Rhizobium etli CFN 42, complete genome NC_007761 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 86356252 Common - probable transcriptional regulator protein, TetR family RHE_CH00601 83 COG1309 AcrR, Transcriptional regulator Transcription 86356737 Common - hypothetical protein RHE_CH01094 5 None None None 86357402 Common - putative acetyltransferase protein RHE_CH01772 30 None None None 86355849 Common - probable sugar ABC transporter, permease protein RHE_CH00190 119 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 86356805 Common - putative aminopeptidase protein RHE_CH01165 31 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 86357580 Common - hypothetical protein RHE_CH01959 12 None None None 86358539 Common - hypothetical protein RHE_CH02937 5 None None None 86358471 Common lyc glycoside hydrolase protein RHE_CH02868 45 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 86356581 Common aroC chorismate synthase RHE_CH00935 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 86356648 Nonpathogen - hypothetical protein RHE_CH01002 1 None None None 86358180 Common - probable chloride peroxidase protein RHE_CH02571 87 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 86357054 Common - putative peptidoglycan binding protein (LysM domain involved in cell wall degradation) RHE_CH01416 26 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 86356244 Common - probable transcriptional regulator protein, LysR family RHE_CH00593 179 COG0583 LysR, Transcriptional regulator Transcription 86356426 Common - probable insertion sequence transposase protein RHE_CH00777 59 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 86359197 Common rpsU 30S ribosomal protein S21 RHE_CH03607 40 None None None 86358653 Common - hypothetical protein RHE_CH03051 44 COG3816 COG3816, Uncharacterized protein conserved in bacteria Function unknown 86359305 Common nrdF ribonucleotide-diphosphate reductase subunit beta RHE_CH03715 144 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 86359045 Common serA D-3-phosphoglycerate dehydrogenase protein RHE_CH03454 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 86359472 Common mdh malate dehydrogenase RHE_CH03891 202 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 86356758 Nonpathogen - hypothetical protein RHE_CH01116 1 None None None 86359460 Common xerC site-specific tyrosine recombinase XerC RHE_CH03879 224 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 86357195 Common - hypothetical protein RHE_CH01558 16 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 86359627 Common - putative glycosyltransferase protein RHE_CH04048 38 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 86358855 Common thuAch trehalosemaltose utilization protein RHE_CH03256 19 COG4813 ThuA, Trehalose utilization protein Carbohydrate transport and metabolism 86355703 Common chvG two-component sensor histidine kinase protein RHE_CH00035 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 86355882 Common - hypothetical protein RHE_CH00223 3 None None None 86356195 Common - hypothetical protein RHE_CH00542 53 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 86356541 Common ubiA prenyltransferase RHE_CH00895 196 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 86359051 Common - hypothetical protein RHE_CH03460 103 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 86356542 Common - hypothetical protein RHE_CH00896 12 None None None 86358237 Common - hypothetical protein RHE_CH02630 3 None None None 86357877 Common bcp bacterioferritin comigratory protein RHE_CH02262 207 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 86357069 Common - putative amino acid efflux protein, LysE family RHE_CH01431 115 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 86358647 Common - hypothetical protein RHE_CH03045 9 None None None 86359157 Common gltB glutamate synthase large subunit protein RHE_CH03566 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 86358387 Common nthA nitrile hydratase alpha subunit protein RHE_CH02783 21 None None None 86359589 Common hisCch3 histidinol-phosphate aminotransferase RHE_CH04010 233 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 86357831 Common - hypothetical conserved membrane protein RHE_CH02215 24 COG3821 COG3821, Predicted membrane protein Function unknown 86357265 Nonpathogen - hypothetical protein RHE_CH01631 8 None None None 86358393 Common ilvH acetolactate synthase 3 regulatory subunit RHE_CH02789 188 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 86358199 Nonpathogen - hypothetical protein RHE_CH02592 2 None None None 86358646 Common - probable sodium-dependent phosphate transporter protein RHE_CH03044 66 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 86359032 Common - putative sensory box/GGDEF family protein RHE_CH03440 176 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 86358923 Common braE amino acid ABC transporter, permease protein RHE_CH03325 149 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 86359234 Common - probable sugar ABC transporter, substrate-binding protein RHE_CH03644 93 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86359289 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase RHE_CH03699 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 86356702 Common - hypothetical protein RHE_CH01058 25 COG4898 COG4898, Uncharacterized protein conserved in bacteria Function unknown 86356784 Common - hypothetical protein RHE_CH01142 37 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 86358965 Nonpathogen - hypothetical protein RHE_CH03367 1 None None None 86357436 Nonpathogen - hypothetical protein RHE_CH01807 1 None None None 86358429 Common - hypothetical conserved membrane protein RHE_CH02826 3 COG4541 COG4541, Predicted membrane protein Function unknown 86356168 Common phoB phosphate regulon, two-component response regulator protein RHE_CH00514 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 86356398 Common - probable hemolysin protein RHE_CH00749 23 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 86357569 Common ntrC nitrogen regulation (two-component response regulator) protein RHE_CH01948 221 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 86358872 Common rpoE4 RNA polymerase sigma factor RHE_CH03273 171 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 86358784 Common - hypothetical protein RHE_CH03184 63 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 86357595 Common - probable transport secretion system IV, VirD4 protein RHE_CH01975 68 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 86359280 Common osmC osmotically inducible protein RHE_CH03690 76 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 86357235 Nonpathogen - hypothetical protein RHE_CH01598 1 None None None 86359248 Common - hypothetical protein RHE_CH03658 3 None None None 86356875 Common - probable phosphinothricin acetyltransferase (antibiotic resistance) protein RHE_CH01235 131 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 86359167 Nonpathogen - hypothetical protein RHE_CH03577 1 None None None 86356164 Common pstC phosphate ABC transporter, permease protein RHE_CH00510 227 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 86358615 Common - putative hydrolase protein RHE_CH03013 213 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 86355806 Common - probable penicillin binding protein RHE_CH00146 203 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 86355975 Common dnaN DNA polymerase III subunit beta RHE_CH00318 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 86358956 Common - probable transcriptional regulator protein, MarR family RHE_CH03358 117 COG1846 MarR, Transcriptional regulators Transcription 86357097 Common - putative peptidase protein RHE_CH01459 111 COG1505 COG1505, Serine proteases of the peptidase family S9A Amino acid transport and metabolism 86357940 Common - hypothetical protein RHE_CH02325 49 COG2313 IndA, Uncharacterized enzyme involved in pigment biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 86356458 Common lpxQ lipid A oxidase (involved in formation of 2-aminogluconate) protein RHE_CH00812 2 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 86358530 Nonpathogen - hypothetical protein RHE_CH02928 1 None None None 86357484 Nonpathogen - hypothetical protein RHE_CH01858 1 None None None 86359463 Common lpdAch2 dihydrolipoamide dehydrogenase RHE_CH03882 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 86355747 Common - probable sugar ABC transporter, ATP binding protein RHE_CH00086 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 86357292 Common nusG transcription antitermination protein NusG RHE_CH01662 215 COG0250 NusG, Transcription antiterminator Transcription 86357686 Common - hypothetical protein RHE_CH02067 5 None None None 86359147 Common hemH ferrochelatase RHE_CH03556 153 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 86356184 Common - hypothetical protein RHE_CH00531 9 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 86358662 Common - probable acetyltransferase protein RHE_CH03060 77 COG3153 COG3153, Predicted acetyltransferase General function prediction only 86358190 Common - probable transcriptional regulator protein RHE_CH02582 68 COG1309 AcrR, Transcriptional regulator Transcription 86359637 Common sfuC iron(III) ABC transporter, ATP-binding protein RHE_CH04058 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 86356586 Common - hypothetical protein RHE_CH00940 7 None None None 86357015 Common - probable toxin secretion ABC transporter, ATP-binding protein RHE_CH01377 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 86359424 Common - putative sugar ABC transporter, permease protein RHE_CH03842 135 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 86359540 Common rimM 16S rRNA-processing protein RHE_CH03960 106 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 86355868 Common - probable pilus assembly protein RHE_CH00209 87 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 86356386 Common dppBch1 dipeptide ABC transporter, permease protein RHE_CH00737 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 86356684 Common - hypothetical protein RHE_CH01040 37 COG3791 COG3791, Uncharacterized conserved protein Function unknown 86356889 Common rosR transcriptional regulator protein - nodulation competitiveness determinant RHE_CH01249 34 COG4957 COG4957, Predicted transcriptional regulator Transcription 86358130 Common - putative copper-containing oxidase protein RHE_CH02519 130 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 86357299 Common - hypothetical protein RHE_CH01669 6 None None None 86358445 Common ftsQ cell division protein RHE_CH02842 81 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 86357060 Common - hypothetical protein RHE_CH01422 68 COG3791 COG3791, Uncharacterized conserved protein Function unknown 86356350 Common aglA alpha-glucosidase protein RHE_CH00699 161 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 86357553 Common - putative septum formation initiator protein RHE_CH01932 31 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 86355831 Common - probable multidrug ABC transporter, ATP binding protein RHE_CH00171 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 86358160 Common - hypothetical protein RHE_CH02551 43 COG5267 COG5267, Uncharacterized protein conserved in bacteria Function unknown 86356718 Common - hypothetical protein RHE_CH01075 65 COG3832 COG3832, Uncharacterized conserved protein Function unknown 86356021 Common hrcA heat-inducible transcription repressor RHE_CH00364 148 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 86359662 Common - putative nucleotidyltransferase protein RHE_CH04084 95 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 86357062 Common - hypothetical protein RHE_CH01424 45 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 86357848 Common - hypothetical protein RHE_CH02233 2 None None None 86358107 Common - putative amino acid ABC transporter, substrate-binding protein RHE_CH02495 22 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 86359549 Common - putative cAMP-dependent kinase protein RHE_CH03969 48 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 86355874 Common - probable insertion sequence transposase protein, ISRm2011-2 RHE_CH00215 46 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 86358167 Common - hypothetical protein RHE_CH02558 7 None None None 86358176 Nonpathogen - hypothetical protein RHE_CH02567 1 None None None 86356484 Common - hypothetical protein RHE_CH00838 11 None None None 86359704 Common hemE uroporphyrinogen decarboxylase RHE_CH04126 176 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 86356574 Common bioY biotin transporter protein RHE_CH00928 102 COG1268 BioY, Uncharacterized conserved protein General function prediction only 86356778 Common betA choline dehydrogenase RHE_CH01136 94 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 86355842 Nonpathogen - hypothetical protein RHE_CH00182 1 None None None 86356445 Common - probable transcriptional regulator protein, TetR family RHE_CH00799 23 COG1309 AcrR, Transcriptional regulator Transcription 86356921 Common - probable transcriptional regulator protein, TetR family RHE_CH01281 37 COG1309 AcrR, Transcriptional regulator Transcription 86357384 Common gpt xanthine-guanine phosphoribosyltransferase RHE_CH01754 92 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 86358936 Common - hypothetical protein RHE_CH03338 29 COG1579 COG1579, Zn-ribbon protein, possibly nucleic acid-binding General function prediction only 86359007 Common potD spermidine/putrescine ABC transporter, substrate-binding protein RHE_CH03415 64 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 86356145 Common - probable zinc-type alcohol dehydrogenase protein RHE_CH00489 202 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 86358338 Common - probable SAM-dependent methyltransferase protein RHE_CH02733 73 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 86357538 Common uppS undecaprenyl pyrophosphate synthase protein RHE_CH01917 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 86355809 Common - putative sensory box/GGDEF family protein RHE_CH00149 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 86357882 Common - putative regulator protein of competence-specific genes RHE_CH02267 28 COG3070 TfoX, Regulator of competence-specific genes Transcription 86357075 Common rplI 50S ribosomal protein L9 RHE_CH01437 215 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 86357181 Common celB cellulose synthase protein RHE_CH01543 9 None None None 86356299 Common - probable transcriptional regulator protein, LuxR family RHE_CH00648 5 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 86357052 Common clpP ATP-dependent Clp protease proteolytic subunit RHE_CH01414 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 86355686 Common - hypothetical protein RHE_CH00018 19 None None None 86356727 Nonpathogen ndiA3 nutrient deprivation-induced protein RHE_CH01084 5 None None None 86357679 Common dppAch2 dipeptide ABC transporter, substrate-binding protein RHE_CH02060 195 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 86358111 Common - probable amino acid efflux protein, LysE family RHE_CH02499 82 COG1279 COG1279, Lysine efflux permease General function prediction only 86358934 Common - hypothetical protein RHE_CH03336 30 COG5385 COG5385, Uncharacterized protein conserved in bacteria Function unknown 86356666 Common - hypothetical protein RHE_CH01021 11 COG4298 COG4298, Uncharacterized protein conserved in bacteria Function unknown 86359228 Common - probable rhodanese-related sulfurtransferase protein RHE_CH03638 108 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 86359630 Common - putative transcriptional regulator protein RHE_CH04051 30 COG1522 Lrp, Transcriptional regulators Transcription 86357717 Common - putative dithiol-disulfide isomerase protein (involved in polyketide biosynthesis) RHE_CH02098 86 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 86358001 Common - putative sensory box/GGDEF family protein RHE_CH02386 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 86359655 Common - putative metalloendopeptidase protein RHE_CH04077 110 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 86356714 Common - hypothetical protein RHE_CH01071 5 COG4766 EutQ, Ethanolamine utilization protein Amino acid transport and metabolism 86357151 Common rfbD dTDP-4-dehydrorhamnose reductase protein RHE_CH01513 163 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 86358084 Common - hypothetical protein RHE_CH02472 2 None None None 86355794 Nonpathogen - probable sugar ABC transporter, permease protein RHE_CH00134 1 None None None 86355970 Common - hypothetical protein RHE_CH00313 48 COG5470 COG5470, Uncharacterized conserved protein Function unknown 162329635 Common murC UDP-N-acetylmuramate--L-alanine ligase RHE_CH02846 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 86359111 Common - putative methyl-accepting chemotaxis protein RHE_CH03520 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 86357370 Common - hypothetical protein RHE_CH01740 4 None None None 86357495 Common accCch acetyl-CoA carboxylase biotin carboxylase subunit RHE_CH01869 235 COG0439 AccC, Biotin carboxylase Lipid metabolism 86355884 Common purU formyltetrahydrofolate deformylase RHE_CH00225 218 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 86358187 Common - hypothetical protein RHE_CH02578 83 COG1733 COG1733, Predicted transcriptional regulators Transcription 86355788 Common - putative NTP pyrophosphohydrolase protein, MutT/nudix family (responsible for removing an oxidativelydamaged form of guanine from DNA and the nucleotide pool) RHE_CH00128 103 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 86357921 Common - putative bicyclomycin resistance transporter protein RHE_CH02306 199 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86356906 Common - probable lactoylglutathione lyase protein RHE_CH01266 61 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 86358753 Common rhlE2 ATP-dependent RNA helicase protein RHE_CH03152 239 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 86356333 Common flaF flagellar biosynthesis regulatory protein FlaF RHE_CH00682 12 COG5442 FlaF, Flagellar biosynthesis regulator FlaF Cell motility and secretion 86359395 Common gloB hydroxyacylgluthatione hydrolase protein RHE_CH03812 177 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 86359221 Common - hypothetical protein RHE_CH03631 29 COG3683 COG3683, ABC-type uncharacterized transport system, periplasmic component General function prediction only 86355731 Common - probable cellulose synthase protein RHE_CH00070 67 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 86355771 Common pnp polynucleotide phosphorylase/polyadenylase RHE_CH00111 243 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 86358349 Common ilvC ketol-acid reductoisomerase RHE_CH02744 211 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 86358489 Common glnA3 glutamine synthetase protein RHE_CH02886 223 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 86359564 Common galE3 UDP-glucose 4-epimerase protein RHE_CH03985 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 86359536 Nonpathogen - hypothetical protein RHE_CH03956 1 None None None 86358924 Common braD amino acid ABC transporter, permease protein RHE_CH03326 157 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 86358656 Common - hypothetical protein RHE_CH03054 32 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 86358509 Common - probable spermidine/putrescine ABC transporter, permease protein RHE_CH02906 191 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 86357861 Nonpathogen - hypothetical protein RHE_CH02246 1 None None None 86356275 Common - probable two-component sensor histidine kinase/response regulator hybrid protein RHE_CH00624 225 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 86358567 Common - probable L-iditol 2-dehydrogenase protein RHE_CH02965 209 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 86356879 Common groEL chaperonin GroEL RHE_CH01239 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 86355915 Common - hypothetical protein RHE_CH00257 25 COG1633 COG1633, Uncharacterized conserved protein Function unknown 86355981 Nonpathogen - hypothetical protein RHE_CH00324 4 None None None 86356698 Nonpathogen - hypothetical protein RHE_CH01054 2 None None None 86356113 Common - hypothetical protein RHE_CH00457 27 COG4101 COG4101, Predicted mannose-6-phosphate isomerase Carbohydrate transport and metabolism 86358773 Common xylF xylose ABC transporter, substrate-binding protein RHE_CH03172 88 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 86358140 Nonpathogen - hypothetical protein RHE_CH02530 1 None None None 86357344 Common - putative esterase/lipase/thioesterase family protein RHE_CH01714 116 COG0657 Aes, Esterase/lipase Lipid metabolism 86356812 Nonpathogen - hypothetical protein RHE_CH01172 1 None None None 86357786 Common - putative transglutaminase-like protein RHE_CH02169 102 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 86359341 Common ptsP enzyme I of the phosphotransferase system RHE_CH03757 234 COG3605 PtsP, Signal transduction protein containing GAF and PtsI domains Signal transduction mechanisms 86358283 Common - putative efflux transporter protein RHE_CH02677 27 None None None 86359449 Common pssA3 exopolysaccharide production protein RHE_CH03868 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 86358256 Common - hypothetical protein RHE_CH02650 8 COG5439 COG5439, Uncharacterized conserved protein Function unknown 86357579 Common cysG uroporphyrin-III C-methyltransferase protein RHE_CH01958 204 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 86359400 Common - hypothetical protein RHE_CH03817 55 COG1738 COG1738, Uncharacterized conserved protein Function unknown 86357242 Common nuoE1 NADH dehydrogenase subunit E RHE_CH01608 157 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 86357504 Common thrA homoserine dehydrogenase RHE_CH01878 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 86357801 Common secG preprotein translocase subunit SecG RHE_CH02185 13 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 86358770 Common - hypothetical protein RHE_CH03169 9 None None None 86358311 Nonpathogen - hypothetical protein RHE_CH02705 1 None None None 86357315 Common rplN 50S ribosomal protein L14 RHE_CH01685 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 86357081 Common fabG2 3-ketoacyl-(acyl-carrier-protein) reductase NodG RHE_CH01443 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 86356560 Common - hypothetical protein RHE_CH00914 144 COG1741 COG1741, Pirin-related protein General function prediction only 86358350 Common - probable transcriptional regulator protein, TetR family RHE_CH02745 19 COG1309 AcrR, Transcriptional regulator Transcription 86358263 Common - probable sugar ABC transporter, ATP-binding protein RHE_CH02657 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 86355909 Common - probable acetyltransferase protein RHE_CH00251 28 COG0456 RimI, Acetyltransferases General function prediction only 86356366 Common potG spermidine/putrescine ABC transporter, ATP-binding protein RHE_CH00715 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 86357953 Common fdx ferredoxin, 2Fe-2S FDII electron transport iron-sulfur protein RHE_CH02338 58 COG0633 Fdx, Ferredoxin Energy production and conversion 86357416 Common gntR transcriptional regulator protein, LacI family RHE_CH01786 126 COG1609 PurR, Transcriptional regulators Transcription 86357765 Common ggt1 gamma-glutamyltranspeptidase protein RHE_CH02146 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 86358101 Common cobN cobaltochelatase RHE_CH02489 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 86355734 Common - probable sugar ABC transporter, substrate-binding protein RHE_CH00073 47 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86359294 Common - putative gluconolactonase protein RHE_CH03704 84 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 86357188 Common - hypothetical protein RHE_CH01551 11 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 86356013 Common fadB1 enoyl-CoA hydratase RHE_CH00356 187 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 86356569 Common - probable transcriptional regulator protein, LuxR family RHE_CH00923 31 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 86357736 Common tgt queuine tRNA-ribosyltransferase RHE_CH02117 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 86356606 Common - putative cytochrome oxidase complex biogenesis factor transmembrane protein RHE_CH00960 45 COG3346 COG3346, Uncharacterized conserved protein Function unknown 86355775 Common rbfA ribosome-binding factor A RHE_CH00115 88 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 86357442 Common exoR2 exopolysaccharide production negative regulator protein RHE_CH01814 41 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 86356532 Common purD phosphoribosylamine--glycine ligase RHE_CH00886 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 86357115 Common moaD molybdopterin converting factor subunit 1 protein RHE_CH01477 25 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 86358358 Common ugpCch1 sn-glycerol-3-phosphate ABC transporter, ATP-binding protein RHE_CH02753 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 86356504 Nonpathogen - hypothetical protein RHE_CH00858 1 None None None 86356497 Common - hypothetical protein RHE_CH00851 3 COG1873 COG1873, Uncharacterized conserved protein Function unknown 86356477 Common ribF bifunctional riboflavin kinase/FMN adenylyltransferase RHE_CH00831 211 COG0196 RibF, FAD synthase Coenzyme metabolism 86358493 Common - probable ABC transporter, substrate-binding protein RHE_CH02890 51 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 86358694 Common braC1 amino acid ABC transporter, substrate-binding protein RHE_CH03093 148 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 86357253 Common birA biotin--[acetyl-CoA carboxylase] synthetase protein RHE_CH01619 220 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 86356236 Common infA translation initiation factor IF-1 RHE_CH00584 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 86357379 Common - hypothetical protein RHE_CH01749 19 None None None 86358121 Nonpathogen - hypothetical protein RHE_CH02509 1 None None None 86358036 Common - putative methyltransferase protein RHE_CH02423 25 COG4976 COG4976, Predicted methyltransferase (contains TPR repeat) General function prediction only 86359118 Common thiEch thiamine-phosphate pyrophosphorylase RHE_CH03527 38 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 86357218 Common - putative glyoxalase protein RHE_CH01581 5 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 86357862 Common - hypothetical protein RHE_CH02247 162 COG0316 IscA, Uncharacterized conserved protein Function unknown 86356973 Common - hypothetical protein RHE_CH01333 2 None None None 86356414 Common - hypothetical protein RHE_CH00765 28 None None None 86356825 Common zwf2 glucose-6-phosphate 1-dehydrogenase RHE_CH01185 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 86356051 Common - probable SAM-dependent methyltransferase protein RHE_CH00394 26 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 86357587 Common - putative site-specific recombinase, phage integrase family protein RHE_CH01967 12 None None None 86357651 Nonpathogen - hypothetical protein RHE_CH02032 2 None None None 86356221 Common aspB1 aspartate aminotransferase RHE_CH00568 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 86359130 Common - hypothetical protein RHE_CH03539 33 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 86356613 Common - hypothetical protein RHE_CH00967 54 COG4233 COG4233, Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis Posttranslational modification, protein turnover, chaperones / Energy production and conversion 86357711 Common - hypothetical protein RHE_CH02092 82 COG2928 COG2928, Uncharacterized conserved protein Function unknown 86355838 Common - probable peptide ABC transporter, ATP binding protein RHE_CH00178 249 COG4172 COG4172, ABC-type uncharacterized transport system, duplicated ATPase component General function prediction only 86355712 Nonpathogen - hypothetical protein RHE_CH00044 2 None None None 86358319 Common - probable cobalamin synthesis protein RHE_CH02713 129 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 86355967 Common upk undecaprenyl pyrophosphate phosphatase RHE_CH00310 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 86356630 Common - probable cytochrome-c oxidase protein RHE_CH00984 75 COG2863 COG2863, Cytochrome c553 Energy production and conversion 86359507 Common - putative ABC transporter, ATP-binding protein RHE_CH03927 249 COG1101 PhnK, ABC-type uncharacterized transport system, ATPase component General function prediction only 86358147 Common - probable mechanosensitive channel protein RHE_CH02537 213 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 86357718 Common - probable peptide ABC transporter, substrate-binding protein RHE_CH02099 180 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 86357301 Common rpsG 30S ribosomal protein S7 RHE_CH01671 237 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 86357808 Common - hypothetical protein RHE_CH02192 15 COG5330 COG5330, Uncharacterized protein conserved in bacteria Function unknown 86358092 Common - hypothetical protein RHE_CH02480 29 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 86356931 Common cycK cytochrome-c-type synthesis protein RHE_CH01291 148 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 86358060 Nonpathogen - hypothetical protein RHE_CH02448 1 None None None 86356309 Common flgB flagellar basal body rod protein FlgB RHE_CH00658 26 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 86358340 Common - putative L-sorbosone dehydrogenase protein RHE_CH02735 66 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 86358431 Common prmA ribosomal protein L11 methyltransferase RHE_CH02828 167 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 86356986 Common - probable ferredoxin reductase protein RHE_CH01347 201 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 86356085 Common argB acetylglutamate kinase RHE_CH00428 225 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 86358614 Common - hypothetical protein RHE_CH03012 14 COG4991 COG4991, Uncharacterized protein with a bacterial SH3 domain homologue Function unknown 86359454 Common atpH F0F1 ATP synthase subunit delta RHE_CH03873 180 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 86356531 Common - hypothetical protein RHE_CH00885 12 COG4907 COG4907, Predicted membrane protein Function unknown 86359074 Common - probable phosphohydrolase protein RHE_CH03483 91 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 86357033 Common - putative oxidoreductase protein RHE_CH01395 170 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 86356835 Common nadE NAD synthetase RHE_CH01195 135 COG0171 NadE, NAD synthase Coenzyme metabolism 86356004 Common hutUch urocanate hydratase RHE_CH00347 97 COG2987 HutU, Urocanate hydratase Amino acid transport and metabolism 86357233 Nonpathogen - hypothetical protein RHE_CH01596 1 None None None 86359316 Common - hypothetical protein RHE_CH03726 29 COG4321 COG4321, Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis General function prediction only 86359440 Common fdsG formate dehydrogenase subunit gamma RHE_CH03859 156 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 86358332 Common - probable transcriptional regulator protein, MarR family RHE_CH02727 107 COG1846 MarR, Transcriptional regulators Transcription 86356034 Common olsA 1-acyl-sn-glycerol-3-phosphate acyltransferase (phospholipid/glycerol acyltransferase) protein RHE_CH00377 98 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 86356611 Nonpathogen - hypothetical protein RHE_CH00965 1 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 86359108 Common cheW3 chemotaxis signal transduction protein RHE_CH03517 132 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 86357688 Common - probable sugar ABC transporter, permease protein RHE_CH02069 138 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 86357998 Common fumC fumarate hydratase RHE_CH02383 214 COG0114 FumC, Fumarase Energy production and conversion 86359101 Common - hypothetical protein RHE_CH03510 33 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 86355813 Common - hypothetical protein RHE_CH00153 43 COG2320 GrpB, Uncharacterized conserved protein Function unknown 86356239 Common - hypothetical protein RHE_CH00588 5 None None None 86357447 Common - hypothetical protein RHE_CH01819 18 None None None 86356391 Common - putative oxidoreductase protein RHE_CH00742 138 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 86357722 Common glnB nitrogen regulatory protein P-II RHE_CH02103 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 86356102 Nonpathogen - hypothetical protein RHE_CH00446 1 None None None 86357072 Common azlC branched-chain amino acid transporter protein (azaleucine resistance) RHE_CH01434 108 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 86357746 Common afuA2 iron(III) ABC transporter, substrate-binding protein RHE_CH02127 90 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 86358229 Nonpathogen - hypothetical protein RHE_CH02622 1 None None None 86356002 Common - putative transporter permease protein RHE_CH00345 100 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86358710 Common - hypothetical protein RHE_CH03109 27 COG4649 COG4649, Uncharacterized protein conserved in bacteria Function unknown 86358926 Common pssA2 exopolysaccharide production protein RHE_CH03328 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 86357540 Common - probable zinc metallopeptidase protein RHE_CH01919 219 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 86357290 Common - pprobable nucleoside-diphosphate-sugar epimerase protein RHE_CH01659 219 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 86358822 Common pssC glycosyltransferase protein RHE_CH03223 28 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 86356769 Nonpathogen - hypothetical protein RHE_CH01127 5 None None None 86358709 Common engA GTP-binding protein EngA RHE_CH03108 235 COG1160 COG1160, Predicted GTPases General function prediction only 86358400 Common hflC hydrolase serine protease transmembrane subunit C protein RHE_CH02796 123 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 86356364 Common - putative transcriptional regulator protein RHE_CH00713 45 COG3800 COG3800, Predicted transcriptional regulator General function prediction only 86358034 Common - putative phosphoribosylanthranilate isomerase subunit Usg protein RHE_CH02421 24 COG5425 COG5425, Usg protein, probable subunit of phosphoribosylanthranilate isomerase Amino acid transport and metabolism 86357161 Common - hypothetical protein RHE_CH01523 21 COG3837 COG3837, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 86357626 Nonpathogen - hypothetical protein RHE_CH02006 1 None None None 86356326 Common motC chemotaxis protein RHE_CH00675 11 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 86358990 Common - hypothetical protein RHE_CH03392 8 None None None 86359570 Common - putative membrane dipeptidase protein RHE_CH03991 104 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 86356696 Nonpathogen - hypothetical protein RHE_CH01052 2 None None None 86358361 Common - probable glycosyltransferase protein RHE_CH02756 157 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 86357638 Nonpathogen - hypothetical protein RHE_CH02018 1 None None None 86358282 Common - probable transcriptional regulator protein, LysR family RHE_CH02676 108 COG0583 LysR, Transcriptional regulator Transcription 86356035 Common fur ferric uptake regulation protein RHE_CH00378 193 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 86355824 Common phnJ C-P (carbon-phosphorus) lyase component protein RHE_CH00164 45 COG3627 PhnJ, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 86358459 Common mraZ hypothetical protein RHE_CH02856 25 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 86359365 Common - putative transmembrane-associated alkaline phosphatase protein RHE_CH03782 48 COG1238 COG1238, Predicted membrane protein Function unknown 86356945 Common - probable protein secretion protein, HlyD family RHE_CH01305 160 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 86357791 Common trpD anthranilate phosphoribosyltransferase RHE_CH02174 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 86357969 Common - probable FAD-dependent oxidoreductase protein RHE_CH02354 85 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 86357192 Common - probable sugar ABC transporter, substrate-binding protein RHE_CH01555 55 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86359602 Common - putative heat shock protein (ribosome-associated) RHE_CH04023 106 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 86359323 Common nuoM2 putative monovalent cation/H+ antiporter subunit D RHE_CH03733 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 86356064 Common ptsNch protein-N(pi)-phosphohistidine-sugar phosphotransferase protein (enzyme II of thephosphotransferase system) RHE_CH00407 138 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 86356429 Common - probable insertion sequence transposase protein RHE_CH00780 19 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 86357783 Nonpathogen - hypothetical protein RHE_CH02166 1 None None None 86359556 Common - 2-octaprenyl-6-methoxyphenyl hydroxylase RHE_CH03976 137 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 86356420 Common - putative fatty acid desaturase protein RHE_CH00771 25 COG3239 DesA, Fatty acid desaturase Lipid metabolism 86357424 Common ttuD hydroxypyruvate reductase protein RHE_CH01794 86 COG2379 GckA, Putative glycerate kinase Carbohydrate transport and metabolism 86358982 Nonpathogen - putative transcriptional regulator protein RHE_CH03384 6 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 86357127 Common - putative permease protein RHE_CH01489 181 COG0628 PerM, Predicted permease General function prediction only 86356639 Common - hypothetical protein RHE_CH00993 17 None None None 86357514 Nonpathogen - hypothetical protein RHE_CH01893 1 None None None 86358461 Common - probable sarcosine oxidase protein RHE_CH02858 17 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 86356511 Common atpE F0F1 ATP synthase subunit C RHE_CH00865 42 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 86356153 Common - probable ABC transporter, ATP-binding protein RHE_CH00497 249 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 86358550 Common - hypothetical protein RHE_CH02948 7 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 86355972 Common - hypothetical protein RHE_CH00315 18 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 86357450 Common - putative transcriptional regulator protein RHE_CH01822 130 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 86356009 Common hutHch histidine ammonia-lyase protein RHE_CH00352 109 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 86358368 Common - putative transcriptional regulator protein, MarR family RHE_CH02764 58 COG1846 MarR, Transcriptional regulators Transcription 86357555 Common pdhA2 pyruvate dehydrogenase subunit beta RHE_CH01934 203 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 86359014 Common - hypothetical protein RHE_CH03422 3 None None None 86359373 Common - hypothetical protein RHE_CH03790 131 COG2096 COG2096, Uncharacterized conserved protein Function unknown 86357303 Common tufA elongation factor Tu RHE_CH01673 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 86358702 Common - hypothetical protein RHE_CH03101 4 None None None 86358734 Common - putative phosphatase protein RHE_CH03133 22 COG2453 CDC14, Predicted protein-tyrosine phosphatase Signal transduction mechanisms 86356868 Common - putative polysaccharide deacetylase protein RHE_CH01228 24 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 86359191 Common soxAch sarcosine oxidase alpha subunit protein RHE_CH03601 182 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 86358321 Common - probable hemolysin protein RHE_CH02715 218 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 86356673 Common - putative nucleoside-diphosphate-sugar epimerase protein RHE_CH01029 107 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 86355680 Common - putative transcriptional regulator protein RHE_CH00011 12 COG1396 HipB, Predicted transcriptional regulators Transcription 86358596 Common - hypothetical protein RHE_CH02994 7 None None None 86355940 Common - probable transcriptional regulator protein, MarR family RHE_CH00282 20 COG1846 MarR, Transcriptional regulators Transcription 86358751 Common - probable transcriptional regulator protein, LacI family RHE_CH03150 128 COG1609 PurR, Transcriptional regulators Transcription 86358057 Common - hypothetical protein RHE_CH02445 13 COG3313 COG3313, Predicted Fe-S protein General function prediction only 86356353 Common edd phosphogluconate dehydratase RHE_CH00702 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 86358565 Common - probable transporter, permease protein RHE_CH02963 229 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86356625 Common thrC threonine synthase RHE_CH00979 163 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 86356956 Common bioA putative aminotransferase RHE_CH01316 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 86358050 Common - probable transcriptional regulator protein, AsnC family RHE_CH02438 140 COG1522 Lrp, Transcriptional regulators Transcription 86356596 Common tldD Zn-dependent protease protein RHE_CH00950 169 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 86358158 Common - hypothetical conserved membrane protein RHE_CH02549 7 None None None 86358543 Nonpathogen - hypothetical protein RHE_CH02941 3 None None None 86359273 Common smoC sorbitol/mannitol operon transcriptional regulator protein RHE_CH03683 64 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 86357501 Common phbC poly-beta-hydroxybutyrate polymerase protein RHE_CH01875 73 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 86358628 Common - putative sensory box/GGDEF family protein RHE_CH03026 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 86359022 Common - hypothetical protein RHE_CH03430 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 86359093 Common - hypothetical protein RHE_CH03502 2 None None None 86359378 Common tlpA thiol:disulfide interchange protein RHE_CH03795 132 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 86359043 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase RHE_CH03452 216 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 86356624 Common - probable processing protease protein RHE_CH00978 176 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 86358074 Common - probable transcriptional regulator protein, LacI family RHE_CH02462 85 COG1609 PurR, Transcriptional regulators Transcription 86359615 Common glmS2 glucosamine--fructose-6-phosphate aminotransferase protein RHE_CH04036 232 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 86358672 Common - hypothetical protein RHE_CH03070 27 COG3416 COG3416, Uncharacterized protein conserved in bacteria Function unknown 86359310 Common - putative transcriptional regulator protein, MerR family RHE_CH03720 140 COG0789 SoxR, Predicted transcriptional regulators Transcription 86357398 Common - hypothetical conserved membrane protein RHE_CH01768 77 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 86357988 Common - hypothetical protein RHE_CH02373 74 COG3791 COG3791, Uncharacterized conserved protein Function unknown 86356432 Nonpathogen - hypothetical protein RHE_CH00783 1 None None None 86356286 Common - putative glycosyltransferase protein RHE_CH00635 34 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 86355707 Common alkB alkylated DNA repair protein RHE_CH00039 58 COG3145 AlkB, Alkylated DNA repair protein DNA replication, recombination, and repair 86357007 Common - hypothetical protein RHE_CH01369 20 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 86357175 Common - hypothetical protein RHE_CH01537 12 None None None 86357168 Common - hypothetical protein RHE_CH01530 29 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 86359497 Common dcp peptidyl-dipeptidase Dcp protein RHE_CH03916 123 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 86359538 Common tyrA chorismate mutase RHE_CH03958 59 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 86355675 Common secB preprotein translocase subunit SecB RHE_CH00006 107 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 86356306 Common flgF flagellar basal body rod protein FlgF RHE_CH00655 125 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 86357137 Common parC DNA topoisomerase IV subunit A RHE_CH01499 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 86357340 Common - probable 2-dehydropantoate 2-reductase (ketopantoate reductase) protein RHE_CH01710 108 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 86357039 Common - putative mechanosensitive ion channel protein RHE_CH01401 207 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 86356045 Common mutS DNA mismatch repair protein RHE_CH00388 198 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 86359155 Common - hypothetical protein RHE_CH03564 2 None None None 86358718 Common - probable oxidoreductase protein RHE_CH03117 58 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 86357297 Common rpoB DNA-directed RNA polymerase subunit beta RHE_CH01667 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 86358226 Common - putative metal-dependent hydrolase protein RHE_CH02619 16 COG4286 COG4286, Uncharacterized conserved protein related to MYG1 family Function unknown 86359481 Common - hypothetical protein RHE_CH03900 94 COG2947 COG2947, Uncharacterized conserved protein Function unknown 86356743 Common - hypothetical protein RHE_CH01100 6 None None None 86358511 Common - probable spermidine/putrescine ABC transporter, substrate-binding protein RHE_CH02908 25 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 86357601 Common - probable 2-methylcitrate dehydratase protein RHE_CH01981 59 COG2079 PrpD, Uncharacterized protein involved in propionate catabolism General function prediction only 86355931 Common - hypothetical conserved membrane protein RHE_CH00273 4 COG2246 COG2246, Predicted membrane protein Function unknown 86357208 Common rplM 50S ribosomal protein L13 RHE_CH01571 234 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 86357776 Common - hypothetical conserved membrane protein RHE_CH02158 80 COG0730 COG0730, Predicted permeases General function prediction only 86359216 Common - hypothetical protein RHE_CH03626 47 COG2319 COG2319, FOG: WD40 repeat General function prediction only 86359137 Common - hypothetical protein RHE_CH03546 38 COG3750 COG3750, Uncharacterized protein conserved in bacteria Function unknown 86357247 Common nuoI NADH dehydrogenase subunit I RHE_CH01613 194 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 86356610 Common - hypothetical protein RHE_CH00964 31 COG4307 COG4307, Uncharacterized protein conserved in bacteria Function unknown 86358748 Nonpathogen - hypothetical protein RHE_CH03147 1 None None None 86356044 Common glnD PII uridylyl-transferase RHE_CH00387 127 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 86357827 Common - probable serine-type D-Ala-D-Ala carboxypeptidase protein RHE_CH02211 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 86357126 Common purM phosphoribosylaminoimidazole synthetase RHE_CH01488 229 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 86356027 Common metK S-adenosylmethionine synthetase RHE_CH00370 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 86356077 Common - hypothetical protein RHE_CH00420 9 None None None 86357934 Common - probable acetyltransferase protein RHE_CH02319 39 COG0456 RimI, Acetyltransferases General function prediction only 162329637 Common acpXL acyl carrier protein RHE_CH02478 101 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 86355692 Common folC bifunctional folylpolyglutamate synthase/dihydrofolate syntase RHE_CH00024 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 86359206 Common - putative sensory box/GGDEF family protein RHE_CH03616 177 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 86355950 Common - putative phosphatidylethanolamine-binding protein RHE_CH00293 125 COG1881 COG1881, Phospholipid-binding protein General function prediction only 86356019 Common - probable lactoylglutathione lyase protein RHE_CH00362 30 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 86356841 Common - putative ubiquinone/menaquinone biosynthesis methyltransferase protein RHE_CH01201 184 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 86359149 Common - hypothetical protein RHE_CH03558 48 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 86358328 Common afuC2 iron(III) ABC transporter, ATP-binding protein RHE_CH02723 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 86358726 Common xdhB xanthine dehydrogenase protein RHE_CH03125 111 COG4631 XdhB, Xanthine dehydrogenase, molybdopterin-binding subunit B Nucleotide transport and metabolism 86359175 Common - probable iron ABC transporter, substrate-binding protein RHE_CH03585 33 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 86356372 Nonpathogen - hypothetical protein RHE_CH00721 9 COG5490 COG5490, Uncharacterized conserved protein Function unknown 86356938 Common pepN aminopeptidase N protein RHE_CH01298 159 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 86356345 Common folDch methylenetetrahydrofolate dehydrogenase/cyclohydrolase protein RHE_CH00694 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 86356210 Common acd1 acyl-CoA dehydrogenase protein RHE_CH00557 155 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 86359580 Common - probable transcriptional regulator protein, LuxR family RHE_CH04001 54 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 86356918 Common gstA glutathione S-transferase protein RHE_CH01278 112 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 86357277 Common aidB acyl-CoA dehydrogenase protein RHE_CH01643 144 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 86356172 Common hslO Hsp33-like chaperonin RHE_CH00518 128 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 86357355 Common - probable sugar ABC transporter, permease protein RHE_CH01725 161 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 86356814 Common - probable organic hydroperoxide resistance (osmotically inducible) protein RHE_CH01174 94 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 86355783 Common recR recombination protein RecR RHE_CH00123 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 86355964 Common - putative nucleoside-diphosphate-sugar epimerase protein RHE_CH00307 106 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 86356269 Common - putative DNA helicase protein RHE_CH00618 63 COG1273 COG1273, Uncharacterized conserved protein Function unknown 86358951 Common - probable transcriptional regulator protein, LysR family RHE_CH03353 173 COG0583 LysR, Transcriptional regulator Transcription 86356711 Common - hypothetical protein RHE_CH01068 137 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 86355722 Common - hypothetical protein RHE_CH00054 30 COG5321 COG5321, Uncharacterized protein conserved in bacteria Function unknown 86359264 Common - CysZ-like protein RHE_CH03674 26 COG2981 CysZ, Uncharacterized protein involved in cysteine biosynthesis Amino acid transport and metabolism 86357631 Common - putative insertion sequence transposase protein RHE_CH02011 52 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 86358016 Common rbsAch3 ribose ABC transporter, ATP-binding protein RHE_CH02401 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 86356406 Common - probable glycosyltransferase protein RHE_CH00757 52 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 86358914 Common - probable urea or short-chain amide ABC transporter, permease protein RHE_CH03315 155 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 86356197 Common - probable methyltransferase protein RHE_CH00544 31 COG4976 COG4976, Predicted methyltransferase (contains TPR repeat) General function prediction only 86357389 Common ilvA threonine dehydratase RHE_CH01759 213 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 86359653 Common - hypothetical protein RHE_CH04075 200 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 86356563 Common - probable deacetylase protein RHE_CH00917 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 86357699 Common qor quinone oxidoreductase protein RHE_CH02080 202 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 86356463 Common - putative hydrolase, haloacid dehalogenase-like family protein RHE_CH00817 30 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 86357336 Common - hypothetical protein RHE_CH01706 33 COG3339 COG3339, Uncharacterized conserved protein Function unknown 86359120 Common - probable transcriptional regulator protein RHE_CH03529 68 COG0640 ArsR, Predicted transcriptional regulators Transcription 86356188 Common - hypothetical protein RHE_CH00535 7 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 86355697 Common - hypothetical protein RHE_CH00029 193 COG3178 COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases General function prediction only 86355823 Common phnK phosphonates transport ATP-binding protein RHE_CH00163 249 COG4107 PhnK, ABC-type phosphonate transport system, ATPase component Inorganic ion transport and metabolism 86356136 Common manB1 beta-mannosidase protein RHE_CH00480 40 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 86356260 Common appA oligopeptide ABC transporter, substrate-binding protein RHE_CH00609 200 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 86357709 Common glmU UDP-N-acetylglucosamine pyrophosphorylase protein RHE_CH02090 237 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 86356893 Common - putative peptidoglycan-binding protein (cell wall degradation activity) RHE_CH01253 12 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 86357382 Common - putative phosphohistidine phosphatase protein RHE_CH01752 73 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 86359691 Common - hypothetical protein RHE_CH04113 41 COG3820 COG3820, Uncharacterized protein conserved in bacteria Function unknown 86357702 Common - probable sugar ABC transporter, permease protein RHE_CH02083 106 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 86357221 Common - putative sensory box/GGDEF family protein RHE_CH01584 177 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 86358375 Common recD exodeoxyribonuclease V alpha subunit protein RHE_CH02771 100 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 86355850 Common cdd cytidine deaminase RHE_CH00191 118 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 86357818 Common hisI phosphoribosyl-AMP cyclohydrolase RHE_CH02202 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 86358502 Common - putative N-acetylglucosamine kinase protein RHE_CH02899 62 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 86359671 Common leuB 3-isopropylmalate dehydrogenase RHE_CH04093 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 86358488 Common - probable aldehyde dehydrogenase protein RHE_CH02885 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 86356215 Common - hypothetical protein RHE_CH00562 51 COG3791 COG3791, Uncharacterized conserved protein Function unknown 86357850 Common gph1 phosphoglycolate phosphatase protein RHE_CH02235 144 COG0546 Gph, Predicted phosphatases General function prediction only 86355753 Common gabDch succinate-semialdehyde dehydrogenase protein RHE_CH00092 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 86356777 Nonpathogen - hypothetical protein RHE_CH01135 7 None None None 86355713 Common hisH imidazole glycerol phosphate synthase subunit HisH RHE_CH00045 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 86357692 Common - hypothetical protein RHE_CH02073 62 COG3791 COG3791, Uncharacterized conserved protein Function unknown 86358605 Common - hypothetical protein RHE_CH03003 14 None None None 86358048 Common - putative inosine-5`-monophosphate dehydrogenase protein RHE_CH02435 132 COG0517 COG0517, FOG: CBS domain General function prediction only 86358289 Common - probable ferrichrome ABC transporter, substrate-binding protein RHE_CH02683 116 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 86355945 Common - putative oxidoreductase protein RHE_CH00288 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 86359019 Common - putative integral membrane prenyltransferase protein RHE_CH03427 62 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 86356791 Common - putative transporter, permease protein RHE_CH01149 31 COG4587 COG4587, ABC-type uncharacterized transport system, permease component General function prediction only 86356968 Common - hypothetical protein RHE_CH01328 14 COG4731 COG4731, Uncharacterized protein conserved in bacteria Function unknown 86358086 Common - probable alcohol dehydrogenase protein RHE_CH02474 209 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 86356453 Common - probable transcriptional regulator protein, LysR family RHE_CH00807 123 COG0583 LysR, Transcriptional regulator Transcription 86358065 Common xynA beta-xylosidase protein RHE_CH02453 39 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 86358135 Common - probable transcriptional regulator protein, AraC family RHE_CH02525 149 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 86358997 Nonpathogen - hypothetical protein RHE_CH03405 2 None None None 86357527 Common clpS ATP-dependent Clp protease adaptor protein ClpS RHE_CH01906 119 COG2127 COG2127, Uncharacterized conserved protein Function unknown 86359527 Common ccmB heme ABC transporter, permease protein (involved in cytochrome-c biogenesis) RHE_CH03947 82 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 86357640 Common - hypothetical protein RHE_CH02021 92 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 86356882 Common - hypothetical protein RHE_CH01242 53 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 86358413 Common ompA outer membrane lipoprotein RHE_CH02810 169 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 86358801 Nonpathogen - hypothetical protein RHE_CH03201 1 None None None 86356107 Common - probable D-amino acid dehydrogenase protein RHE_CH00451 125 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 86359643 Common - putative acetyltransferase protein RHE_CH04065 77 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 86359018 Common - hypothetical protein RHE_CH03426 11 None None None 86357157 Common - putative carbamoyl-phosphate-synthetase protein RHE_CH01519 120 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 86357859 Common lysM cell-wall lytic enzyme RHE_CH02244 47 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 86359698 Common parA2 chromosome partitioning protein A RHE_CH04120 210 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 86358259 Nonpathogen - hypothetical protein RHE_CH02653 1 None None None 86357649 Nonpathogen - hypothetical protein RHE_CH02030 3 None None None 86359385 Common ftsE cell-division ATP-binding protein RHE_CH03802 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 86358835 Common pssT2 endo-1,4-beta-xylanase (exopolysaccharide export) protein RHE_CH03236 15 None None None 86358917 Common - putative phosphatase protein RHE_CH03318 54 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 86356656 Common - putative NTP pyrophosphohydrolase protein, MutT/nudix family RHE_CH01010 35 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 86357472 Common - hypothetical protein RHE_CH01845 3 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 86359665 Common - hypothetical protein RHE_CH04087 21 COG5515 COG5515, Uncharacterized conserved small protein Function unknown 86358798 Common - probable glycosyltransferase protein RHE_CH03198 213 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 86357380 Common - hypothetical protein RHE_CH01750 7 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 86358989 Common - probable glycosyltransferase protein RHE_CH03391 15 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 86359038 Common - probable branched-chain amino acid ABC transporter, permease protein RHE_CH03446 99 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 162329643 Common fabH 3-oxoacyl-(acyl carrier protein) synthase III RHE_CH01532 204 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 86357288 Common - probable tRNA/rRNA methyltransferase protein RHE_CH01655 213 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 86358424 Common pncA pyrazinamidase/nicotinamidase protein RHE_CH02821 107 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 86357962 Common - putative ABC transporter protein RHE_CH02347 118 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 86356507 Common kupch1 potassium transporter protein RHE_CH00861 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 86357627 Common - hypothetical protein RHE_CH02007 3 None None None 86357916 Common - putative amino acid ABC transporter, substrate-binding protein RHE_CH02301 14 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 86357270 Common - hypothetical protein RHE_CH01636 28 COG5349 COG5349, Uncharacterized protein conserved in bacteria Function unknown 86356050 Common