404006 Nonpathogen - hypothetical protein Mvan_3026 1 None None None 120404814 Nonpathogen - hypothetical protein Mvan_3856 1 COG5164 SPT5, Transcription elongation factor Transcription 120402336 Common - TenA/THI-4 protein Mvan_1325 20 COG5424 COG5424, Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C Coenzyme metabolism 120406327 Common - hypothetical protein Mvan_5379 22 COG5282 COG5282, Uncharacterized conserved protein Function unknown 120404075 Common - hypothetical protein Mvan_3096 12 None None None 120404051 Common - hypothetical protein Mvan_3072 1 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 120404553 Common - lipoyl synthase Mvan_3582 191 COG0320 LipA, Lipoate synthase Coenzyme metabolism 120403770 Common - glycogen debranching enzyme GlgX Mvan_2786 143 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 120404916 Common - Transglycosylase domain protein Mvan_3962 12 None None None 120405336 Common - luciferase family protein Mvan_4383 9 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120406827 Common - acyl-CoA dehydrogenase domain protein Mvan_5885 144 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120404788 Common - CBS domain containing protein Mvan_3830 220 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 120402380 Common - cyclic nucleotide-binding protein Mvan_1369 214 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 120404233 Nonpathogen - hypothetical protein Mvan_3257 1 None None None 120403867 Common - short-chain dehydrogenase/reductase SDR Mvan_2884 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 120404671 Common - hypothetical protein Mvan_3709 18 COG3336 COG3336, Predicted membrane protein Function unknown 120404492 Common - cell division protein FtsZ Mvan_3520 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 120401985 Common - AMP-dependent synthetase and ligase Mvan_0970 219 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120401507 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Mvan_0485 19 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 120405946 Nonpathogen - hypothetical protein Mvan_4997 1 None None None 120404061 Common ureC urease subunit alpha Mvan_3082 96 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 120405622 Common - cystathionine gamma-synthase Mvan_4670 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 120403097 Common - aminotransferase, class V Mvan_2105 235 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 120403544 Common - hypothetical protein Mvan_2557 5 None None None 120406606 Common - Abortive infection protein Mvan_5664 33 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 120401946 Common - transcriptional regulator, GntR family Mvan_0931 101 COG1802 GntR, Transcriptional regulators Transcription 120406743 Common - hypothetical protein Mvan_5801 9 COG3934 COG3934, Endo-beta-mannanase Carbohydrate transport and metabolism 120403840 Common - hypothetical protein Mvan_2857 1 None None None 120404534 Common - putative conserved integral membrane protein Mvan_3563 18 None None None 120401826 Common - deoxyribose-phosphate aldolase Mvan_0811 138 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 120401031 Common - 6-phosphogluconate dehydrogenase-like protein Mvan_0003 181 COG1023 Gnd, Predicted 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 120402722 Common - biotin--acetyl-CoA-carboxylase ligase Mvan_1722 223 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 120403173 Common - signal recognition particle protein Mvan_2181 246 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 120403931 Common - Methyltransferase type 11 Mvan_2948 189 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 120404556 Common - glutamine synthetase, type I Mvan_3585 224 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 120404584 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mvan_3616 135 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 120402500 Common - hypothetical protein Mvan_1491 1 None None None 120405820 Common sucC succinyl-CoA synthetase subunit beta Mvan_4870 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 120402839 Common - Alcohol dehydrogenase, zinc-binding domain protein Mvan_1841 171 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 120403978 Common - hypothetical protein Mvan_2996 2 None None None 120402550 Common - hypothetical protein Mvan_1543 32 None None None 120402888 Common - hypothetical protein Mvan_1890 5 None None None 120403132 Common - hypothetical protein Mvan_2140 16 COG1920 COG1920, Uncharacterized conserved protein Function unknown 120406774 Common - hypothetical protein Mvan_5832 18 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 120406950 Common - HpcH/HpaI aldolase Mvan_6019 74 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 120405427 Common - drug resistance transporter, Bcr/CflA subfamily Mvan_4475 134 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120404129 Common - amidohydrolase Mvan_3150 147 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 120405684 Common - alpha/beta hydrolase fold Mvan_4733 135 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120405495 Common - respiratory nitrate reductase, gamma subunit Mvan_4543 58 COG2181 NarI, Nitrate reductase gamma subunit Energy production and conversion 120404084 Common - Cutinase Mvan_3105 3 None None None 120401178 Common - alpha/beta hydrolase fold Mvan_0150 152 COG2267 PldB, Lysophospholipase Lipid metabolism 120403146 Common - Dak phosphatase Mvan_2154 46 COG1461 COG1461, Predicted kinase related to dihydroxyacetone kinase General function prediction only 120402806 Common - UvrD/REP helicase Mvan_1807 229 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 120402617 Common - amidohydrolase Mvan_1611 149 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 120404048 Common - putative phosphoketolase Mvan_3069 65 COG3957 COG3957, Phosphoketolase Carbohydrate transport and metabolism 120406692 Common - Kojibiose phosphorylase Mvan_5750 50 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 120406677 Common - hypothetical protein Mvan_5735 58 COG3281 Ble, Uncharacterized protein, probably involved in trehalose biosynthesis Carbohydrate transport and metabolism 120403574 Common - beta-lactamase domain protein Mvan_2589 207 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 120402509 Nonpathogen - hypothetical protein Mvan_1500 9 None None None 120404867 Common - hypothetical protein Mvan_3913 18 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 120401243 Common - glycosyl transferase, family 2 Mvan_0217 188 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 120404825 Nonpathogen - PE-PGRS family protein Mvan_3867 1 COG5164 SPT5, Transcription elongation factor Transcription 120404525 Common - transposase, IS4 family protein Mvan_3553 5 None None None 120406577 