Nocardioides sp. JS614 plasmid pNOCA01, complete sequence NC_008697 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 119714073 Common - phage Gp37Gp68 family protein Noca_4766 42 COG4422 COG4422, Bacteriophage protein gp37 Function unknown 119714209 Common - response regulator receiver Noca_4906 162 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 119714211 Common - hypothetical protein Noca_4910 17 COG5486 COG5486, Predicted metal-binding integral membrane protein Function unknown 119714206 Nonpathogen - hypothetical protein Noca_4903 1 None None None 119714163 Common - hypothetical protein Noca_4860 14 COG2345 COG2345, Predicted transcriptional regulator Transcription 119714103 Nonpathogen - hypothetical protein Noca_4798 1 None None None 119714052 Nonpathogen - hypothetical protein Noca_4745 1 None None None 119714059 Nonpathogen - hypothetical protein Noca_4752 2 None None None 119714054 Common - helicase domain protein Noca_4747 37 COG4646 COG4646, DNA methylase Transcription / DNA replication, recombination, and repair 119714013 Common - Type IV secretory pathway VirD4 components-like protein Noca_4706 21 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 119714122 Nonpathogen - hypothetical protein Noca_4817 7 None None None 119714141 Common - 1-aminocyclopropane-1-carboxylate deaminase Noca_4836 64 COG2515 Acd, 1-aminocyclopropane-1-carboxylate deaminase Amino acid transport and metabolism 119714175 Common - Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) Noca_4872 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 119714177 Common - glycoside hydrolase 15-related Noca_4874 66 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 119714267 Nonpathogen - hypothetical protein Noca_4967 1 None None None 119714118 Common - coenzyme A transferase Noca_4813 88 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 119714086 Common - hypothetical protein Noca_4781 7 None None None 119714230 Common - short-chain dehydrogenase/reductase SDR Noca_4929 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119714060 Nonpathogen - hypothetical protein Noca_4753 1 None None None 119714225 Nonpathogen - hypothetical protein Noca_4924 1 None None None 119714125 Common - Argininosuccinate lyase Noca_4820 213 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 119714165 Common - hypothetical protein Noca_4862 26 COG4309 COG4309, Uncharacterized conserved protein Function unknown 119714170 Common - band 7 protein Noca_4867 207 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 119714136 Common - hypothetical protein Noca_4831 56 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 119714067 Common - SMC domain protein Noca_4760 34 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 119714094 Common - SMF family protein Noca_4789 197 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 119714181 Nonpathogen - hypothetical protein Noca_4878 2 COG3355 COG3355, Predicted transcriptional regulator Transcription 119714045 Common - protein of unknown function DUF1016 Noca_4738 49 COG4804 COG4804, Uncharacterized conserved protein Function unknown 119714147 Common - coenzyme A transferase Noca_4842 90 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 119714161 Common - hypothetical protein Noca_4857 6 None None None 119714043 Nonpathogen - hypothetical protein Noca_4736 1 None None None 119714050 Nonpathogen - hypothetical protein Noca_4743 2 None None None 119714151 Nonpathogen - hypothetical protein Noca_4847 1 None None None 119714057 Common - hypothetical protein Noca_4750 7 None None None 119714185 Nonpathogen - hypothetical protein Noca_4882 3 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 119714038 Nonpathogen - SAF domain Noca_4731 7 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 119714265 Nonpathogen - hypothetical protein Noca_4965 3 None None None 119714191 Common - bifunctional deaminase-reductase domain protein Noca_4888 56 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 119714158 Nonpathogen - hypothetical protein Noca_4854 1 None None None 119714143 Nonpathogen - hypothetical protein Noca_4838 4 None None None 119714078 Common - helicase domain protein Noca_4771 122 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 119714259 Nonpathogen - hypothetical protein Noca_4959 1 None None None 119714015 Nonpathogen - hypothetical protein Noca_4708 2 None None None 119714075 Nonpathogen - McrBC 5-methylcytosine restriction system component-like protein Noca_4768 8 COG4268 McrC, McrBC 5-methylcytosine restriction system component Defense mechanisms 119714223 Common - hypothetical protein Noca_4922 6 None None None 119714106 Common - molybdopterin oxidoreductase Noca_4801 169 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 119714270 Nonpathogen - hypothetical protein Noca_4970 3 None None None 119714084 Nonpathogen - hypothetical protein Noca_4777 2 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 119714179 Nonpathogen - hypothetical protein Noca_4876 3 None None None 119714204 Common - histidine kinase, dimerisation and phosphoacceptor region Noca_4901 61 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 119714232 Common - hypothetical protein Noca_4931 17 COG5486 COG5486, Predicted metal-binding integral membrane protein Function unknown 119714183 Nonpathogen - hypothetical protein Noca_4880 2 None None None 119714023 Nonpathogen - hypothetical protein Noca_4716 2 None None None 119714131 Common - short-chain dehydrogenase/reductase SDR Noca_4826 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119714261 Nonpathogen - hypothetical protein Noca_4961 1 None None None 119714010 Nonpathogen - hypothetical protein Noca_4703 2 None None None 119714138 Common - succinate-semialdehyde dehydrogenase (NAD(P)(+)) Noca_4833 114 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 119714111 Common - oxidoreductase FAD/NAD(P)-binding domain protein Noca_4806 170 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 119714127 Common - succinate-semialdehyde dehydrogenase (NAD(P)(+)) Noca_4822 122 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 119714146 Common - short-chain dehydrogenase/reductase SDR Noca_4841 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119714256 Nonpathogen - hypothetical protein Noca_4956 1 None None None 119714072 Nonpathogen - hypothetical protein Noca_4765 2 None None None 119714240 Nonpathogen - ABC-2 type transporter Noca_4940 3 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 119714263 Nonpathogen - hypothetical protein Noca_4963 1 None None None 119714017 Nonpathogen - hypothetical protein Noca_4710 1 None None None 119714252 Common - cytochrome c biogenesis protein, transmembrane region Noca_4952 10 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 119714055 Common - protein of unknown function DUF1173 Noca_4748 16 None None None 119714026 Common - Peptidoglycan-binding LysM Noca_4719 14 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 119714036 Common - type II secretion system protein E Noca_4729 167 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 119714172 Common - transaldolase Noca_4869 74 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 119714215 Common - protein of unknown function DUF1486 Noca_4914 26 COG5485 COG5485, Predicted ester cyclase General function prediction only 119714239 Common - ABC transporter related Noca_4939 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 119714221 Common - regulatory protein, LuxR Noca_4920 26 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 119714153 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Noca_4849 235 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 119714041 Nonpathogen - regulatory protein, ArsR Noca_4734 3 COG1777 COG1777, Predicted transcriptional regulators Transcription 119714097 Common - phage integrase family protein Noca_4792 156 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 119714049 Nonpathogen - hypothetical protein Noca_4742 2 None None None 119714066 Nonpathogen - hypothetical protein Noca_4759 2 None None None 119714217 Common - alpha/beta hydrolase fold Noca_4916 172 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 119714113 Nonpathogen - monooxygenase component MmoB/DmpM Noca_4808 1 None None None 119714090 Common - helicase domain protein Noca_4785 143 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 119714193 Nonpathogen - hypothetical protein Noca_4890 1 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 119714082 Nonpathogen - hypothetical protein Noca_4775 1 None None None 119714133 Nonpathogen - hypothetical protein Noca_4828 12 None None None 119714128 Common - hypothetical protein Noca_4823 53 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 119714202 Nonpathogen - hypothetical protein Noca_4899 1 None None None 119714237 Common - DNA primase catalytic core, N-terminal domain Noca_4936 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 119714174 Common - hypothetical protein Noca_4871 6 None None None 119714250 Common - regulatory protein, MerR Noca_4950 133 COG0789 SoxR, Predicted transcriptional regulators Transcription 119714019 Common - hypothetical protein Noca_4712 6 None None None 119714254 Common - regulatory protein, MerR Noca_4954 130 COG0789 SoxR, Predicted transcriptional regulators Transcription 119714246 Common - mercuric reductase Noca_4946 241 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 119714121 Common - Phosphosulfolactate synthase Noca_4816 22 COG1809 COG1809, Uncharacterized conserved protein Function unknown 119714012 Nonpathogen - hypothetical protein Noca_4705 2 None None None 119714096 Common - hypothetical protein Noca_4791 6 None None None 119714079 Common - DEAD/DEAH box helicase domain protein Noca_4772 136 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 119714168 Common - Cytochrome-c oxidase Noca_4865 164 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 119714155 Common - hypothetical protein Noca_4851 6 None None None 119714228 Nonpathogen - hypothetical protein Noca_4927 1 COG3832 COG3832, Uncharacterized conserved protein Function unknown 119714213 Common - helix-turn-helix, HxlR type Noca_4912 88 COG1733 COG1733, Predicted transcriptional regulators Transcription 119714034 Common - hypothetical protein Noca_4727 5 COG4134 COG4134, ABC-type uncharacterized transport system, periplasmic component General function prediction only 119714148 Common - glutaconate CoA-transferase Noca_4843 40 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 119714268 Common - helix-turn-helix domain protein Noca_4968 39 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 119714028 Nonpathogen - TadE family protein Noca_4721 6 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 119714242 Common - alkylmercury lyase Noca_4942 6 None None None 119714100 Nonpathogen - hypothetical protein Noca_4795 1 None None None 119714176 Nonpathogen - hypothetical protein Noca_4873 4 None None None 119714116 Common - CoA-binding domain protein Noca_4811 141 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 119714008 Nonpathogen - hypothetical protein Noca_4701 1 None None None 119714115 Common - Methionine synthase, vitamin-B12 independent Noca_4810 140 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 119714064 Nonpathogen - hypothetical protein Noca_4757 1 None None None 119714032 Common - phage integrase family protein Noca_4725 191 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 119714047 Nonpathogen - hypothetical protein Noca_4740 3 None None None 119714021 Nonpathogen - hypothetical protein Noca_4714 2 None None None 119714135 Common - Integrase, catalytic region Noca_4830 145 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 119714062 Nonpathogen - hypothetical protein Noca_4755 1 None None None 119714088 Nonpathogen - hypothetical protein Noca_4783 1 None None None 119714195 Common - transcriptional activator domain Noca_4892 27 COG3629 DnrI, DNA-binding transcriptional activator of the SARP family Signal transduction mechanisms 119714101 Nonpathogen - hypothetical protein Noca_4796 1 None None None 119714080 Nonpathogen - hypothetical protein Noca_4773 1 None None None 119714069 Nonpathogen - hypothetical protein Noca_4762 1 None None None 119714085 Common - helicase domain protein Noca_4780 27 None None None 119714231 Common - protein of unknown function DUF1326 Noca_4930 14 COG5588 COG5588, Uncharacterized conserved protein Function unknown 119714139 Common - phosphoadenosine phosphosulfate reductase Noca_4834 159 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 119714178 Nonpathogen - hypothetical protein Noca_4875 8 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 119714266 Common - MMPL domain protein Noca_4966 43 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 119714226 Common - protein of unknown function DUF1486 Noca_4925 30 COG5485 COG5485, Predicted ester cyclase General function prediction only 119714271 Nonpathogen - hypothetical protein Noca_4971 1 None None None 119714166 Common - ornithine aminotransferase Noca_4863 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 119714184 Nonpathogen - hypothetical protein Noca_4881 1 None None None 119714123 Common - fumarate lyase Noca_4818 223 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 119714150 Nonpathogen - hypothetical protein Noca_4846 1 None None None 119714197 Nonpathogen - hypothetical protein Noca_4894 1 None None None 119714046 Nonpathogen - hypothetical protein Noca_4739 2 None None None 119714102 Common - ParB domain protein nuclease Noca_4797 35 None None None 119714095 Nonpathogen - hypothetical protein Noca_4790 1 None None None 119714244 Nonpathogen - hypothetical protein Noca_4944 1 None None None 119714186 Common - hypothetical protein Noca_4883 22 None None None 119714207 Nonpathogen - hypothetical protein Noca_4904 1 None None None 119714200 Common - response regulator receiver Noca_4897 173 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 119714248 Common - Bile acid:sodium symporter Noca_4948 20 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 119714117 Common - glutaconate CoA-transferase Noca_4812 40 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 119714190 Nonpathogen - hypothetical protein Noca_4887 5 None None None 119714205 Common - response regulator receiver Noca_4902 219 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 119714105 Common - DNA primase catalytic core, N-terminal domain Noca_4800 214 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 119714039 Nonpathogen - hypothetical protein Noca_4732 4 None None None 119714210 Common - protein of unknown function DUF1326 Noca_4909 15 COG5588 COG5588, Uncharacterized conserved protein Function unknown 119714264 Common - hypothetical protein Noca_4964 2 None None None 119714199 Common - response regulator receiver Noca_4896 212 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 119714258 Common - protein of unknown function UPF0157 Noca_4958 28 COG2320 GrpB, Uncharacterized conserved protein Function unknown 119714104 Nonpathogen - hypothetical protein Noca_4799 1 None None None 119714030 Nonpathogen - hypothetical protein Noca_4723 1 None None None 119714051 Nonpathogen - hypothetical protein Noca_4744 2 None None None 119714076 Common - ATPase associated with various cellular activities, AAA_5 Noca_4769 50 COG1401 McrB, GTPase subunit of restriction endonuclease Defense mechanisms 119714053 Nonpathogen - hypothetical protein Noca_4746 2 None None None 119714142 Common - fumarate lyase Noca_4837 234 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 119714070 Nonpathogen - hypothetical protein Noca_4763 1 None None None 119714014 Nonpathogen - hypothetical protein Noca_4707 2 None None None 119714159 Common - hypothetical protein Noca_4855 6 None None None 119714009 Common - hypothetical protein Noca_4702 5 None None None 119714224 Nonpathogen - hypothetical protein Noca_4923 1 None None None 119714124 Common - 1-aminocyclopropane-1-carboxylate deaminase Noca_4819 62 COG2515 Acd, 1-aminocyclopropane-1-carboxylate deaminase Amino acid transport and metabolism 119714119 Common - short-chain dehydrogenase/reductase SDR Noca_4814 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119714130 Common - hypothetical protein Noca_4825 6 None None None 119714024 Nonpathogen - hypothetical protein Noca_4717 2 None None None 119714233 Common - bifunctional deaminase-reductase domain protein Noca_4932 42 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 119714068 Common - putative DNA helicase II / ATP-dependent DNA helicase PcrA Noca_4761 13 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 119714144 Common - Phosphosulfolactate synthase Noca_4839 22 COG1809 COG1809, Uncharacterized conserved protein Function unknown 119714229 Common - transcriptional activator domain Noca_4928 50 COG3899 COG3899, Predicted ATPase General function prediction only 119714188 Common - hypothetical protein Noca_4885 11 None None None 119714093 Common - putative Rossmann-fold nucleotide-binding protein Noca_4788 12 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 119714110 Nonpathogen - hypothetical protein Noca_4805 1 None None None 119714083 Common - C-5 cytosine-specific DNA methylase Noca_4776 28 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 119714192 Common - hypothetical protein Noca_4889 6 COG2044 COG2044, Predicted peroxiredoxins General function prediction only 119714044 Nonpathogen - hypothetical protein Noca_4737 2 None None None 119714092 Common - DEAD-like helicases-like protein Noca_4787 111 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 119714164 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Noca_4861 137 COG1146 COG1146, Ferredoxin Energy production and conversion 119714157 Common - sigma-24 (FecI-like) Noca_4853 4 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 119714037 Nonpathogen - hypothetical protein Noca_4730 5 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 119714152 Common - Patatin Noca_4848 137 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 119714260 Common - hypothetical protein Noca_4960 4 None None None 119714241 Nonpathogen - putative ABC-2 type transporter, permease protein Noca_4941 6 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 119714235 Nonpathogen - hypothetical protein Noca_4934 2 None None None 119714016 Common - hypothetical protein Noca_4709 10 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 119714077 Common - putative type II DNA modification enzyme Noca_4770 43 None None None 119714149 Common - CoA-binding domain protein Noca_4844 142 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 119714222 Nonpathogen - hypothetical protein Noca_4921 2 None None None 119714099 Nonpathogen - hypothetical protein Noca_4794 1 None None None 119714107 Nonpathogen - hypothetical protein Noca_4802 1 None None None 119714020 Common - hypothetical protein Noca_4713 5 COG1133 SbmA, ABC-type long-chain fatty acid transport system, fused permease and ATPase components Lipid metabolism 119714027 Nonpathogen - hypothetical protein Noca_4720 2 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 119714098 Common - phage integrase family protein Noca_4793 12 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 119714203 Nonpathogen - hypothetical protein Noca_4900 1 None None None 119714033 Common - hypothetical protein Noca_4726 8 COG3655 COG3655, Predicted transcriptional regulator Transcription 119714194 Nonpathogen - putative gualylate cyclase protein Noca_4891 4 None None None 119714065 Nonpathogen - hypothetical protein Noca_4758 3 None None None 119714112 Common - Methane monooxygenase Noca_4807 19 None None None 119714218 Common - putative hydrolase Noca_4917 11 COG2267 PldB, Lysophospholipase Lipid metabolism 119714089 Common - hypothetical protein Noca_4784 64 COG1201 Lhr, Lhr-like helicases General function prediction only 119714234 Nonpathogen - hypothetical protein Noca_4933 2 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 119714031 Nonpathogen - integral membrane protein Noca_4724 7 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 119714108 Nonpathogen - hypothetical protein Noca_4803 1 None None None 119714262 Common - transcriptional activator domain Noca_4962 40 COG3903 COG3903, Predicted ATPase General function prediction only 119714018 Nonpathogen - hypothetical protein Noca_4711 1 None None None 119714081 Nonpathogen - hypothetical protein Noca_4774 1 None None None 119714091 Common - transposase, IS4 family protein Noca_4786 6 None None None 119714129 Nonpathogen - hypothetical protein Noca_4824 12 None None None 119714132 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Noca_4827 247 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 119714169 Common - Sugar diacid utilization regulator-like protein Noca_4866 21 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 119714126 Common - phosphoadenosine phosphosulfate reductase Noca_4821 160 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 119714162 Common - 2-oxoacid dehydrogenase subunit E1 Noca_4858 134 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 119714243 Nonpathogen - hypothetical protein Noca_4943 1 None None None 119714154 Common - GTP cyclohydrolase I Noca_4850 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 119714058 Nonpathogen - hypothetical protein Noca_4751 1 None None None 119714087 Common - YfbU family protein Noca_4782 5 COG3013 COG3013, Uncharacterized conserved protein Function unknown 119714247 Common - regulatory protein, MerR Noca_4947 140 COG0789 SoxR, Predicted transcriptional regulators Transcription 119714257 Common - hypothetical protein Noca_4957 79 COG1742 COG1742, Uncharacterized conserved protein Function unknown 119714071 Nonpathogen - hypothetical protein Noca_4764 2 None None None 119714011 Common - Chromosomal replication initiator, DnaA C-terminal domain Noca_4704 5 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 119714220 Common - Methyltransferase type 11 Noca_4919 159 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 119714253 Common - hypothetical protein Noca_4953 2 None None None 119714025 Nonpathogen - hypothetical protein Noca_4718 2 None None None 119714171 Common - protein of unknown function DUF488 Noca_4868 76 COG3189 COG3189, Uncharacterized conserved protein Function unknown 119714214 Common - regulatory protein, LuxR Noca_4913 108 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 119714238 Common - regulatory protein, TetR Noca_4938 36 COG1309 AcrR, Transcriptional regulator Transcription 119714180 Nonpathogen - hypothetical protein Noca_4877 1 None None None 119714187 Common - hypothetical protein Noca_4884 6 None None None 119714042 Nonpathogen - hypothetical protein Noca_4735 2 None None None 119714035 Nonpathogen - integral membrane protein Noca_4728 7 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 119714216 Nonpathogen - hypothetical protein Noca_4915 1 None None None 119714063 Nonpathogen - hypothetical protein Noca_4756 1 None None None 119714114 Common - Methane monooxygenase Noca_4809 17 None None None 119714196 Common - Methyltransferase type 11 Noca_4893 115 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 119714022 Nonpathogen - hypothetical protein Noca_4715 2 None None None 119714040 Nonpathogen - hypothetical protein Noca_4733 2 None None None 119714029 Nonpathogen - hypothetical protein Noca_4722 3 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 119714137 Common - luciferase family protein Noca_4832 38 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 119714048 Common - Cobyrinic acid a,c-diamide synthase Noca_4741 157 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 119714201 Common - ATP-binding region, ATPase domain protein domain protein Noca_4898 138 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 119714120 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Noca_4815 243 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 119714109 Nonpathogen - hypothetical protein Noca_4804 1 None None None 119714182 Common - phage Gp37Gp68 family protein Noca_4879 42 COG4422 COG4422, Bacteriophage protein gp37 Function unknown 119714173 Common - UspA domain protein Noca_4870 11 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 119714236 Nonpathogen - hypothetical protein Noca_4935 1 None None None 119714134 Nonpathogen - hypothetical protein Noca_4829 5 None None None 119714061 Nonpathogen - hypothetical protein Noca_4754 1 None None None 119714140 Common - Argininosuccinate lyase Noca_4835 213 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 119714219 Common - metal-dependent phosphohydrolase, HD sub domain Noca_4918 157 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 119714255 Nonpathogen - hypothetical protein Noca_4955 1 None None None 119714251 Common - Redoxin domain protein Noca_4951 17 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 119714056 Nonpathogen - hypothetical protein Noca_4749 2 None None None 119714145 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Noca_4840 235 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 119714167 Common - alkylhydroperoxidase like protein, AhpD family Noca_4864 65 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 119714156 Common - hypothetical protein Noca_4852 17 COG2345 COG2345, Predicted transcriptional regulator Transcription 119714208 Common - ATP-binding region, ATPase domain protein domain protein Noca_4905 126 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 119714198 Common - histidine kinase, dimerisation and phosphoacceptor region Noca_4895 135 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 119714227 Common - regulatory protein, LuxR Noca_4926 114 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 119714245 Common - regulatory protein, MerR Noca_4945 97 COG0789 SoxR, Predicted transcriptional regulators Transcription 119714269 Nonpathogen - helicase, putative Noca_4969 3 None None None 119714212 Common - FAD linked oxidase domain protein Noca_4911 43 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 119714160 Common - Cupin 2, conserved barrel domain protein Noca_4856 10 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 119714189 Common - phage integrase family protein Noca_4886 12 None None None 119714249 Common - hypothetical protein Noca_4949 2 None None None 119714074 Common - hypothetical protein Noca_4767 6 None None None