Lawsonia intracellularis PHE/MN1-00, complete genome NC_008011 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 94986768 Common thiE Thiamine monophosphate synthase LI0324 208 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 94987112 Common ahcY S-adenosyl-L-homocysteine hydrolase LI0670 177 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 94987172 Common ugd predicted UDP-glucose 6-dehydrogenase LI0730 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 94986962 Common - hypothetical protein LI0519 151 COG1610 COG1610, Uncharacterized conserved protein Function unknown 94986588 Pathogen - NA LI0143 1 None None None 94986622 Common - NA LI0178 3 None None None 94987448 Common pnpA polynucleotide phosphorylase/polyadenylase LI1006 235 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 94986963 Pathogen - NA LI0520 2 None None None 94987601 Pathogen - NA LI1159 1 None None None 94986457 Common - NA LI0012 4 None None None 94987514 Common trmE tRNA modification GTPase TrmE LI1072 226 COG0486 ThdF, Predicted GTPase General function prediction only 94987398 Common ccmF Cytochrome c biogenesis factor LI0956 158 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 94987540 Common ftsI cell division protein FtsI/penicillin-binding protein 2 LI1098 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 94986595 Common - hypothetical protein LI0150 3 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 94986808 Common gph predicted phosphatases LI0364 174 COG0546 Gph, Predicted phosphatases General function prediction only 94987130 Common - Outer membrane protein LI0688 148 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 94986494 Common yajC Preprotein translocase subunit YajC LI0049 157 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 94987488 Common - ABC-type transport system involved in resistance to organic solvents, ATPase component LI1046 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 94987405 Common rplB 50S ribosomal protein L2 LI0963 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 94987382 Common yqiE ADP-ribose pyrophosphatase LI0940 118 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 94986545 Common - hypothetical protein LI0100 12 None None None 94986941 Common livM branched chain amino acid ABC transporter, permease protein LI0498 139 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 94987465 Common amiA N-acetylmuramoyl-L-alanine amidase LI1023 178 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 94987410 Common rpsQ 30S ribosomal protein S17 LI0968 231 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 94987419 Common secY preprotein translocase subunit SecY LI0977 224 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 94987441 Common - hypothetical protein LI0999 5 COG4319 COG4319, Ketosteroid isomerase homolog Function unknown 94986471 Common birA Biotin-(acetyl-CoA carboxylase) ligase LI0026 132 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 94986915 Common - predicted permease LI0472 118 COG0628 PerM, Predicted permease General function prediction only 94987226 Common gyrA Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit LI0784 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 94986552 Common - predicted permeases LI0107 30 COG0679 COG0679, Predicted permeases General function prediction only 94987534 Common - Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains LI1092 171 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 94987010 Common - Flagellar hook-length control protein LI0568 14 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 94987578 Common - hypothetical protein LI1136 2 COG2203 FhlA, FOG: GAF domain Signal transduction mechanisms 94986532 Common argD Ornithine/acetylornithine aminotransferase LI0087 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 94987057 Common - hypothetical protein LI0615 6 None None None 94987063 Common - nucleoside-diphosphate-sugar epimerases LI0621 213 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 94987509 Common - Cobalamin biosynthesis protein CbiK, Co2+ chelatase LI1067 24 COG4822 CbiK, Cobalamin biosynthesis protein CbiK, Co2+ chelatase Coenzyme metabolism 94987093 Common nadh Rhodanese-related sulfurtransferase LI0651 236 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 94987597 Common - NA LI1155 2 None None None 94987552 Common - hypothetical protein LI1110 46 COG2954 COG2954, Uncharacterized protein conserved in bacteria Function unknown 94987304 Common - NA LI0862 3 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 94986923 Common - esterase MesA LI0480 114 COG2845 COG2845, Uncharacterized protein conserved in bacteria Function unknown 94986617 Common - prophage DLP12 integrase LI0173 207 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 94986813 Common fbp fructose-1,6-bisphosphatase LI0369 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 94987492 Common - predicted metal-dependent phosphoesterases (PHP family) LI1050 113 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 94987311 Common - ABC-type multidrug transport system, ATPase and permease components LI0869 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 94987041 Common panF sodium/panthothenate symporter LI0599 183 COG4145 PanF, Na+/panthothenate symporter Coenzyme metabolism 94986556 Common - Site-specific recombinase XerC LI0111 228 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 94987462 Common fabZ (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase LI1020 188 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 94987359 Common - hypothetical protein LI0917 179 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 94987336 Common himD Bacterial nucleoid DNA-binding protein LI0894 206 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 94986448 Pathogen - NA LI0003 1 None None None 94986528 Common kpsF FOG: CBS domain LI0083 163 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 94986485 Pathogen - NA LI0040 1 None None None 94986743 Common glyS Glycyl-tRNA synthetase, beta subunit LI0299 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 94987612 Common cheW Chemotaxis signal transduction protein LI1170 131 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 94986696 Common - hypothetical protein LI0252 12 None None None 94986748 Common - Parvulin-like peptidyl-prolyl isomerase LI0304 15 None None None 94986635 Common - hypothetical protein LI0191 2 COG4856 COG4856, Uncharacterized protein conserved in bacteria Function unknown 94987376 Common nusG transcription antiterminator LI0934 215 COG0250 NusG, Transcription antiterminator Transcription 94987026 Common - hypothetical protein LI0584 2 COG1166 SpeA, Arginine decarboxylase (spermidine biosynthesis) Amino acid transport and metabolism 94987330 Common - Universal stress protein UspA and related nucleotide-binding proteins LI0888 79 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 94986818 Common - ATPases involved in chromosome partitioning LI0374 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 94987560 Common - hypothetical protein LI1118 45 COG3494 COG3494, Uncharacterized protein conserved in bacteria Function unknown 94986910 Common cynT carbonic anhydrase LI0467 150 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 94987005 Common - hypothetical protein LI0563 2 None None None 94987500 Common atpC F0F1-type ATP synthase, subunit c LI1058 48 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 94986610 Common ppiB Peptidyl-prolyl cis-trans isomerase (rotamase)-cyclophilin family LI0166 199 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 94986878 Common aspC L,L-diaminopimelate aminotransferase LI0435 216 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 94987215 Common kefC Kef-type K+ transport systems, membrane components LI0773 214 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 94986580 Common - hypothetical protein LI0135 21 COG4641 COG4641, Uncharacterized protein conserved in bacteria Function unknown 94986871 Common putP probable sodium-dependent transporter LI0428 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 94986462 Common ubiE Methylase involved in ubiquinone/menaquinone biosynthesis LI0017 196 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 94987008 Common flgE Flagellar hook protein FlgE LI0566 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 94987621 Common cbiO ABC-type cobalt transport system, ATPase component LI1179 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 94986513 Common - GTPase EngB LI0068 194 COG0218 COG0218, Predicted GTPase General function prediction only 94986714 Common ygcA 23S rRNA methylase LI0270 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 94987618 Common - nitroreductase LI1176 60 COG0778 NfnB, Nitroreductase Energy production and conversion 94986594 Common radC DNA repair proteins LI0149 177 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 94987290 Common gidA tRNA (uracil-5-)-methyltransferase Gid LI0848 105 COG1206 Gid, NAD(FAD)-utilizing enzyme possibly involved in translation Translation, ribosomal structure and biogenesis 94986681 Common - Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases LI0237 102 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 94987332 Pathogen - NA LI0890 1 COG3765 WzzB, Chain length determinant protein Cell envelope biogenesis, outer membrane 94987233 Common porB ferredoxin oxidoreductases, beta subunit LI0791 110 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 94987221 Common cutA divalent cation tolerance protein, probable LI0779 120 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 94987242 Common - hypothetical protein LI0800 170 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 94987116 Common - hypothetical protein LI0674 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 94987208 Common fmt Methionyl-tRNA formyltransferase LI0766 218 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 94987266 Common - Glycosyltransferase LI0824 146 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 94986846 Common atpC F0F1-type ATP synthase, subunit c LI0402 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 94987583 Common cheW Chemotaxis signal transduction protein LI1141 92 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 94987047 Common - hypothetical protein LI0605 37 COG1814 COG1814, Uncharacterized membrane protein Function unknown 94987499 Common atpA F0F1-type ATP synthase, subunit a LI1057 204 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 94986855 Common trpB tryptophan synthase subunit beta LI0411 224 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 94987191 Common - flagellar assembly protein FliW LI0749 87 COG1699 COG1699, Uncharacterized protein conserved in bacteria Function unknown 94986721 Common - hypothetical protein LI0277 2 None None None 94986521 Common - sugar ABC transporter, ATP-binding protein LI0076 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 94986779 Common livF branched chain amino acid ABC transporter, ATP-binding protein LI0335 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 94986836 Common mreB Actin-like ATPase involved in cell morphogenesis LI0392 234 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 94987407 Common rplV 50S ribosomal protein L22 LI0965 230 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 94987327 Common - Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases LI0885 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 94986786 Common leuB predicted Rossmann fold nucleotide-binding protein LI0342 118 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 94986663 Common tkt transketolase LI0219 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 94986944 Common hppA membrane-bound proton-translocating pyrophosphatase LI0501 98 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 94986792 Common flgE Flagellar hook protein FlgE LI0348 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 94986952 Common - Carbon starvation protein, predicted membrane protein LI0509 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 94987201 Common menA hypothetical protein LI0759 90 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 94986866 Pathogen - hypothetical protein LI0422 2 COG0429 COG0429, Predicted hydrolase of the alpha/beta-hydrolase fold General function prediction only 94987031 Common - Sec-independent protein secretion pathway components LI0589 5 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 94987019 Common - dTDP-glucose pyrophosphorylase LI0577 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 94987457 Common gmpA phosphoglyceromutase LI1015 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 94986986 Common - NA LI0544 2 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 94987452 Common gmhA phosphoheptose isomerase LI1010 121 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 94986651 Common nirD transcriptional regulators LI0207 51 COG1522 Lrp, Transcriptional regulators Transcription 94986667 Common - predicted endonuclease distantly related to archaeal Holliday junction resolvase LI0223 114 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 94987192 Common - hypothetical protein LI0750 193 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 94987052 Pathogen - NA LI0610 1 None None None 94987521 Common hydG Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains LI1079 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 94986515 Pathogen - NA LI0070 1 None None None 94987450 Common - hypothetical protein LI1008 12 None None None 94986561 Common - FOG: TPR repeat LI0116 7 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 94987340 Common tatD Mg-dependent DNase LI0898 236 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 94986999 Common bacA uncharacterized bacitracin resistance protein LI0557 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 94986992 Common yscT Type III secretion component protein SctT LI0550 111 COG4791 EscT, Type III secretory pathway, component EscT Intracellular trafficking and secretion 94987096 Common topA Zn-finger domain associated with topoisomerase type I LI0654 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 94987080 Common - NA LI0638 4 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 94987569 Common - Na+-driven multidrug efflux pump LI1127 131 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 94986930 Common motB Flagellar motor protein LI0487 153 COG1360 MotB, Flagellar motor protein Cell motility and secretion 94986538 Common - hypothetical protein LI0093 4 None None None 94986975 Common - transcription elongation factor LI0533 91 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 94986672 Common glpX fructose 1,6-bisphosphatase II LI0228 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 94986624 Pathogen - NA LI0180 1 None None None 94986824 Common - predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis LI0380 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 94987434 Pathogen - NA LI0992 1 None None None 94987155 Common pyrDII 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases LI0713 76 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 94987217 Common trkH Trk-type K+ transport systems, membrane components LI0775 121 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 94986774 Common - putative glycosyltransferase LI0330 195 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 94987105 Pathogen - NA LI0663 1 None None None 94987424 Common rpoA DNA-directed RNA polymerase subunit alpha LI0982 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 94986935 Common - Single-stranded DNA-binding protein LI0492 214 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 94986861 Common - ABC transporter ATP-binding protein LI0417 249 COG1101 PhnK, ABC-type uncharacterized transport system, ATPase component General function prediction only 94986640 Common - putative transport protein LI0196 57 COG2985 COG2985, Predicted permease General function prediction only 94986605 Common fabG 3-oxoacyl-[acyl-carrier protein] reductase LI0161 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 94987276 Common - hypothetical protein LI0834 6 COG5566 COG5566, Uncharacterized conserved protein Function unknown 94987396 Common - ABC-type transport system involved in cytochrome c biogenesis, permease component LI0954 3 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 94987389 Common - cell wall-associated hydrolases (invasion-associated proteins) LI0947 130 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 94986504 Common - hypothetical protein LI0059 25 COG4803 COG4803, Predicted membrane protein Function unknown 94986759 Common - predicted CoA-binding protein LI0315 116 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 94987070 Common mutL DNA mismatch repair enzyme (predicted ATPase) LI0628 