Common - protein kinase Mvan_5635 151 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 120406666 Common - hypothetical protein Mvan_5724 5 None None None 120401765 Common - CDP-diacylglycerol--serine O-phosphatidyltransferase Mvan_0750 121 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 120405211 Common - ferredoxin Mvan_4257 98 COG0633 Fdx, Ferredoxin Energy production and conversion 120402317 Common rplD 50S ribosomal protein L4 Mvan_1306 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 120405414 Nonpathogen - hypothetical protein Mvan_4462 1 None None None 120402895 Common - homogentisate 1,2-dioxygenase Mvan_1897 44 COG3508 HmgA, Homogentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 120401479 Common - transposase, mutator type Mvan_0454 80 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 120402237 Common - hypothetical protein Mvan_1225 17 None None None 120406959 Nonpathogen - hypothetical protein Mvan_6028 1 None None None 120403365 Common - dihydrodipicolinate reductase Mvan_2374 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 120401695 Common - hypothetical protein Mvan_0680 4 None None None 120402281 Common - enoyl-CoA hydratase Mvan_1270 173 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120401133 Common - aldehyde dehydrogenase Mvan_0105 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 120402881 Common - NADH dehydrogenase subunit C Mvan_1883 173 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 120401418 Common - acyl-CoA dehydrogenase domain protein Mvan_0393 133 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120401607 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mvan_0591 21 None None None 120402997 Common - hypothetical protein Mvan_2002 7 COG3688 COG3688, Predicted RNA-binding protein containing a PIN domain General function prediction only 120404404 Common - transcriptional regulator, TetR family Mvan_3432 44 COG1309 AcrR, Transcriptional regulator Transcription 120403847 Common - thioesterase superfamily protein Mvan_2864 14 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 120404706 Common - phage integrase family protein Mvan_3747 93 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 120404348 Common - aminoglycoside phosphotransferase Mvan_3374 15 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 120402410 Common - hypothetical protein Mvan_1399 28 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 120406594 Common - LGFP repeat protein Mvan_5652 19 COG5479 COG5479, Uncharacterized protein potentially involved in peptidoglycan biosynthesis Cell envelope biogenesis, outer membrane 120401089 Common - hypothetical protein Mvan_0061 39 COG2388 COG2388, Predicted acetyltransferase General function prediction only 120404746 Common - AzlC family protein Mvan_3787 77 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 120406879 Common - phage integrase family protein Mvan_5941 6 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 120406984 Common - hypothetical protein Mvan_6055 1 None None None 120401186 Common - hypothetical protein Mvan_0158 9 None None None 120402756 Common - hypothetical protein Mvan_1756 1 None None None 120406008 Common - Integrase, catalytic region Mvan_5060 145 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 120402399 Common - magnesium-translocating P-type ATPase Mvan_1388 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 120404026 Common - hypothetical protein Mvan_3047 7 None None None 120404341 Common - hypothetical protein Mvan_3367 5 None None None 120405267 Common - acyl-CoA dehydrogenase domain protein Mvan_4313 138 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120401144 Common - acyl-CoA dehydrogenase domain protein Mvan_0116 152 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120405662 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Mvan_4710 45 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 120403374 Common - protein of unknown function DUF1006 Mvan_2383 58 COG3214 COG3214, Uncharacterized protein conserved in bacteria Function unknown 120404425 Common - transcriptional regulator, BadM/Rrf2 family Mvan_3453 102 COG1959 COG1959, Predicted transcriptional regulator Transcription 120404166 Common - cytochrome P450 Mvan_3187 84 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120403128 Common leuD isopropylmalate isomerase small subunit Mvan_2136 209 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 120406103 Common - 6-phosphogluconate dehydrogenase, NAD-binding Mvan_5155 164 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 120402715 Common - phosphoribosylaminoimidazole carboxylase, catalytic subunit Mvan_1714 233 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 120405764 Common - hypothetical protein Mvan_4814 1 None None None 120404219 Common - heavy metal translocating P-type ATPase Mvan_3242 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 120406426 Common - transcriptional regulator, TetR family Mvan_5480 7 COG1309 AcrR, Transcriptional regulator Transcription 120402557 Common - Methylenetetrahydrofolate dehydrogenase (NADP(+)) Mvan_1550 223 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 120406319 Common folE GTP cyclohydrolase I Mvan_5371 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 120401544 Common - drug resistance transporter, EmrB/QacA subfamily Mvan_0523 221 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120402235 Common - hypothetical protein Mvan_1223 16 None None None 120402582 Common - RNA polymerase sigma factor SigJ Mvan_1575 51 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 120405096 Common - hypothetical protein Mvan_4142 1 None None None 120406133 Common - Carbon-monoxide dehydrogenase (acceptor) Mvan_5185 86 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 120401790 Common - putative antibiotic-transport integral membrane leucine and valine rich protein ABC transporter Mvan_0775 6 None None None 120402534 Common - OsmC family protein Mvan_1525 90 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 120404748 Common - peptidase M4, thermolysin Mvan_3789 46 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 120401205 Common - ErfK/YbiS/YcfS/YnhG family protein Mvan_0177 23 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 120402194 Common - hypothetical protein Mvan_1182 4 None None None 120403722 Common - protein of unknown function DUF59 Mvan_2738 144 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 120406330 Common - hypothetical protein Mvan_5382 22 COG3195 COG3195, Uncharacterized protein conserved in bacteria Function unknown 120401116 Common - hypothetical protein Mvan_0088 1 None None None 120407001 Common - Cobyrinic acid a,c-diamide synthase Mvan_6072 231 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 120403905 Common - transcriptional regulator, RpiR family Mvan_2922 58 COG1737 RpiR, Transcriptional regulators Transcription 120401594 Common - transposase IS3/IS911 family protein Mvan_0576 36 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 120402086 Common - band 7 protein Mvan_1071 204 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 120402189 Common - hypothetical protein Mvan_1177 10 None None None 120401421 Common - hypothetical protein Mvan_0396 66 COG3285 COG3285, Predicted eukaryotic-type DNA primase DNA replication, recombination, and repair 120403456 Common - putative conserved alanine rich transmembrane protein Mvan_2466 11 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 120403885 Common - hypothetical protein Mvan_2902 3 None None None 120406804 Common - major facilitator superfamily MFS_1 Mvan_5862 17 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120403677 Common - riboflavin synthase subunit alpha Mvan_2693 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 120401501 Common - phage integrase family protein Mvan_0479 5 None None None 120406119 Common - short-chain dehydrogenase/reductase SDR Mvan_5171 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120402925 Common - Methyltransferase type 11 Mvan_1928 54 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 120406674 Common - binding-protein-dependent transport systems inner membrane component Mvan_5732 178 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 120403003 Common - aldehyde dehydrogenase Mvan_2009 218 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 120401119 Common - putative conserved membrane protein Mvan_0091 3 None None None 120402818 Common - hypothetical protein Mvan_1819 30 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120402981 Common - Enoyl-CoA hydratase/isomerase Mvan_1985 178 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120406218 Common - Alcohol dehydrogenase GroES domain protein Mvan_5270 207 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 120406772 Common - hypothetical protein Mvan_5830 21 None None None 120406543 Common - Substrate-binding region of ABC-type glycine betaine transport system Mvan_5601 88 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 120404232 Common - helix-turn-helix domain protein Mvan_3256 8 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 120402793 Common - hypothetical protein Mvan_1794 16 None None None 120403232 Common - HpcH/HpaI aldolase Mvan_2241 73 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 120401460 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Mvan_0435 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 120405198 Common - Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B Mvan_4244 22 COG3384 COG3384, Uncharacterized conserved protein Function unknown 120403529 Common - ABC transporter-related protein Mvan_2541 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 120402153 Common - hypothetical protein Mvan_1141 2 None None None 120404985 Common - transcriptional regulator, LysR family Mvan_4031 173 COG0583 LysR, Transcriptional regulator Transcription 120402979 Common - Enoyl-CoA hydratase/isomerase Mvan_1983 154 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120404946 Common - hypothetical protein Mvan_3992 67 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120405308 Nonpathogen - hypothetical protein Mvan_4354 1 None None None 120403559 Common ruvC Holliday junction resolvase Mvan_2573 195 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 120403637 Common nusB transcription antitermination protein NusB Mvan_2652 61 COG0781 NusB, Transcription termination factor Transcription 120401551 Common - protein of unknown function DUF35 Mvan_0530 40 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 120406175 Common - hypothetical protein Mvan_5227 18 None None None 120401068 Common - protein of unknown function DUF222 Mvan_0040 4 None None None 120406749 Common - anti-sigma-factor antagonist Mvan_5807 5 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 120401120 Common - peptidase S8 and S53, subtilisin, kexin, sedolisin Mvan_0092 105 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 120403090 Common - Methyltransferase type 11 Mvan_2098 155 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 120403205 Common - protein of unknown function DUF214 Mvan_2214 1 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 120405399 Common - protein of unknown function DUF305 Mvan_4447 42 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 120402532 Common - hypothetical protein Mvan_1523 36 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 120403777 Common - biotin synthase Mvan_2793 183 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 120401587 Common - protein of unknown function DUF732 Mvan_0569 1 None None None 120406694 Common - luciferase family protein Mvan_5752 57 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120404199 Common - protein tyrosine phosphatase Mvan_3221 136 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 120402340 Common - Rieske (2Fe-2S) domain protein Mvan_1329 73 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 120403605 Common - short-chain dehydrogenase/reductase SDR Mvan_2620 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120404275 Common - hypothetical protein Mvan_3300 1 None None None 120406839 Common - DNA topoisomerase (ATP-hydrolyzing) Mvan_5897 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 120401933 Common - hypothetical protein Mvan_0918 3 None None None 120402174 Common - putative transcriptional regulator, XRE family Mvan_1162 42 COG1396 HipB, Predicted transcriptional regulators Transcription 120403550 Common - NUDIX hydrolase Mvan_2563 21 COG1704 LemA, Uncharacterized conserved protein Function unknown 120403351 Common - hydrogenase assembly chaperone hypC/hupF Mvan_2360 39 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 120404704 Nonpathogen - hypothetical protein Mvan_3745 1 None None None 120401795 Common - enoyl-CoA hydratase Mvan_0780 176 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120406455 Common - ferredoxin-dependent glutamate synthase Mvan_5512 140 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 120401150 Common - Substrate-binding region of ABC-type glycine betaine transport system Mvan_0122 107 COG4521 TauA, ABC-type taurine transport system, periplasmic component Inorganic ion transport and metabolism 120403845 Common - lipid-transfer protein Mvan_2862 90 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120403500 Nonpathogen - hypothetical protein Mvan_2512 1 None None None 120406982 Common - transposase IS116/IS110/IS902 family protein Mvan_6052 51 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 120404810 Common - beta-ketoacyl synthase Mvan_3852 205 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 120404020 Common - Carboxymuconolactone decarboxylase