Paracoccus denitrificans PD1222 chromosome 1, complete sequence NC_008686 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 119383621 Nonpathogen - hypothetical protein Pden_0870 1 None None None 119382776 Common - Carboxylesterase Pden_0019 93 COG0627 COG0627, Predicted esterase General function prediction only 119383713 Nonpathogen - hypothetical protein Pden_0962 2 None None None 119383732 Common - hypothetical protein Pden_0981 27 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 119382898 Nonpathogen - PilT protein-like Pden_0141 3 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 119384002 Common - ABC-3 protein Pden_1257 175 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 119382953 Common - 3-hydroxybutyryl-CoA dehydrogenase Pden_0197 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 119382954 Common - Butyryl-CoA dehydrogenase Pden_0198 166 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 119383201 Common - hypothetical protein Pden_0447 4 None None None 119384763 Common - Trans-hexaprenyltranstransferase Pden_2031 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 119384850 Nonpathogen - hypothetical protein Pden_2118 5 None None None 119385533 Common - NAD-dependent epimerase/dehydratase Pden_2809 98 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 119384099 Common - Methyltransferase type 11 Pden_1358 152 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 119384898 Common - General secretory system II, protein E domain protein Pden_2166 125 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 119384430 Common - major facilitator superfamily MFS_1 Pden_1693 142 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 119384846 Common flgF flagellar basal body rod protein FlgF Pden_2114 122 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 119383267 Common - sarcosine oxidase, alpha subunit family Pden_0515 181 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 119384296 Nonpathogen - hypothetical protein Pden_1556 4 None None None 119384339 Common - Glutathione S-transferase, N-terminal domain Pden_1599 16 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 119385321 Common infB translation initiation factor IF-2 Pden_2594 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 119383271 Common - protein of unknown function DUF461 Pden_0519 77 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 119383420 Common - transcriptional regulator, TetR family Pden_0668 32 COG1309 AcrR, Transcriptional regulator Transcription 119384609 Common - heat shock protein DnaJ domain protein Pden_1874 35 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 119383922 Common - Rieske (2Fe-2S) domain protein Pden_1177 81 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 119385086 Common - binding-protein-dependent transport systems inner membrane component Pden_2356 170 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 119383260 Nonpathogen - hypothetical protein Pden_0508 9 None None None 119384755 Common - Redoxin domain protein Pden_2023 168 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 119382978 Common - sigma54 specific transcriptional regulator, Fis family Pden_0224 166 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 119383484 Common - DNA-directed DNA polymerase Pden_0732 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 119384014 Common - hypothetical protein Pden_1269 24 COG4765 COG4765, Uncharacterized protein conserved in bacteria Function unknown 119384733 Common - protein of unknown function DUF55 Pden_2001 94 COG2947 COG2947, Uncharacterized conserved protein Function unknown 119383284 Common - UspA domain protein Pden_0532 26 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 119384652 Common pgk phosphoglycerate kinase Pden_1918 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 119385125 Nonpathogen - hypothetical protein Pden_2397 2 None None None 119384442 Common - hypothetical protein Pden_1705 5 None None None 119383007 Nonpathogen - hypothetical protein Pden_0253 1 None None None 119384602 Common - 2'-deoxycytidine 5'-triphosphate deaminase Pden_1865 27 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 119384423 Nonpathogen - hypothetical protein Pden_1686 11 COG5530 COG5530, Predicted integral membrane protein Function unknown 119385174 Common - protein of unknown function DUF879 Pden_2447 46 COG3519 COG3519, Uncharacterized protein conserved in bacteria Function unknown 119383838 Common - extracellular solute-binding protein, family 1 Pden_1090 58 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 119384267 Common - DEAD/DEAH box helicase domain protein Pden_1527 111 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 119384993 Common - TM2 domain containing protein+B7201 Pden_2261 12 COG2314 XynA, Predicted membrane protein Function unknown 119384635 Common - binding-protein-dependent transport systems inner membrane component Pden_1900 202 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 119384317 Common - hypothetical protein Pden_1577 15 None None None 119384754 Common - argininosuccinate lyase Pden_2022 234 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 119383763 Common - AMP-dependent synthetase and ligase Pden_1012 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 119385230 Common - L-asparaginase II Pden_2503 46 COG4448 AnsA, L-asparaginase II Amino acid transport and metabolism 119384047 Common - polyphosphate kinase Pden_1302 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 119384625 Common - ribonuclease D Pden_1890 118 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 119384724 Common - major facilitator superfamily MFS_1 Pden_1992 182 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 119384437 Common - Ribulose-bisphosphate carboxylase Pden_1700 29 COG4451 RbcS, Ribulose bisphosphate carboxylase small subunit Energy production and conversion 119384068 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Pden_1323 16 COG0748 HugZ, Putative heme iron utilization protein Inorganic ion transport and metabolism 119384683 Common - 6-phosphogluconolactonase Pden_1951 113 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 119384673 Common - FAD dependent oxidoreductase Pden_1940 177 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 119383467 Common - urocanate hydratase Pden_0715 97 COG2987 HutU, Urocanate hydratase Amino acid transport and metabolism 119383065 Common - integral membrane sensor signal transduction histidine kinase Pden_0311 97 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 119385165 Common - 3-oxoacyl-(acyl carrier protein) synthase Pden_2438 9 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 119383786 Common - transcriptional regulator, LysR family Pden_1035 170 COG0583 LysR, Transcriptional regulator Transcription 119385464 Common - LrgB family protein Pden_2740 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 119385114 Common - short-chain dehydrogenase/reductase SDR Pden_2384 234 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119384224 Common - type II secretion system protein E Pden_1484 111 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 119383842 Nonpathogen - hypothetical protein Pden_1094 3 None None None 119385007 Nonpathogen - hypothetical protein Pden_2275 1 None None None 119384415 Common - Inositol 2-dehydrogenase Pden_1678 166 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 119384210 Common - Lysine exporter protein (LYSE/YGGA) Pden_1470 122 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 119385415 Common - inositol monophosphatase Pden_2688 182 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 119383560 Nonpathogen - hypothetical protein Pden_0808 1 None None None 119384208 Common - protein of unknown function DUF1234 Pden_1468 51 COG3545 COG3545, Predicted esterase of the alpha/beta hydrolase fold General function prediction only 119383758 Common - transposase orfA IS5 family element Pden_1007 69 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 119382932 Common - inner-membrane translocator Pden_0176 99 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 119383583 Common - binding-protein-dependent transport systems inner membrane component Pden_0831 40 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 119382761 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA Pden_0004 192 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 119385457 Common - hypothetical protein Pden_2733 28 None None None 119384291 Common - protein of unknown function DUF481 Pden_1551 7 COG3137 COG3137, Putative salt-induced outer membrane protein Cell envelope biogenesis, outer membrane 119383047 Nonpathogen - hypothetical protein Pden_0293 1 None None None 119383218 Common - ABC transporter related Pden_0466 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 119384134 Nonpathogen - hypothetical protein Pden_1393 1 None None None 119383105 Nonpathogen - hypothetical protein Pden_0351 1 None None None 119385257 Common - protein of unknown function DUF1636 Pden_2530 16 COG5469 COG5469, Predicted metal-binding protein Function unknown 119384915 Common aspS aspartyl-tRNA synthetase Pden_2183 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 119383094 Common - hypothetical protein Pden_0340 2 None None None 119383958 Nonpathogen - hypothetical protein Pden_1213 1 None None None 119384823 Common - hypothetical protein Pden_2091 3 None None None 119385379 Common fliP flagellar biosynthesis protein FliP Pden_2652 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 119385268 Common - cobyrinic acid a,c-diamide synthase Pden_2541 136 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 119384858 Common - Capsule polysaccharide export protein-like Pden_2126 36 COG3524 KpsE, Capsule polysaccharide export protein Cell envelope biogenesis, outer membrane 119384900 Common - arginyl-tRNA-protein transferase Pden_2168 85 COG2935 COG2935, Putative arginyl-tRNA:protein arginylyltransferase Posttranslational modification, protein turnover, chaperones 119383014 Nonpathogen - hypothetical protein Pden_0260 1 None None None 119385328 Common - transcriptional regulator, MarR family Pden_2601 37 COG1846 MarR, Transcriptional regulators Transcription 119384357 Common - flagellar protein, putative Pden_1618 17 None None None 119385146 Nonpathogen - phage integrase family protein Pden_2418 5 None None None 119385096 Common - Aldehyde dehydrogenase (NAD(+)) Pden_2366 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 119384119 Common - hypothetical protein Pden_1378 21 None None None 119385444 Common - Fmu (Sun) domain protein Pden_2720 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 119383544 Common - ATP12 ATPase Pden_0792 33 COG5387 COG5387, Chaperone required for the assembly of the mitochondrial F1-ATPase Posttranslational modification, protein turnover, chaperones 119383852 Common - 4-vinyl reductase, 4VR Pden_1104 10 None None None 119384125 Common - ribonucleotide-diphosphate reductase subunit alpha Pden_1384 156 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 119384402 Common - putative transcriptional regulator, AsnC family Pden_1665 156 COG1522 Lrp, Transcriptional regulators Transcription 119383492 Nonpathogen - hypothetical protein Pden_0740 5 None None None 119384819 Common - hypothetical protein Pden_2087 22 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 119383132 Nonpathogen - hypothetical protein Pden_0378 1 None None None 119384982 Common - NADH dehydrogenase subunit A Pden_2250 162 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 119383505 Common rpsL 30S ribosomal protein S12 Pden_0753 236 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 119384667 Nonpathogen - translation initiation factor 2, gamma subunit, GTPase Pden_1934 10 None None None 119384082 Common - hypothetical protein Pden_1337 15 COG4875 COG4875, Uncharacterized protein conserved in bacteria with a cystatin-like fold Function unknown 119384191 Common - alpha/beta hydrolase Pden_1450 10 COG4757 COG4757, Predicted alpha/beta hydrolase General function prediction only 119384573 Common - DNA topoisomerase IV subunit B Pden_1836 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 119385388 Common - beta-lactamase Pden_2661 99 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 119385284 Common - hypothetical protein Pden_2557 19 None None None 119383965 Nonpathogen - hypothetical protein Pden_1220 1 None None None 119383333 Common - putative Mrp (multidrug resistance-associated proteins) family protein Pden_0581 233 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 119384791 Common - transposase orfA IS5 family element Pden_2059 69 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 119383805 Common - hypothetical protein Pden_1056 42 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 119383925 Common benD 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase Pden_1180 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119384514 Common - Citrate transporter Pden_1777 176 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 119384649 Common - protein of unknown function DUF188 Pden_1915 92 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 119384708 Nonpathogen - hypothetical protein Pden_1976 1 None None None 119385074 Common - putative transcriptional regulator, MerR family Pden_2343 143 COG0789 SoxR, Predicted transcriptional regulators Transcription 119382792 Common - transcriptional activator, TenA family Pden_0035 76 COG0819 TenA, Putative transcription activator Transcription 119385056 Common - Redoxin domain protein Pden_2325 81 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 119382938 Common - beta-lactamase-like protein Pden_0182 56 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 119383074 Common - LamB/YcsF family protein Pden_0320 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 119382783 Common - hypothetical protein Pden_0026 19 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 119383648 Common ksgA dimethyladenosine transferase Pden_0897 243 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 119384252 Common - replication protein A Pden_1512 32 COG5534 COG5534, Plasmid replication initiator protein DNA replication, recombination, and repair 119383205 Common - hypothetical protein Pden_0451 19 COG3600 GepA, Uncharacterized phage-associated protein Function unknown 119385552 Common - formate dehydrogenase, beta subunit Pden_2828 160 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 119384171 Nonpathogen - hypothetical protein Pden_1430 1 None None None 119384550 Common - Indigoidine synthase A family protein Pden_1813 49 COG2313 IndA, Uncharacterized enzyme involved in pigment biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 119383403 Common - putative transcriptional regulator, AsnC family Pden_0651 26 COG1522 Lrp, Transcriptional regulators Transcription 119384332 Common - peptidase M19, renal dipeptidase Pden_1592 102 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 119384943 Common - protein of unknown function DUF152 Pden_2211 182 COG1496 COG1496, Uncharacterized conserved protein Function unknown 119384458 Common - Dicarboxylate carrier MatC domain protein Pden_1721 19 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 119385478 Common - short-chain dehydrogenase/reductase SDR Pden_2754 187 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 119383245 Common - glucose-methanol-choline oxidoreductase Pden_0493 71 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 119383666 Nonpathogen - Entericidin EcnAB Pden_0915 1 COG5510 COG5510, Predicted small secreted protein Function unknown 119383438 Common tolB translocation protein TolB Pden_0686 168 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 119383997 Common - ABC transporter related Pden_1252 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 119383597 Common - ATPases involved in chromosome partitioning-like Pden_0845 36 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 119384909 Nonpathogen - protein of unknown function DUF1467 Pden_2177 1 COG5454 COG5454, Predicted secreted protein Function unknown 119385271 Nonpathogen - cytochrome c, class II Pden_2544 3 COG3909 COG3909, Cytochrome c556 Energy production and conversion 119383382 Common - aromatic amino acid aminotransferase Pden_0630 71 COG1448 TyrB, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 119383757 Common - transposase, IS4 family protein Pden_1006 53 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 119383639 Nonpathogen - hypothetical protein Pden_0888 1 None None None 119383087 Common trpA tryptophan synthase subunit alpha Pden_0333 210 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 119383413 Common - protein of unknown function DUF488 Pden_0661 77 COG3189 COG3189, Uncharacterized conserved protein Function unknown 119383116 Common - phage major capsid protein, HK97 family Pden_0362 17 COG4653 COG4653, Predicted phage phi-C31 gp36 major capsid-like protein General function prediction only 119384567 Nonpathogen - Sterol-binding domain protein Pden_1830 9 COG3255 COG3255, Putative sterol carrier protein Lipid metabolism 119384078 Common - cobalamin synthesis protein, P47K Pden_1333 122 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 119382850 Common - polysaccharide biosynthesis protein CapD Pden_0093 191 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 119384770 Nonpathogen - hypothetical protein Pden_2038 1 None None None 119382859 Common - phage transcriptional regulator, AlpA Pden_0102 41 COG3311 AlpA, Predicted transcriptional regulator Transcription 119382764 Common - parB-like partition proteins Pden_0007 186 COG1475 Spo0J, Predicted transcriptional regulators Transcription 119383304 Common - inner membrane protein Pden_0552 25 COG3686 COG3686, Predicted membrane protein Function unknown 119382902 Common - transcriptional regulator, CopG family Pden_0145 8 COG3905 COG3905, Predicted transcriptional regulator Transcription 119383874 Common - hypothetical protein Pden_1126 42 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 119385156 Common - seryl-tRNA synthetase Pden_2429 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 119383155 Common - SH3, type 3 domain protein Pden_0401 5 COG3650 COG3650, Predicted membrane protein Function unknown 119382973 Common - hypothetical protein Pden_0219 7 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 119385079 Common - short-chain dehydrogenase/reductase SDR Pden_2349 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119383526 Common rplF 50S ribosomal protein L6 Pden_0774 238 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 119384492 Common - methyltransferase small Pden_1755 56 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 119384142 Common - DNA-directed RNA polymerase subunit omega Pden_1401 112 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 119384112 Nonpathogen - hypothetical protein Pden_1371 1 None None None 119383141 Nonpathogen - hypothetical protein Pden_0387 1 None None None 119384925 Common - peptidase M24 Pden_2193 231 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 119384615 Common - hypothetical protein Pden_1880 55 COG2862 COG2862, Predicted membrane protein Function unknown 119383325 Common - hypothetical protein Pden_0573 40 COG3665 COG3665, Uncharacterized conserved protein Function unknown 119383691 Common - transcriptional regulator, LysR family Pden_0940 145 COG0583 LysR, Transcriptional regulator Transcription 119383891 Common - ABC transporter related Pden_1143 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 119384539 Nonpathogen - hypothetical protein Pden_1802 3 None None None 119385431 Common - Leucyl aminopeptidase Pden_2707 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 119383361 Common - ABC transporter related Pden_0609 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 119383458 Common - protein of unknown function DUF6, transmembrane Pden_0706 91 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 119383975 Nonpathogen - hypothetical protein Pden_1230 1 None None None 119384935 Nonpathogen - protein of unknown function DUF465 Pden_2203 8 COG5481 COG5481, Uncharacterized conserved small protein containing a coiled-coil domain Function unknown 119383664 Common - homogentisate 1,2-dioxygenase Pden_0913 49 COG3508 HmgA, Homogentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 119384242 Common - hypothetical protein Pden_1502 17 None None None 119384872 Common - molybdenum cofactor biosynthesis protein C Pden_2140 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 119383349 Common recA recombinase A Pden_0597 214 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 119384036 Nonpathogen - hypothetical protein Pden_1291 1 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 119385500 Common - hypothetical protein Pden_2776 25 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 119385213 Common - FMN-binding domain protein Pden_2486 64 COG3901 NosR, Regulator of nitric oxide reductase transcription Transcription 119384828 Common - protein of unknown function DUF1159 Pden_2096 22 COG5389 COG5389, Uncharacterized protein conserved in bacteria Function unknown 119383341 Common - UDP-N-acetylmuramoylalanine--D-glutamate ligase Pden_0589 210 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 119383581 Common - extracellular solute-binding protein, family 1 Pden_0829 67 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 119383687 Common - transcriptional regulator, MarR family Pden_0936 22 COG1846 MarR, Transcriptional regulators Transcription 119382949 Common - TRAP dicarboxylate transporter- DctP subunit Pden_0193 86 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 119384148 Nonpathogen - hypothetical protein Pden_1407 2 COG4093 COG4093, Uncharacterized protein conserved in bacteria Function unknown 119382835 Common - truncated transposase Pden_0078 55 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 119383867 Common - NADPH-dependent F420 reductase Pden_1119 35 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 119383882 Common - short-chain dehydrogenase/reductase SDR Pden_1134 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119384742 Common - MiaB-like tRNA modifying enzyme YliG Pden_2010 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 119385212 Common - ApbE family lipoprotein Pden_2485 28 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 119385246 Nonpathogen - hypothetical protein Pden_2519 1 None None None 119383350 Common alaS alanyl-tRNA synthetase Pden_0598 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 119384856 Common - Hemolysin-type calcium-binding region Pden_2124 119 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 119383009 Nonpathogen - hypothetical protein Pden_0255 2 None None None 119384100 Common - pseudoazurin Pden_1359 25 COG3794 PetE, Plastocyanin Energy production and conversion 119384488 Common - Phosphoglycerate mutase Pden_1751 147 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 119383441 Common - tRNA(Ile)-lysidine synthetase Pden_0689 192 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 119383776 Common - extracellular solute-binding protein, family 3 Pden_1025 170 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 119382895 Nonpathogen - hypothetical protein Pden_0138 2 None None None 119384579 Common - heavy metal translocating P-type ATPase Pden_1842 231 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 119383962 Common - hypothetical protein Pden_1217 13 COG4430 COG4430, Uncharacterized protein conserved in bacteria Function unknown 119384923 Common - cobalt chelatase, pCobT subunit Pden_2191 41 COG4547 CobT, Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase) Coenzyme metabolism 119384159 Common mazG nucleoside triphosphate pyrophosphohydrolase Pden_1418 155 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 119385428 Common - transposase and inactivated derivative Pden_2704 72 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 119385480 Common - Peroxidase Pden_2756 211 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 119383296 Common - dihydropteroate synthase Pden_0544 216 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 119384137 Common - glutamine amidotransferase class-I Pden_1396 162 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 119385060 Common - YceI family protein Pden_2329 94 COG2353 COG2353, Uncharacterized conserved protein Function unknown 119385233 Common - phosphoglyceromutase Pden_2506 126 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 119383368 Common - bacterioferritin Pden_0616 110 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 119384127 Common - magnesium transporter Pden_1386 170 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 119385182 Common - Rhs element Vgr protein Pden_2455 54 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 119385446 Common - transporter, hydrophobe/amphiphile efflux-1 (HAE1) family Pden_2722 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 119384025 Nonpathogen - hypothetical protein Pden_1280 6 None None None 119384984 Common uvrA excinuclease ABC subunit A Pden_2252 237 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 119384110 Nonpathogen - hypothetical protein Pden_1369 1 None None None 119383858 Common - protein of unknown function DUF1330 Pden_1110 44 COG5470 COG5470, Uncharacterized conserved protein Function unknown 119384570 Common - peptidase M19, renal dipeptidase Pden_1833 98 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 119384150 Common - histidinol-phosphate aminotransferase Pden_1409 230 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 119384532 Common - Allergen V5/Tpx-1 family protein Pden_1795 120 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 119383819 Common - regulatory proteins, IclR Pden_1070 110 COG1414 IclR, Transcriptional regulator Transcription 119385542 Common - Lysine exporter protein (LYSE/YGGA) Pden_2818 93 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 119383474 Nonpathogen - hypothetical protein Pden_0722 1 None None None 119384787 Nonpathogen - hypothetical protein Pden_2055 1 None None None 119383391 Common - protein of unknown function DUF463, YcjX family protein Pden_0639 42 COG3106 COG3106, Predicted ATPase General function prediction only 119382819 Common - ATPase AAA-2 domain protein Pden_0062 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 119383828 Common - binding-protein-dependent transport systems inner membrane component Pden_1079 189 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 119384107 Nonpathogen - hypothetical protein Pden_1366 3 None None None 119385367 Nonpathogen - hypothetical protein Pden_2640 1 None None None 119383931 Common - Alcohol dehydrogenase GroES domain protein Pden_1186 185 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 119385048 Common - protein of unknown function DUF140 Pden_2317 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 119384808 Nonpathogen - RNA polymerase, sigma-24 subunit, ECF subfamily Pden_2076 2 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 119383387 Common - NUDIX hydrolase Pden_0635 30 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 119385309 Nonpathogen - hypothetical protein Pden_2582 1 None None None 119385479 Common - aldehyde dehydrogenase Pden_2755 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 119385507 Common - metal dependent phosphohydrolase Pden_2783 32 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 119385204 Common - N-acetylglucosamine-6-phosphate deacetylase Pden_2477 118 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 119383994 Common - binding-protein-dependent transport systems inner membrane component Pden_1249 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 119384834 Common - Ribonuclease H Pden_2102 221 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 119384089 Common - ABC transporter related Pden_1344 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 119385523 Common rbfA ribosome-binding factor A Pden_2799 46 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 119383938 Common - glycine betaine/L-proline ABC transporter, ATPase subunit Pden_1193 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 119384876 Common - dTMP kinase Pden_2144 230 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 119383572 Common - anti-sigma-factor antagonist Pden_0820 38 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 119383916 Common - TonB-dependent receptor Pden_1171 120 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 119383579 Common - DNA mismatch repair protein Pden_0827 200 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 119383563 Common - Phosphatidylcholine synthase Pden_0811 23 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 119384729 Nonpathogen - putative uroporphyrinogen-III synthase Pden_1997 8 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 119385402 Common - secretion protein HlyD family protein Pden_2675 101 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 119383191 Common - hypothetical protein Pden_0437 60 COG4233 COG4233, Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis Posttranslational modification, protein turnover, chaperones / Energy production and conversion 119382882 Nonpathogen - hypothetical protein Pden_0125 1 None None None 119384244 Nonpathogen - hypothetical protein Pden_1504 1 None None None 119384080 Common - riboflavin biosynthesis protein RibD Pden_1335 201 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 119382987 Common - membrane protein-like Pden_0233 10 COG1289 COG1289, Predicted membrane protein Function unknown 119383671 Common - Glycine hydroxymethyltransferase Pden_0920 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 119383240 Common - Glutamate synthase (ferredoxin) Pden_0488 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 119383606 Common - MORN repeat-containing protein Pden_0854 33 COG4642 COG4642, Uncharacterized protein conserved in bacteria Function unknown 119383371 Common - D-fructose-6-phosphate amidotransferase Pden_0619 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 119384509 Common - beta-lactamase domain protein Pden_1772 158 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 119383678 Common - putative deoxyguanosinetriphosphate triphosphohydrolase Pden_0927 160 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 119383946 Common - hypothetical protein Pden_1201 7 None None None 119385252 Common - cobalt transporter, subunit CbtA Pden_2525 16 COG5446 COG5446, Predicted integral membrane protein Function unknown 119382808 Common - inner-membrane translocator Pden_0051 151 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 119384666 Common - O-acetylhomoserine/O-acetylserine sulfhydrylase Pden_1933 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 119385069 Common - 4-aminobutyrate aminotransferase Pden_2338 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 119384607 Common - arginyl-tRNA synthetase Pden_1870 247 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 119384951 Common - uracil phosphoribosyltransferase Pden_2219 165 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 119384519 Common - cation/multidrug efflux pump, RND family Pden_1782 173 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 119385255 Common - hypothetical protein Pden_2528 13 COG5649 COG5649, Uncharacterized conserved protein Function unknown 119382827 Common - hypothetical protein Pden_0070 36 COG2954 COG2954, Uncharacterized protein conserved in bacteria Function unknown 119383586 Common - glycosyl transferase, WecB/TagA/CpsF family Pden_0834 108 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 119383056 Common - transcriptional regulator, LysR family Pden_0302 184 COG0583 LysR, Transcriptional regulator Transcription 119382799 Common - phosphomethylpyrimidine kinase Pden_0042 218 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 119384585 Common - cytochrome c oxidase, cbb3-type, subunit I Pden_1848 137 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 119383512 Common rplD 50S ribosomal protein L4 Pden_0760 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 119384504 Common - Ferritin, Dps family protein Pden_1767 70 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 119384540 Common - glycosyl transferase, group 1 Pden_1803 88 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 119383024 Common - gene transfer agent (GTA) like protein Pden_0270 28 None None None 119382864 Nonpathogen - hypothetical protein Pden_0107 1 None None None 119384547 Nonpathogen - hypothetical protein Pden_1810 6 None None None 119385003 Common - arsenate reductase Pden_2271 96 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 119382843 Nonpathogen - hypothetical protein Pden_0086 1 None None None 119383396 Common - hypothetical protein Pden_0644 16 COG4425 COG4425, Predicted membrane protein Function unknown 119383356 Nonpathogen - hypothetical protein Pden_0604 6 None None None 119384279 Common - hypothetical protein Pden_1539 4 None None None 119383745 Nonpathogen - hypothetical protein Pden_0994 1 None None None 119383554 Common - binding-protein-dependent transport systems inner membrane component Pden_0802 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 119384120 Nonpathogen - hypothetical protein Pden_1379 1 None None None 119385206 Nonpathogen - hypothetical protein Pden_2479 1 None None None 119385020 Common - Glutathione S-transferase, N-terminal domain Pden_2289 116 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 119383905 Common - hypothetical protein Pden_1158 23 COG2014 COG2014, Uncharacterized conserved protein Function unknown 119384009 Common - peptidyl-tRNA hydrolase Pden_1264 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 119383986 Common - UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase Pden_1241 144 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 119382806 Common - ABC transporter related Pden_0049 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 119383634 Common - protein of unknown function DUF1025 Pden_0883 25 COG3824 COG3824, Uncharacterized protein conserved in bacteria Function unknown 119383761 Common - sulfoacetaldehyde acetyltransferase Pden_1010 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 119383792 Common - aspartate dehydrogenase Pden_1041 48 COG1712 COG1712, Predicted dinucleotide-utilizing enzyme General function prediction only 119384271 Common - hypothetical protein Pden_1531 20 None None None 119384869 Common - anthranilate phosphoribosyltransferase Pden_2137 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 119382982 Nonpathogen - Xylose isomerase domain protein TIM barrel Pden_0228 2 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 119383127 Common - hypothetical protein Pden_0373 3 None None None 119383903 Nonpathogen - hypothetical protein Pden_1155 1 None None None 119384381 Common - protein of unknown function DUF1486 Pden_1644 15 COG4319 COG4319, Ketosteroid isomerase homolog Function unknown 119384453 Common - ABC transporter related Pden_1716 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 119383172 Common era GTP-binding protein Era Pden_0418 225 COG1159 Era, GTPase General function prediction only 119383194 Common - 3-isopropylmalate dehydrogenase Pden_0440 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 119382901 Common - plasmid stabilization system Pden_0144 10 COG3668 ParE, Plasmid stabilization system protein General function prediction only 119385510 Common - import inner membrane translocase, subunit Tim44 Pden_2786 42 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 119383610 Common - Pyridoxamine-phosphate oxidase Pden_0858 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 119383760 Common - conserved hypothetical protein 698 Pden_1009 114 COG2855 COG2855, Predicted membrane protein Function unknown 119382967 Common - Putative protein-S-isoprenylcysteine methyltransferase-like Pden_0213 22 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 119383879 Common - hypothetical protein Pden_1131 13 None None None 119385391 Common - putative transcriptional regulator, ModE family Pden_2664 93 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 119383701 Common - peptidase S8 and S53, subtilisin, kexin, sedolisin Pden_0950 116 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 119384432 Common - Inositol phosphatase/fructose-1,6-bisphosphatase Pden_1695 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 119384703 Common - hypothetical protein Pden_1971 15 None None None 119385342 Common - Patatin Pden_2615 14 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 119382875 Common - hypothetical protein Pden_0118 25 COG4898 COG4898, Uncharacterized protein conserved in bacteria Function unknown 119383373 Common - peptide methionine sulfoxide reductase Pden_0621 204 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 119385019 Common - monofunctional biosynthetic peptidoglycan transglycosylase Pden_2288 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 119384325 Common - two component transcriptional regulator, winged helix family Pden_1585 207 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 119383224 Common - 5-oxoprolinase (ATP-hydrolyzing) Pden_0472 119 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 119384962 Common - biotin--acetyl-CoA-carboxylase ligase Pden_2230 204 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 119383256 Common - inner-membrane translocator Pden_0504 126 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 119384187 Common - major facilitator superfamily MFS_1 Pden_1446 69 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 119383831 Nonpathogen - hypothetical protein Pden_1082 1 None None None 119384810 Common - hypothetical protein Pden_2078 6 None None None 119385352 Nonpathogen - hypothetical protein Pden_2625 1 None None None 119384063 Common nadD nicotinic acid mononucleotide adenyltransferase Pden_1318 165 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 119384337 Common - periplasmic solute binding protein Pden_1597 165 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 119385293 Common - hypothetical protein Pden_2566 48 COG3391 COG3391, Uncharacterized conserved protein Function unknown 119384344 Common - Transketolase, central region Pden_1604 166 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 119385084 Common - two component transcriptional regulator, LuxR family Pden_2354 165 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 119384303 Common - TRAP dicarboxylate transporter- DctP subunit Pden_1563 77 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 119385489 Common leuS leucyl-tRNA synthetase Pden_2765 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 119383217 Common - transposase IS116/IS110/IS902 family protein Pden_0464 75 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 119384163 Common - transcriptional regulator, BadM/Rrf2 family Pden_1422 47 COG1959 COG1959, Predicted transcriptional regulator Transcription 119384714 Nonpathogen - hypothetical protein Pden_1982 1 None None None 119384364 Nonpathogen - hypothetical protein Pden_1626 1 None None None 119385518 Common - UvrD-like DNA helicase, C-terminal domain Pden_2794 225 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 119383614 Common - PTSINtr with GAF domain, PtsP Pden_0863 235 COG3605 PtsP, Signal transduction protein containing GAF and PtsI domains Signal transduction mechanisms 119384974 Nonpathogen - hypothetical protein Pden_2242 4 None None None 119384537 Common - sulfate ABC transporter, inner membrane subunit CysW Pden_1800 167 COG4208 CysW, ABC-type sulfate transport system, permease component Inorganic ion transport and metabolism 119384160 Nonpathogen - hypothetical protein Pden_1419 1 COG3178 COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases General function prediction only 119384658 Common hisZ ATP phosphoribosyltransferase regulatory subunit Pden_1924 88 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 119385135 Common - Mur ligase, middle domain protein Pden_2407 207 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 119384439 Common - PimS2 protein Pden_1702 6 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 119384671 Common - Cytochrome-c oxidase Pden_1938 169 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 119384530 