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 94986632 Common ftsH ATP-dependent Zn proteases LI0188 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 94986492 Common secF preprotein translocase subunit SecF LI0047 201 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 94986644 Common purH AICAR transformylase/IMP cyclohydrolase PurH LI0200 218 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 94986568 Common lacA maltose O-acetyltransferase LI0123 198 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 94986917 Common - tellurite resistance LI0474 22 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 94986831 Common - predicted membrane-associated Zn-dependent proteases 1 LI0387 215 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 94986811 Common trxA Thiol-disulfide isomerase and thioredoxins LI0367 234 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 94986973 Common flhB flagellar biosynthesis protein FlhB LI0531 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 94987550 Common ftsA cell division protein FtsA LI1108 187 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 94986798 Common recQ Replicative DNA helicase LI0354 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 94987295 Common - predicted redox protein, regulator of disulfide bond formation LI0853 11 None None None 94987474 Common - hypothetical protein LI1032 5 None None None 94987368 Common mdoB hypothetical protein LI0926 51 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 94986891 Common - Zn-ribbon protein, possibly nucleic acid-binding LI0448 34 COG1579 COG1579, Zn-ribbon protein, possibly nucleic acid-binding General function prediction only 94987033 Common guaB IMP dehydrogenase/GMP reductase LI0591 240 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 94987166 Common - predicted thioesterase LI0724 132 COG0824 FcbC, Predicted thioesterase General function prediction only 94987228 Common dnaN DNA polymerase sliding clamp subunit (PCNA homolog) LI0786 201 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 94987547 Common murC UDP-N-acetylmuramate-alanine ligase LI1105 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 94986838 Common - hypothetical protein LI0394 2 None None None 94986984 Common - NA LI0542 2 None None None 94987619 Common - excinuclease ABC, A subunit LI1177 243 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 94987161 Common - ABC-type amino acid transport system, permease component LI0719 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 94987446 Common - predicted ATPase or kinase LI1004 127 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 94987086 Common era GTP-binding protein Era LI0644 222 COG1159 Era, GTPase General function prediction only 94986655 Common fliD Flagellar capping protein LI0211 45 COG1345 FliD, Flagellar capping protein Cell motility and secretion 94987174 Common hslV ATP-dependent protease peptidase subunit LI0732 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 94986548 Common - hypothetical protein LI0103 2 None None None 94987507 Common rfbD dTDP-4-dehydrorhamnose reductase LI1065 170 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 94987512 Common yidC Preprotein translocase subunit YidC LI1070 214 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 94986711 Common - NA LI0267 2 None None None 94987043 Common - voltage-gated chloride channel family protein LI0601 131 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 94986698 Common - hypothetical protein LI0254 14 None None None 94986479 Common alr alanine racemase, catabolic LI0034 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 94986965 Common - Glycosyltransferase LI0522 12 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 94986639 Common - SAM-dependent methyltransferases LI0195 28 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 94986597 Common leuS leucyl-tRNA synthetase LI0152 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 94987121 Common - Xanthosine triphosphate pyrophosphatase LI0679 235 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 94986960 Common rpoD DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) LI0517 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 94987271 Common potA putrescine/spermidine ABC transporter ATPase protein LI0829 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 94987109 Pathogen - NA LI0667 1 None None None 94987393 Common asd Aspartate-semialdehyde dehydrogenase LI0951 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 94987283 Common - putative invasin LI0841 24 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 94987532 Common - predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain LI1090 67 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 94986908 Common - hypothetical protein LI0465 5 None None None 94987559 Common cheV Chemotaxis signal transduction protein LI1117 153 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 94986487 Pathogen - NA LI0042 1 None None None 94987069 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase LI0627 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 94987625 Common metG methionyl-tRNA synthetase LI1183 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 94986959 Common purL phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain LI0516 233 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 94986816 Common - hypothetical protein LI0372 2 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 94987374 Common rplA 50S ribosomal protein L1 LI0932 231 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 94986637 Common galU UDP-glucose pyrophosphorylase LI0193 233 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 94986772 Common - hypothetical protein LI0328 2 None None None 94986746 Common - hypothetical protein LI0302 37 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 94986510 Common - Outer membrane lipoprotein-sorting protein LI0065 15 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 94986501 Common - nitrate ABC transporter, permease protein (nrtB-1) LI0056 183 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 94986706 Common - Amino acid transporters LI0262 74 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 94986799 Common - rRNA methylases LI0355 183 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 94986741 Pathogen - NA LI0297 1 None None None 94987021 Common mutT NTP pyrophosphohydrolases including oxidative damage repair enzymes LI0579 161 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 94986554 Common - hypothetical protein LI0109 97 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 94987249 Common menB naphthoate synthase LI0807 179 COG0447 MenB, Dihydroxynaphthoic acid synthase Coenzyme metabolism 94986876 Common dsbD uncharacterized protein predicted to be involved in C-type cytochrome biogenesis LI0433 130 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 94987571 Common glnQ ABC-type polar amino acid transport system, ATPase component LI1129 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 94986717 Common - Desulfoferrodoxin LI0273 28 COG2033 COG2033, Desulfoferrodoxin Energy production and conversion 94986950 Common - hypothetical protein LI0507 6 None None None 94987467 Common lolD ABC-type transport system, involved in lipoprotein release, permease component LI1025 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 94986519 Common - Rhodanese-related sulfurtransferase LI0074 9 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 94987412 Common rplX 50S ribosomal protein L24 LI0970 211 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 94986450 Common sodC superoxide dismutase precursor (Cu-Zn) LI0005 87 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 94987567 Common copA copper-translocating P-type ATPase LI1125 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 94986683 Common - site-specific recombinase LI0239 227 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 94987464 Common - Outer membrane protein LI1022 53 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 94986649 Common hemB delta-aminolevulinic acid dehydratase LI0205 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 94986558 Common engA GTP-binding protein EngA LI0113 229 COG1160 COG1160, Predicted GTPases General function prediction only 94987012 Common fliC Flagellin and related hook-associated proteins LI0570 107 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 94987357 Common livE Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase LI0915 218 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 94986585 Common - predicted glycosyltransferases LI0140 112 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 94987361 Common - Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster LI0919 4 None None None 94986723 Common pta phosphate acetyltransferase LI0279 180 COG0280 Pta, Phosphotransacetylase Energy production and conversion 94987185 Common flgH flagellar basal body L-ring protein LI0743 96 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 94986857 Common trpC_2 Probable indole-3-glycerol phosphate synthase protein LI0413 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 94986895 Common kdsA 2-dehydro-3-deoxyphosphooctonate aldolase LI0452 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 94987095 Common - Zn-dependent protease with chaperone function LI0653 130 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 94987247 Common - Hypothetical protein yjiH LI0805 11 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 94986851 Common - Geranylgeranyl pyrophosphate synthase LI0407 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 94986736 Common - Svh LI0292 51 COG2173 DdpX, D-alanyl-D-alanine dipeptidase Cell envelope biogenesis, outer membrane 94986777 Common argB Acetylglutamate kinase LI0333 219 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 94986822 Common tsf elongation factor Ts LI0378 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 94987267 Common - Lipid A core-O-antigen ligase and related enzymes LI0825 2 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 94986814 Common - hypothetical protein LI0370 2 None None None 94987153 Common - uncharacterized membrane protein, required for colicin V production LI0711 2 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 94987003 Common - predicted hydrolase of the metallo-beta-lactamase superfamily LI0561 154 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 94987103 Common glmS Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains LI0661 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 94986536 Common eno Enolase (2-phosphoglycerate dehydratase) LI0091 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 94986661 Common - predicted transcriptional regulators LI0217 105 COG0789 SoxR, Predicted transcriptional regulators Transcription 94986828 Common yaeS Undecaprenyl pyrophosphate synthase LI0384 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 94987149 Common hypF Hydrogenase maturation factor LI0707 110 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 94986887 Common - Glycosyltransferase LI0444 209 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 94987616 Common mltC membrane-bound lytic murein transglycosylase C (MltC) LI1174 105 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 94986989 Common - NA LI0547 3 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 94986460 Common upp Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase LI0015 109 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 94987623 Common alaS Alanyl-tRNA synthetase LI1181 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 94986848 Common atpA ATP synthase epsilon chain (ATP synthase F1 sector epsilon subunit) LI0404 184 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 94986726 Common kdtB phosphopantetheine adenylyltransferase LI0282 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 94987481 Pathogen - NA LI1039 1 None None None 94987436 Common acrB acriflavin resistance protein D LI0994 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 94987206 Common gapA Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase LI0764 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 94986731 Common recD ATP-dependent exoDNAse (exonuclease V), alpha subunit-helicase superfamily I member LI0287 159 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 94986563 Common purN phosphoribosylglycinamide formyltransferase LI0118 221 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 94987023 Common - hypothetical protein LI0581 2 None None None 94987607 Common - NA LI1165 2 None None None 94987549 Common ftsQ cell division septal protein LI1107 15 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 94987349 Common nirH transcriptional regulators LI0907 48 COG1522 Lrp, Transcriptional regulators Transcription 94986670 Common yjjK putative ABC transporter ATP-binding protein LI0226 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 94987177 Common ychB 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase LI0735 97 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 94986757 Common recJ Single-stranded DNA-specific exonuclease LI0313 196 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 94987585 Common cheA_1 Chemotaxis protein histidine kinase and related kinases LI1143 144 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 94987064 Common obgE GTPase ObgE LI0622 249 COG0536 Obg, Predicted GTPase General function prediction only 94986677 Common - ABC-type transport system involved in resistance to organic solvents, periplasmic component LI0233 118 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 94987426 Common xanB phosphomannose isomerase/GDP-mannose pyrophosphorylase LI0984 165 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 94987274 Common potD Spermidine/putrescine-binding periplasmic protein LI0832 135 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 94987231 Common queA S-adenosylmethionine:tRNA-ribosyltransferase- isomerase (queuine synthetase) LI0789 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 94986716 Pathogen - NA LI0272 1 None None None 94986752 Common - 2-methylthioadenine synthetase LI0308 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 94987391 Pathogen - NA LI0949 1 None None None 94986937 Common - hypothetical protein LI0494 2 None None None 94986801 Common pcm Protein-L-isoaspartate carboxylmethyltransferase LI0357 62 COG2519 GCD14, tRNA(1-methyladenosine) methyltransferase and related methyltransferases Translation, ribosomal structure and biogenesis 94986665 Common rplS 50S ribosomal protein L19 LI0221 215 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 94987036 Common rnb Exoribonuclease R LI0594 192 COG0557 VacB, Exoribonuclease R Transcription 94987317 Common - Methylenetetrahydrofolate dehydrogenase (NADP+) / Methenyltetrahydrofolate cyclohydrolase LI0875 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 94987238 Common lon predicted ATP-dependent protease LI0796 212 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 94987137 Common tolQ Biopolymer transport proteins LI0695 143 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 94987293 Common - NAD(P)H-dependent flavin reductase LI0851 53 COG0778 NfnB, Nitroreductase Energy production and conversion 94987054 Common - FOG: TPR repeat LI0612 142 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 94987586 Common cheA_2 Chemotaxis protein histidine kinase and related kinases LI1144 153 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 94987454 Common lon predicted ATP-dependent protease LI1012 91 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 94987528 Common glpA Anaerobic glycerol-3-phosphate dehydrogenase subunit A LI1086 162 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 94986455 Pathogen - NA LI0010 1 None None None 94986893 Common purL phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain LI0450 232 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 94987321 Common pgi Glucose-6-phosphate isomerase LI0879 197 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 94987253 Common pit Phosphate/sulphate permeases LI0811 167 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 94986541 Common - hypothetical protein LI0096 3 None None None 94987098 Common argG Argininosuccinate synthase LI0656 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 94987328 Common - Glutamyl-tRNA (Gln) amidotransferase subunit C LI0886 14 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 94986629 Common - MoxR-like ATPases LI0185 90 COG0714 COG0714, MoxR-like ATPases General function prediction only 94987523 Common oppD oligopeptide ABC transporter LI1081 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 94986511 Common ftsK DNA segregation ATPase FtsK/SpoIIIE and related proteins LI0066 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 94987428 Common hisS histidyl-tRNA synthetase LI0986 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 94986877 Common - Glycosyltransferase LI0434 101 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 94986507 Common ybeN Nicotinic acid mononucleotide adenylyltransferase LI0062 147 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 94987539 Common - predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis LI1097 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 94987469 Common lysU Lysyl-tRNA synthetase (class II) LI1027 247 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 94987363 Common purD phosphoribosylamine-glycine ligase LI0921 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 94986833 Common - Modification methylase BepI (Cytosine-specific methyltransferase BepI) LI0389 117 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 94987354 Common dnaK Molecular chaperone dnaK LI0912 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 94986634 Common - hypothetical protein LI0190 67 COG1624 COG1624, Uncharacterized conserved protein Function unknown 94986919 Common nrdA ribonucleotide-diphosphate reductase subunit alpha LI0476 227 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 94987303 Common cbiO ABC-type cobalt transport system, ATPase component LI0861 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 94987288 Common - Lipopolysaccharide core biosynthesis protein RfaG (Glucosyltransferase I) LI0846 86 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 94986996 Common - NA LI0554 4 None None None 94987504 Common truA tRNA pseudouridine synthase A LI1062 234 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 94986477 Pathogen - NA LI0032 1 None None None 94987352 Common cmk Cytidylate kinase LI0910 205 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 94986498 Pathogen - NA LI0053 1 None None None 94986927 Common - hypothetical protein LI0484 2 None None None 94986691 Common - hypothetical protein LI0247 7 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 94986616 Common - hypothetical protein LI0172 3 None None None 94986468 Common ogt O-6-alkylguanine-DNA/cysteine-protein methyltransferase LI0023 154 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 94987592 Common - putative regulator LI1150 128 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 94987248 Common menE O-succinylbenzoic acid--CoA ligase LI0806 179 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 94986906 Common - hypothetical protein LI0463 9 COG5459 COG5459, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 94987281 Common xthA Exonuclease III LI0839 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 94986750 Common - predicted integral membrane protein LI0306 53 COG0392 COG0392, Predicted integral membrane protein Function unknown 94987219 Common - Phosphatidylserine synthase LI0777 151 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 94986481 Common rfaF ADP-heptose:LPS heptosyltransferase II LI0036 77 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 94986614 Common relA Guanosine polyphosphate pyrophosphohydrolases/synthetases LI0170 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 94987236 Common clpP Protease subunit of ATP-dependent Clp proteases LI0794 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 94986740 Common purM phosphoribosylaminoimidazole synthetase LI0296 232 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 94986517 Pathogen - NA LI0072 1 None None None 94987123 Common kdtA 3-deoxy-D-manno-octulosonic-acid transferase LI0681 126 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 94987544 Common murD UDP-N-acetylmuramoylalanine-D-glutamate ligase LI1102 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 94986849 Common xseA Exonuclease VII, large subunit LI0405 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 94987127 Common dnaJ DnaJ-class molecular chaperone with C-terminal Zn finger domain LI0685 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 94987511 Common rnpA RNase P protein component LI1069 19 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 94987437 Common oprM outer membrane efflux protein LI0995 136 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 94986486 Pathogen - NA LI0041 1 None None None 94987067 Common groEL chaperonin GroEL LI0625 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 94987472 Common pstA phosphate ABC transporter, permease protein LI1030 210 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 94987141 Common - hypothetical protein LI0699 2 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 94986922 Common - alginate O-acetylation protein LI0479 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 94987385 Common rpsG 30S ribosomal protein S7 LI0943 240 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 94987294 Common - NAD(P)H nitroreductase LI0852 24 COG0778 NfnB, Nitroreductase Energy production and conversion 94986732 Common - PAP2 superfamily protein LI0288 21 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 94987606 Common YscL putative type III secretion protein LI1164 16 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 94987518 Common glk Glucokinase LI1076 80 COG0837 Glk, Glucokinase Carbohydrate transport and metabolism 94986657 Common infC translation initiation factor IF-3 LI0213 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 94987415 Common rplF 50S ribosomal protein L6 LI0973 232 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 94986967 Pathogen - NA LI0524 1 None None None 94987090 Common valS valyl-tRNA synthetase LI0648 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 94986685 Common uvrB excinuclease ABC subunit B LI0241 233 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 94987028 Common - hypothetical protein LI0586 54 COG4717 COG4717, Uncharacterized conserved protein Function unknown 94986761 Common - Adenylate kinase and related kinases LI0317 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 94987565 Common prc Periplasmic protease LI1123 183 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 94987083 Common fliN Flagellar motor switch/type III secretory pathway protein LI0641 124 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 94987445 Common lysC Aspartokinases LI1003 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 94987163 Common - transporter, putative LI0721 15 COG0679 COG0679, Predicted permeases General function prediction only 94986971 Common flhF Flagellar GTP-binding protein LI0529 65 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 94986583 Pathogen - NA LI0138 1 None None None 94987484 Pathogen - NA LI1042 1 None None None 94986535 Common - pantothenate kinase LI0090 115 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 94986604 Common fabF/fabB 3-oxoacyl-(acyl-carrier-protein) synthase LI0160 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 94987183 Common flgG flagellar basal body rod protein FlgG LI0741 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 94986897 Common - hypothetical protein LI0454 2 None None None 94986978 Common mgpa Exopolyphosphatase-related proteins LI0536 74 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 94987449 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B LI1007 214 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 94987557 Common flbD Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains LI1115 171 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 94986571 Common clpB ATPases with chaperone activity, ATP-binding subunit LI0126 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 162138293 Common metK S-adenosylmethionine synthetase LI0726 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 94986981 Common - hypothetical protein LI0539 5 None None None 94986796 Common rpsF 30S ribosomal protein S6 LI0352 5 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 94987084 Common fliL Flagellar basal body-associated protein LI0642 38 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 94986840 Common rodA rod shape-determining protein RodA LI0396 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 94987073 Common hypE Hydrogenase maturation factor LI0631 122 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 94986911 Common rfbB dTDP-D-glucose 4,6-dehydratase LI0468 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 94987478 Pathogen - NA LI1036 1 None None None 94986458 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase LI0013 146 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 94986956 Common - glycosyltransferase LI0513 166 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 94987334 Common lnt apolipoprotein N-acyltransferase LI0892 163 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 94987401 Common rpsJ 30S ribosomal protein S10 LI0959 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 94987525 Common feoB Fe2+ transport system protein B LI1083 162 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 94987453 Common hemC Porphobilinogen deaminase LI1011 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 94987042 Common - predicted membrane protein LI0600 7 COG3924 COG3924, Predicted membrane protein Function unknown 94986728 Common - predicted exonuclease of the beta-lactamase fold involved in RNA processing LI0284 124 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 94986987 Common - NA LI0545 2 None None None 94987025 Common - hypothetical protein LI0583 4 None None None 94987574 Common tpiA Triosephosphate isomerase LI1132 227 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 94987365 Common lepB Signal peptidase I LI0923 209 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 94987297 Common - Flagellar biosynthesis/type III secretory pathway protein LI0855 11 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 94986676 Common - ABC-type transport system involved in resistance to organic solvents, ATPase component LI0232 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 94986627 Common - hypothetical protein GSU2154 LI0183 4 None None None 94986865 Common bioF 7-keto-8-aminopelargonate synthetase and related enzymes LI0421 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 94987059 Common yljA hypothetical protein LI0617 121 COG2127 COG2127, Uncharacterized conserved protein Function unknown 94987224 Common thiD Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase LI0782 216 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 94986620 Pathogen - NA LI0176 1 None None None 94987151 Common ribF FAD synthase LI0709 211 COG0196 RibF, FAD synthase Coenzyme metabolism 94986820 Common - membrane proteins related to metalloendopeptidases LI0376 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 94987170 Common lytB ribosomal protein S1 LI0728 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 94986826 Common pyrH Uridylate kinase LI0382 243 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 94987279 Common - hypothetical protein LI0837 2 None None None 94987245 Common - hypothetical protein LI0803 3 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 94987258 Common - ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase LI0816 130 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 94986932 Common - Acetyl-CoA carboxylase alpha subunit LI0489 177 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 94986755 Common pyrF Orotidine-5'-phosphate decarboxylase LI0311 170 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 94986534 Common folE 7-cyano-7-deazaguanine reductase LI0089 104 COG0780 COG0780, Enzyme related to GTP cyclohydrolase I General function prediction only 94986804 Common nadC Nicotinate-nucleotide pyrophosphorylase LI0360 203 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 94987139 Common rubA Rubredoxin 2 (Rd-2) LI0697 107 COG1773 COG1773, Rubredoxin Energy production and conversion 94986845 Common atpD F0F1 ATP synthase subunit alpha LI0401 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 94987001 Common rplM 50S ribosomal protein L13 LI0559 227 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 94987158 Common gln ABC-type amino acid transport/signal transduction systems, periplasmic component/domain LI0716 172 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 94987100 Common trmU predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain LI0658 27 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 94986466 Common - Zn-dependent proteases LI0021 96 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 94986641 Common - similar to endo-1,4-beta-xylanase LI0197 14 None None None 94986590 Common typA/bipA GTP-binding protein lepA LI0145 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 94987180 Common - peptidyl-tRNA hydrolase LI0738 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 94987403 Common rplD 50S ribosomal protein L4 LI0961 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 94986453 Pathogen - NA LI0008 1 None None None 94987609 Common - anti-anti-sigma factor LI1167 53 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 94987199 Common menA hypothetical protein LI0757 95 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 94986789 Common - SAM-dependent methyltransferases LI0345 43 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 94987439 Common purB Adenylosuccinate lyase LI0997 238 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 94987144 Common maf nucleotide-binding protein implicated in inhibition of septum formation LI0702 191 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 94987613 Common - 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases LI1171 142 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 94987204 Common surE predicted acid phosphatase LI0762 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 94987546 Common murG UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase LI1104 210 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 94986544 Common argC Acetylglutamate semialdehyde dehydrogenase LI0099 213 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 94987502 Common - Flagellar biosynthesis chaperone LI1060 9 None None None 94987497 Common lpxB Lipid A disaccharide synthetase LI1055 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 94986650 Common - predicted Fe-S oxidoreductases LI0206 178 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 94987006 Common pgpA Phosphatidylglycerophosphatase A and related proteins LI0564 104 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 94986701 Common dnaE DNA polymerase III, alpha subunit LI0257 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 94987347 Common rpoB DNA-directed RNA polymerase subunit beta LI0905 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 94986948 Common thiH Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes LI0505 53 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 94986729 Common - cell wall-associated hydrolases (invasion-associated proteins) LI0285 23 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 94986889 Common - 4-diphosphocytidyl-2-methyl-D-erithritol synthase LI0446 196 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 94986525 Common - NA LI0080 2 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 94987076 Common - hypothetical protein LI0634 2 None None None 94986509 Common - predicted transcriptional regulator LI0064 34 COG4957 COG4957, Predicted transcriptional regulator Transcription 94987089 Common - hypothetical protein LI0647 73 COG0391 COG0391, Uncharacterized conserved protein Function unknown 94986784 Common - hypothetical protein LI0340 2 COG2881 COG2881, Uncharacterized protein conserved in archaea Function unknown 94986693 Common recN ATPase involved in DNA repair LI0249 206 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 94987255 Common rluD Pseudouridylate synthases, 23S RNA-specific LI0813 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 94986859 Common - probable kynureninase (kyurenine hydrolase) LI0415 104 COG3844 COG3844, Kynureninase Amino acid transport and metabolism 94986883 Common hyaB hydrogenase-1 large subunit LI0440 100 COG0374 HyaB, Ni,Fe-hydrogenase I large subunit Energy production and conversion 94987308 Common - predicted membrane metal-binding protein LI0866 124 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 94986880 Common - probable histidine acid phosphatase LI0437 16 None None None 94986567 Common - Cytochrome c biogenesis protein LI0122 5 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 94987413 Common rplE 50S ribosomal protein L5 LI0971 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 94986739 Pathogen - NA LI0295 1 None None None 94986483 Common - putative exported nuclease LI0038 63 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 94987395 Common ccmC ABC-type transport system involved in cytochrome c biogenesis, permease component LI0953 174 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 94987154 Common pyrD Dihydroorotate dehydrogenase LI0712 191 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 94987594 Common - NA LI1152 2 None None None 94987142 Common - FOG: TPR repeat LI0700 6 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 94986936 Common glnS glutaminyl-tRNA synthetase LI0493 243 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 94987581 Common cheR Methylase of chemotaxis methyl-accepting proteins LI1139 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 94986488 Pathogen - NA LI0043 1 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 94987350 Common hypD Hydrogenase maturation factor LI0908 109 COG0409 HypD, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 94986904 Common - hypothetical protein LI0461 3 None None None 94987476 Pathogen - NA LI1034 1 None None None 94986687 Common dapB Dihydrodipicolinate reductase LI0243 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 94987129 Common - Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains LI0687 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 94987200 Common - hypothetical protein LI0758 17 None None None 94986612 Common - Superfamily II DNA/RNA helicases, SNF2 family LI0168 134 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 94986446 Common dnaA ATPase involved in DNA replication initiation LI0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 94987179 Common - 50S ribosomal protein L25/general stress protein Ctc LI0737 165 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 94987234 Common porB ferredoxin oxidoreductases, gamma subunit LI0792 72 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 94986920 Common nrdB Ribonucleotide reductase, beta subunit LI0477 133 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 94987210 Common nifr3 tRNA-dihydrouridine synthase LI0768 207 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 94986737 Common fumB fumarate hydratase LI0293 146 COG1838 FumA, Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain Energy production and conversion 94987378 Common pqqL predicted Zn-dependent peptidases LI0936 201 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 94986491 Common - hypothetical protein VPA1572 LI0046 20 COG4748 COG4748, Uncharacterized conserved protein Function unknown 94987333 Common - hypothetical protein LI0891 163 COG1576 COG1576, Uncharacterized conserved protein Function unknown 94986873 Common - 141aa long hypothetical histidine triad nucleotide-binding protein LI0430 227 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 94987430 Common dppF oligopeptide ABC transporter (ATP-binding protein) LI0988 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 94987563 Common ndk nucleoside-diphosphate kinase LI1121 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 94986875 Common - predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division LI0432 143 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 94986703 Common - NA LI0259 3 COG2331 COG2331, Uncharacterized protein conserved in bacteria Function unknown 94987555 Common argF Ornithine carbamoyltransferase LI1113 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 94986523 Common ugpA inner membrane component of binding-protein-dependent transport system LI0078 150 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 94986901 Common - Ribosome-associated protein Y (PSrp-1) LI0458 117 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 94987542 Common murF UDP-N-acetylmuramyl pentapeptide synthase LI1100 209 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 94987622 Common bioY hypothetical protein LI1180 113 COG1268 BioY, Uncharacterized conserved protein General function prediction only 94987061 Common aat leucyl/phenylalanyl-tRNA--protein transferase LI0619 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 94986645 Common - hypothetical protein LI0201 3 None None None 94987466 Common - Outer membrane protein/protective antigen OMA87 LI1024 162 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 94987417 Common rpsE 30S ribosomal protein S5 LI0975 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 94987373 Common rplJ 50S ribosomal protein L10 LI0931 209 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 94987367 Common qacE membrane transporters of cations and cationic drugs LI0925 132 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 94986913 Common - membrane proteins related to metalloendopeptidases LI0470 188 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 94987408 Common rpsC 30S ribosomal protein S3 LI0966 248 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 94987338 Common dapA Dihydrodipicolinate synthase/N-acetylneuraminate lyase LI0896 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 94986787 Common codA Cytosine/adenosine deaminases LI0343 210 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 94987387 Common - predicted dienelactone hydrolase LI0945 26 COG4188 COG4188, Predicted dienelactone hydrolase General function prediction only 94987443 Common napC cytochrome c nitrite reductase small subunit LI1001 40 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 94986573 Common glnP ABC-type amino acid transport system, permease component LI0128 179 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 94987075 Common flgM hypothetical protein LI0633 5 COG2747 FlgM, Negative regulator of flagellin synthesis (anti-sigma28 factor) Transcription / Cell motility and secretion / Intracellular trafficking and secretion 94987133 Common pal Outer membrane protein and related peptidoglycan-associated (lipo)proteins LI0691 148 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 94986969 Common cheY CheY-like receiver LI0526 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 94987516 Common - RecB family exonuclease LI1074 25 COG2887 COG2887, RecB family exonuclease DNA replication, recombination, and repair 94987104 Common - hypothetical protein LI0662 16 COG5563 COG5563, Predicted integral membrane proteins containing uncharacterized repeats Function unknown 94987081 Common fliP flagellar biosynthesis protein FliP LI0639 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 94986619 Pathogen - hyphotheical protein LI0175 1 None None None 94986475 Pathogen - NA LI0030 1 None None None 94987125 Common - hypothetical protein LI0683 4 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 94986925 Common motA flagellar motor protein MotA LI0482 106 COG1291 MotA, Flagellar motor component Cell motility and secretion 94986945 Common pabC predicted periplasmic solute-binding protein LI0502 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 94986763 Common - ADP-heptose:LPS heptosyltransferase LI0319 45 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 94986623 Common tetW ribosomal protection tetracycline resistance protein LI0179 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 94986591 Common - translation-associated GTPase LI0146 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 94986602 Common ribD Pyrimidine reductase, riboflavin biosynthesis LI0157 225 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 94987034 Common maa maltose transacetylase LI0592 177 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 94987045 Common - two-component response regulator LI0603 43 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 94986600 Common ribA GTP cyclohydrolase II LI0155 232 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 94986674 Common - hypothetical protein LI0230 2 COG3087 FtsN, Cell division protein Cell division and chromosome partitioning 94987212 Common - 5-formyltetrahydrofolate cyclo-ligase LI0770 146 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 94986863 Common - short chain dehydrogenase, putative LI0419 221 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 94987611 Common - putative transglycosylase LI1169 183 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 94987165 Common mltA membrane-bound lytic murein transglycosylase LI0723 93 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 94986506 Pathogen - NA LI0061 1 None None None 94986470 Common ppsA phosphoenolpyruvate synthase/pyruvate phosphate dikinase LI0025 232 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 94986776 Common glgP carbohydrate phosphorylase family protein LI0332 143 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 94986539 Common pfk Fructose-2,6-bisphosphatase LI0094 112 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 94987050 Common cysS Cysteinyl-tRNA synthetase LI0608 242 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 94987277 Common - hypothetical protein LI0835 18 None None None 94986653 Common - hypothetical protein LI0209 9 None None None 94987527 Common - anaerobic glycerol-3-phosphate dehydrogenase subunit B LI1085 32 COG3075 GlpB, Anaerobic glycerol-3-phosphate dehydrogenase Amino acid transport and metabolism 94986753 Common yicC hypothetical protein LI0309 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 94987325 Common - predicted Zn-dependent hydrolases of the beta-lactamase fold LI0883 123 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 94986569 Common cbpA DnaJ-class molecular chaperone LI0124 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 94986954 Common - hypothetical protein LI0511 93 COG2947 COG2947, Uncharacterized conserved protein Function unknown 94987455 Common nar Permeases of the major facilitator superfamily LI1013 9 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 94986994 Common - Signal transduction histidine kinase LI0552 132 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 94987270 Common gpsA Glycerol-3-phosphate dehydrogenase LI0828 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 94986934 Common - hypothetical protein LI0491 2 None None None 94987470 Common - Phosphate-binding protein LI1028 138 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 94987627 Common - NA LI1185 3 COG3038 CybB, Cytochrome B561 Energy production and conversion 94987017 Common - Signal renition particle GTPase LI0575 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 94986581 Common - hypothetical protein LI0136 48 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 94987313 Common htrB acyltransferase, HtrB/MsbB family LI0871 79 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 94986625 Common - endonuclease I LI0181 34 COG2356 EndA, Endonuclease I DNA replication, recombination, and repair 94986546 Common dgkA diacylglycerol kinase LI0101 70 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 94987345 Common - hypothetical protein LI0903 2 None None None 94987264 Common - Histidinol phosphatase and related hydrolases of the PHP family LI0822 21 None None None 94987576 Common - NTP pyrophosphohydrolases including oxidative damage repair enzymes LI1134 4 COG1443 Idi, Isopentenyldiphosphate isomerase Lipid metabolism 94987343 Common dsr Sulfite reductase, dissimilatory-type gamma subunit LI0901 59 COG2920 DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit Inorganic ion transport and metabolism 94987318 Common - tRNA and rRNA cytosine-C5-methylases LI0876 207 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 94987189 Common flgK Flagellar hook-associated protein LI0747 124 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 94987421 Common rpsM 30S ribosomal protein S13 LI0979 235 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 94987078 Common - hypothetical protein LI0636 80 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 94987027 Common - DNA repair exonuclease LI0585 65 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 94986496 Common uvrD ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) LI0051 211 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 94986695 Common oppB ABC-type dipeptide/oligopeptide/nickel transport systems, permease components LI0251 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 94987202 Common tmk Thymidylate kinase LI0760 224 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 94986806 Common nadB Aspartate oxidase LI0362 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 94987495 Common - hypothetical protein LI1053 86 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 94987107 Pathogen - NA LI0665 1 None None None 94987118 Common hflC membrane protease subunits, stomatin/prohibitin homologs LI0676 210 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 94987261 Common pyrC Dihydroorotase and related cyclic amidohydrolases LI0819 212 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 94986607 Common plsX fatty acid/phospholipid synthesis protein LI0163 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 94987530 Common - NA LI1088 2 None None None 94986782 Common livH branched chain amino acid ABC transporter, permease protein LI0338 151 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 94986730 Common - cell wall-associated hydrolases (invasion-associated proteins) LI0286 23 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 94986647 Common trmU predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain LI0203 214 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 94986575 Common hisJ Histidinol phosphatase and related phosphatases LI0130 130 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 94987486 Common - hypothetical protein LI1044 11 COG3009 COG3009, Uncharacterized protein conserved in bacteria Function unknown 94986885 Common hyaD processing of HyaA and HyaB proteins LI0442 85 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 94986766 Common hemA glutamyl-tRNA reductase LI0322 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 94987048 Common - transcriptional regulator LI0606 116 COG1802 GntR, Transcriptional regulators Transcription 94986812 Common ygjD Metal-dependent proteases with possible chaperone activity LI0368 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 94987620 Common - ABC-type cobalt transport system, permease component CbiQ and related transporters LI1178 3 None None None 94987114 Common pcrA Superfamily I DNA and RNA helicases LI0672 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 94987197 Common rpsA 30S ribosomal protein S1 LI0755 233 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 94987243 Common glmU N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) LI0801 231 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 94987292 Common - hypothetical protein LI0850 136 COG2081 COG2081, Predicted flavoproteins General function prediction only 94987194 Common - Sulfate transporter family protein LI0752 161 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 94987156 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein LI0714 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 94987380 Common purF Glutamine phosphoribosylpyrophosphate amidotransferase LI0938 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 94987432 Common carA carbamoyl phosphate synthase small subunit LI0990 232 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 94987173 Common acpS holo-[acyl-carrier protein] synthase LI0731 69 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 94986852 Common dsx 1-deoxy-D-xylulose-5-phosphate synthase LI0408 225 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 94986464 Common tagD glycerol-3-phosphate cytidyltransferase LI0019 135 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 94987603 Common - NA LI1161 3 None None None 94987301 Common flgC Flagellar basal body rod protein LI0859 126 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 94987209 Common def N-formylmethionyl-tRNA deformylase LI0767 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 94987254 Common - NA LI0812 4 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 94987582 Common soj ATPases involved in chromosome partitioning LI1140 203 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 94987016 Common - predicted RNA-binding protein (contains KH domain) LI0574 57 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 94987004 Pathogen - NA LI0562 1 COG5278 COG5278, Predicted periplasmic ligand-binding sensor domain Signal transduction mechanisms 94987046 Common - PleD LI0604 176 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 94987148 Common - hypothetical protein LI0706 236 COG1379 COG1379, Uncharacterized conserved protein Function unknown 94987617 Common - NA LI1175 2 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 94986512 Common - translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) LI0067 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 94986993 Common yscU translocation protein in type III secretion LI0551 129 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 94986680 Common mutS DNA mismatch repair protein LI0236 204 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 94986593 Common lon predicted ATP-dependent protease LI0148 205 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 94987561 Common gapB Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase LI1119 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 94987316 Common - Fthfsdc1 protein LI0874 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 94987222 Common fruK Sugar kinases, ribokinase family LI0780 108 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 94986630 Common - hypothetical protein LI0186 15 None None None 94986463 Common gltP proton/sodium-glutamate symport protein LI0018 164 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 94986785 Common - hypothetical protein LI0341 2 None None None 94986564 Common msrA peptide methionine sulfoxide reductase LI0119 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 94987241 Common - hypothetical protein LI0799 135 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 94986745 Common recO hypothetical protein LI0301 26 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 94987406 Common rpsS 30S ribosomal protein S19 LI0964 248 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 94986502 Common - nitrate ABC transporter, ATP-binding protein (nrtC-1) LI0057 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 94987489 Common ttg2B ABC-type transport system involved in resistance to organic solvents, permease component LI1047 146 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 94987053 Common - hypothetical protein LI0611 2 None None None 94986579 Common - predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain LI0134 30 COG1315 COG1315, Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain DNA replication, recombination, and repair 94986953 Common terC membrane protein TerC, possibly involved in tellurium resistance LI0510 100 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 94986664 Common trmD tRNA-(guanine-N1)-methyltransferase LI0220 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 94986943 Common livF branched chain amino acid ABC transporter, ATP-binding protein LI0500 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 94986791 Common flgE Flagellar hook protein FlgE LI0347 201 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 94986608 Common - predicted metal-binding, possibly nucleic acid-binding protein LI0164 37 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 94987184 Common - hypothetical protein LI0742 22 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 94986780 Common livG branched chain amino acid ABC transporter, ATP-binding protein LI0336 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 94987371 Common - Glycosyltransferases involved in cell wall biogenesis LI0929 183 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 94987102 Common bfr Bacterioferritin (cytochrome b1) LI0660 96 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 94987423 Common rpsD 30S ribosomal protein S4 LI0981 234 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 94986522 Common ugpB probable extracellular solute-binding protein LI0077 112 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 94987117 Common hflK membrane protease subunits, stomatin/prohibitin homologs LI0675 193 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 94986735 Common - hypothetical protein LI0291 33 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 94986725 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase LI0281 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 94987190 Common flgL Flagellin and related hook-associated proteins LI0748 86 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 94986898 Common - hypothetical protein LI0455 6 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 94987520 Common HydH Signal transduction histidine kinase LI1078 223 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 94986854 Common trpA bifunctional tryptophan synthase TRPB LI0410 218 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 94987529 Common - hypothetical protein LI1087 36 COG2431 COG2431, Predicted membrane protein Function unknown 94987433 Common - GluNAc transferase LI0991 49 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 94987451 Common yfjB predicted sugar kinase LI1009 237 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 94987624 Common recA recombinase A LI1182 215 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 94987131 Common grsT hypothetical protein LI0689 84 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 94987030 Common tatC Sec-independent protein secretion pathway component TatC LI0588 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 94986751 Common greA transcription elongation factor greA LI0307 204 COG0782 GreA, Transcription elongation factor Transcription 94987263 Common miaB 2-methylthioadenine synthetase LI0821 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 94986715 Common - hypothetical protein LI0271 4 None None None 94987097 Common gloB Zn-dependent hydrolases, including glyoxylases LI0655 220 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 94987397 Common ccmA/ccmB ABC-type multidrug transport system, ATPase component LI0955 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 94986869 Common bioA Adenosylmethionine-8-amino-7-oxononanoate aminotransferase LI0426 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 94986503 Common - thiamine biosynthesis protein, putative LI0058 24 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 94987320 Common atoS Signal transduction histidine kinase LI0878 223 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 94986652 Common - hypothetical protein LI0208 13 None None None 94986668 Common - predicted methyltransferases LI0224 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 94987136 Common exbD Biopolymer transport protein LI0694 135 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 94987515 Common rncS Ribonuclease D LI1073 27 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 94986985 Common nolT LscJ LI0543 33 COG4669 EscJ, Type III secretory pathway, lipoprotein EscJ Intracellular trafficking and secretion 94987037 Common lpxK Tetraacyldisaccharide-1-P 4'-kinase LI0595 130 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 94987232 Common vorB 2-ketoisovalerate ferredoxin reductase LI0790 113 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 94986456 Common polB DNA polymerase I-3'-5' exonuclease and polymerase domains LI0011 171 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 94987273 Common potC spermidine/putrescine ABC transporter membrane protein LI0831 180 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 94986860 Common - probable permease of ABC transporter LI0416 101 COG4120 COG4120, ABC-type uncharacterized transport system, permease component General function prediction only 94986673 Common argS Arginyl-tRNA synthetase LI0229 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 94986938 Common - Glycosyltransferase LI0495 57 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 94986609 Common mutY A/G-specific DNA glycosylase LI0165 231 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 94986473 Common - NA LI0028 2 None None None 94987229 Common dnaA ATPase involved in DNA replication initiation LI0787 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 94986835 Common - predicted Fe-S oxidoreductase LI0391 81 COG1242 COG1242, Predicted Fe-S oxidoreductase General function prediction only 94987244 Common - predicted HD superfamily hydrolase LI0802 76 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 94987135 Common - membrane protein involved in colicin uptake LI0693 3 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 94986596 Common - hypothetical protein LI0151 2 None None None 94987388 Common gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA LI0946 193 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 94987251 Common - NA LI0809 2 None None None 94986646 Common purA Adenylosuccinate synthase LI0202 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 94986449 Common hly hemolysin A LI0004 130 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 94986830 Common dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase LI0386 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 94987175 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain LI0733 171 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 94987579 Common cheB Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain LI1137 214 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 94986810 Common trxB Thioredoxin reductase LI0366 249 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 94986961 Common dnaG DNA primase (bacterial type) LI0518 216 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 94986621 Common - hypothetical protein LI0177 4 None None None 94986976 Common nusA transcription elongation factor NusA LI0534 216 COG0195 NusA, Transcription elongation factor Transcription 94986697 Common - hypothetical protein LI0253 10 None None None 94987442 Common - hypothetical protein LI1000 2 None None None 94986964 Common ksgA dimethyladenosine transferase LI0521 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 94987479 Pathogen - NA LI1037 1 None None None 94986540 Common - CheY-like receiver LI0095 2 None None None 94987187 Common flgJ membrane proteins related to metalloendopeptidases LI0745 34 COG3951 COG3951, Rod binding protein Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 94987418 Common rplO 50S ribosomal protein L15 LI0976 217 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 94986705 Common gad glutamate decarboxylase isozyme LI0261 69 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 94987152 Common fliC Flagellin and related hook-associated proteins LI0710 119 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 94987541 Common murE UDP-N-acetylmuramyl tripeptide synthase LI1099 212 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 94987167 Common hisB Histidinol phosphatase and related hydrolases of the PHP family LI0725 36 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 94986916 Common - putative DNA methylase protein LI0473 52 COG1002 COG1002, Type II restriction enzyme, methylase subunits Defense mechanisms 94987227 Common gyrB Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit LI0785 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 94987487 Common pqiB Paraquat-inducible protein B LI1045 61 COG3008 PqiB, Paraquat-inducible protein B General function prediction only 94987390 Common - Glycosyltransferase LI0948 204 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 94986529 Common - NA LI0084 2 None None None 94986949 Common thiF thiamine biosynthesis protein ThiF LI0506 197 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 94986495 Common - uncharacterized protein involved in outer membrane biogenesis LI0050 9 None None None 94986562 Common cysG Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) LI0117 207 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 94986942 Common livG branched chain amino acid ABC transporter, ATP-binding protein LI0499 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 94987506 Common fdhF Fe-S-cluster-containing hydrogenase components 1 LI1064 160 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 94986577 Common selA selenocysteine synthase LI0132 74 COG1921 SelA, Selenocysteine synthase [seryl-tRNASer selenium transferase] Amino acid transport and metabolism 94986659 Common pheS Phenylalanyl-tRNA synthetase alpha subunit LI0215 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 94987289 Common - hypothetical protein LI0847 9 COG5266 CbiK, ABC-type Co2+ transport system, periplasmic component Inorganic ion transport and metabolism 94986478 Common ostA Organic solvent tolerance protein OstA LI0033 112 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 94987568 Common - RNA methyltransferase, TrmH family, group 2, putative LI1126 160 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 94987326 Common selB Selenocysteine-specific translation elongation factor LI0884 249 COG3276 SelB, Selenocysteine-specific translation elongation factor Translation, ribosomal structure and biogenesis 94987493 Common ileS isoleucyl-tRNA synthetase LI1051 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 94986555 Common smf predicted Rossmann fold nucleotide-binding protein involved in DNA uptake LI0110 211 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 94986793 Common purC phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase LI0349 165 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 94987356 Common dacC D-alanyl-D-alanine carboxypeptidase LI0914 13 COG1876 VanY, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 94986551 Common ilv acetolactate synthase LI0106 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 94987286 Common - tRNA and rRNA cytosine-C5-methylases LI0844 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 94986951 Common - Multidrug resistance protein norM LI0508 166 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 94986531 Common - Putative beta-D-galactosidase LI0086 6 COG2731 EbgC, Beta-galactosidase, beta subunit Carbohydrate transport and metabolism 94987553 Common - predicted amidophosphoribosyltransferases LI1111 172 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 94986819 Common pcm Protein-L-isoaspartate carboxylmethyltransferase LI0375 155 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 94987537 Common pykF Pyruvate kinase LI1095 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 94987337 Common dapF diaminopimelate epimerase LI0895 203 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 94987062 Common clr3 Deacetylases, including yeast histone deacetylase and acetoin utilization protein LI0620 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 94986870 Common - hypothetical protein LI0427 45 COG3786 COG3786, Uncharacterized protein conserved in bacteria Function unknown 94986484 Pathogen - NA LI0039 1 None None None 94986722 Common porA Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit LI0278 120 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 94987092 Common - predicted Zn-dependent peptidases, insulinase-like LI0650 51 COG1026 COG1026, Predicted Zn-dependent peptidases, insulinase-like General function prediction only 94987501 Common - redox-sensing transcriptional repressor Rex LI1059 56 COG2344 COG2344, AT-rich DNA-binding protein General function prediction only 94986909 Common galE nucleoside-diphosphate-sugar epimerases LI0466 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 94986682 Common cca polyA polymerase family protein LI0238 160 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 94987307 Common mviN uncharacterized membrane protein, putative virulence factor LI0865 189 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 94987214 Common - hypothetical protein LI0772 67 COG1636 COG1636, Uncharacterized protein conserved in bacteria Function unknown 94987369 Common mviN uncharacterized membrane protein, putative virulence factor LI0927 176 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 94987473 Common pstB Phosphate ABC transporter, ATP-binding protein LI1031 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 94987056 Common - Thiol-disulfide isomerase and thioredoxins LI0614 109 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 94987013 Common rnc dsRNA-specific ribonuclease LI0571 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 94987558 Common priS hydroxylamine reductase LI1116 75 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 94987071 Common - hypothetical protein LI0629 19 None None None 94987331 Common - hypothetical protein LI0889 237 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 94987595 Common - putative outer protein N LI1153 8 None None None 94986636 Common - phosphomannomutase LI0192 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 94987596 Common - NA LI1154 2 None None None 94986747 Common ppi Parvulin-like peptidyl-prolyl isomerase LI0303 50 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 94987482 Pathogen - NA LI1040 1 None None None 94987268 Common rpmB 50S ribosomal protein L28 LI0826 57 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 94986837 Common mreC cell shape-determining protein LI0393 139 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 94986500 Common mltD membrane-bound lytic murein transglycosylase D (MltD) LI0055 143 COG3858 COG3858, Predicted glycosyl hydrolase General function prediction only 94986881 Common - PhyA2 LI0438 16 None None None 94986718 Common - uncharacterized flavoproteins LI0274 83 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 94986520 Common icc phosphodiesterase LI0075 88 COG1409 Icc, Predicted phosphohydrolases General function prediction only 94986778 Common hslU ATP-dependent protease ATP-binding subunit LI0334 209 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 94987150 Common - Protein-disulfide isomerase LI0708 105 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 94986856 Common trpF phosphoribosyl anthranilate isomerase LI0412 197 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 94987182 Common flgF Flagellar basal body rod protein LI0740 125 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 94986886 Common - hypothetical protein LI0443 2 None None None 94986537 Common rfaF/rfaQ ADP-heptose:LPS heptosyltransferase LI0092 93 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 94987629 Common ruvB Holliday junction DNA helicase B LI1187 222 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 94986572 Common glnQ ABC-type polar amino acid transport system, ATPase component LI0127 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 94987377 Common tufA elongation factor Tu LI0935 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 94986850 Common - membrane proteins related to metalloendopeptidases LI0406 192 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 94987435 Common acrA probable multidrug efflux membrane permease LI0993 155 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 94987207 Common - hypothetical protein LI0765 29 COG1852 COG1852, Uncharacterized conserved protein Function unknown 94987610 Common rsbW sigma regulatory factor-histidine kinase LI1168 31 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 94987265 Common pepQ Xaa-Pro aminopeptidase LI0823 248 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 94987584 Common cheY CheY-like receiver LI1142 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 94987630 Common thyX FAD-dependent thymidylate synthase LI1188 66 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 94987009 Common - Flagellar hook capping protein LI0567 125 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 94986867 Common bioC Ubie_methyltran, ubiE/COQ5 methyltransferase family LI0424 75 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 94987608 Common - putative translocation protein in type III secretion LI1166 6 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 94986929 Common motA Flagellar motor component LI0486 103 COG1291 MotA, Flagellar motor component Cell motility and secretion 94987570 Common - hypothetical protein LI1128 25 COG4866 COG4866, Uncharacterized conserved protein Function unknown 94987146 Common asnC asparaginyl-tRNA synthetase LI0704 246 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 94987110 Pathogen - NA LI0668 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 94986724 Common ackA acetate kinase LI0280 162 COG0282 ackA, Acetate kinase Energy production and conversion 94987018 Common trmA similar to RNA methyltransferase LI0576 197 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 94987615 Common - 3264: Small-conductance mechanosensitive channel LI1173 223 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 94987002 Common rpsI 30S ribosomal protein S9 LI0560 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 94987138 Common rubY Rubrerythrin LI0696 80 COG1592 COG1592, Rubrerythrin Energy production and conversion 94986461 Common - hypothetical protein LI0016 150 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 94987404 Common rplW 50S ribosomal protein L23 LI0962 202 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 94987220 Common nth endonuclease III, putative LI0778 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 94986678 Common - ABC-type transport system involved in resistance to organic solvents, auxiliary component LI0234 61 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 94986825 Common lgtF Glycosyltransferases involved in cell wall biogenesis LI0381 96 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 94987230 Common - membrane proteins related to metalloendopeptidases LI0788 191 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 94986991 Common yscS probable translocation protein in type III secretion LI0549 113 COG4794 EscS, Type III secretory pathway, component EscS Intracellular trafficking and secretion 94986454 Pathogen - NA LI0009 1 None None None 94986606 Common fabH 3-oxoacyl-[acyl-carrier-protein] synthase III LI0162 206 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 94986983 Common sctL type III secretion system protein LI0541 34 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 94987120 Common - 2-methylthioadenine synthetase LI0678 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 94987272 Common potB ABC-type spermidine/putrescine transport system, permease component I LI0830 206 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 94987039 Common - FOG: TPR repeat LI0597 88 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 94987522 Common - hypothetical protein LI1080 4 None None None 94986671 Common fabD (acyl-carrier-protein) S-malonyltransferase LI0227 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 94986809 Common - DNA uptake lipoprotein LI0365 97 COG4105 ComL, DNA uptake lipoprotein General function prediction only 94987329 Common - NA LI0887 2 None None None 94987256 Common soj ATPases involved in chromosome partitioning LI0814 225 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 94987216 Common trkA potassium transporter peripheral membrane component LI0774 177 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 94987065 Common rplU 50S ribosomal protein L21 LI0623 214 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 94986547 Common polB DNA polymerase I-3'-5' exonuclease and polymerase domains LI0102 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 94986733 Common - Pirin-related protein LI0289 147 COG1741 COG1741, Pirin-related protein General function prediction only 94987425 Common rplQ ribosomal protein L17 LI0983 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 94986727 Common - N6-adenine-specific methylase LI0283 211 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 94987055 Common sigB DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) LI0613 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 94987099 Common argH Argininosuccinate lyase LI0657 236 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 94987322 Common sfsA DNA-binding protein, stimulates sugar fermentation LI0880 106 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 94986847 Common atpB F0F1 ATP synthase subunit beta LI0403 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 94987032 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein LI0590 239 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 94987399 Common b2503 hypothetical protein LI0957 44 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 94987314 Common - hypothetical protein LI0872 48 COG2848 COG2848, Uncharacterized conserved protein Function unknown 94987348 Common hemL Glutamate-1-semialdehyde aminotransferase LI0906 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 94986530 Common dnaK Molecular chaperone dnaK LI0085 154 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 94986542 Common corA CorA, CorA-like Mg2+ transporter protein LI0097 145 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 94986800 Common - ATPase components of ABC transporters with duplicated ATPase domains LI0356 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 94986662 Common rpe Pentose-5-phosphate-3-epimerase LI0218 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 94986890 Pathogen - NA LI0447 1 None None None 94987341 Common - hypothetical protein LI0899 3 None None None 94986666 Common rplS ribonuclease HII LI0222 215 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 94986566 Common pepQ Xaa-Pro aminopeptidase LI0121 132 COG1739 COG1739, Uncharacterized conserved protein Function unknown 94987471 Common pstC phosphate transporter permease PstC LI1029 222 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 94986699 Pathogen - NA LI0255 1 None None None 94987411 Common rplN 50S ribosomal protein L14 LI0969 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 94986451 Pathogen - NA LI0006 1 None None None 94986526 Common - predicted nucleoside-diphosphate sugar epimerase LI0081 105 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 94987299 Common fliF Flagellar biosynthesis/type III secretory pathway lipoprotein LI0857 125 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 94987510 Common - NA LI1068 2 None None None 94987548 Common - UDP-N-acetylmuramate dehydrogenase LI1106 200 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 94987513 Common jag predicted RNA-binding protein LI1071 44 COG1847 Jag, Predicted RNA-binding protein General function prediction only 94986947 Common thiG thiazole synthase LI0504 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 94987392 Common - Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase LI0950 29 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 94986767 Common - Signal renition particle GTPase LI0323 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 94987087 Common htpX Zn-dependent protease with chaperone function LI0645 188 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 94987113 Common serA phosphoglycerate dehydrogenase and related dehydrogenases LI0671 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 94986744 Common glyQ glycyl-tRNA synthetase subunit alpha LI0300 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 94986802 Common - asmA protein LI0358 22 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 94987296 Common fliI Flagellar biosynthesis/type III secretory pathway ATPase LI0854 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 94987383 Common corC Putative Mg2+ and Co2+ transporter CorC LI0941 218 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 94987556 Common - Parvulin-like peptidyl-prolyl isomerase LI1114 168 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 94987305 Common cbiM cobalt transport protein CbiM LI0863 50 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 94987029 Common - hypothetical protein LI0587 5 None None None 94987480 Pathogen - NA LI1038 1 None None None 94986598 Common nusB transcription termination factor LI0153 182 COG0781 NusB, Transcription termination factor Transcription 94986760 Common - DnaJ-class molecular chaperone LI0316 137 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 94987015 Common - RimM protein, required for 16S rRNA processing LI0573 151 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 94987468 Common lolC ABC-type transport system, involved in lipoprotein release, permease component LI1026 174 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 94986476 Pathogen - NA LI0031 1 None None None 94987108 Pathogen - NA LI0666 1 None None None 94987040 Common zntA cation-transporting ATPase, P-type LI0598 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 94986570 Common - hypothetical protein LI0125 2 None None None 94987602 Common YscC putative type III secretion protein YscC LI1160 137 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 94987440 Common pyrE Orotate phosphoribosyltransferase LI0998 181 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 94986974 Common fliR Flagellar biosynthesis pathway, component FliR LI0532 129 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 94987447 Common truB Pseudouridine synthase LI1005 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 94986587 Pathogen - NA LI0142 1 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 94986656 Common thrS Threonyl-tRNA synthetase LI0212 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 94986839 Common - cell division protein FtsI/penicillin-binding protein 2 LI0395 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 94987020 Common purH AICAR transformylase/IMP cyclohydrolase PurH LI0578 214 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 94986817 Common pgsA Phosphatidylglycerophosphate synthase LI0373 207 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 94986771 Pathogen - NA LI0327 1 None None None 94986966 Common - hypothetical protein LI0523 2 None None None 94987598 Common - NA LI1156 2 None None None 94987477 Pathogen - NA LI1035 1 None None None 94987160 Common glnQ ABC-type polar amino acid transport system, ATPase component LI0718 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 94986618 Pathogen - NA LI0174 1 None None None 94987169 Common - NA LI0727 2 None None None 94986684 Common folk 7,8-dihydro-6-hydroxymethylpterin- pyrophosphokinase LI0240 192 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 94987058 Common radA DNA repair protein RadA LI0616 202 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 94986638 Common priA Primosomal protein N' (replication factor Y)-superfamily II helicase LI0194 211 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 94986907 Common pgk phosphoglycerate kinase LI0464 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 94986690 Common hypA Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) LI0246 82 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 94986958 Common ispB Geranylgeranyl pyrophosphate synthase LI0515 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 94987626 Common - uncharacterized homolog of PSP1 LI1184 58 COG1774 COG1774, Uncharacterized homolog of PSP1 Function unknown 94987551 Common ftsZ cell division protein FtsZ LI1109 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 94987287 Common - hypothetical protein LI0845 8 None None None 94986643 Common - Exoribonuclease R LI0199 186 COG0557 VacB, Exoribonuclease R Transcription 94987094 Common - DNA adenine methylase LI0652 96 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 94986790 Common htrA trypsin domain/PDZ domain protein LI0346 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 94987068 Common - similar to Escherichia coli possible protoporphyrinogen oxidase (hemK) LI0626 215 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 94986557 Common - hypothetical protein LI0112 34 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 94986527 Common - unknown conserved protein LI0082 16 COG1988 COG1988, Predicted membrane-bound metal-dependent hydrolases General function prediction only 94986879 Common - PhyA2 LI0436 11 None None None 94987491 Common - NA LI1049 2 None None None 94986700 Common - hypothetical protein LI0256 10 None None None 94986924 Common - hypothetical protein LI0481 8 COG1433 COG1433, Uncharacterized conserved protein Function unknown 94987461 Common lpxA UDP-N-acetylglucosamine acyltransferase LI1019 147 COG1043 LpxA, Acyl- acyl carrier protein 94987284 Common katE hydroperoxidase II LI0842 126 COG0753 KatE, Catalase Inorganic ion transport and metabolism 94986707 Common - putative amino acid-amine transport protein LI0263 164 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 94987535 Common - Outer membrane protein and related peptidoglycan-associated (lipo)proteins LI1093 25 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 94986493 Common secD preprotein translocase subunit SecD LI0048 218 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 94987360 Common recR Recombinational DNA repair protein (RecF pathway) ref|ZP_00131299.1| 353: Recombinational DNA repair protein (RecF pathway) LI0918 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 94987375 Common rplK 50S ribosomal protein L11 LI0933 249 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 94986918 Common - blr5158 LI0475 21 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 94986553 Common dapA Dihydrodipicolinate synthase/N-acetylneuraminate lyase LI0108 233 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 94986998 Common - Permeases of the major facilitator superfamily LI0556 212 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 94987572 Common - ribosomal protein L11 methylase LI1130 174 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 94987335 Common - Protein chain release factor B LI0893 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 94987312 Common - hypothetical protein LI0870 45 COG2121 COG2121, Uncharacterized protein conserved in bacteria Function unknown 94987346 Common rpoB DNA-directed RNA polymerase, beta subunit/140 kD subunit LI0904 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 94987077 Common paaK Coenzyme F390 synthetase LI0635 107 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 94986843 Common atpF F0F1-type ATP synthase, subunit b LI0399 24 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 94987573 Common secG preprotein translocase subunit SecG LI1131 14 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 94986603 Common glyA Glycine/serine hydroxymethyltransferase LI0159 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 94987324 Common - predicted permeases LI0882 136 COG0795 COG0795, Predicted permeases General function prediction only 94987456 Common - hypothetical protein LI1014 184 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 94987223 Common - 5-enolpyruvylshikimate-3-phosphate synthase LI0781 2 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 94987524 Common feoA Fe2+ transport system protein A LI1082 53 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 94987459 Common - hypothetical protein LI1017 3 None None None 94986894 Common pyrG CTP synthetase LI0451 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 94986823 Common galE nucleoside-diphosphate-sugar epimerases LI0379 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 94987014 Common - hypothetical protein LI0572 2 None None None 94987195 Common glnP ABC-type amino acid transport system, permease component LI0753 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 94986669 Common smpB SsrA-binding protein LI0225 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 94986756 Common - FOG: TPR repeat LI0312 24 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 94986815 Common - hypothetical protein LI0371 3 None None None 94986584 Pathogen - hypothetical protein LI0139 1 None None None 94986931 Common accC Biotin carboxylase LI0488 222 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 94987260 Common pyrB aspartate carbamoyltransferase catalytic subunit LI0818 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 94986864 Common bioB biotin synthase LI0420 183 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 94987022 Common - nucleoside-diphosphate-sugar epimerases LI0580 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 94987035 Common cls Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthases and related enzymes LI0593 146 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 94986628 Common - NA LI0184 2 None None None 94987038 Common tpx Peroxiredoxin LI0596 106 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 94986689 Common hypB hydrogenase accessory protein HypB LI0245 152 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 94986679 Common - Surface lipoprotein LI0235 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 94987628 Common ruvA Holliday junction resolvasome, DNA-binding subunit LI1186 210 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 94986452 Common tlc nucleotide transport protein LI0007 6 COG3202 COG3202, ATP/ADP translocase Energy production and conversion 94986914 Common - predicted xylanase/chitin deacetylase LI0471 78 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 94987566 Common nth endonuclease III, putative LI1124 112 COG2231 COG2231, Uncharacterized protein related to Endonuclease III DNA replication, recombination, and repair 94986708 Common rho transcription termination factor Rho LI0264 210 COG1158 Rho, Transcription termination factor Transcription 94986560 Common - hypothetical protein LI0115 2 None None None 94986719 Common cyoB Cytochrome bd-type quinol oxidase, subunit 1 LI0275 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 94987198 Common rnh Ribonuclease HI LI0756 174 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 94987106 Pathogen - NA LI0664 1 None None None 94987427 Common vc0389 putative Na+/H+ antiporter LI0985 67 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 94986990 Common yscV putative type III secretion pore protein LI0548 127 COG4789 EscV, Type III secretory pathway, component EscV Intracellular trafficking and secretion 94987438 Common - hypothetical protein LI0996 33 COG2331 COG2331, Uncharacterized protein conserved in bacteria Function unknown 94987239 Common - NA LI0797 2 None None None 94987145 Common - Exopolyphosphatase-related proteins LI0703 36 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 94987485 Common hprA Lactate dehydrogenase and related dehydrogenases LI1043 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 94986589 Common - SAM-dependent methyltransferases LI0144 45 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 94986660 Common pheT Phenylalanyl-tRNA synthetase beta subunit LI0216 244 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 94987000 Common - Competence protein ComGF LI0558 10 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 94986905 Common gltX Glutamyl-and glutaminyl-tRNA synthetases LI0462 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 94986892 Common - hypothetical protein LI0449 65 COG0327 COG0327, Uncharacterized conserved protein Function unknown 94987181 Common - NA LI0739 2 None None None 94986576 Common folC Folylpolyglutamate synthase LI0131 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 94986940 Common livH branched chain amino acid ABC transporter, permease protein LI0497 151 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 94986882 Common hyaA hydrogenase-1 small subunit LI0439 77 COG1740 HyaA, Ni,Fe-hydrogenase I small subunit Energy production and conversion 94987402 Common rplC 50S ribosomal protein L3 LI0960 218 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 94986842 Common - F0F1-type ATP synthase, subunit b LI0398 4 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 94986853 Common - predicted ATPase of the PP-loop superfamily implicated in cell cycle control LI0409 212 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 94986888 Common dtd D-tyrosyl-tRNA deacylase LI0445 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 94986783 Common - ABC-type branched-chain amino acid transport systems, periplasmic component LI0339 152 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 94987088 Common - N-methylhydantoinase A/acetone carboxylase, beta subunit LI0646 72 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 94986829 Common cdsA CDP-diglyceride synthetase LI0385 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 94986997 Common - hypothetical protein LI0555 2 None None None 94987309 Common murI Glutamate racemase LI0867 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 94987490 Common grpE Molecular chaperone GrpE (heat shock protein) LI1048 230 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 94986803 Common mgtE Mg/Co/Ni transporter MgtE (contains CBS domain) LI0359 173 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 94987240 Common - hypothetical protein LI0798 2 None None None 94986642 Common - predicted membrane protein LI0198 170 COG0344 COG0344, Predicted membrane protein Function unknown 94986832 Common - Inactive homolog of metal-dependent proteases, putative molecular chaperone LI0388 38 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 94987188 Common - hypothetical protein LI0746 2 None None None 94987205 Common fba Fructose/tagatose bisphosphate aldolase LI0763 178 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 94986549 Common - NA LI0104 2 None None None 94987545 Common spoVE Bacterial cell division membrane protein LI1103 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 94986957 Common - Na+/H+ antiporter NhaD and related arsenite permeases LI0514 27 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 94987498 Common - NA LI1056 2 None None None 94986775 Common amyA alpha-amylase LI0331 23 COG1449 COG1449, Alpha-amylase/alpha-mannosidase Carbohydrate transport and metabolism 94987463 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LI1021 164 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 94987362 Common - membrane proteins related to metalloendopeptidases LI0920 193 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 94987564 Common - hypothetical protein LI1122 67 COG2861 COG2861, Uncharacterized protein conserved in bacteria Function unknown 94986995 Common lysA Diaminopimelate decarboxylase LI0553 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 94986858 Common trpD Anthranilate phosphoribosyltransferase LI0414 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 94987355 Common aspA aspartate ammonia-lyase LI0913 234 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 94986712 Common ruvC Holliday junction resolvasome, endonuclease subunit LI0268 198 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 94986499 Common - rRNA methylases LI0054 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 94987353 Common - hypothetical protein LI0911 21 COG0730 COG0730, Predicted permeases General function prediction only 94987483 Pathogen - NA LI1041 1 None None None 94987429 Common aspS aspartyl-tRNA synthetase LI0987 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 94987323 Common - predicted permeases LI0881 69 COG0795 COG0795, Predicted permeases General function prediction only 94987538 Common mraZ hypothetical protein LI1096 134 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 94986702 Common - F0F1-type ATP synthase, subunit c LI0258 133 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 94986508 Common - NA LI0063 2 None None None 94987475 Pathogen - NA LI1033 1 None None None 94986518 Pathogen - NA LI0073 1 None None None 94986613 Common oppA ABC-type dipeptide transport system, periplasmic component LI0169 215 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 94986686 Common lig NAD-dependent DNA ligase (contains BRCT domain type II) LI0242 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 94987237 Common clpX ATP-dependent protease ATP-binding subunit LI0795 209 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 94987122 Common - predicted Fe-S-cluster redox enzyme LI0680 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 94987315 Common - ACT domain-containing protein LI0873 3 COG3830 COG3830, ACT domain-containing protein Signal transduction mechanisms 94986480 Common fur Fe2+/Zn2+ uptake regulation proteins LI0035 198 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 94986902 Common - hypothetical protein LI0459 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 94987126 Common - Acetyltransferase LI0684 47 COG0456 RimI, Acetyltransferases General function prediction only 94986734 Common - NA LI0290 5 None None None 94987111 Pathogen - NA LI0669 1 None None None 94987554 Common - Multimeric flavodoxin WrbA LI1112 36 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 94986979 Common SctR type III secretion system protein LI0537 128 COG4790 EscR, Type III secretory pathway, component EscR Intracellular trafficking and secretion 94986467 Common tyrS tyrosyl-tRNA synthetase LI0022 242 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 94986469 Common gcpE Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis LI0024 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 94987211 Common - hypothetical protein LI0769 157 COG1496 COG1496, Uncharacterized conserved protein Function unknown 94987372 Common rplL 50S ribosomal protein L7/L12 LI0930 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 94987101 Common - Shikimate kinase LI0659 25 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 94987302 Common flgB flagellar basal body rod protein FlgB LI0860 72 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 94987066 Common - GroES/HSP10 homolog LI0624 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 94986489 Common mdoB hypothetical protein LI0044 62 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 94986921 Common - Cytosine deaminase and related metal-dependent hydrolases LI0478 173 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 94987159 Common glnP ABC-type amino acid transport system, permease component LI0717 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 94987176 Common - NA LI0734 2 COG1988 COG1988, Predicted membrane-bound metal-dependent hydrolases General function prediction only 94986692 Common - NA LI0248 2 None None None 94986631 Common - hypothetical protein LI0187 15 COG4547 CobT, Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase) Coenzyme metabolism 94986758 Common pepP Xaa-Pro aminopeptidase LI0314 123 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 94986770 Common - predicted SAM-dependent methyltransferase LI0326 45 COG2933 COG2933, Predicted SAM-dependent methyltransferase General function prediction only 94987599 Common - regulatory protein PcrH LI1157 18 COG3726 AhpA, Uncharacterized membrane protein affecting hemolysin expression General function prediction only 94987505 Common - hypothetical protein LI1063 2 None None None 94987282 Pathogen - NA LI0840 1 None None None 94987218 Common psd phosphatidylserine decarboxylase LI0776 95 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 94986769 Common gltD NADPH-dependent glutamate synthase beta chain and related oxidoreductases LI0325 214 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 94986797 Common rplI 50S ribosomal protein L9 LI0353 216 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 94986490 Pathogen - NA LI0045 1 None None None 94986615 Common - NA LI0171 2 COG2839 COG2839, Uncharacterized protein conserved in bacteria Function unknown 94987147 Common - DedA protein family LI0705 163 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 94986762 Common - hypothetical protein LI0318 22 COG4641 COG4641, Uncharacterized protein conserved in bacteria Function unknown 94987364 Common purK phosphoribosylcarboxyaminoimidazole (NCAIR) mutase LI0922 229 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 94987298 Common fliG Flagellar motor switch protein LI0856 125 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 94986972 Common flhA flagellar biosynthesis protein A LI0530 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 94986742 Common - hypothetical protein LI0298 88 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 94987533 Common - hypothetical protein LI1091 81 COG1469 COG1469, Uncharacterized conserved protein Function unknown 94987171 Common cheV Chemotaxis signal transduction protein LI0729 213 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 94987384 Common rpsL 30S ribosomal protein S12 LI0942 246 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 94987519 Common - hypothetical protein LI1077 19 None None None 94986550 Common - hypothetical protein LI0105 12 None None None 94986586 Common nodB predicted xylanase/chitin deacetylase LI0141 64 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 94986912 Common - hypothetical protein LI0469 8 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 94986658 Common rplT 50S ribosomal protein L20 LI0214 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 94987140 Common rfaF ADP-heptose:LPS heptosyltransferase II LI0698 116 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 94987605 Common YscJ putative type III secretion protein LI1163 32 COG4669 EscJ, Type III secretory pathway, lipoprotein EscJ Intracellular trafficking and secretion 94986968 Common - Flagellar basal body-associated protein LI0525 3 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 94987085 Common - predicted enzyme with a TIM-barrel fold LI0643 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 94986982 Common sctN type III secretion system ATPase LI0540 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 94987162 Common lepA GTP-binding protein LepA LI0720 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 94986841 Common - Integral membrane protein CcmA involved in cell shape determination LI0397 73 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 94986565 Common - methionine sulfoxide reductase B LI0120 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 94987072 Common secA preprotein translocase subunit SecA LI0630 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 94986896 Common - Low specificity phosphatase (HAD superfamily) LI0453 105 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 94987414 Common rpsH 30S ribosomal protein S8 LI0972 217 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 94986559 Common serS seryl-tRNA synthetase LI0114 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 94987600 Common - NA LI1158 2 COG5613 COG5613, Uncharacterized conserved protein Function unknown 94987278 Common - predicted transcriptional regulator LI0836 37 COG2932 COG2932, Predicted transcriptional regulator Transcription 94986582 Common - putative integral membrane protein LI0137 10 None None None 94986955 Common - Sugar transferases involved in lipopolysaccharide synthesis LI0512 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 94987275 Common - hypothetical protein NMA1314 LI0833 25 COG4383 COG4383, Mu-like prophage protein gp29 Function unknown 94987526 Common glpC sn-glycerol-3-phosphate dehydrogenase subunit C LI1084 161 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 94986821 Common rpsB 30S ribosomal protein S2 LI0377 233 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 94986933 Common - hypothetical protein LI0490 3 None None None 94986505 Common glpR transcriptional regulators of sugar metabolism LI0060 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 94986543 Common - hypothetical protein LI0098 8 None None None 94986754 Common gmk Guanylate kinase LI0310 213 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 94986533 Common dut dUTPase LI0088 176 COG0756 Dut, dUTPase Nucleotide transport and metabolism 94986827 Common rrf Ribosome recycling factor LI0383 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 94987024 Common - phosphopantothenoylcysteine synthetase/decarboxylase LI0582 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 94986980 Common - putative translocation protein in type III secretion LI0538 3 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 94986862 Common - hypothetical protein LI0418 52 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 94986805 Common - quinolinate synthetase LI0361 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 94986926 Common motB Flagellar motor protein LI0483 148 COG1360 MotB, Flagellar motor protein Cell motility and secretion 94987134 Common tolB Periplasmic component of the Tol biopolymer transport system LI0692 142 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 94986474 Pathogen - NA LI0029 1 None None None 94987213 Common rne Ribonucleases G and E LI0771 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 94986626 Common - putative recombination protein-phage associated LI0182 11 None None None 94987252 Common - Integral membrane protein, interacts with FtsH LI0810 132 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 94987344 Common - outer membrane protein LI0902 140 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 94986939 Common - branched chain amino acid ABC transporter, periplasmic amino acid-binding protein LI0496 134 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 94987319 Common atoC Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains LI0877 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 94987259 Common hemN Coproporphyrinogen III oxidase and related Fe-S oxidoreductases LI0817 206 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 94987416 Common rplR 50S ribosomal protein L18 LI0974 214 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 94987310 Common rluB 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases LI0868 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 94987575 Common rimJ Acetyltransferases LI1133 181 COG0456 RimI, Acetyltransferases General function prediction only 94986601 Common ribE riboflavin synthase subunit alpha LI0156 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 94986713 Common yebC hypothetical protein LI0269 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 94986675 Common - ABC-type transport system involved in resistance to organic solvents, permease component LI0231 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 94986844 Common atpE F1F0-ATPase delta subunit LI0400 120 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 94987342 Common - predicted metal-dependent hydrolase LI0900 11 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 94987051 Common rpiB Ribose 5-phosphate isomerase RpiB LI0609 128 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 94986514 Pathogen - NA LI0069 1 None None None 94986654 Common fliS Flagellin-specific chaperone FliS LI0210 81 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 94986459 Common - recombination factor protein RarA LI0014 231 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 94987458 Common - hypothetical protein LI1016 2 None None None 94987543 Common mraY UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase LI1101 214 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 94987262 Common - 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) LI0820 180 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 94986578 Common - NA LI0133 2 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 94987246 Common - hypothetical protein LI0804 13 COG0700 SpmB, Uncharacterized membrane protein Function unknown 94986884 Common hyaC Probable Ni/Fe-hydrogenase 1 B-type cytochrome subunit LI0441 39 COG1969 HyaC, Ni,Fe-hydrogenase I cytochrome b subunit Energy production and conversion 94986648 Common - predicted Fe-S oxidoreductases LI0204 181 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 94987614 Common - NA LI1172 2 None None None 94986781 Common livM branched chain amino acid ABC transporter, permease protein LI0337 157 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 94987496 Common cheZ Chemotaxis protein LI1054 15 COG3143 CheZ, Chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 94987079 Common mutM Formamidopyrimidine-DNA glycosylase LI0637 180 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 94987186 Common flgI flagellar basal body P-ring protein LI0744 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 94987157 Common rluD Pseudouridylate synthases, 23S RNA-specific LI0715 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 94987007 Common - hypothetical protein LI0565 2 None None None 94986720 Common cyoA Cytochrome bd-type quinol oxidase, subunit 2 LI0276 155 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 94986794 Common fabI Enoyl-[acyl-carrier-protein] reductase (NADH) LI0350 232 COG0623 FabI, Enoyl- acyl-carrier-protein 94986524 Common - inner membrane component of binding-protein-dependent transport system LI0079 151 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 94986773 Common glgX Glyen debranching enzyme LI0329 34 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 94986709 Common - Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes LI0265 241 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 94987119 Common - hypothetical protein LI0677 2 COG2932 COG2932, Predicted transcriptional regulator Transcription 94987203 Common cbf1 predicted HD-superfamily hydrolase LI0761 46 COG3481 COG3481, Predicted HD-superfamily hydrolase General function prediction only 94987381 Common carB Carbamoylphosphate synthase large subunit (split gene in MJ) LI0939 235 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 94986988 Common - NA LI0546 3 None None None 94987143 Common uvrC Nuclease subunit of the excinuclease complex LI0701 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 94987420 Common map Methionine aminopeptidase LI0978 248 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 94986738 Common fumA fumarate hydratase LI0294 148 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 94987604 Pathogen - NA LI1162 1 None None None 94987306 Common - NA LI0864 3 COG5266 CbiK, ABC-type Co2+ transport system, periplasmic component Inorganic ion transport and metabolism 94987269 Common - hypothetical lipoprotein LI0827 6 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 94987580 Common - NA LI1138 53 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 94986765 Common resC ABC-type transport system involved in cytochrome c biogenesis, permease component LI0321 93 COG4137 COG4137, ABC-type uncharacterized transport system, permease component General function prediction only 94986465 Common trpS tryptophanyl-tRNA synthetase LI0020 248 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 94987115 Common thiL Thiamine monophosphate kinase LI0673 194 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 94987193 Common - Mg chelatase-related protein LI0751 191 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 94987291 Common - predicted hydrolases of HD superfamily LI0849 28 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 94986611 Common - Peptidyl-prolyl cis-trans isomerase (rotamase)-cyclophilin family LI0167 196 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 94986874 Common himA Bacterial nucleoid DNA-binding protein LI0431 159 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 94986633 Common folP Dihydropteroate synthase and related enzymes LI0189 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 94987124 Common ddlA D-alanine-D-alanine ligase and related ATP-grasp enzymes LI0682 211 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 94987370 Common tgt Queuine/archaeosine tRNA-ribosyltransferase LI0928 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 94986482 Common - predicted transcriptional regulators LI0037 14 COG1395 COG1395, Predicted transcriptional regulator Transcription 94986694 Common oppC ABC-type dipeptide/oligopeptide/nickel transport systems, permease components LI0250 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 94987178 Common prsA phosphoribosylpyrophosphate synthetase LI0736 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 94987300 Common fliE Flagellar hook-basal body protein LI0858 65 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 94987379 Common thiC thiamine biosynthesis protein ThiC LI0937 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 94987060 Common - ATPases with chaperone activity, ATP-binding subunit LI0618 247 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 94986688 Common nadE NH(3)-dependent NAD(+) synthetase LI0244 225 COG0171 NadE, NAD synthase Coenzyme metabolism 94987351 Common lgt Prolipoprotein diacylglyceryltransferase LI0909 208 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 94987196 Common glnH ABC-type amino acid transport/signal transduction systems, periplasmic component/domain LI0754 187 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 94987394 Common - hypothetical protein LI0952 2 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 94987503 Common - hypothetical protein LI1061 11 COG3334 COG3334, Uncharacterized conserved protein Function unknown 94987593 Common - transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains LI1151 168 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 94987049 Common - Putative Zn-dependent protease, contains TPR repeats LI0607 144 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 94986749 Common - transcription-repair coupling factor (superfamily II helicase) LI0305 212 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 94987280 Common murA UDP-N-acetylglucosamine enolpyruvyl transferase LI0838 209 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 94987128 Common pepA Leucyl aminopeptidase LI0686 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 94987422 Common rpsK 30S ribosomal protein S11 LI0980 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 94986516 Pathogen - NA LI0071 1 None None None 94987285 Common tsr Methyl-accepting chemotaxis protein LI0843 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 94987358 Common dnaX DNA polymerase III, gamma/tau subunits LI0916 246 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 94986704 Common ntrY Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation LI0260 222 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 94986903 Common - putative outer membrane protein LI0460 109 COG1881 COG1881, Phospholipid-binding protein General function prediction only 94987536 Common - HD-GYP domain LI1094 114 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 94987531 Common - predicted methyltransferase LI1089 19 COG3897 COG3897, Predicted methyltransferase General function prediction only 94987235 Common - FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) LI0793 213 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 94986928 Common - Permeases of the major facilitator superfamily LI0485 206 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 94986497 Common pfp diphosphate--fructose-6-phosphate 1-phosphotransferase LI0052 161 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 94986872 Common hemN Coproporphyrinogen III oxidase and related Fe-S oxidoreductases LI0429 129 COG1243 ELP3, Histone acetyltransferase Transcription / Chromatin structure and dynamics 94987431 Common - 3-deoxy-manno-octulosonate cytidylyltransferase LI0989 142 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 94987460 Common rfaQ ADP-heptose:LPS heptosyltransferase LI1018 54 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 94987339 Common araJ protein AraJ LI0897 167 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 94986807 Common - predicted integral membrane protein LI0363 37 COG0762 COG0762, Predicted integral membrane protein Function unknown 94987444 Common nrfA Chain A, Cytochrome C Nitrite Reductase LI1002 40 COG3303 NrfA, Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit Inorganic ion transport and metabolism 94987225 Common - hypothetical protein LI0783 2 None None None 94986447 Common prfA peptide chain release factor 1 LI0002 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 94986977 Common infB translation initiation factor 2 (IF-2; GTPase) LI0535 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 94987074 Common - Permeases of the major facilitator superfamily LI0632 219 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 94987257 Common spo0J predicted transcriptional regulators LI0815 187 COG1475 Spo0J, Predicted transcriptional regulators Transcription 94987091 Pathogen - NA LI0649 1 None None None 94986574 Common - amino acid ABC transporter, periplasmic amino acid-binding protein LI0129 163 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 94986946 Common - predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) LI0503 164 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 94987494 Common lsp Lipoprotein signal peptidase LI1052 191 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 94986788 Common - hypothetical protein LI0344 5 None None None 94986599 Common ribH Riboflavin synthase beta-chain LI0154 228 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 94987011 Common - ADP-heptose:LPS heptosyltransferase LI0569 25 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 94987250 Common comA putative hydrolase, haloacid dehalogenase-like hydrolase LI0808 69 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 94987409 Common rplP 50S ribosomal protein L16 LI0967 222 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 94986868 Common bioD Dethiobiotin synthetase LI0425 152 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 94986970 Common fleN ATPases involved in chromosome partitioning LI0528 240 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 94986795 Common mdh malate dehydrogenase LI0351 183 COG0281 SfcA, Malic enzyme Energy production and conversion 94986899 Common - ABC-type (unclassified) transport system, ATPase component LI0456 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 94987082 Common - Flagellar biogenesis protein LI0640 2 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 94986764 Common cysG Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) LI0320 140 COG1648 CysG, Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) Coenzyme metabolism 94987400 Common yhdP Hemolysins and related proteins containing CBS domains LI0958 216 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 94987562 Common proC Pyrroline-5-carboxylate reductase LI1120 213 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 94987044 Common - predicted metal dependent hydrolases LI0602 134 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 94986592 Common - Outer membrane lipoprotein LI0147 12 COG3133 SlyB, Outer membrane lipoprotein Cell envelope biogenesis, outer membrane 94986710 Common iscU NifU homolog involved in Fe-S cluster formation LI0266 145 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 94986834 Common proS prolyl-tRNA synthetase LI0390 249 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 94987132 Common - hypothetical protein LI0690 3 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 94987386 Common fusA elongation factor G LI0944 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 94986900 Common rpoN DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog LI0457 145 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 94987577 Common mreB Actin-like ATPase involved in cell morphogenesis LI1135 232 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 94987164 Pathogen - NA LI0722 1 COG4468 GalT, Galactose-1-phosphate uridyltransferase Carbohydrate transport and metabolism 94986472 Common fliM Flagellar motor switch protein LI0027 109 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 94987366 Common qacE membrane transporters of cations and cationic drugs LI0924 18 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 94987517 Common ncd2 Dioxygenases related to 2-nitropropane dioxygenase LI1075 139 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 94987508 Common rfbB dTDP-D-glucose 4,6-dehydratase LI1066 232 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane