Mesorhizobium sp. BNC1, complete genome NC_008254 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 110634529 Common - hypothetical protein Meso_2180 67 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 110632509 Common - Secreted repeat of unknown function Meso_0147 36 COG4315 COG4315, Uncharacterized protein conserved in bacteria Function unknown 110635645 Common holA DNA polymerase III subunit delta Meso_3317 52 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 110635957 Common - NADH:flavin oxidoreductase/NADH oxidase Meso_3631 195 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 110632788 Common - CMP/dCMP deaminase, zinc-binding Meso_0427 197 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 110635153 Common - xylose isomerase Meso_2820 73 COG2115 XylA, Xylose isomerase Carbohydrate transport and metabolism 110634921 Common - amino acid adenylation domain Meso_2580 242 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 110633379 Common - NADH dehydrogenase subunit D Meso_1025 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 110633486 Common - Twin-arginine translocation pathway signal Meso_1133 74 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 110634518 Common - coproporphyrinogen III oxidase Meso_2169 113 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 110633390 Common - biotin--acetyl-CoA-carboxylase ligase Meso_1036 217 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 110634024 Common rpsC 30S ribosomal protein S3 Meso_1672 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 110633014 Common - glycosyl transferase, family 2 Meso_0657 53 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 110634695 Nonpathogen - hypothetical protein Meso_2351 2 None None None 110632587 Common - hypothetical protein Meso_0226 2 None None None 110636124 Common - putative RNA methylase Meso_3799 37 COG1041 COG1041, Predicted DNA modification methylase DNA replication, recombination, and repair 110633183 Common - ABC transporter related Meso_0826 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 110636192 Common - protein of unknown function DUF305 Meso_3868 48 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 110635166 Common - molybdopterin dehydrogenase, FAD-binding Meso_2833 123 COG4630 XdhA, Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A Nucleotide transport and metabolism 110634100 Common - HflK protein Meso_1749 186 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 110632738 Common - transferase hexapeptide repeat Meso_0377 167 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 110633667 Common - ErfK/YbiS/YcfS/YnhG Meso_1314 29 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 110634939 Common - hypothetical protein Meso_2598 6 None None None 110633281 Nonpathogen - hypothetical protein Meso_0927 1 None None None 110635992 Common - RNA polymerase factor sigma-54 Meso_3667 144 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 110634425 Common - protein of unknown function UPF0118 Meso_2075 200 COG0628 PerM, Predicted permease General function prediction only 110633040 Common - orotidine 5'-phosphate decarboxylase Meso_0683 170 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 110634555 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Meso_2206 122 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 110632608 Common - serine protease DO-like precursor Meso_0247 217 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 110633235 Common - Peptidoglycan-binding domain 1 Meso_0878 16 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 110635617 Common - protein of unknown function DUF1468 Meso_3289 24 None None None 110633403 Common - 6-phosphogluconate dehydrogenase, NAD-binding Meso_1049 34 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 110633781 Common - alanine dehydrogenase Meso_1428 167 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 110633576 Common - hypothetical protein Meso_1223 5 None None None 110635817 Common - hypothetical protein Meso_3489 6 None None None 110633948 Common - hypothetical protein Meso_1596 25 COG5477 COG5477, Predicted small integral membrane protein Function unknown 110634161 Common - glycoside hydrolase, family 3-like Meso_1810 168 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 110633050 Common - OsmC-like protein Meso_0693 33 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 110634522 Common - ABC transporter related Meso_2173 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 110634165 Common - deoxyguanosinetriphosphate triphosphohydrolase-like protein Meso_1814 159 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 110634117 Common - 3-oxoacyl-(acyl carrier protein) synthase II Meso_1766 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110634603 Common - cytochrome oxidase maturation protein, cbb3-type Meso_2256 25 COG3197 FixS, Uncharacterized protein, possibly involved in nitrogen fixation Inorganic ion transport and metabolism 110633200 Common - oxidoreductase-like Meso_0843 135 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 110632580 Nonpathogen - hypothetical protein Meso_0219 2 None None None 110634932 Common - glycosyl transferase, family 2 Meso_2591 11 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 110633621 Common - RNA methyltransferase, TrmH family, group 1 Meso_1268 155 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 110635876 Common - Malate/L-lactate dehydrogenase Meso_3548 67 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 110636066 Common - transcriptional regulator, LysR family Meso_3741 120 COG0583 LysR, Transcriptional regulator Transcription 110633766 Common - dihydroneopterin aldolase Meso_1413 68 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 110633556 Nonpathogen - hypothetical protein Meso_1203 1 None None None 110633508 Common - glycosyl transferase, group 1 Meso_1155 169 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110635676 Common - protein tyrosine phosphatase Meso_3348 141 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 110633760 Common - transcriptional regulator, LuxR family Meso_1407 45 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 110632832 Common - Ppx/GppA phosphatase Meso_0471 180 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 110632645 Common motB flagellar motor protein MotB Meso_0284 97 COG1360 MotB, Flagellar motor protein Cell motility and secretion 110634704 Common - xenobiotic compound monooxygenase, DszA family, A subunit Meso_2361 71 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 110634764 Nonpathogen - phosphoesterase, RecJ-like Meso_2423 2 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 110634551 Common - nucleoside diphosphate kinase regulator Meso_2202 82 COG0782 GreA, Transcription elongation factor Transcription 110635935 Common - 3-phosphoshikimate 1-carboxyvinyltransferase Meso_3609 232 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 110635199 Common anmK anhydro-N-acetylmuramic acid kinase Meso_2866 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 110636322 Common - pilus (Caulobacter type) biogenesis lipoprotein CpaD Meso_3998 14 COG5461 COG5461, Type IV pili component Cell motility and secretion 110634955 Common - transcriptional regulator, TetR family Meso_2620 60 COG1309 AcrR, Transcriptional regulator Transcription 110632590 Common - hypothetical protein Meso_0229 5 COG3857 AddB, ATP-dependent nuclease, subunit B DNA replication, recombination, and repair 110636051 Common - amidohydrolase 2 Meso_3726 40 COG3618 COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 110635212 Nonpathogen - hypothetical protein Meso_2879 3 None None None 110635866 Common - HpcH/HpaI aldolase Meso_3538 110 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 110634776 Common - extracellular solute-binding protein, family 1 Meso_2435 61 COG2998 TupB, ABC-type tungstate transport system, permease component Coenzyme metabolism 110635985 Common - phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN Meso_3660 44 COG3709 COG3709, Uncharacterized component of phosphonate metabolism Inorganic ion transport and metabolism 110633847 Nonpathogen - hypothetical protein Meso_1494 1 None None None 110635518 Common - lipid A ABC exporter family, fused ATPase and inner membrane subunits Meso_3189 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 110632560 Nonpathogen - hypothetical protein Meso_0198 1 None None None 110633219 Common - peptidase S9A, prolyl oligopeptidase-like beta-propeller Meso_0862 103 COG1770 PtrB, Protease II Amino acid transport and metabolism 110635956 Common - Rhodanese-like Meso_3630 147 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 110635650 Common - FAD dependent oxidoreductase Meso_3322 125 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 110634899 Common - hypothetical protein Meso_2558 41 COG4111 COG4111, Uncharacterized conserved protein General function prediction only 110634825 Common - Bile acid:sodium symporter Meso_2484 59 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 110635278 Common - acyl-CoA dehydrogenase-like Meso_2949 151 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 110635660 Common - acriflavin resistance protein Meso_3332 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 110636317 Common - Uncharacterised conserved protein UCP030820 Meso_3993 52 COG3749 COG3749, Uncharacterized protein conserved in bacteria Function unknown 110634337 Common - Twin-arginine translocation pathway signal Meso_1987 119 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 110632377 Common - extracellular solute-binding protein, family 3 Meso_0015 132 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 110633293 Common - porin Meso_0939 13 None None None 110633890 Common - short-chain dehydrogenase/reductase SDR Meso_1537 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110633675 Common - Auxin Efflux Carrier Meso_1322 142 COG0679 COG0679, Predicted permeases General function prediction only 110635735 Nonpathogen - protein of unknown function DUF1192 Meso_3407 1 COG5509 COG5509, Uncharacterized small protein containing a coiled-coil domain Function unknown 110633611 Common - protein of unknown function DUF218 Meso_1258 84 COG1434 COG1434, Uncharacterized conserved protein Function unknown 110635098 Common - hypothetical protein Meso_2764 19 None None None 110634133 Common - aminotransferase, class V Meso_1782 230 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 110635906 Common - hypothetical protein Meso_3580 52 COG3893 COG3893, Inactivated superfamily I helicase DNA replication, recombination, and repair 110634928 Common - polysaccharide biosynthesis protein Meso_2587 81 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 110635307 Common - phenylalanine/histidine ammonia-lyase Meso_2978 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 110632818 Common - hypothetical protein Meso_0457 14 COG5482 COG5482, Uncharacterized conserved protein Function unknown 110634580 Common - ATPase, P-type (transporting), HAD superfamily, subfamily IC Meso_2232 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 110634995 Common - hypothetical protein Meso_2661 11 None None None 110635622 Common - major facilitator superfamily MFS_1 Meso_3294 158 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 110633049 Common engA GTP-binding protein EngA Meso_0692 236 COG1160 COG1160, Predicted GTPases General function prediction only 110635250 Common - ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components-like Meso_2921 46 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 110633501 Common - transcriptional regulator, MerR family Meso_1148 92 COG0789 SoxR, Predicted transcriptional regulators Transcription 110632914 Common - CP4-like integrase Meso_0554 92 None None None 110634006 Common - DNA-directed RNA polymerase subunit alpha Meso_1654 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 110635634 Common - cold-shock DNA-binding domain protein Meso_3306 175 COG1278 CspC, Cold shock proteins Transcription 110634170 Common rplL 50S ribosomal protein L7/L12 Meso_1820 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 110636154 Common - hypothetical protein Meso_3830 18 None None None 110635784 Common proA gamma-glutamyl phosphate reductase Meso_3456 188 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 110633054 Common - F0F1 ATP synthase subunit C Meso_0697 20 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 110633800 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Meso_1447 159 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 110635268 Common - acetolactate synthase catalytic subunit Meso_2939 195 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 110632502 Common - polysaccharide deacetylase Meso_0140 43 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 110635752 Common - two component transcriptional regulator, winged helix family Meso_3424 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110633207 Common - short-chain dehydrogenase/reductase SDR Meso_0850 234 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110635912 Common - diguanylate cyclase/phosphodiesterase Meso_3586 175 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 110635385 Common - amidohydrolase Meso_3056 168 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 110633131 Common - hypothetical protein Meso_0774 30 COG4446 COG4446, Uncharacterized protein conserved in bacteria Function unknown 110636012 Common - alpha amylase, catalytic region Meso_3687 164 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 110635529 Common - putative phage tail protein Meso_3200 41 COG4223 COG4223, Uncharacterized protein conserved in bacteria Function unknown 110634821 Common - Endoribonuclease L-PSP Meso_2480 66 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 110633528 Common - sodium/calcium exchanger membrane region Meso_1175 52 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 110634615 Nonpathogen - hypothetical protein Meso_2269 2 None None None 110632874 Common - helix-turn-helix protein, CopG Meso_0514 23 None None None 110635555 Common - LemA Meso_3226 132 COG1704 LemA, Uncharacterized conserved protein Function unknown 110634714 Common - binding-protein-dependent transport systems inner membrane component Meso_2371 206 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 110636003 Common - lipoprotein signal peptidase Meso_3678 196 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 110636261 Common - enoyl-(acyl carrier protein) reductase Meso_3937 232 COG0623 FabI, Enoyl- acyl-carrier-protein 110632800 Common - tetraacyldisaccharide 4'-kinase Meso_0439 130 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 110634655 Common - Rhodanese-like Meso_2310 43 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 110634587 Common - carbamate kinase Meso_2239 65 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 110633604 Nonpathogen - hypothetical protein Meso_1251 1 None None None 110635495 Common - phosphoglucosamine mutase Meso_3166 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 110635468 Common - dihydrodipicolinate synthetase Meso_3139 168 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 110635798 Common gidB glucose-inhibited division protein B Meso_3470 172 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 110635471 Nonpathogen - protein of unknown function DUF1469 Meso_3142 2 None None None 110635791 Common - conserved hypothetical signal peptide protein Meso_3463 7 None None None 110636348 Common - Haloacid dehalogenase-like hydrolase Meso_4024 28 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 110632724 Common - FAD linked oxidase-like Meso_0363 159 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 110635585 Common - pyruvate kinase Meso_3256 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 110634645 Nonpathogen - Activator of Hsp90 ATPase-like Meso_2300 5 COG3832 COG3832, Uncharacterized conserved protein Function unknown 110634608 Common - NUDIX hydrolase Meso_2262 20 COG4119 COG4119, Predicted NTP pyrophosphohydrolase DNA replication, recombination, and repair / General function prediction only 110632494 Common - ABC-2 type transporter Meso_0132 155 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 110634442 Common - transcriptional regulator, ArsR family Meso_2093 31 COG0640 ArsR, Predicted transcriptional regulators Transcription 110632813 Common - formyltetrahydrofolate deformylase Meso_0452 217 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 110632456 Common - dihydroorotate dehydrogenase 2 Meso_0094 234 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 110632740 Common - methionine-R-sulfoxide reductase Meso_0379 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 110633885 Common - hypothetical protein Meso_1532 3 COG3832 COG3832, Uncharacterized conserved protein Function unknown 110636021 Common - glycosyl transferase, group 1 Meso_3696 34 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110636361 Common - nitrogen-fixing NifU-like Meso_4037 96 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 110634041 Common - glutathione S-transferase-like Meso_1689 85 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 110635352 Common - hypothetical protein Meso_3023 33 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 110634358 Common - cell division protein FtsW Meso_2008 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 110634942 Common - SMP-30/Gluconolaconase/LRE-like region Meso_2603 17 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 110634216 Common - FAD dependent oxidoreductase Meso_1866 116 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 110633158 Common - thiamine pyrophosphate enzyme-like TPP-binding Meso_0801 94 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 110633954 Nonpathogen - hypothetical protein Meso_1602 1 None None None 110633090 Common - exodeoxyribonuclease VII small subunit Meso_0733 104 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 110633774 Common - threonine dehydratase Meso_1421 218 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 110633468 Common - polar amino acid ABC transporter, inner membrane subunit Meso_1115 178 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 110635103 Common - Cold-shock protein, DNA-binding Meso_2770 20 None None None 110635687 Common - heme exporter protein CcmB Meso_3359 78 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 110634757 Common - hypothetical protein Meso_2416 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 110633569 Nonpathogen - hypothetical protein Meso_1216 1 None None None 110635069 Common - band 7 protein Meso_2735 216 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 110636254 Common infB translation initiation factor IF-2 Meso_3930 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 110636285 Common - hypothetical protein Meso_3961 31 COG4645 COG4645, Uncharacterized protein conserved in bacteria Function unknown 110633253 Common - cytochrome c-type biogenesis protein CcmF Meso_0899 132 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 110636182 Common - Conjugal transfer protein Meso_3858 34 COG3701 TrbF, Type IV secretory pathway, TrbF components Intracellular trafficking and secretion 110634369 Common - heat shock protein DnaJ-like Meso_2019 51 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 110635177 Common - Creatininase Meso_2844 75 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 110632615 Common - protein of unknown function DUF6, transmembrane Meso_0254 41 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 110634969 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Meso_2635 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 110635451 Common - hypothetical protein Meso_3122 21 COG1470 COG1470, Predicted membrane protein Function unknown 110635323 Common - ErfK/YbiS/YcfS/YnhG Meso_2994 89 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 110635132 Nonpathogen - hypothetical protein Meso_2799 2 None None None 110632410 Common - conserved repeat domain Meso_0048 150 None None None 110632963 Common - hypothetical protein Meso_0606 13 COG4964 CpaC, Flp pilus assembly protein, secretin CpaC Intracellular trafficking and secretion 110634062 Nonpathogen - hypothetical protein Meso_1710 1 None None None 110632447 Common - Peptidoglycan-binding domain 1 Meso_0085 29 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 110636399 Common - GTP-binding protein LepA Meso_4075 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 110635512 Common - Sel1-like repeat Meso_3183 107 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 110633807 Common - DNA repair protein RadC Meso_1454 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 110635241 Common - hypothetical protein Meso_2911 14 None None None 110635398 Common - cobalt chelatase, pCobS small subunit Meso_3069 70 COG0714 COG0714, MoxR-like ATPases General function prediction only 110634278 Common - histidinol dehydrogenase Meso_1928 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 110633494 Common hppA membrane-bound proton-translocating pyrophosphatase Meso_1141 98 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 110633548 Nonpathogen - hypothetical protein Meso_1195 1 None None None 110636221 Common - NmrA-like Meso_3897 127 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 110634725 Common - binding-protein-dependent transport systems inner membrane component Meso_2383 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110632523 Common - glutamine synthetase, catalytic region Meso_0161 225 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 110632595 Common - hypothetical protein Meso_0234 6 None None None 110635427 Common - hypothetical protein Meso_3098 66 COG2388 COG2388, Predicted acetyltransferase General function prediction only 110632419 Common - outer membrane protease Meso_0057 12 COG4571 OmpT, Outer membrane protease Cell envelope biogenesis, outer membrane 110633964 Common - GTP-binding protein, HSR1-related Meso_1612 220 COG2262 HflX, GTPases General function prediction only 110632370 Common - ornithine carbamoyltransferase Meso_0008 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 110635946 Common - Mandelate racemase/muconate lactonizing enzyme-like Meso_3620 108 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 110632386 Common - transcriptional regulator, MerR family Meso_0024 53 COG0789 SoxR, Predicted transcriptional regulators Transcription 110633278 Common - Curlin associated Meso_0924 18 None None None 110632757 Common - alanine racemase Meso_0396 199 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 110632752 Common truA tRNA pseudouridine synthase A Meso_0391 236 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 110634243 Nonpathogen - hypothetical protein Meso_1893 3 None None None 110635113 Common - NAD-dependent epimerase/dehydratase Meso_2780 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 110633372 Common - glycine cleavage system T protein Meso_1018 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 110634234 Common - hypothetical protein Meso_1884 19 COG4477 EzrA, Negative regulator of septation ring formation Cell division and chromosome partitioning 110632532 Common - extracellular solute-binding protein, family 1 Meso_0170 120 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 110635198 Common murQ N-acetylmuramic acid-6-phosphate etherase Meso_2865 90 COG2103 COG2103, Predicted sugar phosphate isomerase General function prediction only 110633910 Common - protein of unknown function DUF971 Meso_1557 52 COG3536 COG3536, Uncharacterized protein conserved in bacteria Function unknown 110634000 Common - pseudouridine synthase, RluA family Meso_1648 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 110636314 Common - hypothetical protein Meso_3990 12 None None None 110636408 Common - extracellular solute-binding protein, family 5 Meso_4084 167 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 110635758 Common - Usg-like Meso_3430 24 COG5425 COG5425, Usg protein, probable subunit of phosphoribosylanthranilate isomerase Amino acid transport and metabolism 110633258 Common - glutamate-ammonia ligase adenylyltransferase Meso_0904 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 110632471 Common - surface presentation of antigens (SPOA) protein Meso_0109 14 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 110635659 Nonpathogen - hypothetical protein Meso_3331 3 None None None 110635022 Common - glycosyl transferase, group 1 Meso_2688 91 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110633562 Nonpathogen - hypothetical protein Meso_1209 1 None None None 110632749 Common - protein of unknown function DUF805 Meso_0388 3 COG3152 COG3152, Predicted membrane protein Function unknown 110632943 Common - outer membrane autotransporter barrel domain Meso_0586 116 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 110634268 Common rplI 50S ribosomal protein L9 Meso_1918 215 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 110636043 Common - transcriptional regulator Meso_3718 19 COG5564 COG5564, Predicted TIM-barrel enzyme, possibly a dioxygenase General function prediction only 110635928 Common - NAD-dependent epimerase/dehydratase Meso_3602 135 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 110632935 Common - transcriptional regulator, AraC family Meso_0577 141 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 110635080 Common - heat shock protein Hsp20 Meso_2746 79 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 110634497 Common - hypothetical protein Meso_2148 34 COG5465 COG5465, Uncharacterized conserved protein Function unknown 110633635 Common - protein of unknown function DUF1476 Meso_1282 27 COG5467 COG5467, Uncharacterized conserved protein Function unknown 110635194 Common - Activator of Hsp90 ATPase-like Meso_2861 13 COG3832 COG3832, Uncharacterized conserved protein Function unknown 110634092 Common - hypothetical protein Meso_1741 5 COG5028 COG5028, Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 Intracellular trafficking and secretion 110635062 Common - YCII-related Meso_2728 35 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 110635041 Common - binding-protein-dependent transport systems inner membrane component Meso_2707 141 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 110635344 Nonpathogen - hypothetical protein Meso_3015 1 None None None 110634427 Common - pseudoazurin Meso_2077 33 COG3794 PetE, Plastocyanin Energy production and conversion 110634739 Common - protein of unknown function DUF112, transmembrane Meso_2397 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 110635725 Common - succinyl-CoA synthetase subunit alpha Meso_3397 213 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 110633928 Nonpathogen - hypothetical protein Meso_1576 1 None None None 110635186 Common - periplasmic solute binding protein Meso_2853 167 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 110632697 Common - Siderophore-interacting protein Meso_0336 63 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 110633141 Common - short-chain dehydrogenase/reductase SDR Meso_0784 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110634251 Nonpathogen - hypothetical protein Meso_1901 1 None None None 110632882 Common - Cobyrinic acid a,c-diamide synthase Meso_0522 197 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 110634326 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Meso_1976 203 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 110633095 Nonpathogen - putative aminotransferase Meso_0738 2 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 110635079 Common - aromatic amino acid beta-eliminating lyase/threonine aldolase Meso_2745 101 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 110636095 Common - SMP-30/Gluconolaconase/LRE-like region Meso_3770 74 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 110632954 Common - MCP methyltransferase, CheR-type Meso_0597 149 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 110635704 Common - helicase-like Meso_3376 63 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 110632731 Common - metallophosphoesterase Meso_0370 87 COG1409 Icc, Predicted phosphohydrolases General function prediction only 110635089 Common - Capsule polysaccharide biosynthesis Meso_2755 30 COG3563 KpsC, Capsule polysaccharide export protein Cell envelope biogenesis, outer membrane 110635401 Common - hypothetical protein Meso_3072 18 COG4246 COG4246, Uncharacterized protein conserved in bacteria Function unknown 110632518 Nonpathogen - NoeA host specific nodulation protein Meso_0156 6 None None None 110632485 Nonpathogen - hypothetical protein Meso_0123 1 None None None 110634546 Common - DGPFAETKE domain containing protein Meso_2197 46 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 110632483 Nonpathogen - hypothetical protein Meso_0121 1 None None None 110636093 Common - ABC transporter related Meso_3768 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 110633517 Common rplM 50S ribosomal protein L13 Meso_1164 233 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 110633686 Common - phosphate transporter Meso_1333 148 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 110633618 Common - Indigoidine synthase A like protein Meso_1265 49 COG2313 IndA, Uncharacterized enzyme involved in pigment biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 110633198 Common - protein of unknown function DUF1238 Meso_0841 14 COG3802 GguC, Uncharacterized protein conserved in bacteria Function unknown 110636290 Common - protein of unknown function DUF112, transmembrane Meso_3966 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 110634569 Common fixK transcriptional regulator FixK Meso_2220 114 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 110634871 Common - binding-protein-dependent transport systems inner membrane component Meso_2530 164 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 110634148 Common - preprotein translocase, YajC subunit Meso_1797 26 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 110633738 Common - undecaprenyl diphosphate synthase Meso_1385 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 110635229 Common - hypothetical protein Meso_2898 2 None None None 110635824 Common - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase Meso_3496 215 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 110635236 Common - Poly(3-hydroxybutyrate) depolymerase-like Meso_2906 35 COG3509 LpqC, Poly(3-hydroxybutyrate) depolymerase Secondary metabolites biosynthesis, transport, and catabolism 110634394 Common - ABC transporter related Meso_2044 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 110634289 Common - thioesterase superfamily Meso_1939 36 COG0824 FcbC, Predicted thioesterase General function prediction only 161621419 Common - S-adenosylmethionine synthetase Meso_3924 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 110636416 Common - lytic murein transglycosylase Meso_4092 105 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 110635811 Common - preprotein translocase subunit SecB Meso_3483 107 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 110632610 Nonpathogen - hypothetical protein Meso_0249 1 None None None 110634104 Common - hypothetical protein Meso_1753 32 COG3911 COG3911, Predicted ATPase General function prediction only 110636335 Common - Protein of unknown function UPF0011 Meso_4011 208 COG0313 COG0313, Predicted methyltransferases General function prediction only 110636056 Common - Hydantoinase/oxoprolinase Meso_3731 116 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110632698 Common - major facilitator superfamily MFS_1 Meso_0337 18 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 110634950 Common - hypothetical protein Meso_2612 19 None None None 110633038 Common - Ribosomal RNA adenine methylase transferase Meso_0681 38 COG3963 COG3963, Phospholipid N-methyltransferase Lipid metabolism 110636356 Common - Methyltransferase type 11 Meso_4032 17 COG5459 COG5459, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 110635217 Common - asparagine synthase (glutamine-hydrolyzing) Meso_2884 188 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 110635802 Common rho transcription termination factor Rho Meso_3474 213 COG1158 Rho, Transcription termination factor Transcription 110632617 Common - hypothetical protein Meso_0256 71 COG2718 COG2718, Uncharacterized conserved protein Function unknown 110636396 Common - Rubrerythrin Meso_4072 24 COG1633 COG1633, Uncharacterized conserved protein Function unknown 110634050 Common - Invasion associated locus B Meso_1698 17 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 110632537 Common - transcriptional regulator, RpiR family Meso_0175 50 COG1737 RpiR, Transcriptional regulators Transcription 110633553 Common - DNA methylase N-4/N-6 Meso_1200 43 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 110633997 Common gltX glutamyl-tRNA synthetase Meso_1645 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 110634046 Common - Alcohol dehydrogenase, zinc-binding Meso_1694 175 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 110632679 Common - putative ribonuclease BN Meso_0318 109 COG1295 Rbn, Predicted membrane protein Function unknown 110636164 Common - hypothetical protein Meso_3840 27 COG5606 COG5606, Uncharacterized conserved small protein Function unknown 110634974 Common - allantoate amidohydrolase Meso_2640 85 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 110634482 Nonpathogen - hypothetical protein Meso_2133 1 None None None 110634638 Common - NIPSNAP domain containing protein Meso_2293 13 None None None 110632971 Common - type II and III secretion system protein Meso_0614 140 COG4964 CpaC, Flp pilus assembly protein, secretin CpaC Intracellular trafficking and secretion 110635696 Common - band 7 protein Meso_3368 199 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 110632785 Common - bifunctional riboflavin kinase/FMN adenylyltransferase Meso_0424 211 COG0196 RibF, FAD synthase Coenzyme metabolism 110635723 Common - malate dehydrogenase Meso_3395 187 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 110635292 Common - ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components-like Meso_2963 20 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 110633873 Common - protein of unknown function DUF490 Meso_1520 89 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 110635057 Common - protein of unknown function DUF533 Meso_2723 38 COG2979 COG2979, Uncharacterized protein conserved in bacteria Function unknown 110634869 Common - NIPSNAP domain containing protein Meso_2528 17 None None None 110632586 Common - hypothetical protein Meso_0225 5 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 110634335 Common - FAD linked oxidase-like Meso_1985 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 110634812 Nonpathogen - hypothetical protein Meso_2471 1 None None None 110633823 Common - hypothetical protein Meso_1470 15 COG5453 COG5453, Uncharacterized conserved protein Function unknown 110632639 Common flgK flagellar hook-associated protein FlgK Meso_0278 108 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 110635831 Common - luciferase-like Meso_3503 111 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 110632987 Common - Activator of Hsp90 ATPase-like Meso_0630 19 COG3832 COG3832, Uncharacterized conserved protein Function unknown 110633335 Common - short-chain dehydrogenase/reductase SDR Meso_0981 231 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110635497 Common - tRNA(Ile)-lysidine synthetase Meso_3168 100 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 110633838 Common - cyclic nucleotide-binding protein Meso_1485 68 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 110633365 Common - nitroreductase Meso_1011 80 COG0778 NfnB, Nitroreductase Energy production and conversion 110635485 Common - RNA polymerase factor sigma-32 Meso_3156 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 110634031 Common rpsJ 30S ribosomal protein S10 Meso_1679 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 110632705 Common - TRAP C4-dicarboxylate transport system permease DctM subunit Meso_0344 122 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 110632407 Nonpathogen - hypothetical protein Meso_0045 1 None None None 110633286 Nonpathogen - hypothetical protein Meso_0932 4 None None None 110634727 Common - flavin reductase-like, FMN-binding Meso_2385 121 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 110634711 Common - chaperonin Cpn60/TCP-1 Meso_2368 217 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 110633750 Common - single-strand binding protein Meso_1397 207 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 110633428 Common - Mandelate racemase/muconate lactonizing enzyme-like Meso_1074 99 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 110632669 Common - hypothetical protein Meso_0308 8 None None None 110633899 Common - carbohydrate kinase, YjeF related protein Meso_1546 215 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 110634059 Common - peptide chain release factor 2 Meso_1707 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 110632504 Common - oxidoreductase-like Meso_0142 179 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 110632991 Common - peptidase S11, D-alanyl-D-alanine carboxypeptidase 1 Meso_0634 153 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 110634631 Common - protein of unknown function DUF302 Meso_2285 42 COG3439 COG3439, Uncharacterized conserved protein Function unknown 110633295 Common - dihydrodipicolinate synthase Meso_0941 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 110635774 Common - MgtC/SapB transporter Meso_3446 92 COG1285 SapB, Uncharacterized membrane protein Function unknown 110634990 Common - Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation)-like Meso_2656 50 COG2843 PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) Cell envelope biogenesis, outer membrane 110635961 Common - extracellular solute-binding protein, family 5 Meso_3635 195 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 110632672 Common - isocitrate lyase Meso_0311 128 COG2224 AceA, Isocitrate lyase Energy production and conversion 110634418 Nonpathogen - hypothetical protein Meso_2068 1 None None None 110633475 Common aspS aspartyl-tRNA synthetase Meso_1122 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110633274 Common - protein of unknown function DUF922 Meso_0920 7 COG5664 COG5664, Predicted secreted Zn-dependent protease Posttranslational modification, protein turnover, chaperones 110634883 Common - binding-protein-dependent transport systems inner membrane component Meso_2542 180 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 110633564 Nonpathogen - hypothetical protein Meso_1211 3 COG2411 COG2411, Uncharacterized conserved protein Function unknown 110632630 Common - hypothetical protein Meso_0269 13 COG3951 COG3951, Rod binding protein Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 110633816 Common nadE NAD synthetase Meso_1463 238 COG0171 NadE, NAD synthase Coenzyme metabolism 110635838 Common - conserved hypothetical membrane-anchored protein Meso_3510 68 COG2323 COG2323, Predicted membrane protein Function unknown 110633115 Common - GCN5-related N-acetyltransferase Meso_0758 137 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 110633840 Common - hypothetical protein Meso_1487 3 None None None 110635929 Common gyrB DNA gyrase subunit B Meso_3603 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 110635253 Common - acetolactate synthase catalytic subunit Meso_2924 216 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 110635515 Common - NAD-dependent epimerase/dehydratase Meso_3186 130 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 110632399 Common - binding-protein-dependent transport systems inner membrane component Meso_0037 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110633030 Common - ribosomal protein L35 Meso_0673 113 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 110634072 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B Meso_1720 212 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 110635762 Common - short-chain dehydrogenase/reductase SDR Meso_3434 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110634844 Common - HpcH/HpaI aldolase Meso_2503 74 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 110634815 Common - cytochrome c oxidase, subunit II Meso_2474 142 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 110634276 Common - Peptidase M15A Meso_1926 53 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 110634472 Common - NADPH-dependent FMN reductase Meso_2123 70 COG0431 COG0431, Predicted flavoprotein General function prediction only 110634745 Common - purine phosphorylase, family 2 Meso_2403 166 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 110636379 Common - bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase Meso_4055 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 110634855 Common - transcriptional regulator, GntR family Meso_2514 139 COG1802 GntR, Transcriptional regulators Transcription 110633990 Common trpD anthranilate phosphoribosyltransferase Meso_1638 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 110635510 Common - protein of unknown function DUF81 Meso_3181 65 COG0730 COG0730, Predicted permeases General function prediction only 110633100 Common - protoheme IX farnesyltransferase Meso_0743 167 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 110633360 Common - hypothetical protein Meso_1006 179 COG0759 COG0759, Uncharacterized conserved protein Function unknown 110635856 Common - Erythromycin esterase Meso_3528 35 COG2312 COG2312, Erythromycin esterase homolog General function prediction only 110633457 Nonpathogen - hypothetical protein Meso_1103 1 None None None 110634960 Common - binding-protein-dependent transport systems inner membrane component Meso_2626 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110636283 Common - SH3, type 3 Meso_3959 15 COG4991 COG4991, Uncharacterized protein with a bacterial SH3 domain homologue Function unknown 110635436 Common - RNA polymerase sigma factor Meso_3107 169 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 110634181 Common - putative nitrilotriacetate monooxygenase component A Meso_1831 50 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 110633399 Common lipB lipoyltransferase Meso_1045 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 110632660 Common - hypothetical protein Meso_0299 6 None None None 110633989 Common - peptidyl-prolyl cis-trans isomerse D Meso_1637 128 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 110635629 Common - hypothetical protein Meso_3301 66 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 110635322 Common - peptidase M23B Meso_2993 189 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 110634420 Common - hypothetical protein Meso_2070 75 COG2983 COG2983, Uncharacterized conserved protein Function unknown 110632768 Common - beta-lactamase Meso_0407 14 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 110635610 Common - regulatory protein GntR, HTH Meso_3282 136 COG2186 FadR, Transcriptional regulators Transcription 110634457 Common - amidinotransferase Meso_2108 23 COG1834 COG1834, N-Dimethylarginine dimethylaminohydrolase Amino acid transport and metabolism 110633009 Common - polysaccharide export protein Meso_0652 36 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 110635980 Common - cytidine deaminase Meso_3655 109 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 110633849 Common - ketol-acid reductoisomerase Meso_1496 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 110635073 Common - UTP-glucose-1-phosphate uridylyltransferase Meso_2739 233 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 110634131 Common - FeS assembly ATPase SufC Meso_1780 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 110633982 Common - dehydrogenase, E1 component Meso_1630 160 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 110636307 Common - hypothetical protein Meso_3983 136 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 110634858 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Meso_2517 34 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 110633677 Common - transcriptional regulator, AsnC family Meso_1324 155 COG1522 Lrp, Transcriptional regulators Transcription 110636376 Common - 6-pyruvoyl tetrahydropterin synthase and hypothetical protein Meso_4052 117 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 110634897 Common - L-aspartate oxidase Meso_2556 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 110636230 Common - putative phospholipid N-methyltransferase Meso_3906 25 COG3963 COG3963, Phospholipid N-methyltransferase Lipid metabolism 110634786 Nonpathogen - molybdopterin-guanine dinucleotide biosynthesis protein A Meso_2445 8 None None None 110632925 Common - aldehyde dehydrogenase Meso_0566 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 110632989 Common - FAD dependent oxidoreductase Meso_0632 37 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 110634571 Common fixJ response regulator FixJ Meso_2222 221 COG4566 TtrR, Response regulator Signal transduction mechanisms 110633042 Common - polyhydroxyalkanoate depolymerase, intracellular Meso_0685 44 COG4553 DepA, Poly-beta-hydroxyalkanoate depolymerase Lipid metabolism 110633089 Common - histone deacetylase superfamily Meso_0732 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 110632425 Common - ABC transporter related Meso_0063 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 110632602 Nonpathogen - hypothetical protein Meso_0241 2 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 110633084 Common - enoyl-(acyl carrier protein) reductase Meso_0727 236 COG0623 FabI, Enoyl- acyl-carrier-protein 110634553 Common - formate-tetrahydrofolate ligase, FTHFS Meso_2204 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 110633370 Common - glycine dehydrogenase Meso_1016 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 110632554 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Meso_0192 215 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 110634306 Common - Mandelate racemase/muconate lactonizing enzyme-like Meso_1956 106 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 110634317 Common - phosphoribosylglycinamide formyltransferase Meso_1967 219 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 110634903 Common - glycine oxidase ThiO Meso_2562 108 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 110632544 Common - exodeoxyribonuclease VII, large subunit Meso_0182 198 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 110633347 Common - hypothetical protein Meso_0993 6 None None None 110633443 Common - transcriptional regulator, MarR family Meso_1089 64 COG1846 MarR, Transcriptional regulators Transcription 110634696 Nonpathogen - hypothetical protein Meso_2352 1 None None None 110633946 Common - binding-protein-dependent transport systems inner membrane component Meso_1594 148 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 110633696 Common - hypothetical protein Meso_1343 20 COG4655 COG4655, Predicted membrane protein Function unknown 110635140 Common - hypothetical protein Meso_2807 7 None None None 110635010 Common - glycogen debranching enzyme GlgX Meso_2676 166 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 110632863 Common - TrbL/VirB6 plasmid conjugal transfer protein Meso_0503 24 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 110632640 Common flgE flagellar hook protein FlgE Meso_0279 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 110636194 Common - Isoprenylcysteine carboxyl methyltransferase Meso_3870 37 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 110632801 Common - hypothetical protein Meso_0440 23 COG3908 COG3908, Uncharacterized protein conserved in bacteria Function unknown 110634527 Common - protein of unknown function DUF1285 Meso_2178 44 COG3816 COG3816, Uncharacterized protein conserved in bacteria Function unknown 110635416 Common - ChaC-like protein Meso_3087 44 COG3703 ChaC, Uncharacterized protein involved in cation transport Inorganic ion transport and metabolism 110635310 Common - ABC transporter related Meso_2981 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 110636184 Common - conjugation TrbI-like protein Meso_3860 56 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 110635887 Common - ROK domain containing protein Meso_3560 102 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 110632398 Common - binding-protein-dependent transport systems inner membrane component Meso_0036 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110632365 Common recF recombination protein F Meso_0003 165 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 110635125 Common - cytochrome c oxidase, subunit II Meso_2792 157 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 110633414 Nonpathogen - Glyoxalase/bleomycin resistance protein/dioxygenase Meso_1060 3 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 110634022 Common - 50S ribosomal protein L29 Meso_1670 176 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 110634917 Common - polysaccharide pyruvyl transferase Meso_2576 11 COG2327 WcaK, Uncharacterized conserved protein Function unknown 110635587 Common - ribosomal protein L36 Meso_3258 72 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 110635563 Common - outer membrane lipoprotein carrier protein LolA Meso_3234 40 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 110635019 Common - UreE urease accessory-like Meso_2685 67 COG2371 UreE, Urease accessory protein UreE Posttranslational modification, protein turnover, chaperones 110632852 Common - glycosyl transferase, group 1 Meso_0492 34 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110633450 Common - binding-protein-dependent transport systems inner membrane component Meso_1096 164 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 110633248 Common - two component transcriptional regulator, winged helix family Meso_0894 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110636001 Common - conserved hypothetical protein 95 Meso_3676 115 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 110636237 Nonpathogen - hypothetical protein Meso_3913 1 None None None 110635220 Common - fumarylacetoacetate (FAA) hydrolase Meso_2887 73 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 110635737 Common - protein of unknown function DUF465 Meso_3409 17 COG5570 COG5570, Uncharacterized small protein Function unknown 110635376 Common - Uncharacterized protein UPF0065 Meso_3047 67 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 110635574 Common - succinate dehydrogenase, cytochrome b subunit Meso_3245 40 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 110634304 Common - ABC transporter related Meso_1954 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 110633708 Nonpathogen - hypothetical protein Meso_1355 1 None None None 110633328 Common - transcriptional regulator, ArsR family Meso_0974 73 COG0640 ArsR, Predicted transcriptional regulators Transcription 110635860 Common - outer membrane autotransporter barrel domain Meso_3532 42 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 110634226 Common - manganese containing catalase Meso_1876 46 COG3546 COG3546, Mn-containing catalase Inorganic ion transport and metabolism 110636203 Common - beta-lactamase-like Meso_3879 132 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 110636271 Common - ferric uptake regulator, Fur family Meso_3947 196 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 110633743 Common fabZ (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase Meso_1390 186 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 110636070 Common - binding-protein-dependent transport systems inner membrane component Meso_3745 216 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 110633105 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase Meso_0748 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 110635717 Common - signal recognition particle-docking protein FtsY Meso_3389 246 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 110636263 Common - 3-hydroxydecanoyl-(acyl carrier protein) dehydratase Meso_3939 82 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 110635553 Common - pyridoxamine kinase Meso_3224 136 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 110635341 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein Meso_3012 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 110633755 Common coaD phosphopantetheine adenylyltransferase Meso_1402 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 110635185 Common - ABC transporter related Meso_2852 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 110633395 Common - lipoprotein releasing system, transmembrane protein, LolC/E family Meso_1041 218 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 110635775 Nonpathogen - hypothetical protein Meso_3447 1 None None None 110633027 Common - hypothetical protein Meso_0670 38 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 110633430 Common - Hydratase/decarboxylase Meso_1076 64 COG3971 COG3971, 2-keto-4-pentenoate hydratase Secondary metabolites biosynthesis, transport, and catabolism 110633905 Common - Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase Meso_1552 54 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 110633225 Common - putative monovalent cation/H+ antiporter subunit E Meso_0868 96 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 110634084 Common - cold-shock DNA-binding domain protein Meso_1733 149 COG1278 CspC, Cold shock proteins Transcription 110633795 Common - periplasmic binding protein Meso_1442 144 COG4558 ChuT, ABC-type hemin transport system, periplasmic component Inorganic ion transport and metabolism 110634158 Common - ABC transporter related Meso_1807 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 110636204 Common - thymidine phosphorylase Meso_3880 123 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 110636175 Common - type II secretion system protein E Meso_3851 221 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 110635245 Common - hypothetical protein Meso_2915 13 None None None 110634668 Common - Conjugal transfer protein TrbC Meso_2323 22 COG3838 VirB2, Type IV secretory pathway, VirB2 components (pilins) Intracellular trafficking and secretion 110636009 Common - cyclase/dehydrase Meso_3684 32 COG5637 COG5637, Predicted integral membrane protein Function unknown 110633020 Common - acetyl-CoA carboxylase subunit beta Meso_0663 218 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 110636034 Nonpathogen - hypothetical protein Meso_3709 4 None None None 110635448 Common - phosphate ABC transporter, inner membrane subunit PstA Meso_3119 222 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 110633488 Common - hypothetical protein Meso_1135 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 110633701 Common pleD response regulator PleD Meso_1348 224 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 110635987 Common - protein of unknown function DUF1045 Meso_3662 27 None None None 110632795 Common - peptidase U62, modulator of DNA gyrase Meso_0434 158 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 110635903 Common - PAS/PAC sensor signal transduction histidine kinase Meso_3577 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110636244 Common - PhoH-like protein Meso_3920 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 110633382 Common - NADH dehydrogenase subunit G Meso_1028 190 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 110633405 Common - hypothetical protein Meso_1051 27 COG4032 COG4032, Predicted thiamine-pyrophosphate-binding protein General function prediction only 110632982 Common - GCN5-related N-acetyltransferase Meso_0625 29 COG0456 RimI, Acetyltransferases General function prediction only 110635551 Common - drug resistance transporter, Bcr/CflA subfamily Meso_3222 146 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 110635003 Common - ABC transporter related Meso_2669 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 110636347 Common - aldo/keto reductase Meso_4023 167 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 110635035 Common - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase Meso_2701 140 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 110636159 Common - hypothetical protein Meso_3835 13 None None None 110635090 Common - Capsule polysaccharide export protein-like Meso_2756 41 COG3524 KpsE, Capsule polysaccharide export protein Cell envelope biogenesis, outer membrane 110635593 Common - hypothetical protein Meso_3264 70 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 110635607 Common - acyl-CoA dehydrogenase-like Meso_3279 63 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 110636116 Nonpathogen - hypothetical protein Meso_3791 4 None None None 110633506 Common - hypothetical protein Meso_1153 13 None None None 110633858 Common - binding-protein-dependent transport systems inner membrane component Meso_1505 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110634597 Common - cytochrome c oxidase, cbb3-type, subunit I Meso_2250 143 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 110632458 Common - outer membrane protein, 31 kDa Meso_0096 25 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 110633059 Common - NnrU Meso_0702 27 COG4094 COG4094, Predicted membrane protein Function unknown 110633788 Common - TonB family protein Meso_1435 84 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 110635330 Common - aspartate kinase Meso_3001 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 110632375 Common - protein of unknown function DUF344 Meso_0013 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 110634823 Common - transcriptional regulator, LysR family Meso_2482 106 COG0583 LysR, Transcriptional regulator Transcription 110634716 Common - aminotransferase, class V Meso_2373 239 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 110633590 Common - hypothetical protein Meso_1237 4 None None None 110634323 Common - OmpA-like transmembrane region Meso_1973 18 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 110633726 Common - ATP-dependent Clp protease, ATP-binding subunit clpA Meso_1373 225 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 110635261 Common - Uncharacterized protein UPF0065 Meso_2932 69 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 110635744 Nonpathogen - protein of unknown function DUF1674 Meso_3416 3 COG5508 COG5508, Uncharacterized conserved small protein Function unknown 110634122 Common - cytochrome c biogenesis protein, transmembrane region Meso_1771 115 