spoU rRNA methylase protein, TrmH family RHE_CH00393 212 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 86356755 Common - putative lysozyme protein RHE_CH01113 40 COG3772 COG3772, Phage-related lysozyme (muraminidase) General function prediction only 86359258 Common - probable transcriptional regulator protein, LacI family RHE_CH03668 63 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 86356388 Common dppDch1 dipeptide ABC transporter, ATP-binding protein RHE_CH00739 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 86357824 Common pipch2 proline iminopeptidase protein RHE_CH02208 103 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 86355844 Common - hypothetical protein RHE_CH00184 46 COG3545 COG3545, Predicted esterase of the alpha/beta hydrolase fold General function prediction only 86356324 Common - hypothetical protein RHE_CH00673 4 None None None 86359056 Common tolR protein transporter protein RHE_CH03465 129 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 86356845 Common - putative transcriptional regulator-repressor protein RHE_CH01205 97 COG2378 COG2378, Predicted transcriptional regulator Transcription 86358211 Common - probable ring-cleaving dioxygenase protein RHE_CH02604 35 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 86356011 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase RHE_CH00354 196 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 86357077 Common rpsR 30S ribosomal protein S18 RHE_CH01439 215 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 86357696 Common - probable transcriptional regulator protein, GntR family RHE_CH02077 85 COG1802 GntR, Transcriptional regulators Transcription 86358532 Nonpathogen - hypothetical protein RHE_CH02930 1 None None None 86356158 Nonpathogen - hypothetical protein RHE_CH00503 1 None None None 86357108 Common - hypothetical protein RHE_CH01470 36 COG2318 DinB, Uncharacterized protein conserved in bacteria Function unknown 86359034 Common - putative phosphoketolase RHE_CH03442 65 COG3957 COG3957, Phosphoketolase Carbohydrate transport and metabolism 86357488 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B RHE_CH01862 214 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 86359426 Common - putative sugar ABC transporter, substrate-binding protein RHE_CH03844 115 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86356486 Common kefB glutathione-regulated potassium-efflux transporter protein RHE_CH00840 208 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 86356873 Common - probable universal stress protein RHE_CH01233 59 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 86359065 Common - hypothetical protein RHE_CH03474 29 COG3871 COG3871, Uncharacterized stress protein (general stress protein 26) General function prediction only 86359028 Nonpathogen - hypothetical protein RHE_CH03436 2 None None None 86357117 Common uvrC excinuclease ABC subunit C RHE_CH01479 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 86357353 Common - probable sugar ABC transporter, substrate-binding protein RHE_CH01723 52 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86358755 Common - probable transporter, permease protein RHE_CH03154 97 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86355895 Common - probable restriction system protein RHE_CH00236 26 COG1715 Mrr, Restriction endonuclease Defense mechanisms 86356451 Common - probable phosphate transport permease protein RHE_CH00805 162 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 86357144 Common - probable transcriptional regulator protein, MarR family RHE_CH01506 22 COG1846 MarR, Transcriptional regulators Transcription 86358467 Common - probable transglycosylase protein RHE_CH02864 40 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 86356182 Common - short chain dehydrogenase RHE_CH00529 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 86356682 Nonpathogen - hypothetical protein RHE_CH01038 2 None None None 86359170 Common - hypothetical protein RHE_CH03580 7 None None None 86357372 Common phhA phenylalanine 4-monooxygenase RHE_CH01742 45 COG3186 COG3186, Phenylalanine-4-hydroxylase Amino acid transport and metabolism 86358660 Common - probable insertion sequence transposase protein RHE_CH03058 19 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 86358814 Common pssM ketal pyruvate transferase protein RHE_CH03215 12 None None None 86356923 Common - hypothetical protein RHE_CH01283 15 None None None 86358178 Common - tRNA-dihydrouridine synthase A RHE_CH02569 207 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 86359218 Common - putative acetyltransferase protein RHE_CH03628 80 COG3153 COG3153, Predicted acetyltransferase General function prediction only 86357037 Nonpathogen - hypothetical protein RHE_CH01399 1 None None None 86356553 Common - hypothetical protein RHE_CH00907 103 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 86356650 Common - hypothetical protein RHE_CH01004 5 None None None 86359660 Common - hypothetical protein RHE_CH04082 7 None None None 86356975 Common - hypothetical protein RHE_CH01335 21 COG5622 COG5622, Protein required for attachment to host cells Cell motility and secretion 86357286 Nonpathogen - hypothetical protein RHE_CH01653 1 None None None 86355800 Common moeB molybdopterin biosynthesis protein MoeB RHE_CH00140 222 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 86358938 Common - hypothetical protein RHE_CH03340 7 None None None 86355995 Common - putative carboxypeptidase-related protein RHE_CH00338 37 COG2939 COG2939, Carboxypeptidase C (cathepsin A) Amino acid transport and metabolism 86357536 Common pyrH uridylate kinase RHE_CH01915 231 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 86356636 Nonpathogen - hypothetical protein RHE_CH00990 2 None None None 86358162 Common - hypothetical protein RHE_CH02553 45 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 86356320 Common flaCch1 flagellin C protein RHE_CH00669 95 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 86358518 Common cinRch autoinducer transcriptional regulator protein RHE_CH02915 46 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 86358105 Common - probable adenylate cyclase protein RHE_CH02493 78 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 86356767 Common - probable transcriptional regulator protein, LysR family RHE_CH01125 134 COG0583 LysR, Transcriptional regulator Transcription 86358833 Nonpathogen pssO exopolysaccharide inner membrane protein RHE_CH03234 2 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 86356837 Common - probable transcriptional regulator protein, TetR family RHE_CH01197 83 COG1309 AcrR, Transcriptional regulator Transcription 86355988 Common prfC peptide chain release factor 3 protein RHE_CH00331 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 86356716 Common - hypothetical protein RHE_CH01073 66 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 86359135 Common - putative N-formylglutamate amidohydrolase protein RHE_CH03544 41 COG3931 COG3931, Predicted N-formylglutamate amidohydrolase Amino acid transport and metabolism 86357864 Common - putative selenocysteine lyase protein RHE_CH02249 240 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 86358394 Common ilvI acetolactate synthase 3 catalytic subunit RHE_CH02790 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 86358849 Common - hypothetical protein RHE_CH03250 140 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 86355767 Common fabA 3-hydroxydecanoyl-(acyl carrier protein) dehydratase RHE_CH00107 82 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 86359591 Common mtgA monofunctional biosynthetic peptidoglycan transglycosylase RHE_CH04012 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 86356093 Common engB GTPase EngB RHE_CH00436 175 COG0218 COG0218, Predicted GTPase General function prediction only 86356709 Common fusA1 elongation factor G RHE_CH01066 235 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 86358941 Common - hypothetical protein RHE_CH03343 14 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 86356567 Common matB malonyl-CoA synthase RHE_CH00921 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 86357153 Common - probable dTDP-rhamnose-3,5-epimerase protein RHE_CH01515 166 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 86356475 Common groES co-chaperonin GroES RHE_CH00829 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 86357042 Common - putative aminomethyltransferase protein (glycine cleavage) RHE_CH01404 128 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 86359300 Common - putative transcriptional regulator protein, LacI family RHE_CH03710 125 COG1609 PurR, Transcriptional regulators Transcription 86358651 Common papS poly(A) polymerase protein RHE_CH03049 198 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 86359150 Common kpsF polysialic acid capsule expression protein RHE_CH03559 145 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 86356250 Common - probable arsenical pump membrane protein RHE_CH00599 118 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 86358171 Nonpathogen - hypothetical protein RHE_CH02562 1 None None None 86357022 Common rpoZ DNA-directed RNA polymerase subunit omega RHE_CH01384 113 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 86356827 Common tlyC hemolysin protein RHE_CH01187 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 86358684 Nonpathogen - hypothetical protein RHE_CH03083 4 None None None 86358363 Common adh alcohol dehydrogenase (NADP+) protein RHE_CH02758 196 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 86358921 Common braG amino acid ABC transporter, ATP-binding protein RHE_CH03323 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 86356259 Common appB oligopeptide ABC transporter, permease protein RHE_CH00608 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 86357889 Common - hypothetical conserved membrane protein RHE_CH02274 27 COG5478 COG5478, Predicted small integral membrane protein Function unknown 86358976 Common - probable sugar kinase protein RHE_CH03378 97 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 86359195 Common cyaD adenylate cyclase protein RHE_CH03605 88 COG4252 COG4252, Predicted transmembrane sensor domain Signal transduction mechanisms 86358197 Common - hypothetical protein RHE_CH02590 22 COG3791 COG3791, Uncharacterized conserved protein Function unknown 86358182 Common - hypothetical protein RHE_CH02573 6 None None None 86356830 Common ilvE1 aminotransferase RHE_CH01190 197 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 86357056 Common - hypothetical protein RHE_CH01418 95 COG2962 RarD, Predicted permeases General function prediction only 86358260 Nonpathogen - hypothetical protein RHE_CH02654 2 None None None 86357031 Common - putative two-component response regulator protein RHE_CH01393 22 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 86357590 Common - probable conjugal transfer protein RHE_CH01970 34 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 86358380 Common - putative mechanosensitive ion channel protein RHE_CH02776 198 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 86357349 Common - probable transcriptional regulator protein, LacI family RHE_CH01719 128 COG1609 PurR, Transcriptional regulators Transcription 86356646 Common smc chromosome partition protein RHE_CH01000 175 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 86358028 Common - putative cytochrome biogenesis protein RHE_CH02415 77 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 86358786 Nonpathogen - hypothetical protein RHE_CH03186 10 COG4274 COG4274, Uncharacterized conserved protein Function unknown 86356705 Common - putative alkyl sulfatase beta-lactamase family protein RHE_CH01062 82 COG2015 COG2015, Alkyl sulfatase and related hydrolases Secondary metabolites biosynthesis, transport, and catabolism 86356193 Common pyrD dihydroorotate dehydrogenase 2 RHE_CH00540 230 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 86358861 Common - hypothetical protein RHE_CH03262 37 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 86356053 Common - hypothetical protein RHE_CH00396 33 COG3427 COG3427, Uncharacterized conserved protein Function unknown 86356151 Common - probable altronate hydrolase protein RHE_CH00495 73 COG2721 UxaA, Altronate dehydratase Carbohydrate transport and metabolism 86358268 Common - hypothetical protein RHE_CH02662 20 COG5552 COG5552, Uncharacterized conserved protein Function unknown 86359211 Common - probable 2-hydroxyacid dehydrogenase protein RHE_CH03621 228 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 86359477 Common sdhD succinate dehydrogenase subunit D, membrane anchor protein RHE_CH03896 40 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 86356424 Common - probable insertion sequence transposase protein RHE_CH00775 19 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 86359474 Common omp4 outer membrane lipoprotein RHE_CH03893 7 None None None 86359075 Common - hypothetical protein RHE_CH03484 34 COG2318 DinB, Uncharacterized protein conserved in bacteria Function unknown 86358853 Common - hypothetical protein RHE_CH03254 11 None None None 86357901 Common purL phosphoribosylformylglycinamidine synthase II RHE_CH02286 234 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 86357197 Common - probable glycosyltransferase protein RHE_CH01560 186 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 86355986 Common - putative acetyltransferase protein RHE_CH00329 4 COG4552 Eis, Predicted acetyltransferase involved in intracellular survival and related acetyltransferases General function prediction only 86357567 Common nifR probable tRNA-dihydrouridine synthase protein RHE_CH01946 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 86358389 Common - putative oxidoreductase protein RHE_CH02785 45 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 86358667 Common rpoE3 RNA polymerase sigma factor protein (sigma-24) RHE_CH03065 85 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 86358208 Common - hypothetical protein RHE_CH02601 5 None None None 86357366 Common - probable ubiquinone/menaquinone biosynthesis methyltransferase protein RHE_CH01736 165 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 86359307 Common nrdI ribonucleotide reductase stimulatory protein RHE_CH03717 37 COG1780 NrdI, Protein involved in ribonucleotide reduction Nucleotide transport and metabolism 86357833 Common - probable transcriptional regulator protein, MerR family RHE_CH02217 51 COG0789 SoxR, Predicted transcriptional regulators Transcription 86358931 Common - hypothetical protein RHE_CH03333 13 None None None 86359625 Common - hypothetical protein RHE_CH04046 7 None None None 86358904 Common ureC urease subunit alpha RHE_CH03305 97 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 86359082 Common - hypothetical protein RHE_CH03491 4 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 86356786 Common - putative L-asparaginase II protein RHE_CH01144 46 COG4448 AnsA, L-asparaginase II Amino acid transport and metabolism 86357444 Common - hypothetical protein RHE_CH01816 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 86356803 Common - putative exonuclease protein involved in mRNA processing RHE_CH01163 86 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 86359053 Common tolB translocation protein TolB RHE_CH03462 150 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 86356991 Common - putative glycosyltransferase protein RHE_CH01353 146 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 86357984 Common aroG phospho-2-dehydro-3-heoxyheptonate aldolase RHE_CH02369 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 86358825 Common pssE glucuronosyltransferase protein RHE_CH03226 16 COG5017 COG5017, Uncharacterized conserved protein Function unknown 86358968 Common ugpEch2 sn-glycerol-3-phosphate ABC transporter, permease protein RHE_CH03370 143 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 86359598 Common phbB acetoacetyl-CoA reductase protein RHE_CH04019 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 86356246 Common - hypothetical protein RHE_CH00595 62 COG3220 COG3220, Uncharacterized protein conserved in bacteria Function unknown 86355917 Common - putative hydrolase protein RHE_CH00259 47 COG1647 COG1647, Esterase/lipase General function prediction only 86357908 Common - probable amino acid ABC transporter, substrate-binding protein RHE_CH02293 156 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 86358948 Common - putative esterase protein RHE_CH03350 87 COG0657 Aes, Esterase/lipase Lipid metabolism 86358649 Common - hypothetical protein RHE_CH03047 2 None None None 86356520 Common - hypothetical protein RHE_CH00874 144 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 86355725 Common helO helicase protein RHE_CH00057 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 86359278 Common - putative multidrug efflux transporter protein RHE_CH03688 167 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 86355962 Common sun tRNA and rRNA cytosine-C5-methylase (RNA methyltransferase) protein RHE_CH00305 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 86358112 Common - chromosome replication initiation inhibitor protein RHE_CH02500 97 COG0583 LysR, Transcriptional regulator Transcription 86358612 Common - probable two-component response regulator protein RHE_CH03010 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 86358588 Common - probable sugar ABC transporter, ATP-binding protein RHE_CH02986 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 86359456 Common priA primosome assembly protein PriA RHE_CH03875 213 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 86357002 Common - probable oxidoreductase protein RHE_CH01364 189 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 86357438 Common - hypothetical protein RHE_CH01810 11 COG3827 COG3827, Uncharacterized protein conserved in bacteria Function unknown 86358898 Common - probable acriflavin resistance protein (transporter protein) RHE_CH03299 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 86357951 Common folP dihydropteroate synthase protein RHE_CH02336 217 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 86357244 Common - hypothetical protein RHE_CH01610 25 COG3743 COG3743, Uncharacterized conserved protein Function unknown 86358433 Common mcpW methyl-accepting chemotaxis protein RHE_CH02830 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 86356608 Common thrB homoserine kinase RHE_CH00962 68 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 86357009 Nonpathogen - hypothetical protein RHE_CH01371 1 None None None 86357654 Common - probable transcriptional regulator protein, MarR family RHE_CH02035 29 COG1846 MarR, Transcriptional regulators Transcription 86355990 Common - putative acetyltransferase protein RHE_CH00333 47 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 86357518 Common aapQ general L-amino acid ABC transporter, permease protein RHE_CH01897 173 COG4597 BatB, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 86357586 Nonpathogen - hypothetical protein RHE_CH01966 1 None None None 86357496 Common accBch acetyl-CoA carboxylase biotin carboxyl carrier protein subunit RHE_CH01870 191 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 86358123 Nonpathogen - putative cytochrome c-like protein RHE_CH02511 3 COG3909 COG3909, Cytochrome c556 Energy production and conversion 86357418 Common rbsAch2 ribose ABC transporter, ATP-binding protein RHE_CH01788 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 86358954 Common - probable multidrug resistance protein RHE_CH03356 228 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86357734 Common ppiB peptidyl prolyl cis-trans isomerase B signal peptide protein RHE_CH02115 198 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 86358870 Common hmuV hemin transport system, ATP-binding protein RHE_CH03271 249 COG4559 COG4559, ABC-type hemin transport system, ATPase component Inorganic ion transport and metabolism 86359405 Common dnaJ3 molecular chaperone protein, DnaJ family RHE_CH03822 140 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 86356693 Common cyaFch1 adenylate cyclase protein RHE_CH01049 67 COG5616 COG5616, Predicted integral membrane protein Function unknown 86356534 Common mcpV2 methyl-accepting chemotaxis protein RHE_CH00888 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 86357328 Common rpsK 30S ribosomal protein S11 RHE_CH01698 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 86359547 Common - hypothetical protein RHE_CH03967 41 COG3786 COG3786, Uncharacterized protein conserved in bacteria Function unknown 86358594 Common - hypothetical protein RHE_CH02992 7 None None None 86358233 Common ftsZ1 cell division protein FtsZ RHE_CH02626 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 86356331 Common flgK flagellar hook-associated protein FlgK RHE_CH00680 77 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 86358244 Common - hypothetical protein RHE_CH02637 61 COG3791 COG3791, Uncharacterized conserved protein Function unknown 86359509 Common - putative ABC transporter, substrate-binding protein RHE_CH03929 56 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 86356416 Nonpathogen - hypothetical protein RHE_CH00767 4 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 86357755 Common - probable adenylate cyclase (possibly two-component response regulator) protein RHE_CH02136 60 COG5616 COG5616, Predicted integral membrane protein Function unknown 86359005 Common nodTch nodulation protein (outer membrane efflux protein) RHE_CH03413 113 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 86357878 Common - hypothetical protein RHE_CH02263 48 COG2833 COG2833, Uncharacterized protein conserved in bacteria Function unknown 86358495 Common - probable ABC transporter, permease protein RHE_CH02892 185 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 86357449 Common - hypothetical protein RHE_CH01821 135 COG1354 COG1354, Uncharacterized conserved protein Function unknown 86358699 Common oppC oligopeptide ABC transporter, permease protein RHE_CH03098 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 86358477 Common - probable enterobacter ribonuclease protein RHE_CH02874 42 COG3719 Rna, Ribonuclease I Translation, ribosomal structure and biogenesis 86355910 Common - putative hydrolase protein, haloacid dehalogenase-like family RHE_CH00252 18 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 86359089 Common - potassium/proton antiporter RHE_CH03498 127 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 86359116 Common - putative chemotaxis sensory transducer protein RHE_CH03525 105 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 86357231 Common - hypothetical protein RHE_CH01594 67 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 86358352 Common rtlK L-ribulokinase protein RHE_CH02747 176 COG1069 AraB, Ribulose kinase Energy production and conversion 86355854 Common - hypothetical protein RHE_CH00195 51 COG3577 COG3577, Predicted aspartyl protease General function prediction only 86358313 Common - hypothetical protein RHE_CH02707 23 COG3672 COG3672, Predicted periplasmic protein Function unknown 86355773 Common - putative hydrolase protein RHE_CH00113 175 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 86356491 Common - probable phosphoglycolate phosphatase protein RHE_CH00845 64 COG0546 Gph, Predicted phosphatases General function prediction only 86359552 Common ftsK2 cell division protein RHE_CH03972 197 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 86356409 Common - probable nucleoside-diphosphate-sugar epimerase protein RHE_CH00760 228 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 86358692 Common - putative phosphohydrolase protein RHE_CH03091 123 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 86357000 Common - probable two-component response regulator protein RHE_CH01362 150 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 86359142 Common - hypothetical protein RHE_CH03551 50 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 86358482 Common - putative translation initiation inhibitor protein RHE_CH02879 94 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 86356143 Common - probable transcriptional regulator protein, LysR family RHE_CH00487 165 COG0583 LysR, Transcriptional regulator Transcription 86356988 Common noeL2 GDP-mannose 4,6-dehydratase protein RHE_CH01350 213 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 86358727 Common xdhC xanthine dehydrogenase protein RHE_CH03126 66 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 86358860 Common - putative bleomycin resistance protein RHE_CH03261 12 None None None 86359641 Common rpmA 50S ribosomal protein L27 RHE_CH04063 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 86358258 Nonpathogen - hypothetical protein RHE_CH02652 2 None None None 86355736 Common - hypothetical protein RHE_CH00075 19 COG4289 COG4289, Uncharacterized protein conserved in bacteria Function unknown 86357064 Common - probable glycosyl hydrolase, lysozyme protein RHE_CH01426 41 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 86357664 Common - probable nitrate/sulfonate/bicarbonate ABC transporter, ATP-binding protein RHE_CH02045 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 86357670 Common - probable oxidoreductase protein RHE_CH02051 129 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 86359317 Common - putative 3-oxoacyl-[acyl-carrier protein] reductase protein RHE_CH03727 234 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 86358142 Common - putative protein-tyrosine-phosphatase protein RHE_CH02532 111 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 86356223 Common - putative sensory box/GGDEF family protein RHE_CH00570 177 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 86357947 Common - hypothetical protein RHE_CH02332 43 COG3768 COG3768, Predicted membrane protein Function unknown 86355886 Common - hypothetical protein RHE_CH00227 5 None None None 86359236 Common - probable sugar ABC transporter, ATP-binding protein RHE_CH03646 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 86358779 Nonpathogen - hypothetical protein RHE_CH03179 1 None None None 86357770 Nonpathogen - hypothetical protein RHE_CH02152 1 None None None 86358554 Common kbl 2-amino-3-ketobutyrate coenzyme A ligase RHE_CH02952 190 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 86357871 Common - putative acetyltransferase protein RHE_CH02256 78 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 86357469 Common tig trigger factor RHE_CH01842 216 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 86356668 Common tetA tetracycline efflux transporter protein RHE_CH01023 220 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86356099 Nonpathogen - hypothetical protein RHE_CH00443 1 None None None 86357713 Common - hypothetical protein RHE_CH02094 38 COG2938 COG2938, Uncharacterized conserved protein Function unknown 86356731 Common - hypothetical protein RHE_CH01088 26 COG3753 COG3753, Uncharacterized protein conserved in bacteria Function unknown 86356747 Nonpathogen - hypothetical protein RHE_CH01105 1 None None None 86359686 Common - hypothetical protein RHE_CH04108 44 COG5360 COG5360, Uncharacterized protein conserved in bacteria Function unknown 86357570 Common - hypothetical protein RHE_CH01949 33 COG3806 ChrR, Transcriptional activator Transcription 86357677 Common uxuAch mannonate dehydratase protein RHE_CH02058 58 COG1312 UxuA, D-mannonate dehydratase Carbohydrate transport and metabolism 86356377 Nonpathogen - hypothetical protein RHE_CH00727 9 None None None 86357462 Common crtB phytoene synthase protein RHE_CH01834 43 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 86358507 Common - putative flavin reductase protein RHE_CH02904 91 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 86358201 Common - probable ornithine cyclodeaminase protein RHE_CH02594 83 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 86358640 Common fbcF ubiquinol-cytochrome-c reductase, iron-sulfur subunit protein RHE_CH03038 109 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 86359635 Common sfuA iron(III) ABC transporter, substrate-binding protein RHE_CH04056 126 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 86357317 Common rplE 50S ribosomal protein L5 RHE_CH01687 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 86359159 Common - probable threonine aldolase protein RHE_CH03568 99 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 86355922 Common pheT phenylalanyl-tRNA synthetase subunit beta RHE_CH00264 229 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 86358500 Common - probable sugar ABC transporter, permease protein RHE_CH02897 180 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 86356659 Common - probable beta-lactamase family protein RHE_CH01013 134 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 86359689 Common - hypothetical protein RHE_CH04111 8 COG5508 COG5508, Uncharacterized conserved small protein Function unknown 86358720 Common - hypothetical protein RHE_CH03119 56 COG3832 COG3832, Uncharacterized conserved protein Function unknown 86357431 Nonpathogen - hypothetical protein RHE_CH01801 1 None None None 86356084 Common - probable transcriptional regulator protein, ArsR family RHE_CH00427 95 COG0640 ArsR, Predicted transcriptional regulators Transcription 86358003 Common - putative hydrolase protein RHE_CH02388 37 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 86357611 Nonpathogen - hypothetical protein RHE_CH01991 1 None None None 86356147 Common - probable sugar ABC transporter, ATP-binding protein RHE_CH00491 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 86355977 Common - putative endonuclease protein RHE_CH00320 59 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 86358560 Common - putative sulfite oxidase protein RHE_CH02958 100 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 86357993 Common - probable acylphosphatase protein RHE_CH02378 130 COG1254 AcyP, Acylphosphatases Energy production and conversion 86359296 Common - probable sugar ABC transporter, ATP-binding protein RHE_CH03706 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 86355861 Common pilA component of type IV pilus, pilin subunit protein RHE_CH00202 3 COG3847 Flp, Flp pilus assembly protein, pilin Flp Intracellular trafficking and secretion 86356400 Common - putative acetyltransferase protein RHE_CH00751 63 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 86357422 Common - probable glycosyltransferase protein RHE_CH01792 43 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 86356688 Nonpathogen - hypothetical protein RHE_CH01044 5 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 86356313 Common flgA flagellar basal body P-ring biosynthesis protein FlgA RHE_CH00662 39 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 86357767 Common - putative sensory box/GGDEF family protein RHE_CH02148 177 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 86356277 Common - probable two-component sensor histidine kinase protein RHE_CH00626 219 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 86356529 Common - hypothetical protein RHE_CH00883 131 COG1704 LemA, Uncharacterized conserved protein Function unknown 86358569 Common - putative uracil DNA glycosylase protein RHE_CH02967 161 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 86356115 Common - putative sensory box/GGDEF family protein RHE_CH00459 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 86359319 Common - probable NADH-ubiquinone oxidoreductase chain J protein RHE_CH03729 159 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 86356622 Common - putative sensory box/GGDEF family protein RHE_CH00976 184 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 86357661 Common - putative FAD linked oxidase protein RHE_CH02042 37 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 86355959 Common - hypothetical protein RHE_CH00302 23 COG3489 COG3489, Predicted periplasmic lipoprotein General function prediction only 86356675 Nonpathogen - hypothetical protein RHE_CH01031 1 None None None 86358541 Common - hypothetical protein RHE_CH02939 6 COG5664 COG5664, Predicted secreted Zn-dependent protease Posttranslational modification, protein turnover, chaperones 86356472 Common - hypothetical protein RHE_CH00826 3 None None None 86357772 Common - putative transporter protein, TerC family RHE_CH02154 87 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 86355818 Common - probable phosphonate ABC transporter, permease protein RHE_CH00158 89 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 86356794 Common - hypothetical conserved membrane protein RHE_CH01153 15 COG4244 COG4244, Predicted membrane protein Function unknown 86359532 Common ispZ intracellular septation protein A RHE_CH03952 92 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 86356025 Common - hypothetical protein RHE_CH00368 13 COG5568 COG5568, Uncharacterized small protein Function unknown 86357549 Common lexA LexA repressor RHE_CH01928 165 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 86358056 Common cobS cobalamin synthase RHE_CH02444 87 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 86359512 Common - probable RNA polymerase sigma factor protein (sigma-70), ECF family RHE_CH03932 155 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 86357295 Common rplJ 50S ribosomal protein L10 RHE_CH01665 212 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 86357204 Common argC N-acetyl-gamma-glutamyl-phosphate reductase RHE_CH01567 206 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 86358088 Common - 3-oxoacyl-(acyl carrier protein) synthase II RHE_CH02476 146 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 86358739 Common - hypothetical protein RHE_CH03138 42 COG2268 COG2268, Uncharacterized protein conserved in bacteria Function unknown 86355682 Common - probable oxidoreductase protein RHE_CH00013 34 COG0778 NfnB, Nitroreductase Energy production and conversion 86357135 Common aspS aspartyl-tRNA synthetase RHE_CH01497 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 86358795 Common - probable UDP-glucose 4-epimerase protein RHE_CH03195 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 86358839 Common - probable esterase/lipase/thioesterase protein RHE_CH03240 32 COG0400 COG0400, Predicted esterase General function prediction only 86356957 Common - hypothetical conserved membrane protein RHE_CH01317 9 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 86358732 Common lldD3 L-lactate dehydrogenase (cytochrome) protein RHE_CH03131 114 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 86359041 Common - probable branched-chain amino acid ABC transporter, ATP-binding protein RHE_CH03449 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 86356548 Common - hypothetical protein RHE_CH00902 6 None None None 86356280 Nonpathogen - putative two-component response regulator protein RHE_CH00629 1 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 86357206 Common floR florfenicol/chloramphenicol resistance transporter protein, Bcr/CflA subfamily RHE_CH01569 162 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86355974 Common - hypothetical protein RHE_CH00317 102 COG1801 COG1801, Uncharacterized conserved protein Function unknown 86357557 Common - probable arylesterase protein RHE_CH01936 13 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 86357184 Common - putative 2-deoxyglucose-6-phosphate phosphatase protein RHE_CH01546 65 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 86358761 Common ilvDch2 dihydroxy-acid dehydratase RHE_CH03160 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 86357083 Common fabF1 3-oxoacyl-(acyl carrier protein) synthase II RHE_CH01445 211 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 86359579 Common ndvA beta-1,2-glucan ABC transporter, ATP-binding protein RHE_CH04000 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 86357098 Common - putative monooxygenase protein RHE_CH01460 71 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 86359447 Common - putative nitrate/sulfonate/bicarbonate ABC transporter, substrate-binding protein RHE_CH03866 91 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 86356351 Common aglK alpha-glucoside ABC transporter, ATP-binding protein RHE_CH00700 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 86358880 Common - putative dehydrogenase protein RHE_CH03281 35 None None None 86356311 Common fliE flagellar hook-basal body protein FliE RHE_CH00660 14 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 86357508 Common cspA3 cold shock protein RHE_CH01885 157 COG1278 CspC, Cold shock proteins Transcription 86358299 Common - putative translation initiation inhibitor protein RHE_CH02693 94 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 86358730 Common - hypothetical conserved membrane protein RHE_CH03129 36 COG3748 COG3748, Predicted membrane protein Function unknown 86359091 Common fbaB fructose-bisphosphate aldolase protein RHE_CH03500 32 COG3588 COG3588, Fructose-1,6-bisphosphate aldolase Carbohydrate transport and metabolism 86356442 Common - probable transcriptional regulator protein, LysR family RHE_CH00796 167 COG0583 LysR, Transcriptional regulator Transcription 86359271 Common smoF sorbitol/mannitol ABC transporter, permease protein RHE_CH03681 147 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 86359312 Common - probable transcriptional regulator protein RHE_CH03722 78 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 86356109 Common - hypothetical protein RHE_CH00453 4 COG3070 TfoX, Regulator of competence-specific genes Transcription 86359613 Common galM aldose-1-epimerase protein RHE_CH04034 94 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 86356430 Nonpathogen - hypothetical protein RHE_CH00781 1 None None None 86356609 Common rnhA ribonuclease H RHE_CH00963 180 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 86359371 Common - short chain dehydrogenase RHE_CH03788 234 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 86356677 Common - hypothetical protein RHE_CH01033 6 COG2932 COG2932, Predicted transcriptional regulator Transcription 86358679 Common fhs formate-tetrahydrofolate ligase protein RHE_CH03078 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 86359499 Common - putative amino acid efflux protein, LysE family RHE_CH03918 64 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 86357748 Common - probable two-component sensor histidine kinase protein RHE_CH02129 195 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 86359483 Common gpsA glycerol-3-phosphate dehydrogenase (NAD(P)+) protein RHE_CH03902 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 86359431 Common - hypothetical protein RHE_CH03849 109 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 86356047 Common - hypothetical protein RHE_CH00390 71 COG3176 COG3176, Putative hemolysin General function prediction only 86357272 Common topA DNA topoisomerase I RHE_CH01638 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 86357898 Common - hypothetical protein RHE_CH02283 2 COG5457 COG5457, Uncharacterized conserved small protein Function unknown 86356212 Common fadB2 enoyl-CoA hydratase protein RHE_CH00559 168 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 86358076 Common ddlA D-alanine-D-alanine ligase protein RHE_CH02464 213 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 86358586 Common - probable sugar ABC transporter, permease protein RHE_CH02984 175 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 86357781 Common rapB1 autoaggregation protein (adhering protein) RHE_CH02163 13 None None None 86356037 Common - probable O-sialoglycoprotein endopeptidase protein RHE_CH00380 192 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 86358703 Common kdgK 2-dehydro-3-deoxygluconokinase protein RHE_CH03102 103 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 86359351 Common - putative acetyltransferase protein RHE_CH03767 17 COG0456 RimI, Acetyltransferases General function prediction only 86356908 Nonpathogen - hypothetical protein RHE_CH01268 3 None None None 86358114 Common - putative cation transporter protein RHE_CH02502 84 COG1285 SapB, Uncharacterized membrane protein Function unknown 86356977 Common - hypothetical protein RHE_CH01337 2 None None None 86356527 Common glyQ glycyl-tRNA synthetase subunit alpha RHE_CH00881 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 86357932 Common - hypothetical protein RHE_CH02317 2 None None None 86356576 Common bioM biotin transporter, ATP-binding protein RHE_CH00930 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 86357978 Common - probable ribonuclease H protein RHE_CH02363 146 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 86357474 Common lldD2 L-lactate dehydrogenase (cytochrome) protein RHE_CH01847 112 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 86356128 Common - hypothetical conserved membrane protein RHE_CH00472 25 COG5500 COG5500, Predicted integral membrane protein Function unknown 86355796 Common - hypothetical protein RHE_CH00136 55 COG3807 COG3807, Uncharacterized protein conserved in bacteria Function unknown 86358423 Nonpathogen - hypothetical protein RHE_CH02820 1 None None None 86357656 Common - short chain dehydrogenase RHE_CH02037 226 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 86355740 Common - hypothetical protein RHE_CH00079 21 None None None 86356617 Common - probable zinc ABC transporter, substrate-binding protein RHE_CH00971 169 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 86358712 Common - hypothetical protein RHE_CH03111 11 None None None 86357404 Common alaS1 alanyl-tRNA synthetase protein RHE_CH01774 220 COG2872 COG2872, Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain General function prediction only 86356267 Common - putative DNA helicase protein RHE_CH00616 63 COG1273 COG1273, Uncharacterized conserved protein Function unknown 86356518 Common moaB molybdenum cofactor biosynthesis protein RHE_CH00872 173 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 86356691 Common - probable 3-oxoacyl-[acyl-carrier protein] reductase protein RHE_CH01047 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 86359106 Common cheBch2 chemotaxis-specific methylesterase protein RHE_CH03515 204 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 86359596 Common aniA carbon flux regulator protein RHE_CH04017 65 COG5394 COG5394, Uncharacterized protein conserved in bacteria Function unknown 86359069 Common ruvC Holliday junction resolvase RHE_CH03478 196 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 86358117 Nonpathogen - hypothetical protein RHE_CH02505 8 None None None 86358824 Common pssD glucuronosyltransferase protein RHE_CH03225 13 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 86359488 Common - hypothetical protein RHE_CH03907 27 COG3898 COG3898, Uncharacterized membrane-bound protein Function unknown 86358014 Common rbsCch4 ribose ABC transporter, permease protein RHE_CH02399 114 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 86356162 Common phoR phosphate regulon, two-component sensor histidine kinase protein RHE_CH00508 219 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 86356920 Common - hypothetical protein RHE_CH01280 49 COG3558 COG3558, Uncharacterized protein conserved in bacteria Function unknown 86357512 Common - hypothetical protein RHE_CH01891 34 COG2135 COG2135, Uncharacterized conserved protein Function unknown 86359282 Common - putative aldose-1-epimerase protein RHE_CH03692 29 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 86359193 Common soxBch sarcosine oxidase beta subunit protein RHE_CH03603 93 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 86357305 Common rplC 50S ribosomal protein L3 RHE_CH01675 217 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 86355811 Common polA DNA polymerase I RHE_CH00151 217 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 86356858 Common - hypothetical protein RHE_CH01218 55 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 86358330 Common afuA3 iron(III) ABC transporter, substrate-binding protein RHE_CH02725 92 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 86357091 Common - putative permease protein RHE_CH01453 101 COG0795 COG0795, Predicted permeases General function prediction only 86358298 Common - probable oxidoreductase protein RHE_CH02692 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 86359367 Common - putative endonuclease protein RHE_CH03784 99 COG1403 McrA, Restriction endonuclease Defense mechanisms 86357194 Common - probable sugar ABC transporter, permease protein RHE_CH01557 163 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 86356362 Common - hypothetical protein RHE_CH00711 6 None None None 86357996 Common gph2 phosphoglycolate phosphatase RHE_CH02381 190 COG0546 Gph, Predicted phosphatases General function prediction only 86356410 Common - putative beta-glycosyltransferase protein RHE_CH00761 185 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 86357391 Common - putative sensory box/GGDEF family protein RHE_CH01761 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 86358912 Nonpathogen - hypothetical protein RHE_CH03313 2 None None None 86357624 Nonpathogen - hypothetical protein RHE_CH02004 1 None None None 86358984 Common - probable exopolysaccharide polymerization/transport protein RHE_CH03386 82 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 86358852 Common - probable ABC transporter, permease protein RHE_CH03253 163 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 86357731 Nonpathogen - hypothetical protein RHE_CH02112 1 None None None 86359338 Common - hypothetical protein RHE_CH03754 31 COG5373 COG5373, Predicted membrane protein Function unknown 86355751 Common uxaC glucuronate isomerase RHE_CH00090 60 COG1904 UxaC, Glucuronate isomerase Carbohydrate transport and metabolism 86356170 Common argD bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein RHE_CH00516 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 86356091 Common - hypothetical protein RHE_CH00434 3 None None None 86356217 Common - probable transporter, permease protein RHE_CH00564 62 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86359696 Common holA DNA polymerase III subunit delta RHE_CH04118 34 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 86356005 Common - hypothetical protein RHE_CH00348 7 None None None 86356866 Common ptrB protease II protein RHE_CH01226 110 COG1770 PtrB, Protease II Amino acid transport and metabolism 86355859 Common - hypothetical protein RHE_CH00200 14 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 86359012 Common adeC2 adenine deaminase protein RHE_CH03420 94 COG1001 AdeC, Adenine deaminase Nucleotide transport and metabolism 86357846 Common - hypothetical conserved membrane protein RHE_CH02231 26 COG2259 COG2259, Predicted membrane protein Function unknown 86359529 Nonpathogen cycX probable heme transporter protein (involved in cytochrome-c biogenesis) RHE_CH03949 1 None None None 86359558 Common lonD ATP-dependent protease LA 2 protein RHE_CH03978 43 COG2802 COG2802, Uncharacterized protein, similar to the N-terminal domain of Lon protease General function prediction only 86355755 Common - probable transcriptional regulator protein, MerR family RHE_CH00094 99 COG0789 SoxR, Predicted transcriptional regulators Transcription 86359388 Common plsC 1-acyl-sn-glycerol-3-phosphate acyltransferase protein RHE_CH03805 158 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 86357802 Common tpiAch triosephosphate isomerase protein RHE_CH02186 215 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 86358697 Common oppA oligopeptide ABC transporter, substrate-binding protein RHE_CH03096 214 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 86358999 Common - phosphoribosyltransferase RHE_CH03407 6 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 86358796 Common - probable glycosyltransferase protein RHE_CH03196 122 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 86358137 Common rrpX two-component response regulator protein RHE_CH02527 211 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 86358603 Common - hypothetical protein RHE_CH03001 18 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 86357856 Common gcvT aminomethyltransferase protein RHE_CH02241 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 86357887 Common - hypothetical protein RHE_CH02272 4 None None None 86358156 Common mcpV3 methyl-accepting chemotaxis protein RHE_CH02547 153 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 86359301 Common exsB succinoglycan biosynthesis transcriptional regulator protein RHE_CH03711 168 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 86358370 Common - putative antibiotic resistance permease protein RHE_CH02766 68 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86357261 Common dnaE DNA polymerase III subunit alpha RHE_CH01627 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 86356847 Nonpathogen - hypothetical protein RHE_CH01207 3 COG1737 RpiR, Transcriptional regulators Transcription 86357942 Common - hypothetical protein RHE_CH02327 4 None None None 86358534 Common - hypothetical protein RHE_CH02932 2 None None None 86359393 Common hisCch2 histidinol-phosphate aminotransferase RHE_CH03810 239 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 86355715 Common hisB imidazoleglycerol-phosphate dehydratase RHE_CH00047 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 86356461 Common tag DNA-3-methyladenine glycosylase I protein RHE_CH00815 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 86357177 Common - probable insertion sequence transposase protein, ISRM11/ISRM2011-2 element RHE_CH01539 21 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 86356065 Common mcpX1 methyl-accepting chemotaxis protein RHE_CH00408 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 86359129 Common - putative transcriptional regulator protein, LysR family RHE_CH03538 187 COG0583 LysR, Transcriptional regulator Transcription 86359256 Common - hypothetical conserved membrane protein RHE_CH03666 40 COG4291 COG4291, Predicted membrane protein Function unknown 86356103 Nonpathogen - hypothetical protein RHE_CH00447 1 None None None 86356757 Nonpathogen - hypothetical protein RHE_CH01115 1 None None None 86357642 Common - hypothetical protein RHE_CH02023 120 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 86357608 Nonpathogen - hypothetical protein RHE_CH01988 1 None None None 86357364 Common - probable two-component response regulator protein RHE_CH01734 201 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 86358078 Common - hypothetical protein RHE_CH02466 20 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 86356469 Common hisG ATP phosphoribosyltransferase catalytic subunit RHE_CH00823 204 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 86357918 Nonpathogen - hypothetical protein RHE_CH02303 1 None None None 86357044 Common - hypothetical protein RHE_CH01406 16 COG5451 COG5451, Predicted secreted protein Function unknown 86355876 Common - putative endopeptidase-related protein RHE_CH00217 105 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 86358803 Nonpathogen - hypothetical protein RHE_CH03203 1 None None None 86355762 Common - hypothetical protein RHE_CH00102 18 COG3619 COG3619, Predicted membrane protein Function unknown 86359016 Common - short chain dehydrogenase RHE_CH03424 86 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 86357798 Nonpathogen - hypothetical protein RHE_CH02181 5 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 86358943 Nonpathogen - hypothetical conserved membrane protein RHE_CH03345 1 None None None 86358399 Common degPch4 serine protease DO-like protein RHE_CH02795 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 86359383 Common hpt hypoxanthine phosphoribosyltransferase protein RHE_CH03800 152 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 86358046 Common - probable 3-hydroxyisobutyrate dehydrogenase protein RHE_CH02433 193 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 86357164 Common nusB transcription antitermination protein NusB RHE_CH01526 185 COG0781 NusB, Transcription termination factor Transcription 86358570 Common - hypothetical protein RHE_CH02968 55 COG4277 COG4277, Predicted DNA-binding protein with the Helix-hairpin-helix motif General function prediction only 86358575 Common dctD two-component response regulator protein regulating C4-dicarboxylate transport system RHE_CH02973 212 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 86356998 Common - probable dTDP-glucose 4,6-dehydratase protein RHE_CH01360 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 86357101 Common - probable amino acid ABC transporter, permease protein RHE_CH01463 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 86358780 Common - probable potassium channel protein RHE_CH03180 130 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 86356304 Common fliM flagellar C-ring protein RHE_CH00653 11 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 86359181 Common - putative transglutaminase-like protein RHE_CH03591 92 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 86356840 Common - hypothetical conserved membrane protein RHE_CH01200 25 COG0730 COG0730, Predicted permeases General function prediction only 86359099 Common - hypothetical protein RHE_CH03508 65 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 86359188 Common glgXch glycosyl hydrolase (glycogen debranching) protein RHE_CH03598 128 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 86356509 Common atpI ATP synthase protein, subunit I RHE_CH00863 29 COG5336 COG5336, Uncharacterized protein conserved in bacteria Function unknown 86358262 Common lacZ1 beta-D-galactosidase protein RHE_CH02656 40 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 86358887 Common - probable two-component response regulator protein RHE_CH03288 18 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 86357279 Common rne ribonuclease E protein RHE_CH01645 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 86355672 Common aroE shikimate 5-dehydrogenase RHE_CH00003 225 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 86357267 Common pleD response regulator PleD RHE_CH01633 224 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 86356741 Nonpathogen - hypothetical protein RHE_CH01098 1 None None None 86356583 Common gpmB phosphoglycerate mutase protein RHE_CH00937 142 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 86359208 Common - putative TRAP mannitol/C4-dicarboxylate transporter, permease protein RHE_CH03618 135 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 86356950 Common - putative permease protein RHE_CH01310 71 COG2962 RarD, Predicted permeases General function prediction only 86356075 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase RHE_CH00418 142 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 86358342 Common - putative SAM-dependent methyltransferase protein RHE_CH02737 31 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 162329630 Common map2 methionine aminopeptidase RHE_CH03116 246 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 86359672 Common - putative phosphatase protein RHE_CH04094 57 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 86356555 Common - putative transcriptional regulator protein RHE_CH00909 143 COG1733 COG1733, Predicted transcriptional regulators Transcription 86358789 Common - probable sugar ABC transporter, permease protein RHE_CH03189 143 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 86356598 Common ctaC cytochrome-c oxidase, subunit II protein RHE_CH00952 143 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 86359360 Common - probable monocarboxylate transporter, permease protein RHE_CH03776 105 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 86359177 Common - probable two-component response regulator protein RHE_CH03587 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 86357433 Nonpathogen - hypothetical protein RHE_CH01803 2 None None None 86356816 Common - hypothetical protein RHE_CH01176 28 COG4312 COG4312, Uncharacterized protein conserved in bacteria Function unknown 86356829 Common - probable alcohol dehydrogenase protein RHE_CH01189 214 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 86357526 Nonpathogen - hypothetical protein RHE_CH01905 12 COG5490 COG5490, Uncharacterized conserved protein Function unknown 86355724 Common actS two-component sensor histidine kinase protein RHE_CH00056 214 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 86355846 Common - probable outer membrane lipoprotein RHE_CH00187 107 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 86358521 Common - probable integrase/recombinase protein RHE_CH02919 21 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 86357694 Common - putative ABC transporter, ATP-binding protein RHE_CH02075 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 86358552 Common sigA RNA polymerase sigma factor RpoD RHE_CH02950 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 86357133 Common rnd2 RNase D protein RHE_CH01495 123 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 86357258 Common - probable lipoprotein ABC transporter, permease protein RHE_CH01624 189 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 86356393 Common - probable chalcone synthase protein RHE_CH00744 151 COG3424 BcsA, Predicted naringenin-chalcone synthase Secondary metabolites biosynthesis, transport, and catabolism 86359200 Common - hypothetical protein RHE_CH03610 11 None None None 86358844 Nonpathogen - hypothetical protein RHE_CH03245 1 None None None 86357758 Common occPch octopine ABC transporter, ATP-binding protein RHE_CH02139 249 COG4598 HisP, ABC-type histidine transport system, ATPase component Amino acid transport and metabolism 86356329 Common - probable two-component response regulator protein RHE_CH00678 80 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 86355943 Common - hypothetical protein RHE_CH00285 25 COG3608 COG3608, Predicted deacylase General function prediction only 162329641 Common - probable DNA-methyltransferase protein (hemagglutinin-associated protein) RHE_CH01977 117 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 86356480 Common codAch1 cytosine deaminase protein RHE_CH00834 200 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 86359331 Common nuoF2 NADH-ubiquinone oxidoreductase chain F protein RHE_CH03741 167 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 86355929 Common - probable oxidoreductase protein, aldo/keto reductase family RHE_CH00271 200 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 86358000 Common fumB fumarate hydratase class I protein RHE_CH02385 148 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 86357339 Common - hypothetical protein RHE_CH01709 6 None None None 86356793 Common - hypothetical protein RHE_CH01151 11 COG3860 COG3860, Uncharacterized protein conserved in bacteria Function unknown 86358859 Common - hypothetical protein RHE_CH03260 9 COG2363 COG2363, Uncharacterized small membrane protein Function unknown 86358323 Common - putative superoxide dismutase SodM-like protein RHE_CH02717 29 COG4275 COG4275, Uncharacterized conserved protein Function unknown 86358674 Common - probable cation efflux protein RHE_CH03072 199 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 86359520 Common - hypothetical protein RHE_CH03940 130 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 86357479 Common - probable holliday junction resolvase protein RHE_CH01852 156 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 86356439 Common - putative beta-lactamase family protein RHE_CH00793 65 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 86357981 Common - hypothetical protein RHE_CH02366 45 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 86358686 Common proX proline/glycine betaine ABC transporter, substrate-binding protein RHE_CH03085 61 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 86359347 Common comF competence protein F (phosphoribosyltransferase protein) RHE_CH03763 180 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 86359266 Common - probable L-ribulokinase protein RHE_CH03676 167 COG1069 AraB, Ribulose kinase Energy production and conversion 86358419 Common - hypothetical protein RHE_CH02816 71 COG2718 COG2718, Uncharacterized conserved protein Function unknown 86359246 Common gltX glutamyl-tRNA synthetase RHE_CH03656 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 86356287 Common mcpE methyl-accepting chemotaxis protein RHE_CH00636 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 86358528 Nonpathogen - hypothetical protein RHE_CH02926 1 None None None 86356891 Common - hypothetical protein RHE_CH01251 7 None None None 86355699 Common ahcY S-adenosyl-L-homocysteine hydrolase RHE_CH00031 177 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 86358270 Nonpathogen - hypothetical protein RHE_CH02664 3 None None None 86355852 Common deoC 2-deoxyribose-5-phosphate aldolase protein RHE_CH00193 138 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 86357326 Common adk adenylate kinase (ATP-AMP transphosphorylase) protein RHE_CH01696 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 86355905 Common - hypothetical protein RHE_CH00247 46 COG3791 COG3791, Uncharacterized conserved protein Function unknown 86359416 Common hipO hyppurate hydrolase protein RHE_CH03833 166 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 86359651 Common modC molybdenum ABC transporter, ATP-binding protein RHE_CH04073 249 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 86356199 Common - hypothetical protein RHE_CH00546 81 COG2128 COG2128, Uncharacterized conserved protein Function unknown 86357024 Common - hypothetical protein RHE_CH01386 3 None None None 86358377 Common - putative carboxymuconolactone decarboxylase protein RHE_CH02773 81 COG2128 COG2128, Uncharacterized conserved protein Function unknown 86358189 Nonpathogen - hypothetical protein RHE_CH02580 1 None None None 86356343 Common cpsF N-acetyl mannosamine transferase protein RHE_CH00692 110 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 86359122 Common purE phosphoribosylaminoimidazole carboxylase catalytic subunit protein RHE_CH03531 231 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 86359359 Common - putative transcriptional regulator protein, TetR family RHE_CH03775 101 COG1309 AcrR, Transcriptional regulator Transcription 86356944 Common - probable multidrug efflux transporter protein, AcrB/AcrD/AcrF family RHE_CH01304 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 86355780 Common - putative ABC transporter, permease protein RHE_CH00120 99 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86356662 Nonpathogen - hypothetical protein RHE_CH01017 1 None None None 86358417 Common cyaJ adenylate cyclase protein RHE_CH02814 53 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 86356940 Common - hypothetical protein RHE_CH01300 5 None None None 86359621 Common kamA L-lysine 2,3-aminomutase protein RHE_CH04042 125 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 86358744 Common - hypothetical protein RHE_CH03143 27 None None None 86357343 Common - putative nucleoside 2-deoxyribosyltransferase protein RHE_CH01713 19 COG3613 COG3613, Nucleoside 2-deoxyribosyltransferase Nucleotide transport and metabolism 86359144 Common hss homospermidine synthase protein RHE_CH03553 25 COG5310 COG5310, Homospermidine synthase Secondary metabolites biosynthesis, transport, and catabolism 86357041 Common - putative hydrolase protein RHE_CH01403 31 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 86359606 Common - putative metalloprotease protein RHE_CH04027 130 COG4784 COG4784, Putative Zn-dependent protease General function prediction only 86357467 Common - hypothetical conserved membrane protein RHE_CH01839 7 COG4872 COG4872, Predicted membrane protein Function unknown 86359619 Common efp elongation factor P RHE_CH04040 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 86356775 Common - putative transcriptional regulator protein RHE_CH01133 173 COG1959 COG1959, Predicted transcriptional regulator Transcription 86355919 Common rpmI 50S ribosomal protein L35 RHE_CH00261 39 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 86358865 Nonpathogen - hypothetical protein RHE_CH03266 6 None None None 86355935 Common - probable NAD(P)H dehydrogenase (quinone) protein RHE_CH00277 75 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 86356820 Common - probable ABC transporter, ATP-binding protein RHE_CH01180 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 86357311 Common rpsC 30S ribosomal protein S3 RHE_CH01681 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 86356082 Common lldD1 L-lactate dehydrogenase (cytochrome) protein RHE_CH00425 113 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 86356359 Common mcpZch1 methyl-accepting chemotaxis protein RHE_CH00708 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 86357325 Common secY preprotein translocase subunit SecY RHE_CH01695 231 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 86359533 Common ftsY cell division protein RHE_CH03953 246 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 86359659 Common bfr bacterioferritin protein RHE_CH04081 108 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 86359077 Common - hypothetical protein RHE_CH03486 79 COG2898 COG2898, Uncharacterized conserved protein Function unknown 86357539 Common cdsAch phosphatidate cytidylyltransferase protein RHE_CH01918 213 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 86356980 Common iolB myo-inositol catabolism protein RHE_CH01341 53 COG3718 IolB, Uncharacterized enzyme involved in inositol metabolism Carbohydrate transport and metabolism 86357460 Common secD2 bifunctional preprotein translocase subunit SecD/SecF RHE_CH01832 207 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 86357491 Common - NADH dehydrogenase RHE_CH01865 38 COG3761 COG3761, NADH:ubiquinone oxidoreductase 17.2 kD subunit Energy production and conversion 86357319 Common rpsH 30S ribosomal protein S8 RHE_CH01689 248 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 86358309 Common - putative isoprenylcysteine carboxyl methyltransferase protein RHE_CH02703 17 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 86358842 Common noeK phosphomannomutase protein RHE_CH03243 233 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 86357048 Common pssA1 CDP-diacylglycerol-serine O-phosphatidyltransferase protein RHE_CH01410 143 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 86358776 Nonpathogen - hypothetical protein RHE_CH03176 1 None None None 86357925 Common - hypothetical protein RHE_CH02310 129 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 86357741 Common - putative hydrolase protein, MutT/nudix family RHE_CH02122 24 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 86357035 Common - putative metal-dependent phosphohydrolase protein RHE_CH01397 59 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 86357374 Common - probable transcriptional regulator protein, AsnC family RHE_CH01744 136 COG1522 Lrp, Transcriptional regulators Transcription 86357330 Common rplQ 50S ribosomal protein L17 RHE_CH01700 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 86359634 Common - probable aldehyde dehydrogenase protein RHE_CH04055 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 86356570 Common ectC L-ectoine synthase RHE_CH00924 35 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 86358173 Nonpathogen - hypothetical protein RHE_CH02564 1 None None None 86359345 Common - putative amidohydrolase protein RHE_CH03761 201 COG0388 COG0388, Predicted amidohydrolase General function prediction only 86356411 Common noeL1 GDP-mannose 4,6-dehydratase protein RHE_CH00762 227 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 86358335 Common ilvE2 branched-chain amino acid aminotransferase RHE_CH02730 209 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 86357992 Common gor glutathione reductase RHE_CH02377 245 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 86358947 Common mexE1 multidrug-efflux system secretion protein, HlyD family RHE_CH03349 162 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 86357155 Common - putative nucleotide sugar transaminase protein RHE_CH01517 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 86356831 Common - probable transcriptional regulator protein, LysR family RHE_CH01191 175 COG0583 LysR, Transcriptional regulator Transcription 86359684 Common - hypothetical conserved membrane protein RHE_CH04106 72 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 86357725 Common - probable acetyltransferase protein RHE_CH02106 23 COG0456 RimI, Acetyltransferases General function prediction only 86358253 Common - probable menaquinone biosynthesis methyltransferase protein RHE_CH02647 117 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 86358008 Nonpathogen - hypothetical protein RHE_CH02393 1 None None None 86355689 Common trpB tryptophan synthase subunit beta RHE_CH00021 225 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 86358902 Common - probable urease-associated protein RHE_CH03303 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 86359504 Common argG2 argininosuccinate synthase RHE_CH03924 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 86356817 Common - hypothetical protein RHE_CH01177 9 None None None 86357752 Common - putative acetyltransferase protein, GNAT family RHE_CH02133 15 COG3393 COG3393, Predicted acetyltransferase General function prediction only 86359546 Common - probable oxidoreductase protein, aldo/keto reductase family RHE_CH03966 180 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 86356911 Common groEL chaperonin GroEL RHE_CH01271 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 86357769 Common - putative mechanosensitive ion channel protein RHE_CH02151 145 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 86358275 Common - putative acetyltransferase protein RHE_CH02669 4 None None None 86356523 Common - putative methyltransferase protein RHE_CH00877 38 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 86355700 Common - probable phosphocarrier protein HPr protein (component of the phosphoenolpyruvate-dependent sugarphosphotransferase system) RHE_CH00032 93 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 86357761 Common - probable transcriptional regulator protein RHE_CH02142 130 COG1802 GntR, Transcriptional regulators Transcription 86358087 Common - 3-oxoacyl-(acyl carrier protein) synthase II RHE_CH02475 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 86356379 Common - probable transcriptional regulator protein, LysR family RHE_CH00729 163 COG0583 LysR, Transcriptional regulator Transcription 86357446 Common argS arginyl-tRNA synthetase RHE_CH01818 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 86358385 Nonpathogen - hypothetical protein RHE_CH02781 8 None None None 86357698 Common pcs phosphatidylcholine synthase protein RHE_CH02079 43 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 162329639 Common gyrA DNA gyrase subunit A RHE_CH02110 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 86356928 Common lppA outer membrane lipoprotein-related protein RHE_CH01288 19 COG4520 LipA, Surface antigen Cell envelope biogenesis, outer membrane 86359058 Common - probable 4-hydroxybenzoyl-CoA thioesterase protein RHE_CH03467 126 COG0824 FcbC, Predicted thioesterase General function prediction only 86356695 Common - hypothetical protein RHE_CH01051 11 None None None 86358143 Common - putative glycerol uptake transporter protein, MIP family RHE_CH02533 85 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 86358435 Common creA CreA protein RHE_CH02832 56 COG3045 CreA, Uncharacterized protein conserved in bacteria Function unknown 86357013 Common - probable cobalamin synthesis protein, P47K family RHE_CH01375 129 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 86357357 Common - probable dehydrogenase protein RHE_CH01727 76 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 86358125 Common - hypothetical protein RHE_CH02513 25 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 86358315 Common zur zinc uptake transcriptional regulator protein, Fur family RHE_CH02709 88 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 86357498 Common - probable outer membrane protein RHE_CH01872 98 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 86358497 Common - probable sugar ABC transporter, ATP-binding protein RHE_CH02894 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 86359254 Common - probable betaine-aldehyde dehydrogenase protein RHE_CH03664 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 86358485 Common - hypothetical protein RHE_CH02882 90 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 86355893 Common - hypothetical protein RHE_CH00234 5 None None None 86357059 Common - hypothetical protein RHE_CH01421 68 COG3791 COG3791, Uncharacterized conserved protein Function unknown 86359458 Common - putative acetyltransferase protein, GNAT family RHE_CH03877 11 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 86356500 Common dgoK 2-dehydro-3-deoxygalactonokinase protein RHE_CH00854 40 COG3734 DgoK, 2-keto-3-deoxy-galactonokinase Carbohydrate transport and metabolism 86356493 Common - hypothetical protein RHE_CH00847 23 COG3908 COG3908, Uncharacterized protein conserved in bacteria Function unknown 86356970 Common - probable glyoxalase protein RHE_CH01330 20 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 86359114 Common cheY3 chemotaxis two-component response regulator protein RHE_CH03523 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 86358206 Common - probable pyridoxal-dependent amino acid decarboxylase protein RHE_CH02599 93 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 86356296 Common - hypothetical protein RHE_CH00645 3 None None None 86358080 Common gnd 6-phosphogluconate dehydrogenase RHE_CH02468 176 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 86358231 Common - putative calmodulin-binding protein RHE_CH02624 4 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 86357213 Common - hypothetical protein RHE_CH01576 120 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 86358721 Common - probable RNA polymerase sigma factor protein (sigma-70) RHE_CH03120 44 COG4941 COG4941, Predicted RNA polymerase sigma factor containing a TPR repeat domain Transcription 86355819 Common - probable phosphonate ABC transporter, substrate-binding protein RHE_CH00159 81 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 86356536 Common glyS glycyl-tRNA synthetase subunit beta RHE_CH00890 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 86357867 Common - putative endonuclease protein RHE_CH02252 35 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 86355887 Common egl endoglucanase precursor (cellulase) protein RHE_CH00228 7 COG2730 BglC, Endoglucanase Carbohydrate transport and metabolism 86358810 Common pssV exopolysaccharide production protein RHE_CH03210 3 None None None 86359302 Common exsC 6-pyruvoyl tetrahydropterin synthase protein RHE_CH03712 101 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 86356473 Nonpathogen - hypothetical protein RHE_CH00827 1 None None None 86359561 Nonpathogen - putative insertion sequence transposase protein RHE_CH03982 2 None None None 86358610 Common - putative transcriptional regulator protein RHE_CH03008 131 COG1733 COG1733, Predicted transcriptional regulators Transcription 86356141 Common - probable glycine betaine ABC transporter, substrate binding protein RHE_CH00485 85 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 86357968 Common - putative phosphoglycerate mutase protein RHE_CH02353 36 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 86358690 Common nolRch transcriptional regulator protein (repressor of nodulation genes), ArsR family RHE_CH03089 148 COG0640 ArsR, Predicted transcriptional regulators Transcription 86356551 Common - probable acyl-CoA dehydrogenase protein RHE_CH00905 150 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 86358069 Common manB2 beta-mannosidase protein RHE_CH02457 47 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 86358562 Common - probable amino acid ABC transporter, substrate-binding protein RHE_CH02960 153 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 86355912 Common recX recombination regulator RecX RHE_CH00254 9 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 86358879 Common - hypothetical protein RHE_CH03280 3 None None None 86358689 Common - hypothetical protein RHE_CH03088 44 COG0748 HugZ, Putative heme iron utilization protein Inorganic ion transport and metabolism 86357405 Common cysK2 cysteine synthase A RHE_CH01775 224 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 86359597 Common phbAch acetyl-CoA acetyltransferase RHE_CH04018 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 86357215 Nonpathogen - hypothetical protein RHE_CH01578 1 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 86355834 Common mepA penicillin-insensitive murein endopeptidase RHE_CH00174 40 COG3770 MepA, Murein endopeptidase Cell envelope biogenesis, outer membrane 86356089 Common - probable two-component sensor histidine kinase protein RHE_CH00432 94 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 86356272 Common - hypothetical protein RHE_CH00621 30 COG4529 COG4529, Uncharacterized protein conserved in bacteria Function unknown 86356989 Common - probable exopolysaccharide biosynthesis protein RHE_CH01351 138 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 86358457 Common - hypothetical protein RHE_CH02854 14 COG5462 COG5462, Predicted secreted (periplasmic) protein Function unknown 86357714 Common mfd transcription-repair coupling factor (TRCF) protein RHE_CH02095 216 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 86358911 Common - probable urea or short-chain amide ABC transporter, ATP-binding protein RHE_CH03312 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 86358636 Common - putative enoyl-CoA hydratase protein RHE_CH03034 47 COG2030 MaoC, Acyl dehydratase Lipid metabolism 86356565 Common matR transcriptional regulator (activator) protein, AsnC/GntR family RHE_CH00919 119 COG1802 GntR, Transcriptional regulators Transcription 86358516 Common - hypothetical protein RHE_CH02913 4 None None None 86355991 Common - probable protein secretion protein, HlyD family RHE_CH00334 113 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 86358354 Common glpQ glycerophosphoryl diester phosphodiesterase protein RHE_CH02749 154 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 86358875 Common tcrY two-component sensor histidine kinase protein RHE_CH03276 33 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 86357028 Common rnc ribonuclease III RHE_CH01390 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 86358228 Common - putative metallo-beta-lactamase family protein RHE_CH02621 191 COG3453 COG3453, Uncharacterized protein conserved in bacteria Function unknown 86356240 Common nhaA Na+/H+ antiporter protein RHE_CH00589 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 86356535 Common - hypothetical protein RHE_CH00889 61 COG1683 COG1683, Uncharacterized conserved protein Function unknown 86357985 Common - putative periplasmic component of the Tol biopolymer transport system RHE_CH02370 130 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 86356738 Nonpathogen - hypothetical protein RHE_CH01095 2 None None None 86357910 Common - probable amino acid ABC transporter, permease protein RHE_CH02295 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 86355765 Common - hypothetical conserved membrane protein RHE_CH00105 132 COG2860 COG2860, Predicted membrane protein Function unknown 86358831 Common - hypothetical protein RHE_CH03232 2 None None None 86356997 Common - putative sugar transferase involved in lipopolysaccharide synthesis, UDP-galactose-lipid carriertransferase protein RHE_CH01359 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 86357388 Common - hypothetical protein RHE_CH01758 9 None None None 86356720 Common - hypothetical protein RHE_CH01077 56 COG3791 COG3791, Uncharacterized conserved protein Function unknown 86359194 Nonpathogen - hypothetical protein RHE_CH03604 14 COG4254 COG4254, Uncharacterized protein conserved in bacteria Function unknown 86359340 Common prfA peptide chain release factor 1 RHE_CH03756 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 86359420 Common - hypothetical protein RHE_CH03838 3 None None None 86358682 Nonpathogen - hypothetical protein RHE_CH03081 1 None None None 86356249 Common - hypothetical protein RHE_CH00598 15 COG5467 COG5467, Uncharacterized conserved protein Function unknown 86358962 Common - hypothetical protein RHE_CH03364 171 COG1959 COG1959, Predicted transcriptional regulator Transcription 86357689 Common - probable sugar ABC transporter, permease protein RHE_CH02070 144 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 86356422 Common - probable insertion sequence transposase protein, IS66 family RHE_CH00773 39 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 86359062 Common - probable 5-formyltetrahydrofolate cyclo-ligase protein RHE_CH03471 181 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 86355828 Common - probable transcriptional regulator protein, GntR family RHE_CH00168 113 COG2188 PhnF, Transcriptional regulators Transcription 86359435 Common cheW5 chemotaxis signal transduction protein RHE_CH03853 134 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 86359479 Nonpathogen - hypothetical protein RHE_CH03898 1 None None None 86357565 Common cinA2 competence-damage associated protein RHE_CH01944 192 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 86358930 Common - putative acetyltransferase protein RHE_CH03332 55 COG2388 COG2388, Predicted acetyltransferase General function prediction only 86356733 Nonpathogen - hypothetical protein RHE_CH01090 1 None None None 86359243 Common - probable transcriptional regulator protein, TetR family RHE_CH03653 146 COG1309 AcrR, Transcriptional regulator Transcription 86357575 Common hfq RNA-binding protein Hfq RHE_CH01954 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 86356707 Common - probable carbonic anhydrase protein RHE_CH01064 154 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 86358630 Common pth peptidyl-tRNA hydrolase RHE_CH03028 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 86359575 Common dppFch3 dipeptide ABC transporter, ATP-binding protein RHE_CH03996 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 86357199 Common - probable polysaccharide synthesis/transport transmembrane protein RHE_CH01562 77 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 86358421 Common - hypothetical protein RHE_CH02818 64 COG3865 COG3865, Uncharacterized protein conserved in bacteria Function unknown 86359327 Common nuoB3 NADH-ubiquinone oxidoreductase chain B protein RHE_CH03737 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 86359231 Nonpathogen - hypothetical protein RHE_CH03641 2 COG2259 COG2259, Predicted membrane protein Function unknown 86356481 Common rluB pseudouridylate synthase, subunit B protein RHE_CH00835 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 86358096 Common cobA uroporphyrin-III C-methyltransferase protein RHE_CH02484 200 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 86357306 Common rplD 50S ribosomal protein L4 RHE_CH01676 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 86358969 Common ugpAch2 sn-glycerol-3-phosphate ABC transporter, permease protein RHE_CH03371 143 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 86359153 Common - probable membrane-bound lytic murein transglycosylase protein RHE_CH03562 104 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 86356180 Common - putative protein secretion protein, HlyD family RHE_CH00527 105 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 86357944 Common dksA DnaK suppressor protein RHE_CH02329 160 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 86356228 Common - hypothetical protein RHE_CH00575 3 None None None 86358397 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase RHE_CH02793 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 86356129 Common - putative transcriptional regulator protein, TetR family RHE_CH00473 58 COG1309 AcrR, Transcriptional regulator Transcription 86356616 Common - probable zinc ABC transporter, permease protein RHE_CH00970 181 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 86357928 Common - hypothetical protein RHE_CH02313 32 COG0433 COG0433, Predicted ATPase General function prediction only 86358474 Common metF 5,10-methylenetetrahydrofolate reductase protein RHE_CH02871 143 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 86359035 Common pobR transcriptional regulator protein, AraC family RHE_CH03443 89 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 86357483 Common - hypothetical protein RHE_CH01857 5 None None None 86359650 Common modB molybdate ABC transporter permease protein RHE_CH04072 186 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 86356192 Common - hypothetical protein RHE_CH00539 43 COG3502 COG3502, Uncharacterized protein conserved in bacteria Function unknown 86359464 Common - putative amino acid efflux protein, LysE family RHE_CH03883 111 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 86355984 Common - putative transporter permease protein RHE_CH00327 46 COG2962 RarD, Predicted permeases General function prediction only 86357873 Common tyrS tyrosyl-tRNA synthetase RHE_CH02258 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 86357931 Common - hypothetical conserved membrane protein RHE_CH02316 9 COG1289 COG1289, Predicted membrane protein Function unknown 86357682 Common dppDch2 dipeptide ABC transporter, ATP-binding protein RHE_CH02063 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 86356558 Common mcpU methyl-accepting chemotaxis protein RHE_CH00912 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 86357634 Common - putative insertion sequence transposase protein RHE_CH02014 68 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 86358535 Common ropB2 outer membrane protein RHE_CH02933 26 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 86358986 Common exoF2 exopolysaccharide biosynthesis protein (OMA family outer membrane saccharide export protein) RHE_CH03388 57 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 86356517 Nonpathogen - hypothetical protein RHE_CH00871 7 None None None 86357399 Common aldR leucine-responsive transcriptional regulator protein, AsnC family RHE_CH01769 155 COG1522 Lrp, Transcriptional regulators Transcription 86356454 Common glcD glycolate oxidase subunit D protein RHE_CH00808 200 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 86358194 Common - putative transcriptional regulator protein RHE_CH02586 147 COG1733 COG1733, Predicted transcriptional regulators Transcription 86357836 Nonpathogen - hypothetical protein RHE_CH02220 2 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 86358757 Common - hypothetical protein RHE_CH03156 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 86356418 Common lpeA lipolysaccharide tri-O-methyl-fucosylation protein (SAM-dependent methyltransferase protein) RHE_CH00769 11 COG2520 COG2520, Predicted methyltransferase General function prediction only 86358781 Common - putative membrane-located cell surface saccharide saccharide acetylase protein, acyltransferase family RHE_CH03181 101 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 86356661 Common - hypothetical protein RHE_CH01016 3 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 86355864 Common cpaC pilus assembly secretion protein RHE_CH00205 130 COG4964 CpaC, Flp pilus assembly protein, secretin CpaC Intracellular trafficking and secretion 86356382 Common exoR1 exopolysaccharide production negative regulator protein RHE_CH00733 41 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 86356402 Common wzm polysaccharide ABC transporter, permease protein RHE_CH00753 106 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 86357779 Common dac D-alanyl-D-alanine carboxypeptidase protein RHE_CH02161 144 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 86356131 Common frk fructokinase protein RHE_CH00475 156 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 86358582 Common - probable antibiotic resistance (streptomycin kinase) protein RHE_CH02980 27 COG3570 StrB, Streptomycin 6-kinase Defense mechanisms 86358807 Common - hypothetical protein RHE_CH03207 23 COG3629 DnrI, DNA-binding transcriptional activator of the SARP family Signal transduction mechanisms 86356603 Common - hypothetical protein RHE_CH00957 3 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 86357676 Common - 5-dehydro-4-deoxyglucarate dehydratase RHE_CH02057 217 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 86357066 Common purF amidophosphoribosyltransferase RHE_CH01428 239 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 86357957 Common - hypothetical protein RHE_CH02342 12 COG0645 COG0645, Predicted kinase General function prediction only 86358800 Common - probable glycosyltransferase protein RHE_CH03200 220 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 86358666 Common - hypothetical protein RHE_CH03064 10 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 86357561 Common - hypothetical conserved membrane protein RHE_CH01940 14 COG2261 COG2261, Predicted membrane protein Function unknown 86356577 Common - hypothetical protein RHE_CH00931 61 COG3214 COG3214, Uncharacterized protein conserved in bacteria Function unknown 86356871 Nonpathogen - hypothetical protein RHE_CH01231 1 None None None 86359582 Common - putative reductase protein RHE_CH04003 22 COG0431 COG0431, Predicted flavoprotein General function prediction only 86358579 Common - probable transcriptional regulator protein, ArsR family RHE_CH02977 54 COG0640 ArsR, Predicted transcriptional regulators Transcription 86358738 Common - hypothetical protein RHE_CH03137 14 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 86358816 Common pssK exopolysaccharide polymerization protein RHE_CH03217 20 COG5039 COG5039, Exopolysaccharide biosynthesis protein Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 86356878 Common groESch2 10 kDa chaperonin, heat shock protein RHE_CH01238 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 86357078 Common rpsF 30S ribosomal protein S6 RHE_CH01440 197 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 86358750 Common dapAch4 dihydrodipicolinate synthase protein RHE_CH03149 194 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 86357844 Common - hypothetical protein RHE_CH02229 90 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 86359209 Common - probable TRAP mannitol/C4-dicarboxylate transporter, substrate-binding protein RHE_CH03619 84 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 86355805 Common dnaK chaperone protein (Heat shock protein 70) RHE_CH00145 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 86358469 Common - hypothetical protein RHE_CH02866 11 COG5379 BtaA, S-adenosylmethionine:diacylglycerol 3-amino-3-carboxypropyl transferase Lipid metabolism 86359666 Common citEch citrate lyase, beta subunit protein RHE_CH04088 110 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 86356015 Common dnaA chromosomal replication initiation protein RHE_CH00358 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 86359165 Common - probable N-formylglutamate amidohydrolase protein RHE_CH03574 58 COG3741 HutG, N-formylglutamate amidohydrolase Amino acid transport and metabolism 86358163 Common - probable transcriptional regulator protein, LysR family RHE_CH02554 123 COG0583 LysR, Transcriptional regulator Transcription 86355802 Common - putative transcriptional regulator protein, Cro/CI family RHE_CH00142 38 COG1396 HipB, Predicted transcriptional regulators Transcription 86357591 Nonpathogen - hypothetical protein RHE_CH01971 1 None None None 86358952 Nonpathogen - hypothetical protein RHE_CH03354 1 None None None 86357411 Common nirD nitrite reductase [NAD(P)H], small subunit protein RHE_CH01781 88 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 86357534 Common rpsB 30S ribosomal protein S2 RHE_CH01913 222 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 86356020 Common rph ribonuclease PH RHE_CH00363 186 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 86356645 Common - putative thiol-disulfide oxidoreductase protein RHE_CH00999 85 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 86359467 Common - hypothetical protein RHE_CH03886 6 None None None 86357757 Common - putative adenylate/guanylate cyclase protein RHE_CH02138 111 COG3899 COG3899, Predicted ATPase General function prediction only 86359133 Common pykA pyruvate kinase RHE_CH03542 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 86359172 Common - hypothetical conserved membrane protein RHE_CH03582 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 86355979 Common gshB glutathione synthetase RHE_CH00322 139 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 86357740 Common - probable transcriptional regulator protein RHE_CH02121 138 COG1733 COG1733, Predicted transcriptional regulators Transcription 86357556 Common pdhB dihydrolipoamide acetyltransferase protein RHE_CH01935 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 86359299 Common - probable sugar ABC transporter, substrate-binding protein RHE_CH03709 52 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86358010 Common - probable transcriptional regulator protein RHE_CH02395 70 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 86358972 Common - probable sugar ABC transporter, substrate-binding protein RHE_CH03374 118 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86356547 Common - probable dioxygenase protein RHE_CH00901 81 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 86357109 Common ligE beta-aryl ether cleaving enzyme, lignin degradation protein RHE_CH01471 16 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 86358793 Common ampR transcriptional regulator protein (activator), LysR family RHE_CH03193 176 COG0583 LysR, Transcriptional regulator Transcription 86358408 Common dld D-lactate dehydrogenase (cytochrome) protein RHE_CH02804 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 86357178 Common - probable insertion sequence transposase protein, ISRM11/ISRM2011-2 element RHE_CH01540 46 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 86356341 Common - hypothetical protein RHE_CH00690 10 None None None 86359124 Common rpmJ 50S ribosomal protein L36 RHE_CH03533 72 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 86356787 Common - probable transcriptional regulator protein, DeoR family RHE_CH01145 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 86357148 Common ribD 5-amino-6-(5-phosphoribosylamino)uracil reductase/diaminohydroxyphosphoribosylaminopyrimidinedeaminase protein RHE_CH01510 222 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 86356375 Common - putative nucleotidyltransferase protein RHE_CH00725 10 COG1708 COG1708, Predicted nucleotidyltransferases General function prediction only 86358119 Common - probable cation efflux system protein (heavy metal efflux pump), CzcA family RHE_CH02507 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 86355954 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein RHE_CH00297 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 86357650 Common - putative gualylate cyclase protein RHE_CH02031 25 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 86358272 Common - probable transcriptional regulator protein, GntR family RHE_CH02666 212 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 86359179 Common - putative transglutaminase-like protein RHE_CH03589 87 COG4196 COG4196, Uncharacterized protein conserved in bacteria Function unknown 86355798 Common - probable D-2-hydroxyacid dehydrogenase protein RHE_CH00138 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 86356370 Common acsA1 acetyl-CoA synthetase RHE_CH00719 201 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 86356800 Common - probable transcriptional regulator protein RHE_CH01160 48 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 86356902 Common - hypothetical protein RHE_CH01262 74 COG2983 COG2983, Uncharacterized conserved protein Function unknown 86358040 Common - hypothetical protein RHE_CH02427 27 COG5649 COG5649, Uncharacterized conserved protein Function unknown 86357421 Common - probable anti-oxidant protein, AhpCTSA family RHE_CH01791 217 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 86358591 Common - hypothetical protein RHE_CH02989 37 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 86356979 Nonpathogen - probable transcriptional regulator protein RHE_CH01340 2 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 86358388 Nonpathogen - hypothetical protein RHE_CH02784 1 None None None 86356000 Common - short chain dehydrogenase RHE_CH00343 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 86356653 Common - hypothetical protein RHE_CH01007 13 None None None 86359356 Common - hypothetical protein RHE_CH03772 18 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 86357521 Common nah salicylate hydroxylase protein RHE_CH01900 75 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 86356204 Common - hypothetical protein RHE_CH00551 38 COG4764 COG4764, Uncharacterized protein conserved in bacteria Function unknown 86356179 Common - probable transcriptional regulator protein, TetR family RHE_CH00526 72 COG1309 AcrR, Transcriptional regulator Transcription 86358548 Common - probable transcriptional regulator protein, AraC family RHE_CH02946 104 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 86357813 Common - hypothetical protein RHE_CH02197 22 COG3797 COG3797, Uncharacterized protein conserved in bacteria Function unknown 86359261 Common nth endonuclease III protein RHE_CH03671 240 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 86358885 Common - probable transcriptional regulator protein, LysR family RHE_CH03286 175 COG0583 LysR, Transcriptional regulator Transcription 86359224 Common - hypothetical protein RHE_CH03634 34 COG2979 COG2979, Uncharacterized protein conserved in bacteria Function unknown 86358918 Common - probable two-component response regulator protein RHE_CH03320 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 86357893 Common purC1 phosphoribosylaminoimidazole-succinocarboxamide synthase RHE_CH02278 169 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 86358379 Common - hypothetical protein RHE_CH02775 20 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 86359009 Common potC spermidine/putrescine ABC transporter, permease component II protein RHE_CH03417 221 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 86356591 Common - hypothetical protein RHE_CH00945 4 COG1694 MazG, Predicted pyrophosphatase General function prediction only 86359268 Common mtlK mannitol 2-dehydrogenase protein RHE_CH03678 91 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 86357704 Common - probable sugar ABC transporter, substrate-binding protein RHE_CH02085 114 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86358089 Common - probable hydroxymyristoyl-[acyl carrier] dehydratase transmembrane protein RHE_CH02477 179 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 86357930 Common - probable tRNA/rRNA methyltransferase protein RHE_CH02315 154 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 86358044 Common - probable transcriptional regulator protein, ArsR family RHE_CH02431 115 COG0640 ArsR, Predicted transcriptional regulators Transcription 86356552 Common - enoyl-CoA hydratase RHE_CH00906 168 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 86356679 Nonpathogen - hypothetical protein RHE_CH01035 1 None None None 86356348 Common aglF alpha-glucoside ABC transporter, permease protein RHE_CH00697 146 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 86359313 Common - putative aldehyde dehydrogenase protein RHE_CH03723 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 86357331 Common - hypothetical protein RHE_CH01701 7 None None None 86358324 Nonpathogen - hypothetical protein RHE_CH02718 1 None None None 86355902 Common - hypothetical protein RHE_CH00244 30 COG3526 COG3526, Uncharacterized protein conserved in bacteria Posttranslational modification, protein turnover, chaperones 86357979 Common - hypothetical protein RHE_CH02364 4 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 86358555 Common recQ ATP-dependent DNA helicase protein RHE_CH02953 232 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 86357281 Common mrcA penicillin binding peptidoglycan synthetase protein RHE_CH01647 200 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 86357777 Common holB DNA polymerase III subunit delta' RHE_CH02159 232 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 86358625 Common prsAch ribose-phosphate pyrophosphokinase RHE_CH03023 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 86355927 Common - hypothetical protein RHE_CH00269 7 None None None 86358296 Common - hypothetical protein RHE_CH02690 17 None None None 86358452 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase RHE_CH02849 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 86357323 Common rpmD 50S ribosomal protein L30 RHE_CH01693 50 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 86356149 Common fucUch2 fucose dissimilation pathway protein RHE_CH00493 33 COG4154 FucU, Fucose dissimilation pathway protein FucU Carbohydrate transport and metabolism 86357814 Common - hypothetical protein RHE_CH02198 9 COG5502 COG5502, Uncharacterized conserved protein Function unknown 86358151 Common - probable transcriptional regulator protein, MarR family RHE_CH02541 109 COG1846 MarR, Transcriptional regulators Transcription 86358012 Common tktA transketolase C-terminal subunit protein RHE_CH02397 229 COG3958 COG3958, Transketolase, C-terminal subunit Carbohydrate transport and metabolism 86359081 Common - probable transcriptional regulator protein, ArsR family RHE_CH03490 37 COG0640 ArsR, Predicted transcriptional regulators Transcription 86356289 Common cheY1 chemotaxis two-component response regulator protein RHE_CH00638 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 86359657 Common - hypothetical protein RHE_CH04079 55 COG2861 COG2861, Uncharacterized protein conserved in bacteria Function unknown 86358063 Common hndJ multidrug ABC transporter, permease protein RHE_CH02451 179 COG1511 COG1511, Predicted membrane protein Function unknown 86357983 Common - probable nitroreductase protein RHE_CH02368 108 COG0778 NfnB, Nitroreductase Energy production and conversion 86356073 Common - hypothetical protein RHE_CH00416 6 None None None 86359494 Common ppa inorganic pyrophosphatase RHE_CH03913 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 86359362 Nonpathogen - hypothetical protein RHE_CH03779 1 None None None 86356076 Common - hypothetical protein RHE_CH00419 105 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 86357202 Common - probable cytochrome-c oxidase protein RHE_CH01565 73 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 86358219 Common - hypothetical protein RHE_CH02612 10 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 86356600 Common ctaB protoheme IX farnesyltransferase RHE_CH00954 197 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 86356772 Common cysN sulfate adenylate transferase subunit 1 protein (cysteine biosynthesis protein) RHE_CH01130 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 86357489 Common - probable acetyltransferase protein RHE_CH01863 26 COG0456 RimI, Acetyltransferases General function prediction only 86356175 Common apaG ApaG RHE_CH00521 89 COG2967 ApaG, Uncharacterized protein affecting Mg2+/Co2+ transport Inorganic ion transport and metabolism 86355727 Common - probable transcriptional regulator protein, LuxR family RHE_CH00066 151 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 86357362 Nonpathogen - hypothetical protein RHE_CH01732 1 None None None 86356467 Common hisS histidyl-tRNA synthetase RHE_CH00821 248 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 86356799 Common - putative sensory box/GGDEF family protein RHE_CH01159 189 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 86356952 Common mgtE magnesium (mg2+) transporter protein RHE_CH01312 171 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 86357853 Nonpathogen - hypothetical protein RHE_CH02238 1 None None None 86357459 Common yajC preprotein tranlocase protein RHE_CH01831 44 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 86359694 Common leuS leucyl-tRNA synthetase RHE_CH04116 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 86355678 Common - probable lytic murein transglycosylase A protein RHE_CH00009 93 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 86356544 Common - probable FAD-dependent oxidoreductase protein RHE_CH00898 200 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 86357172 Common - probable transcriptional regulator protein, MerR family RHE_CH01534 91 COG0789 SoxR, Predicted transcriptional regulators Transcription 86355741 Common - putative oxidoreductase protein RHE_CH00080 91 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 86359518 Common - putative ABC transporter, ATP-binding protein (involved in lysophospholipase L1 biosynthesis) RHE_CH03938 249 COG4181 COG4181, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 86356231 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase RHE_CH00579 208 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 86359178 Common - probable two-component sensor histidine kinase protein RHE_CH03588 215 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 86357937 Common alaS alanyl-tRNA synthetase RHE_CH02322 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 86355989 Common - hypothetical protein RHE_CH00332 8 None None None 86359097 Common rpmE 50S ribosomal protein L31 RHE_CH03506 159 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 86356219 Common - probable two-component sensor histidine kinase/response regulator hybrid protein RHE_CH00566 227 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 86357352 Common - probable NADP-dependent L-sorbosone dehydrogenase protein RHE_CH01722 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 86357517 Common aapM general L-amino acid ABC transporter, permease protein RHE_CH01896 183 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 86356294 Common cheY2 chemotaxis two-component response regulator protein RHE_CH00643 224 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 86359433 Common argI arginase protein RHE_CH03851 109 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 86356310 Common flgC flagellar basal body rod protein FlgC RHE_CH00659 126 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 86358285 Common - putative methyltransferase protein RHE_CH02679 17 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 86358304 Common - hypothetical protein RHE_CH02698 8 None None None 86359427 Common - putative transcriptional regulator protein, LacI family RHE_CH03845 128 COG1609 PurR, Transcriptional regulators Transcription 86355960 Common - hypothetical protein RHE_CH00303 50 COG3488 COG3488, Predicted thiol oxidoreductase Energy production and conversion 86359027 Common - probable oxidoreductase protein RHE_CH03435 99 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 86356138 Common - probable proline/glycine betaine ABC transporter, permease protein RHE_CH00482 124 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 86357854 Common - hypothetical protein RHE_CH02239 85 COG4549 COG4549, Uncharacterized protein conserved in bacteria Function unknown 86358132 Common - hypothetical protein RHE_CH02521 12 COG5569 COG5569, Uncharacterized conserved protein Function unknown 86356007 Common - allantoate amidohydrolase RHE_CH00350 85 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 86357043 Common - hypothetical protein RHE_CH01405 7 None None None 86357780 Common rlpA rare lipoprotein A precursor protein RHE_CH02162 137 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 86356751 Common - putative acyltransferase protein RHE_CH01109 2 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 86355853 Common deoA thymidine phosphorylase RHE_CH00194 135 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 86355920 Common rplT 50S ribosomal protein L20 RHE_CH00262 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 86355717 Common hslU ATP-dependent protease ATP-binding subunit RHE_CH00049 209 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 86359523 Common - hypothetical protein RHE_CH03943 33 COG5429 COG5429, Uncharacterized secreted protein Function unknown 86359577 Common - putative protein require for succinylation of osmoregulated periplasmic glucans RHE_CH03998 33 COG4645 COG4645, Uncharacterized protein conserved in bacteria Function unknown 86359020 Common - probable Di- and tricarboxylate transporter protein RHE_CH03428 125 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 86355757 Common - hypothetical protein RHE_CH00096 2 None None None 86357644 Common cyaH adenylate/guanylate cyclase protein RHE_CH02025 40 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 86357256 Common - hypothetical protein RHE_CH01622 16 COG5454 COG5454, Predicted secreted protein Function unknown 86357573 Common ntrX nitrogen regulation (two-component response regulator) protein RHE_CH01952 226 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 86357665 Common - probable nitrate/sulfonate/bicarbonate ABC transporter, substrate-binding protein RHE_CH02046 77 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 86357085 Common - hypothetical protein RHE_CH01447 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 86358949 Common - probable transcriptional regulator protein, LysR family RHE_CH03351 151 COG0583 LysR, Transcriptional regulator Transcription 86356266 Nonpathogen - probable polysaccharidase protein RHE_CH00615 1 None None None 86357963 Common - probable ABC transporter, ATP-binding protein RHE_CH02348 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 86356214 Common - probable transcriptional regulator protein, MarR family RHE_CH00561 23 COG1846 MarR, Transcriptional regulators Transcription 86356317 Common fliL flagellar biosynthesis transmembrane protein RHE_CH00666 11 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 86356367 Common potH spermidine/putrescine ABC transporter, permease component I protein RHE_CH00716 209 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 86359059 Common sqdB sulfolipid (UDP-sulfoquinovose) biosynthesis protein RHE_CH03468 149 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 86357477 Common - probable transcriptional regulator protein, TetR family RHE_CH01850 5 COG1309 AcrR, Transcriptional regulator Transcription 86358805 Common - hypothetical protein RHE_CH03205 45 COG1944 COG1944, Uncharacterized conserved protein Function unknown 86357263 Common dinP DNA polymerase IV RHE_CH01629 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 86358082 Common - hypothetical protein RHE_CH02470 13 None None None 86358979 Common - probable exopolysaccharide polymerization/export protein RHE_CH03381 110 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 86358601 Nonpathogen - putative glycosyltransferase protein RHE_CH02999 6 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 86359677 Common phoA alkaline phosphatase protein RHE_CH04099 86 COG1785 PhoA, Alkaline phosphatase Inorganic ion transport and metabolism 86357131 Common - hypothetical protein RHE_CH01493 30 COG4222 COG4222, Uncharacterized protein conserved in bacteria Function unknown 86356960 Common - hypothetical conserved membrane protein RHE_CH01320 28 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 86358139 Nonpathogen - hypothetical protein RHE_CH02529 7 None None None 86356886 Common - hypothetical protein RHE_CH01246 12 None None None 86356819 Common - probable ABC transporter, ATP-binding protein RHE_CH01179 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 86356964 Common - hypothetical protein RHE_CH01324 20 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 86357457 Common lppB lipoprotein precursor protein RHE_CH01829 193 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 86356796 Nonpathogen - hypothetical protein RHE_CH01156 2 None None None 86355816 Common - hypothetical protein RHE_CH00156 27 None None None 86356012 Common fpg formamidopyrimidine-DNA glycosylase RHE_CH00355 178 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 86359205 Common - hypothetical protein RHE_CH03615 7 None None None 86358572 Common lpcC lipopolysaccharide core biosynthesis mannosyltransferase protein RHE_CH02970 212 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 86356054 Common - putative acetyltransferase protein RHE_CH00397 16 COG0456 RimI, Acetyltransferases General function prediction only 86356106 Common - hypothetical protein RHE_CH00450 26 COG4782 COG4782, Uncharacterized protein conserved in bacteria Function unknown 86357949 Common folK 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinas e protein RHE_CH02334 203 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 86357544 Common lpxA UDP-N-acetylglucosamine acyltransferase RHE_CH01923 146 COG1043 LpxA, Acyl- acyl carrier protein 86357103 Common - probable amino acid ABC transporter, substrate-binding protein RHE_CH01465 145 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 162329647 Common - hypothetical protein RHE_CH00091 10 COG2900 SlyX, Uncharacterized protein conserved in bacteria Function unknown 86355764 Common - hypothetical protein RHE_CH00104 2 None None None 86356810 Common - hypothetical protein RHE_CH01170 3 None None None 86357605 Nonpathogen - hypothetical protein RHE_CH01985 2 None None None 86358019 Common - short chain dehydrogenase RHE_CH02404 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 86356765 Common - hypothetical protein RHE_CH01123 24 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 86357616 Nonpathogen - hypothetical protein RHE_CH01996 3 None None None 86357684 Common - putative oxidoreductase protein RHE_CH02065 79 COG0431 COG0431, Predicted flavoprotein General function prediction only 86356061 Common rpoNch RNA polymerase factor sigma-54 RHE_CH00404 144 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 86356514 Common rnhB ribonuclease HII RHE_CH00868 207 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 86357250 Common nuoL NADH dehydrogenase subunit L RHE_CH01616 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 86356055 Common - hypothetical protein RHE_CH00398 13 None None None 86359566 Common - hypothetical protein RHE_CH03987 33 COG3812 COG3812, Uncharacterized protein conserved in bacteria Function unknown 86358525 Nonpathogen - hypothetical protein RHE_CH02923 2 None None None 86356982 Common iolD myo-inositol catabolism, acetolactate synthase protein RHE_CH01343 221 COG3962 COG3962, Acetolactate synthase Amino acid transport and metabolism 86356111 Common - probable transcriptional regulator protein, TetR family RHE_CH00455 91 COG1309 AcrR, Transcriptional regulator Transcription 86356863 Common - hypothetical protein RHE_CH01223 110 COG0397 COG0397, Uncharacterized conserved protein Function unknown 86356471 Common gstch3 glutathione S-transferase protein RHE_CH00825 99 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 86358098 Common cobE precorrin-3B C17-methyltransferase protein RHE_CH02486 31 COG2073 CbiG, Cobalamin biosynthesis protein CbiG Coenzyme metabolism 86355941 Common - hypothetical protein RHE_CH00283 116 COG2606 EbsC, Uncharacterized conserved protein Function unknown 86356257 Common dapAch1 dihydrodipicolinate synthase protein RHE_CH00606 234 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 86356498 Common - probable gluconolactonase protein (calcium-binding regucalcin-like) RHE_CH00852 69 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 86355737 Common - probable D-2-hydroxyacid dehydrogenase protein RHE_CH00076 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 86357228 Common - putative permease protein RHE_CH01591 79 None None None 86358706 Common - probable glycosyltransferase protein RHE_CH03105 149 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 86355848 Common - probable sugar ABC transporter, permease protein RHE_CH00189 105 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 86359105 Common suhBch myo-inositol-1(or 4)-monophosphatase protein RHE_CH03514 212 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 86357080 Common fabD [acyl-carrier protein] S-malonyltransferase protein RHE_CH01442 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 86357269 Common - probable ABC transporter, permease protein RHE_CH01635 87 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86357895 Common kptA RNA 2`-phosphotransferase protein RHE_CH02280 43 COG1859 KptA, RNA:NAD 2'-phosphotransferase Translation, ribosomal structure and biogenesis 86356808 Common - hypothetical protein RHE_CH01168 68 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 86358993 Common - probable multicopper oxidase protein RHE_CH03395 26 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 86359674 Common - hypothetical protein RHE_CH04096 27 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 86357428 Common - hypothetical protein RHE_CH01798 13 None None None 86357122 Common - probable anaerobic dehydrogenase protein RHE_CH01484 177 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 86359039 Common - probable branched-chain amino acid ABC transporter, permease protein RHE_CH03447 133 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 86357393 Common - probable transcriptional regulator protein, TetR family RHE_CH01763 67 COG1309 AcrR, Transcriptional regulator Transcription 86357524 Common cysE1 serine acetyltransferase protein RHE_CH01903 210 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 86358269 Common - hypothetical protein RHE_CH02663 27 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 86356060 Common - probable amino acid ABC transporter, ATP-binding protein RHE_CH00403 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 86359444 Common soxR redox-sensitive transcriptional regulator-activator protein RHE_CH03863 82 COG0789 SoxR, Predicted transcriptional regulators Transcription 86358021 Common mobA molybdopterin-guanine dinucleotide biosynthesis protein RHE_CH02406 50 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 86357551 Common kdsA 2-dehydro-3-deoxyphosphooctonate aldolase RHE_CH01930 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 86355878 Common - probable dipeptide ABC transporter, permease protein RHE_CH00219 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 86358053 Common - probable two-component sensor histidine kinase protein RHE_CH02441 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 86356425 Common - probable insertion sequence transposase protein RHE_CH00776 52 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 86359414 Common - probable cobalamin synthesis protein RHE_CH03831 126 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 86359623 Common acd2 acyl-CoA dehydrogenase protein RHE_CH04044 69 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 86358403 Common thyA thymidylate synthase RHE_CH02799 144 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 86357923 Common - putative inositol monophosphatase protein RHE_CH02308 183 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 86357911 Common - hypothetical protein RHE_CH02296 21 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 86358896 Common - probable nitrate/sulfonate ABC transporter, substrate-binding protein RHE_CH03297 94 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 86359291 Common - putative transcriptional regulator protein RHE_CH03701 20 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86357407 Common - probable oxidoreductase protein RHE_CH01777 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 86355930 Common - probable oxidoreductase protein RHE_CH00272 165 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 86357973 Common - probable hydroxypyruvate isomerase protein RHE_CH02358 78 COG3622 Hfi, Hydroxypyruvate isomerase Carbohydrate transport and metabolism 86358025 Common - probable two-component sensor histidine kinase protein RHE_CH02412 217 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 86358465 Common pfk pyrophosphate--fructose-6-phosphate 1-phosphotransferase RHE_CH02862 124 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 86356118 Common - hypothetical protein RHE_CH00462 62 COG3546 COG3546, Mn-containing catalase Inorganic ion transport and metabolism 86357959 Common - probable D-alanyl-D-alanine carboxypeptidase protein RHE_CH02344 157 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 86358714 Common - putative transporter protein RHE_CH03113 83 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86359636 Common sfuB iron(III) ABC transporter, permease protein RHE_CH04057 168 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 86357293 Common rplK 50S ribosomal protein L11 RHE_CH01663 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 86356122 Common frcC fructose ABC transporter, permease protein RHE_CH00466 116 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 86356282 Common secD1 bifunctional preprotein translocase subunit SecD/SecF RHE_CH00631 222 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 86356749 Nonpathogen - hypothetical protein RHE_CH01107 1 None None None 86356201 Common - hypothetical protein RHE_CH00548 37 COG1284 COG1284, Uncharacterized conserved protein Function unknown 86356822 Common - hypothetical protein RHE_CH01182 8 None None None 86358864 Nonpathogen - putative membrane protein, transduces energy to outer membrane receptors RHE_CH03265 1 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 86357413 Common - probable nitrate transporter protein RHE_CH01783 107 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 86356489 Common - hypothetical protein RHE_CH00843 24 None None None 86356959 Common - probable glycosyltransferase protein RHE_CH01319 208 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 86357154 Common - hypothetical protein RHE_CH01516 8 None None None 86357749 Common - hypothetical protein RHE_CH02130 5 None None None 86355684 Common - probable bifunctional 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioatedecarboxylase RHE_CH00016 180 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 86356049 Common lpsA lipoprotein signal peptidase protein RHE_CH00392 200 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 86356933 Common degPch2 serine protease DO-like protein RHE_CH01293 224 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 86358766 Common chvE xylose ABC transporter, substrate-binding protein RHE_CH03165 92 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 86359047 Common - probable heat resistant agglutinin 1 protein RHE_CH03456 21 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 86359284 Common araG L-arabinose transporter ATP-binding protein RHE_CH03694 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 86357093 Common - putative phosphatase protein RHE_CH01455 15 None None None 86357617 Common - hypothetical protein RHE_CH01997 12 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 86357885 Common rpe D-ribulose-5 phosphate 3-epimerase protein RHE_CH02270 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 86356856 Common - probable glutathione S-transferase protein RHE_CH01216 79 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 86359391 Common - putative acetyltransferase protein RHE_CH03808 4 COG0456 RimI, Acetyltransferases General function prediction only 86355958 Common - hypothetical protein RHE_CH00301 24 COG3490 COG3490, Uncharacterized protein conserved in bacteria Function unknown 86356440 Common guaB inositol-5-monophosphate dehydrogenase RHE_CH00794 242 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 86356987 Common ropAch1 porin outer membrane protein RHE_CH01349 13 None None None 86356949 Common - hypothetical protein RHE_CH01309 44 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 86358478 Common - putative lysophospholipase protein RHE_CH02875 83 COG2267 PldB, Lysophospholipase Lipid metabolism 86356279 Common - putative transcriptional regulator protein, LuxR family RHE_CH00628 93 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 86355998 Common - putative glutamine amidotransferase protein RHE_CH00341 79 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 86358676 Common - hypothetical protein RHE_CH03074 3 None None None 86359451 Common atpD F0F1 ATP synthase subunit beta RHE_CH03870 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 86356566 Common matA malonyl-CoA decarboxylase protein RHE_CH00920 29 None None None 86358214 Common - hypothetical protein RHE_CH02607 17 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 86358293 Common - hypothetical protein RHE_CH02687 13 COG3832 COG3832, Uncharacterized conserved protein Function unknown 86359485 Common hemC porphobilinogen deaminase RHE_CH03904 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 86356302 Common fliG flagellar motor switch protein G RHE_CH00651 123 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 86356337 Common flhA flagellar biosynthesis protein A RHE_CH00686 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 86357359 Common - probable oxidoreductase protein RHE_CH01729 180 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 86357994 Common - hypothetical protein RHE_CH02379 12 COG3184 COG3184, Uncharacterized protein conserved in bacteria Function unknown 86357558 Common - putative acetyltransferase protein RHE_CH01937 6 COG0456 RimI, Acetyltransferases General function prediction only 86358372 Common - hypothetical protein RHE_CH02768 76 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 86357823 Common - hypothetical protein RHE_CH02207 12 None None None 86358828 Common prsD protease/lipase ABC transporter, ATP-binding and permease protein RHE_CH03229 249 COG4618 ArpD, ABC-type protease/lipase transport system, ATPase and permease components General function prediction only 86359213 Common - probable transcriptional regulator protein, MarR family RHE_CH03623 101 COG1846 MarR, Transcriptional regulators Transcription 86358587 Nonpathogen - hypothetical protein RHE_CH02985 1 None None None 86357146 Common glyA serine hydroxymethyltransferase RHE_CH01508 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 86356357 Common glnA1 glutamine synthetase protein RHE_CH00706 224 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 86356995 Nonpathogen - hypothetical protein RHE_CH01357 1 None None None 86357166 Common - hypothetical protein RHE_CH01528 31 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 86359168 Common ropAch3 porin outer membrane protein RHE_CH03578 13 None None None 86359376 Common etfAch electron-transport flavoprotein, alpha-subunit RHE_CH03793 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 86356449 Common gsh glutamate-cysteine ligase protein RHE_CH00803 53 COG3572 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 86356048 Common - probable two-component sensor histidine kinase/response regulator hybrid protein RHE_CH00391 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 86356067 Common - hypothetical protein RHE_CH00410 141 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 86356629 Common - probable cytochrome-c oxidase, subunit II protein RHE_CH00983 37 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 86356628 Common - probable cytochrome-c oxidase, subunit I protein RHE_CH00982 164 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 86359544 Common - putative amino acid ABC transporter, permease protein RHE_CH03964 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 86356436 Common - hypothetical protein RHE_CH00790 10 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 86357657 Common - hypothetical protein RHE_CH02038 26 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 86359639 Common - hypothetical protein RHE_CH04060 32 COG5476 COG5476, Uncharacterized conserved protein Function unknown 86359293 Common - short chain dehydrogenase RHE_CH03703 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 86356844 Common - probable phosphatase protein RHE_CH01204 9 COG1409 Icc, Predicted phosphohydrolases General function prediction only 86356697 Nonpathogen - hypothetical protein RHE_CH01053 1 None None None 86357011 Common - probable cobalamin synthesis protein, P47K family RHE_CH01373 126 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 86355670 Common - hypothetical protein RHE_CH00001 112 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 86359402 Common - hypothetical protein RHE_CH03819 21 COG4246 COG4246, Uncharacterized protein conserved in bacteria Function unknown 86357806 Common - probable acetyltransferase protein RHE_CH02190 65 COG0456 RimI, Acetyltransferases General function prediction only 86358783 Nonpathogen - hypothetical protein RHE_CH03183 1 None None None 86359112 Common cheW4 chemotaxis signal transduction protein RHE_CH03521 122 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 86358128 Nonpathogen - hypothetical protein RHE_CH02517 2 None None None 86357759 Common occMch octopine ABC transporter, permease protein RHE_CH02140 172 COG4160 ArtM, ABC-type arginine/histidine transport system, permease component Amino acid transport and metabolism 86358437 Common - probable acetyltransferase protein RHE_CH02834 79 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 86358127 Common - hypothetical protein RHE_CH02516 3 None None None 86358504 Common metH B12-dependent methionine synthase RHE_CH02901 177 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 86359241 Common - probable multidrug efflux transporter, permease protein RHE_CH03651 197 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86359088 Nonpathogen - hypothetical protein RHE_CH03497 3 None None None 86357869 Common nifSch pyridoxal-phosphate-dependent aminotransferase protein (nitrogenase cofactor synthesis protein) RHE_CH02254 234 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 86359555 Common tesB acyl-CoA thioesterase II protein RHE_CH03975 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 86358103 Common cobU adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase RHE_CH02491 129 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 86357674 Common - probable sugar ABC transporter, permease protein RHE_CH02055 144 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 86358265 Common - probable sugar ABC transporter, permease protein RHE_CH02659 145 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 86358664 Common - putative hydrolase protein, MutT/nudix family RHE_CH03062 44 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 86358204 Common - probable transcriptional regulator protein, AraC family RHE_CH02597 108 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 86359632 Common - hypothetical protein RHE_CH04053 23 COG5383 COG5383, Uncharacterized protein conserved in bacteria Function unknown 86356833 Common - probable multidrug resistance efflux system protein RHE_CH01193 203 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86357005 Common - probable UDP-glucose 4-epimerase protein RHE_CH01367 231 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 86359252 Nonpathogen - probable spermidine/putrescine ABC transporter, permease protein RHE_CH03662 1 None None None 86357492 Common - hypothetical protein RHE_CH01866 28 COG4765 COG4765, Uncharacterized protein conserved in bacteria Function unknown 86358499 Common - probable sugar ABC transporter, permease protein RHE_CH02896 147 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 86356572 Nonpathogen - hypothetical protein RHE_CH00926 1 None None None 86358812 Common pssS glycosyltransferase protein RHE_CH03213 201 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 86357589 Common - putative peptidase protein (caspase-1 like protein) RHE_CH01969 32 COG4249 COG4249, Uncharacterized protein containing caspase domain General function prediction only 86356538 Common cfa cyclopropane-fatty-acyl-phospholipid synthase protein RHE_CH00892 126 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 86355739 Common - putative endonuclease protein RHE_CH00078 27 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 86357018 Common - probable murein transglycosylase protein RHE_CH01380 139 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 86356298 Common - probable transcriptional regulator protein, LuxR family RHE_CH00647 78 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 86357647 Common - probable saccharide ABC transporter, ATP-binding protein RHE_CH02028 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 86358427 Common - hypothetical protein RHE_CH02824 23 COG5460 COG5460, Uncharacterized conserved protein Function unknown 86355889 Nonpathogen - hypothetical protein RHE_CH00230 1 None None None 86356984 Common - putative transcriptional regulator protein RHE_CH01345 57 COG1737 RpiR, Transcriptional regulators Transcription 86358752 Common - putative DNA alkylation repair protein RHE_CH03151 35 COG4335 COG4335, DNA alkylation repair enzyme DNA replication, recombination, and repair 86355914 Common - hypothetical protein RHE_CH00256 42 COG2346 COG2346, Truncated hemoglobins General function prediction only 86357377 Common - probable aromatic amino acid degradation protein, fumarylacetoacetate hydrolase family RHE_CH01747 81 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 86359469 Common kgd alpha-ketoglutarate decarboxylase RHE_CH03888 148 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 86356335 Common flgD flagellar basal body rod modification protein RHE_CH00684 50 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 86358356 Common ugpAch1 sn-glycerol-3-phosphate ABC transporter, permease protein RHE_CH02751 142 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 86357842 Common adhCch formaldehyde dehydrogenase (glutathione)/alcohol dehydrogenase protein RHE_CH02227 208 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 86357211 Common - putative transporter, permease protein RHE_CH01574 54 None None None 86357738 Nonpathogen - hypothetical protein RHE_CH02119 10 None None None 86358317 Common znuC zinc uptake ABC transporter, ATP-binding protein RHE_CH02711 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 86359233 Common - hypothetical protein RHE_CH03643 55 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 86359226 Common - hypothetical protein RHE_CH03636 48 COG2954 COG2954, Uncharacterized protein conserved in bacteria Function unknown 86359610 Common - putative ABC transporter, ATP-binding protein RHE_CH04031 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 86358873 Common - hypothetical protein RHE_CH03274 5 None None None 86357955 Common - hypothetical protein RHE_CH02340 148 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 86358218 Common - probable transcriptional regulator protein, AraC family RHE_CH02611 88 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 86356148 Common - probable sugar ABC transporter, substrate-binding protein RHE_CH00492 102 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86356632 Common - probable hydrolase phosphatase protein RHE_CH00986 132 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 86356725 Nonpathogen ndiA1 nutrient deprivation-induced protein RHE_CH01082 4 None None None 86356088 Common - putative transforming growth factor-induced protein (and secreted protein MPB70) RHE_CH00431 69 COG2335 COG2335, Secreted and surface protein containing fasciclin-like repeats Cell envelope biogenesis, outer membrane 86356664 Common - probable transcriptional regulator protein, TetR family RHE_CH01019 14 COG1309 AcrR, Transcriptional regulator Transcription 86359470 Common sucD succinyl-CoA synthetase subunit alpha RHE_CH03889 212 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 86355903 Common - putative glutamine amidotransferase protein RHE_CH00245 136 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 86356942 Common - probable DNA polymerase bacteriophage-type (uracil-DNA glycosylase) protein RHE_CH01302 152 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 86357200 Common - hypothetical protein RHE_CH01563 11 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 86359683 Common - putative NAD-specific glutamate dehydrogenase protein RHE_CH04105 77 COG2902 COG2902, NAD-specific glutamate dehydrogenase Amino acid transport and metabolism 86358819 Common pssH glycosyltransferase protein RHE_CH03220 92 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 86359364 Nonpathogen - hypothetical protein RHE_CH03781 2 None None None 86357743 Common afuC1 iron(III) ABC transporter, ATP-binding protein RHE_CH02124 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 86359487 Common - hypothetical protein RHE_CH03906 16 COG4223 COG4223, Uncharacterized protein conserved in bacteria Function unknown 86357275 Common - dihydroorotase RHE_CH01641 209 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 86355857 Common deoB phosphopentomutase RHE_CH00198 70 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 86355993 Common - hypothetical protein RHE_CH00336 10 None None None 86358559 Common carA carbamoyl phosphate synthase small subunit RHE_CH02957 233 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 86358185 Common - probable two-component sensor histidine kinase protein RHE_CH02576 215 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 86357614 Common - hypothetical protein RHE_CH01994 14 None None None 86357050 Common - probable transcriptional regulator protein, ArsR family RHE_CH01412 116 COG0640 ArsR, Predicted transcriptional regulators Transcription 86356763 Common - probable transcriptional regulator protein RHE_CH01121 126 COG1609 PurR, Transcriptional regulators Transcription 86357602 Common - putative permease protein RHE_CH01982 62 None None None 86358867 Common hmuS hemin transport system, degrading protein RHE_CH03268 40 COG3720 HemS, Putative heme degradation protein Inorganic ion transport and metabolism 86356090 Common - hypothetical protein RHE_CH00433 4 None None None 86358416 Common - probable protein secretion protein, HlyD family RHE_CH02813 171 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 86356096 Common rpmH 50S ribosomal protein L34 RHE_CH00439 190 None None None 86358695 Common adeC1 adenine deaminase protein RHE_CH03094 74 COG1001 AdeC, Adenine deaminase Nucleotide transport and metabolism 86358622 Common - hypothetical protein RHE_CH03020 181 COG1496 COG1496, Uncharacterized conserved protein Function unknown 86356742 Common - hypothetical protein RHE_CH01099 4 None None None 86357021 Common - hypothetical protein RHE_CH01383 63 COG1432 COG1432, Uncharacterized conserved protein Function unknown 86359559 Common trxA2 thioredoxin protein RHE_CH03979 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 86356494 Common mutL DNA mismatch repair protein RHE_CH00848 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 86358288 Common - probable ferrichrome ABC transporter, permease protein RHE_CH02682 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 86357763 Common occT octopine ABC transporter, substrate-binding protein RHE_CH02144 160 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 86357376 Common hmgA homogentisate 1,2-dioxygenase RHE_CH01746 52 COG3508 HmgA, Homogentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 86357671 Common - probable transcriptional regulator protein, ROK family RHE_CH02052 128 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 86357727 Common ssb single-strand DNA-binding protein RHE_CH02108 204 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 86359412 Common - hypothetical protein RHE_CH03829 47 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 86357841 Common pccA propionyl-CoA carboxylase alpha chain protein RHE_CH02226 237 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 86358584 Common - probable sugar ABC transporter, substrate-binding protein RHE_CH02982 72 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86358658 Common - probable insertion sequence transposase protein RHE_CH03056 59 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 86359070 Common - putative regulator protein of stationary/sporulation gene expression RHE_CH03479 8 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 86359407 Common - putative hemolysin protein RHE_CH03824 219 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 162329632 Common leuA2 2-isopropylmalate synthase RHE_CH03067 210 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 86359357 Common - probable acetyl-CoA synthetase protein RHE_CH03773 220 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 86358307 Common - probable fumarylpyruvate hydrolase protein RHE_CH02701 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 86357313 Common rpmC 50S ribosomal protein L29 RHE_CH01683 127 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 86355782 Common - probable transglycosylase protein RHE_CH00122 103 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 86357435 Nonpathogen - hypothetical protein RHE_CH01806 1 None None None 86357150 Common - probable glucose-1-phosphate thymidylyltransferase protein RHE_CH01512 232 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 86358277 Common - hypothetical protein RHE_CH02671 16 None None None 86356483 Common - hypothetical protein RHE_CH00837 97 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 86358337 Common - hypothetical protein RHE_CH02732 2 COG3668 ParE, Plasmid stabilization system protein General function prediction only 86356373 Common - probable metallopeptidase protein RHE_CH00723 25 None None None 86356595 Common - probable acetyltransferase protein RHE_CH00949 49 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 86357466 Nonpathogen - hypothetical protein RHE_CH01838 1 None None None 86356525 Common sohB protease protein RHE_CH00879 172 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 86358775 Common xylG xylose ABC transporter, ATP-binding protein RHE_CH03174 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 86359511 Common - hypothetical protein RHE_CH03931 24 None None None 86355778 Common nusA transcription elongation factor NusA RHE_CH00118 221 COG0195 NusA, Transcription elongation factor Transcription 86356001 Common - probable transcriptional regulator protein, LysR family RHE_CH00344 125 COG0583 LysR, Transcriptional regulator Transcription 86358909 Common ureA urease subunit gamma RHE_CH03310 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 86358108 Common - hypothetical protein RHE_CH02496 2 None None None 86358241 Common - putative RTX toxin hemolysin-type protein RHE_CH02634 43 None None None 86357593 Nonpathogen - hypothetical protein RHE_CH01973 1 None None None 86357834 Common - probable magnesium transporter protein RHE_CH02218 171 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 86359430 Common - putative outer membrane protein, protective antigen RHE_CH03848 142 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 86357179 Nonpathogen - hypothetical protein RHE_CH01541 1 None None None 86357341 Common - probable dehydrogenase protein RHE_CH01711 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 86358192 Nonpathogen - hypothetical protein RHE_CH02584 1 None None None 86356155 Nonpathogen - hypothetical protein RHE_CH00499 1 None None None 86356579 Common - putative transcriptional regulator protein, LysR family RHE_CH00933 108 COG0583 LysR, Transcriptional regulator Transcription 86357829 Common - hypothetical protein RHE_CH02213 31 COG5458 COG5458, Uncharacterized conserved protein Function unknown 86359595 Nonpathogen - hypothetical protein RHE_CH04016 12 None None None 86356681 Common - putative transcriptional regulator protein, LuxR family RHE_CH01037 99 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 86357883 Common - probable 4-hydroxyphenylacetate 3-monooxygenase small chain protein RHE_CH02268 111 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 86356713 Nonpathogen - hypothetical protein RHE_CH01070 5 None None None 86358577 Common trxBch thioredoxin reductase (NADPH) protein RHE_CH02975 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 86356395 Common rpoE1 RNA polymerase sigma factor protein (sigma-24) RHE_CH00746 155 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 86357891 Common - hypothetical protein RHE_CH02276 56 COG3545 COG3545, Predicted esterase of the alpha/beta hydrolase fold General function prediction only 86357046 Common - hypothetical protein RHE_CH01408 80 COG1742 COG1742, Uncharacterized conserved protein Function unknown 86357230 Common - probable oxidoreductase protein RHE_CH01593 192 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 86357773 Common - probable metal-dependent hydrolase protein RHE_CH02155 72 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 86358661 Common - putative acetyltransferase protein RHE_CH03059 28 COG3393 COG3393, Predicted acetyltransferase General function prediction only 86359584 Common - probable amino acid ABC transporter, permease protein RHE_CH04005 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 86355891 Common - hypothetical protein RHE_CH00232 41 COG4748 COG4748, Uncharacterized conserved protein Function unknown 86356133 Common pgi glucose-6-phosphate isomerase RHE_CH00477 199 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 86356166 Common pstB phosphate ABC transporter, ATP-binding protein RHE_CH00512 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 86357409 Common - putative hydrolase protein, haloacid dehalogenase-like family RHE_CH01779 53 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 86359064 Common - hypothetical protein RHE_CH03473 29 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 86355807 Common - hypothetical protein RHE_CH00147 15 COG4991 COG4991, Uncharacterized protein with a bacterial SH3 domain homologue Function unknown 86356876 Common - hypothetical protein RHE_CH01236 89 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 86356185 Common mcpAch methyl-accepting chemotaxis protein RHE_CH00532 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 86356384 Common rirA iron-responsive transcriptional regulator RHE_CH00735 166 COG1959 COG1959, Predicted transcriptional regulator Transcription 86358759 Common - putative transglutaminase protein RHE_CH03158 108 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 86356686 Common - probable two-component sensor histidine kinase protein RHE_CH01042 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 86358848 Common - probable transcriptional regulator protein, TetR family RHE_CH03249 59 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 86359185 Common glgC glucose-1-phosphate adenylyltransferase RHE_CH03595 168 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 86358768 Common - hypothetical protein RHE_CH03167 3 None None None 162329645 Common purN phosphoribosylglycinamide formyltransferase RHE_CH01487 221 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 86358406 Common - hypothetical protein RHE_CH02802 27 COG4321 COG4321, Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis General function prediction only 86359702 Common rho transcription termination factor Rho RHE_CH04124 211 COG1158 Rho, Transcription termination factor Transcription 86355866 Common cpaE pilus assembly protein, response regulator protein RHE_CH00207 74 COG4963 CpaE, Flp pilus assembly protein, ATPase CpaE Intracellular trafficking and secretion 86358438 Common ligA NAD-dependent DNA ligase LigA RHE_CH02835 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 86357237 Common nuoB1 NADH dehydrogenase subunit B RHE_CH01603 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 86358038 Common - probable transcriptional regulator protein, ArsR family RHE_CH02425 49 COG0640 ArsR, Predicted transcriptional regulators Transcription 86358564 Common - probable multidrug efflux protein RHE_CH02962 181 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 86358638 Common fbcC ubiquinol--cytochrome c reductase, cytochrome c1 subunit protein RHE_CH03036 73 COG2857 CYT1, Cytochrome c1 Energy production and conversion 86359664 Common - hypothetical protein RHE_CH04086 50 COG3824 COG3824, Uncharacterized protein conserved in bacteria Function unknown 86358736 Common - probable CDP-alcohol phosphatidyltransferase protein RHE_CH03135 24 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 86358145 Common arsH arsenical resistance protein RHE_CH02535 69 COG0431 COG0431, Predicted flavoprotein General function prediction only 86358391 Common - probable amino acid efflux protein, LysE family RHE_CH02787 73 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 86357820 Common - putative inosine-5`-monophosphate dehydrogenase protein RHE_CH02204 177 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 86357532 Common - putative translation initiation inhibitor protein RHE_CH01911 96 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 86359163 Common pldB lysophospholipase L2 protein RHE_CH03572 82 COG2267 PldB, Lysophospholipase Lipid metabolism 86359174 Common - hypothetical protein RHE_CH03584 74 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 86357950 Common folB dihydroneopterin aldolase protein RHE_CH02335 76 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 86355836 Common - probable peptide ABC transporter, permease protein RHE_CH00176 219 COG4174 COG4174, ABC-type uncharacterized transport system, permease component General function prediction only 86358165 Common - putative two-component response regulator protein RHE_CH02556 62 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 86355690 Common trpA tryptophan synthase subunit alpha RHE_CH00022 217 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 86356274 Common - hypothetical protein RHE_CH00623 37 COG0400 COG0400, Predicted esterase General function prediction only 86358680 Nonpathogen - hypothetical protein RHE_CH03079 8 COG3904 COG3904, Predicted periplasmic protein Function unknown 86359442 Common - probable transcriptional regulator protein, ArsR family RHE_CH03861 152 COG0640 ArsR, Predicted transcriptional regulators Transcription 86359419 Nonpathogen - hypothetical protein RHE_CH03837 2 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 86358281 Common - probable alkanal monooxygenase (bacterial liciferase alpha chain) like protein RHE_CH02675 72 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 86358537 Common - hypothetical conserved membrane protein RHE_CH02935 88 COG2968 COG2968, Uncharacterized conserved protein Function unknown 86356898 Nonpathogen - hypothetical protein RHE_CH01258 1 None None None 86357582 Common - hypothetical protein RHE_CH01961 54 COG3749 COG3749, Uncharacterized protein conserved in bacteria Function unknown 86357386 Common cinA1 competence-damage associated protein (nucleotide-utilizing enzyme related tomolybdopterin-biosynthesis enzyme MoeA) RHE_CH01756 165 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 86357577 Common mazG nucleoside triphosphate pyrophosphohydrolase RHE_CH01956 156 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 86358932 Common ctrA two-component response regulator protein controls chromosomal replication initiation RHE_CH03334 214 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 86358546 Common - hypothetical protein RHE_CH02944 41 COG3382 COG3382, Uncharacterized conserved protein Function unknown 86359600 Nonpathogen - hypothetical protein RHE_CH04021 1 COG4803 COG4803, Predicted membrane protein Function unknown 86358455 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase RHE_CH02852 211 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 86359422 Common - putative sugar ABC transporter, ATP-binding protein RHE_CH03840 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 86358877 Common - dihydropyrimidine dehydrogenase RHE_CH03278 128 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 86358644 Common - probable ABC transporter, ATP-binding protein RHE_CH03042 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 86359304 Common cyaG2 adenylate cyclase protein RHE_CH03714 81 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 86359473 Common - putative ATP-binding protein RHE_CH03892 95 COG1485 COG1485, Predicted ATPase General function prediction only 86357026 Common acpS 4'-phosphopantetheinyl transferase RHE_CH01388 143 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 86357563 Common - putative DNA topology modulation kinase FlaR-like protein RHE_CH01942 42 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 86355871 Common - putative pilus assembly protein (contains TPR repeats) RHE_CH00212 29 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 86358858 Common - putative globin-like protein RHE_CH03259 65 COG2346 COG2346, Truncated hemoglobins General function prediction only 86356247 Common - hypothetical protein RHE_CH00596 35 COG3219 COG3219, Uncharacterized protein conserved in bacteria Function unknown 86358015 Common rbsBch3 ribose ABC transporter, substrate-binding protein RHE_CH02400 95 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86355880 Common - probable dipeptide ABC transporter, substrate-binding protein RHE_CH00221 207 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 86358829 Common plyA3 polysaccharidase protein RHE_CH03230 22 None None None 86358959 Common mexF2 multidrug-efflux system, acriflavin resistance protein RHE_CH03361 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 86356701 Common - hypothetical protein RHE_CH01057 25 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 86357308 Common rplB 50S ribosomal protein L2 RHE_CH01678 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 86357400 Common aldA alanine dehydrogenase protein RHE_CH01770 164 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 86358687 Common proW proline/glycine betaine ABC transporter, permease protein RHE_CH03086 195 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 86357687 Common - probable sugar ABC transporter, substrate-binding protein RHE_CH02068 23 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86357186 Common - probable 3-demethylubiquinone-9 3-methyltransferase protein RHE_CH01549 156 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 86359037 Common - putative branched-chain amino acid ABC transporter, substrate-binding protein RHE_CH03445 137 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 86356584 Common fabI2 enoyl-(acyl carrier protein) reductase RHE_CH00938 233 COG0623 FabI, Enoyl- acyl-carrier-protein 86357346 Common - putative two-component sensor histidine kinase protein RHE_CH01716 178 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 86357519 Common aapJ general L-amino acid ABC transporter, substrate-binding protein RHE_CH01898 120 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 86356413 Common exoU UDP-hexose transferase protein RHE_CH00764 162 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 86356972 Common - probable insertion sequence transposase protein, IS10 RHE_CH01332 19 None None None 86356208 Common - putative hemagglutinin protein RHE_CH00555 101 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 86355898 Common - probable insertion sequence transposase protein RHE_CH00239 67 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 86356643 Common mutY A/G-specific adenine glycosylase protein RHE_CH00997 221 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 86358487 Common - probable alcohol dehydrogenase protein RHE_CH02884 173 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 86358945 Common - dihydroxy-acid dehydratase RHE_CH03347 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 86357481 Common gatC glutamyl-tRNA amidotransferase subunit C protein RHE_CH01854 148 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 86356913 Common - probable serine protease protein RHE_CH01273 193 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 86358900 Common ureF urease accessory protein RHE_CH03301 64 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 86358608 Common - hypothetical protein RHE_CH03006 10 None None None 86359437 Common fdsC formate dehydrogenase accessory protein RHE_CH03856 137 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 86358589 Common - probable sugar ABC transporter, ATP-binding protein RHE_CH02987 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 86358960 Common - probable serine/threonine specific protein phosphatase protein RHE_CH03362 81 None None None 86356255 Common appF oligopeptide ABC transporter, ATP-binding protein RHE_CH00604 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 86357680 Common dppBch2 dipeptide ABC transporter, permease protein RHE_CH02061 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 86356556 Common - probable RNA-methyltransferase protein RHE_CH00910 191 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 86358302 Common cyaK adenylate cyclase protein RHE_CH02696 90 COG4252 COG4252, Predicted transmembrane sensor domain Signal transduction mechanisms 86356292 Common cheRch1 chemotaxis methyltransferase protein RHE_CH00641 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 86356722 Common - probable transcriptional regulator protein, ArsR family RHE_CH01079 107 COG0640 ArsR, Predicted transcriptional regulators Transcription 86356783 Common - probable quinone oxidoreductase protein RHE_CH01141 194 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 86358094 Common cobC pyridoxal-phosphate-dependent aminotransferase protein (cobalamin biosynthesis protein) RHE_CH02482 203 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 86356238 Common - zinc-binding protein RHE_CH00586 36 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 86356369 Common - hypothetical conserved membrane protein RHE_CH00718 18 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 86358967 Common ugpCch2 sn-glycerol-3-phosphate ABC transporter, ATP-binding protein RHE_CH03369 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 86358175 Common - hypothetical protein RHE_CH02566 109 COG2135 COG2135, Uncharacterized conserved protein Function unknown 86357946 Common - hypothetical protein RHE_CH02331 42 COG3106 COG3106, Predicted ATPase General function prediction only 86356190 Common - probable two-component response regulator protein RHE_CH00537 173 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 86357904 Common aroQ2 3-dehydroquinate dehydratase RHE_CH02289 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 86359003 Common - probable protein secretion protein, HlyD family RHE_CH03411 166 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 86356242 Common - probable arylamine N-acetyltransferase protein RHE_CH00591 35 COG2162 NhoA, Arylamine N-acetyltransferase Secondary metabolites biosynthesis, transport, and catabolism 86359573 Common dppCch3 dipeptide ABC transporter, permease protein RHE_CH03994 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 86358476 Common - putative ABC transporter ATP-binding protein RHE_CH02873 247 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 86359025 Common - probable two-component response regulator protein RHE_CH03433 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 86359525 Common ccmA heme ABC transporter, ATP-binding protein (involved in cytochrome-c biogenesis) RHE_CH03945 249 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 86355719 Common - probable cytochrome p450 protein RHE_CH00051 76 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 86358017 Common - short chain dehydrogenase RHE_CH02402 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 86358230 Common - probable lactoylglutathione lyase protein RHE_CH02623 50 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 86356264 Common rbsAch1 ribose ABC transporter, ATP-binding protein RHE_CH00613 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 86357245 Common nuoG1 NADH dehydrogenase subunit G RHE_CH01611 191 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 86356974 Nonpathogen - hypothetical protein RHE_CH01334 1 None None None 86357174 Common - putative two-component sensor histidine kinase protein RHE_CH01536 213 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 86357913 Common - probable catechol 1,2-dioxygenase protein RHE_CH02298 47 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 86359429 Nonpathogen - hypothetical protein RHE_CH03847 1 None None None 86358693 Nonpathogen - hypothetical protein RHE_CH03092 1 None None None 86359500 Nonpathogen - hypothetical protein RHE_CH03919 5 None None None 86359321 Common - putative monovalent cation/H+ antiporter subunit D RHE_CH03731 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 86356233 Common hisD histidinol dehydrogenase RHE_CH00581 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 86358134 Nonpathogen - hypothetical protein RHE_CH02524 1 None None None 86357455 Common surE stationary phase survival protein SurE RHE_CH01827 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 86355855 Common upp uracil phosphoribosyltransferase RHE_CH00196 165 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 86358639 Common fbcB ubiquinol-cytochrome-c reductase, cytochrome b subunit protein RHE_CH03037 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 86359692 Common - probable propionate-CoA ligase protein RHE_CH04114 219 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 86356753 Nonpathogen - hypothetical protein RHE_CH01111 1 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 86357437 Common pcm1 protein-L-isoaspartate O-methyltransferase protein RHE_CH01809 153 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 86356930 Common cycJ cytochrome c-type biogenesis protein CcmE RHE_CH01290 92 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 86356071 Common fmt methionyl-tRNA formyltransferase RHE_CH00414 215 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 86359334 Common - probable NADH-ubiquinone oxidoreductase protein RHE_CH03744 189 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 86357350 Common - probable acyl-CoA transferase protein RHE_CH01720 86 COG4670 COG4670, Acyl CoA:acetate/3-ketoacid CoA transferase Lipid metabolism 86358347 Nonpathogen - hypothetical protein RHE_CH02742 21 COG1035 FrhB, Coenzyme F420-reducing hydrogenase, beta subunit Energy production and conversion 86359679 Common - putative membrane-bound lytic murein transglycosylase protein RHE_CH04101 100 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 86359008 Common potB spermidine/putrescine ABC transporter, permease component I protein RHE_CH03416 191 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 86355873 Common - probable insertion sequence transposase protein, ISRM11/ISRM2011-2 RHE_CH00214 21 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 86355759 Common cmk cytidylate kinase RHE_CH00098 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 86358450 Common murG N-acetylglucosaminyl transferase RHE_CH02847 208 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 86357368 Common - hypothetical protein RHE_CH01738 4 None None None 86359387 Common - hypothetical protein RHE_CH03804 31 COG1434 COG1434, Uncharacterized conserved protein Function unknown 86358574 Common dctB two-component sensor histidine kinase protein regulating C4-dicarboxylate transport system RHE_CH02972 223 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 86356503 Common - probable transcriptional regulator protein, LuxR family RHE_CH00857 86 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 86357105 Common - putative polysaccharide deacetylase protein RHE_CH01467 102 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 86359281 Common - short chain dehydrogenase RHE_CH03691 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 86359398 Common - hypothetical protein RHE_CH03815 15 None None None 86358724 Common bdhA D-beta-hydroxybutyrate dehydrogenase protein RHE_CH03123 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 86357114 Common moaE molybdopterin converting factor subunit 2 protein RHE_CH01476 150 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 86357851 Common rluC pseudouridylate synthase, ribosomal large subunit C protein RHE_CH02236 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 86357475 Common radC DNA repair protein RadC RHE_CH01848 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 86356745 Common - hypothetical protein RHE_CH01103 8 None None None 86357542 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase RHE_CH01921 164 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 86359146 Common - probable 5`-nucleotidase protein RHE_CH03555 143 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 86357646 Common - probable threonine dehydratase protein RHE_CH02027 228 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 86359648 Common nadD nicotinic acid mononucleotide adenyltransferase RHE_CH04070 175 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 86356935 Common ragB two-component sensor histidine kinase protein RHE_CH01295 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 86357505 Common recJ single-stranded-DNA-specific exonuclease protein RHE_CH01879 193 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 86355933 Nonpathogen - hypothetical protein RHE_CH00275 6 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 86357187 Nonpathogen - hypothetical protein RHE_CH01550 1 None None None 86357935 Common gstch8 glutathione S-transferase protein RHE_CH02320 88 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 86357603 Nonpathogen - hypothetical protein RHE_CH01983 1 None None None 86358248 Common mocBch1 rhizopine ABC transporter, substrate-binding protein RHE_CH02642 99 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86357668 Common - hypothetical protein RHE_CH02049 17 None None None 86355907 Common - probable transcriptional activator (regulator) protein, TenA family RHE_CH00249 77 COG0819 TenA, Putative transcription activator Transcription 86356100 Nonpathogen - hypothetical protein RHE_CH00444 1 None None None 86356390 Common gntK gluconokinase protein RHE_CH00741 80 COG3265 GntK, Gluconate kinase Carbohydrate transport and metabolism 86359071 Common - putative nucleic acid-binding protein RHE_CH03480 16 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 86357116 Common pgsAch CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase protein RHE_CH01478 203 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 86357620 Nonpathogen - hypothetical protein RHE_CH02000 1 None None None 86356993 Common exoQ exopolysaccharide production protein RHE_CH01355 30 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 86357129 Common ppk polyphosphate kinase RHE_CH01491 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 86359609 Common - hypothetical protein RHE_CH04030 26 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 86356781 Common - hypothetical protein RHE_CH01139 36 COG3247 HdeD, Uncharacterized conserved protein Function unknown 86359344 Common - hypothetical protein RHE_CH03760 47 COG5319 COG5319, Uncharacterized protein conserved in bacteria Function unknown 86359263 Common - putative glyoxalase/bleomycin resistance-like protein RHE_CH03673 27 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 86355952 Common - putative reductase protein RHE_CH00295 46 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 86357811 Common - hypothetical protein RHE_CH02195 13 None None None 86358274 Common - putative two-component sensor histidine kinase protein RHE_CH02668 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 86356770 Nonpathogen - hypothetical protein RHE_CH01128 6 None None None 86359126 Common - probable lactone-specific esterase protein RHE_CH03535 91 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 86356126 Common - hypothetical protein RHE_CH00470 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 86357706 Common - probable sugar ABC transporter, permease protein RHE_CH02087 112 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 86358412 Common - hypothetical protein RHE_CH02809 15 COG4954 COG4954, Uncharacterized protein conserved in bacteria Function unknown 86358974 Common - probable sugar ABC transporter, permease protein RHE_CH03376 155 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 86357794 Common moeA molybdopterin biosynthesis protein RHE_CH02177 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 86355710 Common hisF imidazole glycerol phosphate synthase subunit HisF RHE_CH00042 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 86356397 Common - probable glycosyltransferase protein RHE_CH00748 201 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 86357383 Common nrd ribonucleotide-diphosphate reductase subunit alpha RHE_CH01753 191 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 86356206 Common - hypothetical protein RHE_CH00553 28 None None None 86355821 Common - probable acetyltransferase protein RHE_CH00161 67 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 86358049 Common ropAch2 porin outer membrane protein RHE_CH02437 13 None None None 86356593 Common - probable phosphate transporter (pit) regulator protein RHE_CH00947 69 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 86359354 Common secA preprotein translocase subunit SecA RHE_CH03770 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 86357070 Common alr alanine racemase protein RHE_CH01432 198 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 86355695 Common - hypothetical protein RHE_CH00027 51 COG3893 COG3893, Inactivated superfamily I helicase DNA replication, recombination, and repair 86356173 Common - probable insertion sequence transposase protein RHE_CH00519 21 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 86358153 Common cyaCch adenylate cyclase protein RHE_CH02543 14 None None None 86358891 Common dht dihydropyrimidinase RHE_CH03292 206 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 86355785 Common - hypothetical protein RHE_CH00125 170 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 86358623 Common - probable Xaa-Pro dipeptidase protein RHE_CH03021 94 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 86357700 Common - probable sugar ABC transporter, ATP-binding protein RHE_CH02081 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 86357333 Common - putative sulfite oxidase subunit YedY RHE_CH01703 121 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 86357816 Common nifUch2 nitrogen fixation protein RHE_CH02200 65 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 86359554 Common glnK nitrogen regulatory protein P-II RHE_CH03974 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 86357426 Common - hypothetical conserved membrane protein RHE_CH01796 26 COG5478 COG5478, Predicted small integral membrane protein Function unknown 86359083 Common - putative UDP-glucose 4-epimerase protein RHE_CH03492 178 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 86356649 Common ppdK pyruvate phosphate dikinase RHE_CH01003 234 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 86356360 Common mcpZch2 methyl-accepting chemotaxis protein RHE_CH00709 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 86355925 Common - probable transcriptional regulator protein, LysR family RHE_CH00267 140 COG0583 LysR, Transcriptional regulator Transcription 86357360 Common - putative oxidoreductase protein RHE_CH01730 69 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 86357965 Common - probable muconate cycloisomerase I protein RHE_CH02350 120 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 86358326 Common - putative NTP pyrophosphohydrolase protein, MuT/nudix family RHE_CH02721 12 None None None 86357622 Common - putative plasmid stabilization protein RHE_CH02002 136 COG1475 Spo0J, Predicted transcriptional regulators Transcription 86358484 Common - hypothetical protein RHE_CH02881 9 None None None 86357321 Common rplR 50S ribosomal protein L18 RHE_CH01691 216 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 86356640 Common - hypothetical protein RHE_CH00994 31 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 86357753 Common - probable transcriptional regulator protein, MarR family RHE_CH02134 31 COG1846 MarR, Transcriptional regulators Transcription 86358557 Common - hypothetical protein RHE_CH02955 5 None None None 86356177 Nonpathogen - hypothetical protein RHE_CH00523 1 None None None 86359496 Common typA GTP-binding elongation factor protein (tyrosin phosphorylated protein) RHE_CH03915 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 86355720 Common glcB malate synthase G RHE_CH00052 82 COG2225 AceB, Malate synthase Energy production and conversion 86356779 Common betB betaine aldehyde dehydrogenase RHE_CH01137 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 86356947 Common - probable 3-oxoacyl-[acyl-carrier-protein] reductase protein RHE_CH01307 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 86358817 Common pssJ galactosyltransferase protein RHE_CH03218 5 None None None 86359516 Common ligT 2`-5` RNA ligase protein RHE_CH03936 125 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 86356124 Common frcK putative fructose transport system kinase RHE_CH00468 75 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 86356854 Common cycF cytochrome-c-556 signal peptide protein RHE_CH01214 14 COG3909 COG3909, Cytochrome c556 Energy production and conversion 86356328 Common - hypothetical protein RHE_CH00677 44 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 86356859 Common - probable cation efflux system protein RHE_CH01219 138 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 86358512 Common - probable spermidine/putrescine ABC transporter, ATP-binding protein RHE_CH02909 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 86358035 Nonpathogen - hypothetical conserved membrane protein RHE_CH02422 11 COG5530 COG5530, Predicted integral membrane protein Function unknown 86359315 Common - hypothetical protein RHE_CH03725 146 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 86356283 Nonpathogen - hypothetical protein RHE_CH00632 1 None None None 86356824 Nonpathogen - hypothetical protein RHE_CH01184 1 None None None 86358678 Common - probable outer membrane iron receptor protein RHE_CH03076 109 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 86355730 Common galE1 UDP-glucose 4-epimerase protein RHE_CH00069 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 86357629 Common - putative integrase protein RHE_CH02009 7 None None None 86355743 Common - probable sugar ABC transporter, substrate-binding protein RHE_CH00082 59 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86359161 Common - putative Na+/bile acid cotransporter protein RHE_CH03570 55 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 86358071 Common - probable sugar ABC transporter, permease protein RHE_CH02459 158 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 86358061 Common - probable transcriptional regulator protein, LysR family RHE_CH02449 179 COG0583 LysR, Transcriptional regulator Transcription 86358221 Common coxP cytochrome-c oxidase subunit III protein RHE_CH02614 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 86358059 Common - putative multidrug resistance transporter protein RHE_CH02447 206 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86357415 Common nasT two-component response regulator protein RHE_CH01785 104 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 86356434 Common ppx1 exopolyphosphatase protein RHE_CH00788 179 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 86357180 Common celA cellulose synthase protein RHE_CH01542 138 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 86355956 Common - putative phenylacetic acid degradation protein RHE_CH00299 61 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 86358884 Common - probable alcohol dehydrogenase protein RHE_CH03285 203 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 86357787 Nonpathogen - hypothetical protein RHE_CH02170 1 None None None 86359238 Common xylA xylose isomerase RHE_CH03648 70 COG2115 XylA, Xylose isomerase Carbohydrate transport and metabolism 86358617 Common proC pyrroline-5-carboxylate reductase RHE_CH03015 214 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 86356953 Common - putative permease protein RHE_CH01313 118 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86359166 Common - probable two-component response regulator protein RHE_CH03575 219 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 86355701 Common - probable protein-N(pi)-phosphohistidine-sugar phosphotransferase protein (component of thephosphoenolpyruvate-dependent sugar phosphotransferasesystem) RHE_CH00033 95 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 86358042 Nonpathogen - hypothetical protein RHE_CH02429 6 None None None 86355814 Common gmk1 guanylate kinase (GMP kinase) protein RHE_CH00154 94 COG3709 COG3709, Uncharacterized component of phosphonate metabolism Inorganic ion transport and metabolism 86358440 Common recN DNA repair protein RHE_CH02837 198 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 86357470 Nonpathogen - hypothetical protein RHE_CH01843 1 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 86359669 Common leuD isopropylmalate isomerase small subunit RHE_CH04091 212 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 86356884 Common - probable molecular chaperone small heat shock protein, hsp20 family RHE_CH01244 72 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 86357291 Common secE preprotein translocase subunit SecE RHE_CH01661 17 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 86358746 Common - hypothetical protein RHE_CH03145 71 COG4121 COG4121, Uncharacterized conserved protein Function unknown 86358906 Common - probable urease-associated protein RHE_CH03307 26 COG3755 COG3755, Uncharacterized protein conserved in bacteria Function unknown 86359024 Common - hypothetical protein RHE_CH03432 64 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 86356315 Common - hypothetical protein RHE_CH00664 14 COG3334 COG3334, Uncharacterized conserved protein Function unknown 86359541 Common trmD tRNA (guanine-N(1)-)-methyltransferase RHE_CH03961 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 86359617 Common - hypothetical protein RHE_CH04038 18 COG4821 COG4821, Uncharacterized protein containing SIS (Sugar ISomerase) phosphosugar binding domain General function prediction only 86356029 Common lnt apolipoprotein N-acyltransferase RHE_CH00372 161 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 86357659 Common - putative translation initiation inhibitor protein RHE_CH02040 53 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 86356654 Common - hypothetical protein RHE_CH01008 22 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 86356039 Common - putative universal stress protein RHE_CH00382 26 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 86358716 Common - probable oxidoreductase protein RHE_CH03115 127 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 86356355 Common zwf1 glucose-6-phosphate 1-dehydrogenase RHE_CH00704 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 86355673 Common coaE dephospho-CoA kinase protein RHE_CH00004 205 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 86357016 Common - probable protein secretion protein, HlyD family RHE_CH01378 128 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 86358032 Common - probable amino acid ABC transporter, permease protein RHE_CH02419 172 COG4215 ArtQ, ABC-type arginine transport system, permease component Amino acid transport and metabolism 162329634 Common rplY 50S ribosomal protein L25/general stress protein Ctc RHE_CH03025 193 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 86356670 Common - hypothetical protein RHE_CH01025 3 None None None 86358446 Common ddl D-alanine--D-alanine ligase RHE_CH02843 210 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 86356042 Common - hypothetical protein RHE_CH00385 6 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 86358291 Nonpathogen - hypothetical protein RHE_CH02685 1 None None None 86358052 Common - putative succinoglycan biosynthesis protein RHE_CH02440 41 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 86356626 Common - hypothetical protein RHE_CH00980 11 None None None 86356365 Common potF spermidine/putrescine ABC transporter, substrate-binding protein RHE_CH00714 130 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 86358514 Nonpathogen - hypothetical protein RHE_CH02911 1 None None None 86358216 Common - probable peptide ABC transporter, ATP-binding protein RHE_CH02609 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 86357241 Common - hypothetical protein RHE_CH01607 3 None None None 86356512 Common atpF1 F0F1 ATP synthase subunit B' RHE_CH00866 49 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 86356962 Common - putative RNA polymerase sigma factor protein (sigma-70) RHE_CH01322 42 COG4941 COG4941, Predicted RNA polymerase sigma factor containing a TPR repeat domain Transcription 86358929 Nonpathogen - hypothetical protein RHE_CH03331 1 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 86357209 Common - probable transcriptional regulator protein, LysR family RHE_CH01572 193 COG0583 LysR, Transcriptional regulator Transcription 86356032 Common phoH phosphate starvation inducible protein RHE_CH00375 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 86356969 Common - hypothetical protein RHE_CH01329 16 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 86359369 Common gltX2 glutamyl-Q tRNA(Asp) synthetase RHE_CH03786 246 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 86359086 Common tkt transketolase RHE_CH03495 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 86356904 Common - short chain dehydrogenase RHE_CH01264 90 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 86359379 Common argH argininosuccinate lyase RHE_CH03796 230 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 86359568 Common - probable sugar ABC transporter, ATP-binding protein RHE_CH03989 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 86357395 Common - probable transcriptional regulator protein, LysR family RHE_CH01765 183 COG0583 LysR, Transcriptional regulator Transcription 86357652 Nonpathogen - hypothetical protein RHE_CH02033 1 None None None 86355948 Common - probable transcriptional regulator protein, LysR family RHE_CH00291 179 COG0583 LysR, Transcriptional regulator Transcription 86355746 Common - probable oxidoreductase protein RHE_CH00085 165 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 86356861 Common - putative regulator protein RHE_CH01221 40 COG5616 COG5616, Predicted integral membrane protein Function unknown 86358707 Common - putative lipase protein RHE_CH03106 136 COG0657 Aes, Esterase/lipase Lipid metabolism 86357120 Common gstch7 glutathione S-transferase protein RHE_CH01482 61 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 86357971 Common - hypothetical protein RHE_CH02356 15 COG1737 RpiR, Transcriptional regulators Transcription 86357160 Common - putative acetyltransferase protein RHE_CH01522 94 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 86356319 Common - putative glycosyltransferase TPR domain protein RHE_CH00668 53 COG3914 Spy, Predicted O-linked N-acetylglucosamine transferase, SPINDLY family Posttranslational modification, protein turnover, chaperones 86355968 Nonpathogen - hypothetical protein RHE_CH00311 2 None None None 86358470 Common - probable SAM-dependent methyltransferase protein RHE_CH02867 82 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 86358523 Nonpathogen - hypothetical protein RHE_CH02921 1 None None None 86356057 Common sppA proteinase IV protein RHE_CH00400 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 86356098 Common regM two-component sensor histidine kinase protein RHE_CH00441 212 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 86356806 Common - hypothetical protein RHE_CH01166 7 None None None 86359453 Common atpA F0F1 ATP synthase subunit alpha RHE_CH03872 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 86359103 Common - hypothetical protein RHE_CH03512 149 COG1360 MotB, Flagellar motor protein Cell motility and secretion 86358236 Common - hypothetical protein RHE_CH02629 2 None None None 86359095 Nonpathogen - hypothetical protein RHE_CH03504 7 COG5509 COG5509, Uncharacterized small protein containing a coiled-coil domain Function unknown 86357087 Common ksgA dimethyladenosine transferase RHE_CH01449 247 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 86357515 Nonpathogen - hypothetical protein RHE_CH01894 1 None None None 86358023 Common - probable maleylpyruvate isomerase protein RHE_CH02410 70 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 86355982 Common cysK1 cysteine synthase protein RHE_CH00325 219 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 86358598 Common lpcA galactosyltransferase protein RHE_CH02996 20 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 86357226 Common lon ATP-dependent protease LA protein RHE_CH01589 229 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 86358995 Common - hypothetical protein RHE_CH03397 19 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 86359275 Common - putative transcriptional regulator protein, ROK family RHE_CH03685 102 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 86358491 Common - putative N-formylglutamate amidohydrolase protein RHE_CH02888 41 COG3931 COG3931, Predicted N-formylglutamate amidohydrolase Amino acid transport and metabolism 86359190 Common soxGch sarcosine oxidase gamma subunit protein RHE_CH03600 27 COG4583 COG4583, Sarcosine oxidase gamma subunit Amino acid transport and metabolism 86358366 Common - probable transcriptional regulator protein, AsnC family RHE_CH02762 117 COG1522 Lrp, Transcriptional regulators Transcription 86359593 Common - glutathione S-transferase protein RHE_CH04014 67 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 86358110 Common - probable transcriptional regulator protein, LysR family RHE_CH02498 192 COG0583 LysR, Transcriptional regulator Transcription 86359029 Common - hypothetical protein RHE_CH03437 14 None None None 86358401 Common hflK hydrolase serine protease transmembrane subunit K protein RHE_CH02797 155 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 86358700 Common oppD oligopeptide ABC transporter, ATP-binding protein RHE_CH03099 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 86359374 Common - hypothetical protein RHE_CH03791 57 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 86359515 Common - probable tyrosine phosphatase protein RHE_CH03935 140 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 86358894 Common - probable nitrate/sulfonate ABC transporter, permease protein RHE_CH03295 84 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 86357922 Common - probable acetyltransferase protein RHE_CH02307 47 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 86356262 Common - probable transcriptional regulator protein, LacI family RHE_CH00611 130 COG1609 PurR, Transcriptional regulators Transcription 86355825 Common phnI C-P (carbon-phosphorus) lyase component protein RHE_CH00165 45 COG3626 PhnI, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 86356363 Common aceA isocitrate lyase protein RHE_CH00712 128 COG2224 AceA, Isocitrate lyase Energy production and conversion 86356120 Common frcR sugar transcriptional regulator protein, ROK family RHE_CH00464 86 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 86356314 Common flgI flagellar basal body P-ring protein RHE_CH00663 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 86358529 Common - probable Clp protease protein RHE_CH02927 43 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 86356028 Common - probable transcriptional regulator protein RHE_CH00371 40 COG1396 HipB, Predicted transcriptional regulators Transcription 86357982 Common - hypothetical protein RHE_CH02367 9 None None None 86355934 Common xseA exodeoxyribonuclease VII large subunit RHE_CH00276 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 86359646 Common proB gamma-glutamyl kinase RHE_CH04068 189 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 86357625 Common - putative sensory box/GGDEF family protein RHE_CH02005 196 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 86356860 Common bla beta-lactamase protein RHE_CH01220 65 COG2367 PenP, Beta-lactamase class A Defense mechanisms 86358494 Common - probable ABC transporter, permease protein RHE_CH02891 90 COG4132 COG4132, ABC-type uncharacterized transport system, permease component General function prediction only 86358991 Common - probable acetyltransferase protein RHE_CH03393 35 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 86357427 Common - hypothetical conserved membrane protein RHE_CH01797 25 COG5478 COG5478, Predicted small integral membrane protein Function unknown 86356496 Common - putative sensory box/GGDEF family protein RHE_CH00850 177 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 86358597 Nonpathogen kdsB2 3-deoxy-manno-octulosonate cytidylyltransferase protein RHE_CH02995 2 None None None 86355980 Common - probable Mg-chelatase protein RHE_CH00323 194 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 86356253 Common - probable translation initiation inhibitor protein RHE_CH00602 109 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 86357130 Common ppx2 exopolyphosphatase protein RHE_CH01492 173 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 86359119 Common - putative transporter, permease protein RHE_CH03528 36 COG0730 COG0730, Predicted permeases General function prediction only 86356438 Common - probable efflux transporter, permease protein RHE_CH00792 203 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86359324 Common nuoM3 NADH-ubiquinone oxidoreductase chain M protein RHE_CH03734 209 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 86357513 Common - putative RTX toxin hemolysin-type calcium-binding protein RHE_CH01892 75 COG3889 COG3889, Predicted solute binding protein General function prediction only 86357471 Common - hypothetical protein RHE_CH01844 80 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 86356421 Common - putative methyltransferase protein RHE_CH00772 59 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 86357390 Common - hypothetical protein RHE_CH01760 14 COG5453 COG5453, Uncharacterized conserved protein Function unknown 86357191 Common - probable acetyltransferase protein RHE_CH01554 11 COG0456 RimI, Acetyltransferases General function prediction only 86357914 Common - putative 2-oxo-hepta-3-ene-1,7-dioate hydratase protein RHE_CH02299 63 COG3971 COG3971, 2-keto-4-pentenoate hydratase Secondary metabolites biosynthesis, transport, and catabolism 86356761 Common - probable short-chain dehydrogenase protein RHE_CH01119 6 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 86359183 Common glgP glycogen phosphorylase protein RHE_CH03593 144 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 86355769 Common fabI1 enoyl-(acyl carrier protein) reductase RHE_CH00109 211 COG0623 FabI, Enoyl- acyl-carrier-protein 86357082 Common acpP acyl carrier protein RHE_CH01444 209 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 86359102 Common - putative RNA polymerase sigma factor protein, ECF-family RHE_CH03511 41 COG4941 COG4941, Predicted RNA polymerase sigma factor containing a TPR repeat domain Transcription 86358551 Common - hypothetical protein RHE_CH02949 16 COG4274 COG4274, Uncharacterized conserved protein Function unknown 86356300 Common - hypothetical protein RHE_CH00649 9 None None None 86356059 Common - hypothetical protein RHE_CH00402 29 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 86359441 Common - probable transcriptional regulator protein, LysR family RHE_CH03860 181 COG0583 LysR, Transcriptional regulator Transcription 86359608 Common - probable transcriptional regulator protein, MarR family RHE_CH04029 24 COG1846 MarR, Transcriptional regulators Transcription 86357784 Common phnA alkilphosphonate uptake protein RHE_CH02167 106 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 86359513 Common - hypothetical protein RHE_CH03933 37 COG3339 COG3339, Uncharacterized conserved protein Function unknown 86355812 Common ftsK1 cell division protein RHE_CH00152 197 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 86356101 Nonpathogen - hypothetical protein RHE_CH00445 2 None None None 86358701 Common oppF oligopeptide ABC transporter, ATP-binding protein RHE_CH03100 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 86356612 Common - hypothetical protein RHE_CH00966 130 COG1678 COG1678, Putative transcriptional regulator Transcription 86358369 Common - probable transcriptional regulator protein, TetR family RHE_CH02765 81 COG1309 AcrR, Transcriptional regulator Transcription 86356063 Common - probable sigma 54 modulation protein RHE_CH00406 47 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 86356433 Common - probable insertion sequence transposase protein RHE_CH00785 18 None None None 86358351 Nonpathogen - hypothetical protein RHE_CH02746 1 None None None 86356058 Common - hypothetical protein RHE_CH00401 20 COG5375 COG5375, Uncharacterized protein conserved in bacteria Function unknown 86356768 Common mrcB penicillin binding protein B RHE_CH01126 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 86358927 Nonpathogen - hypothetical protein RHE_CH03329 1 None None None 86357723 Common - hypothetical protein RHE_CH02104 211 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 86357977 Common - probable transcriptional regulator protein, LacI family RHE_CH02362 126 COG1609 PurR, Transcriptional regulators Transcription 86358892 Common - hypothetical protein RHE_CH03293 23 COG4101 COG4101, Predicted mannose-6-phosphate isomerase Carbohydrate transport and metabolism 86359109 Common - putative methyl-accepting chemotaxis protein RHE_CH03518 148 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 86356003 Common - putative biphenyl-2,3-diol 1,2-dioxygenase protein RHE_CH00346 45 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 86358073 Common - probable sugar ABC transporter, substrate-binding protein RHE_CH02461 67 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86357167 Common - hypothetical protein RHE_CH01529 22 COG5452 COG5452, Uncharacterized conserved protein Function unknown 86355965 Common - putative iron-sulfur cluster binding protein RHE_CH00308 133 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 86357987 Common - hypothetical conserved membrane protein RHE_CH02372 46 COG4420 COG4420, Predicted membrane protein Function unknown 86358728 Common - probable transcriptional regulator protein, LysR family RHE_CH03127 131 COG0583 LysR, Transcriptional regulator Transcription 86359489 Common - hypothetical protein RHE_CH03908 36 COG4103 COG4103, Uncharacterized protein conserved in bacteria Function unknown 86359537 Common ffh signal recognition particle GTP-binding protein RHE_CH03957 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 86356036 Common rimI ribosomal-protein-alanine N-acetyltransferase protein RHE_CH00379 82 COG0456 RimI, Acetyltransferases General function prediction only 86356852 Common - probable sugar ABC transporter, ATP-binding protein RHE_CH01212 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 86357745 Common afuA1 iron(III) ABC transporter, substrate-binding protein RHE_CH02126 104 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 86355706 Common - hypothetical protein RHE_CH00038 108 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 86357541 Common omp1 outer membrane lipoprotein RHE_CH01920 158 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 86358083 Common - putative glyoxalase protein RHE_CH02471 31 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 86358767 Common gbpR transcriptional regulator protein, LysR family (possibly activator of the expression of chvE protein) RHE_CH03166 164 COG0583 LysR, Transcriptional regulator Transcription 86356307 Common fliI flagellum-specific ATP synthase RHE_CH00656 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 86356865 Common - hypothetical protein RHE_CH01225 44 COG3797 COG3797, Uncharacterized protein conserved in bacteria Function unknown 86359136 Common - hypothetical protein RHE_CH03545 38 COG3492 COG3492, Uncharacterized protein conserved in bacteria Function unknown 86357139 Common - putative permease protein RHE_CH01501 21 None None None 86357826 Common - hypothetical protein RHE_CH02210 9 None None None 86357038 Common sodC superoxide dismutase protein RHE_CH01400 85 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 86358223 Common coxN cytochrome-c oxidase subunit I protein RHE_CH02616 169 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 86356607 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase RHE_CH00961 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 86357775 Common metS methionyl-tRNA synthetase RHE_CH02157 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 86358747 Common - probable two-component sensor histidine kinase/response regulator hybrid protein RHE_CH03146 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 86356857 Common - probable acetyltransferase protein RHE_CH01217 34 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 86357224 Common clpP ATP-dependent Clp protease proteolytic subunit RHE_CH01587 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 86359439 Common fdsB formate dehydrogenase, beta subunit protein RHE_CH03858 168 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 86356043 Common mviN virulence factor transmembrane protein RHE_CH00386 189 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 86357667 Common - probable creatininase (creatinine amidohydrolase) protein RHE_CH02048 87 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 86359396 Common - hypothetical protein RHE_CH03813 57 COG3542 COG3542, Uncharacterized conserved protein Function unknown 86356813 Common - probable transcriptional regulator protein, MarR family RHE_CH01173 125 COG1846 MarR, Transcriptional regulators Transcription 86356801 Common mcpY methyl-accepting chemotaxis protein RHE_CH01161 158 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 86357252 Common nuoN1 NADH dehydrogenase subunit N RHE_CH01618 208 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 86355971 Common pyrF orotidine 5'-phosphate decarboxylase RHE_CH00314 164 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 86356623 Common rimJ alanine acetyltransferase (ribosomal) protein RHE_CH00977 123 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 86356948 Common etf electrotransfer ubiquinone oxidoreductase protein RHE_CH01308 110 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 86358704 Common gstI glutamine synthetase translation inhibitor protein RHE_CH03103 3 None None None 86355793 Common cycM cytochrome-c protein RHE_CH00133 56 COG3474 COG3474, Cytochrome c2 Energy production and conversion 86356900 Common - hypothetical protein RHE_CH01260 18 COG5402 COG5402, Uncharacterized conserved protein Function unknown 86359352 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein RHE_CH03768 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 86357502 Common - hypothetical protein RHE_CH01876 3 None None None 86357302 Common fusA2 elongation factor G RHE_CH01672 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 86359389 Common chaC cation transporter protein RHE_CH03806 44 COG3703 ChaC, Uncharacterized protein involved in cation transport Inorganic ion transport and metabolism 86356030 Common - putative hemolysin protein RHE_CH00373 214 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 86356135 Common - hypothetical protein RHE_CH00479 36 None None None 86356354 Common pgl 6-phosphogluconolactonase protein RHE_CH00703 113 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 86358809 Common - putative methyltransferase protein RHE_CH03209 30 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 86356573 Common - putative acetyltransferase protein RHE_CH00927 35 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 86355681 Common gyrB DNA gyrase subunit B RHE_CH00012 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 86357660 Common - probable NAD(P)H dehydrogenase protein RHE_CH02041 71 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 86358297 Common - probable transcriptional regulator protein, LysR family RHE_CH02691 179 COG0583 LysR, Transcriptional regulator Transcription 86356958 Common - hypothetical conserved membrane protein RHE_CH01318 9 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 86358740 Common allA ureidoglycolate hydrolase RHE_CH03139 34 COG3194 DAL3, Ureidoglycolate hydrolase Nucleotide transport and metabolism 86358066 Common - probable oxidoreductase protein RHE_CH02454 189 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 86356905 Common - hypothetical protein RHE_CH01265 3 None None None 86358754 Common - probable transcriptional regulator protein, AraC family RHE_CH03153 118 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 86357118 Common - short chain dehydrogenase RHE_CH01480 217 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 86359021 Common - probable hippurate hydrolase protein RHE_CH03429 171 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 86359272 Common smoEch sorbitol/mannitol ABC transporter, substrate-binding protein RHE_CH03682 110 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86356200 Common - putative transcriptional regulator protein RHE_CH00547 120 COG1959 COG1959, Predicted transcriptional regulator Transcription 86358030 Common - putative outer membrane protein, OmpA family RHE_CH02417 81 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 86356955 Common - probable glutamine synthetase protein RHE_CH01315 226 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 86359614 Common - probable transcriptional regulator protein, GntR family RHE_CH04035 137 COG2188 PhnF, Transcriptional regulators Transcription 86358981 Common - probable glycosyltransferase protein RHE_CH03383 116 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 86358414 Common flaCch5 flagellin C protein RHE_CH02811 40 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 86355822 Common - probable phosphonate ABC transporter, ATP-binding protein RHE_CH00162 249 COG4778 PhnL, ABC-type phosphonate transport system, ATPase component Inorganic ion transport and metabolism 86359265 Common - putative transcriptional regulator protein RHE_CH03675 31 COG1737 RpiR, Transcriptional regulators Transcription 86356562 Common - exodeoxyribonuclease VII small subunit RHE_CH00916 123 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 86358950 Common - short chain dehydrogenase RHE_CH03352 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 86355698 Common - probable two-component sensor histidine kinase protein RHE_CH00030 221 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 86358106 Common cobQ cobyric acid synthase RHE_CH02494 158 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 86359654 Common - hypothetical protein RHE_CH04076 167 COG1576 COG1576, Uncharacterized conserved protein Function unknown 86359017 Common - putative oxidoreductase protein RHE_CH03425 111 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 86356198 Common - hypothetical protein RHE_CH00545 59 COG1284 COG1284, Uncharacterized conserved protein Function unknown 86356407 Common asnB asparagine synthetase (glutamine-hydrolyzing) protein RHE_CH00758 168 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 86357600 Nonpathogen - putative hydrolase protein RHE_CH01980 8 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 86356790 Common - putative transporter, permease protein RHE_CH01148 39 COG3694 COG3694, ABC-type uncharacterized transport system, permease component General function prediction only 86356894 Common - putative methyl-accepting chemotaxis protein RHE_CH01254 144 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 86358462 Common - probable transglycosylase protein RHE_CH02859 143 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 86357335 Common - hypothetical protein RHE_CH01705 15 COG4461 LprI, Uncharacterized protein conserved in bacteria, putative lipoprotein Function unknown 162329644 Common ate arginyl-tRNA-protein transferase RHE_CH01502 85 COG2935 COG2935, Putative arginyl-tRNA:protein arginylyltransferase Posttranslational modification, protein turnover, chaperones 86356740 Common - hypothetical protein RHE_CH01097 7 None None None 86359215 Common - putative cobalamin synthesis protein, P47K family RHE_CH03625 128 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 86357381 Nonpathogen - hypothetical protein RHE_CH01751 1 None None None 86359490 Common guaA2 glutamine amidotransferase RHE_CH03909 109 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 86356992 Common - probable glycosyltransferase protein RHE_CH01354 158 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 86359417 Nonpathogen - hypothetical protein RHE_CH03835 3 None None None 86356187 Common - hypothetical protein RHE_CH00534 15 None None None 86356446 Common - probable transcriptional regulator protein, LysR family RHE_CH00800 190 COG0583 LysR, Transcriptional regulator Transcription 86355939 Common gstch1 glutathione S-transferase protein RHE_CH00281 105 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 86355906 Common lepA GTP-binding protein LepA RHE_CH00248 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 86356346 Common aglR transcriptional regulator protein, LacI family RHE_CH00695 127 COG1609 PurR, Transcriptional regulators Transcription 86358013 Common tktB transketolase N-terminal subunit protein RHE_CH02398 223 COG3959 COG3959, Transketolase, N-terminal subunit Carbohydrate transport and metabolism 86358503 Common - probable transcriptional regulator protein RHE_CH02900 132 COG2188 PhnF, Transcriptional regulators Transcription 86357819 Common - putative phosphoesterase protein RHE_CH02203 121 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 86357287 Nonpathogen - putative metalloprotease inhibitor (transcriptional regulator) protein RHE_CH01654 6 None None None 86357961 Common - putative ABC transporter protein RHE_CH02346 27 COG3218 COG3218, ABC-type uncharacterized transport system, auxiliary component General function prediction only 86356371 Common - putative two-component sensor histidine kinase protein RHE_CH00720 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 86359141 Common pabB para-aminobenzoate synthase component I RHE_CH03550 220 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 86358300 Nonpathogen - hypothetical protein RHE_CH02694 2 None None None 86358531 Nonpathogen - hypothetical protein RHE_CH02929 1 None None None 86356915 Common - probable transcriptional regulator protein, GntR family RHE_CH01275 149 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 86356290 Common cheA chemotaxis two-component sensor histidine kinase protein RHE_CH00639 164 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 86358343 Nonpathogen - hypothetical protein RHE_CH02738 5 None None None 86356399 Common - probable acetyltransferase protein RHE_CH00750 120 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 86355721 Common - hypothetical protein RHE_CH00053 69 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 86356125 Common pyrC dihydroorotase RHE_CH00469 90 COG0418 PyrC, Dihydroorotase Nucleotide transport and metabolism 86359013 Nonpathogen - hypothetical protein RHE_CH03421 3 COG5650 COG5650, Predicted integral membrane protein Function unknown 86358988 Nonpathogen - hypothetical protein RHE_CH03390 1 None None None 86359673 Common - putative transporter, permease protein RHE_CH04095 120 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86359030 Common - hypothetical protein RHE_CH03438 13 None None None 86356597 Common - hypothetical protein RHE_CH00951 13 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 86358329 Common afuB2 iron(III) ABC transporter, permease protein RHE_CH02724 216 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 86359581 Common pyc pyruvate carboxylase RHE_CH04002 240 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 86356842 Common - hypothetical protein RHE_CH01202 5 None None None 86358157 Common - probable acyl-CoA hydrolase protein RHE_CH02548 132 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 86355923 Common - hypothetical protein RHE_CH00265 7 None None None 86359001 Common purC2 phosphoribosylaminoimidazole-succinocarboxamide synthase RHE_CH03409 195 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 86359259 Common - probable 6-O-methylguanine-DNA methyltransferase protein RHE_CH03669 210 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 86358544 Nonpathogen - hypothetical protein RHE_CH02942 1 None None None 86355784 Common - hypothetical protein RHE_CH00124 78 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 86359348 Common - probable SAM-dependent methyltransferase protein RHE_CH03764 72 None None None 86356802 Common - putative peroxidase protein RHE_CH01162 168 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 86358381 Common - putative transcriptional regulator protein RHE_CH02777 54 COG1959 COG1959, Predicted transcriptional regulator Transcription 86357639 Common - hypothetical protein RHE_CH02020 7 None None None 86357525 Common - hypothetical protein RHE_CH01904 18 None None None 86356268 Common - putative DNA ligase protein RHE_CH00617 101 COG3285 COG3285, Predicted eukaryotic-type DNA primase DNA replication, recombination, and repair 86357995 Common rpiA ribose-5-phosphate isomerase A RHE_CH02380 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 86357367 Nonpathogen - hypothetical protein RHE_CH01737 2 COG3941 COG3941, Mu-like prophage protein General function prediction only 86359094 Common - probable transporter permease protein RHE_CH03503 69 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86356385 Common dppAch1 dipeptide ABC transporter, substrate-binding protein RHE_CH00736 208 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 86358671 Common clpP3 ATP-dependent Clp protease proteolytic subunit RHE_CH03069 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 86355714 Common - hypothetical protein RHE_CH00046 11 None None None 86357876 Common - hypothetical protein RHE_CH02261 32 None None None 86358790 Common - probable sugar ABC transporter, ATP-binding protein RHE_CH03190 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 86357919 Common grlA glutaredoxin protein RHE_CH02304 127 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 86355815 Common phnM1 phosphonate metabolism protein RHE_CH00155 52 COG3454 COG3454, Metal-dependent hydrolase involved in phosphonate metabolism Inorganic ion transport and metabolism 86358322 Common chrA chromate transporter protein RHE_CH02716 100 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 86357915 Common hpaI 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase protein (4-hydroxyphenylacetate catabolism protein) RHE_CH02300 74 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 86358802 Nonpathogen - hypothetical protein RHE_CH03202 1 None None None 86356104 Common pmtA phospholipid N-methyltransferase protein RHE_CH00448 35 COG3963 COG3963, Phospholipid N-methyltransferase Lipid metabolism 86356883 Common - hypothetical protein RHE_CH01243 6 None None None 86358371 Common - putative transcriptional regulator protein RHE_CH02767 141 COG1733 COG1733, Predicted transcriptional regulators Transcription 86359382 Common - probable two-component response regulator protein RHE_CH03799 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 86357858 Common gcvP glycine dehydrogenase RHE_CH02243 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 86359699 Common gidB glucose-inhibited division protein B RHE_CH04121 131 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 86357632 Common - putative insertion sequence transposase protein RHE_CH02012 59 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 86357703 Common - putative ABC transporter, substrate-binding protein RHE_CH02084 82 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 86358799 Common - putative surface saccharide ABC transporter, ATP-binding and permease protein RHE_CH03199 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 86359557 Common - hypothetical protein RHE_CH03977 101 COG2835 COG2835, Uncharacterized conserved protein Function unknown 86358606 Common - putative transporter, permease protein RHE_CH03004 120 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 86357609 Nonpathogen - hypothetical protein RHE_CH01989 1 None None None 86359286 Common - probable transcriptional regulator protein, GntR family RHE_CH03696 105 COG2186 FadR, Transcriptional regulators Transcription 86356506 Common corAch magnesium/cobalt transporter protein RHE_CH00860 155 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 86356070 Common stdB plasmid stability protein RHE_CH00413 55 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 86357100 Common - probable amino acid ABC transporter, ATP-binding protein RHE_CH01462 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 86358425 Common - putative pyrimidine reductase protein RHE_CH02822 48 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 86357271 Common rnr exoribonuclease protein RHE_CH01637 192 COG0557 VacB, Exoribonuclease R Transcription 86355674 Common dnaQ DNA polymerase III subunit epsilon RHE_CH00005 189 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 86358576 Common lrp leucine-responsive transcriptional regulator protein, AsnC family RHE_CH02974 152 COG1522 Lrp, Transcriptional regulators Transcription 86359432 Common - putative transcriptional regulator protein RHE_CH03850 125 COG1522 Lrp, Transcriptional regulators Transcription 86358916 Common - probable urea or short-chain amide ABC transporter, substrate-binding protein RHE_CH03317 86 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 86355754 Common gabT 4-aminobutyrate aminotransferase RHE_CH00093 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 86356924 Common - putative transporter, permease protein RHE_CH01284 36 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86357790 Common ppiD1 peptidyl prolyl cis-trans isomerase D signal peptide protein RHE_CH02173 112 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 86359578 Common - probable lactoylglutathione lyase protein RHE_CH03999 17 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 86356967 Common amn AMP nucleosidase RHE_CH01327 54 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 86359670 Common - putative L-serine dehydratase protein RHE_CH04092 177 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 86357266 Common celR1 two-component response regulator protein RHE_CH01632 224 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 86358480 Common - probable acyl-CoA transferases/L-carnitine dehydratase protein RHE_CH02877 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 86357280 Common amiC n-acetylmuramoyl-l-alanine amidase protein RHE_CH01646 175 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 86357799 Common cisZ citrate synthase protein RHE_CH02182 116 COG0372 GltA, Citrate synthase Energy production and conversion 86357246 Common nuoH1 NADH dehydrogenase subunit H RHE_CH01612 186 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 86357528 Common clpA ATP-dependent Clp protease, ATP-binding subunit protein RHE_CH01907 233 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 86356462 Common - hypothetical protein RHE_CH00816 2 None None None 86358620 Common lgt prolipoprotein diacylglyceryl transferase RHE_CH03018 205 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 86357548 Common - hypothetical protein RHE_CH01927 153 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 86357691 Common - hypothetical protein RHE_CH02072 4 None None None 86358136 Common - probable two-component response regulator protein RHE_CH02526 183 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 86358725 Common xdhA xanthine dehydrogenase protein RHE_CH03124 123 COG4630 XdhA, Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A Nucleotide transport and metabolism 86356465 Common - hypothetical protein RHE_CH00819 12 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 86358846 Common lpsL UDP-glucuronic acid epimerase protein RHE_CH03247 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 86356216 Common - hypothetical protein RHE_CH00563 10 COG4319 COG4319, Ketosteroid isomerase homolog Function unknown 86358629 Common - putative amino acid ABC transporter, substrate-binding protein RHE_CH03027 24 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 86359306 Common nrdE ribonucleotide-diphosphate reductase subunit alpha RHE_CH03716 217 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 86357857 Common gcvH glycine cleavage system H protein RHE_CH02242 186 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 86359250 Common - putative spermidine/putrescine ABC transporter, substrate-binding protein RHE_CH03660 102 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 86359571 Common dppAch3 dipeptide ABC transporter, substrate-binding protein RHE_CH03992 193 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 86355750 Common uxuB D-mannonate oxidoreductase protein RHE_CH00089 90 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 86356078 Common - putative hydrolase protein RHE_CH00421 45 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 86359526 Nonpathogen - hypothetical protein RHE_CH03946 1 None None None 86356849 Common - probable myo-inositol 2-dehydrogenase protein RHE_CH01209 148 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 86359128 Common - probable threonine dehydratase protein RHE_CH03537 207 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 86357094 Common pepA leucyl aminopeptidase RHE_CH01456 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 86356152 Common - probable transcriptional regulator protein RHE_CH00496 67 COG1802 GntR, Transcriptional regulators Transcription 86357830 Common sda L-serine dehydratase protein RHE_CH02214 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 86358238 Nonpathogen - hypothetical protein RHE_CH02631 1 None None None 86358428 Common - putative branched-chain amino acid permease (azaleucine resistance) protein RHE_CH02825 102 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 86358202 Common - probable acetyltransferase protein RHE_CH02595 64 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 86357487 Common - putative inner membrane protein RHE_CH01861 62 COG3326 COG3326, Predicted membrane protein Function unknown 86357907 Common - probable amino acid ABC transporter, ATP-binding protein RHE_CH02292 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 86358785 Common - hypothetical protein RHE_CH03185 8 COG3779 COG3779, Uncharacterized protein conserved in bacteria Function unknown 86357068 Common radA DNA repair protein RadA RHE_CH01430 203 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 86359052 Common omp2 outer membrane lipoprotein RHE_CH03461 154 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 86359189 Common nodN dehydratase nodulation protein RHE_CH03599 65 COG2030 MaoC, Acyl dehydratase Lipid metabolism 86358836 Common - hypothetical protein RHE_CH03237 16 COG3672 COG3672, Predicted periplasmic protein Function unknown 86357920 Common - probable drug resistance transporter protein, Bcr/CflA family RHE_CH02305 218 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86358198 Common - hypothetical protein RHE_CH02591 64 COG3865 COG3865, Uncharacterized protein conserved in bacteria Function unknown 86359198 Common - probable O-linked GlcNAc transferase protein RHE_CH03608 133 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 86359227 Common - hypothetical protein RHE_CH03637 8 COG5607 COG5607, Uncharacterized conserved protein Function unknown 86359288 Nonpathogen - hypothetical conserved membrane protein RHE_CH03698 2 COG2259 COG2259, Predicted membrane protein Function unknown 86357874 Nonpathogen - hypothetical protein RHE_CH02259 1 None None None 86358922 Common braF amino acid ABC transporter, ATP-binding protein RHE_CH03324 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 86357537 Common frr ribosome recycling factor RHE_CH01916 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 86356380 Common iolA methylmalonate-semialdehyde dehydrogenase (acylating) protein RHE_CH00731 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 86359590 Common ispA geranyltranstransferase protein RHE_CH04011 240 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 86358170 Nonpathogen - hypothetical protein RHE_CH02561 1 None None None 86358430 Common - probable aminopeptidase P protein RHE_CH02827 221 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 86356881 Common - putative glycosyltransferase protein RHE_CH01241 149 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 86358613 Common - probable transcriptional regulator protein, MarR family RHE_CH03011 42 COG1846 MarR, Transcriptional regulators Transcription 86355896 Common - probable insertion sequence transposase protein, ISRm14 RHE_CH00237 24 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 86357055 Common - hypothetical protein RHE_CH01417 122 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 86357236 Common nuoA1 NADH dehydrogenase subunit A RHE_CH01602 162 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 86358856 Common - probable methyl viologen/ethidium resistance transmembrane protein RHE_CH03257 128 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 86356734 Common - hypothetical protein RHE_CH01091 3 None None None 86357142 Common hemB delta-aminolevulinic acid dehydratase RHE_CH01504 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 86358882 Common ftrA transcriptional activator FtrA RHE_CH03283 107 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 86359240 Common - probable transcriptional regulator protein, LacI family RHE_CH03650 114 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86358217 Common - hypothetical protein RHE_CH02610 154 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 86356724 Nonpathogen - hypothetical protein RHE_CH01081 1 None None None 86357403 Common sseA thiosulfate sulfurtransferase protein RHE_CH01773 145 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 86357025 Common - hypothetical protein RHE_CH01387 20 COG3216 COG3216, Uncharacterized protein conserved in bacteria Function unknown 86357076 Common - hypothetical protein RHE_CH01438 12 None None None 86356243 Common - hypothetical protein RHE_CH00592 19 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 86358047 Common - hypothetical protein RHE_CH02434 15 COG4912 COG4912, Predicted DNA alkylation repair enzyme DNA replication, recombination, and repair 86357972 Common - putative myo-inositol dehydrogenase protein RHE_CH02357 177 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 86355885 Common exoZ exopolysaccharide production (acetyltransferase) protein RHE_CH00226 84 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 86358632 Common clpS ATP-dependent Clp protease adaptor RHE_CH03030 120 COG2127 COG2127, Uncharacterized conserved protein Function unknown 86359031 Common - putative phosphoglycerate mutase protein RHE_CH03439 54 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 86358685 Common tdk thymidine kinase RHE_CH03084 92 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 86358392 Common - putative oxidoreductase protein RHE_CH02788 201 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 86357276 Common pyrB aspartate carbamoyltransferase catalytic subunit RHE_CH01642 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 86356759 Nonpathogen - hypothetical protein RHE_CH01117 1 None None None 86357685 Common - probable transcriptional regulator protein, LacI family RHE_CH02066 126 COG1609 PurR, Transcriptional regulators Transcription 86357735 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase RHE_CH02116 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 86358120 Common - hypothetical protein RHE_CH02508 27 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 86359196 Common - putative adenylate cyclase protein RHE_CH03606 85 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 86359210 Common - probable glutamine amidotransferase protein RHE_CH03620 116 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 86356196 Common - hypothetical protein RHE_CH00543 14 None None None 86356540 Common - hypothetical conserved membrane protein RHE_CH00894 28 COG3713 OmpV, Outer membrane protein V Cell envelope biogenesis, outer membrane 86359080 Common - hypothetical protein RHE_CH03489 15 COG3832 COG3832, Uncharacterized conserved protein Function unknown 86357158 Common - putative beta-D-1,6 glucosyltransferase protein RHE_CH01520 198 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 86356452 Common - probable NTP pyrophosphohydrolase protein, MuT/nudix family RHE_CH00806 29 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 86357329 Common rpoA DNA-directed RNA polymerase subunit alpha RHE_CH01699 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 86356571 Common - probable transcriptional regulator protein, LysR family RHE_CH00925 155 COG0583 LysR, Transcriptional regulator Transcription 86358583 Common - putative transcriptional regulator protein, LacI family RHE_CH02981 69 COG1609 PurR, Transcriptional regulators Transcription 86356024 Common hsp molecular chaperone small heat shock protein RHE_CH00367 64 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 86356405 Common - probable alpha-glycosyltransferase protein RHE_CH00756 38 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 86359703 Common - hypothetical protein RHE_CH04125 97 COG1981 COG1981, Predicted membrane protein Function unknown 86358166 Common nuoB2 NADH dehydrogenase subunit B RHE_CH02557 191 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 86359121 Common - hypothetical protein RHE_CH03530 12 COG5481 COG5481, Uncharacterized conserved small protein containing a coiled-coil domain Function unknown 86356719 Common - probable transcriptional regulator protein RHE_CH01076 104 COG0640 ArsR, Predicted transcriptional regulators Transcription 86356910 Common groESch3 10 kDa chaperonin, heat shock protein RHE_CH01270 214 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 86355832 Common glk glucokinase RHE_CH00172 91 COG0837 Glk, Glucokinase Carbohydrate transport and metabolism 86358374 Common - probable transcriptional regulator protein RHE_CH02770 57 COG0789 SoxR, Predicted transcriptional regulators Transcription 86356976 Common - probable transcriptional regulator protein, LysR family RHE_CH01336 79 COG0583 LysR, Transcriptional regulator Transcription 86359586 Common - probable transcriptional regulator protein, DeoR family RHE_CH04007 105 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 86356485 Common - putative glyoxalase protein RHE_CH00839 22 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 86358907 Common ureB urease subunit beta RHE_CH03308 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 86358209 Common - probable Na+/H+ antiporter protein RHE_CH02602 108 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 86356224 Common - enoyl-CoA hydratase RHE_CH00571 163 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 86358937 Common - probable RNA methylase protein RHE_CH03339 161 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 86356580 Nonpathogen ribA GTP cyclohydrolase/3,4-dihydroxy-2-butanone 4-phosphate synthase bi-functional protein (ribofalvinbiosynthesis) RHE_CH00934 1 None None None 86357803 Common - hypothetical protein RHE_CH02187 6 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 86358648 Common hemF coproporphyrinogen III oxidase RHE_CH03046 112 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 86358177 Common cspA4 cold shock protein RHE_CH02568 178 COG1278 CspC, Cold shock proteins Transcription 86356983 Common iolC myo-inositol catabolism, sugar kinase protein RHE_CH01344 160 COG3892 COG3892, Uncharacterized protein conserved in bacteria Function unknown 86356167 Common phoU phosphate uptake transcriptional regulator protein RHE_CH00513 201 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 86357182 Common celC endoglucanase (glycoside hydrolase) protein RHE_CH01544 38 COG3405 CelA, Endoglucanase Y Carbohydrate transport and metabolism 86357378 Common maiA maleylacetoacetate isomerase protein RHE_CH01748 99 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 86357552 Common eno 2-phosphoglycerate dehydratase (enolase) protein RHE_CH01931 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 86359006 Common - probable transcriptional regulator protein, LacI family RHE_CH03414 127 COG1609 PurR, Transcriptional regulators Transcription 86356189 Common - putative transcriptional regulator protein RHE_CH00536 26 COG2932 COG2932, Predicted transcriptional regulator Transcription 86358942 Common purA adenylosuccinate synthetase RHE_CH03344 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 86355841 Common pncB nicotinate phosphoribosyltransferase RHE_CH00181 61 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 86356922 Common - hypothetical protein RHE_CH01282 10 COG3179 COG3179, Predicted chitinase General function prediction only 86356766 Common - probable quinone oxidoreductase protein RHE_CH01124 184 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 86358442 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase RHE_CH02839 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 86356896 Common - hypothetical protein RHE_CH01256 10 COG5330 COG5330, Uncharacterized protein conserved in bacteria Function unknown 86356826 Common tam trans-aconitate 2-methyltransferase protein RHE_CH01186 65 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 86357596 Common - hypothetical protein RHE_CH01976 19 COG4271 COG4271, Predicted nucleotide-binding protein containing TIR -like domain Transcription 86359336 Common - putative peptidase protein, M23/M37 family RHE_CH03752 188 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 86359249 Common - probable transcriptional regulator protein, LysR family RHE_CH03659 192 COG0583 LysR, Transcriptional regulator Transcription 86356163 Common pstS phosphate ABC transporter, substrate-binding protein RHE_CH00509 124 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 86356251 Nonpathogen - hypothetical protein RHE_CH00600 2 None None None 86358146 Common - hypothetical protein RHE_CH02536 5 None None None 86355976 Common - probable methyltransferase protein RHE_CH00319 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 86356804 Common - ATP-dependent DNA ligase RHE_CH01164 102 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 86357014 Nonpathogen - hypothetical protein RHE_CH01376 3 None None None 86358472 Common - probable membrane-bound lytic murein transglycosylase protein RHE_CH02869 103 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 86358677 Common trpE anthranilate synthase includes: glutamine amidotransferase protein RHE_CH03075 238 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 86355748 Common - putative choline kinase protein RHE_CH00087 16 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 86356937 Common - probable two-component sensor histidine kinase protein RHE_CH01297 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 86358395 Common - hypothetical protein RHE_CH02791 84 COG0433 COG0433, Predicted ATPase General function prediction only 86356917 Common gstR transcriptional regulator protein, LysR family RHE_CH01277 170 COG0583 LysR, Transcriptional regulator Transcription 86359148 Common - putative membrane protease subunit protein RHE_CH03557 217 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 86358444 Common ftsA cell division protein RHE_CH02841 184 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 86357243 Common nuoF1 NADH-ubiquinone oxidoreductase chain F protein RHE_CH01609 164 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 86357354 Common - probable sugar ABC transporter, permease protein RHE_CH01724 146 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 86356159 Common - probable dioxygenase protein RHE_CH00505 94 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 86356444 Common - hypothetical protein RHE_CH00798 15 COG5331 COG5331, Uncharacterized protein conserved in bacteria Function unknown 86359087 Common gap glyceraldehyde 3-phosphate dehydrogenase protein RHE_CH03496 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 86357900 Common - hypothetical protein RHE_CH02285 10 None None None 86356929 Common cycH cytochrome-c-type biogenesis protein RHE_CH01289 42 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 86359423 Common - hypothetical protein RHE_CH03841 30 COG3533 COG3533, Uncharacterized protein conserved in bacteria Function unknown 86356710 Nonpathogen - hypothetical protein RHE_CH01067 2 None None None 86359156 Common gltD glutamate synthase subunit beta RHE_CH03565 193 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 86357840 Nonpathogen - hypothetical protein RHE_CH02225 3 None None None 86357860 Common - probable flagellar basal body rod protein RHE_CH02245 12 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 86355702 Common - hypothetical protein RHE_CH00034 10 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 86359220 Common - probable transcriptional regulator protein, LysR family RHE_CH03630 161 COG0583 LysR, Transcriptional regulator Transcription 86356685 Common - putative glycosyltransferase protein RHE_CH01041 22 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 86357756 Nonpathogen - hypothetical protein RHE_CH02137 6 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 86359394 Common - putative SAM-dependent methyltransferase protein RHE_CH03811 68 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 86357728 Common - probable multiple antibiotic resistance transporter protein RHE_CH02109 155 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 86357721 Common glnA2 glutamine synthetase protein RHE_CH02102 224 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 86358009 Common - putative iron ABC transporter, ATP-binding protein RHE_CH02394 79 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 86359688 Common htpX2 heat shock protein HtpX RHE_CH04110 191 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 86357229 Common - putative alkaline phosphatase protein RHE_CH01592 27 None None None 86358243 Common - hypothetical protein RHE_CH02636 43 COG3832 COG3832, Uncharacterized conserved protein Function unknown 86359681 Common cynT carbonic anhydrase protein RHE_CH04103 153 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 86358279 Nonpathogen - hypothetical protein RHE_CH02673 3 None None None 86357222 Common - probable cytochrome P450 hydroxylase protein RHE_CH01585 84 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 86357766 Common - putative aldehyde dehydrogenase protein RHE_CH02147 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 86357020 Common smpB SsrA-binding protein RHE_CH01382 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 86357207 Common rpsI 30S ribosomal protein S9 RHE_CH01570 243 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 86355837 Common - probable peptide ABC transporter, permease protein RHE_CH00177 220 COG4239 COG4239, ABC-type uncharacterized transport system, permease component General function prediction only 86359295 Common lacZ2 beta-D-galactosidase protein RHE_CH03705 72 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 86357320 Common rplF 50S ribosomal protein L6 RHE_CH01690 239 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 86357210 Common - enoyl-CoA hydratase RHE_CH01573 176 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 86356146 Common - probable sugar ABC transporter, permease protein RHE_CH00490 160 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 86358688 Common proV proline/glycine betaine ABC transporter, ATP-binding protein RHE_CH03087 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 86359349 Common - hypothetical protein RHE_CH03765 5 None None None 86355860 Common - hypothetical protein RHE_CH00201 14 COG4964 CpaC, Flp pilus assembly protein, secretin CpaC Intracellular trafficking and secretion 86359342 Common lysC aspartate kinase RHE_CH03758 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 86355687 Common - putative zinc metallopeptidase protein RHE_CH00019 151 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 86359138 Common - hypothetical protein RHE_CH03547 62 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 86356114 Common - hypothetical protein RHE_CH00458 89 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 86359601 Common mgpS ATP-dependent DNA helicase protein RHE_CH04022 63 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 86359366 Common - hypothetical protein RHE_CH03783 31 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 86358566 Common - probable zinc protease protein RHE_CH02964 88 COG2321 COG2321, Predicted metalloprotease General function prediction only 86356276 Common - probable two-component response regulator protein RHE_CH00625 216 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 86358410 Common - probable transcriptional regulator protein, LysR family RHE_CH02806 165 COG0583 LysR, Transcriptional regulator Transcription 86357948 Common - hypothetical protein RHE_CH02333 6 None None None 86357716 Common - hypothetical protein RHE_CH02097 13 COG2320 GrpB, Uncharacterized conserved protein Function unknown 86356092 Common - probable cold shock protein RHE_CH00435 177 COG1278 CspC, Cold shock proteins Transcription 86355787 Common - hypothetical protein RHE_CH00127 61 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 86357576 Common hflX GTP-binding protein RHE_CH01955 213 COG2262 HflX, GTPases General function prediction only 86359455 Common - hypothetical protein RHE_CH03874 6 None None None 86356836 Common - probable glutathione S-transferase protein RHE_CH01196 75 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 86356526 Common - hypothetical protein RHE_CH00880 6 None None None 86357425 Common - hypothetical protein RHE_CH01795 3 None None None 86356330 Common flgE flagellar hook protein FlgE RHE_CH00679 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 86357880 Common rhlE1 ATP dependent RNA helicase protein RHE_CH02265 236 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 86358109 Common ecnB entericidin B signal peptide protein RHE_CH02497 4 None None None 86359372 Common - hypothetical protein RHE_CH03789 14 None None None 86359480 Common - putative methyltransferase protein RHE_CH03899 59 COG3897 COG3897, Predicted methyltransferase General function prediction only 86357053 Common - putative ABC transporter, ATP-binding protein RHE_CH01415 249 COG5265 ATM1, ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components Posttranslational modification, protein turnover, chaperones 86359384 Common - hypothetical protein RHE_CH03801 2 None None None 86357461 Common - hypothetical protein RHE_CH01833 41 COG3737 COG3737, Uncharacterized conserved protein Function unknown 86355827 Common phnG C-P (carbon-phosphorus) lyase component protein RHE_CH00167 31 COG3624 PhnG, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 86356715 Common - hypothetical protein RHE_CH01072 35 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 86356334 Common flbT flagellar biosynthesis repressor FlbT RHE_CH00683 21 COG5443 FlbT, Flagellar biosynthesis regulator FlbT Cell motility and secretion 86355791 Common pheA prephenate dehydratase RHE_CH00131 213 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 86356305 Common motA flagellar motor protein MotA RHE_CH00654 96 COG1291 MotA, Flagellar motor component Cell motility and secretion 86356712 Nonpathogen - hypothetical protein RHE_CH01069 1 None None None 86356647 Common gstch4 glutathione S-transferase protein RHE_CH01001 89 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 86357464 Common gidA1 tRNA (uracil-5-)-methyltransferase Gid RHE_CH01836 175 COG1206 Gid, NAD(FAD)-utilizing enzyme possibly involved in translation Translation, ribosomal structure and biogenesis 86356533 Common - hypothetical protein RHE_CH00887 3 None None None 86356474 Common groEL chaperonin GroEL RHE_CH00828 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 86359329 Common nuoD2 NADH-ubiquinone oxidoreductase chain D protein RHE_CH03739 192 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 86356415 Common - probable glycosyltransferase protein RHE_CH00766 179 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 86356699 Nonpathogen - hypothetical protein RHE_CH01055 1 None None None 86357047 Common - hypothetical protein RHE_CH01409 107 COG2135 COG2135, Uncharacterized conserved protein Function unknown 86357189 Common - probable transcriptional regulator protein, ROK family RHE_CH01552 159 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 86357196 Common - probable glycosyltransferase protein RHE_CH01559 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 86355732 Common - hypothetical protein RHE_CH00071 6 None None None 86357588 Nonpathogen - hypothetical protein RHE_CH01968 2 None None None 86356235 Common - putative arsenate reductase (phosphatase) protein RHE_CH00583 68 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 86357585 Common ccsA cytochrome-c-type biogenesis protein RHE_CH01964 161 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 86358519 Common cinI N-acyl-L-homoserine lactone (AHL) synthase protein RHE_CH02916 24 COG3916 LasI, N-acyl-L-homoserine lactone synthetase Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 86357219 Nonpathogen - hypothetical protein RHE_CH01582 3 None None None 86356637 Nonpathogen - hypothetical protein RHE_CH00991 1 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 86356932 Common cycL cytochrome-c-type biogenesis protein RHE_CH01292 83 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 86357448 Common - probable beta-N-acetylhexosaminidase protein RHE_CH01820 168 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 86359461 Common - hypothetical protein RHE_CH03880 49 COG3735 COG3735, Uncharacterized protein conserved in bacteria Function unknown 86355776 Common infB translation initiation factor IF-2 RHE_CH00116 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 86358033 Common - probable amino acid ABC transporter, permease protein RHE_CH02420 173 COG4160 ArtM, ABC-type arginine/histidine transport system, permease component Amino acid transport and metabolism 86357234 Common btuE glutathione peroxidase protein RHE_CH01597 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 86358091 Common fnrNch transcriptional regulator protein, Fnr/CRP family RHE_CH02479 132 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 86359468 Common sucB dihydrolipoamide acetyltransferase RHE_CH03887 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 86357417 Common rbsBch2 ribose ABC transporter, substrate-binding protein RHE_CH01787 80 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86357785 Common - putative transglutaminase-like protein RHE_CH02168 76 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 86359110 Common - putative methyl-accepting chemotaxis protein RHE_CH03519 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 86357710 Common glmS1 D-fructose-6-phosphate amidotransferase RHE_CH02091 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 86358935 Common - hypothetical protein RHE_CH03337 22 COG5400 COG5400, Uncharacterized protein conserved in bacteria Function unknown 86357453 Common tatC SEC-independent protein translocase protein RHE_CH01825 204 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 86358318 Common znuA zinc uptake ABC transporter, substrate-binding protein RHE_CH02712 150 COG4531 ZnuA, ABC-type Zn2+ transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 86357849 Common - hypothetical protein RHE_CH02234 33 COG5387 COG5387, Chaperone required for the assembly of the mitochondrial F1-ATPase Posttranslational modification, protein turnover, chaperones 86359131 Common - hypothetical protein RHE_CH03540 13 None None None 86358691 Common - beta amino acid--pyruvate transaminase RHE_CH03090 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 86357439 Common valS valyl-tRNA synthetase RHE_CH01811 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 86358772 Common - probable transcriptional regulator protein RHE_CH03171 46 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 86357259 Common - probable lipoprotein ABC transporter, ATP-binding protein RHE_CH01625 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 86356561 Nonpathogen - putative oxidoreductase protein RHE_CH00915 1 None None None 86359506 Common - putative amino acid efflux protein, LysE family RHE_CH03926 114 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 86358099 Common - hypothetical protein RHE_CH02487 137 COG0730 COG0730, Predicted permeases General function prediction only 86356505 Common - probable ATP-binding protein (Mrp protein-like) RHE_CH00859 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 86358341 Nonpathogen - hypothetical protein RHE_CH02736 2 None None None 86357314 Common rpsQ 30S ribosomal protein S17 RHE_CH01684 222 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 86357800 Common pyrG CTP synthetase RHE_CH02184 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 86358310 Nonpathogen - hypothetical protein RHE_CH02704 1 None None None 86359073 Common ruvB Holliday junction DNA helicase B RHE_CH03482 227 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 86358996 Nonpathogen - hypothetical protein RHE_CH03404 1 None None None 86357669 Common - hypothetical protein RHE_CH02050 20 COG3828 COG3828, Uncharacterized protein conserved in bacteria Function unknown 86356658 Common - hypothetical protein RHE_CH01012 31 COG3011 COG3011, Uncharacterized protein conserved in bacteria Function unknown 86356638 Common - probable transcriptional regulator protein, ArsR family RHE_CH00992 33 COG0640 ArsR, Predicted transcriptional regulators Transcription 86358264 Common - probable sugar ABC transporter, permease protein RHE_CH02658 154 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 86357612 Nonpathogen - hypothetical protein RHE_CH01992 1 None None None 86357112 Common - hypothetical protein RHE_CH01474 19 COG5516 COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding General function prediction only 86356605 Common - hypothetical protein RHE_CH00959 25 COG5349 COG5349, Uncharacterized protein conserved in bacteria Function unknown 86355772 Common rpsO 30S ribosomal protein S15 RHE_CH00112 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 86356667 Common aas acylglycerophosphoethanolamine acyltransferase RHE_CH01022 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 86358359 Common - putative transcriptional regulator protein, DeoR family RHE_CH02754 67 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 86359055 Common tolA probable signal peptide protein RHE_CH03464 15 COG5373 COG5373, Predicted membrane protein Function unknown 86358100 Common cobO cob(I)yrinic acid a,c-diamide adenosyltransferase RHE_CH02488 138 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 86358508 Common - probable hydantoin racemase protein RHE_CH02905 43 COG4126 COG4126, Hydantoin racemase Amino acid transport and metabolism 86358501 Common - probable sugar ABC transporter, substrate-binding protein RHE_CH02898 73 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86358899 Common ureG urease accessory protein RHE_CH03300 153 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 86359406 Common - putative transcriptional regulator protein RHE_CH03823 11 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 86357503 Common aatCch aminotransferase RHE_CH01877 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 86355733 Common - putative cellulase H precursor protein RHE_CH00072 20 COG4124 ManB, Beta-mannanase Carbohydrate transport and metabolism 86359548 Common - putative two-component response regulator protein RHE_CH03968 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 86359066 Common - hypothetical protein RHE_CH03475 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 86358607 Common cspA5 cold shock protein RHE_CH03005 178 COG1278 CspC, Cold shock proteins Transcription 86359563 Common - hypothetical protein RHE_CH03984 18 COG3828 COG3828, Uncharacterized protein conserved in bacteria Function unknown 162329636 Common ftsZ2 cell division protein FtsZ RHE_CH02840 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 86358011 Common glpKch1 glycerol kinase protein RHE_CH02396 177 COG0554 GlpK, Glycerol kinase Energy production and conversion 86357989 Common - putative multidrug resistance ABC transporter, ATP-binding and permease protein RHE_CH02374 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 86359092 Common phzF phenazine biosynthesis protein RHE_CH03501 121 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 86359311 Common - putative dehydrogenase protein RHE_CH03721 88 COG2081 COG2081, Predicted flavoproteins General function prediction only 86358769 Common - hypothetical protein RHE_CH03168 16 COG4907 COG4907, Predicted membrane protein Function unknown 86359498 Nonpathogen - hypothetical protein RHE_CH03917 1 None None None 86358673 Common - 7-cyano-7-deazaguanine reductase RHE_CH03071 121 COG0780 COG0780, Enzyme related to GTP cyclohydrolase I General function prediction only 86359380 Common lysA diaminopimelate decarboxylase protein RHE_CH03797 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 86355723 Common actR two-component response regulator protein RHE_CH00055 218 COG4567 COG4567, Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain Signal transduction mechanisms / Transcription 86357410 Common narB nitrate reductase large subunit protein RHE_CH01780 187 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 86357254 Common - putative metallo-beta-lactamase family protein RHE_CH01620 155 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 86357397 Common - hypothetical protein RHE_CH01767 3 None None None 86357248 Common nuoJ NADH dehydrogenase subunit J RHE_CH01614 67 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 86356130 Common pyrE orotate phosphoribosyltransferase RHE_CH00474 168 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 86357298 Common rpoC DNA-directed RNA polymerase subunit beta' RHE_CH01668 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 86357138 Nonpathogen - hypothetical protein RHE_CH01500 1 None None None 86358373 Common pdxJ pyridoxal phosphate biosynthetic protein PdxJ RHE_CH02769 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 86356618 Common - probable molybdate ABC transporter, substrate-binding protein RHE_CH00972 34 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 86358075 Common - hypothetical protein RHE_CH02463 4 None None None 86357899 Common - probable transcriptional regulator protein, GntR family RHE_CH02284 178 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 86357169 Common plsX fatty acid/phospholipid synthesis protein RHE_CH01531 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 86355708 Common coaA pantothenate kinase RHE_CH00040 79 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 86356946 Common - putative aminoglycoside phosphotransferase protein (antibiotic resistance protein) RHE_CH01306 5 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 86357128 Common - hypothetical protein RHE_CH01490 68 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 86357273 Common - probable DNA processing chain A protein RHE_CH01639 206 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 86356046 Common tme malic enzyme RHE_CH00389 215 COG0281 SfcA, Malic enzyme Energy production and conversion 86357606 Nonpathogen - hypothetical protein RHE_CH01986 1 None None None 86356689 Common - hypothetical protein RHE_CH01045 15 COG5397 COG5397, Uncharacterized conserved protein Function unknown 86357782 Common - probable transcriptional regulator protein, TetR family RHE_CH02165 31 COG1309 AcrR, Transcriptional regulator Transcription 86359370 Common - putative ribonuclease protein RHE_CH03787 78 COG1295 Rbn, Predicted membrane protein Function unknown 86356510 Common atpB F0F1 ATP synthase subunit A RHE_CH00864 200 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 86359482 Common - YciI-like protein RHE_CH03901 79 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 86359350 Common mutT NTP pyrophosphohydrolase protein RHE_CH03766 135 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 86355795 Common - probable sugar kinase protein RHE_CH00135 141 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 86358131 Common - putative copper-containing oxidase protein RHE_CH02520 32 COG4454 COG4454, Uncharacterized copper-binding protein Inorganic ion transport and metabolism 162329626 Common atpG F0F1 ATP synthase subunit gamma RHE_CH03871 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 86358141 Common - probable transcriptional regulator protein, ArsR family RHE_CH02531 68 COG0640 ArsR, Predicted transcriptional regulators Transcription 86356549 Nonpathogen - hypothetical protein RHE_CH00903 1 None None None 86356621 Common - hypothetical protein RHE_CH00975 5 None None None 86357123 Common - putative ADP-ribose pyrophosphatase protein RHE_CH01485 161 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 86356575 Common bioN biotin transporter, permease protein RHE_CH00929 52 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 86359377 Common hbdA 3-hydroxybutyryl-CoA dehydrogenase RHE_CH03794 161 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 86356985 Common - probable oxidoreductase protein RHE_CH01346 180 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 86357456 Common pcm protein-L-isoaspartate O-methyltransferase RHE_CH01828 154 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 86358331 Common - putative hydrolase protein RHE_CH02726 43 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 86356907 Nonpathogen - hypothetical protein RHE_CH01267 1 None None None 86356978 Common - hypothetical protein RHE_CH01338 9 None None None 86357147 Common - hypothetical protein RHE_CH01509 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 86356340 Common - hypothetical protein RHE_CH00689 11 COG3951 COG3951, Rod binding protein Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 86355973 Common - probable phosphatidylethanolamine N-methyltransferase/phosphatidyl-N-methylethanolamineN-methyltransferase protein RHE_CH00316 39 COG3963 COG3963, Phospholipid N-methyltransferase Lipid metabolism 86355683 Common - hypothetical protein RHE_CH00014 18 COG3553 COG3553, Uncharacterized protein conserved in bacteria Function unknown 86357205 Common speB1 agmatinase protein RHE_CH01568 133 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 86358064 Common hndI multidrug ABC transporter, ATP-binding protein RHE_CH02452 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 86357099 Common - hypothetical protein RHE_CH01461 50 COG2079 PrpD, Uncharacterized protein involved in propionate catabolism General function prediction only 86356855 Common cycG diheme cytochrome-c-type signal peptide protein RHE_CH01215 53 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 86355946 Common - short chain dehydrogenase RHE_CH00289 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 86359576 Common ndvB beta-1,2-glucan production associated transmembrane protein RHE_CH03997 47 COG3459 COG3459, Cellobiose phosphorylase Carbohydrate transport and metabolism 86356850 Common - probable sugar ABC transporter, substrate-binding protein RHE_CH01210 116 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86356285 Common - hypothetical protein RHE_CH00634 12 COG1709 COG1709, Predicted transcriptional regulator Transcription 86356352 Common - hypothetical protein RHE_CH00701 3 None None None 86358749 Common - probable transporter protein RHE_CH03148 204 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86357954 Common - hypothetical protein RHE_CH02339 11 COG2198 ArcB, FOG: HPt domain Signal transduction mechanisms 86357546 Common lpxB lipid-A-disaccharide synthase RHE_CH01925 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 86359164 Common - probable monophosphatase protein RHE_CH03573 181 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 86357500 Common - hypothetical protein RHE_CH01874 11 None None None 86358058 Common - hypothetical protein RHE_CH02446 54 COG3577 COG3577, Predicted aspartyl protease General function prediction only 86359192 Common soxDch sarcosine oxidase delta subunit protein RHE_CH03602 31 COG4311 SoxD, Sarcosine oxidase delta subunit Amino acid transport and metabolism 86357554 Common pdhA1 pyruvate dehydrogenase alpha subunit protein RHE_CH01933 164 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 86357747 Common drrA two-component response regulator protein RHE_CH02128 208 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 86356756 Nonpathogen - hypothetical protein RHE_CH01114 1 None None None 86359283 Common araH L-arabinose transporter permease protein RHE_CH03693 136 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 86358460 Common - probable sarcosine oxidase protein RHE_CH02857 23 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 86358473 Common - putative permease protein RHE_CH02870 130 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 86357511 Common - hypothetical protein RHE_CH01890 36 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 86358020 Common - hypothetical conserved membrane protein RHE_CH02405 44 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 86358527 Common - hypothetical protein RHE_CH02925 2 None None None 86356171 Common argF ornithine carbamoyltransferase RHE_CH00517 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 86357523 Common - probable hydrolase protein RHE_CH01902 157 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 86359551 Common - putative outer membrane lipoproteins carrier protein RHE_CH03971 37 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 86356312 Common flgG flagellar basal body rod protein FlgG RHE_CH00661 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 86357304 Common rpsJ 30S ribosomal protein S10 RHE_CH01674 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 86357778 Common tmk thymidylate kinase protein RHE_CH02160 235 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 86356361 Common - probable transcriptional regulator protein RHE_CH00710 44 COG0583 LysR, Transcriptional regulator Transcription 86359612 Common metA homoserine O-succinyltransferase RHE_CH04033 64 COG1897 MetA, Homoserine trans-succinylase Amino acid transport and metabolism 86357008 Common exoF1 exopolysaccharide biosynthesis protein (OMA family outer membrane saccharide export protein) RHE_CH01370 34 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 86357975 Common - probable sugar ABC transporter, permease protein RHE_CH02360 126 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 86359531 Common - hypothetical protein RHE_CH03951 11 None None None 86359325 Common nuoN2 NADH-ubiquinone oxidoreductase chain N protein RHE_CH03735 210 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 86358510 Common - probable spermidine/putrescine ABC transporter, permease protein RHE_CH02907 188 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 86357193 Common - probable sugar ABC transporter, permease protein RHE_CH01556 165 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 86357623 Nonpathogen - hypothetical protein RHE_CH02003 1 None None None 86358742 Common - hypothetical protein RHE_CH03141 47 COG3195 COG3195, Uncharacterized protein conserved in bacteria Function unknown 86356038 Common nifUch1 nitrogen fixation protein RHE_CH00381 91 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 86357473 Common - soluble pyridine nucleotide transhydrogenase RHE_CH01846 245 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 86356499 Common kdgA 2-dehydro-3-deoxy-6-phosphogalactonate aldolase RHE_CH00853 124 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 86356127 Common - hypothetical protein RHE_CH00471 17 None None None 86358290 Common - probable adenylate cyclase protein RHE_CH02684 76 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 86357970 Common dme malic enzyme RHE_CH02355 210 COG0281 SfcA, Malic enzyme Energy production and conversion 86358113 Common greB transcription elongation factor regulatory protein RHE_CH02501 129 COG0782 GreA, Transcription elongation factor Transcription 86356672 Common - putative transcriptional regulator protein RHE_CH01028 144 COG1733 COG1733, Predicted transcriptional regulators Transcription 86359176 Common cyaFch2 adenylate cyclase protein RHE_CH03586 85 COG5616 COG5616, Predicted integral membrane protein Function unknown 86358797 Common - putative polysaccharide deacetylase/methyltransferase protein RHE_CH03197 161 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 86356739 Common - hypothetical protein RHE_CH01096 4 None None None 86359217 Common cysE2 serine acetyltransferase protein RHE_CH03627 209 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 86357163 Common ribH riboflavin synthase subunit beta RHE_CH01525 214 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 86359502 Common - hypothetical protein RHE_CH03921 8 None None None 86359519 Common - putative ABC transporter, permease protein (involved in lysophospholipase L1 biosynthesis) RHE_CH03939 86 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 86359434 Common rocD ornithine--oxo-acid transaminase RHE_CH03852 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 86356601 Common ctaG cytochrome C oxidase assembly protein RHE_CH00955 68 COG3175 COX11, Cytochrome oxidase assembly factor Posttranslational modification, protein turnover, chaperones 86358762 Common - probable aldehyde dehydrogenase protein RHE_CH03161 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 86358345 Common - putative phosphoglycerate mutase protein RHE_CH02740 97 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 86358823 Common - hypothetical protein RHE_CH03224 11 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 86355676 Common fxsA FxsA RHE_CH00007 69 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 86355875 Common - probable transcriptional regulator protein, MarR family RHE_CH00216 16 COG1846 MarR, Transcriptional regulators Transcription 86355810 Common - probable transcriptional regulator protein, MarR family RHE_CH00150 113 COG1846 MarR, Transcriptional regulators Transcription 86358925 Common pssB exopolysaccharide production protein RHE_CH03327 189 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 86359675 Common - putative ABC transporter, ATP-binding protein RHE_CH04097 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 86359107 Common cheRch2 chemotaxis methyltransferase protein RHE_CH03516 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 86356519 Common ispE 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase protein RHE_CH00873 175 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 86359448 Common - putative acyltransferase protein RHE_CH03867 2 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 86358595 Common chaA LPS-associated cation exporter (Ca2+/H+ antiporter) protein RHE_CH02993 57 COG0387 ChaA, Ca2+/H+ antiporter Inorganic ion transport and metabolism 86357929 Common murI glutamate racemase RHE_CH02314 189 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 86356389 Common dppF dipeptide transporter ATP-binding subunit RHE_CH00740 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 86357084 Common - hypothetical protein RHE_CH01446 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 86359604 Common - probable transcriptional regulator protein, CarD family RHE_CH04025 84 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 86357162 Nonpathogen - hypothetical protein RHE_CH01524 2 None None None 86359100 Common - hypothetical protein RHE_CH03509 34 COG3422 COG3422, Uncharacterized conserved protein Function unknown 86355716 Common hslV ATP-dependent protease peptidase subunit RHE_CH00048 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 86359042 Common rapB3 autoaggregation protein (adhering protein) RHE_CH03450 17 None None None 86356926 Common feuP two-component response regulator protein RHE_CH01286 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 86359257 Common tal transaldolase B RHE_CH03667 186 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 86357607 Common - putative integrase protein RHE_CH01987 21 None None None 86358077 Common - hypothetical protein RHE_CH02465 33 COG3911 COG3911, Predicted ATPase General function prediction only 86356456 Common glcF glycolate oxidase subunit F protein RHE_CH00810 180 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 86356468 Common hisZ ATP phosphoribosyltransferase regulatory subunit RHE_CH00822 85 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 86358804 Common - hypothetical protein RHE_CH03204 25 COG3482 COG3482, Uncharacterized conserved protein Function unknown 86358838 Common - probable serine/threonine specific protein phosphatase protein RHE_CH03239 85 COG0639 ApaH, Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Signal transduction mechanisms 86358890 Common - hypothetical protein RHE_CH03291 48 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 86355963 Common - probable rare lipoprotein A protein RHE_CH00306 124 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 86358085 Common msbB lipid A biosynthesis lauroyl acyltransferase RHE_CH02473 71 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 86358668 Common - hypothetical protein RHE_CH03066 24 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 86359550 Common xthA3 exodeoxyribonuclease III protein RHE_CH03970 193 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 86355761 Nonpathogen - hypothetical protein RHE_CH00101 1 None None None 86358578 Common - probable transcriptional regulator protein, LysR family RHE_CH02976 190 COG0583 LysR, Transcriptional regulator Transcription 86357641 Nonpathogen - hypothetical protein RHE_CH02022 1 None None None 86357797 Common - putative adenylate cyclase protein RHE_CH02180 75 COG4252 COG4252, Predicted transmembrane sensor domain Signal transduction mechanisms 86356657 Common - hypothetical protein RHE_CH01011 11 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 86358711 Common - putative nitrate reductase protein RHE_CH03110 33 COG4094 COG4094, Predicted membrane protein Function unknown 86357045 Common - putative ADP-ribose pyrophosphatase protein, mutT/nudiX family RHE_CH01407 81 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 86358225 Common - probable cytochrome-c protein RHE_CH02618 55 COG3474 COG3474, Cytochrome c2 Energy production and conversion 86358251 Common - putative sensory box/GGDEF family protein RHE_CH02645 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 86358261 Nonpathogen - putative insertion sequence transposase protein RHE_CH02655 6 None None None 86358045 Common ssuD alkanesulfonate monooxygenase protein RHE_CH02432 69 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 86357102 Common - probable amino acid ABC transporter, permease protein RHE_CH01464 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 86358070 Common - probable sugar ABC transporter, ATP-binding protein RHE_CH02458 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 86355756 Common rnd1 RNAse D protein RHE_CH00095 108 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 86359182 Common - hypothetical protein RHE_CH03592 12 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 86357917 Common - hypothetical protein RHE_CH02302 12 None None None 86356508 Common - putative cell wall hydrolase protein involved in spore germination RHE_CH00862 47 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 86359123 Common purK phosphoribosylaminoimidazole carboxylase ATPase subunit RHE_CH03532 194 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 86355742 Common - probable transcriptional regulator protein, TetR family RHE_CH00081 116 COG1309 AcrR, Transcriptional regulator Transcription 86359076 Common atvA acid tolerance and virulence protein RHE_CH03485 19 COG3946 VirJ, Type IV secretory pathway, VirJ component Intracellular trafficking and secretion 86356460 Common - hypothetical protein RHE_CH00814 88 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 86356965 Common - hypothetical protein RHE_CH01325 45 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 86357268 Common rpmG 50S ribosomal protein L33 RHE_CH01634 113 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 86358788 Common - probable acetyltransferase protein RHE_CH03188 8 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 86355932 Common - probable glycosyltransferase protein RHE_CH00274 107 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 86356939 Common - putative permease protein RHE_CH01299 94 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 86357203 Common - hypothetical conserved membrane protein RHE_CH01566 29 None None None 86359000 Common - probable cation transporter protein RHE_CH03408 105 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 86357096 Common gal D-galactose-1-dehydrogenase protein RHE_CH01458 141 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 86359222 Common - putative nickel ABC transporter, permease protein RHE_CH03632 36 COG2215 COG2215, ABC-type uncharacterized transport system, permease component General function prediction only 86359339 Common hemK protoporphyrinogen oxidase (methyltransferase) protein RHE_CH03755 224 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 86356344 Nonpathogen - putative succinoglycan biosynthesis transport protein RHE_CH00693 1 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 162329638 Common aroEch2 shikimate 5-dehydrogenase RHE_CH02291 212 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 86359697 Common parB chromosome partitioning protein B RHE_CH04119 189 COG1475 Spo0J, Predicted transcriptional regulators Transcription 86359207 Common - putative TRAP mannitol/C4-dicarboxylate transporter, permease protein RHE_CH03617 73 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 86356006 Common - hypothetical protein RHE_CH00349 11 COG3535 COG3535, Uncharacterized conserved protein Function unknown 86356899 Common - hypothetical conserved membrane protein RHE_CH01259 12 COG5436 COG5436, Predicted integral membrane protein Function unknown 86356017 Common hemNch coproporphyrinogen III oxidase RHE_CH00360 213 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 86356776 Nonpathogen - hypothetical protein RHE_CH01134 7 None None None 86357855 Common - hypothetical protein RHE_CH02240 4 None None None 86356218 Common - probable transcriptional regulator protein, TetR family RHE_CH00565 30 COG1309 AcrR, Transcriptional regulator Transcription 86358138 Nonpathogen - hypothetical protein RHE_CH02528 1 None None None 86359361 Nonpathogen - hypothetical protein RHE_CH03778 2 None None None 86356288 Common - hypothetical protein RHE_CH00637 7 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 86357145 Common - putative peptidoglycan binding protein (involved in cell wall degradation) RHE_CH01507 74 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 86357796 Common deaD ATP-dependent RNA helicase protein RHE_CH02179 238 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 86355851 Common deoD purine nucleoside phosphorylase RHE_CH00192 159 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 86357392 Common - probable oxidoreductase protein RHE_CH01762 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 86358604 Common - putative glucose dehydrogenase B protein RHE_CH03002 121 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 86356443 Common - probable dehydrogenase protein RHE_CH00797 232 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 86359663 Common - hypothetical protein RHE_CH04085 8 COG4544 COG4544, Uncharacterized conserved protein Function unknown 86358998 Common - probable pseudouridylate synthase, ribosomal large subunit protein RHE_CH03406 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 86358191 Common - putative methyltransferase protein RHE_CH02583 81 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 86359528 Common ccmC heme ABC transporter, permease protein (involved in cytochrome-c biogenesis) RHE_CH03948 129 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 86359457 Common - probable dihydrodipicolinate synthase protein RHE_CH03876 185 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 86357176 Common - hypothetical protein RHE_CH01538 3 None None None 86356815 Common - probable transcriptional regulator protein, MarR family RHE_CH01175 39 COG1846 MarR, Transcriptional regulators Transcription 86359644 Nonpathogen - putative endonuclease/exonuclease/phosphatase protein RHE_CH04066 6 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 86358542 Common - probable transcriptional regulator protein, Fnr/CRP family RHE_CH02940 66 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 86356789 Common gstch6 glutathione S-transferase protein RHE_CH01147 91 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 86359015 Nonpathogen - hypothetical protein RHE_CH03423 1 None None None 86357732 Common coaD phosphopantetheine adenylyltransferase RHE_CH02113 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 86356590 Common dacF1 D-alanyl-D-alanine carboxypeptidase protein RHE_CH00944 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 86356729 Common aacC1 aminoglycoside N3`-acetyltransferase protein RHE_CH01086 22 COG2746 COG2746, Aminoglycoside N3'-acetyltransferase Defense mechanisms 86358188 Common - probable dihydrofolate reductase protein RHE_CH02579 30 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 86359010 Common potA spermidine/putrescine ABC transporter, ATP-binding protein RHE_CH03418 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 86357693 Common - putative protein secretion protein, HylD family RHE_CH02074 168 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 86357285 Common ppnK inorganic polyphosphate/ATP-NAD kinase RHE_CH01651 233 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 86358295 Common - putative glyoxalase protein RHE_CH02689 17 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 86355928 Common - probable acetyltransferase protein RHE_CH00270 100 COG0456 RimI, Acetyltransferases General function prediction only 86356999 Common - hypothetical protein RHE_CH01361 4 COG4641 COG4641, Uncharacterized protein conserved in bacteria Function unknown 86359652 Common modE molybdenum-binding transcriptional regulator-repressor protein (molybdenum transport associatedprotein) RHE_CH04074 91 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 86358155 Common - hypothetical protein RHE_CH02546 37 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 86357535 Common tsf elongation factor Ts RHE_CH01914 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 86356892 Common - probable two-component sensor histidine kinase protein RHE_CH01252 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 86357337 Common degPch3 serine protease DO-like protein RHE_CH01707 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 86359270 Common smoG sorbitol/mannitol ABC transporter, permease protein RHE_CH03680 166 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 86358553 Common tdh L-threonine 3-dehydrogenase RHE_CH02951 213 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 86359267 Common - probable hydrolase phosphatase protein RHE_CH03677 146 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 86357327 Common rpsM 30S ribosomal protein S13 RHE_CH01697 244 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 86358364 Common ndhch NADH dehydrogenase protein RHE_CH02760 191 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 86357933 Nonpathogen icd NADP-dependent isocitrate dehydrogenase protein RHE_CH02318 1 None None None 86356321 Common flaCch2 flagellin C protein RHE_CH00670 108 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 86358181 Nonpathogen - hypothetical protein RHE_CH02572 1 COG4907 COG4907, Predicted membrane protein Function unknown 86359011 Common - probable inosine-uridine preferring nucleoside hydrolase protein RHE_CH03419 81 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 86358983 Common exoY exopolysaccharide production protein RHE_CH03385 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 86357630 Common - putative insertion sequence transposase protein RHE_CH02010 19 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 86359245 Common - probable transporter protein, TerC family RHE_CH03655 114 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 86356202 Common lhr ATP-dependent RNA/DNA helicase protein RHE_CH00549 224 COG1201 Lhr, Lhr-like helicases General function prediction only 86356792 Common - putative ABC transporter, ATP-binding protein RHE_CH01150 249 COG4586 COG4586, ABC-type uncharacterized transport system, ATPase component General function prediction only 86358915 Common - probable urea or short-chain amide ABC transporter, permease protein RHE_CH03316 164 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 86358843 Common noeJ mannose-1-phosphate guanylyltransferase (GDP) protein RHE_CH03244 164 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 86358383 Common rpoE2 RNA polymerase sigma factor protein (sigma-24) RHE_CH02779 149 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 86359492 Common - hypothetical conserved membrane protein RHE_CH03911 40 COG0762 COG0762, Predicted integral membrane protein Function unknown 86356990 Common - probable glycosyltransferase protein RHE_CH01352 213 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 86357260 Common - hypothetical protein RHE_CH01626 3 None None None 86355843 Nonpathogen - hypothetical protein RHE_CH00183 1 None None None 86358376 Common - putative transcriptional regulator protein, LysR family RHE_CH02772 101 COG0583 LysR, Transcriptional regulator Transcription 86357750 Nonpathogen - hypothetical protein RHE_CH02131 1 None None None 86358150 Common - probable transporter protein RHE_CH02540 207 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86355693 Common trxA1 thioredoxin protein RHE_CH00025 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 86358888 Common - probable transcriptional regulator protein, TetR family RHE_CH03289 125 COG1309 AcrR, Transcriptional regulator Transcription 86357089 Common - probable peptidyl-prolyl cis-trans isomerase protein RHE_CH01451 41 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 86358851 Common - probable ABC transporter, permease protein RHE_CH03252 149 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 86359332 Common nuoG2 NADH-ubiquinone oxidoreductase chain G protein RHE_CH03742 207 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 86356487 Common pmbA modulator of DNA gyrase protein RHE_CH00841 159 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 86359260 Common - hypothetical protein RHE_CH03670 20 COG5488 COG5488, Integral membrane protein Function unknown 86356431 Common - probable insertion sequence transposase protein, IS1111A/IS1328/IS1533 family RHE_CH00782 104 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 86356848 Common - hypothetical protein RHE_CH01208 43 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 86356392 Common - hypothetical protein RHE_CH00743 17 COG1755 COG1755, Uncharacterized protein conserved in bacteria Function unknown 86358520 Common - probable two-component response regulator protein RHE_CH02917 88 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 86356934 Common ragA two-component response regulator protein RHE_CH01294 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 86358654 Common - putative methanol dehydrogenase regulator MoxR-like protein RHE_CH03052 174 COG0714 COG0714, MoxR-like ATPases General function prediction only 86358006 Common - hypothetical protein RHE_CH02391 51 COG3536 COG3536, Uncharacterized protein conserved in bacteria Function unknown 86357637 Nonpathogen - hypothetical protein RHE_CH02017 3 None None None 162329642 Common proS prolyl-tRNA synthetase RHE_CH01623 249 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 86359201 Common pntB NAD(P)(+) transhydrogenase (AB-specific), beta subunit protein RHE_CH03611 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 86357365 Common - probable two-component sensor histidine kinase protein RHE_CH01735 127 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 86358670 Common - probable benzoate transporter protein RHE_CH03068 59 COG3135 BenE, Uncharacterized protein involved in benzoate metabolism Secondary metabolites biosynthesis, transport, and catabolism 86358813 Common pssR acetyltransferase protein RHE_CH03214 167 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 86359158 Nonpathogen - hypothetical protein RHE_CH03567 1 None None None 86356022 Common grpE molecular chaperone heat shock protein (hsp-70) RHE_CH00365 230 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 86357371 Common - hypothetical protein RHE_CH01741 75 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 86358179 Common - probable serine protease protein, HtrA/DegQ family RHE_CH02570 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 86355830 Common dapB1 dihydrodipicolinate reductase RHE_CH00170 216 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 86357061 Common - hypothetical protein RHE_CH01423 64 COG3791 COG3791, Uncharacterized conserved protein Function unknown 86359219 Common - probable ornithine decarboxylase protein RHE_CH03629 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 86356909 Common - hypothetical protein RHE_CH01269 10 None None None 86359588 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase RHE_CH04009 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 86358905 Common - probable urease-associated protein RHE_CH03306 7 None None None 86356888 Nonpathogen - hypothetical protein RHE_CH01248 1 None None None 86357619 Nonpathogen - hypothetical protein RHE_CH01999 1 None None None 86357712 Common recG ATP-dependent DNA helicase protein RHE_CH02093 214 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 86357063 Common cysS cysteinyl-tRNA synthetase RHE_CH01425 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 86356052 Common - putative hydrolase protein, MutT/nudix family RHE_CH00395 17 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 86358940 Common rpoH1 RNA polymerase factor sigma-32 RHE_CH03342 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 86359599 Nonpathogen - hypothetical protein RHE_CH04020 1 None None None 86356094 Common - putative inner membrane protein translocase component YidC RHE_CH00437 215 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 86358764 Common gguB xylose ABC transporter, permease protein RHE_CH03163 108 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 86356323 Common flaCch4 flagellin C protein RHE_CH00672 86 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 86357598 Nonpathogen - hypothetical protein RHE_CH01978 1 None None None 86357119 Common ropB1 outer membrane protein RHE_CH01481 22 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 86357568 Common ntrB nitrogen regulation (two-component sensor histidine kinase) protein RHE_CH01947 221 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 86358517 Nonpathogen - hypothetical protein RHE_CH02914 1 None None None 86356635 Nonpathogen - hypothetical protein RHE_CH00989 3 None None None 86356554 Common - short chain dehydrogenase RHE_CH00908 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 86358957 Common - probable Na+/H+ antiporter protein RHE_CH03359 98 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 86355978 Common - hypothetical protein RHE_CH00321 20 COG3450 COG3450, Predicted enzyme of the cupin superfamily General function prediction only 86359235 Common - probable sugar ABC transporter, permease protein RHE_CH03645 114 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 86355801 Common recF recombination protein F RHE_CH00141 166 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 86356754 Nonpathogen - hypothetical protein RHE_CH01112 1 None None None 86358939 Common rluD pseudouridylate synthase, ribosomal large subunit D protein RHE_CH03341 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 86358161 Common - probable SAM-dependent methyltransferase protein RHE_CH02552 80 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 86357032 Common recO DNA repair protein RecO RHE_CH01394 63 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 86355996 Common - probable cyanate transport protein RHE_CH00339 74 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 86356014 Common rpsT 30S ribosomal protein S20 RHE_CH00357 120 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 86358168 Common - hypothetical protein RHE_CH02559 26 COG4312 COG4312, Uncharacterized protein conserved in bacteria Function unknown 86355808 Common dapE1 hypothetical protein RHE_CH00148 170 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 86357578 Common - probable deoxycytidylate deaminase family protein RHE_CH01957 14 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 86359180 Common - hypothetical protein RHE_CH03590 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 86356157 Common - hypothetical protein RHE_CH00502 2 None None None 86357825 Common - hypothetical protein RHE_CH02209 16 COG3672 COG3672, Predicted periplasmic protein Function unknown 86359057 Common tolQ protein transporter protein RHE_CH03466 148 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 86356919 Common - putative pyridoxine 5`-phosphate oxidase protein RHE_CH01279 46 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 86358841 Common ung uracil-DNA glycosylase RHE_CH03242 128 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 86359247 Common lysS lysyl-tRNA synthetase protein RHE_CH03657 246 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 86357838 Common lipB lipoyltransferase RHE_CH02223 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 86358466 Common - probable amino acid efflux protein, LysE family RHE_CH02863 124 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 86359068 Common - probable methyl-accepting chemotaxis protein RHE_CH03477 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 86356459 Common - hypothetical protein RHE_CH00813 85 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 86359320 Common nuoK2 NADH-ubiquinone oxidoreductase chain K protein RHE_CH03730 12 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 86357107 Common - hypothetical protein RHE_CH01469 175 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 86359622 Common - acyl carrier protein RHE_CH04043 7 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 86357675 Common - probable sugar ABC transporter, ATP-binding protein RHE_CH02056 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 86357348 Nonpathogen - hypothetical protein RHE_CH01718 1 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 86359151 Common - hypothetical protein RHE_CH03560 18 COG5338 COG5338, Uncharacterized protein conserved in bacteria Function unknown 86358245 Common - putative intracellular protease/amidase protein RHE_CH02638 95 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 86356874 Common - putative hemolysin III protein RHE_CH01234 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 86356828 Common - hypothetical protein RHE_CH01188 4 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 86359255 Common - hypothetical conserved membrane protein RHE_CH03665 9 COG2259 COG2259, Predicted membrane protein Function unknown 86358212 Common plyA1 polysaccharidase protein RHE_CH02605 26 None None None 86359203 Common pntA2 NAD(P)(+) transhydrogenase (AB-specific), alpha subunit protein RHE_CH03613 166 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 86356582 Common - hypothetical protein RHE_CH00936 6 None None None 86359425 Common - putative sugar ABC transporter, permease protein RHE_CH03843 147 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 86357143 Common - hypothetical protein RHE_CH01505 13 None None None 86356683 Nonpathogen - hypothetical protein RHE_CH01039 2 None None None 86356450 Common - hypothetical protein RHE_CH00804 178 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 86357909 Common - probable amino acid ABC transporter, permease protein RHE_CH02294 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 86359033 Common ackA acetate kinase RHE_CH03441 161 COG0282 ackA, Acetate kinase Energy production and conversion 86359308 Common nrdH glutaredoxin protein RHE_CH03718 34 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 86355779 Common - hypothetical protein RHE_CH00119 163 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 86358659 Common - probable insertion sequence transposase protein RHE_CH03057 52 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 86355985 Common - probable transcriptional regulator protein, AsnC family RHE_CH00328 140 COG1522 Lrp, Transcriptional regulators Transcription 86355709 Common hisE phosphoribosyl-ATP pyrophosphatase RHE_CH00041 179 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 86358683 Common - hypothetical protein RHE_CH03082 23 COG5345 COG5345, Uncharacterized protein conserved in bacteria Function unknown 86356427 Common - probable insertion sequence transposase protein RHE_CH00778 59 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 86355987 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase RHE_CH00330 182 COG0756 Dut, dUTPase Nucleotide transport and metabolism 86359054 Common - putative signal peptide protein RHE_CH03463 5 None None None 86358826 Common - putative acyl-CoA thioesterase/lipase protein RHE_CH03227 18 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 86358104 Common clc chloride channel protein RHE_CH02492 157 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 86359229 Common - putative sensory box/GGDEF family protein (nitrogen fixation positive activator protein-like) RHE_CH03639 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 86357023 Common relA guanosine-3`,5`-bis(diphosphate) 3`-pyrophosphohydrolase protein RHE_CH01385 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 86358652 Common - probable NTP pyrophosphohydrolase protein, MutT/nudix family RHE_CH03050 127 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 86357832 Common - hypothetical conserved membrane protein RHE_CH02216 27 COG3503 COG3503, Predicted membrane protein Function unknown 86355768 Common fabB 3-oxoacyl-(acyl carrier protein) synthase I RHE_CH00108 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 86356912 Nonpathogen - hypothetical protein RHE_CH01272 4 None None None 86359187 Common pgm phosphoglucomutase RHE_CH03597 195 COG0033 Pgm, Phosphoglucomutase Carbohydrate transport and metabolism 86358398 Common serB phosphoserine phosphatase protein RHE_CH02794 151 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 86357636 Common - putative insertion sequence transposase protein, IS66 family RHE_CH02016 24 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 86358097 Common iunH2 inosine-uridine preferring nucleoside hydrolase protein RHE_CH02485 86 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 86357283 Common - hypothetical protein RHE_CH01649 40 COG4188 COG4188, Predicted dienelactone hydrolase General function prediction only 86359337 Common clpB ATP-dependent Clp protease, ATP-binding subunit protein RHE_CH03753 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 86356704 Common - probable transcriptional regulator protein, LysR family RHE_CH01061 164 COG0583 LysR, Transcriptional regulator Transcription 86356183 Common - hypothetical protein RHE_CH00530 3 None None None 86359446 Common - putative nitrate/sulfonate/bicarbonate ABC transporter, ATP-binding protein RHE_CH03865 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 86358409 Common - probable oxidoreductase protein RHE_CH02805 200 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 86358869 Common hmuU hemin transport system, permease protein RHE_CH03270 189 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 86356226 Common uvrD1 ATP-dependent DNA helicase protein RHE_CH00573 231 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 86357198 Common - probable polysaccharide export system protein RHE_CH01561 114 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 86358183 Nonpathogen - hypothetical protein RHE_CH02574 2 COG3981 COG3981, Predicted acetyltransferase General function prediction only 86358920 Common - hypothetical protein RHE_CH03322 10 None None None 86356194 Common dinF DNA-damage-inducible F protein (Na+ driven multidrug efflux pump) RHE_CH00541 79 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 86356708 Common - probable sulfate ABC transporter, permease protein RHE_CH01065 101 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 86356726 Nonpathogen ndiA2 nutrient deprivation-induced protein RHE_CH01083 2 None None None 86356703 Common - hypothetical protein RHE_CH01060 22 COG3703 ChaC, Uncharacterized protein involved in cation transport Inorganic ion transport and metabolism 86357683 Common dppFch2 dipeptide ABC transporter, ATP-binding protein RHE_CH02064 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 86357510 Common - probable NADH-ubiquinone oxidoreductase protein RHE_CH01888 37 None None None 86357278 Common - hypothetical protein RHE_CH01644 16 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 86357057 Common leuA1 putative alpha-isopropylmalate/homocitrate synthase family transferase RHE_CH01419 213 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 86356245 Common - hypothetical conserved membrane protein RHE_CH00594 19 COG5572 COG5572, Predicted integral membrane protein Function unknown 86358533 Nonpathogen - hypothetical protein RHE_CH02931 1 None None None 86358834 Common pssN exopolysaccharide export protein RHE_CH03235 80 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 86359462 Common - putative cytochrome b561 protein RHE_CH03881 52 COG3038 CybB, Cytochrome B561 Energy production and conversion 86358339 Common - hypothetical conserved membrane protein RHE_CH02734 13 COG4244 COG4244, Predicted membrane protein Function unknown 86358787 Nonpathogen - hypothetical protein RHE_CH03187 1 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 86358362 Common - probable transcriptional regulator protein, AraC family RHE_CH02757 80 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 86358039 Common - hypothetical protein RHE_CH02426 26 COG3832 COG3832, Uncharacterized conserved protein Function unknown 86358418 Common - hypothetical protein RHE_CH02815 71 COG2719 SpoVR, Uncharacterized conserved protein Function unknown 86357485 Common - hypothetical protein RHE_CH01859 17 COG3811 COG3811, Uncharacterized protein conserved in bacteria Function unknown 86357941 Common - probable two-component sensor histidine kinase/response regulator hybrid protein RHE_CH02326 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 86358267 Common - probable transcriptional regulator protein, ROK family RHE_CH02661 170 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 86359475 Common sdhB succinate dehydrogenase iron-sulfur subunit RHE_CH03894 194 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 86357847 Common pccB propionyl-CoA carboxylase beta chain protein RHE_CH02232 214 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 86359330 Common nuoE2 NADH-ubiquinone oxidoreductase chain E protein RHE_CH03740 156 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 86358634 Nonpathogen - hypothetical protein RHE_CH03032 11 None None None 86358862 Nonpathogen - hypothetical protein RHE_CH03263 2 None None None 162329640 Common codAch2 cytosine deaminase RHE_CH02043 67 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 86357926 Common glsA glutaminase RHE_CH02311 72 COG2066 GlsA, Glutaminase Amino acid transport and metabolism 86357805 Common - putative permease protein RHE_CH02189 138 COG0628 PerM, Predicted permease General function prediction only 86358854 Common thuBch myo-inositol 2-dehydrogenase protein RHE_CH03255 152 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 86356387 Common dppCch1 dipeptide ABC transporter, permease protein RHE_CH00738 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 86357888 Common purB adenylosuccinate lyase RHE_CH02273 241 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 86355900 Common - putative recombinase protein, phage integrase family RHE_CH00241 27 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 86356690 Common - probable transcriptional regulator protein, ArsR family RHE_CH01046 30 COG0640 ArsR, Predicted transcriptional regulators Transcription 86355770 Common - probable rRNA (guanine-N2-)-methyltransferase, small subunit protein RHE_CH00110 76 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 86359530 Common cycY thiol disulfide interchange protein (involved in cytochrome-c biogenesis) RHE_CH03950 140 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 86359649 Common modA molybdenum ABC transporter, substrate-binding protein RHE_CH04071 147 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 86356086 Common sigK RNA polymerase sigma factor RHE_CH00429 88 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 86356417 Common nlpE1 lipopolysaccharide biosynthesis protein (SAM-dependent methyltransferase protein) RHE_CH00768 71 COG4798 COG4798, Predicted methyltransferase General function prediction only 86358353 Common - putative hydrolase protein RHE_CH02748 115 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 86356339 Common - hypothetical protein RHE_CH00688 3 None None None 86357583 Common - 2-octaprenyl-6-methoxyphenyl hydroxylase RHE_CH01962 125 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 86357879 Common - probable metalloendopeptidase protein RHE_CH02264 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 86358250 Common - hypothetical protein RHE_CH02644 3 None None None 86357217 Nonpathogen - hypothetical protein RHE_CH01580 1 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 86357863 Common - hypothetical protein RHE_CH02248 132 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 86358239 Nonpathogen - hypothetical protein RHE_CH02632 1 None None None 86359565 Common - probable sulfatase (sulfuric ester hydrolase) protein RHE_CH03986 87 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 86357232 Nonpathogen - hypothetical protein RHE_CH01595 5 None None None 86357927 Common rpsD 30S ribosomal protein S4 RHE_CH02312 222 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 86357001 Common - probable acetyltransferase protein RHE_CH01363 100 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 86359318 Common - putative Ca2+/H+ antiporter protein RHE_CH03728 57 COG0387 ChaA, Ca2+/H+ antiporter Inorganic ion transport and metabolism 86358977 Common - probable sugar ABC transporter, ATP-binding protein RHE_CH03379 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 86358635 Common - probable enoyl-CoA hydratase protein RHE_CH03033 66 COG2030 MaoC, Acyl dehydratase Lipid metabolism 86359508 Common - putative sugar ABC transporter, permease protein RHE_CH03928 57 COG4120 COG4120, ABC-type uncharacterized transport system, permease component General function prediction only 86357458 Common - hypothetical protein RHE_CH01830 89 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 86357451 Common tatA twin argininte translocase protein A RHE_CH01823 31 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 86356478 Common ileS isoleucyl-tRNA synthetase RHE_CH00832 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 86358481 Common ilvG acetolactate synthase 2 catalytic subunit RHE_CH02878 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 86359642 Common - putative acetyltransferase protein RHE_CH04064 96 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 86357610 Common - hypothetical protein RHE_CH01990 16 None None None 86358234 Common - putative transcriptional regulator protein RHE_CH02627 42 COG1396 HipB, Predicted transcriptional regulators Transcription 86356568 Common matC dicarboxylate-carrier protein RHE_CH00922 15 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 86357152 Common rffB dTDP-glucose-4,6-dehydratase protein RHE_CH01514 232 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 86357316 Common rplX 50S ribosomal protein L24 RHE_CH01686 213 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 86355894 Common - probable recombinase, resolvase family RHE_CH00235 138 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 86356161 Common - hypothetical protein RHE_CH00507 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 86357003 Common - putative aminotransferase protein RHE_CH01365 193 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 86357760 Common occQch octopine ABC transporter, permease protein RHE_CH02141 171 COG4215 ArtQ, ABC-type arginine transport system, permease component Amino acid transport and metabolism 86355961 Common - hypothetical protein RHE_CH00304 35 COG3487 IrpA, Uncharacterized iron-regulated protein Inorganic ion transport and metabolism 86355726 Common ocdch1 ornithine cyclodeaminase RHE_CH00058 86 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 86358665 Common - putative phosphatase protein RHE_CH03063 35 COG1409 Icc, Predicted phosphohydrolases General function prediction only 86356408 Nonpathogen - hypothetical protein RHE_CH00759 3 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 86358585 Common - probable sugar ABC transporter, permease protein RHE_CH02983 180 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 86358312 Common - hypothetical protein RHE_CH02706 13 COG5485 COG5485, Predicted ester cyclase General function prediction only 86358004 Common - probable transcriptional regulator protein, MarR family RHE_CH02389 74 COG1846 MarR, Transcriptional regulators Transcription 86358257 Nonpathogen - hypothetical protein RHE_CH02651 3 None None None 86356230 Common - hypothetical protein RHE_CH00578 3 None None None 86358496 Common - probable ABC transporter, ATP-binding protein RHE_CH02893 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 86358970 Common ugpBch2 sn-glycerol 3-phosphate ABC transporter, substrate-binding protein RHE_CH03372 86 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86358196 Common - hypothetical protein RHE_CH02589 22 COG3698 COG3698, Predicted periplasmic protein Function unknown 86358432 Common senC cytochrome-c oxidase assembly factor protein RHE_CH02829 105 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 86357110 Common ndk nucleoside diphosphate kinase RHE_CH01472 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 86357220 Common - hypothetical protein RHE_CH01583 33 COG3450 COG3450, Predicted enzyme of the cupin superfamily General function prediction only 86357653 Common - hypothetical protein RHE_CH02034 120 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 86358897 Common - putative protein secretion protein, HlyD family RHE_CH03298 168 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 86357419 Common rbsCch2 ribose ABC transporter, permease protein RHE_CH01789 97 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 86357497 Common aroQ1 3-dehydroquinate dehydratase RHE_CH01871 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 86359404 Common cobS cobalamin biosynthesis protein RHE_CH03821 68 COG0714 COG0714, MoxR-like ATPases General function prediction only 86359638 Common - hypothetical protein RHE_CH04059 22 COG5368 COG5368, Uncharacterized protein conserved in bacteria Function unknown 86357964 Common - probable ABC transporter, permease protein RHE_CH02349 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 86355735 Common - probable transcriptional regulator protein, LacI family RHE_CH00074 124 COG1609 PurR, Transcriptional regulators Transcription 86358593 Common - hypothetical protein RHE_CH02991 36 COG2320 GrpB, Uncharacterized conserved protein Function unknown 86357509 Common - hypothetical protein RHE_CH01886 90 COG1430 COG1430, Uncharacterized conserved protein Function unknown 86358027 Common - probable epoxide hydrolase protein RHE_CH02414 57 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 86358348 Common - hypothetical protein RHE_CH02743 15 None None None 86359117 Common - hypothetical protein RHE_CH03526 105 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 86357183 Common - hypothetical protein RHE_CH01545 5 None None None 86358641 Common - putative endonuclease/exonuclease/phosphatase family protein RHE_CH03039 7 COG3021 COG3021, Uncharacterized protein conserved in bacteria Function unknown 86356332 Common flgL flagellar hook-associated protein FlgL RHE_CH00681 32 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 86356651 Nonpathogen - hypothetical protein RHE_CH01005 1 None None None 86358200 Common dapB2 dihydrodipicolinate reductase protein RHE_CH02593 211 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 86358172 Common uvrB excinuclease ABC subunit B RHE_CH02563 227 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 86358756 Common - hypothetical conserved membrane protein RHE_CH03155 46 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 86356490 Common kdtA 3-deoxy-D-manno-octulosonic-acid transferase RHE_CH00844 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 86359409 Common aroK shikimate kinase protein RHE_CH03826 202 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 86358458 Common mraW S-adenosyl-methyltransferase MraW RHE_CH02855 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 86355937 Common - putative transporter, permease protein (related to regulator protein pecM) RHE_CH00279 155 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 86357430 Nonpathogen - hypothetical protein RHE_CH01800 1 None None None 86358719 Nonpathogen - hypothetical protein RHE_CH03118 1 None None None 86356150 Common - probable L-fucose dehydrogenase protein RHE_CH00494 168 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 86355839 Common - probable hydroxyacid dehydrogenase protein RHE_CH00179 225 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 86358284 Common - putative transcriptional regulator protein, ArsR family RHE_CH02678 8 COG4189 COG4189, Predicted transcriptional regulator Transcription 86357494 Common aat leucyl/phenylalanyl-tRNA--protein transferase RHE_CH01868 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 86358148 Common - hypothetical protein RHE_CH02538 63 COG3803 COG3803, Uncharacterized protein conserved in bacteria Function unknown 86359603 Common fdxA ferredoxin III protein RHE_CH04024 155 COG1146 COG1146, Ferredoxin Energy production and conversion 86358386 Common nthB nitrile hydratase beta subunit protein RHE_CH02782 18 None None None 86357159 Common - putative glucosyltransferase protein RHE_CH01521 71 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 86357719 Common - putative signal peptide protein RHE_CH02100 15 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 86356785 Common - putative transporter, permease protein RHE_CH01143 24 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86357387 Nonpathogen - hypothetical protein RHE_CH01757 2 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 86358568 Common carB carbamoyl phosphate synthase large subunit RHE_CH02966 233 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 86359297 Common - probable sugar ABC transporter, permease protein RHE_CH03707 161 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 86357897 Common - hypothetical protein RHE_CH02282 6 None None None 86355862 Common cpaA prepilin peptidase protein RHE_CH00203 16 COG4960 CpaA, Flp pilus assembly protein, protease CpaA Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 86356619 Common - hypothetical protein RHE_CH00973 14 None None None 86357423 Common - hypothetical protein RHE_CH01793 97 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 86356278 Nonpathogen - putative two-component response regulator protein RHE_CH00627 2 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 86357768 Common aacC2 aminoglycoside N6`-acetyltransferase protein RHE_CH02150 19 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 86356116 Common - probable zinc-binding oxidoreductase protein RHE_CH00460 195 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 86356528 Nonpathogen - hypothetical protein RHE_CH00882 4 COG1936 COG1936, Predicted nucleotide kinase (related to CMP and AMP kinases) Nucleotide transport and metabolism 86356838 Common - probable multi-drug resistance efflux system protein RHE_CH01198 200 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86357663 Common - probable nitrate/sulfonate/bicarbonate ABC transporter, permease protein RHE_CH02044 146 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 86358611 Common - probable two-component sensor histidine kinase protein RHE_CH03009 211 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 86358778 Nonpathogen - hypothetical protein RHE_CH03178 1 None None None 86356144 Common cutC copper homeostasis protein RHE_CH00488 56 COG3142 CutC, Uncharacterized protein involved in copper resistance Inorganic ion transport and metabolism 86356736 Common - putative terminase large subunit protein RHE_CH01093 23 None None None 86357678 Common - probable transcriptional regulator protein, GntR family RHE_CH02059 130 COG2186 FadR, Transcriptional regulators Transcription 86356588 Common - hypothetical protein RHE_CH00942 26 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 86355869 Common - probable pilus assembly protein RHE_CH00210 75 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 86355685 Common - probable intracellular PHB depolymerase protein RHE_CH00017 44 COG4553 DepA, Poly-beta-hydroxyalkanoate depolymerase Lipid metabolism 86357952 Common - hypothetical protein RHE_CH02337 9 COG5661 COG5661, Predicted secreted Zn-dependent protease Posttranslational modification, protein turnover, chaperones 86359143 Common - hypothetical protein RHE_CH03552 37 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 86356083 Common - probable fatty acid desaturase protein RHE_CH00426 53 COG1398 OLE1, Fatty-acid desaturase Lipid metabolism 86355774 Common truB tRNA pseudouridine synthase B RHE_CH00114 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 86355916 Common - hypothetical protein RHE_CH00258 24 COG3672 COG3672, Predicted periplasmic protein Function unknown 86359279 Common - putative transcriptional regulator protein, TetR family RHE_CH03689 52 COG1309 AcrR, Transcriptional regulator Transcription 86357571 Common - probable voltage-gated potassium channel beta subunit protein RHE_CH01950 197 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 86357239 Common - hypothetical protein RHE_CH01605 15 None None None 86358333 Common mocA oxidoreductase protein RHE_CH02728 198 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 86358771 Common idhA myo-inositol 2-dehydrogenase protein RHE_CH03170 183 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 86355789 Common - probable transcriptional regulator protein RHE_CH00129 85 COG2378 COG2378, Predicted transcriptional regulator Transcription 86356717 Common gstch5 glutathione S-transferase protein RHE_CH01074 64 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 86357441 Nonpathogen - hypothetical protein RHE_CH01813 1 None None None 86356746 Nonpathogen - hypothetical protein RHE_CH01104 1 None None None 86358580 Common - probable MFS transporter protein RHE_CH02978 169 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86358122 Nonpathogen - hypothetical protein RHE_CH02510 1 None None None 86358506 Common - hypothetical protein RHE_CH02903 20 COG4702 COG4702, Uncharacterized conserved protein Function unknown 86356599 Common ctaD cytochrome-c oxidase, subunit I protein RHE_CH00953 171 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 86359687 Common - probable RNA methyltransferase - sun protein RHE_CH04109 206 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 162329628 Common amaB allantoate amidohydrolase RHE_CH03290 84 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 86355704 Common chvI two-component response regulator protein RHE_CH00036 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 86357733 Common ppiA peptidyl prolyl cis-trans isomerase A signal peptide protein RHE_CH02114 197 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 86359628 Common - hypothetical protein RHE_CH04049 22 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 86358055 Common cobT nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase RHE_CH02443 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 86356441 Nonpathogen - hypothetical protein RHE_CH00795 1 None None None 86355926 Common - hypothetical protein RHE_CH00268 36 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 86358978 Common exsH endo-1,3-1,4-beta-glycanase protein RHE_CH03380 42 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 86359553 Common amtB ammonium transporter protein RHE_CH03973 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 86359386 Common ftsX cell division protein RHE_CH03803 35 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 86357572 Common ntrY nitrogen regulation (two-component sensor histidine kinase) protein RHE_CH01951 220 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 86357592 Nonpathogen - hypothetical protein RHE_CH01972 1 None None None 86356225 Common - putative beta-lactamase family protein RHE_CH00572 80 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 86358115 Common - hypothetical protein RHE_CH02503 14 COG3798 COG3798, Uncharacterized protein conserved in bacteria Function unknown 86355790 Common - putative glyoxalase protein RHE_CH00130 22 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 86355901 Common - hypothetical protein RHE_CH00243 4 None None None 86356880 Common - hypothetical protein RHE_CH01240 8 None None None 86358468 Common - putative 6-aminohexanoate-dimer hydrolase protein RHE_CH02865 73 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 86359493 Common - hypothetical protein RHE_CH03912 15 COG1872 COG1872, Uncharacterized conserved protein Function unknown 86358453 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase RHE_CH02850 212 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 86356176 Common metZ O-succinylhomoserine sulfhydrylase RHE_CH00522 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 86359202 Common pntA1 NAD(P)(+) transhydrogenase (AB-specific), alpha subunit protein RHE_CH03612 117 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 86359171 Common - hypothetical protein RHE_CH03581 40 COG2899 COG2899, Uncharacterized protein conserved in bacteria Function unknown 86356818 Common - putative glyoxalase protein RHE_CH01178 44 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 86356342 Common - hypothetical protein RHE_CH00691 11 None None None 86359658 Common ialA dinucleoside polyphosphate hydrolase RHE_CH04080 114 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 86358556 Common dnaG DNA primase RHE_CH02954 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 86357201 Common - hypothetical protein RHE_CH01564 11 None None None 86357938 Common recA recombinase A RHE_CH02323 214 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 86358152 Common - putative NTP pyrophosphohydrolase protein, MutT/nudix family RHE_CH02542 8 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 86357966 Common - putative 3-phenylpropionic acid permease protein RHE_CH02351 69 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86356996 Common - putative teichoic acid biosynthesis, UDP-N-acetyl-D-mannosaminuronic acid transferase protein RHE_CH01358 110 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 86358985 Nonpathogen - probable glycosyltransferase protein RHE_CH03387 7 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 86356951 Common - probable transcriptional regulator protein, AsnC family RHE_CH01311 159 COG1522 Lrp, Transcriptional regulators Transcription 86356744 Common - hypothetical protein RHE_CH01102 4 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 162329648 Common hisA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase RHE_CH00043 215 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 86356074 Common dapE2 succinyl-diaminopimelate desuccinylase RHE_CH00417 208 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 86359700 Common gidA2 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA RHE_CH04122 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 86355953 Nonpathogen - hypothetical protein RHE_CH00296 2 None None None 86358928 Common - hypothetical protein RHE_CH03330 27 None None None 86358378 Common - hypothetical protein RHE_CH02774 37 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 86359695 Common - hypothetical protein RHE_CH04117 15 COG5468 COG5468, Predicted secreted (periplasmic) protein Function unknown 86357284 Common - hypothetical protein RHE_CH01650 3 None None None 86357822 Common - hypothetical protein RHE_CH02206 18 COG5388 COG5388, Uncharacterized protein conserved in bacteria Function unknown 86359262 Common - probable transcriptional regulator protein, TetR family RHE_CH03672 27 COG1309 AcrR, Transcriptional regulator Transcription 86355879 Common - probable dipeptide ABC transporter, permease protein RHE_CH00220 220 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 86358561 Common - probable adenylate cyclase protein RHE_CH02959 108 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 86356890 Common - hypothetical protein RHE_CH01250 96 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 86357420 Common rbsCch3 ribose ABC transporter, permease protein RHE_CH01790 114 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 86356674 Common - hypothetical protein RHE_CH01030 2 None None None 86355718 Common - hypothetical protein RHE_CH00050 6 None None None 86359125 Common - hypothetical protein RHE_CH03534 37 None None None 86356203 Common - putative phosphoesterase protein RHE_CH00550 56 COG1407 COG1407, Predicted ICC-like phosphoesterases General function prediction only 86356795 Common - probable transcriptional regulator protein, LysR family RHE_CH01154 121 COG0583 LysR, Transcriptional regulator Transcription 86359355 Common - putative polysaccharide biosynthesis associated protein RHE_CH03771 21 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 86358271 Common - putative transporter, permease protein RHE_CH02665 42 None None None 86359060 Nonpathogen sqdD glycosyltransferase (sulfolipid biosynthesis) protein RHE_CH03469 5 COG5597 COG5597, Alpha-N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 86356669 Common - probable phosphoglycerate dehydrogenase protein RHE_CH01024 214 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 86358971 Common - probable transcriptional regulator protein, ROK family RHE_CH03373 153 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 86359079 Common - 6-phosphogluconate dehydrogenase-like protein RHE_CH03488 162 COG1023 Gnd, Predicted 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 86356660 Common - hypothetical protein RHE_CH01015 4 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 86356349 Common aglG alpha-glucoside ABC transporter, permease protein RHE_CH00698 146 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 86357705 Common - probable sugar ABC transporter, ATP-binding protein RHE_CH02086 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 86358886 Nonpathogen - hypothetical protein RHE_CH03287 1 None None None 86357529 Common - putative hydrolase protein, HIT family RHE_CH01908 231 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 86358043 Common - hypothetical protein RHE_CH02430 14 COG3832 COG3832, Uncharacterized conserved protein Function unknown 86359269 Common smoK sorbitol/mannitol ABC transporter, ATP-binding protein RHE_CH03679 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 86358422 Common uvrD2 DNA helicase II protein RHE_CH02819 231 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 86356378 Common - hypothetical protein RHE_CH00728 4 None None None 86358763 Common gguC GguC protein RHE_CH03162 14 COG3802 GguC, Uncharacterized protein conserved in bacteria Function unknown 86357771 Nonpathogen - hypothetical protein RHE_CH02153 4 None None None 86357812 Common thrS threonyl-tRNA synthetase RHE_CH02196 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 86356936 Common glnE glutamate-ammonia-ligase adenylyltransferase protein RHE_CH01296 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 86357090 Common - putative organic solvent tolerance protein OstA RHE_CH01452 119 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 86356066 Common rbsK ribose kinase protein RHE_CH00409 144 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 86357478 Common - hypothetical protein RHE_CH01851 3 None None None 86355758 Common rpsA 30S ribosomal protein S1 RHE_CH00097 219 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 86359676 Common - hypothetical protein RHE_CH04098 5 None None None 86358806 Nonpathogen - hypothetical protein RHE_CH03206 2 None None None 86359067 Common - probable oxidoreductase protein RHE_CH03476 115 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 86357262 Common - hypothetical protein RHE_CH01628 28 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 86357507 Common gloA lactoylglutathione lyase methylglyoxalase protein RHE_CH01884 125 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 86358602 Common - hypothetical protein RHE_CH03000 49 COG2425 COG2425, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 86357789 Common - hypothetical protein RHE_CH02172 5 None None None 86357795 Common - putative SAM-dependent methyltransferease protein RHE_CH02178 23 COG3897 COG3897, Predicted methyltransferase General function prediction only 86358483 Common - hypothetical protein RHE_CH02880 43 COG3453 COG3453, Uncharacterized protein conserved in bacteria Function unknown 86357545 Common - hypothetical protein RHE_CH01924 45 COG3494 COG3494, Uncharacterized protein conserved in bacteria Function unknown 86357635 Common - putative insertion sequence transposase protein RHE_CH02015 52 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 86358571 Common greA transcription elongation factor GreA RHE_CH02969 204 COG0782 GreA, Transcription elongation factor Transcription 86356773 Common cysD sulfate adenylyltransferase subunit 2 RHE_CH01131 127 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 86356105 Common - probable oxidoreductase protein RHE_CH00449 202 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 86355908 Common - probable transcriptional regulator protein, LacI family RHE_CH00250 90 COG1396 HipB, Predicted transcriptional regulators Transcription 86357104 Common - probable transcriptional regulator protein, TetR family RHE_CH01466 57 COG1309 AcrR, Transcriptional regulator Transcription 86356966 Nonpathogen - hypothetical protein RHE_CH01326 1 None None None 86356466 Common - hypothetical protein RHE_CH00820 6 None None None 86355763 Common - hypothetical protein RHE_CH00103 60 COG1434 COG1434, Uncharacterized conserved protein Function unknown 86358626 Nonpathogen - hypothetical protein RHE_CH03024 3 None None None 86356265 Common rbsCch1 ribose ABC transporter, permease protein RHE_CH00614 163 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 86357655 Common - hypothetical protein RHE_CH02036 13 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 86358305 Common - putative mRNA-binding protein RHE_CH02699 32 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 86357852 Common - probable integral membrane protein (possibly involved in chromosome condensation), CrcB family RHE_CH02237 129 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 86356008 Common - probable allantoinase protein RHE_CH00351 202 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 86356293 Common cheBch1 chemotaxis-specific methylesterase RHE_CH00642 213 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 86358540 Common - hypothetical protein RHE_CH02938 130 COG0432 COG0432, Uncharacterized conserved protein Function unknown 86356963 Common - hypothetical protein RHE_CH01323 43 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 86356652 Common - hypothetical protein RHE_CH01006 3 None None None 86358286 Common - probable ferrichrome ABC transporter, ATP-binding protein RHE_CH02680 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 86358246 Common - probable desaturase protein RHE_CH02640 23 COG3000 ERG3, Sterol desaturase Lipid metabolism 86356887 Common msrB methionine sulfoxide reductase B RHE_CH01247 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 86357815 Common - hypothetical protein RHE_CH02199 179 COG0759 COG0759, Uncharacterized conserved protein Function unknown 86356137 Common lguL lactoylglutathione lyase protein RHE_CH00481 119 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 86357522 Common - hypothetical protein RHE_CH01901 14 COG4391 COG4391, Uncharacterized protein conserved in bacteria Function unknown 86359522 Common - hypothetical protein RHE_CH03942 30 None None None 86358992 Common - putative pyrroloquinoline-quinone-dependent quinate dehydrogenase protein RHE_CH03394 58 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 86357643 Nonpathogen - hypothetical protein RHE_CH02024 4 None None None 86357666 Common - probable transcriptional regulator protein, LysR family RHE_CH02047 191 COG0583 LysR, Transcriptional regulator Transcription 86355677 Common - putative translocase transmembrane protein RHE_CH00008 40 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 86359445 Common - putative nitrate/sulfonate/bicarbonate ABC transporter, permease protein RHE_CH03864 127 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 86355856 Common add adenosine deaminase RHE_CH00197 107 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 86356750 Nonpathogen - hypothetical protein RHE_CH01108 1 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 86358549 Common - putative aminoglycoside 3`-phosphotransferase protein RHE_CH02947 20 COG3231 Aph, Aminoglycoside phosphotransferase Translation, ribosomal structure and biogenesis 86358963 Common - probable short-chain alcohol dehydrogenase protein RHE_CH03365 236 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 86357804 Common parE DNA topoisomerase IV subunit B RHE_CH02188 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 86356732 Common - putative hydrolase protein RHE_CH01089 32 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 86356634 Common - probable transcriptional regulator protein, LysR family RHE_CH00988 93 COG0583 LysR, Transcriptional regulator Transcription 86357924 Common - putative inositol monophosphatase protein RHE_CH02309 197 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 86359415 Common dacF2 D-alanyl-D-alanine carboxypeptidase protein RHE_CH03832 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 86358404 Common - hypothetical protein RHE_CH02800 40 COG3814 COG3814, Uncharacterized protein conserved in bacteria Function unknown 86359276 Common hexA beta-N-acetylhexosaminidase protein RHE_CH03686 56 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 86356160 Common - putative regulator protein RHE_CH00506 6 None None None 86356318 Common fliP flagellar biosynthesis protein FliP RHE_CH00667 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 86358022 Common mobB molybdopterin-guanine dinucleotide biosynthesis protein RHE_CH02407 105 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 86359375 Common etfBch electron transport flavoprotein, beta subunit RHE_CH03792 152 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 86357086 Common gmk guanylate kinase RHE_CH01448 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 86359084 Common - hypothetical protein RHE_CH03493 32 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 86356839 Common - hypothetical protein RHE_CH01199 5 None None None 86357071 Common - probable transcriptional regulator protein, AraC family RHE_CH01433 95 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 86355877 Common gatA1 amidase RHE_CH00218 217 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 86359285 Common - putative sugar ABC transporter, substrate-binding protein RHE_CH03695 45 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86358913 Common - probable urea or short-chain amide ABC transporter, ATP-binding protein RHE_CH03314 249 COG4674 COG4674, Uncharacterized ABC-type transport system, ATPase component General function prediction only 86357375 Common - probable 4-hydroxyphenylpyruvate dioxygenase protein RHE_CH01745 78 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 86359048 Common - probable phosphosugar isomerase protein RHE_CH03457 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 86356587 Common pdxH pyridoxamine 5'-phosphate oxidase RHE_CH00941 133 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 86359624 Common - hypothetical protein RHE_CH04045 17 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 86356327 Common motD chemotaxis motility protein RHE_CH00676 6 None None None 86357165 Common hppA membrane-bound proton-translocating pyrophosphatase RHE_CH01527 100 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 162329627 Common xerD site-specific tyrosine recombinase XerD RHE_CH03827 226 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 86358434 Common cheW2 chemotaxis signal transduction protein RHE_CH02831 139 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 86355938 Common - probable aminopeptidase protein RHE_CH00280 56 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 86358895 Common - probable nitrate/sulfonate ABC transporter, permease protein RHE_CH03296 160 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 86359428 Common hemAch 5-aminolevulinate synthase RHE_CH03846 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 86357974 Common - probable sugar ABC transporter, ATP-binding protein RHE_CH02359 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 86358026 Common - probable two-component response regulator protein RHE_CH02413 215 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 86358619 Common - hypothetical protein RHE_CH03017 28 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 86356117 Common - putative transcriptional regulator protein, TetR family RHE_CH00461 91 COG1309 AcrR, Transcriptional regulator Transcription 86356627 Common - probable cytochrome-c protein RHE_CH00981 59 COG2863 COG2863, Cytochrome c553 Energy production and conversion 86356515 Common - hypothetical protein RHE_CH00869 107 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 86358705 Common glnII glutamine synthetase II protein RHE_CH03104 92 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 86356764 Common - probable transcriptional regulator protein, LysR family RHE_CH01122 118 COG0583 LysR, Transcriptional regulator Transcription 86359517 Common tesA acyl-CoA thioesterase protein RHE_CH03937 101 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 86358124 Common - hypothetical protein RHE_CH02512 42 None None None 86356031 Common - hypothetical protein RHE_CH00374 176 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 86358708 Common - probable transcriptional regulator protein, MarR family RHE_CH03107 106 COG1846 MarR, Transcriptional regulators Transcription 86356394 Common - hypothetical protein RHE_CH00745 19 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 86356809 Common cspA2 cold shock protein RHE_CH01169 174 COG1278 CspC, Cold shock proteins Transcription 86356470 Common - hypothetical conserved membrane protein RHE_CH00824 35 COG2259 COG2259, Predicted membrane protein Function unknown 86358863 Common - hypothetical protein RHE_CH03264 11 None None None 86356112 Common - probable two-component response regulator protein RHE_CH00456 31 COG5616 COG5616, Predicted integral membrane protein Function unknown 86356620 Common mcpX2 methyl-accepting chemotaxis protein RHE_CH00974 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 86359567 Common mocBch2 rhizopine ABC transporter, substrate-binding protein RHE_CH03988 109 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86359368 Common alkA DNA-3-methyladenine glycosidase II protein RHE_CH03785 110 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 86356258 Common appC oligopeptide ABC transporter, permease protein RHE_CH00607 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 86355845 Common - hypothetical protein RHE_CH00186 4 None None None 86358827 Common prsE protein secretion protein, HlyD family RHE_CH03228 117 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 86358072 Common - probable sugar ABC transporter, permease protein RHE_CH02460 152 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 86357902 Common - probable stress-induced morphogen protein, BolA family RHE_CH02287 78 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 86358642 Common - probable ABC transporter, ATP-binding protein RHE_CH03040 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 86358675 Common - hypothetical protein RHE_CH03073 14 COG5482 COG5482, Uncharacterized conserved protein Function unknown 86358524 Common - hypothetical protein RHE_CH02922 2 None None None 86358116 Nonpathogen - hypothetical protein RHE_CH02504 3 None None None 86357121 Common - putative DNA methylase protein RHE_CH01483 85 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 86357886 Nonpathogen - hypothetical protein RHE_CH02271 3 COG5497 COG5497, Predicted secreted protein Function unknown 86358207 Nonpathogen - hypothetical protein RHE_CH02600 1 None None None 86356846 Common - putative amino acid efflux protein, LysE family RHE_CH01206 120 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 86357134 Common - probable metallo-oxidoreductase protein RHE_CH01496 126 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 86357516 Common aapP general L-amino acid ABC transporter, ATP-binding protein RHE_CH01895 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 86357113 Common - probable branched-chain amino acid ABC transporter, permease protein RHE_CH01475 71 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 86356303 Common fliN flagellar motor switch protein RHE_CH00652 120 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 86358883 Common - putative rhodanese-related sulfurtransferase protein RHE_CH03284 24 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 86357019 Common dapAch2 dihydrodipicolinate synthase RHE_CH01381 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 86359484 Common gcp O-sialoglycoprotein endopeptidase RHE_CH03903 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 86358294 Common ribH2 riboflavin synthase subunit beta RHE_CH02688 155 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 86357559 Common lpdAch1 dihydrolipoamide dehydrogenase RHE_CH01938 245 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 86357839 Common - probable permease protein RHE_CH02224 102 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 86359521 Common - putative phosphinothricin N-acetyltransferase (antibiotic resistance) protein RHE_CH03941 124 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 86359212 Common - probable transcriptional regulator protein, LacI family RHE_CH03622 127 COG1609 PurR, Transcriptional regulators Transcription 86357124 Common phnM2 phosphonate metabolism protein RHE_CH01486 53 COG3454 COG3454, Metal-dependent hydrolase involved in phosphonate metabolism Inorganic ion transport and metabolism 86358592 Common - probable transcriptional regulator protein, LysR family RHE_CH02990 176 COG0583 LysR, Transcriptional regulator Transcription 86355797 Nonpathogen - hypothetical protein RHE_CH00137 1 None None None 86358213 Common plyA2 polysaccharidase protein RHE_CH02606 20 None None None 86357227 Common hrm bacterial nucleoid DNA-binding protein RHE_CH01590 199 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 86359618 Common - hypothetical protein RHE_CH04039 9 None None None 86356437 Common - putative lactoylglutathione lyase protein RHE_CH00791 52 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 86357249 Common nuoK1 NADH dehydrogenase subunit K RHE_CH01615 136 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 86357406 Common chrR transcriptional activator (anti-sigma factor) protein RHE_CH01776 30 COG3806 ChrR, Transcriptional activator Transcription 86357658 Common - probable transcriptional regulator protein, AraC family RHE_CH02039 154 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 86356943 Common - probable molecular chaperone heat shock protein, Hsp70 family RHE_CH01303 226 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 86359049 Common ftsH cell division metalloproteinase protein RHE_CH03458 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 86359040 Common - probable branched-chain amino acid ABC transporter, ATP-binding protein RHE_CH03448 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 86359392 Common tyrC cyclohexadienyl dehydrogenase RHE_CH03809 174 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 86356211 Common fadA acetyl-CoA acetyltransferase RHE_CH00558 171 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 86356864 Common - probable efflux-type transporter, drug resistance translocase protein RHE_CH01224 197 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86357394 Common acpD [acyl-carrier-protein] phosphodiesterase protein RHE_CH01764 98 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 86357363 Nonpathogen - hypothetical protein RHE_CH01733 3 COG4278 COG4278, Uncharacterized conserved protein Function unknown 86356901 Common pbp cell wall biosynthesis penicillin-binding protein, 1A family RHE_CH01261 202 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 86358133 Nonpathogen - hypothetical protein RHE_CH02523 1 None None None 86358479 Common - putative transporter, permease protein RHE_CH02876 94 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 86358893 Common - probable nitrate/sulfonate ABC transporter, ATP-binding protein RHE_CH03294 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 86357454 Common serS seryl-tRNA synthetase RHE_CH01826 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 86355957 Common - hypothetical protein RHE_CH00300 24 COG4320 COG4320, Uncharacterized protein conserved in bacteria Function unknown 86357412 Common nirB nitrite reductase [NAD(P)H], large subunit protein RHE_CH01782 203 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 86357618 Common - hypothetical protein RHE_CH01998 19 None None None 86359363 Common - probable cation transporter protein RHE_CH03780 196 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 86358220 Common - hypothetical conserved membrane protein RHE_CH02613 9 COG5605 COG5605, Predicted small integral membrane protein Function unknown 86357599 Common argD2 diaminobutyrate--pyruvate aminotransferase protein RHE_CH01979 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 86358448 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase RHE_CH02845 147 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 86356774 Common cysH phosphoadenosine-phosphosulfate reductase protein RHE_CH01132 152 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 86355744 Common - probable sugar ABC transporter, permease protein RHE_CH00083 146 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 86356479 Common - hypothetical protein RHE_CH00833 7 None None None 86359450 Common atpC F0F1 ATP synthase subunit epsilon RHE_CH03869 152 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 86358743 Common - putative chitooligosaccharide deacetylase protein RHE_CH03142 59 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 86356748 Nonpathogen - hypothetical protein RHE_CH01106 2 None None None 86359333 Common - hypothetical protein RHE_CH03743 54 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 86355944 Common - probable methylated-DNA-[protein]-cysteine S-methyltransferase protein RHE_CH00287 213 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 86357136 Common - hypothetical protein RHE_CH01498 6 None None None 86357351 Common - probable enoyl-CoA hydratase protein RHE_CH01721 154 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 86358308 Common - probable acetyltransferase protein RHE_CH02702 210 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 86357896 Common purQ phosphoribosylformylglycinamidine synthase subunit I RHE_CH02281 231 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 86356853 Common - probable transcriptional regulator protein, LacI family RHE_CH01213 34 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86355997 Common - probable transcriptional regulator protein, GntR family RHE_CH00340 144 COG2186 FadR, Transcriptional regulators Transcription 86357358 Common - probable FAD-dependent L-sorbose dehydrogenase protein RHE_CH01728 88 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 86357724 Common - hypothetical protein RHE_CH02105 78 COG1801 COG1801, Uncharacterized conserved protein Function unknown 86357036 Common - putative signal-transducer protein RHE_CH01398 177 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 86358334 Common - probable aminotransferase protein RHE_CH02729 222 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 86358005 Common - hypothetical conserved membrane protein RHE_CH02390 25 COG4292 COG4292, Predicted membrane protein Function unknown 86356097 Common mcpT methyl-accepting chemotaxis protein RHE_CH00440 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 86359346 Common grxC glutaredoxin protein RHE_CH03762 117 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 86356832 Common - probable multidrug resistance efflux system protein RHE_CH01192 164 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 86356412 Common nolK GDP-L-fucose synthase protein RHE_CH00763 219 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 86357347 Common - putative two-component sensor histidine kinase protein RHE_CH01717 71 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 86356914 Nonpathogen - hypothetical protein RHE_CH01274 1 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 86356338 Common fliR flagellar biosynthesis protein FliR RHE_CH00687 119 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 86358758 Common - hypothetical protein RHE_CH03157 82 COG2307 COG2307, Uncharacterized protein conserved in bacteria Function unknown 86358314 Nonpathogen - hypothetical protein RHE_CH02708 1 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 86355777 Common - hypothetical protein RHE_CH00117 36 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 86357385 Common - putative universal stress protein RHE_CH01755 38 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 86356110 Common - hypothetical protein RHE_CH00454 7 None None None 86359685 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase RHE_CH04107 218 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 86359569 Common - probable sugar ABC transporter, permease protein RHE_CH03990 126 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 86359408 Common aroB 3-dehydroquinate synthase RHE_CH03825 209 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 86357762 Common speB2 agmatinase protein RHE_CH02143 153 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 86358276 Common - hypothetical protein RHE_CH02670 22 COG3823 COG3823, Glutamine cyclotransferase Posttranslational modification, protein turnover, chaperones 86359004 Common - probable multidrug efflux transporter protein RHE_CH03412 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 86357751 Common - hypothetical protein RHE_CH02132 5 None None None 86355936 Common - probable transcriptional regulator protein, MarR family RHE_CH00278 116 COG1846 MarR, Transcriptional regulators Transcription 86357807 Common - hypothetical protein RHE_CH02191 3 None None None 86358149 Common - putative two-component sensor histidine kinase/response regulator hybrid protein RHE_CH02539 101 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 86357468 Common - hypothetical conserved membrane protein RHE_CH01840 15 COG4929 COG4929, Uncharacterized membrane-anchored protein Function unknown 86357999 Common rapB2 autoaggregation protein (adhering protein) RHE_CH02384 14 None None None 86356869 Common - putative oxidoreductase protein RHE_CH01229 114 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 86356522 Common - hypothetical protein RHE_CH00876 23 None None None 86357338 Common - recombination factor protein RarA RHE_CH01708 219 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 86356121 Common frcB fructose ABC transporter, substrate-binding protein RHE_CH00465 94 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86356271 Common - putative membrane-anchored protein (osmotically inducible protein) RHE_CH00620 6 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 86357866 Common sufC ABC transporter involved in Fe-S cluster assembly, ATP-binding protein RHE_CH02251 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 162329631 Common bacA transport protein RHE_CH03112 58 COG1133 SbmA, ABC-type long-chain fatty acid transport system, fused permease and ATPase components Lipid metabolism 86357040 Common - putative tyrosine phosphatase protein RHE_CH01402 14 COG5350 COG5350, Predicted protein tyrosine phosphatase General function prediction only 86358536 Nonpathogen - hypothetical protein RHE_CH02934 1 None None None 86359145 Common omp3 outer membrane lipoprotein RHE_CH03554 7 None None None 86358866 Common hmuP hemin transport system, hemin uptake protein RHE_CH03267 6 COG4256 HemP, Hemin uptake protein Inorganic ion transport and metabolism 86358857 Common - probable transcriptional regulator protein, TetR family RHE_CH03258 36 COG1309 AcrR, Transcriptional regulator Transcription 86357465 Common - hypothetical protein RHE_CH01837 5 COG5457 COG5457, Uncharacterized conserved small protein Function unknown 86357012 Common - hypothetical protein RHE_CH01374 88 None None None 86357324 Common rplO 50S ribosomal protein L15 RHE_CH01694 216 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 86355863 Common cpaB pilus assembly protein RHE_CH00204 60 COG3745 CpaB, Flp pilus assembly protein CpaB Intracellular trafficking and secretion 86357030 Common - probable transcriptional regulator protein, CRP family RHE_CH01392 101 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 86359626 Common manB3 beta-mannosidase protein RHE_CH04047 42 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 86356081 Common - putative carboxyphosphonoenolpyruvate phosphonomutase protein RHE_CH00424 45 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 86359682 Common pdxK pyridoxal kinase protein RHE_CH04104 2 None None None 86357742 Common - probable inositol monophosphatase protein RHE_CH02123 170 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 86356495 Common - probable two-component sensor histidine kinase protein RHE_CH00849 206 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 86359326 Common nuoA2 NADH-ubiquinone oxidoreductase chain A protein RHE_CH03736 162 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 86356181 Common - probable cation/multidrug efflux transport protein RHE_CH00528 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 86358526 Common - hypothetical protein RHE_CH02924 6 None None None 86358741 Common - hypothetical protein RHE_CH03140 22 COG2361 COG2361, Uncharacterized conserved protein Function unknown 86359633 Common - probable oxidoreductase protein RHE_CH04054 123 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 86359661 Common dnaEch2 DNA polymerase III alpha subunit protein RHE_CH04083 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 86359668 Common - hypothetical protein RHE_CH04090 68 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 86357566 Common ispDF bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein RHE_CH01945 196 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 86358037 Common gstch9 glutathione S-transferase protein RHE_CH02424 97 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 86359562 Nonpathogen - hypothetical protein RHE_CH03983 1 None None None 86355888 Common - probable succinoglycan biosynthesis transport protein RHE_CH00229 68 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 86358847 Nonpathogen - hypothetical protein RHE_CH03248 1 None None None 86358722 Common - hypothetical protein RHE_CH03121 37 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 86356762 Common degPch1 serine protease DO-like protein RHE_CH01120 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 86357739 Common fabF2 3-oxoacyl-(acyl carrier protein) synthase II RHE_CH02120 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 86356142 Nonpathogen - hypothetical protein RHE_CH00486 1 None None None 86357214 Common - O-acetylhomoserine aminocarboxypropyltransferase RHE_CH01577 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 86356602 Common ctaE cytochrome-c oxidase, subunit III protein RHE_CH00956 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 86356537 Common - probable transcriptional accessory protein (RNA binding S1 domain) RHE_CH00891 142 COG2183 Tex, Transcriptional accessory protein Transcription 86357373 Common - probable transcriptional regulator protein, AsnC family RHE_CH01743 150 COG1522 Lrp, Transcriptional regulators Transcription 86358876 Common - putative oxidoreductase RHE_CH03277 191 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 86358232 Common - hypothetical protein RHE_CH02625 2 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 86359413 Common - hypothetical protein RHE_CH03830 100 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 86359134 Common - hypothetical conserved membrane protein RHE_CH03543 18 COG5480 COG5480, Predicted integral membrane protein Function unknown 86355911 Common aphA acetylpolyamine aminohydrolase protein RHE_CH00253 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 86355833 Common mgsA methylglyoxal synthase RHE_CH00173 88 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 86357310 Common rplV 50S ribosomal protein L22 RHE_CH01680 214 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 86359545 Common leuC isopropylmalate isomerase large subunit RHE_CH03965 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 86357584 Common mdcF malonate transporter protein RHE_CH01963 71 COG0679 COG0679, Predicted permeases General function prediction only 86356457 Nonpathogen - hypothetical protein RHE_CH00811 2 None None None 86358068 Common - hypothetical protein RHE_CH02456 32 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 86358456 Common ftsI cell division penicillin-binding protein RHE_CH02853 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 86357432 Common - hypothetical protein RHE_CH01802 55 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 86359290 Common cyaG1 adenylate cyclase protein RHE_CH03700 78 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 86357216 Common - hypothetical protein RHE_CH01579 3 None None None 86355949 Common - probable transcriptional regulator protein, AraC family RHE_CH00292 49 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 86359277 Common - putative multidrug efflux transporter protein RHE_CH03687 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 86359090 Common pgk phosphoglycerate kinase RHE_CH03499 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 86356270 Common - hypothetical protein RHE_CH00619 2 None None None 86358355 Common ugpEch1 sn-glycerol-3-phosphate ABC transporter, permease protein RHE_CH02750 142 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 86359510 Common - hypothetical protein RHE_CH03930 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 86355749 Common - probable glycine cleavage system T protein RHE_CH00088 183 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 86358129 Common - hypothetical conserved membrane protein RHE_CH02518 22 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 86356663 Common - probable oxidoreducatse protein RHE_CH01018 109 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 86357695 Common - putative ABC transporter, permease protein RHE_CH02076 209 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 86358698 Common oppB oligopeptide ABC transporter, permease protein RHE_CH03097 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 86357615 Nonpathogen - hypothetical protein RHE_CH01995 3 None None None 86355992 Common - putative protein transport protein RHE_CH00335 249 COG4618 ArpD, ABC-type protease/lipase transport system, ATPase and permease components General function prediction only 86358729 Common - hypothetical protein RHE_CH03128 4 None None None 86355671 Common - Maf-like protein RHE_CH00002 186 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 86358498 Common - probable oxidoreductase protein RHE_CH02895 66 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 86358505 Common - hypothetical protein RHE_CH02902 48 COG2942 COG2942, N-acyl-D-glucosamine 2-epimerase Carbohydrate transport and metabolism 86358837 Common rkpK UDP-glucose 6-dehydrogenase protein RHE_CH03238 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 86356821 Common - putative ATP-binding protein RHE_CH01181 76 COG0433 COG0433, Predicted ATPase General function prediction only 86359115 Nonpathogen - hypothetical protein RHE_CH03524 3 None None None 86359503 Common - probable transcriptional regulator protein, LysR family RHE_CH03922 166 COG0583 LysR, Transcriptional regulator Transcription 86357673 Common - probable sugar ABC transporter, permease protein RHE_CH02054 146 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 86358490 Common - probable amino acid transporter protein RHE_CH02887 79 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 86356501 Common fabG1 3-oxoacyl-(acyl carrier protein) reductase protein RHE_CH00855 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 86357499 Common aspB2 aspartate transaminase protein RHE_CH01873 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 86358029 Common - putative hydrolase protein RHE_CH02416 39 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 86356209 Common - probable DNA glycosylase protein RHE_CH00556 21 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 86357318 Common rpsN 30S ribosomal protein S14 RHE_CH01688 204 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 86357004 Common - hypothetical protein RHE_CH01366 10 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 86359403 Common cobT cobalamin biosynthesis protein RHE_CH03820 41 COG4547 CobT, Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase) Coenzyme metabolism 86358955 Common - probable protein secretion protein, HlyD family RHE_CH03357 140 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 86358252 Nonpathogen - hypothetical protein RHE_CH02646 3 None None None 86358205 Common - hypothetical protein RHE_CH02598 5 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 86359459 Common - putative acyltransferase protein RHE_CH03878 38 COG3176 COG3176, Putative hemolysin General function prediction only 86356295 Common cheD chemotaxis protein RHE_CH00644 87 COG1871 CheD, Chemotaxis protein; stimulates methylation of MCP proteins Cell motility and secretion / Signal transduction mechanisms 86357274 Common - hypothetical protein RHE_CH01640 170 COG0344 COG0344, Predicted membrane protein Function unknown 86356488 Common - probable inositol monophosphatase protein RHE_CH00842 181 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 86356780 Common betI transcriptional regulator BetI RHE_CH01138 73 COG1309 AcrR, Transcriptional regulator Transcription 86356492 Common lpxK tetraacyldisaccharide 4'-kinase RHE_CH00846 128 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 86358396 Common dapAch3 dihydrodipicolinate synthase protein RHE_CH02792 216 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 86358095 Common cobB cobyrinic acid a,c-diamide synthase RHE_CH02483 138 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 86358382 Common - hypothetical protein RHE_CH02778 37 COG4315 COG4315, Uncharacterized protein conserved in bacteria Function unknown 86359574 Common dppDch3 dipeptide ABC transporter, ATP-binding protein RHE_CH03995 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 86356644 Common - hypothetical protein RHE_CH00998 30 COG5389 COG5389, Uncharacterized protein conserved in bacteria Function unknown 86357943 Common - hypothetical protein RHE_CH02328 9 COG4332 COG4332, Uncharacterized protein conserved in bacteria Function unknown 86355921 Common pheS phenylalanyl-tRNA synthetase subunit alpha RHE_CH00263 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 86357443 Common xthA2 exodeoxyribonuclease III protein RHE_CH01815 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 86356585 Common dnaJ2 molecular chaperone protein, DnaJ family RHE_CH00939 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 86356559 Common dxs 1-deoxy-D-xylulose-5-phosphate synthase RHE_CH00913 227 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 86357903 Common - probable oxidoreductase protein RHE_CH02288 188 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 86355983 Common - probable amino acid efflux protein, LysE family RHE_CH00326 107 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 86357482 Common gatA aspartyl/glutamyl-tRNA amidotransferase subunit A RHE_CH01855 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 86357633 Common - hypothetical protein RHE_CH02013 5 None None None 86358365 Common - hypothetical protein RHE_CH02761 7 None None None 86357029 Common era GTP-binding protein Era RHE_CH01391 234 COG1159 Era, GTPase General function prediction only 86356615 Common - probable zinc ABC transporter, ATP-binding protein RHE_CH00969 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 86358174 Common - probable acetyltransferase protein RHE_CH02565 14 COG0456 RimI, Acetyltransferases General function prediction only 86358344 Common - probable myo-inositol-1-phosphate synthase protein RHE_CH02739 54 COG1260 INO1, Myo-inositol-1-phosphate synthase Lipid metabolism 86356256 Common appD oligopeptide ABC transporter, ATP-binding protein RHE_CH00605 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 86356482 Common - putative methylase protein RHE_CH00836 210 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 86356232 Common - hypothetical protein RHE_CH00580 21 None None None 86357681 Common dppCch2 dipeptide ABC transporter, permease protein RHE_CH02062 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 86359465 Common - putative oxidoreductase protein RHE_CH03884 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 86358966 Common - hypothetical protein RHE_CH03368 29 COG4101 COG4101, Predicted mannose-6-phosphate isomerase Carbohydrate transport and metabolism 86358987 Nonpathogen - hypothetical protein RHE_CH03389 8 None None None 86359230 Common bglSch beta-glucosidase protein RHE_CH03640 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 86355890 Nonpathogen - hypothetical protein RHE_CH00231 1 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 86359605 Common rpoH2 RNA polymerase factor sigma-32 RHE_CH04026 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 86359640 Common rplU 50S ribosomal protein L21 RHE_CH04062 206 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 86356516 Common - putative glycosyltransferase protein RHE_CH00870 15 None None None 86355918 Common infC translation initiation factor IF-3 RHE_CH00260 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 86358475 Common - probable methyltransferase transcriptional regulator protein, ArsR family RHE_CH02872 193 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 86358657 Common - hypothetical protein RHE_CH03055 33 COG5426 COG5426, Uncharacterized membrane protein Function unknown 86357581 Common cysI sulfite reductase (NADPH) protein RHE_CH01960 163 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 86356521 Common ispB octaprenyl-diphosphate synthase protein RHE_CH00875 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 86357547 Common gltA type II citrate synthase RHE_CH01926 194 COG0372 GltA, Citrate synthase Energy production and conversion 86359436 Common fdsD NAD-dependent formate dehydrogenase, delta subunit protein RHE_CH03855 26 None None None 86357065 Common - probable oxidoreductase protein RHE_CH01427 236 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 86359237 Common - probable transcriptional regulator protein, LacI family RHE_CH03647 127 COG1609 PurR, Transcriptional regulators Transcription 86358832 Common pssP exopolysaccharide polymerization protein RHE_CH03233 145 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 86355766 Common irr iron transcriptional regulator protein RHE_CH00106 148 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 86359061 Common sqdC sulfolipid biosynthesis protein RHE_CH03470 73 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 86357986 Common nadE NAD synthetase RHE_CH02371 240 COG0171 NadE, NAD synthase Coenzyme metabolism 86356545 Common - probable translation factor sua5 protein RHE_CH00899 230 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 86358840 Common - probable dioxygenase protein RHE_CH03241 37 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 86359476 Common sdhA succinate dehydrogenase flavoprotein subunit RHE_CH03895 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 86357171 Common ihfA integration host factor subunit alpha RHE_CH01533 194 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 86357976 Common - probable sugar ABC transporter, substrate-binding protein RHE_CH02361 81 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86357845 Common sugE chaperone-like transmembrane protein RHE_CH02230 127 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 86358650 Common - hypothetical protein RHE_CH03048 4 COG5466 COG5466, Predicted small metal-binding protein Function unknown 86358609 Common - probable short-chain dehydrogenase protein RHE_CH03007 238 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 86356706 Common - putative SAM-dependent methyltransferase protein RHE_CH01063 28 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 86356788 Common - hypothetical protein RHE_CH01146 9 None None None 86357884 Common - putative amino acid ABC transporter, substrate-binding protein RHE_CH02269 52 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 86356730 Common - hypothetical protein RHE_CH01087 2 None None None 86358184 Common - hypothetical protein RHE_CH02575 5 None None None 86356322 Common flaCch3 flagellin C protein RHE_CH00671 58 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 86356227 Common - hypothetical conserved membrane protein RHE_CH00574 3 None None None 86357958 Nonpathogen - hypothetical protein RHE_CH02343 1 None None None 86359583 Common - probable amino acid ABC transporter, ATP-binding protein RHE_CH04004 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 86359539 Common rpsP 30S ribosomal protein S16 RHE_CH03959 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 86357408 Nonpathogen - hypothetical protein RHE_CH01778 1 None None None 86358681 Common - probable transcriptional regulator protein, LuxR family RHE_CH03080 69 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 86359244 Common - probable transcriptional regulator protein, AraC family RHE_CH03654 132 COG3708 COG3708, Uncharacterized protein conserved in bacteria Function unknown 86358439 Nonpathogen - hypothetical protein RHE_CH02836 2 None None None 86359199 Common - putative two-component sensor histidine kinase protein RHE_CH03609 36 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 86359152 Common exoN UTP-glucose-1-phosphate uridylyltransferase protein RHE_CH03561 226 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 86357369 Nonpathogen - hypothetical protein RHE_CH01739 1 None None None 86356018 Common - putative deoxyribonucleotide triphosphate pyrophosphatase RHE_CH00361 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 86358737 Nonpathogen - hypothetical protein RHE_CH03136 4 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 86356692 Common - probable 3-oxoacyl-[acyl-carrier protein] reductase protein RHE_CH01048 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 86358325 Common - putative phenazine antibiotic biosynthesis protein RHE_CH02720 111 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 86359162 Common ibpA molecular chaperone small heat shock protein RHE_CH03571 66 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 86356798 Nonpathogen - hypothetical protein RHE_CH01158 11 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 86358169 Common - probable adenylate cyclase protein RHE_CH02560 80 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 86359491 Common - putative permease protein RHE_CH03910 152 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86358815 Common pssL exopolysaccharide polymerization and/or export protein RHE_CH03216 81 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 86356381 Common - probable exodeoxyribonuclease III protein RHE_CH00732 132 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 86359186 Common glgA glycogen synthase RHE_CH03596 133 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 86355803 Nonpathogen - hypothetical protein RHE_CH00143 1 None None None 86357079 Common - putative oxidoreductase protein RHE_CH01441 196 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 86357865 Common sufD ABC transporter involved in Fe-S cluster assembly, permease protein RHE_CH02250 170 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 86356220 Common mscL large-conductance mechanosensitive channel transmembrane protein RHE_CH00567 130 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 86357533 Common - hypothetical protein RHE_CH01912 19 None None None 86356026 Common trmB tRNA (guanine-N(7))-methyltransferase RHE_CH00369 173 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 86358850 Common - probable ABC transporter, ATP-binding protein (consisting of 2 fused ATP-binding domains) RHE_CH03251 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 86356870 Common - putative permease protein RHE_CH01230 173 COG0628 PerM, Predicted permease General function prediction only 86356721 Common - hypothetical protein RHE_CH01078 20 COG3832 COG3832, Uncharacterized conserved protein Function unknown 86356546 Common - hypothetical protein RHE_CH00900 3 None None None 86359223 Common - probable acetyltransferase protein RHE_CH03633 81 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 86359620 Common genX lysyl-tRNA synthetase protein RHE_CH04041 200 COG2269 COG2269, Truncated, possibly inactive, lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 86358407 Common - hypothetical protein RHE_CH02803 17 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 86357870 Common - putative alpha/beta hydrolase protein RHE_CH02255 87 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 86358973 Common - probable sugar ABC transporter, permease protein RHE_CH03375 150 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 86359026 Common - probable two-component sensor histidine kinase protein RHE_CH03434 208 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 86358195 Common - hypothetical protein RHE_CH02587 99 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 86358663 Common - putative glutathione S-transferase protein RHE_CH03061 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 86358908 Common - probable urease-associated protein RHE_CH03309 24 COG3813 COG3813, Uncharacterized protein conserved in bacteria Function unknown 86356592 Common pit phosphate transporter protein RHE_CH00946 166 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 86357837 Nonpathogen - hypothetical protein RHE_CH02221 1 None None None 86356419 Nonpathogen nlpE2 lipopolysaccharide biosynthesis protein RHE_CH00770 1 None None None 86357604 Common - hypothetical protein RHE_CH01984 18 COG3673 COG3673, Uncharacterized conserved protein Function unknown 86358782 Common - probable acetyltransferase protein RHE_CH03182 7 COG0456 RimI, Acetyltransferases General function prediction only 86355892 Nonpathogen - hypothetical protein RHE_CH00233 2 None None None 86357828 Common - hypothetical protein RHE_CH02212 4 None None None 86358637 Common aptch adenine phosphoribosyltransferase RHE_CH03035 194 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 86358240 Common - putative RTX toxin hemolysin-type protein RHE_CH02633 65 None None None 86359594 Common rpmF 50S ribosomal protein L32 RHE_CH04015 117 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 86356156 Common - probable acyltransferase protein RHE_CH00500 98 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 86357562 Common lipA lipoyl synthase RHE_CH01941 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 86356872 Common - putative ring-cleaving dioxygenase protein RHE_CH01232 39 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 86355694 Common - probable nuclease/helicase protein, ATP dependent RHE_CH00026 227 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 86358903 Common - probable urease-associated protein RHE_CH03304 15 None None None 86359534 Common - hypothetical protein RHE_CH03954 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 86357296 Common rplL 50S ribosomal protein L7/L12 RHE_CH01666 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 86356401 Common - probable SAM-dependent methyltransferase protein RHE_CH00752 135 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 86357307 Common rplW 50S ribosomal protein L23 RHE_CH01677 228 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 86359303 Common exsD organic-radical-activating protein RHE_CH03713 150 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 86358946 Common mexF1 multidrug-efflux system, acriflavin resistance protein RHE_CH03348 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 86357892 Common - putative sensory box/GGDEF family protein RHE_CH02277 190 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 86359381 Common - hypothetical protein RHE_CH03798 32 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 86356925 Common - hypothetical protein RHE_CH01285 5 None None None 86359253 Common - probable spermidine/putrescine ABC transporter, permease protein RHE_CH03663 125 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 86356728 Common - putative esterase protein RHE_CH01085 77 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 86356578 Common - hypothetical protein RHE_CH00932 24 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 86356132 Common otsAch trehalose-6-phosphate synthase protein RHE_CH00476 97 COG0380 OtsA, Trehalose-6-phosphate synthase Carbohydrate transport and metabolism 86357149 Common ribE riboflavin synthase subunit alpha RHE_CH01511 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 86357185 Nonpathogen - hypothetical protein RHE_CH01548 1 None None None 86358573 Common dctA C4-dicarboxylate transporter DctA RHE_CH02971 160 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 86358731 Common guaD guanine deaminase RHE_CH03130 151 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 86357106 Common - putative ABC transporter, ATP-binding protein RHE_CH01468 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 86358723 Common glpKch2 glycerol kinase protein RHE_CH03122 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 86358081 Common - probable transcriptional regulator protein, AraC family RHE_CH02469 27 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 86356502 Common - probable transcriptional regulator protein, IclR family RHE_CH00856 116 COG1414 IclR, Transcriptional regulator Transcription 86356811 Common rpsUch1 30S ribosomal protein S21 RHE_CH01171 43 None None None 86358600 Common aatAch aspartate aminotransferase RHE_CH02998 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 86356867 Common - hypothetical protein RHE_CH01227 10 None None None 86358808 Common - probable transcriptional regulator protein RHE_CH03208 42 COG1396 HipB, Predicted transcriptional regulators Transcription 86358247 Common mocEch ferredoxin of the Rieseke type protein RHE_CH02641 58 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 86357792 Common trpC indole-3-glycerol-phosphate synthase RHE_CH02175 218 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 86357225 Common clpX ATP-dependent protease ATP-binding subunit RHE_CH01588 220 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 86356464 Common - probable oxidoreductase protein RHE_CH00818 205 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 86356895 Common - hypothetical protein RHE_CH01255 12 COG5447 COG5447, Uncharacterized conserved protein Function unknown 86357543 Common fabZ (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase RHE_CH01922 186 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 86357645 Common ocdch2 ornithine cyclodeaminase protein RHE_CH02026 97 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 86356448 Common - hypothetical protein RHE_CH00802 10 COG5403 COG5403, Uncharacterized conserved protein Function unknown 86357092 Common - putative permease protein RHE_CH01454 97 COG0795 COG0795, Predicted permeases General function prediction only 86356291 Common cheW1 chemotaxis signal transduction protein RHE_CH00640 134 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 86357476 Common map1 methionine aminopeptidase RHE_CH01849 240 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 86357520 Common metC cystathionine beta-lyase RHE_CH01899 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 86359072 Common ruvA Holliday junction DNA helicase motor protein RHE_CH03481 209 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 86358303 Common - probable transcriptional regulator protein, TetR family RHE_CH02697 93 COG1309 AcrR, Transcriptional regulator Transcription 86356641 Common ccrM site-specific DNA-methyltransferase (adenine-specific) protein RHE_CH00995 143 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 86357264 Common - putative acetyltransferase protein RHE_CH01630 8 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 86358062 Common - short chain dehydrogenase RHE_CH02450 229 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 86358255 Nonpathogen - hypothetical protein RHE_CH02649 4 COG5381 COG5381, Uncharacterized protein conserved in bacteria Function unknown 86358327 Common - putative endonuclease/exonuclease/phosphatase family protein RHE_CH02722 8 COG2374 COG2374, Predicted extracellular nuclease General function prediction only 86357506 Common - hypothetical protein RHE_CH01883 34 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 86355679 Common - putative DNA repair protein, smr/mutS family RHE_CH00010 78 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 86356676 Nonpathogen - hypothetical protein RHE_CH01032 1 None None None 86356263 Common rbsBch1 ribose ABC transporter, substrate-binding protein RHE_CH00612 107 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86359524 Common acnA aconitate hydratase RHE_CH03944 223 COG1048 AcnA, Aconitase A Energy production and conversion 86358590 Common dak dihydroxyacetone kinase protein RHE_CH02988 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 86358792 Common - probable sugar ABC transporter, substrate-binding protein RHE_CH03192 64 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86358733 Common - hypothetical protein RHE_CH03132 2 None None None 86356072 Common truA tRNA pseudouridine synthase A RHE_CH00415 236 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 86357990 Common aroF aldolase DAHP synthetase protein RHE_CH02375 73 COG3200 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 86359421 Common dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase RHE_CH03839 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 86358547 Common - putative permease protein RHE_CH02945 82 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 86356752 Nonpathogen - hypothetical protein RHE_CH01110 1 None None None 86356961 Nonpathogen - hypothetical conserved membrane protein RHE_CH01321 5 None None None 86356234 Common - hypothetical protein RHE_CH00582 31 COG5328 COG5328, Uncharacterized protein conserved in bacteria Function unknown 86359322 Nonpathogen - hypothetical protein RHE_CH03732 2 None None None 86355760 Common - hypothetical protein RHE_CH00099 17 COG4530 COG4530, Uncharacterized protein conserved in bacteria Function unknown 86359335 Common nuoH2 NADH-ubiquinone oxidoreductase chain H protein RHE_CH03745 184 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 86356139 Common - probable proline/glycine betaine ABC transporter, ATP-binding protein RHE_CH00483 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 86357793 Common moaC molybdenum cofactor biosynthesis protein RHE_CH02176 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 86356700 Nonpathogen - hypothetical protein RHE_CH01056 1 None None None 86359678 Common asd aspartate-semialdehyde dehydrogenase RHE_CH04100 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 86359390 Common - hypothetical protein RHE_CH03807 11 COG4093 COG4093, Uncharacterized protein conserved in bacteria Function unknown 86358919 Common braC2 amino acid ABC transporter, substrate-binding protein RHE_CH03321 128 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 86358346 Nonpathogen - hypothetical protein RHE_CH02741 12 COG3664 XynB, Beta-xylosidase Carbohydrate transport and metabolism 86356594 Common - putative NTP pyrophosphohydrolase protein, MuT/nudix family RHE_CH00948 30 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 86355696 Common - probable nucleotidyltransferase protein RHE_CH00028 219 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 86357309 Common rpsS 30S ribosomal protein S19 RHE_CH01679 243 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 86355820 Common - probable phosphonate ABC transporter, ATP-binding protein RHE_CH00160 249 COG3638 COG3638, ABC-type phosphate/phosphonate transport system, ATPase component Inorganic ion transport and metabolism 86359314 Common - hypothetical protein RHE_CH03724 42 COG3564 COG3564, Uncharacterized protein conserved in bacteria Function unknown 86357073 Common - hypothetical conserved membrane protein RHE_CH01435 3 COG4541 COG4541, Predicted membrane protein Function unknown 86355872 Common - probable leucine aminopeptidase protein RHE_CH00213 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 162329646 Common - putative oxidoreductase protein RHE_CH00707 142 COG2081 COG2081, Predicted flavoproteins General function prediction only 86357429 Nonpathogen - hypothetical protein RHE_CH01799 1 None None None 86357817 Common folE GTP cyclohydrolase I RHE_CH02201 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 86357332 Common - putative sulfite oxidase subunit YedZ RHE_CH01702 74 COG2717 COG2717, Predicted membrane protein Function unknown 86358451 Common ftsW cell division protein RHE_CH02848 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 86359647 Common proA gamma-glutamyl phosphate reductase RHE_CH04069 188 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 86356174 Common - probable insertion sequence transposase protein RHE_CH00520 46 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 86356633 Common - probable multidrug resistance transporter protein RHE_CH00987 164 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86355924 Common - probable oxidoreductase protein, aldo/keto reductase family RHE_CH00266 200 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 86356347 Common aglE alpha-glucoside ABC transporter, substrate-binding protein RHE_CH00696 39 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86356010 Common aarF ubiquinone biosynthesis protein RHE_CH00353 183 COG0661 AarF, Predicted unusual protein kinase General function prediction only 86358360 Nonpathogen - hypothetical protein RHE_CH02755 5 None None None 86358715 Common - putative transcriptional regulator protein, PadR family RHE_CH03114 85 COG1695 COG1695, Predicted transcriptional regulators Transcription 86358624 Common - hypothetical protein RHE_CH03022 12 None None None 86359501 Common - putative stress-induced OsmC-like protein RHE_CH03920 89 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 86357322 Common rpsE 30S ribosomal protein S5 RHE_CH01692 248 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 86359204 Common - hypothetical protein RHE_CH03614 3 None None None 162329633 Common - translation-associated GTPase RHE_CH03031 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 86357141 Common - hypothetical conserved membrane protein RHE_CH01503 23 COG1714 COG1714, Predicted membrane protein/domain Function unknown 86359495 Common - putative acetyltransferase protein RHE_CH03914 63 COG0456 RimI, Acetyltransferases General function prediction only 86356301 Common flhB flagellar biosynthesis protein FlhB RHE_CH00650 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 86357361 Common xthA1 exodeoxyribonuclease III protein RHE_CH01731 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 86355786 Common dnaX DNA polymerase III subunits gamma and tau RHE_CH00126 248 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 86357701 Common - probable sugar ABC transporter, permease protein RHE_CH02082 110 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 86358154 Common ohr organic hydroperoxide resistance protein RHE_CH02544 87 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 86356325 Common motB flagellar motor protein MotB RHE_CH00674 85 COG1360 MotB, Flagellar motor protein Cell motility and secretion 86356981 Common iolE myo-inositol catabolism protein RHE_CH01342 64 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 86357707 Common - inner membrane ABC transporter permease protein YjfF RHE_CH02088 130 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 86355728 Common - hypothetical protein RHE_CH00067 2 None None None 86356205 Common - putative pyrimidine reductase protein (dihydrofolate reductase family) RHE_CH00552 72 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 86358411 Common - probable transcriptional regulator protein, AraC family RHE_CH02808 111 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 86357486 Common - probable acetyltransferase protein RHE_CH01860 8 COG0456 RimI, Acetyltransferases General function prediction only 86356543 Common - hypothetical protein RHE_CH00897 22 None None None 86358159 Common - hypothetical protein RHE_CH02550 48 COG4102 COG4102, Uncharacterized protein conserved in bacteria Function unknown 86357997 Common - hypothetical protein RHE_CH02382 74 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 86358118 Common - putative cation efflux system protein RHE_CH02506 152 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 86355691 Common accD acetyl-CoA carboxylase subunit beta RHE_CH00023 216 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 86358002 Common - putative pyridoxine biosynthesis protein RHE_CH02387 36 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 86357289 Common tufB elongation factor Tu RHE_CH01658 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 86359656 Common ctpA C-terminal processing peptidase protein RHE_CH04078 183 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 86358051 Common - probable uracil-DNA glycosylase protein RHE_CH02439 58 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 86357173 Common - putative two-component response regulator protein RHE_CH01535 72 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 86359353 Common ppiD2 peptidyl prolyl cis-trans isomerase D signal peptide protein RHE_CH03769 157 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 86357810 Common - putative nitroreductase protein RHE_CH02194 84 COG0778 NfnB, Nitroreductase Energy production and conversion 86355847 Common - probable sugar ABC transporter, ATP-binding protein RHE_CH00188 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 86359096 Common - hypothetical protein RHE_CH03505 18 COG5317 COG5317, Uncharacterized protein conserved in bacteria Function unknown 86359127 Common ggt2 gamma-glutamyltranspeptidase protein RHE_CH03536 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 86359343 Common ubiG 3-demethylubiquinone-9 3-methyltransferase RHE_CH03759 171 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 86356994 Common - hypothetical protein RHE_CH01356 13 None None None 86357708 Common - probable transcriptional regulator protein, GntR family RHE_CH02089 137 COG2186 FadR, Transcriptional regulators Transcription 86357912 Common - probable transcriptional regulator protein, GntR family RHE_CH02297 109 COG1802 GntR, Transcriptional regulators Transcription 86357875 Common - putative trehalose synthase (glycosyl hydrolase) protein RHE_CH02260 164 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 86356396 Common - hypothetical protein RHE_CH00747 7 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 86357894 Common purS phosphoribosylformylglycinamidine synthase subunit PurS RHE_CH02279 114 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 86357788 Common - hypothetical conserved membrane protein RHE_CH02171 17 COG2261 COG2261, Predicted membrane protein Function unknown 86355951 Common - putative acetyltransferase protein RHE_CH00294 15 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 86357574 Common - D-amino acid aminotransferase RHE_CH01953 199 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 86356735 Common - putative terminase small subunit protein RHE_CH01092 8 None None None 86356213 Common cspA1 cold shock protein RHE_CH00560 174 COG1278 CspC, Cold shock proteins Transcription 86358420 Common - putative serine protein kinase protein RHE_CH02817 70 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 86356376 Common traAch conjugal transfer protein A RHE_CH00726 86 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 86357132 Common cyaB adenylate cyclase protein RHE_CH01494 54 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 86356404 Common - putative glycosyl/methyltransferase hybrid protein RHE_CH00755 97 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 86358041 Common - hypothetical protein RHE_CH02428 14 COG5649 COG5649, Uncharacterized conserved protein Function unknown 86358292 Common - hypothetical protein RHE_CH02686 3 None None None 86358618 Common - hypothetical protein RHE_CH03016 34 COG5465 COG5465, Uncharacterized conserved protein Function unknown 86357550 Common - hypothetical protein RHE_CH01929 12 None None None 86359239 Common xylBch xylulokinase protein RHE_CH03649 179 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 86358765 Common gguA xylose ABC transporter, ATP-binding protein RHE_CH03164 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 86357111 Common - hypothetical protein RHE_CH01473 4 None None None 86356671 Common - hypothetical protein RHE_CH01027 22 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 86358745 Common - probable D-amino acid oxidase protein RHE_CH03144 55 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 86355817 Common - probable phosphonate ABC transporter, permease protein RHE_CH00157 84 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 86356368 Common potI spermidine/putrescine ABC transporter, permease component II protein RHE_CH00717 210 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 86356885 Common - probable molecular chaperone small heat shock protein, hsp20 family RHE_CH01245 174 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 86359542 Common rplS 50S ribosomal protein L19 RHE_CH03962 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 86357255 Common - putative lactoylglutathione lyase protein RHE_CH01621 90 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 86356903 Common - probable transcriptional regulator protein, TetR family RHE_CH01263 9 COG1309 AcrR, Transcriptional regulator Transcription 86356068 Common mcpV1 methyl-accepting chemotaxis protein RHE_CH00411 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 86355799 Common - probable acetyltransferase protein RHE_CH00139 20 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 86357017 Common - putative hydrolase protein RHE_CH01379 67 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 86355942 Common - probable arsenate reductase protein RHE_CH00284 110 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 86359486 Common hemD uroporphyrinogen-III synthase RHE_CH03905 31 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 86358031 Common - probable amino acid ABC transporter, substrate-binding protein RHE_CH02418 182 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 86356771 Nonpathogen - hypothetical protein RHE_CH01129 1 None None None 86356261 Common - probable transcriptional regulator protein RHE_CH00610 132 COG2186 FadR, Transcriptional regulators Transcription 86358215 Common - hypothetical protein RHE_CH02608 19 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 86359616 Common nagA n-acetylglucosamine-6-phosphate deacetylase protein RHE_CH04037 118 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 86356797 Common - putative phosphatidylethanolamine-binding protein RHE_CH01157 117 COG1881 COG1881, Phospholipid-binding protein General function prediction only 86358273 Common - putative two-component response regulator protein RHE_CH02667 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 86356079 Common bchE Mg-protoporphyrin IX monomethyl ester oxidative cyclase subunit protein RHE_CH00422 91 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 86358441 Common - hypothetical protein RHE_CH02838 129 COG4105 ComL, DNA uptake lipoprotein General function prediction only 86359169 Nonpathogen - hypothetical protein RHE_CH03579 2 None None None 86356062 Common - putative permease protein RHE_CH00405 107 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 86358447 Common - putative UDP-glucose 4-epimerase protein RHE_CH02844 179 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 86359587 Common - putative transporter, permease protein RHE_CH04008 70 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 86356178 Common dcd 2'-deoxycytidine 5'-triphosphate deaminase RHE_CH00524 52 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 86358513 Common - probable transcriptional regulator protein, GntR family RHE_CH02910 133 COG1802 GntR, Transcriptional regulators Transcription 86358818 Common pssI glycosyltransferase protein RHE_CH03219 122 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 86355840 Nonpathogen - hypothetical protein RHE_CH00180 1 None None None 86356281 Common - putative two-component sensor histidine kinase protein RHE_CH00630 153 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 86357621 Nonpathogen - hypothetical protein RHE_CH02001 1 None None None 86356087 Common - hypothetical protein RHE_CH00430 31 COG5343 COG5343, Uncharacterized protein conserved in bacteria Function unknown 86356284 Common - putative potassium-efflux system protein RHE_CH00633 208 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 86357414 Common nrtCch nitrate ABC transporter, ATP-binding protein RHE_CH01784 75 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 86356851 Common - probable sugar ABC transporter, permease protein RHE_CH01211 112 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 86358643 Common - hypothetical protein RHE_CH03041 7 None None None 86356023 Common iunH1 inosine-uridine preferring nucleoside hydrolase protein RHE_CH00366 88 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 86359139 Common tacA sigma-54-dependent transcriptional regulator (activator) protein RHE_CH03548 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 86357452 Common tatB sec-independent translocase RHE_CH01824 28 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 86357282 Common prfB peptide chain release factor 2 RHE_CH01648 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 86355999 Common dfp bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase RHE_CH00342 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 86355867 Common cpaF pilus assembly secretion ATP-binding protein RHE_CH00208 164 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 86358320 Nonpathogen - putative glyoxalase/bleomycin resistance-like protein RHE_CH02714 9 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 86358994 Common - hypothetical protein RHE_CH03396 7 None None None 86358881 Common malL oligosaccharide alpha-1,6-glucosidase protein RHE_CH03282 161 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 86359160 Common - probable transcriptional regulator protein, LysR family RHE_CH03569 188 COG0583 LysR, Transcriptional regulator Transcription 86358222 Common coxO cytochrome-c oxidase subunit III protein RHE_CH02615 9 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 86357980 Common - putative RNA polymerase sigma factor protein, ECF family RHE_CH02365 41 COG4941 COG4941, Predicted RNA polymerase sigma factor containing a TPR repeat domain Transcription 86358024 Common - probable stress-induced OsmC-like protein RHE_CH02411 87 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 86355913 Common - probable permease protein RHE_CH00255 103 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 86359023 Common - hypothetical protein RHE_CH03431 25 None None None 86359629 Common aceC cellobiosyl-diphosphoprenyl alpha-mannosyltransferase protein RHE_CH04050 95 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 86358599 Common - hypothetical protein RHE_CH02997 28 COG3744 COG3744, Uncharacterized protein conserved in bacteria Function unknown 86358054 Common dgkA diacylglycerol kinase protein RHE_CH02442 35 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 86356108 Common - probable proline racemase protein RHE_CH00452 49 COG3938 COG3938, Proline racemase Amino acid transport and metabolism 86359592 Common - hypothetical protein RHE_CH04013 8 COG5255 COG5255, Uncharacterized protein conserved in bacteria Function unknown 86359514 Common phhB pterin-4-alpha-carbinolamine dehydratase RHE_CH03934 91 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 86356297 Common fliF flagellar MS-ring protein RHE_CH00646 126 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 86356356 Common ordL oxidoreductase protein RHE_CH00705 126 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 86358235 Common - putative nucleoside-diphosphate-sugar epimerase dehydratase protein RHE_CH02628 71 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 86358367 Common - probable aspartate racemase protein RHE_CH02763 84 COG1794 RacX, Aspartate racemase Cell envelope biogenesis, outer membrane 86357190 Nonpathogen - hypothetical protein RHE_CH01553 3 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 86359399 Common rpmB 50S ribosomal protein L28 RHE_CH03816 141 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 86356589 Nonpathogen - hypothetical protein RHE_CH00943 1 None None None 86359274 Common - putative exopolysaccharide biosynthesis protein RHE_CH03684 46 COG3932 COG3932, Uncharacterized ABC-type transport system, permease components General function prediction only 86358464 Common djlA molecular chaperone protein, DnaJ family RHE_CH02861 71 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 86357088 Common pdxA 4-hydroxythreonine-4-phosphate dehydrogenase RHE_CH01450 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 86359690 Common acsA2 acetyl-CoA synthetase RHE_CH04112 213 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 86356119 Common fucUch1 fucose dissimilation pathway protein RHE_CH00463 32 COG4154 FucU, Fucose dissimilation pathway protein FucU Carbohydrate transport and metabolism 86358402 Common folA dihydrofolate reductase protein RHE_CH02798 142 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 86355792 Common kdsB1 3-deoxy-manno-octulosonate cytidylyltransferase RHE_CH00132 140 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 86357628 Common - hypothetical protein RHE_CH02008 9 None None None 86355947 Common - hypothetical protein RHE_CH00290 9 None None None 86358515 Common - hypothetical protein RHE_CH02912 4 None None None 86356056 Common ihfB integration host factor subunit beta RHE_CH00399 203 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 86356033 Common - putative 2-methylthioadenine synthetase (miaB-like) protein RHE_CH00376 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 86356678 Nonpathogen - hypothetical protein RHE_CH01034 1 None None None 86358820 Common pssG glycosyltransferase protein RHE_CH03221 99 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 86355870 Common - probable amino acid efflux protein, LysE family RHE_CH00211 49 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 86356041 Common - putative glyoxalase protein RHE_CH00384 25 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 86359104 Common - hypothetical protein RHE_CH03513 28 None None None 86355745 Common - probable sugar ABC transporter, permease protein RHE_CH00084 164 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 86357294 Common rplA 50S ribosomal protein L1 RHE_CH01664 240 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 86355826 Common phnH carbon-phosphorus lyase complex subunit RHE_CH00166 43 COG3625 PhnH, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 86356123 Common frcA fructose ABC transporter, ATP-binding protein RHE_CH00467 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 86357010 Common - hypothetical protein RHE_CH01372 135 None None None 86356040 Common trpS tryptophanyl-tRNA synthetase RHE_CH00383 234 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 86359046 Common serC phosphoserine aminotransferase RHE_CH03455 82 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 86358522 Nonpathogen - hypothetical protein RHE_CH02920 2 None None None 86356140 Common - probable proline/glycine betaine ABC transporter, permease protein RHE_CH00484 136 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 86356316 Common flgH flagellar basal body L-ring protein RHE_CH00665 98 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 86357720 Common - hypothetical protein RHE_CH02101 41 COG3785 COG3785, Uncharacterized conserved protein Function unknown 86356807 Common - hypothetical protein RHE_CH01167 68 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 86359443 Common - putative oxidoreductase protein RHE_CH03862 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 86356513 Common atpF2 F0F1 ATP synthase subunit B RHE_CH00867 29 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 86359298 Common - putative sugar ABC transporter, permease protein RHE_CH03708 146 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 86357074 Common dnaB replicative DNA helicase RHE_CH01436 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 86359184 Common glgBch glycogen branching enzyme RHE_CH03594 142 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 86357737 Common - putative acetyltransferase protein RHE_CH02118 13 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 86357939 Common - probable carbohydrate kinase protein RHE_CH02324 125 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 86357690 Common - probable sugar ABC transporter, ATP-binding protein RHE_CH02071 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 86357156 Common - putative oxidoreductase protein RHE_CH01518 93 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 86358581 Common nerA glycerol trinitrate reductase protein RHE_CH02979 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 86356403 Common wzt polysaccharide ABC transporter, ATP-binding protein RHE_CH00754 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 86357960 Common - hypothetical protein RHE_CH02345 186 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 86359132 Common - probable amino acid efflux protein, LysE family RHE_CH03541 109 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 86357240 Common nuoD1 NADH dehydrogenase subunit D RHE_CH01606 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 86357648 Nonpathogen - hypothetical protein RHE_CH02029 1 None None None 86358696 Common - probable alpha-glucosidase protein RHE_CH03095 160 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 86359611 Common - probable ABC transporter protein, ATP-binding and permease domains RHE_CH04032 100 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 86358486 Common parA1 chromosome partitioning protein A RHE_CH02883 63 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 86357049 Common psd phosphatidylserine decarboxylase RHE_CH01411 95 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 86356694 Nonpathogen - hypothetical protein RHE_CH01050 2 None None None 86359411 Common accA acetyl-CoA carboxylase carboxyltransferase subunit alpha RHE_CH03828 177 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 86358563 Nonpathogen - hypothetical protein RHE_CH02961 4 None None None 86358067 Common - probable oxidoreductase protein RHE_CH02455 152 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 86358878 Common - putative 1,4-alpha-glucan branching enzyme protein RHE_CH03279 149 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 86359560 Common - hypothetical protein RHE_CH03980 30 COG3760 COG3760, Uncharacterized conserved protein Function unknown 86357440 Common - probable outer membrane protein RHE_CH01812 35 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 86357967 Common - putative metallo-phosphoesterase protein RHE_CH02352 71 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 86356016 Common - putative dehydrogenase protein RHE_CH00359 31 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 86358874 Common tcrX two-component response regulator RHE_CH03275 117 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 86358079 Common - probable acetyltransferase protein RHE_CH02467 54 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 86357434 Common - hypothetical protein RHE_CH01805 9 None None None 86356530 Common aroA 3-phosphoshikimate 1-carboxyvinyltransferase protein RHE_CH00884 228 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 86358811 Common pssT1 endo-1,4-beta-xylanase protein RHE_CH03212 33 COG3693 XynA, Beta-1,4-xylanase Carbohydrate transport and metabolism 86356862 Common gcd glucose dehydrogenase (pyrroloquinoline-quinone) protein RHE_CH01222 60 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 86359292 Common - hypothetical protein RHE_CH03702 15 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 86358871 Nonpathogen - hypothetical protein RHE_CH03272 1 COG4575 ElaB, Uncharacterized conserved protein Function unknown 86356823 Common - hypothetical protein RHE_CH01183 10 None None None 86359113 Common - putative chemotaxis two-component sensor histidine kinase protein RHE_CH03522 151 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 86358210 Common kupch2 potassium transporter protein RHE_CH02603 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 86356069 Common def peptide deformylase RHE_CH00412 215 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 86358144 Common arsC arsenate reductase protein RHE_CH02534 109 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 86358436 Common - probable DNA polymerase III, epsilon subunit protein RHE_CH02833 116 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 86356843 Common sodB superoxide dismutase protein RHE_CH01203 207 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 86357356 Common - probable sugar ABC transporter, ATP-binding protein RHE_CH01726 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 86358266 Common - probable sugar ABC transporter, substrate-binding protein RHE_CH02660 65 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86358126 Nonpathogen - hypothetical protein RHE_CH02514 4 COG3038 CybB, Cytochrome B561 Energy production and conversion 86359050 Common - putative cell cycle protein MesJ/cytosine deaminase-related protein RHE_CH03459 209 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 86358102 Common cobW cobalamin biosynthesis protein RHE_CH02490 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 86355994 Common - hypothetical protein RHE_CH00337 67 COG3791 COG3791, Uncharacterized conserved protein Function unknown 86359085 Common - hypothetical protein RHE_CH03494 10 None None None 86359645 Common obgE GTPase ObgE RHE_CH04067 249 COG0536 Obg, Predicted GTPase General function prediction only 86357868 Common sufB cysteine desulfurase activator complex subunit SufB RHE_CH02253 184 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 86358933 Common - probable two-component response regulator protein RHE_CH03335 94 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 86359543 Common - putative amino acid ABC transporter, substrate-binding protein RHE_CH03963 169 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 86356308 Common - hypothetical conserved membrane protein RHE_CH00657 8 None None None 86356604 Common - probable chloranphenicol phosphotransferase protein RHE_CH00958 9 COG3896 COG3896, Chloramphenicol 3-O-phosphotransferase Defense mechanisms 86357251 Common nuoM1 NADH dehydrogenase subunit M RHE_CH01617 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 86357991 Nonpathogen - hypothetical protein RHE_CH02376 8 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 86358492 Common - probable transcriptional regulator protein, RpiR family RHE_CH02889 88 COG1737 RpiR, Transcriptional regulators Transcription 86355969 Common - probable NADH dehydrogenase/NADH dehydrogenase (ubiquinone) protein RHE_CH00312 112 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 86357006 Common - probable aminotransferase protein (involved in cell wall biogenesis) RHE_CH01368 194 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 86358777 Nonpathogen - hypothetical protein RHE_CH03177 1 None None None 86357613 Common - probable resolvase protein RHE_CH01993 108 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 86358203 Nonpathogen - hypothetical protein RHE_CH02596 1 None None None 86357396 Common cpdB bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein RHE_CH01766 132 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 86359401 Nonpathogen - hypothetical protein RHE_CH03818 12 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 86359667 Common - hypothetical protein RHE_CH04089 3 None None None 86356834 Common - probable adenylate cyclase protein RHE_CH01194 77 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 86358254 Common - putative transcriptional regulator protein RHE_CH02648 135 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 86358287 Common - probable ferrichrome ABC transporter, permease protein RHE_CH02681 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 86357493 Common - hypothetical protein RHE_CH01867 11 COG4714 COG4714, Uncharacterized membrane-anchored protein conserved in bacteria Function unknown 86358007 Common moaA molybdenum cofactor biosynthesis protein A RHE_CH02392 205 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 86355881 Common - putative peptidase protein RHE_CH00222 51 COG3191 DmpA, L-aminopeptidase/D-esterase Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 86358621 Common - hypothetical protein RHE_CH03019 95 COG1565 COG1565, Uncharacterized conserved protein Function unknown 86357764 Common - aminotransferase RHE_CH02145 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 86358426 Nonpathogen - hypothetical protein RHE_CH02823 2 None None None 86355688 Common trpF N-(5'-phosphoribosyl)anthranilate isomerase RHE_CH00020 197 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 86356954 Common - probable diacylglycerol kinase protein RHE_CH01314 44 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 86359631 Common - probable transcriptional regulator protein, LysR family RHE_CH04052 168 COG0583 LysR, Transcriptional regulator Transcription 86357672 Common - probable sugar ABC transporter, substrate-binding protein RHE_CH02053 64 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86356550 Common - probable magnesium and cobalt transporter protein RHE_CH00904 44 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 86358336 Common - hypothetical protein RHE_CH02731 6 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 86356655 Common - probable polyhydroxybutyrate depolymerase protein RHE_CH01009 41 COG3509 LpqC, Poly(3-hydroxybutyrate) depolymerase Secondary metabolites biosynthesis, transport, and catabolism 86356095 Common rnpA ribonuclease P RHE_CH00438 59 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 86356374 Common rzcA rhizobiocin/RTX toxin and hemolysin-type calcium binding protein RHE_CH00724 157 None None None 86356336 Common fliQ flagellar biosynthesis protein FliQ RHE_CH00685 124 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 86358306 Common - putative nucleotidyltransferase protein RHE_CH02700 5 None None None 86358910 Common ureD urease accessory protein RHE_CH03311 76 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 86357715 Common - putative redox protein RHE_CH02096 41 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 86359214 Common - probable creatinine amidohydrolase (creatininase) protein RHE_CH03624 84 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 86359607 Common - putative transporter, permease protein RHE_CH04028 221 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86358454 Common murF UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D -alanyl-D-alanine synthetase protein RHE_CH02851 205 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 86355781 Common - probable acetyltransferase protein RHE_CH00121 28 COG0456 RimI, Acetyltransferases General function prediction only 86357872 Common anmK anhydro-N-acetylmuramic acid kinase RHE_CH02257 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 86358227 Nonpathogen - hypothetical protein RHE_CH02620 6 None None None 86358278 Common - hypothetical protein RHE_CH02672 29 COG4312 COG4312, Uncharacterized protein conserved in bacteria Function unknown 86356273 Common - putative transporter permease protein RHE_CH00622 92 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 86357342 Common - probable transcriptional regulator protein, LysR family RHE_CH01712 172 COG0583 LysR, Transcriptional regulator Transcription 86357445 Common dgt deoxyguanosinetriphosphate triphosphohydrolase-like protein RHE_CH01817 161 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 86359036 Common pobA 4-hydroxybenzoate 3-monooxygenase RHE_CH03444 47 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 86356524 Common mntH manganese transport protein MntH RHE_CH00878 102 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 86356564 Nonpathogen - putative thioesterase protein RHE_CH00918 2 COG0824 FcbC, Predicted thioesterase General function prediction only 86357530 Common - hypothetical protein RHE_CH01909 81 COG3146 COG3146, Uncharacterized protein conserved in bacteria Function unknown 86356941 Nonpathogen - hypothetical protein RHE_CH01301 2 None None None 86357726 Common uvrA excinuclease ABC subunit A RHE_CH02107 244 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 86355858 Common - hypothetical protein RHE_CH00199 14 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 86357744 Common afuB1 iron(III) ABC transporter, permease protein RHE_CH02125 223 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 86355835 Common - probable peptide ABC transporter, substrate-binding protein RHE_CH00175 167 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 86358415 Common - probable acriflavin resistance (multidrug efflux transporter) protein RHE_CH02812 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 86355904 Common nodL maltose O-acetyltransferase protein RHE_CH00246 76 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 86357730 Nonpathogen - hypothetical protein RHE_CH02111 1 None None None 86355966 Common gstch2 glutathione S-transferase protein RHE_CH00309 91 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 86357463 Common - hypothetical protein RHE_CH01835 3 None None None 86358538 Nonpathogen - hypothetical protein RHE_CH02936 1 None None None 86357334 Common ilvDch1 dihydroxy-acid dehydratase RHE_CH01704 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 86359680 Common - putative cellulose biosynthesis transcriptional regulator protein RHE_CH04102 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 86358357 Common ugpBch1 sn-glycerol-3-phosphate ABC transporter, substrate-binding protein RHE_CH02752 86 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 86355829 Common gpmA phosphoglyceromutase RHE_CH00169 173 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 86355955 Common pfs 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase RHE_CH00298 25 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 86356080 Common ada methylated-DNA-[protein]-cysteine S-methyltransferase protein RHE_CH00423 203 COG2169 Ada, Adenosine deaminase Nucleotide transport and metabolism 86357238 Common nuoC1 NADH dehydrogenase subunit C RHE_CH01604 177 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 86358616 Common csaA methionine--tRNA ligase protein RHE_CH03014 104 COG0073 ARC1, EMAP domain General function prediction only 86356435 Common ftsJ cell division protein RHE_CH00789 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 86357223 Common - putative sensory box/GGDEF family protein RHE_CH01586 166 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 86358558 Common - hypothetical protein RHE_CH02956 152 COG1610 COG1610, Uncharacterized conserved protein Function unknown 86359397 Common - hypothetical protein RHE_CH03814 77 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 86357051 Common - hypothetical protein RHE_CH01413 10 COG3832 COG3832, Uncharacterized conserved protein Function unknown 86359242 Common - probable multidrug resistance efflux protein RHE_CH03652 156 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 86357881 Common - putative hydrolase protein, MutT/nudix family RHE_CH02266 18 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 86358280 Common - short chain dehydrogenase RHE_CH02674 234 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 86358868 Common hmuT hemin transport system, hemin-binding protein RHE_CH03269 138 COG4558 ChuT, ABC-type hemin transport system, periplasmic component Inorganic ion transport and metabolism 86357490 Common - putative acetyltransferase protein RHE_CH01864 22 COG3153 COG3153, Predicted acetyltransferase General function prediction only 86358463 Common - probable N-acetylmuramoyl-L-alanine amidase protein RHE_CH02860 112 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 86359078 Common - probable small-conductance mechanosensitive channel transmembrane protein RHE_CH03487 120 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 86359358 Common - probable oxidoreductase (aldo/keto reductase) protein RHE_CH03774 207 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 86356877 Common usg usg protein (probable subunit of phosphoribosylanthranilate isomerase protein) RHE_CH01237 24 COG5425 COG5425, Usg protein, probable subunit of phosphoribosylanthranilate isomerase Amino acid transport and metabolism 86357058 Common pipch1 proline iminopeptidase protein RHE_CH01420 106 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 86359328 Common nuoC2 NADH-ubiquinone oxidoreductase chain C protein RHE_CH03738 175 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 86357560 Common - hypothetical conserved membrane protein RHE_CH01939 25 None None None 86356229 Nonpathogen - hypothetical protein RHE_CH00576 1 None None None 86357095 Common - DNA polymerase III subunit chi RHE_CH01457 46 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 86356186 Common - probable amino acid ABC transporter, substrate-binding protein RHE_CH00533 154 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 86358164 Nonpathogen - hypothetical protein RHE_CH02555 2 None None None 86355804 Common dnaJ1 molecular chaperone protein, DnaJ family RHE_CH00144 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 86358901 Common ureE urease accessory protein RHE_CH03302 62 COG2371 UreE, Urease accessory protein UreE Posttranslational modification, protein turnover, chaperones 86357312 Common rplP 50S ribosomal protein L16 RHE_CH01682 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 86358845 Common - putative endonuclease/exonuclease/phosphatase family protein RHE_CH03246 8 COG3021 COG3021, Uncharacterized protein conserved in bacteria Function unknown 86358961 Common - putative FMNH2-dependent monooxygenase protein RHE_CH03363 31 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 86358944 Common - putative acetyltransferase protein RHE_CH03346 33 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 86359154 Common - hypothetical protein RHE_CH03563 28 COG2845 COG2845, Uncharacterized protein conserved in bacteria Function unknown 162329629 Common ampC beta-lactamase RHE_CH03194 86 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 86355865 Common cpaD pilus assembly protein RHE_CH00206 15 COG5461 COG5461, Type IV pili component Cell motility and secretion 86356191 Common - hypothetical protein RHE_CH00538 7 None None None 86355738 Common - putative oxidoreducatse protein RHE_CH00077 168 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 86356383 Nonpathogen - hypothetical protein RHE_CH00734 1 None None None 86358224 Common coxM cytochrome-c oxidase subunit II protein RHE_CH02617 144 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 86357809 Common - hypothetical protein RHE_CH02193 87 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 86358735 Common - putative hydrolase protein RHE_CH03134 68 COG2267 PldB, Lysophospholipase Lipid metabolism 86357300 Common rpsL 30S ribosomal protein S12 RHE_CH01670 238 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 86356222 Common galE2 UDP-glucose 4-epimerase protein RHE_CH00569 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 86359466 Common - hypothetical protein RHE_CH03885 5 None None None 86358193 Common - hypothetical protein RHE_CH02585 60 COG2354 COG2354, Uncharacterized protein conserved in bacteria Function unknown 86357821 Common - hypothetical conserved membrane protein RHE_CH02205 87 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 86358774 Common xylH xylose ABC transporter, permease protein RHE_CH03173 109 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 86357531 Common - probable glycerophosphoryl diester phosphodiesterase protein RHE_CH01910 124 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 86359701 Common trmE tRNA modification GTPase TrmE RHE_CH04123 213 COG0486 ThdF, Predicted GTPase General function prediction only 86356614 Common - probable peroxiredoxin protein RHE_CH00968 81 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 86356476 Common - putative hydrolase, haloacid dehalogenase-like family protein RHE_CH00830 79 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 86356134 Common fadD acyl-CoA synthetase RHE_CH00478 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 86357835 Common def2 peptide deformylase RHE_CH02219 202 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 86356154 Common - putative multidrug transport protein RHE_CH00498 230 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86357774 Common - putative deoxyribonuclease protein, TatD family RHE_CH02156 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 86356680 Nonpathogen - hypothetical protein RHE_CH01036 1 None None None 86358242 Nonpathogen - hypothetical protein RHE_CH02635 1 None None None 86356165 Common pstA phosphate ABC transporter, permease protein RHE_CH00511 221 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 86356927 Common feuQ two-component sensor histidine kinase protein RHE_CH01287 207 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 86355705 Common pckA phosphoenolpyruvate carboxykinase RHE_CH00037 98 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 86358791 Common - putative UDP-glucose 4-epimerase protein RHE_CH03191 79 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 86359251 Common - probable spermidine/putrescine ABC transporter, ATP-binding protein RHE_CH03661 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 86356665 Common - putative negative regulator protein PspA (suppresses sigma54-dependent transcription) RHE_CH01020 18 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 86357754 Common - putative transporter, permease protein RHE_CH02135 96 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 86358760 Common - hypothetical protein RHE_CH03159 37 COG3744 COG3744, Uncharacterized protein conserved in bacteria Function unknown 86359044 Common - hypothetical protein RHE_CH03453 9 None None None 86357890 Common - hypothetical conserved membrane protein RHE_CH02275 39 COG5473 COG5473, Predicted integral membrane protein Function unknown 86357594 Common htpX1 protease protein, heat-shock-like RHE_CH01974 183 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 86359098 Common - probable multidrug ABC transporter, ATP-binding protein RHE_CH03507 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 86359140 Common pepF oligoendopeptidase F protein RHE_CH03549 89 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 86359585 Common - probable amino acid ABC transporter, substrate-binding protein RHE_CH04006 188 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 86358953 Common - 3-methyladenine DNA glycosylase RHE_CH03355 83 COG2094 Mpg, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 86359505 Common - probable oxidoreductase protein RHE_CH03925 228 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 86357843 Common - putative acetyltransferase protein RHE_CH02228 73 COG2153 ElaA, Predicted acyltransferase General function prediction only 86356447 Common - hypothetical protein RHE_CH00801 3 None None None 86357945 Common - putative phosphohistidine phosphatase protein RHE_CH02330 73 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 86359232 Common - probable oxidoreductase protein RHE_CH03642 118 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 86356971 Common hisCch1 histidinol-phosphate aminotransferase RHE_CH01331 222 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 86357956 Common - probable isochorismatase protein RHE_CH02341 112 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 86356207 Common - putative permease protein RHE_CH00554 116 COG0730 COG0730, Predicted permeases General function prediction only 86356557 Common tlyA hemolysin protein RHE_CH00911 132 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 86358405 Common - hypothetical protein RHE_CH02801 12 None None None 86358384 Common - hypothetical conserved membrane protein RHE_CH02780 26 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 86359002 Common - probable transcriptional regulator protein, TetR family RHE_CH03410 66 COG1309 AcrR, Transcriptional regulator Transcription 86355897 Common - probable insertion sequence transposase protein RHE_CH00238 52 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 86359063 Common - hypothetical protein RHE_CH03472 81 COG1692 COG1692, Uncharacterized protein conserved in bacteria Function unknown 86356642 Common - probable hydrolase protein RHE_CH00996 53 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 86357212 Nonpathogen - hypothetical protein RHE_CH01575 1 None None None 86356687 Common - probable two-component response regulator protein RHE_CH01043 218 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 86359173 Common - hypothetical protein RHE_CH03583 25 None None None 86357480 Common - metal-dependent hydrolase RHE_CH01853 83 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 86358249 Common mocFch ferredoxin reductase protein RHE_CH02643 231 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 86359438 Common fdsA formate dehydrogenase, alpha subunit protein RHE_CH03857 215 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 86358093 Common cobD cobalamin biosynthesis protein RHE_CH02481 147 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 86356254 Common - putative N-acetylneuraminate lyase subunit protein RHE_CH00603 36 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 86358821 Common pssF glycosyltransferase protein RHE_CH03222 97 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 86356428 Common - probable insertion sequence transposase protein RHE_CH00779 52 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 86359309 Common - probable heavy metal-transporting ATPase protein RHE_CH03719 231 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 86356237 Common maf Maf-like protein RHE_CH00585 197 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 86357936 Common - probable transcriptional regulator protein, AraC family RHE_CH02321 91 COG3449 COG3449, DNA gyrase inhibitor DNA replication, recombination, and repair 86359535 Common dapF diaminopimelate epimerase RHE_CH03955 182 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 86358655 Common - hypothetical protein RHE_CH03053 64 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 86356916 Common - hypothetical protein RHE_CH01276 27 COG5349 COG5349, Uncharacterized protein conserved in bacteria Function unknown 86358390 Common - hypothetical conserved membrane protein RHE_CH02786 25 COG5528 COG5528, Predicted integral membrane protein Function unknown 86357345 Common - hypothetical protein RHE_CH01715 56 COG2128 COG2128, Uncharacterized conserved protein Function unknown 86358316 Common znuB zinc uptake ABC transporter, permease protein RHE_CH02710 196 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 86358964 Common - putative hydroxypyruvate isomerase protein RHE_CH03366 86 COG3622 Hfi, Hydroxypyruvate isomerase Carbohydrate transport and metabolism 86357905 Common - putative 5-carboxymethyl-2-hydroxymuconate delta isomerase protein RHE_CH02290 6 COG3232 HpaF, 5-carboxymethyl-2-hydroxymuconate isomerase Amino acid transport and metabolism 86359572 Common dppBch3 dipeptide ABC transporter, permease protein RHE_CH03993 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 86355899 Common - hypothetical protein RHE_CH00240 5 None None None 86358301 Common - putative exported protein, TonB-dependent receptor protein RHE_CH02695 84 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 86356631 Common - probable cytochrome-c oxidase protein RHE_CH00985 60 COG2863 COG2863, Cytochrome c553 Energy production and conversion 86358980 Common - probable glycosyltransferase protein RHE_CH03382 122 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 86355729 Common - probable dTDP-glucose 4,6-dehydratase protein RHE_CH00068 231 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 86356455 Common glcE glycolate oxidase subunit E protein RHE_CH00809 158 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 86358975 Common - probable sugar-processing enzyme, possibly aminotransferase protein RHE_CH03377 39 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 86358186 Common - probable two-component response regulator protein RHE_CH02577 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 86356169 Common - hypothetical protein RHE_CH00515 33 COG5352 COG5352, Uncharacterized protein conserved in bacteria Function unknown 86358545 Common - hypothetical protein RHE_CH02943 52 COG2343 COG2343, Uncharacterized protein conserved in bacteria Function unknown 86355883 Common - hypothetical protein RHE_CH00224 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 86356241 Common - hypothetical protein RHE_CH00590 64 COG2353 COG2353, Uncharacterized conserved protein Function unknown 86356723 Common - hypothetical protein RHE_CH01080 10 None None None 86357697 Common fpr ferredoxin-NADP+ reductase protein RHE_CH02078 104 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 86356897 Nonpathogen - hypothetical protein RHE_CH01257 1 None None None 86359418 Common - hypothetical protein RHE_CH03836 6 None None None 86356782 Common - hypothetical protein RHE_CH01140 3 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 86356423 Common - probable insertion sequence transposase protein RHE_CH00774 52 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 86358018 Common - probable short chain dehydrogenase protein RHE_CH02403 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 86359471 Common sucC succinyl-CoA synthetase subunit beta RHE_CH03890 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 86359478 Common sdhC succinate dehydrogenase cytochrome B-556 subunit protein RHE_CH03897 69 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 86358631 Common - probable acetyltransferase protein RHE_CH03029 22 COG3393 COG3393, Predicted acetyltransferase General function prediction only 86359693 Common - hypothetical protein RHE_CH04115 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 86358645 Common - probable tRNA/rRNA methyltransferase protein RHE_CH03043 166 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 86359287 Common dgoA galactonate dehydratase protein RHE_CH03697 125 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 86359225 Common eda keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase RHE_CH03635 124 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 86356248 Common - hypothetical conserved membrane protein RHE_CH00597 19 COG2259 COG2259, Predicted membrane protein Function unknown 86357401 Common - hypothetical protein RHE_CH01771 11 None None None 86358830 Common rapAch autoaggregation protein RHE_CH03231 34 None None None 86356760 Common - probable RNA polymerase sigma factor protein, ECF family RHE_CH01118 75 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 86358958 Common mexE2 multidrug-efflux system secretion protein, HlyD family RHE_CH03360 153 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 86357564 Common - hypothetical protein RHE_CH01943 102 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 86356539 Common - probable phosphoglycerate mutase protein RHE_CH00893 130 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 86357027 Common lepB signal peptidase I protein RHE_CH01389 212 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 86357067 Common cvpA colicin V production protein RHE_CH01429 28 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 86357034 Common - hypothetical protein RHE_CH01396 53 COG3217 COG3217, Uncharacterized Fe-S protein General function prediction only