Mvan_3041 13 COG2128 COG2128, Uncharacterized conserved protein Function unknown 120402862 Common - Alcohol dehydrogenase, zinc-binding domain protein Mvan_1864 176 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 120403914 Common - hypothetical protein Mvan_2931 13 None None None 120403409 Common - alpha/beta hydrolase fold Mvan_2419 62 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 120406653 Nonpathogen - hypothetical protein Mvan_5711 1 None None None 120402717 Common - PilT protein domain protein Mvan_1717 2 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 120403714 Common - ABC transporter-related protein Mvan_2730 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 120402913 Common smpB SsrA-binding protein Mvan_1916 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 120401383 Common - luciferase family protein Mvan_0358 35 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120405281 Common atpC F0F1 ATP synthase subunit epsilon Mvan_4327 130 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 120404458 Common - hypothetical protein Mvan_3486 5 None None None 120406813 Common - phosphonate metabolism protein PhnI Mvan_5871 44 COG3626 PhnI, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 120404954 Common - 3,4-dihydroxy-2-butanone 4-phosphate synthase Mvan_4000 221 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 120402417 Common - hypothetical protein Mvan_1406 1 None None None 120402634 Common - fatty acid desaturase Mvan_1628 33 COG3239 DesA, Fatty acid desaturase Lipid metabolism 120404548 Common - Alkaline phosphatase Mvan_3577 82 COG1785 PhoA, Alkaline phosphatase Inorganic ion transport and metabolism 120403016 Common - amidohydrolase 2 Mvan_2022 18 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 120402933 Common - Transport protein Mvan_1936 81 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 120405996 Common moaA molybdenum cofactor biosynthesis protein A Mvan_5047 196 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 120405849 Common - Hydantoinase B/oxoprolinase Mvan_4899 92 COG0146 HyuB, N-methylhydantoinase B/acetone carboxylase, alpha subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120402167 Common - secreted protein Mvan_1155 37 None None None 120403419 Common - RNA modification enzyme, MiaB family Mvan_2429 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 120404324 Common - excinuclease ABC subunit B Mvan_3350 224 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 120402307 Common - Radical SAM domain protein Mvan_1296 170 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 120402199 Common - hypothetical protein Mvan_1187 11 None None None 120402850 Common - peptidase C26 Mvan_1852 136 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 120403241 Common - acyl-CoA thioesterase Mvan_2250 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 120404578 Nonpathogen - hypothetical protein Mvan_3609 1 None None None 120402169 Common - transcriptional regulator, TetR family Mvan_1157 35 COG1309 AcrR, Transcriptional regulator Transcription 120402920 Common - hypothetical protein Mvan_1923 3 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 120403729 Common - aconitate hydratase 1 Mvan_2745 199 COG1048 AcnA, Aconitase A Energy production and conversion 120405234 Nonpathogen - hypothetical protein Mvan_4280 1 None None None 120405836 Common - UDP-glucuronosyl/UDP-glucosyltransferase Mvan_4886 39 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 120406625 Common - hypothetical protein Mvan_5683 71 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 120404486 Common - hypothetical protein Mvan_3514 1 None None None 120404390 Common - hypothetical protein Mvan_3417 18 None None None 120406041 Common - protein tyrosine phosphatase Mvan_5093 93 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 120405360 Common - putative GAF sensor protein Mvan_4407 41 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 120405005 Common - Formamidopyrimidine-DNA glycolase Mvan_4051 178 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 120403038 Common - hypothetical protein Mvan_2044 9 None None None 120404381 Common - Carboxylesterase, type B Mvan_3408 91 COG2272 PnbA, Carboxylesterase type B Lipid metabolism 120406246 Common - acetyl-CoA synthetase Mvan_5298 206 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 120402205 Common - diguanylate cyclase Mvan_1193 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 120405713 Common - two component transcriptional regulator, winged helix family Mvan_4763 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 120403652 Common - DNA-directed RNA polymerase subunit omega Mvan_2668 21 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 120401168 Common - putative conserved MCE associated membrane protein Mvan_0140 2 None None None 120406351 Nonpathogen - hypothetical protein Mvan_5403 1 None None None 120404994 Common clpP ATP-dependent Clp protease proteolytic subunit Mvan_4040 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 120403611 Common - transcriptional regulator, DeoR family Mvan_2626 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 120402972 Common - acetyl-CoA acetyltransferase Mvan_1976 183 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120406486 Common ligC ATP-dependent DNA ligase Mvan_5543 98 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 120406053 Common - hypothetical protein Mvan_5105 16 None None None 120404856 Common - hypothetical protein Mvan_3901 1 None None None 120405711 Common - K+ transporting ATPase, KdpC subunit Mvan_4761 93 COG2156 KdpC, K+-transporting ATPase, c chain Inorganic ion transport and metabolism 120404757 Common - hypothetical protein Mvan_3799 22 None None None 120405504 Common - hypothetical protein Mvan_4552 4 COG5373 COG5373, Predicted membrane protein Function unknown 120402376 Common - dTDP-glucose 4,6-dehydratase Mvan_1365 231 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 120402023 Common - acyl-CoA thioesterase Mvan_1008 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 120405320 Nonpathogen - hypothetical protein Mvan_4366 1 None None None 120405740 Common - NADH:flavin oxidoreductase/NADH oxidase Mvan_4790 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 120402220 Common - exodeoxyribonuclease V, alpha subunit Mvan_1208 133 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 120404374 Common - transcriptional regulator, LysR family Mvan_3401 118 COG0583 LysR, Transcriptional regulator Transcription 120406758 Nonpathogen - cyclase/dehydrase Mvan_5816 3 COG5637 COG5637, Predicted integral membrane protein Function unknown 120404346 Common - regulatory protein, ArsR Mvan_3372 53 COG0640 ArsR, Predicted transcriptional regulators Transcription 120402290 Common rpsL 30S ribosomal protein S12 Mvan_1279 246 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 120406830 Common - hypothetical protein Mvan_5888 2 None None None 120406383 Common - beta-lactamase domain protein Mvan_5436 121 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 120402203 Common - hypothetical protein Mvan_1191 8 None None None 120403956 Common - hypothetical protein Mvan_2974 129 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 120402334 Common - transcriptional regulator, CdaR Mvan_1323 38 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 120403880 Common - NAD-dependent epimerase/dehydratase Mvan_2897 148 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120405041 Common - HpcH/HpaI aldolase Mvan_4087 108 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 120402692 Common - hypothetical protein Mvan_1687 2 None None None 120401876 Common - transcriptional regulator, CdaR Mvan_0861 16 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 120403061 Nonpathogen - hypothetical protein Mvan_2069 1 None None None 120403693 Common - protein of unknown function DUF224, cysteine-rich region domain protein Mvan_2709 158 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 120405069 Common - Hydrogen dehydrogenase Mvan_4115 179 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 120402688 Nonpathogen - hypothetical protein Mvan_1683 1 None None None 120403921 Common - glucose-methanol-choline oxidoreductase Mvan_2938 88 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 120405822 Common - hypothetical protein Mvan_4872 1 None None None 120406751 Common - hypothetical protein Mvan_5809 7 None None None 120402382 Common - response regulator receiver modulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mvan_1371 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 120403478 Common - TAP domain protein Mvan_2489 27 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120403227 Common - hypothetical protein Mvan_2236 17 None None None 120406821 Nonpathogen - Hemerythrin HHE cation binding domain protein Mvan_5879 3 None None None 120401872 Common - hypothetical protein Mvan_0857 1 None None None 120403327 Common - two component transcriptional regulator, winged helix family Mvan_2336 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 120403457 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase Mvan_2467 181 COG0756 Dut, dUTPase Nucleotide transport and metabolism 120405482 Common - hypothetical protein Mvan_4530 4 None None None 120404809 Common - protein of unknown function DUF222 Mvan_3851 7 None None None 120406254 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mvan_5306 25 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 120401633 Common - YibE/F family protein Mvan_0617 27 COG5438 COG5438, Predicted multitransmembrane protein Function unknown 120404993 Common - ATP-dependent Clp protease proteolytic subunit Mvan_4039 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 120404892 Common - cation efflux protein Mvan_3938 13 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 120401865 Common - putative conserved transmembrane protein Mvan_0850 4 None None None 120405981 Common - hypothetical protein Mvan_5032 7 None None None 120401944 Common - transcriptional regulator, TetR family Mvan_0929 103 COG1309 AcrR, Transcriptional regulator Transcription 120406792 Common - protein of unknown function DUF309 Mvan_5850 17 COG1547 COG1547, Uncharacterized conserved protein Function unknown 120402043 Common - hypothetical protein Mvan_1028 3 None None None 120404360 Common - hypothetical protein Mvan_3386 4 None None None 120404497 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase Mvan_3525 196 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 120405043 Common - acyl-CoA dehydrogenase domain protein Mvan_4089 166 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120405747 Common - protein of unknown function DUF1222 Mvan_4797 9 None None None 120401883 Common - ResB family protein Mvan_0868 18 COG1333 ResB, ResB protein required for cytochrome c biosynthesis Posttranslational modification, protein turnover, chaperones 120401857 Common - MaoC-like dehydratase Mvan_0842 25 COG2030 MaoC, Acyl dehydratase Lipid metabolism 120401492 Common - Cupin 2, conserved barrel domain protein Mvan_0468 35 COG3435 COG3435, Gentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 120402428 Common - peptidase S15 Mvan_1417 76 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 120401324 Common - nitrite reductase (NAD(P)H), small subunit Mvan_0298 45 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 120401236 Common - glycoside hydrolase, family 16 Mvan_0209 10 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 120405367 Common - alpha/beta hydrolase fold Mvan_4414 177 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120403106 Common gatC aspartyl/glutamyl-tRNA amidotransferase subunit C Mvan_2114 71 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 120405382 Common - two component transcriptional regulator, winged helix family Mvan_4429 211 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 120403237 Common - acyl-CoA dehydrogenase domain protein Mvan_2246 138 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120401287 Common - luciferase family protein Mvan_0261 44 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120402392 Common - UspA domain protein Mvan_1381 1 None None None 120405948 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Mvan_4999 44 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 120405698 Common - hypothetical protein Mvan_4748 44 COG3569 COG3569, Topoisomerase IB DNA replication, recombination, and repair 120406458 Common - 2-isopropylmalate synthase Mvan_5515 211 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 120404721 Common - diacylglycerol kinase Mvan_3762 104 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 120405676 Common - hypothetical protein Mvan_4725 5 None None None 120405612 Common - hypothetical protein Mvan_4660 1 None None None 120405971 Common gltA type II citrate synthase Mvan_5022 194 COG0372 GltA, Citrate synthase Energy production and conversion 120403013 Common - Propionyl-CoA carboxylase Mvan_2019 144 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 120403793 Common - Inositol-phosphate phosphatase Mvan_2809 178 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 120403945 Nonpathogen - hypothetical protein Mvan_2962 1 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 120406504 Common - propanediol utilization: dehydratase, small subunit Mvan_5562 13 COG4910 PduE, Propanediol dehydratase, small subunit Secondary metabolites biosynthesis, transport, and catabolism 120405389 Common - metallophosphoesterase Mvan_4436 36 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 120402699 Common - glycosyl transferase, group 1 Mvan_1696 16 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 120403594 Common - Carboxylesterase, type B Mvan_2609 63 COG2272 PnbA, Carboxylesterase type B Lipid metabolism 120406521 Common - cytochrome P450 Mvan_5579 72 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120401412 Common - Inositol 2-dehydrogenase Mvan_0387 79 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 120404980 Common - protein of unknown function DUF156 Mvan_4026 75 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 120406437 Common rpsN 30S ribosomal protein S14 Mvan_5491 205 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 120402569 Common - Serine-type D-Ala-D-Ala carboxypeptidase Mvan_1562 153 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 120405288 Common - F0F1 ATP synthase subunit A Mvan_4334 204 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 120403786 Common - Lysine exporter protein (LYSE/YGGA) Mvan_2802 119 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 120406560 Common - ABC transporter-related protein Mvan_5618 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 120406992 Common - hypothetical protein Mvan_6063 9 None None None 120402144 Common - hypothetical protein Mvan_1131 17 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 120405524 Common - transcriptional regulator, TetR family Mvan_4572 82 COG1309 AcrR, Transcriptional regulator Transcription 120406413 Common - short-chain dehydrogenase/reductase SDR Mvan_5466 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 120402834 Common - hypothetical protein Mvan_1836 2 None None None 120402513 Common - Thiocyanate hydrolase Mvan_1504 21 None None None 120402324 Common - 50S ribosomal protein L29 Mvan_1313 63 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 120401925 Common - putative methyltransferase Mvan_0910 31 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 120401048 Common - protein of unknown function DUF881 Mvan_0020 25 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 120403200 Common rpsB 30S ribosomal protein S2 Mvan_2209 227 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 120401320 Common - GntR domain protein Mvan_0294 129 COG2186 FadR, Transcriptional regulators Transcription 120401807 Common - hypothetical protein Mvan_0792 1 None None None 120406914 Nonpathogen - hypothetical protein Mvan_5981 21 COG0433 COG0433, Predicted ATPase General function prediction only 120406313 Common - NAD-dependent glycerol-3-phosphate dehydrogenase-like protein Mvan_5365 39 COG5495 COG5495, Uncharacterized conserved protein Function unknown 120403819 Common - putative signal transduction histidine kinase Mvan_2835 16 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 120405591 Common - protein of unknown function DUF323 Mvan_4639 108 COG1262 COG1262, Uncharacterized conserved protein Function unknown 120406286 Common cysS cysteinyl-tRNA synthetase Mvan_5338 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 120406023 Nonpathogen - hypothetical protein Mvan_5075 1 None None None 120401575 Common - AAA ATPase Mvan_0555 60 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 120403766 Nonpathogen - hypothetical protein Mvan_2782 1 None None None 120402763 Common - protein of unknown function UPF0089 Mvan_1764 28 None None None 120406601 Common - seryl-tRNA synthetase Mvan_5659 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 120404726 Common - Alcohol dehydrogenase, zinc-binding domain protein Mvan_3767 210 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 120401951 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Mvan_0936 45 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 120401448 Common - hypothetical protein Mvan_0423 4 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 120405325 Nonpathogen - hypothetical protein Mvan_4372 1 None None None 120401735 Common - hypothetical protein Mvan_0720 1 COG4270 COG4270, Predicted membrane protein Function unknown 120403511 Nonpathogen - hypothetical protein Mvan_2523 1 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 120405799 Common - Carbamoyl-phosphate synthase L chain, ATP-binding Mvan_4849 229 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 120402069 Common - glycosidase, PH1107-related Mvan_1054 30 COG2152 COG2152, Predicted glycosylase Carbohydrate transport and metabolism 120403442 Common - hypothetical protein Mvan_2452 8 None None None 120406944 Nonpathogen - RNA polymerase, sigma-24 subunit, ECF subfamily Mvan_6012 1 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 120404714 Common acpP acyl carrier protein Mvan_3755 194 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120402771 Common - protein of unknown function DUF159 Mvan_1772 108 COG2135 COG2135, Uncharacterized conserved protein Function unknown 120404433 Common - protein of unknown function DUF503 Mvan_3461 11 COG1550 COG1550, Uncharacterized protein conserved in bacteria Function unknown 120406342 Common - DNA polymerase III subunit delta' Mvan_5394 216 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 120401708 Common - regulatory protein, ArsR Mvan_0693 71 COG0640 ArsR, Predicted transcriptional regulators Transcription 120405932 Common - cytochrome P450 Mvan_4983 69 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 120404284 Common - arginine repressor Mvan_3309 81 COG1438 ArgR, Arginine repressor Transcription 120405902 Common - aldehyde dehydrogenase Mvan_4953 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 120403732 Common - NLP/P60 protein Mvan_2748 117 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 120405922 Common - transcriptional regulator, TetR family Mvan_4973 9 COG1309 AcrR, Transcriptional regulator Transcription 120402366 Common - aminotransferase, class I and II Mvan_1355 227 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 120403184 Common rplS 50S ribosomal protein L19 Mvan_2192 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 120403878 Common - short-chain dehydrogenase/reductase SDR Mvan_2895 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120404647 Common - hypothetical protein Mvan_3683 52 COG3000 ERG3, Sterol desaturase Lipid metabolism 120401266 Common - Betaine-aldehyde dehydrogenase Mvan_0240 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 120401635 Common - protein of unknown function DUF224, cysteine-rich region domain protein Mvan_0619 102 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 120405837 Common - Methyltransferase type 11 Mvan_4887 13 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 120406764 Common - Amidase Mvan_5822 214 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 120404772 Common dnaG DNA primase Mvan_3814 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 120403289 Common - mycothione/glutathione reductase Mvan_2298 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 120401640 Common - hypothetical protein Mvan_0624 42 COG0699 COG0699, Predicted GTPases (dynamin-related) General function prediction only 120404696 Nonpathogen - hypothetical protein Mvan_3737 1 None None None 120406150 Common - virulence factor Mce family protein Mvan_5202 6 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120406537 Common - hypothetical protein Mvan_5595 8 None None None 120405896 Common - protein of unknown function DUF849 Mvan_4947 8 COG3246 COG3246, Uncharacterized conserved protein Function unknown 120406700 Common - Alcohol dehydrogenase GroES domain protein Mvan_5758 176 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 120405464 Common - ATPas Mvan_4512 6 COG1474 CDC6, Cdc6-related protein, AAA superfamily ATPase DNA replication, recombination, and repair / Posttranslational modification, protein turnover, chaperones 120405392 Common - putative lipoprotein LprB Mvan_4439 3 None None None 120405576 Common - alkylphosphonate utilization operon protein PhnA Mvan_4624 74 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 120406241 Common - solute-binding protein Mvan_5293 89 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 120405890 Common - transcriptional regulator, HxlR family Mvan_4941 106 COG1733 COG1733, Predicted transcriptional regulators Transcription 120405703 Common - short-chain dehydrogenase/reductase SDR Mvan_4753 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120405634 Common - hypothetical protein Mvan_4682 16 COG4425 COG4425, Predicted membrane protein Function unknown 120406730 Common - hypothetical protein Mvan_5788 3 None None None 120403027 Common - hypothetical protein Mvan_2033 3 None None None 120406723 Common - hypothetical protein Mvan_5781 42 COG3651 COG3651, Uncharacterized protein conserved in bacteria Function unknown 120404798 Common - integral membrane sensor signal transduction histidine kinase Mvan_3840 214 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 120403633 Nonpathogen - hypothetical protein Mvan_2648 1 None None None 120406378 Common - NUDIX hydrolase Mvan_5431 45 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 120406869 Common - hypothetical protein Mvan_5929 23 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 120402270 Common - DNA-directed RNA polymerase subunit beta' Mvan_1258 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 120404186 Common - catalase/peroxidase HPI Mvan_3208 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 120405918 Common - hypothetical protein Mvan_4969 5 None None None 120402210 Common - hypothetical protein Mvan_1198 12 None None None 120403334 Common - alpha/beta hydrolase fold Mvan_2343 32 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 120403649 Common pyrF orotidine 5'-phosphate decarboxylase Mvan_2665 64 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 120401914 Common - lipid-transfer protein Mvan_0899 90 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120401364 Common - small multidrug resistance protein Mvan_0339 93 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 120406120 Common - AMP-dependent synthetase and ligase Mvan_5172 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 120406532 Common - Alcohol dehydrogenase GroES domain protein Mvan_5590 209 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 120401304 Common - hypothetical protein Mvan_0278 1 None None None 120404122 Common - hypothetical protein Mvan_3143 26 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 120402548 Common - pentapeptide repeat protein Mvan_1540 83 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 120403155 Common - hypothetical protein Mvan_2163 24 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 120404563 Common - 40-residue YVTN family beta-propeller repeat protein Mvan_3594 94 COG3391 COG3391, Uncharacterized conserved protein Function unknown 120404014 Common - dienelactone hydrolase Mvan_3034 107 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 120401745 Common - exodeoxyribonuclease III Xth Mvan_0730 195 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 120406294 Common - HhH-GPD family protein Mvan_5346 195 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 120405960 Common - peptidylprolyl isomerase, FKBP-type Mvan_5011 131 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 120406446 Common - aspartate-semialdehyde dehydrogenase Mvan_5503 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 120406476 Common - hypothetical protein Mvan_5533 2 None None None 120403703 Common - transaldolase Mvan_2719 144 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 120402525 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein Mvan_1516 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 120405579 Common - hypothetical protein Mvan_4627 4 None None None 120405939 Common - beta-lactamase Mvan_4990 95 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 120406461 Common - response regulator receiver protein Mvan_5518 9 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 120405969 Common - transcriptional regulator, MarR family Mvan_5020 2 COG1846 MarR, Transcriptional regulators Transcription 120404314 Common - beta-lactamase domain protein Mvan_3340 202 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 120403815 Common - protein of unknown function DUF308, membrane Mvan_2831 66 COG3247 HdeD, Uncharacterized conserved protein Function unknown 120403504 Nonpathogen - hypothetical protein Mvan_2516 1 None None None 120405600 Common glpX fructose 1,6-bisphosphatase II Mvan_4648 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 120403426 Common - GTP-binding protein, HSR1-related Mvan_2436 226 COG2262 HflX, GTPases General function prediction only 120404335 Common - DNA polymerase I Mvan_3361 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 120402872 Common - NADH dehydrogenase subunit L Mvan_1874 206 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 120402788 Common - Cobyrinic acid a,c-diamide synthase Mvan_1789 227 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 120401041 Common - Alcohol dehydrogenase GroES domain protein Mvan_0013 163 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 120406643 Common - hypothetical protein Mvan_5701 18 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 120403302 Common - hypothetical protein Mvan_2311 75 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 120402028 Common - helix-turn-helix- domain containing protein, AraC type Mvan_1013 70 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 120401481 Common - phage integrase family protein Mvan_0456 128 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 120405866 Common - PfkB domain protein Mvan_4916 91 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 120406277 Common - major facilitator superfamily MFS_1 Mvan_5329 19 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 120401312 Common - transposase Mvan_0286 69 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 120404845 Common - Excalibur domain protein Mvan_3889 3 None None None 120402798 Common - methylated-DNA-(protein)-cysteine S-methyltransferase Mvan_1799 54 COG3695 COG3695, Predicted methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 120404302 Common - translation initiation factor IF-3 Mvan_3328 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 120404591 Common - putative conserved transmembrane protein Mvan_3623 41 COG3346 COG3346, Uncharacterized conserved protein Function unknown 120404833 Common - sulfate ABC transporter, periplasmic sulfate-binding protein Mvan_3875 99 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 120405735 Common - lipoprotein, putative Mvan_4785 1 None None None 120404226 Nonpathogen - hypothetical protein Mvan_3249 1 None None None 120403077 Common - protein of unknown function DUF161 Mvan_2085 25 COG2364 COG2364, Predicted membrane protein Function unknown 120405880 Common - luciferase family protein Mvan_4930 60 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 120406293 Common - carbonic anhydrase Mvan_5345 150 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 120401977 Common - virulence factor Mce family protein Mvan_0962 11 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120401991 Common - putative conserved transmembrane protein Mvan_0976 5 None None None 120405541 Common - acetyl-CoA acetyltransferases Mvan_4589 187 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 120405032 Common - putative transcriptional regulator, TetR family Mvan_4078 15 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 120403099 Common - LpqA Mvan_2107 1 None None None 120402794 Common - transcriptional regulator, TetR family Mvan_1795 136 COG1309 AcrR, Transcriptional regulator Transcription 120404655 Common - copper resistance D domain protein Mvan_3692 21 COG3336 COG3336, Predicted membrane protein Function unknown 120403072 Common - Alcohol dehydrogenase GroES domain protein Mvan_2080 206 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 120402021 Common - protein of unknown function DUF1100, hydrolase family protein Mvan_1006 31 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 120405552 Common - virulence factor Mce family protein Mvan_4600 13 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120406968 Common - protein of unknown function DUF1707 Mvan_6038 3 None None None 120404596 Common - SOUL heme-binding protein Mvan_3628 26 COG3449 COG3449, DNA gyrase inhibitor DNA replication, recombination, and repair 120403218 Common - transcriptional regulator, TetR family Mvan_2227 9 COG1309 AcrR, Transcriptional regulator Transcription 120406213 Common - short chain dehydrogenase Mvan_5265 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120405351 Common - virulence factor Mce family protein Mvan_4398 58 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 120402403 Common - arginine/ornithine antiporter Mvan_1392 72 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 120406371 Common - hypothetical protein Mvan_5424 9 None None None 120402604 Common - preprotein translocase, SecA subunit Mvan_1598 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 120405088 Common - amidohydrolase 2 Mvan_4134 15 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 120406489 Common - protein of unknown function DUF222 Mvan_5546 5 None None None 120404859 Common - phage integrase family protein Mvan_3904 30 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 120401354 Common - hypothetical protein Mvan_0329 13 None None None 120402605 Common - NLP/P60 protein Mvan_1599 121 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 120404685 Common - hypothetical protein Mvan_3725 5 None None None 120403961 Common - hypothetical protein Mvan_2979 1 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 120402473 Common - hypothetical protein Mvan_1464 2 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 120405081 Common - major facilitator superfamily MFS_1 Mvan_4127 142 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 120405783 Common - Nucleotidyl transferase Mvan_4833 226 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 120404254 Common - Cobyrinic acid a,c-diamide synthase Mvan_3279 229 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 120404507 Common - LppM Mvan_3535 4 None None None 120403023 Common - protein of unknown function DUF81 Mvan_2029 19 COG0730 COG0730, Predicted permeases General function prediction only 120405889 Common - Carotenoid oxygenase Mvan_4940 35 COG3670 COG3670, Lignostilbene-alpha,beta-dioxygenase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 120405437 Common - hypothetical protein Mvan_4485 18 None None None 120401774 Common - type III restriction enzyme, res subunit Mvan_0759 57 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 120405909 Common - short-chain dehydrogenase/reductase SDR Mvan_4960 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 120402959 Common - UspA domain protein Mvan_1963 50 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 120401407 Common - Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase Mvan_0382 199 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 120401273 Common - hypothetical protein Mvan_0247 9 COG3662 COG3662, Uncharacterized protein conserved in bacteria Function unknown 120406263 Common - redox-active disulfide protein 2 Mvan_5315 63 None None None 120402060 Common - fatty acid desaturase Mvan_1045 34 COG3239 DesA, Fatty acid desaturase Lipid metabolism 120403367 Common - hypothetical protein Mvan_2376 27 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 120404897 Common - gamma-glutamyl kinase Mvan_3943 189 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 120405697 Common - hypothetical protein Mvan_4747 8 None None None 120404872 Common - acyl-CoA dehydrogenase domain protein Mvan_3918 30 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 120405456 Common - glycogen synthase Mvan_4504 214 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 120406719 Common - hypothetical protein Mvan_5777 3 None None None 120401215 Common - MmpL11 Mvan_0188 44 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 120404866 Common rpsT 30S ribosomal protein S20 Mvan_3912 207 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 120401451 Common - protein of unknown function DUF222 Mvan_0426 6 None None None 120403971 Common - response regulator receiver protein Mvan_2989 216 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 120405037 Common - enoyl-CoA hydratase Mvan_4083 121 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 120406260 Common - transcriptional regulator, TetR family Mvan_5312 40 COG1309 AcrR, Transcriptional regulator Transcription