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 110635115 Common - UDP-glucose/GDP-mannose dehydrogenase Meso_2782 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 110636319 Nonpathogen - hypothetical protein Meso_3995 1 None None None 110635620 Common - MaoC-like dehydratase Meso_3292 82 COG2030 MaoC, Acyl dehydratase Lipid metabolism 110634280 Common - Endoribonuclease L-PSP Meso_1930 76 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 110634682 Common - hypothetical protein Meso_2338 25 None None None 110634679 Common - hypothetical protein Meso_2334 22 None None None 110634060 Common - penicillin-binding protein, 1A family Meso_1708 203 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 110634172 Common rplA 50S ribosomal protein L1 Meso_1822 242 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 110633075 Common ubiA prenyltransferase Meso_0718 171 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 110632772 Common - short-chain dehydrogenase/reductase SDR Meso_0411 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110635306 Common - Substrate-binding region of ABC-type glycine betaine transport system Meso_2977 90 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 110634287 Common - binding-protein-dependent transport systems inner membrane component Meso_1937 212 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 110634389 Nonpathogen - hypothetical protein Meso_2039 4 None None None 110632727 Common - GntR-like Meso_0366 126 COG2186 FadR, Transcriptional regulators Transcription 110636324 Common - type II secretion system protein E Meso_4000 162 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 110632792 Common - peptidase M16-like Meso_0431 170 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 110635365 Common fadE acyl-CoA dehydrogenase Meso_3036 143 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 110634502 Common - peptidase M24 Meso_2153 47 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 110632816 Common - Myo-inositol catabolism IolB region Meso_0455 54 COG3718 IolB, Uncharacterized enzyme involved in inositol metabolism Carbohydrate transport and metabolism 110634019 Common rplX 50S ribosomal protein L24 Meso_1667 213 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 110635531 Common hemC porphobilinogen deaminase Meso_3202 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 110635910 Common - hypothetical protein Meso_3584 21 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 110633854 Common - transcriptional regulator, AraC family Meso_1501 145 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 110635919 Common - ABC transporter related Meso_3593 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 110636141 Common - hypothetical protein Meso_3817 6 None None None 110632827 Common - MIP family channel proteins Meso_0466 136 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 110634800 Common - FAD linked oxidase-like Meso_2459 99 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 110633306 Common recO DNA repair protein RecO Meso_0952 41 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 110632474 Common - type III secretion protein SpaR/YscT/HrcT Meso_0112 92 COG4791 EscT, Type III secretory pathway, component EscT Intracellular trafficking and secretion 110636050 Common - HpcH/HpaI aldolase Meso_3725 74 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 110633359 Common - hypothetical protein Meso_1005 64 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 110633424 Nonpathogen - hypothetical protein Meso_1070 2 COG4994 COG4994, Uncharacterized protein conserved in bacteria Function unknown 110635414 Common - cyclohexadienyl dehydrogenase Meso_3085 156 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 110634997 Common - transcriptional regulator, LysR family Meso_2663 182 COG0583 LysR, Transcriptional regulator Transcription 110634573 Common - short-chain dehydrogenase/reductase SDR Meso_2224 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110634656 Common - transcriptional regulator, LuxR family Meso_2311 54 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 110634613 Common - Transketolase-like Meso_2267 209 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 110633731 Common - glycerophosphoryl diester phosphodiesterase Meso_1378 136 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 110633602 Nonpathogen - hypothetical protein Meso_1249 1 None None None 110632500 Common - 3-demethylubiquinone-9 3-methyltransferase Meso_0138 64 COG3865 COG3865, Uncharacterized protein conserved in bacteria Function unknown 110634804 Common - transcriptional regulator, MarR family Meso_2463 76 COG1846 MarR, Transcriptional regulators Transcription 110633537 Nonpathogen - hypothetical protein Meso_1184 1 None None None 110633938 Common - malonyl-CoA synthase Meso_1586 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110633711 Common - dihydroorotase Meso_1358 210 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 110634593 Common - transcriptional regulator, Crp/Fnr family Meso_2246 166 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 110634509 Common - MaoC-like dehydratase Meso_2160 63 COG2030 MaoC, Acyl dehydratase Lipid metabolism 110633291 Nonpathogen - hypothetical protein Meso_0937 1 None None None 110633052 Common - hypothetical protein Meso_0695 29 COG5336 COG5336, Uncharacterized protein conserved in bacteria Function unknown 110632714 Common - hypothetical protein Meso_0353 55 COG0398 COG0398, Uncharacterized conserved protein Function unknown 110635085 Common - glycosyl transferase, group 2 family protein Meso_2751 15 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 110634835 Common - aldehyde dehydrogenase Meso_2494 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 110634195 Nonpathogen - hypothetical protein Meso_1845 1 None None None 110634012 Common rpmD 50S ribosomal protein L30 Meso_1660 100 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 110635200 Common - protein of unknown function DUF534 Meso_2867 57 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 110635382 Common - transcriptional regulator, LysR family Meso_3053 155 COG0583 LysR, Transcriptional regulator Transcription 110634830 Common - TRAP dicarboxylate transporter- DctP subunit Meso_2489 96 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 110633643 Common - ATPase associated with various cellular activities, AAA_5 Meso_1290 103 COG0714 COG0714, MoxR-like ATPases General function prediction only 110634923 Common - hypothetical protein Meso_2582 16 None None None 110633352 Common - binding-protein-dependent transport systems inner membrane component Meso_0998 220 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110635647 Common - methylmalonate-semialdehyde dehydrogenase Meso_3319 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 110635548 Common atpC F0F1 ATP synthase subunit epsilon Meso_3219 176 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 110633588 Common - hypothetical protein Meso_1235 4 None None None 110634945 Common - Pyrrolo-quinoline quinone Meso_2606 42 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 110635810 Common - DNA polymerase III subunit epsilon Meso_3482 200 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 110635461 Common - binding-protein-dependent transport systems inner membrane component Meso_3132 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110632647 Common fliF flagellar MS-ring protein Meso_0286 129 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 110634098 Common - hypothetical protein Meso_1747 13 COG3242 COG3242, Uncharacterized protein conserved in bacteria Function unknown 110633631 Common - hypothetical protein Meso_1278 6 None None None 110632454 Common - hypothetical protein Meso_0092 5 None None None 110633377 Common - NADH dehydrogenase subunit B Meso_1023 191 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 110634449 Common - ABC-2 type transporter Meso_2100 79 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 110633312 Common - metal dependent phosphohydrolase Meso_0958 30 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 110635155 Common - transcriptional regulator, IclR family Meso_2822 113 COG1414 IclR, Transcriptional regulator Transcription 110634490 Common - transcriptional regulator, MarR family Meso_2141 39 COG1846 MarR, Transcriptional regulators Transcription 110635990 Common - PTS IIA-like nitrogen-regulatory protein PtsN Meso_3665 131 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 110633012 Nonpathogen - hypothetical protein Meso_0655 1 None None None 110635662 Common - transcriptional regulator, TetR family Meso_3334 54 COG1309 AcrR, Transcriptional regulator Transcription 110636256 Common truB tRNA pseudouridine synthase B Meso_3932 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 110635669 Common - signal recognition particle protein Meso_3341 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 110636155 Common - hypothetical protein Meso_3831 3 None None None 110632961 Common - type II secretion system protein E Meso_0604 160 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 110634088 Nonpathogen - hypothetical protein Meso_1737 5 None None None 110633776 Common - DEAD/DEAH box helicase-like Meso_1423 245 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 110635648 Nonpathogen - conserved hypothetical signal peptide protein Meso_3320 7 None None None 110635734 Common - Alcohol dehydrogenase, zinc-binding Meso_3406 203 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 110634934 Common - polysaccharide export protein Meso_2593 44 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 110633623 Common rpsD 30S ribosomal protein S4 Meso_1270 230 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 110632891 Nonpathogen - hypothetical protein Meso_0531 5 None None None 110634743 Common - FMN-dependent alpha-hydroxy acid dehydrogenase Meso_2401 112 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 110632466 Common - type III secretion apparatus lipoprotein, YscJ/HrcJ family Meso_0104 31 COG4669 EscJ, Type III secretory pathway, lipoprotein EscJ Intracellular trafficking and secretion 110635043 Common - oxidoreductase-like Meso_2709 173 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 110636148 Nonpathogen - hypothetical protein Meso_3824 2 None None None 110635579 Nonpathogen - hypothetical protein Meso_3250 6 None None None 110632606 Nonpathogen - hypothetical protein Meso_0245 1 None None None 110632848 Common - UDP-glucose/GDP-mannose dehydrogenase Meso_0487 202 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 110635653 Common - ABC transporter related Meso_3325 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 110632937 Common - hypothetical protein Meso_0579 6 COG2706 COG2706, 3-carboxymuconate cyclase Carbohydrate transport and metabolism 110632582 Nonpathogen - hypothetical protein Meso_0221 1 None None None 110634774 Common - molybdenum cofactor synthesis domain Meso_2433 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 110633762 Nonpathogen - hypothetical protein Meso_1409 1 COG2198 ArcB, FOG: HPt domain Signal transduction mechanisms 110634310 Common - short-chain dehydrogenase/reductase SDR Meso_1960 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 110635383 Common - transcriptional regulator, LuxR family Meso_3054 34 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 110634118 Common acpP acyl carrier protein Meso_1767 209 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110634111 Common - putative survival protein surA precursor (peptidyl-prolyl cis-trans isomerase SurA) Meso_1760 81 None None None 110634520 Common - tRNA/rRNA methyltransferase (SpoU) Meso_2171 160 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 110635234 Common - TRAP dicarboxylate transporter- DctP subunit Meso_2904 30 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 110635950 Common - TRAP transporter, 4TM/12TM fusion protein Meso_3624 125 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 110633185 Common - hypothetical protein Meso_0828 2 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 110634516 Nonpathogen - hypothetical protein Meso_2167 4 None None None 110635763 Common - hypothetical protein Meso_3435 5 None None None 110633665 Common - binding-protein-dependent transport systems inner membrane component Meso_1312 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110636274 Nonpathogen - hypothetical protein Meso_3950 1 None None None 110633237 Common - hypothetical protein Meso_0880 8 COG5330 COG5330, Uncharacterized protein conserved in bacteria Function unknown 110636370 Common - hypothetical protein Meso_4046 33 COG4134 COG4134, ABC-type uncharacterized transport system, periplasmic component General function prediction only 110635561 Common - hypothetical protein Meso_3232 38 COG1872 COG1872, Uncharacterized conserved protein Function unknown 110633651 Common - MATE efflux family protein Meso_1298 144 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 110633638 Common - adenylosuccinate lyase Meso_1285 239 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 110635007 Common - malto-oligosyltrehalose synthase Meso_2673 134 COG3280 TreY, Maltooligosyl trehalose synthase Carbohydrate transport and metabolism 110633578 Common - hypothetical protein Meso_1225 2 None None None 110632589 Nonpathogen - hypothetical protein Meso_0228 1 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 110634241 Nonpathogen - hypothetical protein Meso_1891 3 None None None 110634557 Common - tRNA/rRNA methyltransferase (SpoU) Meso_2208 141 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 110635537 Common - Protein of unknown function UPF0001 Meso_3208 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 110636278 Common - Tetratricopeptide TPR_2 Meso_3954 32 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 110635619 Common - acyl-CoA dehydrogenase-like Meso_3291 167 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 110635214 Common nadE NAD synthetase Meso_2881 200 COG0171 NadE, NAD synthase Coenzyme metabolism 110634549 Common - phosphoesterase, PA-phosphatase related Meso_2200 62 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 110634689 Common - hypothetical protein Meso_2345 34 None None None 110634564 Common - beta-lactamase Meso_2215 61 COG2367 PenP, Beta-lactamase class A Defense mechanisms 110633140 Common - Xylose isomerase-like TIM barrel Meso_0783 21 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 110633060 Common rnhB ribonuclease HII Meso_0703 207 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 110635572 Common sdhB succinate dehydrogenase iron-sulfur subunit Meso_3243 193 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 110634232 Common - hypothetical protein Meso_1882 3 None None None 110635868 Common - binding-protein-dependent transport systems inner membrane component Meso_3540 181 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 110635756 Common mtgA monofunctional biosynthetic peptidoglycan transglycosylase Meso_3428 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 110636080 Common - flavin reductase-like, FMN-binding Meso_3755 100 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 110632898 Common - parB-like partition proteins Meso_0538 150 COG1475 Spo0J, Predicted transcriptional regulators Transcription 110633860 Common - ROK domain containing protein Meso_1507 172 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 110635196 Common - N-acetylglucosamine-6-phosphate deacetylase Meso_2863 118 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 110635933 Common cmk cytidylate kinase Meso_3607 205 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 110634477 Common - NAD-dependent epimerase/dehydratase Meso_2128 79 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 110635037 Common - ribonucleotide-diphosphate reductase subunit alpha Meso_2703 222 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 110635948 Common - fumarate lyase Meso_3622 238 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 110634919 Common - glycoside hydrolase, family 16 Meso_2578 44 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 110635598 Common leuD isopropylmalate isomerase small subunit Meso_3269 212 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 110634048 Common - 2-octaprenyl-6-methoxyphenyl hydroxylase Meso_1696 121 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 110633211 Common - glutathione-dependent formaldehyde-activating, GFA Meso_0854 58 COG3791 COG3791, Uncharacterized conserved protein Function unknown 110634432 Common - GatB/Yqey Meso_2082 150 COG1610 COG1610, Uncharacterized conserved protein Function unknown 110635601 Common - thioredoxin Meso_3272 231 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 110633070 Common glyQ glycyl-tRNA synthetase subunit alpha Meso_0713 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 110635020 Common - Urease accessory protein UreF Meso_2686 84 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 110633503 Common - ATP dependent DNA ligase Meso_1150 89 COG3285 COG3285, Predicted eukaryotic-type DNA primase DNA replication, recombination, and repair 110632834 Common - molybdopterin dehydrogenase, FAD-binding Meso_0473 96 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 110635048 Common - amidase Meso_2714 218 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 110632759 Common - Hydantoinase/oxoprolinase Meso_0398 116 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110632865 Common - conjugal transfer protein trbJ Meso_0505 22 COG5314 COG5314, Conjugal transfer/entry exclusion protein Intracellular trafficking and secretion 110634874 Common - protein of unknown function DUF81 Meso_2533 40 COG0730 COG0730, Predicted permeases General function prediction only 110632487 Common - transcriptional regulator, LysR family Meso_0125 20 COG0583 LysR, Transcriptional regulator Transcription 110633097 Common - Invasion associated locus B Meso_0740 13 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 110634266 Common rpsF 30S ribosomal protein S6 Meso_1916 199 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 110634966 Common - phenylalanine/histidine ammonia-lyase Meso_2632 109 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 110633433 Common - 6-phosphogluconate dehydrogenase, NAD-binding Meso_1079 24 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 110634352 Common - cell division protein FtsA Meso_2002 187 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 110634179 Common - transcriptional regulator, GntR family Meso_1829 135 COG1802 GntR, Transcriptional regulators Transcription 110633143 Common - hypothetical protein Meso_0786 9 None None None 110634004 Common - protein of unknown function DUF486 Meso_1652 53 COG3169 COG3169, Uncharacterized protein conserved in bacteria Function unknown 110633283 Nonpathogen - hypothetical protein Meso_0929 1 None None None 110636019 Common - ABC transporter related Meso_3694 248 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 110636010 Common - short chain dehydrogenase Meso_3685 236 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 110635192 Common - radical SAM enzyme, Cfr family Meso_2859 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 110635188 Common - extracellular solute-binding protein, family 1 Meso_2855 32 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 110632567 Common - hypothetical protein Meso_0205 6 None None None 110634328 Common - molybdopterin biosynthesis MoaE Meso_1978 153 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 110634908 Common - outer membrane protein, hypothetical Meso_2567 21 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 110635181 Common - transcriptional regulator, MerR family Meso_2848 143 COG0789 SoxR, Predicted transcriptional regulators Transcription 110635754 Common rpmF 50S ribosomal protein L32 Meso_3426 120 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 110632676 Common - protein of unknown function DUF6, transmembrane Meso_0315 105 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 110636097 Common - binding-protein-dependent transport systems inner membrane component Meso_3772 148 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 110635728 Common - dihydrolipoamide dehydrogenase Meso_3400 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 110636171 Common - Lytic transglycosylase, catalytic Meso_3847 143 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 110632952 Common - diguanylate cyclase/phosphodiesterase Meso_0595 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 110635808 Common aroE shikimate 5-dehydrogenase Meso_3480 223 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 110636028 Common - PfkB Meso_3703 172 COG3892 COG3892, Uncharacterized protein conserved in bacteria Function unknown 110633301 Common - hypothetical protein Meso_0947 18 COG3216 COG3216, Uncharacterized protein conserved in bacteria Function unknown 110634469 Common - Extensin-like Meso_2120 36 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 110634321 Common - hypothetical protein Meso_1971 7 COG5511 COG5511, Bacteriophage capsid protein General function prediction only 110634988 Common - short-chain dehydrogenase/reductase SDR Meso_2654 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110634069 Common aat leucyl/phenylalanyl-tRNA--protein transferase Meso_1717 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 110633749 Common uvrA excinuclease ABC subunit A Meso_1396 243 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 110635346 Common - hypothetical protein Meso_3017 3 None None None 110634439 Common - putative transcriptional regulator, ArsR family Meso_2090 69 COG0640 ArsR, Predicted transcriptional regulators Transcription 110634499 Common - prolipoprotein diacylglyceryl transferase Meso_2150 203 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 110632402 Common - polar amino acid ABC transporter, inner membrane subunit Meso_0040 176 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 110636301 Common - polar amino acid ABC transporter, inner membrane subunit Meso_3977 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 110634769 Common - Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit Meso_2428 160 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 110635168 Common - protein of unknown function DUF182 Meso_2835 48 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 110636045 Common - transcriptional regulator, GntR family Meso_3720 141 COG1802 GntR, Transcriptional regulators Transcription 110634090 Common - nicotinate phosphoribosyltransferase Meso_1739 60 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 110632511 Common - hypothetical protein Meso_0149 40 COG3247 HdeD, Uncharacterized conserved protein Function unknown 110633620 Common - isocitrate dehydrogenase Meso_1267 63 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 110635082 Common - histidinol-phosphate phosphatase, putative Meso_2748 152 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 110633515 Common - putative agmatinase Meso_1162 130 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 110634382 Common - response regulator receiver protein Meso_2032 26 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 110634020 Common rplN 50S ribosomal protein L14 Meso_1668 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 110636160 Common - hypothetical protein Meso_3836 13 None None None 110636223 Common - Twin-arginine translocation pathway signal Meso_3899 33 COG0716 FldA, Flavodoxins Energy production and conversion 110633966 Common - D-amino acid aminotransferase Meso_1614 200 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 110633092 Common - 1-deoxy-D-xylulose-5-phosphate synthase Meso_0735 230 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 110634647 Common - ABC transporter related Meso_2302 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 110636367 Common - ATP-dependent helicase HrpB Meso_4043 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 110635520 Common - conserved hypothetical selenoprotein Meso_3191 32 COG3526 COG3526, Uncharacterized protein conserved in bacteria Posttranslational modification, protein turnover, chaperones 110634940 Common - type I secretion system ATPase Meso_2599 249 COG4618 ArpD, ABC-type protease/lipase transport system, ATPase and permease components General function prediction only 110633549 Common - hypothetical protein Meso_1196 2 None None None 110633003 Common - glycosyl transferase, family 2 Meso_0646 7 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 110634440 Common - Acyl-CoA dehydrogenase, type 2-like Meso_2091 112 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 110635311 Common - protein of unknown function DUF886 Meso_2982 39 COG3758 COG3758, Uncharacterized protein conserved in bacteria Function unknown 110636281 Common - binding-protein-dependent transport systems inner membrane component Meso_3957 178 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 110635974 Common - hypothetical protein Meso_3649 4 None None None 110635179 Common - transcriptional regulator, LacI family Meso_2846 127 COG1609 PurR, Transcriptional regulators Transcription 110633936 Common - hydrolase, TatD family Meso_1584 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 110634392 Common - beta alanine--pyruvate transaminase Meso_2042 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 110634370 Common - Hydantoinase B/oxoprolinase Meso_2020 115 COG0146 HyuB, N-methylhydantoinase B/acetone carboxylase, alpha subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110634539 Common - 2-isopropylmalate synthase Meso_2190 211 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 110635399 Common - glutathione-dependent formaldehyde-activating, GFA Meso_3070 61 COG3791 COG3791, Uncharacterized conserved protein Function unknown 110636189 Common - transcriptional regulator, Crp/Fnr family Meso_3865 115 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 110634460 Common - transcriptional regulator, LysR family Meso_2111 175 COG0583 LysR, Transcriptional regulator Transcription 110634218 Common - iron-containing alcohol dehydrogenase Meso_1868 173 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 110633180 Common - hypothetical protein Meso_0823 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 110635481 Common - Cupin 2, conserved barrel Meso_3152 17 None None None 110635639 Common - ornithine cyclodeaminase/mu-crystallin Meso_3311 86 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 110632541 Common - UspA Meso_0179 44 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 110634732 Common - argininosuccinate lyase Meso_2390 217 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 110635065 Common - two component, sigma54 specific, transcriptional regulator, Fis family Meso_2731 218 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 110636180 Common - hypothetical protein Meso_3856 12 None None None 110635359 Common - hypothetical protein Meso_3030 10 None None None 110633128 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Meso_0771 30 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 110636199 Common - UspA Meso_3875 73 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 110633770 Common - protein of unknown function DUF463, YcjX-like protein Meso_1417 42 COG3106 COG3106, Predicted ATPase General function prediction only 110632412 Common - TRAP dicarboxylate transporter- DctP subunit Meso_0050 37 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 110635458 Common - aldo/keto reductase Meso_3129 205 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 110632945 Common - Invasion associated locus B Meso_0588 5 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 110632436 Common - Twin-arginine translocation pathway signal Meso_0074 209 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 110633542 Nonpathogen - hypothetical protein Meso_1189 2 None None None 110634910 Common - transcriptional regulator, GntR family Meso_2569 117 COG1802 GntR, Transcriptional regulators Transcription 110634291 Nonpathogen - hypothetical protein Meso_1941 1 None None None 110634759 Common - transcriptional regulator, AsnC family Meso_2418 140 COG1522 Lrp, Transcriptional regulators Transcription 110633869 Common - hypothetical protein Meso_1516 44 None None None 110633152 Common - histidine kinase Meso_0795 119 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 110633809 Common - sugar fermentation stimulation protein A Meso_1456 107 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 110634258 Nonpathogen - hypothetical protein Meso_1908 1 None None None 110632491 Common - hypothetical protein Meso_0129 153 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 110632562 Common - hypothetical protein Meso_0200 4 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 110635926 Common - undecaprenyl pyrophosphate phosphatase Meso_3600 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 110635966 Common - Enoyl-CoA hydratase/isomerase Meso_3640 178 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 110636089 Common - hypothetical protein Meso_3764 2 None None None 110632496 Common - transport system permease protein Meso_0134 189 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 110633196 Common - ABC transporter related Meso_0839 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 110632628 Common - hypothetical protein Meso_0267 11 None None None 110636308 Common - 3'-5' exonuclease Meso_3984 107 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 110633926 Nonpathogen - hypothetical protein Meso_1574 2 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 110634421 Common - protein of unknown function DUF1486 Meso_2071 17 None None None 110635070 Common - protein of unknown function DUF107 Meso_2736 42 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 110632414 Common - monooxygenase, FAD-binding Meso_0052 79 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 110632783 Common hisS histidyl-tRNA synthetase Meso_0422 249 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110635820 Common - ATP-dependent protease peptidase subunit Meso_3492 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 110632392 Common - Methyltransferase type 12 Meso_0030 34 COG4976 COG4976, Predicted methyltransferase (contains TPR repeat) General function prediction only 110634416 Common - ABC transporter related Meso_2066 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 110635430 Common - PRC-barrel Meso_3101 33 COG1873 COG1873, Uncharacterized conserved protein Function unknown 110634052 Common - DSBA oxidoreductase Meso_1700 86 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 110634156 Common - sec-independent translocase Meso_1805 27 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 110633417 Common - Demethylmenaquinone methyltransferase-like Meso_1063 71 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 110633521 Nonpathogen - hypothetical protein Meso_1168 1 None None None 110633836 Common - signal transduction histidine kinase Meso_1483 38 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 110635483 Common - amidohydrolase Meso_3154 165 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 110633897 Common - glutamine synthetase, type I Meso_1544 224 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 110632674 Common - aldehyde dehydrogenase Meso_0313 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 110634810 Common - asparagine synthase (glutamine-hydrolyzing) Meso_2469 164 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 110633179 Common - short chain dehydrogenase Meso_0822 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110633426 Common - Uncharacterized protein UPF0065 Meso_1072 75 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 110635781 Common - hypothetical protein Meso_3453 162 COG1576 COG1576, Uncharacterized conserved protein Function unknown 110632985 Common - hypothetical protein Meso_0628 13 COG5649 COG5649, Uncharacterized conserved protein Function unknown 110634033 Common - elongation factor G Meso_1681 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 110632779 Common - protein of unknown function DUF195 Meso_0418 122 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 110636101 Common - transcriptional regulator, DeoR family Meso_3776 65 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 110635840 Common - hypothetical protein Meso_3512 9 None None None 110635251 Common - cytochrome c, class I Meso_2922 57 COG3474 COG3474, Cytochrome c2 Energy production and conversion 110632993 Common - hypothetical protein Meso_0636 9 None None None 110633720 Common - L-serine dehydratase 1 Meso_1367 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 110632688 Common - luciferase-like Meso_0327 61 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 110636365 Common - response regulator receiver protein Meso_4041 154 COG4567 COG4567, Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain Signal transduction mechanisms / Transcription 110633992 Common - molybdenum cofactor biosynthesis protein C Meso_1640 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 110633752 Common - multiple antibiotic resistance (MarC)-related proteins Meso_1399 155 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 110632667 Common fliG flagellar motor switch protein G Meso_0306 122 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 110634078 Common - ferripyochelin binding protein-like Meso_1727 202 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 110632438 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Meso_0076 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 110635890 Common - transcriptional regulator, MarR family Meso_3564 66 COG1846 MarR, Transcriptional regulators Transcription 110634793 Nonpathogen - hypothetical protein Meso_2452 3 None None None 110634885 Common - amidohydrolase Meso_2544 200 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 110634618 Nonpathogen - hypothetical protein Meso_2272 2 None None None 110636036 Common - NADPH-dependent FMN reductase Meso_3711 76 COG0431 COG0431, Predicted flavoprotein General function prediction only 110634070 Common - cellulase-like protein Meso_1718 28 COG4765 COG4765, Uncharacterized protein conserved in bacteria Function unknown 110635836 Common - FAD dependent oxidoreductase Meso_3508 99 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 110633315 Nonpathogen - hypothetical protein Meso_0961 1 None None None 110634534 Common - putative glutathione S-transferase Meso_2185 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 110632695 Common - transcriptional regulator, GntR family Meso_0334 87 COG1802 GntR, Transcriptional regulators Transcription 110632665 Common - surface presentation of antigens (SPOA) protein Meso_0304 12 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 110634367 Common - Lytic transglycosylase, catalytic Meso_2017 110 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 110635874 Common - short-chain dehydrogenase/reductase SDR Meso_3546 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110632621 Common - 2-deoxy-D-gluconate 3-dehydrogenase Meso_0260 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110635173 Common - phage SPO1 DNA polymerase-related protein Meso_2840 148 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 110635858 Common - phosphoribosyltransferase Meso_3530 73 COG1926 COG1926, Predicted phosphoribosyltransferases General function prediction only 110635949 Common - TRAP transporter solute receptor, TAXI family Meso_3623 76 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 110636133 Common - DNA polymerase III, alpha subunit Meso_3809 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 110632637 Common flaF flagellar biosynthesis regulatory protein FlaF Meso_0276 14 COG5442 FlaF, Flagellar biosynthesis regulator FlaF Cell motility and secretion 110636402 Common - alpha/beta hydrolase fold Meso_4078 109 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 110633288 Common - DoxX Meso_0934 29 COG2259 COG2259, Predicted membrane protein Function unknown 110635149 Common - peptidase C26 Meso_2816 114 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 110634846 Common - fumarylacetoacetate (FAA) hydrolase Meso_2505 176 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 110632927 Common - transcriptional regulator, GntR family Meso_0568 137 COG1802 GntR, Transcriptional regulators Transcription 110634813 Common - choline/carnitine/betaine transporter Meso_2472 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 110633831 Common - Twin-arginine translocation pathway signal Meso_1478 10 COG1409 Icc, Predicted phosphohydrolases General function prediction only 110634959 Common - binding-protein-dependent transport systems inner membrane component Meso_2625 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110634201 Common - Hydantoinase/oxoprolinase Meso_1851 120 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110634992 Common - Twin-arginine translocation pathway signal Meso_2658 18 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 110632915 Nonpathogen - hypothetical protein Meso_0556 1 None None None 110634474 Common - thioesterase superfamily Meso_2125 118 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 110635437 Nonpathogen - hypothetical protein Meso_3108 1 None None None 110633793 Common - TonB-dependent heme/hemoglobin receptor family protein Meso_1440 122 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 110635226 Common - ABC-2 type transporter Meso_2893 141 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 110633177 Common - alpha/beta hydrolase fold Meso_0820 71 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 110635580 Common - hypothetical protein Meso_3251 16 COG3904 COG3904, Predicted periplasmic protein Function unknown 110634762 Common - glycoside hydrolase, family 13-like Meso_2421 174 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 110632968 Common - hypothetical protein Meso_0611 10 COG4655 COG4655, Predicted membrane protein Function unknown 110632872 Common - hypothetical protein Meso_0512 14 None None None 110634894 Nonpathogen - hypothetical protein Meso_2553 1 None None None 110633243 Nonpathogen - hypothetical protein Meso_0886 1 None None None 110633172 Common - putative sulfonate transport system substrate-binding protein Meso_0815 24 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 110636354 Common - malic enzyme Meso_4030 211 COG0281 SfcA, Malic enzyme Energy production and conversion 110633828 Common - dihydroorotase Meso_1475 86 COG0418 PyrC, Dihydroorotase Nucleotide transport and metabolism 110635207 Common - lipopolysaccharide biosynthesis Meso_2874 46 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 110633917 Common - polar amino acid ABC transporter, inner membrane subunit Meso_1564 174 COG4160 ArtM, ABC-type arginine/histidine transport system, permease component Amino acid transport and metabolism 110633883 Nonpathogen - hypothetical protein Meso_1530 4 None None None 110636426 Common - ribosomal protein S20 Meso_4102 169 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 110635219 Common - transcriptional regulator, AsnC family Meso_2886 170 COG1522 Lrp, Transcriptional regulators Transcription 110634901 Common - pantoate--beta-alanine ligase Meso_2560 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 110635421 Nonpathogen - hypothetical protein Meso_3092 1 None None None 110635682 Common - GCN5-related N-acetyltransferase Meso_3354 120 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 110632884 Common - phage transcriptional regulator, AlpA Meso_0524 24 COG3311 AlpA, Predicted transcriptional regulator Transcription 110633718 Common gatA aspartyl/glutamyl-tRNA amidotransferase subunit A Meso_1365 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 110635156 Common - coenzyme A transferase Meso_2823 40 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 110632793 Common - Patatin Meso_0432 57 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 110633110 Common - hypothetical protein Meso_0753 128 COG1678 COG1678, Putative transcriptional regulator Transcription 110636150 Nonpathogen - hypothetical protein Meso_3826 1 None None None 110633455 Nonpathogen - hypothetical protein Meso_1101 1 None None None 110635826 Common hisE phosphoribosyl-ATP pyrophosphatase Meso_3498 137 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 110632423 Common - hypothetical protein Meso_0061 34 COG3812 COG3812, Uncharacterized protein conserved in bacteria Function unknown 110634146 Common - protein of unknown function DUF498 Meso_1795 31 COG3737 COG3737, Uncharacterized conserved protein Function unknown 110634485 Common - hypothetical protein Meso_2136 9 None None None 110635813 Common - import inner membrane translocase, subunit Tim44 Meso_3485 44 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 110633168 Common - FAD-binding 9, siderophore-interacting Meso_0811 61 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 110635880 Common - Endoribonuclease L-PSP Meso_3553 30 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 110632539 Common - TRAP transporter solute receptor, TAXI family Meso_0177 89 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 110635637 Common - Pyridoxal-5'-phosphate-dependent enzyme, beta subunit Meso_3309 227 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 110633367 Common - MaoC-like dehydratase Meso_1013 86 COG2030 MaoC, Acyl dehydratase Lipid metabolism 110635294 Common - short-chain dehydrogenase/reductase SDR Meso_2965 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110633238 Common - hypothetical protein Meso_0881 14 COG5436 COG5436, Predicted integral membrane protein Function unknown 110635664 Nonpathogen - hypothetical protein Meso_3336 1 None None None 110634185 Common - extracellular solute-binding protein, family 5 Meso_1835 157 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 110632950 Common - sarcosine oxidase, alpha subunit family Meso_0593 185 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 110634544 Common - alpha/beta hydrolase fold Meso_2195 100 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 110634404 Common - transcriptional regulator, BadM/Rrf2 family Meso_2054 48 COG1959 COG1959, Predicted transcriptional regulator Transcription 110636166 Common - replication protein A Meso_3842 32 COG5534 COG5534, Plasmid replication initiator protein DNA replication, recombination, and repair 110634503 Common - hypothetical protein Meso_2154 8 None None None 110635490 Common - D-3-phosphoglycerate dehydrogenase Meso_3161 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 110633036 Common - chaperone protein DnaK Meso_0679 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 110636330 Common - periplasmic solute binding protein Meso_4006 165 COG4531 ZnuA, ABC-type Zn2+ transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 110636390 Common - cytochrome bd ubiquinol oxidase, subunit I Meso_4066 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 110632525 Common - extracellular solute-binding protein, family 1 Meso_0163 131 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 110633912 Common - protein of unknown function DUF6, transmembrane Meso_1559 91 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 110632978 Common - response regulator receiver protein Meso_0621 72 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110635897 Common - two component transcriptional regulator, winged helix family Meso_3571 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110632405 Common - hypothetical protein Meso_0043 10 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 110632513 Common - pyrroline-5-carboxylate reductase Meso_0151 212 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 110634876 Common - beta-lactamase-like Meso_2535 203 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 110634384 Common - alpha/beta hydrolase fold Meso_2034 79 COG2267 PldB, Lysophospholipase Lipid metabolism 110635711 Common - conserved hypothetical/unknown signal peptide protein Meso_3383 12 None None None 110635429 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Meso_3100 37 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 110632658 Common flgC flagellar basal body rod protein FlgC Meso_0297 124 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 110633461 Common - hypothetical protein Meso_1107 20 None None None 110635289 Common - Carboxymuconolactone decarboxylase Meso_2960 76 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 110635059 Common - 5'-Nucleotidase-like Meso_2725 142 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 110632649 Common - flagellin-like Meso_0288 120 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 110633231 Common - conserved hypothetical cytosolic protein Meso_0874 21 None None None 110635337 Nonpathogen - hypothetical protein Meso_3008 1 COG3847 Flp, Flp pilus assembly protein, pilin Flp Intracellular trafficking and secretion 110633065 Common - peptidase S49 Meso_0708 180 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 110633107 Common rnhA ribonuclease H Meso_0750 174 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 110632907 Common - hypothetical protein Meso_0547 5 None None None 110633000 Common - putative iron-regulated protein Meso_0643 37 COG3487 IrpA, Uncharacterized iron-regulated protein Inorganic ion transport and metabolism 110634734 Common - argininosuccinate lyase Meso_2392 215 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 110633473 Common - Ppx/GppA phosphatase Meso_1120 183 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 110632761 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Meso_0400 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 110635441 Common - ABC transporter related Meso_3112 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 110634339 Nonpathogen - hypothetical protein Meso_1989 1 None None None 110634106 Common - DNA polymerase III subunit chi Meso_1755 40 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 110634345 Common - branched-chain amino acid transport Meso_1995 11 COG4541 COG4541, Predicted membrane protein Function unknown 110632846 Common - acyltransferase 3 Meso_0485 97 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 110632692 Nonpathogen - hypothetical protein Meso_0331 7 None None None 110633660 Nonpathogen - hypothetical protein Meso_1307 1 None None None 110635105 Nonpathogen - hypothetical protein Meso_2772 4 None None None 110635096 Common - dTDP-glucose 4,6-dehydratase Meso_2762 229 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 110635846 Common - ErfK/YbiS/YcfS/YnhG Meso_3518 85 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 110634038 Common - exodeoxyribonuclease III Xth Meso_1686 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 110635885 Common - binding-protein-dependent transport systems inner membrane component Meso_3558 148 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 110633757 Common - peptidyl-prolyl cis-trans isomerase, cyclophilin type Meso_1404 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 110634224 Common - hypothetical protein Meso_1874 5 None None None 110634706 Common - putative NreB protein Meso_2363 52 None None None 110636177 Common - conjugal transfer protein Meso_3853 22 COG5268 TrbD, Type IV secretory pathway, TrbD component Cell motility and secretion / Intracellular trafficking and secretion 110635678 Common - lipolytic enzyme, G-D-S-L Meso_3350 107 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 110633227 Common - putative monovalent cation/H+ antiporter subunit G Meso_0870 8 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 110636268 Common - drug resistance transporter, Bcr/CflA subfamily Meso_3944 147 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 110632597 Common - hypothetical protein Meso_0236 4 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 110634595 Common - UspA Meso_2248 62 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 110633572 Common - CsbD-like Meso_1219 40 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 110636201 Common - phosphoribosylpyrophosphate synthetase Meso_3877 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 110633558 Common - hypothetical protein Meso_1205 2 None None None 110633375 Common - protein of unknown function DUF1006 Meso_1021 60 COG3214 COG3214, Uncharacterized protein conserved in bacteria Function unknown 110633727 Common - O-antigen polymerase Meso_1374 13 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 110636073 Common - hypothetical protein Meso_3748 10 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 110636246 Common - transporter-associated region Meso_3922 214 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 110632729 Common - iron-sulfur cluster binding protein Meso_0368 95 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 110634861 Common - GntR-like Meso_2520 128 COG2186 FadR, Transcriptional regulators Transcription 110635284 Common - sigma54 specific transcriptional regulator, Fis family Meso_2955 174 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 110634847 Common - 3,4-dihydroxyphenylacetate 2,3-dioxygenase Meso_2506 35 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 110632811 Common - oxidoreductase-like Meso_0450 171 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 110633974 Common - CinA-like Meso_1622 193 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 110635299 Common - coenzyme A transferase Meso_2970 41 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 110635772 Common trmD tRNA (guanine-N(1)-)-methyltransferase Meso_3444 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 110633025 Common - protein of unknown function DUF45 Meso_0668 153 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 110636078 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Meso_3753 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 110633322 Common - glutathione-dependent formaldehyde-activating, GFA Meso_0968 63 COG3791 COG3791, Uncharacterized conserved protein Function unknown 110633818 Common - RNA polymerase sigma factor RpoD Meso_1465 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 110634629 Common - efflux transporter, RND family, MFP subunit Meso_2283 65 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 110632592 Common - hypothetical protein Meso_0231 3 None None None 110635693 Nonpathogen - hypothetical protein Meso_3365 1 None None None 110633856 Nonpathogen - hypothetical protein Meso_1503 1 None None None 110634622 Common - heat shock protein Hsp20 Meso_2276 153 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 110635701 Common - polyhydroxyalkonate synthesis repressor, PhaR Meso_3373 65 COG5394 COG5394, Uncharacterized protein conserved in bacteria Function unknown 110633205 Nonpathogen - hypothetical protein Meso_0848 2 None None None 110636212 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Meso_3888 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 110636208 Common - glyceraldehyde-3-phosphate dehydrogenase Meso_3884 36 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 110634526 Common - NUDIX hydrolase Meso_2177 131 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 110635118 Common - oxidoreductase-like Meso_2785 157 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 110634043 Common - inner-membrane translocator Meso_1691 108 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 110633616 Common recA recombinase A Meso_1263 228 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 110634863 Common - hypothetical protein Meso_2522 33 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 110633384 Common - NADH dehydrogenase subunit I Meso_1030 195 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 110634129 Common - cysteine desulfurases, SufS subfamily Meso_1778 240 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 110635320 Common - protein of unknown function DUF196 Meso_2991 17 None None None 110633357 Common - phosphoribosyl-AMP cyclohydrolase Meso_1003 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 110634611 Common - hypothetical protein Meso_2265 25 COG5622 COG5622, Protein required for attachment to host cells Cell motility and secretion 110634906 Common thiE thiamine-phosphate pyrophosphorylase Meso_2565 198 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 110636239 Common - malate synthase G Meso_3915 78 COG2225 AceB, Malate synthase Energy production and conversion 110632854 Common - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase Meso_0494 40 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 110633679 Common - Activator of Hsp90 ATPase-like Meso_1326 33 COG3832 COG3832, Uncharacterized conserved protein Function unknown 110636425 Common - enoyl-CoA hydratase Meso_4101 188 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 110636232 Nonpathogen - hypothetical protein Meso_3908 5 None None None 110635404 Common - transcriptional regulator, ArsR family Meso_3075 88 COG0640 ArsR, Predicted transcriptional regulators Transcription 110633510 Common - exopolysaccharide transport protein family Meso_1157 66 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 110633138 Common - UspA Meso_0781 77 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 110635959 Common - binding-protein-dependent transport systems inner membrane component Meso_3633 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110632476 Common - Tetratricopeptide TPR_2 Meso_0114 9 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 110634788 Common - cytoplasmic chaperone TorD Meso_2447 26 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 110635008 Common - 4-alpha-glucanotransferase Meso_2674 119 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 110636059 Common - glucose-methanol-choline oxidoreductase Meso_3734 96 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 110632571 Nonpathogen - hypothetical protein Meso_0209 1 None None None 110635001 Common - heavy metal translocating P-type ATPase Meso_2667 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 110633087 Common - chorismate synthase Meso_0730 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 110633345 Common - hypothetical protein Meso_0991 21 COG3823 COG3823, Glutamine cyclotransferase Posttranslational modification, protein turnover, chaperones 110632556 Common - phage integrase Meso_0194 29 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 110636337 Common - coproporphyrinogen III oxidase Meso_4013 211 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 110636329 Common - ABC transporter related Meso_4005 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 110632707 Common - Twin-arginine translocation pathway signal Meso_0346 80 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 110635329 Common - PTSINtr with GAF domain, PtsP Meso_3000 235 COG3605 PtsP, Signal transduction protein containing GAF and PtsI domains Signal transduction mechanisms 110633983 Common - Septum formation initiator Meso_1631 28 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 110632825 Common - Fmu (Sun) Meso_0464 207 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 110633221 Common - putative monovalent cation/H+ antiporter subunit A Meso_0864 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 110634833 Common - Cupin 2, conserved barrel Meso_2492 16 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 110634086 Common - carboxyl transferase Meso_1735 214 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 110635608 Common - L-carnitine dehydratase/bile acid-inducible protein F Meso_3280 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 110634197 Common - peptidase M19, renal dipeptidase Meso_1847 102 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 110636170 Common - hypothetical protein Meso_3846 23 COG5489 COG5489, Uncharacterized conserved protein Function unknown 110633262 Common - protein of unknown function DUF6, transmembrane Meso_0908 105 COG2962 RarD, Predicted permeases General function prediction only 110635123 Nonpathogen - hypothetical protein Meso_2790 1 None None None 110632550 Common - protein tyrosine phosphatase Meso_0188 51 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 110634691 Common - ParB-like nuclease Meso_2347 121 COG1475 Spo0J, Predicted transcriptional regulators Transcription 110632642 Common - Lytic transglycosylase, catalytic Meso_0281 42 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 110633658 Nonpathogen - hypothetical protein Meso_1305 1 None None None 110633412 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Meso_1058 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 110634636 Common - transcriptional regulator, ArsR family Meso_2290 102 COG0640 ArsR, Predicted transcriptional regulators Transcription 110635963 Common - BFD-like (2Fe-2S)-binding region Meso_3637 51 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 110635378 Common - protein of unknown function DUF112, transmembrane Meso_3049 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 110632601 Common - Microcystin-dependent protein-like Meso_0240 16 COG4675 MdpB, Microcystin-dependent protein Function unknown 110633445 Common - TRAP transporter, 4TM/12TM fusion protein Meso_1091 129 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 110635730 Common - GumN Meso_3402 44 COG3735 COG3735, Uncharacterized protein conserved in bacteria Function unknown 110633082 Common - hypothetical protein Meso_0725 5 None None None 110633999 Common - ATP12 ATPase Meso_1647 33 COG5387 COG5387, Chaperone required for the assembly of the mitochondrial F1-ATPase Posttranslational modification, protein turnover, chaperones 110633944 Common - ABC transporter related Meso_1592 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 110634298 Common - GntR-like Meso_1948 137 COG2186 FadR, Transcriptional regulators Transcription 110634302 Common - binding-protein-dependent transport systems inner membrane component Meso_1952 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110633481 Common - RDD domain containing protein Meso_1128 15 COG1714 COG1714, Predicted membrane protein/domain Function unknown 110632533 Common - PAS/PAC sensor signal transduction histidine kinase Meso_0171 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110634560 Common - hypothetical protein Meso_2211 29 COG5385 COG5385, Uncharacterized protein conserved in bacteria Function unknown 110632716 Common fumC fumarate hydratase Meso_0355 221 COG0114 FumC, Fumarase Energy production and conversion 110632464 Nonpathogen - hypothetical protein Meso_0102 1 None None None 110633044 Nonpathogen - hypothetical protein Meso_0687 1 None None None 110634718 Common - Twin-arginine translocation pathway signal Meso_2375 205 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 110635522 Common - hypothetical protein Meso_3193 19 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 110634067 Common - acetyl-CoA carboxylase, biotin carboxyl carrier protein Meso_1715 190 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 110635315 Common - imidazolonepropionase Meso_2986 104 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 110633094 Common - (Uracil-5)-methyltransferase Meso_0737 191 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 110633257 Common - periplasmic sensor signal transduction histidine kinase Meso_0903 217 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110635172 Common - MOFRL Meso_2839 86 COG2379 GckA, Putative glycerate kinase Carbohydrate transport and metabolism 110633314 Common - hypothetical protein Meso_0960 6 None None None 110633045 Common - Integral membrane protein TerC Meso_0688 44 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 110636258 Common rpsO 30S ribosomal protein S15 Meso_3934 217 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 110636087 Common - Dak phosphatase Meso_3762 23 None None None 110632514 Common - tetrahydrofolate dehydrogenase/cyclohydrolase Meso_0152 223 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 110634492 Common - SPW repeat Meso_2143 10 None None None 161621420 Common - aconitate hydratase Meso_3357 221 COG1048 AcnA, Aconitase A Energy production and conversion 110633261 Common - aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding Meso_0907 107 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 110635683 Common - hypothetical protein Meso_3355 30 None None None 110634081 Common - Aspartyl/Asparaginyl beta-hydroxylase Meso_1730 38 COG3555 COG3555, Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases Posttranslational modification, protein turnover, chaperones 110634446 Common - protein of unknown function DUF559 Meso_2097 44 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 110633159 Common - putative decarboxylase Meso_0802 19 COG4032 COG4032, Predicted thiamine-pyrophosphate-binding protein General function prediction only 110633985 Common - 2-dehydro-3-deoxyphosphooctonate aldolase Meso_1633 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 110632611 Nonpathogen - hypothetical protein Meso_0250 1 None None None 110632499 Common - outer membrane autotransporter barrel domain Meso_0137 97 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 110634998 Common - dihydropyrimidinase Meso_2664 209 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 110636190 Nonpathogen - hypothetical protein Meso_3866 1 None None None 110634575 Common - NAD(P)H dehydrogenase (quinone) Meso_2227 55 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 110633327 Common - hypothetical protein Meso_0973 8 None None None 110635431 Common - diacylglycerol kinase, catalytic region Meso_3102 105 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 110634735 Common - NAD/NADP octopine/nopaline dehydrogenase Meso_2393 24 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 110633522 Common clpP ATP-dependent Clp protease proteolytic subunit Meso_1169 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 110633968 Common - two component, sigma54 specific, transcriptional regulator, Fis family Meso_1616 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 110635901 Common - phosphocarrier, HPr family Meso_3575 147 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 110636063 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Meso_3738 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 110632931 Common - transcriptional regulator, AraC family Meso_0573 127 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 110633194 Common - transcriptional regulator, LysR family Meso_0837 165 COG0583 LysR, Transcriptional regulator Transcription 110634372 Common - Methyltransferase type 11 Meso_2022 67 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 110634032 Common - elongation factor Tu Meso_1680 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 110634423 Common - protein of unknown function DUF541 Meso_2073 110 COG2968 COG2968, Uncharacterized conserved protein Function unknown 110633154 Common - response regulator receiver protein Meso_0797 201 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 110634741 Common - Uncharacterized protein UPF0065 Meso_2399 76 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 110632967 Common - peptidase A24A, prepilin type IV Meso_0610 11 COG4960 CpaA, Flp pilus assembly protein, protease CpaA Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 110635347 Common - polysaccharide biosynthesis protein Meso_3018 59 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 110636119 Common - AAA ATPase, central region Meso_3794 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 110634274 Nonpathogen - hypothetical protein Meso_1924 1 None None None 110632488 Common - FAD dependent oxidoreductase Meso_0126 129 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 110634610 Common - transport-associated Meso_2264 41 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 110632605 Nonpathogen - hypothetical protein Meso_0244 1 None None None 110636225 Common - short-chain dehydrogenase/reductase SDR Meso_3901 238 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 110634263 Nonpathogen - hypothetical protein Meso_1913 4 None None None 110635406 Common - glutathione S-transferase-like Meso_3077 94 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 110636423 Common - phosphopentomutase Meso_4099 70 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 110634230 Nonpathogen - hypothetical protein Meso_1880 1 None None None 110633358 Common folE GTP cyclohydrolase I Meso_1004 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 110636345 Common - PfkB Meso_4021 147 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 110636297 Common - DegT/DnrJ/EryC1/StrS aminotransferase Meso_3973 194 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 110636025 Common - SMP-30/Gluconolaconase/LRE-like region Meso_3700 74 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 110634649 Common - binding-protein-dependent transport systems inner membrane component Meso_2304 155 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 110634079 Common - hypothetical protein Meso_1728 20 None None None 110635066 Common - protein of unknown function DUF882 Meso_2732 62 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 110634387 Common - acetolactate synthase 2 catalytic subunit Meso_2037 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 110632994 Common - putative integral membrane protein TIGR02587 Meso_0637 9 COG4711 COG4711, Predicted membrane protein Function unknown 110634256 Common - (2Fe-2S)-binding Meso_1906 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 110635578 Nonpathogen - hypothetical protein Meso_3249 1 None None None 110635370 Common - OpgC protein Meso_3041 35 COG4645 COG4645, Uncharacterized protein conserved in bacteria Function unknown 110635539 Common - hypothetical protein Meso_3210 6 COG5468 COG5468, Predicted secreted (periplasmic) protein Function unknown 110632373 Common - phosphate uptake regulator, PhoU Meso_0011 200 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 110635605 Common - fumarylacetoacetate (FAA) hydrolase Meso_3277 174 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 110632677 Common - carbohydrate kinase, thermoresistant glucokinase family Meso_0316 80 COG3265 GntK, Gluconate kinase Carbohydrate transport and metabolism 110634212 Common - binding-protein-dependent transport systems inner membrane component Meso_1862 204 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 110636251 Common - protein of unknown function DUF150 Meso_3927 168 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 110633437 Common - magnesium transporter Meso_1083 170 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 110634754 Common - transcriptional regulator, AraC family Meso_2413 142 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 110635026 Common - hypothetical protein Meso_2692 17 COG4641 COG4641, Uncharacterized protein conserved in bacteria Function unknown 110635075 Common - protein of unknown function DUF459 Meso_2741 28 COG2845 COG2845, Uncharacterized protein conserved in bacteria Function unknown 110634677 Common - protein of unknown function DUF736 Meso_2332 26 COG5489 COG5489, Uncharacterized conserved protein Function unknown 110633747 Common - protein of unknown function DUF72 Meso_1394 89 COG1801 COG1801, Uncharacterized conserved protein Function unknown 110632441 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Meso_0079 201 COG0388 COG0388, Predicted amidohydrolase General function prediction only 110635478 Common - extracellular solute-binding protein, family 3 Meso_3149 137 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 110633123 Common - protein of unknown function DUF1159 Meso_0766 26 COG5389 COG5389, Uncharacterized protein conserved in bacteria Function unknown 110635873 Common - fumarylacetoacetate (FAA) hydrolase Meso_3545 180 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 110632769 Common - transcriptional regulator, IclR family Meso_0408 117 COG1414 IclR, Transcriptional regulator Transcription 110632743 Common - pyrimidine 5'-nucleotidase Meso_0382 46 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 110635302 Common - transcriptional regulator, LysR family Meso_2973 192 COG0583 LysR, Transcriptional regulator Transcription 110635854 Common - protein of unknown function DUF892 Meso_3526 39 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 110632894 Common - hypothetical protein Meso_0534 39 None None None 110632753 Common - GCN5-related N-acetyltransferase Meso_0392 74 COG3153 COG3153, Predicted acetyltransferase General function prediction only 110633961 Common - aldo/keto reductase Meso_1609 167 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 110635053 Common - aminotransferase, class I and II Meso_2719 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 110635595 Common - protein of unknown function DUF1025 Meso_3266 50 COG3824 COG3824, Uncharacterized protein conserved in bacteria Function unknown 110632527 Common - binding-protein-dependent transport systems inner membrane component Meso_0165 218 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 110635107 Common - NAD-dependent epimerase/dehydratase Meso_2774 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 110635335 Common - phosphoribosyltransferase Meso_3006 146 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 110634708 Common - peptidase M24 Meso_2365 228 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 110633544 Common - protein of unknown function DUF955 Meso_1191 36 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 110632453 Common - two component transcriptional regulator, LuxR family Meso_0091 175 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 110634605 Common - transcriptional regulator, XRE family Meso_2258 13 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 110632625 Common - inner-membrane translocator Meso_0264 105 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 110633535 Nonpathogen - hypothetical protein Meso_1182 1 None None None 110633864 Common - protein of unknown function DUF81 Meso_1511 63 COG0730 COG0730, Predicted permeases General function prediction only 110632460 Common - O-succinylhomoserine sulfhydrylase Meso_0098 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 110633867 Common - hypothetical protein Meso_1514 7 None None None 110635862 Common - cytochrome c oxidase, subunit III Meso_3534 158 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 110633933 Common - thymidylate kinase Meso_1581 233 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 110633230 Common - Chromosomal replication initiator, DnaA-like Meso_0873 52 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 110635358 Common - short chain dehydrogenase Meso_3029 233 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 110634105 Common - ABC transporter related Meso_1754 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 110634237 Common - hypothetical protein Meso_1887 9 None None None 110632781 Common hisZ ATP phosphoribosyltransferase regulatory subunit Meso_0420 81 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 110635999 Common - ornithine cyclodeaminase Meso_3674 15 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 110636186 Common - transcriptional regulator, LysR family Meso_3862 185 COG0583 LysR, Transcriptional regulator Transcription 110635361 Common - Rhomboid-like protein Meso_3032 103 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 110633285 Common - acyl-CoA dehydrogenase-like Meso_0931 169 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 110636112 Common - hypothetical protein Meso_3787 9 None None None 110633213 Common - methylmalonyl-CoA mutase Meso_0856 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 110635044 Common - ABC transporter related Meso_2710 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 110636229 Common - transcriptional regulator, LysR family Meso_3905 129 COG0583 LysR, Transcriptional regulator Transcription 110635450 Common - putative phosphate transporter (ABC superfamily, peri-bind) Meso_3121 119 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 110634837 Common - ABC transporter related Meso_2496 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 110635252 Common - ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components-like Meso_2923 15 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 110633571 Nonpathogen - hypothetical protein Meso_1218 1 None None None 110634912 Common - Cupin 2, conserved barrel Meso_2571 20 COG4297 COG4297, Uncharacterized protein containing double-stranded beta helix domain Function unknown 110633565 Common - phage uncharacterized protein Meso_1212 30 COG5410 COG5410, Uncharacterized protein conserved in bacteria Function unknown 110636099 Common - short-chain dehydrogenase/reductase SDR Meso_3774 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110635391 Common xerD site-specific tyrosine recombinase XerD Meso_3062 223 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 110634641 Common - Amidase Meso_2296 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 110632886 Common - hypothetical protein Meso_0526 11 None None None 110633931 Common - rare lipoprotein A Meso_1579 137 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 110634436 Common - protein of unknown function, zinc metallopeptidase putative Meso_2086 87 COG2321 COG2321, Predicted metalloprotease General function prediction only 110634620 Common - sigma 54 modulation protein/ribosomal protein S30EA Meso_2274 20 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 110636020 Common - Methyltransferase type 12 Meso_3695 34 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 110633694 Common - TrpR binding protein WrbA Meso_1341 97 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 110635208 Common - O-antigen polymerase Meso_2875 24 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 110634698 Common - hypothetical protein Meso_2354 3 None None None 110635455 Nonpathogen - hypothetical protein Meso_3126 2 None None None 110633728 Common - glycosyl transferase, family 25 Meso_1375 20 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 110635546 Common - F0F1 ATP synthase subunit gamma Meso_3217 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 110633057 Nonpathogen - hypothetical protein Meso_0700 1 None None None 110635979 Common - inner-membrane translocator Meso_3654 112 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 110634169 Common rpoB DNA-directed RNA polymerase subunit beta Meso_1819 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 110634567 Common - oxidoreductase-like Meso_2218 190 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 110634936 Nonpathogen - hypothetical protein Meso_2595 4 None None None 110632870 Common - transcriptional regulator, XRE family Meso_0510 27 COG1396 HipB, Predicted transcriptional regulators Transcription 110636157 Nonpathogen - hypothetical protein Meso_3833 1 None None None 110636128 Nonpathogen - hypothetical protein Meso_3804 3 None None None 110635654 Common - ABC transporter related Meso_3326 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 110633721 Common - Uncharacterised conserved protein UCP032025 Meso_1368 31 COG5458 COG5458, Uncharacterized conserved protein Function unknown 110636195 Common - Cyclopropane-fatty-acyl-phospholipid synthase Meso_3871 135 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 110635499 Common - OmpA/MotB Meso_3170 149 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 110633919 Common - transcriptional regulator, AsnC family Meso_1566 156 COG1522 Lrp, Transcriptional regulators Transcription 110636405 Common - binding-protein-dependent transport systems inner membrane component Meso_4081 218 COG4239 COG4239, ABC-type uncharacterized transport system, permease component General function prediction only 110634127 Common - FeS assembly scaffold SufA Meso_1776 164 COG0316 IscA, Uncharacterized conserved protein Function unknown 110636273 Common - protein of unknown function DUF1498 Meso_3949 18 COG3822 COG3822, ABC-type sugar transport system, auxiliary component General function prediction only 110634398 Common - transcriptional regulator, AraC family Meso_2048 68 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 110633276 Common - hypothetical protein Meso_0922 2 None None None 110633639 Nonpathogen - hypothetical protein Meso_1286 3 COG5497 COG5497, Predicted secreted protein Function unknown 110632433 Common - transcriptional regulator, GntR family Meso_0071 217 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 110633647 Common - 4-diphosphocytidyl-2C-methyl-D-erythritol synthase Meso_1294 104 COG2068 COG2068, Uncharacterized MobA-related protein General function prediction only 110635970 Common - hypothetical protein Meso_3644 4 None None None 110633615 Common - OmpA/MotB Meso_1262 172 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 110633641 Common - Extracellular ligand-binding receptor Meso_1288 35 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 110635941 Common - TRAP dicarboxylate transporter, DctM subunit Meso_3615 127 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 110634096 Common - GCN5-related N-acetyltransferase Meso_1745 94 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 110635663 Common - 3-hydroxybutyrate dehydrogenase Meso_3335 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110633608 Common dnaE DNA polymerase III subunit alpha Meso_1255 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 110634487 Common - beta-lactamase-like Meso_2138 214 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 110632879 Common - conjugal transfer protein precursor Meso_0519 32 COG4959 TraF, Type IV secretory pathway, protease TraF Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 110636030 Common - periplasmic binding protein/LacI transcriptional regulator Meso_3705 99 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 110633626 Common - glutaredoxin-like protein Meso_1273 127 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 110634559 Common - Uncharacterised conserved protein UCP033924 Meso_2210 22 COG5400 COG5400, Uncharacterized protein conserved in bacteria Function unknown 110632573 Nonpathogen - hypothetical protein Meso_0211 1 None None None 110635952 Common - aminotransferase, class I and II Meso_3626 236 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 110634617 Common - membrane bound O-acyl transferase, MBOAT Meso_2271 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 110635923 Common - NAD-dependent epimerase/dehydratase Meso_3597 105 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 110633017 Common - exopolysaccharide transport protein family Meso_0660 134 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 110636295 Common - dihydrodipicolinate synthetase Meso_3971 177 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 110633663 Common - ABC transporter related Meso_1310 249 COG4172 COG4172, ABC-type uncharacterized transport system, duplicated ATPase component General function prediction only 110635895 Common - methylated-DNA--protein-cysteine methyltransferase Meso_3569 177 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 110632428 Common - binding-protein-dependent transport systems inner membrane component Meso_0066 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110632924 Nonpathogen - GCN5-related N-acetyltransferase Meso_0565 3 COG0456 RimI, Acetyltransferases General function prediction only 110635613 Common - Enoyl-CoA hydratase/isomerase Meso_3285 178 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 110634029 Common rplD 50S ribosomal protein L4 Meso_1677 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 110633653 Common - transcriptional regulator, LysR family Meso_1300 187 COG0583 LysR, Transcriptional regulator Transcription 110633533 Nonpathogen - hypothetical protein Meso_1180 2 None None None 110634982 Common - extracellular solute-binding protein, family 5 Meso_2648 214 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 110634114 Common gmk guanylate kinase Meso_1763 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 110632383 Common - 3-hydroxyacyl-CoA dehydrogenase, NAD-binding Meso_0021 170 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 110633797 Common - ABC transporter related Meso_1444 249 COG4559 COG4559, ABC-type hemin transport system, ATPase component Inorganic ion transport and metabolism 110634687 Nonpathogen - hypothetical protein Meso_2343 10 None None None 110634924 Common - 4'-phosphopantetheinyl transferase Meso_2583 72 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 110634113 Common ksgA dimethyladenosine transferase Meso_1762 247 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 110633689 Common - peptidase S14, ClpP Meso_1336 29 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 110634973 Common - protein of unknown function DUF917 Meso_2639 8 COG3535 COG3535, Uncharacterized conserved protein Function unknown 110635263 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Meso_2934 50 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 110634281 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Meso_1931 64 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 110633761 Common - hypothetical protein Meso_1408 124 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 110634183 Common - binding-protein-dependent transport systems inner membrane component Meso_1833 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110633950 Common - glycerol kinase Meso_1598 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 110634831 Nonpathogen - hypothetical protein Meso_2490 9 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 110634962 Common - phenylalanine/histidine ammonia-lyase Meso_2628 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 110633957 Common - sugar ABC transporter, periplasmic sugar-binding protein Meso_1605 19 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 110636017 Common - glycosyl transferase, group 1 Meso_3692 126 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110634380 Common - hypothetical protein Meso_2030 5 COG5586 COG5586, Uncharacterized conserved protein Function unknown 110633843 Common - Lysine exporter protein (LYSE/YGGA) Meso_1490 60 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 110633296 Common smpB SsrA-binding protein Meso_0942 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 110635203 Common - hypothetical protein Meso_2870 5 None None None 110633165 Common - binding-protein-dependent transport systems inner membrane component Meso_0808 158 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 110635526 Common - glutamine amidotransferase Meso_3197 127 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 110632821 Common - binding-protein-dependent transport systems inner membrane component Meso_0460 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110633321 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Meso_0967 68 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 110635464 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Meso_3135 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 110633077 Common - protein of unknown function DUF1326 Meso_0720 17 COG5588 COG5588, Uncharacterized conserved protein Function unknown 110635993 Common - ABC transporter related Meso_3668 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 110634717 Common - peptidase M24 Meso_2374 205 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 110634174 Common nusG transcription antitermination protein NusG Meso_1824 215 COG0250 NusG, Transcription antiterminator Transcription 110635590 Common - ABC transporter, ATPase subunit, ThiQ subfamily Meso_3261 249 COG3840 ThiQ, ABC-type thiamine transport system, ATPase component Coenzyme metabolism 110633407 Common - aldehyde dehydrogenase Meso_1053 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 110633308 Common - Twin-arginine translocation pathway signal Meso_0954 70 COG3211 PhoX, Predicted phosphatase General function prediction only 110634013 Common rpsE 30S ribosomal protein S5 Meso_1661 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 110636143 Common - hypothetical protein Meso_3819 60 None None None 110633497 Common - hypothetical protein Meso_1144 28 None None None 110634806 Common - 4-hydroxyphenylacetate 3-hydroxylase Meso_2465 49 COG2368 COG2368, Aromatic ring hydroxylase Secondary metabolites biosynthesis, transport, and catabolism 110634002 Common - recombination factor protein RarA Meso_1650 239 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 110635915 Common - aldehyde dehydrogenase Meso_3589 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 110636121 Nonpathogen - hypothetical protein Meso_3796 1 None None None 110635767 Common - glyceraldehyde-3-phosphate dehydrogenase, type I Meso_3439 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 110633336 Common - small multidrug resistance protein Meso_0982 129 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 110633591 Common - outer membrane protein, 31 kDa Meso_1238 24 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 110634948 Common - hypothetical protein Meso_2610 9 None None None 110633742 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase Meso_1389 177 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 110635806 Common - hypothetical protein Meso_3478 112 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 110633772 Common - transcriptional regulators, TraR/DksA family Meso_1419 161 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 110635550 Common - transcriptional regulator, MarR family Meso_3221 131 COG1846 MarR, Transcriptional regulators Transcription 110634137 Common - hypothetical protein Meso_1786 33 COG3164 COG3164, Predicted membrane protein Function unknown 110634196 Common - Uncharacterized protein UPF0065 Meso_1846 75 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 110632558 Nonpathogen - hypothetical protein Meso_0196 1 None None None 110633600 Common - hypothetical protein Meso_1247 8 None None None 110633970 Common - nitrogen metabolism transcriptional regulator, NtrC, Fis Family Meso_1618 219 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 110633029 Common - nickel-cobalt-cadmium resistance protein NCCN Meso_0672 21 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 110635780 Common - peptidase M23B Meso_3452 130 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 110633777 Common - cysteine synthase A Meso_1424 225 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 110636331 Common - hypothetical protein Meso_4007 21 None None None 110635559 Common - inorganic pyrophosphatase Meso_3230 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 110634466 Common - glycosyl transferase, group 1 Meso_2117 217 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110635389 Common - protein of unknown function DUF949 Meso_3060 52 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 110635087 Common - Capsule polysaccharide biosynthesis Meso_2753 29 COG3562 KpsS, Capsule polysaccharide export protein Cell envelope biogenesis, outer membrane 110634525 Common - Polynucleotide adenylyltransferase region Meso_2176 202 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 110635504 Common - 4-hydroxybenzoyl-CoA thioesterase Meso_3175 122 COG0824 FcbC, Predicted thioesterase General function prediction only 110633803 Common - major facilitator superfamily MFS_1 Meso_1450 114 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 110634852 Common - protein of unknown function DUF112, transmembrane Meso_2511 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 110632737 Common - putative inner membrane protein translocase component YidC Meso_0376 214 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 110635508 Common ruvC Holliday junction resolvase Meso_3179 197 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 110634016 Common rpsH 30S ribosomal protein S8 Meso_1664 247 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 110633163 Common - ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components-like Meso_0806 71 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 110633684 Nonpathogen - hypothetical protein Meso_1331 1 None None None 110634583 Common - acetate kinase Meso_2235 161 COG0282 ackA, Acetate kinase Energy production and conversion 110633837 Common - intracellular protease, PfpI family Meso_1484 168 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 110632569 Nonpathogen - hypothetical protein Meso_0207 1 None None None 110634453 Common - methylated-DNA--protein-cysteine methyltransferase Meso_2104 171 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 110636131 Common - hypothetical protein Meso_3807 23 COG4544 COG4544, Uncharacterized conserved protein Function unknown 110634121 Common - Nucleotidyl transferase Meso_1770 225 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 110634579 Common - UspA Meso_2231 56 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 110636303 Common - MlrC-like Meso_3979 32 COG5476 COG5476, Uncharacterized conserved protein Function unknown 110635552 Common - carbonic anhydrase Meso_3223 150 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 110635380 Common - major facilitator superfamily MFS_1 Meso_3051 117 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 110633581 Nonpathogen - hypothetical protein Meso_1228 5 None None None 110635778 Common - protein of unknown function DUF610, YibQ Meso_3450 61 COG2861 COG2861, Uncharacterized protein conserved in bacteria Function unknown 110634976 Common - Rhodanese-like Meso_2642 145 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 110635238 Nonpathogen - hypothetical protein Meso_2908 1 None None None 110634325 Common uvrC excinuclease ABC subunit C Meso_1975 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 110634807 Common - transcriptional regulator, AraC family Meso_2466 44 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 110633826 Common - putative RNA polymerase, sigma-24 subunit, ECF subfamily Meso_1473 46 COG4941 COG4941, Predicted RNA polymerase sigma factor containing a TPR repeat domain Transcription 110633340 Common - alanine racemase Meso_0986 198 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 110635412 Common - homoserine O-succinyltransferase Meso_3083 64 COG1897 MetA, Homoserine trans-succinylase Amino acid transport and metabolism 110633735 Common tsf elongation factor Ts Meso_1382 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 110634836 Common - ABC transporter related Meso_2495 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 110633813 Common - hypothetical protein Meso_1460 8 COG3184 COG3184, Uncharacterized protein conserved in bacteria Function unknown 110633453 Common - ETC complex I subunit conserved region Meso_1099 36 None None None 110634592 Common - pseudoazurin Meso_2245 24 COG3794 PetE, Plastocyanin Energy production and conversion 110635449 Common - phosphate ABC transporter, inner membrane subunit PstC Meso_3120 233 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 110635015 Common - urease, gamma subunit Meso_2681 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 110634665 Common - conjugal transfer protein trbJ Meso_2320 22 COG5314 COG5314, Conjugal transfer/entry exclusion protein Intracellular trafficking and secretion 110633792 Nonpathogen - hypothetical protein Meso_1439 7 None None None 110633136 Common - polysaccharide biosynthesis protein CapD Meso_0779 173 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 110635967 Common - binding-protein-dependent transport systems inner membrane component Meso_3641 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110636106 Common - sorbitol dehydrogenase Meso_3781 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110633470 Common - monooxygenase, FAD-binding Meso_1117 91 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 110636233 Common - Cupin 2, conserved barrel Meso_3909 67 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 110633674 Common - putative phosphohistidine phosphatase, SixA Meso_1321 16 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 110633343 Common glpX fructose 1,6-bisphosphatase II Meso_0989 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 110634888 Common - glutathione S-transferase-like Meso_2547 103 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 110634247 Nonpathogen - hypothetical protein Meso_1897 3 None None None 110635201 Common - inner-membrane translocator Meso_2868 46 COG4120 COG4120, ABC-type uncharacterized transport system, permease component General function prediction only 110635984 Common - adenosine deaminase Meso_3659 107 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 110633901 Nonpathogen - hypothetical protein Meso_1548 1 None None None 110634692 Common - hypothetical protein Meso_2348 11 None None None 110633023 Common - tryptophan synthase subunit beta Meso_0666 225 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 110633223 Common - putative monovalent cation/H+ antiporter subunit C Meso_0866 74 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 110632901 Common - helicase-like Meso_0541 105 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 110634508 Common - translation-associated GTPase Meso_2159 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 110633512 Common - hypothetical protein Meso_1159 7 None None None 110634242 Common - HNH endonuclease Meso_1892 22 None None None 110634249 Nonpathogen - hypothetical protein Meso_1899 1 None None None 110632421 Common - aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding Meso_0059 112 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 110633490 Common - riboflavin synthase subunit alpha Meso_1137 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 110635314 Common - histidine ammonia-lyase Meso_2985 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 110632656 Common flgG flagellar basal body rod protein FlgG Meso_0295 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 110632791 Common - peptidase M16-like Meso_0430 192 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 110634501 Common - protein of unknown function DUF152 Meso_2152 182 COG1496 COG1496, Uncharacterized conserved protein Function unknown 110636342 Common - Antibiotic biosynthesis monooxygenase Meso_4018 10 COG1359 COG1359, Uncharacterized conserved protein Function unknown 110633659 Nonpathogen - hypothetical protein Meso_1306 1 None None None 110633821 Common - 3-demethylubiquinone-9 3-methyltransferase Meso_1468 64 COG3865 COG3865, Uncharacterized protein conserved in bacteria Function unknown 110635210 Common - glycosyl transferase, group 1 Meso_2877 209 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110634187 Common - BFD-like (2Fe-2S)-binding region Meso_1837 53 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 110633447 Common - transcriptional regulator, LacI family Meso_1093 126 COG1609 PurR, Transcriptional regulators Transcription 110635882 Common - ATPase, BadF/BadG/BcrA/BcrD type Meso_3555 41 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 110633101 Nonpathogen - hypothetical protein Meso_0744 1 None None None 110633463 Nonpathogen - hypothetical protein Meso_1109 1 None None None 110635144 Common - indolepyruvate ferredoxin oxidoreductase Meso_2811 93 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 110633244 Common - protein of unknown function DUF955 Meso_0887 36 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 110633583 Nonpathogen - hypothetical protein Meso_1230 3 None None None 110635444 Common - ROK domain containing protein Meso_3115 160 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 110632777 Common - Twin-arginine translocation pathway signal Meso_0416 72 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 110634292 Common - multi-sensor hybrid histidine kinase Meso_1942 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110633111 Common - protein of unknown function DUF1232 Meso_0754 30 COG3339 COG3339, Uncharacterized conserved protein Function unknown 110635900 Common - PTS system fructose subfamily IIA component Meso_3574 99 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 110635423 Common - response regulator receiver protein Meso_3094 220 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 110633682 Nonpathogen - hypothetical protein Meso_1329 1 None None None 110633483 Common - enoyl-CoA hydratase Meso_1130 140 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 110636410 Common - 3-deoxy-manno-octulosonate cytidylyltransferase Meso_4086 137 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 110634781 Common - WD-40 repeat Meso_2440 96 COG2319 COG2319, FOG: WD40 repeat General function prediction only 110633389 Common - NADH dehydrogenase subunit N Meso_1035 208 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 110633924 Common valS valyl-tRNA synthetase Meso_1571 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110633871 Nonpathogen - conserved repeat domain Meso_1518 7 COG4719 COG4719, Uncharacterized protein conserved in bacteria Function unknown 110635129 Common - acriflavin resistance protein Meso_2796 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 110634209 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Meso_1859 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 110632381 Common - DSBA oxidoreductase Meso_0019 43 COG3917 NahD, 2-hydroxychromene-2-carboxylate isomerase Secondary metabolites biosynthesis, transport, and catabolism 110632551 Common - hypothetical protein Meso_0189 31 COG5328 COG5328, Uncharacterized protein conserved in bacteria Function unknown 110633419 Common - Malate/L-lactate dehydrogenase Meso_1065 67 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 110636207 Common - hypothetical protein Meso_3883 5 None None None 110632710 Nonpathogen - hypothetical protein Meso_0349 6 None None None 110634498 Common - protein of unknown function DUF526 Meso_2149 32 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 110635288 Common - NIPSNAP domain containing protein Meso_2959 10 None None None 110634565 Common - protein of unknown function DUF1153 Meso_2216 27 None None None 110636406 Common - binding-protein-dependent transport systems inner membrane component Meso_4082 219 COG4174 COG4174, ABC-type uncharacterized transport system, permease component General function prediction only 110633799 Common - GCN5-related N-acetyltransferase Meso_1446 13 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 110632535 Common - hypothetical protein Meso_0173 20 COG5276 COG5276, Uncharacterized conserved protein Function unknown 110633391 Common - beta-lactamase-like Meso_1037 154 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 110635848 Common - Isoprenylcysteine carboxyl methyltransferase Meso_3520 67 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 110635334 Common - glutaredoxin 3 Meso_3005 118 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 110634589 Common - arginine deiminase Meso_2241 56 COG2235 ArcA, Arginine deiminase Amino acid transport and metabolism 110633692 Common - UspA Meso_1339 44 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 110635233 Nonpathogen - hypothetical protein Meso_2903 6 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 110633855 Common - Methyltransferase type 11 Meso_1502 108 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 110636275 Common - NLP/P60 Meso_3951 65 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 110632805 Common tdh L-threonine 3-dehydrogenase Meso_0444 212 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 110635094 Common - glucose-1-phosphate thymidylyltransferase Meso_2760 232 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 110632475 Common - type III secretion exporter Meso_0113 111 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 110633266 Common - lipolytic enzyme, G-D-S-L Meso_0912 14 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 110633068 Common - Polyprenyl synthetase Meso_0711 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 110632763 Common - binding-protein-dependent transport systems inner membrane component Meso_0402 218 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110634627 Common - ABC transporter related Meso_2281 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 110634300 Common - extracellular solute-binding protein, family 5 Meso_1950 179 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 110635729 Nonpathogen - hypothetical protein Meso_3401 1 None None None 110635147 Common - Exopolysaccharide synthesis, ExoD Meso_2814 34 COG3932 COG3932, Uncharacterized ABC-type transport system, permease components General function prediction only 110636067 Common - molybdopterin oxidoreductase Meso_3742 167 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 110634402 Common - 3-carboxy-cis,cis-muconate cycloisomerase Meso_2052 230 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 110632959 Common - type II secretion system protein Meso_0602 73 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 110632867 Common - conjugal transfer protein trbB Meso_0507 22 COG5268 TrbD, Type IV secretory pathway, TrbD component Cell motility and secretion / Intracellular trafficking and secretion 110635282 Common - Enoyl-CoA hydratase/isomerase Meso_2953 182 COG0447 MenB, Dihydroxynaphthoic acid synthase Coenzyme metabolism 110635006 Common - hypothetical protein Meso_2672 10 None None None 110633687 Common - NUDIX hydrolase Meso_1334 32 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 110636240 Common - peptidase M22, glycoprotease Meso_3916 190 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 110634478 Nonpathogen - hypothetical protein Meso_2129 1 None None None 110633434 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Meso_1080 229 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 110636047 Common - transcriptional regulator, LysR family Meso_3722 192 COG0583 LysR, Transcriptional regulator Transcription 110634663 Common - TrbL/VirB6 plasmid conjugal transfer protein Meso_2318 24 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 110635519 Common rpmE 50S ribosomal protein L31 Meso_3190 131 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 110633908 Common - glutathione S-transferase-like Meso_1555 100 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 110635713 Nonpathogen - hypothetical protein Meso_3385 3 None None None 110633784 Common - glycosyl transferase, family 51 Meso_1431 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 110635631 Common - transcriptional regulator, IclR family Meso_3303 93 COG1414 IclR, Transcriptional regulator Transcription 110636266 Common - protein of unknown function DUF1058 Meso_3942 45 COG3807 COG3807, Uncharacterized protein conserved in bacteria Function unknown 110634191 Common - transcriptional regulator, IclR family Meso_1841 111 COG1414 IclR, Transcriptional regulator Transcription 110635597 Common - HpcH/HpaI aldolase Meso_3268 110 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 110633005 Common - glycoside hydrolase, family 16 Meso_0648 16 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 110636247 Common - transcriptional regulator, XRE family Meso_3923 40 COG1396 HipB, Predicted transcriptional regulators Transcription 110635602 Nonpathogen - hypothetical protein Meso_3274 1 None None None 110632700 Common - TRAP dicarboxylate transporter- DctP subunit Meso_0339 74 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 110634433 Common - carbamoyl phosphate synthase small subunit Meso_2083 236 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 110632826 Common - transcriptional regulator, LysR family Meso_0465 181 COG0583 LysR, Transcriptional regulator Transcription 110635116 Common - hypothetical protein Meso_2783 4 None None None 110632922 Common - extracellular solute-binding protein, family 5 Meso_0563 212 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 110632929 Common - hypothetical protein Meso_0570 20 COG2253 COG2253, Uncharacterized conserved protein Function unknown 110634340 Nonpathogen - hypothetical protein Meso_1990 1 None None None 110634737 Common - peptidase M24 Meso_2395 192 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 110634849 Common - 5-carboxymethyl-2-hydroxymuconate isomerase Meso_2508 31 COG3232 HpaF, 5-carboxymethyl-2-hydroxymuconate isomerase Amino acid transport and metabolism 110633613 Common - Isoprenylcysteine carboxyl methyltransferase Meso_1260 45 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 110633876 Common - acetyl-CoA acetyltransferase Meso_1523 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 110635029 Nonpathogen - hypothetical protein Meso_2695 1 None None None 110633373 Common - protein of unknown function DUF188 Meso_1019 97 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 110632633 Common flhA flagellar biosynthesis protein A Meso_0272 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 110635162 Common - ureidoglycolate hydrolase Meso_2829 35 COG3194 DAL3, Ureidoglycolate hydrolase Nucleotide transport and metabolism 110635296 Common - transcriptional regulator, IclR family Meso_2967 110 COG1414 IclR, Transcriptional regulator Transcription 110632664 Common - flagellar motor protein MotA Meso_0303 100 COG1291 MotA, Flagellar motor component Cell motility and secretion 110633118 Common - lipoprotein, hypothetical Meso_0761 9 None None None 110633319 Common cysS cysteinyl-tRNA synthetase Meso_0965 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110635859 Nonpathogen - hypothetical protein Meso_3531 3 None None None 110634865 Common - aldehyde dehydrogenase Meso_2524 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 110636368 Common - ABC transporter related Meso_4044 249 COG4136 COG4136, ABC-type uncharacterized transport system, ATPase component General function prediction only 110632675 Common - deoxyribose-phosphate aldolase Meso_0314 128 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 110632709 Nonpathogen - hypothetical protein Meso_0348 5 None None None 110633586 Nonpathogen - hypothetical protein Meso_1233 2 None None None 110633072 Common - Sua5/YciO/YrdC/YwlC family protein Meso_0715 234 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 110634548 Common - anthranilate synthase Meso_2199 237 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 110636419 Nonpathogen - Flp/Fap pilin component Meso_4095 1 COG3847 Flp, Flp pilus assembly protein, pilin Flp Intracellular trafficking and secretion 110635815 Common - Smr protein/MutS2 Meso_3487 27 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 110635625 Common - Dimethylmenaquinone methyltransferase Meso_3297 78 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 110634772 Common - formate dehydrogenase family accessory protein FdhD Meso_2431 136 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 110634896 Common - nicotinate-nucleotide pyrophosphorylase Meso_2555 204 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 110636167 Common - hypothetical protein Meso_3843 23 None None None 110634878 Common - Rhodanese-like Meso_2537 62 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 110636039 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Meso_3714 12 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 110633047 Common - hypothetical protein Meso_0690 11 None None None 110635111 Common - glycosyl transferase, group 1 Meso_2778 21 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110635747 Common - Heparinase II/III-like Meso_3419 45 COG5360 COG5360, Uncharacterized protein conserved in bacteria Function unknown 110634144 Nonpathogen - hypothetical protein Meso_1793 5 None None None 110632723 Common - hypothetical protein Meso_0362 25 COG3671 COG3671, Predicted membrane protein Function unknown 110632975 Common - type I secretion system ATPase Meso_0618 249 COG4618 ArpD, ABC-type protease/lipase transport system, ATPase and permease components General function prediction only 110632393 Common - putative mRNA 3-end processing factor Meso_0031 75 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 110632770 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Meso_0409 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 110634956 Common - protein of unknown function DUF427 Meso_2621 53 COG2343 COG2343, Uncharacterized protein conserved in bacteria Function unknown 110632455 Common - protein of unknown function DUF952 Meso_0093 46 COG3502 COG3502, Uncharacterized protein conserved in bacteria Function unknown 110632719 Common - chaperonin Cpn10 Meso_0358 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 110634751 Nonpathogen - hypothetical protein Meso_2409 7 None None None 110635681 Common - protein of unknown function UPF0005 Meso_3353 119 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 110632857 Common - phage transcriptional regulator, AlpA Meso_0497 19 COG3311 AlpA, Predicted transcriptional regulator Transcription 110636393 Common - hypothetical protein Meso_4069 11 COG4729 COG4729, Uncharacterized conserved protein Function unknown 110634153 Common surE stationary phase survival protein SurE Meso_1802 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 110633270 Common - AMP nucleosidase Meso_0916 54 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 110634987 Common - iron-containing alcohol dehydrogenase Meso_2653 165 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 110635829 Common - hypothetical protein Meso_3501 112 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 110634107 Common - leucyl aminopeptidase Meso_1756 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 110635638 Common - alanine racemase-like Meso_3310 69 COG3616 COG3616, Predicted amino acid aldolase or racemase Amino acid transport and metabolism 110632507 Common - putative transmembrane anti-sigma factor Meso_0145 25 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 110636005 Common - multi-sensor hybrid histidine kinase Meso_3680 226 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110633914 Common - molybdopterin-guanine dinucleotide biosynthesis protein B Meso_1561 111 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 110634761 Common - amidohydrolase Meso_2420 173 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 110635827 Common - pantothenate kinase Meso_3499 77 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 110634798 Common - transcriptional regulator, LuxR family Meso_2457 20 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 110635042 Common - binding-protein-dependent transport systems inner membrane component Meso_2708 149 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 110633705 Common - hypothetical protein Meso_1352 27 COG5349 COG5349, Uncharacterized protein conserved in bacteria Function unknown 110635871 Common - acyl-CoA synthetase Meso_3543 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110635371 Common - glucosyltransferase MdoH Meso_3042 56 COG2943 MdoH, Membrane glycosyltransferase Cell envelope biogenesis, outer membrane 110632599 Common - hypothetical protein Meso_0238 4 None None None 110634967 Common - Twin-arginine translocation pathway signal Meso_2633 148 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 110635794 Nonpathogen - hypothetical protein Meso_3466 1 None None None 110633835 Common - conserved hypothetical acid-shock protein Meso_1482 11 None None None 110636286 Common - ornithine cyclodeaminase Meso_3962 82 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 110635766 Common - potassium/proton antiporter Meso_3438 102 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 110632948 Common - sarcosine oxidase, beta subunit family Meso_0591 110 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 110632970 Nonpathogen - hypothetical protein Meso_0613 2 None None None 110634343 Common prmA ribosomal protein L11 methyltransferase Meso_1993 174 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 110634635 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Meso_2289 71 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 110636352 Common - phospholipase D/Transphosphatidylase Meso_4028 62 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 110633160 Common - thiamine pyrophosphate enzyme-like TPP-binding Meso_0803 58 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 110632844 Common - transcriptional regulator, TetR family Meso_0483 90 COG1309 AcrR, Transcriptional regulator Transcription 110635244 Common - Zn-dependent hydrolases of the beta-lactamase fold-like Meso_2914 88 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 110634055 Common - protein of unknown function DUF339 Meso_1703 32 COG2938 COG2938, Uncharacterized conserved protein Function unknown 110633361 Common thrS threonyl-tRNA synthetase Meso_1007 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110632965 Common - TadE-like Meso_0608 127 COG4963 CpaE, Flp pilus assembly protein, ATPase CpaE Intracellular trafficking and secretion 110635889 Common - maleylacetoacetate isomerase Meso_3563 85 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 110634102 Common - thymidylate synthase Meso_1751 144 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 110635720 Nonpathogen - protein of unknown function DUF1328 Meso_3392 1 None None None 110633034 Common pheT phenylalanyl-tRNA synthetase subunit beta Meso_0677 239 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 110633338 Common - Colicin V production protein Meso_0984 27 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 110634651 Common - isochorismatase hydrolase Meso_2306 85 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 110632690 Nonpathogen - hypothetical protein Meso_0329 1 None None None 110633895 Common - Mammalian cell entry related Meso_1542 102 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 110635137 Common - NAD(P) transhydrogenase, beta subunit Meso_2804 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 110634723 Common - Cys/Met metabolism pyridoxal-phosphate-dependent enzymes Meso_2381 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 110633994 Common - LexA repressor Meso_1642 169 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 110632685 Common - arsenate reductase Meso_0324 114 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 110634376 Common - lytic murein transglycosylase Meso_2026 99 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 110633596 Common - RNA polymerase sigma factor Meso_1243 137 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 110635746 Common - Fmu (Sun) Meso_3418 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 110632627 Common - putative sugar ABC transporter periplasmic sugar-binding protein ABC transporter Meso_0266 103 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 110633175 Common - transcriptional regulator, IclR family Meso_0818 119 COG1414 IclR, Transcriptional regulator Transcription 110634658 Common - transcriptional regulator, LysR family Meso_2313 180 COG0583 LysR, Transcriptional regulator Transcription 110635918 Common - dihydrodipicolinate reductase Meso_3592 210 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 110634203 Common - xenobiotic compound monooxygenase, DszA family, A subunit Meso_1853 72 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 110635036 Common - ribonucleotide-diphosphate reductase subunit beta Meso_2702 156 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 110633922 Common - type I secretion outer membrane protein, TolC family Meso_1569 103 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 110636381 Common - DNA polymerase III subunits gamma and tau Meso_4057 247 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 110633976 Common - lipoyl synthase Meso_1624 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 110635303 Common - ornithine cyclodeaminase/mu-crystallin Meso_2974 91 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 110635257 Common - 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Meso_2928 151 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 110634045 Common - ABC transporter related Meso_1693 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 110634978 Common - FAD dependent oxidoreductase Meso_2644 136 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 110633333 Common - CDP-diacylglycerol--serine O-phosphatidyltransferase Meso_0979 152 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 110635779 Common - carboxyl-terminal protease Meso_3451 182 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 110634361 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase Meso_2011 210 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 110635852 Nonpathogen - hypothetical protein Meso_3524 1 None None None 110635130 Common - MaoC-like dehydratase Meso_2797 65 COG2030 MaoC, Acyl dehydratase Lipid metabolism 110636083 Common - dihydrodipicolinate synthetase Meso_3758 227 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 110636061 Common - aminotransferase, class I and II Meso_3736 234 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 110634365 Common - S-adenosyl-methyltransferase MraW Meso_2015 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 110633504 Common - Ku domain containing protein Meso_1151 63 COG1273 COG1273, Uncharacterized conserved protein Function unknown 110636210 Common - phospholipase D/Transphosphatidylase Meso_3886 150 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 110632635 Common flgD flagellar basal body rod modification protein Meso_0274 107 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 110634414 Common - periplasmic binding protein Meso_2064 27 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 110633889 Common - malic enzyme Meso_1536 212 COG0281 SfcA, Malic enzyme Energy production and conversion 110633147 Common - transcriptional regulator, GntR family Meso_0790 130 COG1802 GntR, Transcriptional regulators Transcription 110632996 Common - hypothetical protein Meso_0639 19 None None None 110633425 Common - Mandelate racemase/muconate lactonizing enzyme-like Meso_1071 118 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 110634532 Nonpathogen - conserved hypothetical protein-putative cycloisomerase Meso_2183 5 None None None 110636373 Common - transcriptional regulator, ArsR family Meso_4049 81 COG0640 ArsR, Predicted transcriptional regulators Transcription 110635691 Common - Lysine exporter protein (LYSE/YGGA) Meso_3363 113 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 110636385 Common - hypothetical protein Meso_4061 9 COG3832 COG3832, Uncharacterized conserved protein Function unknown 110635364 Common - 3-hydroxybutyryl-CoA dehydrogenase Meso_3035 161 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 110635482 Common - short-chain dehydrogenase/reductase SDR Meso_3153 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110634801 Common - Methyltransferase type 11 Meso_2460 27 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 110632654 Common flgI flagellar basal body P-ring protein Meso_0293 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 110636312 Common - Protein required for attachment to host cells-like Meso_3988 10 COG5622 COG5622, Protein required for attachment to host cells Cell motility and secretion 110633121 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Meso_0764 36 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 110634077 Common - transglutaminase-like cysteine peptidase, BTLCP Meso_1726 20 COG3672 COG3672, Predicted periplasmic protein Function unknown 110633862 Common - gamma-glutamyltransferase Meso_1509 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 110635864 Common - ubiquinol oxidase, subunit II Meso_3536 122 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 110633499 Common - 3-oxoacyl-(acyl-carrier-protein) synthase III Meso_1146 211 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 110633845 Common - hypothetical protein Meso_1492 4 None None None 110635024 Nonpathogen - hypothetical protein Meso_2690 12 COG3664 XynB, Beta-xylosidase Carbohydrate transport and metabolism 110636253 Common - hypothetical protein Meso_3929 38 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 110632720 Common - methyladenine glycosylase Meso_0359 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 110635943 Common - Transketolase-like Meso_3617 220 COG3959 COG3959, Transketolase, N-terminal subunit Carbohydrate transport and metabolism 110636176 Common - Conjugal transfer protein TrbC Meso_3852 22 COG3838 VirB2, Type IV secretory pathway, VirB2 components (pilins) Intracellular trafficking and secretion 110633149 Common - type I secretion system ATPase Meso_0792 249 COG4618 ArpD, ABC-type protease/lipase transport system, ATPase and permease components General function prediction only 110632417 Common - maleylacetoacetate isomerase Meso_0055 58 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 110634607 Common - hypothetical protein Meso_2260 50 COG3174 COG3174, Predicted membrane protein Function unknown 110634778 Common - binding-protein-dependent transport systems inner membrane component Meso_2437 182 COG4662 TupA, ABC-type tungstate transport system, periplasmic component Coenzyme metabolism 110632745 Common - protein of unknown function DUF461 Meso_0384 90 COG4549 COG4549, Uncharacterized protein conserved in bacteria Function unknown 110634135 Common - protein of unknown function DUF1508 Meso_1784 16 COG3422 COG3422, Uncharacterized conserved protein Function unknown 110633142 Common - NAD-dependent epimerase/dehydratase Meso_0785 230 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 110633753 Common - DNA gyrase subunit A Meso_1400 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 110632529 Common - AsmA Meso_0167 26 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 110632623 Common - transcriptional regulator, LacI family Meso_0262 128 COG1609 PurR, Transcriptional regulators Transcription 110635368 Nonpathogen - hypothetical protein Meso_3039 1 COG5567 COG5567, Predicted small periplasmic lipoprotein Cell motility and secretion 110635632 Common - acetolactate synthase catalytic subunit Meso_3304 219 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 110634843 Common - phage SPO1 DNA polymerase-related protein Meso_2502 156 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 110632747 Common - conserved hypothetical protein 730 Meso_0386 106 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 110635921 Common mgsA methylglyoxal synthase Meso_3595 87 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 110632896 Common - hypothetical protein Meso_0536 7 None None None 110634408 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Meso_2058 45 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 110632755 Common def peptide deformylase Meso_0394 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 110634792 Common - formate dehydrogenase, gamma subunit Meso_2451 68 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 110633190 Common - sulfate adenylyltransferase subunit 2 Meso_0833 132 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 110634189 Common - FAD dependent oxidoreductase Meso_1839 111 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 110634643 Common - beta-lactamase Meso_2298 146 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 110635300 Common - L-carnitine dehydratase/bile acid-inducible protein F Meso_2971 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 110634035 Common rpsL 30S ribosomal protein S12 Meso_1683 240 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 110634523 Common - ABC transporter related Meso_2174 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 110633287 Common - histidinol-phosphate aminotransferase Meso_0933 224 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 110634142 Common - protein of unknown function DUF1127 Meso_1791 8 COG5457 COG5457, Uncharacterized conserved small protein Function unknown 110635356 Common - protein of unknown function DUF6, transmembrane Meso_3027 80 None None None 110634796 Common - transcriptional regulator, MarR family Meso_2455 40 COG1846 MarR, Transcriptional regulators Transcription 110634239 Common - uncharacterized phage protein Meso_1889 6 None None None 110633560 Nonpathogen - hypothetical protein Meso_1207 1 None None None 110634396 Common - binding-protein-dependent transport systems inner membrane component Meso_2046 158 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 110635708 Common rpoH2 RNA polymerase factor sigma-32 Meso_3380 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 110632451 Common - large conductance mechanosensitive channel protein Meso_0089 132 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 110632733 Common - protein of unknown function DUF558 Meso_0372 172 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 110635182 Common - heavy metal translocating P-type ATPase Meso_2849 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 110632957 Common - CheA signal transduction histidine kinases Meso_0600 224 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 110636415 Common recR recombination protein RecR Meso_4091 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 110634904 Common - thiamine biosynthesis protein ThiS Meso_2563 19 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 110635046 Common - protein of unknown function DUF1007 Meso_2712 27 COG3683 COG3683, ABC-type uncharacterized transport system, periplasmic component General function prediction only 110634438 Common - Activator of Hsp90 ATPase-like Meso_2089 36 COG3832 COG3832, Uncharacterized conserved protein Function unknown 110635977 Common - ABC transporter related Meso_3652 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 110632403 Common - extracellular solute-binding protein, family 3 Meso_0041 82 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 110632492 Common - ABC transporter related Meso_0130 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 110633903 Common - hypothetical protein Meso_1550 49 COG3577 COG3577, Predicted aspartyl protease General function prediction only 110633519 Common - CoA-binding Meso_1166 132 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 110634235 Common - phage Terminase Meso_1885 47 COG4626 COG4626, Phage terminase-like protein, large subunit General function prediction only 110636118 Common - Domain of unknown function DUF1738 Meso_3793 48 COG4227 COG4227, Antirestriction protein DNA replication, recombination, and repair 110632443 Common - glycosyl transferase, family 2 Meso_0081 186 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 110633714 Common - Holliday junction resolvase YqgF Meso_1361 174 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 110635225 Common - extracellular solute-binding protein, family 3 Meso_2892 5 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 110634494 Common - periplasmic sensor signal transduction histidine kinase Meso_2145 214 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110635997 Common - integration host factor, beta subunit Meso_3672 207 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 110635476 Common - ABC transporter related Meso_3147 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 110636090 Common - luciferase-like Meso_3765 132 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 110634065 Common - DSBA oxidoreductase Meso_1713 94 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 110634884 Common - Substrate-binding region of ABC-type glycine betaine transport system Meso_2543 57 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 110635317 Common - transcriptional regulator, histidine utilization repressor, GntR family Meso_2988 119 COG2188 PhnF, Transcriptional regulators Transcription 110632545 Common - transcriptional regulator, LysR family Meso_0183 180 COG0583 LysR, Transcriptional regulator Transcription 110634296 Common - Mandelate racemase/muconate lactonizing enzyme-like Meso_1946 136 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 110632520 Common - 6-phosphogluconolactonase Meso_0158 119 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 110633074 Common - hypothetical protein Meso_0717 8 None None None 110633294 Common - Lytic transglycosylase, catalytic Meso_0940 156 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 110635953 Common - aldehyde dehydrogenase Meso_3627 222 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 110633010 Common - sugar transferase Meso_0653 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 110635688 Common - heme exporter protein CcmC Meso_3360 130 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 110632516 Nonpathogen - hypothetical protein Meso_0154 3 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 110633524 Common - ATP-dependent protease La Meso_1171 212 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 110634214 Common - ABC transporter related Meso_1864 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 110632469 Common - ATPase, FliI/YscN family Meso_0107 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 110636081 Common - amidohydrolase 2 Meso_3756 43 COG3618 COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 110635716 Common - intracellular septation protein A Meso_3388 92 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 110633606 Common - glucose-1-dehydrogenase Meso_1253 230 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110634728 Common - transcriptional regulator, LysR family Meso_2386 161 COG0583 LysR, Transcriptional regulator Transcription 110635524 Common - hypothetical protein Meso_3195 81 COG1692 COG1692, Uncharacterized protein conserved in bacteria Function unknown 110634463 Common - glycosyl transferase, family 25 Meso_2114 23 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 110634464 Common - hypothetical protein Meso_2115 10 None None None 110635340 Common - GCN5-related N-acetyltransferase Meso_3011 37 COG0456 RimI, Acetyltransferases General function prediction only 110636085 Nonpathogen - Carboxymuconolactone decarboxylase Meso_3760 1 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 110632613 Common - putative lipid kinase Meso_0252 108 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 110633466 Common - cationic amino acid ABC transporter, periplasmic binding protein Meso_1113 116 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 110633366 Common - HpcH/HpaI aldolase Meso_1012 115 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 110634770 Common - SirA-like Meso_2429 62 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 110633055 Common - F0F1 ATP synthase subunit B' Meso_0698 37 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 110635164 Common - polysaccharide deacetylase Meso_2831 64 COG3195 COG3195, Uncharacterized protein conserved in bacteria Function unknown 110634350 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase Meso_2000 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 110634374 Common - beta-lactamase Meso_2024 78 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 110633439 Common - exodeoxyribonuclease III Xth Meso_1085 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 110633397 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Meso_1043 26 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 110635396 Common - BolA-like protein Meso_3067 72 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 110634378 Common - 5,10-methylenetetrahydrofolate reductase Meso_2028 138 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 110634719 Common - transcriptional regulator, LysR family Meso_2377 157 COG0583 LysR, Transcriptional regulator Transcription 110633334 Common - 2-acylglycerophosphoethanolamine acyl transferase/acyl carrier protein synthetase Meso_0980 3 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 110635100 Common - hypothetical protein Meso_2767 24 None None None 110635938 Common - hypothetical protein Meso_3612 10 COG1661 COG1661, Predicted DNA-binding protein with PD1-like DNA-binding motif General function prediction only 110634261 Common - ABC transporter related Meso_1911 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 110632803 Common - 7-cyano-7-deazaguanine reductase Meso_0442 137 COG0780 COG0780, Enzyme related to GTP cyclohydrolase I General function prediction only 110632839 Common - inner-membrane translocator Meso_0478 148 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 110634444 Common carB carbamoyl phosphate synthase large subunit Meso_2095 232 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 110632850 Common - ABC transporter related Meso_0490 245 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 110632371 Common argD bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein Meso_0009 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 110633155 Common - transcriptional regulator, LysR family Meso_0798 190 COG0583 LysR, Transcriptional regulator Transcription 110634766 Common - cytochrome bd ubiquinol oxidase, subunit I Meso_2425 164 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 110634254 Common - PAS/PAC sensor hybrid histidine kinase Meso_1904 190 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 110632830 Common - major facilitator superfamily MFS_1 Meso_0469 205 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 110634513 Common - cytochrome c1 Meso_2164 52 COG2857 CYT1, Cytochrome c1 Energy production and conversion 110633079 Nonpathogen - hypothetical protein Meso_0722 2 None None None 110635017 Common - urease, beta subunit Meso_2683 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 110633192 Common - 3'(2'),5'-bisphosphate nucleotidase Meso_0835 166 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 110634083 Common - protein of unknown function DUF192 Meso_1732 92 COG1430 COG1430, Uncharacterized conserved protein Function unknown 110633492 Common nusB transcription antitermination protein NusB Meso_1139 185 COG0781 NusB, Transcription termination factor Transcription 110634902 Common - thiamine biosynthesis protein ThiC Meso_2561 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 110635466 Common - amidohydrolase Meso_3137 95 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 110636215 Common - Twin-arginine translocation pathway signal Meso_3891 64 COG3019 COG3019, Predicted metal-binding protein General function prediction only 110635506 Nonpathogen - hypothetical protein Meso_3177 1 None None None 110633400 Common - Cl- channel, voltage gated Meso_1046 162 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 110634585 Nonpathogen - cytochrome c, class I Meso_2237 9 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 110635592 Common - DNA polymerase III, alpha subunit Meso_3263 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 110635127 Common - hypothetical protein Meso_2794 14 COG3336 COG3336, Predicted membrane protein Function unknown 110632445 Nonpathogen - hypothetical protein Meso_0083 1 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 110633385 Common - NADH dehydrogenase subunit J Meso_1031 80 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 110635528 Common - HemY-like Meso_3199 26 COG3898 COG3898, Uncharacterized membrane-bound protein Function unknown 110633264 Nonpathogen - hypothetical protein Meso_0910 1 None None None 110633573 Nonpathogen - hypothetical protein Meso_1220 4 None None None 110633740 Common - putative membrane-associated zinc metalloprotease Meso_1387 211 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 110635760 Common - Helix-turn-helix, type 11 Meso_3432 85 COG2378 COG2378, Predicted transcriptional regulator Transcription 110635913 Common - short-chain dehydrogenase/reductase SDR Meso_3587 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110635060 Common - outer membrane lipoprotein Meso_2726 7 None None None 110632473 Common - export protein FliQ, family 3 Meso_0111 58 COG4794 EscS, Type III secretory pathway, component EscS Intracellular trafficking and secretion 110633526 Common - NADH:flavin oxidoreductase/NADH oxidase Meso_1173 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 110635657 Common - pyruvate carboxylase Meso_3329 240 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 110632823 Common - ABC transporter related Meso_0462 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 110636137 Nonpathogen - hypothetical protein Meso_3813 1 None None None 110633202 Common - 2-keto-3-deoxy-galactonokinase Meso_0845 40 COG3734 DgoK, 2-keto-3-deoxy-galactonokinase Carbohydrate transport and metabolism 110633409 Nonpathogen - hypothetical protein Meso_1055 1 COG2510 COG2510, Predicted membrane protein Function unknown 110635276 Common - Alcohol dehydrogenase, zinc-binding Meso_2947 197 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 110634756 Common - hypothetical protein Meso_2415 18 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 110633593 Nonpathogen - hypothetical protein Meso_1240 1 None None None 110634577 Common - protein of unknown function UPF0118 Meso_2229 172 COG0628 PerM, Predicted permease General function prediction only 110634014 Common - ribosomal protein L18 Meso_1662 217 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 110634481 Common - excinuclease ABC subunit B Meso_2132 228 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 110633779 Common - Rhodanese-like Meso_1426 146 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 110634505 Common - hypothetical protein Meso_2156 16 COG3189 COG3189, Uncharacterized conserved protein Function unknown 110636227 Common - aldo/keto reductase Meso_3903 201 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 110633232 Common - Fe-S metabolism associated SufE Meso_0875 97 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 110632828 Common - inositol-5-monophosphate dehydrogenase Meso_0467 242 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 110634748 Common - binding-protein-dependent transport systems inner membrane component Meso_2406 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110633633 Common - phosphoribosylformylglycinamidine synthase subunit PurS Meso_1280 87 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 110632462 Nonpathogen - hypothetical protein Meso_0100 1 None None None 110635453 Common - ABC transporter permease protein Meso_3124 41 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 110636333 Common - cytochrome P450 Meso_4009 84 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 110635174 Common - hypothetical protein Meso_2841 42 COG2319 COG2319, FOG: WD40 repeat General function prediction only 110633972 Common - putative TIM-barrel protein, nifR3 family Meso_1620 206 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 110635492 Common - sodium:dicarboxylate symporter Meso_3163 161 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 110635387 Common - cobalamin synthesis protein, P47K Meso_3058 128 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 110633161 Common - aldehyde dehydrogenase Meso_0804 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 110635793 Common - protein of unknown function UPF0057 Meso_3465 38 COG0401 COG0401, Uncharacterized homolog of Blt101 Function unknown 110634009 Common adk adenylate kinase Meso_1657 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 110634011 Common rplO 50S ribosomal protein L15 Meso_1659 203 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 110634828 Common - hypothetical protein Meso_2487 78 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 110634809 Common - GCN5-related N-acetyltransferase Meso_2468 73 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 110635557 Common - protein of unknown function DUF477 Meso_3228 48 COG3762 COG3762, Predicted membrane protein Function unknown 110635158 Common - beta-ketoadipyl CoA thiolase Meso_2825 169 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 110634313 Common - hypothetical protein Meso_1963 67 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 110632505 Common - protein of unknown function DUF1037 Meso_0143 19 COG4813 ThuA, Trehalose utilization protein Carbohydrate transport and metabolism 110635502 Common - Biopolymer transport protein ExbD/TolR Meso_3173 138 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 110633228 Common - transcriptional regulator, MucR family Meso_0871 34 COG4957 COG4957, Predicted transcriptional regulator Transcription 110635386 Common - peptidase S11, D-alanyl-D-alanine carboxypeptidase 1 Meso_3057 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 110635134 Common - TPR repeat Meso_2801 133 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 110632735 Common rpmH 50S ribosomal protein L34 Meso_0374 191 None None None 110635671 Common - lytic murein transglycosylase Meso_3343 103 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 110634205 Common - Twin-arginine translocation pathway signal Meso_1855 195 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 110635513 Common - elongation factor P Meso_3184 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 110634176 Common - elongation factor Tu Meso_1826 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 110634125 Common - TfoX-like Meso_1774 25 COG3070 TfoX, Regulator of competence-specific genes Transcription 110636040 Common - Twin-arginine translocation pathway signal Meso_3715 100 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 110633824 Common - peptidylprolyl isomerase, FKBP-type Meso_1471 167 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 110633316 Common - hypothetical protein Meso_0962 16 COG5451 COG5451, Predicted secreted protein Function unknown 110636023 Common - glycosyl transferase, family 2 Meso_3698 194 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 110633251 Common - Tetratricopeptide TPR_2 Meso_0897 47 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 110633350 Common - glycerophosphoryl diester phosphodiesterase Meso_0996 160 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 110635878 Nonpathogen - hypothetical protein Meso_3551 1 None None None 110636197 Common - protein of unknown function DUF305 Meso_3873 32 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 110632888 Common - transcriptional regulator, XRE family Meso_0528 8 None None None 110636130 Common - phage integrase Meso_3806 162 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 110636053 Common - binding-protein-dependent transport systems inner membrane component Meso_3728 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110633063 Common - 4-diphosphocytidyl-2C-methyl-D-erythritol kinase Meso_0706 191 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 110635151 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Meso_2818 230 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 110634938 Nonpathogen - PE-PGRS family protein Meso_2597 2 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 110632481 Common - type III secretion FHIPEP Meso_0119 127 COG4789 EscV, Type III secretory pathway, component EscV Intracellular trafficking and secretion 110634027 Common rplB 50S ribosomal protein L2 Meso_1675 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 110634272 Common - homoserine dehydrogenase Meso_1922 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 110632869 Common - type II secretion system protein E Meso_0509 143 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 110632815 Common - hypothetical protein Meso_0454 10 None None None 110632917 Common - protein of unknown function DUF156 Meso_0558 57 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 110635697 Common - protein of unknown function DUF107 Meso_3369 61 COG1030 NfeD, Membrane-bound serine protease (ClpP class) Posttranslational modification, protein turnover, chaperones 110635530 Common - uroporphyrinogen-III synthase Meso_3201 55 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 110633640 Common - peptidase S58, DmpA Meso_1287 50 COG3191 DmpA, L-aminopeptidase/D-esterase Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110633209 Common - death-on-curing family protein Meso_0852 62 COG3654 Doc, Prophage maintenance system killer protein General function prediction only 110636218 Common - Heavy metal transport/detoxification protein Meso_3894 30 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 110632575 Nonpathogen - hypothetical protein Meso_0213 1 None None None 110633567 Nonpathogen - hypothetical protein Meso_1214 1 None None None 110635588 Common tbpA thiamin transporter substrate binding subunit Meso_3259 56 COG4143 TbpA, ABC-type thiamine transport system, periplasmic component Coenzyme metabolism 110634839 Common - inner-membrane translocator Meso_2498 103 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 110633661 Common - 3-hydroxyisobutyrate dehydrogenase Meso_1308 177 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 110635665 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase Meso_3337 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 110632877 Common - Lytic transglycosylase, catalytic Meso_0517 147 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 110635533 Common - NAD-dependent glycerol-3-phosphate dehydrogenase-like Meso_3204 211 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 110635274 Common - Alpha/beta hydrolase fold-3 Meso_2945 135 COG0657 Aes, Esterase/lipase Lipid metabolism 110633628 Common - hypothetical protein Meso_1275 9 COG3543 COG3543, Uncharacterized conserved protein Function unknown 110634538 Nonpathogen - hypothetical protein Meso_2189 4 None None None 110633645 Common - protein of unknown function DUF182 Meso_1292 61 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 110632583 Common - hypothetical protein Meso_0222 2 None None None 110635544 Common - F0F1 ATP synthase subunit delta Meso_3215 111 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 110636108 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Meso_3783 174 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 110633329 Common - ABC transporter related Meso_0975 249 COG5265 ATM1, ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components Posttranslational modification, protein turnover, chaperones 110634931 Common - glycosyl transferase, group 1 Meso_2590 97 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110634279 Common - transcriptional regulator, LacI family Meso_1929 129 COG1609 PurR, Transcriptional regulators Transcription 110633477 Common - DNA topoisomerase IV subunit A Meso_1124 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 110634926 Common - glucose-methanol-choline oxidoreductase Meso_2585 82 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 110634167 Nonpathogen - hypothetical protein Meso_1817 1 None None None 110635803 Common - conserved hypothetical protein 701 Meso_3475 97 COG1981 COG1981, Predicted membrane protein Function unknown 110633655 Common - Exopolysaccharide synthesis, ExoD Meso_1302 41 COG3932 COG3932, Uncharacterized ABC-type transport system, permease components General function prediction only 110635161 Common - CMP/dCMP deaminase, zinc-binding Meso_2828 13 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 110633015 Common - glycosyl transferase, family 2 Meso_0658 23 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 110632479 Common - Flp pilus assembly protein secretin CpaC-like Meso_0117 82 COG4964 CpaC, Flp pilus assembly protein, secretin CpaC Intracellular trafficking and secretion 110635615 Common - Alcohol dehydrogenase, zinc-binding Meso_3287 172 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 110633103 Common - cytochrome c oxidase, subunit III Meso_0746 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 110636151 Common - hypothetical protein Meso_3827 9 None None None 110633246 Common - hypothetical protein Meso_0892 2 None None None 110633410 Common - NHL repeat Meso_1056 35 COG3391 COG3391, Uncharacterized conserved protein Function unknown 110633764 Common - protein of unknown function DUF922 Meso_1411 9 COG5661 COG5661, Predicted secreted Zn-dependent protease Posttranslational modification, protein turnover, chaperones 110635893 Common - endonuclease III Meso_3567 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 110635776 Common - isopropylmalate isomerase large subunit Meso_3448 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 110635349 Common - conserved repeat domain Meso_3020 8 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 110634245 Common - phage major capsid protein, HK97 family Meso_1895 61 COG4653 COG4653, Predicted phage phi-C31 gp36 major capsid-like protein General function prediction only 110634980 Common - Hydantoinase B/oxoprolinase Meso_2646 93 COG0146 HyuB, N-methylhydantoinase B/acetone carboxylase, alpha subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110634094 Common - tRNA delta(2)-isopentenylpyrophosphate transferase Meso_1743 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 110632603 Nonpathogen - hypothetical protein Meso_0242 1 None None None 110634283 Common - FAD dependent oxidoreductase Meso_1933 123 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 110635265 Nonpathogen - hypothetical protein Meso_2936 4 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 110636299 Common - ABC transporter related Meso_3975 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 110633356 Common - Patatin Meso_1002 122 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 110634116 Common - aminodeoxychorismate lyase Meso_1765 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 110632431 Common - AMP-dependent synthetase and ligase Meso_0069 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110635205 Common - putative cell-surface polysaccharide exporter protein, PST family Meso_2872 7 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 110633690 Nonpathogen - hypothetical protein Meso_1337 1 None None None 110636015 Common - protein of unknown function DUF1428 Meso_3690 39 COG5507 COG5507, Uncharacterized conserved protein Function unknown 110634132 Common - cysteine desulfurase activator complex subunit SufB Meso_1781 185 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 110633941 Common - class I diheme cytochrome c4 Meso_1589 61 COG2863 COG2863, Cytochrome c553 Energy production and conversion 110635418 Common - protein of unknown function DUF218 Meso_3089 31 COG1434 COG1434, Uncharacterized conserved protein Function unknown 110634971 Common - binding-protein-dependent transport systems inner membrane component Meso_2637 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110634721 Common - Amidase Meso_2379 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 110632765 Common - transcriptional regulator, LysR family Meso_0404 190 COG0583 LysR, Transcriptional regulator Transcription 110633272 Common - Carbamoyl-phosphate synthase L chain, ATP-binding Meso_0918 230 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 110636072 Common - Rhodanese-like Meso_3747 144 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 110635286 Common - L-carnitine dehydratase/bile acid-inducible protein F Meso_2957 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 110632941 Common - isoquinoline 1-oxidoreductase, beta subunit Meso_0583 20 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 110632849 Common - glycosyl transferase, family 2 Meso_0488 206 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 110634780 Nonpathogen - hypothetical protein Meso_2439 9 None None None 110635092 Common - ABC transporter related Meso_2758 245 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 110635976 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Meso_3651 37 COG3871 COG3871, Uncharacterized stress protein (general stress protein 26) General function prediction only 110636401 Common - putative PAS/PAC sensor protein Meso_4077 17 None None None 110632712 Common - periplasmic sensor signal transduction histidine kinase Meso_0351 210 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110633113 Common - protein of unknown function DUF156 Meso_0756 50 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 110634701 Common - transcriptional regulator, GntR family Meso_2357 116 COG1802 GntR, Transcriptional regulators Transcription 110636242 Common - phospholipid/glycerol acyltransferase Meso_3918 98 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 110636065 Common - binding-protein-dependent transport systems inner membrane component Meso_3740 220 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110634228 Common - hypothetical protein Meso_1878 6 None None None 110633215 Common - protein of unknown function DUF853, NPT hydrolase putative Meso_0858 77 COG0433 COG0433, Predicted ATPase General function prediction only 110632725 Common - FAD linked oxidase-like Meso_0364 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 110633514 Common - N-acetyl-gamma-glutamyl-phosphate reductase Meso_1161 197 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 110636161 Common - hypothetical protein Meso_3837 6 None None None 110634625 Common - transcriptional regulator, Crp/Fnr family Meso_2279 104 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 110635989 Common - protein of unknown function DUF1150 Meso_3664 16 COG5568 COG5568, Uncharacterized small protein Function unknown 110636264 Common - ferric uptake regulator, Fur family Meso_3940 148 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 110633786 Common - Antibiotic biosynthesis monooxygenase Meso_1433 38 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 110635705 Common - RNA-binding S4 Meso_3377 79 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 110633279 Common - hypothetical protein Meso_0925 5 None None None 110633170 Common - monooxygenase, FAD-binding Meso_0813 91 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 110632860 Common - conjugation TrbI-like protein Meso_0500 56 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 110635373 Common - transcriptional regulator, MarR family Meso_3044 52 COG1846 MarR, Transcriptional regulators Transcription 110635353 Common - HNH endonuclease Meso_3024 96 COG1403 McrA, Restriction endonuclease Defense mechanisms 110633086 Common - hypothetical protein Meso_0729 6 None None None 110632681 Common - septum site-determining protein MinD Meso_0320 133 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 110634954 Common - efflux transporter, RND family, MFP subunit Meso_2619 149 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 110632903 Common - DNA methylase N-4/N-6 Meso_0543 95 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 110633218 Common - manganese and iron superoxide dismutase Meso_0861 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 110634356 Common murC UDP-N-acetylmuramate--L-alanine ligase Meso_2006 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 110635749 Common - major facilitator superfamily MFS_1 Meso_3421 72 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 110633380 Common - NADH-quinone oxidoreductase, E subunit Meso_1026 154 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 110635033 Common - amino acid carrier protein Meso_2699 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 110634661 Common - Conjugal transfer protein TrbG/VirB9/CagX Meso_2316 53 COG3504 VirB9, Type IV secretory pathway, VirB9 components Intracellular trafficking and secretion 110632758 Common - MlrC-like Meso_0397 32 COG5476 COG5476, Uncharacterized conserved protein Function unknown 110634599 Nonpathogen - Cbb3-type cytochrome oxidase component Meso_2252 5 COG4736 CcoQ, Cbb3-type cytochrome oxidase, subunit 3 Posttranslational modification, protein turnover, chaperones 110633139 Common - Xylose isomerase-like TIM barrel Meso_0782 86 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 110635109 Nonpathogen - hypothetical protein Meso_2776 11 COG4641 COG4641, Uncharacterized protein conserved in bacteria Function unknown 110635960 Common - binding-protein-dependent transport systems inner membrane component Meso_3634 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110636049 Common - hypothetical protein Meso_3724 2 None None None 110636205 Nonpathogen - hypothetical protein Meso_3881 1 None None None 110634426 Common - Rhodanese-like Meso_2076 97 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 110636325 Common - type II secretion system protein Meso_4001 82 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 110633371 Common - glycine cleavage system protein H Meso_1017 185 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 110635050 Common - GCN5-related N-acetyltransferase Meso_2716 49 COG3153 COG3153, Predicted acetyltransferase General function prediction only 110636249 Common trmB tRNA (guanine-N(7))-methyltransferase Meso_3925 166 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 110634685 Common - protein of unknown function DUF736 Meso_2341 27 COG5489 COG5489, Uncharacterized conserved protein Function unknown 110635332 Common - protein of unknown function DUF1178 Meso_3003 47 COG5319 COG5319, Uncharacterized protein conserved in bacteria Function unknown 110634730 Common - hypothetical protein Meso_2388 8 None None None 110635407 Common - hypothetical protein Meso_3078 15 None None None 110633853 Common - MscS Mechanosensitive ion channel Meso_1500 167 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 110633893 Common - protein of unknown function DUF140 Meso_1540 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 110633733 Common - hypothetical protein Meso_1380 19 None None None 110633680 Common - glutathione-dependent formaldehyde-activating, GFA Meso_1327 58 COG3791 COG3791, Uncharacterized conserved protein Function unknown 110635982 Common deoA thymidine phosphorylase Meso_3657 121 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 110632380 Common - putative phage repressor Meso_0018 41 COG2932 COG2932, Predicted transcriptional regulator Transcription 110633451 Common - hypothetical protein Meso_1097 11 None None None 110636362 Common - ErfK/YbiS/YcfS/YnhG Meso_4038 81 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 110632920 Common - binding-protein-dependent transport systems inner membrane component Meso_0561 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110635568 Common - 2-octaprenyl-6-methoxyphenyl hydroxylase Meso_3239 136 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 110633387 Common - NADH dehydrogenase subunit L Meso_1033 209 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 110635480 Common - Alpha/beta hydrolase fold-3 Meso_3151 124 COG0657 Aes, Esterase/lipase Lipid metabolism 110636188 Common - protein of unknown function DUF6, transmembrane Meso_3864 117 COG2962 RarD, Predicted permeases General function prediction only 110635142 Common - hypothetical protein Meso_2809 8 None None None 110633790 Nonpathogen - biopolymer transport protein ExbD/TolR Meso_1437 1 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 110632798 Common - protein of unknown function DUF374 Meso_0437 39 COG2121 COG2121, Uncharacterized protein conserved in bacteria Function unknown 110633956 Common - transcriptional regulator, IclR family Meso_1604 122 COG1414 IclR, Transcriptional regulator Transcription 110636412 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Meso_4088 209 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 110632662 Common flgF flagellar basal body rod protein FlgF Meso_0301 125 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 110634694 Common - beta-ribofuranosylaminobenzene 5'-phosphate synthase family Meso_2350 23 COG1907 COG1907, Predicted archaeal sugar kinases General function prediction only 110632387 Common - Peptidoglycan-binding domain 1 Meso_0025 112 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 110635627 Common - protein of unknown function DUF112, transmembrane Meso_3299 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 110635004 Common - ABC transporter related Meso_2670 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 110633341 Common - replicative DNA helicase Meso_0987 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 110632619 Common - penicillin-binding protein 1C Meso_0258 200 COG4953 PbpC, Membrane carboxypeptidase/penicillin-binding protein PbpC Cell envelope biogenesis, outer membrane 110635325 Common - ATPase AAA-2 Meso_2996 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 110633531 Common - Ion transport 2 Meso_1178 40 COG1226 Kch, Kef-type K+ transport systems, predicted NAD-binding component Inorganic ion transport and metabolism 110634221 Common - N-formylglutamate amidohydrolase Meso_1871 43 COG3931 COG3931, Predicted N-formylglutamate amidohydrolase Amino acid transport and metabolism 110634294 Common - signal transduction histidine kinase Meso_1944 200 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 110633811 Common - phosphoglycolate phosphatase Meso_1458 201 COG0546 Gph, Predicted phosphatases General function prediction only 110633815 Common - phospho-2-dehydro-3-deoxyheptonate aldolase Meso_1462 73 COG3200 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 110634193 Common - FAD dependent oxidoreductase Meso_1843 115 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 110635446 Common - phosphate uptake regulator, PhoU Meso_3117 199 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 110635076 Nonpathogen - hypothetical protein Meso_2742 7 None None None 110632548 Common - Maf-like protein Meso_0186 199 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 110633676 Common - succinic semialdehyde dehydrogenase Meso_1323 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 110635769 Common - contains similarity to tropomyosin Meso_3441 14 None None None 110633485 Common - transcriptional regulator, MarR family Meso_1132 22 COG1846 MarR, Transcriptional regulators Transcription 110632594 Common - hypothetical protein Meso_0233 6 None None None 110634471 Common - protein of unknown function DUF21 Meso_2122 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 110634667 Common - conjugal transfer protein trbB Meso_2322 22 COG5268 TrbD, Type IV secretory pathway, TrbD component Cell motility and secretion / Intracellular trafficking and secretion 110635907 Common - UvrD/REP helicase Meso_3581 226 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 110633449 Common - binding-protein-dependent transport systems inner membrane component Meso_1095 143 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 110636284 Common - rare lipoprotein A Meso_3960 136 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 110633929 Nonpathogen - hypothetical protein Meso_1577 1 COG2433 COG2433, Uncharacterized conserved protein Function unknown 110636173 Common - TRAG protein Meso_3849 79 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 110634333 Common - hypothetical protein Meso_1983 30 COG4321 COG4321, Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis General function prediction only 110636145 Common - hypothetical protein Meso_3821 9 None None None 110635400 Common - cobalt chelatase, pCobT subunit Meso_3071 42 COG4547 CobT, Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase) Coenzyme metabolism 110636288 Common - transcriptional regulator, AsnC family Meso_3964 70 COG1522 Lrp, Transcriptional regulators Transcription 110635583 Common - N-formylglutamate amidohydrolase Meso_3254 40 COG3931 COG3931, Predicted N-formylglutamate amidohydrolase Amino acid transport and metabolism 110634652 Common - transcriptional regulator, IclR family Meso_2307 97 COG1414 IclR, Transcriptional regulator Transcription 110635641 Common - Uncharacterized protein UPF0065 Meso_3313 71 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 110636235 Common - hypothetical protein Meso_3911 50 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 110634349 Common - putative lipoprotein Meso_1999 127 COG4105 ComL, DNA uptake lipoprotein General function prediction only 110636320 Common - pilus assembly protein cpaB Meso_3996 49 COG3745 CpaB, Flp pilus assembly protein CpaB Intracellular trafficking and secretion 110632842 Common - Enoyl-CoA hydratase/isomerase Meso_0481 133 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 110633479 Common - Activator of Hsp90 ATPase-like Meso_1126 57 COG3832 COG3832, Uncharacterized conserved protein Function unknown 110636349 Common - protein of unknown function DUF59 Meso_4025 235 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 110632683 Common - glutathione S-transferase-like Meso_0322 97 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 110634363 Common - penicillin-binding protein, transpeptidase Meso_2013 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 110633598 Nonpathogen - hypothetical protein Meso_1245 2 None None None 110634633 Common - efflux transporter, RND family, MFP subunit Meso_2287 99 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 110635740 Common - phosphoribosylaminoimidazole carboxylase ATPase subunit Meso_3412 192 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 110635120 Nonpathogen - hypothetical protein Meso_2787 1 None None None 110636350 Common - Endonuclease/exonuclease/phosphatase Meso_4026 67 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 110633363 Common - hypothetical protein Meso_1009 6 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 110634327 Common - molybdopterin converting factor, subunit 1 Meso_1977 31 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 110635786 Common obgE GTPase ObgE Meso_3458 249 COG0536 Obg, Predicted GTPase General function prediction only 110634768 Common - formate dehydrogenase, alpha subunit Meso_2427 216 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 110635242 Common - hypothetical protein Meso_2912 2 None None None 110634947 Common - pentapeptide repeat Meso_2608 99 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 110633805 Common - nitrite reductase (NAD(P)H), small subunit Meso_1452 83 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 110632670 Common - Pyridoxal-5'-phosphate-dependent enzyme, beta subunit Meso_0309 216 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 110635751 Common - hypothetical protein Meso_3423 38 COG3786 COG3786, Uncharacterized protein conserved in bacteria Function unknown 110633354 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Meso_1000 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 110633423 Common - hypothetical protein Meso_1069 112 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 110633310 Common - GCN5-related N-acetyltransferase Meso_0956 130 COG0456 RimI, Acetyltransferases General function prediction only 110633833 Common - transcriptional regulator, XRE family Meso_1480 75 COG1396 HipB, Predicted transcriptional regulators Transcription 110634277 Nonpathogen - hypothetical protein Meso_1927 1 None None None 110635112 Common - NAD-dependent epimerase/dehydratase Meso_2779 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 110634450 Common - daunorubicin resistance ABC transporter ATPase subunit Meso_2101 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 110635750 Common - NAD-glutamate dehydrogenase Meso_3422 77 COG2902 COG2902, NAD-specific glutamate dehydrogenase Amino acid transport and metabolism 110636007 Common - short-chain dehydrogenase/reductase SDR Meso_3682 232 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 110634057 Common - protein of unknown function DUF502 Meso_1705 82 COG2928 COG2928, Uncharacterized conserved protein Function unknown 110633685 Common - ribonucleotide-diphosphate reductase subunit alpha Meso_1332 189 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 110636340 Common rph ribonuclease PH Meso_4016 186 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 110635055 Common modB molybdate ABC transporter permease protein Meso_2721 172 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 110635722 Common - AFG1-like ATPase Meso_3394 102 COG1485 COG1485, Predicted ATPase General function prediction only 110634412 Common - Twin-arginine translocation pathway signal Meso_2062 190 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 110633302 Common - holo-acyl-carrier-protein synthase Meso_0948 157 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 110635081 Common - alpha/beta hydrolase fold Meso_2747 64 COG2267 PldB, Lysophospholipase Lipid metabolism 110635425 Common - chaperonin Cpn10 Meso_3096 215 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 110633551 Common - hypothetical protein Meso_1198 2 None None None 110634270 Common - secretion protein HlyD Meso_1920 144 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 110635309 Common - binding-protein-dependent transport systems inner membrane component Meso_2980 145 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 110634898 Common - quinolinate synthetase Meso_2557 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 110634674 Common - transcriptional regulator, XRE family Meso_2329 49 COG1396 HipB, Predicted transcriptional regulators Transcription 110633458 Nonpathogen - hypothetical protein Meso_1104 1 None None None 110633173 Common - ABC transporter related Meso_0816 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 110636383 Common - peptide chain release factor 3 Meso_4059 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 110633032 Common - Mn2+-dependent serine/threonine protein kinase Meso_0675 6 COG3642 COG3642, Mn2+-dependent serine/threonine protein kinase Signal transduction mechanisms 110635255 Common - UbiD family decarboxylases Meso_2926 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 110632998 Common - hypothetical protein Meso_0641 19 COG3489 COG3489, Predicted periplasmic lipoprotein General function prediction only 110633920 Common - cation transporter Meso_1567 132 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 110633061 Common - Radical SAM Meso_0704 106 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 110633145 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Meso_0788 68 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 110636032 Common - inner-membrane translocator Meso_3707 148 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 110633887 Common - major facilitator superfamily MFS_1 Meso_1534 123 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 110635038 Nonpathogen - hypothetical protein Meso_2704 1 None None None 110633916 Common - polar amino acid ABC transporter, inner membrane subunit Meso_1563 172 COG4215 ArtQ, ABC-type arginine transport system, permease component Amino acid transport and metabolism 110635231 Common - fumarylacetoacetate (FAA) hydrolase Meso_2901 173 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 110632984 Common - hypothetical protein Meso_0627 28 COG5649 COG5649, Uncharacterized conserved protein Function unknown 110635410 Common - Methyltransferase type 11 Meso_3081 34 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 110633331 Nonpathogen - hypothetical protein Meso_0977 3 None None None 110634162 Common - beta-lactamase Meso_1811 58 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 110634882 Common - ABC transporter related Meso_2541 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 110633996 Common - ComEC/Rec2-related protein Meso_1644 112 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 110636104 Common - binding-protein-dependent transport systems inner membrane component Meso_3779 159 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 110636387 Common - hypothetical protein Meso_4063 69 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 110633851 Common - Endonuclease/exonuclease/phosphatase Meso_1498 13 COG2374 COG2374, Predicted extracellular nuclease General function prediction only 110633441 Nonpathogen - hypothetical protein Meso_1087 1 None None None 110635931 Common - diguanylate cyclase/phosphodiesterase Meso_3605 176 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 110634965 Common - NADH:flavin oxidoreductase/NADH oxidase Meso_2631 177 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 110635731 Common xerC site-specific tyrosine recombinase XerC Meso_3403 219 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 110632911 Common - transcriptional regulator, XRE family Meso_0551 28 COG1396 HipB, Predicted transcriptional regulators Transcription 110635222 Nonpathogen - hypothetical protein Meso_2889 1 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 110635393 Common - shikimate kinase Meso_3064 199 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 110632859 Common - hypothetical protein Meso_0499 23 COG5639 COG5639, Uncharacterized conserved small protein Function unknown 110636374 Common - Activator of Hsp90 ATPase-like Meso_4050 18 COG3832 COG3832, Uncharacterized conserved protein Function unknown 110633724 Common - peptidase S11, D-alanyl-D-alanine carboxypeptidase 1 Meso_1371 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 110634315 Common - CDP-alcohol phosphatidyltransferase Meso_1965 206 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 110635434 Common - protein of unknown function UPF0118 Meso_3105 176 COG0628 PerM, Predicted permease General function prediction only 110634109 Common - permease YjgP/YjgQ Meso_1758 97 COG0795 COG0795, Predicted permeases General function prediction only 110634075 Common - hypothetical protein Meso_1724 18 COG5388 COG5388, Uncharacterized protein conserved in bacteria Function unknown 110633181 Common - aspartate dehydrogenase Meso_0824 49 COG1712 COG1712, Predicted dinucleotide-utilizing enzyme General function prediction only 110635833 Common - acetyl-CoA acetyltransferase Meso_3505 107 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 110634590 Common - C4-dicarboxylate anaerobic carrier Meso_2242 41 COG1288 COG1288, Predicted membrane protein Function unknown 110634151 Common - peptidase M23B Meso_1800 189 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 110632408 Common - hypothetical protein Meso_0046 18 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 110634609 Common - Alcohol dehydrogenase GroES-like Meso_2263 197 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 110636058 Nonpathogen - hypothetical protein Meso_3733 1 None None None 110632401 Common - ABC transporter related Meso_0039 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 110632563 Nonpathogen - HNH endonuclease Meso_0201 1 None None None 110632396 Common - protein of unknown function DUF1611 Meso_0034 36 COG3367 COG3367, Uncharacterized conserved protein Function unknown 110634285 Common - spermidine/putrescine ABC transporter ATPase subunit Meso_1935 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 110634600 Common - cytochrome c oxidase, cbb3-type, subunit III Meso_2253 73 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 110632644 Common - chemotaxis protein Meso_0283 11 None None None 110634868 Common - Carboxymuconolactone decarboxylase Meso_2527 60 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 110635488 Common - adenylosuccinate synthetase Meso_3159 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 110636169 Common - conjugal transfer protein precursor Meso_3845 28 COG4959 TraF, Type IV secretory pathway, protease TraF Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 110633298 Common - protein of unknown function DUF88 Meso_0944 61 COG1432 COG1432, Uncharacterized conserved protein Function unknown 110634818 Common - cytochrome c oxidase, subunit III Meso_2477 158 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 110634200 Common - protein of unknown function DUF917 Meso_1850 34 COG3535 COG3535, Uncharacterized conserved protein Function unknown 110632659 Common flgB flagellar basal body rod protein FlgB Meso_0298 20 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 110633875 Nonpathogen - hypothetical protein Meso_1522 1 None None None 110634037 Common - hypothetical protein Meso_1685 7 None None None 110634783 Nonpathogen - hypothetical protein Meso_2442 8 None None None 110634149 Common - hypothetical protein Meso_1798 11 None None None 110632578 Nonpathogen - hypothetical protein Meso_0216 1 None None None 110635667 Common rpsP 30S ribosomal protein S16 Meso_3339 211 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 110632933 Common - Twin-arginine translocation pathway signal Meso_0575 157 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 110633977 Common - Transglycosylase-associated protein Meso_1625 10 COG2261 COG2261, Predicted membrane protein Function unknown 110632367 Common - ribulose-phosphate 3-epimerase Meso_0005 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 110632973 Common - peptidase, metallopeptidases Meso_0616 107 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 110633698 Common - GCN5-related N-acetyltransferase Meso_1345 11 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 110635494 Common - porin, opacity type Meso_3165 29 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 110635841 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Meso_3513 195 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 110635822 Common - hypothetical protein Meso_3494 15 None None None 110634459 Common - elongation factor G Meso_2110 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 110634985 Common - ABC transporter related Meso_2651 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 110635576 Nonpathogen - DoxX Meso_3247 2 COG2259 COG2259, Predicted membrane protein Function unknown 110634853 Common - MmgE/PrpD Meso_2512 60 COG2079 PrpD, Uncharacterized protein involved in propionate catabolism General function prediction only 110635298 Common - coenzyme A transferase Meso_2969 67 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 110636394 Common - hypothetical protein Meso_4070 3 None None None 110633880 Common - alpha,alpha-trehalose-phosphate synthase (UDP-forming) Meso_1527 97 COG0380 OtsA, Trehalose-6-phosphate synthase Carbohydrate transport and metabolism 110636163 Common - protein of unknown function DUF891 Meso_3839 33 COG4679 COG4679, Phage-related protein Function unknown 110636391 Common - TRAP transporter solute receptor, TAXI family Meso_4067 88 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 110632538 Common - hypothetical protein Meso_0176 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 110632974 Common - type I secretion membrane fusion protein, HlyD family Meso_0617 132 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 110634545 Common - bifunctional deaminase-reductase-like Meso_2196 66 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 110634047 Common - CDP-alcohol phosphatidyltransferase Meso_1695 29 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 110636371 Common - hypothetical protein Meso_4047 8 None None None 110633171 Common - binding-protein-dependent transport systems inner membrane component Meso_0814 197 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 110633872 Nonpathogen - hypothetical protein Meso_1519 3 None None None 110632696 Common - permease for cytosine/purines, uracil, thiamine, allantoin Meso_0335 53 COG1953 FUI1, Cytosine/uracil/thiamine/allantoin permeases Nucleotide transport and metabolism / Coenzyme metabolism 110633368 Common - hypothetical protein Meso_1014 15 COG5330 COG5330, Uncharacterized protein conserved in bacteria Function unknown 110635486 Common - hypothetical protein Meso_3157 14 None None None 110635789 Common - 50S ribosomal protein L21/unknown domain fusion protein Meso_3461 152 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 110634814 Nonpathogen - hypothetical protein Meso_2473 4 None None None 110634410 Common - binding-protein-dependent transport systems inner membrane component Meso_2060 198 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110632661 Common fliI flagellum-specific ATP synthase Meso_0300 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 110632702 Common - two component transcriptional regulator, LuxR family Meso_0341 174 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 110632585 Common - phage uncharacterized protein Meso_0224 34 COG5410 COG5410, Uncharacterized protein conserved in bacteria Function unknown 110635342 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Meso_3013 163 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 110634140 Common - major facilitator superfamily MFS_1 Meso_1789 128 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 110632565 Nonpathogen - hypothetical protein Meso_0203 2 None None None 110635227 Common - daunorubicin resistance ABC transporter ATPase subunit Meso_2894 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 110635091 Common - ABC-2 type transporter Meso_2757 61 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 110632862 Common - Conjugal transfer protein Meso_0502 34 COG3701 TrbF, Type IV secretory pathway, TrbF components Intracellular trafficking and secretion 110634536 Common - metallophosphoesterase Meso_2187 48 COG1409 Icc, Predicted phosphohydrolases General function prediction only 110635056 Common - molybdenum ABC transporter, periplasmic molybdate-binding protein Meso_2722 111 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 110635891 Common - Cupin 2, conserved barrel Meso_3565 30 COG3435 COG3435, Gentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 110632853 Common - uncharacterized domain 1 Meso_0493 60 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 110634670 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Meso_2325 50 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 110634147 Common - bifunctional preprotein translocase subunit SecD/SecF Meso_1796 221 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 110633275 Nonpathogen - hypothetical protein Meso_0921 1 None None None 110634790 Common - Twin-arginine translocation pathway signal Meso_2449 189 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 110636222 Common - hypothetical protein Meso_3898 30 COG0657 Aes, Esterase/lipase Lipid metabolism 110634900 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase Meso_2559 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 110633965 Common hfq RNA-binding protein Hfq Meso_1613 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 110635206 Common - hypothetical protein Meso_2873 5 None None None 110635812 Common fxsA FxsA Meso_3484 73 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 110635690 Common - periplasmic protein thiol--disulphide oxidoreductase DsbE Meso_3362 145 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 110633134 Common - UDP-glucose 4-epimerase Meso_0777 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 110634811 Common - transcriptional regulator, TrmB Meso_2470 115 COG1846 MarR, Transcriptional regulators Transcription 110632699 Common - TonB-dependent siderophore receptor Meso_0338 108 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 110635801 Common - protein of unknown function DUF255 Meso_3473 106 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 110633988 Common - triosephosphate isomerase Meso_1636 219 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 110636338 Common - putative deoxyribonucleotide triphosphate pyrophosphatase Meso_4014 231 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 110634417 Common - TonB family protein Meso_2067 34 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 110636055 Common - extracellular solute-binding protein, family 5 Meso_3730 177 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 110632519 Common - phosphogluconate dehydratase Meso_0157 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 110633460 Nonpathogen - hypothetical protein Meso_1106 1 None None None 110633841 Common - acetolactate synthase 3 catalytic subunit Meso_1488 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 110634406 Nonpathogen - Glyoxalase/bleomycin resistance protein/dioxygenase Meso_2056 8 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 110635240 Common - periplasmic sensor signal transduction histidine kinase Meso_2910 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110634051 Common - extracellular solute-binding protein, family 5 Meso_1699 182 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 110636388 Nonpathogen - hypothetical protein Meso_4064 1 None None None 110633006 Common - polysaccharide biosynthesis protein Meso_0649 77 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 110636035 Common - hypothetical protein Meso_3710 2 COG1359 COG1359, Uncharacterized conserved protein Function unknown 110634329 Common ndk nucleoside diphosphate kinase Meso_1979 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 110633348 Common - protein of unknown function DUF899, thioredoxin-like Meso_0994 29 COG4312 COG4312, Uncharacterized protein conserved in bacteria Function unknown 110632631 Nonpathogen - hypothetical protein Meso_0270 1 COG4889 COG4889, Predicted helicase General function prediction only 110635855 Common - hypothetical protein Meso_3527 15 COG5502 COG5502, Uncharacterized conserved protein Function unknown 110634192 Common - amidohydrolase 2 Meso_1842 40 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 110632389 Common - hypothetical protein Meso_0027 28 None None None 110635438 Common - two-component response regulator Meso_3109 117 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 110636398 Common - adenylate cyclase Meso_4074 47 COG2954 COG2954, Uncharacterized protein conserved in bacteria Function unknown 110635837 Common - hypothetical protein Meso_3509 2 COG3477 COG3477, Predicted periplasmic/secreted protein Function unknown 110634975 Common - amidohydrolase Meso_2641 202 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 110634746 Common - amidohydrolase Meso_2404 183 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 110632390 Common - metallophosphoesterase Meso_0028 46 COG1407 COG1407, Predicted ICC-like phosphoesterases General function prediction only 110633289 Common - hypothetical protein Meso_0935 9 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 110634073 Common - hypothetical protein Meso_1721 18 COG3811 COG3811, Uncharacterized protein conserved in bacteria Function unknown 110636135 Nonpathogen - hypothetical protein Meso_3811 1 None None None 110632404 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Meso_0042 204 COG0388 COG0388, Predicted amidohydrolase General function prediction only 110635428 Common - hypothetical protein Meso_3099 28 COG0400 COG0400, Predicted esterase General function prediction only 110636282 Common - binding-protein-dependent transport systems inner membrane component Meso_3958 155 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 110632391 Common - DEAD/H associated Meso_0029 215 COG1201 Lhr, Lhr-like helicases General function prediction only 110634202 Common - NADPH-dependent FMN reductase Meso_1852 65 COG0431 COG0431, Predicted flavoprotein General function prediction only 110634473 Common - transcriptional regulator, HxlR family Meso_2124 150 COG1733 COG1733, Predicted transcriptional regulators Transcription 110635435 Common - response regulator receiver protein Meso_3106 25 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 110634961 Common - major facilitator superfamily MFS_1 Meso_2627 116 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 110633456 Common - hypothetical protein Meso_1102 5 None None None 110634504 Common - ribose-phosphate pyrophosphokinase Meso_2155 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 110632503 Common - Na+/Pi-cotransporter Meso_0141 85 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 110633758 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase Meso_1405 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 110634726 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Meso_2384 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 110634873 Common - amidohydrolase Meso_2532 170 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 110632910 Common - hypothetical protein Meso_0550 13 None None None 110635825 Common - imidazole glycerol phosphate synthase subunit HisF Meso_3497 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 110633240 Common - penicillin-binding protein, 1A family Meso_0883 202 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 110634841 Common - beta-lactamase-like Meso_2500 94 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 110634763 Common - hypothetical protein Meso_2422 19 None None None 110634991 Common - MmgE/PrpD Meso_2657 58 COG2079 PrpD, Uncharacterized protein involved in propionate catabolism General function prediction only 110635695 Common - hypothetical protein Meso_3367 38 COG3750 COG3750, Uncharacterized protein conserved in bacteria Function unknown 110634260 Nonpathogen - protein of unknown function DUF982 Meso_1910 3 None None None 110634630 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Meso_2284 12 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 110636357 Common - PII uridylyl-transferase Meso_4033 125 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 110633516 Common rpsI 30S ribosomal protein S9 Meso_1163 248 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 110632650 Common fliP flagellar biosynthesis protein FliP Meso_0289 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 110632949 Common - sarcosine oxidase, delta subunit family Meso_0592 31 COG4311 SoxD, Sarcosine oxidase delta subunit Amino acid transport and metabolism 110633898 Common - nitrogen regulatory protein P-II Meso_1545 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 110633884 Common - peptidase S14, ClpP Meso_1531 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 110632988 Common - transcriptional regulator, ArsR family Meso_0631 103 COG0640 ArsR, Predicted transcriptional regulators Transcription 110633304 Common - ribonuclease III Meso_0950 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 110635083 Common - N-formylglutamate amidohydrolase Meso_2749 56 COG3741 HutG, N-formylglutamate amidohydrolase Amino acid transport and metabolism 110632840 Common - Extracellular ligand-binding receptor Meso_0479 123 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 110634870 Common - glycine betaine/L-proline ABC transporter, ATPase subunit Meso_2529 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 110635947 Common fumC fumarate hydratase Meso_3621 204 COG0114 FumC, Fumarase Energy production and conversion 110633918 Common - 6-phosphogluconate dehydrogenase, NAD-binding Meso_1565 195 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 110633066 Common - methyltransferase small Meso_0709 37 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 110632671 Common - transcriptional regulator, XRE family Meso_0310 47 COG3800 COG3800, Predicted transcriptional regulator General function prediction only 110632942 Common - autotransporter-associated beta strand repeat protein Meso_0585 86 None None None 110635724 Common sucC succinyl-CoA synthetase subunit beta Meso_3396 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 110634712 Common - spermidine/putrescine ABC transporter ATPase subunit Meso_2369 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 110634672 Common - TRAG protein Meso_2327 75 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 110634368 Common - N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD Meso_2018 111 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 110633429 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Meso_1075 229 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 110632794 Common - potassium efflux system protein Meso_0433 182 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 110636378 Common - hypothetical protein Meso_4054 2 None None None 110633599 Common - protein of unknown function DUF1696 Meso_1246 29 None None None 110633822 Common - glutathione S-transferase-like Meso_1469 90 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 110636102 Common - extracellular solute-binding protein, family 1 Meso_3777 97 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 110633474 Common - ribonuclease D Meso_1121 121 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 110636400 Common - histidine kinase Meso_4076 131 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110634056 Common - ATP-dependent DNA helicase RecG Meso_1704 210 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 110634953 Common - acriflavin resistance protein Meso_2618 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 110634794 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Meso_2453 13 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 110633716 Common - glutamyl-tRNA(Gln) amidotransferase, C subunit Meso_1363 172 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 110632543 Common - Stress responsive alpha-beta barrel Meso_0181 5 None None None 110635904 Common - protein of unknown function UPF0079 Meso_3578 195 COG3178 COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases General function prediction only 110635124 Common - cytochrome c oxidase, subunit I Meso_2791 175 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 110635445 Common - two component transcriptional regulator, winged helix family Meso_3116 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110634623 Nonpathogen - Calcium-binding EF-hand Meso_2277 4 None None None 110633945 Common - ABC transporter related Meso_1593 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 110635141 Common - hypothetical protein Meso_2808 16 None None None 110635988 Common - heat shock protein Hsp20 Meso_3663 64 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 110635420 Common - cell division ATP-binding protein FtsE Meso_3091 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 110634085 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Meso_1734 122 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 110633707 Common - DNA topoisomerase I Meso_1354 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 110634299 Common - extracellular solute-binding protein, family 5 Meso_1949 154 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 110634916 Common - transcriptional regulator, Crp/Fnr family Meso_2575 100 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 110634705 Common - putative NreB protein Meso_2362 7 None None None 110635542 Common - primosome assembly protein PriA Meso_3213 213 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 110634528 Common - ATPase associated with various cellular activities, AAA_3 Meso_2179 172 COG0714 COG0714, MoxR-like ATPases General function prediction only 110635736 Common - major facilitator superfamily MFS_1 Meso_3408 77 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 110635375 Common - Mandelate racemase/muconate lactonizing enzyme-like Meso_3046 121 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 110635618 Common - protein of unknown function DUF112, transmembrane Meso_3290 76 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 110635586 Common - TPR repeat Meso_3257 39 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 110636213 Common - putative signal-transduction protein with CBS domains Meso_3889 143 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 110632657 Common fliE flagellar hook-basal body protein FliE Meso_0296 22 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 110633859 Common - extracellular solute-binding protein, family 5 Meso_1506 201 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 110636238 Nonpathogen - hypothetical protein Meso_3914 1 None None None 110632906 Common - UvrD/REP helicase Meso_0546 80 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 110636306 Common - basic membrane lipoprotein Meso_3982 106 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 110635628 Common - Uncharacterized protein UPF0065 Meso_3300 74 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 110634458 Common - transcriptional regulator, MarR family with acetyltransferase activity Meso_2109 75 COG1846 MarR, Transcriptional regulators Transcription 110634907 Common - phosphomethylpyrimidine kinase Meso_2566 214 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 110635611 Common - L-carnitine dehydratase/bile acid-inducible protein F Meso_3283 115 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 110634297 Common - 5-dehydro-4-deoxyglucarate dehydratase Meso_1947 208 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 110634347 Common - DNA ligase, NAD-dependent Meso_1997 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 110633981 Common - pyruvate dehydrogenase subunit beta Meso_1629 214 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 110636231 Nonpathogen - hypothetical protein Meso_3907 4 None None None 110632426 Common - ABC transporter related Meso_0064 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 110633678 Common - bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase Meso_1325 220 COG4230 COG4230, Delta 1-pyrroline-5-carboxylate dehydrogenase Energy production and conversion 110634336 Nonpathogen - hypothetical protein Meso_1986 1 None None None 110635839 Common - conserved hypothetical membrane-anchored protein Meso_3511 3 None None None 110632847 Nonpathogen - hypothetical protein Meso_0486 5 None None None 110636420 Common - hypothetical protein Meso_4096 14 COG4964 CpaC, Flp pilus assembly protein, secretin CpaC Intracellular trafficking and secretion 110635099 Common - hypothetical protein Meso_2765 4 None None None 110634309 Common - hypothetical protein Meso_1959 20 COG5552 COG5552, Uncharacterized conserved protein Function unknown 110633041 Common - protein of unknown function DUF1330 Meso_0684 45 COG5470 COG5470, Uncharacterized conserved protein Function unknown 110633739 Common - phosphatidate cytidylyltransferase Meso_1386 209 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 110634857 Common - 6-phosphogluconate dehydrogenase, NAD-binding Meso_2516 183 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 110634511 Common - TrkA-C Meso_2162 131 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 110636245 Common - protein of unknown function UPF0054 Meso_3921 206 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 110635321 Nonpathogen - hypothetical protein Meso_2992 1 None None None 110633189 Common - DegT/DnrJ/EryC1/StrS aminotransferase Meso_0832 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 110634130 Common - FeS assembly protein SufD Meso_1779 175 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 110635248 Common - hypothetical protein Meso_2919 17 None None None 110632553 Common - hypothetical protein Meso_0191 21 None None None 110635267 Common - fumarylacetoacetate (FAA) hydrolase Meso_2938 177 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 110633937 Common - beta-lactamase-like Meso_1585 85 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 110636077 Common - enoyl-CoA hydratase Meso_3752 181 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 110634488 Nonpathogen - hypothetical protein Meso_2139 1 None None None 110634036 Nonpathogen - hypothetical protein Meso_1684 1 None None None 110635034 Common ligC ATP-dependent DNA ligase Meso_2700 104 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 110634637 Common - putative succinate dehydrogenase Meso_2292 62 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 110632760 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Meso_0399 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 110633323 Common - putative alpha-isopropylmalate/homocitrate synthase family transferase Meso_0969 212 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 110635256 Common - hypothetical protein Meso_2927 76 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 110635535 Common - protein of unknown function DUF55 Meso_3206 94 COG2947 COG2947, Uncharacterized conserved protein Function unknown 110634157 Common tatA twin argininte translocase protein A Meso_1806 43 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 110633732 Common - Endoribonuclease L-PSP Meso_1379 94 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 110636002 Common - tRNA/rRNA methyltransferase (SpoU) Meso_3677 212 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 110632928 Nonpathogen - hypothetical protein Meso_0569 4 None None None 110636417 Common - protease inhibitor, Kazal-type Meso_4093 4 None None None 110634229 Common - cell divisionFtsK/SpoIIIE Meso_1879 197 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 110633217 Common - haloacid dehalogenase, type II Meso_0860 62 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 110633575 Nonpathogen - hypothetical protein Meso_1222 1 None None None 110635564 Common - cell divisionFtsK/SpoIIIE Meso_3235 197 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 110633555 Nonpathogen - hypothetical protein Meso_1202 1 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 110633622 Common - glutamate racemase Meso_1269 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 110632459 Common - 2'-deoxycytidine 5'-triphosphate deaminase Meso_0097 48 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 110633438 Common - tRNA/rRNA methyltransferase (SpoU) Meso_1084 213 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 110633431 Common - Uncharacterized protein UPF0065 Meso_1077 75 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 110634334 Common - AsmA Meso_1984 21 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 110633695 Common - TadE-like Meso_1342 6 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 110634139 Common - peptidase M23B Meso_1788 187 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 110635549 Common - superoxide dismutase, copper/zinc binding Meso_3220 87 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 110632715 Common - DoxX Meso_0354 67 COG2259 COG2259, Predicted membrane protein Function unknown 110634785 Nonpathogen - hypothetical protein Meso_2444 10 None None None 110634596 Common - heavy metal translocating P-type ATPase Meso_2249 231 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 110635119 Nonpathogen - hypothetical protein Meso_2786 3 None None None 110634316 Common - phosphoribosylaminoimidazole synthetase Meso_1966 226 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 110633650 Common - hypothetical protein Meso_1297 6 None None None 110636202 Common - D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Meso_3878 65 COG3957 COG3957, Phosphoketolase Carbohydrate transport and metabolism 110635338 Common - hypothetical protein Meso_3009 2 None None None 110633744 Common - UDP-N-acetylglucosamine acyltransferase Meso_1391 156 COG1043 LpxA, Acyl- acyl carrier protein 110633249 Common - periplasmic sensor signal transduction histidine kinase Meso_0895 201 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110633487 Common glyA serine hydroxymethyltransferase Meso_1134 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 110633150 Common - Hemolysin-type calcium-binding region Meso_0793 84 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 110635958 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Meso_3632 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 110635184 Common - ABC-3 Meso_2851 126 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 110633794 Common - hemin transport system, hemin uptake protein Meso_1441 5 COG4256 HemP, Hemin uptake protein Inorganic ion transport and metabolism 110635291 Common - binding-protein-dependent transport systems inner membrane component Meso_2962 167 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 110632598 Common - hypothetical protein Meso_0237 7 None None None 110632776 Common - protein of unknown function DUF112, transmembrane Meso_0415 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 110635718 Common - MiaB-like tRNA modifying enzyme Meso_3390 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 110635440 Common - hypothetical protein Meso_3111 2 None None None 110634225 Common - protein of unknown function DUF1003 Meso_1875 14 COG4420 COG4420, Predicted membrane protein Function unknown 110632522 Common - FAD dependent oxidoreductase Meso_0160 118 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 110633106 Common - homoserine kinase Meso_0749 70 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 110634483 Common - cold-shock DNA-binding domain protein Meso_2134 178 COG1278 CspC, Cold shock proteins Transcription 110636115 Nonpathogen - hypothetical protein Meso_3790 2 None None None 110633021 Common trpA tryptophan synthase subunit alpha Meso_0664 216 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 110633114 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) Meso_0757 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 110632368 Common - carbon monoxide dehydrogenase subunit G Meso_0006 40 COG3427 COG3427, Uncharacterized conserved protein Function unknown 110634886 Common - urocanate hydratase Meso_2545 97 COG2987 HutU, Urocanate hydratase Amino acid transport and metabolism 110632955 Common - CheW protein Meso_0598 38 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 110632687 Common - putative transcriptional regulator, ArsR family Meso_0326 55 COG0640 ArsR, Predicted transcriptional regulators Transcription 110635888 Common - fumarylacetoacetate (FAA) hydrolase Meso_3562 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 110634430 Common - ABC transporter related Meso_2080 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 110635415 Common - hypothetical protein Meso_3086 9 COG4093 COG4093, Uncharacterized protein conserved in bacteria Function unknown 110635474 Common - putative fimbrial subunit PilA Meso_3145 6 None None None 110635673 Common - hypothetical protein Meso_3345 28 None None None 110636178 Common - ATPas Meso_3854 60 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 110634344 Common - peptidase M24 Meso_1994 224 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 110636262 Common - 3-oxoacyl-(acyl carrier protein) synthase I Meso_3938 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110633037 Common - chaperone protein DnaJ Meso_0680 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 110633700 Common - response regulator receiver protein Meso_1347 224 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 110635652 Common - inner-membrane translocator Meso_3324 139 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 110634409 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Meso_2059 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 110636033 Common - glucose-methanol-choline oxidoreductase Meso_3708 92 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 110634164 Common argS arginyl-tRNA synthetase Meso_1813 247 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110634521 Nonpathogen - hypothetical protein Meso_2172 1 None None None 110632437 Common - binding-protein-dependent transport systems inner membrane component Meso_0075 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110633234 Common - multi-sensor signal transduction histidine kinase Meso_0877 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110634602 Common - heavy metal translocating P-type ATPase Meso_2255 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 110634554 Common - hypothetical protein Meso_2205 23 COG5345 COG5345, Uncharacterized protein conserved in bacteria Function unknown 110633763 Common - ferredoxin Meso_1410 70 COG0633 Fdx, Ferredoxin Energy production and conversion 110633710 Common - hypothetical protein Meso_1357 168 COG0344 COG0344, Predicted membrane protein Function unknown 110633939 Common - proline racemase Meso_1587 47 COG3938 COG3938, Proline racemase Amino acid transport and metabolism 110633206 Nonpathogen - hypothetical protein Meso_0849 1 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 110635675 Common - transcriptional coactivator/pterin dehydratase Meso_3347 117 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 110636216 Common - transcriptional regulator, MerR family Meso_3892 144 COG0789 SoxR, Predicted transcriptional regulators Transcription 110634933 Common - lipopolysaccharide biosynthesis Meso_2592 99 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 110633672 Common - 3-oxoacyl-(acyl carrier protein) synthase II Meso_1319 180 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110635566 Common - nitrogen regulatory protein P-II Meso_3237 187 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 110632751 Common - contains weak similarity to transport protein (permease) Meso_0390 5 None None None 110635496 Common - ATP-dependent metalloprotease FtsH Meso_3167 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 110636117 Nonpathogen - hypothetical protein Meso_3792 1 None None None 110634765 Common - UV-endonuclease UvdE Meso_2424 24 COG4294 Uve, UV damage repair endonuclease DNA replication, recombination, and repair 110634550 Common - peptidase M50 Meso_2201 92 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 110633292 Common - hypothetical protein Meso_0938 8 None None None 110635516 Common - hypothetical protein Meso_3187 28 None None None 110633507 Common - sugar transferase Meso_1154 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 110633787 Nonpathogen - hypothetical protein Meso_1434 1 None None None 110635270 Common - aldo/keto reductase Meso_2941 199 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 110635865 Common - Cupin 2, conserved barrel Meso_3537 15 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 110635616 Common - Uncharacterized protein UPF0065 Meso_3288 71 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 110634944 Common - Pyrrolo-quinoline quinone Meso_2605 67 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 110636052 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Meso_3727 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 110635213 Common - glycosyl transferase, family 2 Meso_2880 88 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 110633500 Common ihfA integration host factor subunit alpha Meso_1147 196 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 110635644 Common - NUDIX hydrolase Meso_3316 100 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 110634775 Common - molybdopterin binding domain Meso_2434 152 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 110634123 Common ppnK inorganic polyphosphate/ATP-NAD kinase Meso_1772 232 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 110634920 Common - amino acid adenylation domain Meso_2579 204 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 110633076 Common - phosphoribosylamine--glycine ligase Meso_0719 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 110633636 Common - protein of unknown function DUF1234 Meso_1283 54 COG3545 COG3545, Predicted esterase of the alpha/beta hydrolase fold General function prediction only 110633846 Common - pyridoxal phosphate biosynthetic protein PdxJ Meso_1493 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 110632646 Common - hypothetical protein Meso_0285 9 None None None 110634025 Common rplV 50S ribosomal protein L22 Meso_1673 214 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 110634286 Common - putative spermidine/putrescine transport system substrate-binding protein Meso_1936 31 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 110635078 Common - ferredoxin-dependent glutamate synthase Meso_2744 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 110633637 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Meso_1284 40 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 110633013 Common - glycosyltransferase, SUCCINOGLYCAN BIOSYNTHESIS PROTEIN EXOL Meso_0656 7 None None None 110634713 Common - binding-protein-dependent transport systems inner membrane component Meso_2370 196 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 110635875 Common - major facilitator superfamily MFS_1 Meso_3547 131 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 110635152 Common - xylulokinase Meso_2819 182 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 110633709 Common - DNA protecting protein DprA Meso_1356 210 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 110635114 Common - hypothetical protein Meso_2781 12 None None None 110635009 Common - malto-oligosyltrehalose trehalohydrolase Meso_2675 175 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 110635684 Common - protein of unknown function DUF1223 Meso_3356 33 COG5429 COG5429, Uncharacterized secreted protein Function unknown 110632588 Nonpathogen - hypothetical protein Meso_0227 2 None None None 110633630 Common - phosphoribosylformylglycinamidine synthase II Meso_1277 234 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 110633979 Common - lipolytic enzyme, G-D-S-L Meso_1627 15 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 110634891 Nonpathogen - hypothetical protein Meso_2550 1 None None None 110635269 Common - Twin-arginine translocation pathway signal Meso_2940 36 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 110635454 Common - hypothetical protein Meso_3125 2 None None None 110632875 Common - TRAG protein Meso_0515 76 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 110635462 Common - binding-protein-dependent transport systems inner membrane component Meso_3133 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110635532 Common - O-sialoglycoprotein endopeptidase Meso_3203 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 110635991 Common - sigma 54 modulation protein/ribosomal protein S30EA Meso_3666 66 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 110635643 Common - protein of unknown function DUF112, transmembrane Meso_3315 76 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 110634929 Nonpathogen - hypothetical protein Meso_2588 1 None None None 110632468 Nonpathogen - hypothetical protein Meso_0106 1 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 110633702 Nonpathogen - hypothetical protein Meso_1349 1 None None None 110636191 Nonpathogen - hypothetical protein Meso_3867 1 None None None 110636147 Nonpathogen - hypothetical protein Meso_3823 1 None None None 110636024 Nonpathogen - hypothetical protein Meso_3699 5 None None None 110634744 Common - ABC transporter related Meso_2402 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 110635635 Common - transcriptional regulator, IclR family Meso_3307 121 COG1414 IclR, Transcriptional regulator Transcription 110632465 Nonpathogen - hypothetical protein Meso_0103 1 None None None 110634015 Common rplF 50S ribosomal protein L6 Meso_1663 239 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 110634160 Common - chromosome segregation and condensation protein ScpA Meso_1809 138 COG1354 COG1354, Uncharacterized conserved protein Function unknown 110636013 Common - homoserine dehydrogenase, NAD-binding Meso_3688 43 COG4091 COG4091, Predicted homoserine dehydrogenase Amino acid transport and metabolism 110635002 Common - protein of unknown function DUF894, DitE Meso_2668 134 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 110635133 Common rpsU 30S ribosomal protein S21 Meso_2800 39 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 110634822 Common - acyl-CoA dehydrogenase-like Meso_2481 160 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 110635581 Common - hypothetical protein Meso_3252 9 None None None 110634614 Nonpathogen - hypothetical protein Meso_2268 3 None None None 110635395 Common - protein of unknown function DUF21 Meso_3066 218 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 110632568 Nonpathogen - hypothetical protein Meso_0206 1 None None None 110636110 Common - Rhodanese-like Meso_3785 142 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 110633186 Common - peptidase M24 Meso_0829 6 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 110632771 Common - Xylose isomerase-like TIM barrel Meso_0410 26 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 110634914 Common - 4-hydroxybenzoate 3-monooxygenase Meso_2573 92 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 110635937 Common - molybdopterin oxidoreductase Meso_3611 161 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 110635790 Common - protein of unknown function DUF72 Meso_3462 110 COG1801 COG1801, Uncharacterized conserved protein Function unknown 110636304 Common - hypothetical protein Meso_3980 4 None None None 110633746 Common lpxB lipid-A-disaccharide synthase Meso_1393 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 110633930 Nonpathogen - conserved hypothetical signal peptide protein Meso_1578 11 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 110632366 Common - molybdopterin biosynthesis protein MoeB Meso_0004 215 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 110632482 Nonpathogen - hypothetical protein Meso_0120 1 None None None 110634517 Common - Lysine exporter protein (LYSE/YGGA) Meso_2168 116 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 110636140 Nonpathogen - hypothetical protein Meso_3816 5 None None None 110633725 Common - ATP-dependent Clp protease adaptor protein ClpS Meso_1372 121 COG2127 COG2127, Uncharacterized conserved protein Function unknown 110634654 Nonpathogen - hypothetical protein Meso_2309 1 None None None 110634219 Common - aldehyde dehydrogenase Meso_1869 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 110635998 Common - hypothetical protein Meso_3673 12 None None None 110634644 Common - regulatory protein, ArsR Meso_2299 9 COG1777 COG1777, Predicted transcriptional regulators Transcription 110633603 Common - nuclease (SNase-like) Meso_1250 8 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 110635540 Common - phospholipid/glycerol acyltransferase Meso_3211 39 COG3176 COG3176, Putative hemolysin General function prediction only 110635742 Common - protein of unknown function DUF1013 Meso_3414 41 COG3820 COG3820, Uncharacterized protein conserved in bacteria Function unknown 110634171 Common rplJ 50S ribosomal protein L10 Meso_1821 211 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 110634207 Common - binding-protein-dependent transport systems inner membrane component Meso_1857 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110635409 Common - beta-lactamase-like Meso_3080 196 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 110636321 Common - type II and III secretion system protein Meso_3997 136 COG4964 CpaC, Flp pilus assembly protein, secretin CpaC Intracellular trafficking and secretion 110635262 Common - transcriptional regulator, GntR family Meso_2933 126 COG1802 GntR, Transcriptional regulators Transcription 110633351 Common - binding-protein-dependent transport systems inner membrane component Meso_0997 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110633891 Common - metallophosphoesterase Meso_1538 61 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 110636103 Common - binding-protein-dependent transport systems inner membrane component Meso_3778 160 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 110633580 Nonpathogen - hypothetical protein Meso_1227 1 None None None 110633210 Common - transcriptional regulator/antitoxin, MazE Meso_0853 18 COG2336 MazE, Growth regulator Signal transduction mechanisms 110633587 Nonpathogen - hypothetical protein Meso_1234 2 None None None 110635651 Common - inner-membrane translocator Meso_3323 153 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 110632446 Common - acyltransferase 3 Meso_0084 16 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 110634353 Common - Polypeptide-transport-associated, FtsQ-type Meso_2003 84 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 110634994 Common - binding-protein-dependent transport systems inner membrane component Meso_2660 153 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 110636125 Nonpathogen - hypothetical protein Meso_3800 1 None None None 110635556 Common - protein of unknown function DUF477 Meso_3227 88 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 110635955 Common - cystathionine beta-lyase Meso_3629 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 110634683 Common - hypothetical protein Meso_2339 10 None None None 110636269 Common - DNA polymerase I Meso_3945 217 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 110635623 Nonpathogen - hypothetical protein Meso_3295 1 None None None 110632378 Common - hypothetical protein Meso_0016 15 None None None 110635277 Common - 3-hydroxyacyl-CoA dehydrogenase, NAD-binding Meso_2948 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 110633313 Common - glycine cleavage T protein (aminomethyl transferase) Meso_0959 123 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 110635571 Common - peptide methionine sulfoxide reductase Meso_3242 204 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 110633570 Common - phage protein GP20 Meso_1217 18 None None None 110634586 Common - UspA Meso_2238 52 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 110632913 Nonpathogen - hypothetical protein Meso_0553 1 None None None 110632609 Nonpathogen - hypothetical protein Meso_0248 1 None None None 110635479 Common - transcriptional regulator, AraC family Meso_3150 101 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 110634269 Common - drug resistance transporter, EmrB/QacA subfamily Meso_1919 227 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 110633259 Common - multi-sensor signal transduction histidine kinase Meso_0905 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110634570 Nonpathogen - response regulator receiver protein Meso_2221 2 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 110632570 Nonpathogen - hypothetical protein Meso_0208 1 None None None 110635367 Common - argininosuccinate lyase Meso_3038 231 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 110633520 Common - O-acetylhomoserine aminocarboxypropyltransferase Meso_1167 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 110636042 Nonpathogen - Xylose isomerase-like TIM barrel Meso_3717 5 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 110633442 Common - protein of unknown function DUF305 Meso_1088 21 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 110632822 Common - binding-protein-dependent transport systems inner membrane component Meso_0461 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110633402 Common - protein of unknown function DUF453 Meso_1048 55 COG2828 COG2828, Uncharacterized protein conserved in bacteria Function unknown 110635467 Common - Parallel beta-helix repeat Meso_3138 15 None None None 110636316 Common - phosphoadenosine phosphosulfate reductase Meso_3992 167 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 110633947 Common - binding-protein-dependent transport systems inner membrane component Meso_1595 155 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 110633053 Common - F0F1 ATP synthase subunit A Meso_0696 124 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 110634826 Common - hypothetical protein Meso_2485 39 COG0392 COG0392, Predicted integral membrane protein Function unknown 110635061 Common - homospermidine synthase Meso_2727 25 COG5310 COG5310, Homospermidine synthase Secondary metabolites biosynthesis, transport, and catabolism 110632411 Common - TRAP dicarboxylate transporter, DctM subunit Meso_0049 122 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 110633963 Common mazG nucleoside triphosphate pyrophosphohydrolase Meso_1611 158 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 110634827 Common - protein of unknown function DUF1311 Meso_2486 37 COG3755 COG3755, Uncharacterized protein conserved in bacteria Function unknown 110634262 Common - ABC-2 type transporter Meso_1912 177 COG1511 COG1511, Predicted membrane protein Function unknown 110635962 Common - FAD dependent oxidoreductase Meso_3636 141 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 110635176 Common - intradiol ring-cleavage dioxygenase Meso_2843 50 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 110634040 Common - dihydroxy-acid dehydratase Meso_1688 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 110633806 Common - molybdopterin oxidoreductase Meso_1453 186 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 110632616 Common - putative serine protein kinase, PrkA Meso_0255 69 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 110632962 Common - Flp/Fap pilin component Meso_0605 31 COG3847 Flp, Flp pilus assembly protein, pilin Flp Intracellular trafficking and secretion 110636327 Common - putative ferric uptake regulator, Fur family Meso_4003 96 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 110635843 Common - hypothetical protein Meso_3515 37 COG3652 COG3652, Predicted outer membrane protein Function unknown 110634178 Common - FAD dependent oxidoreductase Meso_1828 116 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 110635324 Common - protein of unknown function DUF419 Meso_2995 17 COG2315 MmcQ, Uncharacterized protein conserved in bacteria Function unknown 110635023 Nonpathogen - LmbE-like protein Meso_2689 5 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 110632470 Nonpathogen - hypothetical protein Meso_0108 1 None None None 110634063 Common - ribonuclease, Rne/Rng family Meso_1711 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 110634968 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Meso_2634 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 110633927 Common - conserved hypothetical/unknown signal peptide protein Meso_1575 11 None None None 110635905 Common - Nucleotidyl transferase Meso_3579 194 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 110635319 Nonpathogen - hypothetical protein Meso_2990 1 None None None 110636298 Common - aldehyde dehydrogenase Meso_3974 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 110633617 Common - PfkB Meso_1264 28 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 110635500 Common tolB translocation protein TolB Meso_3171 163 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 110634275 Common - poly(R)-hydroxyalkanoic acid synthase, class I Meso_1925 76 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 110635511 Common - thiamine-phosphate pyrophosphorylase Meso_3182 58 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 110635071 Common - KpsF/GutQ family protein Meso_2737 157 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 110632596 Common - hypothetical protein Meso_0235 5 None None None 110633197 Common - inner-membrane translocator Meso_0840 112 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 110633493 Common - major facilitator superfamily MFS_1 Meso_1140 49 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 110636220 Common - protein of unknown function DUF305 Meso_3896 21 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 110633199 Common - dihydroxy-acid dehydratase Meso_0842 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 110636181 Common - TrbL/VirB6 plasmid conjugal transfer protein Meso_3857 35 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 110634403 Common - alkylhydroperoxidase like protein, AhpD family Meso_2053 84 COG2128 COG2128, Uncharacterized conserved protein Function unknown 110634215 Common - extracellular solute-binding protein, family 1 Meso_1865 58 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 110632704 Common - Amidase Meso_0343 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 110636360 Common - UspA Meso_4036 26 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 110634443 Common - MltA-interacting MipA Meso_2094 28 COG3713 OmpV, Outer membrane protein V Cell envelope biogenesis, outer membrane 110633669 Nonpathogen - hypothetical protein Meso_1316 1 None None None 110635538 Common leuS leucyl-tRNA synthetase Meso_3209 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110635402 Common - hypothetical protein Meso_3073 50 COG1738 COG1738, Uncharacterized conserved protein Function unknown 110635068 Common - Peptidoglycan-binding domain 1 Meso_2734 46 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 110634246 Common - phage prohead protease, HK97 family Meso_1896 36 COG3740 COG3740, Phage head maturation protease General function prediction only 110633250 Common - hypothetical protein Meso_0896 17 COG4520 LipA, Surface antigen Cell envelope biogenesis, outer membrane 110636355 Common - DNA mismatch repair protein Meso_4031 201 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 110633169 Common - 4,5-dihydroxyphthalate decarboxylase Meso_0812 10 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 110633545 Nonpathogen - hypothetical protein Meso_1192 1 None None None 110635374 Common - FMN-dependent alpha-hydroxy acid dehydrogenase Meso_3045 112 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 110633467 Common - polar amino acid ABC transporter, inner membrane subunit Meso_1114 171 COG4597 BatB, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 110632835 Common - aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding Meso_0474 107 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 110634461 Common - thioredoxin reductase Meso_2112 245 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 110633538 Nonpathogen - HNH endonuclease Meso_1185 2 COG1403 McrA, Restriction endonuclease Defense mechanisms 110635216 Nonpathogen - hypothetical protein Meso_2883 12 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110635187 Common - transcriptional regulator, LacI family Meso_2854 126 COG1609 PurR, Transcriptional regulators Transcription 110633868 Common - conserved repeat domain Meso_1515 20 None None None 110633127 Nonpathogen - hypothetical protein Meso_0770 1 None None None 110633016 Common - UTP-glucose-1-phosphate uridylyltransferase Meso_0659 232 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 110635193 Common - transcriptional regulator, ArsR family Meso_2860 60 COG0640 ArsR, Predicted transcriptional regulators Transcription 110634758 Common - aldehyde dehydrogenase Meso_2417 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 110632730 Common - protein of unknown function DUF162 Meso_0369 54 COG1556 COG1556, Uncharacterized conserved protein Function unknown 110632524 Nonpathogen - response regulator receiver protein Meso_0162 1 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 110635167 Common - aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding Meso_2834 108 COG4631 XdhB, Xanthine dehydrogenase, molybdopterin-binding subunit B Nucleotide transport and metabolism 110635235 Common - protein of unknown function DUF1330 Meso_2905 20 COG5470 COG5470, Uncharacterized conserved protein Function unknown 110635343 Common - preprotein translocase subunit SecA Meso_3014 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 110636094 Common - short-chain dehydrogenase/reductase SDR Meso_3769 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 110632385 Common - acyl-CoA dehydrogenase-like Meso_0023 152 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 110636029 Common - short-chain dehydrogenase/reductase SDR Meso_3704 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110633162 Common - Carboxymuconolactone decarboxylase Meso_0805 20 None None None 110635753 Common - cyclic nucleotide-binding protein Meso_3425 35 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 110632881 Common - hypothetical protein Meso_0521 15 None None None 110632484 Common - hypothetical protein Meso_0122 2 None None None 110632497 Common - transport system permease protein Meso_0135 187 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 110634845 Common - 2-oxo-hepta-3-ene-1,7-dioic acid hydratase Meso_2504 64 COG3971 COG3971, 2-keto-4-pentenoate hydratase Secondary metabolites biosynthesis, transport, and catabolism 110633518 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Meso_1165 43 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 110632953 Common - two component transcriptional regulator, LuxR family Meso_0596 171 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 110632786 Common ileS isoleucyl-tRNA synthetase Meso_0425 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110635703 Common - acetoacetyl-CoA reductase Meso_3375 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110635719 Common dapF diaminopimelate epimerase Meso_3391 178 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 110632652 Common flgH flagellar basal body L-ring protein Meso_0291 100 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 110635936 Common - hypothetical protein Meso_3610 20 COG4530 COG4530, Uncharacterized protein conserved in bacteria Function unknown 110633096 Common - peptidase U62, modulator of DNA gyrase Meso_0739 169 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 110636291 Nonpathogen - hypothetical protein Meso_3967 5 None None None 110634093 Common - diguanylate cyclase Meso_1742 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 110633307 Common - major facilitator superfamily MFS_1 Meso_0953 131 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 110634267 Common rpsR 30S ribosomal protein S18 Meso_1917 215 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 110634068 Common - acetyl-CoA carboxylase biotin carboxylase subunit Meso_1716 236 COG0439 AccC, Biotin carboxylase Lipid metabolism 110634880 Common - molybdopterin oxidoreductase Meso_2539 174 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 110635088 Common - polysaccharide export protein Meso_2754 71 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 110634415 Common - transport system permease protein Meso_2065 149 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 110634395 Common - binding-protein-dependent transport systems inner membrane component Meso_2045 134 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 110633610 Common - hypothetical protein Meso_1257 2 None None None 110635459 Common - transcriptional regulator, GntR family Meso_3130 26 COG1725 COG1725, Predicted transcriptional regulators Transcription 110634703 Common - Uncharacterized protein putative amidase-like Meso_2360 76 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 110635197 Common - sugar isomerase (SIS) Meso_2864 208 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 110635757 Common - Polyprenyl synthetase Meso_3429 229 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 110635351 Common - hypothetical protein Meso_3022 27 COG4529 COG4529, Uncharacterized protein conserved in bacteria Function unknown 110632748 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase Meso_0387 142 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 110633561 Common - phage integrase Meso_1208 151 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 110634428 Common - binding-protein-dependent transport systems inner membrane component Meso_2078 160 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 110634731 Common - Uncharacterized protein UPF0065 Meso_2389 66 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 110635920 Common glk glucokinase Meso_3594 91 COG0837 Glk, Glucokinase Carbohydrate transport and metabolism 110632510 Common - YceI Meso_0148 54 COG2353 COG2353, Uncharacterized conserved protein Function unknown 110632622 Common - oxidoreductase-like Meso_0261 101 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 110636092 Common - transcriptional regulator, AraC family Meso_3767 114 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 110635102 Common - hypothetical protein Meso_2769 10 None None None 110632936 Common - transcriptional regulator, LysR family Meso_0578 186 COG0583 LysR, Transcriptional regulator Transcription 110636060 Nonpathogen - hypothetical protein Meso_3735 1 None None None 110635339 Common - mutator MutT protein Meso_3010 177 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 110634533 Common - GCN5-related N-acetyltransferase Meso_2184 95 COG3153 COG3153, Predicted acetyltransferase General function prediction only 110635796 Common - parB-like partition proteins Meso_3468 185 COG1475 Spo0J, Predicted transcriptional regulators Transcription 110632629 Common - hypothetical protein Meso_0268 11 None None None 110635835 Common - NAD-dependent epimerase/dehydratase Meso_3507 122 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 110635031 Common - Methyltransferase type 12 Meso_2697 79 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 110633751 Nonpathogen - hypothetical protein Meso_1398 13 COG5373 COG5373, Predicted membrane protein Function unknown 110634619 Common - nitroreductase Meso_2273 58 COG0778 NfnB, Nitroreductase Energy production and conversion 110634071 Common - NADH dehydrogenase Meso_1719 38 COG3761 COG3761, NADH:ubiquinone oxidoreductase 17.2 kD subunit Energy production and conversion 110635259 Common - Alcohol dehydrogenase, zinc-binding Meso_2930 208 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 110635328 Common prfA peptide chain release factor 1 Meso_2999 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 110632960 Common - type II secretion system protein Meso_0603 76 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 110632809 Common - aldo/keto reductase Meso_0448 185 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 110632379 Common lysK lysyl-tRNA synthetase Meso_0017 77 COG1384 LysS, Lysyl-tRNA synthetase (class I) Translation, ribosomal structure and biogenesis 110634058 Common - D-fructose-6-phosphate amidotransferase Meso_1706 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 110634475 Common - NAD-dependent epimerase/dehydratase Meso_2126 118 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 110635122 Nonpathogen - hypothetical protein Meso_2789 2 None None None 110636280 Common - ABC transporter related Meso_3956 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 110632448 Nonpathogen - hypothetical protein Meso_0086 1 None None None 110633178 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Meso_0821 44 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 110633268 Common - Endonuclease/exonuclease/phosphatase Meso_0914 30 COG3021 COG3021, Uncharacterized protein conserved in bacteria Function unknown 110632916 Common - DedA family protein Meso_0557 149 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 110635770 Common - protein of unknown function DUF710 Meso_3442 34 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 110635898 Common - periplasmic sensor signal transduction histidine kinase Meso_3572 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110633462 Nonpathogen - hypothetical protein Meso_1108 4 None None None 110633381 Common - NADH-quinone oxidoreductase, F subunit Meso_1027 165 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 110635927 Common - protein of unknown function DUF81 Meso_3601 21 None None None 110634872 Common proX glycine betaine transporter periplasmic subunit Meso_2531 35 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 110636211 Nonpathogen - hypothetical protein Meso_3887 10 None None None 110633952 Common - Methyltransferase type 12 Meso_1600 25 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 110633882 Common - HAD-superfamily hydrolase, subfamily IIB Meso_1529 89 COG1877 OtsB, Trehalose-6-phosphatase Carbohydrate transport and metabolism 110635422 Common - hypoxanthine phosphoribosyltransferase Meso_3093 152 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 110632673 Common - hypothetical protein Meso_0312 6 None None None 110633935 Common - methionyl-tRNA synthetase Meso_1583 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110633427 Common - Uncharacterized protein UPF0065 Meso_1073 71 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 110634710 Common - transcriptional regulator, IclR family Meso_2367 116 COG1414 IclR, Transcriptional regulator Transcription 110633896 Common - ABC-type uncharacterized transport system auxiliary component-like Meso_1543 24 COG3218 COG3218, ABC-type uncharacterized transport system, auxiliary component General function prediction only 110634342 Common - electron transport protein SCO1/SenC Meso_1992 109 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 110633839 Common - protein of unknown function DUF87 Meso_1486 70 COG0433 COG0433, Predicted ATPase General function prediction only 110635139 Common - alanine dehydrogenase/PNT-like Meso_2806 165 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 110633242 Common - plasmid maintenance system antidote protein, XRE family Meso_0885 58 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 110636366 Common - periplasmic sensor signal transduction histidine kinase Meso_4042 62 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110632531 Common - binding-protein-dependent transport systems inner membrane component Meso_0169 158 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 110634103 Common - hypothetical protein Meso_1752 15 None None None 110634053 Nonpathogen - hypothetical protein Meso_1701 1 None None None 110636100 Nonpathogen - hypothetical protein Meso_3775 1 None None None 110633529 Common - protein of unknown function DUF1206 Meso_1176 15 None None None 110635178 Common - transcriptional regulator, MarR family Meso_2845 120 COG1846 MarR, Transcriptional regulators Transcription 110632668 Common flhB flagellar biosynthesis protein FlhB Meso_0307 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 110636134 Common - DNA polymerase IV Meso_3810 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 110635484 Common - Transcriptional regulator-like Meso_3155 46 COG2808 PaiB, Transcriptional regulator Transcription 110632986 Common - hypothetical protein Meso_0629 9 None None None 110635726 Common kgd alpha-ketoglutarate decarboxylase Meso_3398 148 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 110634951 Common - ABC-2 type transporter Meso_2613 110 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 110634875 Nonpathogen - hypothetical protein Meso_2534 1 None None None 110633224 Common - putative monovalent cation/H+ antiporter subunit D Meso_0867 196 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 110634371 Common - hypothetical protein Meso_2021 12 COG5379 BtaA, S-adenosylmethionine:diacylglycerol 3-amino-3-carboxypropyl transferase Lipid metabolism 110633116 Common - peptidase M16-like Meso_0759 200 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 110633255 Common - protease Do Meso_0901 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 110633998 Common gltA type II citrate synthase Meso_1646 194 COG0372 GltA, Citrate synthase Energy production and conversion 110633415 Common - transcriptional regulator, GntR family Meso_1061 133 COG1802 GntR, Transcriptional regulators Transcription 110634860 Common - TRAP dicarboxylate transporter, DctP subunit Meso_2519 98 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 110636267 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Meso_3943 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 110633035 Common - oxidoreductase-like Meso_0678 174 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 110634543 Common - transcriptional regulator, HxlR family Meso_2194 123 COG1733 COG1733, Predicted transcriptional regulators Transcription 110632944 Common - Invasion associated locus B Meso_0587 6 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 110636122 Nonpathogen - hypothetical protein Meso_3797 1 None None None 110632977 Common - signal transduction histidine kinase Meso_0620 144 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 110635830 Common - phosphoenolpyruvate carboxykinase Meso_3502 98 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 110635636 Common - aminotransferase, class V Meso_3308 151 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 110636165 Common - putative transcriptional regulator Meso_3841 27 COG3311 AlpA, Predicted transcriptional regulator Transcription 110634782 Common - 4Fe-4S ferredoxin, iron-sulfur binding Meso_2441 75 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 110635807 Common - Maf-like protein Meso_3479 181 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 110632979 Common - transcriptional regulator, AraC family Meso_0622 140 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 110635972 Common - ABC transporter related Meso_3646 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 110634320 Common - protein of unknown function DUF519 Meso_1970 85 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 110635293 Common - ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components-like Meso_2964 48 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 110632655 Common - flagellar protein FlgA Meso_0294 26 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 110634799 Common - Methyltransferase type 11 Meso_2458 157 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 110634366 Common - hypothetical protein Meso_2016 27 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 110633911 Common moaA molybdenum cofactor biosynthesis protein A Meso_1558 199 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 110632972 Nonpathogen - hypothetical protein Meso_0615 2 None None None 110633830 Common - protein of unknown function DUF378 Meso_1477 10 COG2155 COG2155, Uncharacterized conserved protein Function unknown 110635058 Common hemH ferrochelatase Meso_2724 166 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 110634180 Common - NADPH-dependent FMN reductase Meso_1830 57 COG0431 COG0431, Predicted flavoprotein General function prediction only 110632638 Common flgL flagellar hook-associated protein FlgL Meso_0277 18 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 110634145 Common - Squalene/phytoene synthase Meso_1794 42 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 110634155 Common - Sec-independent protein translocase, TatC subunit Meso_1804 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 110634893 Common - glucose sorbosone dehydrogenase Meso_2552 123 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 110635733 Common - thiamine pyrophosphokinase Meso_3405 38 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 110634943 Common - Rieske (2Fe-2S) region Meso_2604 44 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 110635983 Common - phosphoribosyltransferase Meso_3658 164 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 110635857 Common - beta-lactamase-like Meso_3529 91 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 110633923 Common - hypothetical protein Meso_1570 14 COG3827 COG3827, Uncharacterized protein conserved in bacteria Function unknown 110634030 Common rplC 50S ribosomal protein L3 Meso_1678 217 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 110635782 Common - iojap-like protein Meso_3454 200 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 110634049 Common - hemimethylated DNA binding protein Meso_1697 45 COG3785 COG3785, Uncharacterized conserved protein Function unknown 110632486 Nonpathogen - hypothetical protein Meso_0124 1 None None None 110635940 Common - TRAP dicarboxylate transporter, DctP subunit Meso_3614 110 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 110634391 Common - transcriptional regulator, TetR family Meso_2041 78 COG1309 AcrR, Transcriptional regulator Transcription 110635814 Common - MltA Meso_3486 93 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 110632855 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein Meso_0495 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 110635157 Common - coenzyme A transferase Meso_2824 53 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 110634958 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Meso_2623 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 110632424 Common - major facilitator superfamily MFS_1 Meso_0062 116 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 110632992 Common - glycoside hydrolase, family 25 Meso_0635 46 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 110633717 Common - GCN5-related N-acetyltransferase Meso_1364 62 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 110632694 Common - permease for cytosine/purines, uracil, thiamine, allantoin Meso_0333 77 COG1953 FUI1, Cytosine/uracil/thiamine/allantoin permeases Nucleotide transport and metabolism / Coenzyme metabolism 110635498 Common - Tetratricopeptide TPR_2 Meso_3169 86 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 110635218 Common - 4-hydroxyphenylpyruvate dioxygenase Meso_2885 79 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 110635819 Common - GCN5-related N-acetyltransferase Meso_3491 28 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 110634669 Common - type II secretion system protein E Meso_2324 147 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 110634848 Common - 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase Meso_2507 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 110633557 Common - DnaB-like helicase-like Meso_1204 213 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 110635773 Common rplS 50S ribosomal protein L19 Meso_3445 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 110633975 Common - cyclase/dehydrase Meso_1623 101 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 110632802 Common mutL DNA mismatch repair protein Meso_0441 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 110633167 Common - transcriptional regulator, MarR family Meso_0810 75 COG1846 MarR, Transcriptional regulators Transcription 110633239 Common - protein of unknown function DUF1214 Meso_0882 18 COG5402 COG5402, Uncharacterized conserved protein Function unknown 110633026 Common - hypothetical protein Meso_0669 19 None None None 110636004 Common - Alcohol dehydrogenase GroES-like Meso_3679 106 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 110634773 Common mobA molybdopterin-guanine dinucleotide biosynthesis protein A Meso_2432 81 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 110632810 Common - Xylose isomerase-like TIM barrel Meso_0449 58 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 110633325 Common - conserved hypothetical protein 730 Meso_0971 143 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 110636037 Common - short-chain dehydrogenase/reductase SDR Meso_3712 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110634456 Common - aspartate aminotransferase Meso_2107 236 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 110636075 Common - L-carnitine dehydratase/bile acid-inducible protein F Meso_3750 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 110633346 Common - Tetratricopeptide TPR_4 Meso_0992 16 None None None 110633817 Common dnaG DNA primase Meso_1464 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 110633857 Common - binding-protein-dependent transport systems inner membrane component Meso_1504 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110635472 Nonpathogen - hypothetical protein Meso_3143 15 None None None 110632591 Nonpathogen - hypothetical protein Meso_0230 1 None None None 110635254 Common - aldehyde dehydrogenase Meso_2925 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 110636069 Common - Twin-arginine translocation pathway signal Meso_3744 40 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 110633132 Common - beta-lactamase-like Meso_0775 126 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 110632999 Common - protein of unknown function DUF1111 Meso_0642 50 COG3488 COG3488, Predicted thiol oxidoreductase Energy production and conversion 110633495 Common - SmpA/OmlA Meso_1142 26 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 110635562 Common - exodeoxyribonuclease III Xth Meso_3233 194 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 110636209 Common - Twin-arginine translocation pathway signal Meso_3885 184 COG0661 AarF, Predicted unusual protein kinase General function prediction only 110632754 Common fmt methionyl-tRNA formyltransferase Meso_0393 216 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 110634039 Common - Sel1-like repeat Meso_1687 79 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 110636260 Common - methyltransferase small Meso_3936 74 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 110636277 Common - peptidase M17, leucyl aminopeptidase-like Meso_3953 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 110633921 Common - protein-L-isoaspartate(D-aspartate) O-methyltransferase Meso_1568 157 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 110635117 Common - Alcohol dehydrogenase GroES-like Meso_2784 199 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 110633008 Common - O-antigen polymerase Meso_0651 16 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 110634099 Common - HflC protein Meso_1748 116 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 110632717 Common - protein of unknown function DUF81 Meso_0356 40 COG0730 COG0730, Predicted permeases General function prediction only 110634429 Common - ABC transporter, periplasmic substrate-binding protein Meso_2079 37 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 110633472 Common - polyphosphate kinase Meso_1119 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 110634318 Common - peptidase S10, serine carboxypeptidase Meso_1968 38 COG2939 COG2939, Carboxypeptidase C (cathepsin A) Amino acid transport and metabolism 110635547 Common - F0F1 ATP synthase subunit beta Meso_3218 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 110632534 Nonpathogen - phasin Meso_0172 9 COG5490 COG5490, Uncharacterized conserved protein Function unknown 110632762 Common - binding-protein-dependent transport systems inner membrane component Meso_0401 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110633906 Common - periplasmic sensor signal transduction histidine kinase Meso_1553 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110633489 Common - riboflavin biosynthesis protein RibD Meso_1136 229 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 110636200 Common - heavy metal translocating P-type ATPase Meso_3876 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 110633378 Common - NADH dehydrogenase subunit C Meso_1024 176 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 110634223 Common - zinc/iron permease Meso_1873 28 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 110636114 Common - Relaxase/mobilization nuclease domain Meso_3789 7 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 110633108 Common - Redoxin Meso_0751 82 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 110633730 Common - protein of unknown function DUF482 Meso_1377 81 COG3146 COG3146, Uncharacterized protein conserved in bacteria Function unknown 110634724 Common - binding-protein-dependent transport systems inner membrane component Meso_2382 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110632819 Common - OsmC-like protein Meso_0458 8 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 110634331 Common - transcriptional regulator, TetR family Meso_1981 83 COG1309 AcrR, Transcriptional regulator Transcription 110635886 Common - extracellular solute-binding protein, family 1 Meso_3559 72 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 110635845 Common - hypothetical protein Meso_3517 3 None None None 110634850 Common - Uncharacterized protein UPF0065 Meso_2509 69 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 110633693 Common - molybdopterin binding domain Meso_1340 165 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 110632909 Common - hypothetical protein Meso_0549 12 None None None 110634240 Nonpathogen - hypothetical protein Meso_1890 1 None None None 110634204 Common - transcriptional regulator, LuxR family Meso_1854 111 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 110632774 Common - NIPSNAP domain containing protein Meso_0413 10 None None None 110636074 Nonpathogen - hypothetical protein Meso_3749 1 None None None 110635995 Common - hypothetical protein Meso_3670 15 COG5375 COG5375, Uncharacterized protein conserved in bacteria Function unknown 110634834 Common - short-chain dehydrogenase/reductase SDR Meso_2493 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110633668 Common - lipid A biosynthesis lauroyl acyltransferase Meso_1315 109 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 110632864 Common - hypothetical protein Meso_0504 11 None None None 110635447 Common - phosphate ABC transporter, ATPase subunit Meso_3118 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 110633001 Common - protein of unknown function DUF900, hydrolase-like Meso_0644 26 COG4782 COG4782, Uncharacterized protein conserved in bacteria Function unknown 110634561 Common - response regulator receiver protein Meso_2212 194 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 110635902 Common - S-adenosyl-L-homocysteine hydrolase Meso_3576 177 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 110633444 Common - TRAP transporter solute receptor, TAXI family Meso_1090 67 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 110635442 Common - inner-membrane translocator Meso_3113 106 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 110635283 Common - L-carnitine dehydratase/bile acid-inducible protein F Meso_2954 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 110634510 Common - MaoC-like dehydratase Meso_2161 47 COG2030 MaoC, Acyl dehydratase Lipid metabolism 110636346 Common - CysZ-like protein Meso_4022 18 COG2981 CysZ, Uncharacterized protein involved in cysteine biosynthesis Amino acid transport and metabolism 110634749 Common - binding-protein-dependent transport systems inner membrane component Meso_2407 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110635377 Nonpathogen - hypothetical protein Meso_3048 1 None None None 110635869 Common - ABC transporter related Meso_3541 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 110633550 Nonpathogen - hypothetical protein Meso_1197 1 None None None 110634305 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Meso_1955 228 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 110634087 Nonpathogen - hypothetical protein Meso_1736 1 None None None 110634690 Common - putative DNA-binding protein Meso_2346 35 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 110633943 Common glpD glycerol-3-phosphate dehydrogenase Meso_1591 149 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 110634338 Common - UvrD/REP helicase Meso_1988 230 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 110633789 Nonpathogen - Biopolymer transport protein ExbD/TolR Meso_1436 4 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 110636403 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Meso_4079 206 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 110633290 Common - Lytic transglycosylase, catalytic Meso_0936 7 None None None 110633043 Common - transglutaminase-like cysteine peptidase, BTLCP Meso_0686 23 COG3672 COG3672, Predicted periplasmic protein Function unknown 110633263 Common - phage SPO1 DNA polymerase-related protein Meso_0909 155 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 110636418 Common - peptidase A24A, prepilin type IV Meso_4094 16 COG4960 CpaA, Flp pilus assembly protein, protease CpaA Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 110634993 Common - ABC transporter related Meso_2659 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 110632641 Common - two component transcriptional regulator, winged helix family Meso_0280 204 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110635787 Common - GCN5-related N-acetyltransferase Meso_3459 124 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 110632908 Common - Patatin Meso_0548 37 COG3621 COG3621, Patatin General function prediction only 110635413 Common - histidinol-phosphate aminotransferase Meso_3084 239 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 110634859 Common - TRAP dicarboxylate transporter, DctM subunit Meso_2518 136 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 110635097 Common - dTDP-4-dehydrorhamnose reductase Meso_2763 168 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 110634715 Common - Twin-arginine translocation pathway signal Meso_2372 61 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 110632477 Nonpathogen - hypothetical protein Meso_0115 1 None None None 110633454 Nonpathogen - hypothetical protein Meso_1100 1 None None None 110634733 Common - Citrate synthase Meso_2391 185 COG0372 GltA, Citrate synthase Energy production and conversion 110633396 Common - ABC transporter related Meso_1042 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 110633991 Common - Indole-3-glycerol phosphate synthase Meso_1639 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 110635018 Common ureC urease subunit alpha Meso_2684 96 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 110636293 Common - transcriptional regulator, GntR family Meso_3969 54 COG1802 GntR, Transcriptional regulators Transcription 110634787 Nonpathogen - hypothetical protein Meso_2446 7 COG5373 COG5373, Predicted membrane protein Function unknown 110635072 Common - hypothetical protein Meso_2738 18 COG5338 COG5338, Uncharacterized protein conserved in bacteria Function unknown 110633137 Common - sulphate transporter Meso_0780 161 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 110633959 Common - inner-membrane translocator Meso_1607 129 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 110636323 Common - response regulator receiver protein Meso_3999 104 COG4963 CpaE, Flp pilus assembly protein, ATPase CpaE Intracellular trafficking and secretion 110632845 Common - UDP-glucose/GDP-mannose dehydrogenase Meso_0484 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 110634290 Common - MaoC-like dehydratase Meso_1940 96 COG2030 MaoC, Acyl dehydratase Lipid metabolism 110632767 Common - FAD linked oxidase-like Meso_0406 199 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 110634307 Common - oxidoreductase-like Meso_1957 178 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 110635964 Common - hypothetical protein Meso_3638 31 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 110634789 Nonpathogen - Twin-arginine translocation pathway signal Meso_2448 3 None None None 110633088 Common - 3,4-dihydroxy-2-butanone 4-phosphate synthase Meso_0731 229 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 110635661 Common - efflux transporter, RND family, MFP subunit Meso_3333 156 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 110635000 Common - dihydroxy-acid dehydratase Meso_2666 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 110635745 Common - heat shock protein HtpX Meso_3417 192 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 110632555 Nonpathogen - hypothetical protein Meso_0193 1 None None None 110635246 Nonpathogen - hypothetical protein Meso_2916 1 None None None 110633737 Common frr ribosome recycling factor Meso_1384 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 110632607 Nonpathogen - hypothetical protein Meso_0246 2 None None None 110633404 Common - NHL repeat Meso_1050 37 COG3391 COG3391, Uncharacterized conserved protein Function unknown 110636153 Common - hypothetical protein Meso_3829 34 None None None 110633081 Common - pyridoxamine 5'-phosphate oxidase Meso_0724 133 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 110634515 Common - ubiquinol-cytochrome c reductase, iron-sulfur subunit Meso_2166 101 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 110635509 Common - protein of unknown function DUF1465 Meso_3180 18 COG5317 COG5317, Uncharacterized protein conserved in bacteria Function unknown 110633280 Common - hypothetical protein Meso_0926 6 None None None 110634563 Common - hypothetical protein Meso_2214 13 None None None 110634996 Common - 4,5-dihydroxyphthalate decarboxylase Meso_2662 10 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 110634066 Common - 3-dehydroquinate dehydratase Meso_1714 169 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 110634572 Common - multi-sensor signal transduction histidine kinase Meso_2223 222 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 110633949 Common - extracellular solute-binding protein, family 1 Meso_1597 35 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 110636309 Common - diguanylate cyclase/phosphodiesterase Meso_3985 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 110634455 Common - diguanylate phosphodiesterase Meso_2106 153 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 110635384 Nonpathogen - hypothetical protein Meso_3055 1 None None None 110632501 Common - protein of unknown function DUF201 Meso_0139 30 COG3919 COG3919, Predicted ATP-grasp enzyme General function prediction only 110634803 Common - transcriptional regulator, LysR family Meso_2462 182 COG0583 LysR, Transcriptional regulator Transcription 110635764 Common - fructose-bisphosphate aldolase, class-I Meso_3436 44 COG3588 COG3588, Fructose-1,6-bisphosphate aldolase Carbohydrate transport and metabolism 110636149 Nonpathogen - hypothetical protein Meso_3825 4 None None None 110633601 Common - protein of unknown function DUF159 Meso_1248 111 COG2135 COG2135, Uncharacterized conserved protein Function unknown 110635272 Common - transcriptional regulator, LysR family Meso_2943 185 COG0583 LysR, Transcriptional regulator Transcription 110633332 Common - phosphatidylserine decarboxylase Meso_0978 94 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 110634612 Common - Twin-arginine translocation pathway signal Meso_2266 153 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 110635554 Nonpathogen - hypothetical protein Meso_3225 1 None None None 110633577 Nonpathogen - hypothetical protein Meso_1224 4 None None None 110635609 Common - acyl-CoA dehydrogenase-like Meso_3281 169 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 110634001 Common - CrcB protein Meso_1649 182 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 110634128 Common - protein of unknown function DUF59 Meso_1777 146 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 110633666 Common - extracellular solute-binding protein, family 5 Meso_1313 210 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 110635084 Common - response regulator receiver protein Meso_2750 221 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 110634257 Common - Twin-arginine translocation pathway signal Meso_1907 114 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 110633051 Common - cell wall hydrolase, SleB Meso_0694 46 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 110634194 Common - protein of unknown function DUF112, transmembrane Meso_1844 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 110633629 Common - BolA-like protein Meso_1276 84 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 110635477 Common - polar amino acid ABC transporter, inner membrane subunit Meso_3148 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 110636318 Common - ribosomal protein S21 Meso_3994 40 None None None 110632817 Common - mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase Meso_0456 164 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 110633657 Nonpathogen - hypothetical protein Meso_1304 1 None None None 110632363 Common dnaA chromosomal replication initiation protein Meso_0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 110634922 Common - condensation domain Meso_2581 79 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 110634820 Common - cytochrome c oxidase subunit I Meso_2479 38 COG5473 COG5473, Predicted integral membrane protein Function unknown 110635279 Common - short-chain dehydrogenase/reductase SDR Meso_2950 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110634173 Common rplK 50S ribosomal protein L11 Meso_1823 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 110632572 Common - putative prophage repressor Meso_0210 11 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 110636123 Common - putative RNA methylase Meso_3798 30 COG1041 COG1041, Predicted DNA modification methylase DNA replication, recombination, and repair 110633652 Common - protein of unknown function DUF1194 Meso_1299 17 None None None 110634753 Common - Peptidoglycan-binding domain 1 Meso_2412 11 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 110635366 Common - Redoxin Meso_3037 130 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 110635743 Common - nuclease (SNase-like) Meso_3415 21 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 110635621 Common - Malate/L-lactate dehydrogenase Meso_3293 67 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 110632376 Common - glycosyl transferase, group 2 family protein Meso_0014 107 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 110635517 Common - hypothetical protein Meso_3188 153 COG1360 MotB, Flagellar motor protein Cell motility and secretion 110634322 Common - ribonuclease T2 Meso_1972 44 COG3719 Rna, Ribonuclease I Translation, ribosomal structure and biogenesis 110634210 Common - Uncharacterized protein putative amidase-like Meso_1860 83 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 110632726 Common - Uncharacterized membrane-anchored protein-like Meso_0365 41 COG4949 COG4949, Uncharacterized membrane-anchored protein conserved in bacteria Function unknown 110634061 Common - cell wall hydrolase/autolysin Meso_1709 177 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 110633362 Nonpathogen - hypothetical protein Meso_1008 2 None None None 110635305 Common - transcriptional regulator, GntR family Meso_2976 102 COG2188 PhnF, Transcriptional regulators Transcription 110633566 Common - phage-associated protein, HI1409 family Meso_1213 19 COG3567 COG3567, Uncharacterized protein conserved in bacteria Function unknown 110636311 Common - short-chain dehydrogenase/reductase SDR Meso_3987 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110632824 Common - ABC transporter related Meso_0463 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 110634018 Common rplE 50S ribosomal protein L5 Meso_1666 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 110632600 Common - hypothetical protein Meso_0239 4 None None None 110633609 Common - disulfide bond formation protein DsbB, putative Meso_1256 11 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 110636142 Common - hypothetical protein Meso_3818 5 None None None 110633212 Common - magnesium and cobalt transport protein CorA Meso_0855 145 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 110634824 Common - putative Sir2-like transcriptional silencer protein Meso_2483 30 None None None 110635911 Common - glutathione synthetase Meso_3585 126 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 110636044 Common - hypothetical protein Meso_3719 29 COG5441 COG5441, Uncharacterized conserved protein Function unknown 110633878 Common - short-chain dehydrogenase/reductase SDR Meso_1525 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110634581 Common - CBS domain containing membrane protein Meso_2233 155 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 110634355 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase Meso_2005 157 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 110634110 Common - Organic solvent tolerance protein Meso_1759 107 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 110633236 Common - protein of unknown function DUF1491 Meso_0879 21 COG5447 COG5447, Uncharacterized conserved protein Function unknown 110633801 Common - response regulator receiver and ANTAR domain protein Meso_1448 106 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 110636279 Common - Twin-arginine translocation pathway signal Meso_3955 127 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 110636359 Common - tryptophanyl-tRNA synthetase Meso_4035 228 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110634311 Common - putative ammonia monooxygenase Meso_1961 32 COG3180 AbrB, Putative ammonia monooxygenase General function prediction only 110633782 Common - transcriptional regulator, AsnC family Meso_1429 155 COG1522 Lrp, Transcriptional regulators Transcription 110634273 Common - aminotransferase Meso_1923 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 110636193 Common - hypothetical protein Meso_3869 20 None None None 110635215 Common - AMP-dependent synthetase and ligase Meso_2882 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110634697 Common - phosphoadenosine phosphosulfate reductase Meso_2353 43 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 110635694 Common - beta-lactamase-like Meso_3366 199 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 110635677 Common - 2'-5' RNA ligase Meso_3349 117 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 110635469 Common - hypothetical protein Meso_3140 49 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 110633204 Nonpathogen - Calcium-binding EF-hand Meso_0847 4 None None None 110633509 Common - polysaccharide export protein Meso_1156 112 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 110635702 Common - acetyl-CoA acetyltransferases Meso_3374 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 110635470 Common - hypothetical protein Meso_3141 9 None None None 110632873 Common - AAA ATPase, central region Meso_0513 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 110635986 Common - phosphonate metabolism protein PhnM Meso_3661 53 COG3454 COG3454, Metal-dependent hydrolase involved in phosphonate metabolism Inorganic ion transport and metabolism 110633765 Common - dihydropteroate synthase Meso_1412 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 110632435 Common - CDP-alcohol phosphatidyltransferase Meso_0073 31 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 110634688 Common - hypothetical protein Meso_2344 21 None None None 110634556 Common - pyridoxamine 5'-phosphate oxidase-related, FMN-binding Meso_2207 46 COG0748 HugZ, Putative heme iron utilization protein Inorganic ion transport and metabolism 110635545 Common - F0F1 ATP synthase subunit alpha Meso_3216 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 110635799 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA Meso_3471 192 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 110635884 Common - binding-protein-dependent transport systems inner membrane component Meso_3557 144 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 110634198 Common - transcriptional regulator, LysR family Meso_1848 175 COG0583 LysR, Transcriptional regulator Transcription 110635350 Common - peptidase M29, aminopeptidase II Meso_3021 56 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 110633768 Common - hypothetical protein Meso_1415 6 None None None 110633848 Common - transcriptional regulator, TetR family Meso_1495 10 COG1309 AcrR, Transcriptional regulator Transcription 110636156 Common - single-strand binding protein Meso_3832 194 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 110632648 Common - flagellin-like Meso_0287 94 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 110632508 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Meso_0146 113 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 110634678 Common - conjugal transfer protein precursor Meso_2333 31 COG4959 TraF, Type IV secretory pathway, protease TraF Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 110633480 Common - arginyl-tRNA-protein transferase Meso_1127 85 COG2935 COG2935, Putative arginyl-tRNA:protein arginylyltransferase Posttranslational modification, protein turnover, chaperones 110635646 Common - transcriptional regulator, LysR family Meso_3318 124 COG0583 LysR, Transcriptional regulator Transcription 110634541 Common - Activator of Hsp90 ATPase-like Meso_2192 69 COG3832 COG3832, Uncharacterized conserved protein Function unknown 110635867 Common - binding-protein-dependent transport systems inner membrane component Meso_3539 143 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 110635154 Nonpathogen - hypothetical protein Meso_2821 1 None None None 110634023 Common rplP 50S ribosomal protein L16 Meso_1671 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 110633773 Nonpathogen - hypothetical protein Meso_1420 1 None None None 110635670 Common - protein of unknown function DUF1236 Meso_3342 13 COG4991 COG4991, Uncharacterized protein with a bacterial SH3 domain homologue Function unknown 110633632 Common - phosphoribosylformylglycinamidine synthase subunit I Meso_1279 232 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 110632467 Nonpathogen - hypothetical protein Meso_0105 1 None None None 110633393 Common - protein of unknown function DUF1467 Meso_1039 16 COG5454 COG5454, Predicted secreted protein Function unknown 110633536 Nonpathogen - hypothetical protein Meso_1183 1 None None None 110633125 Common - chromosome segregation protein SMC Meso_0768 176 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 110633699 Common - hypothetical protein Meso_1346 21 None None None 110634007 Common - 30S ribosomal protein S11 Meso_1655 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 110633011 Nonpathogen - hypothetical protein Meso_0654 1 None None None 110634552 Common - GreA/GreB family elongation factor Meso_2203 13 COG0782 GreA, Transcription elongation factor Transcription 110633252 Common - cytochrome c-type biogenesis protein CcmE Meso_0898 96 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 110634288 Common - Enoyl-CoA hydratase/isomerase Meso_1938 181 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 110633421 Common - protein of unknown function DUF112, transmembrane Meso_1067 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 110632579 Nonpathogen - hypothetical protein Meso_0217 1 None None None 110634935 Common - glycosyl transferase, group 1 Meso_2594 135 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110633502 Common - Ku domain containing protein Meso_1149 63 COG1273 COG1273, Uncharacterized conserved protein Function unknown 110634594 Nonpathogen - hypothetical protein Meso_2247 4 None None None 110633973 Common ispDF bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein Meso_1621 196 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 110633644 Common - VWA containing CoxE-like Meso_1291 44 COG3552 CoxE, Protein containing von Willebrand factor type A (vWA) domain General function prediction only 110633649 Common - hypothetical protein Meso_1296 6 None None None 110633703 Common rpmG 50S ribosomal protein L33 Meso_1350 124 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 110634184 Common - binding-protein-dependent transport systems inner membrane component Meso_1834 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110635191 Common - ABC transporter related Meso_2858 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 110632938 Common - aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding Meso_0580 118 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 110634393 Common - allantoate amidohydrolase Meso_2043 84 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 110633563 Nonpathogen - hypothetical protein Meso_1210 1 None None None 110632969 Common - Tetratricopeptide TPR_2 Meso_0612 24 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 110634496 Common - export-related chaperone CsaA Meso_2147 152 COG0073 ARC1, EMAP domain General function prediction only 110636011 Common - alpha amylase, catalytic region Meso_3686 156 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 110635896 Common - PfkB Meso_3570 136 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 110632946 Common - acyl-CoA dehydrogenase-like Meso_0589 163 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 110633866 Common - conserved repeat domain Meso_1513 13 None None None 110634136 Common - tyrosyl-tRNA synthetase Meso_1785 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110633277 Common - Appr-1-p processing Meso_0923 116 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 110634909 Common - dihydrodipicolinate synthetase Meso_2568 226 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 110636096 Common - extracellular solute-binding protein, family 1 Meso_3771 103 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 110635063 Common - para-aminobenzoate synthase component I Meso_2729 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 110635104 Common - protein of unknown function DUF427 Meso_2771 31 COG2343 COG2343, Uncharacterized protein conserved in bacteria Function unknown 110635189 Common - binding-protein-dependent transport systems inner membrane component Meso_2856 154 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 110633309 Common - MscS Mechanosensitive ion channel Meso_0955 211 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 110633300 Common - (p)ppGpp synthetase I, SpoT/RelA Meso_0946 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 110633683 Nonpathogen - hypothetical protein Meso_1330 1 None None None 110634252 Common - phage integrase Meso_1902 13 None None None 110634989 Common - 3-hydroxyacyl-CoA dehydrogenase Meso_2655 136 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 110635345 Nonpathogen - hypothetical protein Meso_3016 1 None None None 110634250 Nonpathogen - hypothetical protein Meso_1900 1 None None None 110635264 Common - TRAP dicarboxylate transporter- DctP subunit Meso_2935 43 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 110635390 Common - acetyl-CoA carboxylase carboxyltransferase subunit alpha Meso_3061 189 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 110636172 Common - hypothetical protein Meso_3848 28 COG3843 VirD2, Type IV secretory pathway, VirD2 components (relaxase) Intracellular trafficking and secretion 110632526 Common - spermidine/putrescine ABC transporter ATPase subunit Meso_0164 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 110635727 Common - dihydrolipoamide acetyltransferase Meso_3399 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 110634091 Common - multi-sensor hybrid histidine kinase Meso_1740 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110632680 Common minC septum formation inhibitor Meso_0319 102 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 110636132 Common - hypothetical protein Meso_3808 58 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 110632784 Common - HAD-superfamily hydrolase, subfamily IIA Meso_0423 50 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 110635169 Common - transcriptional regulator, LysR family Meso_2836 176 COG0583 LysR, Transcriptional regulator Transcription 110634681 Common - Cobyrinic acid a,c-diamide synthase Meso_2336 200 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 110632951 Common - Sarcosine oxidase, gamma subunit Meso_0594 19 COG4583 COG4583, Sarcosine oxidase gamma subunit Amino acid transport and metabolism 110632897 Common - hypothetical protein Meso_0537 9 None None None 110636027 Common - transcriptional regulator, RpiR family Meso_3702 96 COG1737 RpiR, Transcriptional regulators Transcription 110632837 Common - ABC transporter related Meso_0476 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 110634491 Common - two component transcriptional regulator, winged helix family Meso_2142 213 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110633861 Common - glucosamine-6-phosphate isomerase Meso_1508 80 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 110636022 Common - UDP-N-acetylglucosamine 2-epimerase Meso_3697 158 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 110635190 Common - binding-protein-dependent transport systems inner membrane component Meso_2857 159 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 110633670 Common - Alcohol dehydrogenase, zinc-binding Meso_1317 205 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 110634385 Common - CBS domain containing membrane protein Meso_2035 191 COG0517 COG0517, FOG: CBS domain General function prediction only 110634941 Common - type I secretion membrane fusion protein, HlyD family Meso_2600 110 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 110635195 Common - Lysine exporter protein (LYSE/YGGA) Meso_2862 114 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 110635599 Common - protein of unknown function DUF343 Meso_3270 99 COG2835 COG2835, Uncharacterized conserved protein Function unknown 110633102 Common - cytochrome c oxidase assembly protein CtaG/Cox11 Meso_0745 68 COG3175 COX11, Cytochrome oxidase assembly factor Posttranslational modification, protein turnover, chaperones 110635934 Common - short-chain dehydrogenase/reductase SDR Meso_3608 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110632883 Common - replication protein A Meso_0523 32 COG5534 COG5534, Plasmid replication initiator protein DNA replication, recombination, and repair 110633432 Common - HpcH/HpaI aldolase Meso_1078 72 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 110634259 Common - cold-shock DNA-binding domain protein Meso_1909 175 COG1278 CspC, Cold shock proteins Transcription 110632807 Common - 3-oxoadipate enol-lactonase Meso_0446 187 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 110633719 Common - protein of unknown function DUF218 Meso_1366 91 COG1434 COG1434, Uncharacterized conserved protein Function unknown 110635600 Common - peptidase S16, lon-like Meso_3271 39 COG2802 COG2802, Uncharacterized protein, similar to the N-terminal domain of Lon protease General function prediction only 110632429 Common - extracellular solute-binding protein, family 5 Meso_0067 210 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 110632866 Common - ATPas Meso_0506 61 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 110635171 Common - guanine deaminase Meso_2838 159 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 110635049 Common - Orn/DAP/Arg decarboxylase 2 Meso_2715 216 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 110632620 Common - alpha-2-macroglobulin-like Meso_0259 80 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 110633953 Nonpathogen - alkylhydroperoxidase like protein, AhpD family Meso_1601 6 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 110633120 Common - DNA methylase N-4/N-6 Meso_0763 140 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 110635805 Nonpathogen - hypothetical protein Meso_3477 1 None None None 110633144 Common - TRAP dicarboxylate transporter, DctM subunit Meso_0787 134 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 110634265 Common - Methyltransferase type 11 Meso_1915 104 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 110633157 Common - transcriptional regulator, LuxR family Meso_0800 11 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 110636255 Common rbfA ribosome-binding factor A Meso_3931 101 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 110633188 Common - phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I Meso_0831 239 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 110632618 Common - hypothetical protein Meso_0257 71 COG2719 SpoVR, Uncharacterized conserved protein Function unknown 110632413 Common - DNA-binding transcriptional activator, 3HPP-binding Meso_0051 76 COG1414 IclR, Transcriptional regulator Transcription 110633712 Common pyrB aspartate carbamoyltransferase catalytic subunit Meso_1359 239 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 110635457 Nonpathogen - hypothetical protein Meso_3128 1 None None None 110634467 Common greA transcription elongation factor GreA Meso_2118 198 COG0782 GreA, Transcription elongation factor Transcription 110632739 Common - GTPase EngB Meso_0378 180 COG0218 COG0218, Predicted GTPase General function prediction only 110634911 Common - Zn-dependent hydrolases of the beta-lactamase fold-like Meso_2570 88 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 110632666 Common - flagellar motor switch protein FliN Meso_0305 124 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 110632918 Common - high-affinity nickel-transporter Meso_0559 27 COG2215 COG2215, ABC-type uncharacterized transport system, permease component General function prediction only 110633469 Common - ABC transporter related Meso_1116 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 110633534 Nonpathogen - hypothetical protein Meso_1181 2 None None None 110635040 Common - extracellular solute-binding protein, family 1 Meso_2706 70 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 110634431 Common - TrkA-C Meso_2081 117 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 110634476 Nonpathogen - glycosyl transferase, family 8 Meso_2127 5 COG5597 COG5597, Alpha-N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 110635965 Common - AMP-dependent synthetase and ligase Meso_3639 218 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110632890 Nonpathogen - hypothetical protein Meso_0530 10 None None None 110633582 Nonpathogen - hypothetical protein Meso_1229 2 None None None 110633925 Common - membrane protein involved in aromatic hydrocarbon degradation Meso_1572 28 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 110633002 Common - NUDIX hydrolase Meso_0645 20 COG4119 COG4119, Predicted NTP pyrophosphohydrolase DNA replication, recombination, and repair / General function prediction only 110632490 Common - transcriptional regulator, TetR family Meso_0128 71 COG1309 AcrR, Transcriptional regulator Transcription 110634468 Common - hypothetical protein Meso_2119 11 None None None 110632384 Common - acetyl-CoA acetyltransferase Meso_0022 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 110632415 Common - gentisate 1,2-dioxygenase Meso_0053 31 COG3435 COG3435, Gentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 110635712 Common - aspartate-semialdehyde dehydrogenase Meso_3384 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 110634422 Nonpathogen - hypothetical protein Meso_2072 1 None None None 110633808 Common - methionine aminopeptidase Meso_1455 244 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 110634217 Common - GntR-like Meso_1867 80 COG2186 FadR, Transcriptional regulators Transcription 110634646 Common - hypothetical protein Meso_2301 31 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 110634233 Common - phage minor tail Meso_1883 9 COG4718 COG4718, Phage-related protein Function unknown 110634977 Common - aminotransferase, class I and II Meso_2643 236 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 110632512 Common - inosine guanosine and xanthosine phosphorylase family Meso_0150 111 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 110632457 Common - hypothetical protein Meso_0095 13 None None None 110634028 Common rplW 50S ribosomal protein L23 Meso_1676 228 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 110635064 Common - oligoendopeptidase, pepF/M3 family Meso_2730 89 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 110632741 Common - acetylglutamate kinase Meso_0380 221 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 110633109 Common - hypothetical protein Meso_0752 42 COG4233 COG4233, Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis Posttranslational modification, protein turnover, chaperones / Energy production and conversion 110633547 Nonpathogen - hypothetical protein Meso_1194 3 None None None 110633195 Common - putative sugar uptake ABC transporter periplasmic solute-binding protein precursor Meso_0838 84 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 110635755 Nonpathogen - hypothetical protein Meso_3427 1 None None None 110633078 Common - hypothetical protein Meso_0721 17 COG5486 COG5486, Predicted metal-binding integral membrane protein Function unknown 110634244 Nonpathogen - hypothetical protein Meso_1894 2 None None None 110635312 Common - urocanate hydratase Meso_2983 97 COG2987 HutU, Urocanate hydratase Amino acid transport and metabolism 110636196 Common - hypothetical protein Meso_3872 5 None None None 110632561 Nonpathogen - hypothetical protein Meso_0199 1 None None None 110636139 Common - hypothetical protein Meso_3815 19 None None None 110634441 Common - transcriptional regulator, HxlR family Meso_2092 126 COG1733 COG1733, Predicted transcriptional regulators Transcription 110633540 Common - hypothetical protein Meso_1187 7 None None None 110635397 Common - heat shock protein DnaJ-like Meso_3068 74 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 110634021 Common rpsQ 30S ribosomal protein S17 Meso_1669 230 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 110633098 Common - cytochrome c oxidase, subunit II Meso_0741 159 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 110632542 Common - signal transduction histidine kinase Meso_0180 62 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 110635013 Common - alpha amylase, catalytic region Meso_2679 116 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 110635973 Nonpathogen - hypothetical protein Meso_3648 1 None None None 110633058 Common - transcriptional regulator, TetR family Meso_0701 25 COG1309 AcrR, Transcriptional regulator Transcription 110635452 Common - ABC transporter related Meso_3123 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 110634199 Common - protein of unknown function DUF917 Meso_1849 35 COG3535 COG3535, Uncharacterized conserved protein Function unknown 110633085 Common - Phosphoglycerate mutase Meso_0728 175 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 110633511 Common - hypothetical protein Meso_1158 10 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 110632549 Common infA translation initiation factor IF-1 Meso_0187 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 110634832 Common - TRAP dicarboxylate transporter, DctM subunit Meso_2491 120 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 110636162 Common - hypothetical protein Meso_3838 15 COG5419 COG5419, Uncharacterized conserved protein Function unknown 110633704 Common - NUDIX hydrolase Meso_1351 43 None None None 110633446 Common - hypothetical protein Meso_1092 13 COG5589 COG5589, Uncharacterized conserved protein Function unknown 110633498 Common - fatty acid/phospholipid synthesis protein Meso_1145 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 110633870 Common - hypothetical protein Meso_1517 6 None None None 110634348 Common - DNA repair protein RecN Meso_1998 198 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 110633028 Common infC translation initiation factor IF-3 Meso_0671 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 110632764 Common - Twin-arginine translocation pathway signal Meso_0403 201 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 110635313 Common - N-formylglutamate amidohydrolase Meso_2984 57 COG3741 HutG, N-formylglutamate amidohydrolase Amino acid transport and metabolism 110632422 Common - molybdopterin dehydrogenase, FAD-binding Meso_0060 85 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 110634303 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Meso_1953 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 110636343 Common - GrpE protein Meso_4019 228 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 110634709 Common - argininosuccinate lyase Meso_2366 217 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 110632364 Common - DNA polymerase III subunit beta Meso_0002 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 110635847 Nonpathogen - putative lipoprotein Meso_3519 4 None None None 110633778 Common - secretory lipase Meso_1425 26 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 110634364 Common - hypothetical protein Meso_2014 15 COG5462 COG5462, Predicted secreted (periplasmic) protein Function unknown 110635463 Common - Succinylglutamate desuccinylase/aspartoacylase Meso_3134 52 COG3608 COG3608, Predicted deacylase General function prediction only 110636187 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Meso_3863 11 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 110634591 Common - nitrite reductase, copper-containing Meso_2243 65 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 110633584 Common - hypothetical protein Meso_1231 4 None None None 110632843 Common - fumarate reductase/succinate dehydrogenase flavoprotein-like Meso_0482 62 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 110634293 Common - MCP methyltransferase, CheR-type Meso_1943 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 110634784 Nonpathogen - hypothetical protein Meso_2443 8 None None None 110635128 Common - efflux transporter, RND family, MFP subunit Meso_2795 154 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 110634890 Common - transcriptional regulator, LysR family Meso_2549 156 COG0583 LysR, Transcriptional regulator Transcription 110634750 Common - extracellular solute-binding protein, family 5 Meso_2408 217 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 110632557 Nonpathogen - hypothetical protein Meso_0195 1 None None None 110632478 Nonpathogen - hypothetical protein Meso_0116 1 None None None 110632940 Common - Twin-arginine translocation pathway signal Meso_0582 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 110633736 Common pyrH uridylate kinase Meso_1383 238 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 110634854 Common - carboxyvinyl-carboxyphosphonate phosphorylmutase Meso_2513 134 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 110636384 Common - transcriptional regulator, ArsR family Meso_4060 101 COG0640 ArsR, Predicted transcriptional regulators Transcription 110632799 Common - 3-deoxy-D-manno-octulosonic-acid transferase Meso_0438 125 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 110634341 Common - antibiotic acetyltransferase Meso_1991 184 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 110632947 Common - transcriptional regulator, AraC family Meso_0590 137 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 110634664 Common - hypothetical protein Meso_2319 9 None None None 110633019 Common - FolC bifunctional protein Meso_0662 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 110633135 Common - sugar transferase Meso_0778 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 110632983 Common - catalase/peroxidase HPI Meso_0626 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 110636234 Common - Carboxymuconolactone decarboxylase Meso_3910 88 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 110636105 Common - ABC transporter related Meso_3780 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 110633829 Common pyrE orotate phosphoribosyltransferase Meso_1476 126 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 110635411 Common - 2-nitropropane dioxygenase, NPD Meso_3082 107 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 110633267 Common - acyltransferase 3 Meso_0913 63 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 110632921 Common - binding-protein-dependent transport systems inner membrane component Meso_0562 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110632434 Common apaG ApaG Meso_0072 89 COG2967 ApaG, Uncharacterized protein affecting Mg2+/Co2+ transport Inorganic ion transport and metabolism 110635567 Common - acyl-CoA thioesterase II Meso_3238 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 110636411 Common - prephenate dehydratase Meso_4087 213 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 110634887 Common - allantoate amidohydrolase Meso_2546 85 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 110635419 Common - protein of unknown function DUF214 Meso_3090 37 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 110634248 Common - phage portal protein, HK97 family Meso_1898 66 COG4695 COG4695, Phage-related protein Function unknown 110634222 Common - transcriptional regulator, RpiR family Meso_1872 89 COG1737 RpiR, Transcriptional regulators Transcription 110633942 Common - transcriptional regulator, DeoR family Meso_1590 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 110634354 Common ddl D-alanine--D-alanine ligase Meso_2004 212 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 110635968 Common - binding-protein-dependent transport systems inner membrane component Meso_3642 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110635326 Common - hypothetical protein Meso_2997 31 None None None 110635028 Common - Myo-inositol-1-phosphate synthase Meso_2694 58 COG1260 INO1, Myo-inositol-1-phosphate synthase Lipid metabolism 110635630 Common - transcriptional regulator, LysR family Meso_3302 177 COG0583 LysR, Transcriptional regulator Transcription 110636174 Common - helix-turn-helix protein, CopG Meso_3850 23 None None None 110636294 Common - D-galactarate dehydratase/Altronate hydrolase-like Meso_3970 73 COG2721 UxaA, Altronate dehydratase Carbohydrate transport and metabolism 110635560 Nonpathogen - hypothetical protein Meso_3231 6 None None None 110635603 Nonpathogen - hypothetical protein Meso_3275 2 None None None 110632701 Common - periplasmic sensor hybrid histidine kinase Meso_0340 212 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 110633229 Common - hypothetical protein Meso_0872 2 None None None 110636241 Common - GCN5-related N-acetyltransferase Meso_3917 191 COG0456 RimI, Acetyltransferases General function prediction only 110635180 Common - transcriptional regulator, LysR family Meso_2847 34 COG0583 LysR, Transcriptional regulator Transcription 110633420 Common - hypothetical protein Meso_1066 2 None None None 110634434 Common - hypothetical protein Meso_2084 27 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 110633820 Common - protein of unknown function UPF0047 Meso_1467 130 COG0432 COG0432, Uncharacterized conserved protein Function unknown 110633435 Common - FAD dependent oxidoreductase Meso_1081 96 COG0579 COG0579, Predicted dehydrogenase General function prediction only 110634562 Common - two component transcriptional regulator, winged helix family Meso_2213 214 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110636326 Common - type II secretion system protein Meso_4002 68 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 110636076 Common - 3-hydroxyacyl-CoA dehydrogenase, NAD-binding Meso_3751 161 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 110634330 Common - DinB Meso_1980 39 COG2318 DinB, Uncharacterized protein conserved in bacteria Function unknown 110635021 Common - urease accessory protein UreG Meso_2687 152 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 110636310 Common - penicillin-binding protein, 1A family Meso_3986 201 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 110633245 Nonpathogen - hypothetical protein Meso_0889 1 None None None 110634588 Common - ornithine carbamoyltransferase Meso_2240 237 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 110634319 Common - molybdopterin oxidoreductase Meso_1969 181 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 110634999 Nonpathogen - hypothetical protein Meso_2665 1 None None None 110633907 Common - nuclease (SNase-like) Meso_1554 66 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 110634864 Common - flavin reductase-like, FMN-binding Meso_2523 118 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 110633166 Common - binding-protein-dependent transport systems inner membrane component Meso_0809 108 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 110634662 Common - Conjugal transfer protein Meso_2317 34 COG3701 TrbF, Type IV secretory pathway, TrbF components Intracellular trafficking and secretion 110634182 Common - ABC transporter related Meso_1832 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 110633879 Nonpathogen - hypothetical protein Meso_1526 1 None None None 110634401 Common - protocatechuate 3,4-dioxygenase, alpha subunit Meso_2051 38 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 110635287 Common - short-chain dehydrogenase/reductase SDR Meso_2958 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110633386 Common - NADH dehydrogenase subunit K Meso_1032 86 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 110635333 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Meso_3004 204 COG0388 COG0388, Predicted amidohydrolase General function prediction only 110634454 Nonpathogen - hypothetical protein Meso_2105 1 None None None 110636206 Common - Twin-arginine translocation pathway signal Meso_3882 112 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 110634168 Common - DNA-directed RNA polymerase subunit beta' Meso_1818 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 110633798 Common rirA iron-responsive transcriptional regulator Meso_1445 161 COG1959 COG1959, Predicted transcriptional regulator Transcription 110633691 Common - protein of unknown function DUF305 Meso_1338 35 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 110633559 Nonpathogen - hypothetical protein Meso_1206 1 None None None 110635145 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Meso_2812 69 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 110636358 Common - integral membrane protein MviN Meso_4034 182 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 110632693 Common - Asp/Glu racemase Meso_0332 44 COG4126 COG4126, Hydantoin racemase Amino acid transport and metabolism 110633067 Common - hypothetical protein Meso_0710 23 None None None 110636071 Common - binding-protein-dependent transport systems inner membrane component Meso_3746 204 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 110632536 Common - protein of unknown function DUF849 Meso_0174 56 COG3246 COG3246, Uncharacterized conserved protein Function unknown 110635514 Common - inositol monophosphatase Meso_3185 214 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 110633894 Common - ABC transporter related Meso_1541 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 110636407 Common - Twin-arginine translocation pathway signal Meso_4083 106 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 110633791 Common - MotA/TolQ/ExbB proton channel Meso_1438 49 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 110635721 Common - outer membrane lipoprotein omp19 Meso_3393 7 None None None 110635095 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Meso_2761 167 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 110633614 Common - protein of unknown function DUF1624 Meso_1261 27 COG3503 COG3503, Predicted membrane protein Function unknown 110634862 Common - protein of unknown function DUF1185 Meso_2521 23 None None None 110636364 Common - protein of unknown function DUF1052 Meso_4040 30 COG5321 COG5321, Uncharacterized protein conserved in bacteria Function unknown 110632711 Common - putative GAF sensor protein Meso_0350 14 COG3605 PtsP, Signal transduction protein containing GAF and PtsI domains Signal transduction mechanisms 110635624 Common - transcriptional regulator, IclR family Meso_3296 109 COG1414 IclR, Transcriptional regulator Transcription 110634484 Common - cold-shock DNA-binding domain protein Meso_2135 177 COG1278 CspC, Cold shock proteins Transcription 110633024 Common - N-(5'-phosphoribosyl)anthranilate isomerase Meso_0667 195 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 110634626 Common - hypothetical protein Meso_2280 16 COG5502 COG5502, Uncharacterized conserved protein Function unknown 110635748 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase Meso_3420 218 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 110635732 Common - ABC transporter related Meso_3404 244 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 110635281 Common - AMP-dependent synthetase and ligase Meso_2952 222 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110636353 Nonpathogen - hypothetical protein Meso_4029 1 None None None 110636395 Common - protein of unknown function DUF892 Meso_4071 38 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 110635680 Common - protein of unknown function DUF214 Meso_3352 86 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 110634470 Common - Extensin-like Meso_2121 37 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 110635239 Common - two component transcriptional regulator, winged helix family Meso_2909 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110635828 Common - 2OG-Fe(II) oxygenase Meso_3500 57 COG3145 AlkB, Alkylated DNA repair protein DNA replication, recombination, and repair 110635816 Common - transcriptional regulator, XRE family Meso_3488 12 COG1396 HipB, Predicted transcriptional regulators Transcription 110633783 Common - Stress responsive alpha-beta barrel Meso_1430 12 None None None 110635851 Common - Allergen V5/Tpx-1 related Meso_3523 70 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 110635834 Common - hypothetical protein Meso_3506 25 COG5528 COG5528, Predicted integral membrane protein Function unknown 110635842 Common - fatty acid alpha hydroxylase Meso_3514 12 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 110635699 Common - major facilitator superfamily MFS_1 Meso_3371 130 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 110635872 Common - transcriptional regulator, LysR family Meso_3544 108 COG0583 LysR, Transcriptional regulator Transcription 110632581 Nonpathogen - hypothetical protein Meso_0220 1 None None None 110633271 Common - hypothetical protein Meso_0917 20 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 110633130 Nonpathogen - hypothetical protein Meso_0773 1 None None None 110633913 Common - drug resistance transporter, Bcr/CflA subfamily Meso_1560 227 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 110633126 Common - hypothetical protein Meso_0769 8 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 110634797 Common - homogentisate 1,2-dioxygenase Meso_2456 53 COG3508 HmgA, Homogentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 110634986 Common - aldehyde dehydrogenase Meso_2652 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 110633452 Common - ABC transporter related Meso_1098 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 110634500 Common - protein of unknown function DUF185 Meso_2151 95 COG1565 COG1565, Uncharacterized conserved protein Function unknown 110635223 Common - Pyrrolo-quinoline quinone Meso_2890 62 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 110635821 Common hisB imidazoleglycerol-phosphate dehydratase Meso_3493 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 110635849 Nonpathogen - hypothetical protein Meso_3521 5 None None None 110633187 Common - transcriptional regulator, GntR family Meso_0830 63 COG1802 GntR, Transcriptional regulators Transcription 110635640 Common - protein of unknown function DUF326 Meso_3312 31 None None None 110634877 Common - acyl-CoA synthetase Meso_2536 218 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110633220 Common - methionine-R-sulfoxide reductase Meso_0863 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 110635489 Common - protein of unknown function DUF6, transmembrane Meso_3160 182 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 110633117 Common - threonine synthase Meso_0760 160 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 110634699 Common - N-6 DNA methylase Meso_2355 61 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 110636392 Common - TRAP transporter, 4TM/12TM fusion protein Meso_4068 131 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 110633482 Common - delta-aminolevulinic acid dehydratase Meso_1129 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 110633523 Common clpX ATP-dependent protease ATP-binding subunit Meso_1170 225 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 110634101 Common - dihydrofolate reductase region Meso_1750 149 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 110634547 Common - cation diffusion facilitator family transporter Meso_2198 201 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 110635074 Common - lytic murein transglycosylase Meso_2740 102 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 110633394 Common - prolyl-tRNA synthetase Meso_1040 245 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110635121 Common - CBS domain containing protein Meso_2788 175 COG0517 COG0517, FOG: CBS domain General function prediction only 110636369 Common - putative permease ABC transporter protein Meso_4045 45 COG4135 COG4135, ABC-type uncharacterized transport system, permease component General function prediction only 110633984 Common - enolase Meso_1632 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 110633413 Common - Uncharacterized protein UPF0065 Meso_1059 72 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 110636006 Common - Putative hemolysin-like Meso_3681 70 COG3176 COG3176, Putative hemolysin General function prediction only 110636375 Common - Radical SAM Meso_4051 123 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 110635052 Common - GCN5-related N-acetyltransferase Meso_2718 84 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 110635709 Common - 3-isopropylmalate dehydrogenase Meso_3381 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 110635981 Common - purine nucleoside phosphorylase Meso_3656 161 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 110634542 Common - glutathione-dependent formaldehyde-activating, GFA Meso_2193 52 COG3791 COG3791, Uncharacterized conserved protein Function unknown 110634152 Common pcm protein-L-isoaspartate O-methyltransferase Meso_1801 152 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 110634895 Common - protein of unknown function UPF0118 Meso_2554 111 COG0628 PerM, Predicted permease General function prediction only 110636168 Common - DNA methylase N-4/N-6 Meso_3844 78 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 110636098 Common - binding-protein-dependent transport systems inner membrane component Meso_3773 162 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 110633993 Common - molybdenum cofactor synthesis domain Meso_1641 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 110633900 Nonpathogen - hypothetical protein Meso_1547 1 None None None 110633585 Nonpathogen - hypothetical protein Meso_1232 1 None None None 110635883 Common - ABC transporter related Meso_3556 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 110633552 Common - helicase-like Meso_1199 13 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 110634680 Common - hypothetical protein Meso_2335 15 None None None 110632902 Common - hypothetical protein Meso_0542 20 None None None 110632728 Common - protein of unknown function DUF224, cysteine-rich region Meso_0367 171 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 110635589 Common thiP thiamin transporter membrane protein Meso_3260 64 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 110636031 Common - ABC transporter related Meso_3706 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 110634819 Common - hypothetical protein Meso_2478 10 COG5605 COG5605, Predicted small integral membrane protein Function unknown 110633459 Nonpathogen - hypothetical protein Meso_1105 1 None None None 110635304 Common - ABC-type phosphate/phosphonate transport system periplasmic component-like Meso_2975 21 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 110634042 Common - basic membrane lipoprotein Meso_1690 86 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 110635363 Common - electron transfer flavoprotein, alpha subunit Meso_3034 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 110635771 Common rimM 16S rRNA-processing protein Meso_3443 187 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 110633383 Common - NADH dehydrogenase subunit H Meso_1029 186 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 110634507 Common - peptidyl-tRNA hydrolase Meso_2158 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 110634360 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase Meso_2010 218 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 110634979 Common - molybdopterin oxidoreductase Meso_2645 159 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 110636380 Common - hypothetical protein Meso_4056 188 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 110634881 Common - phenylalanine/histidine ammonia-lyase Meso_2540 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 110635005 Common - Alcohol dehydrogenase GroES-like Meso_2671 191 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 110632636 Common flbT flagellar biosynthesis repressor FlbT Meso_0275 24 COG5443 FlbT, Flagellar biosynthesis regulator FlbT Cell motility and secretion 110632808 Nonpathogen - hypothetical protein Meso_0447 1 None None None 110635917 Common - phosphoglyceromutase Meso_3591 172 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 110635170 Common - protein of unknown function DUF989 Meso_2837 38 COG3748 COG3748, Predicted membrane protein Function unknown 110635131 Common - short-chain dehydrogenase/reductase SDR Meso_2798 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110633369 Common - DNA topoisomerase IV subunit B Meso_1015 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 110634648 Common - binding-protein-dependent transport systems inner membrane component Meso_2303 189 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 110633062 Common - molybdenum cofactor biosynthesis protein B Meso_0705 190 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 110633852 Common - phenazine biosynthesis protein PhzF family Meso_1499 113 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 110634108 Common - permease YjgP/YjgQ Meso_1757 69 COG0795 COG0795, Predicted permeases General function prediction only 110633256 Common - two component transcriptional regulator, winged helix family Meso_0902 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 110635408 Common - protein of unknown function DUF6, transmembrane Meso_3079 55 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 110635570 Common - Glu/Leu/Phe/Val dehydrogenase, C terminal Meso_3241 167 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 110634413 Common - TonB-dependent receptor Meso_2063 121 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 110633888 Common - glutamyl-tRNA synthetase Meso_1535 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 110635232 Common - TRAP C4-dicarboxylate transport system permease DctM subunit Meso_2902 122 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 110635051 Nonpathogen - hypothetical protein Meso_2717 1 None None None 110633176 Common - Cupin 2, conserved barrel Meso_0819 16 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 110633881 Common - glycoside hydrolase 15-related Meso_1528 71 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 110632442 Common - transcriptional regulator, LysR family Meso_0080 152 COG0583 LysR, Transcriptional regulator Transcription 110635012 Common - trehalose synthase Meso_2678 174 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 110634531 Common - protein of unknown function DUF1355 Meso_2182 34 COG5426 COG5426, Uncharacterized membrane protein Function unknown 110632995 Common - hypothetical protein Meso_0638 20 None None None 110633148 Common - Animal haem peroxidase Meso_0791 90 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 110635148 Common - Twin-arginine translocation pathway signal Meso_2815 88 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 110634802 Nonpathogen - hypothetical protein Meso_2461 3 COG3254 COG3254, Uncharacterized conserved protein Function unknown 110634388 Nonpathogen - hypothetical protein Meso_2038 1 None None None 110632634 Common fliQ flagellar biosynthesis protein FliQ Meso_0273 50 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 110633416 Common - thiamine pyrophosphate enzyme-like TPP-binding Meso_1062 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 110634742 Common - Endoribonuclease L-PSP Meso_2400 86 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 110635765 Common pgk phosphoglycerate kinase Meso_3437 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 110636424 Common - formamidopyrimidine-DNA glycosylase Meso_4100 176 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 110634076 Common - type IV pilus assembly PilZ Meso_1725 12 None None None 110634964 Common - transcriptional regulator, LysR family Meso_2630 92 COG0583 LysR, Transcriptional regulator Transcription 110633339 Common - DNA repair protein RadA Meso_0985 206 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 110634634 Common - hypothetical protein Meso_2288 50 None None None 110634722 Common - transcriptional regulator, IclR family Meso_2380 124 COG1414 IclR, Transcriptional regulator Transcription 110632721 Common - ErfK/YbiS/YcfS/YnhG Meso_0360 89 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 110635795 Common - 6-phosphofructokinase Meso_3467 142 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 110635785 Common - gamma-glutamyl kinase Meso_3457 189 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 110633834 Common - nitroreductase Meso_1481 72 COG0778 NfnB, Nitroreductase Energy production and conversion 110633364 Common - hypothetical protein Meso_1010 13 None None None 110634419 Common - OmpA/MotB Meso_2069 57 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 110632395 Common - hypothetical protein Meso_0033 6 None None None 110635136 Nonpathogen - hypothetical protein Meso_2803 1 None None None 110633595 Nonpathogen - hypothetical protein Meso_1242 1 None None None 110633330 Common - aldo/keto reductase Meso_0976 192 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 110633464 Nonpathogen - hypothetical protein Meso_1111 3 None None None 110633780 Common - GCN5-related N-acetyltransferase Meso_1427 29 COG0456 RimI, Acetyltransferases General function prediction only 110632706 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Meso_0345 69 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 110635424 Common groEL chaperonin GroEL Meso_3095 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 110633422 Common - putative sulfopyruvate decarboxylase subunit alpha Meso_1068 27 COG4032 COG4032, Predicted thiamine-pyrophosphate-binding protein General function prediction only 110635439 Nonpathogen - protein of unknown function DUF1328 Meso_3110 1 COG5487 COG5487, Small integral membrane protein Function unknown 110636265 Nonpathogen - hypothetical protein Meso_3941 1 None None None 110632980 Common - Methyltransferase type 12 Meso_0623 23 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 110632369 Common hslO Hsp33-like chaperonin Meso_0007 135 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 110633376 Common - NADH dehydrogenase subunit A Meso_1022 162 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 110633819 Common - hypothetical protein Meso_1466 22 COG4274 COG4274, Uncharacterized conserved protein Function unknown 110632966 Common - putative CpaB2 pilus assembly protein Meso_0609 58 COG3745 CpaB, Flp pilus assembly protein CpaB Intracellular trafficking and secretion 110633129 Common - pyruvate phosphate dikinase Meso_0772 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 110633226 Common - putative monovalent cation/H+ antiporter subunit F Meso_0869 28 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 110632686 Common - protein tyrosine phosphatase Meso_0325 118 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 110633033 Common pheS phenylalanyl-tRNA synthetase subunit alpha Meso_0676 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 110632439 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Meso_0077 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 110633193 Common - PfkB Meso_0836 158 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 110634913 Common - transcriptional regulator, AraC family Meso_2572 72 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 110634377 Common - Orn/DAP/Arg decarboxylase 2 Meso_2027 198 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 110634604 Common - sulphate transporter Meso_2257 162 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 110636084 Common - transcriptional regulator, GntR family Meso_3759 110 COG1802 GntR, Transcriptional regulators Transcription 110632452 Common - periplasmic sensor hybrid histidine kinase Meso_0090 221 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 110633541 Common - hypothetical protein Meso_1188 10 None None None 110633802 Common - nitrate transporter component, nrtA Meso_1449 78 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 110634650 Common - extracellular solute-binding protein, family 1 Meso_2305 99 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 110632831 Common - ribosomal RNA methyltransferase RrmJ/FtsJ Meso_0470 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 110633967 Common trkA potassium transporter peripheral membrane component Meso_1615 142 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 110636185 Common - hypothetical protein Meso_3861 11 COG5639 COG5639, Uncharacterized conserved small protein Function unknown 110633151 Common - type I secretion membrane fusion protein, HlyD family Meso_0794 124 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 110634373 Nonpathogen - hypothetical protein Meso_2023 1 None None None 110636344 Common - protein of unknown function UPF0126 Meso_4020 129 COG2860 COG2860, Predicted membrane protein Function unknown 110632856 Common - phage integrase Meso_0496 113 COG0582 XerC, Integrase DNA replication, recombination, and repair 110636091 Common - aldehyde dehydrogenase Meso_3766 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 110636422 Common - hypothetical protein Meso_4098 14 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 110636224 Common - aldo/keto reductase Meso_3900 175 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 110635700 Common - protein of unknown function YGGT Meso_3372 28 COG0762 COG0762, Predicted integral membrane protein Function unknown 110636250 Nonpathogen - hypothetical protein Meso_3926 1 None None None 110635381 Common - aldo/keto reductase Meso_3052 133 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 110635475 Common - pseudouridine synthase, RluA family Meso_3146 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 110636179 Common - conjugal transfer protein trbJ Meso_3855 22 COG5314 COG5314, Conjugal transfer/entry exclusion protein Intracellular trafficking and secretion 110634386 Common - L-carnitine dehydratase/bile acid-inducible protein F Meso_2036 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 110633986 Common - CTP synthetase Meso_1634 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 110632374 Common - histidine kinase Meso_0012 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 110634424 Common - protein of unknown function DUF983 Meso_2074 22 COG5349 COG5349, Uncharacterized protein conserved in bacteria Function unknown 110633775 Common - protein of unknown function DUF1697 Meso_1422 28 COG3797 COG3797, Uncharacterized protein conserved in bacteria Function unknown 110633958 Common - inner-membrane translocator Meso_1606 114 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 110634324 Common - short chain dehydrogenase Meso_1974 232 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110634448 Nonpathogen - hypothetical protein Meso_2099 2 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 110636372 Common - bacterioferritin Meso_4048 107 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 110635403 Common rpmB 50S ribosomal protein L28 Meso_3074 149 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 110635788 Common rpmA 50S ribosomal protein L27 Meso_3460 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 110634026 Common - ribosomal protein S19 Meso_1674 247 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 110635327 Common - modification methylase, HemK family Meso_2998 232 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 110635971 Common - transcriptional regulator, IclR family Meso_3645 118 COG1414 IclR, Transcriptional regulator Transcription 110632939 Common - molybdopterin dehydrogenase, FAD-binding Meso_0581 97 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 110634271 Common - transcriptional regulator, MarR family Meso_1921 109 COG1846 MarR, Transcriptional regulators Transcription 110632612 Nonpathogen - hypothetical protein Meso_0251 2 None None None 110636198 Common - carbamate kinase Meso_3874 65 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 110633254 Common - cytochrome C biogenesis protein Meso_0900 93 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 110635521 Common - hypothetical protein Meso_3192 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 110634005 Common - ribosomal protein L17 Meso_1653 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 110632814 Nonpathogen - hypothetical protein Meso_0453 1 None None None 110633260 Common - aminopeptidase N Meso_0906 159 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 110634089 Common - hypothetical protein Meso_1738 6 None None None 110632416 Common - fumarylacetoacetate (FAA) hydrolase Meso_0054 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 110632498 Common - ABC transporter related Meso_0136 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 110634080 Common - serine O-acetyltransferase Meso_1729 194 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 110634465 Common - glycosyl transferase, family 25 Meso_2116 16 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 110634537 Nonpathogen - hypothetical protein Meso_2188 1 None None None 110634791 Common - 4Fe-4S ferredoxin, iron-sulfur binding Meso_2450 167 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 110635316 Common - N-formimino-L-glutamate deiminase Meso_2987 118 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 110634211 Common - FAD dependent oxidoreductase Meso_1861 147 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 110635543 Common - hypothetical protein Meso_3214 6 None None None 110635160 Common - SpoVT/AbrB-like Meso_2827 21 COG4456 VagC, Virulence-associated protein and related proteins Function unknown 110635909 Common - Mg chelatase, subunit ChlI Meso_3583 187 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 110632836 Common - ABC transporter related Meso_0475 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 110634447 Common - Cupin 2, conserved barrel Meso_2098 67 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 110634351 Common - cell division protein FtsZ Meso_2001 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 110635932 Common rpsA 30S ribosomal protein S1 Meso_3606 218 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 110635357 Common - putative ribonuclease BN Meso_3028 76 COG1295 Rbn, Predicted membrane protein Function unknown 110632493 Common - ABC-2 type transporter Meso_0131 125 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 110636228 Common - Twin-arginine translocation pathway signal Meso_3904 191 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 110634840 Common - Twin-arginine translocation pathway signal Meso_2499 95 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 110635175 Common - cobalamin synthesis protein, P47K Meso_2842 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 110632932 Common - transcriptional regulator, AraC family Meso_0574 139 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 110635362 Common - electron transfer flavoprotein beta-subunit Meso_3033 153 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 110635924 Common - Domain of unknown function DUF1730 Meso_3598 134 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 110634143 Common - tRNA (uracil-5-)-methyltransferase Gid Meso_1792 81 COG1206 Gid, NAD(FAD)-utilizing enzyme possibly involved in translation Translation, ribosomal structure and biogenesis 110635039 Common - ATPase, BadF/BadG/BcrA/BcrD type Meso_2705 61 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 110635569 Common - OsmC-like protein Meso_3240 93 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 110636064 Common - binding-protein-dependent transport systems inner membrane component Meso_3739 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110633850 Common - BA14K-like Meso_1497 7 None None None 110634399 Common - 4-carboxymuconolactone decarboxylase Meso_2049 81 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 110635138 Common - putative NAD(P) transhydrogenase subunit alpha PART 2 transmembrane protein Meso_2805 117 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 110632958 Common - response regulator receiver modulated CheB methylesterase Meso_0601 151 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 110634154 Common - seryl-tRNA synthetase Meso_1803 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 110633664 Common - binding-protein-dependent transport systems inner membrane component Meso_1311 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110636088 Common - aldo/keto reductase Meso_3763 198 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 110634064 Common - peptidase M48, Ste24p Meso_1712 99 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 110634493 Common - protein of unknown function DUF982 Meso_2144 2 None None None 110632394 Common - ATP-dependent DNA ligase Meso_0032 105 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 110634628 Common - protein of unknown function DUF214 Meso_2282 44 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 110635336 Common - Methyltransferase type 11 Meso_3007 71 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 110635045 Common - high-affinity nickel-transporter Meso_2711 44 COG2215 COG2215, ABC-type uncharacterized transport system, permease component General function prediction only 110634255 Common - cytochrome c, class I Meso_1905 54 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 110635209 Common - polysaccharide deacetylase Meso_2876 14 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 110634435 Common - hypothetical protein Meso_2085 7 None None None 110632756 Common - FAD dependent oxidoreductase Meso_0395 117 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 110635392 Nonpathogen - hypothetical protein Meso_3063 1 None None None 110632885 Common - hypothetical protein Meso_0525 9 COG5419 COG5419, Uncharacterized conserved protein Function unknown 110635604 Common - Cupin 2, conserved barrel Meso_3276 33 COG3435 COG3435, Gentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 110634238 Common - phage protein, HK97 gp10 family Meso_1888 7 None None None 110632782 Common - hypothetical protein Meso_0421 2 None None None 110635996 Common - signal peptide peptidase SppA, 36K type Meso_3671 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 110634640 Common - glucose-inhibited division protein A Meso_2295 28 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 110635797 Common - Cobyrinic acid a,c-diamide synthase Meso_3469 206 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 110633091 Common - Pirin-like Meso_0734 142 COG1741 COG1741, Pirin-related protein General function prediction only 110634400 Common - protocatechuate 3,4-dioxygenase, beta subunit Meso_2050 52 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 110634621 Common - hypothetical protein Meso_2275 3 None None None 110634771 Common - molybdenum cofactor synthesis domain Meso_2430 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 110635163 Common - hypothetical protein Meso_2830 33 COG3257 GlxB, Uncharacterized protein, possibly involved in glyoxylate utilization General function prediction only 110636038 Common - TRAP dicarboxylate transporter, DctM subunit Meso_3713 122 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 110633099 Common - cytochrome c oxidase, subunit I Meso_0742 173 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 110635030 Common - glycosyl transferase, group 1 Meso_2696 21 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 110633865 Common - Lytic transglycosylase, catalytic Meso_1512 83 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 110635596 Common - hypothetical protein Meso_3267 19 COG5515 COG5515, Uncharacterized conserved small protein Function unknown 110632742 Common - diguanylate cyclase Meso_0381 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 110635301 Common - conserved hypothetical protein 698 Meso_2972 115 COG2855 COG2855, Predicted membrane protein Function unknown 110632440 Common - Creatininase Meso_0078 62 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 110633436 Common - amidohydrolase Meso_1082 75 COG1001 AdeC, Adenine deaminase Nucleotide transport and metabolism 110633324 Common - RarD protein, DMT superfamily transporter Meso_0970 95 COG2962 RarD, Predicted permeases General function prediction only 110633071 Common glyS glycyl-tRNA synthetase subunit beta Meso_0714 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 110633124 Common - DSBA oxidoreductase Meso_0767 99 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 110634983 Common - binding-protein-dependent transport systems inner membrane component Meso_2649 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110635106 Common - hypothetical protein Meso_2773 45 COG3569 COG3569, Topoisomerase IB DNA replication, recombination, and repair 110635577 Common - GCN5-related N-acetyltransferase Meso_3248 16 COG0456 RimI, Acetyltransferases General function prediction only 110635027 Common - Phosphoglycerate mutase Meso_2693 117 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 110632678 Common - RNA binding S1 Meso_0317 166 COG2183 Tex, Transcriptional accessory protein Transcription 110633960 Common - ABC transporter related Meso_1608 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 110632626 Common - ABC transporter related Meso_0265 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 110635942 Common - short-chain dehydrogenase/reductase SDR Meso_3616 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110634755 Common - conserved repeat domain Meso_2414 52 None None None 110634707 Common - cystathionine beta-lyase Meso_2364 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 110632893 Common - hypothetical protein Meso_0533 21 None None None 110635861 Common - cytochrome C oxidase subunit IV Meso_3533 33 COG3125 CyoD, Heme/copper-type cytochrome/quinol oxidase, subunit 4 Energy production and conversion 110632449 Nonpathogen - hypothetical protein Meso_0087 3 None None None 110633401 Common - Uncharacterized protein UPF0065 Meso_1047 76 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 110633759 Common tgt queuine tRNA-ribosyltransferase Meso_1406 228 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 110634657 Common - autoinducer synthesis protein Meso_2312 27 COG3916 LasI, N-acyl-L-homoserine lactone synthetase Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 110632899 Common - Domain of unknown function DUF1738 Meso_0539 48 COG4227 COG4227, Antirestriction protein DNA replication, recombination, and repair 110632528 Common - binding-protein-dependent transport systems inner membrane component Meso_0166 218 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 110636109 Common - FGGY-family pentulose kinase Meso_3784 173 COG1069 AraB, Ribulose kinase Energy production and conversion 110635951 Common - transcriptional regulator, GntR family Meso_3625 114 COG2188 PhnF, Transcriptional regulators Transcription 110633317 Common - NUDIX hydrolase Meso_0963 113 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 110635612 Common - hypothetical protein Meso_3284 70 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 110633713 Common - acyl-CoA dehydrogenase-like Meso_1360 146 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 110634119 Common - 3-ketoacyl-(acyl-carrier-protein) reductase NodG Meso_1768 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110633767 Common - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase Meso_1414 202 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 110634390 Nonpathogen - hypothetical protein Meso_2040 4 None None None 110634686 Nonpathogen - hypothetical protein Meso_2342 12 COG5489 COG5489, Uncharacterized conserved protein Function unknown 110634112 Common pdxA 4-hydroxythreonine-4-phosphate dehydrogenase Meso_1761 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 110633654 Common - hypothetical protein Meso_1301 66 COG3285 COG3285, Predicted eukaryotic-type DNA primase DNA replication, recombination, and repair 110636339 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Meso_4015 31 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 110632382 Common - hypothetical protein Meso_0020 21 COG0824 FcbC, Predicted thioesterase General function prediction only 110632789 Common - Pseudouridine synthase, Rsu Meso_0428 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 110633355 Common - Twin-arginine translocation pathway signal Meso_1001 188 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 110634779 Common - DNA binding domain, excisionase family Meso_2438 71 COG1910 COG1910, Periplasmic molybdate-binding protein/domain Inorganic ion transport and metabolism 110636292 Common - Uncharacterized protein UPF0065 Meso_3968 75 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 110633080 Common - acyl-CoA dehydrogenase-like Meso_0723 143 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 110634972 Common - urocanate hydratase Meso_2638 97 COG2987 HutU, Urocanate hydratase Amino acid transport and metabolism 110635714 Common - putative transcriptional regulator, XRE family Meso_3386 16 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 110634925 Common - DegT/DnrJ/EryC1/StrS aminotransferase Meso_2584 193 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 110634676 Common - Lytic transglycosylase, catalytic Meso_2331 158 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 110633532 Common - NUDIX hydrolase Meso_1179 110 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 110633842 Common ilvH acetolactate synthase 3 regulatory subunit Meso_1489 188 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 110634282 Common - putative sarcosine oxidase alpha subunit Meso_1932 30 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 110635655 Common - hypothetical protein Meso_3327 8 None None None 110633625 Common - drug resistance transporter, Bcr/CflA subfamily Meso_1272 188 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 110634937 Common - hypothetical protein Meso_2596 6 None None None 110636018 Common - ABC-2 type transporter Meso_3693 113 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 110632871 Common - HipA-like Meso_0511 66 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 110633579 Nonpathogen - hypothetical protein Meso_1226 5 None None None 110635679 Common - ABC transporter related Meso_3351 249 COG4181 COG4181, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 110636158 Nonpathogen - hypothetical protein Meso_3834 8 None None None 110634231 Common - hypothetical protein Meso_1881 38 COG4764 COG4764, Uncharacterized protein conserved in bacteria Function unknown 110633722 Nonpathogen - hypothetical protein Meso_1369 9 None None None 110634514 Common - cytochrome b/b6-like Meso_2165 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 110633877 Common - 3-hydroxyacyl-CoA dehydrogenase, NAD-binding Meso_1524 164 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 110632515 Common - chromate transporter, chromate ion transporter (CHR) family Meso_0153 107 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 110634566 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase Meso_2217 221 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 110635159 Common - PilT protein-like Meso_2826 54 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 110633642 Common - flavin reductase-like, FMN-binding Meso_1289 107 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 110636138 Common - Domain of unknown function DUF1738 Meso_3814 48 COG4227 COG4227, Antirestriction protein DNA replication, recombination, and repair 110633624 Common - PP-loop Meso_1271 155 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 110633525 Common - histone-like DNA-binding protein Meso_1172 213 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 110634097 Common - protease Do Meso_1746 224 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 110634486 Common - hypothetical protein Meso_2137 10 None None None 110634126 Common - glutathione-dependent formaldehyde-activating, GFA Meso_1775 34 COG3791 COG3791, Uncharacterized conserved protein Function unknown 110632461 Common - hypothetical protein Meso_0099 26 None None None 110635649 Common - transcriptional regulator, GntR family Meso_3321 115 COG1802 GntR, Transcriptional regulators Transcription 110632892 Nonpathogen - hypothetical protein Meso_0532 1 None None None 110635260 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Meso_2931 47 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 110632574 Nonpathogen - hypothetical protein Meso_0212 1 None None None 110633648 Common - phospholipase/Carboxylesterase Meso_1295 6 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 110636272 Common - putative transcriptional regulator, AsnC family Meso_3948 22 COG1522 Lrp, Transcriptional regulators Transcription 110636257 Common - signal transduction histidine kinase Meso_3933 48 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 110636129 Common - Resolvase-like Meso_3805 71 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 110633056 Common - F0F1 ATP synthase subunit B Meso_0699 29 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 110635666 Nonpathogen - hypothetical protein Meso_3338 1 None None None 110634736 Common - hypothetical protein Meso_2394 4 None None None 110633607 Nonpathogen - hypothetical protein Meso_1254 3 None None None 110633282 Nonpathogen - hypothetical protein Meso_0928 1 None None None 110635503 Common - MotA/TolQ/ExbB proton channel Meso_3174 127 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 110635894 Common - hypothetical protein Meso_3568 20 COG5488 COG5488, Integral membrane protein Function unknown 110634134 Common - hypothetical protein Meso_1783 87 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 110634524 Common - hypothetical protein Meso_2175 4 COG5466 COG5466, Predicted small metal-binding protein Function unknown 110633046 Nonpathogen - hypothetical protein Meso_0689 1 None None None 110634918 Nonpathogen - hypothetical protein Meso_2577 7 None None None 110636332 Common - CsbD-like Meso_4008 55 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 110633729 Common - histidine triad (HIT) protein Meso_1376 237 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 110633574 Nonpathogen - hypothetical protein Meso_1221 2 None None None 110632736 Common rnpA ribonuclease P Meso_0375 9 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 110634616 Nonpathogen - hypothetical protein Meso_2270 2 None None None 110635266 Common - TRAP C4-dicarboxylate transport system permease DctM subunit Meso_2937 122 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 110636276 Common - transcriptional regulator, MarR family Meso_3952 16 COG1846 MarR, Transcriptional regulators Transcription 110633471 Common - hypothetical protein Meso_1118 14 COG4391 COG4391, Uncharacterized protein conserved in bacteria Function unknown 110636046 Common - luciferase-like Meso_3721 122 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 110632790 Common - putative methyltransferase Meso_0429 211 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 110634452 Common - Lytic transglycosylase, catalytic Meso_2103 26 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 110635271 Common - short chain dehydrogenase Meso_2942 238 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 110636404 Common - ABC transporter related Meso_4080 249 COG4172 COG4172, ABC-type uncharacterized transport system, duplicated ATPase component General function prediction only 110635507 Common ruvA Holliday junction DNA helicase motor protein Meso_3178 208 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 110636113 Nonpathogen - hypothetical protein Meso_3788 3 None None None 110635925 Common - glutathione S-transferase-like Meso_3599 41 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 110635870 Common - NLPA lipoprotein Meso_3542 69 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 110633681 Common - Excinuclease ABC, C subunit-like Meso_1328 52 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 110636300 Common - polar amino acid ABC transporter, inner membrane subunit Meso_3976 171 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 110634383 Common - putative ABC transporter ATP-binding protein Meso_2033 248 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 110634578 Nonpathogen - hypothetical protein Meso_2230 9 None None None 110635086 Common - polysaccharide deacetylase Meso_2752 92 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 110635672 Common - argininosuccinate synthase Meso_3344 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 110634120 Common - malonyl CoA-acyl carrier protein transacylase Meso_1769 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 110632420 Common - (2Fe-2S)-binding Meso_0058 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 110633827 Common - DGPFAETKE domain containing protein Meso_1474 37 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 110634582 Common - alpha-glucan phosphorylases Meso_2234 150 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 110633812 Common - ribose-5-phosphate isomerase A Meso_1459 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 110636144 Common - hypothetical protein Meso_3820 8 None None None 110636313 Common - uroporphyrin-III C-methyltransferase Meso_3989 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 110633592 Common - hypothetical protein Meso_1239 18 None None None 110635110 Nonpathogen - hypothetical protein Meso_2777 10 COG4641 COG4641, Uncharacterized protein conserved in bacteria Function unknown 110633320 Common - protein of unknown function DUF559 Meso_0966 47 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 110633406 Common - thiamine pyrophosphate enzyme-like TPP-binding Meso_1052 40 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 110633741 Common - surface antigen (D15) Meso_1388 157 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 110635379 Common - Asp/Glu racemase Meso_3050 39 COG3473 COG3473, Maleate cis-trans isomerase Secondary metabolites biosynthesis, transport, and catabolism 110635656 Common - Extracellular ligand-binding receptor Meso_3328 140 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 110634407 Common - putative oxidoreductase Meso_2057 184 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 110633496 Common - Ubiquinol-cytochrome C chaperone Meso_1143 22 COG5452 COG5452, Uncharacterized conserved protein Function unknown 110634805 Common - flavin reductase-like, FMN-binding Meso_2464 108 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 110633233 Nonpathogen - hypothetical protein Meso_0876 1 None None None 110634949 Common - 40-residue YVTN family beta-propeller repeat protein Meso_2611 84 COG3391 COG3391, Uncharacterized conserved protein Function unknown 110635491 Common - phosphoserine aminotransferase Meso_3162 70 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 110635202 Common - ABC transporter related Meso_2869 249 COG1101 PhnK, ABC-type uncharacterized transport system, ATPase component General function prediction only 110635916 Common - hypothetical protein Meso_3590 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 110635768 Common - transketolase Meso_3440 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 110634574 Common - DNA polymerase III, epsilon subunit Meso_2226 136 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 110635525 Common - 5-formyltetrahydrofolate cyclo-ligase Meso_3196 173 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 110633203 Common - 2-dehydro-3-deoxy-6-phosphogalactonate aldolase Meso_0846 123 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 110633269 Common - Methyltransferase type 12 Meso_0915 36 COG3963 COG3963, Phospholipid N-methyltransferase Lipid metabolism 110633951 Common - transcriptional regulator, AraC family Meso_1599 143 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 110633568 Common - hypothetical protein Meso_1215 21 COG3566 COG3566, Uncharacterized protein conserved in bacteria Function unknown 110634930 Common - sugar transferase Meso_2589 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 110632593 Common - hypothetical protein Meso_0232 9 None None None 110632904 Common - type III restriction enzyme, res subunit Meso_0544 41 COG3587 COG3587, Restriction endonuclease Defense mechanisms 110635881 Common - sugar isomerase (SIS) Meso_3554 81 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 110633349 Common - Xylose isomerase-like TIM barrel Meso_0995 13 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 110636000 Nonpathogen - hypothetical protein Meso_3675 2 None None None 110636079 Common - glucose-methanol-choline oxidoreductase Meso_3754 94 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 110633476 Common - hypothetical protein Meso_1123 6 None None None 110634175 Common secE preprotein translocase subunit SecE Meso_1825 25 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 110634729 Common - protein of unknown function DUF112, transmembrane Meso_2387 76 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 110634357 Common murG N-acetylglucosaminyl transferase Meso_2007 208 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 110632388 Common - protein of unknown function DUF81 Meso_0026 128 COG0730 COG0730, Predicted permeases General function prediction only 110633909 Common - hypothetical protein Meso_1556 74 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 110634044 Common - inner-membrane translocator Meso_1692 103 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 110633022 Common - CutA1 divalent ion tolerance protein Meso_0665 119 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 110636057 Common - Hydantoinase B/oxoprolinase Meso_3732 95 COG0146 HyuB, N-methylhydantoinase B/acetone carboxylase, alpha subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110633673 Common - acyl carrier protein Meso_1320 112 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110633247 Nonpathogen - hypothetical protein Meso_0893 1 None None None 110633745 Common - protein of unknown function DUF1009 Meso_1392 45 COG3494 COG3494, Uncharacterized protein conserved in bacteria Function unknown 110633119 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Meso_0762 160 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 110633104 Common - Surfeit locus 1 Meso_0747 58 COG3346 COG3346, Uncharacterized conserved protein Function unknown 110634639 Common - Shikimate dehydrogenase substrate binding-like Meso_2294 216 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 110632806 Common - protein of unknown function DUF442 Meso_0445 44 COG3453 COG3453, Uncharacterized protein conserved in bacteria Function unknown 110633004 Common - glycosyl transferase, family 2 Meso_0647 159 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 110635642 Common - putative tricarboxylic transport membrane protein Meso_3314 15 None None None 110635280 Common - Enoyl-CoA hydratase/isomerase Meso_2951 183 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 110632552 Common hisD histidinol dehydrogenase Meso_0190 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 110634598 Common - cytochrome c oxidase, cbb3-type, subunit II Meso_2251 82 COG2993 CcoO, Cbb3-type cytochrome oxidase, cytochrome c subunit Energy production and conversion 110633374 Common - Carbamoyl-phosphate synthase L chain, ATP-binding Meso_1020 238 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 110635032 Common - Methionine synthase, vitamin-B12 independent Meso_2698 48 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 110635777 Common - dinucleoside polyphosphate hydrolase Meso_3449 112 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 110633418 Common - tricarballylate dehydrogenase Meso_1064 82 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 110636014 Common - transcriptional regulator, AraC family Meso_3689 127 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 110633164 Common - ABC transporter related Meso_0807 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 110635739 Common - phosphoribosylaminoimidazole carboxylase, catalytic subunit Meso_3411 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 110634332 Common - protein of unknown function DUF1321 Meso_1982 40 COG3814 COG3814, Uncharacterized protein conserved in bacteria Function unknown 110635908 Common - thioredoxin Meso_3582 234 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 110632406 Common - transcriptional regulator, GntR family Meso_0044 184 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 110634738 Common - Mandelate racemase/muconate lactonizing enzyme-like Meso_2396 105 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 110632778 Nonpathogen - hypothetical protein Meso_0417 1 None None None 110633214 Common - methylmalonyl-CoA mutase Meso_0857 108 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 110636217 Common - heavy metal translocating P-type ATPase Meso_3893 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 110633388 Common - NADH dehydrogenase subunit M Meso_1034 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 110634653 Common - short-chain dehydrogenase/reductase SDR Meso_2308 234 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110633069 Common - Tetratricopeptide TPR_2 Meso_0712 165 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 110634314 Common - protein of unknown function UPF0118 Meso_1964 178 COG0628 PerM, Predicted permease General function prediction only 110636041 Common - Cupin 2, conserved barrel Meso_3716 14 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 110635534 Common - YciI-like protein Meso_3205 46 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 110634227 Common - hypothetical protein Meso_1877 33 COG3809 COG3809, Uncharacterized protein conserved in bacteria Function unknown 110635077 Common gltD glutamate synthase subunit beta Meso_2743 199 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 110635975 Common - protein of unknown function DUF1470 Meso_3650 23 COG5516 COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding General function prediction only 110632540 Common - TRAP transporter, 4TM/12TM fusion protein Meso_0178 117 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 110635211 Common - glycosyl transferase, group 1 Meso_2878 130 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 110635741 Common - hypothetical protein Meso_3413 41 None None None 110636305 Common - methionine sulfoxide reductase A Meso_3981 204 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 110632689 Common metH B12-dependent methionine synthase Meso_0328 176 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 110635093 Common - hypothetical protein Meso_2759 7 None None None 110632990 Common - hypothetical protein Meso_0633 62 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 110632713 Common - pyridine nucleotide-disulphide oxidoreductase dimerisation region Meso_0352 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 110635706 Common - 4Fe-4S ferredoxin, iron-sulfur binding Meso_3378 155 COG1146 COG1146, Ferredoxin Energy production and conversion 110635285 Common - RNA polymerase, sigma 54 subunit, RpoN Meso_2956 144 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 110633785 Common - 3-methyladenine DNA glycosylase Meso_1432 80 COG2094 Mpg, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 110632559 Nonpathogen - hypothetical protein Meso_0197 1 None None None 110632905 Common - ATP-dependent endonuclease of the OLD family-like Meso_0545 38 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 110634208 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Meso_1858 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 110633902 Common - tRNA-dihydrouridine synthase A Meso_1549 209 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 110632397 Common - ABC transporter related Meso_0035 249 COG4172 COG4172, ABC-type uncharacterized transport system, duplicated ATPase component General function prediction only 110632682 Common minE cell division topological specificity factor MinE Meso_0321 76 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 110632841 Common - putative cyclase Meso_0480 55 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 110633031 Common rplT 50S ribosomal protein L20 Meso_0674 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 110633915 Common - extracellular solute-binding protein, family 3 Meso_1562 178 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 110633448 Common - extracellular solute-binding protein, family 1 Meso_1094 91 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 110634186 Common - Endoribonuclease L-PSP Meso_1836 80 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 110636341 Common hrcA heat-inducible transcription repressor Meso_4017 148 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 110632547 Common - zinc-binding protein Meso_0185 45 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 110634346 Common - AzlC-like Meso_1996 108 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 110633265 Common - electron transfer flavoprotein-ubiquinone oxidoreductase Meso_0911 110 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 110634892 Nonpathogen - hypothetical protein Meso_2551 1 None None None 110635126 Common - cytochrome c, class I Meso_2793 61 COG2863 COG2863, Cytochrome c553 Energy production and conversion 110633810 Common - MscS Mechanosensitive ion channel Meso_1457 93 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 110635249 Nonpathogen - DoxX Meso_2920 1 COG2259 COG2259, Predicted membrane protein Function unknown 110633706 Common - ribonuclease R Meso_1353 192 COG0557 VacB, Exoribonuclease R Transcription 110633814 Common - glutathione reductase Meso_1461 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 110635443 Common - D-xylose ABC transporter, periplasmic substrate-binding protein Meso_3114 93 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 110633112 Common - cation diffusion facilitator family transporter Meso_0755 128 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 110636289 Common - Malate/L-lactate dehydrogenase Meso_3965 67 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 110635228 Nonpathogen - hypothetical protein Meso_2897 1 None None None 110635832 Nonpathogen - hypothetical protein Meso_3504 10 None None None 110633955 Common - hypothetical protein Meso_1603 18 None None None 110632797 Common - hypothetical protein Meso_0436 24 None None None 110635014 Common - Urease accessory protein UreD Meso_2680 81 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 110634308 Common - aldehyde dehydrogenase Meso_1958 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 110635417 Common - phospholipid/glycerol acyltransferase Meso_3088 180 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 110634312 Nonpathogen - hypothetical protein Meso_1962 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 110635582 Common - protein of unknown function DUF1244 Meso_3253 38 COG3492 COG3492, Uncharacterized protein conserved in bacteria Function unknown 110636363 Common - transcriptional regulator, MerR family Meso_4039 148 COG0789 SoxR, Predicted transcriptional regulators Transcription 110634856 Common - ribose-5-phosphate isomerase B Meso_2515 128 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 110636214 Common - alpha-glucan phosphorylases Meso_3890 141 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 110633342 Common - Cyclopropane-fatty-acyl-phospholipid synthase Meso_0988 137 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 110633392 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Meso_1038 93 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 110633734 Common - ribosomal protein S2 Meso_1381 221 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 110634915 Common - two component transcriptional regulator, LuxR family Meso_2574 117 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 110633513 Common - cytochrome oxidase assembly Meso_1160 77 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 110635146 Common - TRAP dicarboxylate transporter, DctM subunit Meso_2813 122 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 110632923 Common - argininosuccinate lyase Meso_0564 225 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 110632432 Common pgi glucose-6-phosphate isomerase Meso_0070 196 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 110633083 Common - heat shock protein DnaJ-like Meso_0726 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 110633554 Nonpathogen - hypothetical protein Meso_1201 1 None None None 110634301 Common - binding-protein-dependent transport systems inner membrane component Meso_1951 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110634702 Common - aminotransferase, class IV Meso_2359 191 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 110636336 Common - hypothetical protein Meso_4012 34 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 110635626 Common - protein of unknown function DUF1468 Meso_3298 24 None None None 110632868 Common - Conjugal transfer protein TrbC Meso_0508 22 COG3838 VirB2, Type IV secretory pathway, VirB2 components (pilins) Intracellular trafficking and secretion 110632900 Common - hypothetical protein Meso_0540 61 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 110636377 Common - exsB protein Meso_4053 166 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 110636413 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase Meso_4089 216 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 110632912 Common - protein of unknown function DUF955 Meso_0552 17 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 110632997 Common - Uncharacterised conserved protein UCP028101 Meso_0640 24 COG3490 COG3490, Uncharacterized protein conserved in bacteria Function unknown 110634558 Common - hypothetical protein Meso_2209 13 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 110632722 Common - protein of unknown function DUF224, cysteine-rich region Meso_0361 181 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 110633146 Common - TRAP dicarboxylate transporter, DctP subunit Meso_0789 106 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 110634957 Common - extracellular solute-binding protein, family 5 Meso_2622 176 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 110633886 Common - transcriptional regulator, ArsR family Meso_1533 168 COG0640 ArsR, Predicted transcriptional regulators Transcription 110633284 Common - carboxyl transferase Meso_0930 143 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 110634159 Common - putative transcriptional regulator Meso_1808 143 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 110632981 Common - homocysteine S-methyltransferase Meso_0624 18 COG2040 MHT1, Homocysteine/selenocysteine methylase (S-methylmethionine-dependent) Amino acid transport and metabolism 110634445 Nonpathogen - hypothetical protein Meso_2096 1 None None None 110632718 Common groEL chaperonin GroEL Meso_0357 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 110635369 Common - diaminopimelate decarboxylase Meso_3040 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 110632796 Common - inositol monophosphatase Meso_0435 169 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 110634074 Common - Rhomboid-like protein Meso_1723 79 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 110634253 Nonpathogen - hypothetical protein Meso_1903 1 None None None 110636068 Common - spermidine/putrescine ABC transporter ATPase subunit Meso_3743 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 110633318 Common - protein of unknown function DUF159 Meso_0964 97 COG2135 COG2135, Uncharacterized conserved protein Function unknown 110634190 Common - MATE efflux family protein Meso_1840 88 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 110632750 Common - succinyl-diaminopimelate desuccinylase Meso_0389 209 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 110635692 Common - GTP-binding protein TypA Meso_3364 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 110633995 Common - putative protein-S-isoprenylcysteine methyltransferase Meso_1643 33 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 110634675 Common - hypothetical protein Meso_2330 26 COG3843 VirD2, Type IV secretory pathway, VirD2 components (relaxase) Intracellular trafficking and secretion 110635939 Common - transcriptional regulator, IclR family Meso_3613 106 COG1414 IclR, Transcriptional regulator Transcription 110635433 Nonpathogen - protein of unknown function DUF883, ElaB Meso_3104 1 None None None 110636382 Common - histidine triad (HIT) protein Meso_4058 54 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 110633440 Common - putative hydrolase protein Meso_1086 37 COG3571 COG3571, Predicted hydrolase of the alpha/beta-hydrolase fold General function prediction only 110633241 Nonpathogen - hypothetical protein Meso_0884 1 None None None 110635850 Common - short-chain dehydrogenase/reductase SDR Meso_3522 230 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 110636386 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase Meso_4062 178 COG0756 Dut, dUTPase Nucleotide transport and metabolism 110634163 Common - Sporulation related Meso_1812 16 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 110635372 Common mdoD glucan biosynthesis protein D Meso_3043 50 COG3131 MdoG, Periplasmic glucans biosynthesis protein Inorganic ion transport and metabolism 110632851 Common - ABC-2 type transporter Meso_0491 24 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 110632889 Common - protein of unknown function DUF736 Meso_0529 27 COG5489 COG5489, Uncharacterized conserved protein Function unknown 110636389 Common - cytochrome d ubiquinol oxidase, subunit II Meso_4065 145 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 110634946 Nonpathogen - hypothetical protein Meso_2607 2 None None None 110636236 Common - hypothetical protein Meso_3912 21 None None None 110632684 Common - Bile acid:sodium symporter Meso_0323 125 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 110633892 Common - Mandelate racemase/muconate lactonizing enzyme-like Meso_1539 97 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 110634054 Common - transcription-repair coupling factor Meso_1702 219 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 110633832 Common - aminotransferase, class I and II Meso_1479 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 110634817 Common - cytochrome c oxidase, subunit III Meso_2476 52 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 110632632 Common fliR flagellar biosynthesis protein FliR Meso_0271 108 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 110633505 Common - Integral membrane protein TerC Meso_1152 84 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 110636328 Common - ABC-3 Meso_4004 171 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 110634632 Common - acriflavin resistance protein Meso_2286 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 110634767 Common - cytochrome d ubiquinol oxidase, subunit II Meso_2426 147 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 110633299 Common - DNA-directed RNA polymerase, omega subunit Meso_0945 114 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 110633064 Common - hypothetical protein Meso_0707 6 None None None 110634451 Common - outer membrane autotransporter barrel domain Meso_2102 93 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 110635759 Common - acetyl-CoA synthetase Meso_3431 214 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 110634220 Common - glutamine synthetase, catalytic region Meso_1870 223 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 110634816 Common - cytochrome c oxidase, subunit I Meso_2475 170 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 110632708 Common - FAD linked oxidase-like Meso_0347 64 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 110633940 Common - putative glucose/sorbosone dehydrogenase Meso_1588 73 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 110635783 Common nadD nicotinic acid mononucleotide adenyltransferase Meso_3455 151 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 110632976 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) Meso_0619 185 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 110633303 Common - signal peptidase I Meso_0949 210 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 110633597 Common - blue (type 1) copper domain Meso_1244 23 COG3794 PetE, Plastocyanin Energy production and conversion 110633039 Common - NADPH-dependent FMN reductase Meso_0682 126 COG0431 COG0431, Predicted flavoprotein General function prediction only 110636351 Common - hypothetical protein Meso_4027 51 COG0392 COG0392, Predicted integral membrane protein Function unknown 110635290 Common - ABC transporter related Meso_2961 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 110633796 Common - transport system permease protein Meso_1443 190 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 110633311 Common - RimK-like ATP-grasp Meso_0957 82 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 110635930 Common - hypothetical protein Meso_3604 8 COG2900 SlyX, Uncharacterized protein conserved in bacteria Function unknown 110633174 Nonpathogen - hypothetical protein Meso_0817 1 COG4809 COG4809, Archaeal ADP-dependent phosphofructokinase/glucokinase Carbohydrate transport and metabolism 110634411 Common - binding-protein-dependent transport systems inner membrane component Meso_2061 218 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110633688 Common - xanthine-guanine phosphoribosyltransferase Meso_1335 96 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 110636126 Nonpathogen - hypothetical protein Meso_3802 1 None None None 110635426 Common - hypothetical protein Meso_3097 28 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 110634693 Nonpathogen - Xanthosine triphosphate pyrophosphatase-like Meso_2349 28 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 110635354 Common - HhH-GPD Meso_3025 97 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 110634752 Common - transcriptional regulator, LysR family Meso_2411 120 COG0583 LysR, Transcriptional regulator Transcription 110634795 Common - transcriptional regulator, TetR family Meso_2454 55 COG1309 AcrR, Transcriptional regulator Transcription 110634540 Common - transcriptional regulator, ArsR family Meso_2191 97 COG0640 ArsR, Predicted transcriptional regulators Transcription 110633874 Common - surface antigen (D15) Meso_1521 143 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 110634606 Common - Thioredoxin domain Meso_2259 231 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 110633697 Common - DNA polymerase IV Meso_1344 186 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 110632577 Nonpathogen - hypothetical protein Meso_0215 1 None None None 110632450 Common - 5-aminolevulinate synthase Meso_0088 190 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 110633671 Common - 3-oxoacyl-(acyl carrier protein) synthase II Meso_1318 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110634568 Common - Recombinase Meso_2219 62 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 110633978 Common - dihydrolipoamide dehydrogenase Meso_1626 245 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 110635823 Common hisH imidazole glycerol phosphate synthase subunit HisH Meso_3495 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 110632876 Common - hypothetical protein Meso_0516 26 COG3843 VirD2, Type IV secretory pathway, VirD2 components (relaxase) Intracellular trafficking and secretion 110635738 Common - protein of unknown function DUF465 Meso_3410 32 COG5481 COG5481, Uncharacterized conserved small protein containing a coiled-coil domain Function unknown 110635297 Common - Mandelate racemase/muconate lactonizing enzyme-like Meso_2968 94 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 110635818 Common hslU ATP-dependent protease ATP-binding subunit Meso_3490 209 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 110634760 Common - peptidase M24 Meso_2419 148 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 110636252 Common nusA transcription elongation factor NusA Meso_3928 218 COG0195 NusA, Transcription elongation factor Transcription 110635331 Common - 3-demethylubiquinone-9 3-methyltransferase Meso_3002 115 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 110634362 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase Meso_2012 212 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 110633484 Common - hypothetical protein Meso_1131 12 None None None 110635668 Common - chorismate mutase Meso_3340 57 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 110635221 Common - hypothetical protein Meso_2888 21 None None None 110635101 Common - metallophosphoesterase Meso_2768 14 COG2129 COG2129, Predicted phosphoesterases, related to the Icc protein General function prediction only 110634984 Common - binding-protein-dependent transport systems inner membrane component Meso_2650 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110635493 Common - hypothetical protein Meso_3164 27 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 110634530 Common - hypothetical protein Meso_2181 33 None None None 110634624 Nonpathogen - hypothetical protein Meso_2278 2 COG3462 COG3462, Predicted membrane protein Function unknown 110633122 Common - A/G-specific adenine glycosylase Meso_0765 229 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 110635573 Common sdhA succinate dehydrogenase flavoprotein subunit Meso_3244 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 110636270 Common - 6-phosphogluconate dehydrogenase Meso_3946 186 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 110632651 Common - flagellar basal body-associated protein FliL Meso_0290 11 None None None 110633222 Common - putative monovalent cation/H+ antiporter subunit B Meso_0865 96 COG2111 MnhB, Multisubunit Na+/H+ antiporter, MnhB subunit Inorganic ion transport and metabolism 110633756 Common - peptidyl-prolyl cis-trans isomerase, cyclophilin type Meso_1403 196 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 110636287 Common - arginase Meso_3963 143 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 110633048 Common - hypothetical protein Meso_0691 20 COG4649 COG4649, Uncharacterized protein conserved in bacteria Function unknown 110635047 Common - transcriptional regulator, LysR family Meso_2713 144 COG0583 LysR, Transcriptional regulator Transcription 110635844 Common - protein of unknown function DUF892 Meso_3516 21 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 110633723 Common - heat shock protein DnaJ-like Meso_1370 24 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 110633273 Nonpathogen - hypothetical protein Meso_0919 1 None None None 110632919 Common - ABC transporter related Meso_0560 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 110634150 Common - protein of unknown function DUF815 Meso_1799 89 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 110632663 Common - protein of unknown function DUF1217 Meso_0302 20 None None None 110636397 Common - transcriptional regulator, TetR family Meso_4073 90 COG1309 AcrR, Transcriptional regulator Transcription 110635243 Common - major facilitator superfamily MFS_1 Meso_2913 175 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 110633182 Common - aldehyde dehydrogenase Meso_0825 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 110632564 Nonpathogen - hypothetical protein Meso_0202 1 None None None 110635565 Common - ammonium transporter Meso_3236 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 110632643 Common - flagellar hook-length control protein Meso_0282 10 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 110636243 Common - RNA modification enzyme, MiaB family Meso_3919 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 110634141 Common tig trigger factor Meso_1790 214 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 110634866 Common - luciferase-like Meso_2525 105 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 110632409 Common - conserved repeat domain Meso_0047 31 None None None 110636008 Common - Alcohol dehydrogenase GroES-like Meso_3683 203 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 110634879 Common - transcriptional regulator, AraC family Meso_2538 105 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 110635054 Common - molybdate ABC transporter, ATPase subunit Meso_2720 249 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 110632926 Common - FAD dependent oxidoreductase Meso_0567 104 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 110632400 Common - extracellular solute-binding protein, family 5 Meso_0038 213 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 110632691 Common - protein of unknown function DUF892 Meso_0330 27 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 110634601 Common - integral membrane protein-like Meso_2254 37 COG5473 COG5473, Predicted integral membrane protein Function unknown 110634867 Common - alpha/beta hydrolase fold Meso_2526 192 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 110635487 Nonpathogen - hypothetical protein Meso_3158 1 None None None 110634236 Common - phage head-tail adaptor, putative Meso_1886 9 COG5614 COG5614, Bacteriophage head-tail adaptor General function prediction only 110634034 Common - 30S ribosomal protein S7 Meso_1682 249 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 110635355 Common - glutamyl-Q tRNA(Asp) synthetase Meso_3026 247 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 110634842 Common - Radical SAM Meso_2501 55 COG4277 COG4277, Predicted DNA-binding protein with the Helix-hairpin-helix motif General function prediction only 110636302 Common - extracellular solute-binding protein, family 3 Meso_3978 171 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 110633527 Nonpathogen - hypothetical protein Meso_1174 1 None None None 110633305 Common era GTP-binding protein Era Meso_0951 230 COG1159 Era, GTPase General function prediction only 110633934 Common - DNA polymerase III subunit delta' Meso_1582 224 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 110634397 Common - hypothetical protein Meso_2047 88 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 110632780 Common hisG ATP phosphoribosyltransferase catalytic subunit Meso_0419 214 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 110632956 Common - methyl-accepting chemotaxis sensory transducer Meso_0599 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 110635658 Common - major facilitator superfamily MFS_1 Meso_3330 68 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 110635707 Common - transcriptional regulator, CarD family Meso_3379 83 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 110632530 Common - acetyl-CoA synthetase Meso_0168 203 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 110634437 Common - Methyltransferase type 11 Meso_2088 212 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 110635067 Common - keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase Meso_2733 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 110636062 Common - extracellular solute-binding protein, family 5 Meso_3737 197 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 110635360 Common - ATP--cobalamin adenosyltransferase Meso_3031 131 COG2096 COG2096, Uncharacterized conserved protein Function unknown 110636136 Common - protein of unknown function DUF159 Meso_3812 62 COG2135 COG2135, Uncharacterized conserved protein Function unknown 110633201 Common - aldehyde dehydrogenase Meso_0844 191 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 110634381 Common - 3-oxoacyl-(acyl carrier protein) synthase III Meso_2031 201 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 110634095 Common - phosphoserine phosphatase SerB Meso_1744 145 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 110634905 Common thiG thiazole synthase Meso_2564 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 110632934 Common - protein of unknown function DUF323 Meso_0576 94 COG1262 COG1262, Uncharacterized conserved protein Function unknown 110635224 Common - cytochrome c, class I Meso_2891 10 None None None 110635674 Common - protein of unknown function DUF1232 Meso_3346 24 COG3339 COG3339, Uncharacterized conserved protein Function unknown 110632732 Common - hypothetical protein Meso_0371 12 None None None 110633904 Common - protein of unknown function DUF1289 Meso_1551 41 COG3313 COG3313, Predicted Fe-S protein General function prediction only 110635456 Nonpathogen - hypothetical protein Meso_3127 2 None None None 110635978 Common - inner-membrane translocator Meso_3653 107 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 110632887 Common - hypothetical protein Meso_0527 13 None None None 110635394 Common aroB 3-dehydroquinate synthase Meso_3065 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 110635606 Common - acyl-CoA dehydrogenase-like Meso_3278 154 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 110633932 Common - peptidase S11, D-alanyl-D-alanine carboxypeptidase 1 Meso_1580 153 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 110634495 Nonpathogen - hypothetical protein Meso_2146 1 None None None 110633715 Common - metal-dependent hydrolase Meso_1362 97 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 110632653 Common - hypothetical protein Meso_0292 14 COG3334 COG3334, Uncharacterized conserved protein Function unknown 110635575 Common - succinate dehydrogenase, cytochrome b subunit Meso_3246 82 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 110633754 Common - Lysine exporter protein (LYSE/YGGA) Meso_1401 112 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 110632773 Common - alkylhydroperoxidase like protein, AhpD family Meso_0412 79 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 110632895 Common - probably methylase/helicase Meso_0535 25 None None None 110635258 Common - transcriptional regulator, MarR family Meso_2929 69 COG1846 MarR, Transcriptional regulators Transcription 110633863 Common - ABC transporter related Meso_1510 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 110635944 Common - Transketolase, central region Meso_3618 228 COG3958 COG3958, Transketolase, C-terminal subunit Carbohydrate transport and metabolism 110633612 Common - transcriptional regulator, MerR family Meso_1259 49 COG0789 SoxR, Predicted transcriptional regulators Transcription 110634700 Nonpathogen - Helix-turn-helix, type 11 Meso_2356 1 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 110633093 Common - hemolysin A Meso_0736 134 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 110635899 Common - HPr kinase Meso_3573 12 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 110633980 Common - branched-chain alpha-keto acid dehydrogenase subunit E2 Meso_1628 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 110636409 Common - cytochrome c, class I Meso_4085 57 COG3474 COG3474, Cytochrome c2 Energy production and conversion 110632624 Common - inner-membrane translocator Meso_0263 105 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 110633771 Common - putative phosphohistidine phosphatase, SixA Meso_1418 61 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 110632744 Nonpathogen - hypothetical protein Meso_0383 1 None None None 110633073 Common - FAD linked oxidase-like Meso_0716 200 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 110633184 Common - binding-protein-dependent transport systems inner membrane component Meso_0827 174 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 110635594 Common - contains weak similarity to RecA protein Meso_3265 13 COG4544 COG4544, Uncharacterized conserved protein Function unknown 110635715 Common - sulphate transporter Meso_3387 161 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 110632746 Nonpathogen - hypothetical protein Meso_0385 1 None None None 110636259 Common - polynucleotide phosphorylase/polyadenylase Meso_3935 240 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 110635308 Common - binding-protein-dependent transport systems inner membrane component Meso_2979 144 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 110635108 Nonpathogen - hypothetical protein Meso_2775 12 COG4641 COG4641, Uncharacterized protein conserved in bacteria Function unknown 110632838 Common - inner-membrane translocator Meso_0477 135 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 110635922 Common mepA penicillin-insensitive murein endopeptidase Meso_3596 41 COG3770 MepA, Murein endopeptidase Cell envelope biogenesis, outer membrane 110634003 Common - protease Do Meso_1651 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 110632566 Common - single-strand binding protein Meso_0204 209 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 110634659 Common - hypothetical protein Meso_2314 23 COG5639 COG5639, Uncharacterized conserved small protein Function unknown 110635165 Common - Transthyretin Meso_2832 63 COG2351 COG2351, Transthyretin-like protein General function prediction only 110635863 Common - cytochrome c oxidase, subunit I Meso_3535 166 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 110633589 Common - hypothetical protein Meso_1236 2 None None None 110634405 Common - dihydropyrimidine dehydrogenase Meso_2055 133 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 110634188 Common - putative sarcosine oxidase alpha subunit Meso_1838 31 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 110635432 Nonpathogen - hypothetical protein Meso_3103 1 None None None 110634379 Common - transcriptional regulator, ArsR family Meso_2029 187 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 110633018 Common - metallophosphoesterase Meso_0661 102 None None None 110634740 Nonpathogen - hypothetical protein Meso_2398 1 None None None 110636226 Common - short-chain dehydrogenase/reductase SDR Meso_3902 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 110634375 Common - glycoside hydrolase, family 25 Meso_2025 44 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 110632372 Common - GcrA cell cycle regulator Meso_0010 33 COG5352 COG5352, Uncharacterized protein conserved in bacteria Function unknown 110633546 Common - putative phage repressor Meso_1193 23 COG2932 COG2932, Predicted transcriptional regulator Transcription 110634535 Common - NUDIX hydrolase Meso_2186 42 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 110634838 Common - inner-membrane translocator Meso_2497 145 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 110634673 Common - hypothetical protein Meso_2328 13 None None None 110636414 Common - 2-polyprenylphenol 6-hydroxylase Meso_4090 184 COG0661 AarF, Predicted unusual protein kinase General function prediction only 110635879 Common - transcriptional regulator, GntR family Meso_3552 133 COG1802 GntR, Transcriptional regulators Transcription 110636082 Common - dihydroxy-acid dehydratase Meso_3757 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 110635348 Common - hypothetical protein Meso_3019 18 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 110636183 Common - Conjugal transfer protein TrbG/VirB9/CagX Meso_3859 52 COG3504 VirB9, Type IV secretory pathway, VirB9 components Intracellular trafficking and secretion 110632858 Common - transcriptional regulator, LysR family Meso_0498 184 COG0583 LysR, Transcriptional regulator Transcription 110633398 Common - gamma-glutamyltransferase Meso_1044 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 110632614 Common - transcriptional regulator, GntR family Meso_0253 221 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 110633987 Nonpathogen secG preprotein translocase subunit SecG Meso_1635 1 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 110634264 Nonpathogen - hypothetical protein Meso_1914 4 None None None 110633353 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Meso_0999 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 110633156 Common - polysaccharide deacetylase Meso_0799 111 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 110632804 Common - 2-amino-3-ketobutyrate coenzyme A ligase Meso_0443 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 110634479 Common clpS ATP-dependent Clp protease adaptor Meso_2130 119 COG2127 COG2127, Uncharacterized conserved protein Function unknown 110635016 Common - HupE/UreJ protein Meso_2682 41 COG2370 HupE, Hydrogenase/urease accessory protein Posttranslational modification, protein turnover, chaperones 110633133 Common - BioY protein Meso_0776 76 COG1268 BioY, Uncharacterized conserved protein General function prediction only 110633804 Common - nitrite reductase (NAD(P)H), large subunit Meso_1451 191 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 110633969 Common - multi-sensor signal transduction histidine kinase Meso_1617 221 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 110636421 Common - TadE-like Meso_4097 13 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 110635809 Common coaE dephospho-CoA kinase Meso_3481 209 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 110633191 Common - bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein Meso_0834 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 110635853 Common - Pyrrolo-quinoline quinone Meso_3525 58 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 110635800 Common trmE tRNA modification GTPase TrmE Meso_3472 227 COG0486 ThdF, Predicted GTPase General function prediction only 110635011 Common - glycogen branching enzyme Meso_2677 144 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 110634952 Nonpathogen - hypothetical protein Meso_2615 1 None None None 110635505 Common ruvB Holliday junction DNA helicase B Meso_3176 227 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 110633153 Common - transcriptional regulator, LuxR family Meso_0796 108 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 110634720 Common - xenobiotic compound monooxygenase, DszA family, A subunit Meso_2378 70 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 110632489 Common - peptidase M3A and M3B, thimet/oligopeptidase F Meso_0127 123 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 110634295 Common - amidohydrolase 2 Meso_1945 30 COG3618 COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 110632418 Common - hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta subunit Meso_0056 148 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 110633530 Common - hypothetical protein Meso_1177 12 None None None 110635295 Common - short-chain dehydrogenase/reductase SDR Meso_2966 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110632787 Common - hypothetical protein Meso_0426 11 None None None 110634213 Common - binding-protein-dependent transport systems inner membrane component Meso_1863 182 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 110633465 Common - cystathionine beta-lyase Meso_1112 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 110632495 Common - periplasmic binding protein Meso_0133 69 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 110635318 Nonpathogen - hypothetical protein Meso_2989 1 None None None 110635689 Nonpathogen - Heme exporter protein D (CcmD) Meso_3361 1 None None None 110635710 Common - hypothetical protein Meso_3382 12 None None None 110635954 Common - protein of unknown function DUF1338 Meso_3628 23 COG5383 COG5383, Uncharacterized protein conserved in bacteria Function unknown 110635460 Common - extracellular solute-binding protein, family 5 Meso_3131 213 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 110632703 Nonpathogen - hypothetical protein Meso_0342 1 None None None 110633543 Nonpathogen - hypothetical protein Meso_1190 1 None None None 110632829 Common - membrane protein-like Meso_0468 10 COG4329 COG4329, Predicted membrane protein Function unknown 110634462 Common - transcriptional regulator, AsnC family Meso_2113 159 COG1522 Lrp, Transcriptional regulators Transcription 110633491 Common - 6,7-dimethyl-8-ribityllumazine synthase Meso_1138 215 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 110635969 Common - Twin-arginine translocation pathway signal Meso_3643 195 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 110632472 Common - type III secretion system protein Meso_0110 128 COG4790 EscR, Type III secretory pathway, component EscR Intracellular trafficking and secretion 110636026 Common - Alcohol dehydrogenase GroES-like Meso_3701 202 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 110635183 Common - ABC-3 Meso_2850 153 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 110635523 Common - Integral membrane protein TerC Meso_3194 105 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 110635892 Nonpathogen - hypothetical protein Meso_3566 5 None None None 110634889 Common - protein of unknown function DUF917 Meso_2548 24 COG3535 COG3535, Uncharacterized conserved protein Function unknown 110635405 Common - Activator of Hsp90 ATPase-like Meso_3076 30 COG3832 COG3832, Uncharacterized conserved protein Function unknown 110632880 Common - hypothetical protein Meso_0520 23 None None None 110632546 Common - protein of unknown function DUF1127 Meso_0184 2 None None None 110636086 Common - Dak kinase Meso_3761 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 110636048 Nonpathogen - hypothetical protein Meso_3723 1 None None None 110635792 Common - oxidoreductase FAD/NAD(P)-binding Meso_3464 104 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 110634008 Common rpsM 30S ribosomal protein S13 Meso_1656 240 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 110635273 Common - ThiJ/PfpI Meso_2944 69 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 110633769 Common - hypothetical protein Meso_1416 43 COG3768 COG3768, Predicted membrane protein Function unknown 110633971 Common - signal transduction histidine kinase, nitrogen specific, NtrB Meso_1619 222 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 110633594 Nonpathogen - hypothetical protein Meso_1241 1 None None None 110636334 Common - hypothetical protein Meso_4010 98 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 110635135 Common - protein of unknown function DUF992 Meso_2802 12 None None None 110634506 Common - 50S ribosomal protein L25/general stress protein Ctc Meso_2157 191 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 110634576 Common - GCN5-related N-acetyltransferase Meso_2228 150 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 110634010 Common secY preprotein translocase subunit SecY Meso_1658 223 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 110633962 Common - amidohydrolase 2 Meso_1610 49 COG3618 COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 110634851 Nonpathogen - integral membrane protein Meso_2510 2 None None None 110635501 Common - TolA, TolA protein Meso_3172 21 COG5373 COG5373, Predicted membrane protein Function unknown 110635945 Common - short-chain dehydrogenase/reductase SDR Meso_3619 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110634808 Common - diguanylate cyclase Meso_2467 176 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 110635247 Common - protein of unknown function DUF112, transmembrane Meso_2918 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 110636111 Common - protein of unknown function DUF395, YeeE/YedE Meso_3786 51 COG2391 COG2391, Predicted transporter component General function prediction only 110636315 Common - nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin-like Meso_3991 164 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 110634124 Common - DEAD/DEAH box helicase-like Meso_1773 240 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 110636146 Common - Antirestriction protein Meso_3822 17 None None None 110632930 Common - Twin-arginine translocation pathway signal Meso_0572 61 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 110633825 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Meso_1472 35 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 110635388 Common - SirA-like Meso_3059 98 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 110632775 Common - protein of unknown function DUF1468 Meso_0414 4 None None None 110634963 Common - argininosuccinate lyase Meso_2629 220 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 110634519 Common - hypothetical protein Meso_2170 9 None None None 110634082 Common - alpha/beta hydrolase fold Meso_1731 111 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 110635558 Common - GCN5-related N-acetyltransferase Meso_3229 71 COG0456 RimI, Acetyltransferases General function prediction only 110635584 Common - protein of unknown function DUF1036 Meso_3255 18 COG5480 COG5480, Predicted integral membrane protein Function unknown 110633748 Common - conserved hypothetical glutathione S-transferase like protein Meso_1395 49 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 110634206 Common - binding-protein-dependent transport systems inner membrane component Meso_1856 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110634666 Common - ATPas Meso_2321 61 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 110636054 Common - binding-protein-dependent transport systems inner membrane component Meso_3729 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110635527 Common - protein of unknown function DUF1332 Meso_3198 15 COG4103 COG4103, Uncharacterized protein conserved in bacteria Function unknown 110635143 Common - diguanylate cyclase/phosphodiesterase Meso_2810 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 110634489 Common - branched-chain amino acid aminotransferase Meso_2140 217 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 110635465 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Meso_3136 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 110633007 Common - ketal pyruvate transferase protein Meso_0650 12 None None None 110632444 Nonpathogen - hypothetical protein Meso_0082 1 None None None 110632820 Common - extracellular solute-binding protein, family 5 Meso_0459 199 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 110632734 Common - glutamate--cysteine ligase Meso_0373 53 COG3572 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 110634359 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase Meso_2009 210 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 110635473 Nonpathogen - hypothetical protein Meso_3144 1 None None None 110635591 Common - peptidase M48, Ste24p Meso_3262 131 COG4784 COG4784, Putative Zn-dependent protease General function prediction only 110635275 Common - 3-hydroxyacyl-CoA dehydrogenase, NAD-binding Meso_2946 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 110635761 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Meso_3433 27 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 110633337 Common - amidophosphoribosyltransferase Meso_0983 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 110635914 Common - SMP-30/Gluconolaconase/LRE-like region Meso_3588 73 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 110635541 Common - putative translaldolase Meso_3212 154 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 110633408 Common - short-chain dehydrogenase/reductase SDR Meso_1054 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110633605 Nonpathogen - hypothetical protein Meso_1252 5 None None None 110634927 Nonpathogen - hypothetical protein Meso_2586 3 None None None 110634177 Common - Exopolysaccharide synthesis, ExoD Meso_1827 33 COG3932 COG3932, Uncharacterized ABC-type transport system, permease components General function prediction only 110632463 Nonpathogen - Forkhead-associated Meso_0101 1 None None None 110633634 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase Meso_1281 161 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 110633539 Common - heat shock protein DnaJ-like Meso_1186 5 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 110634747 Common - beta-lactamase-like Meso_2405 93 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 110634684 Common - hypothetical protein Meso_2340 7 None None None 110632964 Common - TadE-like Meso_0607 6 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 110635614 Common - L-carnitine dehydratase/bile acid-inducible protein F Meso_3286 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 110634017 Common rpsN 30S ribosomal protein S14 Meso_1665 205 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 110634480 Common - hypothetical protein Meso_2131 4 None None None 110634671 Common - CopG-like DNA-binding Meso_2326 23 None None None 110636296 Common - Shikimate dehydrogenase substrate binding-like Meso_3972 194 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 110635804 Common hemE uroporphyrinogen decarboxylase Meso_3476 180 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 110632766 Common - Rhodanese-like Meso_0405 144 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 110633656 Common - Entericidin EcnAB Meso_1303 4 None None None 110634660 Common - conjugation TrbI-like protein Meso_2315 58 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 110634981 Common - Hydantoinase/oxoprolinase Meso_2647 117 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 110632604 Common - hypothetical protein Meso_0243 10 COG3179 COG3179, Predicted chitinase General function prediction only 110634284 Common - CoA-binding Meso_1934 140 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 110633411 Common - HpcH/HpaI aldolase Meso_1057 74 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 110635025 Common - Nucleotidyl transferase Meso_2691 102 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 110632427 Common - binding-protein-dependent transport systems inner membrane component Meso_0065 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110633344 Common - single-stranded-DNA-specific exonuclease RecJ Meso_0990 194 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 110634584 Common - putative phosphoketolase Meso_2236 65 COG3957 COG3957, Phosphoketolase Carbohydrate transport and metabolism 110634166 Common - iron-sulfur cluster assembly accessory protein Meso_1815 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 110632517 Nonpathogen - hypothetical protein Meso_0155 1 None None None 110632430 Common - protein of unknown function DUF924 Meso_0068 63 COG3803 COG3803, Uncharacterized protein conserved in bacteria Function unknown 110635877 Common - Mandelate racemase/muconate lactonizing enzyme-like Meso_3550 132 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 110635204 Common - modification methylase, HemK family Meso_2871 219 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 110634115 Common - hypothetical protein Meso_1764 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 110633619 Common alaS alanyl-tRNA synthetase Meso_1266 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 110633646 Common - protein of unknown function DUF182 Meso_1293 105 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 110632480 Common - NolW-like Meso_0118 20 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 110635536 Common - isochorismatase hydrolase Meso_3207 131 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 110633844 Common - ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member-like Meso_1491 109 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 110635237 Nonpathogen - hypothetical protein Meso_2907 1 None None None 110634642 Common - extracellular solute-binding protein, family 1 Meso_2297 90 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 110635994 Common - OstA-like protein Meso_3669 37 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 110633627 Common - BioY protein Meso_1274 28 COG1268 BioY, Uncharacterized conserved protein General function prediction only 110634970 Common - binding-protein-dependent transport systems inner membrane component Meso_2636 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 110634829 Common - transcriptional regulator, AraC family Meso_2488 101 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 110633297 Common - Uracil-DNA glycosylase superfamily Meso_0943 71 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 110635698 Common - outer membrane autotransporter barrel domain Meso_3370 46 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 110634777 Common - ABC transporter related Meso_2436 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 110633208 Common - L-asparaginase II Meso_0851 46 COG4448 AnsA, L-asparaginase II Amino acid transport and metabolism 110633216 Common - ErfK/YbiS/YcfS/YnhG Meso_0859 83 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 110635150 Nonpathogen - hypothetical protein Meso_2817 1 None None None 110634512 Common - adenine phosphoribosyltransferase Meso_2163 195 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 110633478 Common - hypothetical protein Meso_1125 16 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 110632521 Common - glucose-6-phosphate 1-dehydrogenase Meso_0159 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 110632833 Common - (2Fe-2S)-binding Meso_0472 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 110636127 Nonpathogen - hypothetical protein Meso_3803 1 None None None 110636152 Common - probably methylase/helicase Meso_3828 21 COG1041 COG1041, Predicted DNA modification methylase DNA replication, recombination, and repair 110632584 Nonpathogen - hypothetical protein Meso_0223 3 None None None 110632878 Common - protein of unknown function DUF736 Meso_0518 26 COG5489 COG5489, Uncharacterized conserved protein Function unknown 110632812 Common - Aldose 1-epimerase Meso_0451 96 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 110635686 Common - heme exporter protein CcmA Meso_3358 249 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 110632506 Common - cytochrome B561 Meso_0144 80 COG3038 CybB, Cytochrome B561 Energy production and conversion 110635633 Common - aldehyde dehydrogenase Meso_3305 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 110636107 Common - short-chain dehydrogenase/reductase SDR Meso_3782 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 110636219 Common - protein of unknown function DUF305 Meso_3895 50 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 110635230 Nonpathogen - hypothetical protein Meso_2900 1 COG3909 COG3909, Cytochrome c556 Energy production and conversion 110632576 Nonpathogen - hypothetical protein Meso_0214 1 None None None 110632861 Common - Conjugal transfer protein TrbG/VirB9/CagX Meso_0501 52 COG3504 VirB9, Type IV secretory pathway, VirB9 components Intracellular trafficking and secretion 110636016 Common - Amylo-alpha-1,6-glucosidase Meso_3691 54 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 110633662 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Meso_1309 39 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 110633326 Common - Peptidoglycan-binding LysM Meso_0972 20 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 110636120 Common - hypothetical protein Meso_3795 34 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 110634138 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Meso_1787 222 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones