Syntrophus aciditrophicus SB, complete genome NC_007759 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 85860717 Nonpathogen - hypothetical cytosolic protein SYN_02405 1 None None None 85859754 Nonpathogen - hypothetical membrane protein SYN_01417 1 None None None 85859829 Nonpathogen - hypothetical cytosolic protein SYN_00444 1 None None None 85858008 Common - ABC-type tungstate transport system, solute-binding protein SYN_00837 62 COG2998 TupB, ABC-type tungstate transport system, permease component Coenzyme metabolism 85860614 Common - tolQ protein SYN_01053 143 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 85858272 Common - glycosyltransferase SYN_01101 202 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 85858296 Common - hypothetical protein SYN_02605 17 COG3866 PelB, Pectate lyase Carbohydrate transport and metabolism 85860059 Common - DNA repair protein SYN_01535 81 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 85858314 Nonpathogen - hypothetical membrane protein SYN_00254 1 None None None 85858458 Nonpathogen - hypothetical cytosolic protein SYN_02233 1 None None None 85859625 Common - type I secretion outer membrane protein SYN_02462 140 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 85860707 Nonpathogen - hypothetical membrane protein SYN_02415 3 None None None 85859371 Common - tRNA(Ile)-lysidine synthetase SYN_02776 239 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 85859968 Common dapF diaminopimelate epimerase SYN_00706 197 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 85858884 Nonpathogen - hypothetical cytosolic protein SYN_03175 1 None None None 85859323 Common - signal transduction histidine kinase SYN_02531 223 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 85858080 Common - glutaconyl-CoA decarboxylase beta subunit SYN_01431 56 COG1883 OadB, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit Energy production and conversion 85860264 Nonpathogen - hypothetical cytosolic protein SYN_02505 1 None None None 85859502 Common - hypothetical cytosolic protein SYN_01844 7 COG0433 COG0433, Predicted ATPase General function prediction only 85859838 Nonpathogen - hypothetical membrane protein SYN_00454 1 COG4795 PulJ, Type II secretory pathway, component PulJ Intracellular trafficking and secretion 85859475 Nonpathogen - hypothetical cytosolic protein SYN_03050 1 None None None 85859139 Common - flp pilus assembly protein, secretin SYN_01492 140 COG4964 CpaC, Flp pilus assembly protein, secretin CpaC Intracellular trafficking and secretion 85860506 Common - type IV secretion SYN_01772 142 COG4796 HofQ, Type II secretory pathway, component HofQ Intracellular trafficking and secretion 85860256 Common - ferridoxin SYN_02497 66 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 85859428 Common - transcription elongation factor SYN_01033 95 COG0782 GreA, Transcription elongation factor Transcription 85859254 Common - ABC-type molybdate transport system, permease component SYN_00270 226 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 85858582 Common - transposase SYN_03134 11 None None None 85860876 Common - 2Fe-2S and 4Fe-4S iron-sulfur protein SYN_01649 182 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 85860598 Common - signal transduction histidine kinase with PAS domain SYN_01291 156 COG3287 COG3287, Uncharacterized conserved protein Function unknown 85858087 Common - signal transduction histidine kinase SYN_01438 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 85859009 Common - hypothetical membrane protein SYN_03514 71 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 85859903 Nonpathogen - hypothetical cytosolic protein SYN_03667 1 None None None 85860892 Nonpathogen - hypothetical cytosolic protein SYN_01634 1 None None None 85858595 Common - hypothetical cytosolic protein SYN_02962 7 None None None 85859285 Common - tetratricopeptide repeat family protein SYN_02167 26 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 85860801 Common - (s)-2-hydroxy-acid oxidase chain D SYN_00316 202 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 85858270 Common - glycosyltransferase SYN_01103 207 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 85858813 Common - sigma-54 dependent transcriptional regulator SYN_01466 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 85859421 Nonpathogen - hypothetical protein SYN_03570 1 None None None 85860389 Common - Co/Zn/Cd cation transporter SYN_01172 139 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 85858462 Nonpathogen - hypothetical cytosolic protein SYN_02230 1 None None None 85857863 Common - hydrolase of the alpha/beta superfamily SYN_01206 53 COG2267 PldB, Lysophospholipase Lipid metabolism 85859525 Common - hypothetical protein SYN_01867 29 None None None 85858217 Nonpathogen - hypothetical cytosolic protein SYN_01154 9 None None None 85860703 Common - aldehyde dehydrogenase (ferredoxin), chain A SYN_02419 57 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 85859258 Common - molybdopterin biosynthesis protein SYN_00266 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 85858677 Nonpathogen - hypothetical membrane protein SYN_02925 1 None None None 85859638 Nonpathogen - hypothetical cytosolic protein SYN_03607 1 None None None 85859721 Common - SSU ribosomal protein S18P SYN_00643 212 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 85860049 Common - protein translocase subunit SYN_01524 221 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 85858400 Nonpathogen - phage protein SYN_03381 1 None None None 85858853 Common - transposase SYN_03171 66 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 85859488 Common - hypothetical cytosolic protein SYN_01828 19 COG3311 AlpA, Predicted transcriptional regulator Transcription 85859338 Common - phosphate regulon sensor protein SYN_00061 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 85860724 Common - isochorismate synthase SYN_02398 223 COG1169 MenF, Isochorismate synthase Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism 85858282 Common - anthranilate phosphoribosyltransferase SYN_02590 219 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 85859713 Nonpathogen - hypothetical cytosolic protein SYN_01973 1 None None None 85860433 Common - hypothetical cytosolic protein SYN_02692 22 COG4453 COG4453, Uncharacterized protein conserved in bacteria Function unknown 85859694 Common - signal transduction histidine kinase SYN_01094 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 85860762 Common - DNA polymerase V subunit SYN_00359 171 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 85859418 Common - pyruvate carboxylase biotin carboxylase subunit SYN_01041 234 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 85857937 Nonpathogen - hypothetical protein SYN_00148 1 None None None 85859279 Common - dihydrodipicolinate reductase SYN_02162 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 85858396 Common - mu-like prophage Flumu protein gp36 SYN_02296 19 COG4387 COG4387, Mu-like prophage protein gp36 Function unknown 85859724 Common - replicative DNA helicase SYN_00640 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 85859958 Nonpathogen - hypothetical cytosolic protein SYN_00697 4 None None None 85859415 Common - hypothetical cytosolic protein SYN_02931 188 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 85860559 Common - glycogen debranching enzyme/alpha-amylase SYN_00295 89 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 85858578 Common - tyrosyl-tRNA synthetase SYN_02977 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 85858626 Nonpathogen - hypothetical cytosolic protein SYN_03139 1 None None None 85858325 Common - cytidine deaminase SYN_03352 43 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 85859663 Common - phospho-2-dehydro-3-deoxyheptanoate aldolase SYN_01940 187 COG2876 AroA, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 85859959 Nonpathogen - hypothetical cytosolic protein SYN_00698 5 COG2946 COG2946, Putative phage replication protein RstA DNA replication, recombination, and repair 85858621 Nonpathogen - hypothetical membrane protein SYN_00199 3 None None None 85860690 Common - hypothetical lipoprotein SYN_02433 34 COG2121 COG2121, Uncharacterized protein conserved in bacteria Function unknown 85860438 Common - o-acetyltransferase SYN_02687 180 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 85859385 Common - bacterial peptide Chain Release Factor 2 (RF-2) SYN_02790 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 85860685 Common - export ABC transporter permease protein SYN_00244 164 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 85859245 Nonpathogen - hypothetical cytosolic protein SYN_00278 2 None None None 85860192 Common - asnC family transcription regulatory protein SYN_00582 53 COG1522 Lrp, Transcriptional regulators Transcription 85858613 Nonpathogen - hypothetical cytosolic protein SYN_03431 3 COG1359 COG1359, Uncharacterized conserved protein Function unknown 85859111 Common - phosphomethylpyrimidine kinase / hydroxymethylpyrimidine kinase SYN_01521 219 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 85860003 Nonpathogen - hypothetical cytosolic protein SYN_03691 1 None None None 85858360 Nonpathogen - hypothetical cytosolic protein SYN_02331 2 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 85860660 Common - sucrose phosphorylase SYN_02630 131 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 85860584 Common - hypothetical cytosolic protein SYN_02473 98 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 85860662 Common - alpha,alpha-trehalose-phosphate synthase (UDP-forming) SYN_02628 96 COG0380 OtsA, Trehalose-6-phosphate synthase Carbohydrate transport and metabolism 85858879 Nonpathogen - hypothetical cytosolic protein SYN_01312 1 None None None 85858872 Common - transposase and inactivated derivatives SYN_01318 38 None None None 85859893 Nonpathogen - hypothetical protein SYN_00506 1 None None None 85860418 Common - RNA 3'-terminal phosphate cyclase SYN_00093 47 COG0430 RCL1, RNA 3'-terminal phosphate cyclase RNA processing and modification 85859058 Common - RNA polymerase sigma-54 factor SYN_00945 145 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 85860946 Common - formamidopyrimidine-DNA glycosylase SYN_00204 182 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 85857874 Common - hypothetical cytosolic protein SYN_03261 22 COG1483 COG1483, Predicted ATPase (AAA+ superfamily) General function prediction only 85858723 Nonpathogen - hypothetical membrane protein SYN_00191 4 None None None 85858477 Common - F0F1 ATP synthase subunit beta SYN_00544 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 85860888 Common - transposase SYN_01637 69 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 85858514 Common - 4-amino-4-deoxychorismate lyase SYN_01734 194 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 85858156 Common - SSU ribosomal protein S17P SYN_03256 221 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 85859272 Common - acetylornithine aminotransferase SYN_02155 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 85858581 Common - reverse transcriptase SYN_02976 73 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 85858768 Common - helix-turn-helix DNA binding protein SYN_02733 22 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 85860211 Common - formate dehydrogenase major subunit SYN_00603 179 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 85860052 Common - signal peptidase I SYN_01527 207 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 85860147 Common engA GTP-binding protein EngA SYN_00791 234 COG1160 COG1160, Predicted GTPases General function prediction only 85860303 Common - sulfite reductase, assimilatory-type SYN_01225 161 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 85859614 Common - nicotinate-nucleotide adenylyltransferase SYN_02003 179 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 85858646 Nonpathogen - hypothetical membrane protein SYN_01749 1 None None None 85860269 Common - serine phosphatase regulator of sigma subunit SYN_02510 111 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 85860606 Nonpathogen - hypothetical cytosolic protein SYN_01046 14 COG2014 COG2014, Uncharacterized conserved protein Function unknown 85858788 Common - hypothetical membrane protein SYN_02715 5 None None None 85860860 Common - antibiotic export ATP-binding protein SYN_01666 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 85860769 Common - ferridoxin SYN_00352 82 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 85859566 Common groEL chaperonin GroEL SYN_01909 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 85860634 Common - cob(I)alamin adenosyltransferase SYN_01073 142 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 85859276 Nonpathogen - hypothetical membrane protein SYN_02159 3 None None None 85860220 Common - predicted acetyltransferase/acyltransferase SYN_00615 198 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 85859020 Common - phosphoserine aminotransferase SYN_00124 59 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 85858357 Nonpathogen - hypothetical cytosolic protein SYN_02334 1 None None None 85857993 Common - protein involved in formate dehydrogenase formation SYN_00636 33 COG3058 FdhE, Uncharacterized protein involved in formate dehydrogenase formation Posttranslational modification, protein turnover, chaperones 85857981 Common - hydrolase SYN_00624 22 COG4087 COG4087, Soluble P-type ATPase General function prediction only 85858287 Nonpathogen - transposase SYN_02596 1 None None None 85858926 Common - oxalate/formate antiporter SYN_02140 115 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 85859861 Common - hypothetical protein SYN_00476 64 COG1641 COG1641, Uncharacterized conserved protein Function unknown 85858194 Common - hypothetical protein SYN_00511 78 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 85859764 Nonpathogen - hypothetical cytosolic protein SYN_01306 1 None None None 85858263 Nonpathogen - hypothetical membrane protein SYN_01110 1 None None None 85858410 Common - hypothetical cytosolic protein SYN_02282 5 None None None 85860601 Common - isochorismatase SYN_01294 90 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 85860670 Common - o-succinylbenzoic acid--CoA ligase SYN_02620 221 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 85858863 Nonpathogen - hypothetical cytosolic protein SYN_01328 1 None None None 85860413 Common - 3-isopropylmalate dehydrogenase SYN_00088 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 85859027 Nonpathogen - hypothetical cytosolic protein SYN_03516 1 None None None 85859007 Nonpathogen - hypothetical membrane protein SYN_03189 1 None None None 85859053 Common - 2-dehydro-3-deoxyphosphooctonate aldolase SYN_00950 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 85858660 Common - ATP-dependent endonuclease family protein SYN_02907 21 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 85859430 Common - ribosomal protein S2 SYN_01032 226 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 85860871 Common - enoyl-CoA hydratase/isomerase family protein SYN_01654 161 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 85860783 Nonpathogen - hypothetical cytosolic protein SYN_00337 1 COG0316 IscA, Uncharacterized conserved protein Function unknown 85858384 Common - hypothetical cytosolic protein SYN_03377 6 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 85860357 Common - transmembrane symporter SYN_00846 42 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 85858142 Common - ribosomal protein S12 SYN_03311 214 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 85858471 Common - rod shape-determining protein SYN_00550 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 85860076 Nonpathogen - hypothetical membrane protein SYN_01552 4 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 85860997 Common - paraquat-inducible protein B SYN_02068 77 COG3008 PqiB, Paraquat-inducible protein B General function prediction only 85860837 Common - ABC transporter permease protein SYN_01690 146 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 85860538 Nonpathogen - hypothetical protein SYN_03781 1 None None None 85857953 Common - pyruvate formate lyase family activating protein SYN_03236 50 COG1313 PflX, Uncharacterized Fe-S protein PflX, homolog of pyruvate formate lyase activating proteins General function prediction only 85857913 Common - response regulator receiver domain SYN_00173 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 85859498 Common - hypothetical membrane protein SYN_01840 4 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 85858825 Common - uncharacterized BCR, YitT family protein SYN_01478 46 COG1284 COG1284, Uncharacterized conserved protein Function unknown 85858842 Nonpathogen - hypothetical cytosolic protein SYN_00401 1 COG1683 COG1683, Uncharacterized conserved protein Function unknown 85858435 Nonpathogen - hypothetical cytosolic protein SYN_02255 1 None None None 85859598 Common - hypothetical cytosolic protein SYN_02018 58 COG0011 COG0011, Uncharacterized conserved protein Function unknown 85859938 Common - thioredoxin peroxidase SYN_03680 46 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 85860712 Nonpathogen - hypothetical cytosolic protein SYN_02410 1 None None None 85858068 Common - response regulator with a HTH DNA-binding domain SYN_02588 220 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 85860721 Nonpathogen - hypothetical membrane protein SYN_02401 1 None None None 85858946 Common - signal transduction histidine kinase SYN_01364 223 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 85858109 Nonpathogen - hypothetical cytosolic protein SYN_01268 1 None None None 85859887 Common - hydrolase of the metallo-beta-lactamase superfamily SYN_00500 14 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 85859353 Nonpathogen - hypothetical protein SYN_03140 4 None None None 85859494 Nonpathogen - hypothetical cytosolic protein SYN_01835 1 None None None 85860702 Common - ferredoxin SYN_02420 45 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 85859946 Nonpathogen - hypothetical cytosolic protein SYN_00686 1 None None None 85860554 Nonpathogen - hypothetical cytosolic protein SYN_00301 3 None None None 85859281 Nonpathogen - hypothetical membrane protein SYN_02164 5 COG3350 COG3350, Uncharacterized conserved protein Function unknown 85858227 Common - fatty acid-CoA ligase SYN_01145 221 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 85860139 Common - tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase SYN_00798 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 85860951 Nonpathogen - hypothetical cytosolic protein SYN_03846 1 None None None 85858654 Common - iron-sulfur cluster-binding protein SYN_02901 44 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 85858806 Common - marC family integral membrane protein SYN_01458 153 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 85858009 Nonpathogen - hypothetical cytosolic protein SYN_03241 1 None None None 85858996 Common - hypothetical membrane protein SYN_03187 3 None None None 85860743 Nonpathogen - hypothetical cytosolic protein SYN_00377 1 None None None 85860171 Common - tRNA (Guanine-N(1)-)-methyltransferase SYN_00768 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 85860130 Common - hypothetical cytosolic protein SYN_00807 4 COG4274 COG4274, Uncharacterized conserved protein Function unknown 85860643 Nonpathogen - hypothetical cytosolic protein SYN_01081 1 None None None 85858711 Common - 2-oxoacid ferredoxin oxidoreductase, beta subunit SYN_03163 109 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 85858043 Common - adenosylmethionine-8-amino-7-oxononanoate aminotransferase SYN_02563 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 85860463 Common - alpha-L-glycero-D-manno-heptose alpha-1,3-glucosyltransferase SYN_02662 50 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 85858744 Nonpathogen - hypothetical cytosolic protein SYN_03164 6 None None None 85860370 Common - transcriptional regulator with sigma 54 interaction domain SYN_01191 177 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 85860580 Common - hypothetical cytosolic protein SYN_02469 9 None None None 85858203 Nonpathogen - hypothetical cytosolic protein SYN_00520 1 None None None 85858247 Nonpathogen - hypothetical cytosolic protein SYN_03329 1 None None None 85858934 Common - hypothetical cytosolic protein SYN_01375 76 COG3189 COG3189, Uncharacterized conserved protein Function unknown 85858500 Common rplT 50S ribosomal protein L20 SYN_01720 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 85859742 Common - general secretion pathway protein E SYN_01404 204 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 85858714 Common - L-lysine 2,3-aminomutase SYN_00182 127 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 85857862 Common - von Willebrand factor type A like domain SYN_02036 33 COG2425 COG2425, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 85859796 Common - fibronectin type III domain-containing protein SYN_02894 27 COG3401 COG3401, Fibronectin type 3 domain-containing protein General function prediction only 85858865 Common - transposase SYN_01325 84 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 85860295 Common - fosmidomycin resistance protein SYN_01218 85 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 85860087 Common - nickel-cobalt-cadmium resistance protein SYN_01562 37 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 85859811 Common - carD-like transcriptional regulator SYN_00997 84 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 85857846 Common - chromosomal replication initiator protein SYN_02051 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 85860573 Common - hypothetical cytosolic protein SYN_03793 3 None None None 85860900 Common - amidophosphoribosyltransferase SYN_01624 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 85858058 Common - hypothetical cytosolic protein SYN_02577 97 COG0432 COG0432, Uncharacterized conserved protein Function unknown 85860388 Common - radical SAM superfamily protein SYN_01173 49 COG0731 COG0731, Fe-S oxidoreductases Energy production and conversion 85860503 Common - xaa-pro dipeptidase SYN_01769 249 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 85860273 Nonpathogen - hypothetical cytosolic protein SYN_02513 1 None None None 85860020 Nonpathogen - hypothetical cytosolic protein SYN_00753 1 None None None 85860629 Common - transporter SYN_01068 33 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 85858894 Nonpathogen - hypothetical cytosolic protein SYN_03177 1 None None None 85860182 Common - hypothetical membrane protein SYN_01760 8 COG4967 PilV, Tfp pilus assembly protein PilV Cell motility and secretion / Intracellular trafficking and secretion 85859318 Common - uvrD/rep helicase SYN_02537 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 85859470 Common - hypothetical protein SYN_00764 4 None None None 85857903 Common - glycosyltransferase SYN_00036 218 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 85860518 Common - phosphoesterase, DHH family protein SYN_01784 78 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 85859588 Common - CrtK protein SYN_00101 65 COG3476 COG3476, Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) Signal transduction mechanisms 85860636 Common - tetratricopeptide repeat family protein SYN_01075 25 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 85859015 Nonpathogen - hypothetical cytosolic protein SYN_03191 1 None None None 85859805 Common - methylmalonyl-CoA decarboxylase, alpha-subunit SYN_01398 214 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 85858641 Nonpathogen - hypothetical cytosolic protein SYN_01753 1 None None None 85859113 Common - poly A polymerase SYN_01518 214 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 85858193 Common - hypothetical cytosolic protein SYN_02034 13 None None None 85858558 Common - hypothetical cytosolic protein SYN_02451 5 None None None 85859179 Common - flagellar biosynthetic protein SYN_03207 9 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 85858648 Common - flavodoxin SYN_03151 20 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 85859227 Common - integrase core domain protein SYN_01387 20 None None None 85858536 Common - methyl-accepting chemotaxis protein SYN_00432 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 85858332 Common - acetyl-CoA hydrolase/transferase SYN_02360 100 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 85859923 Nonpathogen - hypothetical cytosolic protein SYN_03671 1 None None None 85858563 Common - glycerol-3-phosphate dehydrogenase SYN_02446 129 COG0579 COG0579, Predicted dehydrogenase General function prediction only 85859377 Common - DNA-binding protein, ComEA family SYN_02782 71 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 85860612 Common - iron(III) dicitrate-biding protein SYN_01051 62 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 85859752 Common - hydrolase SYN_01415 21 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 85860594 Common - hydroxyacylglutathione hydrolase SYN_01287 204 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 85857892 Common - hlyD family secretion protein SYN_00025 163 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 85858726 Common - periplasmic protease SYN_00194 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 85858988 Nonpathogen - LSU ribosomal protein L34 SYN_01011 1 None None None 85859225 Nonpathogen - hypothetical cytosolic protein SYN_01389 1 None None None 85860939 Common - hypothetical membrane protein SYN_00210 67 COG1268 BioY, Uncharacterized conserved protein General function prediction only 85857983 Common - heterodisulfide reductase, subunit A and related polyferredoxins SYN_00626 49 COG1148 HdrA, Heterodisulfide reductase, subunit A and related polyferredoxins Energy production and conversion 85860160 Common - tyrosine-protein kinase SYN_00779 137 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 85859308 Nonpathogen - hypothetical cytosolic protein SYN_02547 1 None None None 85859160 Common - alpha-amylase SYN_02854 120 COG1449 COG1449, Alpha-amylase/alpha-mannosidase Carbohydrate transport and metabolism 85859423 Common - exodeoxyribonuclease V alpha chain SYN_01037 144 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 85860914 Nonpathogen - hypothetical cytosolic protein SYN_01608 1 None None None 85860038 Common - phosphorylase family 2 protein SYN_00047 164 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 85858750 Nonpathogen - hypothetical cytosolic protein SYN_02749 4 None None None 85860101 Common - hypothetical membrane protein SYN_00927 110 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 85860173 Common - RNA binding protein SYN_00766 69 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 85859025 Common - methyl-accepting chemotaxis protein SYN_00977 136 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 85860178 Nonpathogen - hypothetical cytosolic protein SYN_03024 2 None None None 85858319 Nonpathogen - hypothetical protein SYN_03861 32 COG1148 HdrA, Heterodisulfide reductase, subunit A and related polyferredoxins Energy production and conversion 85859972 Nonpathogen - hypothetical membrane protein SYN_03103 1 None None None 85860132 Common - Selenoprotein A SYN_03718 6 None None None 85860248 Nonpathogen - hypothetical cytosolic protein SYN_02489 1 None None None 85858446 Nonpathogen - hypothetical cytosolic protein SYN_02244 1 None None None 85860401 Common - hypothetical cytosolic protein SYN_03124 232 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 85858759 Nonpathogen - hypothetical cytosolic protein SYN_03165 1 None None None 85858848 Nonpathogen - hypothetical membrane protein SYN_02928 1 None None None 85858495 Common - putative periplasmic protein SYN_03044 17 COG4254 COG4254, Uncharacterized protein conserved in bacteria Function unknown 85859155 Common - membrane-bound lytic murein transglycosylase SYN_02860 93 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 85859194 Common - flagellar biosynthetic protein SYN_02821 119 COG2257 COG2257, Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB Function unknown 85858359 Common - hypothetical cytosolic protein SYN_02332 7 None None None 85860242 Common - bon domain protein SYN_01579 18 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 85859247 Nonpathogen - hypothetical cytosolic protein SYN_03545 1 None None None 85858344 Common - hypothetical membrane protein SYN_02348 4 None None None 85860767 Common - hypothetical membrane protein SYN_00354 45 None None None 85858981 Common - deacetylase family protrein SYN_01017 135 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 85858173 Common - DNA-directed RNA polymerase subunit alpha SYN_01601 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 85859667 Common - indole-3-glycerol phosphate synthase SYN_01944 218 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 85859683 Common - muramoyltetrapeptide carboxypeptidase SYN_01084 79 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 85860582 Nonpathogen - hypothetical cytosolic protein SYN_02467 2 None None None 85859548 Nonpathogen - hypothetical cytosolic protein SYN_03585 1 None None None 85859858 Common - hypothetical cytosolic protein SYN_00473 137 COG0432 COG0432, Uncharacterized conserved protein Function unknown 85858112 Nonpathogen - hypothetical cytosolic protein SYN_03253 1 None None None 85858090 Common - pyridine nucleotide oxidoreductase SYN_01441 246 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 85859991 Nonpathogen - hypothetical cytosolic protein SYN_00727 1 None None None 85860321 Nonpathogen - hypothetical protein SYN_01245 1 None None None 85859527 Common - conjugal DNA transfer protein SYN_01869 26 None None None 85859898 Nonpathogen - hypothetical membrane protein SYN_00510 1 None None None 85858828 Common - D-alanine--D-alanine ligase SYN_01483 213 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 85859786 Common - biotin operon repressor / biotin--[acetyl-CoA-carboxylase] synthetase SYN_02884 226 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 85859674 Nonpathogen - hypothetical cytosolic protein SYN_02765 1 None None None 85860340 Common - hypothetical cytosolic protein SYN_00862 27 COG3945 COG3945, Uncharacterized conserved protein Function unknown 85859061 Common - serine kinase of the HPr protein, regulates carbohydrate metabolism SYN_00942 63 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 85860423 Common - orotate phosphoribosyltransferase SYN_02702 214 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 85859530 Common - type IV secretory protease SYN_01872 5 COG4959 TraF, Type IV secretory pathway, protease TraF Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 85857977 Nonpathogen - sugar phosphate isomerase/epimerase SYN_00620 5 None None None 85859564 Common - small heat shock protein SYN_01907 139 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 85860341 Nonpathogen - hypothetical cytosolic protein SYN_03757 1 None None None 85860980 Nonpathogen - hypothetical cytosolic protein SYN_02084 1 None None None 85859914 Nonpathogen - hypothetical cytosolic protein SYN_03091 1 None None None 85860792 Common - acetyltransferase, GNAT family SYN_00327 29 COG0456 RimI, Acetyltransferases General function prediction only 85859392 Common - peptidase, M16 family SYN_03142 172 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 85858403 Common - mu-like prophage DNA circulation protein SYN_02289 8 COG4228 COG4228, Mu-like prophage DNA circulation protein General function prediction only 85859368 Common - 3-methyl-2-oxobutanoate hydroxymethyltransferase SYN_02773 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 85859537 Nonpathogen - hypothetical membrane protein SYN_01880 1 None None None 85858099 Common - hypothetical kinase SYN_03250 222 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 85860157 Common - periplasmic protein involved in polysaccharide export SYN_00782 119 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 85860464 Common - NAD dependent epimerase/dehydratase family SYN_02661 231 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 85859171 Nonpathogen - hypothetical cytosolic protein SYN_02843 1 None None None 85860820 Common - ketol-acid reductoisomerase / 2-dehydropantoate 2-reductase SYN_01709 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 85858513 Common - enolase SYN_01733 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 85860025 Common - DNA primase SYN_00758 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 85859950 Common - hypothetical membrane protein SYN_00689 40 COG3647 COG3647, Predicted membrane protein Function unknown 85857911 Common - metal-dependent hydrolase SYN_00175 46 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 85860238 Nonpathogen - hypothetical protein SYN_01583 5 None None None 85860680 Common - type I secretion outer membrane protein SYN_00239 147 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 85859762 Common - hypothetical cytosolic protein SYN_01308 75 COG1469 COG1469, Uncharacterized conserved protein Function unknown 85860294 Common - hypothetical membrane protein SYN_01217 59 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 85859545 Nonpathogen - hypothetical cytosolic protein SYN_03052 1 None None None 85860913 Common - glutathione-regulated potassium-efflux system protein SYN_01610 133 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 85860675 Common - cytochrome c-type protein SYN_02615 28 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 85860735 Nonpathogen - hypothetical membrane protein SYN_02387 1 None None None 85858796 Common - hydroxyacylglutathione hydrolase W SYN_02709 222 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 85860454 Common - pleiotrophic regulatory protein SYN_02671 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 85860313 Nonpathogen - hypothetical cytosolic protein SYN_01237 1 None None None 85859554 Common - glutamine amidotransferases class-II SYN_01896 29 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 85860209 Common - hypE-like hydrogenase expression/formation protein SYN_00601 128 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 85858138 Common - DNA-directed RNA polymerase beta chain SYN_00064 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 85858503 Common - phenylalanyl-tRNA synthetase beta chain SYN_01723 249 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 85858134 Common - LSU ribosomal protein L11 SYN_00069 247 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 85860252 Common - rubredoxin SYN_02492 124 COG1773 COG1773, Rubredoxin Energy production and conversion 85859798 Nonpathogen - hypothetical cytosolic protein SYN_01392 1 None None None 85859444 Common - aspartate aminotransferase SYN_00908 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 85859513 Common - predicted transcriptional regulator, DeoR family SYN_01855 45 COG2378 COG2378, Predicted transcriptional regulator Transcription 85857972 Common - Ni,Fe-hydrogenase maturation factor SYN_02223 34 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 85858808 Common - export ABC transporter ATP-binding protein SYN_01460 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 85858607 Common pgi glucose-6-phosphate isomerase SYN_02950 178 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 85858429 Common - DNA polymerase I SYN_02261 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 85858667 Nonpathogen - hypothetical cytosolic protein SYN_02915 1 None None None 85859051 Common - integrase/recombinase SYN_00952 230 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 85858483 Common - Fe-S oxidoreductase SYN_00538 50 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 85857883 Common - hypothetical cytosolic protein SYN_00016 12 None None None 85859451 Common - xanthosine triphosphate pyrophosphatase SYN_00901 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 85859209 Common - flagellin-specific chaperone SYN_02806 78 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 85860497 Common - ribulose-phosphate 3-epimerase SYN_01763 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 85858686 Common - 4-alpha-glucanotransferase SYN_00881 219 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 85858838 Common - hypothetical cytosolic protein SYN_00405 73 COG2331 COG2331, Uncharacterized protein conserved in bacteria Function unknown 85858831 Common - D-alanine--D-alanine ligase SYN_00412 213 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 85859108 Nonpathogen - hypothetical cytosolic protein SYN_03524 1 None None None 85858732 Common - smr domain protein SYN_02482 89 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 85859076 Common - fumarate reductase/succinate dehydrogenase flavoprotein C-terminal domain SYN_00424 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 85860520 Common - hypothetical cytosolic protein SYN_01786 35 COG1550 COG1550, Uncharacterized protein conserved in bacteria Function unknown 85859331 Common - phosphotyrosine protein phosphatase SYN_00054 136 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 85860894 Common - glutamate synthase (NADPH) SYN_01630 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 85857941 Common - FfdnI cytochrome b subunit of formate dehydrogenase SYN_00144 18 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 85858659 Nonpathogen - hypothetical cytosolic protein SYN_02906 1 None None None 85860367 Nonpathogen - hypothetical cytosolic protein SYN_01194 1 None None None 85860840 Common - hypothetical cytosolic protein SYN_01687 9 None None None 85859202 Nonpathogen - hypothetical cytosolic protein SYN_02813 2 None None None 85860127 Nonpathogen - hypothetical cytosolic protein SYN_00810 2 None None None 85858592 Common - ATP synthase C chain SYN_02965 44 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 85859043 Common - chemotaxis protein SYN_00960 119 COG1360 MotB, Flagellar motor protein Cell motility and secretion 85859665 Common - tryptophan synthase subunit beta SYN_01942 227 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 85858166 Common - LSU ribosomal protein L15P SYN_01594 214 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 85860335 Common - methyltransferase SYN_01259 63 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 85858969 Nonpathogen - hypothetical cytosolic protein SYN_03508 1 None None None 85859087 Common - hypothetical protein SYN_03192 29 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 85858689 Nonpathogen - hypothetical membrane protein SYN_00878 8 None None None 85858124 Common - 23S rRNA Gm2251 methyltransferase SYN_01282 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 85859214 Common - response regulator with GAF and HD domains SYN_02801 225 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 85857948 Common - lysine efflux protein SYN_02198 42 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 85858468 Common - rod shape-determining protein SYN_00553 155 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 85859736 Nonpathogen - hypothetical cytosolic protein SYN_01922 2 None None None 85858254 Nonpathogen - hypothetical cytosolic protein SYN_03330 1 None None None 85858782 Nonpathogen - hypothetical membrane protein SYN_02720 2 None None None 85859125 Common - ATPase SYN_01506 57 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 85860545 Nonpathogen - hypothetical cytosolic protein SYN_03785 2 COG2006 COG2006, Uncharacterized conserved protein Function unknown 85860065 Nonpathogen - hypothetical cytosolic protein SYN_01541 1 None None None 85860853 Common - cyclopropane-fatty-acyl-phospholipid synthase SYN_01675 133 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 85858304 Common - hypothetical cytosolic protein SYN_02613 39 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 85859647 Common - fructose-1,6-bisphosphatase SYN_01924 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 85858368 Nonpathogen - hypothetical cytosolic protein SYN_02323 1 None None None 85860987 Common - transcriptional regulator SYN_02078 101 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 85860624 Nonpathogen - hypothetical membrane protein SYN_01062 1 None None None 85857854 Common - hypothetical membrane protein SYN_02043 38 COG0551 TopA, Zn-finger domain associated with topoisomerase type I DNA replication, recombination, and repair 85858801 Common - cell division inhibitor SYN_02704 95 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 85859342 Common - lipoprotein signal peptidase SYN_01453 188 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 85858062 Nonpathogen - hypothetical cytosolic protein SYN_03294 2 None None None 85858524 Common - UDP-N-acetylmuramoylalanine--D-glutamate ligase SYN_01744 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 85858072 Common - ABC-type transporter cobalamide binding protein SYN_01423 178 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 85858309 Common - hypothetical cytosolic protein SYN_00249 3 None None None 85860750 Common - activator of D-2-hydroxyacyl-CoA dehydratase SYN_00371 65 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 85859013 Common - hypothetical cytosolic protein SYN_00119 2 None None None 85859997 Nonpathogen - hypothetical cytosolic protein SYN_03106 1 None None None 85859776 Common - dephospho-CoA kinase SYN_02876 209 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 85858818 Common - flagellar motor switch protein SYN_01471 124 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 85858014 Nonpathogen - hypothetical cytosolic protein SYN_02384 1 None None None 85858158 Common - LSU ribosomal protein L24P SYN_03313 213 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 85858033 Common - 3-oxoacyl-[acyl-carrier-protein] synthase SYN_02365 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 85858233 Common - hypothetical cytosolic protein SYN_01139 5 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 85859843 Nonpathogen - hypothetical cytosolic protein SYN_00460 1 None None None 85859079 Common - dimethyladenosine transferase SYN_00421 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 85857897 Common - molecular chaperone SYN_00030 135 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 85858461 Nonpathogen - hypothetical cytosolic protein SYN_03401 1 None None None 85860444 Common - glycosyltransferase SYN_02681 63 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 85859197 Common - flagellar basal body P-ring biosynthesis protein SYN_02818 13 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 85859990 Common - uspA family domain-containing protein SYN_00726 16 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 85858959 Common - sensory transduction protein with PAS domain SYN_00566 103 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 85860169 Common rplS 50S ribosomal protein L19 SYN_00770 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 85859458 Nonpathogen - hypothetical protein SYN_00895 25 COG2122 COG2122, Uncharacterized conserved protein Function unknown 85859691 Common - potassium uptake protein SYN_01091 142 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 85858349 Nonpathogen - hypothetical cytosolic protein SYN_02343 2 None None None 85860287 Common - butyrate kinase SYN_01210 143 COG3426 COG3426, Butyrate kinase Energy production and conversion 85859096 Common - integration host factor beta-subunit SYN_03200 204 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 85860475 Common - CDP-4-dehydro-6-deoxy-D-glucose 3-epimerase SYN_02650 161 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 85857847 Common - DNA polymerase III, beta chain SYN_02050 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 85858960 Common - transposase SYN_00567 69 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 85859032 Common - methyl-accepting chemotaxis protein SYN_00971 107 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 85860541 Common - glyceraldehyde 3-phosphate dehydrogenase SYN_01810 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 85859366 Nonpathogen - hypothetical cytosolic protein SYN_01970 6 None None None 85860329 Common - cysteine synthase SYN_01253 217 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 85859558 Common - GTP pyrophosphokinase / guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase SYN_01901 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 85858064 Common - superfamily II DNA helicase SYN_02584 236 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 85860658 Common - membrane-bound lytic murein transglycosylase B SYN_02632 102 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 85858383 Nonpathogen - hypothetical cytosolic protein SYN_03376 1 None None None 85859270 Common hslU ATP-dependent protease ATP-binding subunit SYN_02153 211 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 85859137 Common - flp pilus assembly protein family SYN_01494 22 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 85859649 Common - tellurium resistance protein SYN_01926 104 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 85858362 Nonpathogen - hypothetical cytosolic protein SYN_03364 1 None None None 85859283 Common - hypothetical cytosolic protein SYN_03220 59 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 85860940 Common - ABC-type cobalt transport system, ATPase component SYN_00209 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 85858522 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase SYN_01742 211 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 85859956 Common - phage integrase family protein SYN_00695 196 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 85860596 Nonpathogen - hypothetical cytosolic protein SYN_01288 1 None None None 85860844 Common - imidazole glycerol phosphate synthase, glutamine amidotransferase subunit SYN_01683 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 85859749 Common - radical SAM family enzyme SYN_01411 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 85860833 Common - 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase SYN_01695 124 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 85857889 Common - ABC transporter permease protein SYN_00022 40 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 85859440 Common - CDP-diacylglycerol--serine O-phosphatidyltransferase SYN_00912 153 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 85858851 Nonpathogen - hypothetical membrane protein SYN_03067 1 None None None 85858870 Common - hypothetical cytosolic protein SYN_01320 31 COG3089 COG3089, Uncharacterized protein conserved in bacteria Function unknown 85860948 Common - hypothetical membrane protein SYN_03080 2 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 85859382 Common - ATP-dependent protease La SYN_02787 211 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 85859831 Common - hypothetical membrane protein SYN_00447 32 COG2839 COG2839, Uncharacterized protein conserved in bacteria Function unknown 85858530 Common - cell division protein SYN_03127 180 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 85860570 Common - triosephosphate isomerase SYN_03790 215 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 85860827 Common - signal transduction histidine kinase SYN_01701 223 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 85860867 Nonpathogen - hypothetical protein SYN_03073 3 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 161347547 Common - ribonucleotide-diphosphate reductase subunit alpha SYN_01226 224 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 85858222 Common - 3-oxoacyl-[acyl-carrier-protein] synthase III SYN_01150 75 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 85858340 Nonpathogen - hypothetical cytosolic protein SYN_02352 1 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 85858697 Common - pili retraction protein SYN_00126 210 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 85859936 Nonpathogen - hypothetical cytosolic protein SYN_03095 1 None None None 85858023 Nonpathogen - hypothetical membrane protein SYN_02375 11 None None None 85858877 Nonpathogen - hypothetical cytosolic protein SYN_03481 1 None None None 85859201 Common - negative regulator of flagellin synthesis SYN_02814 7 None None None 85859399 Nonpathogen - hypothetical membrane protein SYN_02181 1 None None None 85858298 Common - acetyl-CoA synthetase / acetyltransferase (GNAT) family protein SYN_02607 159 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 85859417 Nonpathogen - hypothetical cytosolic protein SYN_03144 1 None None None 85860409 Common - multimeric flavodoxin SYN_00084 119 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 85859651 Nonpathogen - hypothetical cytosolic protein SYN_01928 1 None None None 85858420 Common - hypothetical cytosolic protein SYN_02271 62 COG3272 COG3272, Uncharacterized conserved protein Function unknown 85860435 Common - wbfB protein SYN_02690 23 None None None 85860936 Nonpathogen - hypothetical cytosolic protein SYN_00213 1 None None None 85858571 Common - phosphoribosylamine--glycine ligase SYN_02439 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 85858679 Common - ATPase related to magnesium chelatase subunit SYN_03153 201 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 85860149 Common - ABC-type branched-chain amino acid transport systems, periplasmic component SYN_00789 155 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 85860709 Nonpathogen - hypothetical cytosolic protein SYN_02413 1 None None None 85858277 Common - undecaprenyl-phosphate alpha-N-acetylglucosaminephosphotransferase SYN_01096 164 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 85860133 Common - glycine reductase complex protein C large subunit SYN_00804 8 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 85858970 Common - bacterial regulatory protein, LuxR family SYN_01028 33 COG4566 TtrR, Response regulator Signal transduction mechanisms 85859404 Common - coproporphyrinogen III oxidase SYN_02186 209 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 85860808 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B SYN_00309 213 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 85860207 Common - Ni2+ insertion GTPase SYN_00599 146 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 85860266 Common - outer membrane protein SYN_02507 7 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 85859574 Common - tRNA s2C32 biosynthesis protein SYN_02190 143 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 85858858 Nonpathogen - hypothetical cytosolic protein SYN_01333 1 None None None 85858430 Common - D-alanyl-D-alanine serine-type carboxypeptidase SYN_02260 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 85860510 Common - pili assembly protein SYN_01776 85 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 85859875 Nonpathogen - hypothetical cytosolic protein SYN_00489 1 None None None 85858456 Common - hypothetical cytosolic protein SYN_02235 17 COG3598 RepA, RecA-family ATPase DNA replication, recombination, and repair 85859118 Common - ATPase SYN_01513 34 COG1672 COG1672, Predicted ATPase (AAA+ superfamily) General function prediction only 85860177 Common - arginyl-tRNA synthetase SYN_00994 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 85859635 Common - nifU-like domain protein SYN_02452 137 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 85859847 Nonpathogen - hypothetical cytosolic protein SYN_00462 1 None None None 85860411 Common - plasmid maintenance system antidote protein SYN_00086 10 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 85858350 Common - cardiolipin synthetase SYN_02342 148 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 85858312 Nonpathogen - hypothetical cytosolic protein SYN_00252 1 None None None 85860446 Nonpathogen - hypothetical membrane protein SYN_02679 1 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 85858597 Common - UDP-N-acetylglucosamine pyrophosphorylase SYN_02960 26 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 85860382 Common - dinitrogenase iron-molybdenum cofactor protein SYN_01179 30 COG1433 COG1433, Uncharacterized conserved protein Function unknown 85860140 Common - tRNA 2-methylthioadenosine synthase -like protein SYN_00797 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 85859623 Common - ABC transporter ATP-binding protein SYN_01994 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 85858811 Common - tetratricopeptide repeat domain protein SYN_01464 17 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 85860669 Common - menaquinone biosynthesis related protein, hydrolase SYN_02621 146 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 85860504 Nonpathogen - hypothetical cytosolic protein SYN_01770 7 None None None 85858770 Nonpathogen - hypothetical cytosolic protein SYN_03462 1 None None None 85859836 Nonpathogen - hypothetical membrane protein SYN_00452 1 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 85859477 Common - hypothetical cytosolic protein SYN_01817 28 COG4913 COG4913, Uncharacterized protein conserved in bacteria Function unknown 85859965 Common - hypothetical cytosolic protein SYN_00703 2 None None None 85857868 Common - hypothetical membrane protein SYN_00003 31 COG4095 COG4095, Uncharacterized conserved protein Function unknown 85859048 Common - ABC-type Mn/Zn transport system ATPase component SYN_00955 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 85859890 Nonpathogen - hypothetical cytosolic protein SYN_00503 5 None None None 85859269 Common - ATP-dependent protease peptidase subunit SYN_02152 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 85858611 Common - type I secretion outer membrane protein SYN_02946 139 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 85859449 Common - N-acetylmuramoyl-L-alanine amidase SYN_00903 181 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 85859325 Common - single-stranded DNA-specific exonuclease SYN_02529 194 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 85858215 Common - small heat shock protein SYN_01157 103 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 85858569 Common - phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase SYN_02440 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 85859162 Common - ATP-dependent helicase SYN_02852 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 85860429 Nonpathogen - hypothetical membrane protein SYN_03121 1 None None None 85859662 Common - 3-dehydroquinate synthase SYN_01939 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 85860806 Common - predicted phosphatases SYN_00311 56 COG0546 Gph, Predicted phosphatases General function prediction only 85859256 Common - N-terminal domain of molybdenum-binding protein SYN_00268 75 COG3585 MopI, Molybdopterin-binding protein Coenzyme metabolism 85857908 Common - superfamily II DNA and RNA helicases SYN_00178 238 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 85858721 Common - peptidoglycan-associated lipopeptide SYN_00189 154 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 85859509 Nonpathogen - hypothetical cytosolic protein SYN_01851 4 None None None 85859740 Common - protein translation Elongation Factor G (EF-G) SYN_01918 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 85859700 Common - glycerol-3-phosphate dehydrogenase (NAD(P)+) SYN_01987 210 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 85860210 Common - formate dehydrogenase major subunit SYN_00602 176 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 85859375 Common - ATP/GTP hydrolase SYN_02780 204 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 85857951 Common - pyruvate dehydrogenase (ferredoxin/flavodoxin-dependent) SYN_02201 124 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 85860536 Common - hypothetical cytosolic protein SYN_01806 7 None None None 85859091 Common - zinc metalloprotease SYN_03195 130 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 85860764 Common - predicted alternative thymidylate synthase SYN_00357 42 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 85858976 Common - erfK/ybiS/ycfS/ynhG family protein SYN_01021 67 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 85858433 Common - 1,4-alpha-glucan branching enzyme SYN_02257 150 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 85859815 Nonpathogen - hypothetical cytosolic protein SYN_01001 1 None None None 85858703 Common - o-antigen polymerase SYN_00132 9 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 85858280 Common - chain length determinant protein, Wzz-like protein SYN_01204 85 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 85860835 Common - acyl carrier protein SYN_01693 47 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 85858419 Common - uroporphyrin-III C-methyltransferase / uroporphyrinogen-III synthase SYN_02272 210 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 85860927 Common - glutamate racemase SYN_00222 191 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 85860811 Nonpathogen - sec-independent protein translocase protein SYN_00306 9 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 85858408 Common - phage protein SYN_02284 20 COG3778 COG3778, Uncharacterized protein conserved in bacteria Function unknown 85860258 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit beta SYN_02499 109 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 85857882 Common - transcriptional regulator with HTH domain SYN_00015 20 COG2944 COG2944, Predicted transcriptional regulator Transcription 85858103 Common - ABC-type transport system involved in resistance to organic solvents, permease component SYN_01262 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 85859355 Common - hypothetical cytosolic protein exonuclease SYN_00384 19 COG3359 COG3359, Predicted exonuclease DNA replication, recombination, and repair 85860911 Nonpathogen - hypothetical cytosolic protein SYN_01612 1 None None None 85860240 Common - endonuclease/exonuclease/phosphatase family protein SYN_01581 26 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 85860682 Common - export ABC transporter ATP-binding protein SYN_00241 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 85859274 Common - argininosuccinate synthase SYN_02157 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 85860885 Common - tungsten-containing aldehyde ferredoxin oxidoreductase SYN_01640 57 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 85859888 Common - hydrolase of the metallo-beta-lactamase superfamily SYN_00501 11 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 85859496 Nonpathogen - hypothetical cytosolic protein SYN_01838 1 None None None 85860953 Common - superfamily II DNA and RNA helicases SYN_01298 238 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 85860641 Common - ggdef family protein / response regulator receiver domain SYN_01079 223 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 85859596 Common - nitroreductase family protein SYN_02020 73 COG0778 NfnB, Nitroreductase Energy production and conversion 85858716 Common - truncated lysyl-tRNA synthetase SYN_00184 240 COG2269 COG2269, Truncated, possibly inactive, lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 85858656 Common - sugar-phosphate nucleotidyltransferase SYN_02903 199 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 85858201 Common - NAD-dependent malic enzyme SYN_00517 194 COG0281 SfcA, Malic enzyme Energy production and conversion 85859719 Common - hypothetical membrane protein SYN_03005 127 COG2860 COG2860, Predicted membrane protein Function unknown 85857970 Common - nickel-dependent hydrogenase, small chain SYN_02221 47 COG1941 FrhG, Coenzyme F420-reducing hydrogenase, gamma subunit Energy production and conversion 85857860 Nonpathogen - hypothetical membrane protein SYN_02038 4 COG5373 COG5373, Predicted membrane protein Function unknown 85859808 Common - 2-c-methyl-d-erythritol 2,4-cyclodiphosphate synthase SYN_01400 189 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 85860216 Common - oligopeptide-binding protein SYN_00608 215 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 85858479 Common - transcription elongation factor SYN_00542 201 COG0782 GreA, Transcription elongation factor Transcription 85859500 Nonpathogen - hypothetical cytosolic protein SYN_01842 3 None None None 85860078 Common - hypothetical membrane protein SYN_01553 5 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 85859005 Nonpathogen - hypothetical cytosolic protein SYN_00114 1 None None None 85857895 Common - co-chaperonin SYN_00028 215 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 85860040 Common - thioredoxin SYN_00045 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 85860608 Common - iron(III) dicitrate transport protein SYN_01048 123 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 85860664 Common - lipopolysaccharide N-acetylglucosaminyltransferase SYN_02626 108 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 85858144 Common - elongation factor Tu SYN_00983 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 85860222 Nonpathogen - hypothetical cytosolic protein SYN_03021 1 None None None 85859616 Common - gamma-glutamyl phosphate reductase SYN_02002 195 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 85858644 Nonpathogen - hypothetical cytosolic protein SYN_01751 1 None None None 85859456 Common - Inosine-5'-monophosphate dehydrogenase SYN_00897 242 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 85858177 Common - folylpolyglutamate synthase / dihydrofolate synthase SYN_01606 217 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 85858966 Nonpathogen - hypothetical membrane protein SYN_03182 1 None None None 85857991 Common - formate dehydrogenase major subunit SYN_00634 169 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 85860530 Common - hypothetical protein SYN_01799 182 COG1496 COG1496, Uncharacterized conserved protein Function unknown 85857935 Common - heme export protein apocytochrome heme-lyase SYN_00150 190 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 85858196 Nonpathogen - hypothetical membrane protein SYN_00513 2 None None None 85859712 Common mscL large-conductance mechanosensitive channel SYN_01974 143 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 85860480 Nonpathogen - hypothetical cytosolic protein SYN_03771 1 None None None 85860190 Common - transcription antitermination protein SYN_00580 203 COG0250 NusG, Transcription antiterminator Transcription 85858690 Common - glycogen synthase SYN_00877 79 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 85858762 Common - hypothetical cytosolic protein SYN_02738 8 None None None 85860958 Nonpathogen - hypothetical membrane protein SYN_03850 2 None None None 85858291 Common - superfamily I DNA and RNA helicase SYN_02599 223 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 85859426 Common - polysaccharide deacetylase SYN_01034 14 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 85859236 Common - aldehyde dehydrogenase (ferredoxin) SYN_01377 56 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 85860603 Common - transposase SYN_01043 32 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 85859905 Nonpathogen - hypothetical cytosolic protein SYN_00651 1 None None None 85860651 Common - mannosyl-3-phosphoglycerate phosphatase SYN_00870 29 COG3769 COG3769, Predicted hydrolase (HAD superfamily) General function prediction only 85857915 Common - predicted signal transduction protein SYN_00171 61 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 85860785 Nonpathogen - hypothetical cytosolic protein SYN_03823 5 COG0316 IscA, Uncharacterized conserved protein Function unknown 85858100 Nonpathogen - hypothetical membrane protein SYN_01450 1 None None None 85858253 Nonpathogen - hypothetical cytosolic protein SYN_01119 2 None None None 85860693 Nonpathogen - hypothetical membrane protein SYN_02429 14 COG3462 COG3462, Predicted membrane protein Function unknown 85860818 Common - acetolactate synthase large subunit SYN_01711 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 85859373 Common - dihydropteroate synthase SYN_02778 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 85860535 Common - ribonuclease Z SYN_01804 77 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 85859881 Common - type I restriction-modification system methylation subunit SYN_00494 160 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 85860153 Common - branched-chain amino acid transport ATP-binding protein SYN_00785 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 85859707 Common - anaerobic ribonucleoside-triphosphate reductase SYN_01979 100 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 85858327 Common - xanthine-guanine phosphoribosyltransferase SYN_03353 83 COG2236 COG2236, Predicted phosphoribosyltransferases General function prediction only 85858684 Nonpathogen - hypothetical cytosolic protein SYN_03450 1 None None None 85859910 Common - iron-sulfur flavoprotein SYN_00657 39 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 85860868 Common - ferredoxin SYN_01658 83 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 85860118 Common - glycosyltransferase involved in cell wall biogenesis SYN_00819 134 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 85860355 Nonpathogen - hypothetical cytosolic protein SYN_00849 1 None None None 85859055 Common - hypothetical membrane protein SYN_00948 5 COG3117 COG3117, Uncharacterized protein conserved in bacteria Function unknown 85858600 Common - hypothetical membrane protein SYN_02957 8 None None None 85860260 Common - succinyl-CoA synthetase beta chain SYN_02501 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 85860365 Common - acetolactate synthase small subunit SYN_01196 38 COG4747 COG4747, ACT domain-containing protein General function prediction only 85857919 Common - metallo-beta-lactamase protein SYN_00166 126 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 85859085 Common - permease SYN_00415 110 COG0795 COG0795, Predicted permeases General function prediction only 85859576 Common - HD-superfamily hydrolase SYN_02192 48 COG3481 COG3481, Predicted HD-superfamily hydrolase General function prediction only 85858846 Nonpathogen - hypothetical cytosolic protein SYN_00399 1 None None None 85861000 Common - export ABC transporter ATP-binding protein / export ABC transporter permease protein SYN_02065 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 85859041 Common - chemotaxis protein SYN_00962 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 85860920 Common - anti-sigma B factor antagonist SYN_00229 74 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 85859682 Common - 2-hydroxyacid dehydrogenase, D-isomer specific SYN_01083 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 85859610 Common - act domain-containing protein SYN_02007 32 COG2716 GcvR, Glycine cleavage system regulatory protein Amino acid transport and metabolism 85858448 Nonpathogen - hypothetical cytosolic protein SYN_02242 1 None None None 85858736 Common - excinuclease ABC subunit A SYN_02486 239 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 85860461 Common - alpha-1,2-fucosyltransferase SYN_02664 19 None None None 85858016 Common - glutamate dehydrogenase SYN_02382 169 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 85859734 Nonpathogen - hypothetical cytosolic protein SYN_03629 1 None None None 85860403 Common - hypothetical protein SYN_00077 29 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 85859295 Common - hypothetical cytosolic protein SYN_01573 7 None None None 85859484 Common - type III restriction-modification system restriction subunit SYN_01824 42 COG3587 COG3587, Restriction endonuclease Defense mechanisms 85859184 Common - flagellar biosynthesis protein SYN_02830 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 85858002 Common - plasmid maintenance system antidote protein SYN_00843 30 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 85858175 Nonpathogen - hypothetical cytosolic protein SYN_03317 1 None None None 85859063 Common - peptidoglycan-specific endopeptidase, M23 family SYN_00940 187 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 85859993 Common - L-aspartate oxidase SYN_00729 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 85858918 Common - iron-sulfur flavoprotein SYN_02131 48 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 85860466 Common - glycosyltransferase SYN_02659 122 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 85858168 Common - methionine aminopeptidase SYN_01596 248 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 85857946 Common - membrane protein SYN_03234 48 COG1584 COG1584, Predicted membrane protein Function unknown 85858110 Common - zinc-binding dehydrogenase SYN_01269 210 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 85860334 Common - quinolinate synthetase SYN_01258 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 85860695 Common - 2Fe-2S and 4Fe-4S iron-sulfur protein SYN_02427 182 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 85858983 Common - tRNA synthase SYN_01016 228 COG0486 ThdF, Predicted GTPase General function prediction only 85859543 Common - DNA transfer in the process of conjugation and F pilus assembly protein SYN_01886 33 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 85857928 Common - pyruvate:ferredoxin oxidoreductase gamma subunit SYN_00157 72 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 85857999 Nonpathogen - hypothetical membrane protein SYN_01957 2 None None None 85860794 Common - hypothetical cytosolic protein SYN_00324 8 COG1633 COG1633, Uncharacterized conserved protein Function unknown 85860653 Common - calcium-transporting ATPase SYN_00872 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 85860976 Common - thioredoxin SYN_02089 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 85859979 Nonpathogen - hypothetical cytosolic protein SYN_03105 1 None None None 85858406 Nonpathogen - phage protein gp46 SYN_02286 1 COG4381 COG4381, Mu-like prophage protein gp46 Function unknown 85857923 Common - DNA polymerase III subunit gamma/tau SYN_00163 248 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 85860965 Nonpathogen - hypothetical membrane protein SYN_02100 11 None None None 85859709 Common - hypothetical protein SYN_01977 34 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 85860673 Common - trk system potassium uptake protein SYN_02617 137 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 85860359 Nonpathogen - hypothetical cytosolic protein SYN_01202 1 None None None 85859466 Common - phosphoribosylglycinamide formyltransferase SYN_00888 223 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 85860477 Common - CDP-glucose 4,6-dehydratase SYN_02648 214 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 85858151 Common - LSU ribosomal protein L22P SYN_00990 218 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 85858511 Common - hypothetical cytosolic protein SYN_01732 115 COG1801 COG1801, Uncharacterized conserved protein Function unknown 85857901 Common - response regulator with a winged-helix DNA-binding domain SYN_00034 218 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 85859841 Common - general secretion pathway protein F SYN_00457 148 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 85860099 Common - single-strand DNA binding protein SYN_00925 213 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 85858521 Nonpathogen - hypothetical membrane protein SYN_03409 1 None None None 85858395 Nonpathogen - hypothetical cytosolic protein SYN_02297 1 None None None 85860592 Common - transcriptional regulator SYN_02988 58 COG2378 COG2378, Predicted transcriptional regulator Transcription 85860451 Common - mannose-6-phosphate isomerase / mannose-1-phosphate guanylyltransferase SYN_03119 164 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 85859535 Nonpathogen - predicted transcriptional regulator SYN_01877 6 COG5340 COG5340, Predicted transcriptional regulator Transcription 85859702 Nonpathogen - universal stress family protein N SYN_01985 1 None None None 85860083 Nonpathogen - hypothetical cytosolic protein SYN_01557 1 None None None 85860346 Nonpathogen - pbs lyase heat-like repeat protein SYN_00857 9 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 85858932 Common - transposase and inactivated derivatives SYN_03179 38 None None None 85860085 Common - queuosine biosynthesis protein SYN_01560 178 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 85859231 Common - transposase SYN_01382 55 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 85859520 Common - hypothetical protein SYN_01862 3 None None None 85860501 Common - SSU ribosomal protein S21P SYN_01767 37 None None None 85859344 Common - imidazole glycerol phosphate synthase, cyclase subunit SYN_01451 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 85858821 Common - hypothetical cytosolic protein SYN_01474 4 COG2882 FliJ, Flagellar biosynthesis chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 85859851 Common - ABC transporter ATP-binding protein SYN_00466 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 85860548 Nonpathogen - hypothetical cytosolic protein SYN_03786 1 None None None 85858588 Common - hypothetical cytosolic protein SYN_02970 67 COG1636 COG1636, Uncharacterized protein conserved in bacteria Function unknown 85858920 Common thiH thiamine biosynthesis protein ThiH SYN_02133 62 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 85858213 Common - alcohol dehydrogenase SYN_01159 200 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 85860416 Common - 3-isopropylmalate dehydratase large subunit SYN_00091 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 85859907 Common - phosphate butyryltransferase SYN_00653 60 COG0280 Pta, Phosphotransacetylase Energy production and conversion 85858455 Common - transposase SYN_03042 64 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 85859912 Common - methyl-accepting chemotaxis protein SYN_00659 19 None None None 85860638 Nonpathogen - hypothetical cytosolic protein SYN_01076 1 None None None 85860513 Common - deoxyuridine 5'-triphosphate nucleotidohydrolase SYN_01779 184 COG0756 Dut, dUTPase Nucleotide transport and metabolism 85860113 Common - ABC transporter ATP-binding protein SYN_00824 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 85860180 Nonpathogen - hypothetical membrane protein SYN_01756 2 COG4726 PilX, Tfp pilus assembly protein PilX Cell motility and secretion / Intracellular trafficking and secretion 85859034 Common - chemotaxis protein that stimulates methylation of MCP proteins SYN_00969 85 COG1871 CheD, Chemotaxis protein; stimulates methylation of MCP proteins Cell motility and secretion / Signal transduction mechanisms 85860610 Nonpathogen - iron(III) dicitrate-biding protein SYN_01049 5 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 85860471 Common - putative cephalosporin hydroxylase SYN_02654 20 COG3510 CmcI, Cephalosporin hydroxylase Defense mechanisms 85860167 Common - endonuclease SYN_00772 164 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 85857975 Common - phosphate transport system permease protein SYN_02225 224 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 85859515 Common - outer membrane protein A protein family SYN_01857 36 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 85858940 Common - iron only hydrogenase large subunit SYN_01370 184 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 85860929 Nonpathogen - hypothetical cytosolic protein SYN_00220 1 None None None 85859187 Common - RNA polymerase flagellar sigma factor SYN_02827 214 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 85860231 Nonpathogen - hypothetical cytosolic protein SYN_03017 1 None None None 85859750 Common - soluble lytic murein transglycosylase SYN_01413 154 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 85859870 Nonpathogen - hypothetical cytosolic protein SYN_00485 1 None None None 85858816 Common - flagellar hook-basal body complex protein SYN_01469 92 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 85859135 Common - flp pilus assembly protein, ATPase SYN_01496 128 COG4963 CpaE, Flp pilus assembly protein, ATPase CpaE Intracellular trafficking and secretion 85860829 Common - acyl-CoA dehydrogenase SYN_01699 160 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 85858302 Nonpathogen - hypothetical cytosolic protein SYN_02611 1 None None None 85859472 Nonpathogen - hypothetical cytosolic protein SYN_03147 1 None None None 85859017 Common - adenylosuccinate synthetase SYN_00122 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 85859807 Nonpathogen - hypothetical cytosolic protein SYN_03647 1 None None None 85858317 Common - methyl-viologen-reducing hydrogenase, delta subunit SYN_00256 99 COG1908 FrhD, Coenzyme F420-reducing hydrogenase, delta subunit Energy production and conversion 85859212 Common - glycosyltransferase SYN_02803 133 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 85861001 Common - export ABC transporter permease protein SYN_02064 124 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 85858560 Common - hypothetical membrane protein SYN_02449 7 None None None 85858761 Common - ADP-ribosylglycohydrolase SYN_02739 81 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 85859100 Common - primosomal protein N' - superfamily II helicase SYN_01336 213 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 85860842 Common - pyridoxine biosynthesis protein SYN_01685 87 COG0214 SNZ1, Pyridoxine biosynthesis enzyme Coenzyme metabolism 85860103 Common - sensory transduction protein kinase SYN_00929 223 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 85859760 Common - enoyl-CoA hydratase SYN_01309 188 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 85860733 Common - dolichyl-phosphate-mannose--protein mannosyltransferase SYN_02389 50 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 85860396 Common - histidinol-phosphate aminotransferase SYN_01164 217 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 85858957 Common - L-threonine 3-dehydrogenase SYN_00564 209 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 85859900 Common - acetyl-CoA synthetase (NDP-forming) beta subunit SYN_00646 138 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 85860281 Nonpathogen - hypothetical cytosolic protein SYN_02521 1 None None None 85859123 Common - transcriptional regulator helix turn helix SYN_01508 6 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 85857856 Nonpathogen - hypothetical cytosolic protein SYN_02041 4 None None None 85860705 Common - 2-aminobenzoate-CoA ligase SYN_02417 220 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 85859265 Common - molybdopterin biosynthesis MoeA protein SYN_02148 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 85858039 Common - rubrerythrin and thioesterase superfamily protein SYN_02559 174 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 85858466 Common - peptidyl-prolyl cis-trans isomerase SYN_00555 126 None None None 85859349 Nonpathogen - hypothetical cytosolic protein SYN_00282 1 None None None 85860749 Common - SAM-dependent methyltransferases SYN_00372 195 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 85859439 Common - phosphatidylserine decarboxylase SYN_00913 96 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 85860619 Common - tonB dependent receptor family SYN_01058 5 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 85859788 Common valS valyl-tRNA synthetase SYN_02886 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 85859774 Common - ribokinase SYN_02874 187 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 85858127 Common - hypothetical cytosolic protein SYN_00076 47 COG5319 COG5319, Uncharacterized protein conserved in bacteria Function unknown 85859939 Nonpathogen - hypothetical membrane protein SYN_03097 1 None None None 85858534 Common - chemotaxis protein methyltransferase SYN_00434 156 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 85859604 Nonpathogen - hypothetical cytosolic protein SYN_02013 13 None None None 85859698 Nonpathogen - hypothetical cytosolic protein SYN_01989 3 None None None 85859947 Common - alpha-amylase SYN_00687 165 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 85858991 Nonpathogen - hypothetical cytosolic protein SYN_03184 1 None None None 85860155 Common - ATP-dependent protease La SYN_00783 232 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 85858074 Common - ABC-type cobalamin/Fe3+-siderophore transport system, ATPase component SYN_01426 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 85859586 Common - transposase SYN_03595 90 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 85858950 Nonpathogen - hypothetical cytosolic protein SYN_03505 1 None None None 85859633 Common - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase SYN_02454 190 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 85860547 Common - thiol:disulfide interchange protein SYN_01815 151 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 85858772 Nonpathogen - hypothetical cytosolic protein SYN_02731 1 None None None 85860622 Common - hypothetical cytosolic protein SYN_01061 17 COG2014 COG2014, Uncharacterized conserved protein Function unknown 85858244 Common - nucleotide-sugar aminotransferase SYN_01128 193 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 85859896 Nonpathogen - hypothetical cytosolic protein SYN_00508 1 None None None 85858886 Common - ABC-type sugar transport system, periplasmic component SYN_00391 90 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 85860120 Common - glycosyltransferase SYN_00817 225 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 85859594 Nonpathogen - hypothetical cytosolic protein SYN_02022 1 None None None 85858224 Nonpathogen - hypothetical cytosolic protein SYN_01148 1 None None None 85859142 Common - flp/fap pilin component SYN_01489 4 COG3847 Flp, Flp pilus assembly protein, pilin Flp Intracellular trafficking and secretion 85860858 Nonpathogen - hypothetical cytosolic protein SYN_01669 1 None None None 85860851 Common - formate dehydrogenase activity protein SYN_01677 137 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 85858334 Common - ABC transporter substrate-binding protein SYN_02358 93 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 85860883 Common - Fe-S oxidoreductase SYN_01643 159 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 85859157 Common - tryptophanyl-tRNA synthetase SYN_02857 247 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 85858231 Common - glycosyltransferase SYN_01141 172 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 85860001 Common - outer membrane protein slp precursor SYN_00736 21 COG3065 Slp, Starvation-inducible outer membrane lipoprotein Cell envelope biogenesis, outer membrane 85859925 Common - hypothetical membrane protein SYN_00670 16 None None None 85860543 Nonpathogen - hypothetical cytosolic protein SYN_03783 1 None None None 85860360 Common - pyrazinamidase / nicotinamidase SYN_01201 124 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 85860752 Common - benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB SYN_00369 33 COG1775 HgdB, Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB Amino acid transport and metabolism 85859390 Common - succinyl-diaminopimelate desuccinylase SYN_02795 197 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 85859817 Common - appr-1-p histone processing protein SYN_01003 116 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 85860772 Common - pentapeptide repeat domain protein SYN_00349 113 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 85858905 Common - selenide water dikinase SYN_02118 113 COG0709 SelD, Selenophosphate synthase Amino acid transport and metabolism 85857961 Common - nitrogen regulatory protein PII SYN_02212 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 85859447 Common - prolyl-tRNA synthetase SYN_00905 249 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 85859868 Common - ATP-dependent helicase, dinG family SYN_00483 132 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 85860713 Common - hypothetical cytosolic protein SYN_02409 2 None None None 85860289 Common - phosphate butyryltransferase SYN_01212 61 COG0280 Pta, Phosphotransacetylase Energy production and conversion 85859732 Common - peptidyl-tRNA hydrolase SYN_02769 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 85859098 Common - superoxide dismutase (Fe) SYN_03202 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 85858238 Common - oligosaccharide translocase SYN_01134 9 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 85858949 Nonpathogen - hypothetical cytosolic protein SYN_01361 2 None None None 85859556 Common - istB-like ATP binding protein SYN_01899 120 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 85859238 Common - Fe-S oxidoreductase SYN_03213 156 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 85859985 Common - hypothetical membrane protein SYN_00721 8 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 85857849 Common - DNA gyrase subunit A SYN_02048 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 85858136 Common - LSU ribosomal protein L10 SYN_00067 213 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 85860560 Common - endopeptidase SYN_00294 191 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 85860254 Nonpathogen - hypothetical cytosolic protein SYN_02495 1 None None None 85859919 Common - transposase SYN_03092 84 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 85860456 Common - undecaprenyl-phosphate alpha-N-acetylglucosaminephosphotransferase SYN_02669 172 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 85859192 Nonpathogen - hypothetical membrane protein SYN_02823 1 None None None 85858329 Common - hypothetical membrane protein SYN_03357 13 COG0679 COG0679, Predicted permeases General function prediction only 85858053 Common - moxR-like ATPase with AAA domain SYN_02572 94 COG0714 COG0714, MoxR-like ATPases General function prediction only 85861013 Common - chromosome partitioning protein SYN_02053 225 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 85858630 Common - activator of 2-hydroxyglutaryl-CoA dehydratase SYN_01576 65 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 85860777 Common - predicted permease SYN_00343 100 COG0701 COG0701, Predicted permeases General function prediction only 85858489 Common - UDP-glucose 6-dehydrogenase SYN_00532 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 85858833 Common - ABC-type transport system, ATP-binding component SYN_00410 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 85858146 Common - LSU ribosomal protein L3P SYN_00985 220 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 85857930 Common - pyruvate:ferredoxin oxidoreductase alpha subunit SYN_00155 114 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 85857878 Common - adenine-specific DNA methylase containing a Zn-ribbon SYN_00011 18 COG1743 COG1743, Adenine-specific DNA methylase containing a Zn-ribbon DNA replication, recombination, and repair 85858342 Nonpathogen - hypothetical membrane protein SYN_02350 1 COG4371 COG4371, Predicted membrane protein Function unknown 85860874 Common - radical SAM superfamily protein SYN_01651 88 COG1242 COG1242, Predicted Fe-S oxidoreductase General function prediction only 85858141 Nonpathogen - hypothetical cytosolic protein SYN_03310 1 None None None 85858779 Nonpathogen - hypothetical cytosolic protein SYN_02724 1 None None None 85859204 Common - flagellin and related hook-associated proteins SYN_02811 98 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 85860896 Common - glutamine synthetase SYN_01628 229 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 85858188 Common - 2'-5' RNA ligase SYN_02029 123 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 85858856 Nonpathogen - hypothetical membrane protein SYN_03477 1 None None None 85857890 Common - ABC transporter permease protein SYN_00023 18 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 85858310 Common - glycosyltransferase SYN_00250 31 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 85860495 Nonpathogen - hypothetical protein SYN_03774 1 None None None 85859689 Nonpathogen - hypothetical membrane protein SYN_01089 1 None None None 85860421 Nonpathogen - hypothetical cytosolic protein SYN_00098 1 None None None 85858181 Common - SSU ribosomal protein S9P SYN_00233 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 85859791 Common - DNA mismatch repair protein mutL SYN_02889 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 85859617 Common - hypothetical cytosolic protein SYN_02000 14 None None None 85859333 Common - ABC-type phosphate transport system, periplasmic component SYN_00056 160 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 85858747 Common - type II restriction enzyme, methylase subunit SYN_02752 27 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 85858608 Nonpathogen - hypothetical cytosolic protein SYN_03430 1 None None None 85859632 Common - rRNA methylase SYN_02455 132 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 85859978 Common - sensory domain linked to a LuxR regulatory protein SYN_00715 137 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 85860306 Common - DNA-binding protein HU SYN_01228 201 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 85860311 Common - response regulator receiver domain with sensory domain SYN_01234 225 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 85857988 Common - NADH-quinone oxidoreductase chain F SYN_00631 168 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 85860197 Nonpathogen - hypothetical membrane protein SYN_00587 3 None None None 85859710 Common - cytochrome d ubiquinol oxidase subunit I SYN_01976 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 85858190 Common - phosphatidylglycerophosphatase A SYN_02031 35 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 85860224 Common - hypothetical cytosolic protein SYN_00618 15 None None None 85860494 Common - GTPase SYN_01762 219 COG2262 HflX, GTPases General function prediction only 85860654 Nonpathogen - hypothetical membrane protein SYN_02992 1 None None None 85857963 Common - response regulator with sigma 54 interaction domain SYN_02214 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 85859312 Common - PAS sensory box/GGDEF family protein SYN_02543 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 85858784 Common - HD domain family protein SYN_02718 9 None None None 85859883 Common - hypothetical cytosolic protein SYN_00496 17 COG4694 COG4694, Uncharacterized protein conserved in bacteria Function unknown 85860605 Common - xdhC protein SYN_01045 112 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 85860276 Nonpathogen - hypothetical cytosolic protein SYN_02516 1 None None None 85860221 Nonpathogen - hypothetical membrane protein SYN_00616 1 None None None 85857997 Common - phosphohydrolase SYN_01959 13 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 85859611 Common - pirin SYN_02006 148 COG1741 COG1741, Pirin-related protein General function prediction only 85858636 Nonpathogen - hypothetical cytosolic protein SYN_01951 1 None None None 85859941 Nonpathogen - hypothetical cytosolic protein SYN_00682 1 None None None 85858439 Nonpathogen - hydrolase of the HD superfamily SYN_02251 25 COG1353 COG1353, Predicted hydrolase of the HD superfamily (permuted catalytic motifs) General function prediction only 85858497 Common - threonyl-tRNA synthetase SYN_01717 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 85858748 Nonpathogen - hypothetical membrane protein SYN_02751 2 None None None 85859618 Common - pyruvate formate-lyase activating enzyme SYN_01999 38 COG1313 PflX, Uncharacterized Fe-S protein PflX, homolog of pyruvate formate lyase activating proteins General function prediction only 85858473 Common - ATP synthase B chain SYN_00548 46 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 85859929 Common - ATPase SYN_00674 77 COG0433 COG0433, Predicted ATPase General function prediction only 85858642 Nonpathogen - hypothetical cytosolic protein SYN_01754 1 None None None 85858665 Nonpathogen - hypothetical cytosolic protein SYN_02912 1 None None None 85859315 Common - hypothetical cytosolic protein SYN_02540 24 COG4866 COG4866, Uncharacterized conserved protein Function unknown 85859670 Common - anthranilate synthase component I SYN_01947 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 85859878 Nonpathogen - hypothetical cytosolic protein SYN_00491 1 None None None 85860417 Common - aconitase C-terminal domain protein SYN_00092 211 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 85860942 Common - predicted permease SYN_00207 181 COG0628 PerM, Predicted permease General function prediction only 85858741 Common - quinolinate synthetase SYN_02758 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 85858867 Nonpathogen - hypothetical cytosolic protein SYN_01323 1 None None None 85858860 Common - glycogen phosphorylase SYN_01331 140 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 85859984 Common - exported Fe-S-cluster-containing protein SYN_00720 161 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 85858692 Nonpathogen - hypothetical cytosolic protein SYN_00876 1 None None None 85860353 Common - transcriptional regulator, TetR family SYN_00850 70 COG1309 AcrR, Transcriptional regulator Transcription 85858129 Common - hypothetical cytosolic protein SYN_00074 66 COG1355 COG1355, Predicted dioxygenase General function prediction only 85860865 Common - SoxR-reducing system protein RsxE SYN_01661 76 COG4660 RnfE, Predicted NADH:ubiquinone oxidoreductase, subunit RnfE Energy production and conversion 85858676 Nonpathogen - bacterial regulatory protein, Fis family SYN_02924 2 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 85859004 Common - IS111A/IS1328/IS1533 family of transposase SYN_00113 49 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 85860816 Nonpathogen - hypothetical cytosolic protein SYN_01714 1 None None None 85858320 Common - Fe-S oxidoreductase SYN_00259 156 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 85859630 Common - dimethylallyltransferase / geranyltranstransferase / geranylgeranyl pyrophosphate synthetase SYN_02457 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 85858720 Common - tolB protein SYN_00188 173 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 85857934 Common - 2Fe-2S iron-sulfur cluster domain with dehydrogenase SYN_00151 180 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 85858682 Common - outer membrane lipoprotein carrier protein SYN_00884 51 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 85860630 Nonpathogen - hypothetical cytosolic protein SYN_01070 1 None None None 85859105 Common - oligopeptide transport system permease protein SYN_01341 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 85859584 Common - virulence factor protein SYN_00104 195 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 85859818 Nonpathogen - protein involved in biosynthesis of molybdopterin SYN_01004 9 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 85859303 Common - exodeoxyribonuclease V beta chain SYN_02552 222 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 85860068 Nonpathogen - hypothetical cytosolic protein SYN_01544 1 None None None 85858936 Common - sensory transduction protein kinase SYN_01374 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 85859221 Common - transposase and inactivated derivatives SYN_03210 38 None None None 85858717 Common - tolQ protein SYN_00185 133 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 85859871 Nonpathogen - hypothetical cytosolic protein SYN_00486 8 COG0433 COG0433, Predicted ATPase General function prediction only 85860988 Common - transcriptional regulator, tetR family SYN_02076 98 COG1309 AcrR, Transcriptional regulator Transcription 85860742 Common - hypothetical cytosolic protein SYN_00378 52 COG3222 COG3222, Uncharacterized protein conserved in bacteria Function unknown 85859705 Common - grpE protein SYN_01981 230 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 85858402 Common - phage-related tail protein SYN_02290 19 None None None 85859915 Nonpathogen - hypothetical cytosolic protein SYN_00662 3 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 85860747 Common - hypothetical cytosolic protein SYN_00374 3 None None None 85860881 Common - heterodisulfide reductase, subunit A SYN_01645 46 COG1148 HdrA, Heterodisulfide reductase, subunit A and related polyferredoxins Energy production and conversion 85860982 Nonpathogen - hypothetical membrane protein SYN_02083 1 None None None 85858046 Common - nitroreductase family protein SYN_02565 15 COG0778 NfnB, Nitroreductase Energy production and conversion 85858505 Common - transcriptional regulator, MerR family SYN_01725 94 COG0789 SoxR, Predicted transcriptional regulators Transcription 85860499 Common - DNA polymerase III, delta subunit SYN_01765 38 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 85858251 Common - transcriptional regulator, sigma-54-dependent SYN_01122 191 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 85860008 Common - hypothetical membrane protein SYN_00742 45 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 85858054 Common - hypothetical cytosolic protein SYN_02573 58 COG3825 COG3825, Uncharacterized protein conserved in bacteria Function unknown 85857957 Common - Fe2+ transport system protein B SYN_02208 153 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 85858710 Common - 2-oxoacid ferredoxin oxidoreductase, alpha subunit SYN_03162 107 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 85857857 Nonpathogen - hypothetical cytosolic protein SYN_03225 1 None None None 85858085 Nonpathogen - hypothetical cytosolic protein SYN_01436 1 None None None 85858791 Nonpathogen - hypothetical cytosolic protein SYN_03168 1 None None None 85859970 Common - RNA-binding protein SYN_00708 62 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 85859145 Common - cell wall-associated hydrolase SYN_01486 163 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 85860259 Common - pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit SYN_02500 69 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 85859490 Common - predicted hydrolase SYN_01831 28 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 85860522 Common nusA transcription elongation factor NusA SYN_01789 227 COG0195 NusA, Transcription elongation factor Transcription 85859681 Nonpathogen - hypothetical cytosolic protein SYN_01082 1 None None None 85860968 Common - F0F1-type ATP synthase, beta subunit SYN_02097 238 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 85858409 Common - hypothetical cytosolic protein SYN_02283 4 None None None 85858532 Common - Fe-S oxidoreductase SYN_00436 60 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 85860071 Common - fibronectin type III domain protein SYN_01547 7 COG3889 COG3889, Predicted solute binding protein General function prediction only 85860921 Common - histidine kinase SYN_00228 25 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 85859934 Common - lipase SYN_00679 139 COG0657 Aes, Esterase/lipase Lipid metabolism 85858105 Common - ABC-type transport system involved in resistance to organic solvents, periplasmic component SYN_01264 104 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 85858727 Common - hypothetical cytosolic protein SYN_00195 74 COG1912 COG1912, Uncharacterized conserved protein Function unknown 85857894 Common groEL chaperonin GroEL SYN_00027 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 85860697 Common - NADH-quinone oxidoreductase chain E SYN_02425 157 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 85860485 Common - long-chain-fatty-acid--CoA ligase SYN_02640 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 85860228 Nonpathogen - hypothetical cytosolic protein SYN_03018 1 None None None 85858699 Common - hypothetical cytosolic protein SYN_00128 12 None None None 85858573 Common - tRNA-dihydrouridine synthase SYN_02436 219 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 85859688 Nonpathogen - hypothetical cytosolic protein SYN_03001 1 None None None 85858027 Common - GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone-4-phosphate synthase SYN_02371 232 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 85860529 Common rho transcription termination factor Rho SYN_01798 208 COG1158 Rho, Transcription termination factor Transcription 85859593 Common - endopeptidase SYN_02023 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 85859251 Common - nitroreductase family protein SYN_00273 45 COG0778 NfnB, Nitroreductase Energy production and conversion 85859529 Nonpathogen - hypothetical membrane protein SYN_01871 2 None None None 85859401 Common - protein ERFK SYN_02183 66 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 85860054 Common - Mg/Co/Ni transporter MgtE domain protein SYN_01529 169 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 85859824 Common thiG thiazole synthase SYN_00440 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 85860534 Common - peptide deformylase SYN_01803 211 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 85858185 Common - alanyl-tRNA synthetase SYN_02026 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 85858370 Nonpathogen - hypothetical cytosolic protein SYN_03368 1 None None None 85859045 Nonpathogen - hypothetical cytosolic protein SYN_00958 2 COG5581 COG5581, Predicted glycosyltransferase Cell envelope biogenesis, outer membrane 85860122 Nonpathogen - dolichyl-phosphate-mannose-protein mannosyltransferase proteins SYN_00815 3 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 85859228 Common - rubredoxin SYN_01385 118 COG1773 COG1773, Rubredoxin Energy production and conversion 85860319 Common - phosphoenolpyruvate synthase SYN_01243 40 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 85860199 Common - GTPase EngB SYN_00589 188 COG0218 COG0218, Predicted GTPase General function prediction only 85858574 Nonpathogen - hypothetical cytosolic protein SYN_03133 1 None None None 85858165 Common - LSU ribosomal protein L30P SYN_01593 147 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 85859116 Common - ATPase SYN_01515 66 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 85859300 Common - radical SAM superfamily protein SYN_02555 74 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 85859751 Common - tetratricopeptide repeat family protein SYN_01414 147 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 85860766 Nonpathogen - hypothetical membrane protein SYN_00355 23 None None None 85858731 Common - N-(5'-phosphoribosyl)anthranilate isomerase SYN_02481 146 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 85858152 Common rpsC 30S ribosomal protein S3 SYN_00991 234 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 85860666 Common - transcriptional regulator, MarR family SYN_02624 105 COG1846 MarR, Transcriptional regulators Transcription 85860998 Common - hypothetical protein SYN_02067 27 COG3009 COG3009, Uncharacterized protein conserved in bacteria Function unknown 85860639 Common - sensor proteinLuxQ SYN_01077 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 85858214 Common - hydroxyacylglutathione hydrolase SYN_01158 187 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 85859834 Nonpathogen - hypothetical protein SYN_00450 1 None None None 161347550 Common - phospho-2-dehydro-3-heoxyheptonate aldolase SYN_02256 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 85859358 Nonpathogen - hypothetical cytosolic protein SYN_01962 1 COG1565 COG1565, Uncharacterized conserved protein Function unknown 85859621 Nonpathogen - hypothetical protein SYN_01996 1 None None None 85859191 Nonpathogen - hypothetical cytosolic protein SYN_03532 1 None None None 85859482 Common - ATPase SYN_01822 85 COG0433 COG0433, Predicted ATPase General function prediction only 85858591 Common - phosphoenolpyruvate synthase SYN_02966 234 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 85858942 Nonpathogen - hypothetical cytosolic protein SYN_01368 1 None None None 85858293 Common - bifunctional aspartyl-tRNA synthetase/aspartyl/glutamyl-tRNA amidotransferase subunit C SYN_02602 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 85858269 Common - hypothetical cytosolic protein SYN_01104 21 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 85859267 Common - hypothetical cytosolic protein SYN_02150 78 COG1259 COG1259, Uncharacterized conserved protein Function unknown 85858452 Common - uncharacterized protein predicted to be involved in DNA repair SYN_02241 99 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 85860618 Common - methyltransferase SYN_01057 11 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 85859738 Common - transposase SYN_01920 63 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 85859241 Common - methyl-viologen-reducing hydrogenase, delta subunit SYN_03216 99 COG1908 FrhD, Coenzyme F420-reducing hydrogenase, delta subunit Energy production and conversion 85860804 Nonpathogen - hypothetical cytosolic protein SYN_00313 1 None None None 85858258 Nonpathogen - hypothetical membrane protein SYN_01115 1 None None None 85859758 Nonpathogen - hypothetical cytosolic protein SYN_03636 1 None None None 85858311 Nonpathogen - hypothetical cytosolic protein SYN_00251 1 None None None 85859511 Common - merR family regulatory protein SYN_01853 29 COG3311 AlpA, Predicted transcriptional regulator Transcription 85858275 Common - N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase SYN_01098 108 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 85858687 Common - alpha-amylase SYN_00880 23 COG1449 COG1449, Alpha-amylase/alpha-mannosidase Carbohydrate transport and metabolism 161347548 Common secA preprotein translocase subunit SecA SYN_01036 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 85858773 Nonpathogen - hypothetical protein SYN_02730 5 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 85858923 Common - formate dehydrogenase, iron-sulfur subunit SYN_02137 209 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 85859849 Common - hypothetical cytosolic protein SYN_00464 6 None None None 85860142 Common - radical SAM superfamily protein SYN_00795 194 COG1243 ELP3, Histone acetyltransferase Transcription / Chromatin structure and dynamics 85860991 Common - acriflavin resistance plasma membrane protein SYN_02074 180 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 85860831 Common - 3-hydroxydecanoyl-(acyl carrier protein) dehydratase SYN_01697 85 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 85858622 Common - exonuclease SYN_00200 161 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 85860014 Common - acetyl-CoA synthetase beta subunit SYN_00748 165 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 85860377 Nonpathogen - pyruvoyl-dependent arginine decarboxylase SYN_01184 27 COG1945 COG1945, Uncharacterized conserved protein Function unknown 85859717 Common - predicted periplasmic or secreted lipoprotein SYN_03003 43 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 85860838 Nonpathogen - hypothetical cytosolic protein SYN_01689 2 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 85858995 Nonpathogen - hypothetical cytosolic protein SYN_03186 1 None None None 85860449 Common - hypothetical cytosolic protein SYN_02676 21 COG5360 COG5360, Uncharacterized protein conserved in bacteria Function unknown 85859416 Common - elongation factor G SYN_02930 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 85860384 Common - metallo-beta-lactamase superfamily protein SYN_01177 51 COG1237 COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II General function prediction only 85858417 Common - glutamyl-tRNA reductase SYN_02274 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 85858335 Common - anti-sigma regulatory factor SYN_02357 36 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 85859289 Nonpathogen - hypothetical membrane protein SYN_03554 1 None None None 85860734 Common - cobalt-zinc-cadmium resistance protein SYN_02388 211 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 85859297 Common - beta-lactamase class A SYN_01571 71 COG2367 PenP, Beta-lactamase class A Defense mechanisms 85859411 Common - hypothetical cytosolic protein SYN_03569 3 None None None 85858364 Common - transposase SYN_02327 47 None None None 85858617 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 SYN_02940 17 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 85860031 Common - imidazoleglycerol-phosphate dehydratase SYN_03108 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 85858021 Common - ATP-dependent Clp protease adaptor protein SYN_02377 119 COG2127 COG2127, Uncharacterized conserved protein Function unknown 85860111 Common - SAM-dependent methyltransferase SYN_00826 112 COG4976 COG4976, Predicted methyltransferase (contains TPR repeat) General function prediction only 85858286 Common - acetyl-CoA CoA transferase / acetyltransferase SYN_02594 146 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 85860684 Common - export ABC transporter permease protein SYN_00243 136 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 85858015 Common - phosphoenolpyruvate synthase SYN_02383 29 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 85859223 Common - argininosuccinate synthase SYN_01390 188 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 85858377 Nonpathogen - hypothetical cytosolic protein SYN_02314 1 COG1017 Hmp, Hemoglobin-like flavoprotein Energy production and conversion 85858850 Nonpathogen - hypothetical cytosolic protein SYN_03066 1 None None None 85860261 Common - succinyl-CoA synthetase alpha chain SYN_02502 216 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 85860934 Common - ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components SYN_00216 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 85859434 Common - undecaprenyl pyrophosphate synthetase SYN_00918 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 85859747 Common - aconitate hydratase SYN_01409 223 COG1048 AcnA, Aconitase A Energy production and conversion 85858705 Common - tetratricopeptide repeat family protein SYN_00134 112 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 85860045 Nonpathogen - hypothetical membrane protein SYN_00040 7 COG3242 COG3242, Uncharacterized protein conserved in bacteria Function unknown 85858752 Nonpathogen - hypothetical cytosolic protein SYN_02747 6 None None None 85860135 Nonpathogen - esterase-like protein SYN_00801 11 COG3545 COG3545, Predicted esterase of the alpha/beta hydrolase fold General function prediction only 85858220 Common - hypothetical cytosolic protein SYN_01152 4 None None None 85859443 Common - phosphopantetheine adenylyltransferase SYN_00909 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 85859454 Nonpathogen - hypothetical membrane protein SYN_03576 1 None None None 85859853 Common - sodium-dependent phosphate transporter SYN_00468 91 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 85859075 Common - hypothetical membrane protein SYN_00425 3 None None None 85859205 Common - carbon storage regulator SYN_02810 84 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 85860375 Common - iron-sulfur cluster and nucleotide-binding protein SYN_01186 40 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 85859561 Common - ATPases of the AAA family SYN_01904 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 85860473 Common - CDP-4-dehydro-6-deoxy-D-gulose 4-reductase SYN_02652 228 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 85858669 Common - FAD-dependent dehydrogenase SYN_02917 83 COG2509 COG2509, Uncharacterized FAD-dependent dehydrogenases General function prediction only 85858445 Nonpathogen - hypothetical cytosolic protein SYN_02245 9 None None None 85860898 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein SYN_01626 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 85858038 Nonpathogen - hypothetical cytosolic protein SYN_03245 1 None None None 85859935 Nonpathogen - hypothetical cytosolic protein SYN_00680 1 None None None 85860453 Nonpathogen - hypothetical protein SYN_02672 1 None None None 85858568 Nonpathogen - hypothetical cytosolic protein SYN_02441 1 None None None 85859237 Common - 4Fe-4S protein SYN_01376 17 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 85859334 Common - ABC-type phosphate transport system, permease component SYN_00057 232 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 85860492 Nonpathogen - hypothetical cytosolic protein SYN_03117 1 None None None 85858774 Nonpathogen - hypothetical protein SYN_02729 1 None None None 85858260 Common - UDP-N-acetyl-D-galactosamine 6-dehydrogenase SYN_01113 206 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 85858131 Common - LSU ribosomal protein L33P SYN_00072 79 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 85858300 Common - acetyl-CoA synthetase beta subunit SYN_02609 140 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 85860056 Common - aspartate carbamoyltransferase SYN_01532 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 85858487 Common - phosphoesterase SYN_00534 102 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 85860302 Common - metallo cofactor biosynthesis protein SYN_01224 18 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 85859600 Nonpathogen - hypothetical cytosolic protein SYN_02016 1 None None None 85860628 Common - phosphoribosylaminoimidazole carboxylase ATPase subunit SYN_01067 32 COG3837 COG3837, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 85858506 Nonpathogen - hypothetical cytosolic protein SYN_01726 6 None None None 85860148 Common - transposase SYN_00790 34 None None None 85859507 Common - ATP-dependent DNA helicase SYN_01849 227 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 85858337 Common - acetyltransferase SYN_02355 6 COG0456 RimI, Acetyltransferases General function prediction only 85859606 Common - DNA polymerase IV SYN_02012 184 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 85858633 Common - signal transduction histidine kinase SYN_01954 160 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 85859210 Common - flagellar hook and flagellar capping protein SYN_02805 131 COG1345 FliD, Flagellar capping protein Cell motility and secretion 85859953 Common - pyruvate synthase alpha chain SYN_00692 122 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 85857986 Common - formate dehydrogenase, catalytic subunit SYN_00629 190 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 85859072 Common - integrin-like repeat protein SYN_00931 9 COG5616 COG5616, Predicted integral membrane protein Function unknown 85860569 Common - hypothetical cytosolic protein SYN_02983 21 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 85858092 Common - hypothetical cytosolic protein SYN_01443 8 COG1102 Cmk, Cytidylate kinase Nucleotide transport and metabolism 85859047 Common - ABC-type Mn2+/Zn2+ transport systems, permease component SYN_00956 195 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 85857926 Common - fumarate hydratase SYN_00159 148 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 85859156 Common - DNA-binding protein HU SYN_02859 214 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 85858544 Nonpathogen - hypothetical cytosolic protein SYN_03129 1 None None None 85858018 Common - signal transduction histidine kinase SYN_02380 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 85859792 Common - hypothetical protein SYN_02890 7 COG3018 COG3018, Uncharacterized protein conserved in bacteria Function unknown 85859812 Common - coproporphyrinogen oxidase (NAD) SYN_00998 56 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 85861003 Common - hypothetical cytosolic protein SYN_03856 38 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 85857850 Common - hypothetical cytosolic protein SYN_02047 47 COG1371 COG1371, Uncharacterized conserved protein Function unknown 85858839 Nonpathogen - hypothetical cytosolic protein SYN_00404 1 None None None 85858916 Common - SAM-dependent methyltransferase SYN_02129 35 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 85859263 Common - 4Fe-4S protein SYN_03219 21 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 85859643 Common - GTP pyrophosphokinase / guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase SYN_03611 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 85859346 Common - membrane fusion protein SYN_00285 75 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 85860688 Nonpathogen - hypothetical cytosolic protein SYN_02435 3 None None None 85858154 Nonpathogen - hypothetical membrane protein SYN_03312 1 None None None 85858978 Common - sir2 family of NAD+-dependent deacetylase SYN_01020 152 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 85858887 Nonpathogen - hypothetical cytosolic protein SYN_00392 1 None None None 85860427 Nonpathogen - hypothetical cytosolic protein SYN_02698 1 None None None 85858031 Common - serine hydroxymethyltransferase SYN_02367 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 85860524 Common - histidinol dehydrogenase SYN_01792 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 85860857 Nonpathogen - hypothetical membrane protein SYN_01671 1 None None None 85857944 Nonpathogen - ribulose-5-phosphate 4-epimerase and related epimerases and aldolases SYN_00141 18 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 85859083 Common - S-adenosylmethionine synthetase SYN_00417 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 85858694 Common - outer membrane protein SYN_00874 97 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 85859436 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase SYN_00916 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 85860283 Common - rubrerythrin SYN_02523 79 COG1592 COG1592, Rubrerythrin Energy production and conversion 85859516 Common - protein-disulfide isomerase SYN_01858 44 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 85860672 Common trkA potassium transporter peripheral membrane component SYN_02618 161 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 85859129 Nonpathogen - hypothetical cytosolic protein SYN_01502 1 None None None 85858076 Common - HD domain protein SYN_01428 141 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 85858163 Common - LSU ribosomal protein L18P SYN_01591 216 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 85858907 Nonpathogen - hypothetical cytosolic protein SYN_02120 1 None None None 85859821 Common - hypothetical protein SYN_01007 49 COG4198 COG4198, Uncharacterized conserved protein Function unknown 85859121 Common - hypothetical cytosolic protein SYN_01510 3 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 85858663 Common - ATPase protein SYN_02911 56 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 85860565 Common - molybdopterin-guanine dinucleotide biosynthesis protein B SYN_00289 113 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 85858674 Common - CTP synthetase SYN_02922 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 85859092 Common - cytidylate kinase SYN_03196 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 85859769 Common - hydantoinase/oxoprolinase family SYN_02869 117 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 85858993 Nonpathogen - hypothetical cytosolic protein SYN_03511 1 None None None 85858208 Common - predicted phosphohydrolase SYN_00525 120 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 85858223 Common - 3-oxoacyl-[acyl-carrier-protein] synthase III SYN_01149 169 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 85860188 Common - diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase SYN_00578 233 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 85859781 Common - cell division protein SYN_03643 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 85859463 Common - homoserine dehydrogenase SYN_00890 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 85860244 Nonpathogen - hypothetical cytosolic protein SYN_03013 1 None None None 85859327 Common - 1,4-dihydroxy-2-naphthoate polyprenyltransferase SYN_02527 109 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 85859486 Common - hypothetical cytosolic protein SYN_01826 22 None None None 85860181 Common - hypothetical membrane protein SYN_01757 22 COG4966 PilW, Tfp pilus assembly protein PilW Cell motility and secretion / Intracellular trafficking and secretion 85861011 Common - rRNA methylase, spoU family SYN_02055 155 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 85859917 Common - hypothetical cytosolic protein SYN_00663 20 COG1751 COG1751, Uncharacterized conserved protein Function unknown 85860758 Common - glutamate synthase [NADPH] small chain SYN_00363 54 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 85860984 Common - phosphate butyryltransferase SYN_02081 62 COG0280 Pta, Phosphotransacetylase Energy production and conversion 85858890 Nonpathogen - hypothetical cytosolic protein SYN_03176 2 None None None 85858915 Common - acyl-CoA dehydrogenase, long-chain specific SYN_02128 163 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 85860562 Nonpathogen - transcriptional regulator-like protein SYN_00293 1 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 85860298 Nonpathogen - hypothetical cytosolic protein SYN_01221 1 None None None 85859981 Common - transcriptional regulator SYN_00717 53 COG1733 COG1733, Predicted transcriptional regulators Transcription 85860586 Common - hypothetical cytosolic protein SYN_02475 55 COG3649 COG3649, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 85860511 Common - septum formation initiator SYN_03778 10 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 85858921 Common - biotin synthase SYN_02134 69 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 85859088 Common - anaerobic ribonucleoside triphosphate reductase SYN_03522 115 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 85860299 Common - sensory transduction protein PAS domain SYN_01222 66 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 85858422 Nonpathogen - hypothetical cytosolic protein SYN_03386 1 None None None 85860317 Common - cbs domain containing protein SYN_01241 13 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 85858881 Common - phosphate transport regulator SYN_00386 76 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 85860488 Common - electron transfer flavoprotein alpha-subunit SYN_02637 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 85860779 Common - transcriptional regulator, arsR family SYN_00341 157 COG0640 ArsR, Predicted transcriptional regulators Transcription 85860080 Common - general secretory pathway protein L SYN_01555 14 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 85860174 Common - SSU ribosomal protein S16P SYN_00765 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 85860164 Common - two-component response regulator SYN_00775 218 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 85860097 Common - lipoprotein releasing system, permease component SYN_00923 200 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 85860645 Nonpathogen - hypothetical cytosolic protein SYN_02991 1 None None None 85858526 Common - UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase SYN_01746 208 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 85858186 Common - regulotory protein SYN_02027 43 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 85858554 Common rpmA 50S ribosomal protein L27 SYN_01352 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 85859022 Nonpathogen - hypothetical cytosolic protein SYN_00980 1 None None None 85857896 Common - molecular chaperone SYN_00029 151 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 85859243 Common - transposase SYN_00665 84 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 85860904 Nonpathogen - hypothetical cytosolic protein SYN_01620 1 None None None 85860679 Nonpathogen - hypothetical cytosolic protein SYN_00238 8 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 85858480 Common - SAM-dependent methyltransferase SYN_00541 115 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 85859708 Common - putative ABC transporter ATP-binding protein SYN_01978 247 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 85860907 Nonpathogen - hypothetical cytosolic protein SYN_01617 1 None None None 85859567 Nonpathogen - hypothetical cytosolic protein SYN_01910 7 None None None 85857990 Common - formate dehydrogenase iron-sulfur subunit SYN_00633 163 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 85858237 Nonpathogen - hypothetical cytosolic protein SYN_01135 1 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 85860106 Nonpathogen - hypothetical cytosolic protein SYN_00832 1 None None None 85857900 Common - hypothetical membrane protein SYN_00033 74 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 85858490 Common - UDP-D-glucuronate carboxy-lyase SYN_00531 234 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 85860233 Nonpathogen - hypothetical cytosolic protein SYN_03016 1 None None None 85859756 Common - putative tRNA (5-methylaminomethyl-2-thiouridylate) -methyltransferase / fibronectin/fibrinogen-binding protein SYN_01419 42 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 85859655 Common - glucose/sorbosone dehydrogenase SYN_01932 129 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 85859164 Common - dihydroorotate dehydrogenase, catalytic subunit SYN_02850 232 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 85859035 Common - HD domain protein with metal dependent phosphohydrolase SYN_00968 61 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 85860041 Common - lipoprotein, ComL family SYN_00044 125 COG4105 ComL, DNA uptake lipoprotein General function prediction only 85860034 Common - phosphoribosyl-AMP cyclohydrolase SYN_03110 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 85860578 Nonpathogen - hypothetical cytosolic protein SYN_02466 1 None None None 85860774 Common - transcriptional regulator, ArsR family SYN_00347 159 COG0640 ArsR, Predicted transcriptional regulators Transcription 85858908 Common - transcriptional regulator, LysR family SYN_02121 191 COG0583 LysR, Transcriptional regulator Transcription 85860398 Common - SAM-dependent methyltransferase SYN_01163 100 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 85859388 Common - metal-dependent phosphohydrolase SYN_02793 56 COG1480 COG1480, Predicted membrane-associated HD superfamily hydrolase General function prediction only 85860406 Common - iron-sulfur cluster assembly/repair protein SYN_00081 239 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 85858475 Common - ATP synthase alpha chain SYN_00546 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 85860328 Common - mosC domain protein SYN_01252 42 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 85859976 Nonpathogen - hypothetical cytosolic protein SYN_03686 3 None None None 85858875 Nonpathogen - hypothetical cytosolic protein SYN_01315 1 None None None 85860063 Common - universal stress protein family SYN_01539 141 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 85858755 Common - transposase SYN_02744 85 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 85859103 Common - iojap protein family SYN_01339 194 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 85859571 Common - hypothetical cytosolic protein SYN_01915 20 COG2253 COG2253, Uncharacterized conserved protein Function unknown 85860205 Common - Ni-Fe hydrogenase precursor-specific chaperone SYN_00597 53 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 85860796 Nonpathogen - hypothetical cytosolic protein SYN_00322 1 None None None 85860798 Common - hypothetical cytosolic protein SYN_00319 13 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 85858399 Common - mu-like prophage Flumu tail sheath protein SYN_02293 21 COG4386 COG4386, Mu-like prophage tail sheath protein gpL General function prediction only 85860415 Common - 2-isopropylmalate synthase SYN_00090 217 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 85859639 Common - DNA polymerase III, gamma subunit SYN_02985 217 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 85860616 Common - iron(III) dicitrate transport system permease protein SYN_01055 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 85859963 Nonpathogen - hypothetical membrane protein SYN_03683 2 None None None 85857875 Common - ATPase of the AAA+ superfamily SYN_00008 35 COG1483 COG1483, Predicted ATPase (AAA+ superfamily) General function prediction only 85858389 Common - mu-like prophage Flumu protein gp29 SYN_02303 28 COG4383 COG4383, Mu-like prophage protein gp29 Function unknown 85860591 Common - transposase SYN_02987 84 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 85859175 Common - flagellar hook protein SYN_02839 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 85858242 Common - dTDP-glucose 4,6-dehydratase SYN_01130 235 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 85859927 Common - Na+ driven multidrug efflux pump SYN_00672 130 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 85860011 Common - ABC transporter ATP-binding protein SYN_00745 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 85859534 Nonpathogen - hypothetical cytosolic protein SYN_01876 1 None None None 85860919 Common - response regulator receiver domain and a sigma factor phosphatase domain SYN_00230 225 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 85859298 Nonpathogen - hypothetical cytosolic protein SYN_03221 3 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 85859920 Common - lipoprotein SYN_00666 67 COG3040 Blc, Bacterial lipocalin Cell envelope biogenesis, outer membrane 85857907 Nonpathogen - hypothetical cytosolic protein SYN_03232 1 None None None 85857921 Common - tRNA-specific adenosine deaminase SYN_00164 219 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 85860970 Nonpathogen - hypothetical cytosolic protein SYN_02095 1 None None None 85858824 Common - pentaglycine interpeptide bridge formation protein SYN_01477 30 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 85859065 Common - phosphomannomutase SYN_00938 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 85859640 Common - signal peptidase II (PSP1) -like protein SYN_00559 58 COG1774 COG1774, Uncharacterized homolog of PSP1 Function unknown 85859802 Common - tRNA pseudouridine synthase A SYN_01395 232 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 85859029 Common - response regulator CheY-like receiver domain SYN_00974 208 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 85858116 Common - cell division protein SYN_01274 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 85858528 Common - UDP-N-acetylenolpyruvoylglucosamine reductase SYN_01748 201 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 85857888 Common - alcohol dehydrogenase, class IV SYN_00021 147 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 85858111 Nonpathogen - hypothetical membrane protein SYN_01270 1 None None None 85858765 Common - hypothetical cytosolic protein SYN_02735 17 COG4683 COG4683, Uncharacterized protein conserved in bacteria Function unknown 85859544 Nonpathogen - metal dependent phosphohydrolases SYN_01887 3 None None None 85859679 Common - hypothetical cytosolic protein SYN_02999 123 COG0432 COG0432, Uncharacterized conserved protein Function unknown 85861006 Nonpathogen - hypothetical cytosolic protein SYN_02060 1 None None None 85859866 Common - glutaconyl-CoA decarboxylase A subunit SYN_00481 143 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 85860469 Common - ABC-type polysaccharide/polyol phosphate transport protein, ATPase component SYN_02656 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 85860694 Nonpathogen - hypothetical protein SYN_02428 1 COG1633 COG1633, Uncharacterized conserved protein Function unknown 85860891 Common - nif-specific regulatory protein with sigma 54 interaction domain SYN_01633 174 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 85857916 Common dapF diaminopimelate epimerase SYN_00169 203 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 85858380 Nonpathogen - hypothetical cytosolic protein SYN_02310 1 None None None 85858437 Common - hypothetical cytosolic protein SYN_02253 6 None None None 85859182 Common - flagellar biosynthetic protein SYN_02833 124 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 85858985 Common - 60 kDa inner membrane protein SYN_01014 212 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 85860344 Nonpathogen - hypothetical cytosolic protein SYN_00860 1 None None None 85859541 Common - soluble lytic murein transglycosylase SYN_01884 39 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 85860922 Common - hypothetical cytosolic protein SYN_00227 7 COG2198 ArcB, FOG: HPt domain Signal transduction mechanisms 85860138 Nonpathogen - hypothetical membrane protein SYN_00799 1 None None None 85858793 Common - chaperone protein SYN_02711 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 85859379 Common - trigger factor, ppiase SYN_02784 216 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 85858707 Nonpathogen - hypothetical cytosolic protein SYN_00136 1 None None None 85860954 Common - prephenate dehydratase SYN_01299 214 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 85859884 Common - type I restriction-modification system restriction subunit SYN_00497 135 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 85859703 Common - acid phosphatase SYN_01984 184 COG0496 SurE, Predicted acid phosphatase General function prediction only 85859913 Common - hypothetical membrane protein SYN_00661 9 None None None 85858404 Common - mu-like prophage tail protein gpP SYN_02288 18 COG4379 COG4379, Mu-like prophage tail protein gpP General function prediction only 85858719 Common - tolA protein SYN_00187 17 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 85859842 Common - general secretion pathway protein E SYN_00458 215 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 85860168 Common - ribonuclease HII SYN_00771 208 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 85858901 Common - hypothetical cytosolic protein SYN_02114 27 None None None 85859011 Nonpathogen - hypothetical cytosolic protein SYN_03190 1 None None None 85859351 Common - hypothetical membrane protein SYN_03061 39 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 85859147 Common - ABC transporter system permease involved in Fe-S cluster assembly SYN_02867 186 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 85859582 Common - hypothetical membrane protein SYN_00106 94 COG0762 COG0762, Predicted integral membrane protein Function unknown 85860462 Nonpathogen - hypothetical cytosolic protein SYN_02663 1 None None None 85858083 Common - Na+-translocating decarboxylase, beta subunit SYN_01434 56 COG1883 OadB, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit Energy production and conversion 85858556 Common - Fe-S oxidoreductase SYN_01355 60 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 85859140 Common - flp pilus assembly protein SYN_01491 54 COG3745 CpaB, Flp pilus assembly protein CpaB Intracellular trafficking and secretion 85859551 Nonpathogen - hypothetical cytosolic protein SYN_03587 3 None None None 85860364 Common - indolepyruvate oxidoreductase subunit SYN_01197 91 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 85858712 Common - bacterial HflC protein SYN_00180 35 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 85859591 Common - hypothetical cytosolic protein SYN_03056 6 None None None 85858048 Nonpathogen - hypothetical cytosolic protein SYN_02567 3 None None None 85858148 Common rplW 50S ribosomal protein L23 SYN_00987 173 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 85859589 Common - acetyltransferase, GNAT family SYN_00100 108 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 85860093 Common - UDP-3-O-[3-hydroxymyristoyl] glucosamine SYN_01568 162 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 85858025 Common - transcription termination factor NusB SYN_02373 192 COG0781 NusB, Transcription termination factor Transcription 85860075 Common - general secretion pathway protein G SYN_01551 74 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 85859056 Common - organic solvent tolerance protein SYN_00947 58 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 85860487 Common - iron-sulphur-binding reductase SYN_02638 109 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 85859677 Nonpathogen - hypothetical membrane protein SYN_02997 1 None None None 85858042 Nonpathogen - hypothetical cytosolic protein SYN_02562 1 None None None 85857955 Nonpathogen - hypothetical membrane protein SYN_02206 7 None None None 85858249 Common - UDP-glucose 6-dehydrogenase SYN_01124 204 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 85859840 Nonpathogen - hypothetical membrane protein SYN_00456 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 85860371 Nonpathogen - hypothetical membrane protein SYN_01190 1 None None None 85860583 Common - hypothetical cytosolic protein SYN_02472 46 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 85858725 Common - polysaccharide deacetylase SYN_00193 66 COG2861 COG2861, Uncharacterized protein conserved in bacteria Function unknown 85860073 Common - general secretion pathway protein E SYN_01549 178 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 85859658 Common - shikimate kinase SYN_01935 201 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 85859902 Common - exported lipoprotein SYN_00648 37 COG4315 COG4315, Uncharacterized protein conserved in bacteria Function unknown 85860740 Common - molybdenum cofactor biosynthesis protein A SYN_00381 205 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 85858742 Nonpathogen - hypothetical cytosolic protein SYN_02757 1 None None None 85858441 Common - hypothetical protein SYN_02249 31 COG1336 COG1336, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 85858671 Common - 6-o-methylguanine DNA methyltransferase SYN_02919 222 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 85859895 Nonpathogen - hypothetical cytosolic protein SYN_03089 1 None None None 85859492 Common - hesA/moeB/thiF type protein SYN_01833 52 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 85859932 Common - tetratricopeptide repeat family protein SYN_00677 85 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 85860308 Nonpathogen - hypothetical cytosolic protein SYN_01230 1 None None None 85859899 Nonpathogen - hypothetical cytosolic protein SYN_00645 1 None None None 85861008 Common - 4Fe-4S binding protein SYN_02058 72 COG0348 NapH, Polyferredoxin Energy production and conversion 85858972 Common - rhomboid family protein SYN_01026 110 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 85860066 Nonpathogen - hypothetical cytosolic protein SYN_01543 1 None None None 85860649 Common - glycosyltransferase involved in cell wall biogenesis SYN_00868 21 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 85860552 Common - hydroxyethylthiazole kinase SYN_00303 77 COG2145 ThiM, Hydroxyethylthiazole kinase, sugar kinase family Coenzyme metabolism 85858354 Common - transposase SYN_03036 64 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 85860632 Common - cysteine desulfurase / selenocysteine lyase SYN_01071 238 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 85858640 Nonpathogen - hypothetical cytosolic protein SYN_01755 1 None None None 85860109 Common - hypothetical cytosolic protein SYN_00828 3 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 85860656 Common - L-lysine 2,3-aminomutase SYN_02634 127 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 85859026 Nonpathogen - hypothetical cytosolic protein SYN_00976 1 None None None 85858379 Nonpathogen - hypothetical cytosolic protein SYN_03375 1 None None None 85860315 Nonpathogen - hypothetical cytosolic protein SYN_01239 20 COG1980 COG1980, Archaeal fructose 1,6-bisphosphatase Carbohydrate transport and metabolism 85858006 Common - tungsten transporter ATP binding protein SYN_00839 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 85860841 Common - pyridoxine biosynthesis amidotransferase SYN_01686 85 COG0311 PDX2, Predicted glutamine amidotransferase involved in pyridoxine biosynthesis Coenzyme metabolism 85858192 Nonpathogen - hypothetical cytosolic protein SYN_02033 1 None None None 85858800 Common - cell division inhibitor SYN_02705 142 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 85860595 Common - copper chaperone copZ SYN_01289 33 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 85858424 Common - delta-aminolevulinic acid dehydratase SYN_02267 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 85860781 Common - predicted permease SYN_00339 52 COG0701 COG0701, Predicted permeases General function prediction only 85860156 Nonpathogen - hypothetical cytosolic protein SYN_03722 1 None None None 85857984 Nonpathogen - hypothetical cytosolic protein SYN_00627 1 None None None 85858123 Common - orotidine 5'-phosphate decarboxylase SYN_01281 165 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 85859422 Nonpathogen - hypothetical cytosolic protein SYN_01038 2 None None None 85860195 Common - GDP-L-fucose synthase SYN_00585 229 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 85860217 Common - excinuclease ABC subunit B SYN_00609 229 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 85859452 Nonpathogen - hypothetical cytosolic protein SYN_00900 1 None None None 85858067 Common - acyl-CoA dehydrogenase, short-chain specific SYN_02587 164 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 85858160 Common rpsN 30S ribosomal protein S14 SYN_03315 212 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 85860532 Common - selenocysteine synthase SYN_01801 75 COG1921 SelA, Selenocysteine synthase [seryl-tRNASer selenium transferase] Amino acid transport and metabolism 85858415 Common - precorrin-2 dehydrogenase / Sirohydrochlorin ferrochelatase SYN_02276 158 COG1648 CysG, Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) Coenzyme metabolism 85858229 Nonpathogen - hypothetical cytosolic protein SYN_01143 4 None None None 85860226 Common - php domain containing protein (trph) SYN_00619 123 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 85858780 Common - sensory box/GGDEF family protein SYN_02722 190 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 85858322 Common - aldehyde dehydrogenase (ferredoxin) SYN_03032 57 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 85857939 Nonpathogen - hypothetical membrane protein SYN_00146 4 None None None 85859188 Nonpathogen - flagellar biosynthesis protein SYN_02826 1 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 85858869 Nonpathogen - hypothetical cytosolic protein SYN_03479 13 None None None 85858427 Common - UDP-sugar diphosphatase / 5'-nucleotidase SYN_02264 143 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 85860351 Common - periplasmic component of efflux system SYN_00852 170 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 85860812 Common - sec-independent protein translocase protein SYN_00305 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 85859924 Nonpathogen - hypothetical transport protein SYN_00669 2 None None None 85860607 Nonpathogen - hypothetical cytosolic protein SYN_01047 1 None None None 85857995 Nonpathogen - hypothetical cytosolic protein SYN_03239 1 None None None 85860021 Common - hypothetical membrane protein SYN_00754 21 COG2314 XynA, Predicted membrane protein Function unknown 85858634 Common - response regulator with a HTH DNA-binding domain SYN_01953 224 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 85857932 Common - NADH:ubiquinone oxidoreductase 24 kD subunit NuoE SYN_00153 156 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 85859002 Common - mannose-6-phosphate isomerase SYN_00111 18 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 85860387 Common - hypothetical cytosolic protein SYN_01174 47 COG2331 COG2331, Uncharacterized protein conserved in bacteria Function unknown 85860715 Nonpathogen - hypothetical cytosolic protein SYN_02407 1 None None None 85859107 Common - phosphoglucomutase SYN_01343 219 COG0033 Pgm, Phosphoglucomutase Carbohydrate transport and metabolism 85858265 Common - glycosyltransferase SYN_01108 126 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 85859876 Nonpathogen - hypothetical cytosolic protein SYN_00490 1 None None None 85859432 Common - uridylate kinase SYN_00920 234 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 85860814 Nonpathogen - hypothetical cytosolic protein SYN_03070 1 None None None 85860479 Common - hypothetical cytosolic protein SYN_02646 15 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 85860551 Common - thiol:disulfide interchange protein SYN_03114 49 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 85858862 Common - transposase SYN_01329 76 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 85860886 Common - di- and tricarboxylate transporters SYN_01639 49 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 85857865 Common - succinyl-CoA synthetase beta chain SYN_03227 208 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 85858702 Common - glycosyltransferase SYN_00131 59 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 85860214 Common - glutamate synthase (NADPH) SYN_00606 220 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 85860006 Common - histone deacetylase family protein SYN_00740 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 85858624 Nonpathogen - hypothetical cytosolic protein SYN_03434 1 None None None 85859158 Common - RNA pseudouridylate synthase S4 domain SYN_02856 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 85859413 Common - hypothetical cytosolic protein SYN_02933 113 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 85858794 Nonpathogen - hypothetical cytosolic protein SYN_03469 1 None None None 85858619 Nonpathogen - hypothetical membrane protein SYN_03138 1 None None None 85859726 Common - clpB protein SYN_02525 218 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 85860557 Common - glycogen phosphorylase SYN_00298 150 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 85860878 Common - NADH-quinone oxidoreductase chain E SYN_01647 157 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 85859226 Common - hypothetical cytosolic protein SYN_01388 9 None None None 85858938 Common - GTPase SYN_01372 220 COG1160 COG1160, Predicted GTPases General function prediction only 85859393 Nonpathogen - hypothetical membrane protein SYN_03143 1 None None None 85859909 Common - butyrate kinase SYN_03090 143 COG3426 COG3426, Butyrate kinase Energy production and conversion 85859669 Common - anthranilate synthase component II SYN_01946 239 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 85858366 Nonpathogen - hypothetical cytosolic protein SYN_03367 2 None None None 85860788 Nonpathogen - hypothetical membrane protein SYN_00332 1 None None None 85860726 Common - catalase SYN_02396 126 COG0753 KatE, Catalase Inorganic ion transport and metabolism 85859863 Common - carbon-nitrogen hydrolase family protein SYN_00478 200 COG0388 COG0388, Predicted amidohydrolase General function prediction only 85858284 Common - n-(5'-phosphoribosyl)anthranilate isomerase SYN_02592 160 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 85859233 Nonpathogen - hypothetical cytosolic protein SYN_01380 3 None None None 85859628 Common - exodeoxyribonuclease VII large subunit SYN_02459 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 85860324 Nonpathogen - hypothetical cytosolic protein SYN_01249 1 None None None 85859287 Nonpathogen - hypothetical cytosolic protein SYN_02169 1 None None None 85859313 Common - hypothetical membrane protein SYN_02542 14 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 85859133 Common - flp pilus assembly protein SYN_01498 90 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 85860700 Nonpathogen - heterodisulfide reductase, subunit A SYN_02422 31 COG1148 HdrA, Heterodisulfide reductase, subunit A and related polyferredoxins Energy production and conversion 85859478 Common - hypothetical cytosolic protein SYN_01818 13 None None None 85858465 Common - integrase family protein SYN_02227 205 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 85860692 Common - ATP-dependent RNA helicase SYN_02430 240 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 85860441 Common - hypothetical cytosolic protein SYN_02684 25 None None None 85859578 Common - putative alpha-isopropylmalate/homocitrate synthase family transferase SYN_02194 213 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 85860431 Common - hypothetical membrane protein SYN_03766 19 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 85860047 Common - queuine tRNA-ribosyltransferase SYN_00038 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 85860436 Common - UDP-N-acetylglucosamine 4,6-dehydratase / UDP-4-dehydro-6-deoxy-2-acetamido-D-glucose 4-reductase SYN_02689 221 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 85858548 Nonpathogen - DnaJ domain protein SYN_01346 1 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 85860279 Nonpathogen - hypothetical cytosolic protein SYN_02519 1 None None None 85859445 Common - amidophosphoribosyltransferase SYN_00907 227 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 85859856 Common - arabinose-5-phosphate isomerase SYN_00471 152 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 85859403 Nonpathogen - hypothetical protein SYN_02185 3 None None None 85859773 Common - methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase SYN_02873 223 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 85858651 Common - 4-hydroxybenzoate--CoA ligase / benzoate--CoA ligase SYN_02898 223 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 85860016 Nonpathogen - hypothetical cytosolic protein SYN_03107 1 None None None 85860144 Common - phosphatidylserine/phosphatidylglycerophosphate related protein SYN_00794 57 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 85860267 Nonpathogen - hypothetical protein SYN_03739 1 None None None 85859695 Nonpathogen - hypothetical cytosolic protein SYN_01992 1 None None None 85859745 Common - monofunctional biosynthetic peptidoglycan transglycosylase SYN_01407 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 85858615 Nonpathogen - hypothetical cytosolic protein SYN_02942 1 None None None 85860026 Common - gatB/yqey domain protein SYN_00759 151 COG1610 COG1610, Uncharacterized conserved protein Function unknown 85860993 Common - mutT/nudix family protein SYN_02072 12 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 85858628 Common - xaa-pro aminopeptidase SYN_03148 139 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 85858733 Nonpathogen - hypothetical cytosolic protein SYN_02483 1 None None None 85859253 Common - ABC-type molybdate transport system, ATPase component SYN_00271 249 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 85859771 Common - gamma-carboxymuconolactone decarboxylase SYN_02871 66 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 85859460 Common - membrane bound protein mediates protein-protein interactions SYN_00893 9 COG2976 COG2976, Uncharacterized protein conserved in bacteria Function unknown 85860516 Common - SSU ribosomal protein S15P SYN_01782 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 85858593 Nonpathogen - hypothetical cytosolic protein SYN_02964 1 None None None 85859407 Nonpathogen - hypothetical cytosolic protein SYN_02938 1 None None None 85858289 Nonpathogen - hypothetical cytosolic protein SYN_02598 1 None None None 85858167 Common secY preprotein translocase subunit SecY SYN_01595 242 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 85860848 Common - 3-oxoacyl- reductase SYN_01680 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 85859248 Nonpathogen - hypothetical cytosolic protein SYN_00276 5 None None None 85858924 Common - formate dehydrogenase SYN_02138 192 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 85859826 Common - thiamin-phosphate pyrophosphorylase SYN_00442 198 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 85860755 Common - sulfate transport system permease protein SYN_00366 206 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 85858212 Nonpathogen - hypothetical cytosolic protein SYN_01160 2 None None None 85858685 Common - signal transduction histidine kinase SYN_00882 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 85859166 Common - dihydroorotate dehydrogenase electron transfer subunit SYN_02848 83 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 85860944 Common - phosphate/sulphate permease SYN_00206 87 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 85860515 Nonpathogen - hypothetical cytosolic protein SYN_01781 1 None None None 85858696 Common - pili retraction protein SYN_00125 203 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 85858899 Common - acetyl-CoA synthetase beta subunit SYN_02112 145 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 85858267 Common - glycosyltransferase SYN_01106 201 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 85860033 Nonpathogen - ATP phosphoribosyltransferase SYN_03698 14 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 85860986 Common - hypothetical cytosolic protein SYN_03854 6 None None None 85860589 Common - ATP-dependent RNA helicase SYN_02478 74 COG1203 COG1203, Predicted helicases General function prediction only 85860802 Common - hydrolase SYN_00315 31 COG2316 COG2316, Predicted hydrolase (HD superfamily) General function prediction only 85858089 Common - prolipoprotein diacylglyceryl transferase SYN_01440 209 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 85859832 Common - general secretion pathway protein D SYN_00448 143 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 85858060 Nonpathogen - hypothetical cytosolic protein SYN_03293 1 None None None 85859481 Nonpathogen - hypothetical cytosolic protein SYN_01821 1 None None None 85860508 Common - pili assembly protein SYN_01774 42 COG3167 PilO, Tfp pilus assembly protein PilO Cell motility and secretion / Intracellular trafficking and secretion 85858219 Nonpathogen - hypothetical cytosolic protein SYN_01153 4 None None None 85858273 Common - coenzyme F390 Synthetase / phenylacetate-coenzyme A ligase SYN_01100 103 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 85859000 Common - chaperone protein dnaJ SYN_00110 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 85860873 Common - xaa-pro aminopeptidase SYN_01652 173 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 85858393 Common - hypothetical cytosolic protein SYN_03379 7 None None None 85858386 Common - hypothetical cytosolic protein SYN_02306 10 None None None 85859260 Nonpathogen - hypothetical cytosolic protein SYN_03217 3 None None None 85858584 Common - hypothetical protein SYN_02974 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 85860731 Common - glycosyltransferase involved in cell wall biogenesis SYN_02391 194 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 85858889 Common - hypothetical protein SYN_00394 21 None None None 85860776 Common - hypothetical cytosolic protein SYN_00344 11 None None None 85859904 Nonpathogen - hypothetical cytosolic protein SYN_00650 1 None None None 85858206 Common - type II restriction enzyme, methylase SYN_00524 87 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 85859127 Nonpathogen - hypothetical membrane protein SYN_01504 1 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 85857949 Common - zn-dependent protease with chaperone function SYN_02199 127 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 85860285 Common - magnesium and cobalt efflux protein SYN_01208 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 85860392 Common - predicted acetyltransferase SYN_01169 196 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 85860893 Nonpathogen - glutamate synthase (NADPH) SYN_01631 10 COG0067 GltB, Glutamate synthase domain 1 Amino acid transport and metabolism 85858035 Common - LSU ribosomal protein L32P SYN_02363 71 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 85858803 Common tnaA tryptophanase SYN_01455 44 COG3033 TnaA, Tryptophanase Amino acid transport and metabolism 85858542 Common - long-chain-fatty-acid--CoA ligase SYN_03128 218 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 85858071 Common - tonB periplasmic protein SYN_01422 47 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 85858094 Common - divalent cation tolerance protein SYN_01445 105 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 85859653 Nonpathogen - hypothetical cytosolic protein SYN_01930 1 None None None 85858078 Nonpathogen - hypothetical cytosolic protein SYN_01429 1 None None None 85857852 Nonpathogen - hypothetical cytosolic protein SYN_02045 2 None None None 85858295 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B SYN_02604 213 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 85859676 Nonpathogen - hypothetical cytosolic protein SYN_02996 1 None None None 85858551 Common - hypothetical membrane protein SYN_01349 70 COG2119 COG2119, Predicted membrane protein Function unknown 85858373 Nonpathogen - hypothetical membrane protein SYN_03371 1 None None None 85860051 Nonpathogen - hypothetical membrane protein SYN_01526 2 COG2839 COG2839, Uncharacterized protein conserved in bacteria Function unknown 85857873 Common - transcriptional regulator with a HTH domain SYN_00007 67 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 85860978 Nonpathogen - hypothetical cytosolic protein SYN_02087 6 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 85860972 Common - hypothetical cytosolic protein SYN_02093 25 COG1102 Cmk, Cytidylate kinase Nucleotide transport and metabolism 85859039 Common - protein-glutamate methylesterase CheB SYN_00964 201 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 85859348 Common - ABC transporter ATP-binding protein SYN_00283 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 85859995 Common - NAD(FAD)-utilizing dehydrogenases SYN_00731 142 COG2081 COG2081, Predicted flavoproteins General function prediction only 85860855 Nonpathogen - hypothetical cytosolic protein SYN_01674 1 None None None 85858501 Common - phenylalanyl-tRNA synthetase alpha chain SYN_01721 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 85860399 Common - zinc transporter SYN_01162 54 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 85859306 Common - ferridoxin SYN_02549 62 COG2768 COG2768, Uncharacterized Fe-S center protein General function prediction only 85859138 Nonpathogen - hypothetical protein SYN_01493 4 None None None 85860626 Common - hypothetical protein SYN_01065 24 COG4254 COG4254, Uncharacterized protein conserved in bacteria Function unknown 85859284 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase SYN_02166 208 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 85857965 Nonpathogen - hypothetical protein SYN_02216 3 COG3678 CpxP, P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein Intracellular trafficking and secretion / Cell motility and secretio / Signal transduction mechanisms / Inorganic ion transport and metabolism 85859094 Common - signal peptide peptidase SYN_03198 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 85859532 Common - pilus assembly protein SYN_01874 24 None None None 85859778 Nonpathogen - thiol-specific antioxidant protein SYN_03083 1 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 85860994 Common - swf/snf family helicase SYN_02071 139 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 85858056 Common - hypothetical membrane protein SYN_02575 42 COG4420 COG4420, Predicted membrane protein Function unknown 85859637 Common - thymidylate kinase SYN_03606 223 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 85858051 Common - sensory box ggdef family protein SYN_02570 183 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 85860544 Common - 4Fe-4S ferredoxin, iron-sulfur binding SYN_03784 37 COG2006 COG2006, Uncharacterized conserved protein Function unknown 85860184 Common - cAMP-dependent transcriptional regulator SYN_00574 151 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 85860186 Common - dTDP-4-dehydrorhamnose 3,5-epimerase SYN_00576 41 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 85860852 Common - formate dehydrogenase activity protein SYN_01676 137 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 85858826 Common - adenylate cyclase SYN_01481 92 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 85857899 Common - cell wall degradation protein SYN_00032 75 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 85858999 Common - methyltransferase SYN_00109 32 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 85859693 Common - response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains SYN_01093 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 85858235 Common - pectate lyase SYN_01137 19 COG3866 PelB, Pectate lyase Carbohydrate transport and metabolism 85858776 Common - hypothetical protein SYN_02727 5 None None None 85858739 Common - Mg(2+) transport ATPase, P-type SYN_02760 230 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 85859396 Common - uracil DNA glycosylase superfamily protein SYN_02178 157 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 85858307 Common - ferridoxin SYN_00247 46 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 85858576 Common - hydrolase SYN_02979 77 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 85859988 Nonpathogen - hypothetical protein SYN_00724 1 None None None 85860567 Common - endonuclease III N SYN_00287 238 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 85859864 Common - biotin carboxyl carrier protein of glutaconyl-CoA decarboxylase SYN_00479 189 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 85858232 Common - acetyltransferase SYN_01140 100 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 85858279 Common - periplasmic protein involved in polysaccharide export SYN_01205 122 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 85859767 Nonpathogen - hypothetical membrane protein SYN_01303 1 COG4980 GvpP, Gas vesicle protein General function prediction only 85859199 Common flgI flagellar basal body P-ring protein SYN_02816 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 85860250 Nonpathogen - hypothetical cytosolic protein SYN_02490 6 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 85858183 Common - cysteinyl-tRNA synthetase SYN_03026 242 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 85858339 Nonpathogen - putative diacylglycerolkinase SYN_02353 4 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 85858962 Common - predicted ATPase protein with chaperone activity SYN_00569 28 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 85860975 Common - ADP-ribose pyrophosphatase SYN_02090 171 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 85858602 Nonpathogen - hypothetical cytosolic protein SYN_03427 1 None None None 85860350 Common - ABC transporter ATP-binding commponent SYN_00853 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 85857918 Common - translation-associated GTPase SYN_00167 216 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 85858631 Nonpathogen - pyruvoyl-dependent arginine decarboxylase SYN_01577 28 COG1945 COG1945, Uncharacterized conserved protein Function unknown 85859685 Common - spore maturation protein B SYN_01086 39 COG0700 SpmB, Uncharacterized membrane protein Function unknown 85859944 Nonpathogen - hypothetical cytosolic protein SYN_03098 1 None None None 85858945 Nonpathogen - pyruvoyl-dependent arginine decarboxylase SYN_01365 29 COG1945 COG1945, Uncharacterized conserved protein Function unknown 85860738 Nonpathogen - hypothetical cytosolic protein SYN_03069 1 None None None 85859207 Common - FlaG flagellar related protein SYN_02808 5 COG1334 FlaG, Uncharacterized flagellar protein FlaG Cell motility and secretion 85859235 Common - pyridoxal phosphate biosynthetic protein PdxJ SYN_01378 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 85860124 Nonpathogen - hypothetical membrane protein SYN_00813 2 None None None 85858680 Common - branched-chain amino acid aminotransferase SYN_03154 103 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 85859219 Nonpathogen - hypothetical cytosolic protein SYN_03208 3 None None None 85859602 Nonpathogen - hypothetical cytosolic protein SYN_03600 1 None None None 85858463 Common - DNA damage inducible protein SYN_02229 35 COG3041 COG3041, Uncharacterized protein conserved in bacteria Function unknown 85860455 Common - UDP-N-acetylglucosamine 4,6-dehydratase / UDP-D-quinovosamine 4-dehydrogenase SYN_02670 220 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 85857905 Nonpathogen - hypothetical cytosolic protein SYN_03231 1 None None None 85858330 Common - cobalt-zinc-cadmium resistance protein SYN_03034 123 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 85857974 Common - phosphate uptake ABC transporter SYN_03279 226 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 85858766 Nonpathogen - hypothetical cytosolic protein SYN_03461 1 None None None 85858605 Common - pyruvate kinase SYN_02952 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 85859518 Nonpathogen - hypothetical membrane protein SYN_01860 2 None None None 85860575 Nonpathogen - hypothetical cytosolic protein SYN_02463 5 None None None 85858598 Common - phosphoglucosamine mutase SYN_02959 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 85859951 Nonpathogen - hypothetical protein SYN_00690 1 None None None 85860425 Common - ribonuclease D SYN_02700 118 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 85859336 Common - ABC-type phosphate transport system, ATPase component SYN_00059 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 85858508 Common - phosphocarrier protein HPr SYN_01728 147 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 85860058 Common - Mg/Co/Ni transporter SYN_01534 170 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 85859150 Nonpathogen - hypothetical cytosolic protein SYN_03530 1 None None None 85858787 Nonpathogen - hypothetical cytosolic protein SYN_02716 1 None None None 85858240 Nonpathogen - hypothetical membrane protein SYN_01132 1 None None None 85860095 Common - outer membrane protein SYN_00921 163 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 85859070 Common - hydrolase, haloacid dehalogenase-like family SYN_00933 56 COG0546 Gph, Predicted phosphatases General function prediction only 85860490 Common - acetyl-CoA synthetase SYN_02635 213 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 85858011 Nonpathogen - hypothetical cytosolic protein SYN_03242 1 None None None 85860158 Nonpathogen - hypothetical protein SYN_00781 5 None None None 85860330 Nonpathogen - hypothetical cytosolic protein SYN_01254 1 None None None 85858954 Common - nucleotidyltransferase/DNA polymerase protein SYN_00561 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 85859607 Nonpathogen - hypothetical cytosolic protein SYN_02010 1 None None None 85858541 Common - ATP-dependent DNA helicase SYN_00427 99 COG4581 COG4581, Superfamily II RNA helicase DNA replication, recombination, and repair 85858836 Nonpathogen - hypothetical membrane protein SYN_00407 3 None None None 85858324 Nonpathogen - hypothetical protein SYN_03351 1 None None None 85858020 Common - ATPase clp protease ATP binding subunit SYN_02378 218 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 85860385 Common - hypothetical cytosolic protein SYN_01176 22 COG2014 COG2014, Uncharacterized conserved protein Function unknown 85858516 Common - cell division protein SYN_01736 132 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 85858987 Common - ribonuclease P protein component SYN_01012 110 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 85860576 Nonpathogen - hypothetical cytosolic protein SYN_02464 4 None None None 85858789 Common - signal transduction histidine kinase involved in nitrogen metabolism regulation SYN_02714 222 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 85859855 Common - rubrerythrin SYN_00469 79 COG1592 COG1592, Rubrerythrin Energy production and conversion 85858931 Common - N-acetylmuramoyl-L-alanine amidase SYN_02145 175 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 85858118 Nonpathogen - hypothetical cytosolic protein SYN_01276 1 None None None 85858397 Nonpathogen - hypothetical cytosolic protein SYN_02295 1 None None None 85859645 Nonpathogen - hypothetical protein SYN_03614 1 None None None 85860326 Common - iscU family protein SYN_03754 18 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 85860342 Nonpathogen - hypothetical cytosolic protein SYN_03758 2 None None None 85859181 Common - flagellar biosynthetic protein SYN_02834 62 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 85859387 Common - predicted metal-dependent hydrolase SYN_02792 92 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 85860013 Common - hypothetical protein SYN_00747 51 COG5621 COG5621, Predicted secreted hydrolase General function prediction only 85859153 Common - DNA repair protein recN SYN_02862 197 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 85860373 Common - dinitrogenase iron-molybdenum cofactor protein SYN_01188 29 COG1433 COG1433, Uncharacterized conserved protein Function unknown 85859040 Common - chemotaxis protein SYN_00963 157 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 85860028 Common - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase SYN_00761 216 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 85858897 Common - outer membrane OmpA family protein SYN_02110 173 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 85858171 Common - 30S ribosomal protein S11 SYN_01599 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 85858757 Nonpathogen - hypothetical cytosolic protein SYN_02742 6 None None None 85858120 Common - hypothetical protein SYN_01278 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 85859823 Common thiH thiamine biosynthesis protein ThiH SYN_00439 57 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 85860753 Common - benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB SYN_00368 36 COG1775 HgdB, Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB Amino acid transport and metabolism 85860822 Nonpathogen - hypothetical cytosolic protein SYN_01707 1 None None None 85859067 Nonpathogen - hypothetical cytosolic protein SYN_00936 1 None None None 85858661 Common - ATP-dependent DNA helicase SYN_02908 177 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 85857960 Common - ammonium transporter SYN_02211 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 85860791 Common - von Willebrand factor type A domain protein SYN_00328 42 COG3552 CoxE, Protein containing von Willebrand factor type A (vWA) domain General function prediction only 85859539 Nonpathogen - hypothetical cytosolic protein SYN_01882 1 None None None 85860677 Common - hypothetical cytosolic protein SYN_00236 39 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 85858565 Nonpathogen - hypothetical cytosolic protein SYN_02444 1 None None None 85858097 Common - thymidylate kinase SYN_01448 105 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 85859845 Nonpathogen - hypothetical cytosolic protein SYN_03085 1 None None None 85859149 Nonpathogen - hypothetical cytosolic protein SYN_02865 2 None None None 85860966 Common - hypothetical membrane protein SYN_02099 20 None None None 85860292 Common - 4-aminobutyrate aminotransferase SYN_01215 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 85860933 Common - ABC-type Fe3+-siderophore transport system, permease component SYN_00217 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 85859361 Common - hypothetical protein SYN_01965 197 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 85860151 Common - branched-chain amino acid transport system permease protein SYN_00787 158 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 85859131 Common - tetratricopeptide repeat family protein SYN_01500 63 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 85860162 Nonpathogen - hypothetical cytosolic protein SYN_00777 1 None None None 85858114 Nonpathogen - hypothetical cytosolic protein SYN_01272 1 None None None 85858892 Common - hypothetical cytosolic protein SYN_00396 19 COG1359 COG1359, Uncharacterized conserved protein Function unknown 85859922 Common - hypothetical protein SYN_00668 4 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 85858493 Nonpathogen - hypothetical cytosolic protein SYN_00528 1 None None None 85860924 Common - cobalt-zinc-cadmium resistance protein SYN_00225 218 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 85860961 Common - F0F1 ATP synthase subunit alpha SYN_02104 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 85858133 Common - transcription antitermination protein SYN_00070 215 COG0250 NusG, Transcription antiterminator Transcription 85859642 Nonpathogen - aldolase SYN_00557 4 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 85859060 Common - nitrogen regulatory IIA protein SYN_00943 136 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 85860686 Common - transposase SYN_00245 83 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 85858210 Common - trypsin-like serine protease SYN_00527 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 85860061 Common - glycyl-tRNA synthetase beta chain SYN_01537 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 85859785 Common - pantothenate kinase SYN_02883 135 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 85859310 Common - phosphate transport regulator SYN_02545 76 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 85859465 Common - phosphoribosylaminoimidazole synthetase SYN_00889 233 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 85860255 Common - cytidylate kinase SYN_02496 13 COG1102 Cmk, Cytidylate kinase Nucleotide transport and metabolism 85858178 Common - organic solvent tolerance protein SYN_01607 128 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 85858176 Common - metallo-beta-lactamase superfamily protein SYN_01605 43 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 85859783 Nonpathogen - hypothetical cytosolic protein SYN_02881 1 None None None 85858484 Common - beta-propeller domain of methanol dehydrogenase type protein SYN_00537 88 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 85859962 Nonpathogen - hypothetical membrane protein SYN_00701 1 None None None 85860459 Common - asparagine synthetase (glutamine-hydrolyzing) SYN_02666 151 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 85858539 Common - exodeoxyribonuclease III SYN_00429 196 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 85857859 Common - peptidyl-prolyl cis-trans isomerase SYN_02039 200 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 85859522 Common - hypothetical protein SYN_01864 4 None None None 85858499 Common - LSU ribosomal protein L35P SYN_01719 91 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 85860846 Common - hypothetical cytosolic protein SYN_01682 35 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 85859794 Common - zn-dependent hydrolase SYN_02892 6 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 85860278 Nonpathogen - hypothetical cytosolic protein SYN_02518 1 None None None 85859329 Common - predicted ATPase with chaperone activity SYN_00051 27 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 85860362 Nonpathogen - hypothetical cytosolic protein SYN_01199 1 None None None 85857885 Nonpathogen - hypothetical cytosolic protein SYN_00018 1 None None None 85858566 Common - sua5/yciO/yrdC/ywlC family protein SYN_02443 238 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 85859599 Nonpathogen - hypothetical cytosolic protein SYN_02017 11 COG2164 COG2164, Uncharacterized conserved protein Function unknown 85860331 Common - o-acetyl-L-homoserine sulfhydrolase / O-acetyl-L-serine sulfhydrolase SYN_01255 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 85859320 Common - aspartyl-tRNA synthetase SYN_02535 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 85860203 Common - hypA family hydrogenase nickel incorporation protein SYN_00595 99 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 85859037 Nonpathogen - hypothetical cytosolic protein SYN_00966 2 None None None 85860902 Nonpathogen - hypothetical protein SYN_01621 4 None None None 85859173 Common - flagellar hook-length control protein SYN_02841 12 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 85860901 Nonpathogen - amidohydrolase SYN_01623 9 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 85858864 Common - transposase SYN_03174 84 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 85858913 Common - cysteine desulfurase SYN_02126 240 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 85860125 Nonpathogen - hypothetical cytosolic protein SYN_03715 1 None None None 85860023 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase SYN_00756 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 85860718 Common - outer membrane protein (DUF490) SYN_02404 109 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 85860526 Common - peptide release factor-glutamine N5-methyltransferase SYN_01794 229 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 85860337 Common - rrf2 family protein SYN_03008 181 COG1959 COG1959, Predicted transcriptional regulator Transcription 85860909 Nonpathogen - hypothetical cytosolic protein SYN_01614 1 None None None 85860647 Common - hypothetical protein SYN_00866 23 COG2930 COG2930, Uncharacterized conserved protein Function unknown 85858451 Nonpathogen - hypothetical cytosolic protein SYN_03399 1 None None None 85860036 Common - acetyl-CoA synthetase beta subunit SYN_00049 151 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 85858911 Common - ferric-chelate reductase / Rubredoxin SYN_02123 149 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 85858843 Common - cell division inhibitor SYN_03476 65 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 85860043 Common - sir2 family protein SYN_00042 153 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 85860310 Nonpathogen - hypothetical cytosolic protein SYN_01232 1 None None None 85860916 Common - enoyl-CoA dehydratase, putative SYN_03076 180 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 85860089 Common - phospholipid-lipopolysaccharide ABC transporter SYN_01564 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 85859291 Common - oligopeptide transport ATP-binding protein SYN_02172 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 85860108 Common - glycosyltransferase involved in cell wall biogenesis SYN_00829 209 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 85860235 Nonpathogen - hypothetical membrane protein SYN_01585 1 None None None 85859569 Common - nuclease SYN_01912 6 COG3857 AddB, ATP-dependent nuclease, subunit B DNA replication, recombination, and repair 85859024 Common - methyl-accepting chemotaxis protein domain SYN_00978 48 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 85858559 Common - hypoxanthine-guanine phosphoribosyltransferase SYN_02450 150 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 85859016 Common - phage integrase family protein SYN_00121 60 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 85860635 Common - hypothetical protein SYN_01074 11 COG4254 COG4254, Uncharacterized protein conserved in bacteria Function unknown 85859777 Nonpathogen - thioredoxin peroxidase SYN_03642 3 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 85860131 Common - glycine reductase complex selenoprotein A SYN_00806 7 None None None 85860126 Common - metalloprotease, insulinase family SYN_00812 100 COG1026 COG1026, Predicted Zn-dependent peptidases, insulinase-like General function prediction only 85859563 Common - chaperone protein dnaJ SYN_01906 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 85860843 Common - imidazole glycerol phosphate synthase, cyclase subunit SYN_01684 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 85860512 Common - hypothetical cytosolic protein SYN_01778 34 COG1900 COG1900, Uncharacterized conserved protein Function unknown 85858318 Common - heterodisulfide reductase, subunit A SYN_00257 45 COG1148 HdrA, Heterodisulfide reductase, subunit A and related polyferredoxins Energy production and conversion 85860024 Common - RNA polymerase sigma factor SYN_00757 220 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 85859804 Nonpathogen - hypothetical cytosolic protein SYN_01397 1 None None None 85858562 Common - pyridine nucleotide-disulphide oxidoreductase family protein SYN_02447 220 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 85860938 Common - biotin-(acetyl-CoA carboxylase) ligase SYN_00211 203 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 85859538 Common - transcriptional regulator, Cro/CI family SYN_01881 6 COG5499 COG5499, Predicted transcription regulator containing HTH domain Transcription 85860821 Common - dihydroxy-acid dehydratase SYN_01708 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 85858469 Nonpathogen - hypothetical membrane protein SYN_00552 1 None None None 85859101 Common - dnaK suppressor protein SYN_01337 162 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 85860117 Common - mannosyltransferase SYN_00820 110 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 85858561 Common - zinc finger protein SYN_02448 14 COG3862 COG3862, Uncharacterized protein with conserved CXXC pairs Function unknown 85860161 Common - general secretion pathway protein A SYN_00778 73 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 85859833 Common - lytic transglycosylase -like protein SYN_00449 177 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 85860561 Nonpathogen - hypothetical membrane protein SYN_03789 1 None None None 85858820 Common - flagellum-specific ATP synthase SYN_01473 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 85858189 Common - colligrin SYN_02030 212 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 85860098 Common - lysyl-tRNA synthetase SYN_00924 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 85860179 Nonpathogen - hypothetical cytosolic protein SYN_03023 1 None None None 85860912 Common - glutathione-regulated potassium-efflux system protein SYN_01611 160 COG1226 Kch, Kef-type K+ transport systems, predicted NAD-binding component Inorganic ion transport and metabolism 85859467 Common - diphosphate--fructose-6-phosphate 1-phosphotransferase SYN_00887 161 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 85859168 Common - phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC SYN_02846 34 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 85859797 Nonpathogen - tetratricopeptide repeat domain containing protein SYN_02895 7 None None None 85861002 Common - outer membrane protein SYN_02063 36 COG3528 COG3528, Uncharacterized protein conserved in bacteria Function unknown 85859230 Common - rubredoxin SYN_01383 117 COG1773 COG1773, Rubredoxin Energy production and conversion 85858935 Nonpathogen - hypothetical cytosolic protein SYN_03501 1 None None None 85858866 Common - response regulator protein with GGDEF domain SYN_01324 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 85858758 Nonpathogen - hypothetical cytosolic protein SYN_03459 1 None None None 85858494 Common - putative periplasmic protein SYN_03043 4 COG4380 COG4380, Uncharacterized protein conserved in bacteria Function unknown 85860778 Common - transcriptional regulator, marR family SYN_00342 24 COG1846 MarR, Transcriptional regulators Transcription 85860502 Common - glycine cleavage system H protein SYN_01768 187 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 85860574 Common - hypothetical cytosolic protein SYN_03794 7 None None None 85858113 Nonpathogen - hypothetical cytosolic protein SYN_01271 1 None None None 85859294 Common - elongation factor G SYN_01574 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 85858470 Common - cell elongation specific D,D-transpeptidase SYN_00551 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 85860467 Common - glycosyltransferase SYN_02658 112 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 85859186 Common - flagellar synthesis regulator SYN_02828 219 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 85860112 Common - o-antigen export system permease protein SYN_00825 138 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 85858767 Nonpathogen - hypothetical cytosolic protein SYN_02734 2 None None None 85858817 Common - flagellar M-ring protein SYN_01470 126 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 85860183 Nonpathogen - pilin assembly protein SYN_01761 1 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 85860102 Common - myo-inositol-1(or 4)-monophosphatase SYN_00928 213 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 85858649 Common - 4-hydroxybenzoate--CoA ligase / benzoate--CoA ligase SYN_02896 223 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 85858132 Nonpathogen - protein translocase subunit SYN_00071 2 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 85859178 Common - flagellar motor switch protein SYN_02836 124 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 85859069 Common - acetyl-CoA CoA transferase / acetyltransferase SYN_00934 144 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 85859889 Common - hypothetical membrane protein SYN_00502 9 None None None 85860981 Common - multidrug resistance protein B SYN_02085 214 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 85859926 Nonpathogen - hypothetical cytosolic protein SYN_00671 1 None None None 85860784 Common - glutaredoxin SYN_00336 10 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 85859170 Common - pts system fructose IIA component SYN_02844 95 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 85858904 Nonpathogen - hypothetical cytosolic protein SYN_02117 1 None None None 85860926 Nonpathogen - hypothetical cytosolic protein SYN_00223 1 None None None 85859360 Common - hypothetical cytosolic protein SYN_01964 12 COG2921 COG2921, Uncharacterized conserved protein Function unknown 85858709 Common - pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit SYN_03161 19 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 85857912 Common - signal transduction histidine kinase with receiver domain SYN_00174 225 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 85860676 Common - hydroxylamine reductase SYN_02993 74 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 85860293 Common - potassium channel protein SYN_01216 154 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 85859224 Nonpathogen - hypothetical cytosolic protein SYN_03212 1 None None None 85859307 Nonpathogen - hypothetical cytosolic protein SYN_02548 1 None None None 85860931 Nonpathogen - hypothetical cytosolic protein SYN_00219 1 None None None 85858385 Common - hypothetical membrane protein SYN_02307 8 None None None 85859987 Common - transposase SYN_00723 69 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 85858157 Common - LSU ribosomal protein L14P SYN_03257 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 85858980 Common - ADP-ribose pyrophosphatase SYN_01018 168 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 85859161 Common cyaA adenylate cyclase SYN_02853 25 COG3072 CyaA, Adenylate cyclase Nucleotide transport and metabolism 85859546 Common - ATPase components of ABC transporters with duplicated ATPase domains SYN_01888 248 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 85858512 Nonpathogen - hypothetical cytosolic protein SYN_01731 1 None None None 85858847 Common - transposase SYN_03065 84 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 85858919 Common - hypothetical transcriptional regulatory protein SYN_02132 14 None None None 85861010 Common - degT/dnrJ/eryC1/strS aminotransferase family protein SYN_02056 193 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 85860730 Common - N-carbamoylputrescine amidase SYN_02392 207 COG0388 COG0388, Predicted amidohydrolase General function prediction only 85860358 Nonpathogen - hypothetical cytosolic protein SYN_03126 1 None None None 85858331 Nonpathogen - hypothetical cytosolic protein SYN_03035 1 None None None 85859246 Nonpathogen - hypothetical cytosolic protein SYN_00277 1 None None None 85860272 Nonpathogen - hypothetical cytosolic protein SYN_02512 1 None None None 85860347 Common - glycosyltransferase SYN_00856 111 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 85857902 Common - permease of the DMT superfamily SYN_00035 9 COG2510 COG2510, Predicted membrane protein Function unknown 85859575 Common - Selenocysteine-specific protein translation Elongation Factor SYN_02191 249 COG3276 SelB, Selenocysteine-specific translation elongation factor Translation, ribosomal structure and biogenesis 85859151 Common - hypothetical cytosolic protein SYN_02864 12 None None None 85859857 Nonpathogen - hypothetical protein SYN_00472 1 None None None 85858345 Nonpathogen - cytochrome b5-like heme/Steroid binding domain protein SYN_02347 12 COG4892 COG4892, Predicted heme/steroid binding protein General function prediction only 85858019 Common aat leucyl/phenylalanyl-tRNA--protein transferase SYN_02379 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 85859033 Common - chemotaxis protein methyltransferase SYN_00970 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 85858447 Nonpathogen - hypothetical cytosolic protein SYN_02243 1 None None None 85858172 Common - SSU ribosomal protein S4P SYN_01600 246 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 85858604 Common - diphosphate--fructose-6-phosphate 1-phosphotransferase SYN_02953 145 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 85860322 Nonpathogen - hypothetical membrane protein SYN_01247 2 None None None 85859062 Common - hypothetical protein SYN_00941 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 85859992 Nonpathogen - hypothetical cytosolic protein SYN_00728 1 None None None 85858535 Common - chemotaxis protein SYN_00433 126 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 85859438 Common - non-proteolytic protein peptidase M22 family, putative molecular chaperone SYN_00914 175 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 85860314 Nonpathogen - hypothetical cytosolic protein SYN_01238 1 None None None 85858358 Common - hypothetical membrane protein SYN_02333 6 None None None 85860422 Common - 5-methyltetrahydrofolate--homocysteine methyltransferase SYN_02703 181 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 85858927 Nonpathogen - pyridoxamine 5'-phosphate oxidase-related SYN_02141 9 None None None 85859675 Common - protease I SYN_02766 171 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 85860166 Common - ABC transporter permease protein SYN_00773 139 COG1511 COG1511, Predicted membrane protein Function unknown 85858091 Common - hypothetical membrane protein SYN_01442 42 COG2899 COG2899, Uncharacterized protein conserved in bacteria Function unknown 85858653 Common - hypothetical cytosolic protein SYN_02900 20 COG5553 COG5553, Predicted metal-dependent enzyme of the double-stranded beta helix superfamily General function prediction only 85860400 Nonpathogen - hypothetical cytosolic protein SYN_03762 1 None None None 85859790 Common - tRNA delta(2)-isopentenylpyrophosphate transferase SYN_02888 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 85859998 Common - xanthine permease SYN_00733 99 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 85858658 Common - sporulation related protein SYN_02905 41 COG2385 SpoIID, Sporulation protein and related proteins Cell division and chromosome partitioning 85858428 Nonpathogen - hypothetical cytosolic protein SYN_02263 1 None None None 85859580 Common - ribonuclease E SYN_02196 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 85857942 Common - rhodanese-related sulfurtransferase SYN_00143 142 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 85859217 Common - DNA topoisomerase I SYN_02798 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 85857872 Nonpathogen - hypothetical cytosolic protein SYN_00006 1 None None None 85857879 Common - hypothetical cytosolic protein SYN_03262 21 COG1743 COG1743, Adenine-specific DNA methylase containing a Zn-ribbon DNA replication, recombination, and repair 85858525 Common - cell division protein SYN_01745 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 85859330 Nonpathogen - hypothetical membrane protein SYN_00053 1 None None None 85859109 Common - sec-independent protein translocase protein SYN_03204 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 85859071 Common - coA pyrophosphatase SYN_00932 7 None None None 85860771 Nonpathogen - hypothetical cytosolic protein SYN_00350 1 None None None 85859450 Common - ribonuclease PH SYN_00902 179 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 85858958 Common - 2-amino-3-ketobutyrate coenzyme A ligase SYN_00565 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 85859648 Nonpathogen - hypothetical membrane protein SYN_01925 1 None None None 85859999 Common - uncharacterized protein involved in formate dehydrogenase formation SYN_00734 43 COG3058 FdhE, Uncharacterized protein involved in formate dehydrogenase formation Posttranslational modification, protein turnover, chaperones 85859086 Common - permease SYN_00414 153 COG0795 COG0795, Predicted permeases General function prediction only 85860925 Common - peptidoglycan binding protein SYN_00224 74 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 85858968 Common - SAM-dependent methyltransferase SYN_01029 135 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 85860593 Nonpathogen - zinc metalloprotease SYN_01286 30 COG1913 COG1913, Predicted Zn-dependent proteases General function prediction only 85859081 Common - aspartate 1-decarboxylase SYN_00419 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 85859208 Nonpathogen - hypothetical cytosolic protein SYN_02807 1 None None None 85860828 Common - malonyl-CoA-[acyl-carrier-protein] transacylase SYN_01700 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 85858125 Common - general secretion pathway protein F SYN_01284 148 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 85859973 Common - dim6/ntab flavoprotein family SYN_00710 49 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 85859609 Common - formate--tetrahydrofolate ligase SYN_02008 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 85860265 Common - hypothetical membrane protein SYN_02506 16 COG5608 COG5608, Conserved secreted protein Function unknown 85858135 Common - LSU ribosomal protein L1P SYN_00068 245 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 85858413 Common - hypothetical cytosolic protein SYN_02278 203 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 85859324 Common - two-component response regulator SYN_02530 226 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 85859911 Nonpathogen - coA transferase SYN_00658 2 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 85860280 Common - CoA binding protein SYN_02520 147 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 85858802 Common - hypothetical membrane protein SYN_03169 42 COG3786 COG3786, Uncharacterized protein conserved in bacteria Function unknown 85860251 Common - Haloacid dehalogenase-like hydrolase SYN_02491 63 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 85859714 Nonpathogen - hypothetical cytosolic protein SYN_01972 3 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 85859897 Common - site-specific recombinase SYN_00509 92 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 85860884 Common - 4Fe-4S protein SYN_01642 16 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 85859514 Nonpathogen - hypothetical cytosolic protein SYN_01856 1 None None None 85858139 Common - DNA-directed RNA polymerase beta' chain SYN_00063 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 85859078 Common - hypothetical membrane protein SYN_00422 23 COG3216 COG3216, Uncharacterized protein conserved in bacteria Function unknown 85857886 Common - cold shock DNA-binding domain SYN_00019 44 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 85858857 Nonpathogen - hypothetical cytosolic protein SYN_01334 1 None None None 85860004 Common - cell division inhibitor SYN_00738 24 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 85860964 Common - F0F1 ATP synthase subunit A SYN_02101 204 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 85859050 Common - transcriptional regulator, Fur family SYN_00953 74 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 85859652 Common - ATP-dependent RNA helicase SYN_01929 239 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 85860850 Common - acetyltransferase (GNAT) family protein SYN_01678 9 COG0456 RimI, Acetyltransferases General function prediction only 85857898 Common - molecular chaperone SYN_00031 154 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 85858612 Common - transposase SYN_02945 64 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 85858941 Common - NADH-quinone oxidoreductase chain F SYN_01369 170 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 85860977 Common - a/g-specific DNA glycosylase SYN_02088 239 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 85859391 Common - predicted Zn-dependent peptidase SYN_02796 176 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 85860443 Common - Oxidoreductase SYN_02682 213 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 85859282 Common - putative translaldolase SYN_02165 164 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 85860457 Common - UDP-glucose 4-epimerase SYN_02668 223 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 85857962 Common - signal transduction histidine kinase SYN_02213 224 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 85858096 Nonpathogen - hypothetical cytosolic protein SYN_03300 1 None None None 85860956 Common - fog:tpr repeat protein SYN_01301 25 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 85858375 Nonpathogen - hypothetical cytosolic protein SYN_03374 1 None None None 85860540 Common - sigma-54-dependent transcriptional regulator SYN_01809 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 85859097 Common - DNA repair protein SYN_03201 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 85859152 Common - ATP-NAD kinase SYN_02863 239 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 85857848 Common - DNA gyrase subunit B SYN_02049 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 85859148 Common - dTDP-glucose 4,6-dehydratase SYN_02866 233 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 85860086 Common - queuosine biosynthesis protein SYN_01561 177 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 85858348 Nonpathogen - hypothetical cytosolic protein SYN_02344 1 None None None 85860288 Common - phosphate butyryltransferase SYN_01211 67 COG0280 Pta, Phosphotransacetylase Energy production and conversion 85858297 Nonpathogen - hypothetical cytosolic protein SYN_02606 1 None None None 85858034 Common - acyl carrier protein SYN_02364 20 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 85858390 Common - mu-like prophage Flumu F protein SYN_02302 27 COG2369 COG2369, Uncharacterized protein, homolog of phage Mu protein gp30 Function unknown 85858271 Nonpathogen - hypothetical membrane protein SYN_01102 1 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 85859014 Nonpathogen - hypothetical cytosolic protein SYN_00120 1 None None None 85859042 Common - putative inhibitor of MCP methylation SYN_00961 30 COG1406 COG1406, Predicted inhibitor of MCP methylation, homolog of CheC Cell motility and secretion 85859386 Common - membrane-bound lytic murein transglycosylase D precursor SYN_02791 134 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 85859471 Nonpathogen - hypothetical cytosolic protein SYN_00763 1 None None None 85859124 Common - ATPase SYN_01507 48 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 85859735 Common hppA membrane-bound proton-translocating pyrophosphatase SYN_02772 98 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 85859553 Common - hypothetical cytosolic protein SYN_01895 11 None None None 85859626 Nonpathogen - hypothetical cytosolic protein SYN_02460 1 None None None 85858951 Common - mannose-6-phosphate isomerase SYN_01359 125 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 85860064 Nonpathogen - hypothetical membrane protein SYN_01540 1 None None None 85857853 Nonpathogen - hypothetical membrane protein SYN_02044 1 None None None 85858835 Nonpathogen - hypothetical cytosolic protein SYN_00408 1 None None None 85858169 Common - bacterial protein translation Initiation Factor 1 (IF-1) SYN_01597 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 85860623 Nonpathogen - hypothetical cytosolic protein SYN_01063 1 None None None 85858737 Common - peptidyl-prolyl cis-trans isomerase SYN_02487 165 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 85858974 Common - mating response propein to a peptide sex pheromone SYN_01025 38 COG1916 COG1916, Uncharacterized homolog of PrgY (pheromone shutdown protein) Function unknown 85859699 Common - tryptophan synthase subunit beta SYN_01988 224 COG1350 COG1350, Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB) General function prediction only 85859587 Nonpathogen - hypothetical cytosolic protein SYN_03055 1 None None None 85860154 Common - small heat shock protein SYN_00784 110 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 85859341 Common ileS isoleucyl-tRNA synthetase SYN_01454 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 85860521 Common infB translation initiation factor IF-2 SYN_01787 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 85858073 Common - outer membrane B12 receptor SYN_01425 128 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 85858308 Common - cyclic nucleotide-binding domain protein SYN_00248 179 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 85858230 Common - glycosyltransferase SYN_01142 191 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 85859960 Nonpathogen - hypothetical cytosolic protein SYN_00699 1 None None None 85858947 Common - adenylate and guanylate cyclase catalytic domain protein SYN_01363 224 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 85858218 Nonpathogen - hypothetical cytosolic protein SYN_01155 1 None None None 85859255 Common - ABC-type molybdate transport system, periplasmic component SYN_00269 160 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 85860507 Common - hypothetical protein SYN_01773 7 COG3168 PilP, Tfp pilus assembly protein PilP Cell motility and secretion / Intracellular trafficking and secretion 85858086 Common - cold shock protein SYN_01437 184 COG1278 CspC, Cold shock proteins Transcription 85858997 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase SYN_00107 146 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 85859405 Common - GTP-binding protein LepA SYN_02187 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 85859420 Nonpathogen - hypothetical cytosolic protein SYN_01039 3 None None None 85860800 Nonpathogen - predicted DNA-binding protein with PD1-like DNA-binding motif SYN_00317 13 COG1661 COG1661, Predicted DNA-binding protein with PD1-like DNA-binding motif General function prediction only 85859474 Common - hypothetical membrane protein SYN_00612 10 None None None 85860807 Common - methylthioribose salvage protein SYN_00310 131 COG0182 COG0182, Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 85859259 Common - NAD-dependent aldehyde dehydrogenase SYN_00265 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 85858814 Common - flagellar basal-body rod protein SYN_01467 83 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 85859743 Common - DNA mismatch repair protein SYN_01405 199 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 85860809 Common - aspartyl/glutamyl-tRNA(asn/gln) amidotransferase subunit A SYN_00308 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 85858369 Nonpathogen - hypothetical cytosolic protein SYN_02322 2 None None None 85860704 Common - lactoylglutathione related lyase SYN_02418 56 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 85858971 Nonpathogen - hypothetical protein SYN_01027 1 None None None 85858278 Common - TPR repeat-containing protein SYN_01095 145 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 85857867 Nonpathogen - hypothetical cytosolic protein SYN_00002 1 None None None 85859252 Common - molybdopterin biosynthesis MoeA protein SYN_00272 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 85859755 Nonpathogen - lysM domain protein SYN_01418 2 COG3170 FimV, Tfp pilus assembly protein FimV Cell motility and secretion / Intracellular trafficking and secretion 85860613 Common - tolR protein SYN_01052 9 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 85858426 Common - transcriptional regulator AsnC family SYN_02265 58 COG1522 Lrp, Transcriptional regulators Transcription 85858063 Common - MFS superfamily transporter SYN_02583 70 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 85859359 Nonpathogen - hypothetical cytosolic protein SYN_01963 2 None None None 85860002 Common - outer membrane protein slp precursor SYN_00737 22 COG3065 Slp, Starvation-inducible outer membrane lipoprotein Cell envelope biogenesis, outer membrane 85858805 Common - export ABC transporter permease protein SYN_01457 108 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 85859409 Common - acylphosphatase SYN_02936 126 COG1254 AcyP, Acylphosphatases Energy production and conversion 85860599 Common - response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain SYN_01292 220 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 85859370 Common - predicted phosphatase SYN_02775 170 COG0546 Gph, Predicted phosphatases General function prediction only 85858315 Nonpathogen - hypothetical cytosolic protein SYN_03346 1 None None None 85860445 Nonpathogen - hypothetical membrane protein SYN_02680 1 None None None 85858579 Nonpathogen - hypothetical cytosolic protein SYN_03416 1 None None None 85859505 Common - ATPase of AAA+ superfamily SYN_01847 35 COG1483 COG1483, Predicted ATPase (AAA+ superfamily) General function prediction only 85859322 Common - metallo-beta-lactamase superfamily SYN_02533 194 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 85860947 Nonpathogen - hypothetical membrane protein SYN_03079 1 None None None 85859839 Nonpathogen - hypothetical membrane protein SYN_00455 1 None None None 85858832 Common - ABC-type transport system involved in resistance to organic solvents, permease component SYN_00411 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 85859163 Common - zn-dependent hydrolase including glyoxylases SYN_02851 135 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 85858347 Nonpathogen - hypothetical membrane protein SYN_02345 2 None None None 85860018 Nonpathogen - hypothetical cytosolic protein SYN_00751 1 None None None 85860895 Common - glutamate synthase (NADPH) SYN_01629 222 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 85859384 Common lnt apolipoprotein N-acyltransferase SYN_02789 167 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 85860889 Common - signal transduction histidine kinase SYN_01636 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 85858546 Nonpathogen - hypothetical cytosolic protein SYN_03412 1 None None None 85859664 Common - tryptophan synthase alpha chain SYN_01941 218 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 85860486 Common - long-chain fatty acid transport protein SYN_02639 67 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 85860419 Common - hypothetical cytosolic protein SYN_00095 4 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 85858361 Nonpathogen - hypothetical membrane protein SYN_03038 1 None None None 85858245 Common - RTX family of calcium-binding proteins SYN_01127 143 None None None 85860661 Common - mechanosensitive ion channel SYN_02629 219 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 85858570 Nonpathogen - hypothetical membrane protein SYN_02438 1 None None None 85858482 Common - phosphohydrolase SYN_00539 153 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 85859830 Common - cysteine synthase SYN_00446 220 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 85858515 Common - 4-amino-4-deoxychorismate lyase SYN_01735 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 85859136 Common - hypothetical protein SYN_01495 9 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 85860882 Nonpathogen - heterodisulfide reductase, subunit A SYN_01644 30 COG1148 HdrA, Heterodisulfide reductase, subunit A and related polyferredoxins Energy production and conversion 85858143 Common - 30S ribosomal protein S7 SYN_03255 249 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 85859716 Nonpathogen - hypothetical membrane protein SYN_03002 3 None None None 85858678 Common - molybdenum cofactor biosynthesis protein C SYN_02926 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 85858627 Nonpathogen - hypothetical cytosolic protein SYN_03437 1 None None None 85859704 Common - chaperone protein SYN_01983 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 85858000 Common - hypothetical protein SYN_00845 13 None None None 85859722 Common - hypothetical membrane protein SYN_00642 20 COG4241 COG4241, Predicted membrane protein Function unknown 85858281 Common - tyrosine-protein kinase SYN_03031 137 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 85860571 Common - protein translocase subunit SYN_03791 77 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 85859729 Common - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase SYN_03046 193 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 85859931 Nonpathogen - hypothetical cytosolic protein SYN_00676 1 None None None 85860668 Common - 1,4-dihydroxy-2-naphthoate polyprenyltransferase SYN_02622 117 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 85859337 Common - phosphate transport system protein SYN_00060 197 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 85859394 Common - Fe-S oxidoreductase SYN_02176 100 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 85860048 Common - protein translocase subunit SYN_01523 163 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 85858432 Common - cheY-like receiver domain protein SYN_02258 221 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 85858431 Nonpathogen - hypothetical membrane protein SYN_02259 1 None None None 85860558 Common - ubiquinone/menaquinone biosynthesis methyltransferase SYN_00297 212 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 85859414 Nonpathogen - hypothetical membrane protein SYN_02932 1 COG5416 COG5416, Uncharacterized integral membrane protein Function unknown 85860877 Common - NADH:ubiquinone oxidoreductase, NADH-binding subunit SYN_01648 186 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 85858257 Nonpathogen - hypothetical cytosolic protein SYN_01116 1 None None None 85857967 Nonpathogen - hypothetical cytosolic protein SYN_03238 1 None None None 85859957 Nonpathogen - hypothetical cytosolic protein SYN_00696 1 None None None 85860410 Common - hypothetical cytosolic protein SYN_03122 10 None None None 85858854 Common - transposase SYN_03172 91 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 85860432 Common - acetyltransferase SYN_02693 50 COG0456 RimI, Acetyltransferases General function prediction only 85857881 Common - protein translocase subunit SYN_00014 65 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 85859354 Common - hypothetical protein SYN_00385 29 COG4313 COG4313, Protein involved in meta-pathway of phenol degradation Energy production and conversion 85858264 Common - oligosaccharide translocase (flippase) SYN_01109 106 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 85859860 Common - GMP synthase (glutamine-hydrolyzing) SYN_00475 65 COG1606 COG1606, ATP-utilizing enzymes of the PP-loop superfamily General function prediction only 85858885 Common - transposase IS116/IS110/IS902 family protein SYN_00390 101 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 85860241 Common - arsenical pump membrane protein SYN_01580 154 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 85860959 Nonpathogen - hypothetical membrane protein SYN_02106 3 None None None 85860115 Common - glycosyltransferase involved in cell wall biogenesis SYN_00822 170 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 85860950 Common - cold shock protein SYN_01297 181 COG1278 CspC, Cold shock proteins Transcription 85860600 Common - oxygen-insensitive NAD(P)H nitroreductase / dihydropteridine reductase SYN_01293 42 COG0778 NfnB, Nitroreductase Energy production and conversion 85860863 Common - sodium-translocating NADH-quinone reductase subunit B SYN_01663 76 COG4658 RnfD, Predicted NADH:ubiquinone oxidoreductase, subunit RnfD Energy production and conversion 85859319 Common - isopropylmalate/homocitrate/citramalate synthases SYN_02536 190 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 85859052 Common - tetratricopeptide repeat family protein SYN_00951 143 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 85858199 Nonpathogen - hypothetical membrane protein SYN_00516 1 COG1043 LpxA, Acyl- acyl carrier protein 85858411 Common - polysaccharide acetyltransferase SYN_02281 52 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 85858326 Nonpathogen - hypothetical cytosolic protein SYN_03354 1 None None None 85860091 Common - NAD-dependent oxidoreductase SYN_01566 178 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 85858933 Common - transposase and inactivated derivatives SYN_03180 26 None None None 85858603 Common - fructose-bisphosphate aldolase SYN_02954 117 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 85859431 Common - translation elongation factor Ts SYN_03145 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 85858760 Nonpathogen - hypothetical cytosolic protein SYN_02740 1 None None None 85860650 Common - glycerate dehydrogenase / hydroxypyruvate reductase SYN_00869 86 COG2379 GckA, Putative glycerate kinase Carbohydrate transport and metabolism 85858476 Common - ATP synthase gamma chain SYN_00545 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 85859028 Common - chemotaxis protein SYN_00975 133 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 85860394 Common - (s)-2-hydroxy-acid oxidase chain D SYN_01167 181 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 85860053 Common - nramp family metal ion transport protein SYN_01528 105 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 85860212 Common - formate dehydrogenase iron-sulfur subunit SYN_00604 164 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 85859615 Nonpathogen - hypothetical cytosolic protein SYN_02001 1 None None None 85860810 Common - aspartyl/glutamyl-tRNA(asn/gln) amidotransferase subunit C SYN_00307 148 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 85860309 Common - cytidylate kinase SYN_01231 15 COG1102 Cmk, Cytidylate kinase Nucleotide transport and metabolism 85859273 Common - ornithine carbamoyltransferase SYN_02156 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 85858704 Common - lipid A biosynthesis lauroyl acyltransferase SYN_00133 132 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 85858977 Common - seceted metal-dependent hydrolase of the beta-lactamase superfamily III SYN_01022 127 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 85859906 Common - transcriptional regulator, MarR family SYN_00652 149 COG1846 MarR, Transcriptional regulators Transcription 85859293 Common - cold shock protein SYN_02175 182 COG1278 CspC, Cold shock proteins Transcription 85858460 Common - capsule biosynthesis protein SYN_02231 50 COG2843 PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) Cell envelope biogenesis, outer membrane 85858589 Common - transposase SYN_03135 34 None None None 85859277 Common - diaminopimelate decarboxylase SYN_02160 218 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 85859874 Nonpathogen - hypothetical cytosolic protein SYN_00488 1 None None None 85857989 Common - formate dehydrogenase, cytochrome b subunit SYN_00632 68 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 85857982 Common - iron-sulfur protein associated with hydrogenases SYN_00625 92 COG1908 FrhD, Coenzyme F420-reducing hydrogenase, delta subunit Energy production and conversion 85860481 Nonpathogen - hypothetical membrane protein SYN_02645 5 None None None 85860257 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit alpha SYN_02498 139 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 85858925 Common - NADH-quinone oxidoreductase chain F SYN_02139 166 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 85859280 Common - 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) SYN_02163 202 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 85858226 Common - acyl-CoA dehydrogenase SYN_01146 163 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 85858952 Common - hypothetical membrane protein SYN_01358 7 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 85859383 Common - oxygen-independent coproporphyrinogen III oxidase, Fe-S oxidoreductase SYN_02788 87 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 85859627 Common - deoxyhypusine synthase-like protein SYN_02461 63 COG1899 DYS1, Deoxyhypusine synthase Posttranslational modification, protein turnover, chaperones 85860625 Common - outer membrane protein SYN_01064 134 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 85858106 Common - toluene tolerance protein SYN_01265 56 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 85859765 Common - hypothetical cytosolic protein SYN_01305 27 None None None 85858655 Common - predicted phosphotransferase related to Ser/Thr protein kinases SYN_02902 61 COG3178 COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases General function prediction only 85860746 Common - rhodanese domain protein SYN_03818 20 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 85859969 Common - hypothetical protein SYN_00707 13 None None None 85860039 Nonpathogen - hypothetical cytosolic protein SYN_03699 1 None None None 85859894 Nonpathogen - hypothetical cytosolic protein SYN_00507 3 None None None 85859930 Nonpathogen - hypothetical cytosolic protein SYN_00675 9 None None None 85858698 Nonpathogen - response regulator receiver domain SYN_00127 4 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 85859114 Common - histidinol-phosphate aminotransferase SYN_01517 228 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 85860681 Common - periplasmic component of efflux system SYN_00240 163 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 85860555 Common - hypothetical cytosolic protein SYN_00300 2 None None None 85859701 Nonpathogen - hypothetical cytosolic protein SYN_01986 1 None None None 85860657 Common - beta-lysine acetyltransferase SYN_02633 20 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 85858059 Common - dihydropteroate synthase related enzyme SYN_02578 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 85859597 Common - DNA-binding protein HU SYN_02019 194 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 85860644 Common - potassium/proton antiporter SYN_00864 207 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 85857861 Common - sigma factor SYN_02037 156 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 85860215 Common - ferredoxin--NADP(+) reductase subunit alpha SYN_00607 92 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 85858777 Common - adenine deaminase SYN_02726 75 COG1001 AdeC, Adenine deaminase Nucleotide transport and metabolism 85859886 Nonpathogen - hypothetical cytosolic protein SYN_00499 1 None None None 85859495 Common - mreB-like ATPase involved in cell division SYN_01836 24 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 85859499 Nonpathogen - hypothetical cytosolic protein SYN_01841 1 None None None 85858204 Common - phosphoribosylformylglycinamidine synthase SYN_00521 233 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 85860708 Nonpathogen - Kunitz/bovine pancreatic trypsin inhibitor domain protein SYN_02414 4 COG4402 COG4402, Uncharacterized protein conserved in bacteria Function unknown 85857994 Common - tungsten formylmethanofuran dehydrogenase subunit E SYN_00638 27 COG2191 COG2191, Formylmethanofuran dehydrogenase subunit E Energy production and conversion 85860170 Common - hypothetical cytosolic protein SYN_00769 20 COG4752 COG4752, Uncharacterized protein conserved in bacteria Function unknown 85860119 Common - lipopolysaccharide 1,2-N-acetylglucosaminetransferase SYN_00818 220 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 85860581 Nonpathogen - hypothetical cytosolic protein SYN_03796 7 None None None 85860836 Common - acyltransferase SYN_01692 6 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 85859524 Nonpathogen - hypothetical protein SYN_01866 2 None None None 85859006 Common - Na+-transporting decarboxylase, beta subunit SYN_00115 56 COG1883 OadB, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit Energy production and conversion 85859684 Common - spore maturation protein A SYN_01085 39 COG2715 SpmA, Uncharacterized membrane protein, required for spore maturation in B.subtilis. General function prediction only 85857936 Common - heme export protein SYN_00149 53 COG1333 ResB, ResB protein required for cytochrome c biosynthesis Posttranslational modification, protein turnover, chaperones 85860537 Nonpathogen - hypothetical cytosolic protein SYN_01805 1 None None None 85857954 Nonpathogen - hypothetical cytosolic protein SYN_03237 1 None None None 85858795 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase SYN_02710 188 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 85858049 Common - 8-amino-7-oxononanoate synthase SYN_02568 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 85858810 Common - periplasmic component of efflux system SYN_01461 165 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 85858873 Common - transposase and inactivated derivatives SYN_01317 26 None None None 85860609 Common - iron(III) dicitrate-binding protein SYN_03802 24 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 85859376 Common - aspartokinase SYN_02781 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 85857909 Nonpathogen - hypothetical cytosolic protein SYN_00177 1 None None None 85858903 Common - glutaminyl-tRNA synthetase SYN_02116 246 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 85858418 Common - porphobilinogen deaminase SYN_02273 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 85860996 Common - ABC-type transport system involved in resistance to organic solvents, ATPase component SYN_02069 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 85859945 Nonpathogen - hypothetical membrane protein SYN_03099 1 None None None 85860531 Common - ribosomal large subunit pseudouridine synthase D SYN_01800 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 85858069 Common carB carbamoyl phosphate synthase large subunit SYN_02589 238 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 85860711 Nonpathogen - hypothetical cytosolic protein SYN_02412 1 None None None 85860787 Common - hypothetical protein SYN_00333 4 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 85858700 Common - nucleoside-diphosphate-sugar epimerase SYN_00129 12 COG3660 COG3660, Predicted nucleoside-diphosphate-sugar epimerase Cell envelope biogenesis, outer membrane 85859176 Common - flagellar basal body-associated protein SYN_02838 47 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 85858798 Common - methionyl-tRNA formyltransferase SYN_02707 226 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 85860928 Common - predicted N6-adenine-specific DNA methylase SYN_00221 128 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 85859787 Common - nicotinate-nucleotide pyrophosphorylase (carboxylating) SYN_02885 204 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 85858405 Common - mu-like prophage Flumu protein gp45 SYN_02287 17 COG4384 COG4384, Mu-like prophage protein gp45 Function unknown 85860420 Nonpathogen - hypothetical cytosolic protein SYN_00096 15 COG1633 COG1633, Uncharacterized conserved protein Function unknown 85859222 Common - transposase and inactivated derivatives SYN_03211 26 None None None 85858906 Nonpathogen - hypothetical cytosolic protein SYN_02119 1 None None None 85858333 Common - serine phosphatase RsbU, regulator of sigma subunit SYN_02359 143 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 85858180 Common rplM 50S ribosomal protein L13 SYN_00232 242 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 85860674 Common - cytochrome c552 SYN_02616 40 COG3303 NrfA, Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit Inorganic ion transport and metabolism 85857924 Common - hypothetical protein SYN_00162 189 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 85859692 Common - potassium uptake protein SYN_01092 140 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 85860450 Common - UDP-glucose 6-dehydrogenase SYN_02675 203 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 85859193 Nonpathogen - hypothetical cytosolic protein SYN_02822 1 None None None 85860722 Common - naphthoate synthase SYN_02400 170 COG0447 MenB, Dihydroxynaphthoic acid synthase Coenzyme metabolism 85860729 Common - peptidylarginine deiminase related enzyme SYN_02393 88 COG2957 COG2957, Peptidylarginine deiminase and related enzymes Amino acid transport and metabolism 85858510 Nonpathogen - hypothetical cytosolic protein SYN_01730 2 None None None 85860247 Common - cold shock protein SYN_02488 181 COG1278 CspC, Cold shock proteins Transcription 85860345 Common - polysaccharide deacetylase SYN_00858 94 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 85860699 Common - heterodisulfide reductase, subunit A SYN_02423 44 COG1148 HdrA, Heterodisulfide reductase, subunit A and related polyferredoxins Energy production and conversion 85857929 Common - pyruvate:ferredoxin oxidoreductase delta subunit SYN_00156 54 COG1144 COG1144, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit Energy production and conversion 85860390 Nonpathogen - hypothetical cytosolic protein SYN_01171 6 None None None 85860773 Common - pyridoxal phosphate biosynthetic protein SYN_00348 105 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 85857940 Common - rhodanese-like domain protein SYN_00145 62 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 85860402 Common - ATPases involved in chromosome partitioning SYN_03123 228 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 85858827 Common - alanine racemase SYN_01482 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 85859850 Common - cell division protein ftsY SYN_00465 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 85857947 Nonpathogen - hypothetical cytosolic protein SYN_00139 1 None None None 85858545 Nonpathogen - hypothetical cytosolic protein SYN_03413 1 None None None 85860474 Common - methyltransferase SYN_02651 44 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 85860237 Nonpathogen - hypothetical cytosolic protein SYN_01584 1 None None None 85860274 Common - hypothetical transporter protein SYN_02514 8 None None None 85859064 Common - GTP-binding protein TypA/BipA SYN_00939 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 85857914 Nonpathogen - hypothetical cytosolic protein SYN_03267 1 None None None 85858001 Common - molybdate-binding protein domain SYN_00844 72 COG1910 COG1910, Periplasmic molybdate-binding protein/domain Inorganic ion transport and metabolism 85859859 Common - phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit SYN_00474 64 COG1691 COG1691, NCAIR mutase (PurE)-related proteins General function prediction only 85860333 Common - serine acetyltransferase SYN_01257 191 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 85858449 Nonpathogen - hypothetical cytosolic protein SYN_03393 1 None None None 85859485 Common - type III restriction-modification system methylation subunit SYN_01825 93 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 85859526 Common - hypothetical cytosolic protein SYN_01868 26 None None None 85857870 Common - hypothetical cytosolic protein SYN_00004 39 COG2979 COG2979, Uncharacterized protein conserved in bacteria Function unknown 85859185 Common - flagellar biosynthesis protein SYN_02829 247 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 85858965 Common - putative inhibitor of septum formation protein SYN_00572 198 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 85858174 Common - LSU ribosomal protein L17P SYN_01603 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 85858845 Nonpathogen - hypothetical protein SYN_03064 1 None None None 85858316 Nonpathogen - hypothetical cytosolic protein SYN_00255 1 None None None 85859661 Common - 3-dehydroquinate dehydratase SYN_01938 83 COG0710 AroD, 3-dehydroquinate dehydratase Amino acid transport and metabolism 85860999 Common - hlyD family secretion protein SYN_02066 132 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 85859994 Common - ribosomal large subunit pseudouridine synthase D SYN_00730 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 85859753 Nonpathogen - hypothetical cytosolic protein SYN_01416 1 None None None 85860793 Common - acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases SYN_00326 192 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 85860368 Nonpathogen - hypothetical cytosolic protein SYN_01193 7 None None None 85859134 Common - flp pilus assembly protein, ATPase SYN_01497 225 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 85859506 Common - adenine-specific DNA methylase containing a zn-ribbon SYN_01848 46 COG1743 COG1743, Adenine-specific DNA methylase containing a Zn-ribbon DNA replication, recombination, and repair 85860611 Common - methyltransferase SYN_01050 36 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 85858895 Common - transposase SYN_00398 84 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 85858815 Common - flagellar basal-body rod protein SYN_01468 124 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 85860763 Nonpathogen - hypothetical cytosolic protein SYN_00358 1 None None None 85859473 Common - hypothetical membrane protein SYN_00613 11 COG3784 COG3784, Uncharacterized protein conserved in bacteria Function unknown 85859244 Common - radical SAM superfamily protein SYN_00279 67 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 85859018 Common - D-3-phosphoglycerate dehydrogenase SYN_00123 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 85861004 Nonpathogen - hypothetical cytosolic protein SYN_03857 2 None None None 85858751 Common - hypothetical cytosolic protein SYN_02748 23 None None None 85860232 Nonpathogen - hypothetical cytosolic protein SYN_01587 1 None None None 85860910 Common - glutamine synthetase SYN_01613 94 COG3968 COG3968, Uncharacterized protein related to glutamine synthetase General function prediction only 85859806 Common - glutamyl-tRNA synthetase SYN_01399 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 85859215 Common - lytic transglycosylase SYN_02800 176 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 85858647 Nonpathogen - phosphohydrolase SYN_03150 3 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 85859971 Common - transposase SYN_03102 84 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 85858580 Nonpathogen - hypothetical cytosolic protein SYN_03417 1 None None None 85860082 Common - general secretion pathway protein C SYN_01558 10 COG3031 PulC, Type II secretory pathway, component PulC Intracellular trafficking and secretion 85858769 Common - protein HipA SYN_02732 71 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 85858202 Nonpathogen - hypothetical membrane protein SYN_00519 2 None None None 85860084 Common - queuosine biosynthesis protein SYN_01559 127 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 85860296 Common - hypothetical membrane protein SYN_03745 35 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 85860962 Common - F0F1-type ATP synthase, subunit b SYN_02103 41 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 85860500 Common - lysine decarboxylase family SYN_01766 108 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 85858454 Common - hypothetical cytosolic protein SYN_02239 25 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 85858928 Nonpathogen - hypothetical cytosolic protein SYN_02142 2 None None None 85860637 Nonpathogen - hypothetical membrane protein SYN_02990 1 None None None 85859908 Common - phosphate butyryltransferase SYN_00654 65 COG0280 Pta, Phosphotransacetylase Energy production and conversion 85860640 Common - response regulator receiver domain SYN_01078 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 85859030 Common - sigma-54 dependent transcriptional regulator SYN_00973 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 85859565 Common - co-chaperonin SYN_01908 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 85857976 Common - ABC-type phosphate transport system, periplasmic component SYN_02226 113 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 85859469 Common rpmB 50S ribosomal protein L28 SYN_00885 150 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 85861009 Common - 3-deoxy-manno-octulosonate cytidylyltransferase SYN_02057 143 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 85860428 Nonpathogen - hypothetical cytosolic protein SYN_02697 1 None None None 85858778 Nonpathogen - hypothetical cytosolic protein SYN_02725 1 None None None 85859846 Common - glutamate formiminotransferase SYN_00461 22 COG3643 COG3643, Glutamate formiminotransferase Amino acid transport and metabolism 85858834 Common - ABC-type transport system involved in resistance to organic solvents, periplasmic component SYN_00409 107 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 85859731 Common - LSU ribosomal protein L25P SYN_02768 173 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 85860523 Common - hypothetical protein SYN_01790 171 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 85859090 Common - HD-GYP domain protein SYN_02361 117 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 85860128 Nonpathogen - hypothetical cytosolic protein SYN_00809 1 None None None 85860483 Common - acetyl-CoA acetyltransferase SYN_02642 186 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 85858098 Nonpathogen - hypothetical membrane protein SYN_01449 1 None None None 85860542 Common - nitrobenzoate nitroreductase SYN_01811 125 COG0778 NfnB, Nitroreductase Energy production and conversion 85859964 Nonpathogen - hypothetical cytosolic protein SYN_03101 7 COG1432 COG1432, Uncharacterized conserved protein Function unknown 85859650 Common - hypothetical membrane protein SYN_01927 4 None None None 85859928 Nonpathogen - hypothetical cytosolic protein SYN_03674 1 None None None 85860129 Common - hypothetical cytosolic protein SYN_03717 11 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 85858236 Common - acetyltransferase SYN_01136 187 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 85859816 Common - phosphoglycerate mutase SYN_01002 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 85859102 Common - amidophosphoribosyltransferase family protein SYN_01338 178 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 85859568 Common - uvrD/rep helicase SYN_01911 210 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 85858771 Nonpathogen - hypothetical cytosolic protein SYN_03166 1 None None None 85859446 Common - 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase SYN_00906 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 85859343 Common - hypothetical cytosolic protein SYN_01452 26 COG3809 COG3809, Uncharacterized protein conserved in bacteria Function unknown 85858075 Common - ABC-type Fe3+-siderophore transport system, permease component SYN_01427 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 85859533 Common - DNA transfer and F pilus assembly protein SYN_01875 9 None None None 85858948 Nonpathogen - hypothetical cytosolic protein SYN_01362 1 None None None 85858225 Common - arginase SYN_01147 139 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 85857987 Common - formate dehydrogenase, iron-sulfur subunit SYN_00630 210 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 85860859 Common - iron-sulfur cluster assembly/repair protein SYN_01668 135 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 85860208 Common - hydrogenase maturation protein SYN_00600 113 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 85860312 Common - methyl-accepting chemotaxis protein SYN_01236 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 85860397 Nonpathogen - hypothetical cytosolic protein SYN_01165 1 None None None 85860741 Common - type II secretory pathway ExeA domain component N SYN_00379 8 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 85858159 Common rplE 50S ribosomal protein L5 SYN_03314 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 85859673 Common - NAD(P)H-flavin oxidoreductase SYN_02764 118 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 85860736 Common - hypothetical cytosolic protein SYN_02386 34 COG3809 COG3809, Uncharacterized protein conserved in bacteria Function unknown 85857855 Common - DNA modification methylase SYN_02042 119 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 85859122 Nonpathogen - hypothetical cytosolic protein SYN_03526 2 None None None 85858502 Nonpathogen - hypothetical cytosolic protein SYN_01722 1 None None None 85860546 Common - translation initiation inhibitor SYN_01814 194 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 85858467 Common - rod shape-determining protein SYN_00554 234 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 85860563 Common - ribonuclease H SYN_00291 174 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 85858876 Common - nucleotidyltransferase/DNA polymerase involved in DNA repair SYN_01314 175 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 85859154 Common - acetyltransferase SYN_02861 56 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 85859948 Common - neutral zinc metallopeptidase family SYN_00688 87 COG2321 COG2321, Predicted metalloprotease General function prediction only 85858013 Nonpathogen - glutamate synthase [NADPH] small chain SYN_02385 29 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 85858917 Common - zinc transporter ZupT SYN_02130 89 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 85859143 Nonpathogen - flp/fap pilin component SYN_01488 1 COG3847 Flp, Flp pilus assembly protein, pilin Flp Intracellular trafficking and secretion 85858488 Common - tRNA nucleotidyltransferase SYN_00533 228 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 85858606 Common - glucokinase SYN_02951 91 COG0837 Glk, Glucokinase Carbohydrate transport and metabolism 85858052 Nonpathogen - hypothetical membrane protein SYN_02571 1 None None None 85860496 Nonpathogen - hypothetical cytosolic protein SYN_03775 1 None None None 85859697 Common - recombination factor protein RarA SYN_01990 238 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 85859264 Nonpathogen - hypothetical cytosolic protein SYN_02147 1 None None None 85858837 Nonpathogen - hypothetical cytosolic protein SYN_00406 3 None None None 85859555 Nonpathogen - acetyltransferase (GNAT) family SYN_03588 1 COG0456 RimI, Acetyltransferases General function prediction only 85860621 Common - formylmethanofuran dehydrogenase subunit E SYN_01060 37 COG2191 COG2191, Formylmethanofuran dehydrogenase subunit E Energy production and conversion 85858956 Nonpathogen - hypothetical cytosolic protein SYN_00563 1 None None None 85859585 Common - seryl-tRNA synthetase SYN_00102 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 85860856 Common - molybdopterin dependent oxidoreductase SYN_01672 184 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 85858855 Common - transposase SYN_03173 38 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 85859459 Common - chaperone protein SYN_00894 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 85860300 Nonpathogen - hypothetical cytosolic protein SYN_03746 1 None None None 85858239 Common - o-antigen polymerase SYN_01133 5 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 85858187 Common - recA protein SYN_02028 241 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 85860971 Nonpathogen - hypothetical cytosolic protein SYN_02094 2 None None None 85858609 Common - acriflavin resistance periplasmic protein SYN_02948 157 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 85857877 Common - ATPase SYN_00010 58 COG4637 COG4637, Predicted ATPase General function prediction only 85859775 Common - carbonic anhydrase SYN_02875 174 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 85859203 Common - flagellar hook-associated protein 1 SYN_02812 125 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 85860897 Common - carbamoyl phosphate synthase small subunit SYN_01627 235 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 85858519 Common - division specific D,D-transpeptidase / cell division protein SYN_01739 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 85860096 Common - lipoprotein releasing system ATP-binding protein SYN_00922 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 85858523 Common - phospho-N-acetylmuramoyl-pentapeptide-transferase SYN_01743 223 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 85860751 Common - benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB SYN_00370 37 COG1775 HgdB, Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB Amino acid transport and metabolism 85858481 Nonpathogen - hypothetical cytosolic protein SYN_00540 1 None None None 85860105 Common - transglutaminase-like superfamily member SYN_00833 86 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 85859332 Nonpathogen - hypothetical cytosolic protein SYN_00055 1 None None None 85858735 Common - calcium-transporting ATPase SYN_02485 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 85859603 Nonpathogen - hypothetical cytosolic protein SYN_02014 1 None None None 85859869 Common - integrase SYN_00484 111 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 85860282 Common - ADP-ribosylglycohydrolase SYN_02522 47 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 85858140 Common - SSU ribosomal protein S12P SYN_03254 214 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 85858746 Common - ATPases involved in DNA repair SYN_02754 46 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 85857969 Common - NAD/FAD binding domain, oxidoreductase SYN_02220 139 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 85858243 Common - mannose-1-phosphate guanyltransferase SYN_01129 232 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 85859398 Common - membrane protease subunit, stomatin/prohibitin -like protein SYN_02180 205 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 85859326 Common - radical SAM superfamily SYN_02528 167 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 85859239 Nonpathogen - hypothetical protein SYN_03862 32 COG1148 HdrA, Heterodisulfide reductase, subunit A and related polyferredoxins Energy production and conversion 85858262 Common - membrane-bound O-acyltransferase SYN_01111 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 85859084 Common - S-adenosyl-L-homocysteine hydrolase SYN_00416 176 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 85858150 Common - SSU ribosomal protein S19P SYN_00989 244 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 85858783 Common - flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase SYN_02719 23 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 85860572 Nonpathogen - hypothetical cytosolic protein SYN_03792 1 None None None 85858807 Common - export ABC transporter ATP-binding protein SYN_01459 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 85859049 Common - ABC-type metal ion transport system, periplasmic component SYN_00954 181 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 85859363 Common - enzyme related to GTP cyclohydrolase I SYN_01967 112 COG0780 COG0780, Enzyme related to GTP cyclohydrolase I General function prediction only 85860201 Common - thioredoxin peroxidase SYN_00591 196 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 85858328 Nonpathogen - hypothetical cytosolic protein SYN_03356 1 None None None 85858666 Nonpathogen - hypothetical membrane protein SYN_02914 1 None None None 85859986 Nonpathogen - hypothetical cytosolic protein SYN_00722 1 None None None 85857980 Nonpathogen - nicotinamide mononucleotide adenylyltransferase SYN_00623 21 COG1056 NadR, Nicotinamide mononucleotide adenylyltransferase Coenzyme metabolism 85858305 Common - hydroxylamine reductase SYN_02614 74 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 85859077 Common - o-sialoglycoprotein endopeptidase SYN_00423 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 85859748 Common - isocitrate dehydrogenase SYN_01410 76 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 85860824 Nonpathogen - hypothetical cytosolic protein SYN_03827 1 None None None 85857884 Common - superfamily II DNA/RNA helicase, SNF2 family SYN_00017 183 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 85858620 Nonpathogen - hypothetical cytosolic protein SYN_03137 1 None None None 85860381 Common - dinitrogenase iron-molybdenum cofactor protein SYN_01180 28 COG1433 COG1433, Uncharacterized conserved protein Function unknown 85859892 Nonpathogen - hypothetical cytosolic protein SYN_00505 1 None None None 85858610 Common - acriflavin resistance plasma membrane protein SYN_02947 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 85860141 Common - ribonuclease III SYN_00796 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 85860826 Common - response regulator with sigma 54 interaction domain SYN_01702 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 85858341 Common - cation transport ATPase SYN_02351 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 85859372 Common - cell division protein SYN_02777 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 85859955 Common - pyruvate synthase delta subunit SYN_00694 64 COG1144 COG1144, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit Energy production and conversion 85860875 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA SYN_01650 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 85859967 Common - cAMP-dependent transcriptional regulator SYN_00705 159 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 85859316 Common - acetyltransferase (GNAT) family SYN_02539 37 COG0456 RimI, Acetyltransferases General function prediction only 85858137 Common - LSU ribosomal protein L7/L12 SYN_00066 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 85860404 Common - ABC-type sugar transport systems, ATPase component SYN_00079 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 85860585 Common - recB family exonuclease N SYN_02474 53 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 85858878 Common - hypothetical cytosolic protein SYN_01313 107 COG2135 COG2135, Uncharacterized conserved protein Function unknown 85858024 Common leuS leucyl-tRNA synthetase SYN_02374 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 85860941 Common - ABC-type cobalt transport system, permease component SYN_00208 89 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 85860937 Common - biotin synthase SYN_00212 179 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 85857959 Nonpathogen - hypothetical cytosolic protein SYN_02210 1 None None None 85860663 Common - trehalose 6-phosphate phosphatase SYN_02627 86 COG1877 OtsB, Trehalose-6-phosphatase Carbohydrate transport and metabolism 85858255 Nonpathogen - hypothetical cytosolic protein SYN_03331 1 None None None 85859339 Common - co-chaperonin SYN_00062 214 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 85859441 Common - aspartate-semialdehyde dehydrogenase SYN_00911 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 85860253 Common - hypothetical cytosolic protein SYN_02494 52 COG3360 COG3360, Uncharacterized conserved protein Function unknown 85860434 Common - kid repeat protein SYN_02691 3 None None None 85860498 Common - hypothetical cytosolic protein SYN_01764 30 COG3688 COG3688, Predicted RNA-binding protein containing a PIN domain General function prediction only 85859977 Nonpathogen - hypothetical cytosolic protein SYN_00714 2 None None None 85860270 Nonpathogen - hypothetical cytosolic protein SYN_03740 1 None None None 85860761 Nonpathogen - hypothetical membrane protein SYN_00360 1 None None None 85858382 Nonpathogen - hypothetical cytosolic protein SYN_03040 1 None None None 85860949 Nonpathogen - hypothetical cytosolic protein SYN_01296 5 None None None 85859727 Common - endopeptidase htpX SYN_03628 191 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 85860327 Common - cysteine desulfurase / selenocysteine lyase SYN_01251 240 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 85859365 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase SYN_01969 212 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 85858457 Common - hypothetical cytosolic protein SYN_02234 3 None None None 85858438 Nonpathogen - hypothetical cytosolic protein SYN_02252 17 COG1367 COG1367, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 85860832 Common - 3-oxoacyl- reductase SYN_01696 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 85858363 Common - hypothetical cytosolic protein SYN_02328 3 None None None 85859720 Common - SSU ribosomal protein S6P SYN_00644 204 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 85860845 Nonpathogen - hypothetical cytosolic protein SYN_03072 1 None None None 85858290 Common - glycogen phosphorylase SYN_02600 70 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 85858852 Common - transporter, drug/metabolite exporter family SYN_03170 24 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 85860880 Nonpathogen - hypothetical cytosolic protein SYN_03075 1 None None None 85859257 Common - molybdopterin biosynthesis protein SYN_00267 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 85859966 Nonpathogen - hypothetical cytosolic protein SYN_00704 4 None None None 85857858 Common - hypothetical cytosolic protein SYN_02040 10 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 85858313 Common - S-adenosylmethionine synthetase SYN_00253 43 COG1812 MetK, Archaeal S-adenosylmethionine synthetase Amino acid transport and metabolism 85859476 Common - hypothetical cytosolic protein SYN_01816 20 COG4924 COG4924, Uncharacterized protein conserved in bacteria Function unknown 85859624 Common - periplasmic component of efflux system SYN_01993 170 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 85858216 Common - ATP-dependent protease La SYN_01156 152 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 85860000 Nonpathogen - hypothetical membrane protein SYN_00735 1 None None None 85860597 Common - copper-exporting ATPase SYN_01290 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 85858868 Nonpathogen - hypothetical cytosolic protein SYN_01322 4 None None None 85859110 Common - thiamin pyrophosphokinase SYN_01522 55 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 85860805 Common - predicted inhibitor of MCP methylation, similar to CheC N SYN_00312 27 COG1406 COG1406, Predicted inhibitor of MCP methylation, homolog of CheC Cell motility and secretion 85858812 Common - signal transduction histidine kinase SYN_01465 222 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 85859799 Nonpathogen - hypothetical cytosolic protein SYN_03084 2 None None None 85860505 Nonpathogen - hypothetical protein SYN_01771 4 None None None 85859268 Common - integrase/recombinase SYN_02151 230 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 85859733 Common hppA membrane-bound proton-translocating pyrophosphatase SYN_02770 98 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 85860395 Common - Fe-S oxidoreductase SYN_01166 117 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 85859891 Common - hypothetical cytosolic protein SYN_00504 2 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 85858724 Common - tetratricopeptide repeat family protein SYN_00192 184 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 85858871 Nonpathogen - hypothetical cytosolic protein SYN_01319 1 None None None 85860706 Common - transcriptional regulator TetR family SYN_02416 110 COG1309 AcrR, Transcriptional regulator Transcription 85860714 Common - radical SAM superfamily protein SYN_02408 56 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 85858195 Nonpathogen - hypothetical membrane protein SYN_00512 1 None None None 85860134 Common - glycine reductase complex proprotein subunit of protein B SYN_00803 8 None None None 85859583 Common - hypothetical cytosolic protein SYN_00105 71 COG1872 COG1872, Uncharacterized conserved protein Function unknown 85858276 Common - hypothetical membrane protein SYN_01097 34 None None None 85860009 Common - moxR protein SYN_00743 171 COG0714 COG0714, MoxR-like ATPases General function prediction only 85860146 Common - GTP-binding protein SYN_00792 227 COG1159 Era, GTPase General function prediction only 85858421 Common - sodium-calcium exchanger SYN_02270 74 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 85858065 Common - transcrption factor sigma 54 type SYN_02585 173 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 85858990 Common - calcium-transporting ATPase SYN_01009 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 85859636 Common - ferridoxin SYN_03059 191 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 85860447 Common - asparagine synthetase (glutamine-hydrolyzing) SYN_02678 174 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 85859828 Common - 1,4-dihydroxy-2-naphthoate polyprenyltransferase SYN_00445 110 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 85859573 Common smpB SsrA-binding protein SYN_02189 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 85859489 Common - hypothetical cytosolic protein SYN_03581 4 None None None 85859119 Common - ATPase SYN_01512 37 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 85860176 Common - cell division protein SYN_00995 10 COG3147 DedD, Uncharacterized protein conserved in bacteria Function unknown 85860246 Nonpathogen - hypothetical membrane protein SYN_03012 1 None None None 85858351 Common - pentapeptide repeat protein SYN_02341 106 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 85858352 Nonpathogen - hypothetical cytosolic protein SYN_02340 1 None None None 85860193 Common - glutamate-1-semialdehyde 2,1-aminomutase SYN_00583 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 85858209 Common - calcineurin-like phosphoesterase SYN_00526 155 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 85859356 Common - dead/deah box helicase SYN_00383 221 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 85860744 Common - glycosyltransferase involved in cell wall biogenesis SYN_00376 46 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 85858101 Common - farnesyl pyrophosphate synthetase / geranyltranstransferase / farnesyltransferase / decaprenyl diphosphate synthase SYN_03252 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 85858108 Nonpathogen - hypothetical protein SYN_01267 1 None None None 85859837 Common - general secretion pathway protein K SYN_00453 15 COG3156 PulK, Type II secretory pathway, component PulK Intracellular trafficking and secretion 85858572 Common - UDP-N-acetylglucosamine pyrophosphorylase SYN_02437 227 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 85858292 Common - hypothetical cytosolic protein SYN_02601 13 COG4115 COG4115, Uncharacterized protein conserved in bacteria Function unknown 85859763 Common nadE NAD synthetase SYN_01307 179 COG0171 NadE, NAD synthase Coenzyme metabolism 85860104 Common - predicted signal transduction protein SYN_00930 57 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 85859595 Nonpathogen - hypothetical cytosolic protein SYN_02021 1 None None None 85859880 Nonpathogen - hypothetical cytosolic protein SYN_00493 1 None None None 85858044 Nonpathogen - hypothetical cytosolic protein SYN_03246 3 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 85857869 Nonpathogen - hypothetical membrane protein SYN_03228 1 None None None 85860786 Nonpathogen - hypothetical cytosolic protein SYN_00335 1 None None None 85860659 Common - hypothetical membrane protein SYN_02631 27 None None None 85859497 Nonpathogen - hypothetical cytosolic protein SYN_01839 1 None None None 85858376 Nonpathogen - hypothetical cytosolic protein SYN_02315 1 None None None 85860642 Common - potassium/proton antiporter SYN_01080 134 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 85858822 Common - hypothetical membrane protein SYN_01475 18 COG3334 COG3334, Uncharacterized conserved protein Function unknown 85859374 Common - Holo- synthase SYN_02779 165 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 85859195 Common - flagellar basal-body rod protein SYN_02820 124 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 85859288 Common - cytosol aminopeptidase SYN_02170 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 85858763 Common - hypothetical transcriptional regulatory protein SYN_02737 15 COG4190 COG4190, Predicted transcriptional regulator Transcription 85858443 Common - hypothetical cytosolic protein SYN_02247 29 COG1604 COG1604, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 85860380 Common - transcriptional regulator with sigma 54 interaction domain SYN_01181 179 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 85858797 Common - 16S rRNA m(5)C 967 methyltransferase SYN_02708 209 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 85859521 Common - pilus assembly protein SYN_01863 25 None None None 85858841 Common - deoxyribodipyrimidine photolyase SYN_00402 37 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 85859937 Common - thioredoxin peroxidase SYN_03096 193 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 85860727 Common - uncharacterized bacitracin resistance protein SYN_02394 194 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 85858994 Nonpathogen - hypothetical cytosolic protein SYN_03185 1 None None None 85860789 Common - DNA-3-methyladenine glycosylase SYN_00331 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 85857952 Nonpathogen - hypothetical cytosolic protein SYN_02203 1 None None None 85858029 Common - hypothetical protein SYN_02369 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 85859508 Nonpathogen - hypothetical cytosolic protein SYN_01850 6 None None None 85860834 Common - 3-oxoacyl-[acyl-carrier-protein] synthase SYN_01694 208 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 85858252 Nonpathogen - hypothetical protein SYN_01121 1 None None None 85859301 Nonpathogen - hypothetical cytosolic protein SYN_02554 1 None None None 85859099 Common - isoprenoid biosynthesis protein with amidotransferase-like domain SYN_01335 38 COG3155 ElbB, Uncharacterized protein involved in an early stage of isoprenoid biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 85860720 Nonpathogen - hypothetical membrane protein SYN_02402 1 None None None 85859800 Common - hypothetical membrane protein SYN_01393 4 None None None 85857978 Common - phosphoglycerate mutase SYN_00621 51 COG3635 COG3635, Predicted phosphoglycerate mutase, AP superfamily Carbohydrate transport and metabolism 85858683 Common - hypothetical cytosolic protein SYN_03449 9 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 85860652 Common - hypothetical membrane protein SYN_00871 56 COG1808 COG1808, Predicted membrane protein Function unknown 85859381 Common clpX ATP-dependent protease ATP-binding subunit SYN_02786 210 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 85858638 Common - riboflavin kinase / FMN adenylyltransferase SYN_01948 211 COG0196 RibF, FAD synthase Coenzyme metabolism 85860866 Common - sodium-translocating NADH-quinone reductase subunit E SYN_01659 76 COG4657 RnfA, Predicted NADH:ubiquinone oxidoreductase, subunit RnfA Energy production and conversion 85859275 Common - argininosuccinate lyase SYN_02158 234 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 85860696 Common - NADH:ubiquinone oxidoreductase, NADH-binding subunit SYN_02426 188 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 85860819 Common - acetolactate synthase small subunit SYN_01710 191 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 85860861 Common - ABC-type multidrug transport system, permease component SYN_01665 140 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 85860152 Common - branched-chain amino acid transport ATP-binding protein SYN_00786 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 85860869 Common - transposase SYN_03074 64 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 85858713 Nonpathogen - hypothetical cytosolic protein SYN_00181 1 None None None 85858967 Common - mannose-1-phosphate guanylyltransferase SYN_01031 161 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 85859536 Common - hypothetical cytosolic protein SYN_01879 14 COG2253 COG2253, Uncharacterized conserved protein Function unknown 85859054 Common - 3-deoxy-manno-octulosonate-8-phosphatase SYN_00949 105 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 85859809 Common - 2-c-methyl-d-erythritol 4-phosphate cytidylyltransferase SYN_01401 196 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 85858657 Common - ampG protein SYN_02904 70 None None None 85860602 Common - molybdenum transport regulatory protein, lysR family SYN_01042 46 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 85859741 Nonpathogen - spore germination protein SYN_01917 13 COG5401 COG5401, Spore germination protein General function prediction only 85858601 Common - transcriptional regulator containing sigma 54 interaction domain SYN_02956 195 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 85858706 Nonpathogen - hypothetical cytosolic protein SYN_03160 1 None None None 85859271 Common - acetylglutamate kinase SYN_02154 218 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 85859503 Common - hypothetical cytosolic protein SYN_01845 6 None None None 85860460 Common - glycosyltransferase SYN_02665 189 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 85858145 Common - SSU ribosomal protein S10P SYN_00984 246 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 85860356 Common - thioesterase superfamily protein SYN_00847 24 COG0824 FcbC, Predicted thioesterase General function prediction only 85859112 Common - thiamine biosynthesis protein ThiC SYN_01520 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 85858478 Common - ATP synthase epsilon chain SYN_00543 83 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 85860077 Nonpathogen - hypothetical membrane protein SYN_03707 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 85858594 Common - aminopeptidase SYN_02963 57 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 85857992 Common - formate dehydrogenase major subunit SYN_00635 156 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 85859814 Common - protein-L-isoaspartate o-methyltransferase SYN_01000 157 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 85858982 Nonpathogen - hypothetical cytosolic protein SYN_03510 1 None None None 85859672 Common - magnesium and cobalt transport protein corA SYN_02763 184 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 85858003 Nonpathogen - uridylate kinase SYN_00842 29 COG1608 COG1608, Predicted archaeal kinase General function prediction only 85858587 Common ruvB Holliday junction DNA helicase B SYN_02971 223 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 85859429 Nonpathogen - hypothetical cytosolic protein SYN_03572 1 None None None 85859317 Common - adenylate kinase / nucleoside-diphosphate kinase SYN_02538 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 85859872 Nonpathogen - hypothetical cytosolic protein SYN_00487 1 None None None 85859711 Common - cytochrome d ubiquinol oxidase subunit II SYN_01975 153 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 85859954 Common - pyruvate synthase gamma chain SYN_00693 68 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 85859517 Nonpathogen - hypothetical membrane protein SYN_01859 2 None None None 85860493 Nonpathogen - hypothetical protein SYN_03116 6 None None None 85860107 Common - hypothetical cytosolic protein SYN_03712 8 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 85858486 Common - LemA family protein SYN_00535 131 COG1704 LemA, Uncharacterized conserved protein Function unknown 85858162 Common - LSU ribosomal protein L6P SYN_01590 243 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 85860627 Common - deoxyguanosinetriphosphate triphosphohydrolase SYN_01066 159 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 85859480 Nonpathogen - hypothetical membrane protein SYN_01820 1 None None None 85859608 Common - SAM-dependent methyltransferase SYN_02009 37 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 85859340 Common groEL chaperonin GroEL SYN_03223 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 85860854 Common - hypothetical cytosolic protein SYN_01673 22 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 85860620 Common - tonB protein SYN_01059 30 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 85858632 Common - cell wall-associated hydrolase SYN_01955 24 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 85859213 Common - tetratricopeptide repeat domain with UbiE methylase SYN_02802 56 COG4627 COG4627, Uncharacterized protein conserved in bacteria Function unknown 85860683 Common - export ABC transporter ATP-binding protein SYN_00242 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 85858764 Common - helix-turn-helix DNA binding protein SYN_02736 26 None None None 85859457 Common - DNA polymerase III alpha subunit SYN_00896 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 85858507 Common - PTS system mannose/fructose/sorbose family IID component protein SYN_01727 41 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 85860476 Common - glucose-1-phosphate cytidylyltransferase SYN_02649 157 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 85859605 Nonpathogen - hypothetical cytosolic protein SYN_02011 1 None None None 85860042 Common - gluconate kinase SYN_00043 59 COG2187 COG2187, Uncharacterized protein conserved in bacteria Function unknown 85859867 Common - molybdopterin-guanine dinucleotide biosynthesis protein A SYN_00482 112 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 85859644 Nonpathogen - hypothetical membrane protein SYN_03612 1 None None None 85858336 Common - anti-sigma F factor antagonist SYN_02356 75 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 85860143 Nonpathogen - hypothetical cytosolic protein SYN_03719 1 None None None 85858753 Nonpathogen - hypothetical cytosolic protein SYN_02745 1 None None None 85859074 Common - adenylosuccinate lyase SYN_00426 236 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 85860284 Common - ferric uptake regulator family protein SYN_02524 194 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 85860899 Common carB carbamoyl phosphate synthase large subunit SYN_01625 235 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 85858057 Common - signal transduction histidine kinase SYN_02576 226 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 85859082 Common - hypothetical membrane protein SYN_00418 83 COG2928 COG2928, Uncharacterized conserved protein Function unknown 85858200 Nonpathogen - hypothetical cytosolic protein SYN_00518 1 None None None 85859943 Common - phosphohydrolase SYN_00684 20 COG4119 COG4119, Predicted NTP pyrophosphohydrolase DNA replication, recombination, and repair / General function prediction only 85860391 Nonpathogen - hypothetical cytosolic protein SYN_01170 2 None None None 85857910 Common - bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein SYN_00176 181 COG0646 MetH, Methionine synthase I (cobalamin-dependent), methyltransferase domain Amino acid transport and metabolism 85858416 Common - heme insertion protein SYN_03385 112 COG4137 COG4137, ABC-type uncharacterized transport system, permease component General function prediction only 85860452 Nonpathogen - hypothetical cytosolic protein SYN_02673 1 None None None 85858241 Common - undecaprenyl-phosphate galactosephosphotransferase SYN_01131 184 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 85860206 Common - hydrogenase isoenzymes formation protein SYN_00598 109 COG0409 HypD, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 85859562 Nonpathogen - hypothetical cytosolic protein SYN_01905 2 None None None 85858032 Common - ribose 5-phosphate isomerase SYN_02366 128 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 85859120 Common - ATPase SYN_01511 61 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 85859335 Common - ABC-type phosphate transport system, permease component SYN_00058 226 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 85860564 Nonpathogen - hypothetical membrane protein SYN_00290 1 None None None 85859768 Nonpathogen - hypothetical protein SYN_03640 1 COG4982 COG4982, 3-oxoacyl- acyl-carrier protein 85857966 Common - cation transport ATPase SYN_02218 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 85860239 Common - hypothetical protein SYN_01582 8 None None None 85859093 Common - SSU ribosomal protein S1P SYN_03197 217 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 85860121 Nonpathogen - hypothetical protein SYN_03714 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 85860150 Common - branched-chain amino acid transport system permease protein SYN_00788 164 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 85858093 Common - 23S rRNA methyltransferase SYN_01444 206 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 85860470 Common - ABC-type polysaccharide/polyol phosphate export systems, permease component SYN_02655 107 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 85860189 Common - NAD(FAD)-utilizing dehydrogenases SYN_00579 79 COG2509 COG2509, Uncharacterized FAD-dependent dehydrogenases General function prediction only 85858234 Nonpathogen - hypothetical cytosolic protein SYN_01138 1 None None None 85858010 Common - ABC-type tungstate transport system, solute-binding protein SYN_00836 62 COG2998 TupB, ABC-type tungstate transport system, permease component Coenzyme metabolism 85860952 Nonpathogen - hypothetical cytosolic protein SYN_03847 1 None None None 85858992 Common - hypothetical protein SYN_01008 45 COG3735 COG3735, Uncharacterized protein conserved in bacteria Function unknown 85858955 Nonpathogen - acetyltransferase (GNAT) family protein SYN_00562 6 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 85858673 Nonpathogen - hypothetical protein SYN_02921 1 None None None 85859656 Common - prephenate dehydrogenase SYN_01933 66 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 85859761 Nonpathogen - hypothetical cytosolic protein SYN_03638 1 None None None 85859510 Common - snf2-related protein with C-terminal Helicase SYN_01852 214 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 85860035 Nonpathogen - hypothetical membrane protein SYN_00050 3 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 85860376 Common - iron-sulfur cluster assembly/repair protein SYN_01185 237 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 85859240 Common - heterodisulfide reductase, subunit A SYN_03215 45 COG1148 HdrA, Heterodisulfide reductase, subunit A and related polyferredoxins Energy production and conversion 85858520 Common - UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase SYN_01740 212 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 85858184 Nonpathogen - hypothetical membrane protein SYN_03321 1 None None None 85860775 Nonpathogen - hypothetical cytosolic protein SYN_00346 2 None None None 85858930 Nonpathogen - hypothetical cytosolic protein SYN_02144 1 None None None 85859780 Nonpathogen - hypothetical cytosolic protein SYN_02879 1 None None None 85860017 Nonpathogen - hypothetical cytosolic protein SYN_03694 1 None None None 85860757 Nonpathogen - hypothetical cytosolic protein SYN_00364 1 None None None 85857927 Common - fumarate hydratase beta subunit SYN_00158 148 COG1838 FumA, Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain Energy production and conversion 85857880 Nonpathogen - hypothetical cytosolic protein SYN_00012 2 None None None 85858552 Common - gamma-glutamyl kinase SYN_01350 190 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 85859234 Nonpathogen - hypothetical membrane protein SYN_01379 1 None None None 85860905 Common - phosphoesterase SYN_01619 108 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 85859813 Common - lipoprotein SYN_00999 182 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 85860366 Common - coenzyme F390 synthetase / phenylacetate-coenzyme A ligase SYN_01195 125 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 85858963 Common - acetylornithine aminotransferase / Succinyldiaminopimelate aminotransferase SYN_00570 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 85858070 Common - proton/sodium-glutamate symport protein SYN_01421 162 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 85858888 Common - predicted endonuclease containing a URI domain SYN_00393 84 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 85859397 Common - membrane-bound serine protease SYN_02179 64 COG1030 NfeD, Membrane-bound serine protease (ClpP class) Posttranslational modification, protein turnover, chaperones 85859345 Nonpathogen - hypothetical cytosolic protein SYN_03559 1 None None None 85859528 Common - hypothetical cytosolic protein SYN_01870 4 None None None 85860525 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase SYN_01793 210 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 85858979 Common - two-component response regulator SYN_01019 220 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 85858549 Common - spermidine synthase SYN_01347 111 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 85859437 Common - membrane metalloprotease SYN_00915 214 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 85860973 Common - fog:ggdef domain membrane protein SYN_02092 134 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 85857906 Common - zn-dependent protease with chaperone function SYN_03230 69 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 85859010 Nonpathogen - hypothetical cytosolic protein SYN_03515 1 None None None 85860568 Common - DNA polymerase IV SYN_00286 93 COG1796 POL4, DNA polymerase IV (family X) DNA replication, recombination, and repair 85860754 Common - sulfate transport ATP-binding protein SYN_00367 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 85859789 Nonpathogen - hypothetical membrane protein SYN_02887 4 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 85860426 Common - aminotransferase SYN_02699 230 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 85859128 Nonpathogen - hypothetical membrane protein SYN_01503 1 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 85860646 Nonpathogen - hypothetical cytosolic protein SYN_00865 1 None None None 85859820 Common - methyltransferase SYN_01006 147 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 85859021 Common - response regulator with a winged-helix DNA-binding domain SYN_00981 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 85859242 Common - hypothetical cytosolic protein SYN_03543 56 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 85860175 Common - signal recognition particle GTPase SYN_00996 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 85858555 Common - LSU ribosomal protein L21P SYN_01353 215 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 85858084 Common - transposase SYN_03249 69 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 85858527 Common - UDP-N-acetylmuramate--alanine ligase SYN_01747 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 85860985 Common - phosphate butyryltransferase SYN_02080 61 COG0280 Pta, Phosphotransacetylase Energy production and conversion 85860338 Nonpathogen - hypothetical cytosolic protein SYN_03007 1 None None None 85859491 Common - hypothetical cytosolic protein SYN_01832 12 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 85860906 Nonpathogen - hypothetical membrane protein SYN_01618 1 None None None 85860029 Common - hypothetical membrane protein SYN_00762 6 None None None 85858126 Nonpathogen - hypothetical cytosolic protein SYN_01283 1 None None None 85858844 Nonpathogen - hypothetical cytosolic protein SYN_03063 1 None None None 85859982 Common - lactoylglutathione lyase SYN_00718 22 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 85858639 Nonpathogen - hypothetical cytosolic protein SYN_03439 7 COG0432 COG0432, Uncharacterized conserved protein Function unknown 85860234 Nonpathogen - hypothetical membrane protein SYN_01586 1 None None None 85859671 Common - hypothetical membrane protein SYN_02762 66 COG1624 COG1624, Uncharacterized conserved protein Function unknown 85860094 Common - outer membrane protein SYN_01569 10 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 85858303 Common - hypothetical cytosolic protein SYN_02612 20 None None None 85858586 Common - holliday junction DNA helicase SYN_02972 211 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 85861005 Common - zinc metalloprotease SYN_02061 154 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 85858891 Common - nudix domain protein SYN_00395 75 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 85859174 Common - flagellar hook capping protein SYN_02840 122 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 85859873 Nonpathogen - hypothetical protein SYN_03660 1 None None None 85859290 Common - oligopeptide transport ATP-binding protein SYN_02171 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 85859036 Common - chemotaxis protein SYN_00967 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 85860165 Common - ABC transporter ATP-binding protein SYN_00774 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 85859165 Common - tetratricopeptide repeat domain SYN_02849 56 COG4785 NlpI, Lipoprotein NlpI, contains TPR repeats General function prediction only 85860698 Nonpathogen - methyl-viologen-reducing hydrogenase, delta subunit SYN_02424 28 COG1908 FrhD, Coenzyme F420-reducing hydrogenase, delta subunit Energy production and conversion 85858004 Nonpathogen - hypothetical cytosolic protein SYN_00841 4 None None None 85859660 Common - shikimate 5-dehydrogenase SYN_01937 226 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 85860549 Common - thioredoxin-like protein SYN_03787 15 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 85859262 Common - aldehyde dehydrogenase (ferredoxin) SYN_00261 57 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 85857917 Common - aminotransferase, class I and II SYN_00168 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 85860332 Common - tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase SYN_01256 218 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 85858984 Common - single-stranded nucleic acid binding domain SYN_01015 63 COG1847 Jag, Predicted RNA-binding protein General function prediction only 85859487 Common - SNF2-related:Helicase, C-terminal:type III restriction enzyme SYN_01827 98 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 85859542 Nonpathogen - hypothetical cytosolic protein SYN_01885 2 None None None 85858914 Common - 3-oxoacyl- reductase SYN_02127 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 85858754 Nonpathogen - hypothetical cytosolic protein SYN_02746 6 None None None 85860069 Common - metal-dependent hydrolase of the TIM-barrel fold SYN_01545 27 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 85860297 Common - macrolide-efflux protein SYN_01220 158 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 85860245 Nonpathogen - hypothetical cytosolic protein SYN_03738 1 None None None 85858517 Common - S-adenosyl-methyltransferase mraW SYN_01737 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 85860587 Common - hypothetical cytosolic protein SYN_02476 14 None None None 85858896 Common - transcriptional regulator TetR family SYN_02108 97 COG1309 AcrR, Transcriptional regulator Transcription 85859089 Common - pyruvate formate-lyase activating enzyme SYN_03523 88 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 85858922 Nonpathogen - hypothetical cytosolic protein SYN_02135 1 None None None 85860458 Common - alpha-D-QuiNAc alpha-1,3-galactosyltransferase SYN_02667 208 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 85857973 Common - ABC-type phosphate transport system, ATPase component SYN_02224 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 85858485 Nonpathogen - hypothetical cytosolic protein SYN_00536 4 None None None 85859369 Common - hypothetical cytosolic protein SYN_02774 52 COG5495 COG5495, Uncharacterized conserved protein Function unknown 85858117 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase SYN_01275 197 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 85858809 Nonpathogen - hypothetical cytosolic protein SYN_01462 1 None None None 85858343 Common - hypothetical membrane protein SYN_02349 4 None None None 85859066 Nonpathogen - hypothetical cytosolic protein SYN_00937 1 None None None 85859309 Common - outer membrane protein SYN_02546 62 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 85860969 Common - F0F1-type ATP synthase, beta subunit SYN_02096 245 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 85860489 Common - electron transfer flavoprotein beta-subunit SYN_02636 153 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 85859462 Common - cofactor-independent phosphoglycerate mutase SYN_00891 61 COG3635 COG3635, Predicted phosphoglycerate mutase, AP superfamily Carbohydrate transport and metabolism 85857922 Nonpathogen - hypothetical cytosolic protein SYN_03270 1 None None None 85859801 Common - dTDP-4-dehydrorhamnose reductase SYN_01394 174 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 85859104 Common - endonuclease IV SYN_01340 34 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 85858900 Nonpathogen - hypothetical cytosolic protein SYN_02113 1 None None None 85858381 Common - L-alanyl-D-glutamate peptidase SYN_02309 9 None None None 85859299 Nonpathogen - hypothetical membrane protein SYN_03222 1 None None None 85860363 Common - indolepyruvate oxidoreductase subunit SYN_01198 76 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 85860979 Common - phosphoenolpyruvate carboxykinase SYN_02086 50 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 85859844 Common - general secretion pathway protein G SYN_00459 67 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 85860728 Nonpathogen - hypothetical cytosolic protein SYN_02395 1 None None None 85857945 Common - aldehyde:ferredoxin oxidoreductase SYN_00140 57 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 85860468 Common - transposase SYN_02657 40 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 85857887 Common - hypothetical cytosolic protein SYN_00020 28 COG4642 COG4642, Uncharacterized protein conserved in bacteria Function unknown 85859634 Nonpathogen - hypothetical membrane protein SYN_02453 1 None None None 85859690 Common - transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains SYN_01090 185 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 85858567 Common - phosphoribosylaminoimidazole carboxylase carboxyltransferase subunit SYN_02442 226 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 85859631 Common - 1-deoxy-D-xylulose 5-phosphate synthase SYN_02456 229 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 85857956 Nonpathogen - hypothetical cytosolic protein SYN_02207 1 None None None 85859183 Common - flagellar biosynthesis pathway component SYN_02832 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 85859198 Common - flagellar L-ring protein SYN_02817 99 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 85858442 Nonpathogen - hypothetical cytosolic protein SYN_02248 5 COG3337 COG3337, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 85858529 Common - cell division protein SYN_03045 56 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 85859579 Common - Sua5/YciO/YrdC/YwlC family protein SYN_02195 233 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 85860343 Common - hypothetical cytosolic protein SYN_00859 7 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 85859531 Common - hypothetical protein SYN_01873 12 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 85860196 Common - hypothetical membrane protein SYN_00586 8 COG5336 COG5336, Uncharacterized protein conserved in bacteria Function unknown 85858436 Common - hypothetical cytosolic protein SYN_02254 19 None None None 85859918 Common - glutamate decarboxylase SYN_00664 107 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 85859302 Common - exodeoxyribonuclease V gamma chain SYN_02553 66 COG1330 RecC, Exonuclease V gamma subunit DNA replication, recombination, and repair 85860917 Common - hypothetical membrane protein SYN_03077 12 COG5652 COG5652, Predicted integral membrane protein Function unknown 85860230 Nonpathogen - hypothetical cytosolic protein SYN_01588 1 None None None 85860847 Common - acetyl-CoA acetyltransferase SYN_01681 156 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 85859852 Common - hypothetical cytosolic protein SYN_00467 15 COG1633 COG1633, Uncharacterized conserved protein Function unknown 85860320 Common - calcineurin-like phosphoesterase SYN_01244 22 COG2129 COG2129, Predicted phosphoesterases, related to the Icc protein General function prediction only 85857985 Common - ferredoxin SYN_00628 80 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 85859180 Common fliP flagellar biosynthesis protein FliP SYN_02835 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 85860318 Common - glutamate dehydrogenase SYN_01242 177 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 85859380 Common - ATP-dependent Clp protease proteolytic subunit SYN_02785 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 85860062 Common - universal stress protein family SYN_01538 138 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 85858543 Nonpathogen - hypothetical membrane protein SYN_03130 6 COG1584 COG1584, Predicted membrane protein Function unknown 85860405 Nonpathogen - hypothetical cytosolic protein SYN_00080 2 None None None 85858472 Common - ATP synthase B chain, sodium ion specific SYN_00549 16 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 85860590 Nonpathogen - exonuclease SYN_02479 1 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 85860797 Common - zn-dependent hydrolases, including glyoxylases SYN_00320 102 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 85860010 Common - moxR protein SYN_00744 174 COG0714 COG0714, MoxR-like ATPases General function prediction only 85860795 Common - membrane endopeptidase, M50 family SYN_00323 83 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 85860325 Common - protein required for formate dehydrogenase activity SYN_01250 137 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 85860579 Nonpathogen - hypothetical cytosolic protein SYN_03795 7 None None None 85859549 Nonpathogen - hypothetical cytosolic protein SYN_01892 1 None None None 85859328 Common - malate/L-lactate dehydrogenase SYN_02526 67 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 85859572 Common - DNA integration/recombination/inversion protein SYN_01916 104 COG0582 XerC, Integrase DNA replication, recombination, and repair 85859311 Common - universal stress protein family SYN_02544 137 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 85859389 Common - phoH protein SYN_02794 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 85858880 Nonpathogen - hypothetical membrane protein SYN_01311 1 COG3511 PlcC, Phospholipase C Cell envelope biogenesis, outer membrane 85860275 Nonpathogen - hypothetical cytosolic protein SYN_02515 1 None None None 85858496 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase SYN_01716 209 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 85859177 Common - flagellar motor switch protein SYN_02837 111 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 85858964 Common - alanine racemase, N-terminal domain protein SYN_00571 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 85858414 Common - ribosomal protein L11 methyltransferase SYN_02277 182 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 85860219 Common - hydrolase of the alpha/beta superfamily N SYN_00611 54 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 85859550 Nonpathogen - hypothetical cytosolic protein SYN_03586 1 None None None 85860414 Nonpathogen - hypothetical membrane protein SYN_00089 1 None None None 85859983 Common - hypothetical cytosolic protein SYN_00719 113 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 85857933 Common - NADH:ubiquinone oxidoreductase, NADH-binding subunit SYN_00152 187 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 85858637 Common - acyl-CoA synthetase SYN_01949 142 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 85859003 Common - sensory domain linked to a LuxR family regulatory protein SYN_00112 141 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 85860689 Common - hydrolase or acyltransferase SYN_02434 159 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 85858681 Common - branched-chain amino acid aminotransferase SYN_03155 190 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 85860817 Common - acetolactate synthase small subunit SYN_01712 187 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 85859879 Nonpathogen - hypothetical cytosolic protein SYN_00492 3 None None None 85860305 Nonpathogen - hypothetical cytosolic protein SYN_01227 1 None None None 85860354 Common - bacterial peptide Chain Release Factor 3 (RF-3) SYN_00848 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 85858321 Common - 4Fe-4S protein SYN_00260 21 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 85860227 Nonpathogen - hypothetical cytosolic protein SYN_03019 1 None None None 85860408 Common - metal-dependent amidase/aminoacylase/carboxypeptidase SYN_00083 167 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 85860864 Common - sodium-translocating NADH-quinone reductase subunit C SYN_01662 5 COG4659 RnfG, Predicted NADH:ubiquinone oxidoreductase, subunit RnfG Energy production and conversion 85858585 Common - crossover junction endodeoxyribonuclease SYN_02973 198 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 85859220 Common - hypothetical cytosolic protein SYN_03209 4 None None None 85858781 Common - HD domain / HAMP domain protein SYN_02721 131 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 85860550 Nonpathogen - thiol:disulfide interchange protein SYN_03115 4 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 85857964 Common - signal transduction histidine kinase SYN_02215 223 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 85858718 Common - tolR protein SYN_00186 129 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 85858937 Common - Hydrogenase transcriptional regulatory protein SYN_01373 203 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 85859012 Common - phage replication protein SYN_00118 4 None None None 85860716 Nonpathogen - hypothetical membrane protein SYN_02406 1 None None None 85860339 Nonpathogen - hypothetical cytosolic protein SYN_00863 1 None None None 85860137 Common - ferridoxin SYN_00800 91 COG1148 HdrA, Heterodisulfide reductase, subunit A and related polyferredoxins Energy production and conversion 85859687 Common - acyl-CoA hydrolase SYN_01088 26 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 85859619 Common - multimodular transpeptidase-transglycosylase SYN_01998 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 85858785 Nonpathogen - hypothetical cytosolic protein SYN_02717 1 None None None 85860223 Nonpathogen - hypothetical cytosolic protein SYN_00617 1 None None None 85858179 Nonpathogen - hypothetical cytosolic protein SYN_02984 1 None None None 85860604 Common - hypothetical cytosolic protein SYN_01044 98 COG1720 COG1720, Uncharacterized conserved protein Function unknown 85860918 Common - glycogen phosphorylase SYN_00231 142 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 85857998 Common - molybdopterin converting factor, large subunit SYN_01958 33 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 85858664 Common - hypothetical cytosolic protein SYN_02913 2 None None None 85858147 Common - LSU ribosomal protein L4 SYN_00986 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 85859200 Nonpathogen - peptidoglycan hydrolase SYN_02815 6 COG3951 COG3951, Rod binding protein Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 85860440 Common - glycosyltransferase SYN_02685 176 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 85858749 Nonpathogen - hypothetical cytosolic protein SYN_02750 6 None None None 85859144 Common - transposase SYN_01487 5 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 85859659 Common - 3-phosphoshikimate-1-carboxyvinyltransferase SYN_01936 228 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 85860070 Nonpathogen - hypothetical cytosolic protein SYN_01546 1 None None None 85858121 Common - guanylate kinase SYN_01279 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 85858531 Common - cell division protein FtsZ SYN_00437 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 85859314 Common - membrane spanning protein ribonuclease BN-like family SYN_02541 107 COG1295 Rbn, Predicted membrane protein Function unknown 85858102 Common - peptide methionine sulfoxide reductase SYN_01261 206 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 85857893 Common - chaperone protein SYN_00026 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 85860374 Common - iron-sulfur cluster and nucleotide-binding protein SYN_01187 46 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 85859057 Common - ABC transporter ATP-binding protein SYN_00946 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 85859612 Common - response regulator protein with GGDEF domain SYN_02005 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 85860116 Common - glycosyltransferase SYN_00821 186 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 85860213 Common - formate dehydrogenase, cytochrome b subunit SYN_00605 67 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 85858371 Nonpathogen - hypothetical cytosolic protein SYN_03369 1 None None None 85860963 Common - F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type proton-ATPase, subunit K SYN_02102 86 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 85860932 Common - hypothetical cytosolic protein SYN_03842 37 COG2191 COG2191, Formylmethanofuran dehydrogenase subunit E Energy production and conversion 85858929 Common - Zn-dependent hydrolases SYN_02143 209 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 85859448 Common - GTP pyrophosphokinase / guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase SYN_00904 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 85860528 Common - LSU ribosomal protein L31P SYN_01796 184 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 85858596 Common - hypothetical cytosolic protein SYN_02961 58 COG0391 COG0391, Uncharacterized conserved protein Function unknown 85858294 Common - aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A SYN_02603 215 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 85859557 Common - transposase SYN_01900 83 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 85859592 Common - carboxy-terminal processing protease precursor SYN_02024 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 85858028 Common - riboflavin synthase subunit alpha SYN_02370 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 85858973 Nonpathogen - hypothetical cytosolic protein SYN_01024 1 None None None 85859949 Common - hypothetical membrane protein SYN_03100 11 None None None 85858378 Common - hypothetical cytosolic protein SYN_02313 14 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 85858353 Common - transcriptional regulator GerE family SYN_02339 108 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 85860955 Common - 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase SYN_01300 187 COG2876 AroA, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 85859304 Common - exodeoxyribonuclease V alpha chain SYN_02551 122 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 85857950 Nonpathogen - hypothetical cytosolic protein SYN_03276 1 None None None 85858799 Common - cell division inhibitor SYN_02706 82 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 85858790 Common - response regulator containing sigma 54 interaction domain SYN_02713 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 85860482 Common - long-chain-fatty-acid--CoA ligase SYN_02643 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 85858650 Nonpathogen - hypothetical cytosolic protein SYN_03152 1 None None None 85858715 Common - protein translation Elongation Factor P (EF-P) SYN_00183 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 85858729 Common - rmuC family protein SYN_00197 130 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 85858708 Common - hypothetical cytosolic protein SYN_00137 42 COG2835 COG2835, Uncharacterized conserved protein Function unknown 85857958 Common - metal-dependent hydrolase SYN_02209 144 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 85858423 Common - radical SAM superfamily protein SYN_02268 158 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 85858691 Nonpathogen - hypothetical cytosolic protein SYN_03158 1 None None None 85860655 Nonpathogen - hypothetical cytosolic protein SYN_00873 1 None None None 85858504 Common - DNA-binding protein HU SYN_01724 205 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 85858045 Common - acyl carrier protein SYN_02564 15 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 85859350 Nonpathogen - hypothetical membrane protein SYN_03561 1 None None None 85860725 Common - ferric uptake regulatory protein SYN_02397 186 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 85858670 Common - ferridoxin SYN_02918 68 COG0778 NfnB, Nitroreductase Energy production and conversion 85859286 Nonpathogen - hypothetical cytosolic protein SYN_02168 1 None None None 85859068 Common - acetyl-CoA CoA transferase / acetyltransferase SYN_00935 143 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 85858066 Common - acyl-CoA dehydrogenase, medium-chain specific SYN_02586 164 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 85858250 Nonpathogen - hypothetical cytosolic protein SYN_01123 1 None None None 85858055 Common - hydrolase, isochorismatase family SYN_02574 97 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 85859940 Nonpathogen - hypothetical cytosolic protein SYN_00681 1 None None None 85858599 Common - 6-phosphogluconolactonase/glucosamine-6-phosphate isomerase/deaminase SYN_02958 78 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 85858734 Common - universal stress protein family SYN_02484 6 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 85860044 Common - mazG-like domain protein SYN_00041 158 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 85858285 Common - transcriptional regulator GerE family SYN_02593 155 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 85858943 Common - hypothetical membrane protein SYN_01367 48 COG1811 COG1811, Uncharacterized membrane protein, possible Na+ channel or pump General function prediction only 85858211 Nonpathogen - hypothetical cytosolic protein SYN_01161 1 None None None 85858365 Common - AAA-superfamily of ATPases protein SYN_02326 14 COG2842 COG2842, Uncharacterized ATPase, putative transposase General function prediction only 85859410 Common - NAD-dependent DNA ligase SYN_02935 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 85858261 Common - UDP-N-acetylglucosamine 4-epimerase SYN_01112 232 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 85860803 Common - universal stress protein family SYN_00314 56 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 85858005 Common - hypothetical cytosolic protein SYN_00840 13 COG1571 COG1571, Predicted DNA-binding protein containing a Zn-ribbon domain General function prediction only 85860136 Nonpathogen - hypothetical cytosolic protein SYN_00802 1 None None None 85860872 Common - putative enoyl-CoA hydratase SYN_01653 178 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 85857866 Common - succinyl-CoA synthetase, alpha subunit SYN_00001 206 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 85858453 Common - hypothetical cytosolic protein SYN_02240 16 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 85858207 Nonpathogen - hypothetical cytosolic protein SYN_00523 1 None None None 85859739 Common - sigma-54-dependent transcriptional activator SYN_01919 164 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 85858575 Common - hypothetical cytosolic protein SYN_02981 11 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 85860825 Common - hypothetical cytosolic protein SYN_01703 23 COG2121 COG2121, Uncharacterized protein conserved in bacteria Function unknown 85858829 Nonpathogen - hypothetical cytosolic protein SYN_01484 1 None None None 85858387 Common - mu-like prophage Flumu protein gp27 SYN_02305 13 None None None 85859819 Nonpathogen - hypothetical cytosolic protein SYN_03652 1 None None None 85859468 Common - 6-phosphofructokinase SYN_00886 161 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 85860990 Common - acriflavin resistance periplasmic protein SYN_02075 138 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 85860935 Common - ABC-type Fe3+-hydroxamate transport system, periplasmic component SYN_00215 90 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 85859132 Common - flp pilus assembly protein SYN_01499 75 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 85859167 Common - acetyltransferase GNAT family SYN_02847 208 COG0456 RimI, Acetyltransferases General function prediction only 85859622 Common - export ABC transporter permease protein SYN_01995 182 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 85860079 Common - general secretory pathway protein K SYN_01554 6 COG3156 PulK, Type II secretory pathway, component PulK Intracellular trafficking and secretion 85858197 Common - TrpR binding protein WrbA SYN_00514 119 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 85858645 Nonpathogen - hypothetical cytosolic protein SYN_01750 1 None None None 85859501 Common - hypothetical cytosolic protein SYN_01843 7 None None None 85859266 Common - tRNA 2-methylthioadenosine synthase SYN_02149 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 85859793 Common - fibronectin type III domain containing protein SYN_02891 27 COG4380 COG4380, Uncharacterized protein conserved in bacteria Function unknown 85857925 Common - recombination protein SYN_03272 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 85860631 Common - 4-alpha-glucanotransferase SYN_01069 120 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 85859218 Common - SMF family protein involved in DNA uptake SYN_02797 210 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 85859825 Common - thiS family protein SYN_00441 25 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 85859479 Common - hypothetical cytosolic protein SYN_01819 19 None None None 85858693 Common - response regulator containing a CheY-like receiver domain and an HD-GYP domain SYN_00875 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 85859406 Common - adenylate kinase / nucleoside-diphosphate kinase SYN_02188 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 85859046 Nonpathogen - hypothetical cytosolic protein SYN_00957 1 None None None 85860055 Common - uracil phosphoribosyltransferase / pyrimidine operon regulatory protein SYN_03702 123 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 85860533 Common - coproporphyrinogen III oxidase SYN_01802 202 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 85859427 Nonpathogen - hypothetical cytosolic protein SYN_03571 1 None None None 85860198 Common - ATP synthase A chain SYN_00588 201 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 85858077 Nonpathogen - hypothetical membrane protein SYN_03296 1 None None None 85860030 Nonpathogen - hypothetical cytosolic protein SYN_03697 1 None None None 85859117 Common - ATPase SYN_01514 59 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 85858153 Common rplP 50S ribosomal protein L16 SYN_00992 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 85860262 Nonpathogen - ompA-like protein SYN_02503 4 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 85858407 Common - mu-like prophage Flumu protein gp47 SYN_02285 16 COG3299 XkdT, Uncharacterized homolog of phage Mu protein gp47 Function unknown 85858394 Common - mu-like prophage major head subunit SYN_02298 17 COG4397 COG4397, Mu-like prophage major head subunit gpT General function prediction only 85858274 Common - lipopolysaccharide N-acetylglucosaminyltransferase SYN_01099 219 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 85858372 Nonpathogen - hypothetical cytosolic protein SYN_03039 1 None None None 85859835 Nonpathogen - hypothetical membrane protein SYN_00451 1 None None None 85860943 Common - phosphate/sulphate permease SYN_03078 140 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 85859364 Common - Sodium driven multidrug efflux pump SYN_01968 171 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 85859882 Common - type I restriction-modification system specificity subunit SYN_00495 105 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 85860110 Common - perosamine synthetase SYN_00827 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 85858616 Nonpathogen - hypothetical membrane protein SYN_03432 1 None None None 85860015 Common - hypothetical membrane protein SYN_00749 19 None None None 85860780 Common - arsenical-resistance protein acr3 SYN_00340 130 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 85859680 Common - pyridoxamine phosphate oxidase SYN_03000 12 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 85860617 Common - iron(III) dicitrate-binding protein SYN_01056 101 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 85859581 Common - pyrroline-5-carboxylate reductase SYN_02197 216 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 85860202 Common - hypothetical membrane protein SYN_00592 4 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 85858022 Common - SSU ribosomal protein S20 SYN_02376 193 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 85859746 Common - cell wall-associated hydrolase SYN_01408 160 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 85858248 Common - UDP-glucose 4-epimerase SYN_01125 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 85859159 Common - hypothetical protein SYN_02855 16 None None None 85858518 Nonpathogen - hypothetical membrane protein SYN_01738 8 COG3116 FtsL, Cell division protein Cell division and chromosome partitioning 85859211 Common - flagellin SYN_02804 122 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 85858722 Common - tol system periplasmic component SYN_00190 115 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 85859759 Common - 3-hydroxyacyl-CoA dehydrogenase SYN_01310 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 85858623 Common - exonuclease SYN_00201 100 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 85860665 Nonpathogen - hypothetical cytosolic protein SYN_02625 7 None None None 85859400 Common - phosphoserine phosphatase SYN_02182 17 COG4359 COG4359, Uncharacterized conserved protein Function unknown 85860007 Common - transglutaminase-like enzymes, putative cysteine proteases SYN_00741 86 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 85858299 Common - hypothetical cytosolic protein SYN_02608 11 None None None 85859725 Common - RNA polymerase sigma-B factor SYN_00639 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 85858095 Common - transketolase SYN_01447 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 85860830 Common - 3-oxoacyl-[acyl-carrier-protein] synthase III SYN_01698 201 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 85859728 Common - hypothetical cytosolic protein SYN_03047 13 None None None 85860437 Common - UDP-bacillosamine synthetase SYN_02688 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 85860191 Common - peptide chain release factor SYN_00581 204 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 85859296 Common - cytosine deaminase and related metal-dependent hydrolase SYN_01572 172 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 85860383 Nonpathogen - response regulator receiver domain SYN_01178 4 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 85860739 Common - pyrophosphorylase ModD SYN_00382 171 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 85859848 Common - methyltransferase SYN_00463 24 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 85860448 Common - zinc-binding dehydrogenase SYN_02677 164 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 85859730 Common - ribose-phosphate pyrophosphokinase SYN_02767 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 85859190 Nonpathogen - hypothetical cytosolic protein SYN_02824 2 None None None 85858662 Common - DNA helicase SYN_02909 84 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 85860760 Common - hypothetical membrane protein SYN_00361 38 COG0392 COG0392, Predicted integral membrane protein Function unknown 85860667 Common - peptidoglycan-specific endopeptidase, M23 family SYN_02623 189 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 85860790 Common - ATP-dependent protease subunit SYN_00329 103 COG0714 COG0714, MoxR-like ATPases General function prediction only 85859367 Common - peptidylprolyl isomerase SYN_03141 157 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 85860123 Nonpathogen - tfp pilus assembly protein, major pilin SYN_00814 1 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 85860187 Nonpathogen - hypothetical cytosolic protein SYN_03728 1 None None None 85860159 Common - Chain length determinant protein, Wzz-like protein SYN_00780 109 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 85858537 Common - chemotaxis protein SYN_00431 223 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 85858944 Common - calcineurin-like phosphoesterase SYN_01366 75 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 85860100 Nonpathogen - sec-independent protein translocase protein SYN_00926 22 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 85860915 Common - modulator of glutathione-dependent potassium efflux system SYN_01609 56 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 85858306 Nonpathogen - hypothetical cytosolic protein SYN_00246 1 None None None 85858050 Common - dethiobiotin synthetase SYN_02569 147 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 85860286 Common - ribonucleoside-diphosphate reductase alpha chain SYN_01209 223 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 85860995 Common - ABC transporter permease protein SYN_02070 150 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 85859766 Nonpathogen - hypothetical membrane protein SYN_01304 1 None None None 85857891 Common - ABC transporter ATP-binding protein SYN_00024 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 85860710 Nonpathogen - hypothetical cytosolic protein SYN_03812 1 None None None 85858998 Nonpathogen - hypothetical cytosolic protein SYN_00108 1 None None None 85860890 Common - sigma-54 dependent transcription regulator SYN_01635 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 85859560 Common - hypothetical cytosolic protein SYN_01903 35 COG2152 COG2152, Predicted glycosylase Carbohydrate transport and metabolism 85858155 Common - LSU ribosomal protein L29P SYN_00993 95 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 85858256 Nonpathogen - hypothetical membrane protein SYN_01117 3 None None None 85860172 Common - 16S rRNA processing protein SYN_00767 165 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 85859715 Common - methylmalonyl CoA epimerase SYN_01971 56 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 85859031 Nonpathogen - hypothetical cytosolic protein SYN_00972 1 None None None 85858738 Common - glycogen phosphorylase SYN_02761 150 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 85860566 Common - uncharacterized protein involved in formate dehydrogenase formation SYN_00288 44 COG3058 FdhE, Uncharacterized protein involved in formate dehydrogenase formation Posttranslational modification, protein turnover, chaperones 85859261 Common - transposase SYN_03218 64 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 85859803 Common pgk phosphoglycerate kinase SYN_01396 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 85859305 Nonpathogen - hypothetical cytosolic protein SYN_02550 1 None None None 85860923 Common - signal transduction histidine kinase SYN_00226 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 85858668 Nonpathogen - hypothetical cytosolic protein SYN_02916 3 None None None 85860768 Common - hypothetical protein SYN_00353 21 None None None 85859126 Common - von Willebrand factor type A domain protein SYN_01505 12 COG4655 COG4655, Predicted membrane protein Function unknown 85858953 Common - hypothetical cytosolic protein SYN_00560 8 None None None 85858030 Common - deoxycytidylate deaminase SYN_02368 89 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 85859654 Common - ATPase involved in pili bigenesis SYN_01931 43 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 85860745 Common - hypothetical membrane protein SYN_03817 22 None None None 85860687 Common - type II restriction-modification system methylation subunit SYN_02995 62 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 85858205 Common - phosphoribosylformylglycinamidine synthase SYN_00522 232 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 85857851 Common - RTCB protein SYN_02046 120 COG1690 RtcB, Uncharacterized conserved protein Function unknown 85860378 Common - nifU -like protein involved in Fe-S cluster formation SYN_01183 73 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 85859206 Common - transmembrane protein SYN_02809 41 COG1699 COG1699, Uncharacterized protein conserved in bacteria Function unknown 85859885 Nonpathogen - hypothetical protein SYN_00498 1 None None None 85859862 Common - nickel-responsive regulator SYN_00477 67 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 85858547 Common - phosphatidylethanolamine-binding protein SYN_03131 134 COG1881 COG1881, Phospholipid-binding protein General function prediction only 85860737 Nonpathogen - hypothetical membrane protein SYN_03068 1 None None None 85860527 Common - bacterial peptide chain release factor 1 (rf-1) SYN_01795 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 85859996 Common - gcn5-related N-acetyltransferase SYN_03689 41 None None None 85859435 Common - phosphatidate cytidylyltransferase SYN_00917 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 85858130 Common - hypothetical cytosolic protein SYN_00073 78 COG2078 AMMECR1, Uncharacterized conserved protein Function unknown 85860671 Common - o-succinylbenzoate synthase SYN_02619 45 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 85860519 Common - ribosome-binding factor A SYN_01785 192 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 85857904 Nonpathogen - hypothetical cytosolic protein SYN_00037 4 None None None 85859347 Common - predicted permease SYN_00284 55 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 85858036 Common - zinc finger protein SYN_02362 48 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 85858509 Common - phosphoenolpyruvate-protein phosphotransferase SYN_01729 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 85860301 Common - acetyl-CoA synthetase SYN_01223 212 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 85858590 Common - Zn binding protein SYN_02967 45 COG1579 COG1579, Zn-ribbon protein, possibly nucleic acid-binding General function prediction only 85858688 Common - glycogen synthase /glycogen phosphorylase SYN_00879 151 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 85859952 Common - pyruvate synthase subunit SYN_00691 124 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 85858786 Nonpathogen - hypothetical cytosolic protein SYN_03167 1 None None None 85859601 Nonpathogen - hypothetical cytosolic protein SYN_02015 1 None None None 85858301 Nonpathogen - hypothetical cytosolic protein SYN_02610 1 None None None 85859779 Common - acetyl-CoA synthetase / acetyltransferase (GNAT) family protein SYN_02878 174 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 85858164 Common - SSU ribosomal protein S5P SYN_01592 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 85858367 Common - mu-like prophage protein gp16 SYN_02324 9 COG4382 COG4382, Mu-like prophage protein gp16 Function unknown 85860046 Common - S-adenosylmethionine:tRNA ribosyltransferase-isomerase SYN_00039 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 85859646 Common - nif3-related protein SYN_01923 103 COG0327 COG0327, Uncharacterized conserved protein Function unknown 85858017 Nonpathogen - hypothetical cytosolic protein SYN_02381 1 None None None 85859504 Common - hypothetical cytosolic protein SYN_01846 5 None None None 85858859 Nonpathogen - hypothetical membrane protein SYN_01332 1 None None None 85858540 Common - oxalate/formate antiporter SYN_00428 143 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 85859073 Nonpathogen - hypothetical membrane protein SYN_03194 2 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 85860992 Common - type I secretion outer membrane protein SYN_02073 119 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 85859292 Common - alpha/beta hydrolase family protein SYN_02173 90 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 85858338 Common - phosphatidylglycerophosphatase B -like protein SYN_02354 117 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 85860019 Common - hypothetical RNA binding protein SYN_00752 101 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 85860336 Common - homoserine o-acetyltransferase SYN_01260 133 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 85859455 Common - hypothetical cytosolic protein SYN_00898 21 COG3816 COG3816, Uncharacterized protein conserved in bacteria Function unknown 85860424 Common - tRNA pseudouridine synthase A SYN_02701 233 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 85859019 Common - DNA repair protein RadA SYN_00982 226 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 85859810 Common - hypothetical membrane protein SYN_01402 46 COG4956 COG4956, Integral membrane protein (PIN domain superfamily) General function prediction only 85859865 Common - acyl-CoA dehydrogenase, short-chain specific SYN_00480 165 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 85860974 Nonpathogen - hypothetical membrane protein SYN_02091 1 COG3898 COG3898, Uncharacterized membrane-bound protein Function unknown 85859613 Nonpathogen - hypothetical cytosolic protein SYN_02004 1 None None None 85860114 Common - glycosyltransferase SYN_00823 215 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 85858492 Nonpathogen - hypothetical cytosolic protein SYN_00529 1 None None None 85858804 Common - export ABC transporter permease protein SYN_01456 179 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 85858756 Common - transcriptional regulator SYN_02743 33 COG2378 COG2378, Predicted transcriptional regulator Transcription 85860770 Common - carbon monoxide dehydrogenase corrinoid/iron-sulfur protein gamma subunit SYN_00351 22 COG1456 CdhE, CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein) Energy production and conversion 85859590 Common - two-component response regulator SYN_00099 149 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 85859540 Common - DNA topoisomerase III SYN_01883 11 None None None 85860491 Nonpathogen - hypothetical cytosolic protein SYN_03772 1 None None None 85858830 Common - hypothetical protein SYN_00413 8 None None None 85860268 Nonpathogen - hypothetical cytosolic protein SYN_03010 1 None None None 85857943 Nonpathogen - hypothetical cytosolic protein SYN_00142 1 None None None 85859668 Common - anthranilate phosphoribosyltransferase SYN_01945 220 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 85859080 Common - pantoate--beta-alanine ligase SYN_00420 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 85859232 Common - transposase SYN_01381 35 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 85858775 Nonpathogen - hypothetical membrane protein SYN_02728 2 None None None 85858115 Common - tRNA 2-methylthioadenine synthetase -like protein SYN_01273 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 85860050 Common secF preprotein translocase subunit SecF SYN_01525 219 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 85858037 Common - glutamyl glutaminyl-tRNA synthetase SYN_02557 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 85858079 Common - gerE transcriptional regulator SYN_01430 60 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 85858498 Common - translation initiation factor 3 (IF-3) SYN_01718 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 85859189 Nonpathogen - hypothetical cytosolic protein SYN_02825 3 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 85860465 Common - glycosyltransferase SYN_02660 198 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 85860290 Common - carbamate kinase SYN_01213 65 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 85860361 Common - formate/nitrite transporter family protein SYN_01200 91 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 85860081 Nonpathogen - hypothetical membrane protein SYN_01556 1 COG3149 PulM, Type II secretory pathway, component PulM Intracellular trafficking and secretion 85859921 Common - methyltransferase SYN_00667 123 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 85860291 Nonpathogen - hypothetical cytosolic protein SYN_01214 22 COG2403 COG2403, Predicted GTPase General function prediction only 85858823 Nonpathogen - bacterial regulatory protein, LuxR family SYN_01476 12 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 85860678 Nonpathogen - hypothetical protein SYN_00237 9 None None None 85859196 Common - flagellar basal-body rod protein SYN_02819 125 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 85860348 Common - tetratricopeptide repeat protein SYN_00855 38 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 85860349 Common - export ABC transporter permease protein SYN_00854 175 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 85860204 Nonpathogen - hypothetical cytosolic protein SYN_00594 1 None None None 85857968 Common - Ni/Fe hydrogenase beta subunit SYN_02219 31 None None None 85859362 Common - aminotransferase SYN_01966 230 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 85859641 Common - methionyl-tRNA synthetase SYN_00558 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 85859425 Common - glutamate N-acetyltransferase / amino-acid acetyltransferase SYN_01035 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 85858902 Nonpathogen - hypothetical cytosolic protein SYN_02115 1 None None None 85860379 Common - nifU -like protein involved in Fe-S cluster formation with 2Fe-2S domain SYN_01182 137 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 85858986 Common - hypothetical cytosolic protein SYN_01013 174 COG0759 COG0759, Uncharacterized conserved protein Function unknown 85858961 Common - signal transduction histidine kinase with reciever domain protein SYN_00568 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 85860088 Common - tetraacyldisaccharide 4'-kinase SYN_01563 130 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 85858874 Nonpathogen - hypothetical cytosolic protein SYN_01316 1 None None None 85860983 Common - membrane carboxypeptidase SYN_02082 15 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 85859916 Nonpathogen - hypothetical cytosolic protein SYN_03669 1 None None None 85858849 Common - ankyrin repeat protein SYN_02927 111 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 85860799 Common - zn-dependent hydrolases, including glyoxylases SYN_00318 196 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 85861012 Common - methyltransferase SYN_02054 203 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 85860386 Common - hypothetical cytosolic protein SYN_01175 99 COG1720 COG1720, Uncharacterized conserved protein Function unknown 85860407 Common - permease SYN_00082 43 COG0730 COG0730, Predicted permeases General function prediction only 85858170 Common rpsM 30S ribosomal protein S13 SYN_01598 245 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 85858392 Common - mu-like prophage Flumu I protein SYN_02300 21 COG4388 COG4388, Mu-like prophage I protein General function prediction only 85859782 Common - glycogen phosphorylase SYN_02880 143 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 85859854 Nonpathogen - hypothetical cytosolic protein SYN_00470 1 None None None 85859547 Common - hypothetical membrane protein SYN_01891 3 None None None 85860316 Common - pyruvate formate-lyase activating enzyme SYN_01240 91 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 85860263 Common - membrane-bound lytic murein transglycosylase A SYN_02504 93 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 85859395 Common - phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase SYN_02177 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 85857920 Common - hypothetical membrane protein SYN_00165 14 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 85860577 Nonpathogen - hypothetical cytosolic protein SYN_02465 6 None None None 85860277 Nonpathogen - hypothetical cytosolic protein SYN_02517 1 None None None 85859737 Common - sigma-54-dependent transcriptional activator SYN_01921 161 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 85860012 Common - ABC transporter permease protein SYN_00746 203 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 85860823 Common - endopeptidase SYN_01706 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 85859523 Common - sex pilus assembly protein SYN_01865 41 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 85859038 Common - chemotaxis protein that stimulates methylation of MCP proteins SYN_00965 83 COG1871 CheD, Chemotaxis protein; stimulates methylation of MCP proteins Cell motility and secretion / Signal transduction mechanisms 85858819 Common - flagellar assembly protein SYN_01472 54 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 85859023 Common - alanine dehydrogenase SYN_00979 167 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 85860903 Nonpathogen - hypothetical cytosolic protein SYN_01622 1 None None None 85857876 Common - hypothetical cytosolic protein SYN_00009 12 None None None 85859172 Nonpathogen - hypothetical cytosolic protein SYN_02842 1 None None None 85859678 Common - esterase SYN_02998 17 COG0824 FcbC, Predicted thioesterase General function prediction only 85859822 Common - thiamine biosynthesis protein ThiF SYN_00438 194 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 85860163 Common - signal transduction histidine kinase SYN_00776 173 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 85859321 Common hisS histidyl-tRNA synthetase SYN_02534 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 85858912 Common - iscU protein SYN_02125 146 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 85858882 Common - phosphate/sulphate permease SYN_00387 166 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 85858128 Common - cysteinyl-tRNA synthetase SYN_00075 244 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 85860759 Common - alkaline phosphatase like protein SYN_00362 71 COG0398 COG0398, Uncharacterized conserved protein Function unknown 85861007 Common - hypothetical cytosolic protein SYN_02059 35 COG2006 COG2006, Uncharacterized conserved protein Function unknown 85859115 Nonpathogen - hypothetical protein SYN_01516 1 None None None 85857979 Common - alpha,alpha-trehalose-phosphate synthase [UDP-forming] / trehalose 6-phosphate phosphatase SYN_00622 99 COG0380 OtsA, Trehalose-6-phosphate synthase Carbohydrate transport and metabolism 85860022 Nonpathogen - hypothetical cytosolic protein SYN_00755 3 None None None 85860648 Common - glycosyltransferase involved in cell wall biogenesis SYN_00867 33 None None None 85858893 Common - ATP binding protein SYN_00397 92 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 85857971 Common - nickel-dependent hydrogenase SYN_02222 108 COG3259 FrhA, Coenzyme F420-reducing hydrogenase, alpha subunit Energy production and conversion 85860236 Nonpathogen - hypothetical protein SYN_03735 1 None None None 85858745 Common - transcriptional regulator containing an HTH domain SYN_02755 60 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 85860908 Nonpathogen - hypothetical protein SYN_01616 2 COG4372 COG4372, Uncharacterized protein conserved in bacteria with the myosin-like domain Function unknown 85859044 Common - chemotaxis protein SYN_00959 79 COG1291 MotA, Flagellar motor component Cell motility and secretion 85858119 Nonpathogen - hypothetical GTP-binding protein SYN_01277 10 None None None 85858491 Common - tetrapyrrole (corrin/porphyrin) methylase family protein SYN_00530 213 COG0313 COG0313, Predicted methyltransferases General function prediction only 85859757 Common - hypothetical cytosolic protein SYN_01420 9 None None None 85860369 Nonpathogen - hypothetical cytosolic protein SYN_01192 1 None None None 85860393 Nonpathogen - Fe-S oxidoreductase SYN_01168 10 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 85858191 Nonpathogen - hypothetical cytosolic protein SYN_03322 1 None None None 85859130 Common - tetratricopeptide repeat family protein SYN_01501 156 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 85859975 Common - hypothetical membrane protein SYN_00712 40 COG3647 COG3647, Predicted membrane protein Function unknown 85860243 Nonpathogen - hypothetical cytosolic protein SYN_03014 1 None None None 85860472 Common - methyltransferase SYN_02653 39 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 85860037 Common - hypothetical cytosolic protein SYN_00048 5 None None None 85859961 Nonpathogen - hypothetical cytosolic protein SYN_00700 1 None None None 85859141 Nonpathogen - flp pilus assembly protein, protease SYN_01490 7 COG4960 CpaA, Flp pilus assembly protein, protease CpaA Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 85858444 Nonpathogen - hypothetical cytosolic protein SYN_02246 6 COG4006 COG4006, Uncharacterized protein conserved in archaea Function unknown 85859146 Common - ABC transporter ATP-binding protein SYN_03206 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 85860090 Common - lipid-A-disaccharide synthase SYN_01565 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 85859980 Common - NTP pyrophosphohydrolase containing a Zn-finger N SYN_00716 117 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 85859795 Nonpathogen - hypothetical cytosolic protein SYN_02893 1 None None None 85858459 Common - fructose-1,6-bisphosphatase SYN_02232 37 COG1980 COG1980, Archaeal fructose 1,6-bisphosphatase Carbohydrate transport and metabolism 85860615 Common - iron(III) dicitrate transport ATP-binding protein SYN_01054 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 85859512 Common - helicase SYN_01854 124 COG1204 COG1204, Superfamily II helicase General function prediction only 85858557 Nonpathogen - hypothetical cytosolic protein SYN_01357 4 None None None 85858538 Common - protein-glutamate methylesterase SYN_00430 221 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 85858388 Common - mu-like prophage Flumu protein gp28 SYN_02304 31 COG4373 COG4373, Mu-like prophage FluMu protein gp28 General function prediction only 85858198 Common - dedA family protein SYN_00515 153 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 85858398 Common - hypothetical cytosolic protein SYN_02294 4 None None None 85860185 Common - type 4 prepilin-like proteins leader peptide processing enzyme SYN_00575 129 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 85859464 Nonpathogen - hypothetical cytosolic protein SYN_03146 1 None None None 85858898 Nonpathogen - hypothetical protein SYN_02111 3 None None None 85859666 Common - n-(5'-phosphoribosyl)anthranilate isomerase SYN_01943 199 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 85860967 Common - F0F1 ATP synthase subunit epsilon SYN_02098 51 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 85858909 Common - threonine synthase SYN_02122 145 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 85860072 Common - general secretion pathway protein D SYN_01548 142 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 85860092 Common - acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase SYN_01567 160 COG1043 LpxA, Acyl- acyl carrier protein 85859493 Common - alpA-like transcriptional regulator SYN_01834 20 COG3311 AlpA, Predicted transcriptional regulator Transcription 85860074 Common - general secretion pathway protein F SYN_01550 147 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 85858026 Common - 6,7-dimethyl-8-ribityllumazine synthase SYN_02372 230 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 85858041 Common - outer membrane OmpA family protein SYN_02561 173 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 85858728 Common - uncharacterized protein with SCP/PR1 domain SYN_00196 48 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 85860372 Nonpathogen - hypothetical cytosolic protein SYN_01189 4 COG1433 COG1433, Uncharacterized conserved protein Function unknown 85860229 Nonpathogen - hypothetical cytosolic protein SYN_01589 1 None None None 85859901 Common - acetyl-CoA synthetase SYN_00647 144 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 85858975 Common - SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase SYN_01023 199 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 85860553 Common thiE thiamine-phosphate pyrophosphorylase SYN_00302 207 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 85858104 Common - ABC-type transport system involved in resistance to organic solvents, ATPase component SYN_01263 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 85858450 Nonpathogen - hypothetical cytosolic protein SYN_03395 1 None None None 85858221 Nonpathogen - acyl carrier protein SYN_01151 10 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 85859106 Common - oligopeptide transport system permease protein SYN_01342 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 85858910 Nonpathogen - hypothetical cytosolic protein SYN_02124 1 None None None 85859657 Common - chorismate synthase SYN_01934 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 85859784 Nonpathogen - hypothetical cytosolic protein SYN_02882 1 None None None 85858743 Common - ATP-dependent protease La SYN_02756 30 COG4930 COG4930, Predicted ATP-dependent Lon-type protease Posttranslational modification, protein turnover, chaperones 85858440 Nonpathogen - hypothetical cytosolic protein SYN_02250 4 COG1769 COG1769, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 85860701 Common - Fe-S oxidoreductase SYN_02421 156 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 85858040 Nonpathogen - hypothetical membrane protein SYN_02560 1 None None None 85859095 Common - hypothetical cytosolic protein SYN_03199 205 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 85858792 Nonpathogen - hypothetical membrane protein SYN_02712 1 None None None 85860957 Common - hypothetical protein SYN_03849 15 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 85858652 Common - transcriptional regulator with sigma 54 interaction domain SYN_02899 172 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 85858007 Common - ABC-type tungstate transport permease protein SYN_00838 193 COG4662 TupA, ABC-type tungstate transport system, periplasmic component Coenzyme metabolism 85859718 Nonpathogen - hypothetical protein SYN_03004 3 None None None 85860839 Common - hypothetical membrane protein SYN_01688 23 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 85858228 Common - glycosyltransferase SYN_01144 111 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 85859352 Nonpathogen - hypothetical membrane protein SYN_03060 5 None None None 85858266 Common - glycosyltransferase SYN_01107 207 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 85858883 Common - hypothetical membrane protein SYN_00388 74 COG2928 COG2928, Uncharacterized conserved protein Function unknown 85860005 Nonpathogen - hypothetical membrane protein SYN_00739 1 None None None 85858082 Nonpathogen - hypothetical membrane protein SYN_01433 1 None None None 85860748 Nonpathogen - hypothetical cytosolic protein SYN_00373 5 None None None 85858047 Common - 3-oxoacyl-[acyl-carrier-protein] synthase SYN_02566 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 85860723 Common - 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase SYN_02399 203 COG1165 MenD, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase Coenzyme metabolism 85858840 Nonpathogen - transposase SYN_00403 1 None None None 85859278 Common - dihydrodipicolinate synthase SYN_02161 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 85859378 Common - soluble lytic murein transglycosylase SYN_02783 136 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 85859559 Common - mannosyltransferase SYN_01902 106 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 85860478 Common - glucose-1-phosphate thymidylyltransferase SYN_02647 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 85858412 Common - rdd family protein SYN_02280 48 COG1714 COG1714, Predicted membrane protein/domain Function unknown 85858861 Nonpathogen - hypothetical cytosolic protein SYN_01330 1 None None None 85859942 Common - methylmalonyl CoA epimerase SYN_00683 73 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 85860271 Common - coproporphyrinogen oxidase (NAD) SYN_02511 42 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 85858564 Common - aromatic ring hydroxylase SYN_02445 50 COG2368 COG2368, Aromatic ring hydroxylase Secondary metabolites biosynthesis, transport, and catabolism 85858583 Common - transposase SYN_02975 29 None None None 85858149 Common rplB 50S ribosomal protein L2 SYN_00988 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 85859412 Common - hypothetical cytosolic protein SYN_02934 69 COG0622 COG0622, Predicted phosphoesterase General function prediction only 85858323 Nonpathogen - hypothetical cytosolic protein SYN_03033 2 COG3001 COG3001, Uncharacterized protein conserved in bacteria Function unknown 85858635 Common - endonuclease V SYN_01952 73 COG1515 Nfi, Deoxyinosine 3'endonuclease (endonuclease V) DNA replication, recombination, and repair 85860352 Common - type I secretion outer membrane protein SYN_00851 111 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 85857931 Common - pyruvate:ferredoxin oxidoreductase beta subunit SYN_00154 80 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 85858740 Common - transcription-repair coupling factor SYN_02759 233 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 85860870 Common - 6-hydroxycyclohex-1-ene-1-carboxyl-CoA dehydrogenase SYN_01655 205 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 85859933 Nonpathogen - hypothetical cytosolic protein SYN_03678 1 None None None 85860691 Common - cold shock protein SYN_02432 181 COG1278 CspC, Cold shock proteins Transcription 85860960 Common - F0F1-type ATP synthase, gamma subunit SYN_02105 191 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 85859001 Nonpathogen - hypothetical cytosolic protein SYN_03188 1 None None None 85860813 Common - multimodular transpeptidase-transglycosylase SYN_00304 205 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 85859433 Common - ribosome recycling factor SYN_00919 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 85859877 Nonpathogen - hypothetical cytosolic protein SYN_03088 1 None None None 85858259 Nonpathogen - nucleotidyltransferase SYN_01114 13 COG1708 COG1708, Predicted nucleotidyltransferases General function prediction only 85859059 Common - ribosome-associated factor Y SYN_00944 151 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 85858474 Common - ATP synthase delta chain SYN_00547 176 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 85860862 Common - electron transport complex protein, NADH-binding subunit SYN_01664 102 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 85860815 Common - acetolactate synthase large subunit SYN_01713 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 85860060 Common glyQ glycyl-tRNA synthetase subunit alpha SYN_01536 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 85858701 Common - glycosyltransferase SYN_00130 211 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 85860307 Common - flavodoxin SYN_01229 44 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 85857864 Common - transcriptional regulator, GntR family SYN_03226 49 COG1802 GntR, Transcriptional regulators Transcription 161347551 Common argC N-acetyl-gamma-glutamyl-phosphate reductase SYN_00234 216 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 85860887 Common - 2,3-dihydroxybenzoate-AMP ligase SYN_01638 223 COG1021 EntE, Peptide arylation enzymes Secondary metabolites biosynthesis, transport, and catabolism 85858107 Common - surface lipoprotein SYN_01266 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 85860879 Nonpathogen - methyl-viologen-reducing hydrogenase, delta subunit SYN_01646 28 COG1908 FrhD, Coenzyme F420-reducing hydrogenase, delta subunit Energy production and conversion 85860782 Common - glutaredoxin-like protein SYN_00338 67 None None None 85860067 Nonpathogen - hypothetical cytosolic protein SYN_01542 1 None None None 85858939 Nonpathogen - hypothetical cytosolic protein SYN_01371 1 None None None 85860194 Common - GDP-mannose 4,6 dehydratase SYN_00584 185 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 85860218 Common - ATP-binding protein SYN_00610 249 COG1119 ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA Inorganic ion transport and metabolism 85860539 Common - signal transduction histidine kinase SYN_01808 222 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 85860556 Nonpathogen - hypothetical membrane protein SYN_00299 1 None None None 85859629 Common - exodeoxyribonuclease VII small subunit SYN_02458 135 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 85858122 Common - RNA polymerase subunit SYN_01280 101 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 85858161 Common - SSU ribosomal protein S8P SYN_03316 235 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 85858730 Common - outer membrane porin protein SYN_00198 165 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 85860225 Nonpathogen - hypothetical cytosolic protein SYN_03020 1 None None None 85859453 Common - D-tyrosyl-tRNA deacylase SYN_00899 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 85860930 Nonpathogen - hypothetical cytosolic protein SYN_03839 1 None None None 85859357 Nonpathogen - putative peptidoglycan binding protein SYN_01961 9 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 85859229 Nonpathogen - hypothetical cytosolic protein SYN_01384 1 None None None 85857996 Common - molybdenum cofactor biosynthesis protein A SYN_01960 200 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 85858464 Common - DNA -damage-inducible protein J SYN_02228 26 COG3077 RelB, DNA-damage-inducible protein J DNA replication, recombination, and repair 85858533 Common - chemotaxis protein SYN_00435 115 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 85858374 Nonpathogen - hypothetical cytosolic protein SYN_03373 1 None None None 85858401 Common - phage protein SYN_02291 3 None None None 85859974 Common - hypothetical protein SYN_00711 25 None None None 85860439 Common - undecaprenyl-phosphate galactosephosphotransferase SYN_02686 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 85858391 Common - mu-like prophage Flumu G protein SYN_02301 25 COG5005 COG5005, Mu-like prophage protein gpG General function prediction only 85860989 Nonpathogen - hypothetical cytosolic protein SYN_02077 1 None None None 85859008 Common - transposase SYN_00117 63 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 85858012 Nonpathogen - hypothetical cytosolic protein SYN_03243 16 COG1693 COG1693, Uncharacterized protein conserved in archaea Function unknown 85859249 Common - radical SAM superfamily protein SYN_00275 53 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 85860484 Common - cofactor-independent phosphoglycerate mutase SYN_02641 51 COG3635 COG3635, Predicted phosphoglycerate mutase, AP superfamily Carbohydrate transport and metabolism 85858246 Common - hypothetical protein SYN_01126 10 COG3204 COG3204, Uncharacterized protein conserved in bacteria Function unknown 85859744 Common - hypothetical membrane protein SYN_01406 74 COG1950 COG1950, Predicted membrane protein Function unknown 85858346 Common - dienelactone hydrolase family protein SYN_02346 111 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 85860027 Common - hit family hydrolase SYN_00760 230 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 85859402 Common - erfK/srfK family protein SYN_02184 89 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 85860200 Common - two-component system response regulator SYN_00590 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 85859570 Common - predicted transcriptional regulator SYN_01914 9 COG5340 COG5340, Predicted transcriptional regulator Transcription 85858629 Common - relA / spoT related protein SYN_01575 22 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 85859772 Common - methylenetetrahydrofolate reductase SYN_02872 73 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 85859696 Common - chlorohydrolase/deaminase family protein SYN_01991 172 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 85859706 Common - phosphoheptose isomerase SYN_01980 122 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 85858614 Common - hypothetical membrane protein SYN_02943 123 COG0628 PerM, Predicted permease General function prediction only 85860145 Nonpathogen - hypothetical cytosolic protein SYN_00793 1 None None None 85858618 Nonpathogen - hypothetical cytosolic protein SYN_02939 4 None None None 85859989 Common - chaperone protein SYN_00725 177 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 85859686 Common - glutamine amidotransferases class-II SYN_01087 43 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 85857938 Nonpathogen - hypothetical cytosolic protein SYN_00147 9 COG3303 NrfA, Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit Inorganic ion transport and metabolism 85859577 Common - hypothetical cytosolic protein SYN_02193 27 None None None 85859419 Common - pyruvate carboxylase carboxyltransferase subunit SYN_01040 182 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 85859723 Common - LSU ribosomal protein L9P SYN_00641 216 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 85860719 Common - outer membrane protein SYN_02403 141 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 85858088 Common - thioredoxin reductase SYN_01439 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 85860945 Common - phosphate transport regulator SYN_00205 78 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 85860442 Common - UDP-N-acetylglucosamine 2-epimerase SYN_02683 154 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 85860765 Common - hypothetical membrane protein SYN_00356 9 None None None 85860412 Nonpathogen - hypothetical cytosolic protein SYN_00087 1 None None None 85860323 Common - quaternary ammonium compound-resistance protein SYN_01248 146 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 85858625 Nonpathogen - hypothetical protein SYN_00202 8 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 85858283 Common - indole-3-glycerol phosphate synthase SYN_02591 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 85859519 Common - hypothetical sex pilus assembly and synthesis protein SYN_01861 19 None None None 85858695 Common - transposase SYN_03159 87 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 85859620 Common - rare lipoprotein A SYN_01997 71 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 85859169 Common - phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB SYN_02845 39 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 85860249 Nonpathogen - hypothetical cytosolic protein SYN_03011 1 None None None 85860032 Common - ATP phosphoribosyltransferase SYN_03109 203 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 85858268 Nonpathogen - hypothetical membrane protein SYN_01105 2 COG5434 PGU1, Endopygalactorunase Cell envelope biogenesis, outer membrane 85858550 Common - nuclease subunit of the excinuclease complex SYN_01348 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 85860514 Common - polynucleotide phosphorylase/polyadenylase SYN_01780 239 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 85859483 Common - hypothetical cytosolic protein SYN_01823 22 None None None 85859827 Common - hypothetical membrane protein SYN_00443 58 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 85860430 Common - periplasmic protein involved in polysaccharide export SYN_02695 109 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 85859552 Nonpathogen - hypothetical cytosolic protein SYN_01894 1 None None None 85858577 Common - calcineurin-like phosphoesterase SYN_02978 81 COG1692 COG1692, Uncharacterized protein conserved in bacteria Function unknown 85858061 Common - signal transduction histidine kinase SYN_02581 201 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 85858675 Common - glucosamine--fructose-6-phosphate aminotransferase (isomerizing) SYN_02923 233 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 85860732 Common - transposase SYN_02390 5 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 85859442 Common - adenine-specific methyltransferase SYN_00910 212 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 85858672 Common - NADPH-dependent FMN reductase SYN_02920 45 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 85857871 Common - GTPase dynamin-related SYN_00005 19 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 85860509 Common - pili assembly protein SYN_01775 43 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 161347549 Common obgE GTPase ObgE SYN_01351 249 COG0536 Obg, Predicted GTPase General function prediction only 85859216 Common - tRNA (uracil-5-)-methyltransferase Gid SYN_02799 189 COG1206 Gid, NAD(FAD)-utilizing enzyme possibly involved in translation Translation, ribosomal structure and biogenesis 85860756 Common - ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components SYN_00365 32 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 85858355 Common - PAS domain protein SYN_03037 60 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 85859250 Common - fatty acid binding protein SYN_00274 54 COG1944 COG1944, Uncharacterized conserved protein Function unknown 85859461 Common - thioesterase SYN_00892 136 COG0824 FcbC, Predicted thioesterase General function prediction only 85859408 Common - aspartate aminotransferase SYN_02937 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 85858356 Nonpathogen - hypothetical cytosolic protein SYN_02335 1 None None None 85860849 Nonpathogen - hypothetical cytosolic protein SYN_01679 1 None None None 85858643 Common - isochorismate hydrolase SYN_01752 31 COG1535 EntB, Isochorismate hydrolase Secondary metabolites biosynthesis, transport, and catabolism 85860588 Common - hypothetical cytosolic protein SYN_02477 15 None None None 85858425 Common - radical SAM superfamily protein SYN_02266 193 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 85860517 Common - tRNA pseudouridine synthase B SYN_01783 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 85860633 Common - hypothetical cytosolic protein SYN_01072 25 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 85860057 Common - dihydroorotase SYN_01533 212 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 85859770 Common - histone deacetylase domain protein SYN_02870 161 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 85858989 Common - type I secretion outer membrane protein SYN_01010 128 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 85858288 Common - propionate CoA-transferase SYN_02597 100 COG4670 COG4670, Acyl CoA:acetate/3-ketoacid CoA transferase Lipid metabolism 85858081 Nonpathogen - hypothetical cytosolic protein SYN_01432 1 None None None