Common - protein of unknown function DUF329 Pden_1793 49 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 119383192 Common - phage SPO1 DNA polymerase-related protein Pden_0438 151 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 119385046 Common - Mammalian cell entry related domain protein Pden_2315 73 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 119383130 Common - hypothetical protein Pden_0376 9 COG4733 COG4733, Phage-related protein, tail component Function unknown 119383011 Common - hypothetical protein Pden_0257 7 None None None 119383844 Common - glycoside hydrolase, family 3 domain protein Pden_1096 162 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 119383385 Common - acetolactate synthase 2 catalytic subunit Pden_0633 220 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 119383747 Common - gene transfer agent Pden_0996 6 None None None 119384600 Common - integration host factor, alpha subunit Pden_1863 198 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 119385289 Common - hypothetical protein Pden_2562 30 None None None 162139377 Common - preprotein translocase subunit SecA Pden_2599 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 119382995 Common - (R)-2-hydroxyacid dehydrogenase Pden_0241 67 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 119385104 Common - two component transcriptional regulator, winged helix family Pden_2374 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 119384238 Common - major facilitator superfamily MFS_1 Pden_1498 67 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 119384516 Common - Uncharacterized conserved protein UCP032025 Pden_1779 31 COG5458 COG5458, Uncharacterized conserved protein Function unknown 119383823 Common - polar amino acid ABC transporter, inner membrane subunit Pden_1074 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 119383005 Common - PfkB domain protein Pden_0251 121 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 119384374 Common - isochorismatase hydrolase Pden_1636 53 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 119385111 Common - diacylglycerol kinase, catalytic region Pden_2381 23 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 119385027 Common - UDP-glucose 4-epimerase Pden_2296 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 119382971 Common - regulatory protein, ArsR Pden_0217 69 COG0640 ArsR, Predicted transcriptional regulators Transcription 119385394 Common - molybdate ABC transporter, ATPase subunit Pden_2667 249 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 119384695 Common - plasmid maintenance system antidote protein, XRE family Pden_1963 60 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 119385501 Common - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase Pden_2777 41 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 119384136 Common - aminotransferase, class V Pden_1395 127 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 119384736 Common - hypothetical protein Pden_2004 51 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 119383552 Common - ABC transporter related Pden_0800 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 119384796 Common - phage terminase, small subunit, putative, P27 family Pden_2064 16 COG3747 COG3747, Phage terminase, small subunit DNA replication, recombination, and repair 119383796 Common - proline racemase Pden_1045 47 COG3938 COG3938, Proline racemase Amino acid transport and metabolism 119383273 Common - heavy metal translocating P-type ATPase Pden_0521 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 119383486 Common - elongation factor Tu Pden_0734 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 119384769 Common - type I secretion membrane fusion protein, HlyD family Pden_2037 106 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 119384256 Common - hypothetical protein Pden_1516 13 None None None 119384413 Common - PfkB domain protein Pden_1676 137 COG3892 COG3892, Uncharacterized protein conserved in bacteria Function unknown 119384394 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase Pden_1657 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 119384913 Common - protein of unknown function DUF1501 Pden_2181 34 COG4102 COG4102, Uncharacterized protein conserved in bacteria Function unknown 119383299 Common - transcriptional regulator, TraR/DksA family Pden_0547 153 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 119384206 Common - helix-turn-helix- domain containing protein, AraC type Pden_1466 20 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 119383054 Common - periplasmic binding protein Pden_0300 81 COG4607 CeuA, ABC-type enterochelin transport system, periplasmic component Inorganic ion transport and metabolism 119384920 Common - protein of unknown function DUF808 Pden_2188 60 COG2354 COG2354, Uncharacterized protein conserved in bacteria Function unknown 119382951 Common - L-carnitine dehydratase/bile acid-inducible protein F Pden_0195 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 119383739 Common - phage Terminase Pden_0988 40 COG4626 COG4626, Phage terminase-like protein, large subunit General function prediction only 119383018 Common - hypothetical protein Pden_0264 38 COG4680 COG4680, Uncharacterized protein conserved in bacteria Function unknown 119383031 Common - ChaC family protein Pden_0277 40 COG3703 ChaC, Uncharacterized protein involved in cation transport Inorganic ion transport and metabolism 119383203 Common - Exonuclease, RNase T and DNA polymerase III Pden_0449 23 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 119383041 Common - peptidase M24 Pden_0287 176 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 119384180 Common - hypothetical protein Pden_1439 44 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 119384212 Common - Methyltransferase type 12 Pden_1472 65 COG4976 COG4976, Predicted methyltransferase (contains TPR repeat) General function prediction only 119382958 Common - 3,4-dihydroxy-2-butanone 4-phosphate synthase Pden_0204 225 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 119384283 Common - hypothetical protein Pden_1543 19 None None None 119385450 Common - protein-L-isoaspartate(D-aspartate) O-methyltransferase Pden_2726 151 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 119383328 Common gatA aspartyl/glutamyl-tRNA amidotransferase subunit A Pden_0576 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 119383460 Common - UbiC transcription regulator-associated domain protein Pden_0708 123 COG2188 PhnF, Transcriptional regulators Transcription 119385183 Common - protein of unknown function DUF1215 Pden_2456 10 COG3523 IcmF, Uncharacterized protein conserved in bacteria Function unknown 119384891 Common - ABC transporter related Pden_2159 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 119384051 Common - Cobyrinic acid a,c-diamide synthase Pden_1306 189 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 119383711 Common - polyhydroxyalkonate synthesis repressor, PhaR Pden_0960 67 COG5394 COG5394, Uncharacterized protein conserved in bacteria Function unknown 119382762 Common - methyltransferase GidB Pden_0005 204 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 119385176 Common - FHA domain containing protein Pden_2449 20 COG3456 COG3456, Uncharacterized conserved protein, contains FHA domain Signal transduction mechanisms 119383228 Common - thioesterase superfamily protein Pden_0476 8 COG0824 FcbC, Predicted thioesterase General function prediction only 119383452 Common - putative monovalent cation/H+ antiporter subunit E Pden_0700 64 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 119383653 Common - permease YjgP/YjgQ family protein Pden_0902 59 COG0795 COG0795, Predicted permeases General function prediction only 119384090 Common - methylisocitrate lyase Pden_1346 116 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 119385526 Common - hypothetical protein Pden_2802 78 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 119384647 Common - tyrosyl-tRNA synthetase Pden_1913 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 119383698 Common - glycine betaine/L-proline ABC transporter, ATPase subunit Pden_0947 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 119384259 Nonpathogen - hypothetical protein Pden_1519 1 None None None 119383967 Common - transposase and inactivated derivative Pden_1222 72 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 119384012 Common - NADH dehydrogenase Pden_1267 38 COG3761 COG3761, NADH:ubiquinone oxidoreductase 17.2 kD subunit Energy production and conversion 119385535 Common - NAD-dependent epimerase/dehydratase Pden_2811 142 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 119384995 Nonpathogen - hypothetical protein Pden_2263 1 None None None 119384045 Common - protein of unknown function UPF0118 Pden_1300 145 COG0628 PerM, Predicted permease General function prediction only 119385386 Common mepA penicillin-insensitive murein endopeptidase Pden_2659 40 COG3770 MepA, Murein endopeptidase Cell envelope biogenesis, outer membrane 119384315 Nonpathogen - hypothetical protein Pden_1575 3 None None None 119384219 Common - hypothetical protein Pden_1479 11 None None None 119384349 Common - binding-protein-dependent transport systems inner membrane component Pden_1609 205 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 119385123 Common - hypothetical protein Pden_2395 2 None None None 119382790 Common - binding-protein-dependent transport systems inner membrane component Pden_0033 181 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 119383071 Common - CBS domain containing protein Pden_0317 102 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 119383207 Nonpathogen - hypothetical protein Pden_0454 1 None None None 119384747 Common - phospholipid/glycerol acyltransferase Pden_2015 177 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 119384527 Common infA translation initiation factor IF-1 Pden_1790 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 119383730 Nonpathogen - hypothetical protein Pden_0979 1 None None None 119384035 Common - Orn/DAP/Arg decarboxylase 2 Pden_1290 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 119384250 Common - conjugal transfer protein precursor Pden_1510 30 COG4959 TraF, Type IV secretory pathway, protease TraF Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 119384757 Common - diguanylate phosphodiesterase Pden_2025 164 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 119383185 Nonpathogen - hypothetical protein Pden_0431 6 None None None 119383632 Common - putative phosphohistidine phosphatase, SixA Pden_0881 74 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 119385261 Common cobH precorrin-8X methylmutase Pden_2534 118 COG2082 CobH, Precorrin isomerase Coenzyme metabolism 119385295 Common - transport system permease protein Pden_2568 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 119383063 Common - periplasmic iron-binding protein Pden_0309 27 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 119384945 Common - prolipoprotein diacylglyceryl transferase Pden_2213 200 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 119383401 Common - ErfK/YbiS/YcfS/YnhG family protein Pden_0649 54 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 119384493 Common - ATP-dependent Clp protease adaptor protein ClpS Pden_1756 125 COG2127 COG2127, Uncharacterized conserved protein Function unknown 119384907 Common - nitroreductase Pden_2175 68 COG0778 NfnB, Nitroreductase Energy production and conversion 119383148 Common - hypothetical protein Pden_0394 9 None None None 119384803 Nonpathogen - hypothetical protein Pden_2071 3 None None None 119384930 Common - pyrroline-5-carboxylate reductase Pden_2198 203 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 119382862 Common - Recombinase Pden_0105 75 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 119383211 Common - Integrase, catalytic region Pden_0458 46 None None None 119383849 Common - putative transcriptional regulator, RpiR family Pden_1101 33 COG1737 RpiR, Transcriptional regulators Transcription 119384446 Common - transcriptional regulator, Fis family Pden_1709 72 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 119384976 Nonpathogen - hypothetical protein Pden_2244 6 None None None 119383040 Common - ornithine cyclodeaminase Pden_0286 88 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 119383166 Common - ATP dependent DNA ligase Pden_0412 109 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 119383380 Nonpathogen - hypothetical protein Pden_0628 2 COG4103 COG4103, Uncharacterized protein conserved in bacteria Function unknown 119382930 Common - maleylacetoacetate isomerase Pden_0174 105 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 119383595 Nonpathogen - hypothetical protein Pden_0843 2 None None None 119384812 Common - hypothetical protein Pden_2080 20 None None None 119383818 Common - hypothetical protein Pden_1069 13 None None None 119383419 Nonpathogen - hypothetical protein Pden_0667 1 None None None 119384152 Common - heme exporter protein CcmC Pden_1411 139 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 119385337 Common - TonB-dependent receptor Pden_2610 72 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 119382919 Common - MltA-interacting MipA family protein Pden_0162 44 COG3713 OmpV, Outer membrane protein V Cell envelope biogenesis, outer membrane 119384334 Common - Polyphosphate kinase Pden_1594 164 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 119384610 Common - BolA family protein Pden_1875 32 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 119383436 Common - Biopolymer transport protein ExbD/TolR Pden_0684 131 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 119383872 Common - histidine kinase Pden_1124 142 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 119383306 Common - dihydrolipoamide acetyltransferase Pden_0554 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 119385154 Common engA GTP-binding protein EngA Pden_2427 224 COG1160 COG1160, Predicted GTPases General function prediction only 119383311 Common sucC succinyl-CoA synthetase subunit beta Pden_0559 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 119385550 Common - formate dehydrogenase accessory protein FdhE Pden_2826 35 COG3058 FdhE, Uncharacterized protein involved in formate dehydrogenase formation Posttranslational modification, protein turnover, chaperones 119384617 Nonpathogen - hypothetical protein Pden_1882 2 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 119384642 Nonpathogen - hypothetical protein Pden_1907 1 None None None 119385144 Common - hypothetical protein Pden_2416 3 None None None 119383281 Common - ribosomal-protein-alanine acetyltransferase Pden_0529 171 COG0456 RimI, Acetyltransferases General function prediction only 119383247 Common - response regulator receiver protein Pden_0495 223 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 119384144 Common - protein of unknown function DUF88 Pden_1403 65 COG1432 COG1432, Uncharacterized conserved protein Function unknown 119384072 Common - binding-protein-dependent transport systems inner membrane component Pden_1327 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 119384870 Common - uracil-DNA glycosylase Pden_2138 129 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 119384117 Common - lipoyl synthase Pden_1376 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 119384201 Common - GCN5-related N-acetyltransferase Pden_1461 42 COG0456 RimI, Acetyltransferases General function prediction only 119385376 Common fliF flagellar MS-ring protein Pden_2649 124 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 119385410 Common - histidine triad (HIT) protein Pden_2683 197 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 119383807 Common - transcriptional regulator, LysR family Pden_1058 174 COG0583 LysR, Transcriptional regulator Transcription 119383748 Common - phage protein, HK97 gp10 family Pden_0997 6 None None None 119385081 Nonpathogen - hypothetical protein Pden_2351 5 None None None 119382810 Common - ABC transporter related Pden_0053 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 119383528 Common rpsE 30S ribosomal protein S5 Pden_0776 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 119385220 Common - putative transcriptional regulator, AsnC family Pden_2493 49 COG1522 Lrp, Transcriptional regulators Transcription 119384355 Common - hypothetical protein Pden_1615 5 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 119384056 Common - two component transcriptional regulator, winged helix family Pden_1311 207 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 119383292 Common - Glycine--tRNA ligase Pden_0540 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 119382780 Common - rhodanese Pden_0023 15 None None None 119383722 Nonpathogen - hypothetical protein Pden_0971 1 None None None 119385098 Common - protein of unknown function DUF779 Pden_2368 42 COG3564 COG3564, Uncharacterized protein conserved in bacteria Function unknown 119384408 Common - extracellular solute-binding protein, family 5 Pden_1671 212 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 119383139 Common - Recombinase Pden_0385 129 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 119383072 Common - transcriptional regulator, GntR family Pden_0318 111 COG1802 GntR, Transcriptional regulators Transcription 119385413 Nonpathogen - hypothetical protein Pden_2686 6 None None None 119384264 Common - putative chromosome segregation SMC protein Pden_1524 9 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 119384743 Nonpathogen - hypothetical protein Pden_2011 1 None None None 119384383 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Pden_1646 61 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 119384294 Common - 6,7-dimethyl-8-ribityllumazine synthase Pden_1554 199 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 119383850 Common - transcriptional regulator, LysR family Pden_1102 193 COG0583 LysR, Transcriptional regulator Transcription 119384194 Common - glutathione S-transferase-like protein Pden_1454 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 119384520 Common - integral membrane sensor signal transduction histidine kinase Pden_1783 46 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 119384103 Common - periplasmic binding protein Pden_1362 76 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 119382770 Common - coproporphyrinogen III oxidase Pden_0013 205 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 119383494 Common - NusG antitermination factor Pden_0742 216 COG0250 NusG, Transcription antiterminator Transcription 119385381 Common - efflux transporter, RND family, MFP subunit Pden_2654 119 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 119384421 Common - periplasmic binding protein/LacI transcriptional regulator Pden_1684 111 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 119385058 Common - protein of unknown function DUF1428 Pden_2327 39 COG5507 COG5507, Uncharacterized conserved protein Function unknown 119383788 Common - amidohydrolase Pden_1037 85 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 119382785 Common - hypothetical protein Pden_0028 9 None None None 119382833 Nonpathogen - hypothetical protein Pden_0076 1 None None None 119383951 Common - Urease accessory protein UreF Pden_1206 43 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 119383335 Common - S-adenosyl-methyltransferase MraW Pden_0583 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 119384555 Common - aminotransferase, class I and II Pden_1818 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 119383427 Common - amidohydrolase Pden_0675 162 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 119384980 Common - NADH dehydrogenase subunit C Pden_2248 176 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 119384139 Common - FAD dependent oxidoreductase Pden_1398 130 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 119385229 Common - protein of unknown function DUF81 Pden_2502 105 COG0730 COG0730, Predicted permeases General function prediction only 119383472 Common - NADH:flavin oxidoreductase/NADH oxidase Pden_0720 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 119383901 Common - Asparaginase/glutaminase Pden_1153 128 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 119383429 Common - putative hydantoin racemase protein Pden_0677 39 COG4126 COG4126, Hydantoin racemase Amino acid transport and metabolism 119384789 Nonpathogen - hypothetical protein Pden_2057 1 None None None 119384473 Common - protein of unknown function DUF451 Pden_1736 29 COG2822 COG2822, Predicted periplasmic lipoprotein involved in iron transport Inorganic ion transport and metabolism 119383254 Common - hypothetical protein Pden_0502 38 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 119383920 Common - Muconolactone delta-isomerase Pden_1175 23 COG4829 CatC1, Muconolactone delta-isomerase Secondary metabolites biosynthesis, transport, and catabolism 119384115 Common - metallophosphoesterase Pden_1374 31 COG1409 Icc, Predicted phosphohydrolases General function prediction only 119383779 Common - ABC transporter related Pden_1028 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 119383826 Common - ABC transporter related Pden_1077 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 119384590 Common - DNA polymerase I Pden_1853 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 119382880 Common - single-strand binding protein Pden_0123 169 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 119384392 Common - elongation factor P Pden_1655 213 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 119385238 Nonpathogen - hypothetical protein Pden_2511 6 None None None 119383114 Common - phage portal protein, HK97 family Pden_0360 67 COG4695 COG4695, Phage-related protein Function unknown 119384777 Common - methionyl-tRNA synthetase Pden_2045 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 119383865 Nonpathogen - protein of unknown function DUF121 Pden_1117 5 COG1920 COG1920, Uncharacterized conserved protein Function unknown 119383025 Common - putative phage cell wall peptidase, NlpC/P60 family Pden_0271 18 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 119385404 Common - transcriptional regulator, MarR family Pden_2677 98 COG1846 MarR, Transcriptional regulators Transcription 119384599 Common - hypothetical protein Pden_1862 25 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 119385460 Common - Endoribonuclease L-PSP Pden_2736 90 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 119383298 Common - monooxygenase, FAD-binding Pden_0546 70 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 119383357 Common - thiamine pyrophosphokinase Pden_0605 11 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 119384418 Common - periplasmic binding protein/LacI transcriptional regulator Pden_1681 115 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 119384745 Common - ABC-2 type transporter Pden_2013 154 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 119384705 Nonpathogen - hypothetical protein Pden_1973 2 None None None 119384806 Common - putative plasmid stability protein Pden_2074 17 COG4691 StbC, Plasmid stability protein General function prediction only 119384964 Common - NADH dehydrogenase subunit M Pden_2232 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 119383936 Common - FAD dependent oxidoreductase Pden_1191 146 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 119383815 Common - hypothetical protein Pden_1066 6 None None None 119384196 Common - transcriptional regulator, HxlR family Pden_1456 117 COG1733 COG1733, Predicted transcriptional regulators Transcription 119383658 Nonpathogen - sec-independent translocation protein mttA/Hcf106 Pden_0907 7 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 119384681 Common - putative L-sorbosone dehydrogenase Pden_1949 64 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 119384105 Common - malate synthase Pden_1364 69 COG2225 AceB, Malate synthase Energy production and conversion 119385011 Nonpathogen - hypothetical protein Pden_2279 1 None None None 119383770 Common - Creatininase Pden_1019 87 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 119383496 Common rplA 50S ribosomal protein L1 Pden_0744 248 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 119383143 Nonpathogen - hypothetical protein Pden_0389 1 None None None 119384232 Common - ABC transporter related Pden_1492 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 119383174 Common - signal peptidase I Pden_0420 208 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 119383226 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase Pden_0474 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119383953 Common ureC urease subunit alpha Pden_1208 96 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 119383570 Common - hemimethylated DNA binding protein Pden_0818 32 COG3785 COG3785, Uncharacterized conserved protein Function unknown 119384868 Common - glutamine amidotransferase of anthranilate synthase Pden_2136 237 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 119384486 Common - protein of unknown function DUF59 Pden_1749 142 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 119384464 Common - hypothetical protein Pden_1727 3 None None None 119384937 Common - heat shock protein Hsp20 Pden_2205 65 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 119383778 Common - polar amino acid ABC transporter, inner membrane subunit Pden_1027 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 119384727 Common - HemY domain protein Pden_1995 29 COG3898 COG3898, Uncharacterized membrane-bound protein Function unknown 119385426 Common flgI flagellar basal body P-ring protein Pden_2699 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 119383898 Common - ABC transporter related Pden_1150 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 119384779 Common - arginase Pden_2047 55 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 119382877 Common - DNA methylase N-4/N-6 domain protein Pden_0120 136 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 119384448 Common - hypothetical protein Pden_1711 14 None None None 119383347 Common - multi-sensor hybrid histidine kinase Pden_0595 222 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 119383417 Common - phosphate transporter Pden_0665 146 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 119383448 Common - crossover junction endodeoxyribonuclease RuvC Pden_0696 189 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 119383880 Common - PRC-barrel containing protein Pden_1132 6 None None None 119383989 Common - major facilitator superfamily MFS_1 Pden_1244 50 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 119383235 Common - PilT protein domain protein Pden_0483 54 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 119384954 Common deoA thymidine phosphorylase Pden_2222 118 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 119385350 Nonpathogen - hypothetical protein Pden_2623 1 None None None 119383520 Common rpsQ 30S ribosomal protein S17 Pden_0768 222 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 119383896 Common - polar amino acid ABC transporter, inner membrane subunit Pden_1148 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 119384820 Common - endonuclease Pden_2088 27 None None None 119384862 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Pden_2130 118 COG0388 COG0388, Predicted amidohydrolase General function prediction only 119385052 Common - Orn/DAP/Arg decarboxylase 2 Pden_2321 196 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 119385493 Common - Glutathione S-transferase, N-terminal domain Pden_2769 77 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 119384011 Common clpX ATP-dependent protease ATP-binding subunit Pden_1266 228 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 119382879 Common - hypothetical protein Pden_0122 56 COG0456 RimI, Acetyltransferases General function prediction only 119382897 Common - prevent-host-death family protein Pden_0140 9 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 119384489 Common - coproporphyrinogen III oxidase Pden_1752 113 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 119383789 Common - protein of unknown function DUF6, transmembrane Pden_1038 45 COG2962 RarD, Predicted permeases General function prediction only 119383588 Common - beta-ketoacyl synthase Pden_0836 227 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 119385208 Common - von Willebrand factor, type A Pden_2481 44 COG4548 NorD, Nitric oxide reductase activation protein Inorganic ion transport and metabolism 119384469 Common - putative glutathione S-transferase Pden_1732 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 119384577 Common - lipoprotein releasing system, transmembrane protein, LolC/E family Pden_1840 186 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 119385347 Common - kynureninase Pden_2620 93 COG3844 COG3844, Kynureninase Amino acid transport and metabolism 119383125 Common - hypothetical protein Pden_0371 3 None None None 119385433 Common - alanine dehydrogenase/PNT domain protein Pden_2709 16 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 119384433 Common - Phosphoribulokinase Pden_1696 51 COG3954 PrkB, Phosphoribulokinase Energy production and conversion 119385344 Common - iron-containing alcohol dehydrogenase Pden_2617 142 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 119384997 Common - large conductance mechanosensitive channel protein Pden_2265 144 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 119383508 Common - elongation factor Tu Pden_0756 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 119384455 Common - transcriptional regulator, LysR family Pden_1718 159 COG0583 LysR, Transcriptional regulator Transcription 119382759 Common rho transcription termination factor Rho Pden_0002 210 COG1158 Rho, Transcription termination factor Transcription 119385163 Common - hypothetical protein Pden_2436 2 None None None 119383685 Common thyX FAD-dependent thymidylate synthase Pden_0934 43 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 119383157 Common - luciferase family protein Pden_0403 106 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 119383468 Common - extracellular solute-binding protein, family 3 Pden_0716 166 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 119384677 Common - Peptidyl-dipeptidase Dcp Pden_1944 123 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 119383532 Common secY preprotein translocase subunit SecY Pden_0780 236 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 119385393 Common - molybdate ABC transporter, inner membrane subunit Pden_2666 212 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 119383612 Common - protein of unknown function DUF192 Pden_0860 89 COG1430 COG1430, Uncharacterized conserved protein Function unknown 119383782 Common - glucose-methanol-choline oxidoreductase Pden_1031 93 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 119384320 Common - Formate--tetrahydrofolate ligase Pden_1580 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 119383696 Common - Substrate-binding region of ABC-type glycine betaine transport system Pden_0945 29 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 119385512 Common - protein of unknown function DUF900, hydrolase family protein Pden_2788 24 COG4782 COG4782, Uncharacterized protein conserved in bacteria Function unknown 119385036 Common - ubiquinol-cytochrome c reductase, iron-sulfur subunit Pden_2305 104 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 119385466 Nonpathogen - hypothetical protein Pden_2742 6 None None None 119384843 Common flgC flagellar basal body rod protein FlgC Pden_2111 122 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 119383378 Common - OmpA/MotB domain protein Pden_0626 151 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 119383707 Common - hypothetical protein Pden_0956 59 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 119382989 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Pden_0235 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 119384161 Common - tRNA-dihydrouridine synthase A Pden_1420 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 119383943 Common - transcriptional regulator, MarR family Pden_1198 30 COG1846 MarR, Transcriptional regulators Transcription 119383242 Common - putative oxidoreductase Pden_0490 188 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 119385487 Nonpathogen - outer membrane porin Pden_2763 5 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 119383834 Common - glucose-methanol-choline oxidoreductase Pden_1086 72 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 119384342 Common - TonB-dependent receptor, plug Pden_1602 77 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 119385400 Common - cell divisionFtsK/SpoIIIE Pden_2673 197 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 119383313 Common - malate dehydrogenase Pden_0561 199 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 119384273 Common - probable methylase/helicase Pden_1533 22 COG1041 COG1041, Predicted DNA modification methylase DNA replication, recombination, and repair 119384327 Common - ETC complex I subunit conserved region Pden_1587 37 None None None 119382936 Common - aldehyde dehydrogenase Pden_0180 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 119385150 Common - hypothetical protein Pden_2423 2 None None None 119384153 Common - heme exporter protein CcmB Pden_1412 90 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 119383767 Nonpathogen - hypothetical protein Pden_1016 1 None None None 119385215 Common - uroporphyrin-III C-methyltransferase Pden_2488 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 119382804 Common - PAS/PAC sensor hybrid histidine kinase Pden_0047 210 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 119382943 Common - transcriptional regulator, MarR family Pden_0187 20 COG1846 MarR, Transcriptional regulators Transcription 119385022 Common - protein of unknown function DUF6, transmembrane Pden_2291 89 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 119382915 Common - hypothetical protein Pden_0158 7 None None None 119385531 Common - hypothetical protein Pden_2807 83 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 119382997 Common - Succinate-semialdehyde dehydrogenase (NAD(P)(+)) Pden_0243 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 119383171 Common - protein of unknown function DUF1491 Pden_0417 27 COG5447 COG5447, Uncharacterized conserved protein Function unknown 119385009 Common - N-formylglutamate amidohydrolase Pden_2277 37 COG3931 COG3931, Predicted N-formylglutamate amidohydrolase Amino acid transport and metabolism 119384781 Nonpathogen - hypothetical protein Pden_2049 1 None None None 119384664 Nonpathogen - hypothetical protein Pden_1931 6 COG5373 COG5373, Predicted membrane protein Function unknown 119385062 Common valS valyl-tRNA synthetase Pden_2331 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 119382920 Nonpathogen - hypothetical protein Pden_0163 1 None None None 119382841 Common - hypothetical protein Pden_0084 6 COG3895 COG3895, Predicted periplasmic protein General function prediction only 119384545 Common - cytochrome c, class I Pden_1808 57 COG3474 COG3474, Cytochrome c2 Energy production and conversion 119385005 Common rplT 50S ribosomal protein L20 Pden_2273 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 119383510 Common rpsJ 30S ribosomal protein S10 Pden_0758 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 119385253 Nonpathogen - hypothetical protein Pden_2526 7 None None None 119383084 Common - NADPH-dependent FMN reductase Pden_0330 43 COG0431 COG0431, Predicted flavoprotein General function prediction only 119383616 Common - transport system permease protein Pden_0865 186 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 119385314 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Pden_2587 200 COG0388 COG0388, Predicted amidohydrolase General function prediction only 119384308 Common - Adenosylcobinamide kinase Pden_1568 129 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 119384606 Common - Sporulation domain protein Pden_1869 12 COG3266 DamX, Uncharacterized protein conserved in bacteria Function unknown 119384798 Nonpathogen - hypothetical protein Pden_2066 3 None None None 119383366 Common - Queuosine biosynthesis protein Pden_0614 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 119384399 Common - Hemolysin-type calcium-binding region Pden_1662 102 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 119383394 Common - methionyl-tRNA formyltransferase Pden_0642 216 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 119385548 Common - aldo/keto reductase Pden_2824 187 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 119383603 Common - Nicotinamidase Pden_0851 115 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 119383628 Common - putative inner membrane protein translocase component YidC Pden_0877 213 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 119382984 Common - luciferase family protein Pden_0230 93 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 119382964 Common - hypothetical protein Pden_0210 5 None None None 119385029 Nonpathogen - glycosyl transferase, family 2 Pden_2298 6 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 119384498 Common - protein of unknown function DUF6, transmembrane Pden_1761 57 COG2510 COG2510, Predicted membrane protein Function unknown 119384181 Nonpathogen - hypothetical protein Pden_1440 1 None None None 119385359 Nonpathogen - hypothetical protein Pden_2632 1 None None None 119383500 Nonpathogen - hypothetical protein Pden_0748 1 None None None 119383316 Common - NnrUfamily protein Pden_0564 30 COG4094 COG4094, Predicted membrane protein Function unknown 119384077 Common - helix-turn-helix- domain containing protein, AraC type Pden_1332 44 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 119384145 Common - hypothetical protein Pden_1404 137 COG1360 MotB, Flagellar motor protein Cell motility and secretion 119385222 Common - cytochrome d1, heme region Pden_2495 25 COG3391 COG3391, Uncharacterized conserved protein Function unknown 119383145 Nonpathogen - hypothetical protein Pden_0391 1 None None None 119385148 Nonpathogen - hypothetical protein Pden_2420 1 None None None 119383462 Common - imidazolonepropionase Pden_0710 114 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 119383550 Common - aminotransferase, class IV Pden_0798 200 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 119383043 Common - Succinate-semialdehyde dehydrogenase (NAD(P)(+)) Pden_0289 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 119385088 Common - hypothetical protein Pden_2358 21 COG5501 COG5501, Predicted secreted protein Function unknown 119382861 Common - hypothetical protein Pden_0104 8 None None None 119385440 Nonpathogen - hypothetical protein Pden_2716 6 None None None 119384285 Common - histone family protein nucleoid-structuring protein H-NS Pden_1545 44 COG2916 Hns, DNA-binding protein H-NS General function prediction only 119385195 Common - cation diffusion facilitator family transporter Pden_2468 183 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 119384884 Common - extracellular solute-binding protein, family 1 Pden_2152 50 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 119384391 Common - Lysine--tRNA ligase Pden_1654 201 COG2269 COG2269, Truncated, possibly inactive, lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 119383137 Nonpathogen - hypothetical protein Pden_0383 1 None None None 119385438 Common - peptidase M16 domain protein Pden_2714 163 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 119382787 Common - ABC-2 type transporter Pden_0030 146 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 119385473 Common - 2-dehydro-3-deoxy-6-phosphogalactonate aldolase Pden_2749 124 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 119384241 Common - protein of unknown function DUF454 Pden_1501 75 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 119385076 Common - glycine dehydrogenase Pden_2346 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 119384420 Common - ABC transporter related Pden_1683 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 119383078 Common - putative ammonia monooxygenase Pden_0324 53 COG3180 AbrB, Putative ammonia monooxygenase General function prediction only 119383706 Common - threonyl-tRNA synthetase Pden_0955 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 119382772 Common - glutathione-dependent formaldehyde-activating enzyme Pden_0015 16 COG3791 COG3791, Uncharacterized conserved protein Function unknown 119382857 Common - MobA/MobL protein Pden_0100 121 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 119384499 Common dnaE DNA polymerase III subunit alpha Pden_1762 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 119385358 Common - hypothetical protein Pden_2631 6 None None None 119382976 Common - L-carnitine dehydratase/bile acid-inducible protein F Pden_0222 115 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 119384184 Common - hypothetical protein Pden_1443 14 COG4319 COG4319, Ketosteroid isomerase homolog Function unknown 119384611 Common glpX fructose 1,6-bisphosphatase II Pden_1876 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 119385032 Common - ABC-2 type transporter Pden_2301 17 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 119384262 Nonpathogen - hypothetical protein Pden_1522 1 None None None 119385037 Common - Cytochrome b/b6, N-terminal domain Pden_2306 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 119385091 Common - pyrroloquinoline quinone biosynthesis protein PqqC Pden_2361 36 COG5424 COG5424, Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C Coenzyme metabolism 119384838 Common - ErfK/YbiS/YcfS/YnhG family protein Pden_2106 38 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 119385341 Common - Methenyltetrahydrofolate cyclohydrolase Pden_2614 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 119385324 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein Pden_2597 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 119383364 Common - protein of unknown function DUF924 Pden_0612 63 COG3803 COG3803, Uncharacterized protein conserved in bacteria Function unknown 119384510 Common - Siderophore-interacting protein Pden_1773 55 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 119384353 Common - acyl-CoA dehydrogenase domain protein Pden_1613 159 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 119384553 Common - penicillin-binding protein, 1A family Pden_1816 200 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 119385418 Nonpathogen - protein of unknown function DUF330 Pden_2691 4 COG3009 COG3009, Uncharacterized protein conserved in bacteria Function unknown 119383766 Common - ISCc1, transposase OrfB Pden_1015 45 None None None 119385243 Nonpathogen - hypothetical protein Pden_2516 1 None None None 119384888 Common - FGGY-family pentulose kinase Pden_2156 172 COG1069 AraB, Ribulose kinase Energy production and conversion 119383183 Common - AzlC family protein Pden_0429 105 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 119384412 Common - thiamine pyrophosphate enzyme domain protein TPP-binding Pden_1675 221 COG3962 COG3962, Acetolactate synthase Amino acid transport and metabolism 119385159 Common - methylated-DNA--protein-cysteine methyltransferase Pden_2432 193 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 119385141 Common - ABC transporter related Pden_2413 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 119384525 Common - integral membrane sensor signal transduction histidine kinase Pden_1788 217 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 119384749 Common - ABC transporter related Pden_2017 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 119385297 Common - protein of unknown function DUF1178 Pden_2570 47 COG5319 COG5319, Uncharacterized protein conserved in bacteria Function unknown 119384853 Common - dTDP-glucose 4,6-dehydratase Pden_2121 232 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 119383643 Common - YceI family protein Pden_0892 115 COG2353 COG2353, Uncharacterized conserved protein Function unknown 119385051 Common - hypothetical protein Pden_2320 24 COG3673 COG3673, Uncharacterized conserved protein Function unknown 119383164 Common - putative transcriptional regulator, AsnC family Pden_0410 145 COG1522 Lrp, Transcriptional regulators Transcription 119383424 Common - putative adenylate-forming enzyme Pden_0672 36 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 119383541 Common - CrcB protein Pden_0789 67 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 119383875 Nonpathogen - hypothetical protein Pden_1127 1 None None None 119383913 Common - periplasmic binding protein Pden_1168 84 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 119383802 Common - Aldehyde dehydrogenase (NAD(+)) Pden_1051 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 119385301 Common - NUDIX hydrolase Pden_2574 126 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 119384175 Common - putative transcriptional regulator, GntR family Pden_1434 193 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 119384074 Common - thioredoxin reductase-like Pden_1329 26 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 119384221 Common - AAA ATPase Pden_1481 63 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 119383300 Common - ATPase associated with various cellular activities, AAA_5 Pden_0548 103 COG0714 COG0714, MoxR-like ATPases General function prediction only 119384405 Common - ABC transporter related Pden_1668 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 119383717 Nonpathogen - hypothetical protein Pden_0966 1 None None None 119384409 Common - Myo-inositol catabolism IolB domain protein Pden_1672 53 COG3718 IolB, Uncharacterized enzyme involved in inositol metabolism Carbohydrate transport and metabolism 119384386 Common - 3-hydroxydecanoyl-(acyl carrier protein) dehydratase Pden_1649 87 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 119383798 Common - extracellular solute-binding protein, family 1 Pden_1047 78 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 119384905 Nonpathogen - hypothetical protein Pden_2173 6 None None None 119385102 Common - exodeoxyribonuclease III Xth Pden_2372 195 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 119383473 Common - Patatin Pden_0721 49 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 119384712 Common - molybdopterin binding domain Pden_1980 165 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 119385385 Common - major facilitator superfamily MFS_1 Pden_2658 70 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 119384947 Common - pseudouridine synthase, RluA family Pden_2215 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 119385327 Common - two component transcriptional regulator, winged helix family Pden_2600 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 119384427 Common - transcriptional regulator, BadM/Rrf2 family Pden_1690 146 COG1959 COG1959, Predicted transcriptional regulator Transcription 119383662 Common - Choloylglycine hydrolase Pden_0911 46 COG3049 COG3049, Penicillin V acylase and related amidases Cell envelope biogenesis, outer membrane 119383941 Common - transcriptional regulator, TetR family Pden_1196 31 COG1309 AcrR, Transcriptional regulator Transcription 119384718 Common - phospholipase D/Transphosphatidylase Pden_1986 152 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 119385161 Common - hypothetical protein Pden_2434 9 None None None 119383434 Common - 4-hydroxybenzoyl-CoA thioesterase Pden_0682 147 COG0824 FcbC, Predicted thioesterase General function prediction only 119383213 Common - hypothetical protein Pden_0460 8 None None None 119383255 Common - ABC transporter related Pden_0503 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 119383083 Common - hypothetical protein Pden_0329 28 COG5649 COG5649, Uncharacterized conserved protein Function unknown 119384767 Common - VacJ family lipoprotein Pden_2035 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 119383959 Common - regulatory protein, ArsR Pden_1214 65 COG0640 ArsR, Predicted transcriptional regulators Transcription 119383308 Nonpathogen - hypothetical protein Pden_0556 1 None None None 119385066 Common - FAD dependent oxidoreductase Pden_2335 64 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 119383522 Common rplX 50S ribosomal protein L24 Pden_0770 212 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 119384737 Common - acyl-CoA synthetase Pden_2005 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 119383096 Common - DNA polymerase III, beta subunit Pden_0342 196 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 119384640 Common - hypothetical protein Pden_1905 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 119384759 Common - acetoacetyl-CoA reductase Pden_2027 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119384346 Nonpathogen - Methyltransferase type 12 Pden_1606 5 None None None 119384313 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Pden_1573 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 119385468 Common - acetyltransferase-like Pden_2744 14 COG2388 COG2388, Predicted acetyltransferase General function prediction only 119383101 Nonpathogen - hypothetical protein Pden_0347 1 None None None 119382845 Common - flagellin modification protein FlmD Pden_0088 19 COG3980 spsG, Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase Cell envelope biogenesis, outer membrane 119384730 Common - putative metalloendopeptidase, glycoprotease family Pden_1998 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 119383033 Common - putative transcriptional regulator, GntR family Pden_0279 143 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 119383111 Nonpathogen - hypothetical protein Pden_0357 1 None None None 119383724 Nonpathogen - hypothetical protein Pden_0973 1 None None None 119383736 Common - HNH endonuclease Pden_0985 23 COG1403 McrA, Restriction endonuclease Defense mechanisms 119385372 Common - chemotaxis protein MotA Pden_2645 77 COG1291 MotA, Flagellar motor component Cell motility and secretion 119383669 Common - alpha/beta hydrolase fold Pden_0918 128 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 119383853 Common - peptidase M19, renal dipeptidase Pden_1105 100 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 119385170 Common - Uncharacterized conserved protein UCP028301 Pden_2443 50 COG3516 COG3516, Uncharacterized protein conserved in bacteria Function unknown 119384018 Common - lipid A biosynthesis acyltransferase Pden_1273 119 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 119385101 Common - Thioredoxin domain Pden_2371 229 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 119383833 Common - conjugal transfer protein Pden_1084 23 COG3701 TrbF, Type IV secretory pathway, TrbF components Intracellular trafficking and secretion 119385187 Common - Polypeptide-transport-associated domain protein, ShlB-type Pden_2460 50 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 119384092 Common - 2-methylcitrate dehydratase Pden_1348 64 COG2079 PrpD, Uncharacterized protein involved in propionate catabolism General function prediction only 119382993 Common - extracellular solute-binding protein, family 5 Pden_0239 197 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 119382909 Common - conjugal transfer protein TrbJ Pden_0152 22 COG5314 COG5314, Conjugal transfer/entry exclusion protein Intracellular trafficking and secretion 119383270 Common - Superoxide dismutase Pden_0518 207 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 119384678 Common - UBA/THIF-type NAD/FAD binding protein Pden_1945 212 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 119385169 Common - ImpA domain protein Pden_2442 8 COG3515 COG3515, Uncharacterized protein conserved in bacteria Function unknown 119385556 Common - Rieske (2Fe-2S) domain protein Pden_2832 84 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 119383992 Common - glutathionylspermidine synthase Pden_1247 52 COG0754 Gsp, Glutathionylspermidine synthase Amino acid transport and metabolism 119384189 Common - phenazine biosynthesis protein PhzF family Pden_1448 121 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 119385528 Common - Pseudouridylate synthase Pden_2804 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 119385121 Common - 6-phosphogluconate dehydrogenase Pden_2393 178 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 119385177 Nonpathogen - hypothetical protein Pden_2450 4 COG3521 COG3521, Uncharacterized protein conserved in bacteria Function unknown 119384605 Common - Beta-N-acetylhexosaminidase Pden_1868 169 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 119383266 Common - Sarcosine oxidase, delta subunit, heterotetrameric Pden_0514 33 COG4311 SoxD, Sarcosine oxidase delta subunit Amino acid transport and metabolism 119384893 Common - helix-turn-helix- domain containing protein, AraC type Pden_2161 140 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 119383654 Common - leucyl aminopeptidase Pden_0903 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 119383948 Nonpathogen - hypothetical protein Pden_1203 1 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 119383684 Common - basic membrane lipoprotein Pden_0933 93 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 119383630 Common - GTPase EngB Pden_0879 186 COG0218 COG0218, Predicted GTPase General function prediction only 119382779 Common - extracellular solute-binding protein, family 3 Pden_0022 19 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 119384535 Common - sulfate ABC transporter, periplasmic sulfate-binding protein Pden_1798 88 COG4150 CysP, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 119384722 Nonpathogen - hypothetical protein Pden_1990 4 None None None 119384633 Common - transcriptional regulator, TetR family Pden_1898 57 COG1309 AcrR, Transcriptional regulator Transcription 119384646 Common anmK anhydro-N-acetylmuramic acid kinase Pden_1912 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 119383846 Common - glucose-methanol-choline oxidoreductase Pden_1098 101 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 119383051 Common - ABC transporter related Pden_0297 249 COG4604 CeuD, ABC-type enterochelin transport system, ATPase component Inorganic ion transport and metabolism 119383214 Common - Integrase, catalytic region Pden_0461 25 None None None 119385332 Common - ABC transporter related Pden_2605 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 119383741 Common - peptidase S14, ClpP Pden_0990 40 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 119384021 Nonpathogen - hypothetical protein Pden_1276 1 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 119384156 Common secF preprotein translocase subunit SecF Pden_1415 202 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 119383003 Common - inner-membrane translocator Pden_0249 125 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 119385484 Common rpsO 30S ribosomal protein S15 Pden_2760 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 119384628 Common - methionine-R-sulfoxide reductase Pden_1893 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 119385191 Common - hypothetical protein Pden_2464 13 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 119384398 Common - Propeptide, PepSY amd peptidase M4 Pden_1661 26 COG3212 COG3212, Predicted membrane protein Function unknown 119385290 Common - cytochrome B561 Pden_2563 14 COG3038 CybB, Cytochrome B561 Energy production and conversion 119384204 Common - aminotransferase, class IV Pden_1464 213 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 119383383 Common - 3-mercaptopyruvate sulfurtransferase Pden_0631 146 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 119385129 Nonpathogen - hypothetical protein Pden_2401 1 None None None 119384268 Common - protein of unknown function DUF262 Pden_1528 37 COG3472 COG3472, Uncharacterized conserved protein Function unknown 119383598 Common - lipopolysaccharide biosynthesis Pden_0846 39 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 119383129 Nonpathogen - hypothetical protein Pden_0375 1 None None None 119384650 Common - peptidyl-prolyl cis-trans isomerase, cyclophilin type Pden_1916 200 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 119385283 Common - uroporphyrin-III C-methyltransferase Pden_2556 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 119382957 Common - luciferase family protein Pden_0203 107 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 119383067 Nonpathogen - hypothetical protein Pden_0313 2 None None None 119385068 Common - Rhomboid family protein Pden_2337 130 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 119383156 Common - NAD-dependent epimerase/dehydratase Pden_0402 107 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 119383497 Common rplJ 50S ribosomal protein L10 Pden_0745 200 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 119384911 Common - response regulator receiver protein Pden_2179 41 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 119384064 Common - peptidase S13, D-Ala-D-Ala carboxypeptidase C Pden_1319 33 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 119384434 Common - transketolase Pden_1697 221 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 119383108 Nonpathogen - hypothetical protein Pden_0354 1 None None None 119385198 Common - binding-protein-dependent transport systems inner membrane component Pden_2471 138 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 119384444 Common - hypothetical protein Pden_1707 5 None None None 119385180 Common - ImcF domain protein Pden_2453 47 COG3523 IcmF, Uncharacterized protein conserved in bacteria Function unknown 119383564 Common - phosphoserine phosphatase SerB Pden_0812 149 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 119384692 Common - hypothetical protein Pden_1960 18 None None None 119384228 Common - putative sulfonate/nitrate transport system substrate-binding protein Pden_1488 17 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 119383447 Common ruvA Holliday junction DNA helicase motor protein Pden_0695 209 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 162139378 Common rpsM 30S ribosomal protein S13 Pden_0782 247 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 119383960 Common - Activator of Hsp90 ATPase 1 family protein Pden_1215 36 COG3832 COG3832, Uncharacterized conserved protein Function unknown 119385451 Common - type I secretion outer membrane protein, TolC family Pden_2727 105 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 119382928 Common - benzoate-CoA ligase family Pden_0172 222 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 119385041 Nonpathogen - hypothetical protein Pden_2310 1 None None None 119383275 Common - tRNA 2-selenouridine synthase Pden_0523 66 COG2603 COG2603, Predicted ATPase General function prediction only 119383600 Common - malic enzyme Pden_0848 216 COG0281 SfcA, Malic enzyme Energy production and conversion 119385338 Common - putative transcriptional regulator, XRE family Pden_2611 13 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 119384496 Common - putative transcriptional regulator, AsnC family Pden_1759 134 COG1522 Lrp, Transcriptional regulators Transcription 119382889 Common - putative replication protein A Pden_0132 33 COG5534 COG5534, Plasmid replication initiator protein DNA replication, recombination, and repair 119383239 Nonpathogen - hypothetical protein Pden_0487 1 None None None 119384866 Common - hypothetical protein Pden_2134 236 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 119384360 Nonpathogen - hypothetical protein Pden_1621 1 None None None 119383605 Common nadE NAD synthetase Pden_0853 233 COG0171 NadE, NAD synthase Coenzyme metabolism 119384341 Common - major facilitator superfamily MFS_1 Pden_1601 170 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 119384916 Common - Abortive infection protein Pden_2184 5 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 119383981 Common - Uracil-DNA glycosylase superfamily Pden_1236 67 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 119384795 Common - conserved hypothetical phage terminase large subunit Pden_2063 37 COG4626 COG4626, Phage terminase-like protein, large subunit General function prediction only 119383966 Common - transposase, IS4 family protein Pden_1221 46 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 119383690 Common aspA aspartate ammonia-lyase Pden_0939 220 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 119384276 Common - hypothetical protein Pden_1536 9 None None None 119384662 Common - cell wall hydrolase, SleB Pden_1928 25 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 119383089 Common - phage integrase family protein Pden_0335 41 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 119384307 Common - Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Pden_1567 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 119385545 Nonpathogen - hypothetical protein Pden_2821 2 None None None 119382812 Common - ribosomal protein L36 Pden_0055 75 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 119385491 Common - DNA polymerase III, delta subunit Pden_2767 28 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 119383318 Common - MaoC domain protein dehydratase Pden_0566 58 COG2030 MaoC, Acyl dehydratase Lipid metabolism 119383679 Common - iron-sulfur cluster assembly accessory protein Pden_0928 164 COG0316 IscA, Uncharacterized conserved protein Function unknown 119383198 Common - hypothetical protein Pden_0444 5 None None None 119383209 Nonpathogen - hypothetical protein Pden_0456 1 None None None 119384300 Common - Capsule polysaccharide biosynthesis Pden_1560 30 COG3563 KpsC, Capsule polysaccharide export protein Cell envelope biogenesis, outer membrane 119384506 Common - 3-oxoacyl-(acyl-carrier-protein) reductase Pden_1769 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119384720 Common - FolC bifunctional protein Pden_1988 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 119383502 Nonpathogen - hypothetical protein Pden_0750 1 None None None 119383451 Common - putative monovalent cation/H+ antiporter subunit D Pden_0699 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 119383080 Common - luciferase family protein Pden_0326 67 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 119384822 Common - hypothetical protein Pden_2090 37 None None None 119385349 Common - hypothetical protein Pden_2622 3 None None None 119385476 Common - transcriptional regulator, GntR family Pden_2752 135 COG1802 GntR, Transcriptional regulators Transcription 119383506 Common - 30S ribosomal protein S7 Pden_0754 249 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 119384775 Common - GcrA cell cycle regulator Pden_2043 33 COG5352 COG5352, Uncharacterized protein conserved in bacteria Function unknown 119384367 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Pden_1629 103 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 119383177 Common - 4-diphosphocytidyl-2C-methyl-D-erythritol kinase Pden_0423 108 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 119383170 Common gyrB DNA gyrase subunit B Pden_0416 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 119383729 Nonpathogen - hypothetical protein Pden_0978 1 None None None 119383453 Common - multiple resistance and pH regulation protein F Pden_0701 71 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 119385186 Common - OmpA/MotB domain protein Pden_2459 130 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 119384239 Common - TonB-dependent receptor Pden_1499 102 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 119383539 Common - N-acyl-L-homoserine lactone synthetase-like Pden_0787 12 COG3916 LasI, N-acyl-L-homoserine lactone synthetase Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 119385397 Common - Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family Pden_2670 131 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 119384130 Common - Alcohol dehydrogenase, zinc-binding domain protein Pden_1389 78 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 119384168 Common - TonB-dependent receptor Pden_1427 94 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 119383843 Common - Aspartate ammonia-lyase Pden_1095 201 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 119385278 Common - electron transfer flavoprotein, alpha subunit Pden_2551 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 119384124 Nonpathogen - hypothetical protein Pden_1383 1 None None None 119384328 Common - excinuclease ABC subunit B Pden_1588 228 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 119382849 Nonpathogen - hypothetical protein Pden_0092 1 None None None 119382968 Common - arsenical-resistance protein Pden_0214 133 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 119384348 Common - extracellular solute-binding protein, family 5 Pden_1608 163 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 119382904 Common - conjugation TrbI family protein Pden_0147 56 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 119384053 Common - excinuclease ABC subunit B Pden_1308 228 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 119384710 Common - periplasmic binding protein/LacI transcriptional regulator Pden_1978 126 COG1609 PurR, Transcriptional regulators Transcription 119382847 Common - hypothetical protein Pden_0090 22 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 119383377 Common ubiA prenyltransferase Pden_0625 158 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 119383530 Nonpathogen - hypothetical protein Pden_0778 3 None None None 119383618 Common - protein of unknown function UPF0066 Pden_0867 89 COG1720 COG1720, Uncharacterized conserved protein Function unknown 119383027 Common - hypothetical protein Pden_0273 25 COG5448 COG5448, Uncharacterized conserved protein Function unknown 119382802 Common - 3-dehydroquinate dehydratase, type II Pden_0045 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 119384669 Common lipB lipoyltransferase Pden_1936 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 119384676 Common - hypothetical protein Pden_1943 10 None None None 119384479 Common - D-tyrosyl-tRNA deacylase Pden_1742 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 119385334 Nonpathogen - hypothetical protein Pden_2607 7 COG5375 COG5375, Uncharacterized protein conserved in bacteria Function unknown 119385313 Common - glutaredoxin 3 Pden_2586 137 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 119385514 Common hslU ATP-dependent protease ATP-binding subunit Pden_2790 209 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 119385486 Common - alanine racemase domain protein Pden_2762 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 119383049 Common - transcriptional regulator, MarR family Pden_0295 14 COG1846 MarR, Transcriptional regulators Transcription 119383221 Common - binding-protein-dependent transport systems inner membrane component Pden_0469 207 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 119384544 Common - extracellular solute-binding protein, family 5 Pden_1807 157 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 119382820 Common - putative sulfite oxidase subunit YedY Pden_0063 125 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 119384801 Common - HNH endonuclease Pden_2069 29 COG1403 McrA, Restriction endonuclease Defense mechanisms 119382828 Nonpathogen - hypothetical protein Pden_0071 1 None None None 119383122 Nonpathogen - hypothetical protein Pden_0368 1 None None None 119383656 Common - hypothetical protein Pden_0905 54 COG3577 COG3577, Predicted aspartyl protease General function prediction only 119384563 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Pden_1826 155 COG1146 COG1146, Ferredoxin Energy production and conversion 119385153 Common - Pyrrolo-quinoline quinone Pden_2426 120 COG1520 COG1520, FOG: WD40-like repeat Function unknown 119385262 Common - precorrin-2 C20-methyltransferase Pden_2535 88 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 119383817 Common - transcriptional regulator, MarR family Pden_1068 122 COG1846 MarR, Transcriptional regulators Transcription 119385179 Common - OmpA/MotB domain protein Pden_2452 56 COG3455 COG3455, Uncharacterized protein conserved in bacteria Function unknown 119384472 Common - Dyp-type peroxidase family Pden_1735 42 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 119385053 Common - putative transcriptional regulator, AsnC family Pden_2322 131 COG1522 Lrp, Transcriptional regulators Transcription 119383998 Common - protein of unknown function DUF125, transmembrane Pden_1253 84 COG1814 COG1814, Uncharacterized membrane protein Function unknown 119384104 Common - isocitrate lyase Pden_1363 120 COG2224 AceA, Isocitrate lyase Energy production and conversion 119383971 Nonpathogen - hypothetical protein Pden_1226 1 None None None 119382917 Common - acriflavin resistance protein Pden_0160 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 119383625 Common - protein of unknown function DUF37 Pden_0874 181 COG0759 COG0759, Uncharacterized conserved protein Function unknown 119383348 Nonpathogen - hypothetical protein Pden_0596 8 None None None 119384085 Nonpathogen - hypothetical protein Pden_1340 6 None None None 119383887 Common - TonB-dependent siderophore receptor Pden_1139 121 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 119382791 Common - ABC transporter related Pden_0034 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 119385236 Common - NUDIX hydrolase Pden_2509 119 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 119384952 Common - adenosine deaminase Pden_2220 109 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 119383651 Common - Organic solvent tolerance protein Pden_0900 78 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 119383647 Common - hypothetical protein Pden_0896 29 COG5373 COG5373, Predicted membrane protein Function unknown 119385449 Common - hypothetical protein Pden_2725 102 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 119383237 Common - transcriptional regulator, XRE family Pden_0485 37 COG2944 COG2944, Predicted transcriptional regulator Transcription 119383772 Common - spermidine/putrescine ABC transporter, periplasmic binding protein, putative Pden_1021 95 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 119383409 Common - hypothetical protein Pden_0657 53 COG3749 COG3749, Uncharacterized protein conserved in bacteria Function unknown 119385425 Common - putative flagellar hook-associated protein Pden_2698 23 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 119383345 Common - hypothetical protein Pden_0593 43 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 119384583 Nonpathogen - Cbb3-type cytochrome oxidase component Pden_1846 5 COG4736 CcoQ, Cbb3-type cytochrome oxidase, subunit 3 Posttranslational modification, protein turnover, chaperones 119383894 Common - transcriptional regulator, LysR family Pden_1146 185 COG0583 LysR, Transcriptional regulator Transcription 119385421 Common - Paraquat-inducible protein A Pden_2694 54 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 119385377 Nonpathogen - hypothetical protein Pden_2650 1 None None None 119384483 Common - Nucleoside-diphosphate kinase Pden_1746 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 119382892 Nonpathogen - hypothetical protein Pden_0135 1 None None None 119384445 Common - ABC transporter related Pden_1708 224 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 119384197 Common - alpha/beta hydrolase Pden_1457 27 COG4757 COG4757, Predicted alpha/beta hydrolase General function prediction only 119385064 Common - hypothetical protein Pden_2333 13 None None None 119384006 Common - protein of unknown function UPF0029 Pden_1261 7 COG1739 COG1739, Uncharacterized conserved protein Function unknown 119384621 Common - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase Pden_1886 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 119383863 Common - Radical SAM domain protein Pden_1115 86 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 119384938 Nonpathogen - protein of unknown function DUF1150 Pden_2206 8 COG5568 COG5568, Uncharacterized small protein Function unknown 119383330 Common - N-acetylmuramoyl-L-alanine amidase, family 2 Pden_0578 110 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 119383726 Common - putative phage repressor Pden_0975 9 COG2932 COG2932, Predicted transcriptional regulator Transcription 119383812 Common - Aspartate racemase-like Pden_1063 58 COG1794 RacX, Aspartate racemase Cell envelope biogenesis, outer membrane 119385407 Common - Glucokinase Pden_2680 89 COG0837 Glk, Glucokinase Carbohydrate transport and metabolism 119385357 Common - flagellar motor protein Pden_2630 89 COG1291 MotA, Flagellar motor component Cell motility and secretion 119382962 Common - 4-oxalocrotonate tautomerase Pden_0208 13 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 119384033 Common - putative monovalent cation/H+ antiporter subunit C Pden_1288 90 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 119383752 Common - hypothetical protein Pden_1001 3 None None None 119384988 Common - hypothetical protein Pden_2256 25 COG4912 COG4912, Predicted DNA alkylation repair enzyme DNA replication, recombination, and repair 119384568 Common - alpha/beta hydrolase fold Pden_1831 50 COG2267 PldB, Lysophospholipase Lipid metabolism 119383976 Nonpathogen - hypothetical protein Pden_1231 1 None None None 119383855 Common - Alcohol dehydrogenase GroES domain protein Pden_1107 102 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 119384597 Common - fatty acid/phospholipid synthesis protein Pden_1860 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 119385497 Common - glycosyl transferase, group 1 Pden_2773 209 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 119384113 Common - phosphoesterase or phosphohydrolase-like Pden_1372 18 COG4186 COG4186, Predicted phosphoesterase or phosphohydrolase General function prediction only 119384594 Common - glycosyl transferase, family 14 Pden_1857 8 None None None 119385302 Common - Polynucleotide adenylyltransferase region Pden_2575 202 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 119385503 Common - integral membrane sensor signal transduction histidine kinase Pden_2779 169 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 119383480 Common - FAD-binding 9, siderophore-interacting domain protein Pden_0728 56 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 119383930 Common - ornithine cyclodeaminase/mu-crystallin Pden_1185 94 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 119383444 Common - hypothetical protein Pden_0692 61 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 119384990 Common - protein of unknown function DUF1013 Pden_2258 41 COG3820 COG3820, Uncharacterized protein conserved in bacteria Function unknown 119384425 Nonpathogen - hypothetical protein Pden_1688 13 COG5615 COG5615, Predicted integral membrane protein Function unknown 119382925 Common - regulatory proteins, IclR Pden_0169 111 COG1414 IclR, Transcriptional regulator Transcription 119384999 Common rpsU 30S ribosomal protein S21 Pden_2267 40 None None None 119382900 Common - hypothetical protein Pden_0143 23 None None None 119383585 Common - Hemolysin-type calcium-binding region Pden_0833 68 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 119385117 Common - GCN5-related N-acetyltransferase Pden_2388 17 COG0456 RimI, Acetyltransferases General function prediction only 119385023 Nonpathogen - hypothetical protein Pden_2292 5 None None None 119385043 Common uvrC excinuclease ABC subunit C Pden_2312 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 119384467 Nonpathogen - hypothetical protein Pden_1730 1 None None None 119384370 Nonpathogen - hypothetical protein Pden_1632 1 None None None 119384248 Common - Lytic transglycosylase, catalytic Pden_1508 158 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 119384377 Common - phosphate acetyltransferase Pden_1640 153 COG0280 Pta, Phosphotransacetylase Energy production and conversion 119383414 Common - amino acid carrier protein Pden_0662 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 119382886 Common - hypothetical protein Pden_0129 13 None None None 119384725 Nonpathogen - hypothetical protein Pden_1993 1 None None None 119385364 Nonpathogen - hypothetical protein Pden_2637 3 COG4695 COG4695, Phage-related protein Function unknown 119383569 Common - CreA family protein Pden_0817 56 COG3045 CreA, Uncharacterized protein conserved in bacteria Function unknown 119384783 Nonpathogen - hypothetical protein Pden_2051 1 None None None 119384613 Nonpathogen - hypothetical protein Pden_1878 1 None None None 119384830 Common - Alkane 1-monooxygenase Pden_2098 26 None None None 119384588 Common - coproporphyrinogen III oxidase Pden_1851 203 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 119383337 Common - Peptidoglycan glycosyltransferase Pden_0585 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 119382795 Common thiE thiamine-phosphate pyrophosphorylase Pden_0038 199 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 119383039 Common - threonine dehydratase Pden_0285 191 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 119384230 Common - ABC transporter related Pden_1490 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 119383286 Common truA tRNA pseudouridine synthase A Pden_0534 214 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 119382863 Common - Recombinase Pden_0106 83 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 119384811 Nonpathogen - hypothetical protein Pden_2079 1 None None None 119382830 Common - Cobyrinic acid a,c-diamide synthase Pden_0073 223 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 119383291 Nonpathogen - signal transduction histidine kinase regulating citrate/malate metabolism Pden_0539 6 None None None 119383515 Common rpsS 30S ribosomal protein S19 Pden_0763 240 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 119384841 Common - ATPase, FliI/YscN family Pden_2109 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 119383575 Common - protein of unknown function DUF404 Pden_0823 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 119384400 Common - Rieske (2Fe-2S) domain protein Pden_1663 28 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 119383549 Common - hypothetical protein Pden_0797 76 None None None 119385436 Nonpathogen - hypothetical protein Pden_2712 8 None None None 119383062 Common - Uncharacterized protein UPF0065 Pden_0308 74 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 119383432 Common - transcriptional regulator, GntR family Pden_0680 118 COG1802 GntR, Transcriptional regulators Transcription 119383188 Common - acyl-CoA dehydrogenase domain protein Pden_0434 151 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 119383302 Common - Lytic transglycosylase, catalytic Pden_0550 27 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 119384963 Common - NADH dehydrogenase subunit N Pden_2231 209 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 119384173 Common - BioY protein Pden_1432 9 COG1268 BioY, Uncharacterized conserved protein General function prediction only 119383225 Common - Hydantoinase B/oxoprolinase Pden_0473 89 COG0146 HyuB, N-methylhydantoinase B/acetone carboxylase, alpha subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 119385157 Nonpathogen - SoxS Pden_2430 8 None None None 119384388 Common - short-chain dehydrogenase/reductase SDR Pden_1651 234 COG0623 FabI, Enoyl- acyl-carrier-protein 119384449 Common - glucose-methanol-choline oxidoreductase Pden_1712 90 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 119383873 Common - ATPase associated with various cellular activities, AAA_3 Pden_1125 192 COG0714 COG0714, MoxR-like ATPases General function prediction only 119383911 Common - major facilitator superfamily MFS_1 Pden_1166 97 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 119383703 Common - DSBA oxidoreductase Pden_0952 81 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 119384752 Common - diaminopimelate decarboxylase Pden_2020 218 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 119384581 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Pden_1844 77 COG0348 NapH, Polyferredoxin Energy production and conversion 119384331 Common - Antibiotic biosynthesis monooxygenase Pden_1591 7 COG1359 COG1359, Uncharacterized conserved protein Function unknown 119382934 Common - ABC transporter related Pden_0178 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 119383804 Nonpathogen - hypothetical protein Pden_1055 1 None None None 119384851 Common - glucose-1-phosphate thymidylyltransferase Pden_2119 232 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 119385072 Common - molybdopterin converting factor, subunit 1 Pden_2341 62 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 119383681 Nonpathogen - hypothetical protein Pden_0930 1 None None None 119382789 Common - molybdopterin-guanine dinucleotide biosynthesis protein A Pden_0032 120 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 119384551 Common - Patatin Pden_1814 33 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 119383478 Common - Biopolymer transport protein ExbD/TolR Pden_0726 130 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 119385152 Nonpathogen - hypothetical protein Pden_2425 12 COG4649 COG4649, Uncharacterized protein conserved in bacteria Function unknown 119383755 Common - hypothetical protein Pden_1004 9 COG4733 COG4733, Phage-related protein, tail component Function unknown 119383641 Common rpsR 30S ribosomal protein S18 Pden_0890 215 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 119383591 Common - 4'-phosphopantetheinyl transferase Pden_0839 29 COG2977 EntD, Phosphopantetheinyl transferase component of siderophore synthetase Secondary metabolites biosynthesis, transport, and catabolism 119383471 Common - ABC transporter related Pden_0719 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 119384070 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Pden_1325 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 119385490 Nonpathogen - secreted periplasmic protein Pden_2766 9 COG5468 COG5468, Predicted secreted (periplasmic) protein Function unknown 119383499 Common rpoB DNA-directed RNA polymerase subunit beta Pden_0747 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 119384701 Common - hypothetical protein Pden_1969 3 None None None 119384903 Nonpathogen - hypothetical protein Pden_2171 3 None None None 119383153 Common - Polyprenyl synthetase Pden_0399 241 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 119385234 Common - peptidase M23B Pden_2507 66 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 119383103 Nonpathogen - hypothetical protein Pden_0349 1 None None None 119385383 Common - ATP-dependent DNA helicase RecQ Pden_2656 212 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 119384172 Common - transcriptional regulator, GntR family Pden_1431 133 COG1802 GntR, Transcriptional regulators Transcription 119382907 Common - TrbL/VirB6 plasmid conjugal transfer protein Pden_0150 39 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 119384574 Common - protein of unknown function UPF0060 Pden_1837 78 COG1742 COG1742, Uncharacterized conserved protein Function unknown 119384949 Nonpathogen - hypothetical protein Pden_2217 6 None None None 119382926 Common - thioesterase superfamily protein Pden_0170 12 COG0824 FcbC, Predicted thioesterase General function prediction only 119383710 Nonpathogen - hypothetical protein Pden_0959 6 None None None 119382855 Nonpathogen - Conjugal transfer TraD family protein Pden_0098 13 None None None 119383076 Common - Allophanate hydrolase subunit 2 Pden_0322 114 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 119383321 Common sdhA succinate dehydrogenase flavoprotein subunit Pden_0569 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 119383587 Nonpathogen - hypothetical protein Pden_0835 9 None None None 119384362 Common flgD flagellar basal body rod modification protein Pden_1623 84 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 119383517 Common rpsC 30S ribosomal protein S3 Pden_0765 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 119383092 Nonpathogen - hypothetical protein Pden_0338 1 None None None 119384436 Common rbcL ribulose bisophosphate carboxylase Pden_1699 67 COG1850 RbcL, Ribulose 1,5-bisphosphate carboxylase, large subunit Carbohydrate transport and metabolism 119383016 Common - hypothetical protein Pden_0262 7 None None None 119384517 Common - efflux transporter, RND family, MFP subunit Pden_1780 158 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 119383667 Common - transcriptional regulator, TraR/DksA family Pden_0916 37 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 119385078 Common - glycine cleavage system T protein Pden_2348 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 119384501 Common - inner-membrane translocator Pden_1764 85 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 119385439 Common - peptidase M16 domain protein Pden_2715 196 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 119383835 Common - ABC transporter related Pden_1087 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 119384836 Common - major facilitator superfamily MFS_1 Pden_2104 122 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 119383491 Common - ABC transporter related Pden_0739 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 119383637 Nonpathogen - hypothetical protein Pden_0886 1 None None None 119383557 Nonpathogen - Transglycosylase-associated protein Pden_0805 1 COG2261 COG2261, Predicted membrane protein Function unknown 119384319 Common nadD nicotinic acid mononucleotide adenyltransferase Pden_1579 165 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 119385015 Nonpathogen - hypothetical protein Pden_2283 1 None None None 119383163 Common - aminotransferase, class V Pden_0409 205 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 119383339 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase Pden_0587 202 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 119384081 Common - Phosphoribosyl-AMP cyclohydrolase Pden_1336 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 119383645 Common - peptide chain release factor 1 Pden_0894 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 119383715 Nonpathogen - hypothetical protein Pden_0964 1 None None None 119382797 Common - thiamine biosynthesis protein ThiS Pden_0040 21 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 119384404 Common - ABC transporter related Pden_1667 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 119383406 Nonpathogen - hypothetical protein Pden_0654 6 None None None 119385093 Common - beta-lactamase domain protein Pden_2363 82 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 119384185 Common - Cupin 2, conserved barrel domain protein Pden_1444 21 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 119383923 Common - 2-chlorobenzoate 1,2-dioxygenase Pden_1178 28 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 119382998 Common - Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein Pden_0244 102 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 119385361 Common - HNH endonuclease Pden_2634 12 COG1403 McrA, Restriction endonuclease Defense mechanisms 119383135 Nonpathogen - hypothetical protein Pden_0381 2 None None None 119382974 Common - luciferase family protein Pden_0220 69 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 119383058 Common - transcriptional regulator, LysR family Pden_0304 175 COG0583 LysR, Transcriptional regulator Transcription 119385538 Common - dephospho-CoA kinase Pden_2814 196 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 119383248 Nonpathogen - Hpt protein Pden_0496 6 None None None 119384558 Common - hypothetical protein Pden_1821 45 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 119384298 Common - Capsule polysaccharide biosynthesis Pden_1558 29 COG3562 KpsS, Capsule polysaccharide export protein Cell envelope biogenesis, outer membrane 119385241 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase Pden_2514 141 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 119384793 Common - DNA-cytosine methyltransferase Pden_2061 100 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 119383252 Common - 3-demethylubiquinone-9 3-methyltransferase Pden_0500 64 COG3865 COG3865, Uncharacterized protein conserved in bacteria Function unknown 119385416 Common - flavin reductase domain protein, FMN-binding Pden_2689 78 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 119384847 Common flgG flagellar basal body rod protein FlgG Pden_2115 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 119383186 Nonpathogen - aa3 type cytochrome c oxidase subunit IV Pden_0432 2 None None None 119384654 Common - fructose-bisphosphate aldolase Pden_1920 69 COG1830 FbaB, DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes Carbohydrate transport and metabolism 119383021 Common - Peptidoglycan-binding domain 1 protein Pden_0267 37 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 119384886 Common - protein of unknown function DUF421 Pden_2154 69 COG2323 COG2323, Predicted membrane protein Function unknown 119385471 Common - inner-membrane translocator Pden_2747 123 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 119384882 Common - binding-protein-dependent transport systems inner membrane component Pden_2150 196 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 119385276 Common - ATP--cobalamin adenosyltransferase Pden_2549 128 COG2096 COG2096, Uncharacterized conserved protein Function unknown 119385266 Nonpathogen - precorrin methylase Pden_2539 3 None None None 119383181 Nonpathogen - hypothetical protein Pden_0427 6 None None None 119383848 Common - major facilitator superfamily MFS_1 Pden_1100 65 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 119384410 Common - hypothetical protein Pden_1673 8 None None None 119383431 Common - Asp/Glu racemase Pden_0679 44 COG4126 COG4126, Hydantoin racemase Amino acid transport and metabolism 119384202 Common - GCN5-related N-acetyltransferase Pden_1462 67 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 119383264 Common - sarcosine oxidase, beta subunit family Pden_0512 127 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 119383216 Common - Recombinase Pden_0463 41 None None None 119385330 Common - putative PTS IIA-like nitrogen-regulatory protein PtsN Pden_2603 132 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 119383743 Nonpathogen - hypothetical protein Pden_0992 1 None None None 119384372 Common - superoxide dismutase, copper/zinc binding Pden_1634 87 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 119383660 Common - Sec-independent protein translocase, TatC subunit Pden_0909 204 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 119384959 Common trmB tRNA (guanine-N(7))-methyltransferase Pden_2227 172 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 119384688 Common - putative PAS/PAC sensor protein Pden_1956 5 None None None 119383118 Nonpathogen - hypothetical protein Pden_0364 2 None None None 119384266 Common - helicase domain protein Pden_1526 142 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 119382775 Common - GCN5-related N-acetyltransferase Pden_0018 55 COG0456 RimI, Acetyltransferases General function prediction only 119384379 Common - sulfoacetaldehyde acetyltransferase Pden_1642 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 119384055 Common - integral membrane sensor signal transduction histidine kinase Pden_1310 198 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 119384157 Common secD preprotein translocase subunit SecD Pden_1416 222 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 119382767 Common - ribonuclease PH Pden_0010 186 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 119383287 Nonpathogen - hypothetical protein Pden_0535 7 None None None 119385292 Common - putative esterase Pden_2565 32 COG2819 COG2819, Predicted hydrolase of the alpha/beta superfamily General function prediction only 119384694 Common - hypothetical protein Pden_1962 5 None None None 119383277 Common - inner-membrane translocator Pden_0525 122 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 119384630 Nonpathogen - protein of unknown function DUF177 Pden_1895 5 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 119382800 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Pden_0043 82 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 119384644 Common - protein of unknown function DUF1321 Pden_1909 40 COG3814 COG3814, Uncharacterized protein conserved in bacteria Function unknown 119384624 Common - MgtC/SapB transporter Pden_1889 119 COG1285 SapB, Uncharacterized membrane protein Function unknown 119384280 Nonpathogen - hypothetical protein Pden_1540 5 None None None 119384261 Common - hypothetical protein Pden_1521 3 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 119383918 Common - transcriptional regulator, LysR family Pden_1173 174 COG0583 LysR, Transcriptional regulator Transcription 119383562 Common - extracellular solute-binding protein, family 5 Pden_0810 209 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 119384637 Common - protein of unknown function DUF6, transmembrane Pden_1902 103 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 119383827 Common - extracellular solute-binding protein, family 1 Pden_1078 95 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 119384132 Common - BolA family protein Pden_1391 68 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 119384336 Common - ABC-3 protein Pden_1596 175 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 119384817 Common - hypothetical protein Pden_2085 36 COG2378 COG2378, Predicted transcriptional regulator Transcription 119383001 Common - periplasmic binding protein/LacI transcriptional regulator Pden_0247 110 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 119383147 Common - hypothetical protein Pden_0393 2 None None None 119384631 Common - choline dehydrogenase Pden_1896 94 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 119384042 Common - NAD-dependent epimerase/dehydratase Pden_1297 129 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 119382852 Common - Resolvase, N-terminal domain Pden_0095 128 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 119385453 Common - peptidase M23B Pden_2729 77 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 119384066 Common lysK lysyl-tRNA synthetase Pden_1321 77 COG1384 LysS, Lysyl-tRNA synthetase (class I) Translation, ribosomal structure and biogenesis 119384766 Nonpathogen - toluene tolerance family protein Pden_2034 5 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 119383098 Nonpathogen - hypothetical protein Pden_0344 1 None None None 119385189 Common - peptidase C14, caspase catalytic subunit p20 Pden_2462 19 COG4249 COG4249, Uncharacterized protein containing caspase domain General function prediction only 119384603 Common - putative transcriptional regulator Pden_1866 150 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 119384655 Common - signal recognition particle-docking protein FtsY Pden_1921 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 119383230 Common - protein of unknown function DUF1100, hydrolase family protein Pden_0478 65 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 119382842 Nonpathogen - hypothetical protein Pden_0085 1 None None None 119384731 Common - Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) Pden_1999 206 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 119383158 Common - AMP nucleosidase Pden_0404 54 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 119383091 Common - hypothetical protein Pden_0337 10 None None None 119384096 Common - hypothetical protein Pden_1354 24 None None None 119384311 Common - binding-protein-dependent transport systems inner membrane component Pden_1571 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 119384255 Common - hypothetical protein Pden_1515 5 None None None 119383813 Common - AraC-type transcriptional regulator domain protein Pden_1064 90 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 119385281 Common - dihydroorotase, multifunctional complex type Pden_2554 210 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 119383734 Common - phage/plasmid primase, P4 family Pden_0983 49 COG3378 COG3378, Predicted ATPase General function prediction only 119385322 Nonpathogen - hypothetical protein Pden_2595 2 None None None 119383524 Common rpsN 30S ribosomal protein S14 Pden_0772 204 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 119385370 Nonpathogen - hypothetical protein Pden_2643 1 None None None 119385286 Common - Auxin Efflux Carrier Pden_2559 129 COG0679 COG0679, Predicted permeases General function prediction only 119384016 Common - acetyl-CoA carboxylase biotin carboxylase subunit Pden_1271 224 COG0439 AccC, Biotin carboxylase Lipid metabolism 119384147 Common - ChaC family protein Pden_1406 44 COG3703 ChaC, Uncharacterized protein involved in cation transport Inorganic ion transport and metabolism 119382822 Nonpathogen - hypothetical protein Pden_0065 1 None None None 119384028 Common - 3-dehydroquinate synthase Pden_1283 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 119384049 Common - peptidase M19, renal dipeptidase Pden_1304 102 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 119384215 Common - conjugation TrbI family protein Pden_1475 58 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 119385108 Common - putative RNA methylase Pden_2378 130 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 119385172 Common - protein of unknown function DUF796 Pden_2445 31 COG3157 Hcp, Hemolysin-coregulated protein (uncharacterized) Function unknown 119382991 Common - binding-protein-dependent transport systems inner membrane component Pden_0237 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 119385481 Common - glycosyl transferase, family 25 Pden_2757 20 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 119385167 Common - ATPase AAA-2 domain protein Pden_2440 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 119385554 Common - molybdopterin oxidoreductase Fe4S4 region Pden_2830 171 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 119383035 Common - extracellular solute-binding protein, family 3 Pden_0281 104 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 119384950 Common - Sporulation domain protein Pden_2218 5 COG3147 DedD, Uncharacterized protein conserved in bacteria Function unknown 119385248 Nonpathogen - hypothetical protein Pden_2521 1 None None None 119384940 Common - thioredoxin reductase Pden_2208 245 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 119385264 Common - Precorrin-6A reductase Pden_2537 69 COG2099 CobK, Precorrin-6x reductase Coenzyme metabolism 119384094 Common - protein of unknown function DUF955 Pden_1350 45 COG3800 COG3800, Predicted transcriptional regulator General function prediction only 119383464 Common - N-formylglutamate amidohydrolase Pden_0712 55 COG3741 HutG, N-formylglutamate amidohydrolase Amino acid transport and metabolism 119384704 Common - Recombinase Pden_1972 76 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 119384039 Common - hypothetical protein Pden_1294 3 COG4421 COG4421, Capsular polysaccharide biosynthesis protein Carbohydrate transport and metabolism 119382940 Common - hypothetical protein Pden_0184 7 None None None 119384523 Common - response regulator receiver protein Pden_1786 215 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 119382961 Common - alpha/beta hydrolase fold Pden_0207 66 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 119384129 Common - transcriptional regulator, XRE family Pden_1388 42 COG1396 HipB, Predicted transcriptional regulators Transcription 119384069 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Pden_1324 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 119383537 Common rplQ 50S ribosomal protein L17 Pden_0785 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 119384815 Common - hypothetical protein Pden_2083 20 None None None 119385318 Common - hypothetical protein Pden_2591 178 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 119384762 Common - hypothetical protein Pden_2030 20 None None None 119382966 Common - heavy metal translocating P-type ATPase Pden_0212 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 119383559 Common - ErfK/YbiS/YcfS/YnhG family protein Pden_0807 80 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 119385544 Common - RNA polymerase sigma factor Pden_2820 108 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 119383223 Common - protein of unknown function DUF849 Pden_0471 63 COG3246 COG3246, Uncharacterized conserved protein Function unknown 119384287 Common - transcriptional regulator, XRE family Pden_1547 5 COG1396 HipB, Predicted transcriptional regulators Transcription 119383324 Common sdhB succinate dehydrogenase iron-sulfur subunit Pden_0572 195 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 119385516 Nonpathogen - hypothetical protein Pden_2792 2 None None None 119384785 Nonpathogen - hypothetical protein Pden_2053 1 None None None 119383969 Nonpathogen - hypothetical protein Pden_1224 1 None None None 119382911 Common - conjugal transfer protein TrbB Pden_0154 25 COG5268 TrbD, Type IV secretory pathway, TrbD component Cell motility and secretion / Intracellular trafficking and secretion 119383983 Common - protein of unknown function DUF882 Pden_1238 62 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 119385299 Common - Ribulose-phosphate 3-epimerase Pden_2572 215 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 119384972 Nonpathogen - hypothetical protein Pden_2240 4 None None None 119384490 Nonpathogen - hypothetical protein Pden_1753 4 None None None 119383996 Common - ABC transporter related Pden_1251 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 119384549 Common - PfkB domain protein Pden_1812 36 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 119384565 Common - helicase domain protein Pden_1828 64 COG4581 COG4581, Superfamily II RNA helicase DNA replication, recombination, and repair 119383908 Common - formate dehydrogenase Pden_1161 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 119384166 Common - ABC transporter related Pden_1425 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 119384908 Common - hypothetical protein Pden_2176 26 COG2981 CysZ, Uncharacterized protein involved in cysteine biosynthesis Amino acid transport and metabolism 119383375 Common - protein of unknown function DUF1127 Pden_0623 7 COG5457 COG5457, Uncharacterized conserved small protein Function unknown 119383120 Common - phage head-tail adaptor, putative Pden_0366 3 COG5614 COG5614, Bacteriophage head-tail adaptor General function prediction only 119384979 Common - NADH dehydrogenase subunit D Pden_2247 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 119383020 Nonpathogen - hypothetical protein Pden_0266 1 None None None 119385409 Common - S-adenosyl-L-homocysteine hydrolase Pden_2682 177 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 119382980 Common - luciferase family protein Pden_0226 103 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 119383956 Common - urease, gamma subunit Pden_1211 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 119383398 Common - Peptide deformylase Pden_0646 198 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 119383676 Common - protein of unknown function DUF6, transmembrane Pden_0925 59 COG2510 COG2510, Predicted membrane protein Function unknown 119384587 Common - putative transcriptional regulator, Crp/Fnr family Pden_1850 132 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 119384686 Common - SAM-dependent methyltransferase Pden_1954 104 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 119385085 Common - putative ABC transporter periplasmic solute-binding protein Pden_2355 12 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 119384845 Common - export protein FliQ, family 3 Pden_2113 120 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 119382947 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pden_0191 6 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 119383921 Common - catechol 1,2-dioxygenase Pden_1176 48 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 119385138 Common - hypothetical protein Pden_2410 9 None None None 119384323 Common mdoG glucan biosynthesis protein G Pden_1583 50 COG3131 MdoG, Periplasmic glucans biosynthesis protein Inorganic ion transport and metabolism 119384451 Common - inner-membrane translocator Pden_1714 151 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 119383885 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Pden_1137 152 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 119384933 Common - phosphoribosylaminoimidazole carboxylase, ATPase subunit Pden_2201 193 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 119385226 Common - putative translaldolase Pden_2499 155 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 119385447 Common - selenophosphate synthetase Pden_2723 114 COG0709 SelD, Selenophosphate synthase Amino acid transport and metabolism 119384102 Common - transport system permease protein Pden_1361 190 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 119384660 Nonpathogen - hypothetical protein Pden_1926 5 COG2900 SlyX, Uncharacterized protein conserved in bacteria Function unknown 119383332 Nonpathogen - protein of unknown function DUF1127 Pden_0580 4 COG5457 COG5457, Uncharacterized conserved small protein Function unknown 119383354 Nonpathogen - hypothetical protein Pden_0602 1 None None None 119384190 Common - hypothetical protein Pden_1449 33 COG3911 COG3911, Predicted ATPase General function prediction only 119384508 Common - integral membrane sensor signal transduction histidine kinase Pden_1771 187 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 119384199 Common - DSBA oxidoreductase Pden_1459 45 COG3917 NahD, 2-hydroxychromene-2-carboxylate isomerase Secondary metabolites biosynthesis, transport, and catabolism 119384773 Common - acetylornithine and succinylornithine aminotransferases Pden_2041 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 119382814 Common - band 7 protein Pden_0057 215 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 119384918 Nonpathogen - hypothetical protein Pden_2186 1 None None None 119384369 Common - TonB-dependent receptor, plug Pden_1631 123 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 119382923 Common - Cupin 2, conserved barrel domain protein Pden_0167 29 COG3435 COG3435, Gentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 119384359 Common - flagellin domain protein Pden_1620 93 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 119385025 Common - hypothetical protein Pden_2294 8 None None None 119384060 Common - glucosyltransferase MdoH Pden_1315 60 COG2943 MdoH, Membrane glycosyltransferase Cell envelope biogenesis, outer membrane 119382837 Common - PAS/PAC sensor hybrid histidine kinase Pden_0080 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 119383196 Nonpathogen - hypothetical protein Pden_0442 1 None None None 119383179 Common - Electron-transferring-flavoprotein dehydrogenase Pden_0425 110 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 119383029 Nonpathogen - hypothetical protein Pden_0275 1 None None None 119383455 Nonpathogen - hypothetical protein Pden_0703 1 None None None 119383504 Nonpathogen - hypothetical protein Pden_0752 3 None None None 119384859 Common - ABC transporter related Pden_2127 246 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 119384133 Common - glutaredoxin-like protein Pden_1392 127 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 119385193 Nonpathogen - hypothetical protein Pden_2466 1 None None None 119384396 Common - integral membrane sensor signal transduction histidine kinase Pden_1659 182 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 119383877 Nonpathogen - von Willebrand factor, type A Pden_1129 4 None None None 119384246 Common - TRAG family protein Pden_1506 76 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 119384863 Common - GCN5-related N-acetyltransferase Pden_2131 38 COG3153 COG3153, Predicted acetyltransferase General function prediction only 119383608 Common - Lysine exporter protein (LYSE/YGGA) Pden_0856 114 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 119383482 Common - ABC transporter related Pden_0730 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 119383978 Common - 2-dehydro-3-deoxyphosphooctonate aldolase Pden_1233 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 119385398 Common - Amidase Pden_2671 220 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 119384895 Common - Alcohol dehydrogenase GroES domain protein Pden_2163 208 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 119383991 Common - hypothetical protein Pden_1246 17 COG5463 COG5463, Predicted integral membrane protein Function unknown 119383577 Common - transglutaminase, N-terminal domain protein Pden_0825 86 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 119385001 Common - Alcohol dehydrogenase, zinc-binding domain protein Pden_2269 190 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 119384592 Common - ABC transporter related Pden_1855 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 119383250 Nonpathogen - hypothetical protein Pden_0498 1 None None None 119383665 Common - transcriptional regulator, MarR family Pden_0914 51 COG1846 MarR, Transcriptional regulators Transcription 119382933 Common - inner-membrane translocator Pden_0177 146 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 119382866 Common - AraC-type transcriptional regulator domain protein Pden_0109 74 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 119384924 Common - glycosyl transferase, group 1 Pden_2192 107 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 119384424 Common - transcriptional regulator, AraC family Pden_1687 158 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 119382873 Common - transferase hexapeptide repeat containing protein Pden_0116 161 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 119385456 Common - protein of unknown function DUF81 Pden_2732 39 COG0730 COG0730, Predicted permeases General function prediction only 119385034 Common - chaperone protein DnaJ Pden_2303 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 119385495 Common - 5'-nucleotidase, lipoprotein e(P4) family Pden_2771 24 COG2503 COG2503, Predicted secreted acid phosphatase General function prediction only 119384109 Common - TonB-dependent receptor Pden_1368 126 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 119383593 Nonpathogen - hypothetical protein Pden_0841 1 None None None 119385258 Common - cobalamin biosynthesis protein CobW Pden_2531 128 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 119384512 Common - TonB-dependent siderophore receptor Pden_1775 119 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 119384111 Nonpathogen - hypothetical protein Pden_1370 1 None None None 119383870 Common - protein of unknown function DUF336 Pden_1122 20 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 119384237 Common - helix-turn-helix- domain containing protein, AraC type Pden_1497 141 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 119384465 Common - CHAD domain containing protein Pden_1728 71 COG3025 COG3025, Uncharacterized conserved protein Function unknown 119385304 Common - (Uracil-5)-methyltransferase Pden_2577 155 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 119385355 Common flhA flagellar biosynthesis protein A Pden_2628 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 119384087 Common - binding-protein-dependent transport systems inner membrane component Pden_1342 217 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 119384542 Common - binding-protein-dependent transport systems inner membrane component Pden_1805 220 COG4239 COG4239, ABC-type uncharacterized transport system, permease component General function prediction only 119383547 Common - polar amino acid ABC transporter, inner membrane subunit Pden_0795 180 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 119385131 Common - transcriptional regulator, XRE family Pden_2403 48 COG1396 HipB, Predicted transcriptional regulators Transcription 119384477 Common - hypothetical protein Pden_1740 38 COG3750 COG3750, Uncharacterized protein conserved in bacteria Function unknown 119384305 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Pden_1565 68 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 119383567 Common - metallophosphoesterase Pden_0815 80 None None None 119384179 Common - pathogenesis-related protein Pden_1438 41 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 119384992 Nonpathogen - hypothetical protein Pden_2260 1 None None None 119384741 Common - sulfotransferase Pden_2009 26 None None None 119385017 Common - sulfatase Pden_2286 81 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 119382868 Common - hypothetical protein Pden_0111 2 None None None 119384878 Common - hydrolase, TatD family Pden_2146 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 119383293 Common - pyruvate phosphate dikinase Pden_0541 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 119383000 Common - Xylose isomerase domain protein TIM barrel Pden_0246 40 COG4952 COG4952, Predicted sugar isomerase Cell envelope biogenesis, outer membrane 119384723 Common - aldehyde dehydrogenase Pden_1991 219 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 119383442 Common - ATP-dependent metalloprotease FtsH Pden_0690 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 119383933 Common - ferredoxin Pden_1188 156 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 119382884 Common - hypothetical protein Pden_0127 12 None None None 119385224 Common - catalase/peroxidase HPI Pden_2497 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 119385529 Common - Lysine exporter protein (LYSE/YGGA) Pden_2805 111 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 119383408 Common - phosphoadenosine phosphosulfate reductase Pden_0656 160 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 119384813 Common - Recombinase Pden_2081 143 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 119385311 Common - SAM-dependent methyltransferase Pden_2584 59 None None None 119384716 Common - dihydroxy-acid dehydratase Pden_1984 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 119384293 Common - NusB antitermination factor Pden_1553 47 COG0781 NusB, Transcription termination factor Transcription 119385362 Common - hypothetical protein Pden_2635 8 None None None 119385014 Nonpathogen - Tetratricopeptide TPR_2 repeat protein Pden_2282 7 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 119383476 Common - transcriptional regulator, LysR family Pden_0724 189 COG0583 LysR, Transcriptional regulator Transcription 119383693 Common - putative transcriptional regulator, AsnC family Pden_0942 163 COG1522 Lrp, Transcriptional regulators Transcription 119384874 Common - LexA repressor Pden_2142 173 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 119384015 Common aat leucyl/phenylalanyl-tRNA--protein transferase Pden_1270 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 119385549 Common - selenocysteine-specific translation elongation factor Pden_2825 249 COG3276 SelB, Selenocysteine-specific translation elongation factor Translation, ribosomal structure and biogenesis 119383821 Common - extracellular solute-binding protein, family 3 Pden_1072 115 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 119383261 Common - protein of unknown function DUF1289 Pden_0509 37 COG3313 COG3313, Predicted Fe-S protein General function prediction only 119383412 Common - gamma-glutamyltransferase Pden_0660 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 119383623 Common - ribosomal protein L34 Pden_0872 190 COG0230 RpmH, Ribosomal protein L34 Translation, ribosomal structure and biogenesis 119383774 Common - binding-protein-dependent transport systems inner membrane component Pden_1023 218 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 119384351 Common - ABC transporter related Pden_1611 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 119383869 Common - transcriptional regulator, TetR family Pden_1121 41 COG1309 AcrR, Transcriptional regulator Transcription 119384929 Common - export-related chaperone CsaA Pden_2197 144 COG0073 ARC1, EMAP domain General function prediction only 119384460 Common - hypothetical protein Pden_1723 5 COG4907 COG4907, Predicted membrane protein Function unknown 119385116 Common - condensation domain protein Pden_2387 57 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 119383775 Common - ABC transporter related Pden_1024 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 119384222 Common - conjugal transfer protein trbB Pden_1482 24 COG5268 TrbD, Type IV secretory pathway, TrbD component Cell motility and secretion / Intracellular trafficking and secretion 119383351 Common - protein of unknown function DUF1330 Pden_0599 40 COG5470 COG5470, Uncharacterized conserved protein Function unknown 119383343 Nonpathogen - putative tellurite resistance protein Pden_0591 2 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 119384986 Common moaA molybdenum cofactor biosynthesis protein A Pden_2254 197 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 119383259 Common - chaperone DnaJ domain protein Pden_0507 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 119383984 Nonpathogen - hypothetical protein Pden_1239 1 None None None 119385423 Common - protein of unknown function DUF1078 domain protein Pden_2696 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 119383861 Common - allantoate amidohydrolase Pden_1113 84 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 119383892 Common - hypothetical protein Pden_1144 29 COG4321 COG4321, Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis General function prediction only 119384027 Common - Shikimate kinase Pden_1282 199 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 119383061 Common - putative tricarboxylic transport membrane protein Pden_0307 23 None None None 119383168 Common - putative metallo-phosphoesterase Pden_0414 43 COG1407 COG1407, Predicted ICC-like phosphoesterases General function prediction only 119384476 Common - ABC polyamine/opine transporter, periplasmic substrate-binding protein Pden_1739 33 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 119385039 Common - Ribokinase Pden_2308 140 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 119385210 Common - cytochrome c oxidase, subunit I Pden_2483 99 COG3256 NorB, Nitric oxide reductase large subunit Inorganic ion transport and metabolism 119383884 Common - protein of unknown function DUF892 Pden_1136 36 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 119385375 Nonpathogen - flagellar basal body-associated protein FliL Pden_2648 5 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 119384572 Common - protein of unknown function DUF344 Pden_1835 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 119384000 Common - 3-ketoacyl-(acyl-carrier-protein) reductase Pden_1255 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119384122 Common - Invasion associated locus B family protein Pden_1381 21 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 119384481 Common - thymidine kinase Pden_1744 70 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 119384470 Common - iron permease FTR1 Pden_1733 83 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 119384961 Common - pantothenate kinase Pden_2229 135 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 119383456 Common - dihydrodipicolinate synthase Pden_0704 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 119384824 Common - transposase, IS4 family protein Pden_2092 57 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 119384966 Common - NADH-ubiquinone oxidoreductase, chain 4L Pden_2234 151 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 119382874 Nonpathogen - hypothetical protein Pden_0117 2 None None None 119382840 Nonpathogen - hypothetical protein Pden_0083 1 None None None 119385353 Common flhB flagellar biosynthesis protein FlhB Pden_2626 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 119382811 Common - phenylacetate-CoA ligase, putative Pden_0054 95 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 119383659 Common - twin-arginine translocation protein, TatB subunit Pden_0908 17 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 119383899 Common - Arginase/agmatinase/formiminoglutamase Pden_1151 155 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 119382921 Common - transcriptional regulator, TetR family Pden_0164 21 COG1309 AcrR, Transcriptional regulator Transcription 119384983 Common - hypothetical protein Pden_2251 13 None None None 119382894 Common - Lytic transglycosylase, catalytic Pden_0137 153 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 119383573 Nonpathogen - hypothetical protein Pden_0821 1 None None None 119385403 Common - putative transport protein transmembrane Pden_2676 89 None None None 119384855 Nonpathogen - hypothetical protein Pden_2123 1 None None None 119383883 Common - hypothetical protein Pden_1135 5 None None None 119383589 Common - glycosyl transferase, family 2 Pden_0837 117 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 119383955 Common - HupE/UreJ protein Pden_1210 44 COG2370 HupE, Hydrogenase/urease accessory protein Posttranslational modification, protein turnover, chaperones 119384867 Nonpathogen - conserved hypothetical protein ZK84.1 Pden_2135 1 COG5373 COG5373, Predicted membrane protein Function unknown 119383952 Common - UreE urease accessory domain protein Pden_1207 64 COG2371 UreE, Urease accessory protein UreE Posttranslational modification, protein turnover, chaperones 119384564 Common - RNA-binding S4 domain protein Pden_1827 74 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 119383615 Common - ABC transporter related Pden_0864 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 119383972 Common - hypothetical protein Pden_1227 4 None None None 119384128 Common - inositol monophosphatase Pden_1387 178 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 119383086 Common - Glutathione S-transferase, N-terminal domain Pden_0332 81 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 119384927 Common - Hydroxypyruvate reductase Pden_2195 86 COG2379 GckA, Putative glycerate kinase Carbohydrate transport and metabolism 119383362 Common - amidohydrolase Pden_0610 166 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 119385228 Common xerC site-specific tyrosine recombinase XerC Pden_2501 222 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 119384343 Common - Dihydrolipoyllysine-residue succinyltransferase Pden_1603 194 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 119384578 Nonpathogen - cytochrome oxidase maturation protein, cbb3-type Pden_1841 5 COG3197 FixS, Uncharacterized protein, possibly involved in nitrogen fixation Inorganic ion transport and metabolism 119383459 Common - inositol monophosphatase Pden_0707 214 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 119384243 Common - hypothetical protein Pden_1503 38 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 119384871 Common - Indole-3-glycerol-phosphate synthase Pden_2139 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 119383793 Common - alpha/beta hydrolase fold Pden_1042 147 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 119383860 Common - dihydropyrimidinase Pden_1112 205 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 119382942 Common - amidohydrolase Pden_0186 169 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 119384474 Common - transcriptional regulator, LysR family Pden_1737 172 COG0583 LysR, Transcriptional regulator Transcription 119384217 Common - Conjugal transfer protein Pden_1477 34 COG3701 TrbF, Type IV secretory pathway, TrbF components Intracellular trafficking and secretion 119384861 Common - hypothetical protein Pden_2129 19 None None None 119384541 Common - ABC transporter related Pden_1804 249 COG4172 COG4172, ABC-type uncharacterized transport system, duplicated ATPase component General function prediction only 119383115 Common - peptidase S14, ClpP Pden_0361 40 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 119384037 Common - AMP-dependent synthetase and ligase Pden_1292 220 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 119384668 Common metH B12-dependent methionine synthase Pden_1935 177 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 119383342 Common - membrane protein involved in aromatic hydrocarbon degradation Pden_0590 19 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 119384193 Nonpathogen - DNA polymerase, beta-like Pden_1453 2 None None None 119385306 Common - Glutathione S-transferase, N-terminal domain Pden_2579 86 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 119385488 Common - hypothetical protein Pden_2764 22 None None None 119383915 Common - ABC transporter related Pden_1170 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 119384833 Common - DNA methylase N-4/N-6 domain protein Pden_2101 139 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 119385012 Nonpathogen - hypothetical protein Pden_2280 1 None None None 119383289 Nonpathogen - Peptidoglycan-binding domain 1 protein Pden_0537 6 None None None 119385524 Common - hypothetical protein Pden_2800 22 COG3698 COG3698, Predicted periplasmic protein Function unknown 119383937 Common - NADP oxidoreductase, coenzyme F420-dependent Pden_1192 124 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 119383437 Common - TolA family protein Pden_0685 9 COG2268 COG2268, Uncharacterized protein conserved in bacteria Function unknown 119384706 Common - Mu-like prophage major head subunit gpT Pden_1974 3 COG4397 COG4397, Mu-like prophage major head subunit gpT General function prediction only 119384235 Common - TonB-dependent receptor Pden_1495 116 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 119383934 Common - Rieske (2Fe-2S) domain protein Pden_1189 82 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 119383410 Common - Ferredoxin--NADP(+) reductase Pden_0658 106 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 119383820 Common - aminotransferase, class V Pden_1071 237 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 119384304 Common - TRAP dicarboxylate transporter, DctM subunit Pden_1564 129 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 119383388 Common - hypothetical protein Pden_0636 110 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 119383928 Common - transcriptional regulator, GntR family Pden_1183 136 COG1802 GntR, Transcriptional regulators Transcription 119385040 Common - peptidase S49 Pden_2309 187 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 119384088 Common - binding-protein-dependent transport systems inner membrane component Pden_1343 202 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 119383816 Common - OsmC family protein Pden_1067 88 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 119385201 Common - ATPase, BadF/BadG/BcrA/BcrD type Pden_2474 31 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 119383940 Common - Substrate-binding region of ABC-type glycine betaine transport system Pden_1195 29 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 119383282 Common - peptidase M22, glycoprotease Pden_0530 168 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 119383369 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Pden_0617 135 COG0546 Gph, Predicted phosphatases General function prediction only 119384875 Common - Serine-type D-Ala-D-Ala carboxypeptidase Pden_2143 153 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 119383609 Common - enoyl-(acyl carrier protein) reductase Pden_0857 229 COG0623 FabI, Enoyl- acyl-carrier-protein 119385026 Common - glycosyl transferase, group 1 Pden_2295 88 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 119384373 Common - signal transduction histidine kinase Pden_1635 63 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 119383578 Common - 20S proteasome, A and B subunits Pden_0826 54 COG3484 COG3484, Predicted proteasome-type protease Posttranslational modification, protein turnover, chaperones 119383227 Nonpathogen - hypothetical protein Pden_0475 1 None None None 119384788 Nonpathogen - hypothetical protein Pden_2056 1 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 119385432 Common - NLP/P60 protein Pden_2708 53 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 119384840 Common - putative transcriptional regulator, Crp/Fnr family Pden_2108 24 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 119383825 Common - protein of unknown function DUF1697 Pden_1076 44 COG3797 COG3797, Uncharacterized protein conserved in bacteria Function unknown 119384922 Nonpathogen - hypothetical protein Pden_2190 1 None None None 119384936 Nonpathogen - hypothetical protein Pden_2204 2 None None None 119385368 Nonpathogen - hypothetical protein Pden_2641 1 None None None 119384598 Common - 3-oxoacyl-(acyl-carrier-protein) synthase III Pden_1861 202 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 119385181 Common - hypothetical protein Pden_2454 16 COG3913 SciT, Uncharacterized protein conserved in bacteria Function unknown 119383418 Common - amino acid carrier protein Pden_0666 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 119384419 Common - inner-membrane translocator Pden_1682 115 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 119384965 Common - NADH dehydrogenase subunit L Pden_2233 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 119383295 Common - dihydroneopterin aldolase Pden_0543 42 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 119384108 Common - periplasmic binding protein Pden_1367 43 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 119383688 Common - protein of unknown function DUF339 Pden_0937 29 COG2938 COG2938, Uncharacterized conserved protein Function unknown 119383057 Common - transmembrane pair domain protein Pden_0303 41 COG4125 COG4125, Predicted membrane protein Function unknown 119384584 Common - cytochrome c oxidase, cbb3-type, subunit II Pden_1847 82 COG2993 CcoO, Cbb3-type cytochrome oxidase, cytochrome c subunit Energy production and conversion 119382798 Common - FAD dependent oxidoreductase Pden_0041 85 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 119385004 Common - cytochrome P450 Pden_2272 74 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 119383906 Nonpathogen - hypothetical protein Pden_1159 2 None None None 119383697 Common - binding-protein-dependent transport systems inner membrane component Pden_0946 219 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 119383555 Common - protein of unknown function DUF894, DitE Pden_0803 114 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 119384548 Common - 5'-Nucleotidase domain protein Pden_1811 92 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 119382914 Common - transcriptional regulator, LysR family Pden_0157 189 COG0583 LysR, Transcriptional regulator Transcription 119382865 Common - aldo/keto reductase Pden_0108 204 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 119385115 Common entE enterobactin synthase subunit E Pden_2386 221 COG1021 EntE, Peptide arylation enzymes Secondary metabolites biosynthesis, transport, and catabolism 119383985 Common - Peptidoglycan-binding domain 1 protein Pden_1240 74 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 119383195 Common - protein of unknown function DUF6, transmembrane Pden_0441 70 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 119383124 Nonpathogen - hypothetical protein Pden_0370 1 None None None 119384001 Common - ABC-3 protein Pden_1256 191 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 119383635 Common gltX glutamyl-tRNA synthetase Pden_0884 248 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 119385408 Nonpathogen - hypothetical protein Pden_2681 1 None None None 119383890 Common - ABC transporter related Pden_1142 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 119384008 Common - hypothetical protein Pden_1263 20 COG4427 COG4427, Uncharacterized protein conserved in bacteria Function unknown 119385354 Common - flagellar biosynthetic protein FliR Pden_2627 14 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 119383904 Common - periplasmic binding protein Pden_1157 16 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 119385251 Common - hypothetical protein Pden_2524 8 None None None 119382807 Common - inner-membrane translocator Pden_0050 146 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 119383675 Common - OsmC family protein Pden_0924 79 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 119382824 Common - IS66 Orf2 family protein Pden_0067 48 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 119383331 Common - protein of unknown function DUF519 Pden_0579 85 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 119382883 Nonpathogen - hypothetical protein Pden_0126 2 None None None 119383762 Common - major facilitator superfamily MFS_1 Pden_1011 216 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 119384245 Common - hypothetical protein Pden_1505 23 None None None 119384601 Common - putative transcriptional regulator, MerR family Pden_1864 92 COG0789 SoxR, Predicted transcriptional regulators Transcription 119385530 Common - glutathione-dependent formaldehyde-activating, GFA Pden_2806 65 COG3791 COG3791, Uncharacterized conserved protein Function unknown 119383241 Nonpathogen - hypothetical protein Pden_0489 3 None None None 119384780 Nonpathogen - hypothetical protein Pden_2048 1 None None None 119384608 Common - S-adenosylmethionine synthetase Pden_1873 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 119385008 Common - Pyruvate kinase Pden_2276 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 119384289 Nonpathogen - hypothetical protein Pden_1549 6 None None None 119384026 Nonpathogen - hypothetical protein Pden_1281 1 None None None 119384326 Common - integral membrane sensor signal transduction histidine kinase Pden_1586 198 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 119383886 Common - helix-turn-helix- domain containing protein, AraC type Pden_1138 120 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 119382809 Common - transcriptional regulator, Fis family Pden_0052 41 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 119383694 Common - bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase Pden_0943 221 COG4230 COG4230, Delta 1-pyrroline-5-carboxylate dehydrogenase Energy production and conversion 119385506 Common - histone family protein nucleoid-structuring protein H-NS Pden_2782 23 COG2916 Hns, DNA-binding protein H-NS General function prediction only 119383466 Common - Butyryl-CoA dehydrogenase Pden_0714 164 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 119384188 Common - PEBP family protein Pden_1447 124 COG1881 COG1881, Phospholipid-binding protein General function prediction only 119383374 Common - ribosomal L11 methyltransferase Pden_0622 175 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 119385018 Common - membrane protein of uknown function UCP014873 Pden_2287 25 COG4803 COG4803, Predicted membrane protein Function unknown 119383580 Common - hydratase/decarboxylase Pden_0828 56 COG3971 COG3971, 2-keto-4-pentenoate hydratase Secondary metabolites biosynthesis, transport, and catabolism 119385274 Common - short-chain dehydrogenase/reductase SDR Pden_2547 236 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 119383372 Common - peptidase S58, DmpA Pden_0620 54 COG3191 DmpA, L-aminopeptidase/D-esterase Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 119383355 Common - adenylosuccinate synthetase Pden_0603 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 119383023 Common - hypothetical protein Pden_0269 23 None None None 119385547 Common - 2-nitropropane dioxygenase, NPD Pden_2823 76 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 119384030 Common - putative monovalent cation/H+ antiporter subunit F Pden_1285 48 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 119384825 Common - 3-deoxy-D-manno-octulosonic-acid transferase-like Pden_2093 66 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 119385256 Common - cob(I)yrinic acid a,c-diamide adenosyltransferase Pden_2529 141 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 119384713 Common - GCN5-related N-acetyltransferase Pden_1981 21 COG0456 RimI, Acetyltransferases General function prediction only 119383175 Common acpS 4'-phosphopantetheinyl transferase Pden_0421 158 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 119384619 Common hisH imidazole glycerol phosphate synthase subunit HisH Pden_1884 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 119385216 Common - cytochrome c (c55X) Pden_2489 16 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 119384521 Common - two component transcriptional regulator, LuxR family Pden_1784 167 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 119383535 Common - 30S ribosomal protein S11 Pden_0783 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 119382983 Nonpathogen - Xylose isomerase domain protein TIM barrel Pden_0229 2 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 119385517 Common - thioredoxin Pden_2793 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 119385151 Common - RarD protein, DMT superfamily transporter Pden_2424 95 COG2962 RarD, Predicted permeases General function prediction only 119383672 Common ppnK inorganic polyphosphate/ATP-NAD kinase Pden_0921 230 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 119383702 Common - ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent Pden_0951 223 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 119384756 Common - DNA-3-methyladenine glycosylase I Pden_2024 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 119385399 Common - aminotransferase, class I and II Pden_2672 229 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 119383611 Common - putative cold-shock DNA-binding domain protein Pden_0859 142 COG1278 CspC, Cold shock proteins Transcription 119383622 Common - integral membrane sensor signal transduction histidine kinase Pden_0871 198 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 119383477 Common - TonB family protein Pden_0725 13 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 119383390 Common - hypothetical protein Pden_0638 40 COG3768 COG3768, Predicted membrane protein Function unknown 119384140 Common - hypothetical protein Pden_1399 29 COG3216 COG3216, Uncharacterized protein conserved in bacteria Function unknown 119384389 Common - hydrolase or acyltransferase Pden_1652 120 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 119385390 Common - beta-ketothiolase Pden_2663 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 119385317 Common - proline iminopeptidase Pden_2590 121 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 119384431 Common - transcriptional regulator, LysR family Pden_1694 141 COG0583 LysR, Transcriptional regulator Transcription 119385343 Common - hypothetical protein Pden_2616 8 None None None 119383251 Common - argininosuccinate synthase Pden_0499 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 119384454 Common - ABC branched-chain amino acid transporter, periplasmic binding protein Pden_1717 93 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 119384040 Common - lipase/acylhydrolase, putative Pden_1295 12 None None None 119384503 Common - basic membrane lipoprotein Pden_1766 77 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 119384665 Common - protein of unknown function DUF541 Pden_1932 73 COG2968 COG2968, Uncharacterized conserved protein Function unknown 119384258 Common - protein of unknown function DUF736 Pden_1518 27 COG5489 COG5489, Uncharacterized conserved protein Function unknown 119384338 Common - hypothetical protein Pden_1598 16 None None None 119383421 Common - 3-oxoacyl-(acyl-carrier-protein) synthase Pden_0669 192 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 119382913 Common - type II secretion system protein E Pden_0156 150 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 119383104 Nonpathogen - hypothetical protein Pden_0350 1 None None None 119384316 Common lysK lysyl-tRNA synthetase Pden_1576 77 COG1384 LysS, Lysyl-tRNA synthetase (class I) Translation, ribosomal structure and biogenesis 119385323 Common - mutator MutT protein Pden_2596 160 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 119382996 Common - iron-containing alcohol dehydrogenase Pden_0242 166 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 119384890 Common - inner-membrane translocator Pden_2158 114 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 119383422 Common - NAD-dependent epimerase/dehydratase Pden_0670 178 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 119385083 Common - domain of unknown function DUF1745 Pden_2353 28 COG3287 COG3287, Uncharacterized conserved protein Function unknown 119384186 Nonpathogen - hypothetical protein Pden_1445 1 None None None 119382985 Common - transcriptional regulator, LysR family Pden_0231 185 COG0583 LysR, Transcriptional regulator Transcription 119383832 Common - beta-lactamase Pden_1083 58 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 119385112 Common - isochorismate synthases Pden_2382 218 COG1169 MenF, Isochorismate synthase Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism 119384046 Common - hypothetical protein Pden_1301 102 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 119384013 Common - Mammalian cell entry related domain protein Pden_1268 55 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 119385126 Common - hypothetical protein Pden_2398 42 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 119382979 Common - flavin reductase domain protein, FMN-binding Pden_0225 16 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 119384734 Common - lipid A ABC exporter family, fused ATPase and inner membrane subunits Pden_2002 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 119384211 Common - transcriptional regulator, LysR family Pden_1471 188 COG0583 LysR, Transcriptional regulator Transcription 119385127 Nonpathogen - hypothetical protein Pden_2399 1 None None None 119385320 Common - hypothetical protein Pden_2593 45 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 119384636 Common - ABC transporter related Pden_1901 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 119383232 Common - major facilitator superfamily MFS_1 Pden_0480 78 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 119382760 Common - tRNA modification GTPase TrmE Pden_0003 217 COG0486 ThdF, Predicted GTPase General function prediction only 119385106 Common - hypothetical protein Pden_2376 40 COG3786 COG3786, Uncharacterized protein conserved in bacteria Function unknown 119383837 Common - binding-protein-dependent transport systems inner membrane component Pden_1089 155 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 119385166 Common - hypothetical protein Pden_2439 22 COG5351 COG5351, Uncharacterized protein conserved in bacteria Function unknown 119383019 Common - transcriptional regulator, XRE family Pden_0265 31 COG5499 COG5499, Predicted transcription regulator containing HTH domain Transcription 119385401 Common - hypothetical protein Pden_2674 34 COG2819 COG2819, Predicted hydrolase of the alpha/beta superfamily General function prediction only 119384218 Common - TrbL/VirB6 plasmid conjugal transfer protein Pden_1478 37 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 119385463 Common - LrgA family protein Pden_2739 10 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 119384764 Common - ammonium transporter Pden_2032 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 119383987 Nonpathogen - phosphopantetheine-binding Pden_1242 7 None None None 119383704 Common - AMP-dependent synthetase and ligase Pden_0953 221 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 119385458 Common - protein of unknown function DUF482 Pden_2734 82 COG3146 COG3146, Uncharacterized protein conserved in bacteria Function unknown 119382781 Common - hypothetical protein Pden_0024 17 None None None 119383629 Nonpathogen - MOSC domain containing protein Pden_0878 23 COG3217 COG3217, Uncharacterized Fe-S protein General function prediction only 119383620 Common - hypothetical protein Pden_0869 19 None None None 119383714 Common - hypothetical protein Pden_0963 10 None None None 119384003 Common - ABC transporter related Pden_1258 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 119382955 Common - 3-hydroxyacyl-CoA dehydrogenase, NAD-binding Pden_0201 162 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 119383709 Common - poly(R)-hydroxyalkanoic acid synthase, class I Pden_0958 73 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 119385105 Common - GTP cyclohydrolase II Pden_2375 185 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 119382899 Common - TRAG family protein Pden_0142 79 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 119385050 Common - 5,10-methylenetetrahydrofolate reductase Pden_2319 141 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 119384135 Common - protein of unknown function DUF883, ElaB Pden_1394 4 COG4575 ElaB, Uncharacterized conserved protein Function unknown 119383272 Common - lipolytic enzyme, G-D-S-L family Pden_0520 99 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 119384429 Common - creatinase Pden_1692 128 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 119385095 Common - transcriptional regulator, Fis family Pden_2365 79 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 119383204 Common - hypothetical protein Pden_0450 3 None None None 119384760 Common - protein of unknown function DUF465 Pden_2028 20 COG5570 COG5570, Uncharacterized small protein Function unknown 119384209 Common - putative transcriptional regulator, AsnC family Pden_1469 143 COG1522 Lrp, Transcriptional regulators Transcription 119383795 Common - glucose-methanol-choline oxidoreductase Pden_1044 92 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 119384416 Common - Xylose isomerase domain protein TIM barrel Pden_1679 37 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 119384696 Common - hypothetical protein Pden_1964 20 COG2253 COG2253, Uncharacterized conserved protein Function unknown 119384651 Common - peptidyl-prolyl cis-trans isomerase, cyclophilin type Pden_1917 198 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 119384735 Common - Allergen V5/Tpx-1 family protein Pden_2003 26 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 119382853 Common - hypothetical protein Pden_0096 16 COG2388 COG2388, Predicted acetyltransferase General function prediction only 119384253 Common - hypothetical protein Pden_1513 24 None None None 119383405 Common - putative transcriptional regulator, AsnC family Pden_0653 138 COG1522 Lrp, Transcriptional regulators Transcription 119383055 Common - L-seryl-tRNA(Sec) selenium transferase Pden_0301 65 COG1921 SelA, Selenocysteine synthase [seryl-tRNASer selenium transferase] Amino acid transport and metabolism 119382758 Common - conserved hypothetical protein 701 Pden_0001 89 COG1981 COG1981, Predicted membrane protein Function unknown 119385267 Common - precorrin-4 C11-methyltransferase Pden_2540 200 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 119383682 Common - extracellular solute-binding protein, family 5 Pden_0931 158 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 119384395 Common - pantoate--beta-alanine ligase Pden_1658 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 119384438 Common - AAA ATPase, central domain protein Pden_1701 48 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 119384809 Nonpathogen - hypothetical protein Pden_2077 1 None None None 119385173 Common - protein of unknown function DUF1316 Pden_2446 7 COG3518 COG3518, Uncharacterized protein conserved in bacteria Function unknown 119384162 Common - phage integrase family protein Pden_1421 77 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 119383487 Common - Carboxymethylenebutenolidase Pden_0735 117 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 119383461 Common - N-formimino-L-glutamate deiminase Pden_0709 118 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 119383200 Common - zinc finger, CHC2-family protein Pden_0446 139 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 119383519 Common - ribosomal protein L29 Pden_0767 131 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 119383720 Common - DNA methylase N-4/N-6 domain protein Pden_0969 4 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 119384957 Common - AMP-dependent synthetase and ligase Pden_2225 217 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 119382763 Common - Cobyrinic acid a,c-diamide synthase Pden_0006 239 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 119383312 Common - Hemolysin-type calcium-binding region Pden_0560 87 None None None 119383744 Nonpathogen - hypothetical protein Pden_0993 2 None None None 119384994 Common pheT phenylalanyl-tRNA synthetase subunit beta Pden_2262 222 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 119385113 Common - Isochorismatase Pden_2383 100 COG1535 EntB, Isochorismate hydrolase Secondary metabolites biosynthesis, transport, and catabolism 119384751 Common - hypothetical protein Pden_2019 30 COG5283 COG5283, Phage-related tail protein Function unknown 119383513 Common rplW 50S ribosomal protein L23 Pden_0761 224 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 119384897 Common - carbamoyl phosphate synthase small subunit Pden_2165 235 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 119384674 Common - Glyoxylate reductase Pden_1941 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 119384684 Common - glucose-6-phosphate 1-dehydrogenase Pden_1952 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 119383781 Common - major facilitator superfamily MFS_1 Pden_1030 61 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 119383719 Common - hypothetical protein Pden_0968 3 None None None 119384792 Common - HNH endonuclease Pden_2060 27 COG3183 COG3183, Predicted restriction endonuclease Defense mechanisms 119384192 Common - protein of unknown function DUF1330 Pden_1452 19 COG5470 COG5470, Uncharacterized conserved protein Function unknown 119383493 Common - preprotein translocase, SecE subunit Pden_0741 45 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 119383917 Common - TOBE domain protein Pden_1172 72 COG3585 MopI, Molybdopterin-binding protein Coenzyme metabolism 119384083 Common - cobalamin synthesis protein, P47K Pden_1338 129 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 119383430 Common - permease for cytosine/purines, uracil, thiamine, allantoin Pden_0678 76 COG1953 FUI1, Cytosine/uracil/thiamine/allantoin permeases Nucleotide transport and metabolism / Coenzyme metabolism 119383926 Common - major facilitator superfamily MFS_1 Pden_1181 118 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 119385055 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Pden_2324 237 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 119383075 Common - hypothetical protein Pden_0321 41 COG4336 COG4336, Uncharacterized conserved protein Function unknown 119385199 Common - extracellular solute-binding protein, family 1 Pden_2472 66 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 119384513 Common - helix-turn-helix- domain containing protein, AraC type Pden_1776 7 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 119383046 Common - protein of unknown function DUF1006 Pden_0292 60 COG3214 COG3214, Uncharacterized protein conserved in bacteria Function unknown 119385247 Common - isopropylmalate isomerase large subunit Pden_2520 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 119382939 Common - D-amino acid dehydrogenase small subunit Pden_0183 104 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 119384200 Common - GCN5-related N-acetyltransferase Pden_1460 53 COG0456 RimI, Acetyltransferases General function prediction only 119384880 Common - Auxin Efflux Carrier Pden_2148 48 COG0679 COG0679, Predicted permeases General function prediction only 119384528 Common - maf protein Pden_1791 197 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 119383280 Common - basic membrane lipoprotein Pden_0528 105 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 119385522 Common - dihydrodipicolinate reductase Pden_2798 216 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 119384942 Nonpathogen - hypothetical protein Pden_2210 1 None None None 119383095 Common - DNA methylase N-4/N-6 domain protein Pden_0341 5 None None None 119384968 Common - Carboxymuconolactone decarboxylase Pden_2236 58 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 119385378 Common - surface presentation of antigens (SPOA) protein Pden_2651 10 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 119384556 Common - DSBA oxidoreductase Pden_1819 102 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 119383013 Nonpathogen - hypothetical protein Pden_0259 1 None None None 119383138 Nonpathogen - hypothetical protein Pden_0384 1 None None None 119384857 Common - ABC-2 type transporter Pden_2125 34 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 119385089 Common - pyrroloquinoline quinone biosynthesis protein PqqE Pden_2359 137 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 119383140 Common - protein of unknown function DUF159 Pden_0386 103 COG2135 COG2135, Uncharacterized conserved protein Function unknown 119385077 Common - glycine cleavage system H protein Pden_2347 183 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 119383756 Nonpathogen - hypothetical protein Pden_1005 1 None None None 119384282 Common - DNA repair protein RadC Pden_1542 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 119383149 Common - Diaminopimelate epimerase Pden_0395 200 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 119382816 Common - Glutathione S-transferase, N-terminal domain Pden_0059 62 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 119383851 Common - major facilitator superfamily MFS_1 Pden_1103 135 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 119385445 Common - efflux transporter, RND family, MFP subunit Pden_2721 131 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 119384356 Common - transposase IS3/IS911 family protein Pden_1617 47 None None None 119382858 Nonpathogen - hypothetical protein Pden_0101 1 None None None 119383133 Nonpathogen - hypothetical protein Pden_0379 1 None None None 119383184 Nonpathogen - branched-chain amino acid transport Pden_0430 10 COG4392 COG4392, Predicted membrane protein Function unknown 119385371 Common - phage integrase family protein Pden_2644 25 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 119383725 Nonpathogen - hypothetical protein Pden_0974 1 None None None 119384401 Common - 4-hydroxyphenylpyruvate dioxygenase Pden_1664 76 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 119384799 Nonpathogen - hypothetical protein Pden_2067 4 None None None 119383319 Common - succinate dehydrogenase, cytochrome b subunit Pden_0567 91 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 119384382 Common - TRAP dicarboxylate transporter, DctM subunit Pden_1645 134 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 119383154 Common - 1-deoxy-D-xylulose-5-phosphate synthase Pden_0400 227 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 119383545 Common - cationic amino acid ABC transporter, periplasmic binding protein Pden_0793 115 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 119385145 Common - IS66 Orf2 family protein Pden_2417 33 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 119384771 Common - ornithine carbamoyltransferase Pden_2039 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 119382970 Common - protein tyrosine phosphatase Pden_0216 114 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 119384079 Common - hypothetical protein Pden_1334 5 None None None 119383910 Common - NUDIX hydrolase Pden_1163 67 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 119383303 Common - dihydrolipoamide dehydrogenase Pden_0551 245 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 119383527 Common rplR 50S ribosomal protein L18 Pden_0775 214 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 119383334 Common - hypothetical protein Pden_0582 101 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 119383663 Nonpathogen - hypothetical protein Pden_0912 1 None None None 119384141 Common - (p)ppGpp synthetase I, SpoT/RelA Pden_1400 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 119385231 Common - hypothetical protein Pden_2504 29 None None None 119384422 Common - regulatory protein, LacI Pden_1685 35 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 119385279 Common - 3-hydroxybutyryl-CoA dehydrogenase Pden_2552 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 119385240 Common - Transglycosylase-associated protein Pden_2513 12 COG2261 COG2261, Predicted membrane protein Function unknown 119384679 Common - deoxyuridine 5'-triphosphate nucleotidohydrolase Dut Pden_1946 185 COG0756 Dut, dUTPase Nucleotide transport and metabolism 119383439 Common - OmpA domain protein Pden_0687 154 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 119383326 Common - beta-lactamase domain protein Pden_0574 86 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 119385470 Common - ABC transporter related Pden_2746 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 119384566 Common - TPR repeat-containing protein Pden_1829 30 COG5373 COG5373, Predicted membrane protein Function unknown 119384616 Common - protein of unknown function DUF710 Pden_1881 18 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 119385071 Common - molybdopterin biosynthesis MoaE Pden_2340 131 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 119385331 Common - sigma 54 modulation protein/ribosomal protein S30EA Pden_2604 104 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 119383244 Common - NAD-dependent epimerase/dehydratase Pden_0492 104 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 119385551 Common - formate dehydrogenase, gamma subunit Pden_2827 48 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 119384457 Common - Malonyl-CoA decarboxylase Pden_1720 29 None None None 119383117 Nonpathogen - hypothetical protein Pden_0363 1 None None None 119383780 Nonpathogen - hypothetical protein Pden_1029 1 None None None 119383847 Common - Xylose isomerase domain protein TIM barrel Pden_1099 26 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 119383030 Common - conserved hypothetical sugar-binding protein Pden_0276 100 COG1609 PurR, Transcriptional regulators Transcription 119384901 Common - acetolactate synthase 3 catalytic subunit Pden_2169 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 119383733 Nonpathogen - hypothetical protein Pden_0982 1 None None None 119383633 Common - PfkB domain protein Pden_0882 87 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 119384533 Common - GCN5-related N-acetyltransferase Pden_1796 60 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 119383787 Common - amidohydrolase 2 Pden_1036 48 COG3618 COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 119383806 Common - deaminase Pden_1057 69 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 119385272 Common - cytochrome B561 Pden_2545 47 COG3658 COG3658, Cytochrome b Energy production and conversion 119385412 Common - Enoyl-CoA hydratase/isomerase Pden_2685 167 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 119384906 Nonpathogen - protein of unknown function DUF167 Pden_2174 4 COG1872 COG1872, Uncharacterized conserved protein Function unknown 119384177 Common - MOSC domain containing protein Pden_1436 79 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 119383404 Common - histidinol-phosphate aminotransferase Pden_0652 232 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 119384158 Common - preprotein translocase, YajC subunit Pden_1417 177 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 119384057 Nonpathogen - hypothetical protein Pden_1312 1 COG3212 COG3212, Predicted membrane protein Function unknown 119383161 Common - glutathione S-transferase Pden_0407 65 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 119382931 Common - putative ABC transporter binding protein Pden_0175 122 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 119383596 Common - glycosyl transferase, family 2 Pden_0844 12 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 119383638 Common tig trigger factor Pden_0887 213 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 119384297 Common - riboflavin synthase subunit alpha Pden_1557 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 119384744 Nonpathogen - hypothetical protein Pden_2012 1 None None None 119384807 Common - PilT protein domain protein Pden_2075 47 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 119385203 Common - Glutamine--fructose-6-phosphate transaminase (isomerizing) Pden_2476 233 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 119385508 Common - preprotein translocase subunit SecB Pden_2784 108 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 119383721 Common - DNA polymerase III, beta subunit Pden_0970 196 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 119383932 Common - Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein Pden_1187 69 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 119385380 Common - efflux transporter, RND family, MFP subunit Pden_2653 132 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 119384970 Common - NADH dehydrogenase subunit I Pden_2238 194 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 119383988 Common - beta-ketoacyl synthase Pden_1243 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 119383416 Common - TRAP transporter solute receptor, TAXI family Pden_0664 86 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 119384865 Common - putative peptidyl-prolyl cis-trans isomerse Pden_2133 101 None None None 119384480 Common - DEAD/DEAH box helicase domain protein Pden_1743 235 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 119383889 Common - iron-hydroxamate transporter permease subunit Pden_1141 74 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 119383995 Common - binding-protein-dependent transport systems inner membrane component Pden_1250 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 119385459 Common - glycerophosphoryl diester phosphodiesterase Pden_2735 87 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 119384123 Common - protease Do Pden_1382 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 119383336 Common - hypothetical protein Pden_0584 10 COG5462 COG5462, Predicted secreted (periplasmic) protein Function unknown 119383777 Common - polar amino acid ABC transporter, inner membrane subunit Pden_1026 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 119383866 Common - F420-dependent oxidoreductase, putative Pden_1118 43 COG1478 COG1478, Uncharacterized conserved protein Function unknown 119383909 Common - Arginase/agmatinase/formiminoglutamase Pden_1162 15 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 119384721 Common - AFG1-family ATPase Pden_1989 103 COG1485 COG1485, Predicted ATPase General function prediction only 119385308 Common - ErfK/YbiS/YcfS/YnhG family protein Pden_2581 84 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 119385429 Common - Carbonate dehydratase Pden_2705 149 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 119384591 Nonpathogen - hypothetical protein Pden_1854 13 COG4391 COG4391, Uncharacterized protein conserved in bacteria Function unknown 119384689 Common - protein tyrosine phosphatase Pden_1957 77 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 119385090 Common - coenzyme PQQ synthesis D Pden_2360 20 None None None 119384663 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B Pden_1929 212 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 119385461 Nonpathogen - hypothetical protein Pden_2737 6 None None None 119383935 Common - transcriptional regulator, LysR family Pden_1190 151 COG0583 LysR, Transcriptional regulator Transcription 119384831 Nonpathogen - hypothetical protein Pden_2099 1 None None None 119383257 Common - periplasmic binding protein/LacI transcriptional regulator Pden_0505 86 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 119384417 Common - oxidoreductase domain protein Pden_1680 94 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 119384440 Common - quinohemoprotein amine dehydrogenase, 60 kDa subunit Pden_1703 5 None None None 119384393 Common argC N-acetyl-gamma-glutamyl-phosphate reductase Pden_1656 207 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 119383449 Common - putative monovalent cation/H+ antiporter subunit A Pden_0697 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 119384596 Common rpmF 50S ribosomal protein L32 Pden_1859 26 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 119383297 Common - phosphoglucosamine mutase Pden_0545 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 119384233 Common - ABC transporter related Pden_1493 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 119385061 Common - Glutathione S-transferase, N-terminal domain Pden_2330 101 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 119384860 Common - protein of unknown function DUF1486 Pden_2128 17 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 119385366 Nonpathogen - hypothetical protein Pden_2639 3 None None None 119384776 Common - NUDIX hydrolase Pden_2044 31 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 119384827 Common - DSBA oxidoreductase Pden_2095 76 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 119385205 Common - putative transcriptional regulator, Crp/Fnr family Pden_2478 147 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 119384195 Common - major facilitator superfamily MFS_1 Pden_1455 42 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 119383750 Nonpathogen - hypothetical protein Pden_0999 2 None None None 119383113 Common - phage Terminase Pden_0359 40 COG4626 COG4626, Phage terminase-like protein, large subunit General function prediction only 119383069 Common - oxidoreductase domain protein Pden_0315 200 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 119384899 Common - (Glutamate--ammonia-ligase) adenylyltransferase Pden_2167 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 119382896 Common - hypothetical protein Pden_0139 26 COG3843 VirD2, Type IV secretory pathway, VirD2 components (relaxase) Intracellular trafficking and secretion 119382878 Nonpathogen - hypothetical protein Pden_0121 1 None None None 119384576 Common - ABC transporter related Pden_1839 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 119382813 Common - N-formylglutamate amidohydrolase Pden_0056 57 COG3741 HutG, N-formylglutamate amidohydrolase Amino acid transport and metabolism 119382876 Common - hypothetical protein Pden_0119 4 None None None 119382834 Common - transposase Pden_0077 75 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 119382881 Nonpathogen - hypothetical protein Pden_0124 1 None None None 119383533 Common - adenylate kinase Pden_0781 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 119384931 Common - hypothetical protein Pden_2199 34 COG5465 COG5465, Uncharacterized conserved protein Function unknown 119383954 Common - urease, beta subunit Pden_1209 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 119383475 Common - protein of unknown function DUF21 Pden_0723 218 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 119383657 Common - multiple antibiotic resistance (MarC)-related proteins Pden_0906 145 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 119384459 Common - transcriptional regulator, GntR family Pden_1722 141 COG1802 GntR, Transcriptional regulators Transcription 119384989 Common - succinic semialdehyde dehydrogenase Pden_2257 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 119382826 Common - hypothetical protein Pden_0069 5 None None None 119383708 Common - polyhydroxyalkanoate depolymerase, intracellular Pden_0957 44 COG4553 DepA, Poly-beta-hydroxyalkanoate depolymerase Lipid metabolism 119383791 Common - short chain dehydrogenase Pden_1040 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119385434 Common - glucose sorbosone dehydrogenase Pden_2710 120 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 119384143 Common - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase Pden_1402 117 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 119383538 Common - response regulator receiver protein Pden_0786 10 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 119384461 Common - hypothetical protein Pden_1724 5 None None None 119384977 Common - hypothetical protein Pden_2245 27 COG3743 COG3743, Uncharacterized conserved protein Function unknown 119383360 Common - extracellular solute-binding protein, family 5 Pden_0608 197 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 119384154 Common - heme exporter protein CcmA Pden_1413 249 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 119383340 Common - phospho-N-acetylmuramoyl-pentapeptide-transferase Pden_0588 216 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 119384719 Common - acetyl-CoA carboxylase, carboxyl transferase, beta subunit Pden_1987 217 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 119383290 Common glyQ glycyl-tRNA synthetase subunit alpha Pden_0538 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 119383897 Common - polar amino acid ABC transporter, inner membrane subunit Pden_1149 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 119384487 Common - transferase hexapeptide repeat containing protein Pden_1750 80 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 119382782 Common - hypothetical protein Pden_0025 10 None None None 119383881 Nonpathogen - hypothetical protein Pden_1133 3 None None None 119384447 Common - Betaine-aldehyde dehydrogenase Pden_1710 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 119384126 Common - 5-formyltetrahydrofolate cyclo-ligase Pden_1385 145 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 119385351 Common - transcriptional regulator, TetR family Pden_2624 110 COG1309 AcrR, Transcriptional regulator Transcription 119382848 Nonpathogen - hypothetical protein Pden_0091 2 None None None 119383234 Common - SpoVT/AbrB domain protein Pden_0482 14 COG4456 VagC, Virulence-associated protein and related proteins Function unknown 119384019 Common - protein of unknown function DUF6, transmembrane Pden_1274 103 COG2510 COG2510, Predicted membrane protein Function unknown 119385030 Common - 3-deoxy-manno-octulosonate cytidylyltransferase Pden_2299 138 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 119383859 Common - NCS1 nucleoside transporter family Pden_1111 72 COG1953 FUI1, Cytosine/uracil/thiamine/allantoin permeases Nucleotide transport and metabolism / Coenzyme metabolism 119384024 Common - phage integrase family protein Pden_1279 214 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 119382846 Common - hypothetical protein Pden_0089 14 COG4310 COG4310, Uncharacterized protein conserved in bacteria with an aminopeptidase-like domain General function prediction only 119384944 Common - protein of unknown function DUF185 Pden_2212 93 COG1565 COG1565, Uncharacterized conserved protein Function unknown 119384981 Common - NADH dehydrogenase subunit B Pden_2249 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 119382871 Nonpathogen - SH3, type 3 domain protein Pden_0114 2 COG4991 COG4991, Uncharacterized protein with a bacterial SH3 domain homologue Function unknown 119384955 Common - cytidine deaminase Pden_2223 112 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 119383895 Common - extracellular solute-binding protein, family 3 Pden_1147 164 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 119385540 Common - putative ribonuclease BN Pden_2816 37 COG1295 Rbn, Predicted membrane protein Function unknown 119385312 Common - competence protein F Pden_2585 50 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 119383393 Common - hypothetical protein Pden_0641 44 COG3247 HdeD, Uncharacterized conserved protein Function unknown 119384904 Common - peptidase M48, Ste24p Pden_2172 71 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 119385260 Common - precorrin-3B synthase Pden_2533 35 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 119385218 Common - putative transcriptional regulator, AsnC family Pden_2491 51 COG1522 Lrp, Transcriptional regulators Transcription 119385035 Common radC DNA repair protein RadC Pden_2304 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 119385134 Common - D-alanine--D-alanine ligase Pden_2406 210 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 119383727 Nonpathogen - hypothetical protein Pden_0976 1 None None None 119384062 Common - Formate--tetrahydrofolate ligase Pden_1317 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 119384302 Common - hypothetical protein Pden_1562 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 119385519 Common - putative helicase/exonuclease Pden_2795 51 COG3893 COG3893, Inactivated superfamily I helicase DNA replication, recombination, and repair 119383759 Common - phosphate acetyltransferase Pden_1008 154 COG0280 Pta, Phosphotransacetylase Energy production and conversion 119383367 Common - putative bacterioferritin-associated ferredoxin Pden_0615 7 None None None 119383379 Nonpathogen - hypothetical protein Pden_0627 6 None None None 119385010 Nonpathogen - hypothetical protein Pden_2278 1 None None None 119385300 Common - Hsp33 protein Pden_2573 131 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 119384321 Common - hypothetical protein Pden_1581 28 COG4645 COG4645, Uncharacterized protein conserved in bacteria Function unknown 119382965 Common - putative transcriptional regulator, MerR family Pden_0211 136 COG0789 SoxR, Predicted transcriptional regulators Transcription 119384711 Common - methionine aminopeptidase, type I Pden_1979 247 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 119382986 Common - transcriptional regulator, TetR family Pden_0232 75 COG1309 AcrR, Transcriptional regulator Transcription 119384272 Common - hypothetical protein Pden_1532 44 None None None 119385345 Common - glycerol kinase Pden_2618 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 119384182 Common - hypothetical protein Pden_1441 68 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 119383509 Nonpathogen - hypothetical protein Pden_0757 1 None None None 119384226 Common - TonB-dependent receptor Pden_1486 89 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 119383202 Common - hypothetical protein Pden_0448 10 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 119384365 Common - hypothetical protein Pden_1627 54 COG3391 COG3391, Uncharacterized conserved protein Function unknown 119383085 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pden_0331 46 COG0400 COG0400, Predicted esterase General function prediction only 119384996 Common - Glutathione S-transferase, N-terminal domain Pden_2264 100 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 119385494 Common - major facilitator superfamily MFS_1 Pden_2770 122 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 119383674 Nonpathogen - hypothetical protein Pden_0923 1 None None None 119383613 Common - aspartate kinase Pden_0862 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 119383769 Common - creatinase Pden_1018 109 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 119385392 Common - molybdenum ABC transporter, periplasmic molybdate-binding protein Pden_2665 153 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 119385315 Nonpathogen - transcriptional regulator, MarR family Pden_2588 6 COG1846 MarR, Transcriptional regulators Transcription 119384571 Common - Glutathione S-transferase, C-terminal domain Pden_1834 85 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 119383945 Common - hypothetical protein Pden_1200 7 None None None 119383650 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Pden_0899 99 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 119384456 Common - malonyl-CoA synthase Pden_1719 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 119383370 Common - Nucleotidyl transferase Pden_0618 231 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 119385269 Common - precorrin 6A synthase Pden_2542 24 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 119383314 Common - protein of unknown function DUF81 Pden_0562 40 COG0730 COG0730, Predicted permeases General function prediction only 119384278 Common - hypothetical protein Pden_1538 4 None None None 119385028 Common - Nucleotidyl transferase Pden_2297 233 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 119383511 Common rplC 50S ribosomal protein L3 Pden_0759 220 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 119385006 Common rpmI 50S ribosomal protein L35 Pden_2274 113 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 119383617 Common - periplasmic binding protein Pden_0866 80 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 119383602 Common - Rhodanese domain protein Pden_0850 107 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 119383440 Common - hypothetical protein Pden_0688 14 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 119383469 Common - polar amino acid ABC transporter, inner membrane subunit Pden_0717 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 119384309 Common - extracellular solute-binding protein, family 5 Pden_1569 197 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 119383012 Nonpathogen - hypothetical protein Pden_0258 1 None None None 119383677 Common - protein of unknown function DUF305 Pden_0926 53 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 119384497 Common - ketol-acid reductoisomerase Pden_1760 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 119384797 Common - putative cold-shock DNA-binding domain protein Pden_2065 176 COG1278 CspC, Cold shock proteins Transcription 119385435 Common - hypothetical protein Pden_2711 17 None None None 119383607 Common - xanthine-guanine phosphoribosyltransferase Pden_0855 52 COG2236 COG2236, Predicted phosphoribosyltransferases General function prediction only 119383768 Common - transposase IS116/IS110/IS902 family protein Pden_1017 91 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 119382937 Common - glucose-methanol-choline oxidoreductase Pden_0181 92 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 119383243 Common - undecaprenyl pyrophosphate phosphatase Pden_0491 199 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 119385534 Nonpathogen - glycosyl transferase, family 8 Pden_2810 5 COG5597 COG5597, Alpha-N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 119384790 Common - hypothetical protein Pden_2058 11 None None None 119383695 Common - transcriptional regulator, TetR family Pden_0944 12 None None None 119382805 Common - AMP-dependent synthetase and ligase Pden_0048 212 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 119385532 Nonpathogen - hypothetical protein Pden_2808 1 None None None 119383974 Common - hypothetical protein Pden_1229 4 None None None 119385511 Common - Smr protein/MutS2 Pden_2787 68 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 119383193 Nonpathogen - hypothetical protein Pden_0439 1 None None None 119383902 Common - hypothetical protein Pden_1154 6 None None None 119382944 Common - regulatory proteins, IclR Pden_0188 81 COG1414 IclR, Transcriptional regulator Transcription 119383692 Common - Malate/L-lactate dehydrogenase Pden_0941 67 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 119383553 Common - binding-protein-dependent transport systems inner membrane component Pden_0801 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 119383839 Common - histidinol dehydrogenase Pden_1091 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 119384782 Nonpathogen - hypothetical protein Pden_2050 1 None None None 119385021 Common - domain of unknown function DUF1730 Pden_2290 133 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 119383686 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pden_0935 119 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 119385395 Common - hypothetical protein Pden_2668 38 COG4764 COG4764, Uncharacterized protein conserved in bacteria Function unknown 119383551 Common - Citrate (pro-3S)-lyase Pden_0799 117 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 119384225 Common - helix-turn-helix- domain containing protein, AraC type Pden_1485 28 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 119384921 Common - cobalt chelatase, pCobS small subunit Pden_2189 64 COG0714 COG0714, MoxR-like ATPases General function prediction only 119383568 Common - sodium-dependent inorganic phosphate (Pi) transporter Pden_0816 66 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 119384059 Common mdoG glucan biosynthesis protein G Pden_1314 50 COG3131 MdoG, Periplasmic glucans biosynthesis protein Inorganic ion transport and metabolism 119383268 Nonpathogen - Sarcosine oxidase, gamma subunit Pden_0516 4 COG4583 COG4583, Sarcosine oxidase gamma subunit Amino acid transport and metabolism 119385254 Common - cob(II)yrinic acid a,c-diamide reductase Pden_2527 64 COG0778 NfnB, Nitroreductase Energy production and conversion 119383219 Common - putative spermidine/putrescine-binding protein Pden_0467 36 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 119385119 Nonpathogen - hypothetical protein Pden_2390 4 None None None 119383274 Common - ErfK/YbiS/YcfS/YnhG family protein Pden_0522 88 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 119383661 Common - protein of unknown function DUF815 Pden_0910 89 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 119383561 Common - Lytic transglycosylase, catalytic Pden_0809 140 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 119383582 Common - binding-protein-dependent transport systems inner membrane component Pden_0830 154 COG4132 COG4132, ABC-type uncharacterized transport system, permease component General function prediction only 119383053 Common - transport system permease protein Pden_0299 173 COG4606 CeuB, ABC-type enterochelin transport system, permease component Inorganic ion transport and metabolism 119384414 Common - Xylose isomerase domain protein TIM barrel Pden_1677 14 COG4130 COG4130, Predicted sugar epimerase Carbohydrate transport and metabolism 119384657 Common hisG ATP phosphoribosyltransferase catalytic subunit Pden_1923 145 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 119384207 Common - Lysine exporter protein (LYSE/YGGA) Pden_1467 107 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 119384257 Common - transcriptional regulator, XRE family Pden_1517 11 None None None 119384698 Nonpathogen - hypothetical protein Pden_1966 1 None None None 119385365 Nonpathogen - hypothetical protein Pden_2638 2 None None None 119383489 Common - glutathione-dependent formaldehyde-activating, GFA Pden_0737 32 COG3791 COG3791, Uncharacterized conserved protein Function unknown 119385142 Nonpathogen - hypothetical protein Pden_2414 1 None None None 119383032 Common - major facilitator superfamily MFS_1 Pden_0278 147 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 119383463 Common - histidine ammonia-lyase Pden_0711 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 119384251 Common - hypothetical protein Pden_1511 23 None None None 119385502 Common - putative PAS/PAC sensor protein Pden_2778 32 None None None 119384023 Common - protein of unknown function DUF21 Pden_1278 218 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 119384098 Nonpathogen - hypothetical protein Pden_1357 1 None None None 119384441 Common - Radical SAM domain protein Pden_1704 102 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 119383809 Common - glyceraldehyde-3-phosphate dehydrogenase, type I Pden_1060 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 119384375 Nonpathogen - hypothetical protein Pden_1637 1 None None None 119383010 Nonpathogen - hypothetical protein Pden_0256 1 None None None 119384538 Common - heat shock protein DnaJ domain protein Pden_1801 57 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 119383381 Nonpathogen - hypothetical protein Pden_0629 1 None None None 119385136 Nonpathogen - hypothetical protein Pden_2408 1 None None None 119383206 Nonpathogen - hypothetical protein Pden_0453 1 None None None 119384672 Nonpathogen - hypothetical protein Pden_1939 11 COG5488 COG5488, Integral membrane protein Function unknown 119384428 Common - transcriptional regulator, LysR family Pden_1691 169 COG0583 LysR, Transcriptional regulator Transcription 119384758 Common - acetyl-CoA acetyltransferase Pden_2026 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 119385303 Common - ABC transporter related Pden_2576 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 119383680 Common - exodeoxyribonuclease III Xth Pden_0929 196 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 119382832 Common - hypothetical protein Pden_0075 17 COG2388 COG2388, Predicted acetyltransferase General function prediction only 119385288 Common - protein of unknown function DUF6, transmembrane Pden_2561 104 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 119384546 Common - prephenate dehydratase Pden_1809 212 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 119383746 Common - hypothetical protein Pden_0995 4 None None None 119383279 Common - ABC transporter related Pden_0527 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 119383783 Common - periplasmic binding protein/LacI transcriptional regulator Pden_1032 57 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 119384091 Common - methylcitrate synthase Pden_1347 192 COG0372 GltA, Citrate synthase Energy production and conversion 119383395 Common - dienelactone hydrolase Pden_0643 20 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 119384314 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Pden_1574 16 COG0748 HugZ, Putative heme iron utilization protein Inorganic ion transport and metabolism 119385465 Nonpathogen - hypothetical protein Pden_2741 1 None None None 119382994 Common - transcriptional regulator, GntR family Pden_0240 92 COG1802 GntR, Transcriptional regulators Transcription 119384912 Common - GCN5-related N-acetyltransferase Pden_2180 82 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 119385536 Common - transcriptional regulator, BadM/Rrf2 family Pden_2812 157 COG1959 COG1959, Predicted transcriptional regulator Transcription 119385509 Common - FxsA cytoplasmic membrane protein Pden_2785 60 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 119384044 Common - prolyl-tRNA synthetase Pden_1299 249 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 119385175 Common - protein of unknown function DUF1305 Pden_2448 31 COG3520 COG3520, Uncharacterized protein conserved in bacteria Function unknown 119382769 Common - Endoribonuclease L-PSP Pden_0012 75 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 119383283 Common - nitrogen-fixing NifU domain protein Pden_0531 103 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 119383799 Common - binding-protein-dependent transport systems inner membrane component Pden_1048 158 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 119384034 Common - putative monovalent cation/H+ antiporter subunit A Pden_1289 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 119382890 Common - hypothetical protein Pden_0133 23 None None None 119383106 Common - hypothetical protein Pden_0352 25 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 119384526 Nonpathogen - surface presentation of antigens (SPOA) protein Pden_1789 6 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 119383048 Common - Hemolysin-type calcium-binding region Pden_0294 90 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 119383731 Nonpathogen - hypothetical protein Pden_0980 1 None None None 119385124 Common - putative transcriptional regulators, CopG/Arc/MetJ family Pden_2396 28 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 119384169 Common - helix-turn-helix- domain containing protein, AraC type Pden_1428 102 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 119382777 Common - Pyrrolo-quinoline quinone Pden_0020 61 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 119383151 Common - histone deacetylase superfamily Pden_0397 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 119384659 Common hisS histidyl-tRNA synthetase Pden_1925 249 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 119383964 Nonpathogen - hypothetical protein Pden_1219 1 None None None 119383627 Common - diguanylate phosphodiesterase Pden_0876 129 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 119384892 Common - periplasmic binding protein/LacI transcriptional regulator Pden_2160 95 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 119384618 Common hisB imidazoleglycerol-phosphate dehydratase Pden_1883 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 119382959 Nonpathogen - hypothetical protein Pden_0205 1 None None None 119383017 Common - DNA-cytosine methyltransferase Pden_0263 69 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 119384284 Common - domain of unknown function DUF1738 Pden_1544 48 COG4227 COG4227, Antirestriction protein DNA replication, recombination, and repair 119385045 Common - hypothetical protein Pden_2314 21 COG3218 COG3218, ABC-type uncharacterized transport system, auxiliary component General function prediction only 119385087 Common - ABC transporter related Pden_2357 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 119383712 Common - phage integrase family protein Pden_0961 14 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 119385184 Nonpathogen - hypothetical protein Pden_2457 4 None None None 119382952 Common - short-chain dehydrogenase/reductase SDR Pden_0196 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119383229 Common - transcriptional regulator, XRE family Pden_0477 105 COG1476 COG1476, Predicted transcriptional regulators Transcription 119383652 Common - permease YjgP/YjgQ family protein Pden_0901 29 COG0795 COG0795, Predicted permeases General function prediction only 119385164 Common - hypothetical protein Pden_2437 7 None None None 119383797 Common - regulatory protein, LacI Pden_1046 126 COG1609 PurR, Transcriptional regulators Transcription 119384050 Common - Antibiotic biosynthesis monooxygenase Pden_1305 7 COG1359 COG1359, Uncharacterized conserved protein Function unknown 119384004 Common - periplasmic solute binding protein Pden_1259 166 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 119383006 Common - transposase (class I) Pden_0252 18 None None None 119384626 Common - queuine tRNA-ribosyltransferase Pden_1891 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 119385149 Nonpathogen - transcriptional regulator, XRE family Pden_2421 1 COG1396 HipB, Predicted transcriptional regulators Transcription 119383841 Common - putative transcriptional regulator, XRE family Pden_1093 11 COG1396 HipB, Predicted transcriptional regulators Transcription 119383810 Common - protein of unknown function DUF224, cysteine-rich region domain protein Pden_1061 90 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 119383521 Common rplN 50S ribosomal protein L14 Pden_0769 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 119382851 Common - transposase IS116/IS110/IS902 Pden_0094 20 None None None 119383800 Common - binding-protein-dependent transport systems inner membrane component Pden_1049 155 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 119384118 Common - Redoxin domain protein Pden_1377 83 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 119383529 Common rpmD 50S ribosomal protein L30 Pden_0777 98 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 119385178 Common - protein of unknown function DUF876 Pden_2451 48 COG3522 COG3522, Uncharacterized protein conserved in bacteria Function unknown 119385082 Common - histidine kinase Pden_2352 217 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 119385143 Common - transcriptional regulator, XRE family Pden_2415 35 COG1396 HipB, Predicted transcriptional regulators Transcription 119383305 Nonpathogen - hypothetical protein Pden_0553 1 None None None 119384739 Common - hypothetical protein Pden_2007 4 None None None 119383957 Common - Urease accessory protein UreD Pden_1212 78 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 119384641 Common - Uncharacterized protein related to arylsulfate sulfotransferase Pden_1906 29 COG4321 COG4321, Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis General function prediction only 119384065 Common - hypothetical protein Pden_1320 15 None None None 119383064 Common - two component transcriptional regulator, winged helix family Pden_0310 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 119385294 Common - periplasmic binding protein Pden_2567 91 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 119384333 Common - Ppx/GppA phosphatase Pden_1593 180 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 119384753 Nonpathogen - hypothetical protein Pden_2021 1 None None None 119384975 Common - NADH-quinone oxidoreductase, F subunit Pden_2243 166 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 119384463 Common - hypothetical protein Pden_1726 4 None None None 119385477 Common - 5-carboxymethyl-2-hydroxymuconate delta-isomerase Pden_2753 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 119385073 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Pden_2342 198 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 119383402 Common - MATE efflux family protein Pden_0650 166 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 119385103 Nonpathogen - hypothetical protein Pden_2373 1 None None None 119384407 Common - binding-protein-dependent transport systems inner membrane component Pden_1670 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 119384494 Common - Serine-type D-Ala-D-Ala carboxypeptidase Pden_1757 153 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 119385270 Nonpathogen - hypothetical protein Pden_2543 2 COG5469 COG5469, Predicted metal-binding protein Function unknown 119383857 Common - rhodanese-like Pden_1109 18 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 119385336 Common - 3'-5' exonuclease Pden_2609 102 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 119384804 Nonpathogen - hypothetical protein Pden_2072 1 None None None 119383594 Common - Undecaprenyl-phosphate galactose phosphotransferase Pden_0842 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 119385525 Common truB tRNA pseudouridine synthase B Pden_2801 244 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 119384384 Common - TRAP dicarboxylate transporter, DctP subunit Pden_1647 100 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 119383210 Common - hypothetical protein Pden_0457 5 None None None 119384295 Common - 3,4-dihydroxy-2-butanone 4-phosphate synthase Pden_1555 229 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 119383543 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Pden_0791 114 COG0546 Gph, Predicted phosphatases General function prediction only 119383167 Common - DEAD/H associated domain protein Pden_0413 139 COG1201 Lhr, Lhr-like helicases General function prediction only 119384561 Common - hypothetical protein Pden_1824 9 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 119382918 Common - efflux transporter, RND family, MFP subunit Pden_0161 175 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 119384151 Common - periplasmic protein thiol--disulphide oxidoreductase DsbE Pden_1410 141 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 119382839 Nonpathogen - hypothetical protein Pden_0082 1 None None None 119384515 Common - drug resistance transporter, Bcr/CflA subfamily Pden_1778 157 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 119383808 Nonpathogen - hypothetical protein Pden_1059 1 None None None 119384265 Common - hypothetical protein Pden_1525 45 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 119384106 Common - protein of unknown function DUF955 Pden_1365 45 COG3800 COG3800, Predicted transcriptional regulator General function prediction only 119383495 Common rplK 50S ribosomal protein L11 Pden_0743 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 119385110 Common - metallophosphoesterase Pden_2380 45 COG1409 Icc, Predicted phosphohydrolases General function prediction only 119385155 Nonpathogen - hypothetical protein Pden_2428 1 None None None 119383871 Common - transcriptional regulator, Fis family Pden_1123 202 COG4566 TtrR, Response regulator Signal transduction mechanisms 119384778 Common - TonB-dependent receptor Pden_2046 126 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 119384889 Common - short-chain dehydrogenase/reductase SDR Pden_2157 234 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 119385443 Common - Heparinase II/III family protein Pden_2719 33 COG5360 COG5360, Uncharacterized protein conserved in bacteria Function unknown 119385329 Common - branched-chain amino acid aminotransferase Pden_2602 217 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 119384274 Common - filamentation induced by cAMP protein Fic Pden_1534 23 COG3177 COG3177, Uncharacterized conserved protein Function unknown 119384839 Common - Extensin family protein Pden_2107 36 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 119384531 Nonpathogen - hypothetical protein Pden_1794 1 None None None 119383649 Common pdxA 4-hydroxythreonine-4-phosphate dehydrogenase Pden_0898 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 119384073 Common - extracellular solute-binding protein, family 5 Pden_1328 198 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 119382793 Common - NlpA lipoprotein Pden_0036 105 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 119383037 Common - amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Pden_0283 175 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 119384138 Common - Glutamate--ammonia ligase Pden_1397 225 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 119385057 Common - transcriptional regulator, HxlR family Pden_2326 86 COG1733 COG1733, Predicted transcriptional regulators Transcription 119385245 Common - iojap-like protein Pden_2518 193 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 119384554 Common - N-acetylmuramoyl-L-alanine amidase Pden_1817 180 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 119385389 Common - hypothetical protein Pden_2662 79 COG1738 COG1738, Uncharacterized conserved protein Function unknown 119385442 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase Pden_2718 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 119383142 Nonpathogen - hypothetical protein Pden_0388 1 None None None 119383358 Common - binding-protein-dependent transport systems inner membrane component Pden_0606 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 119383868 Common - luciferase family protein Pden_1120 40 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 119382784 Common - 40-residue YVTN family beta-propeller repeat protein Pden_0027 84 COG3391 COG3391, Uncharacterized conserved protein Function unknown 119384707 Nonpathogen - hypothetical protein Pden_1975 1 None None None 119383428 Common - protein of unknown function DUF81 Pden_0676 26 None None None 119385197 Common - binding-protein-dependent transport systems inner membrane component Pden_2470 175 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 119384170 Common - Lysine exporter protein (LYSE/YGGA) Pden_1429 83 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 119383026 Common - phage conserved hypothetical protein BR0599 Pden_0272 29 COG5449 COG5449, Uncharacterized conserved protein Function unknown 119385239 Common - YbaK/prolyl-tRNA synthetase associated region Pden_2512 60 COG2606 EbsC, Uncharacterized conserved protein Function unknown 119383182 Nonpathogen - GCN5-related N-acetyltransferase Pden_0428 4 COG0456 RimI, Acetyltransferases General function prediction only 119383131 Nonpathogen - hypothetical protein Pden_0377 1 None None None 119384354 Common - thioesterase superfamily protein Pden_1614 61 COG0824 FcbC, Predicted thioesterase General function prediction only 119385097 Common - Alcohol dehydrogenase GroES domain protein Pden_2367 209 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 119383136 Nonpathogen - hypothetical protein Pden_0382 2 None None None 119383073 Common - hypothetical protein Pden_0319 23 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 119385411 Common - hypothetical protein Pden_2684 14 None None None 119385405 Common - protein of unknown function DUF490 Pden_2678 98 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 119383150 Common - MiaB-like tRNA modifying enzyme Pden_0396 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 119384690 Common - hypothetical protein Pden_1958 31 COG5328 COG5328, Uncharacterized protein conserved in bacteria Function unknown 119384505 Common acpP acyl carrier protein Pden_1768 209 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 119383128 Nonpathogen - hypothetical protein Pden_0374 1 None None None 119384301 Common - riboflavin biosynthesis protein RibD Pden_1561 221 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 119383626 Common - PP-loop domain protein Pden_0875 161 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 119384005 Common - ferric uptake regulator, Fur family Pden_1260 165 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 119383176 Common - pyridoxal phosphate biosynthetic protein PdxJ Pden_0422 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 119384366 Common - TonB-dependent receptor, plug Pden_1628 131 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 119384784 Nonpathogen - hypothetical protein Pden_2052 1 None None None 119383199 Common - hypothetical protein Pden_0445 23 None None None 119385374 Nonpathogen - hypothetical protein Pden_2647 3 None None None 119385207 Common - cytochrome c oxidase, subunit III Pden_2480 33 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 119383329 Nonpathogen - hypothetical protein Pden_0577 1 None None None 119383631 Common - acetylglutamate kinase Pden_0880 213 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 119385475 Common - Aldose 1-epimerase Pden_2751 95 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 119384500 Common - ABC transporter related Pden_1763 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 119385237 Common - lytic murein transglycosylase Pden_2510 104 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 119384645 Common - hypothetical protein Pden_1911 12 None None None 119383109 Nonpathogen - hypothetical protein Pden_0355 2 None None None 119383900 Common - ABC transporter related Pden_1152 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 119383604 Common - nicotinate phosphoribosyltransferase Pden_0852 77 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 119383081 Common - transcriptional regulator, LysR family Pden_0327 130 COG0583 LysR, Transcriptional regulator Transcription 119383090 Nonpathogen - hypothetical protein Pden_0336 1 None None None 119384340 Common - transcriptional regulator, LysR family Pden_1600 189 COG0583 LysR, Transcriptional regulator Transcription 119383536 Common - DNA-directed RNA polymerase subunit alpha Pden_0784 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 119384932 Common - aminotransferase, class I and II Pden_2200 190 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 119384022 Common - uracil-xanthine permease Pden_1277 127 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 119384275 Common - hypothetical protein Pden_1535 7 None None None 119382891 Common - transposase IS116/IS110/IS902 family protein Pden_0134 97 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 119383231 Common - short-chain dehydrogenase/reductase SDR Pden_0479 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119382803 Common - two component transcriptional regulator, winged helix family Pden_0046 213 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 119383619 Nonpathogen - hypothetical protein Pden_0868 1 None None None 119384814 Nonpathogen - hypothetical protein Pden_2082 5 None None None 119385346 Common - transcriptional regulator, DeoR family Pden_2619 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 119382910 Common - AAA ATPase Pden_0153 60 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 119384774 Common - ABC-2 type transporter Pden_2042 159 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 119385485 Common - type I secretion target repeat protein Pden_2761 25 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 119382905 Common - Conjugal transfer protein TrbG/VirB9/CagX Pden_0148 52 COG3504 VirB9, Type IV secretory pathway, VirB9 components Intracellular trafficking and secretion 119384746 Common - ABC transporter related Pden_2014 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 119385492 Common - HI0933 family protein Pden_2768 114 COG2081 COG2081, Predicted flavoproteins General function prediction only 119383980 Common - ABC transporter related Pden_1235 246 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 119384495 Common - putative transcriptional regulator, AsnC family Pden_1758 152 COG1522 Lrp, Transcriptional regulators Transcription 119385217 Common - cytochrome d1, heme region Pden_2490 37 COG3391 COG3391, Uncharacterized conserved protein Function unknown 119385513 Common - hypothetical protein Pden_2789 12 None None None 119383038 Common - Asp/Glu racemase Pden_0284 34 COG3473 COG3473, Maleate cis-trans isomerase Secondary metabolites biosynthesis, transport, and catabolism 119382821 Common - Ferric reductase domain protein transmembrane component, N-terminal domain Pden_0064 68 COG2717 COG2717, Predicted membrane protein Function unknown 119385335 Common - KpsF/GutQ family protein Pden_2608 149 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 119383993 Common - extracellular solute-binding protein, family 5 Pden_1248 197 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 119383159 Common - histone family protein DNA-binding protein Pden_0405 40 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 119384675 Common - protein of unknown function DUF1058 Pden_1942 43 COG3807 COG3807, Uncharacterized protein conserved in bacteria Function unknown 119385546 Common - two-component response regulator Pden_2822 123 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 119383673 Common - peptide chain release factor 3 Pden_0922 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 119384067 Nonpathogen - hypothetical protein Pden_1322 3 None None None 119383246 Common - NUDIX hydrolase Pden_0494 21 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 119384116 Nonpathogen - hypothetical protein Pden_1375 1 None None None 119383123 Common - hypothetical protein Pden_0369 4 None None None 119383907 Common - HPP family protein+B94 Pden_1160 66 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 119384385 Common - putative transcriptional regulator, GntR family Pden_1648 166 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 119384829 Common - HhH-GPD family protein Pden_2097 212 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 119384738 Common - hypothetical protein Pden_2006 8 COG4421 COG4421, Capsular polysaccharide biosynthesis protein Carbohydrate transport and metabolism 119382963 Common - transcriptional regulator, LysR family Pden_0209 138 COG0583 LysR, Transcriptional regulator Transcription 119385310 Common hemH ferrochelatase Pden_2583 163 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 119385427 Common - transposase, IS4 family protein Pden_2703 46 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 119382960 Common - short-chain dehydrogenase/reductase SDR Pden_0206 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119383507 Common - elongation factor G Pden_0755 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 119383531 Common rplO 50S ribosomal protein L15 Pden_0779 216 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 119383784 Common - ABC transporter related Pden_1033 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 119384058 Nonpathogen - hypothetical protein Pden_1313 1 None None None 119384167 Nonpathogen - major facilitator superfamily MFS_1 Pden_1426 1 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 119384471 Common - protein of unknown function DUF451 Pden_1734 29 COG2822 COG2822, Predicted periplasmic lipoprotein involved in iron transport Inorganic ion transport and metabolism 119385122 Common - hypothetical protein Pden_2394 13 None None None 119383878 Common - hypothetical protein Pden_1130 12 None None None 119384450 Common - inner-membrane translocator Pden_1713 81 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 119384322 Common - glucosyltransferase MdoH Pden_1582 60 COG2943 MdoH, Membrane glycosyltransferase Cell envelope biogenesis, outer membrane 119385543 Common - signal transduction histidine kinase Pden_2819 87 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 119384329 Nonpathogen - hypothetical protein Pden_1589 1 None None None 119384661 Nonpathogen - hypothetical protein Pden_1927 6 None None None 119382969 Common - arsenate reductase Pden_0215 108 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 119385277 Common - electron transfer flavoprotein beta-subunit Pden_2550 152 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 119383811 Common - flavin reductase domain protein, FMN-binding Pden_1062 55 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 119384967 Common - NADH dehydrogenase subunit J Pden_2235 99 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 119385420 Common - Paraquat-inducible protein A Pden_2693 55 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 119383236 Common - RelE-like cytotoxic translational repressor of toxin-antitoxin stability system Pden_0484 27 None None None 119384717 Common - transcriptional coactivator/pterin dehydratase Pden_1985 38 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 119385424 Common flgK flagellar hook-associated protein FlgK Pden_2697 115 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 119384582 Common - cytochrome c oxidase, cbb3-type, subunit III Pden_1845 82 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 119384484 Common - ABC transporter related Pden_1747 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 119383400 Common - aminotransferase, class I and II Pden_0648 239 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 119382815 Common - NUDIX hydrolase Pden_0058 9 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 119384987 Nonpathogen - hypothetical protein Pden_2255 4 None None None 119383294 Common - cell wall hydrolase, SleB Pden_0542 48 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 119384622 Common - imidazole glycerol phosphate synthase subunit HisF Pden_1887 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 119384939 Common - binfunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein Pden_2207 59 COG2046 MET3, ATP sulfurylase (sulfate adenylyltransferase) Inorganic ion transport and metabolism 119384560 Common - hypothetical protein Pden_1823 162 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 119385162 Nonpathogen - hypothetical protein Pden_2435 3 None None None 119383753 Nonpathogen - hypothetical protein Pden_1002 1 None None None 119385396 Common - outer membrane lipoprotein carrier protein LolA Pden_2669 36 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 119384213 Common - MaoC domain protein dehydratase Pden_1473 73 COG2030 MaoC, Acyl dehydratase Lipid metabolism 119385225 Common - primosome assembly protein PriA Pden_2498 212 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 119385054 Common - putative methyltransferase Pden_2323 204 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 119384485 Common - MltA-interacting MipA family protein Pden_1748 30 COG3713 OmpV, Outer membrane protein V Cell envelope biogenesis, outer membrane 119383977 Common - HI0933 family protein Pden_1232 137 COG2081 COG2081, Predicted flavoproteins General function prediction only 119382870 Common - TIR protein Pden_0113 26 None None None 119384084 Common - hypothetical protein Pden_1339 16 None None None 119385132 Common - hypothetical protein Pden_2404 45 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 119383771 Common - transcriptional regulator, LysR family Pden_1020 162 COG0583 LysR, Transcriptional regulator Transcription 119384101 Common - ABC transporter related Pden_1360 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 119383077 Common - Carbamoyl-phosphate synthase L chain, ATP-binding Pden_0323 234 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 119385448 Nonpathogen - hypothetical protein Pden_2724 2 None None None 119384953 Common - phosphopentomutase Pden_2221 70 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 119383829 Common - beta-lactamase domain protein Pden_1080 22 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 119383824 Common - ABC transporter related Pden_1075 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 119383566 Common - D-3-phosphoglycerate dehydrogenase Pden_0814 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 119383893 Common - intracellular protease, PfpI family Pden_1145 143 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 119385063 Common - cobalamin (vitamin B12) biosynthesis CbiX protein Pden_2332 11 COG2138 COG2138, Uncharacterized conserved protein Function unknown 119383346 Common - Fmu (Sun) domain protein Pden_0594 196 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 119383338 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase Pden_0586 209 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 119385139 Common - outer membrane efflux protein Pden_2411 72 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 119383365 Common - major facilitator superfamily MFS_1 Pden_0613 74 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 119382860 Common - protein of unknown function DUF132 Pden_0103 15 COG1569 COG1569, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 119384231 Common - transcriptional regulator, TetR family Pden_1491 6 None None None 119385031 Common - 3'(2'),5'-bisphosphate nucleotidase Pden_2300 185 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 119384376 Common - hypothetical protein Pden_1638 17 None None None 119384832 Common - hypothetical protein Pden_2100 13 None None None 119383044 Common - hypothetical protein Pden_0290 235 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 119383399 Common - peptide deformylase Pden_0647 215 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 119382831 Common - adenylate cyclase Pden_0074 46 COG2954 COG2954, Uncharacterized protein conserved in bacteria Function unknown 119384971 Common - NADH dehydrogenase subunit H Pden_2239 192 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 119385000 Common - rpsU-divergently transcribed protein Pden_2268 26 COG5590 COG5590, Uncharacterized conserved protein Function unknown 119384121 Common - protein of unknown function DUF853, NPT hydrolase putative Pden_1380 77 COG0433 COG0433, Predicted ATPase General function prediction only 119384478 Nonpathogen - hypothetical protein Pden_1741 1 None None None 119383574 Common - peptidase domain protein Pden_0822 93 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 119383944 Common - amidohydrolase Pden_1199 165 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 119383548 Common - ABC transporter related Pden_0796 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 119383285 Common - sugar transferase Pden_0533 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 119384879 Common - beta-lactamase domain protein Pden_2147 60 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 119383864 Common - protein of unknown function UPF0052 and CofD Pden_1116 39 COG0391 COG0391, Uncharacterized conserved protein Function unknown 119382988 Common - hypothetical protein Pden_0234 33 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 119384998 Common - putative transcriptional regulator, AsnC family Pden_2266 164 COG1522 Lrp, Transcriptional regulators Transcription 119382838 Common - regulatory protein, LuxR Pden_0081 7 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 119385185 Common - protein phosphatase 2C domain protein Pden_2458 117 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 119385419 Common - Mammalian cell entry related domain protein Pden_2692 64 COG3008 PqiB, Paraquat-inducible protein B General function prediction only 119384844 Common - flagellar hook-basal body complex protein FliE Pden_2112 21 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 119385200 Common murQ N-acetylmuramic acid-6-phosphate etherase Pden_2473 86 COG2103 COG2103, Predicted sugar phosphate isomerase General function prediction only 119383856 Common - acyl-CoA synthetase Pden_1108 214 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 119383445 Common ruvB Holliday junction DNA helicase B Pden_0693 218 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 119385498 Nonpathogen - hypothetical protein Pden_2774 3 None None None 119384697 Common - hypothetical protein Pden_1965 21 None None None 119383790 Common - NIPSNAP family containing protein Pden_1039 20 None None None 119384699 Nonpathogen - hypothetical protein Pden_1967 2 None None None 119385044 Common - hypothetical protein Pden_2313 3 None None None 119384849 Common flgH flagellar basal body L-ring protein Pden_2117 99 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 119383481 Common - aminotransferase, class V Pden_0729 152 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 119383488 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pden_0736 58 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 119385118 Nonpathogen - hypothetical protein Pden_2389 1 None None None 119383052 Common - transport system permease protein Pden_0298 148 COG4605 CeuC, ABC-type enterochelin transport system, permease component Inorganic ion transport and metabolism 119383929 Common - proline racemase Pden_1184 47 COG3938 COG3938, Proline racemase Amino acid transport and metabolism 119384236 Common - major facilitator superfamily MFS_1 Pden_1496 108 None None None 119384569 Common - oligoendopeptidase, pepF/M3 family Pden_1832 89 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 119382924 Common - hypothetical protein Pden_0168 10 None None None 119384426 Common - nitric oxide dioxygenase Pden_1689 139 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 119384595 Nonpathogen - hypothetical protein Pden_1858 4 None None None 119384468 Common - sulfate transporter Pden_1731 160 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 119384837 Common - UbiC transcription regulator-associated domain protein Pden_2105 107 COG2188 PhnF, Transcriptional regulators Transcription 119383470 Common - polar amino acid ABC transporter, inner membrane subunit Pden_0718 170 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 119383558 Nonpathogen - hypothetical protein Pden_0806 1 None None None 119382887 Common - transcriptional regulator, XRE family Pden_0130 15 COG1476 COG1476, Predicted transcriptional regulators Transcription 119384462 Nonpathogen - hypothetical protein Pden_1725 1 None None None 119384883 Common - polyamine ABC trasnporter, periplasmic polyamine-binding protein Pden_2151 52 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 119385092 Common - pyrroloquinoline quinone biosynthesis protein PqqB Pden_2362 45 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 119382977 Common - Succinate-semialdehyde dehydrogenase (NAD(P)(+)) Pden_0223 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 119383514 Common rplB 50S ribosomal protein L2 Pden_0762 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 119383363 Common - dihydrolipoamide dehydrogenase Pden_0611 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 119384552 Common - peptide chain release factor 2 Pden_1815 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 119384589 Common - cation diffusion facilitator family transporter Pden_1852 203 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 119385244 Common - protein of unknown function DUF163 Pden_2517 165 COG1576 COG1576, Uncharacterized conserved protein Function unknown 119383068 Common - AmiS/UreI transporter Pden_0314 17 None None None 119384748 Common - protein of unknown function DUF214 Pden_2016 33 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 119383765 Common - periplasmic binding protein/LacI transcriptional regulator Pden_1014 126 COG1609 PurR, Transcriptional regulators Transcription 119384648 Common - hypothetical protein Pden_1914 11 None None None 119383212 Common - transposition protein, putative Pden_0459 11 COG4987 CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 119382929 Common - fumarylacetoacetate (FAA) hydrolase Pden_0173 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 119384670 Common - cytochrome c, class I Pden_1937 32 COG3474 COG3474, Cytochrome c2 Energy production and conversion 119383446 Common - peptidase M48, Ste24p Pden_0694 195 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 119384887 Common - short chain dehydrogenase Pden_2155 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119383435 Common - MotA/TolQ/ExbB proton channel Pden_0683 132 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 119385441 Common - lipoprotein signal peptidase Pden_2717 189 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 119383042 Common - Succinylglutamate desuccinylase/aspartoacylase Pden_0288 51 COG3608 COG3608, Predicted deacylase General function prediction only 119383501 Common - DNA-directed RNA polymerase subunit beta' Pden_0749 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 119385275 Nonpathogen - hypothetical protein Pden_2548 6 None None None 119383738 Common - Resolvase helix-turn-helix domain protein Pden_0987 7 None None None 119382935 Common - ABC transporter related Pden_0179 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 119383751 Common - phage tape measure protein Pden_1000 31 COG3941 COG3941, Mu-like prophage protein General function prediction only 119382786 Common - ABC transporter related Pden_0029 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 119383749 Nonpathogen - hypothetical protein Pden_0998 3 None None None 119383315 Common - Citryl-CoA lyase Pden_0563 111 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 119385221 Common - Radical SAM domain protein Pden_2494 166 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 119385059 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pden_2328 40 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 119385196 Common - ABC transporter related Pden_2469 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 119383327 Common - glutamyl-tRNA(Gln) amidotransferase, C subunit Pden_0575 157 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 119384240 Common - helix-turn-helix- domain containing protein, AraC type Pden_1500 46 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 119383144 Common - protein of unknown function DUF983 Pden_0390 25 COG5349 COG5349, Uncharacterized protein conserved in bacteria Function unknown 119385437 Common mutL DNA mismatch repair protein Pden_2713 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 119385287 Common - enoyl-CoA hydratase Pden_2560 136 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 119383584 Common - ABC transporter related Pden_0832 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 119385474 Common - SMP-30/Gluconolaconase/LRE domain protein Pden_2750 66 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 119384249 Common - protein of unknown function DUF736 Pden_1509 25 COG5489 COG5489, Uncharacterized conserved protein Function unknown 119383004 Common - DNA-binding transcriptional repressor RpiR Pden_0250 113 COG1737 RpiR, Transcriptional regulators Transcription 119382796 Common thiG thiazole synthase Pden_0039 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 119382856 Nonpathogen - hypothetical protein Pden_0099 9 None None None 119384390 Common - lytic murein transglycosylase Pden_1653 106 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 119385499 Common - aspartate-semialdehyde dehydrogenase Pden_2775 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 119384227 Common - Methyltransferase type 12 Pden_1487 11 None None None 119383162 Common - Helix-turn-helix, type 11 domain protein Pden_0408 86 COG2378 COG2378, Predicted transcriptional regulator Transcription 119383134 Nonpathogen - hypothetical protein Pden_0380 1 None None None 119383059 Nonpathogen - hypothetical protein Pden_0305 1 None None None 119384902 Common ilvH acetolactate synthase 3 regulatory subunit Pden_2170 190 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 119383359 Common - binding-protein-dependent transport systems inner membrane component Pden_0607 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 119384700 Nonpathogen - hypothetical protein Pden_1968 1 None None None 119385462 Common - chromosome segregation protein SMC Pden_2738 175 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 119383249 Common - threonine dehydratase Pden_0497 201 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 119385384 Common - hypothetical protein Pden_2657 20 None None None 119384627 Common - putative hemolysin Pden_1892 60 COG3176 COG3176, Putative hemolysin General function prediction only 119383942 Common - NADH:flavin oxidoreductase/NADH oxidase Pden_1197 191 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 119383320 Common - putative succinate dehydrogenase, hydrophobic membrane anchor protein Pden_0568 33 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 119383970 Nonpathogen - hypothetical protein Pden_1225 1 None None None 119383070 Common - glycosyl transferase, family 2 Pden_0316 25 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 119385080 Common - hypothetical protein Pden_2350 14 None None None 119384620 Common - hypothetical protein Pden_1885 21 COG4731 COG4731, Uncharacterized protein conserved in bacteria Function unknown 119383542 Common - pseudouridine synthase, RluA family Pden_0790 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 119384075 Common - Cysteinyl-tRNA synthetase-like Pden_1330 141 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 119383523 Common rplE 50S ribosomal protein L5 Pden_0771 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 119384946 Common - protein of unknown function DUF526 Pden_2214 33 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 119385147 Common - phage integrase family protein Pden_2419 28 COG5236 COG5236, Uncharacterized conserved protein, contains RING Zn-finger General function prediction only 119383683 Common - 3-hydroxybutyrate dehydrogenase Pden_0932 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119383307 Common kgd alpha-ketoglutarate decarboxylase Pden_0555 148 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 119384978 Common - NADH dehydrogenase subunit E Pden_2246 155 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 119384854 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Pden_2122 162 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 119383425 Common - regulatory protein, LacI Pden_0673 125 COG1609 PurR, Transcriptional regulators Transcription 119384352 Common - ChaC family protein Pden_1612 44 COG3703 ChaC, Uncharacterized protein involved in cation transport Inorganic ion transport and metabolism 119383801 Common - ABC transporter related Pden_1050 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 119383180 Common - transcription elongation factor GreA Pden_0426 204 COG0782 GreA, Transcription elongation factor Transcription 119383386 Common - phosphate transporter Pden_0634 68 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 119383718 Common - hypothetical protein Pden_0967 5 None None None 119385140 Common - type I secretion membrane fusion protein, HlyD family Pden_2412 125 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 119382908 Common - hypothetical protein Pden_0151 11 None None None 119383914 Common - transport system permease protein Pden_1169 185 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 119383646 Common - modification methylase, HemK family Pden_0895 221 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 119384559 Common - 5-aminolevulinate synthase Pden_1822 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 119385340 Common purU formyltetrahydrofolate deformylase Pden_2613 218 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 119383498 Common rplL 50S ribosomal protein L7/L12 Pden_0746 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 119382916 Nonpathogen - hypothetical protein Pden_0159 1 None None None 119385296 Common - ABC transporter related Pden_2569 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 119383705 Common - putative cold-shock DNA-binding domain protein Pden_0954 179 COG1278 CspC, Cold shock proteins Transcription 119384220 Common - conjugal transfer protein TrbJ Pden_1480 25 COG5314 COG5314, Conjugal transfer/entry exclusion protein Intracellular trafficking and secretion 119383979 Common - capsule polysaccharide export protein-like Pden_1234 41 COG3524 KpsE, Capsule polysaccharide export protein Cell envelope biogenesis, outer membrane 119384263 Common - putative restriction endonuclease Pden_1523 33 COG3440 COG3440, Predicted restriction endonuclease Defense mechanisms 119384387 Common - beta-ketoacyl synthase Pden_1650 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 119383165 Common - putative exonuclease protein involved in mRNA processing Pden_0411 74 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 119383836 Common - binding-protein-dependent transport systems inner membrane component Pden_1088 155 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 119383592 Common - glycosyl transferase, group 1 Pden_0840 217 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 119383642 Common rpsF 30S ribosomal protein S6 Pden_0891 196 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 119384518 Common - transporter, hydrophobe/amphiphile efflux-1 (HAE1) family Pden_1781 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 119384612 Common - single-stranded-DNA-specific exonuclease RecJ Pden_1877 196 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 119383079 Common - protein of unknown function DUF886 Pden_0325 40 COG3758 COG3758, Uncharacterized protein conserved in bacteria Function unknown 119385038 Common - cytochrome c1 Pden_2307 73 COG2857 CYT1, Cytochrome c1 Energy production and conversion 119385282 Common pyrB aspartate carbamoyltransferase catalytic subunit Pden_2555 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 119385109 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pden_2379 41 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 119383700 Common - DNA/RNA non-specific endonuclease Pden_0949 23 COG1864 NUC1, DNA/RNA endonuclease G, NUC1 Nucleotide transport and metabolism 119385555 Common - ferredoxin Pden_2831 140 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 119383655 Common - DNA polymerase III subunit chi Pden_0904 34 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 119385387 Common - hypothetical protein Pden_2660 25 COG4246 COG4246, Uncharacterized protein conserved in bacteria Function unknown 119382992 Common - binding-protein-dependent transport systems inner membrane component Pden_0238 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 119383454 Common - monovalent cation/proton antiporter, MnhG/PhaG subunit Pden_0702 43 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 119382771 Common - protein of unknown function DUF454 Pden_0014 47 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 119383961 Common - Activator of Hsp90 ATPase 1 family protein Pden_1216 46 COG3832 COG3832, Uncharacterized conserved protein Function unknown 119384093 Common - thioesterase superfamily protein Pden_1349 77 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 119384214 Common - hypothetical protein Pden_1474 23 COG5639 COG5639, Uncharacterized conserved small protein Function unknown 119384435 Common - fructose-1,6-bisphosphate aldolase Pden_1698 171 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 119384709 Nonpathogen - hypothetical protein Pden_1977 1 COG4387 COG4387, Mu-like prophage protein gp36 Function unknown 119383220 Common - binding-protein-dependent transport systems inner membrane component Pden_0468 132 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 119383465 Common - L-carnitine dehydratase/bile acid-inducible protein F Pden_0713 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 119383947 Common - Resolvase, N-terminal domain Pden_1202 142 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 119383265 Nonpathogen - conserved hypoothetical protein Pden_0513 1 None None None 119384894 Common - xylulokinase Pden_2162 183 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 119383112 Common - Resolvase helix-turn-helix domain protein Pden_0358 7 None None None 119383426 Common - Xanthine/uracil/vitamin C permease Pden_0674 124 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 119383097 Nonpathogen - hypothetical protein Pden_0343 1 None None None 119384604 Common - chromosome segregation and condensation protein ScpA Pden_1867 115 COG1354 COG1354, Uncharacterized conserved protein Function unknown 119384656 Common - hypothetical protein Pden_1922 3 None None None 119382950 Common - hypothetical protein Pden_0194 30 COG3777 COG3777, Uncharacterized conserved protein Function unknown 119384017 Common - acetyl-CoA carboxylase, biotin carboxyl carrier protein Pden_1272 190 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 119385467 Common - elongation factor P Pden_2743 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 119384347 Common - MaoC domain protein dehydratase Pden_1607 54 COG2030 MaoC, Acyl dehydratase Lipid metabolism 119383107 Common - phage/plasmid primase, P4 family Pden_0353 46 COG3378 COG3378, Predicted ATPase General function prediction only 119384765 Common - penicillin-binding protein, 1A family Pden_2033 202 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 119384768 Common - type I secretion system ATPase Pden_2036 249 COG4618 ArpD, ABC-type protease/lipase transport system, ATPase and permease components General function prediction only 119385133 Common - hypothetical protein Pden_2405 14 None None None 119382768 Common - putative deoxyribonucleotide triphosphate pyrophosphatase Pden_0011 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 119384010 Common - Endopeptidase Clp Pden_1265 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 119385537 Common - shikimate 5-dehydrogenase Pden_2813 223 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 119383082 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pden_0328 39 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 119383100 Nonpathogen - hypothetical protein Pden_0346 1 None None None 119383737 Nonpathogen - hypothetical protein Pden_0986 1 None None None 119385100 Common - peptidase S16, lon domain protein Pden_2370 95 COG2802 COG2802, Uncharacterized protein, similar to the N-terminal domain of Lon protease General function prediction only 119385188 Common - filamentous haemagglutinin family outer membrane protein Pden_2461 60 COG3096 MukB, Uncharacterized protein involved in chromosome partitioning Cell division and chromosome partitioning 119382844 Common - acylneuraminate cytidylyltransferase Pden_0087 75 COG1083 NeuA, CMP-N-acetylneuraminic acid synthetase Cell envelope biogenesis, outer membrane 119384176 Common - glutamine amidotransferase class-I Pden_1435 55 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 119384183 Nonpathogen - hypothetical protein Pden_1442 1 None None None 119384682 Common pgi glucose-6-phosphate isomerase Pden_1950 199 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 119384155 Common - protein of unknown function DUF498 Pden_1414 31 COG3737 COG3737, Uncharacterized conserved protein Function unknown 119384910 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pden_2178 91 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 119384691 Common hisD histidinol dehydrogenase Pden_1959 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 119384043 Common - GDP-mannose 4,6-dehydratase Pden_1298 227 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 119384816 Nonpathogen - hypothetical protein Pden_2084 1 None None None 119385339 Common - sulphate transporter Pden_2612 161 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 119382945 Common - TRAP C4-dicarboxylate transport system permease DctM subunit Pden_0189 125 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 119385452 Nonpathogen - hypothetical protein Pden_2728 2 None None None 119384941 Common - putative transcriptional regulator, AsnC family Pden_2209 160 COG1522 Lrp, Transcriptional regulators Transcription 119385298 Common - Three-deoxy-D-manno-octulosonic-acid transferase domain protein Pden_2571 115 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 119383571 Nonpathogen - putative anti-sigma regulatory factor, serine/threonine protein kinase Pden_0819 7 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 119383208 Common - helix-turn-helix domain protein Pden_0455 30 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 119383276 Common - purine nucleoside phosphorylase Pden_0524 157 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 119384728 Nonpathogen - hypothetical protein Pden_1996 7 COG4223 COG4223, Uncharacterized protein conserved in bacteria Function unknown 119384254 Common - hypothetical protein Pden_1514 10 COG5419 COG5419, Uncharacterized conserved protein Function unknown 119384378 Common - conserved hypothetical protein 698 Pden_1641 114 COG2855 COG2855, Predicted membrane protein Function unknown 119384634 Common - Substrate-binding region of ABC-type glycine betaine transport system Pden_1899 61 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 119384020 Common - transketolase Pden_1275 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 119383740 Common - phage portal protein, HK97 family Pden_0989 66 COG4695 COG4695, Phage-related protein Function unknown 119384536 Common - sulfate ABC transporter, inner membrane subunit CysT Pden_1799 228 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 119384371 Common - uncharacterized enzyme Pden_1633 60 COG2170 COG2170, Uncharacterized conserved protein Function unknown 119383050 Common - TonB-dependent receptor Pden_0296 42 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 119384269 Common - hypothetical protein Pden_1529 36 COG2378 COG2378, Predicted transcriptional regulator Transcription 119385527 Common - beta-lactamase domain protein Pden_2803 79 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 119382778 Common - hypothetical protein Pden_0021 12 None None None 119385049 Common - transcriptional regulator, LysR family Pden_2318 188 COG0583 LysR, Transcriptional regulator Transcription 119385192 Common - Hemolysin-type calcium-binding region Pden_2465 90 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 119384805 Nonpathogen - hypothetical protein Pden_2073 1 None None None 119384917 Common - glycoside hydrolase, family 25 Pden_2185 45 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 119384687 Common - phosphogluconate dehydratase Pden_1955 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 119383121 Common - hypothetical protein Pden_0367 3 None None None 119383415 Common - TRAP transporter, 4TM/12TM fusion protein Pden_0663 128 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 119384821 Common - hypothetical protein Pden_2089 12 None None None 119384324 Nonpathogen - hypothetical protein Pden_1584 1 None None None 119384286 Common - ORF-3 family protein Pden_1546 47 None None None 119383344 Common - inosine-5'-monophosphate dehydrogenase Pden_0592 236 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 119385515 Common - ATP-dependent protease peptidase subunit Pden_2791 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 119383190 Common - protein of unknown function DUF179 Pden_0436 131 COG1678 COG1678, Putative transcriptional regulator Transcription 119385219 Common - putative transcriptional regulator, AsnC family Pden_2492 48 COG1522 Lrp, Transcriptional regulators Transcription 119384956 Common - malic enzyme Pden_2224 216 COG0281 SfcA, Malic enzyme Energy production and conversion 119383397 Common - peptide deformylase Pden_0645 212 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 119384543 Common - binding-protein-dependent transport systems inner membrane component Pden_1806 219 COG4174 COG4174, ABC-type uncharacterized transport system, permease component General function prediction only 119384277 Common - hypothetical protein Pden_1537 4 None None None 119384802 Common - hypothetical protein Pden_2070 9 None None None 119383028 Common - hypothetical protein Pden_0274 12 COG1340 COG1340, Uncharacterized archaeal coiled-coil protein Function unknown 119383099 Nonpathogen - hypothetical protein Pden_0345 1 None None None 119385333 Common - OstA family protein Pden_2606 44 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 119385130 Nonpathogen - hypothetical protein Pden_2402 1 None None None 119383601 Common - putative outer membrane protein Pden_0849 14 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 119383670 Nonpathogen - hypothetical protein Pden_0919 1 None None None 119384586 Common - UspA domain protein Pden_1849 37 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 119384842 Common flgB flagellar basal body rod protein FlgB Pden_2110 37 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 119385319 Common nusA transcription elongation factor NusA Pden_2592 220 COG0195 NusA, Transcription elongation factor Transcription 119385316 Common - 3-demethylubiquinone-9 3-methyltransferase Pden_2589 163 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 119385259 Common cobN cobaltochelatase Pden_2532 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 119383173 Common - Ribonuclease III Pden_0419 216 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 119384114 Common - ATP-dependent Lon protease Pden_1373 177 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 119383968 Common - phage integrase family protein Pden_1223 24 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 119385171 Common - protein of unknown function DUF877 Pden_2444 50 COG3517 COG3517, Uncharacterized protein conserved in bacteria Function unknown 119382903 Common - hypothetical protein Pden_0146 23 COG5639 COG5639, Uncharacterized conserved small protein Function unknown 119385280 Common - protein of unknown function DUF205 Pden_2553 170 COG0344 COG0344, Predicted membrane protein Function unknown 119384029 Common - monovalent cation/proton antiporter, MnhG/PhaG subunit Pden_1284 29 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 119384452 Common - ABC transporter related Pden_1715 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 119385291 Common entF enterobactin synthase subunit F Pden_2564 214 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 119383215 Common - IstB domain protein ATP-binding protein Pden_0462 80 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 119383845 Nonpathogen - hypothetical protein Pden_1097 2 None None None 119384919 Common - D-lactate dehydrogenase (cytochrome) Pden_2187 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 119383982 Nonpathogen - hypothetical protein Pden_1237 5 None None None 119384205 Common - hypothetical protein Pden_1465 43 COG0730 COG0730, Predicted permeases General function prediction only 119385483 Common - polynucleotide phosphorylase/polyadenylase Pden_2759 242 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 119385024 Nonpathogen - glycosyl transferase, family 14 Pden_2293 8 None None None 119384306 Common - cobalamin 5'-phosphate synthase Pden_1566 76 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 119382823 Common - hypothetical protein Pden_0066 25 COG4889 COG4889, Predicted helicase General function prediction only 119384524 Nonpathogen - hypothetical protein Pden_1787 1 None None None 119382922 Common - regulatory protein, ArsR Pden_0166 69 COG0640 ArsR, Predicted transcriptional regulators Transcription 119383178 Common - Tetratricopeptide TPR_2 repeat protein Pden_0424 138 COG4785 NlpI, Lipoprotein NlpI, contains TPR repeats General function prediction only 119383197 Common - protein of unknown function DUF955 Pden_0443 37 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 119382801 Common - hypothetical protein Pden_0044 53 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 119384368 Common - putative FecR Pden_1630 41 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 119383323 Nonpathogen - hypothetical protein Pden_0571 2 None None None 119384507 Common - malonyl CoA-acyl carrier protein transacylase Pden_1770 208 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 119384969 Common - Carboxymuconolactone decarboxylase Pden_2237 73 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 119382774 Common - Endopeptidase Clp Pden_0017 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 119384052 Nonpathogen - hypothetical protein Pden_1307 1 None None None 119383503 Common - protein of unknown function DUF6, transmembrane Pden_0751 33 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 119384260 Nonpathogen - hypothetical protein Pden_1520 12 None None None 119384562 Common - transcriptional regulator, CarD family Pden_1825 84 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 119382941 Common - hypothetical protein Pden_0185 7 None None None 119383742 Common - phage major capsid protein, HK97 family Pden_0991 17 COG4653 COG4653, Predicted phage phi-C31 gp36 major capsid-like protein General function prediction only 119382888 Common - hypothetical protein Pden_0131 25 None None None 119384061 Common - hypothetical protein Pden_1316 28 COG4645 COG4645, Uncharacterized protein conserved in bacteria Function unknown 119382818 Common - hypothetical protein Pden_0061 4 None None None 119383269 Nonpathogen - hypothetical protein Pden_0517 1 None None None 119384131 Common - protein of unknown function UPF0005 Pden_1390 134 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 119385235 Common - carboxyl-terminal protease Pden_2508 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 119383699 Common - acyl-CoA dehydrogenase domain protein Pden_0948 146 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 119384312 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Pden_1572 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 119383450 Common - putative monovalent cation/H+ antiporter subunit C Pden_0698 92 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 119382948 Common - short-chain dehydrogenase/reductase SDR Pden_0192 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119383376 Common - protein of unknown function DUF558 Pden_0624 194 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 119384786 Nonpathogen - hypothetical protein Pden_2054 3 None None None 119383088 Common - translation-associated GTPase Pden_0334 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 119385373 Common - hypothetical protein Pden_2646 9 COG3334 COG3334, Uncharacterized conserved protein Function unknown 119384007 Common - hypothetical protein Pden_1262 42 COG3651 COG3651, Uncharacterized protein conserved in bacteria Function unknown 119383317 Common - hypothetical protein Pden_0565 19 COG5515 COG5515, Uncharacterized conserved small protein Function unknown 119385137 Nonpathogen - hypothetical protein Pden_2409 1 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 119384361 Nonpathogen - hypothetical protein Pden_1622 3 None None None 119383034 Common - ABC transporter related Pden_0280 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 119383233 Common - hypothetical protein Pden_0481 8 None None None 119383353 Nonpathogen - hypothetical protein Pden_0601 1 None None None 119385016 Common - Substrate-binding region of ABC-type glycine betaine transport system Pden_2285 62 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 119382869 Common - hypothetical protein Pden_0112 8 None None None 119384991 Common - ribonuclease T2 Pden_2259 38 COG3719 Rna, Ribonuclease I Translation, ribosomal structure and biogenesis 119382893 Common - protein of unknown function DUF736 Pden_0136 33 COG4959 TraF, Type IV secretory pathway, protease TraF Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 119383518 Common rplP 50S ribosomal protein L16 Pden_0766 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 119383822 Common - polar amino acid ABC transporter, inner membrane subunit Pden_1073 170 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 119384726 Nonpathogen - hypothetical protein Pden_1994 1 None None None 119384877 Common - DNA polymerase III subunit delta' Pden_2145 103 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 119384178 Common - pyridoxal kinase Pden_1437 161 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 119383258 Common - ROK family protein Pden_0506 44 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 119383924 Common - oxidoreductase FAD/NAD(P)-binding domain protein Pden_1179 180 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 119384086 Common - extracellular solute-binding protein, family 5 Pden_1341 176 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 119385305 Common - hypothetical protein Pden_2578 69 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 119384397 Common - two component transcriptional regulator, winged helix family Pden_1660 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 119383389 Common - penicillin-binding protein 1C Pden_0637 199 COG4953 PbpC, Membrane carboxypeptidase/penicillin-binding protein PbpC Cell envelope biogenesis, outer membrane 119384914 Common - hypothetical protein Pden_2182 41 COG5267 COG5267, Uncharacterized protein conserved in bacteria Function unknown 119384740 Common - putative ABC transporter ATP-binding protein Pden_2008 248 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 119382999 Common - 5-carboxymethyl-2-hydroxymuconate delta-isomerase Pden_0245 177 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 119384345 Common - flavoprotein Pden_1605 76 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 119383546 Common - polar amino acid ABC transporter, inner membrane subunit Pden_0794 172 COG4597 BatB, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 119385232 Common - radical SAM enzyme, Cfr family Pden_2505 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 119382981 Nonpathogen - hypothetical protein Pden_0227 1 None None None 119384685 Common - hypothetical protein Pden_1953 33 None None None 119384164 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Pden_1423 128 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 119384534 Common - sulfate ABC transporter, ATPase subunit Pden_1797 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 119385363 Common - phage prohead protease, HK97 family Pden_2636 9 COG3740 COG3740, Phage head maturation protease General function prediction only 119384973 Common - NADH dehydrogenase subunit G Pden_2241 187 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 119383407 Common - nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein Pden_0655 166 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 119384292 Nonpathogen - hypothetical protein Pden_1552 3 None None None 119383888 Common - periplasmic binding protein Pden_1140 39 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 119384358 Common - flagellar FlaF family protein Pden_1619 11 COG5442 FlaF, Flagellar biosynthesis regulator FlaF Cell motility and secretion 119383939 Common - binding-protein-dependent transport systems inner membrane component Pden_1194 219 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 119383483 Common - glycine cleavage T protein (aminomethyl transferase) Pden_0731 94 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 119384149 Common - cyclohexadienyl dehydrogenase Pden_1408 155 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 119385496 Common - major facilitator superfamily MFS_1 Pden_2772 49 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 119384896 Common - GatB/Yqey domain protein Pden_2164 152 COG1610 COG1610, Uncharacterized conserved protein Function unknown 119385065 Nonpathogen - NnrUfamily protein Pden_2334 3 COG4094 COG4094, Predicted membrane protein Function unknown 119384864 Common - anthranilate synthase component I Pden_2132 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 119385202 Common - UbiC transcription regulator-associated domain protein Pden_2475 141 COG2188 PhnF, Transcriptional regulators Transcription 119383443 Nonpathogen - Chorismate mutase Pden_0691 12 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 119382829 Common - CHAD domain containing protein Pden_0072 56 COG5607 COG5607, Uncharacterized conserved protein Function unknown 119384234 Common - monooxygenase, FAD-binding Pden_1494 42 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 119385541 Common - glutathione-dependent formaldehyde-activating, GFA Pden_2817 60 COG3791 COG3791, Uncharacterized conserved protein Function unknown 119384772 Common - GCN5-related N-acetyltransferase Pden_2040 17 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 119385002 Common - phenylalanyl-tRNA synthetase, alpha subunit Pden_2270 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 119385521 Common - protein of unknown function UPF0079 Pden_2797 193 COG3178 COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases General function prediction only 119384593 Common - histidine triad (HIT) protein Pden_1856 208 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 119382867 Nonpathogen - hypothetical protein Pden_0110 1 None None None 119383392 Common - ATP-dependent helicase HrpB Pden_0640 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 119383310 Common - succinyl-CoA synthetase, alpha subunit Pden_0558 206 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 119382975 Common - hypothetical protein Pden_0221 32 COG3777 COG3777, Uncharacterized conserved protein Function unknown 119383624 Nonpathogen - ribonuclease P protein component Pden_0873 21 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 119383008 Nonpathogen - hypothetical protein Pden_0254 1 None None None 119383949 Common - D-alanine--D-alanine ligase Pden_1204 210 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 119384466 Common - alanine dehydrogenase Pden_1729 151 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 119385033 Common - chaperone protein DnaK Pden_2302 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 119385455 Common - stationary-phase survival protein SurE Pden_2731 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 119383222 Common - transcriptional regulator, GntR family Pden_0470 118 COG1802 GntR, Transcriptional regulators Transcription 119385227 Nonpathogen - hypothetical protein Pden_2500 11 COG3159 COG3159, Uncharacterized protein conserved in bacteria Function unknown 119385209 Common - ATPase associated with various cellular activities, AAA_5 Pden_2482 92 COG0714 COG0714, MoxR-like ATPases General function prediction only 119384985 Common - glutathione-dependent formaldehyde-activating, GFA Pden_2253 54 COG3791 COG3791, Uncharacterized conserved protein Function unknown 119384198 Common - Cupin 2, conserved barrel domain protein Pden_1458 21 COG3837 COG3837, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 119384614 Common carB carbamoyl phosphate synthase large subunit Pden_1879 235 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 119382817 Common - orotidine 5'-phosphate decarboxylase Pden_0060 151 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 119385348 Common - periplasmic binding protein/LacI transcriptional regulator Pden_2621 126 COG1609 PurR, Transcriptional regulators Transcription 119385099 Common - protein of unknown function DUF343 Pden_2369 84 COG2835 COG2835, Uncharacterized conserved protein Function unknown 119384482 Common - cytochrome B561 Pden_1745 80 COG3038 CybB, Cytochrome B561 Energy production and conversion 119385013 Nonpathogen - Arc domain protein DNA binding domain protein Pden_2281 2 None None None 119385211 Common - Nitric-oxide reductase Pden_2484 35 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 119384475 Common - creatinase Pden_1738 121 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 119385406 Common - surface antigen (D15) Pden_2679 115 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 119384960 Common - beta-lactamase domain protein Pden_2228 156 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 119384715 Nonpathogen - hypothetical protein Pden_1983 4 None None None 119385356 Nonpathogen - hypothetical protein Pden_2629 1 None None None 119383126 Common - hypothetical protein Pden_0372 14 COG4678 COG4678, Muramidase (phage lambda lysozyme) Carbohydrate transport and metabolism 119384165 Common - Methyltransferase type 11 Pden_1424 16 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 119382885 Nonpathogen - hypothetical protein Pden_0128 1 None None None 119385422 Common - putative chemotaxis MotB protein Pden_2695 76 COG1360 MotB, Flagellar motor protein Cell motility and secretion 119383045 Common - Alcohol dehydrogenase, zinc-binding domain protein Pden_0291 153 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 119384873 Common - molybdenum cofactor synthesis domain Pden_2141 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 119383999 Common - aldehyde dehydrogenase Pden_1254 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 119384032 Common - putative monovalent cation/H+ antiporter subunit D Pden_1287 202 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 119382912 Common - Conjugal transfer protein TrbC Pden_0155 23 COG3838 VirB2, Type IV secretory pathway, VirB2 components (pilins) Intracellular trafficking and secretion 119384934 Common - phosphoribosylaminoimidazole carboxylase, catalytic subunit Pden_2202 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 119383990 Common - 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase Pden_1245 125 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 119383309 Nonpathogen - hypothetical protein Pden_0557 1 None None None 119384247 Common - hypothetical protein Pden_1507 26 COG3843 VirD2, Type IV secretory pathway, VirD2 components (relaxase) Intracellular trafficking and secretion 119384928 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Pden_2196 230 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 119384580 Common - FixH family protein Pden_1843 25 COG5456 COG5456, Predicted integral membrane protein linked to a cation pump Inorganic ion transport and metabolism 119382872 Common - yecA family protein Pden_0115 76 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 119383262 Common - Holliday junction resolvase YqgF Pden_0510 183 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 119384223 Common - Conjugal transfer protein TrbC Pden_1483 24 COG3838 VirB2, Type IV secretory pathway, VirB2 components (pilins) Intracellular trafficking and secretion 119385504 Common - electron transport protein SCO1/SenC Pden_2780 103 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 119382794 Common - UBA/THIF-type NAD/FAD binding protein Pden_0037 210 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 119383950 Common - urease accessory protein UreG Pden_1205 141 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 119383457 Common - Lytic transglycosylase, catalytic Pden_0705 145 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 119385214 Common - Hydroxylamine reductase Pden_2487 20 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 119383352 Common - putative glutamine amidotransferase Pden_0600 58 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 119383773 Common - binding-protein-dependent transport systems inner membrane component Pden_1022 120 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 119383590 Common - amino acid adenylation domain Pden_0838 215 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 119384702 Common - putative pancortin-3 Pden_1970 4 None None None 119383862 Common cofG FO synthase subunit 1 Pden_1114 57 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 119383169 Common - outer membrane protein Pden_0415 19 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 119383644 Common - Cytochrome-c peroxidase Pden_0893 93 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 119385430 Nonpathogen - hypothetical protein Pden_2706 4 None None None 119383636 Nonpathogen - hypothetical protein Pden_0885 1 None None None 119383152 Common - exodeoxyribonuclease VII, small subunit Pden_0398 119 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 119385382 Common - acriflavin resistance protein Pden_2655 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 119383754 Nonpathogen - hypothetical protein Pden_1003 1 None None None 119383803 Common - Aldehyde dehydrogenase (NAD(+)) Pden_1054 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 119384948 Common - RNA polymerase factor sigma-32 Pden_2216 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 119384071 Common - binding-protein-dependent transport systems inner membrane component Pden_1326 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 119383927 Common - 3-oxoadipate enol-lactonase Pden_1182 129 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 119383764 Common - Succinate-semialdehyde dehydrogenase (NAD(P)(+)) Pden_1013 65 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 119383160 Common - protein of unknown function DUF6, transmembrane Pden_0406 145 None None None 119384575 Nonpathogen - phosphoesterase, PA-phosphatase related Pden_1838 1 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 119382906 Common - Conjugal transfer protein Pden_0149 30 COG3701 TrbF, Type IV secretory pathway, TrbF components Intracellular trafficking and secretion 119385158 Common - arginine/ornithine transport system ATPase Pden_2431 100 COG1703 ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family Amino acid transport and metabolism 119385265 Common - precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit Pden_2538 98 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 119384800 Common - ParB domain protein nuclease Pden_2068 37 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 119383411 Common - DNA topoisomerase I Pden_0659 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 119383384 Common smpB SsrA-binding protein Pden_0632 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 119383301 Common - GCN5-related N-acetyltransferase Pden_0549 62 COG0456 RimI, Acetyltransferases General function prediction only 119385520 Common - Nucleotidyl transferase Pden_2796 151 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 119383876 Common - von Willebrand factor, type A Pden_1128 70 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 119385273 Common - DNA topoisomerase IV subunit A Pden_2546 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 119384835 Common - Ureidoglycolate hydrolase Pden_2103 34 COG3194 DAL3, Ureidoglycolate hydrolase Nucleotide transport and metabolism 119384380 Common - FAD dependent oxidoreductase Pden_1643 104 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 119385067 Common - protein of unknown function DUF752 Pden_2336 76 COG4121 COG4121, Uncharacterized conserved protein Function unknown 119383785 Common - inner-membrane translocator Pden_1034 105 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 119383912 Common - molybdenum ABC transporter, periplasmic molybdate-binding protein Pden_1167 62 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 119385070 Common - acetyl-CoA carboxylase carboxyltransferase subunit alpha Pden_2339 177 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 119384330 Common - Cobyrinic acid a,c-diamide synthase Pden_1590 189 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 119382773 Common - Alcohol dehydrogenase GroES domain protein Pden_0016 187 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 119383599 Common - polysaccharide biosynthesis protein Pden_0847 68 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 119384406 Common - binding-protein-dependent transport systems inner membrane component Pden_1669 218 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 119384350 Common - binding-protein-dependent transport systems inner membrane component Pden_1610 69 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 119383479 Common - MotA/TolQ/ExbB proton channel Pden_0727 148 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 119383716 Nonpathogen - hypothetical protein Pden_0965 1 None None None 119384852 Common - dTDP-4-dehydrorhamnose reductase Pden_2120 163 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 119382765 Common - GrpE protein Pden_0008 186 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 119383525 Common rpsH 30S ribosomal protein S8 Pden_0773 243 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 119382788 Common - hypothetical protein Pden_0031 10 None None None 119383187 Common - beta-lactamase domain protein Pden_0433 71 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 119385094 Common - alpha-2-macroglobulin domain protein Pden_2364 82 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 119384557 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase Pden_1820 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 119383253 Common - molybdenum cofactor synthesis domain Pden_0501 188 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 119384881 Common - binding-protein-dependent transport systems inner membrane component Pden_2149 202 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 119383189 Common - Sua5/YciO/YrdC/YwlC family protein Pden_0435 231 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 119383830 Nonpathogen - dual specificity protein phosphatase Pden_1081 3 COG2453 CDC14, Predicted protein-tyrosine phosphatase Signal transduction mechanisms 119385325 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Pden_2598 161 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 119385190 Nonpathogen - hypothetical protein Pden_2463 1 None None None 119383119 Nonpathogen - hypothetical protein Pden_0365 1 None None None 119385242 Common - conserved hypothetical protein 730 Pden_2515 107 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 119384638 Common - Lysine exporter protein (LYSE/YGGA) Pden_1903 75 COG1279 COG1279, Lysine efflux permease General function prediction only 119384270 Nonpathogen - hypothetical protein Pden_1530 2 None None None 119385417 Common - hypothetical protein Pden_2690 14 None None None 119383490 Common - transferase hexapeptide repeat containing protein Pden_0738 68 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 119383689 Common - aminotransferase, class I and II Pden_0938 234 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 119385160 Common rpmB 50S ribosomal protein L28 Pden_2433 162 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 119383973 Common - putative transcriptional regulator, XRE family Pden_1228 3 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 119384926 Common - protein of unknown function DUF475 Pden_2194 40 COG2899 COG2899, Uncharacterized protein conserved in bacteria Function unknown 119384288 Common - HipA domain protein Pden_1548 55 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 119384076 Common - cobalamin synthesis protein, P47K Pden_1331 122 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 119384885 Common - spermidine/putrescine ABC transporter ATPase subunit Pden_2153 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 119385223 Nonpathogen - hypothetical protein Pden_2496 2 None None None 119383022 Nonpathogen - hypothetical protein Pden_0268 1 None None None 119383485 Common - hypothetical protein Pden_0733 39 COG2979 COG2979, Uncharacterized protein conserved in bacteria Function unknown 119382854 Nonpathogen - hypothetical protein Pden_0097 1 None None None 119383516 Common rplV 50S ribosomal protein L22 Pden_0764 214 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 119384363 Common - transposase IS3/IS911 family protein Pden_1624 14 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 119383015 Common - D12 class N6 adenine-specific DNA methyltransferase Pden_0261 60 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 119384299 Common - polysaccharide export protein Pden_1559 84 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 119383540 Common - recombination factor protein RarA Pden_0788 230 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 119384146 Common - hypothetical protein Pden_1405 28 None None None 119383146 Nonpathogen - hypothetical protein Pden_0392 2 None None None 119384174 Common - biotin synthase Pden_1433 173 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 119383668 Nonpathogen - Entericidin EcnAB Pden_0917 1 COG5510 COG5510, Predicted small secreted protein Function unknown 119383322 Nonpathogen - hypothetical protein Pden_0570 1 None None None 119383093 Common - hypothetical protein Pden_0339 4 None None None 119383576 Common - protein of unknown function DUF403 Pden_0824 82 COG2307 COG2307, Uncharacterized protein conserved in bacteria Function unknown 119382927 Common - monooxygenase, FAD-binding Pden_0171 40 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 119384794 Common - DNA mismatch endonuclease vsr Pden_2062 71 COG3727 Vsr, DNA G:T-mismatch repair endonuclease DNA replication, recombination, and repair 119384290 Common - protein of unknown function DUF1052 Pden_1550 30 COG5321 COG5321, Uncharacterized protein conserved in bacteria Function unknown 119385194 Common - response regulator receiver protein Pden_2467 6 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 119384502 Common - inner-membrane translocator Pden_1765 106 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 119384848 Common flgA flagellar basal body P-ring biosynthesis protein FlgA Pden_2116 30 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 119383556 Common - D-amino acid dehydrogenase small subunit Pden_0804 145 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 119384511 Common - periplasmic binding protein Pden_1774 32 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 119384318 Common - peptidase S13, D-Ala-D-Ala carboxypeptidase C Pden_1578 33 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 119385075 Common - heavy metal translocating P-type ATPase Pden_2344 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 119383854 Common - GntR domain protein Pden_1106 117 COG2186 FadR, Transcriptional regulators Transcription 119383794 Common - Cupin 2, conserved barrel domain protein Pden_1043 13 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 119385250 Common - hypothetical protein Pden_2523 22 None None None 119384403 Common - lysine 2,3-aminomutase YodO family protein Pden_1666 125 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 119384529 Common - ribonuclease Pden_1792 158 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 119385285 Common - SirA family protein Pden_2558 100 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 119383278 Common - inner-membrane translocator Pden_0526 105 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 119385369 Nonpathogen - hypothetical protein Pden_2642 1 None None None 119384623 Common hisE phosphoribosyl-ATP pyrophosphatase Pden_1888 156 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 119382972 Common - transcriptional regulator, LysR family Pden_0218 170 COG0583 LysR, Transcriptional regulator Transcription 119383060 Common - protein of unknown function DUF112, transmembrane Pden_0306 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 119384281 Common - parB-like partition proteins Pden_1541 141 COG1475 Spo0J, Predicted transcriptional regulators Transcription 119383565 Common - phosphoserine aminotransferase Pden_0813 62 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 119384693 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Pden_1961 216 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 119384229 Common - binding-protein-dependent transport systems inner membrane component Pden_1489 34 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 119384643 Common fumC fumarate hydratase Pden_1908 235 COG0114 FumC, Fumarase Energy production and conversion 119385454 Common - protein-L-isoaspartate O-methyltransferase Pden_2730 155 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 119384818 Common - RNA polymerase, sigma 32 subunit, RpoH Pden_2086 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 119382836 Common - two component transcriptional regulator, winged helix family Pden_0079 211 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 119384335 Common - ABC transporter related Pden_1595 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 119385042 Common - short chain dehydrogenase Pden_2311 227 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119383110 Common - HNH endonuclease Pden_0356 23 COG1403 McrA, Restriction endonuclease Defense mechanisms 119385472 Common - 2-keto-3-deoxy-galactonokinase Pden_2748 39 COG3734 DgoK, 2-keto-3-deoxy-galactonokinase Carbohydrate transport and metabolism 119382946 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Pden_0190 71 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 119384653 Nonpathogen - hypothetical protein Pden_1919 1 None None None 119383288 Common - cation transporter Pden_0536 132 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 119384491 Common - short-chain dehydrogenase/reductase SDR Pden_1754 213 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119384041 Common - DegT/DnrJ/EryC1/StrS aminotransferase Pden_1296 190 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 119384826 Common - tetraacyldisaccharide 4'-kinase Pden_2094 130 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 119385482 Nonpathogen - hypothetical protein Pden_2758 3 None None None 119384732 Common - YCII-related Pden_2000 50 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 119384310 Common - binding-protein-dependent transport systems inner membrane component Pden_1570 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 119385307 Common - Allergen V5/Tpx-1 family protein Pden_2580 43 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 119384958 Common - 3-phosphoshikimate 1-carboxyvinyltransferase Pden_2226 229 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 119384680 Nonpathogen - hypothetical protein Pden_1948 4 None None None 119385414 Common - peptidase U62, modulator of DNA gyrase Pden_2687 157 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 119385360 Common - phage Terminase Pden_2633 9 COG4626 COG4626, Phage terminase-like protein, large subunit General function prediction only 119385249 Common leuD isopropylmalate isomerase small subunit Pden_2522 212 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 119385047 Common - ABC transporter related Pden_2316 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 119384632 Common - betaine aldehyde dehydrogenase Pden_1897 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 119383840 Common - thiamine pyrophosphate enzyme domain protein TPP-binding Pden_1092 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 119383963 Nonpathogen - hypothetical protein Pden_1218 1 None None None 119382956 Common - flavin reductase domain protein, FMN-binding Pden_0202 93 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 119385107 Common - short-chain dehydrogenase/reductase SDR Pden_2377 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119383066 Common - protein of unknown function DUF475 Pden_0312 40 COG2899 COG2899, Uncharacterized protein conserved in bacteria Function unknown 119382766 Common hrcA heat-inducible transcription repressor Pden_0009 149 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 119384048 Common - Ppx/GppA phosphatase Pden_1303 180 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 119384216 Common - Conjugal transfer protein TrbG/VirB9/CagX Pden_1476 52 COG3504 VirB9, Type IV secretory pathway, VirB9 components Intracellular trafficking and secretion 119382990 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Pden_0236 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 119384031 Common - cation antiporter Pden_1286 43 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 119383919 Common - muconate and chloromuconate cycloisomerases Pden_1174 124 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 119384038 Common - serine acetyltransferase CysE, putative Pden_1293 202 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 119383640 Common rplI 50S ribosomal protein L9 Pden_0889 216 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 119385168 Common - protein kinase Pden_2441 137 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 119384750 Nonpathogen - MJ0042 family finger-like protein Pden_2018 11 COG5373 COG5373, Predicted membrane protein Function unknown 119383728 Nonpathogen - hypothetical protein Pden_0977 1 None None None 119385120 Common - Cyclopropane-fatty-acyl-phospholipid synthase Pden_2392 125 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 119384095 Common - LysR, substrate-binding Pden_1351 72 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 119385553 Common - formate dehydrogenase, alpha subunit Pden_2829 181 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 119384097 Common - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase Pden_1355 146 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 119383263 Common - putative cytochrome c-type biogenesis protein, CycH Pden_0511 36 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 119383238 Common - hypothetical protein Pden_0486 11 COG4190 COG4190, Predicted transcriptional regulator Transcription 119385263 Common - precorrin-3B C17-methyltransferase Pden_2536 117 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 119383036 Common - amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Pden_0282 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 119384054 Common - ETC complex I subunit conserved region Pden_1309 37 None None None 119384203 Common - transcriptional regulator, LysR family Pden_1463 135 COG0583 LysR, Transcriptional regulator Transcription 119384522 Common - helix-turn-helix domain protein Pden_1785 22 COG3800 COG3800, Predicted transcriptional regulator General function prediction only 119384443 Common - quinohemoprotein amine dehydrogenase, subunit beta Pden_1706 5 None None None 119383433 Nonpathogen - hypothetical protein Pden_0681 6 None None None 119383423 Common - beta-lactamase domain protein Pden_0671 19 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 119385505 Common - two component transcriptional regulator, Fis family Pden_2781 157 COG4567 COG4567, Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain Signal transduction mechanisms / Transcription 119384411 Common - Xylose isomerase domain protein TIM barrel Pden_1674 62 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 119384639 Common - chromosome replication initiation inhibitor protein Pden_1904 109 COG0583 LysR, Transcriptional regulator Transcription 119385469 Common - putative sugar uptake ABC transporter periplasmic solute-binding protein precursor Pden_2745 82 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 119383723 Nonpathogen - hypothetical protein Pden_0972 1 None None None 119383102 Nonpathogen - hypothetical protein Pden_0348 1 None None None 119384761 Common - methyltransferase small Pden_2029 67 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 119385128 Nonpathogen - hypothetical protein Pden_2400 1 None None None 119383735 Nonpathogen - hypothetical protein Pden_0984 2 None None None 119383002 Common - ABC transporter related Pden_0248 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 119382825 Common - transposase IS66 Pden_0068 61 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 119383814 Common - short-chain dehydrogenase/reductase SDR Pden_1065 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 119384629 Common - hypothetical protein Pden_1894 29 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 119385539 Common - DNA polymerase III, epsilon subunit Pden_2815 188 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair