Pseudoalteromonas haloplanktis TAC125 chromosome I, complete sequence NC_007481 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 77361829 Common - protein with ubiquinone carrier domain, SCP-like PSHAa2927 31 COG3165 COG3165, Uncharacterized protein conserved in bacteria Function unknown 77361354 Common - RNA polymerase sigma factor PSHAa2438 173 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 77359335 Common secB preprotein translocase subunit SecB PSHAa0369 108 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 77359305 Common - hypothetical protein PSHAa0338 211 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 77359804 Common - hypothetical protein PSHAa0855 42 COG3530 COG3530, Uncharacterized protein conserved in bacteria Function unknown 77361049 Nonpathogen - hypothetical protein PSHAa2126 2 None None None 77360872 Common - hypothetical protein PSHAa1940 44 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 77361210 Common argHA bifunctional argininosuccinate lyase/N-acetylglutamate synthase PSHAa2287 227 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 77359222 Common - hypothetical protein PSHAa0251 6 None None None 77359894 Common - hypothetical protein PSHAa0948 198 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 77361386 Common - hypothetical protein PSHAa2471 51 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 77360425 Common - hypothetical protein PSHAa1482 60 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 77361559 Common dfp bifunctional: 4'-phosphopantothenoylcysteine decarboxylase (N); phosphopantothenoylcysteine synthetase (C), FMN-binding PSHAa2644 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 77360638 Common - hypothetical protein PSHAa1697 30 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 77359890 Common rpsP 30S ribosomal protein S16 PSHAa0944 211 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 77360902 Common - hypothetical protein PSHAa1978 13 COG5595 COG5595, Zn-ribbon-containing, possibly nucleic-acid-binding protein General function prediction only 77359079 Common add adenosine deaminase PSHAa0102 107 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 77360735 Common - hypothetical protein PSHAa1795 156 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 77361798 Common fabR DNA-binding transcriptional repressor FabR PSHAa2896 50 COG1309 AcrR, Transcriptional regulator Transcription 77360413 Common metE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase PSHAa1470 146 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 77359450 Common psd phosphatidylserine decarboxylase PSHAa0486 97 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 77360359 Common - ferredoxin PSHAa1416 50 COG0633 Fdx, Ferredoxin Energy production and conversion 77361812 Common - periplasmic dipeptidase PSHAa2910 103 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 77359404 Common - phytase domain protein PSHAa0438 19 COG4247 Phy, 3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase) Lipid metabolism 77361396 Common - enoyl-CoA hydratase PSHAa2481 141 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 77360416 Common - hypothetical protein PSHAa1473 3 None None None 77360456 Nonpathogen - hypothetical protein PSHAa1515 1 None None None 77360650 Nonpathogen - hypothetical protein PSHAa1709 1 None None None 77361696 Common dgkA diacylglycerol kinase PSHAa2786 69 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 162139921 Common sthA soluble pyridine nucleotide transhydrogenase PSHAa2898 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 77360409 Common - hypothetical protein PSHAa1466 4 None None None 77361573 Common mdh malate dehydrogenase PSHAa2658 202 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 77360876 Common - hypothetical protein PSHAa1944 10 None None None 77360710 Common galT galactose-1-phosphate uridylyltransferase PSHAa1770 79 COG1085 GalT, Galactose-1-phosphate uridylyltransferase Energy production and conversion 77359243 Common motX polar flagellar protein PSHAa0276 14 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 77361163 Common nqrB Na(+)-translocating NADH-quinone reductase subunit B PSHAa2240 76 COG1805 NqrB, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB Energy production and conversion 77359468 Common srmB ATP-dependent RNA helicase SrmB PSHAa0510 240 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 77359773 Common ccmC heme exporter protein C (Cytochrome c-type biogenesis protein ccmC) PSHAa0824 109 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 77361735 Common - hypothetical protein PSHAa2831 8 None None None 77361036 Common - hypothetical protein PSHAa2113 37 COG1315 COG1315, Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain DNA replication, recombination, and repair 77360545 Common - hypothetical protein PSHAa1604 33 COG3439 COG3439, Uncharacterized conserved protein Function unknown 77360059 Common - regulator protein PSHAa1116 177 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 77359194 Common rpoC DNA-directed RNA polymerase subunit beta' PSHAa0223 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 77361219 Common - ABC-type transport system, permease component PSHAa2296 174 COG1511 COG1511, Predicted membrane protein Function unknown 77360220 Common - hypothetical protein PSHAa1277 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 77360180 Common - transporter protein PSHAa1237 47 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 77361227 Common gcp Gcp glycoprotease homolog PSHAa2304 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 77361066 Common mhpE 4-hydroxy-2-ketovalerate aldolase PSHAa2143 209 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 77359167 Common astD succinylglutamic semialdehyde dehydrogenase PSHAa0196 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77360599 Common kdsB CTP:CMP-3-deoxy-D-manno-octulosonate transferase PSHAa1658 137 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 77361053 Common - acyl-CoA dehydrogenase protein PSHAa2130 147 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77359737 Common tag 3-methyl-adenine DNA glycosylase I PSHAa0788 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 77360866 Nonpathogen - hypothetical protein PSHAa1934 2 None None None 77359915 Common - elongation factor P PSHAa0969 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 77359058 Common - hydrolase PSHAa0081 185 COG0388 COG0388, Predicted amidohydrolase General function prediction only 162139928 Common flhA flagellar biosynthesis protein A PSHAa0806 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 77359027 Common - methylase PSHAa0049 49 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 77361556 Common rpmG 50S ribosomal subunit protein L33 PSHAa2641 136 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 77359679 Common rseB anti sigma E (sigma 24) factor, negative regulator PSHAa0728 48 COG3026 RseB, Negative regulator of sigma E activity Signal transduction mechanisms 77360434 Common fabA 3-hydroxydecanoyl-(acyl carrier protein) dehydratase PSHAa1491 81 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 77360493 Nonpathogen - hypothetical protein PSHAa1552 1 None None None 77360909 Common yejH ATP-dependent helicase with nucleoside triP hydrolase domain PSHAa1985 135 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 77361715 Common rplO 50S ribosomal subunit protein L15 PSHAa2811 199 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 77360895 Common truC tRNA pseudouridine synthase C PSHAa1970 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 77361424 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate 2, 6-diaminopimelate ligase PSHAa2509 211 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 77361779 Nonpathogen - hypothetical protein PSHAa2876 3 None None None 77361784 Common - integral inner membrane permease PSHAa2881 57 COG3213 NnrS, Uncharacterized protein involved in response to NO Inorganic ion transport and metabolism 77360194 Common - hypothetical protein PSHAa1251 12 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 77360564 Common proS prolyl-tRNA synthetase PSHAa1623 247 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 77361196 Common - acrB/acrD/acrF acriflavin resistance protein PSHAa2273 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 77360216 Common - Prolyl endopeptidase PSHAa1273 121 COG1505 COG1505, Serine proteases of the peptidase family S9A Amino acid transport and metabolism 77361561 Common - hypothetical protein PSHAa2646 96 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 77359263 Nonpathogen - hypothetical protein PSHAa0296 1 None None None 77360443 Common - response regulator receiver in two-component signal transduction system PSHAa1501 182 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77360422 Common - hypothetical protein PSHAa1479 2 None None None 77360210 Common - hypothetical protein PSHAa1267 7 None None None 77359157 Common csd cysteine desulfurase PSHAa0186 238 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 77361655 Common hutH histidine ammonia-lyase PSHAa2740 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 77360603 Common - DNA internalization-related competence protein ComEC/Rec2 with Metallo-beta-lactamase superfamily domain PSHAa1662 182 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 77359941 Common - conserved protein of unknown function (yhbC) PSHAa0995 171 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 77360321 Common - hypothetical protein PSHAa1378 98 COG0456 RimI, Acetyltransferases General function prediction only 77359948 Common nlpI lipoprotein NlpI PSHAa1002 68 COG4785 NlpI, Lipoprotein NlpI, contains TPR repeats General function prediction only 77360109 Common fumB fumarate hydratase, class I PSHAa1166 148 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 77360141 Common - hypothetical protein PSHAa1198 15 COG3219 COG3219, Uncharacterized protein conserved in bacteria Function unknown 77361332 Common - hydrolase PSHAa2416 171 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 77360026 Common ligA NAD-dependent DNA ligase PSHAa1083 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 77359954 Common - putative monovalent cation/H+ antiporter subunit F PSHAa1008 81 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 77361846 Common bdhA 3-hydroxybutyrate dehydrogenase PSHAa2944 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 162139931 Common nudE ADP-ribose diphosphatase NudE PSHAa0127 134 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 77361543 Common - hypothetical protein PSHAa2628 4 None None None 77361247 Common - phosphoheptose isomerase PSHAa2324 121 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 77359484 Common - phosphotyrosine protein phosphatase PSHAa0527 136 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 77359366 Common - aminotransferase PSHAa0400 194 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 77360931 Nonpathogen - hypothetical protein PSHAa2007 1 None None None 77360073 Common - membrane protein with ankyrin repeat PSHAa1130 7 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 77361594 Common - conserved protein of unknown function with Maf/Ham1 domain PSHAa2679 198 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 77361770 Common - transmembrane cytochrome oxidase associated protein PSHAa2867 5 None None None 77360684 Common - 4-hydroxy-2-oxoglutarate aldolase / 2-dehydro-3-deoxyphosphogluconate aldolase PSHAa1744 125 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 77360123 Common - enzyme PSHAa1180 58 COG1434 COG1434, Uncharacterized conserved protein Function unknown 77360523 Nonpathogen - hypothetical protein PSHAa1582 1 None None None 77361919 Common - hypothetical protein PSHAa3023 186 COG0759 COG0759, Uncharacterized conserved protein Function unknown 77361865 Common - hypothetical protein PSHAa2963 15 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 77359272 Common cusA cation efflux system protein PSHAa0305 177 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 77359560 Common dksAA RNA polymerase factor PSHAa0606 137 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 77359343 Common - hypothetical protein PSHAa0377 57 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 77359002 Common trkA potassium transporter peripheral membrane component PSHAa0020 145 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 77360816 Common - hypothetical protein PSHAa1878 87 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 77359670 Common - hypothetical protein PSHAa0719 30 COG3137 COG3137, Putative salt-induced outer membrane protein Cell envelope biogenesis, outer membrane 77361144 Nonpathogen - hypothetical protein PSHAa2221 2 None None None 77359232 Common accB acetyl-CoA carboxylase biotin carboxyl carrier protein PSHAa0265 180 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 77360767 Common - hypothetical protein PSHAa1827 4 None None None 77361322 Common - hypothetical protein PSHAa2406 29 COG3619 COG3619, Predicted membrane protein Function unknown 77361082 Common - protease BcsE PSHAa2159 16 None None None 77359595 Common - hypothetical protein PSHAa0642 6 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 77359703 Nonpathogen - hypothetical protein PSHAa0752 1 None None None 77359128 Common cysH phosphoadenosine phosphosulfate reductase PSHAa0156 158 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 77361450 Common - hypothetical protein PSHAa2535 16 COG3105 COG3105, Uncharacterized protein conserved in bacteria Function unknown 77360885 Common - peptidase PSHAa1953 143 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 77360538 Nonpathogen - hypothetical protein PSHAa1597 1 None None None 77359507 Common arcA DNA-binding response regulator in two-component regulatory system with ArcB or CpxA PSHAa0551 217 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77361517 Common pilU twitching motility protein PilU (type IV pili) PSHAa2602 188 COG5008 PilU, Tfp pilus assembly protein, ATPase PilU Cell motility and secretion / Intracellular trafficking and secretion 77360478 Common - hypothetical protein PSHAa1537 6 COG1709 COG1709, Predicted transcriptional regulator Transcription 77360574 Common - succinylglutamate desuccinylase PSHAa1633 24 COG2988 COG2988, Succinylglutamate desuccinylase Amino acid transport and metabolism 77361598 Common - hypothetical protein PSHAa2683 105 COG1262 COG1262, Uncharacterized conserved protein Function unknown 77359757 Common flhG flagellar biosynthetic protein FlhG PSHAa0808 167 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 77360371 Common - hypothetical protein PSHAa1428 60 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 77361644 Common - conserved protein of unknown function, cell division protein PSHAa2729 22 COG3087 FtsN, Cell division protein Cell division and chromosome partitioning 77360464 Common - hypothetical protein PSHAa1523 20 None None None 77359692 Common pyrG CTP synthetase PSHAa0741 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 77359717 Common cheR chemotaxis protein methyltransferase PSHAa0767 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 77361681 Common - hypothetical protein PSHAa2766 13 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 77359784 Common - competence protein PSHAa0835 122 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 77361148 Common - putative ABC transporter ATP-binding protein PSHAa2225 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 77360900 Common - hypothetical protein PSHAa1976 23 None None None 77360755 Common rluC 23S rRNA pseudouridylate synthase PSHAa1815 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 77359569 Nonpathogen - hypothetical protein PSHAa0616 1 None None None 77359111 Common - hypothetical protein PSHAa0139 6 COG3096 MukB, Uncharacterized protein involved in chromosome partitioning Cell division and chromosome partitioning 77359629 Common - hypothetical protein PSHAa0677 2 None None None 77359859 Nonpathogen - hypothetical protein ; membrane protein PSHAa0911 1 None None None 77360666 Common cspD nucleic acid-binding domain, cold-shock RNA chaperone PSHAa1726 177 COG1278 CspC, Cold shock proteins Transcription 77359254 Common - mandelate racemase PSHAa0287 106 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 77361012 Nonpathogen - hypothetical protein PSHAa2088 1 None None None 77359080 Common - hypothetical protein PSHAa0103 90 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 77361276 Common - phage integrase PSHAa2360 9 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 77361768 Common - Polyprenyltransferase PSHAa2865 170 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 77360310 Common eda multifunctional: 2-keto-3-deoxygluconate 6-phosphate aldolase; 2-keto-4-hydroxyglutarate aldolase; oxaloacetate decarboxylase PSHAa1367 125 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 77360620 Common proQ putative solute/DNA competence effector PSHAa1679 32 COG3109 ProQ, Activator of osmoprotectant transporter ProP Signal transduction mechanisms 77361791 Nonpathogen - secreted protein PSHAa2888 2 None None None 77359030 Common - sensor protein PSHAa0052 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77359337 Common - tRNA/rRNA methyltransferase PSHAa0371 160 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 77359372 Common - hypothetical protein PSHAa0406 68 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 77361761 Common - hypothetical protein PSHAa2858 148 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 77359699 Common lgt phosphatidylglycerol-prolipoprotein diacylglyceryl transferase PSHAa0748 208 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 77360185 Common - hypothetical protein PSHAa1242 7 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 77361905 Common atpG membrane-bound ATP synthase, F1 sector, gamma-subunit PSHAa3009 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 77361660 Common - Peptidase, M13 (lipoprotein) PSHAa2745 63 COG3590 PepO, Predicted metalloendopeptidase Posttranslational modification, protein turnover, chaperones 77360951 Common skp periplasmic molecular chaperone for outer membrane proteins PSHAa2027 49 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 77360693 Common - hypothetical protein PSHAa1753 141 COG1741 COG1741, Pirin-related protein General function prediction only 77360068 Common - lipoprotein-34 NlpB PSHAa1125 20 COG3317 NlpB, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 77361125 Common osmC osmotically inducible protein C PSHAa2202 74 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 77358993 Common fadB multifunctional fatty acid oxidation complex subunit alpha PSHAa0011 170 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 77360435 Nonpathogen - hypothetical protein PSHAa1492 1 None None None 77361172 Common - DNA binding protein PSHAa2249 19 None None None 77361407 Common - Aminopeptidase PSHAa2492 166 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 77359608 Common prfC peptide chain release factor 3 PSHAa0655 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 77360166 Common bcr efflux pump PSHAa1223 212 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77361605 Common mshB Mannose-sensitive agglutinin (MSHA) biogenesis protein MshB (pilus type IV) PSHAa2690 7 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 77361061 Common - TonB-dependent receptor PSHAa2138 124 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 77359607 Common - sensory transduction histidine kinase PSHAa0654 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77361675 Common - Cytochrome c5 PSHAa2760 46 COG3245 CycB, Cytochrome c5 Energy production and conversion 77359121 Common rplV 50S ribosomal protein L22 PSHAa0149 218 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 77361461 Common ksdD D-arabinose 5-phosphate isomerase PSHAa2546 162 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 77361031 Nonpathogen - hypothetical protein PSHAa2108 2 None None None 77361668 Common engB GTPase EngB PSHAa2753 184 COG0218 COG0218, Predicted GTPase General function prediction only 77361705 Common asnA asparagine synthetase AsnA PSHAa2796 31 COG2502 AsnA, Asparagine synthetase A Amino acid transport and metabolism 77359817 Common yhbY RNA binding protein; ancient RNA-binding IF3-C fold PSHAa0868 96 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 77360552 Nonpathogen - hypothetical protein PSHAa1611 1 None None None 77360913 Common - hypothetical protein PSHAa1989 114 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 77359838 Common - acyl-CoA dehydrogenase protein PSHAa0889 144 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77361338 Common - hypothetical protein PSHAa2422 138 COG0795 COG0795, Predicted permeases General function prediction only 77359710 Common oxyR hydrogen peroxide-inducible genes activator similar to OxyR (but also to other LysR like activators) PSHAa0760 189 COG0583 LysR, Transcriptional regulator Transcription 77361700 Common gmk guanylate kinase PSHAa2790 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 77359992 Common miaB involved in methylthiolation of isopentenylated A37 derivatives in tRNA, Fe-S protein PSHAa1046 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 77361043 Common - transcriptional regulator PSHAa2120 68 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 77359033 Common - pyridoxal phosphate dependent enzyme PSHAa0055 173 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 77361565 Common ahpC Peroxiredoxin, AhpC/Tsa PSHAa2650 82 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 77359666 Common - hypothetical protein PSHAa0715 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 77359742 Common fliG flagellar motor switch protein G PSHAa0793 125 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 77360340 Common infC translation initiation factor IF-3 PSHAa1397 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 77361822 Common cpsB mannose-1-phosphate guanyltransferase, colanic acid synthesis PSHAa2920 164 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 77360806 Common nadA quinolinate synthetase PSHAa1866 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 77360119 Common - hypothetical protein PSHAa1176 6 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 77359831 Common paaF enoyl-CoA hydratase PSHAa0882 179 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 77359039 Common - glutathione peroxidase PSHAa0062 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 77360578 Common - hypothetical protein PSHAa1637 8 None None None 77358986 Common gyrB DNA gyrase subunit B PSHAa0004 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 77360997 Common folC bifunctional: folylpolyglutamate synthase; dihydrofolate synthase PSHAa2073 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 77359212 Common - general secretion pathway protein M PSHAa0241 20 COG3149 PulM, Type II secretory pathway, component PulM Intracellular trafficking and secretion 77360775 Common - Beta-ureidopropionase PSHAa1835 206 COG0388 COG0388, Predicted amidohydrolase General function prediction only 77361087 Common bcsZ endo-1,4-D-glucanase PSHAa2164 31 COG3405 CelA, Endoglucanase Y Carbohydrate transport and metabolism 77361026 Nonpathogen - hypothetical protein PSHAa2102 1 None None None 77359387 Common - phage integrase PSHAa0421 83 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 77361730 Common - substate-binding protein involved in drug resistance PSHAa2826 178 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 77361550 Common ksgA dimethyladenosine transferase PSHAa2635 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 77359474 Common recJ Single-stranded-DNA-specific exonuclease, 5'--> 3'-specific PSHAa0516 192 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 77361305 Common dinB DNA polymerase IV PSHAa2389 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 77360462 Nonpathogen - hypothetical protein PSHAa1521 1 None None None 77359119 Common rplB 50S ribosomal protein L2 PSHAa0147 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 77359304 Nonpathogen - hypothetical protein PSHAa0337 1 None None None 77359377 Common - hypothetical protein PSHAa0411 29 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 77361510 Common glnE adenylyl transferase for glutamine synthetase PSHAa2595 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 77361312 Common - two-component sensor histidine kinase PSHAa2396 222 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 77360975 Common sapA ABC transporter periplasmic peptide-binding protein PSHAa2051 213 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 77361113 Common - ThiJ/PfpI protein PSHAa2190 112 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 77361019 Common - hypothetical protein PSHAa2095 47 COG4227 COG4227, Antirestriction protein DNA replication, recombination, and repair 77359735 Common fliS flagellar biosynthesis protein PSHAa0786 69 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 77360042 Common nth endonuclease III; DNA glycosylase/apyrimidinic (AP) lyase, acts on 5-formyluracil and 5-hydroxymethyluracil PSHAa1099 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 77361350 Common alr alanine racemase 1, PLP-binding, biosynthetic PSHAa2434 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 77361827 Common - hypothetical protein PSHAa2925 142 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 77361848 Common - permease PSHAa2946 35 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 77361372 Common dps stress response DNA-binding protein Dps PSHAa2456 109 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 77361635 Common pilM Type IV pilus biogenesis protein PilM PSHAa2720 101 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 77359430 Common - hypothetical protein PSHAa0465 6 None None None 77359889 Common ffh 4.5S-RNP protein, GTP-binding export factor, part of signal recognition particle with 4.5 RNA PSHAa0942 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 77359977 Common leuS leucyl-tRNA synthetase PSHAa1031 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 77361253 Common purL phosphoribosylformylglycinamidine synthase PSHAa2330 232 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 77359492 Common - hypothetical protein PSHAa0535 6 None None None 77359744 Common fliI flagellum-specific ATP synthase PSHAa0795 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 77361474 Common talB transaldolase B PSHAa2559 184 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 77360476 Nonpathogen - hypothetical protein PSHAa1535 1 None None None 77360260 Common metG methionyl-tRNA synthetase PSHAa1317 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 77359177 Nonpathogen - hypothetical protein PSHAa0206 1 None None None 77359936 Common deaD ATP-dependent RNA helicase, cold shock protein A PSHAa0990 235 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 77361187 Common putA bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase PSHAa2264 220 COG4230 COG4230, Delta 1-pyrroline-5-carboxylate dehydrogenase Energy production and conversion 77359130 Nonpathogen - hypothetical protein PSHAa0158 1 None None None 77359548 Common epd D-erythrose 4-phosphate dehydrogenase PSHAa0594 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 77359943 Common infB translation initiation factor IF-2 PSHAa0997 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 77361748 Common - Acyltransferase protein (Phospholipid/glycerol acyltransferase) PSHAa2845 31 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 77359482 Common - hypothetical protein PSHAa0525 8 None None None 77359415 Common - transmembrane protein PSHAa0450 29 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 77359279 Common phoU transcriptional regulator PhoU PSHAa0312 197 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 77361345 Nonpathogen - hypothetical protein PSHAa2429 1 None None None 77360725 Nonpathogen - hypothetical protein PSHAa1785 7 COG5663 COG5663, Uncharacterized conserved protein Function unknown 77361521 Common - integral membrane resistance protein PSHAa2606 56 COG0762 COG0762, Predicted integral membrane protein Function unknown 77359918 Common - peptidase PSHAa0972 198 COG1025 Ptr, Secreted/periplasmic Zn-dependent peptidases, insulinase-like Posttranslational modification, protein turnover, chaperones 77361368 Common - glycosyl transferase PSHAa2452 44 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 77361670 Common - hypothetical protein PSHAa2755 11 COG2353 COG2353, Uncharacterized conserved protein Function unknown 77361357 Common priB primosomal replication protein N PSHAa2441 28 COG2965 PriB, Primosomal replication protein N DNA replication, recombination, and repair 77360152 Common tpx periplasmic thiol peroxidase PSHAa1209 109 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 77359672 Common slyDA FKBP-type peptidyl prolyl cis-trans isomerase (rotamase) PSHAa0721 123 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 77361331 Common - hypothetical protein PSHAa2415 5 COG3239 DesA, Fatty acid desaturase Lipid metabolism 77361293 Common thrC threonine synthase PSHAa2377 202 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 77359965 Common lipA lipoyl synthase PSHAa1019 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 77361238 Common tdh L-threonine 3-dehydrogenase PSHAa2315 212 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 77360092 Common - hypothetical protein PSHAa1149 7 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 77360386 Common - allophanate hydrolase PSHAa1443 99 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 77359553 Common - phosphate ABC transporter PSHAa0599 112 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 77361447 Common rplM 50S ribosomal protein L13 PSHAa2532 233 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 77359759 Common cheY chemotaxis protein PSHAa0810 221 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77361804 Common - G-protein beta WD-40 repeat PSHAa2902 48 COG2319 COG2319, FOG: WD40 repeat General function prediction only 77359523 Common - hypothetical protein PSHAa0568 3 None None None 77361689 Common mdoB phosphoglycerol transferase PSHAa2774 70 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 77359183 Common cysD sulfate adenylyltransferase subunit 2 PSHAa0212 138 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 77360053 Common uvrB excinuclease ABC subunit B PSHAa1110 227 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 77360084 Common agaI 6-phosphogluconolactonase PSHAa1141 122 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 77360921 Common - hypothetical protein ; membrane protein PSHAa1997 46 None None None 77359122 Common rpsC 30S ribosomal protein S3 PSHAa0150 248 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 77361737 Common - cation efflux system (AcrB/AcrD/AcrF) PSHAa2833 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 77360049 Common - hypothetical protein PSHAa1106 162 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 77361494 Common - transporter protein PSHAa2579 45 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 77360272 Common - hypothetical protein PSHAa1329 44 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 77359645 Common - CinA, C-terminal Domain PSHAa0693 190 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 77359698 Common - hypothetical protein PSHAa0747 75 COG0730 COG0730, Predicted permeases General function prediction only 77360268 Common - hypothetical protein PSHAa1325 41 COG3417 FlgN, Collagen-binding surface adhesin SpaP (antigen I/II family) General function prediction only 77360236 Common trpE anthranilate synthase component I PSHAa1293 221 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 77361455 Common - anti-sigma B factor antagonist PSHAa2540 2 COG3113 COG3113, Predicted NTP binding protein (contains STAS domain) General function prediction only 77361433 Common - sensory box protein PSHAa2518 189 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 77361891 Common - hypothetical protein PSHAa2989 5 COG0486 ThdF, Predicted GTPase General function prediction only 77359453 Nonpathogen - hypothetical protein PSHAa0489 1 None None None 77359064 Common - acetyltransferase PSHAa0087 22 None None None 77360069 Common - hypothetical protein PSHAa1126 20 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 77360653 Common crcB protein crcB homolog PSHAa1713 175 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 77361879 Common - secreted alkaline phosphatase PSHAa2977 86 COG1785 PhoA, Alkaline phosphatase Inorganic ion transport and metabolism 77359394 Common - TonB-dependent receptor PSHAa0428 48 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 77361872 Common - membrane-associated protein PSHAa2970 28 COG3295 COG3295, Uncharacterized protein conserved in bacteria Function unknown 77360283 Common - calcium binding protein PSHAa1340 2 COG5126 FRQ1, Ca2+-binding protein (EF-Hand superfamily) Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only 77361175 Common - Voltage-gated ClC-type chloride channel clcA PSHAa2252 127 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 77361134 Common - hypothetical protein PSHAa2211 33 COG5267 COG5267, Uncharacterized protein conserved in bacteria Function unknown 77361137 Common qacF Quaternary ammonium compound-resistance protein (Quarternary ammonium determinant F) PSHAa2214 136 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 77361420 Common ftsW Cell division protein FtsW PSHAa2505 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 77360480 Nonpathogen - hypothetical protein PSHAa1539 1 None None None 77361265 Common - hypothetical protein PSHAa2349 4 None None None 77359148 Common - hypothetical protein PSHAa0177 31 COG3608 COG3608, Predicted deacylase General function prediction only 77361091 Common melA 4-hydroxyphenylpyruvate dioxygenase (4HPPD) (HPD) (HPPDase) PSHAa2168 75 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 77361752 Common envZ osmolarity sensor protein PSHAa2849 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77360095 Common - hypothetical protein PSHAa1152 145 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 77360715 Common prpB 2-methylisocitrate lyase PSHAa1775 131 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 77360998 Common accD acetylCoA carboxylase, carboxyltranferase subunit beta PSHAa2074 218 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 77359100 Common - carbohydrate phosphatase PSHAa0128 197 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 77361090 Common - esterase PSHAa2167 73 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 77361887 Common - hypothetical protein PSHAa2985 8 None None None 77361722 Common rplE 50S ribosomal protein L5 PSHAa2818 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 77360259 Nonpathogen - hypothetical protein PSHAa1316 2 None None None 77360489 Nonpathogen - hypothetical protein PSHAa1548 1 None None None 77360868 Common - hypothetical protein PSHAa1936 3 None None None 77360617 Common pepN aminopeptidase N PSHAa1676 159 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 77359321 Common ftsE cell division protein PSHAa0355 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 77359048 Common - hypothetical protein PSHAa0071 72 COG1238 COG1238, Predicted membrane protein Function unknown 77361155 Nonpathogen - hypothetical protein PSHAa2232 1 None None None 77360733 Nonpathogen - hypothetical protein PSHAa1793 1 None None None 77360756 Common rne RNase E: endoribonuclease for rRNA processing and mRNA degradation; member of the degradosome; involved in the production of deoxyribonucleotides via the formation of NDPs PSHAa1816 196 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 77360679 Common - regulatory protein, GntR PSHAa1739 118 COG2186 FadR, Transcriptional regulators Transcription 77360225 Common phoQ sensory histidine kinase in two-component regulatory system with PhoP PSHAa1282 202 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77361150 Common cyoE protoheme IX farnesyltransferase PSHAa2227 167 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 77360004 Common - transcriptional regulator with tetratricopeptide repeats (TPR) domain PSHAa1061 23 COG2912 COG2912, Uncharacterized conserved protein Function unknown 77359547 Common - hypothetical protein PSHAa0592 2 None None None 77360525 Common - TonB-dependent receptor for ferrichrome transport PSHAa1584 103 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 77359720 Common flgC flagellar biosynthesis; cell-proximal portion of basal-body rod PSHAa0770 125 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 77360104 Common - hypothetical protein PSHAa1161 7 None None None 77359353 Nonpathogen - hypothetical protein PSHAa0387 1 None None None 77359896 Common pheA chorismate mutase P / prephenate dehydratase PSHAa0950 214 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 77360601 Common lpxK tetraacyldisaccharide 4' kinase (lipid A 4'kinase) PSHAa1660 126 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 77361698 Common rph RNase PH (tRNA nucleotidyltransferase) PSHAa2788 183 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 77359330 Common - carboxyl-terminal protease PSHAa0364 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 77359860 Nonpathogen - hypothetical protein PSHAa0912 1 None None None 77361603 Common mshC Mannose-sensitive agglutinin (MSHA) biogenesis protein MshC (pilus type IV) PSHAa2688 4 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 77361154 Common cyoA Ubiquinol oxidase polypeptide II (Cytochrome o subunit 2) (Oxidase BO(3) subunit 2) (Cytochrome o ubiquinol oxidase subunit 2) (Ubiquinol oxidase chain B) PSHAa2231 109 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 77360062 Common - hypothetical protein PSHAa1119 32 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 77360199 Common - deoxycytidylate deaminase PSHAa1256 48 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 77360306 Common - transcriptional regulator PSHAa1363 127 COG1609 PurR, Transcriptional regulators Transcription 77360402 Common - 3-hydroxyisobutyrate dehydrogenase PSHAa1459 171 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 77361916 Common mioC FMN-binding protein, required for biotin synthase activity; insertion of sulfur into desthiobiotin PSHAa3020 75 COG0369 CysJ, Sulfite reductase, alpha subunit (flavoprotein) Inorganic ion transport and metabolism 77359517 Common pepP proline aminopeptidase P II PSHAa0562 244 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 77359754 Common flhB flagellar biosynthesis protein FlhB PSHAa0805 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 77360207 Common - 3-oxoacyl-[acyl-carrier protein] reductase PSHAa1264 236 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 77361880 Common cspE RNA chaperone, transcription antiterminator, affects expression of rpoS and uspA PSHAa2978 179 COG1278 CspC, Cold shock proteins Transcription 77361580 Common gabD succinate-semialdehyde dehydrogenase I, NADP-dependent PSHAa2665 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77360301 Nonpathogen - hypothetical protein PSHAa1358 1 None None None 77359286 Common tgt queuine tRNA-ribosyltransferase PSHAa0319 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 77361231 Common - transcriptional regulator, LysR PSHAa2308 186 COG0583 LysR, Transcriptional regulator Transcription 77359109 Common - potassium channel protein PSHAa0137 15 None None None 77359235 Common amiB N-acetylmuramoyl-l-alanine amidase II PSHAa0268 175 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 77361615 Common dcyD D-cysteine desulfhydrase, PLP-dependent enzyme PSHAa2700 71 COG2515 Acd, 1-aminocyclopropane-1-carboxylate deaminase Amino acid transport and metabolism 77359769 Common - hypothetical protein PSHAa0820 59 COG2257 COG2257, Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB Function unknown 77360799 Common recC exonuclease V, gamma chain with recB and recD: 5' and 3' nuclease, ATPase, recombinase, helicase PSHAa1859 67 COG1330 RecC, Exonuclease V gamma subunit DNA replication, recombination, and repair 77359380 Common - transposase PSHAa0414 101 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 77359443 Common - heat shock protein PSHAa0478 13 COG3187 HslJ, Heat shock protein Posttranslational modification, protein turnover, chaperones 77359570 Nonpathogen - hypothetical protein PSHAa0617 1 None None None 77359010 Common - double-stranded RNA-binding protein PSHAa0028 240 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 77360585 Common sucD succinyl-CoA synthetase, alpha subunit, NAD(P)-binding PSHAa1644 215 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 77361499 Common plsC 1-acyl-sn-glycerol-3-phosphate acyltransferase PSHAa2584 149 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 77359869 Common algZ alginate biosynthesis protein PSHAa0922 102 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 77360441 Common - conserved protein of unknown function; membrane protein PSHAa1499 37 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 77361866 Common - stress protein PSHAa2964 13 COG3428 COG3428, Predicted membrane protein Function unknown 77361609 Common mshM Mannose-sensitive agglutinin (MSHA) biogenesis protein MshM (pilus type IV) PSHAa2694 70 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 77359728 Common flgK flagellar hook-associated PSHAa0778 124 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 77361504 Common cpdA cyclic 3',5'-adenosine monophosphate phosphodiesterase PSHAa2589 57 COG1409 Icc, Predicted phosphohydrolases General function prediction only 77360879 Common purM phosphoribosylaminoimidazole synthetase (AIR synthetase) PSHAa1947 232 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 77361440 Common ecfH hypothetical protein PSHAa2525 71 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 77360250 Common aceK bifunctional isocitrate dehydrogenase kinase/phosphatase protein PSHAa1307 29 COG4579 COG4579, Isocitrate dehydrogenase kinase/phosphatase Signal transduction mechanisms 77360843 Common hda regulatory factor involved in inactivation of DnaA PSHAa1905 194 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 77359849 Common - Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit PSHAa0901 98 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 77359012 Common - oxygen-binding protein PSHAa0030 65 COG2346 COG2346, Truncated hemoglobins General function prediction only 77359437 Nonpathogen - hypothetical protein PSHAa0472 1 None None None 77361529 Common - potassium channel protein PSHAa2614 69 COG1226 Kch, Kef-type K+ transport systems, predicted NAD-binding component Inorganic ion transport and metabolism 77360856 Common - hypothetical protein PSHAa1924 12 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 77361095 Common - hypothetical protein PSHAa2172 16 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 77360631 Common mnmA tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase PSHAa1690 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 77361070 Common - taurine dioxygenase PSHAa2147 47 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 77359823 Common secG preprotein translocase subunit SecG PSHAa0874 74 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 77361741 Nonpathogen - hypothetical protein PSHAa2837 1 None None None 77361638 Common metB cystathionine gamma-synthase, PLP-dependent PSHAa2723 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 77359730 Common fliC flagellin PSHAa0781 124 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 77360515 Common ybiT transport protein (ABC superfamily, atp_bind) PSHAa1574 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 77360534 Nonpathogen - hypothetical protein PSHAa1593 1 None None None 77361050 Nonpathogen - hypothetical protein PSHAa2127 1 None None None 77361729 Common - hypothetical protein PSHAa2825 4 None None None 77360647 Nonpathogen - hypothetical protein ; membrane protein PSHAa1706 2 None None None 77361204 Common - transcriptional regulator PSHAa2281 46 COG1309 AcrR, Transcriptional regulator Transcription 77359579 Nonpathogen - hypothetical protein PSHAa0626 1 None None None 77361329 Common tyrS tyrosyl-tRNA synthetase PSHAa2413 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 77359315 Common rpoD RNA polymerase sigma factor PSHAa0349 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 77359795 Common - peptidase precursor PSHAa0846 49 COG2234 Iap, Predicted aminopeptidases General function prediction only 77359081 Common fre FMN reductase PSHAa0104 90 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 77360746 Common fabF 3-oxoacyl-[acyl-carrier-protein] synthase II PSHAa1806 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 77359091 Common rhlB ATP-dependent RNA helicase RhlB PSHAa0114 231 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 77359248 Nonpathogen - hypothetical protein PSHAa0281 1 None None None 77361853 Common - hypothetical protein PSHAa2951 52 COG4681 COG4681, Uncharacterized protein conserved in bacteria Function unknown 77359917 Common - hypothetical protein PSHAa0971 187 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 77361426 Common ftsL cell division protein PSHAa2511 21 COG3116 FtsL, Cell division protein Cell division and chromosome partitioning 77361613 Common - Mannose-sensitive agglutinin (MSHA) biogenesis protein MshI (pilus type IV) with frame shift PSHAa2698 8 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 77361349 Common - hypothetical protein PSHAa2433 6 None None None 77360179 Common - transcriptional regulator PSHAa1236 149 COG0583 LysR, Transcriptional regulator Transcription 77360183 Common - hypothetical protein PSHAa1240 136 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 77359654 Common - hypothetical protein ; membrane protein PSHAa0702 6 COG4135 COG4135, ABC-type uncharacterized transport system, permease component General function prediction only 77360880 Common purN phosphoribosylglycinamide formyltransferase 1 PSHAa1948 222 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 77361051 Common - acetyl-CoA acetyltransferase or Thiolase PSHAa2128 181 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 77359505 Common - hypothetical protein PSHAa0549 70 COG1469 COG1469, Uncharacterized conserved protein Function unknown 77361017 Common hsdS type I restriction-modification system, S subunit PSHAa2093 84 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 77361533 Common - hypothetical protein PSHAa2618 17 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 77361868 Common - hypothetical protein PSHAa2966 61 COG0676 COG0676, Uncharacterized enzymes related to aldose 1-epimerase Carbohydrate transport and metabolism 77359476 Common lysS lysyl-tRNA synthetase PSHAa0518 248 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 77359767 Common cheW purine-binding chemotaxis protein PSHAa0818 138 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 77360864 Common - Isopenicillin N synthase PSHAa1932 55 COG3491 PcbC, Isopenicillin N synthase and related dioxygenases General function prediction only 77359169 Common - hypothetical protein PSHAa0198 87 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 77360331 Common lolC transport protein of outer membrane lipoproteins (ABC superfamily, membrane) PSHAa1388 217 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 77359615 Common radA DNA repair protein RadA PSHAa0663 203 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 77359357 Common aceE pyruvate dehydrogenase subunit E1 PSHAa0391 150 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 77361278 Common motB flagellar motor protein MotB PSHAa2362 115 COG1360 MotB, Flagellar motor protein Cell motility and secretion 77360006 Common kdsA 2-dehydro-3-deoxyphosphooctonate aldolase PSHAa1063 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 77361225 Common folB dihydroneopterin aldolase (DHNA) PSHAa2302 58 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 77359192 Common rplL 50S ribosomal subunit protein L7/L12 PSHAa0221 215 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 77359459 Nonpathogen pspC phage shock protein C PSHAa0501 1 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 77360897 Common - hypothetical protein PSHAa1972 10 None None None 77359056 Common - hydrolase PSHAa0079 69 COG2366 COG2366, Protein related to penicillin acylase General function prediction only 77360231 Common trpA tryptophan synthase, alpha protein PSHAa1288 213 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 77359199 Common pck phosphoenolpyruvate carboxykinase PSHAa0228 97 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 77360151 Common adk adenylate kinase PSHAa1208 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 77360554 Common - ABC-type transport system, permease component PSHAa1613 215 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 77361198 Common - TonB-dependent Outer membrane receptor PSHAa2275 124 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 77361629 Common aroB dehydroquinate synthase PSHAa2714 207 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 77359163 Common pabA glutamine amidotransferase PSHAa0192 237 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 77359920 Common - with YjgF-like domain highly conserved in gamma-proteobacteria PSHAa0974 144 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 77360381 Common - hypothetical protein PSHAa1438 65 COG4301 COG4301, Uncharacterized conserved protein Function unknown 77361310 Common - two-component sensor histidine kinase and response regulator hybrid PSHAa2394 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77361024 Nonpathogen - hypothetical protein PSHAa2100 1 None None None 77360028 Common - hypothetical protein PSHAa1085 8 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 77361189 Common - hypothetical protein PSHAa2266 9 None None None 77359630 Common - hypothetical protein PSHAa0678 58 COG3825 COG3825, Uncharacterized protein conserved in bacteria Function unknown 162139933 Common gppA guanosine pentaphosphate phosphohydrolase PSHAa0115 179 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 77361782 Common endA Endonuclease I Precursor (Endo I) PSHAa2879 26 COG2356 EndA, Endonuclease I DNA replication, recombination, and repair 77361336 Common - hypothetical protein PSHAa2420 29 COG1714 COG1714, Predicted membrane protein/domain Function unknown 77360771 Common - AhpC-TSA PSHAa1831 87 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 77360547 Common bioD desthiobiotin synthetase PSHAa1606 105 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 77360319 Common - hypothetical protein PSHAa1376 13 COG0782 GreA, Transcription elongation factor Transcription 77359185 Common - sugar-phosphate aldolase PSHAa0214 135 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 77360085 Common - hypothetical protein PSHAa1142 26 None None None 77359264 Nonpathogen - hypothetical protein PSHAa0297 1 None None None 77360107 Common - NUDIX hydrolase domain PSHAa1164 123 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 77359422 Common - hypothetical protein PSHAa0457 14 None None None 77361673 Nonpathogen - hypothetical protein PSHAa2758 1 None None None 77360357 Common fklB FKBP-type 22KD peptidyl-prolyl cis-trans isomerase (rotamase) PSHAa1414 135 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 77361772 Common - Cytochrome c oxidase subunit III PSHAa2869 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 77361759 Common - hypothetical protein PSHAa2856 5 None None None 77359368 Common - hypothetical protein PSHAa0402 51 None None None 77360629 Common rluE ribosomal large subunit pseudouridine synthase E (Pseudouridylate synthase) (Uracil hydrolyase) PSHAa1688 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 77360576 Common seqA replication initiation regulator SeqA PSHAa1635 23 COG3057 SeqA, Negative regulator of replication initiationR DNA replication, recombination, and repair 77361422 Common mraY phospho-N-acetylmuramoyl-pentapeptide transferase PSHAa2507 213 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 77359083 Nonpathogen - hypothetical protein PSHAa0106 1 COG3895 COG3895, Predicted periplasmic protein General function prediction only 77360795 Common - cytochrome (Hypothetical) PSHAa1855 55 COG2863 COG2863, Cytochrome c553 Energy production and conversion 77361384 Nonpathogen - hypothetical protein PSHAa2469 1 None None None 77359593 Common - hypothetical protein PSHAa0640 8 None None None 77361033 Common - phage integrase PSHAa2110 120 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 77361596 Common mreC rod shape-determining protein (partial) PSHAa2681 146 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 77361383 Common - hypothetical protein PSHAa2467 33 COG3124 COG3124, Uncharacterized protein conserved in bacteria Function unknown 77359160 Common glpD glycerol-3-phosphate dehydrogenase PSHAa0189 149 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 77360020 Nonpathogen aaeX hypothetical protein PSHAa1077 5 None None None 77359220 Common porA disulfide bond formation protein PSHAa0249 63 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 77360571 Common dbT dihydrolipoamide acetyltransferase PSHAa1630 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 77360808 Common pal required for outer membrane integrity, uptake of group A colicins, and translocation of phage DNA PSHAa1870 148 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 77359217 Common - hypothetical protein PSHAa0246 81 COG0348 NapH, Polyferredoxin Energy production and conversion 77360953 Common ecfE membrane-associated protease PSHAa2029 212 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 77360168 Common - hypothetical protein PSHAa1225 14 None None None 77359929 Common aroC chorismate synthase PSHAa0983 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 77361472 Common - mechanosensitive channel protein PSHAa2557 187 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 77359806 Common - SpoOM-related protein PSHAa0857 20 COG4326 Spo0M, Sporulation control protein General function prediction only 77360604 Common - hypothetical protein PSHAa1663 50 COG3216 COG3216, Uncharacterized protein conserved in bacteria Function unknown 77359202 Common gspC general secretion pathway protein C PSHAa0231 27 COG3031 PulC, Type II secretory pathway, component PulC Intracellular trafficking and secretion 77361810 Common - enzyme with alpha/beta-hydrolase domain PSHAa2908 71 COG0429 COG0429, Predicted hydrolase of the alpha/beta-hydrolase fold General function prediction only 77360935 Common - GGDEF domain protein PSHAa2011 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 77360471 Nonpathogen - hypothetical protein PSHAa1530 1 None None None 77359719 Common flgB flagellar biosynthesis; cell-proximal portion of basal-body rod PSHAa0769 90 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 77359471 Common fldB flavodoxin FldB PSHAa0513 65 COG0716 FldA, Flavodoxins Energy production and conversion 77361796 Common leuB 3-isopropylmalate dehydrogenase PSHAa2893 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 77360874 Common - Transcriptional regulator, LysR PSHAa1942 179 COG0583 LysR, Transcriptional regulator Transcription 77359705 Common - hypothetical protein PSHAa0754 10 COG1462 CsgG, Uncharacterized protein involved in formation of curli polymers Cell envelope biogenesis, outer membrane 77360703 Common - urease accessory protein (ureJ) PSHAa1763 47 COG2370 HupE, Hydrogenase/urease accessory protein Posttranslational modification, protein turnover, chaperones 77360296 Common - tryptophan halogenase PSHAa1353 16 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 77359020 Common - hypothetical protein PSHAa0042 22 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 77359466 Common - hypothetical protein PSHAa0508 73 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 77359073 Common - hypothetical protein PSHAa0096 94 COG0400 COG0400, Predicted esterase General function prediction only 77361575 Common - hypothetical protein PSHAa2660 49 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 77359241 Common hflC hypothetical protein PSHAa0274 206 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 77360831 Common - Sigma-54 dependent transcriptional regulator/sensory box protein PSHAa1893 175 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 77360242 Common - hypothetical protein PSHAa1299 6 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 77360870 Common aspS aspartate tRNA synthetase PSHAa1938 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 77361010 Nonpathogen - hypothetical protein PSHAa2086 1 None None None 77359781 Common - EAL domain PSHAa0832 49 COG3434 COG3434, Predicted signal transduction protein containing EAL and modified HD-GYP domains Signal transduction mechanisms 77360117 Nonpathogen - hypothetical protein PSHAa1174 1 None None None 77360779 Common - hypothetical protein PSHAa1839 7 COG4083 COG4083, Predicted membrane protein Function unknown 77360131 Common - MotA/TolQ/ExbB proton channel protein PSHAa1188 18 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 77359339 Common - lysophospholipase PSHAa0373 69 COG2267 PldB, Lysophospholipase Lipid metabolism 77359526 Common - alginate lyase PSHAa0571 6 None None None 77360664 Common clpA ATP-dependent specificity subunit of clpA-clpP serine protease PSHAa1724 221 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 77360038 Common - hypothetical protein PSHAa1095 49 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 77359374 Common - hypothetical protein PSHAa0408 4 None None None 77359664 Common - hypothetical protein PSHAa0713 42 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 77360197 Common - 2-hydroxy-3-oxopropionate reductase PSHAa1254 163 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 77361501 Common - L-sorbosone dehydrogenase (SNDH) PSHAa2586 63 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 77360094 Common - two-component member protein PSHAa1151 223 COG3300 COG3300, MHYT domain (predicted integral membrane sensor domain) Signal transduction mechanisms 77359987 Common - plasmid stabilization system protein PSHAa1041 8 COG3668 ParE, Plasmid stabilization system protein General function prediction only 77361707 Common trmH tRNA guanosine-2'-O-methyltransferase PSHAa2798 183 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 77359982 Common - hypothetical protein ; membrane protein PSHAa1036 11 None None None 77361405 Common - hypothetical protein PSHAa2490 11 None None None 77360695 Common - pirin-related protein PSHAa1755 143 COG1741 COG1741, Pirin-related protein General function prediction only 77360154 Common - sensory box/GGDEF protein PSHAa1211 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 77361666 Common - hypothetical protein PSHAa2751 23 COG3078 COG3078, Uncharacterized protein conserved in bacteria Function unknown 77360393 Common - enoyl-CoA hydratase/isomerase PSHAa1450 176 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 162139922 Common - putative chaperone PSHAa2176 234 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 77361038 Common motY Component of sodium-driven polar flagellar motor PSHAa2115 118 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 77359681 Common lepA GTP-binding protein LepA PSHAa0730 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 77359712 Common - hypothetical protein PSHAa0762 18 COG3018 COG3018, Uncharacterized protein conserved in bacteria Function unknown 77358995 Common pepQ Xaa-Pro proline dipeptidase PSHAa0013 116 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 77359035 Common - hypothetical protein PSHAa0058 154 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 77361766 Common - polysaccharide deacetylase protein PSHAa2863 108 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 77360824 Common - hypothetical protein PSHAa1886 6 None None None 77361127 Common - hypothetical protein PSHAa2204 46 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 77359401 Common araC transcriptional regulator PSHAa0435 54 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77360686 Common - hexuronate transport protein (MFS) PSHAa1746 126 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 77361045 Common - hypothetical protein PSHAa2122 29 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 77359051 Common folM short chain dehydrogenase PSHAa0074 207 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77361174 Common - HesB/YadR/YfhF protein PSHAa2251 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 77359648 Common - hypothetical protein PSHAa0696 26 None None None 77361809 Nonpathogen - hypothetical protein PSHAa2907 1 None None None 77361802 Common rsd anti-RNA polymerase sigma 70 factor PSHAa2900 24 COG3160 Rsd, Regulator of sigma D Transcription 77359643 Common rpoS sigma S (sigma 38) factor of RNA polymerase, major sigma factor during stationary phase PSHAa0691 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 77361263 Nonpathogen - hypothetical protein PSHAa2346 1 None None None 77360915 Common dinG ATP-dependent DNA helicase DinG PSHAa1991 129 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 77361205 Common coaD Phosphopantetheine adenylyltransferase (PPAT) (Dephospho-CoA pyrophosphorylase) PSHAa2282 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 77361101 Common - enzymatic protein PSHAa2178 187 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 77359815 Common - hypothetical protein PSHAa0866 7 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 77359740 Common fliE flagellar biosynthesis; basal-body component PSHAa0791 83 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 77361820 Common - transcriptional regulator PSHAa2918 128 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 77359853 Common - enoyl-CoA hydratase PSHAa0905 170 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 77360214 Common - TonB-dependent receptor PSHAa1271 94 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 77360504 Common - hypothetical protein PSHAa1563 40 COG4325 COG4325, Predicted membrane protein Function unknown 77359556 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase PSHAa0602 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 77359788 Common ahpCB peroxiredoxin 2 (Thioredoxin peroxidase 1) (Thioredoxin-dependent peroxide reductase 1) (Thiol-specific antioxidant protein) (TSA) (PRP) PSHAa0839 224 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 77361245 Common - hypothetical protein PSHAa2322 18 None None None 77361146 Common - putativeB12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase (N terminal) PSHAa2223 164 COG0646 MetH, Methionine synthase I (cobalamin-dependent), methyltransferase domain Amino acid transport and metabolism 77361624 Common gph phosphoglycolate phosphatase, contains a phosphatase-like domain PSHAa2709 186 COG0546 Gph, Predicted phosphatases General function prediction only 77361754 Common greB transcription elongation factor and transcript cleavage PSHAa2851 190 COG0782 GreA, Transcription elongation factor Transcription 77361618 Common - hypothetical protein PSHAa2703 14 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 77360125 Common - hypothetical protein ; GGDEF protein PSHAa1182 180 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 77359836 Common - lipid-transfer protein PSHAa0887 90 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 77361841 Nonpathogen - hypothetical protein PSHAa2939 1 None None None 77360540 Common - Soj protein, ATPase involved in chromosome partitioning PSHAa1599 205 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 77360933 Common - hypothetical protein PSHAa2009 39 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 77361393 Common - TonB-dependent receptor protein PSHAa2478 114 COG4772 FecA, Outer membrane receptor for Fe3+-dicitrate Inorganic ion transport and metabolism 77360110 Common bcd Leucine dehydrogenase PSHAa1167 154 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 77359562 Common pepB aminopeptidase B PSHAa0608 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 77361075 Nonpathogen - hypothetical protein ; signal peptide PSHAa2152 1 None None None 77361233 Common ubiA 4-hydroxybenzoate octaprenyltransferase PSHAa2310 187 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 77359298 Common - hypothetical protein PSHAa0331 47 COG3045 CreA, Uncharacterized protein conserved in bacteria Function unknown 77359379 Common - hypothetical protein PSHAa0413 19 None None None 77361084 Common - protein yhjQ PSHAa2161 16 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 77360377 Common - hypothetical protein PSHAa1434 120 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 77359397 Nonpathogen - hypothetical protein PSHAa0431 1 None None None 77360347 Common - hypothetical protein PSHAa1404 102 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 77360394 Common - beta subunit of a coenzyme A carboxylase protein PSHAa1451 143 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 77361320 Common - hypothetical protein ; histidine-rich domain PSHAa2404 3 None None None 77361642 Nonpathogen - hypothetical protein PSHAa2727 1 None None None 77359361 Common - aerotaxis sensory transducer PSHAa0395 162 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77361161 Common nqrD Na(+)-translocating NADH-quinone reductase subunit D PSHAa2238 76 COG1347 NqrD, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD Energy production and conversion 77360984 Common lon DNA-binding ATP-dependent protease La; heat shock K-protein PSHAa2060 219 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 77359872 Common - hypothetical protein PSHAa0925 14 COG4966 PilW, Tfp pilus assembly protein PilW Cell motility and secretion / Intracellular trafficking and secretion 77361285 Common thiL thiamin-monophosphate kinase PSHAa2369 206 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 77360835 Common - hypothetical protein PSHAa1897 4 COG4640 COG4640, Predicted membrane protein Function unknown 77361545 Common - Mannose-1-phosphate guanyltransferase-related protein PSHAa2630 220 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 77361274 Common - hypothetical protein PSHAa2358 7 None None None 77359103 Common - two-component response regulator PSHAa0131 207 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77360502 Common - hypothetical protein PSHAa1561 4 None None None 77360257 Common - hypothetical protein PSHAa1314 21 None None None 77360615 Common - hypothetical protein PSHAa1674 18 None None None 77359390 Nonpathogen - hypothetical protein PSHAa0424 1 None None None 77361897 Common - carbohydrate o-acetyltransferase PSHAa2996 122 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 77361291 Common ribX hypothetical protein PSHAa2375 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 77361445 Common - Ubiquinol-cytochrome c reductase, iron-sulfur subunit PSHAa2530 90 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 77360829 Common - hypothetical protein PSHAa1891 13 COG3608 COG3608, Predicted deacylase General function prediction only 77360609 Common ycbW hypothetical protein PSHAa1668 17 None None None 77360102 Nonpathogen - hypothetical protein PSHAa1159 1 COG5404 SulA, SOS-response cell division inhibitor, blocks FtsZ ring formation Cell division and chromosome partitioning 77360384 Common - Pyrrolidone-carboxylate peptidase (5-oxoprolyl-peptidase) (Pyroglutamyl-peptidase I) (PGP-I) (Pyrase) PSHAa1441 58 COG2039 Pcp, Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) Posttranslational modification, protein turnover, chaperones 77360995 Common cvpA membrane protein required for colicin V production PSHAa2071 47 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 77359494 Nonpathogen - hypothetical protein PSHAa0537 1 COG5487 COG5487, Small integral membrane protein Function unknown 77360789 Common - hypothetical protein PSHAa1849 64 COG2836 COG2836, Uncharacterized conserved protein Function unknown 77360274 Common dapE succinyl-diaminopimelate desuccinylase PSHAa1331 206 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 77360673 Common - hypothetical protein PSHAa1733 16 None None None 77360758 Common - hypothetical protein PSHAa1818 21 COG3082 COG3082, Uncharacterized protein conserved in bacteria Function unknown 77359406 Nonpathogen - hypothetical protein PSHAa0441 1 None None None 77361717 Common rpsE 30S ribosomal protein S5 PSHAa2813 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 77359132 Common - hypothetical protein PSHAa0160 3 None None None 77361710 Common rpoA DNA-directed RNA polymerase subunit alpha PSHAa2806 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 77361842 Common - elongation factor G PSHAa2940 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 77361481 Common fhuC Iron-compound ABC transporter ATP-binding protein PSHAa2566 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 77360223 Common - hypothetical protein PSHAa1280 35 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 77361371 Common gssA bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase PSHAa2455 56 COG0754 Gsp, Glutathionylspermidine synthase Amino acid transport and metabolism 77361431 Nonpathogen - hypothetical protein PSHAa2516 1 None None None 77360751 Common rpmF 50S ribosomal protein L32 PSHAa1811 100 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 77360833 Common - hypothetical protein PSHAa1895 17 None None None 77361492 Common rimK ribosomal protein S6 modification protein PSHAa2577 158 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 77361142 Common - hypothetical protein PSHAa2219 6 None None None 77359112 Common - hypothetical protein PSHAa0140 94 COG2947 COG2947, Uncharacterized conserved protein Function unknown 77360266 Common yfbQ aminotransferase AlaT PSHAa1323 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 77359696 Common nudH dinucleoside polyphosphate hydrolase PSHAa0745 116 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 77360362 Common - phosphoglycolate phosphatase, contains a phosphatase-like domain PSHAa1419 139 COG0546 Gph, Predicted phosphatases General function prediction only 77359999 Common - Outer membrane lipoprotein LolB PSHAa1056 23 COG3017 LolB, Outer membrane lipoprotein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 77360051 Nonpathogen - hypothetical protein PSHAa1108 1 None None None 77359219 Common dsbA disulfide bond formation protein PSHAa0248 61 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 77360593 Nonpathogen - hypothetical protein PSHAa1652 1 None None None 77360740 Common - metallo-dependent hydrolase PSHAa1800 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 77361180 Common - Ammonium/methylammonium transporter amtB PSHAa2257 203 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 77359139 Common typA GTP-binding protein PSHAa0167 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 77360649 Nonpathogen - hypothetical protein PSHAa1708 1 None None None 77359062 Common - ribosomal RNA pseudouridylate synthase PSHAa0085 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 77359524 Common - hypothetical protein PSHAa0569 4 None None None 77360642 Common - hypothetical protein PSHAa1701 3 COG3686 COG3686, Predicted membrane protein Function unknown 77360969 Common - hypothetical protein PSHAa2045 42 COG3768 COG3768, Predicted membrane protein Function unknown 77361089 Common - proton-dependent peptide transporter PSHAa2166 82 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 77360773 Common - hypothetical protein PSHAa1833 9 None None None 77361395 Common rnr RNase R, 3'-5' exoribonuclease PSHAa2480 201 COG0557 VacB, Exoribonuclease R Transcription 77359481 Common - hypothetical protein PSHAa0524 7 COG2039 Pcp, Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) Posttranslational modification, protein turnover, chaperones 77361739 Common - hypothetical protein PSHAa2835 36 None None None 77361359 Common rpsF 30S ribosomal protein S6 PSHAa2443 199 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 77361457 Common - transport protein (ABC superfamily, periplasmic binding component) PSHAa2542 68 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 77358988 Common glyS glycyl-tRNA synthetase subunit beta PSHAa0006 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 77360960 Common rpsB 30S ribosomal subunit protein S2 PSHAa2036 234 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 77359979 Common - ATP-dependent protease PSHAa1033 170 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 77360391 Common hmgcL Hydroxymethylglutaryl-CoA lyase (HMG-CoA lyase) (HL) (3-hydroxy-3-methylglutarate-CoA lyase) PSHAa1448 189 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 77361724 Common rplN 50S ribosomal subunit protein L14 PSHAa2820 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 77361833 Common tatC twin-arginine translocase subunit, sec-independent protein export PSHAa2931 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 77360989 Common cysS cysteinyl-tRNA synthetase PSHAa2065 242 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 77359317 Common - hypothetical protein PSHAa0351 150 COG1610 COG1610, Uncharacterized conserved protein Function unknown 77361307 Common - thioesterase protein PSHAa2391 53 COG0824 FcbC, Predicted thioesterase General function prediction only 77361516 Common - Holliday junction resolvase-like protein PSHAa2601 174 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 77359230 Common dipZ thiol:disulfide interchange protein precursor PSHAa0263 106 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 77359146 Common pldA phospholipase A precursor PSHAa0175 52 COG2829 PldA, Outer membrane phospholipase A Cell envelope biogenesis, outer membrane 77360670 Common - hypothetical protein PSHAa1730 3 None None None 77360782 Common - Cytochrome c oxidase, cbb3-type, subunit I PSHAa1842 143 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 77360941 Common lpxB tetraacyldisaccharide-1-P synthase PSHAa2017 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 77359270 Common - cation efflux protein PSHAa0303 51 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 77361410 Common prkB phosphoribulokinase PSHAa2495 51 COG3954 PrkB, Phosphoribulokinase Energy production and conversion 77359952 Common - putative monovalent cation/H+ antiporter subunit D PSHAa1006 207 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 77360977 Common sapC peptide transport protein (ABC superfamily, membrane) PSHAa2053 218 COG4171 SapC, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 77360802 Common - TonB-dependent receptor PSHAa1862 41 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 77359541 Common - hypothetical protein PSHAa0586 52 COG4327 COG4327, Predicted membrane protein Function unknown 77361746 Common - Chromate/sulfate transporter PSHAa2843 113 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 77360572 Common bkdA2 2-oxoisovalerate dehydrogenase beta subunit (Branched-chain alpha-keto acid dehydrogenase E1 component beta chain) (BCKDH E1-beta) PSHAa1631 191 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 77359840 Common - 2O-beta-hydroxysteroid dehydrogenase PSHAa0891 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77359779 Common - cytochrome c-type biogenesis protein PSHAa0830 55 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 77361452 Common degS periplasmic serine endoprotease PSHAa2537 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 77359887 Common - hypothetical protein PSHAa0940 73 COG4137 COG4137, ABC-type uncharacterized transport system, permease component General function prediction only 77361527 Common - hypothetical protein PSHAa2612 28 COG2859 COG2859, Uncharacterized protein conserved in bacteria Function unknown 77361105 Common - mechanosensitive ion channel PSHAa2182 222 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 77359975 Common holA DNA polymerase III subunit delta PSHAa1029 80 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 77360115 Nonpathogen - hypothetical protein PSHAa1172 3 None None None 77358997 Common trkH potassium transport protein PSHAa0015 129 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 77359175 Nonpathogen - hypothetical protein PSHAa0204 1 None None None 77361825 Common - Glutamate synthase GltB PSHAa2923 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 77360978 Common sapD peptide transport protein (ABC superfamily, atp_bind) PSHAa2054 249 COG4170 SapD, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 77361115 Common - putative glutathione S-transferase YghU PSHAa2192 96 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 77361838 Common - periplasmic calcium binding protein PSHAa2936 51 COG2374 COG2374, Predicted extracellular nuclease General function prediction only 77361415 Common ftsA Cell division protein PSHAa2500 179 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 77360645 Nonpathogen - hypothetical protein PSHAa1704 1 None None None 77359828 Common - 3-oxoacyl-(ACP) reductase PSHAa0879 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77360288 Common sohB predicted inner membrane peptidase PSHAa1345 189 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 77361464 Common - transport protein (ABC superfamily, periplasmic binding component) PSHAa2549 34 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 77359533 Common czcB Cobalt-zinc-cadmium resistance protein ; (cation efflux system protein) PSHAa0578 114 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 77360809 Common tolB required for outer membrane integrity, uptake of group A colicins, and translocation of phage DNA PSHAa1871 155 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 77361859 Common - multidrug resistance protein, AcrB/AcrD/AcrF PSHAa2957 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 77359445 Common thiO thiamine biosynthesis oxidoreductase PSHAa0481 73 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 77361819 Common hit member of HIT (histidine triad) that contains Ap3A and Ap4A hydrolase PSHAa2917 231 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 77360845 Common - sodium:alanine symporter PSHAa1913 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 77359247 Common proA gamma-glutamyl phosphate reductase PSHAa0280 191 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 77359172 Nonpathogen - hypothetical protein PSHAa0201 1 None None None 77360583 Common glnS glutaminyl-tRNA synthetase PSHAa1642 246 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 77359927 Common - hypothetical protein PSHAa0981 41 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 77361064 Common xylJ 2-hydroxypent-2,4-dienoate hydratase (HPH) (2-oxopent-4-enoate hydratase) PSHAa2141 65 COG3971 COG3971, 2-keto-4-pentenoate hydratase Secondary metabolites biosynthesis, transport, and catabolism 77359435 Common - hypothetical protein PSHAa0470 10 None None None 77360002 Common prmC N5-glutamine methyltransferase, modifies release factors RF-1 and RF-2 PSHAa1059 206 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 77360511 Common - hypothetical protein PSHAa1570 121 COG2855 COG2855, Predicted membrane protein Function unknown 77359981 Nonpathogen - hypothetical protein PSHAa1035 1 None None None 77360383 Common asnB asparagine synthetase B PSHAa1440 154 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 77361568 Common folA dihydrofolate reductase type I, trimethoprim resistance PSHAa2653 149 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 77359029 Common - esterase PSHAa0051 36 COG2267 PldB, Lysophospholipase Lipid metabolism 77361901 Common - enzymatic protein PSHAa3000 97 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 77361854 Common - hypothetical protein PSHAa2952 32 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 77361097 Common - amino acid transporter PSHAa2174 122 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 77359555 Common panC pantothenate synthetase PSHAa0601 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 77360192 Nonpathogen - hypothetical protein PSHAa1249 2 None None None 77359905 Common - RNA polymerase sigma factor PSHAa0959 170 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 77360143 Common apt adenine phosphoribosyltransferase PSHAa1200 189 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 77359461 Common - hypothetical protein PSHAa0503 75 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 77360432 Common - transcriptional regulator, TetR PSHAa1489 87 COG1309 AcrR, Transcriptional regulator Transcription 77360019 Common speB agmatinase PSHAa1076 155 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 77361408 Common - hypothetical protein PSHAa2493 4 None None None 77360859 Common - hypothetical protein PSHAa1927 56 COG1432 COG1432, Uncharacterized conserved protein Function unknown 77359793 Common - small protein A [Precursor] (smpA) PSHAa0844 64 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 77360281 Common - hypothetical protein PSHAa1338 18 COG3235 COG3235, Predicted membrane protein Function unknown 77361056 Common tesH 3-ketosteroid-delta1-dehydrogenase PSHAa2133 57 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 77359799 Common - DNA-binding transcriptional regulator IlvY PSHAa0850 183 COG0583 LysR, Transcriptional regulator Transcription 77360495 Common - hypothetical protein PSHAa1554 2 None None None 77361908 Common atpF membrane-bound ATP synthase, F0 sector, subunit b PSHAa3012 144 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 77360490 Nonpathogen - hypothetical protein PSHAa1549 1 None None None 77361177 Common pyrB aspartate carbamoyltransferase PSHAa2254 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 77359075 Common hemC porphobilinogen deaminase PSHAa0098 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 77360659 Common pssA phosphatidylserine synthase PSHAa1719 31 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 77359141 Common - hypothetical protein PSHAa0170 15 None None None 77359821 Common glmM phosphoglucosamine mutase PSHAa0872 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 77360633 Common purB adenylosuccinate lyase PSHAa1692 232 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 77360854 Common - hypothetical protein PSHAa1922 30 None None None 77359733 Common fliD flagellar hook-associated protein PSHAa0784 96 COG1345 FliD, Flagellar capping protein Cell motility and secretion 77359663 Common - Magnesium transporter PSHAa0712 157 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 77359210 Common gspK general secretion pathway protein K PSHAa0239 39 COG3156 PulK, Type II secretory pathway, component PulK Intracellular trafficking and secretion 77360209 Nonpathogen - hypothetical protein PSHAa1266 1 None None None 77360482 Nonpathogen - hypothetical protein PSHAa1541 2 None None None 77359898 Common - translation initiation factor SUI1 PSHAa0952 86 COG0023 SUI1, Translation initiation factor 1 (eIF-1/SUI1) and related proteins Translation, ribosomal structure and biogenesis 77360201 Nonpathogen - hypothetical protein PSHAa1258 2 None None None 77361870 Common - hypothetical protein PSHAa2968 15 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 77360097 Common - hypothetical protein PSHAa1154 4 None None None 77361918 Common yidC preprotein translocase ; inner membrane protein (IMP) integration factor; binds TM regions of nascent IMPs; required for Sec-independent IMP integration; associated with the with SecYEG and SecDFyajC translocase PSHAa3022 215 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 77359399 Nonpathogen - hypothetical protein PSHAa0433 1 None None None 77361889 Nonpathogen - hypothetical protein PSHAa2987 2 None None None 77359019 Common - hypothetical protein PSHAa0041 9 COG3789 COG3789, Uncharacterized protein conserved in bacteria Function unknown 77360404 Common - integrase PSHAa1461 220 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 77360087 Common hrpA helicase, ATP-dependent PSHAa1144 133 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 77359969 Common - Rare lipoprotein A PSHAa1023 137 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 77359392 Nonpathogen - hypothetical protein PSHAa0426 1 None None None 77360722 Common - hypothetical protein PSHAa1782 16 COG5338 COG5338, Uncharacterized protein conserved in bacteria Function unknown 77361531 Nonpathogen - hypothetical protein PSHAa2616 1 None None None 77360308 Common - transcription regulator PSHAa1365 128 COG1609 PurR, Transcriptional regulators Transcription 77361005 Common - conserved protein of unknown function, FAD/NAD(P)-binding domain PSHAa2081 76 COG4121 COG4121, Uncharacterized conserved protein Function unknown 77359610 Common pdxH pyridoxine 5'-phosphate oxidase PSHAa0658 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 77360883 Common - hypothetical protein PSHAa1951 71 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 77361552 Common apaH diadenosine tetraphosphatase PSHAa2637 87 COG3855 Fbp, Uncharacterized protein conserved in bacteria Carbohydrate transport and metabolism 77360317 Common secD preprotein translocase subunit SecD PSHAa1374 215 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 77359046 Common ptrB oligopeptidase PSHAa0069 107 COG1770 PtrB, Protease II Amino acid transport and metabolism 77360761 Common aceK bifunctional isocitrate dehydrogenase kinase/phosphatase protein PSHAa1821 29 COG4579 COG4579, Isocitrate dehydrogenase kinase/phosphatase Signal transduction mechanisms 77359281 Common - inorganic phosphate transporter PSHAa0314 179 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 77359041 Common - amino acid permease PSHAa0064 110 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 77359585 Common - inner membrane protein PSHAa0632 177 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 77359959 Common - hypothetical protein PSHAa1013 10 None None None 77360793 Nonpathogen - hypothetical protein PSHAa1853 1 None None None 77359229 Common cutA C-type cytochrome biogenesis protein PSHAa0262 121 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 77359756 Common flhF flagellar biosynthesis regulator FlhF PSHAa0807 222 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 77359510 Common mutY A/G-specific adenine glycosylase PSHAa0554 227 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 77361582 Common hscA chaperone protein HscA PSHAa2667 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 77359762 Common cheB chemotaxis-specific methylesterase PSHAa0813 198 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 77359519 Common visC monooxygenase, FAD/NAD(P)-binding domain PSHAa0564 132 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 77359351 Nonpathogen - hypothetical protein PSHAa0385 1 None None None 77360516 Common - outer membrane porin PSHAa1575 19 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 77361152 Common cyoC cytochrome o ubiquinol oxidase subunit III (Ubiquinol oxidase chain C) PSHAa2229 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 77361538 Nonpathogen - hypothetical protein PSHAa2623 1 None None None 77359284 Common - hypothetical protein PSHAa0317 180 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 77360739 Common - hypothetical protein PSHAa1799 22 None None None 77361633 Common pilO Type IV pilus biogenesis protein PilO PSHAa2718 47 COG3167 PilO, Tfp pilus assembly protein PilO Cell motility and secretion / Intracellular trafficking and secretion 77359310 Common - hypothetical protein PSHAa0344 22 COG4798 COG4798, Predicted methyltransferase General function prediction only 77359908 Common - Von Willebrand factor type A PSHAa0962 84 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 77360120 Common - hypothetical protein PSHAa1177 7 None None None 77359332 Common gpmM phosphoglyceromutase PSHAa0366 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 77360303 Nonpathogen - hypothetical protein ; membrane-associated protein PSHAa1360 1 None None None 77359722 Common flgE flagellar hook protein FlgE PSHAa0772 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 77360146 Common recR recombination protein recR PSHAa1203 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 77359147 Nonpathogen - hypothetical protein PSHAa0176 1 None None None 77360379 Common - Choline-glycine betaine transporter PSHAa1436 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 77361590 Common tldD suppressor of CsrA inhibitory activity; peptidase; involved in the control of DNA gyrase PSHAa2675 170 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 77359835 Common - hypothetical protein PSHAa0886 11 None None None 77361483 Common hdfR transcriptional regulator PSHAa2568 183 COG0583 LysR, Transcriptional regulator Transcription 77359971 Common mrdA cell elongation-specific transpeptidase of penicillin-binding protein 2 (peptidoglycan synthetase) PSHAa1025 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 77361506 Common nudF ADP-ribose pyrophosphatase (ADP-ribose diphosphatase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (ADP-ribose phosphohydrolase) (ASPPase) PSHAa2591 76 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 77361400 Common - 4Fe-4S ferredoxin PSHAa2485 134 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 77361167 Common - 2OG-Fe(II) oxygenase superfamily protein PSHAa2244 42 COG3145 AlkB, Alkylated DNA repair protein DNA replication, recombination, and repair 77359985 Common - hypothetical protein PSHAa1039 18 None None None 77360817 Common - Lipoprotein releasing system ATP-binding component of ABC transporter PSHAa1879 249 COG4181 COG4181, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 77359603 Common lmrb Lincomycin resistance protein lmrB PSHAa0650 175 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77360759 Common - hypothetical protein PSHAa1819 27 COG3083 COG3083, Predicted hydrolase of alkaline phosphatase superfamily General function prediction only 77359639 Common surE acid phosphatase surE PSHAa0687 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 77360627 Nonpathogen - hypothetical protein PSHAa1686 1 COG2168 DsrH, Uncharacterized conserved protein involved in oxidation of intracellular sulfur Inorganic ion transport and metabolism 77360919 Nonpathogen - hypothetical protein PSHAa1995 1 None None None 77359333 Common - rhodanese sulfur transferase PSHAa0367 77 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 77359180 Common cysC adenosine 5'-phosphosulfate kinase PSHAa0209 144 COG0529 CysC, Adenylylsulfate kinase and related kinases Inorganic ion transport and metabolism 77360136 Nonpathogen - hypothetical protein PSHAa1193 1 COG4805 COG4805, Uncharacterized protein conserved in bacteria Function unknown 77359559 Common queB glutamyl-Q tRNA(Asp) synthetase PSHAa0605 242 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 77361702 Common spoT bifunctional: (p)ppGpp synthetase II; guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase PSHAa2793 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 77359856 Common - acetyl-CoA acetyltransferase PSHAa0908 186 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 77359966 Common lipB Lipoate-protein ligase B PSHAa1020 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 77361539 Common hepA ATP-dependent helicase HepA PSHAa2624 135 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 77361551 Common apaG ApaG PSHAa2636 88 COG2967 ApaG, Uncharacterized protein affecting Mg2+/Co2+ transport Inorganic ion transport and metabolism 77360076 Common - arsenate reductase PSHAa1133 115 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 77359480 Common - Na+/H+ antiporter PSHAa0523 74 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 77360763 Common - hypothetical protein PSHAa1823 6 None None None 77361236 Common - GlpG protein PSHAa2313 73 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 77359022 Common - hypothetical protein PSHAa0044 6 None None None 77360681 Nonpathogen - hypothetical protein PSHAa1741 1 None None None 77361297 Common rdgC recombination associated protein PSHAa2381 53 COG2974 RdgC, DNA recombination-dependent growth factor C DNA replication, recombination, and repair 77360812 Common tolQ inner membrane protein required for outer membrane integrity, uptake of group A colicins and phage DNA PSHAa1874 150 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 77360254 Common - hypothetical protein PSHAa1311 32 COG3011 COG3011, Uncharacterized protein conserved in bacteria Function unknown 77359787 Common fadR fatty acid metabolism regulator PSHAa0838 84 COG2186 FadR, Transcriptional regulators Transcription 77360827 Common - hypothetical protein PSHAa1889 4 None None None 77359780 Common vacJ lipoprotein precursor PSHAa0831 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 77359586 Common proB gamma-glutamyl kinase PSHAa0633 189 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 77360127 Common cspC cold shock protein, transcription antiterminator, affects expression of rpoS and uspA PSHAa1184 180 COG1278 CspC, Cold shock proteins Transcription 77359098 Common - hydrolase PSHAa0126 38 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 77361774 Common ctaD Cytochrome c oxidase, subunit I PSHAa2871 174 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 77361287 Common ribH 6,7-dimethyl-8-ribityllumazine synthase PSHAa2371 230 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 77360663 Common infA translation initiation factor IF-1 PSHAa1723 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 77359599 Nonpathogen - hypothetical protein PSHAa0646 1 None None None 77361611 Common mshK Mannose-sensitive agglutinin (MSHA) biogenesis protein MshK (pilus type IV), lipoprotein PSHAa2696 5 None None None 77359536 Common - transposase PSHAa0581 64 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 77361272 Common topB DNA topoisomerase III PSHAa2356 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 77359125 Common rpsQ 30S ribosomal subunit protein S17 PSHAa0153 228 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 77361843 Common - transcriptional regulator sensing dicarboxylates PSHAa2941 40 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 77359275 Common - hypothetical protein PSHAa0308 30 COG2716 GcvR, Glycine cleavage system regulatory protein Amino acid transport and metabolism 77360156 Common - hypothetical protein PSHAa1213 71 COG2718 COG2718, Uncharacterized conserved protein Function unknown 77359520 Common - transcriptional regulator PSHAa0565 62 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77360928 Nonpathogen - conserved protein of unknown function; some similarity with a Photorhabdus luminescens membrane protein of unknown function PSHAa2004 1 None None None 77360036 Common fbaA fructose-bisphosphate aldolase PSHAa1093 169 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 77360899 Common - Acetyltransferase, GNAT PSHAa1975 7 COG0456 RimI, Acetyltransferases General function prediction only 77361491 Common - hypothetical protein PSHAa2576 54 COG3608 COG3608, Predicted deacylase General function prediction only 77361664 Common hemN coproporphyrinogen III oxidase PSHAa2749 204 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 77361902 Common glmU bifunctional: N-acetyl glucosamine-1-phosphate uridyltransferase (N-terminal); glucosamine-1-phosphate acetyl transferase (C-terminal) PSHAa3006 231 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 77359345 Common coaE dephospho-CoA kinase PSHAa0379 207 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 77359765 Common - partitioning protein A PSHAa0816 230 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 77361121 Common - hypothetical protein PSHAa2198 10 None None None 77359855 Common - butyryl-CoA dehydrogenase PSHAa0907 129 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77360796 Common - hypothetical protein PSHAa1856 100 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 77361416 Common ftsQ cell division protein PSHAa2501 83 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 77360838 Common gapA glyceraldehyde-3-phosphate dehydrogenase PSHAa1900 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 77359502 Common - cobalamin biosynthesis protein PSHAa0546 57 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 77359625 Common - ribosomal subunit interface protein, similar to protein Y PSHAa0673 70 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 77359814 Common ampC beta-lactamase precursor PSHAa0865 133 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 77361909 Common atpE membrane-bound ATP synthase, F0 sector, subunit c PSHAa3013 122 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 77360328 Common - esterase PSHAa1385 102 COG0627 COG0627, Predicted esterase General function prediction only 77361444 Common - ubiquinol-cytochrome c reductase, cytochrome B PSHAa2529 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 77359252 Common - cytochrome c4 PSHAa0285 53 COG2863 COG2863, Cytochrome c553 Energy production and conversion 77360917 Common - hypothetical protein PSHAa1993 17 COG3923 PriC, Primosomal replication protein N'' DNA replication, recombination, and repair 77359708 Common - dihydrolipoamide dehydrogenase PSHAa0758 235 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 77360890 Common - S-adenosyl-L-methionine-dependent methyltransferase PSHAa1965 58 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 77361647 Common - hypothetical protein PSHAa2732 49 COG3536 COG3536, Uncharacterized protein conserved in bacteria Function unknown 77359996 Common rplY 50S ribosomal protein L25 PSHAa1053 194 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 77359383 Common - hypothetical protein PSHAa0417 33 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 77361449 Common yhcM ATPase PSHAa2534 101 COG1485 COG1485, Predicted ATPase General function prediction only 77360388 Common - transcriptional regulator (positive) of LysR PSHAa1445 175 COG0583 LysR, Transcriptional regulator Transcription 77360556 Common - hypothetical protein PSHAa1615 6 COG4088 COG4088, Predicted nucleotide kinase Nucleotide transport and metabolism 77360610 Common pyrD dihydro-orotate oxidase, FMN-linked PSHAa1669 236 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 77360910 Common - prolyl oligopeptidase PSHAa1986 126 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 77359714 Common flgM negative regulator of flagellin synthesis PSHAa0764 10 COG2747 FlgM, Negative regulator of flagellin synthesis (anti-sigma28 factor) Transcription / Cell motility and secretion / Intracellular trafficking and secretion 77360374 Common - hypothetical protein PSHAa1431 44 COG2996 COG2996, Uncharacterized protein conserved in bacteria Function unknown 77359340 Common - sensor histidine kinase protein PSHAa0374 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77361601 Common mshO Mannose-sensitive agglutinin (MSHA) biogenesis protein MshO (pilus type IV) PSHAa2686 14 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 77359876 Common - Type IV pilus biogenesis protein PSHAa0929 18 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 77359158 Common - hypothetical protein PSHAa0187 10 None None None 77361765 Common - DNA-damage-inducible protein F PSHAa2862 148 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 77360912 Common - S-adenosyl-L-methionine-dependent methyltransferase PSHAa1988 3 COG0500 SmtA, SAM-dependent methyltransferases Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77360506 Common sfcA NAD-linked malate dehydrogenase PSHAa1565 202 COG0281 SfcA, Malic enzyme Energy production and conversion 162139925 Common pheT phenylalanyl-tRNA synthetase subunit beta PSHAa1903 248 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 77360344 Common - enzyme with metallo-hydrolase/oxidoreductase domain PSHAa1401 214 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 77360697 Common ureA urease subunit gamma PSHAa1757 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 77361077 Common - efflux pump PSHAa2154 188 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 77360241 Common - hypothetical protein PSHAa1298 120 COG2353 COG2353, Uncharacterized conserved protein Function unknown 77359356 Common pdhR transcriptional regulator PdhR PSHAa0390 149 COG2186 FadR, Transcriptional regulators Transcription 77359000 Nonpathogen - calmodulin PSHAa0018 1 None None None 77360937 Common tilS lysidine forming enzyme PSHAa2013 188 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 77360429 Common - hypothetical protein PSHAa1486 4 None None None 77361381 Common - hypothetical protein PSHAa2465 26 None None None 77361672 Common polA multifunctional DNA polymerase I: 5'->3' exonuclease (N-terminal); 3'->5' polymerase; 3'->5' exonuclease (C-terminal) PSHAa2757 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 77360780 Common - TonB-dependent receptor PSHAa1840 110 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 77359424 Common sseA 3-mercaptopyruvate sulfurtransferase PSHAa0459 144 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 77360171 Common carA carbamoyl phosphate synthetase, glutamine amidotransferase small subunit PSHAa1228 234 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 77361757 Common yhgF conserved protein with nucleic acid-binding protein-like domain (Transcriptional accessory protein) PSHAa2854 214 COG2183 Tex, Transcriptional accessory protein Transcription 77359847 Common - acyl dehydratase PSHAa0898 91 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 77361479 Common cobQ cobyric acid synthase PSHAa2564 150 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 77361470 Common npr phosphocarrier protein NPr (HPr-like), nitrogen-related PSHAa2555 131 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 77360730 Common - hypothetical protein PSHAa1790 38 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 77360007 Common gcvA DNA-binding transcriptional activator GcvA PSHAa1064 185 COG0583 LysR, Transcriptional regulator Transcription 77360930 Common - conserved protein of unknown function; some similarity with unknown proteins of Firmicutes PSHAa2006 9 COG4469 CoiA, Competence protein General function prediction only 77360738 Common - hypothetical protein PSHAa1798 9 None None None 77360955 Common cdsA phosphatidate cytidylyltransferase (CDP-diglyceride synthetase) (CDP-diglyceride pyrophosphorylase) (CDP-diacylglycerol synthase) (CDS) (CTP:phosphatidate cytidylyltransferase) (CDP-DAG synthase) (CDP-DG synthetase) PSHAa2031 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 77359734 Nonpathogen - hypothetical protein PSHAa0785 1 None None None 77361649 Common rraA ribonuclease activity regulator protein RraA PSHAa2734 68 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 77361039 Common - hypothetical protein PSHAa2116 82 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 77360190 Common - hypothetical protein PSHAa1247 6 None None None 77360022 Common - hypothetical protein ; membrane protein PSHAa1079 48 COG1289 COG1289, Predicted membrane protein Function unknown 77361831 Common tatA twin-arginine translocase subunit, sec-independent protein export PSHAa2929 53 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 77359296 Common - 5-carboxymethyl-2-hydroxymuconate delta isomerase PSHAa0329 20 COG3232 HpaF, 5-carboxymethyl-2-hydroxymuconate isomerase Amino acid transport and metabolism 77358998 Common - hypothetical protein PSHAa0016 9 None None None 77359745 Common fliJ flagellar protein PSHAa0796 19 COG2882 FliJ, Flagellar biosynthesis chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 77360114 Common - hypothetical protein PSHAa1171 167 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 77359009 Common - DNA topoisomerase PSHAa0027 120 COG0551 TopA, Zn-finger domain associated with topoisomerase type I DNA replication, recombination, and repair 77360634 Common - enzyme with RmlC-like domain PSHAa1693 64 COG2850 COG2850, Uncharacterized conserved protein Function unknown 77359085 Common - TonB-dependent receptor PSHAa0108 111 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 77359309 Common purD phosphoribosylglycinamide synthetase PSHAa0343 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 77361413 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase PSHAa2498 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 77359686 Common pdxJ pyridoxal phosphate biosynthetic protein PdxJ PSHAa0735 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 77360355 Nonpathogen - hypothetical protein PSHAa1412 1 None None None 77359302 Common ampH beta-lactamase PSHAa0335 146 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 77361496 Nonpathogen - hypothetical protein PSHAa2581 2 None None None 77359874 Common - pilin biogenesis protein PSHAa0927 37 COG3419 PilY1, Tfp pilus assembly protein, tip-associated adhesin PilY1 Cell motility and secretion / Intracellular trafficking and secretion 77359464 Common - hypothetical protein PSHAa0506 10 None None None 77360483 Common - hypothetical protein PSHAa1542 8 None None None 77359318 Common rpsU 30S ribosomal protein S21 PSHAa0352 93 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 77360318 Common secF preprotein translocase subunit SecF PSHAa1375 201 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 77360013 Common - hypothetical protein PSHAa1070 9 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 77361622 Common uvrA DNA excision repair enzyme subunit, with UvrBC PSHAa2707 234 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 77360345 Common - transcriptional regulator, AsnC PSHAa1402 149 COG1522 Lrp, Transcriptional regulators Transcription 77361732 Common - ABC transporter permease protein PSHAa2828 167 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 77359190 Common rplA 50S ribosomal protein L1 PSHAa0219 247 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 77360177 Common - Major NAD(P)H-flavin oxidoreductase PSHAa1234 83 COG0778 NfnB, Nitroreductase Energy production and conversion 77361688 Common dgkA diacylglycerol kinase (DAGK) PSHAa2773 48 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 77360950 Common lpxD UDP-3-O-(3-hydroxymyristoyl)-glucosamine N-acyltransferase PSHAa2026 169 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 77360701 Common ureF urease accessory protein UreF PSHAa1761 78 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 77361223 Common uppP undecaprenyl pyrophosphate phosphatase PSHAa2300 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 77359265 Common - hypothetical protein PSHAa0298 86 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 77360142 Nonpathogen - hypothetical protein PSHAa1199 1 None None None 77360195 Common - Sodium-dependent transporter PSHAa1252 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 77360560 Common etfdH Electron transfer flavoprotein-ubiquinone oxidoreductase(ETF-QO) (ETF-ubiquinone oxidoreductase) (ETF dehydrogenase) (Electron-transferring-flavoprotein dehydrogenase) PSHAa1619 107 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 77361015 Common hsdR type I restriction-modification system endonuclease; DEAD/DEAH box helicase motif PSHAa2091 129 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 77360333 Common lolE lipoprotein releasing system transmembrane protein PSHAa1390 158 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 77360052 Common - multi antimicrobial extrusion protein MatE/Na+-driven multidrug efflux pump PSHAa1109 149 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 77361040 Common tyrP tyrosine-specific transport protein (HAAAP) PSHAa2117 32 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 77361192 Common - hypothetical protein PSHAa2269 20 None None None 77361428 Common mraZ hypothetical protein PSHAa2513 143 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 77359411 Nonpathogen - hypothetical protein PSHAa0446 2 None None None 77359911 Common - ATPase protein PSHAa0965 180 COG0714 COG0714, MoxR-like ATPases General function prediction only 77361377 Common mdtJ multidrug transport protein (SmR superfamily) PSHAa2461 71 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 77361280 Common xseB exonuclease VII small subunit PSHAa2364 107 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 77360298 Common - glycosidase PSHAa1355 97 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 77361052 Common hdhA short chain dehydrogenase PSHAa2129 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77359922 Common - amino acid dehydrogenase with NAD(P)-binding domain and ferridoxin-like domain PSHAa0976 95 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 77360440 Common - Transglutaminase protein PSHAa1497 88 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 77360569 Common - Glutamate carboxypeptidase II PSHAa1628 48 COG2234 Iap, Predicted aminopeptidases General function prediction only 77360160 Nonpathogen - hypothetical protein PSHAa1217 1 None None None 77359659 Common - hypothetical protein PSHAa0707 10 None None None 77361883 Common - cold-shock RNAse R PSHAa2981 192 COG0557 VacB, Exoribonuclease R Transcription 77361718 Common rplR 50S ribosomal subunit protein L18 PSHAa2814 208 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 77359197 Common fusA elongation factor G PSHAa0226 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 77359641 Common - membrane protein; member of the DedA of proteins PSHAa0689 81 COG1238 COG1238, Predicted membrane protein Function unknown 77359801 Common - hypothetical protein PSHAa0852 4 None None None 77360058 Common - hypothetical protein PSHAa1115 41 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 77359808 Common - sodium-dependent transporter PSHAa0859 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 77359187 Common secE preprotein translocase subunit SecE PSHAa0216 66 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 77361207 Nonpathogen - hypothetical protein PSHAa2284 1 None None None 77361711 Common rpsD 30S ribosomal protein S4 PSHAa2807 235 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 77361211 Common argG argininosuccinate synthase PSHAa2288 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 77361894 Common - hypothetical protein PSHAa2993 76 COG3177 COG3177, Uncharacterized conserved protein Function unknown 77361214 Common argC N-acetyl-gamma-glutamyl-phosphate reductase PSHAa2291 214 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 77360447 Common - hypothetical protein PSHAa1506 5 None None None 77360729 Common - glycosyl transferase, 2 PSHAa1789 130 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 77359650 Common acs acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme) PSHAa0698 212 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 77359945 Common truB tRNA pseudouridine 5S synthase PSHAa0999 244 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 77359636 Common ispD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (4-diphosphocytidyl-2C-methyl-D-erythritol synthase) PSHAa0684 195 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 77361780 Common - hypothetical protein PSHAa2877 18 None None None 77359862 Common rpsT 30S ribosomal subunit protein S20 PSHAa0914 211 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 77360018 Common speA arginine decarboxylase PSHAa1075 153 COG1166 SpeA, Arginine decarboxylase (spermidine biosynthesis) Amino acid transport and metabolism 77360066 Common gcvR transcriptional repressor for cleavage of glycine PSHAa1123 34 COG2716 GcvR, Glycine cleavage system regulatory protein Amino acid transport and metabolism 77361814 Common - pantothenate kinase PSHAa2912 130 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 77360497 Common - hypothetical protein; could be an antifreeze protein PSHAa1556 16 COG4733 COG4733, Phage-related protein, tail component Function unknown 77361912 Common parB partitioning protein B PSHAa3016 183 COG1475 Spo0J, Predicted transcriptional regulators Transcription 77361361 Common ybdG hypothetical protein PSHAa2445 60 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 77361651 Common - hypothetical protein PSHAa2736 154 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 77359902 Common aspC aromatic amino acid aminotransferase PSHAa0956 71 COG1448 TyrB, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 77359513 Common - outer membrane transport protein PSHAa0558 129 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 77359772 Common ccmB heme exporter protein B, ABC superfamily (Cytochrome c-type biogenesis protein ccmB) PSHAa0823 89 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 77360537 Nonpathogen - hypothetical protein PSHAa1596 1 None None None 77360719 Common - Capsular polysaccharide biosynthesis, capC PSHAa1779 40 COG4464 CapC, Capsular polysaccharide biosynthesis protein Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 77360485 Common - hypothetical protein PSHAa1544 16 COG5005 COG5005, Mu-like prophage protein gpG General function prediction only 77359893 Common rplS 50S ribosomal protein L19 PSHAa0947 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 77359620 Common - carbon-nitrogen ligase PSHAa0668 187 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 77360640 Common - oxidoreductase protein PSHAa1699 55 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 77360228 Common - hypothetical protein PSHAa1285 67 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 77360749 Common fabD malonyl-CoA-[acyl-carrier-protein] transacylase PSHAa1809 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 77359126 Common cysJ sulfite reductase subunit alpha PSHAa0154 107 COG0369 CysJ, Sulfite reductase, alpha subunit (flavoprotein) Inorganic ion transport and metabolism 77360822 Common - hypothetical protein PSHAa1884 6 None None None 77359282 Common - transcriptional regulator PSHAa0315 177 COG0583 LysR, Transcriptional regulator Transcription 77360203 Common - permease PSHAa1260 30 COG3329 COG3329, Predicted permease General function prediction only 77360406 Common - hypothetical protein PSHAa1463 3 None None None 77361536 Common - Sensory box sensor histidine kinase/response regulator PSHAa2621 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77360966 Common phhB pterin-4-alpha-carbinolamine dehydratase PSHAa2042 85 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 77360309 Common edd phosphogluconate dehydratase PSHAa1366 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 77359225 Common rnk regulator of nucleoside diphosphate kinase PSHAa0258 58 COG0782 GreA, Transcription elongation factor Transcription 77361074 Common - short chain dehydrogenase PSHAa2151 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77360881 Common - hypothetical protein PSHAa1949 15 None None None 77360428 Common - Serine/threonine protein kinase PSHAa1485 11 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 77360396 Common - Transcriptional regulator PSHAa1453 53 COG0789 SoxR, Predicted transcriptional regulators Transcription 77361875 Common - secreted TonB-dependent receptor PSHAa2973 102 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 77360605 Common - hypothetical protein PSHAa1664 5 None None None 77361436 Common - methyltransferase PSHAa2521 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 77361110 Common - hypothetical protein PSHAa2187 51 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 77360469 Common - DNA binding protein PSHAa1528 14 COG1396 HipB, Predicted transcriptional regulators Transcription 77359535 Nonpathogen - hypothetical protein ; membrane protein PSHAa0580 4 None None None 77359990 Common - hypothetical protein PSHAa1044 200 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 77359358 Common aceF pyruvate dehydrogenase dihydrolipoyltransacetylase subunit PSHAa0392 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 77359750 Common fliO flagellar protein PSHAa0801 10 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 77361151 Common cyoD cytochrome o ubiquinol oxidase protein (Ubiquinol oxidase chain D) PSHAa2228 58 COG3125 CyoD, Heme/copper-type cytochrome/quinol oxidase, subunit 4 Energy production and conversion 77359245 Nonpathogen - hypothetical protein PSHAa0278 1 None None None 77361657 Common pctC chemotactic transducer PctC PSHAa2742 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77361725 Common asmA AsmA protein PSHAa2821 60 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 77360589 Common sdhB succinate dehydrogenase iron-sulfur subunit PSHAa1648 189 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 77359416 Common - ABC transporter PSHAa0451 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 77359581 Common - two-component system response regulator PSHAa0628 213 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77359792 Common - hypothetical protein PSHAa0843 63 COG2914 COG2914, Uncharacterized protein conserved in bacteria Function unknown 77360857 Common metC cystathionine beta-lyase, PLP-dependent (beta-cystathionase) PSHAa1925 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 77359797 Common - methyl-accepting chemotaxis protein PSHAa0848 155 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77359614 Common - hypothetical protein PSHAa0662 7 None None None 77359239 Common hflX protease GTPase subunit PSHAa0272 225 COG2262 HflX, GTPases General function prediction only 77359408 Common - RNAse PSHAa0443 122 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 77359067 Common xerC site-specific recombinase PSHAa0090 228 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 77360993 Common - hypothetical protein ; inner membrane protein PSHAa2069 24 None None None 77359016 Common - hypothetical protein PSHAa0038 4 None None None 77360714 Common prpC methylcitrate synthase PSHAa1774 194 COG0372 GltA, Citrate synthase Energy production and conversion 77360905 Common - Peptidyl-prolyl cis-trans isomerase (PPIase) PSHAa1981 127 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 77361100 Common - DNA ligase PSHAa2177 29 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 77360982 Common ppiD peptidyl-prolyl cis-trans isomerase D (PPIase D) (Rotamase D) PSHAa2058 158 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 77359319 Common - enzyme with N-6 Adenine-specific DNA methylase domain PSHAa0353 208 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 77360099 Nonpathogen - hypothetical protein PSHAa1156 1 None None None 77359572 Nonpathogen - hypothetical protein PSHAa0619 1 None None None 77359588 Common gltX glutamyl-tRNA synthetase PSHAa0635 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 77361000 Common - hypothetical protein ; membrane protein PSHAa2076 46 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 77360247 Nonpathogen - hypothetical protein PSHAa1304 1 None None None 77360367 Common cmk cytidine monophosphate (CMP) kinase; belong to the ubiquitous class of nucleotide kinase PSHAa1424 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 77360742 Common holB DNA polymerase III subunit delta prime PSHAa1802 213 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 77361587 Common iscR transcriptional repressor of the iscRSUA operon, involved in assembly of Fe-S clusters PSHAa2672 176 COG1959 COG1959, Predicted transcriptional regulator Transcription 77361058 Common - metallo-dependent enzymatic protein PSHAa2135 82 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 77361200 Common yajQ nucleotide-binding protein PSHAa2277 107 COG1666 COG1666, Uncharacterized protein conserved in bacteria Function unknown 77361632 Common pilP Type IV pilus biogenesis protein PilP PSHAa2717 37 COG3168 PilP, Tfp pilus assembly protein PilP Cell motility and secretion / Intracellular trafficking and secretion 77360753 Common - Maf/Ham1 domain PSHAa1813 190 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 77359328 Common - hypothetical protein PSHAa0362 51 None None None 77360852 Common fadE acyl-CoA dehydrogenase PSHAa1920 151 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77361674 Common elbB isoprenoid biosynthesis protein with amidotransferase-like domain PSHAa2759 38 COG3155 ElbB, Uncharacterized protein involved in an early stage of isoprenoid biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 77360863 Common - hypothetical protein PSHAa1931 15 None None None 77361325 Common - permease PSHAa2409 77 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 77359057 Common - hydrolase PSHAa0080 26 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 77361903 Common atpC membrane-bound ATP synthase, F1 sector, epsilon-subunit PSHAa3007 174 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 77359689 Common rumA 23S rRNA (uracil-5)-methyltransferase, responsible for modification at position U1939, SAM-dependent PSHAa0738 198 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 77360453 Nonpathogen - hypothetical protein PSHAa1512 1 None None None 77361500 Common parC DNA topoisomerase IV subunit A PSHAa2585 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 77360778 Common - hypothetical protein PSHAa1838 7 None None None 77361639 Common metJ transcriptional repressor protein MetJ PSHAa2724 23 COG3060 MetJ, Transcriptional regulator of met regulon Transcription / Amino acid transport and metabolism 77361583 Common hscB co-chaperone HscB PSHAa2668 56 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 77359509 Common yggH tRNA (m7G46) methyltransferase, SAM-dependent PSHAa0553 178 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 77359916 Nonpathogen - hypothetical protein PSHAa0970 1 None None None 77359724 Common flgG flagellar basal body rod protein FlgG PSHAa0774 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 77359094 Common uvrD DNA-dependent helicase II PSHAa0122 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 77359676 Common nadB L-aspartate oxidase PSHAa0725 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 77360342 Common rplT 50S ribosomal protein L20 PSHAa1399 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 77360971 Common pspC transcriptional activator of the psp operon with PspB, phage shock protein PSHAa2047 36 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 77361367 Common - hypothetical protein PSHAa2451 18 COG3615 TehB, Uncharacterized protein/domain, possibly involved in tellurite resistance Inorganic ion transport and metabolism 77361554 Common rfaH transcriptional activator RfaH PSHAa2639 45 COG0250 NusG, Transcription antiterminator Transcription 77360943 Common cydB cytochrome d terminal oxidase, polypeptide subunit II PSHAa2019 152 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 77361836 Common - GGDEF domain protein PSHAa2934 179 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 77360256 Common - protein with phospholipase D/nuclease domain PSHAa1313 139 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 77361509 Common - hypothetical protein PSHAa2594 2 None None None 77359500 Common - peptidase, M23/M37 PSHAa0544 188 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 77359206 Common gspG general secretion pathway protein G PSHAa0235 76 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 77359657 Common - hypothetical protein PSHAa0705 12 None None None 77361117 Nonpathogen - calcium-binding EF-hand domain PSHAa2194 1 None None None 77360720 Common - Exopolysaccharide biosynthesis protein PSHAa1780 161 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 77359950 Common - putative monovalent cation/H+ antiporter subunit A PSHAa1004 209 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 77359777 Common ccmG thiol:disulfide interchange protein dsbE (cytochrome c biogenesis protein ccmG) PSHAa0828 117 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 77360315 Common - ABC transporter ATP-binding protein PSHAa1372 249 COG5265 ATM1, ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components Posttranslational modification, protein turnover, chaperones 77359973 Common - hypothetical protein PSHAa1027 201 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 77359487 Common - hypothetical protein PSHAa0530 3 COG5473 COG5473, Predicted integral membrane protein Function unknown 77359960 Nonpathogen - secreted calmodulin-like protein PSHAa1014 1 None None None 77360133 Common ExbD2 TonB system transport protein ExbD2 PSHAa1190 74 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 77359842 Common tesD hydrolase acting on oxygenated substrates (epoxide hydrolase) PSHAa0893 169 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77359983 Nonpathogen - hypothetical protein PSHAa1037 4 None None None 77361656 Common - enzyme with NAD(P)-binding domain PSHAa2741 35 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 77359739 Common flaM Sigma-54 dependent response regulator; regulation of polar flagellae expression PSHAa0790 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77361316 Common - hypothetical protein PSHAa2400 16 None None None 77360518 Common - ribosomal-protein-alanine acetyltransferase PSHAa1577 24 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 77359227 Common groS chaperonin PSHAa0260 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 77359293 Common - hypothetical protein PSHAa0326 38 COG0401 COG0401, Uncharacterized homolog of Blt101 Function unknown 77361353 Common - hypothetical protein PSHAa2437 1 None None None 77359826 Common - steroid degradation protein PSHAa0877 47 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77359259 Common slyDB peptidyl-prolyl cis-trans isomerase PSHAa0292 129 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 77361898 Common cobU adenosylcobalamin biosynthesis protein PSHAa2997 129 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 77360551 Common bioA adenosylmethionine-8-amino-7-oxononanoate aminotransferase (7,8-diaminopelargonic acid synthetase), PLP-dependent PSHAa1610 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 77361458 Common - transport protein (ABC superfamily, membrane) PSHAa2543 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 77361309 Common - fumarylacetoacetate hydrolase protein PSHAa2393 178 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 77359478 Common - hypothetical protein PSHAa0521 51 COG3876 COG3876, Uncharacterized protein conserved in bacteria Function unknown 77359308 Common - transposase PSHAa0341 80 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 77361392 Common - bacterial regulatory protein PSHAa2477 192 COG0583 LysR, Transcriptional regulator Transcription 77359932 Common - hypothetical protein PSHAa0986 31 COG3101 COG3101, Uncharacterized protein conserved in bacteria Function unknown 77360675 Common mdtK multidrug transport protein (MATE) PSHAa1735 163 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 77359201 Common hslR heat shock protein 15 PSHAa0230 94 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 77360687 Common - pectin degradation protein (Sugar phosphate isomerase) PSHAa1747 39 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 77360100 Common - response regulator PSHAa1157 205 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 77359060 Common - hypothetical protein PSHAa0083 25 None None None 77360045 Common rsxD Electron transport complex protein rnfD. PSHAa1102 77 COG4658 RnfD, Predicted NADH:ubiquinone oxidoreductase, subunit RnfD Energy production and conversion 77359179 Common cysQ 3',5' adenosine diphosphate 3' phosphatase PSHAa0208 175 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 77359170 Common speD S-adenosylmethionine decarboxylase PSHAa0199 30 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 77360326 Common - transporter PSHAa1383 27 COG1285 SapB, Uncharacterized membrane protein Function unknown 77361525 Common - lipoprotein PSHAa2610 44 COG4805 COG4805, Uncharacterized protein conserved in bacteria Function unknown 77361713 Common rpsM 30S ribosomal protein S13 PSHAa2809 240 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 77361852 Common rbgA ribosomal biogenesis GTPase PSHAa2950 102 COG1161 COG1161, Predicted GTPases General function prediction only 77361342 Common fadL Long-chain fatty acid transport protein precursor (Outer membrane fadL protein) PSHAa2426 71 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 77361007 Common - hypothetical protein ; membrane protein PSHAa2083 23 COG0730 COG0730, Predicted permeases General function prediction only 77360233 Common trpCF bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase PSHAa1290 220 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 77361488 Nonpathogen - hypothetical protein PSHAa2573 2 None None None 77360286 Common - short chain dehydrogenase PSHAa1343 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77359153 Common - hypothetical protein PSHAa0182 110 COG0397 COG0397, Uncharacterized conserved protein Function unknown 77359045 Common - serine endoprotease PSHAa0068 47 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 77361296 Common - response regulator with Chemotaxis-specific methylesterase domain PSHAa2380 197 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77359114 Common plsB glycerol-3-phosphate acyltransferase PSHAa0142 48 COG2937 PlsB, Glycerol-3-phosphate O-acyltransferase Lipid metabolism 77358990 Nonpathogen - hypothetical protein PSHAa0008 2 None None None 77359701 Common galU UTP-glucose-1-phosphate uridylyltransferase PSHAa0750 231 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 77361108 Common - amidohydrolase PSHAa2185 52 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 77359939 Common ibpA small heat shock protein PSHAa0993 64 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 77360275 Common - enzyme with thioredoxin-like domain PSHAa1332 109 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 77359144 Common - hypothetical protein PSHAa0173 33 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 77361256 Common tadA tRNA-specific adenosine deaminase PSHAa2333 219 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 77360264 Common - hypothetical protein PSHAa1321 32 COG3148 COG3148, Uncharacterized conserved protein Function unknown 77360338 Common - hypothetical protein PSHAa1395 11 None None None 77361691 Common cusS sensor transduction kinase (copper resistance) PSHAa2776 201 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77361776 Common lexA transcriptional repressor for SOS response PSHAa2873 171 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 77359557 Common folK 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase PSHAa0603 202 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 77359076 Common hemDX uroporphyrinogen-III synthase PSHAa0099 49 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 77360050 Nonpathogen - hypothetical protein PSHAa1107 1 None None None 77361234 Common - chorismate pyruvate lyase UbiC PSHAa2311 43 COG3161 UbiC, 4-hydroxybenzoate synthetase (chorismate lyase) Coenzyme metabolism 77361182 Common - two-component response regulator protein with GGDEF domain PSHAa2259 217 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 77360708 Common - sodium/hexose cotransport protein PSHAa1768 154 COG4146 COG4146, Predicted symporter General function prediction only 77361085 Common bcsA cellulose synthase catalytic subunit PSHAa2162 126 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 77360699 Common ureC urease subunit alpha PSHAa1759 96 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 77361217 Common - hypothetical protein PSHAa2294 157 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 77360293 Common - hypothetical protein PSHAa1350 55 COG2862 COG2862, Predicted membrane protein Function unknown 77359522 Common - sterol desaturase protein PSHAa0567 75 COG3000 ERG3, Sterol desaturase Lipid metabolism 77360820 Common - hypothetical protein PSHAa1882 85 COG0393 COG0393, Uncharacterized conserved protein Function unknown 77359851 Common - enoyl-CoA hydratase PSHAa0903 180 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 77361068 Common hsdA 3 alpha-hydroxysteroid dehydrogenase/carbonyl reductase PSHAa2145 234 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77361763 Common - predicted gluconate transport-associated protein PSHAa2860 59 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 77361123 Common - deoxyribodipyrimidine photolyase PSHAa2200 131 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 77361042 Common - TonB-dependent receptor PSHAa2119 114 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 77360135 Common - TPR domain protein (tetratricopeptide repeat) PSHAa1192 23 COG1747 COG1747, Uncharacterized N-terminal domain of the transcription elongation factor GreA Function unknown 77359090 Common trxA thioredoxin PSHAa0113 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 77360508 Common - rhomboid protein PSHAa1567 17 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 77360543 Common - hypothetical protein PSHAa1602 6 None None None 77359716 Common cheV chemotaxis protein PSHAa0766 185 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 77359812 Common - outer membrane protein PSHAa0863 19 COG3713 OmpV, Outer membrane protein V Cell envelope biogenesis, outer membrane 77359858 Common - allophanate hydrolase PSHAa0910 219 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 77360706 Common - hypothetical protein PSHAa1766 3 None None None 77360352 Common sppA protease IV, a signal peptide peptidase PSHAa1409 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 77359236 Common mutL methyl-directed mismatch repair protein PSHAa0269 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 77359690 Common relA (p)ppGpp synthetase I (GTP pyrophosphokinase) PSHAa0739 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 77360063 Common - hypothetical protein PSHAa1120 27 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 77360218 Common - Bax protein PSHAa1275 30 COG2992 Bax, Uncharacterized FlgJ-related protein General function prediction only 162139926 Common nrdB ribonucleotide-diphosphate reductase subunit beta PSHAa1417 155 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 77361662 Common pmbA enzyme for maturation of Microcin B17 and degradation of CcdA PSHAa2747 155 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 77361244 Nonpathogen - hypothetical protein PSHAa2321 3 None None None 77360717 Common yebU rRNA (cytosine-C(5)-)-methyltransferase RsmF PSHAa1777 207 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 77361548 Common surA peptidyl-prolyl cis-trans isomerase (PPIase) PSHAa2633 162 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 77359341 Common cpxR transcriptional regulator PSHAa0375 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77360112 Common - GGDEF protein PSHAa1169 183 COG3292 COG3292, Predicted periplasmic ligand-binding sensor domain Signal transduction mechanisms 77361645 Common hslV ATP-dependent protease peptidase subunit PSHAa2730 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 77360892 Common mltD lytic murein transglycosylase C, membrane-bound PSHAa1967 135 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 77360437 Common - peptidase, M23/M37 PSHAa1494 189 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 77361418 Common murC UDP-N-acetyl-muramate:alanine ligase, L-alanine adding enzyme PSHAa2503 210 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 77361334 Nonpathogen - hypothetical protein PSHAa2418 1 None None None 77359668 Common - enoyl-CoA hydratase PSHAa0717 161 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 77359878 Common glnB regulatory protein (P-II) for nitrogen assimilation by glutamine synthetase (ATase) PSHAa0931 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 77361805 Common slyX hypothetical protein PSHAa2903 7 COG2900 SlyX, Uncharacterized protein conserved in bacteria Function unknown 77361170 Common - peptidylprolyl isomerase PSHAa2247 136 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 77359811 Common - hypothetical protein ; signal peptide PSHAa0862 4 None None None 77359256 Common - hypothetical protein PSHAa0289 30 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 77361704 Common - hypothetical protein PSHAa2795 36 COG1315 COG1315, Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain DNA replication, recombination, and repair 77361856 Common dpsB DNA-binding DPS protein PSHAa2954 128 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 77359261 Common - hypothetical protein PSHAa0294 25 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 77361845 Common - succinyl-CoA transferase, alpha subunit PSHAa2943 97 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 77359601 Common guaB inositol-5-monophosphate dehydrogenase PSHAa0648 236 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 77360558 Common etfA electron transfer flavoprotein alpha-subunit (Alpha-ETF) (Electron transfer flavoprotein large subunit) (ETFLS) PSHAa1617 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 77359833 Common - hypothetical protein PSHAa0884 31 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 77361216 Common - cysteine sulfinic acid decarboxylase PSHAa2293 118 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 77361597 Common mreB Rod shape-determining protein PSHAa2682 234 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 77359250 Common - transport protein PSHAa0283 116 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77360888 Common dnaQ DNA polymerase III subunit epsilon PSHAa1963 183 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 77360526 Common - hypothetical protein PSHAa1585 18 None None None 77361541 Nonpathogen - hypothetical protein PSHAa2626 3 None None None 77360129 Nonpathogen - hypothetical protein PSHAa1186 1 None None None 77361165 Common - short-chain alcohol dehydrogenase protein PSHAa2242 25 COG3007 COG3007, Uncharacterized paraquat-inducible protein B Function unknown 77360619 Common prc carboxy-terminal protease PSHAa1678 182 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 77359347 Common pilC type IV pilus biogenesis protein C PSHAa0381 152 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 77359743 Common fliH flagellar assembly protein H PSHAa0794 70 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 77361475 Common - hypothetical protein PSHAa2560 2 None None None 77361466 Common rpoN sigma N (sigma 54) factor of RNA polymerase PSHAa2551 145 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 77359538 Common - hypothetical protein PSHAa0583 74 COG1238 COG1238, Predicted membrane protein Function unknown 77360368 Common rpsA 30S ribosomal protein S1 PSHAa1425 218 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 77359123 Common rplP 50S ribosomal protein L16 PSHAa0151 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 77359151 Common dapA dihydrodipicolinate synthase PSHAa0180 232 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 77360904 Common queF 7-cyano-7-deazaguanine reductase PSHAa1980 91 COG2904 COG2904, Uncharacterized protein conserved in bacteria Function unknown 77359597 Common - two-component response regulator with GGDEF domain PSHAa0644 180 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 77361299 Common - hypothetical protein PSHAa2383 13 None None None 77360661 Common aat leucyl/phenylalanyl-tRNA--protein transferase PSHAa1721 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 77359567 Common - conserved excreted enzyme of unknown function PSHAa0614 113 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 77359786 Common dsbB disulfide bond formation protein B (Disulfide oxidoreductase) PSHAa0837 56 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 77359661 Common - hypothetical protein PSHAa0709 16 COG3868 COG3868, Uncharacterized conserved protein Function unknown 77360819 Nonpathogen - hypothetical protein PSHAa1881 1 None None None 77360158 Common sodB iron superoxide dismutase PSHAa1215 207 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 77360373 Nonpathogen - hypothetical protein PSHAa1430 1 None None None 77360668 Common - amidohydrolase protein PSHAa1728 38 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 77359291 Common - hypothetical protein PSHAa0324 14 COG4758 COG4758, Predicted membrane protein Function unknown 77360683 Common fbaA fructose-bisphosphate aldolase PSHAa1743 174 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 77359421 Common - HAMP domain/GGDEF domain/EAL domain protein PSHAa0456 171 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 77359574 Nonpathogen - hypothetical protein PSHAa0621 1 None None None 77361199 Nonpathogen - hypothetical protein PSHAa2276 1 None None None 77360492 Common - phage-related minor tail protein PSHAa1551 34 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 77359934 Common - hypothetical protein PSHAa0988 17 None None None 77359052 Common nadE NAD synthetase PSHAa0075 136 COG0171 NadE, NAD synthase Coenzyme metabolism 77360295 Common - TonB-dependent receptor protein PSHAa1352 26 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 77361686 Common ilvG acetolactate synthase 2 catalytic subunit PSHAa2771 223 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 77359652 Common - p-aminobenzoyl-glutamate transport protein (AbgT) PSHAa0700 41 COG2978 AbgT, Putative p-aminobenzoyl-glutamate transporter Coenzyme metabolism 77360071 Common - hypothetical protein PSHAa1128 10 None None None 77360044 Common rsxG Electron transport complex protein rnfG. PSHAa1101 60 COG4659 RnfG, Predicted NADH:ubiquinone oxidoreductase, subunit RnfG Energy production and conversion 77361270 Nonpathogen - hypothetical protein PSHAa2354 4 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77360082 Common pgi glucosephosphate isomerase PSHAa1139 194 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 77359462 Common - hypothetical protein PSHAa0504 18 COG5345 COG5345, Uncharacterized protein conserved in bacteria Function unknown 77359473 Common dsbC disulfide bond isomerase, periplasmic; chaperone; activated by DsbD; homodimeric PSHAa0515 68 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 77360235 Common trpG Anthranilate synthase component II (Glutamine amido-transferase) PSHAa1292 232 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 77361374 Common - sulfate permease protein PSHAa2458 158 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 77359913 Common fadJ multifunctional fatty acid oxidation complex subunit alpha PSHAa0967 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 77360187 Common - hypothetical protein PSHAa1244 23 None None None 77359994 Common engD translation-associated GTPase PSHAa1051 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 77359646 Common recA RecA protein (Recombinase A) PSHAa0694 214 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 77361221 Common - aromatic acid decarboxylase PSHAa2298 152 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 77360825 Common - hypothetical protein PSHAa1887 4 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 77359268 Common - hypothetical protein PSHAa0301 5 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 77360335 Common gdhA glutamate dehydrogenase PSHAa1392 164 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 77359529 Common - alcohol dehydrogenase with dehydroquinate synthase-like domain PSHAa0574 168 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 77360798 Common recB exonuclease V, beta chain with recC and recD: 5' and 3' nuclease, ATPase, recombinase, helicase PSHAa1858 196 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 77360726 Common - glycosyl transferase, WecB/TagA/CpsF PSHAa1786 84 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 77360164 Common - hypothetical protein PSHAa1221 141 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 77359312 Common fis DNA-binding protein PSHAa0346 97 COG2901 Fis, Factor for inversion stimulation Fis, transcriptional activator Transcription / DNA replication, recombination, and repair 77359633 Common - hypothetical protein PSHAa0681 6 None None None 77361047 Common - hypothetical protein PSHAa2124 8 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 77360212 Common - fatty acid desaturase PSHAa1269 31 COG3239 DesA, Fatty acid desaturase Lipid metabolism 77359634 Common - hypothetical protein PSHAa0682 3 None None None 77360175 Common - hypothetical protein PSHAa1232 29 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 77360039 Common uvrD DNA helicase II. PSHAa1096 49 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 77359376 Common - transposase PSHAa0410 65 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 77361893 Common - hypothetical protein PSHAa2992 15 COG3177 COG3177, Uncharacterized conserved protein Function unknown 77361793 Nonpathogen - hypothetical protein ; membrane protein PSHAa2890 1 None None None 77359267 Common - hypothetical protein PSHAa0300 99 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 77361194 Common - hypothetical protein PSHAa2271 8 None None None 77360445 Common - transcriptional regulator PSHAa1504 64 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 77359924 Common - L-lactate permease PSHAa0978 102 COG1620 LldP, L-lactate permease Energy production and conversion 77361625 Common rpe D-ribulose-5-phosphate 3-epimerase PSHAa2710 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 77360804 Common - hypothetical protein PSHAa1864 15 None None None 77360460 Nonpathogen - hypothetical protein PSHAa1519 1 None None None 77359819 Common ftsH cell division protease PSHAa0870 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 77359007 Common smf hypothetical protein PSHAa0025 211 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 77360791 Common uspE universal stress protein UspE PSHAa1851 64 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 77361863 Common - membrane-bound protein PSHAa2961 36 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 77360312 Common - hypothetical protein PSHAa1369 34 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 77359195 Common rpsL 30S ribosomal protein S12 PSHAa0224 242 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 77360475 Nonpathogen - hypothetical protein PSHAa1534 1 None None None 77360957 Common frr ribosome releasing factor PSHAa2033 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 77359455 Common - CheC-like protein PSHAa0492 26 COG1406 COG1406, Predicted inhibitor of MCP methylation, homolog of CheC Cell motility and secretion 77360138 Common dusC tRNA-dihydrouridine synthase C PSHAa1195 206 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 77360105 Common cysB transcriptional regulator CysB PSHAa1162 181 COG0583 LysR, Transcriptional regulator Transcription 77361363 Common nemA N-ethylmaleimide reductase, FMN-linked PSHAa2447 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 77360353 Common fadH 2,4-dienoyl-CoA reductase (NADPH) PSHAa1410 190 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 77361677 Common rep Rep helicase, a single-stranded DNA-dependent ATPase PSHAa2762 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 77360173 Common greA transcription elongation factor greA PSHAa1230 203 COG0782 GreA, Transcription elongation factor Transcription 77360419 Common - hypothetical protein PSHAa1476 61 COG1262 COG1262, Uncharacterized conserved protein Function unknown 77359087 Common - DnaJ-class molecular chaperone PSHAa0110 10 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 77361563 Common - oxidoreductase with FAD/NAD(P)-binding domain PSHAa2648 136 COG2081 COG2081, Predicted flavoproteins General function prediction only 77361314 Common - sigma-54 interacting response regulator protein PSHAa2398 182 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77359164 Common - hypothetical protein PSHAa0193 4 None None None 77360430 Common - hypothetical protein PSHAa1487 35 COG4628 COG4628, Uncharacterized conserved protein Function unknown 77360029 Nonpathogen - hypothetical protein ; membrane protein PSHAa1086 1 None None None 77359957 Common copAB P-type ATPase, copper transporting, phophatase-like domain PSHAa1011 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 77360877 Common - methyltransferase with S-adenosyl-L-methionine-dependent methyltransferase domain PSHAa1945 54 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 77361785 Common - hypothetical protein ; membrane protein PSHAa2882 2 None None None 77361398 Common - glycerophosphodiester phosphodiesterase PSHAa2483 121 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 77359590 Nonpathogen - hypothetical protein PSHAa0637 1 None None None 77359770 Common - hypothetical protein PSHAa0821 2 None None None 77361512 Nonpathogen - hypothetical protein PSHAa2597 1 None None None 77359763 Common - Chemotaxis motA protein PSHAa0814 109 COG1291 MotA, Flagellar motor component Cell motility and secretion 77360089 Common - hypothetical protein PSHAa1146 5 None None None 77360736 Nonpathogen - hypothetical protein ; signal peptide PSHAa1796 1 None None None 77360418 Common - hypothetical protein PSHAa1475 50 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 77360423 Common - Cytochrome b561 PSHAa1480 83 COG3038 CybB, Cytochrome B561 Energy production and conversion 77358983 Common dnaA DNA replication initiator PSHAa0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 77361391 Common - hypothetical protein ; enzyme PSHAa2476 14 None None None 77361220 Common - ATP-binding component of ABC transport system PSHAa2297 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 77361519 Common - enzyme with PLP-binding domain PSHAa2604 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 77359684 Common era GTP-binding protein era PSHAa0733 232 COG1159 Era, GTPase General function prediction only 77361571 Common rplU 50S ribosomal subunit protein L21 PSHAa2656 215 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 77360849 Common - sodium-glutamate symporter PSHAa1917 150 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 77360458 Nonpathogen - hypothetical protein PSHAa1517 1 None None None 77360182 Common - transport protein PSHAa1239 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 77360907 Common - outer membrane protein PSHAa1983 128 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 77359883 Common - aerotaxis sensor receptor (Aer-like) PSHAa0936 162 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77360768 Common - cytochrome c (partial) PSHAa1828 35 COG3258 COG3258, Cytochrome c Energy production and conversion 77361823 Common - C-N hydrolase PSHAa2921 161 COG0388 COG0388, Predicted amidohydrolase General function prediction only 77359287 Common yajC preprotein translocase subunit YajC PSHAa0320 171 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 77359043 Common - cytochrome c' PSHAa0066 25 COG3909 COG3909, Cytochrome c556 Energy production and conversion 77361608 Common mshN Mannose-sensitive agglutinin (MSHA) biogenesis protein MshN (pilus type IV) PSHAa2693 15 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 77361442 Common sspA stringent starvation protein A PSHAa2527 101 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 77359324 Common - hypothetical protein PSHAa0358 65 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 77360034 Common gloA glyoxalase I, nickel isomerase (Lactoylglutathione lyase) PSHAa1091 132 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 77361679 Common yraR NADH dehydrogenase with NAD(P)-binding domain PSHAa2764 51 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 77361009 Nonpathogen - hypothetical protein PSHAa2085 1 None None None 77360786 Common - hypothetical protein PSHAa1846 21 COG3198 COG3198, Uncharacterized protein conserved in bacteria Function unknown 77360840 Common ihfA integration host factor (IHF), alpha subunit, DNA-bending protein, DNA replication PSHAa1902 211 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 77360587 Common sucB dihydrolipoyltranssuccinate transferase, component of the 2-oxoglutarate dehydrogenase complex PSHAa1646 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 77361706 Common asnC DNA-binding transcriptional regulator AsnC PSHAa2797 155 COG1522 Lrp, Transcriptional regulators Transcription 77360520 Common - hypothetical protein PSHAa1579 13 None None None 77361727 Nonpathogen - hypothetical protein PSHAa2823 1 None None None 77360444 Common - hypothetical protein PSHAa1502 3 None None None 77360855 Common - ABC transporter ATP-binding protein PSHAa1923 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 77359014 Common - hypothetical protein PSHAa0032 9 None None None 77360607 Common - hypothetical protein PSHAa1666 3 None None None 77359439 Common efp elongation factor P (EF-P) PSHAa0474 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 77359432 Common rsuA 16S rRNA pseudouridylate 516 synthase PSHAa0467 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 77359545 Common - extracellular solute-binding protein PSHAa0590 48 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 77360451 Common - hypothetical protein PSHAa1510 10 None None None 77361627 Common dam DNA adenine methylase PSHAa2712 95 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 77359418 Common - hypothetical protein PSHAa0453 49 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 77360712 Common - hypothetical protein PSHAa1772 55 COG2828 COG2828, Uncharacterized protein conserved in bacteria Function unknown 77361850 Common - transcriptional regulator PSHAa2948 181 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 77361787 Nonpathogen - hypothetical protein PSHAa2884 1 None None None 77360249 Common - transcriptional regulator PSHAa1306 96 COG0583 LysR, Transcriptional regulator Transcription 77359955 Common - putative monovalent cation/H+ antiporter subunit G PSHAa1009 51 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 77360060 Common queC queC protein PSHAa1117 155 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 77361637 Common metL bifunctional aspartate kinase II/homoserine dehydrogenase II PSHAa2722 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 77359693 Common eno phosphopyruvate hydratase PSHAa0742 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 77361355 Common rplI 50S ribosomal protein L9 PSHAa2439 213 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 77360252 Common - hypothetical protein PSHAa1309 5 None None None 77360512 Common - hypothetical protein PSHAa1571 20 None None None 77359326 Common gor glutathione reductase PSHAa0360 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 77360329 Common adhC alcohol dehydrogenase class III PSHAa1386 208 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 77361630 Common aroK shikimate kinase I PSHAa2715 194 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 77361102 Nonpathogen - hypothetical protein PSHAa2179 1 None None None 77361157 Common - hypothetical protein PSHAa2234 3 COG2991 COG2991, Uncharacterized protein conserved in bacteria Function unknown 77359907 Common - hypothetical protein PSHAa0961 51 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 77359054 Common - sensor protein PSHAa0077 223 COG3452 COG3452, Predicted periplasmic ligand-binding sensor domain Signal transduction mechanisms 77361585 Common iscU scaffold protein PSHAa2670 148 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 77360365 Common serC phosphoserine aminotransferase PSHAa1422 112 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 77361267 Common - transcriptional regulator PSHAa2351 14 None None None 77361589 Nonpathogen - hypothetical protein PSHAa2674 1 None None None 77359363 Common - hypothetical protein PSHAa0397 33 COG3137 COG3137, Putative salt-induced outer membrane protein Cell envelope biogenesis, outer membrane 77361327 Common - hypothetical protein PSHAa2411 64 COG3791 COG3791, Uncharacterized conserved protein Function unknown 77361002 Common asd Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH) PSHAa2078 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 77359446 Common thiS ThiS protein PSHAa0482 20 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 77360144 Common - DnaX, DNA polymerase III, gamma/tau subunits PSHAa1201 248 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 77361816 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase PSHAa2914 197 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 77360024 Common - SMC protein PSHAa1081 185 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 77360487 Nonpathogen - hypothetical protein PSHAa1546 1 None None None 77360244 Nonpathogen - hypothetical protein PSHAa1301 1 None None None 77360226 Common phoP response regulator in two-component regulatory system with PhoQ PSHAa1283 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77360494 Common - hypothetical protein PSHAa1553 3 None None None 77359616 Nonpathogen - hypothetical protein PSHAa0664 1 None None None 77360313 Common - hypothetical protein PSHAa1370 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 77361885 Common rhlE DEAD-box protein; ATP-dependent RNA helicase with P-loop hydrolase domain PSHAa2983 240 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 77360539 Nonpathogen - hypothetical protein PSHAa1598 1 None None None 77361914 Common gidB glucose-inhibited division protein B PSHAa3018 203 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 77361260 Nonpathogen - hypothetical protein PSHAa2343 1 None None None 77361251 Common - hypothetical protein PSHAa2328 26 None None None 77361463 Common - hypothetical protein PSHAa2548 24 COG3117 COG3117, Uncharacterized protein conserved in bacteria Function unknown 77360814 Common ruvA Holliday junction DNA helicase motor protein PSHAa1876 210 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 77360003 Common - transcriptional regulator PSHAa1060 31 COG3094 COG3094, Uncharacterized protein conserved in bacteria Function unknown 77361080 Common tyrR Transcriptional regulatory protein tyrR PSHAa2157 171 COG3283 TyrR, Transcriptional regulator of aromatic amino acids metabolism Transcription / Amino acid transport and metabolism 77359726 Common flgI flagellar basal body P-ring protein PSHAa0776 104 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 77359900 Common - response regulator PSHAa0954 223 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 77361248 Common kdtA 3-deoxy-D-manno-octulosonic-acid transferase (KDO transferase) PSHAa2325 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 77361750 Common speE spermidine synthase PSHAa2847 121 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 77361135 Common - hypothetical protein PSHAa2212 1 None None None 77359071 Nonpathogen - hypothetical protein PSHAa0094 1 COG5567 COG5567, Predicted small periplasmic lipoprotein Cell motility and secretion 77359895 Common tyrA bifunctional chorismate mutase/prephenate dehydrogenase PSHAa0949 130 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 77359395 Common - N-formylglutamate amidohydrolase PSHAa0429 58 COG3741 HutG, N-formylglutamate amidohydrolase Amino acid transport and metabolism 77359515 Common - multidrug resistance protein(AcrB/AcrD/AcrF) PSHAa0560 178 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 77361132 Common - hypothetical protein PSHAa2209 30 COG4446 COG4446, Uncharacterized protein conserved in bacteria Function unknown 77361164 Common nqrA Na(+)-translocating NADH-quinone reductase subunit A PSHAa2241 39 COG1726 NqrA, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA Energy production and conversion 77360284 Common - hypothetical protein PSHAa1341 146 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 77360590 Common sdhA succinate dehydrogenase flavoprotein subunit PSHAa1649 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 77360676 Common - hypothetical protein PSHAa1736 8 None None None 77359385 Common - RNA-directed DNA polymerase PSHAa0419 82 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 77359280 Common - hypothetical protein PSHAa0313 38 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 77359107 Common - metalloprotease PSHAa0135 27 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 77359867 Common fkpB FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) PSHAa0920 130 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 77360467 Nonpathogen - hypothetical protein PSHAa1526 1 None None None 77360011 Common cysZ putative sulfate transport protein CysZ PSHAa1068 44 COG2981 CysZ, Uncharacterized protein involved in cysteine biosynthesis Amino acid transport and metabolism 77359005 Common def N-terminal methionine peptide deformylase PSHAa0023 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 77360764 Common - ferric enterobactin receptor PSHAa1824 100 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 77359622 Common metK S-adenosylmethionine synthetase PSHAa0670 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 77359752 Common fliQ flagellar biosynthesis PSHAa0803 60 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 77359864 Common ribF riboflavin kinase / FMN adenylyltransferase PSHAa0917 211 COG0196 RibF, FAD synthase Coenzyme metabolism 77360302 Nonpathogen - hypothetical protein ; coiled-coil protein PSHAa1359 4 None None None 77361577 Common fbpB Iron(III) ABC transporter permease protein PSHAa2662 159 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 77360205 Nonpathogen - hypothetical protein PSHAa1262 1 None None None 77359314 Common prmA 50S ribosomal protein L11 methyltransferase PSHAa0348 189 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 77361507 Common tolC outer membrane channel protein PSHAa2592 143 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 77359824 Common - oxidoreductase, short-chain dehydrogenase/reductase PSHAa0875 232 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 77361185 Common - hypothetical protein PSHAa2262 34 COG3103 COG3103, SH3 domain protein Signal transduction mechanisms 77360408 Common - mini-circle transposase for IS117 PSHAa1465 32 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 77359583 Common - Inter-alpha-trypsin inhibitor domain protein PSHAa0630 42 COG2425 COG2425, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 77361574 Common argR arginine repressor PSHAa2659 75 COG1438 ArgR, Arginine repressor Transcription 77361468 Common ptsN PTS enzyme IIA PSHAa2553 135 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 77360531 Common - 6-oxohexanoate dehydrogenase, succinate-semialdehyde dehydrogenase (NADP+) PSHAa1590 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77360850 Common cysK O-acetylserine sulfhydrylase, PLP-dependent enzyme PSHAa1918 220 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 77361807 Common - ABC transporter ATP-binding protein PSHAa2905 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 77360239 Common - hypothetical protein PSHAa1296 141 COG1354 COG1354, Uncharacterized conserved protein Function unknown 77360279 Common - hypothetical protein PSHAa1336 23 COG3092 COG3092, Uncharacterized protein conserved in bacteria Function unknown 77360926 Common ygfH propionyl-CoA:succinate-CoA transferase PSHAa2002 97 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 77359491 Common csrA carbon storage regulator PSHAa0534 81 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 77359116 Common rplC 50S ribosomal subunit protein L3 PSHAa0144 236 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 77361340 Common holC DNA polymerase III subunit chi PSHAa2424 54 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 77360597 Common - Molybdenum cofactor biosynthesis protein MoeB, NAD(P)-binding PSHAa1656 220 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 77358992 Common fadA 3-ketoacyl-CoA thiolase PSHAa0010 187 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 77361294 Common thrB homoserine kinase PSHAa2378 128 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 77359413 Common - hypothetical protein PSHAa0448 28 None None None 77361300 Common - conserved protein of unknown function; membrane protein PSHAa2384 15 COG3453 COG3453, Uncharacterized protein conserved in bacteria Function unknown 77360324 Common - transcriptional regulator PSHAa1381 153 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 77359940 Common - hypothetical protein PSHAa0994 59 COG3046 COG3046, Uncharacterized protein related to deoxyribodipyrimidine photolyase General function prediction only 77359790 Common smpB SsrA-binding protein PSHAa0841 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 77359215 Common - hypothetical protein PSHAa0244 4 None None None 77361654 Common hutU urocanate hydratase PSHAa2739 97 COG2987 HutU, Urocanate hydratase Amino acid transport and metabolism 77360350 Common - 6-phosphogluconate dehydrogenase PSHAa1407 144 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 77361743 Common - export protein (LysE) PSHAa2839 63 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 77359947 Common pnp polynucleotide phosphorylase/polyadenylase PSHAa1001 242 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 77361072 Common - transcriptional regulator containing an Adenosine deaminase domain and an AraC-type DNA-binding HTH domain PSHAa2149 71 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77360473 Nonpathogen - hypothetical protein PSHAa1532 1 None None None 77360562 Common - TonB-dependent receptor protein with OmpA-like transmembrane domain PSHAa1621 22 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 77360625 Common - hypothetical protein PSHAa1684 39 COG1553 DsrE, Uncharacterized conserved protein involved in intracellular sulfur reduction Inorganic ion transport and metabolism 77359142 Common rbn ribonuclease BN PSHAa0171 162 COG1295 Rbn, Predicted membrane protein Function unknown 77359426 Nonpathogen - hypothetical protein PSHAa0461 1 None None None 77360262 Common dcd deoxycytidine triphosphate deaminase PSHAa1319 150 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 77360277 Nonpathogen - hypothetical protein PSHAa1334 1 COG3603 COG3603, Uncharacterized conserved protein Function unknown 77361258 Common - glutaminase PSHAa2335 72 COG2066 GlsA, Glutaminase Amino acid transport and metabolism 77361021 Nonpathogen - hypothetical protein PSHAa2097 1 None None None 77359135 Common glnG two-compnent response regulator PSHAa0163 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77360580 Common fldA flavodoxin FldA PSHAa1639 73 COG0716 FldA, Flavodoxins Energy production and conversion 77361523 Common rdgB inosine/xanthosine triphosphatase PSHAa2608 234 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 77360963 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase PSHAa2039 139 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 77359732 Common flaG flagellin protein PSHAa0783 14 COG1334 FlaG, Uncharacterized flagellar protein FlaG Cell motility and secretion 77361557 Common rpmB 50S ribosomal subunit protein L28 PSHAa2642 151 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 77361028 Nonpathogen - hypothetical protein PSHAa2104 2 None None None 77360270 Common - adenine DNA methylase PSHAa1327 28 COG3014 COG3014, Uncharacterized protein conserved in bacteria Function unknown 77361184 Common - conserved protein of unknown function with CYTH domain PSHAa2261 53 COG3025 COG3025, Uncharacterized conserved protein Function unknown 77361128 Common - hypothetical protein PSHAa2205 4 None None None 77359880 Common rluD 23S rRNA pseudouridine synthase D PSHAa0933 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 77361778 Common - conserved protein of unknown function highly conserved in gamma-proteobacteria PSHAa2875 90 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 77361282 Common dxs 1-deoxy-D-xylulose 5-phosphate synthase (DXP synthase) PSHAa2366 226 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 77361834 Common - unknown secreted protein PSHAa2932 5 None None None 77360974 Common pspF transcriptional activator of phage shock proteins (EBP) PSHAa2050 169 COG1221 PspF, Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain Transcription / Signal transduction mechanisms 77359506 Common arcB aerobic respiration control sensor protein ArcB PSHAa0550 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77361439 Common - conserved protein of unknown function, highly conserved in gamma-proteobacteria PSHAa2524 114 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 77361079 Common - thioesterase domain PSHAa2156 21 COG0824 FcbC, Predicted thioesterase General function prediction only 77360861 Common - hypothetical protein PSHAa1929 14 None None None 77359403 Common - tonB-dependent receptor PSHAa0437 41 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 77360973 Common pspA negative regulatory gene for the psp opreon, phage shock protein PSHAa2049 66 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 77359687 Common - hypothetical protein PSHAa0736 37 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 77360636 Common - hypothetical protein PSHAa1695 3 None None None 77360655 Common lolA periplasmic chaperone effects translocation of lipoproteins from inner membrane to outer membrane PSHAa1715 73 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 77359674 Common - hypothetical protein PSHAa0723 49 COG2938 COG2938, Uncharacterized conserved protein Function unknown 77360016 Common - hypothetical protein PSHAa1073 5 None None None 77361485 Common rarD uncharacterized transport protein PSHAa2570 100 COG2962 RarD, Predicted permeases General function prediction only 77359565 Common - hypothetical protein PSHAa0612 11 None None None 77361289 Common ribE riboflavin synthase subunit alpha PSHAa2373 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 77360800 Common phoD alkaline phosphatase D PSHAa1860 27 COG3540 PhoD, Phosphodiesterase/alkaline phosphatase D Inorganic ion transport and metabolism 77361693 Common chlD anion transport protein (ABC superfamily, ATP-binding protein) PSHAa2778 249 COG1119 ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA Inorganic ion transport and metabolism 77359204 Common exeE general secretion pathway protein E PSHAa0233 212 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 77360501 Common - hypothetical protein PSHAa1560 40 COG4445 MiaE, Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 77361119 Common baeS sensory transduction histidine kinase in two-component regulatory system with baeR PSHAa2196 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77361734 Common - hypothetical protein PSHAa2830 31 COG3021 COG3021, Uncharacterized protein conserved in bacteria Function unknown 77360886 Common - hypothetical protein PSHAa1958 5 None None None 77360991 Common lpxH UDP-2,3-diacylglucosamine hydrolase PSHAa2067 74 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 77359844 Common - enzyme PSHAa0895 10 None None None 77359704 Nonpathogen - hypothetical protein PSHAa0753 2 None None None 77359306 Common - hypothetical protein PSHAa0339 19 None None None 77359619 Common rpiA ribose-5-phosphate isomerase A PSHAa0667 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 77361477 Common - ABC transporter periplasmic substrate-binding protein PSHAa2562 148 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 77361434 Common - ribonuclease protein PSHAa2519 117 COG1295 Rbn, Predicted membrane protein Function unknown 77359891 Common rimM 16S rRNA processing protein PSHAa0945 173 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 77359498 Common - oxidoreductase, Aldo/keto reductase PSHAa0541 191 COG4989 COG4989, Predicted oxidoreductase General function prediction only 77360945 Common cydD cysteine transport (export) protein (ABC superfamily, membrane (N-terminal), atp_bind (C-terminal)) PSHAa2021 249 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 77359441 Common - TonB-dependent receptor PSHAa0476 97 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 77360776 Common mfd transcription-repair ATP-dependent coupling factor PSHAa1836 237 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 77359963 Common - hypothetical protein PSHAa1017 52 COG2234 Iap, Predicted aminopeptidases General function prediction only 77359078 Common - sensor protein PSHAa0101 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77360964 Nonpathogen - hypothetical protein PSHAa2040 2 None None None 77361720 Common rpsH 30S ribosomal protein S8 PSHAa2816 222 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 77360976 Common sapB peptide transport protein (ABC superfamily, membrane) PSHAa2052 219 COG4168 SapB, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 77359176 Nonpathogen - hypothetical protein PSHAa0205 1 None None None 77359065 Common - hypothetical protein PSHAa0088 15 None None None 77359976 Common rlpB minor lipoprotein PSHAa1030 26 COG2980 RlpB, Rare lipoprotein B Cell envelope biogenesis, outer membrane 77359475 Common prfB peptide chain release factor 2 (RF-2) PSHAa0517 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 77359428 Common fbp fructose-1,6-bisphosphatase PSHAa0463 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 77359964 Common - hypothetical protein PSHAa1018 62 COG0724 COG0724, RNA-binding proteins (RRM domain) General function prediction only 77361104 Common - hypothetical protein PSHAa2181 20 COG3247 HdeD, Uncharacterized conserved protein Function unknown 77360724 Nonpathogen - hypothetical protein PSHAa1784 1 None None None 77360118 Common - hypothetical protein PSHAa1175 80 COG1742 COG1742, Uncharacterized conserved protein Function unknown 77360949 Common fabZ (3R)-hydroxymyristol acyl carrier protein dehydratase PSHAa2025 187 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 77360245 Common - enzyme PSHAa1302 7 None None None 77359644 Common mutS DNA mismatch repair protein PSHAa0692 202 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 77359452 Common orn oligoribonuclease PSHAa0488 88 COG1949 Orn, Oligoribonuclease (3'->5' exoribonuclease) RNA processing and modification 77359741 Common fliF flagellar MS-ring protein PSHAa0792 125 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 77359102 Common yifB regulator PSHAa0130 192 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 77360477 Nonpathogen - hypothetical protein PSHAa1536 1 None None None 77358985 Common recF gap repair protein PSHAa0003 166 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 77360996 Common dedD hypothetical protein PSHAa2072 28 COG3147 DedD, Uncharacterized protein conserved in bacteria Function unknown 77360314 Common - peptidase M13 protein PSHAa1371 63 COG3590 PepO, Predicted metalloendopeptidase Posttranslational modification, protein turnover, chaperones 77360269 Common - hypothetical protein PSHAa1326 9 COG5633 COG5633, Predicted periplasmic lipoprotein General function prediction only 77361088 Common bcsC cellulose synthase operon protein C PSHAa2165 34 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 77361747 Common - transport protein PSHAa2844 57 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 77359386 Nonpathogen - hypothetical protein PSHAa0420 1 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 77360261 Common mrp ATPase of the MinD/MRP superfamily PSHAa1318 235 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 77359673 Common ygfZ transcriptional regulator PSHAa0722 94 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 77361304 Common - cytosol aminopeptidase PSHAa2388 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 77359888 Nonpathogen - hypothetical protein PSHAa0941 1 None None None 77361650 Common hutG formiminoglutamate hydrolase PSHAa2735 13 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 77360986 Common clpP ATP-dependent Clp protease proteolytic subunit (Endopeptidase Clp) (Caseinolytic protease) (Protease Ti)(Heat shock protein F21.5) PSHAa2062 212 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 77360671 Common - hypothetical protein PSHAa1731 10 None None None 77361840 Common mdoH glucosyltransferase MdoH PSHAa2938 61 COG2943 MdoH, Membrane glycosyltransferase Cell envelope biogenesis, outer membrane 77360463 Common - hypothetical protein PSHAa1522 13 COG2842 COG2842, Uncharacterized ATPase, putative transposase General function prediction only 77360774 Common - hypothetical protein PSHAa1834 87 COG2957 COG2957, Peptidylarginine deiminase and related enzymes Amino acid transport and metabolism 77360349 Common pykA pyruvate kinase PSHAa1406 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 77361284 Common - phosphatidylglycerophosphatase PSHAa2368 105 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 77359870 Common algR alginate biosynthesis regulatory protein PSHAa0923 210 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 77360745 Common pabC 4-amino-4-deoxychorismate lyase (aminotransferase), component of p-aminobenzoate synthase multienzyme complex PSHAa1805 143 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 77361518 Common pilT twitching motility protein PilT (type IV pili) PSHAa2603 217 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 77361451 Common degQ periplasmic serine endoprotease PSHAa2536 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 77361242 Common - 3-deoxy-D-manno-octulosonic-acid kinase PSHAa2319 20 COG3642 COG3642, Mn2+-dependent serine/threonine protein kinase Signal transduction mechanisms 77361201 Common - hypothetical protein PSHAa2278 3 COG5652 COG5652, Predicted integral membrane protein Function unknown 77359218 Common rdoA predicted kinase PSHAa0247 53 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 77360273 Common - D-alanyl-D-alanine carboxypeptidase PSHAa1330 24 COG1876 VanY, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 77361259 Common - thioredoxin-like protein PSHAa2342 67 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 77361432 Common - pirin protein PSHAa2517 148 COG1741 COG1741, Pirin-related protein General function prediction only 77360592 Common sdhC succinate dehydrogenase, hydrophobic subunit, cytochrome b556 with sdhD PSHAa1651 80 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 77360237 Common trpH conserved enzyme (phosphoesterase domain) PSHAa1294 131 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 77361456 Common - ABC-type transport system, auxiliary component PSHAa2541 56 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 77359483 Common - glutathione S-transferase PSHAa0526 109 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 77360533 Common uhpB sensory histidine kinase in two-component regulatory system with UhpA, regulates uhpT expression PSHAa1592 144 COG3851 UhpB, Signal transduction histidine kinase, glucose-6-phosphate specific Signal transduction mechanisms 77359549 Common pgk phosphoglycerate kinase PSHAa0595 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 77359532 Common - metal ion efflux outer membrane factor protein PSHAa0577 46 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 77361369 Common - sodium:dicarboxylate symporter PSHAa2453 163 COG1823 COG1823, Predicted Na+/dicarboxylate symporter General function prediction only 77360783 Common - Cbb3-type cytochrome oxidase, cytochrome c subunit PSHAa1843 82 COG2993 CcoO, Cbb3-type cytochrome oxidase, cytochrome c subunit Energy production and conversion 77359138 Common glnA glutamine synthetase PSHAa0166 225 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 77361346 Common - hypothetical protein PSHAa2430 8 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 77361818 Common - hypothetical protein PSHAa2916 2 COG3110 COG3110, Uncharacterized protein conserved in bacteria Function unknown 77361832 Common - Sec-independent protein translocase protein TatB PSHAa2930 27 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 77359131 Common acnA aconitate hydratase PSHAa0159 222 COG1048 AcnA, Aconitase A Energy production and conversion 77359278 Common pstB phosphate-transporting ATPase PSHAa0311 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 77361915 Common mnmG tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA PSHAa3019 192 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 77361252 Common - hypothetical protein ; signal peptide PSHAa2329 23 None None None 77359493 Common - hypothetical protein PSHAa0536 5 None None None 77360387 Common msrC probable secreted protein-methione-sulfoxide reductase with methionine-S-sulfoxide and methionine-R-sulfoxide reductase activity; signal peptide MSYQGLIYLSSVAILFSASSVA PSHAa1444 206 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 77360690 Common - tartronate semialdehyde reductase (TSAR) PSHAa1750 193 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 77361480 Common - Iron-compound ABC transporter permease protein PSHAa2565 192 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 77359942 Common nusA transcription elongation factor NusA PSHAa0996 219 COG0195 NusA, Transcription elongation factor Transcription 77359378 Common - hypothetical protein PSHAa0412 34 None None None 77361292 Common glyA serine hydroxymethyltransferase PSHAa2376 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 77359407 Common - transport protein (MFS) PSHAa0442 207 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77360678 Nonpathogen - hypothetical protein PSHAa1738 1 None None None 77361579 Nonpathogen - hypothetical protein PSHAa2664 1 None None None 77359554 Nonpathogen - hypothetical protein PSHAa0600 1 None None None 77361138 Common - transcriptional regulator LysR PSHAa2215 179 COG0583 LysR, Transcriptional regulator Transcription 77359511 Common - hypothetical protein PSHAa0555 72 COG2924 COG2924, Uncharacterized protein conserved in bacteria Function unknown 77361004 Common fabB 3-oxoacyl-[acyl-carrier-protein] synthase I PSHAa2080 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 77359040 Common - hypothetical protein PSHAa0063 17 COG4392 COG4392, Predicted membrane protein Function unknown 77360517 Nonpathogen - hypothetical protein PSHAa1576 1 None None None 77361328 Nonpathogen - hypothetical protein PSHAa2412 1 None None None 77359596 Common - hypothetical protein PSHAa0643 190 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 77359861 Common - chemotaxis protein PSHAa0913 219 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77360147 Nonpathogen - hypothetical protein PSHAa1204 1 None None None 77359101 Common - hypothetical protein PSHAa0129 133 COG2860 COG2860, Predicted membrane protein Function unknown 77360282 Common xthA exonuclease III PSHAa1339 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 77361153 Common cyoB Ubiquinol oxidase polypeptide I (Cytochrome o subunit 1) (Oxidase BO(3) subunit 1) (Cytochrome o ubiquinol oxidase subunit 1) (Ubiquinol oxidase chain A) PSHAa2230 165 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 77361239 Common kbl 2-amino-3-ketobutyrate coenzyme A ligase PSHAa2316 192 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 77360061 Nonpathogen - hypothetical protein PSHAa1118 1 None None None 77359072 Common cyaY iron scavenging protein PSHAa0095 43 COG1965 CyaY, Protein implicated in iron transport, frataxin homolog Inorganic ion transport and metabolism 77360401 Common - Enoyl-CoA hydratase/isomerase protein PSHAa1458 131 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 77359897 Common - hypothetical protein; conserved domain PSHAa0951 183 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 77360499 Nonpathogen - hypothetical protein PSHAa1558 1 None None None 77360206 Common - hypothetical protein PSHAa1263 28 COG4539 COG4539, Predicted membrane protein Function unknown 77359089 Common rho transcription termination factor Rho PSHAa0112 202 COG1158 Rho, Transcription termination factor Transcription 77359829 Common - NADPH dehydrogenase PSHAa0880 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 77360258 Nonpathogen - hypothetical protein PSHAa1315 1 None None None 77359776 Common ccmF cytochrome c-type biogenesis protein ccmF PSHAa0827 139 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 77360330 Common - transcriptional regulator PSHAa1387 115 COG0583 LysR, Transcriptional regulator Transcription 77359026 Common fumC fumarate hydratase PSHAa0048 229 COG0114 FumC, Fumarase Energy production and conversion 77361465 Common - transport protein (ABC superfamily, atp-binding protein) PSHAa2550 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 77359360 Common - hypothetical protein PSHAa0394 38 COG3148 COG3148, Uncharacterized conserved protein Function unknown 77360942 Common cydA cytochrome d terminal oxidase, polypeptide subunit I PSHAa2018 165 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 77361740 Common - hypothetical protein PSHAa2836 55 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 77359393 Common - transcriptional activator for lysine biosynthesis PSHAa0427 188 COG0583 LysR, Transcriptional regulator Transcription 77360221 Common - epimerase PSHAa1278 110 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 77361576 Common fbpC Iron(III) ABC transporter ATP-binding protein PSHAa2661 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 77359866 Common lspA lipoprotein signal peptidase (SPase II)(Prolipoprotein signal peptidase) PSHAa0919 197 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 77359018 Common - spermidine synthase PSHAa0040 111 COG4262 COG4262, Predicted spermidine synthase with an N-terminal membrane domain General function prediction only 77361094 Common - Integral membrane protein PSHAa2171 33 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 77361176 Common - hypothetical protein PSHAa2253 88 COG1981 COG1981, Predicted membrane protein Function unknown 77361723 Common rplX 50S ribosomal subunit protein L24 PSHAa2819 211 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 77361532 Common - hypothetical protein PSHAa2617 21 COG3313 COG3313, Predicted Fe-S protein General function prediction only 77360760 Nonpathogen - hypothetical protein PSHAa1820 1 None None None 77360096 Common - hypothetical protein PSHAa1153 2 None None None 77359193 Common rpoB DNA-directed RNA polymerase subunit beta PSHAa0222 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 77361886 Common - hypothetical protein PSHAa2984 2 None None None 77361515 Common yqgE hypothetical protein PSHAa2600 130 COG1678 COG1678, Putative transcriptional regulator Transcription 77360488 Nonpathogen - hypothetical protein PSHAa1547 2 None None None 77361855 Nonpathogen - hypothetical protein PSHAa2953 1 None None None 77359980 Common - Peptidyl-prolyl cis-trans isomerase, FKBP-type PSHAa1034 136 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 77361813 Common tufB elongation factor Tu PSHAa2911 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 77361547 Common imp organic solvent tolerance protein PSHAa2632 124 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 77359904 Common - hypothetical protein PSHAa0958 8 None None None 77361133 Common - hypothetical protein PSHAa2210 45 COG4102 COG4102, Uncharacterized protein conserved in bacteria Function unknown 77359822 Common tpiA triosephosphate isomerase PSHAa0873 229 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 77360651 Nonpathogen - hypothetical protein PSHAa1710 1 None None None 77359881 Common - hypothetical protein PSHAa0934 181 COG1496 COG1496, Uncharacterized conserved protein Function unknown 77359576 Common - hypothetical protein PSHAa0623 13 None None None 77359143 Common dtd D-tyrosyl-tRNA deacylase PSHAa0172 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 77360514 Common purE phosphoribosylaminoimidazole carboxylase catalytic subunit PSHAa1573 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 77359796 Common - hypothetical protein ; TPR domain protein PSHAa0847 30 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 77359571 Common - calcium dependent protein PSHAa0618 4 None None None 77360608 Common - methyltransferase with S-adenosyl-L-methionine-dependent methyltransferase domain PSHAa1667 163 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 77360363 Common ubiG 3-demethylubiquinone-9 3-methyltransferase PSHAa1420 147 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 77361232 Common - prolyl 4-hydroxylase, alpha subunit domain PSHAa2309 30 COG3751 EGL-9, Predicted proline hydroxylase Posttranslational modification, protein turnover, chaperones 77360646 Common - manganese/divalent cation transport protein (NRAMP) PSHAa1705 122 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 77359412 Common mutM formamidopyrimidine DNA glycosylase PSHAa0447 181 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 77359442 Common - thioesterase superfamily PSHAa0477 36 COG0824 FcbC, Predicted thioesterase General function prediction only 77359011 Common hemF coproporphyrinogen III oxidase PSHAa0029 113 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 77359234 Common - hypothetical protein PSHAa0267 208 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 77360867 Common - protein mcbG PSHAa1935 57 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 77359213 Common - general secretion pathway protein N PSHAa0242 14 None None None 77360426 Common - hypothetical protein PSHAa1483 19 COG2314 XynA, Predicted membrane protein Function unknown 77360001 Common prfA Peptide chain release factor 1 (RF-1) PSHAa1058 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 77360630 Common - hypothetical protein PSHAa1689 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 77360103 Common - hypothetical protein PSHAa1160 157 COG2252 COG2252, Permeases General function prediction only 77361569 Common obgE GTPase ObgE PSHAa2654 249 COG0536 Obg, Predicted GTPase General function prediction only 77361277 Common - DNA topoisomerase III PSHAa2361 78 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 77361441 Common sspB ClpXP protease specificity-enhancing factor PSHAa2526 64 COG2969 SspB, Stringent starvation protein B General function prediction only 77360924 Common - hypothetical protein PSHAa2000 69 COG2391 COG2391, Predicted transporter component General function prediction only 77359436 Common - hypothetical protein PSHAa0471 5 None None None 77359013 Common aroE 5-dehydroshikimate reductase PSHAa0031 219 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 77359727 Common flgJ flagellar biosynthesis PSHAa0777 66 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 77360032 Common - peptidase PSHAa1089 196 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 77359354 Common ampD N-acetyl-anhydromuranmyl-L-alanine amidase PSHAa0388 107 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 77360010 Common ygdE RNA 2'-O-ribose methyltransferase, SAM-dependent domain PSHAa1067 46 COG2933 COG2933, Predicted SAM-dependent methyltransferase General function prediction only 77359359 Common lpd dihydrolipoamide dehydrogenase PSHAa0393 240 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 77360442 Common moxR MoxR protein PSHAa1500 181 COG0714 COG0714, MoxR-like ATPases General function prediction only 77360450 Common - hypothetical protein PSHAa1509 29 COG4383 COG4383, Mu-like prophage protein gp29 Function unknown 77359283 Nonpathogen - hypothetical protein PSHAa0316 1 None None None 77359423 Common - protozoan/cyanobacterial globin protein PSHAa0458 21 COG2346 COG2346, Truncated hemoglobins General function prediction only 77359448 Common thiDE phosphomethylpyrimidine kinase/thiamin-phosphate pyrophosphorylase PSHAa0484 224 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 77361162 Common nqrC Na(+)-translocating NADH-quinone reductase subunit C PSHAa2239 47 COG2869 NqrC, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC Energy production and conversion 77361397 Common - permease PSHAa2482 142 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 77360433 Common rmf ribosome modulation factor PSHAa1490 21 COG3130 Rmf, Ribosome modulation factor Translation, ribosomal structure and biogenesis 77359405 Common - hydrolase activity(metallophosphoesterase) PSHAa0439 5 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 77359349 Common - pilus biogenesis protein PSHAa0383 16 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 77359774 Common ccmD heme exporter protein D (Cytochrome c-type biogenesis protein ccmD) PSHAa0825 22 COG3114 CcmD, Heme exporter protein D Intracellular trafficking and secretion 77359242 Common purA adenylosuccinate synthetase PSHAa0275 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 77361096 Common - transporter PSHAa2173 136 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77361695 Nonpathogen - hypothetical protein PSHAa2780 1 None None None 77361667 Common - Cytochrome c4 PSHAa2752 62 COG2863 COG2863, Cytochrome c553 Energy production and conversion 77360792 Common - conserved protein of unknown function, contains adenine nucleotide alpha hydrolase domain PSHAa1852 163 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 77359873 Nonpathogen - hypothetical protein PSHAa0926 2 None None None 77359205 Common gspF general secretion pathway protein F PSHAa0234 143 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 77360875 Common - Adenylosuccinate synthetase PSHAa1943 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 77359156 Common - biofilm formation protein PSHAa0185 31 COG4340 COG4340, Uncharacterized protein conserved in bacteria Function unknown 77360186 Common mrsAB methionine sulfoxide reductase A PSHAa1243 204 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 77360417 Common - hypothetical protein PSHAa1474 18 None None None 77361736 Common - multidrug efflux system (AcrA/AcrE) PSHAa2832 165 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 77359082 Common ubiD 3-octaprenyl-4-hydroxybenzoate carboxylyase PSHAa0105 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 77360457 Nonpathogen - hypothetical protein PSHAa1516 1 None None None 77360579 Common - LexA regulated protein PSHAa1638 21 None None None 77360805 Common - cytochrome C PSHAa1865 35 COG3258 COG3258, Cytochrome c Energy production and conversion 77361195 Common - conserved protein of unknown function; membrane protein PSHAa2272 161 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 77361388 Common gcvP glycine dehydrogenase PSHAa2473 173 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 77359249 Common - hypothetical protein PSHAa0282 28 COG3760 COG3760, Uncharacterized conserved protein Function unknown 77361503 Common - enzyme with alpha/beta-hydrolase-like domain PSHAa2588 47 COG3150 COG3150, Predicted esterase General function prediction only 77361065 Common mhpF acetaldehyde dehydrogenase PSHAa2142 37 COG4569 MhpF, Acetaldehyde dehydrogenase (acetylating) Secondary metabolites biosynthesis, transport, and catabolism 77361684 Common ilvD dihydroxyacid dehydratase; possibly homodimieric PSHAa2769 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 77361616 Common - protein with EAL domain PSHAa2701 65 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 77359297 Nonpathogen - hypothetical protein PSHAa0330 1 None None None 77360871 Common - hypothetical protein PSHAa1939 105 COG1801 COG1801, Uncharacterized conserved protein Function unknown 77361828 Common ubiE 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase / S-adenosylmethionine PSHAa2926 220 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 77359803 Common rstB sensory histidine kinase in two-component regulatory system with RstA PSHAa0854 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77361867 Common - unknown membrane associated protein PSHAa2965 27 COG3402 COG3402, Uncharacterized conserved protein Function unknown 77361387 Nonpathogen - hypothetical protein PSHAa2472 1 None None None 77359223 Common murI glutamate racemase PSHAa0252 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 77359504 Common - hypothetical protein PSHAa0548 10 None None None 77360734 Common - hypothetical protein PSHAa1794 35 COG3672 COG3672, Predicted periplasmic protein Function unknown 77359451 Common - ribosome-associated GTPase PSHAa0487 163 COG1162 COG1162, Predicted GTPases General function prediction only 77360193 Common lysC aspartate kinase III PSHAa1250 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 77360399 Common - Acyl-CoA dehydrogenase protein PSHAa1456 167 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77359566 Common - hypothetical protein PSHAa0613 12 COG5616 COG5616, Predicted integral membrane protein Function unknown 77361797 Common leuA 2-isopropylmalate synthase PSHAa2894 216 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 77361562 Common - conserved protein of unknown function with GGDEF domain PSHAa2647 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 77360167 Common - hypothetical protein PSHAa1224 131 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 77360414 Common - hypothetical protein PSHAa1471 24 None None None 77360952 Common ecfK outer membrane protein assembly factor PSHAa2028 152 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 77359166 Common astA arginine succinyltransferase PSHAa0195 37 COG3138 AstA, Arginine/ornithine N-succinyltransferase beta subunit Amino acid transport and metabolism 77360322 Common - hypothetical protein PSHAa1379 117 COG1285 SapB, Uncharacterized membrane protein Function unknown 77359049 Common folX D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase PSHAa0072 53 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 77360382 Common - hypothetical protein PSHAa1439 58 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 77359747 Common fliL flagellar basal body-associated protein FliL PSHAa0798 19 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 77361421 Common murD UDP-N-acetylmuramoylalanine-D-glutamate ligase PSHAa2506 207 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 77360704 Common - endoribonuclease L-PSP domain PSHAa1764 172 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 77359631 Common - ATPase PSHAa0679 93 COG0714 COG0714, MoxR-like ATPases General function prediction only 77360947 Common - rlpA-like lipoprotein precursor PSHAa2023 136 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 77360297 Common - alpha-amylase PSHAa1354 163 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 77359949 Common - hypothetical protein PSHAa1003 2 None None None 77361425 Common ftsI division-specific transpeptidase, penicillin-binding protein 3 PSHAa2510 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 77359262 Common - hypothetical protein PSHAa0295 3 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 77361716 Common rpmD 50S ribosomal protein L30 PSHAa2812 146 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 77359161 Common glpK glycerol kinase PSHAa0190 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 77360602 Common msbA lipid transport protein PSHAa1661 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 77360215 Common - hypothetical protein PSHAa1272 21 COG4323 COG4323, Predicted membrane protein Function unknown 77359516 Common - hypothetical protein PSHAa0561 41 COG3079 COG3079, Uncharacterized protein conserved in bacteria Function unknown 77359477 Nonpathogen - hypothetical protein PSHAa0519 1 None None None 77359837 Common - acyl-CoA dehydrogenase protein PSHAa0888 153 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77361183 Common - conserved protein of unknown function with carboxypeptidase C domain PSHAa2260 37 COG2939 COG2939, Carboxypeptidase C (cathepsin A) Amino acid transport and metabolism 77360830 Common - iron-sulfur cluster-binding protein FixG PSHAa1892 82 COG0348 NapH, Polyferredoxin Energy production and conversion 77360025 Common - Cell division protein zipA homolog PSHAa1082 40 COG3115 ZipA, Cell division protein Cell division and chromosome partitioning 77359269 Common - hypothetical protein PSHAa0302 3 None None None 77361215 Common argE acetylornithine deacetylase PSHAa2292 202 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 77361790 Common - hypothetical protein PSHAa2887 39 COG4103 COG4103, Uncharacterized protein conserved in bacteria Function unknown 77361544 Common djlA Dna-J like membrane chaperone protein PSHAa2629 60 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 77361228 Common - hypothetical protein PSHAa2305 26 COG3068 COG3068, Uncharacterized protein conserved in bacteria Function unknown 77361147 Common metA homoserine O-succinyltransferase PSHAa2224 64 COG1897 MetA, Homoserine trans-succinylase Amino acid transport and metabolism 77359594 Common - ATP-dependent RNA helicase PSHAa0641 237 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 77359469 Common - SAM-dependent methyltransferase(yfiC) PSHAa0511 60 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 162139930 Common acnB bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase PSHAa0184 219 COG1049 AcnB, Aconitase B Energy production and conversion 77360940 Common rnhB RNAse HII PSHAa2016 237 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 77360644 Common avtA valine--pyruvate transaminase PSHAa1703 182 COG3977 COG3977, Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase Amino acid transport and metabolism 77358991 Common sirA small ubiquitous RNA-binding protein PSHAa0009 84 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 77360465 Nonpathogen - hypothetical protein PSHAa1524 1 None None None 77361620 Common ssb Single-strand binding protein (SSB) (Helix-destabilizing protein) PSHAa2705 213 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 77359365 Common bhbD 3-hydroxybutyryl-CoA dehydrogenase PSHAa0399 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 77360598 Common - 23S rRNA pseudouridylate synthase PSHAa1657 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 77359738 Common - sensory box sensor histidine kinase in two-component regulatory system PSHAa0789 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77359682 Common lepB signal peptidase I PSHAa0731 206 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 77360839 Common - hypothetical protein PSHAa1901 7 None None None 77361555 Nonpathogen - hypothetical protein PSHAa2640 1 None None None 77359458 Common pspA negative regulatory gene for the psp operon, phage shock protein A PSHAa0500 80 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 77359678 Common rseA anti sigma E (sigma 24) factor, negative regulator PSHAa0727 24 COG3073 RseA, Negative regulator of sigma E activity Signal transduction mechanisms 77361131 Common mtD Mannitol dehydrogenase (NAD-dependent mannitol dehydrogenase) PSHAa2208 205 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 77360370 Common - hypothetical protein PSHAa1427 11 COG3771 COG3771, Predicted membrane protein Function unknown 77359993 Common ubiF 2-octoprenyl-3-methyl-6-methoxy-1, 4-benzoquinone hydroxylase PSHAa1047 130 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 77359129 Nonpathogen - hypothetical protein PSHAa0157 1 None None None 77359110 Nonpathogen - hypothetical protein PSHAa0138 1 None None None 77360591 Common sdhD succinate dehydrogenase, hydrophobic subunit, cytochrome b556 with sdhC PSHAa1650 48 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 77361240 Common gmhB heptose 1,7-bisphosphate phosphatase PSHAa2317 133 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 77360983 Common hupB DNA-binding protein PSHAa2059 204 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 77361641 Common rpmE 50S ribosomal subunit protein L31 PSHAa2726 208 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 77359606 Common rimI ribosomal-protein-alanine acetyltransferase (Acetylating enzyme for N-terminal of ribosomal protein S18) PSHAa0653 161 COG0456 RimI, Acetyltransferases General function prediction only 77359627 Nonpathogen - hypothetical protein PSHAa0675 2 None None None 77360243 Common - hypothetical protein PSHAa1300 2 None None None 77360348 Common - response regulator in two-component regulatory system PSHAa1405 216 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 77359628 Common - transposase (IS492) PSHAa0676 65 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 77360140 Common - hypothetical protein PSHAa1197 62 COG3220 COG3220, Uncharacterized protein conserved in bacteria Function unknown 77360614 Common - hypothetical protein PSHAa1673 18 None None None 77359003 Common rsmB 16S rRNA methyltransferase PSHAa0021 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 77359338 Common - transport protein PSHAa0372 187 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 77361390 Common gcvT glycine cleavage system aminomethyltransferase T PSHAa2475 179 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 77359255 Nonpathogen - hypothetical protein PSHAa0288 3 None None None 77360932 Common - hypothetical protein PSHAa2008 12 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 77361847 Common metX homoserine O-acetyltransferase PSHAa2945 129 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 77359830 Common teiR LuxR-type transcription regulator required for testosterone degradation PSHAa0881 34 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 77360037 Common - amino acid decarboxylase PSHAa1094 89 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 77359189 Common rplK 50S ribosomal subunit protein L11 PSHAa0218 248 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 77361076 Common - dehydrogenase PSHAa2153 226 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 77360939 Common dnaE DNA polymerase III subunit alpha PSHAa2015 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 77360122 Nonpathogen - hypothetical protein PSHAa1179 1 None None None 77361522 Common - hypothetical protein PSHAa2607 13 None None None 77361771 Common - transmembrane cytochrome oxidase complex biogenesis factor PSHAa2868 30 COG3346 COG3346, Uncharacterized conserved protein Function unknown 77360961 Common map methionine aminopeptidase; contains a divalent metal, usually cobalt PSHAa2037 248 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 77360988 Common folD bifunctional: 5,10-methylene-tetrahydrofolate dehydrogenase; 5,10-methylene-tetrahydrofolate cyclohydrolase PSHAa2064 223 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 77359706 Common - hypothetical protein PSHAa0755 10 COG5616 COG5616, Predicted integral membrane protein Function unknown 77360766 Common - sigma factor PSHAa1826 34 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 77361708 Common recG ATP-dependent DNA helicase PSHAa2799 223 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 77359561 Common sfsA transcriptional regulator PSHAa0607 107 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 77359751 Common fliP flagellar biosynthesis protein FliP PSHAa0802 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 77361143 Common - hypothetical protein PSHAa2220 15 None None None 77361767 Common - SCO1/SenC protein (copper-binding protein) PSHAa2864 101 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 77361330 Common - transcriptional regulator PSHAa2414 24 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 77360553 Common - ABC-type transport system, periplasmic component PSHAa1612 83 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 77359783 Common - DNA damage-inducible gene in SOS regulon, dependent on cyclic AMP and H-NS PSHAa0834 21 COG3141 COG3141, Uncharacterized protein conserved in bacteria Function unknown 77360111 Common - Chloramphenicol acetyltransferase PSHAa1168 22 COG4845 COG4845, Chloramphenicol O-acetyltransferase Defense mechanisms 77361323 Common - TonB-dependent receptor protein PSHAa2407 118 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 77361032 Common - Hypothetical gene (partial) PSHAa2109 5 None None None 77360091 Common - two-component regulator with metal-dependent phosphohydrolase, HD region PSHAa1148 58 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 162139923 Common uvrC excinuclease ABC subunit C PSHAa1915 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 77360153 Common - response regulator PSHAa1210 205 COG1776 CheC, Chemotaxis protein CheC, inhibitor of MCP methylation Cell motility and secretion / Signal transduction mechanisms 77360689 Common - alginate lyase precursor PSHAa1749 7 None None None 77361044 Nonpathogen - hypothetical protein PSHAa2121 2 None None None 77361592 Common - hypothetical protein PSHAa2677 56 COG3164 COG3164, Predicted membrane protein Function unknown 77359063 Nonpathogen - hypothetical protein PSHAa0086 1 None None None 77359036 Common - transcriptional regulator PSHAa0059 227 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 77361460 Common - Na:Ca transport protein (CacA) PSHAa2545 135 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 77359182 Common cysN ATP-sulfurylase subunit 1 PSHAa0211 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 77361112 Common - Transcriptional regulator, LysR PSHAa2189 179 COG0583 LysR, Transcriptional regulator Transcription 77360914 Common - DNA polymerase II PSHAa1990 64 COG0417 PolB, DNA polymerase elongation subunit (family B) DNA replication, recombination, and repair 77359233 Common accC acetyl-CoA carboxylase biotin carboxylase subunit PSHAa0266 230 COG0439 AccC, Biotin carboxylase Lipid metabolism 77361892 Common - hypothetical protein PSHAa2990 36 COG2378 COG2378, Predicted transcriptional regulator Transcription 77359290 Common suhB inositol-1-monophosphatase PSHAa0323 215 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 77361206 Nonpathogen - membrane protein; triplicated sequence PSHAa2283 1 None None None 77361218 Common - methyltransferase SAM dependent PSHAa2295 18 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 77361337 Common - hypothetical protein PSHAa2421 110 COG0795 COG0795, Predicted permeases General function prediction only 77361821 Common - control sensor/kinase protein (ArcB, TorS, ChiS, LuxQ, BvgS) PSHAa2919 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77359273 Nonpathogen - hypothetical protein PSHAa0306 6 None None None 77360834 Common - hypothetical protein PSHAa1896 21 COG3139 COG3139, Uncharacterized protein conserved in bacteria Function unknown 77359053 Common - hypothetical protein PSHAa0076 41 COG3132 COG3132, Uncharacterized protein conserved in bacteria Function unknown 77360894 Common - flavodoxin PSHAa1969 77 COG0716 FldA, Flavodoxins Energy production and conversion 77359531 Nonpathogen - hypothetical protein PSHAa0576 1 None None None 77361566 Common - methyl-accepting chemotaxis protein PSHAa2651 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77359691 Common mazG Nucleoside triphosphate pyrophosphohydrolase, non-specific PSHAa0740 156 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 77360291 Common topA DNA topoisomerase I PSHAa1348 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 77361606 Common mshG Mannose-sensitive agglutinin (MSHA) biogenesis protein MshG (pilus type IV) PSHAa2691 150 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 77361302 Common - dipeptidyl peptidase IV PSHAa2386 110 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 77359789 Common - TonB-dependent receptor PSHAa0840 105 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 77361013 Nonpathogen - hypothetical protein PSHAa2089 1 None None None 77359782 Common putP sodium/proline symporter PSHAa0833 169 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 77360503 Common - hypothetical protein PSHAa1562 34 COG3788 COG3788, Uncharacterized relative of glutathione S-transferase, MAPEG superfamily General function prediction only 77359137 Common - hypothetical protein PSHAa0165 15 None None None 77359031 Common asnC transcriptional regulator PSHAa0053 152 COG1522 Lrp, Transcriptional regulators Transcription 77359818 Common rrmJ 23S rRNA methyltransferase J PSHAa0869 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 77360667 Common - Isocitrate dehydrogenase PSHAa1727 65 COG2838 Icd, Monomeric isocitrate dehydrogenase Energy production and conversion 77361593 Common rng ribonuclease G PSHAa2678 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 77358994 Common slt lytic murein transglycosylase PSHAa0012 164 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 77359371 Common - hypothetical protein PSHAa0405 111 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 77361760 Common bioH enzyme in pimeloyl-CoA (biotin precursor) synthesis with alpha/beta-hydrolase domain PSHAa2857 108 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77360784 Common - Cbb3-type cytochrome oxidase, subunit 3 PSHAa1844 4 COG4736 CcoQ, Cbb3-type cytochrome oxidase, subunit 3 Posttranslational modification, protein turnover, chaperones 77360461 Nonpathogen - hypothetical protein PSHAa1520 1 None None None 77361246 Common rfaE bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase PSHAa2323 172 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 77359667 Nonpathogen - inner membrane protein PSHAa0716 2 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 77361275 Common - phage integrase PSHAa2359 4 None None None 77360692 Common - hypothetical protein PSHAa1752 55 COG0730 COG0730, Predicted permeases General function prediction only 77361678 Common - hypothetical protein PSHAa2763 51 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 77361041 Nonpathogen - hypothetical protein PSHAa2118 1 None None None 77359912 Common fadI 3-ketoacyl-CoA thiolase PSHAa0966 175 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 77360575 Common pgm phosphoglucomutase PSHAa1634 195 COG0033 Pgm, Phosphoglucomutase Carbohydrate transport and metabolism 77361171 Common ampG muropeptide transport protein (mFS), highly conserved in gamma-proteobacteria PSHAa2248 100 None None None 77360623 Nonpathogen - hypothetical protein PSHAa1682 1 None None None 77359024 Nonpathogen - hypothetical protein PSHAa0046 2 None None None 77359344 Common pilB type IV pilus biogenesis protein PSHAa0378 216 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 77360823 Common - 3-ketoacyl-acyl carrier protein reductase 1 PSHAa1885 175 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77361906 Common atpA F0F1 ATP synthase subunit alpha PSHAa3010 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 77361124 Nonpathogen - hypothetical protein PSHAa2201 1 None None None 77361406 Common - hypothetical protein PSHAa2491 14 None None None 77361430 Common - hypothetical protein PSHAa2515 2 None None None 77361921 Common rnpA Ribonuclease P protein component (RNaseP protein) (RNase P protein) (Protein C5) PSHAa3025 71 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 77360267 Common - conserved protein of unknown function; secreted protein, conserved in gamma-proteobacteria PSHAa1324 15 COG3133 SlyB, Outer membrane lipoprotein Cell envelope biogenesis, outer membrane 77360594 Common gltA citrate synthase PSHAa1653 194 COG0372 GltA, Citrate synthase Energy production and conversion 77361453 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase PSHAa2538 216 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 77361690 Common cusR response regulator in two-component regulatory system with CusS, regulation of copper resistance PSHAa2775 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77360648 Common - dehydrogenase with soluble quinoprotein glucose dehydrogenase domain PSHAa1707 114 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 77361482 Common - Outer membrane porin PSHAa2567 42 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 77359525 Common - glyoxalase domain PSHAa0570 35 COG3565 COG3565, Predicted dioxygenase of extradiol dioxygenase family General function prediction only 77360922 Nonpathogen - hypothetical protein PSHAa1998 1 None None None 77360968 Common mdeA probable Methionine gamma-lyase PSHAa2044 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 77359534 Common czcA Cobalt-zinc-cadmium resistance protein czcA (Cation efflux system protein czcA) PSHAa0579 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 77361379 Common - hypothetical protein PSHAa2463 175 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 77361370 Common - hypothetical protein; membrane protein PSHAa2454 3 None None None 77361114 Common - rhomboid protein PSHAa2191 47 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 77359578 Common cca tRNA nucleotidyl transferase PSHAa0625 207 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 77359791 Common - hypothetical protein PSHAa0842 102 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 77359044 Common - hypothetical protein PSHAa0067 25 None None None 77359133 Common - hypothetical protein PSHAa0161 7 COG2501 COG2501, Uncharacterized conserved protein Function unknown 77361269 Nonpathogen - hypothetical protein PSHAa2353 4 None None None 77361290 Common ribD Riboflavin biosynthesis protein PSHAa2374 229 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 77361755 Nonpathogen - hypothetical protein PSHAa2852 1 None None None 77361344 Common - metal-dependent phosphohydrolase, HD region PSHAa2428 122 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 77359944 Common rbfA ribosome-binding factor A, role in processing of 16S rRNA PSHAa0998 175 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 77360054 Common - hypothetical protein PSHAa1111 139 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 77359542 Common - sodium/solute symporter protein PSHAa0587 169 COG4147 DhlC, Predicted symporter General function prediction only 77359998 Common ispE 4-diphosphocytidyl-2C-methyl-D-erythritol kinase (CMK) (4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase) PSHAa1055 194 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 77360208 Common - inner membrane protein PSHAa1265 40 COG3647 COG3647, Predicted membrane protein Function unknown 77360056 Nonpathogen - hypothetical protein PSHAa1113 1 None None None 77361006 Common - hypothetical protein PSHAa2082 81 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 77359352 Common nadC nicotinate-nucleotide pyrophosphorylase PSHAa0386 204 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 77360672 Common - conserved protein of unknown function with protein kinase-like domain PSHAa1732 70 COG3001 COG3001, Uncharacterized protein conserved in bacteria Function unknown 77361313 Common - hypothetical protein PSHAa2397 3 None None None 77361896 Common - transcriptional regulator PSHAa2995 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 77360385 Common - allophanate hydrolase PSHAa1442 115 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 77360376 Common - hypothetical protein PSHAa1433 110 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 77359495 Common oadG oxaloacetate decarboxylase, gamma subunit PSHAa0538 6 COG3630 OadG, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, gamma subunit Energy production and conversion 77361745 Common - lipoprotein PSHAa2842 175 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 77359104 Common - hydrolase PSHAa0132 118 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 77359303 Common - histone deacetylase PSHAa0336 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 77359496 Common oadA pyruvate carboxylase subunit B PSHAa0539 198 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 77359400 Nonpathogen - hypothetical protein PSHAa0434 1 None None None 77359149 Common dcdA diaminopimelate decarboxylase PSHAa0178 176 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 77359736 Common - flagellar regulatory protein A (polar flagellae) PSHAa0787 170 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77360546 Common htpX heat shock protein HtpX PSHAa1605 191 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 77359729 Common flgL flagellar hook-associated protein FlgL PSHAa0779 95 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 77361073 Common - MaoC-like deshydratase domain PSHAa2150 61 COG2030 MaoC, Acyl dehydratase Lipid metabolism 77360017 Common - hypothetical protein PSHAa1074 1 None None None 77360788 Common - cytochrome oxidase maturation protein, cbb3-type (partial match) PSHAa1848 14 COG3197 FixS, Uncharacterized protein, possibly involved in nitrogen fixation Inorganic ion transport and metabolism 77361262 Common - DNA topoisomerase III PSHAa2345 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 77360519 Nonpathogen - hypothetical protein PSHAa1578 1 None None None 77360510 Common - hypothetical protein PSHAa1569 22 None None None 77360929 Common - conserved protein of unknown function, some similarity with a Photorhabdus luminescens protein PSHAa2005 3 None None None 77359886 Common - hypothetical protein PSHAa0939 219 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 77361254 Common - transport binding protein PSHAa2331 135 COG4623 COG4623, Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein Cell envelope biogenesis, outer membrane 77359642 Common - lipoprotein NlpD precursor PSHAa0690 175 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 77359974 Common nadD nicotinic acid mononucleotide adenylyltransferase, NAD(P)-requiring PSHAa1028 136 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 77359174 Nonpathogen - hypothetical protein PSHAa0203 1 None None None 77361826 Common - hypothetical protein PSHAa2924 44 COG4805 COG4805, Uncharacterized protein conserved in bacteria Function unknown 77361351 Common dnaB replicative DNA helicase; chromosome replication; chain elongation PSHAa2435 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 77360979 Common sapF peptide transport protein (ABC superfamily, atp_bind) PSHAa2055 249 COG4167 SapF, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 77359988 Common cutE apolipoprotein N-acyltransferase copper homeostasis protein PSHAa1042 160 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 77359978 Common - hypothetical protein PSHAa1032 20 None None None 77361411 Common - NTPase PSHAa2496 36 COG1986 COG1986, Uncharacterized conserved protein Function unknown 77361520 Common proC Pyrroline-5-carboxylate reductase (NAD(P)-binding) PSHAa2605 215 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 77361731 Common - ABC transporter ATP-binding protein PSHAa2827 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 77361738 Common - Transcriptional regulator, ArsR PSHAa2834 72 COG0640 ArsR, Predicted transcriptional regulators Transcription 77359937 Common grxA glutaredoxin 1 PSHAa0991 28 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 77361356 Common rpsR 30S ribosomal subunit protein S18 PSHAa2440 215 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 77360390 Common - succinyl-CoA transferase, subunit A PSHAa1447 99 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 77361092 Common faH Fumarylacetoacetase (Fumarylacetoacetate hydrolase) (Beta-diketonase)(FAA) PSHAa2169 59 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 77360772 Common - Cryptic haloacid dehalogenase 1 (partial) PSHAa1832 94 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 77359827 Common - reductase protein PSHAa0878 145 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 77358987 Common glyQ glycyl-tRNA synthetase subunit alpha PSHAa0005 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 77361306 Nonpathogen - hypothetical protein PSHAa2390 1 None None None 77359489 Common alaS alanyl-tRNA synthetase PSHAa0532 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 77360994 Common purF amidophosphoribosyltransferase PSHAa2070 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 77359671 Nonpathogen - hypothetical protein ; membrane protein PSHAa0720 3 None None None 77359208 Common gspI general secretion pathway protein I PSHAa0237 26 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 77360481 Common - hypothetical protein PSHAa1540 12 None None None 77359277 Common pstA phosphate transport system permease protein PSHAa0310 225 COG4985 COG4985, ABC-type phosphate transport system, auxiliary component Inorganic ion transport and metabolism 77361402 Common - glutathione peroxidase precursor PSHAa2487 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 77361081 Common - membrane protein ; endoglucanase BcsG PSHAa2158 18 None None None 77360903 Common syd SecY interacting protein Syd PSHAa1979 19 None None None 77359953 Common - putative monovalent cation/H+ antiporter subunit E PSHAa1007 76 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 77361394 Common rlmB 23S rRNA (guanosine-2'-O-)-methyltransferase PSHAa2479 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 77361900 Common cobT nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase PSHAa2999 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 77360878 Common yecP methyltransferase with S-adenosyl-L-methionine-dependent methyltransferase domain PSHAa1946 81 COG0500 SmtA, SAM-dependent methyltransferases Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77359820 Common folP dihydropteroate synthase PSHAa0871 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 77359721 Common flgD flagellar basal body rod modification protein PSHAa0771 102 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 77359047 Common - hypothetical protein PSHAa0070 32 COG3296 COG3296, Uncharacterized protein conserved in bacteria Function unknown 77359228 Common - F exclusion suppressor PSHAa0261 75 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 77359794 Common - hypothetical protein PSHAa0845 38 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 77360098 Common - hypothetical protein PSHAa1155 12 None None None 77360470 Nonpathogen - hypothetical protein PSHAa1529 1 None None None 77361023 Nonpathogen - hypothetical protein PSHAa2099 1 None None None 77361567 Common - hypothetical protein PSHAa2652 4 None None None 77359662 Common - methyl-accepting chemotaxis protein PSHAa0711 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77361055 Common - acyl-CoA synthetase PSHAa2132 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 77361537 Common - PhoH-like protein PSHAa2622 198 COG1875 COG1875, Predicted ATPase related to phosphate starvation-inducible protein PhoH Signal transduction mechanisms 77361604 Common mshA Mannose-sensitive agglutinin (MSHA) biogenesis protein MshA (pilus type IV) PSHAa2689 4 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 77360747 Common acpP acyl carrier protein PSHAa1807 183 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 77361203 Common thiI thiamine biosynthesis protein ThiI PSHAa2280 94 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 77359460 Nonpathogen - inner membrane protein PSHAa0502 1 None None None 77359211 Common - general secretion pathway protein L PSHAa0240 23 COG3297 PulL, Type II secretory pathway, component PulL Intracellular trafficking and secretion 77360108 Common pabB aminodeoxychorismate synthase subunit I PSHAa1165 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 77360224 Nonpathogen - hypothetical protein PSHAa1281 1 None None None 77361409 Nonpathogen - hypothetical protein ; signal peptide PSHAa2494 5 None None None 77359518 Common ubiH 2-octaprenyl-6-methoxyphenol hydroxylase PSHAa0563 119 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 77361881 Common cspE RNA chaperone, transcription antiterminator, affects expression of rpoS and uspA PSHAa2979 179 COG1278 CspC, Cold shock proteins Transcription 77360361 Common nrdA ribonucleotide-diphosphate reductase subunit alpha PSHAa1418 201 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 77360582 Common fur ferric uptake regulator PSHAa1641 196 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 77361907 Common atpH membrane-bound ATP synthase, F1 sector, delta-subunit PSHAa3011 172 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 77359140 Common - hydrolase PSHAa0169 88 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 77359246 Common proB gamma-glutamyl kinase PSHAa0279 192 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 77361487 Common recQ ATP-dependent DNA helicase PSHAa2572 232 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 77360567 Common - sodium ABC exporter ATP-binding protein PSHAa1626 249 COG4555 NatA, ABC-type Na+ transport system, ATPase component Energy production and conversion / Inorganic ion transport and metabolism 77360970 Common - conserved protein of unknown function, with nucleotide triphosphate hydrolase domain PSHAa2046 42 COG3106 COG3106, Predicted ATPase General function prediction only 77360358 Common - outer membrane protein PSHAa1415 118 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 77359414 Common - hypothetical protein PSHAa0449 21 COG3495 COG3495, Uncharacterized protein conserved in bacteria Function unknown 77361279 Common motA flagellar motor protein PomA PSHAa2363 92 COG1291 MotA, Flagellar motor component Cell motility and secretion 77360101 Common - hypothetical protein PSHAa1158 87 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 77360535 Nonpathogen - hypothetical protein PSHAa1594 12 None None None 77361414 Common ftsZ Cell division protein ftsZ PSHAa2499 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 77360287 Common - hypothetical protein PSHAa1344 13 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 77359444 Common thiC thiamine biosynthesis protein ThiC PSHAa0480 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 77359926 Common - hypothetical protein PSHAa0980 90 COG0679 COG0679, Predicted permeases General function prediction only 77360200 Common - Na+/H+ antiporter PSHAa1257 121 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 77360656 Common - cell division protein with DNA segregation ATPase FtsK/SpoIIIE domain PSHAa1716 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 77360865 Common - hypothetical protein PSHAa1933 88 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 77361878 Common - alkaline phosphatase PSHAa2976 86 COG1785 PhoA, Alkaline phosphatase Inorganic ion transport and metabolism 77361858 Common - hypothetical protein PSHAa2956 10 None None None 77360844 Common - hypothetical protein PSHAa1906 20 COG3249 COG3249, Uncharacterized protein conserved in bacteria Function unknown 77359434 Common galE UDP-galactose 4-epimerase PSHAa0469 233 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 77361549 Common pdxA 4-hydroxythreonine-4-phosphate dehydrogenase,(4-(phosphohydroxy)-L-threonine dehydrogenase) PSHAa2634 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 77360149 Common - 23S rRNA pseudouridylate synthase PSHAa1206 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 77359584 Common - transpeptidase protein PSHAa0631 15 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 77360967 Common phhA phenylalanine 4-monooxygenase PSHAa2043 45 COG3186 COG3186, Phenylalanine-4-hydroxylase Amino acid transport and metabolism 77359289 Common secF preprotein translocase subunit SecF PSHAa0322 215 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 77361528 Common yfiQ acyl-CoA synthetase, NAD(P)-binding, ATP-binding PSHAa2613 152 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 77359074 Nonpathogen - hypothetical protein PSHAa0097 8 None None None 77360000 Common hemA glutamyl tRNA reductase PSHAa1057 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 77359329 Common - hypothetical protein PSHAa0363 66 COG2861 COG2861, Uncharacterized protein conserved in bacteria Function unknown 77361098 Common mgsA methylglyoxal synthase PSHAa2175 88 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 77361659 Common mutT 7,8-dihydro-8-oxoguanine-triphosphatase PSHAa2744 164 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 77361636 Common mrcA Murein polymerase, bifunctional murein transglycosylase (N-terminal) and transpeptidase (C-terminal); penicillin-binding protein PBP1A PSHAa2721 200 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 77359331 Common - protease PSHAa0365 185 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 77359868 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase PSHAa0921 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 77361697 Common pyrE orotate phosphoribosyltransferase PSHAa2787 142 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 77360716 Common - transcriptional regulator PSHAa1776 138 COG1802 GntR, Transcriptional regulators Transcription 77359322 Common ftsX cell division protein PSHAa0356 127 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 77360632 Common hflD hypothetical protein PSHAa1691 41 COG2915 COG2915, Uncharacterized protein involved in purine metabolism General function prediction only 77360280 Common - 23S rRNA m1G745 methyltransferase PSHAa1337 56 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 77361111 Common - hydrolase PSHAa2188 40 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 77360121 Common - L-arabinose/isopropyl-beta-D-thiogalactopyranoside export protein (MFS) PSHAa1178 152 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77360750 Common plsX fatty acid/phospholipid synthesis protein PSHAa1810 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 77361139 Common hrpB ATP-dependent helicase PSHAa2216 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 77360496 Common - hypothetical protein PSHAa1555 5 None None None 77360524 Common msrAA Peptide methionine sulfoxide reductase msrA 2 (Protein-methionine-S-oxide reductase 2) (Peptide Met(O) reductase 2) PSHAa1583 204 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 77360403 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase PSHAa1460 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77361178 Common hemL Glutamate-1-semialdehyde 2,1-aminomutase (GSA) (Glutamate-1-semialdehyde aminotransferase) PSHAa2255 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 77361437 Common - lipoprotein PSHAa2522 45 COG3107 LppC, Putative lipoprotein General function prediction only 77359968 Common dacA D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 5 PSHAa1022 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 77361917 Common trmE tRNA modification GTPase TrmE PSHAa3021 225 COG0486 ThdF, Predicted GTPase General function prediction only 77360853 Nonpathogen - hypothetical protein PSHAa1921 2 None None None 77361106 Nonpathogen - hypothetical protein PSHAa2183 1 None None None 77360304 Nonpathogen - hypothetical protein ; membrane-associated protein PSHAa1361 1 None None None 77359761 Common cheA chemotaxis protein PSHAa0812 153 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 77359028 Common - hypothetical protein PSHAa0050 81 COG3146 COG3146, Uncharacterized protein conserved in bacteria Function unknown 77361888 Common - ATP-binding protein PSHAa2986 42 COG0433 COG0433, Predicted ATPase General function prediction only 77359909 Common - hypothetical protein PSHAa0963 3 None None None 77359316 Common dnaG DNA primase PSHAa0350 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 77361513 Common - hypothetical protein PSHAa2598 206 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 77359613 Common serB phosphoserine phosphatase PSHAa0661 151 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 77360088 Common - two-component response regulator PSHAa1145 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77359899 Common - anti-sigma factor antagonist PSHAa0953 18 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 77359388 Nonpathogen - hypothetical protein PSHAa0422 1 None None None 77361910 Common atpB F0F1 ATP synthase subunit A PSHAa3014 155 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 77361871 Nonpathogen - hypothetical protein PSHAa2969 1 None None None 77359113 Common tesB acyl-CoA thioesterase II PSHAa0141 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 77360884 Common fadE acyl-CoA dehydrogenase PSHAa1952 147 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77360898 Common - hypothetical protein PSHAa1973 10 None None None 77360810 Common - TolA protein PSHAa1872 16 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 77360305 Common - hypothetical protein PSHAa1362 133 COG2860 COG2860, Predicted membrane protein Function unknown 77360078 Nonpathogen - hypothetical protein PSHAa1135 2 None None None 77360762 Common - transcriptional regulator PSHAa1822 96 COG0583 LysR, Transcriptional regulator Transcription 77359391 Nonpathogen - hypothetical protein PSHAa0425 1 None None None 77360757 Common - nucleoid-associated protein NdpA PSHAa1817 31 COG3081 COG3081, Nucleoid-associated protein General function prediction only 77359162 Common - hypothetical protein PSHAa0191 13 COG2841 COG2841, Uncharacterized protein conserved in bacteria Function unknown 77359805 Common - glutathione-regulated potassium-efflux system protein ( K(+)/H(+) antiporter) PSHAa0856 180 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 77360035 Nonpathogen - hypothetical protein PSHAa1092 1 None None None 77359637 Common ispF 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (MECPS) (MECDP-synthase) PSHAa0685 189 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 77359198 Common tufA elongation factor Tu PSHAa0227 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 77360832 Common - lipoprotein PSHAa1894 16 None None None 77361321 Common - hypothetical protein PSHAa2405 24 None None None 77361025 Nonpathogen - hypothetical protein PSHAa2101 1 None None None 77359700 Common thyA thymidylate synthase PSHAa0749 136 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 77359930 Common - hypothetical protein PSHAa0984 35 None None None 77359921 Common - hypothetical protein PSHAa0975 78 COG1556 COG1556, Uncharacterized conserved protein Function unknown 77360380 Common - hypothetical protein PSHAa1437 85 COG1262 COG1262, Uncharacterized conserved protein Function unknown 77361423 Common murF D-alanine:D-alanine-adding enzyme PSHAa2508 211 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 162139932 Common - hypothetical protein PSHAa0124 20 COG3112 COG3112, Uncharacterized protein conserved in bacteria Function unknown 77360027 Common - inner membrane protein PSHAa1084 9 None None None 77359877 Common - Type IV pilus biogenesis protein PSHAa0930 4 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 77360548 Common bioC desthiobiotin biosynthesis; reaction prior to pimeloyl CoA PSHAa1607 92 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 77359592 Common - hypothetical protein PSHAa0639 18 None None None 77360343 Common - hypothetical protein PSHAa1400 23 COG2866 COG2866, Predicted carboxypeptidase Amino acid transport and metabolism 77359367 Common - polysaccharide biosynthesis protein PSHAa0401 137 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 77361059 Common - transporter PSHAa2136 161 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 77359168 Common - hypothetical protein PSHAa0197 7 None None None 77361035 Nonpathogen - hypothetical protein PSHAa2112 1 None None None 77360184 Common - hypothetical protein PSHAa1241 34 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 77360621 Common - hypothetical protein PSHAa1680 2 None None None 77360959 Common tsf elongation factor Ts PSHAa2035 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 77361773 Common - cytochrome C oxidase assembly protein PSHAa2870 68 COG3175 COX11, Cytochrome oxidase assembly factor Posttranslational modification, protein turnover, chaperones 77359680 Common rseC regulator of sigma E (sigma 24) factor PSHAa0729 9 COG3086 RseC, Positive regulator of sigma E activity Signal transduction mechanisms 77361054 Common - acyl-CoA dehydrogenase protein PSHAa2131 150 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77360005 Common - inner membrane protein PSHAa1062 21 COG5505 COG5505, Predicted integral membrane protein Function unknown 77360612 Common - predicted exporter of the RND superfamily PSHAa1671 45 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 77360584 Common - hypothetical protein PSHAa1643 3 None None None 77359611 Common - hydrolase with metallo-dependent hydrolase domain PSHAa0659 231 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 77360299 Common - sugar transporter PSHAa1356 42 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 77361062 Common - aldehyde dehydrogenase PSHAa2139 219 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77361226 Common - hypothetical protein PSHAa2303 170 COG0344 COG0344, Predicted membrane protein Function unknown 77360327 Nonpathogen - transport protein PSHAa1384 1 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 77360230 Common hupA DNA-binding protein PSHAa1287 206 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 77361083 Nonpathogen - hypothetical protein PSHAa2160 1 None None None 77361560 Common slmA nucleoid occlusion protein PSHAa2645 63 COG1309 AcrR, Transcriptional regulator Transcription 77361795 Common leuC isopropylmalate isomerase large subunit PSHAa2892 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 77360455 Nonpathogen - hypothetical protein PSHAa1514 1 None None None 77360412 Common - hypothetical protein PSHAa1469 131 COG0730 COG0730, Predicted permeases General function prediction only 77359885 Common - hypothetical protein PSHAa0938 38 COG4764 COG4764, Uncharacterized protein conserved in bacteria Function unknown 77361173 Nonpathogen - hypothetical protein PSHAa2250 2 None None None 77360189 Common - hypothetical protein PSHAa1246 5 None None None 77360191 Common - transport protein PSHAa1248 54 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 77360873 Common - hypothetical protein PSHAa1941 11 None None None 77361614 Common - Mannose-sensitive agglutinin (MSHA) biogenesis protein MshI (pilus type IV)with frame shift PSHAa2699 10 None None None 77359467 Nonpathogen - hypothetical protein PSHAa0509 2 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 77359470 Common - hypothetical protein PSHAa0512 30 COG4731 COG4731, Uncharacterized protein conserved in bacteria Function unknown 77359568 Nonpathogen - calcium-binding protein PSHAa0615 3 None None None 77360732 Common - similar to Bacillus cereus hypothetical protein PSHAa1792 16 None None None 77361078 Common - protein W (OmpW) PSHAa2155 69 COG3047 OmpW, Outer membrane protein W Cell envelope biogenesis, outer membrane 77361682 Common - hypothetical protein PSHAa2767 78 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 77359240 Common hflK hypothetical protein PSHAa0273 203 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 77360170 Common dapB dihydrodipicolinate reductase PSHAa1227 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 77359084 Common - hypothetical protein PSHAa0107 61 COG2354 COG2354, Uncharacterized protein conserved in bacteria Function unknown 77360169 Common - Na+/H+ antiporter PSHAa1226 65 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 77360658 Common - Alanine dehydrogenase PSHAa1718 169 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 77361869 Common - transcriptional regulator PSHAa2967 128 COG1846 MarR, Transcriptional regulators Transcription 77360040 Nonpathogen - hypothetical protein PSHAa1097 1 None None None 77361385 Nonpathogen - hypothetical protein PSHAa2470 1 None None None 77359655 Common - inner membrane protein PSHAa0703 23 COG4267 COG4267, Predicted membrane protein Function unknown 77361860 Common - multidrug resistance protein PSHAa2958 78 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 77360577 Common - hydrolase PSHAa1636 181 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77360289 Common - proton/glutamate symporter PSHAa1346 164 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 77359749 Common fliN flagellar motor switch protein PSHAa0800 122 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 77360449 Common - hypothetical protein PSHAa1508 18 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 77359221 Common trmA tRNA (uracil-5-)-methyltransferase PSHAa0250 167 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 77360137 Common dksAB DksA-type zinc finger protein PSHAa1194 5 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 77361318 Common gabD succinate-semialdehyde dehydrogenase PSHAa2402 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77360770 Common - transcriptional regulator with periplasmic binding protein domain (LysR) PSHAa1830 168 COG0583 LysR, Transcriptional regulator Transcription 77361034 Common - hypothetical protein PSHAa2111 7 COG2929 COG2929, Uncharacterized protein conserved in bacteria Function unknown 77359768 Common - hypothetical protein PSHAa0819 12 None None None 77360936 Nonpathogen - hypothetical protein PSHAa2012 1 None None None 77359191 Common rplJ 50S ribosomal protein L10 PSHAa0220 197 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 77360332 Common lolD transport protein of inner membrane lipoproteins (ABC superfamily, ATP-binding) PSHAa1389 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 77361473 Common - hypothetical protein PSHAa2558 87 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 77360920 Common - conserved protein of unknown function; enzyme PSHAa1996 186 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 77360421 Nonpathogen - hypothetical protein PSHAa1478 2 None None None 77360794 Common - hydrolase PSHAa1854 69 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 77360431 Common yhdH dehydrogenase, NAD(P)-binding domain and GroES-like domain PSHAa1488 165 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 77361063 Common tesA TesA protein PSHAa2140 109 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 77360807 Common - periplasmic protein contains a protein prenylyltransferase domain PSHAa1869 91 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 77359711 Common - hypothetical protein PSHAa0761 11 None None None 77359203 Common exeD general secretion pathway protein D PSHAa0232 142 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 77359216 Nonpathogen - hypothetical protein PSHAa0245 1 None None None 77360415 Nonpathogen - hypothetical protein PSHAa1472 2 None None None 77360420 Common - probable nitrite reductase PSHAa1477 105 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 77361619 Common - conserved protein of unknown function (lipoprotein) PSHAa2704 35 None None None 77360162 Nonpathogen - hypothetical protein PSHAa1219 1 None None None 77361811 Common - hypothetical protein PSHAa2909 31 COG3089 COG3089, Uncharacterized protein conserved in bacteria Function unknown 77360954 Common dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase PSHAa2030 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 77361498 Common - hypothetical protein PSHAa2583 23 COG3076 COG3076, Uncharacterized protein conserved in bacteria Function unknown 77361311 Common - two-component response regulator PSHAa2395 217 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77360573 Common BckdhA 2-oxoisovalerate dehydrogenase alpha subunit (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDH E1-alpha) (BCKDE1A) PSHAa1632 157 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 77359050 Common folE GTP cyclohydrolase I PSHAa0073 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 77361783 Common hmp two-domains flavohemoprotein: one is a heme-containing oxygen binding domain in the N-terminal region and the other is an FAD-containing reductase domain found in the C-terminal region PSHAa2880 129 COG1017 Hmp, Hemoglobin-like flavoprotein Energy production and conversion 77359986 Common - hypothetical protein PSHAa1040 28 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 77361890 Common - hypothetical protein PSHAa2988 10 COG1159 Era, GTPase General function prediction only 77361599 Common mshQ Mannose-sensitive agglutinin (MSHA) biogenesis protein MshQ (pilus type IV) PSHAa2684 18 None None None 77360728 Nonpathogen - hypothetical protein PSHAa1788 1 COG1480 COG1480, Predicted membrane-associated HD superfamily hydrolase General function prediction only 77361046 Nonpathogen - hypothetical protein PSHAa2123 3 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 77360047 Common rsxB electron transport complex protein RnfB PSHAa1104 127 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 77360916 Common - conserved protein of unknown functions similar to YfcA PSHAa1992 124 COG0730 COG0730, Predicted permeases General function prediction only 77361564 Common - Serine protease precursor PSHAa2649 124 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 77359069 Common dapF diaminopimelate epimerase PSHAa0092 203 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 77360030 Common msrB Peptide methionine-R-sulfoxide reductase, MsrB protein (PilB protein) PSHAa1087 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 77360836 Common dagA Na(+)-linked D-alanine glycine permease PSHAa1898 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 77361264 Nonpathogen - hypothetical protein PSHAa2347 1 None None None 77359816 Nonpathogen - hypothetical protein PSHAa0867 1 None None None 77359093 Common - hypothetical protein PSHAa0121 48 COG1444 COG1444, Predicted P-loop ATPase fused to an acetyltransferase General function prediction only 77359640 Common pcm L-isoaspartate protein carboxylmethyltransferase type II PSHAa0688 156 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 77359038 Nonpathogen - hypothetical protein PSHAa0061 1 None None None 77361502 Common parE DNA topoisomerase IV subunit B PSHAa2587 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 77359841 Common - electron acceptor reductase/NADH oxidase, FAD binding, iron-sulfur cluster binding site PSHAa0892 188 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 77359184 Common cysG siroheme synthase PSHAa0213 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 77361493 Common - hypothetical protein PSHAa2578 39 COG4067 COG4067, Uncharacterized protein conserved in archaea Posttranslational modification, protein turnover, chaperones 77361126 Common - hypothetical protein PSHAa2203 162 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 77361145 Common - B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase (C terminal) PSHAa2222 169 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 77360116 Common - hypothetical protein PSHAa1173 108 COG0327 COG0327, Uncharacterized conserved protein Function unknown 77360505 Common - hypothetical protein PSHAa1564 70 COG2968 COG2968, Uncharacterized conserved protein Function unknown 77359238 Common hfq polyA-binding protein PSHAa0271 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 77360628 Common - anaerobic sulfite reductase subunit gamma PSHAa1687 60 COG2920 DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit Inorganic ion transport and metabolism 77360702 Common ureG urease accessory protein PSHAa1762 141 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 77360665 Common clpS modulator of ClpA substrate specificity PSHAa1725 119 COG2127 COG2127, Uncharacterized conserved protein Function unknown 77359665 Common - mechanosensitive channel protein PSHAa0714 146 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 77361404 Common - glutathione S-transferase enzyme with thioredoxin-like domain PSHAa2489 34 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 77361011 Nonpathogen - hypothetical protein PSHAa2087 1 None None None 77360685 Common - ketodeoxygluconokinase PSHAa1745 113 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 77361595 Common mreD rod shape-determining protein PSHAa2680 63 COG2891 MreD, Cell shape-determining protein Cell envelope biogenesis, outer membrane 77359373 Common - hypothetical protein PSHAa0407 109 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 77359697 Common ptsP phosphoenolpyruvate-protein phosphotransferase ptsP (Phosphotransferase system, enzyme I) (Enzyme I-Ntr) PSHAa0746 235 COG3605 PtsP, Signal transduction protein containing GAF and PtsI domains Signal transduction mechanisms 77359231 Common aroQ 3-dehydroquinate dehydratase PSHAa0264 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 77359271 Common - cation efflux system protein PSHAa0304 158 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 77359059 Common - exporter protein PSHAa0082 129 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 77361665 Common - hypothetical protein PSHAa2750 14 None None None 77359032 Common - hypothetical protein PSHAa0054 4 None None None 77359540 Common - Sensory box histidine kinase/response regulator PSHAa0585 227 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 77361446 Common rpsI 30S ribosomal subunit protein S9 PSHAa2531 248 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 77361570 Common rpmA 50S ribosomal protein L27 PSHAa2655 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 77359021 Common - hypothetical protein PSHAa0043 4 None None None 77360067 Nonpathogen - hypothetical protein PSHAa1124 1 None None None 77361546 Common - hypothetical protein PSHAa2631 90 COG3178 COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases General function prediction only 77358996 Common - GTP-binding protein PSHAa0014 132 COG1739 COG1739, Uncharacterized conserved protein Function unknown 77359914 Common - hypothetical protein PSHAa0968 39 COG2315 MmcQ, Uncharacterized protein conserved in bacteria Function unknown 77360694 Common - transcriptional regulator with periplasmic binding protein domain (LysR) PSHAa1754 171 COG0583 LysR, Transcriptional regulator Transcription 77361789 Common - oxidoreductase PSHAa2886 144 COG0431 COG0431, Predicted flavoprotein General function prediction only 77361877 Common - hypothetical protein ; secreted protein PSHAa2975 4 None None None 77359381 Common - transposase PSHAa0415 37 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 77361676 Common - GGDEF domain protein PSHAa2761 179 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 77361286 Common nusB transcription termination factor PSHAa2370 200 COG0781 NusB, Transcription termination factor Transcription 77360555 Common - ABC-type transport system, ATPase component PSHAa1614 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 77359609 Common argS arginyl-tRNA synthetase PSHAa0656 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 77359991 Common ybeZ PhoH-like protein PSHAa1045 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 77359127 Common cysI sulfite reductase subunit beta PSHAa0155 147 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 77359154 Common - hypothetical protein PSHAa0183 144 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 77359120 Common rpsS 30S ribosomal protein S19 PSHAa0148 246 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 77359604 Common - transcriptional regulator PSHAa0651 73 COG1309 AcrR, Transcriptional regulator Transcription 77360479 Nonpathogen - hypothetical protein PSHAa1538 1 None None None 77359456 Common zur Zinc uptake regulation protein PSHAa0493 139 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 77360815 Common ruvC Holliday junction nuclease PSHAa1877 195 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 77361169 Common - lipoprotein PSHAa2246 3 COG3056 COG3056, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 77361018 Common hsdM type I restriction-modification system, M subunit; N-6 Adenine-specific DNA methylase PSHAa2094 158 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 77360093 Common CheB Response regulator CheB (receptor modification enzyme, protein-glutamate methylesterase) PSHAa1150 218 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 77360079 Nonpathogen - hypothetical protein PSHAa1136 1 None None None 77361640 Common maeB NADP-dependent malic enzyme (NADP-dependent malic oxidoreductase (N-terminal); phosphotransacetylase (C-terminal)) PSHAa2725 202 COG0281 SfcA, Malic enzyme Energy production and conversion 77359362 Common mscS mechanosensitive channel protein PSHAa0396 203 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 77361273 Common - hypothetical protein PSHAa2357 4 None None None 77359875 Common pilE fimbrial protein precursor PSHAa0928 10 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 77360896 Common - hypothetical protein PSHAa1971 32 COG3098 COG3098, Uncharacterized protein conserved in bacteria Function unknown 77360072 Common - transport protein (ABC superfamily, atp_bind and membrane) PSHAa1129 63 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 77359718 Nonpathogen - hypothetical protein PSHAa0768 1 None None None 77360662 Common - arginyl-tRNA-protein transferase PSHAa1722 85 COG2935 COG2935, Putative arginyl-tRNA:protein arginylyltransferase Posttranslational modification, protein turnover, chaperones 77361534 Common - 2-hydroxyacid dehydrogenase protein PSHAa2619 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 77361141 Common - hypothetical protein PSHAa2218 57 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 77360130 Common - hypothetical protein PSHAa1187 18 None None None 77360155 Common - hypothetical protein PSHAa1212 71 COG2719 SpoVR, Uncharacterized conserved protein Function unknown 77361753 Common ompR osmolarity response regulator PSHAa2850 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77361427 Common mraW S-adenosyl-methyltransferase MraW PSHAa2512 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 77359852 Common - dioxygenase PSHAa0904 116 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 77360448 Common - hypothetical protein PSHAa1507 3 None None None 77359425 Common - hypothetical protein PSHAa0460 3 None None None 77359638 Common truD tRNA pseudouridine synthase D (Pseudouridylate synthase) (Uracil hydrolyase) PSHAa0686 86 COG0585 COG0585, Uncharacterized conserved protein Function unknown 77361911 Common atpI membrane-bound ATP synthase subunit, F1-F0-type proton-ATPase PSHAa3015 30 COG3312 AtpI, F0F1-type ATP synthase, subunit I Energy production and conversion 77360124 Common metR Transcriptional activator MetR PSHAa1181 184 COG0583 LysR, Transcriptional regulator Transcription 77361168 Common rsmD ribosomal RNA small subunit methyltransferase D PSHAa2245 96 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 77360934 Common - Glutathione-regulated potassium-efflux system protein KefB PSHAa2010 206 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 77361849 Common - TonB-dependent receptor PSHAa2947 111 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 77359295 Nonpathogen - hypothetical protein PSHAa0328 1 None None None 77360541 Common - cold-shock DNA-binding domain PSHAa1600 24 COG1278 CspC, Cold shock proteins Transcription 77359563 Common hpt hypoxanthine-guanine phosphoribosyltransferase PSHAa0609 40 COG2236 COG2236, Predicted phosphoribosyltransferases General function prediction only 77361803 Common fkpA periplasmic peptidyl-prolyl cis-trans isomerase PSHAa2901 137 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 77359008 Common smg hypothetical protein PSHAa0026 39 COG2922 Smg, Uncharacterized protein conserved in bacteria Function unknown 77359398 Nonpathogen - hypothetical protein PSHAa0432 1 None None None 77360709 Common galK galactokinase PSHAa1769 85 COG0153 GalK, Galactokinase Carbohydrate transport and metabolism 77360528 Nonpathogen - hypothetical protein PSHAa1587 1 None None None 77361365 Common - conserved protein of unknown function; glyoxalase/bleomycin resistance protein/dioxygenase domain PSHAa2449 56 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 77359396 Common - C4-dicarboxylate anaerobic carrier PSHAa0430 45 COG1288 COG1288, Predicted membrane protein Function unknown 77361535 Common - two-component response regulator PSHAa2620 224 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 77360851 Common - hypothetical protein PSHAa1919 4 None None None 77361882 Common cspE Cold shock-like protein cspE, RNA chaperone, transcription antiterminator, affects expression of rpoS and uspA PSHAa2980 179 COG1278 CspC, Cold shock proteins Transcription 77359224 Common - hypothetical protein PSHAa0253 64 COG0724 COG0724, RNA-binding proteins (RRM domain) General function prediction only 77361001 Nonpathogen - hypothetical protein PSHAa2077 1 None None None 77361508 Common lpxL Lipid A biosynthesis lauroyl acyltransferase PSHAa2593 100 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 77361103 Common - TonB-dependent receptor PSHAa2180 90 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 77360821 Common - hypothetical protein PSHAa1883 15 None None None 77360513 Common purK phosphoribosylaminoimidazole carboxylase ATPase subunit PSHAa1572 193 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 77361861 Common - oxidoreductase PSHAa2959 115 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 77361208 Nonpathogen - hypothetical protein PSHAa2285 1 None None None 77359006 Common - hypothetical protein PSHAa0024 46 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 77359573 Common - sensory histidine kinase in regulatory system PSHAa0620 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77359364 Common - polysaccharide export protein PSHAa0398 115 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 77360468 Common - hypothetical protein PSHAa1527 2 None None None 77360015 Common - glycine betaine transporter PSHAa1072 95 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 77361658 Common secA preprotein translocase subunit SecA PSHAa2743 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 77360741 Common pilZ type 4 fimbrial biogenesis protein PILZ PSHAa1801 33 COG3215 PilZ, Tfp pilus assembly protein PilZ Cell motility and secretion / Intracellular trafficking and secretion 77359863 Common mviN virulence factor mviN PSHAa0916 201 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 77360498 Common - hypothetical protein PSHAa1557 3 None None None 77359447 Common thiG thiazole synthase PSHAa0483 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 77359825 Common - hypothetical protein PSHAa0876 111 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 77360397 Common atoB acetyl-CoA acetyltransferase with thiolase domain PSHAa1454 185 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 77361815 Common birA biotin--protein ligase PSHAa2913 228 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 77360148 Common - hypothetical protein PSHAa1205 8 None None None 77359798 Common ilvC ketol-acid reductoisomerase PSHAa0849 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 77359931 Common - hypothetical protein; signal peptide PSHAa0985 2 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 77359580 Common - sensor histidine kinase PSHAa0627 211 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77359723 Common flgF flagellar biosynthesis; cell-proximal portion of basal-body rod PSHAa0773 120 COG4787 FlgF, Flagellar basal body rod protein Cell motility and secretion 77361469 Common - hypothetical protein PSHAa2554 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 77361581 Common fdx [2Fe-2S] ferredoxin, electron carrier protein, involved in assembly of Fe-S clusters PSHAa2666 81 COG0633 Fdx, Ferredoxin Energy production and conversion 77360723 Common wcaJ UDP-glucose lipid carrier transferase PSHAa1783 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 77361462 Common kdsC 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase PSHAa2547 105 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 77360229 Common - sodium-dependent transporter PSHAa1286 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 77361526 Nonpathogen - hypothetical protein PSHAa2611 1 None None None 77361497 Common - hypothetical protein PSHAa2582 2 None None None 77360307 Common - glucokinase PSHAa1364 91 COG0837 Glk, Glucokinase Carbohydrate transport and metabolism 77359771 Common ccmA heme exporter protein A, ABC superfamily (Cytochrome c-type biogenesis ATP-binding protein ccmA) PSHAa0822 249 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 77359512 Common - sensory box histidine kinase/response regulator PSHAa0556 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77359760 Common cheZ chemotaxis protein PSHAa0811 41 COG3143 CheZ, Chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77361851 Common - sensor protein PSHAa2949 201 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 77360752 Common - hypothetical protein PSHAa1812 55 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 77361511 Common - hypothetical protein PSHAa2596 4 None None None 77360748 Common fabG 3-oxoacyl-[acyl-carrier-protein] reductase PSHAa1808 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77360484 Nonpathogen - hypothetical protein PSHAa1543 1 None None None 77360285 Common rluB pseudouridine synthase (makes pseudouridine2605 in 23 S RNA) PSHAa1342 205 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 77359301 Nonpathogen - hypothetical protein PSHAa0334 17 None None None 77361057 Common - AMP-binding enzyme PSHAa2134 222 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 77360882 Common - hypothetical protein PSHAa1950 41 COG4125 COG4125, Predicted membrane protein Function unknown 77359311 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PSHAa0345 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 77359621 Nonpathogen - hypothetical protein PSHAa0669 1 None None None 77359649 Nonpathogen - hypothetical protein PSHAa0697 1 None None None 77360643 Common - hypothetical protein PSHAa1702 13 COG2374 COG2374, Predicted extracellular nuclease General function prediction only 77360889 Common rnhA RNase HI, degrades RNA of DNA-RNA hybrids PSHAa1964 177 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 77361631 Common pilQ type IV pilus biogenesis protein PilQ (cytoplasmic ATPase) PSHAa2716 143 COG4796 HofQ, Type II secretory pathway, component HofQ Intracellular trafficking and secretion 77360713 Common acnA aconitate hydratase PSHAa1773 222 COG1048 AcnA, Aconitase A Energy production and conversion 77359433 Common - ATPase PSHAa0468 98 COG1485 COG1485, Predicted ATPase General function prediction only 77360613 Common - hypothetical protein PSHAa1672 36 COG4447 COG4447, Uncharacterized protein related to plant photosystem II stability/assembly factor General function prediction only 77361116 Nonpathogen - hypothetical protein PSHAa2193 1 None None None 77361324 Common - transcriptional regulator (AraC/XylS) PSHAa2408 73 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77360956 Common ispU undecaprenyl pyrophosphate synthetase (UPP synthetase) (Di-trans-poly-cis-decaprenylcistransferase) (Undecaprenyl diphosphate synthase) (UDS) PSHAa2032 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 77360366 Common aroA 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) PSHAa1423 230 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 77359042 Common - hypothetical protein PSHAa0065 47 COG3658 COG3658, Cytochrome b Energy production and conversion 77359846 Common - nonspecific lipid-transfer protein PSHAa0897 90 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 77361588 Common - tRNA/rRNA methyltransferase PSHAa2673 155 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 77359244 Common - sodium/hydrogen antiporter PSHAa0277 113 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 77359095 Common - hypothetical protein PSHAa0123 6 None None None 77360246 Common icd isocitrate dehydrogenase, specific for NADP+ PSHAa1303 222 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 77360581 Nonpathogen - hypothetical protein PSHAa1640 1 None None None 77360014 Nonpathogen - hypothetical protein PSHAa1071 1 None None None 77359906 Common - hypothetical protein PSHAa0960 32 None None None 77359884 Common gshA glutamate--cysteine ligase (Gamma-glutamylcysteine synthetase) (Gamma-ECS) (GCS) PSHAa0937 58 COG2918 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 77359695 Nonpathogen - hypothetical protein PSHAa0744 1 None None None 77359508 Common rsmC ribosomal RNA small subunit methyltransferase C PSHAa0552 105 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 77360454 Nonpathogen - bacteriophage protein PSHAa1513 2 None None None 77361008 Common gltS glutamate transport protein (GltS) PSHAa2084 51 COG0786 GltS, Na+/glutamate symporter Amino acid transport and metabolism 77360846 Common pgsA CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (Phosphatidylglycerophosphate synthase) (PGP synthase) PSHAa1914 203 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 77360906 Common - hypothetical protein PSHAa1982 108 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 77361726 Common - hypothetical protein PSHAa2822 4 None None None 77361489 Common - hypothetical protein PSHAa2574 11 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 77359226 Common groEL chaperonin GroEL PSHAa0259 246 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 77360981 Common - hypothetical protein PSHAa2057 15 None None None 77361158 Common apbE lipoprotein PSHAa2235 134 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 77359350 Common ppdD prepilin peptidase dependent protein D PSHAa0384 15 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 77360346 Common - Sulfate permease protein PSHAa1403 161 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 77360048 Common rsxA Electron transport complex protein rnfA, inner membrane protein PSHAa1105 76 COG4657 RnfA, Predicted NADH:ubiquinone oxidoreductase, subunit RnfA Energy production and conversion 77359417 Common - transcriptional regulator PSHAa0452 5 None None None 77360677 Common - catalase PSHAa1737 127 COG0753 KatE, Catalase Inorganic ion transport and metabolism 77360965 Common betT high-affinity choline transport protein PSHAa2041 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 77361699 Common yicC hypothetical protein PSHAa2789 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 77359320 Common ftsY cell division transporter substrate-binding protein PSHAa0354 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 77361435 Common - mechanosensitive channel protein PSHAa2520 202 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 77359972 Common - hypothetical protein PSHAa1026 163 COG1576 COG1576, Uncharacterized conserved protein Function unknown 77359843 Common - 3-ketoacyl-(ACP) reductase PSHAa0894 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77359327 Common prlC oligopeptidase A PSHAa0361 123 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 77359488 Common recX regulatory protein, inhibitor of RecA recombinase and coprotease activities PSHAa0531 67 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 77360654 Common rarA recombination factor protein RarA PSHAa1714 234 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 77361029 Common - RepA PSHAa2105 24 COG5527 COG5527, Protein involved in initiation of plasmid replication DNA replication, recombination, and repair 77359479 Common - hypothetical protein PSHAa0522 137 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 77360550 Common bioB biotin synthase; contains an iron-sulfur cluster and PLP PSHAa1609 185 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 77361319 Common - hypothetical protein PSHAa2403 24 COG3021 COG3021, Uncharacterized protein conserved in bacteria Function unknown 77361634 Common pilN Type IV pilus biogenesis protein PilN PSHAa2719 42 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 77359200 Common hslO Hsp33-like chaperonin PSHAa0229 137 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 77361364 Common - endo alpha-1,4 polygalactosaminidase precusor PSHAa2448 19 COG3868 COG3868, Uncharacterized conserved protein Function unknown 77359214 Nonpathogen - hypothetical protein PSHAa0243 1 None None None 77361459 Common - transport protein (ABC superfamily, atp-binding) PSHAa2544 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 77359068 Common - hypothetical protein PSHAa0091 19 COG3159 COG3159, Uncharacterized protein conserved in bacteria Function unknown 77360927 Nonpathogen - hypothetical protein PSHAa2003 1 None None None 77361179 Common mrcB Murein polymerase, bifunctional murein transglycosylase and transpeptidase; penicillin-binding protein PBP1B; dimeric PSHAa2256 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 77359382 Common - transposase PSHAa0416 68 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 77361837 Common hemB delta-aminolevulinic acid dehydratase PSHAa2935 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 77360341 Common rpmI 50S ribosomal subunit protein A PSHAa1398 128 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 77360588 Common kgd alpha-ketoglutarate decarboxylase PSHAa1647 147 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 77360946 Common cydC cysteine transport (export) protein (ABC superfamily, membrane (N-terminal), atp_bind (C-terminal)) PSHAa2022 249 COG4987 CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 77360596 Common - SufE protein PSHAa1655 91 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 77361749 Common speA arginine decarboxylase PSHAa2846 132 COG1166 SpeA, Arginine decarboxylase (spermidine biosynthesis) Amino acid transport and metabolism 77359677 Common rpoE RNA polymerase sigma factor RpoE PSHAa0726 171 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 77360559 Common etfB Electron transfer flavoprotein beta-subunit (Beta-ETF) (Electron transfer flavoprotein small subunit) (ETFSS) PSHAa1618 153 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 77359173 Common - ribosome protein acetyltransferase PSHAa0202 19 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 77360337 Common - acyl-CoA synthetase PSHAa1394 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 77359656 Common - hypothetical protein PSHAa0704 161 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 77361071 Common - enzyme ; class II aldolase/adducin, N-terminal PSHAa2148 132 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 77359115 Common rpsJ 30S ribosomal subunit protein S10 PSHAa0143 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 77361744 Common - ABC-type multidrug transport system, ATPase and permease component PSHAa2841 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 77360992 Common - TRNA-(MS[2]IO[6]A)-hydroxylase PSHAa2068 40 COG4445 MiaE, Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 77360265 Nonpathogen - hypothetical protein PSHAa1322 1 None None None 77359106 Common - hypothetical protein PSHAa0134 171 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 77360410 Common - hypothetical protein PSHAa1467 2 None None None 77359207 Common gspH general secretion pathway protein H PSHAa0236 8 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 77360351 Common ansA cytoplasmic asparaginase I PSHAa1408 138 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 77359938 Common ibpB small heat shock protein PSHAa0992 67 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 77360563 Common - hypothetical protein PSHAa1622 74 COG1720 COG1720, Uncharacterized conserved protein Function unknown 77359958 Common - hypothetical protein PSHAa1012 15 COG4633 COG4633, Uncharacterized protein conserved in bacteria Function unknown 77359134 Nonpathogen - hypothetical protein PSHAa0162 5 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 77361255 Nonpathogen - hypothetical protein PSHAa2332 1 None None None 77360777 Common - hypothetical protein PSHAa1837 7 None None None 77360276 Common - PTS system protein (partial match) PSHAa1333 44 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 77359702 Nonpathogen - hypothetical protein PSHAa0751 2 None None None 77361109 Common madN hypothetical protein PSHAa2186 23 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 77360253 Common - signal peptidase I protein PSHAa1310 206 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 77360549 Common bioF 8-amino-7-oxononanoate synthase (7-keto-8-aminopelargonic acid synthetase) PSHAa1608 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 77360472 Nonpathogen - hypothetical protein PSHAa1531 1 None None None 77359490 Common lysC Aspartokinase PSHAa0533 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 77360202 Common - transport protein of the major facilitator PSHAa1259 58 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77361086 Common - cellulose synthase regulator protein PSHAa2163 20 None None None 77361197 Common msrAB protein-methionine-S-oxide reductase (Peptide Met(O) reductase) PSHAa2274 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 77360222 Common - integral membrane transport protein PSHAa1279 164 COG0628 PerM, Predicted permease General function prediction only 77361348 Common - hypothetical protein PSHAa2432 10 None None None 77359178 Common - hypothetical protein PSHAa0207 37 COG4928 COG4928, Predicted P-loop ATPase General function prediction only 77361484 Common - hypothetical protein PSHAa2569 23 COG3085 COG3085, Uncharacterized protein conserved in bacteria Function unknown 77360862 Common rhlE ATP-dependent RNA helicase PSHAa1930 235 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 77359061 Common - hypothetical protein PSHAa0084 27 COG3686 COG3686, Predicted membrane protein Function unknown 77360787 Common - Cation transport ATPase, E1-E2 PSHAa1847 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 77359457 Common dusA tRNA-dihydrouridine synthase A PSHAa0499 209 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 77361899 Common cobS cobalamin 5'-phosphate synthase PSHAa2998 37 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 77360278 Nonpathogen - hypothetical protein PSHAa1335 1 None None None 77360972 Common pspB phage shock protein B PSHAa2048 23 None None None 77359389 Nonpathogen - phage integrase PSHAa0423 1 None None None 77361268 Nonpathogen - hypothetical protein PSHAa2352 1 None None None 77361876 Common - protein TrkB involved in potassium or sodium transport (efflux) PSHAa2974 204 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 77361030 Nonpathogen - hypothetical protein PSHAa2106 1 None None None 77361419 Common murG UDP-N-acetylglucosamine:N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase PSHAa2504 208 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 77361540 Common - hypothetical protein PSHAa2625 9 COG3668 ParE, Plasmid stabilization system protein General function prediction only 77361295 Common thrA bifunctional aspartokinase I/homeserine dehydrogenase I PSHAa2379 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 77359544 Common - DNA polymerase PSHAa0589 100 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 77360606 Common uup ABC transporter ATP-binding protein PSHAa1665 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 77361301 Common - HIT hydrolase PSHAa2385 68 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 77360891 Common gloB hydroxyacylglutathione hydrolase with metallo-hydrolase/oxidoreductase domain PSHAa1966 197 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 77360325 Common - beta-ketoacyl synthase PSHAa1382 206 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 77361922 Common rpmH 50S ribosomal protein L34 PSHAa3026 190 COG0230 RpmH, Ribosomal protein L34 Translation, ribosomal structure and biogenesis 77360674 Common ribC riboflavin synthase subunit alpha PSHAa1734 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 77361343 Nonpathogen - hypothetical protein PSHAa2427 1 None None None 77360680 Common - TonB-dependent receptor PSHAa1740 21 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 77360086 Common iaaA L-asparaginase PSHAa1143 84 COG1446 COG1446, Asparaginase Amino acid transport and metabolism 77361235 Common - flagellar basal body-associated protein FliL-like protein PSHAa2312 12 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 77360557 Common asnC asparaginyl-tRNA synthetase PSHAa1616 237 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 77360618 Common - Na+/H+ antiporter NnaC PSHAa1677 60 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 77360077 Common - prenylyltransferase domain and metalloprotease (zincins), catalytic domain PSHAa1134 128 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 77360219 Common - hypothetical protein PSHAa1276 6 None None None 77361775 Common - Cytochrome c oxidase, subunit II (partial) PSHAa2872 158 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 77360828 Common helD helicase IV PSHAa1890 218 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 77359587 Common - Glutaredoxin PSHAa0634 22 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 77360255 Common - hypothetical protein PSHAa1312 4 None None None 77360529 Common - transcriptional regulator with homeodomain-like DNA binding domain (AraC/XylS) PSHAa1588 132 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 77361298 Common - signal transduction protein PSHAa2382 52 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 77360507 Common - gamma-glutamyltranspeptidase PSHAa1566 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 77360611 Common - glutamate dehydrogenase PSHAa1670 77 COG2902 COG2902, NAD-specific glutamate dehydrogenase Amino acid transport and metabolism 77360660 Common trxB thioredoxin reductase, FAD/NAD(P)-binding PSHAa1720 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 77360818 Common apeA multifunctional: Acyl-CoA thioesterase I precursor (Protease I) (Lysophospholipase L1) (Lecithinase B) PSHAa1880 100 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 77361572 Common ispB Octaprenyl-diphosphate synthase (Octaprenyl pyrophosphate synthetase)(OPP synthetase) PSHAa2657 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 77359558 Common pcnB poly(A) polymerase I PSHAa0604 213 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 77359591 Nonpathogen - hypothetical protein PSHAa0638 1 None None None 77361160 Common nqrE Na(+)-translocating NADH-quinone reductase subunit E PSHAa2237 76 COG2209 NqrE, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE Energy production and conversion 77361107 Common dcp Peptidyl-dipeptidase dcp (Dipeptidyl carboxypeptidase) PSHAa2184 124 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 77361781 Common cbpA curved DNA-binding protein, co-chaperone of DnaK (Hsp40) PSHAa2878 232 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 77359276 Common pstC phosphate ABC transporter permease protein PSHAa0309 219 COG4590 COG4590, ABC-type uncharacterized transport system, permease component General function prediction only 77360707 Common galM galactose-1-epimerase (mutarotase) PSHAa1767 92 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 77359707 Common - hypothetical protein PSHAa0756 7 COG5616 COG5616, Predicted integral membrane protein Function unknown 77360987 Common tig trigger factor PSHAa2063 216 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 77361271 Common - nucleoside phosphorylase PSHAa2355 14 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 77359105 Common - hypothetical protein PSHAa0133 218 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 77360157 Common - conserved protein of unknown function, nucleotide triphosphate hydrolase domain PSHAa1214 69 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 77360570 Common - hypothetical protein PSHAa1629 9 None None None 77360378 Common - DNA polymerase III subunit epsilon PSHAa1435 120 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 77359503 Common mtnN 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; MtnN PSHAa0547 101 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 77359834 Common - acyl-CoA dehydrogenase protein PSHAa0885 117 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77360595 Common csdA Cysteine sulfinate desulfinase (CSD) PSHAa1654 237 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 77359605 Nonpathogen - hypothetical protein PSHAa0652 1 None None None 77361288 Common ribB 3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP synthase) PSHAa2372 227 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 77361862 Nonpathogen - inner membrane protein PSHAa2960 1 None None None 77361756 Common - hypothetical protein PSHAa2853 15 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 77361243 Common - glycosyl transferase PSHAa2320 156 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 77360334 Common - hypothetical protein PSHAa1391 31 COG4807 COG4807, Uncharacterized protein conserved in bacteria Function unknown 77359997 Common prs ribose-phosphate pyrophosphokinase PSHAa1054 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 77359334 Common - glutaredoxin PSHAa0368 125 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 77359984 Common - protease PSHAa1038 148 COG4946 COG4946, Uncharacterized protein related to the periplasmic component of the Tol biopolymer transport system Function unknown 77361617 Common - cytochrome-c peroxidase PSHAa2702 93 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 77361166 Common bolA regulator protein PSHAa2243 104 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 77360139 Nonpathogen - hypothetical protein PSHAa1196 1 None None None 77360113 Common - hypothetical protein PSHAa1170 58 COG3228 COG3228, Uncharacterized protein conserved in bacteria Function unknown 77361378 Common mdtI multidrug transport protein (SmR superfamily) PSHAa2462 111 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 77361701 Common rpoZ DNA-directed RNA polymerase subunit omega PSHAa2791 108 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 77359152 Common - hypothetical protein PSHAa0181 42 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 77360737 Common - hypothetical protein PSHAa1797 9 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 77361801 Common hemE uroporphyrinogen decarboxylase PSHAa2899 182 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 77359602 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein PSHAa0649 239 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 77360150 Common htpG heat shock protein 90 PSHAa1207 150 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 77359967 Common - hypothetical protein PSHAa1021 27 COG2921 COG2921, Uncharacterized conserved protein Function unknown 77359989 Common corC magnesium and cobalt efflux protein corC PSHAa1043 216 COG4535 CorC, Putative Mg2+ and Co2+ transporter CorC Inorganic ion transport and metabolism 77360446 Common - hypothetical protein PSHAa1505 28 COG2369 COG2369, Uncharacterized protein, homolog of phage Mu protein gp30 Function unknown 77359034 Nonpathogen - RNA binding protein PSHAa0056 1 None None None 77359253 Common - hypothetical protein PSHAa0286 70 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 77361417 Common ddlB D-alanine-D-alanine ligase B, affects cell division PSHAa2502 215 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 77360635 Common - hypothetical protein PSHAa1694 45 COG2153 ElaA, Predicted acyltransferase General function prediction only 77359258 Common - glucose dehydrogenase PSHAa0291 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77359713 Common flgN flagellar biosynthesis chaperone PSHAa0763 6 COG3418 COG3418, Flagellar biosynthesis/type III secretory pathway chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 77359294 Common - hypothetical protein PSHAa0327 8 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 77359543 Common - inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) PSHAa0588 187 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 77359598 Common cysE serine acetyltransferase PSHAa0645 213 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 77358999 Nonpathogen - calmodulin PSHAa0017 1 None None None 77361648 Common - methyl-accepting chemotaxis protein PSHAa2733 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77361448 Nonpathogen - hypothetical protein PSHAa2533 1 None None None 77359023 Nonpathogen - hypothetical protein PSHAa0045 1 None None None 162139924 Common pheS phenylalanyl-tRNA synthetase subunit alpha PSHAa1904 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 77360918 Common - hypothetical protein PSHAa1994 12 None None None 77359384 Common - hypothetical protein PSHAa0418 38 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 77361602 Common mshD Mannose-sensitive agglutinin (MSHA) biogenesis protein MshD (pilus type IV) PSHAa2687 9 COG4795 PulJ, Type II secretory pathway, component PulJ Intracellular trafficking and secretion 77360240 Common - cytochrome PSHAa1297 90 COG3038 CybB, Cytochrome B561 Energy production and conversion 77361016 Nonpathogen - hypothetical protein PSHAa2092 1 None None None 77360106 Common sdaA L-serine deaminase I PSHAa1163 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 77361403 Common ppiC peptidyl-prolyl cis-trans isomerase C (rotamase C) PSHAa2488 138 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 77359497 Common oadB Oxaloacetate decarboxylase, beta subunit PSHAa0540 56 COG1883 OadB, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit Energy production and conversion 77359928 Common prmB N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase PSHAa0982 221 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 77361281 Common ispA geranyltranstransferase (farnesyldiphosphate synthase or FPP synthase) PSHAa2365 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 77359186 Common - hypothetical protein PSHAa0215 3 None None None 77361308 Common tas NADPH-dependent aldose reductase PSHAa2392 200 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 77361140 Common - globin-like PSHAa2217 54 COG2346 COG2346, Truncated hemoglobins General function prediction only 77361663 Common - transport protein (ABC superfamily, ATP-binding) PSHAa2748 62 COG3028 COG3028, Uncharacterized protein conserved in bacteria Function unknown 77360696 Common - urease accessory protein UreD PSHAa1756 82 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 77360213 Common ilvE branched-chain amino acid aminotransferase PSHAa1270 204 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 77361261 Common - hydrolase PSHAa2344 171 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 77360626 Common - hypothetical protein PSHAa1685 32 COG2923 DsrF, Uncharacterized protein involved in the oxidation of intracellular sulfur Inorganic ion transport and metabolism 77360320 Common - hypothetical protein PSHAa1377 50 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 77359854 Common - isovaleryl-CoA dehydrogenase PSHAa0906 156 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77359346 Common pilD leader peptide processing enzyme PSHAa0380 141 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 77361069 Common - hypothetical protein PSHAa2146 55 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 77361764 Nonpathogen - hypothetical protein PSHAa2861 2 None None None 77361037 Common rnt ribonuclease T PSHAa2114 60 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 77361060 Common - protein with ferredoxin subunits PSHAa2137 64 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 77359465 Common - hypothetical protein PSHAa0507 17 None None None 77361514 Common gshB glutathione synthetase PSHAa2599 130 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 77360801 Common - hypothetical protein PSHAa1861 4 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 77359685 Common recO DNA repair protein recO (Recombination protein O) PSHAa0734 62 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 77361495 Nonpathogen - hypothetical protein PSHAa2580 1 None None None 77359612 Common - smp protein PSHAa0660 5 COG3726 AhpA, Uncharacterized membrane protein affecting hemolysin expression General function prediction only 77360080 Common yfgO permease (PerM) PSHAa1137 202 COG0628 PerM, Predicted permease General function prediction only 77359017 Common - hypothetical protein PSHAa0039 7 COG3766 COG3766, Predicted membrane protein Function unknown 77360163 Common nadK NAD kinase PSHAa1220 237 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 77361839 Common mdoG glucan biosynthesis protein G PSHAa2937 50 COG3131 MdoG, Periplasmic glucans biosynthesis protein Inorganic ion transport and metabolism 77361412 Common - nucleotidase PSHAa2497 85 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 77361224 Common - phosphokinase PSHAa2301 150 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 77359209 Common gspJ general secretion pathway protein J PSHAa0238 29 COG4795 PulJ, Type II secretory pathway, component PulJ Intracellular trafficking and secretion 77359800 Common - MltA-interacting MipA ; signal peptide PSHAa0851 21 COG3713 OmpV, Outer membrane protein V Cell envelope biogenesis, outer membrane 77359001 Nonpathogen - calmodulin PSHAa0019 1 None None None 77360311 Common epd glyceraldehyde 3-phosphate dehydrogenase PSHAa1368 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 77359651 Common - regulator in two-component regulatory system ; LuxR PSHAa0699 175 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 77361709 Common rplQ 50S ribosomal protein L17 PSHAa2805 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 77359196 Common rpsG 30S ribosomal protein S7 PSHAa0225 242 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 77361584 Common iscA Fe-S cluster assembly and activation protein (possibly as alternative scaffold for Fe-S cluster assembly) PSHAa2669 165 COG0316 IscA, Uncharacterized conserved protein Function unknown 77361844 Common - succinyl-CoA transferase, beta subunit PSHAa2942 104 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 77361824 Common - aldolase or epimerase PSHAa2922 104 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 77360938 Common accA acetylCoA carboxylase, carboxytransferase subunit alpha PSHAa2014 191 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 77361229 Common - hypothetical protein PSHAa2306 15 None None None 77360198 Common sbcB exonuclease I PSHAa1255 51 COG2925 SbcB, Exonuclease I DNA replication, recombination, and repair 77361358 Nonpathogen - hypothetical protein PSHAa2442 1 None None None 77360781 Nonpathogen - hypothetical protein PSHAa1841 2 None None None 77361623 Common trpS tryptophanyl-tRNA synthetase PSHAa2708 234 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 77360411 Common - transcriptional activator protein, LysR PSHAa1468 179 COG0583 LysR, Transcriptional regulator Transcription 77359409 Common ugd UDP-glucose 6-dehydrogenase PSHAa0444 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 77361382 Nonpathogen - hypothetical protein PSHAa2466 1 None None None 77360172 Common carB carbamoyl phosphate synthase large subunit PSHAa1229 237 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 77361471 Common - magnesium transporter PSHAa2556 170 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 77361429 Common - hypothetical protein PSHAa2514 2 None None None 77359766 Common - hypothetical protein PSHAa0817 14 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 77361830 Common ubiB 2-octaprenylphenol hydroxylase; ubiquinone biosynthesis PSHAa2928 184 COG0661 AarF, Predicted unusual protein kinase General function prediction only 77359369 Common - hypothetical protein PSHAa0403 17 None None None 77359086 Common dbpA ATP-dependent RNA helicase DbpA PSHAa0109 235 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 77359617 Common - hypothetical protein PSHAa0665 34 COG3548 COG3548, Predicted integral membrane protein Function unknown 77361758 Common - hypothetical protein PSHAa2855 17 None None None 77361719 Common rplF 50S ribosomal protein L6 PSHAa2815 234 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 77360161 Common recN DNA repair protein recN PSHAa1218 201 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 77358989 Common - hypothetical protein PSHAa0007 4 None None None 77360392 Common - urea carboxylase (alpha subunit) PSHAa1449 238 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 77360055 Nonpathogen - hypothetical protein PSHAa1112 1 None None None 77360395 Common - Isovaleryl-CoA dehydrogenase PSHAa1452 170 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77361191 Common - Fimh-like protein PSHAa2268 15 None None None 77359419 Common hemH phosphoribosylaminoimidazole-succinocarboxamide synthase PSHAa0454 120 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 77359807 Common - acyltransferase PSHAa0858 74 COG2153 ElaA, Predicted acyltransferase General function prediction only 77359923 Common - oxidoreductase PSHAa0977 161 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 77360438 Common - cytosolic long-chain acyl-CoA thioester hydrolase protein PSHAa1495 120 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 77361808 Nonpathogen - hypothetical protein PSHAa2906 1 COG5589 COG5589, Uncharacterized conserved protein Function unknown 77360181 Common - ribosomal large subunit pseudouridine synthase A (Pseudouridylate synthase, 23S RNA-specific) PSHAa1238 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 77361159 Common nrqF Na(+)-translocating NADH-quinone reductase subunit F PSHAa2236 155 COG2871 NqrF, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF Energy production and conversion 77361712 Common rpsK 30S ribosomal protein S11 PSHAa2808 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 77361212 Common argF Ornithine carbamoyltransferase (OTCase) PSHAa2289 239 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 77359355 Common - regulatory protein AmpE PSHAa0389 39 COG3725 AmpE, Membrane protein required for beta-lactamase induction Defense mechanisms 77359635 Common - cell division protein; septum localization dependent on Ftsl and FtsQ PSHAa0683 64 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 77361794 Common leuD 3-isopropylmalate isomerase, subunit with LeuC PSHAa2891 208 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 77361671 Nonpathogen - hypothetical protein PSHAa2756 1 None None None 77360033 Common dskAC hypothetical protein PSHAa1090 23 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 77360566 Common - ABC-type Na+ efflux pump, permease component PSHAa1625 19 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 77359527 Common - hypothetical protein PSHAa0572 7 None None None 77361692 Common - hypothetical protein PSHAa2777 55 COG3735 COG3735, Uncharacterized protein conserved in bacteria Function unknown 77361335 Common - hypothetical protein PSHAa2419 152 COG1959 COG1959, Predicted transcriptional regulator Transcription 77359903 Common - hypothetical protein PSHAa0957 32 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 77361895 Common glmS L-glutamine:D-fructose-6-phosphate aminotransferase PSHAa2994 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 77360145 Common - conserved protein of unknown function likely to be involved in DNA repair PSHAa1202 190 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 77361360 Common prpE Propionyl CoA synthase PSHAa2444 220 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 77360065 Common bcp thioredoxin-dependent thiol peroxidase PSHAa1122 204 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 77361022 Nonpathogen - hypothetical protein PSHAa2098 1 None None None 77360043 Common rsxE SoxR-reducing system protein RsxE PSHAa1100 76 COG4660 RnfE, Predicted NADH:ubiquinone oxidoreductase, subunit RnfE Energy production and conversion 77361687 Common eptA lipid A phosphoethanolamine transferase, associated with polymyxin resistance PSHAa2772 61 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 77360178 Nonpathogen - hypothetical protein PSHAa1235 1 None None None 77359879 Common ecfD lipoprotein with tetratricopeptide repeats (TPR) domain PSHAa0932 119 COG4105 ComL, DNA uptake lipoprotein General function prediction only 77360070 Nonpathogen - hypothetical protein PSHAa1127 1 None None None 162139927 Common - putative monovalent cation/H+ antiporter subunit C PSHAa1005 92 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 77361652 Common hutI Imidazolonepropionase (imidazolone-5-propionate hydrolase) PSHAa2737 103 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 77360561 Common - acyl-CoA thioester hydrolase protein PSHAa1620 135 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 77361680 Common - beta-carbonic anhydrase PSHAa2765 149 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 77359454 Common - hypothetical protein PSHAa0491 125 COG0432 COG0432, Uncharacterized conserved protein Function unknown 77361628 Common - DamX-related protein PSHAa2713 19 COG3266 DamX, Uncharacterized protein conserved in bacteria Function unknown 77361612 Common mshJ Mannose-sensitive agglutinin (MSHA) biogenesis protein MshJ (pilus type IV) PSHAa2697 10 None None None 77359097 Common - hypothetical protein PSHAa0125 13 COG4508 COG4508, Uncharacterized protein conserved in bacteria Function unknown 77360944 Common - hypothetical protein PSHAa2020 12 COG4890 COG4890, Predicted outer membrane lipoprotein Function unknown 77360657 Common lrp transcriptional regulator of lrp regulon and for high-affinity branched-chain amino acid transport system (AsnC) PSHAa1717 158 COG1522 Lrp, Transcriptional regulators Transcription 77359165 Common argD bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein PSHAa0194 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 77359624 Common - hypothetical protein PSHAa0672 53 COG3123 COG3123, Uncharacterized protein conserved in bacteria Function unknown 77361788 Common - transcriptional regulator PSHAa2885 144 COG0583 LysR, Transcriptional regulator Transcription 77360021 Common - secretion protein PSHAa1078 158 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 77360542 Common gloA Lactoylglutathione lyase (Methylglyoxalase) (Aldoketomutase) (Glyoxalase I) (Glx I) (Ketone-aldehyde mutase) (S-D-lactoylglutathione methylglyoxal lyase) PSHAa1601 120 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 77360356 Nonpathogen - hypothetical protein PSHAa1413 1 None None None 77360248 Nonpathogen - hypothetical protein PSHAa1305 4 COG3895 COG3895, Predicted periplasmic protein General function prediction only 77361683 Common ilvA threonine deaminase PSHAa2768 216 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 77360300 Common - alpha-amylase PSHAa1357 168 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 77360407 Common - hypothetical protein PSHAa1464 6 None None None 77359313 Common dusB tRNA-dihydrouridine synthase B PSHAa0347 213 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 77361490 Common - hypothetical protein PSHAa2575 18 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 77359694 Common mutH DNA mismatch repair protein PSHAa0743 28 COG3066 MutH, DNA mismatch repair protein DNA replication, recombination, and repair 77360083 Common zwf glucose-6-phosphate 1-dehydrogenase PSHAa1140 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 77361742 Common mipA scaffolding protein for murein-synthesizing holoenzyme, outer membrane protein PSHAa2838 34 COG3713 OmpV, Outer membrane protein V Cell envelope biogenesis, outer membrane 77360012 Nonpathogen - hypothetical protein PSHAa1069 1 None None None 77359055 Common - hypothetical protein PSHAa0078 43 COG1944 COG1944, Uncharacterized conserved protein Function unknown 77360586 Common sucC succinyl-CoA synthetase subunit beta PSHAa1645 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 77360400 Common - enoyl-CoA hydratase PSHAa1457 185 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 77360364 Common gyrA DNA gyrase, subunit A, type II topoisomerase PSHAa1421 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 77361003 Common pdxB erythronate-4-phosphate dehydrogenase PSHAa2079 228 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 77361835 Common tatD metal-dependent hydrolase, possibly deoxyribonuclease, TatD PSHAa2933 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 77359136 Common glnL nitrogen availability sensory kinase PSHAa0164 221 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 77359882 Common clpB ATP-dependent protease, Hsp 100, part of multi-chaperone system with DnaK, DnaJ, and GrpE PSHAa0935 217 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 77360869 Nonpathogen - hypothetical protein PSHAa1937 1 None None None 77360652 Common serS seryl-tRNA synthetase PSHAa1712 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 77361904 Common atpD F0F1 ATP synthase subunit beta PSHAa3008 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 77359589 Common - hypothetical protein PSHAa0636 4 None None None 77361237 Common glpE thiosulfate sulfurtransferase PSHAa2314 136 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 77361454 Common - transcriptional regulator PSHAa2539 57 COG5007 COG5007, Predicted transcriptional regulator, BolA superfamily Transcription 77359725 Common flgH flagellar basal body L-ring protein PSHAa0775 101 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 77360908 Common - hypothetical protein PSHAa1984 7 None None None 77359438 Common kamA lysine 2,3 aminomutase PSHAa0473 126 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 77361607 Common mshE Mannose-sensitive agglutinin (MSHA) biogenesis protein MshE (pilus type IV) PSHAa2692 224 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 77360858 Common - NTP pyrophosphatase PSHAa1926 104 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 77360452 Common - hypothetical protein ; DNA-binding protein PSHAa1511 7 None None None 77361728 Common - hypothetical protein PSHAa2824 34 None None None 77361303 Common - chemotaxis sensory protein PSHAa2387 155 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77360711 Common - GalR repressor of contiguous operon, likely to bind a galactoside PSHAa1771 131 COG1609 PurR, Transcriptional regulators Transcription 77359431 Common rffE UDP-N-acetyl glucosamine-2-epimerase PSHAa0466 154 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 77360785 Common - cytochrome c oxidase, subunit CcoP PSHAa1845 78 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 77359919 Common sixA phosphohistidine phosphatase PSHAa0973 31 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 77359910 Common - hypothetical protein PSHAa0964 108 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 77360743 Common tmk thymidylate kinase PSHAa1803 226 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 77359552 Common phoR phosphate regulon sensor protein phoR PSHAa0598 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 77359410 Common ppa putative manganese-dependent inorganic pyrophosphatase PSHAa0445 54 COG1227 PPX1, Inorganic pyrophosphatase/exopolyphosphatase Energy production and conversion 77360641 Common - Na+/H+ antiporter PSHAa1700 46 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 77359956 Common - transcriptional regulator PSHAa1010 104 COG0789 SoxR, Predicted transcriptional regulators Transcription 77361130 Common - carbohydrates permease PSHAa2207 200 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77361443 Common - Ubiquinol-cytochrome c reductase, cytochrome c1 PSHAa2528 49 COG2857 CYT1, Cytochrome c1 Energy production and conversion 77361136 Common adhC alcohol dehydrogenase class III (Glutathione-dependent formaldehyde dehydrogenase )(FDH) (FALDH) PSHAa2213 202 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 77361389 Common gcvH glycine cleavage system protein H PSHAa2474 186 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 77360521 Common - Transcriptional regulator of the TetR/AcrR. PSHAa1580 4 COG1309 AcrR, Transcriptional regulator Transcription 77361600 Nonpathogen mshP Mannose-sensitive agglutinin (MSHA) biogenesis protein MshP (pilus type IV) PSHAa2685 2 None None None 77359865 Common ileS isoleucyl-tRNA synthetase PSHAa0918 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 77359118 Common rplW 50S ribosomal protein L23 PSHAa0146 220 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 77361874 Common - secreted protein PSHAa2972 24 None None None 77360466 Nonpathogen - hypothetical protein PSHAa1525 1 None None None 77361578 Common fbpA Iron(III) ABC transporter periplasmic iron(III)-binding protein PSHAa2663 108 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 77360530 Nonpathogen - hypothetical protein PSHAa1589 2 None None None 77359325 Common - hypothetical protein PSHAa0359 12 None None None 77359015 Common - carbonic anhydrase/acetyltransferase PSHAa0033 188 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 77360427 Common - cytosol aminopeptidase 1 (Leucine aminopeptidase 1) (LAP 1) (Leucyl aminopeptidase 1) PSHAa1484 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 77360204 Common - transcriptional regulator PSHAa1261 190 COG0583 LysR, Transcriptional regulator Transcription 77360754 Common - phosphoglycolate phosphatase, contains a phosphatase-like domain PSHAa1814 138 COG0546 Gph, Predicted phosphatases General function prediction only 77359575 Common - response regulator in two-component regulatory system PSHAa0622 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77360731 Common - hypothetical protein PSHAa1791 8 COG3594 NolL, Fucose 4-O-acetylase and related acetyltransferases Carbohydrate transport and metabolism 77361027 Nonpathogen - hypothetical protein PSHAa2103 1 None None None 77360765 Common - transmembrane sensor PSHAa1825 47 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 77359004 Common fmt 10-formyltetrahydrofolate:L-methionyl-tRNA(fMet) N-formyltransferase PSHAa0022 216 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 77359285 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase PSHAa0318 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 77359288 Common secD preprotein translocase auxillary membrane component PSHAa0321 214 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 77361186 Common lrp leucine-responsive regulatory protein PSHAa2263 135 COG1522 Lrp, Transcriptional regulators Transcription 77361222 Common mpl UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase (Murein peptide ligase) PSHAa2299 208 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 77359582 Common - outer membrane protein PSHAa0629 123 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 77361366 Common - hypothetical protein PSHAa2450 13 None None None 77361913 Common parA partitioning protein A PSHAa3017 227 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 77359748 Common fliM flagellar motor switch protein FliM PSHAa0799 113 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 77360486 Nonpathogen - hypothetical protein PSHAa1545 1 None None None 77360074 Common - hypothetical protein PSHAa1131 23 COG3308 COG3308, Predicted membrane protein Function unknown 77359514 Common - Secretion protein PSHAa0559 147 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 77359778 Common ccmH cytochrome c-type biogenesis protein CcmH PSHAa0829 86 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 77361586 Common iscS cysteine desulfurase (tRNA sulfurtransferase; RNA 4-thiouridine sulfurtransferase), PLP-dependent PSHAa2671 240 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 77359066 Common - hypothetical protein PSHAa0089 73 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 77360948 Common lpxA UDP-N-acetylglucosamine acyltransferase PSHAa2024 159 COG1043 LpxA, Acyl- acyl carrier protein 77361884 Common - hypothetical protein PSHAa2982 30 None None None 77360536 Nonpathogen - hypothetical protein PSHAa1595 2 None None None 77361817 Common - cold-active aminopeptidase PSHAa2915 128 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 77360398 Common - Methylmalonate-semialdehyde dehydrogenase PSHAa1455 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77359901 Common - hypothetical protein PSHAa0955 3 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 77360813 Common ruvB Holliday junction DNA helicase B PSHAa1875 232 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 77360316 Nonpathogen - hypothetical protein PSHAa1373 1 None None None 77360227 Nonpathogen - hypothetical protein PSHAa1284 2 None None None 77361373 Common - TonB-dependent receptor PSHAa2457 32 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 77359070 Common lysA diaminopimelate decarboxylase PSHAa0093 218 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 77361230 Common - hypothetical protein PSHAa2307 20 None None None 77359618 Common serA D-3-phosphoglycerate dehydrogenase PSHAa0666 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 77359427 Nonpathogen - hypothetical protein PSHAa0462 1 None None None 77361257 Common gsk inosine-guanosine kinase PSHAa2334 69 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 77360962 Common glnD uridylyltransferase PSHAa2038 123 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 77359546 Common - complement resistance protein precursor PSHAa0591 18 None None None 77360600 Common - hypothetical protein PSHAa1659 101 COG2835 COG2835, Uncharacterized conserved protein Function unknown 77361266 Common - hypothetical protein PSHAa2350 5 None None None 77360046 Common rsxC electron transport complex protein RnfC PSHAa1103 83 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 77361524 Common yggW oxygen-independent coproporphyrinogen III oxidase PSHAa2609 206 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 77361558 Common radC associated with replication fork DNA repair protein PSHAa2643 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 77359499 Nonpathogen - hypothetical protein PSHAa0542 1 None None None 77360271 Nonpathogen - hypothetical protein PSHAa1328 1 None None None 77361120 Common - hypothetical protein PSHAa2197 6 None None None 77360688 Common alyll chondroitin AC/alginate lyase PSHAa1748 8 None None None 77360622 Common - hypothetical protein PSHAa1681 81 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 77361020 Nonpathogen - hypothetical protein PSHAa2096 1 None None None 77361129 Common - TonB-dependent receptor PSHAa2206 50 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 77361190 Common - ATPase and membrane protein PSHAa2267 72 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 77361181 Common glnK Nitrogen regulatory protein P-II PSHAa2258 187 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 77359181 Common snaA sodium/sulfate symporter PSHAa0210 125 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 77360238 Common yciO RNA binding protein PSHAa1295 218 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 77360565 Common - sensor protein PSHAa1624 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77359530 Common - transcriptional regulator PSHAa0575 133 COG0789 SoxR, Predicted transcriptional regulators Transcription 77361553 Common - methyl-accepting chemotaxis protein PSHAa2638 147 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77359946 Common rpsO 30S ribosomal subunit protein S15 PSHAa1000 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 77361806 Common - nucleic-acid-binding protein PSHAa2904 10 COG3529 COG3529, Predicted nucleic-acid-binding protein containing a Zn-ribbon domain General function prediction only 77359440 Common - fold recognizing lysyl-tRNA PSHAa0475 221 COG2269 COG2269, Truncated, possibly inactive, lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 77360323 Common - hypothetical protein PSHAa1380 165 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 77361920 Nonpathogen - hypothetical protein PSHAa3024 1 None None None 77361486 Common - hypothetical protein PSHAa2571 49 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 77361156 Nonpathogen - hypothetical protein PSHAa2233 1 None None None 77361341 Common valS valine tRNA synthetase PSHAa2425 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 77360132 Common ExbB2 TonB system transport protein ExbB2 PSHAa1189 115 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 77360893 Common - hypothetical protein PSHAa1968 19 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 77361714 Common secY preprotein translocase, membrane component, transport across inner membrane (General Secretory Pathway) PSHAa2810 245 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 77360700 Common ureE urease accessory chaperone protein PSHAa1760 60 COG2371 UreE, Urease accessory protein UreE Posttranslational modification, protein turnover, chaperones 77360339 Common thrS threonyl-tRNA synthetase PSHAa1396 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 77361653 Common hutC histidine utilization repressor PSHAa2738 123 COG2188 PhnF, Transcriptional regulators Transcription 77361751 Common - Alpha-glucosidase PSHAa2848 18 None None None 77360509 Common - enzymatic protein PSHAa1568 101 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 77360126 Common pyrC dihydroorotase PSHAa1183 88 COG0418 PyrC, Dihydroorotase Nucleotide transport and metabolism 77359731 Common - flagellin (fliC-like) PSHAa0782 119 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 77361476 Common ung uracil-DNA glycosylase PSHAa2561 128 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 77360990 Common ppiB peptidyl-prolyl cis-trans isomerase B (rotamase B) PSHAa2066 200 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 77359709 Common - peroxiredoxin/glutaredoxin protein PSHAa0759 121 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 77359892 Common trmD tRNA (guanine-7-)-methyltransferase PSHAa0946 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 77359307 Common - hypothetical protein PSHAa0340 3 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 77359962 Common - secreted calmodulin-like protein PSHAa1016 2 None None None 77359933 Common - hypothetical protein PSHAa0987 26 COG3199 COG3199, Uncharacterized conserved protein Function unknown 77359077 Common hemY heme biosynthesis protein PSHAa0100 13 COG3071 HemY, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 77359845 Common - acyl-CoA synthetase PSHAa0896 207 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 77361317 Common - hypothetical protein PSHAa2401 13 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 77361250 Common - hypothetical protein PSHAa2327 26 COG3784 COG3784, Uncharacterized protein conserved in bacteria Function unknown 77361777 Nonpathogen - hypothetical protein PSHAa2874 3 None None None 77361438 Common - hypothetical protein PSHAa2523 123 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 77361733 Nonpathogen - hypothetical protein PSHAa2829 1 None None None 77360925 Common - Predicted transporter component PSHAa2001 61 None None None 77359145 Common - acyltransferase PSHAa0174 44 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 77361326 Common - endoribonuclease with L-PSP Domain PSHAa2410 176 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 77359688 Common barA hybrid sensory histidine kinase BarA PSHAa0737 226 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77359961 Common - secreted calmodulin-like protein PSHAa1015 3 None None None 77361721 Common rpsN 30S ribosomal protein S14 PSHAa2817 210 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 77359449 Common thiF adenylyltransferase PSHAa0485 216 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 77359970 Common mrdB rod shape-determining membrane protein; cell elongation PSHAa1024 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 77359675 Nonpathogen - hypothetical protein; membrane protein PSHAa0724 1 None None None 77359171 Common sdaC serine transport protein PSHAa0200 32 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 77359537 Common - transposase (IS605) PSHAa0582 70 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 77360637 Common - leucine aminopeptidase-related protein PSHAa1696 27 COG2234 Iap, Predicted aminopeptidases General function prediction only 77360290 Common - hypothetical protein PSHAa1347 22 None None None 77360232 Common trpB tryptophan synthase subunit beta PSHAa1289 225 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 77360999 Common truA tRNA pseudouridine synthase A PSHAa2075 236 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 77359564 Common - hypothetical protein PSHAa0610 5 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 77359108 Common atoE short-chain fatty acid transport protein PSHAa0136 43 COG2031 AtoE, Short chain fatty acids transporter Lipid metabolism 77359402 Common - GGDEF domain PSHAa0436 167 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 77359660 Common - hypothetical protein PSHAa0708 4 None None None 77361118 Common baeR Transcriptional regulatory protein in two-component regulatory system with baeS PSHAa2195 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77360860 Common - hypothetical protein PSHAa1928 8 None None None 77361694 Common - fatty acid cis/trans isomerase PSHAa2779 15 None None None 77359300 Common - transporter PSHAa0333 103 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 77360500 Common - hypothetical protein PSHAa1559 14 None None None 77360721 Common - polysaccharide export-related protein PSHAa1781 109 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 77360251 Common - quinone oxidoreductase, NADPH-dependent PSHAa1308 184 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 77361352 Common - hypothetical protein PSHAa2436 23 COG3595 COG3595, Uncharacterized conserved protein Function unknown 77359486 Common ribA GTP cyclohydrolase II PSHAa0529 172 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 77359715 Common flgA flagellar biosynthesis; assembly of basal-body periplasmic P-ring PSHAa0765 33 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 77359420 Common - hypothetical protein PSHAa0455 17 COG3794 PetE, Plastocyanin Energy production and conversion 77359810 Common - transcriptional regulatory protein RstA PSHAa0861 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77361703 Common - ribonuclease (endoribonuclease L-PSP) PSHAa2794 188 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 77359251 Common - nucleoprotein/polynucleotide-associated enzyme PSHAa0284 31 COG3122 COG3122, Uncharacterized protein conserved in bacteria Function unknown 77361792 Common - secreted protein PSHAa2889 9 None None None 77359813 Nonpathogen - hypothetical protein ; signal peptide PSHAa0864 1 None None None 77360718 Common - hypothetical protein PSHAa1778 3 None None None 77360980 Nonpathogen - hypothetical protein PSHAa2056 1 None None None 77359551 Common phoB transcriptional regulator PSHAa0597 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77360375 Common srmB ATP-dependent RNA helicase, DEAD box PSHAa1432 238 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 77359342 Common - hypothetical protein PSHAa0376 14 COG3678 CpxP, P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein Intracellular trafficking and secretion / Cell motility and secretio / Signal transduction mechanisms / Inorganic ion transport and metabolism 77361646 Common hslU ATP-dependent protease ATP-binding subunit PSHAa2731 209 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 77359025 Nonpathogen - hypothetical protein PSHAa0047 1 None None None 77360128 Nonpathogen - hypothetical protein PSHAa1185 1 None None None 77360568 Common - hypothetical protein PSHAa1627 14 None None None 77359550 Common fbaA fructose-1,6-bisphosphate aldolase PSHAa0596 161 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 77361014 Nonpathogen - hypothetical protein PSHAa2090 1 None None None 77360911 Common - TonB-dependent receptor protein PSHAa1987 113 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 77361333 Common nor Nitric oxide reductase PSHAa2417 73 COG3256 NorB, Nitric oxide reductase large subunit Inorganic ion transport and metabolism 77360639 Common - ABC transporter ATP-binding/permease protein PSHAa1698 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 77360090 Common yccW methyltransferase with S-adenosyl-L-methionine-dependent methyltransferase activity and a PUA domain. PSHAa1147 141 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 77359257 Common - hypothetical protein PSHAa0290 28 COG3618 COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 77359292 Common osmY hypothetical protein PSHAa0325 59 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 77359037 Common - hypothetical protein PSHAa0060 6 None None None 77361591 Common - hydrolase, carbon-nitrogen PSHAa2676 197 COG0388 COG0388, Predicted amidohydrolase General function prediction only 77361067 Common - transporter PSHAa2144 170 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77360544 Common - hypothetical protein PSHAa1603 22 COG0431 COG0431, Predicted flavoprotein General function prediction only 77361149 Common - histone deacetylase protein PSHAa2226 151 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 77360669 Common - enzyme PSHAa1729 60 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 77361283 Common - hypothetical protein PSHAa2367 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 77360211 Common - Oxidoreductase PSHAa1268 97 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 77360923 Common - SalD PSHAa1999 62 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 77359237 Common miaA delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase PSHAa0270 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 77359850 Common - acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit PSHAa0902 33 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 77361762 Common - hypothetical protein PSHAa2859 16 None None None 77360188 Common - hypothetical protein PSHAa1245 9 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 77360292 Nonpathogen - hypothetical protein PSHAa1349 1 None None None 77360436 Common - hypothetical protein PSHAa1493 15 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 77360901 Common - hypothetical protein PSHAa1977 4 None None None 77359348 Common - hypothetical protein ; membrane protein, fimbrial assembly protein PSHAa0382 2 None None None 77359857 Common - short chain dehydrogenase PSHAa0909 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77359188 Common nusG transcription antitermination factor PSHAa0217 215 COG0250 NusG, Transcription antiterminator Transcription 77360134 Common TonB2 TonB2 protein; iron acquisition via a siderophore-mediated active transport. PSHAa1191 22 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 77360624 Common - transport protein (TEGT) (partial match) PSHAa1683 135 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 77359539 Common - hypothetical protein PSHAa0584 25 COG5373 COG5373, Predicted membrane protein Function unknown 162139929 Common fliR flagellar biosynthesis protein FliR PSHAa0804 128 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 77361122 Common - conserved protein of unknown function with domain typically associated with flavoprotein oxygenase PSHAa2199 81 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 77361542 Common rluA pseudouridylate synthase for 23S rRNA (position 746) and tRNAphe(position 32), dual specificity PSHAa2627 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 77360826 Common - cyanophycinase PSHAa1888 4 COG4242 CphB, Cyanophycinase and related exopeptidases Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism 77361669 Common - hypothetical protein PSHAa2754 45 COG3816 COG3816, Uncharacterized protein conserved in bacteria Function unknown 77359124 Common rpmC 50S ribosomal subunit protein L29 PSHAa0152 155 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 77359150 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase PSHAa0179 151 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 77360705 Common prpD 2-methylcitrate dehydratase PSHAa1765 58 COG2079 PrpD, Uncharacterized protein involved in propionate catabolism General function prediction only 77361209 Nonpathogen - hypothetical protein PSHAa2286 1 None None None 77360616 Common - hypothetical protein PSHAa1675 4 None None None 77360064 Common - hypothetical protein PSHAa1121 22 None None None 77360159 Common - conserved protein of unknown function with thioredoxin-like domain PSHAa1216 126 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 77359995 Common pth peptidyl-tRNA hydrolase PSHAa1052 215 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 77359528 Common - transcriptional regulator PSHAa0573 91 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77359647 Common - outer membrane receptor for ferric iron uptake ; TonB-dependent receptor PSHAa0695 96 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 77360691 Common - hypothetical protein PSHAa1751 28 COG3560 FMR2, Predicted oxidoreductase related to nitroreductase General function prediction only 77359669 Common - dsDNA-mimic protein PSHAa0718 18 COG3099 COG3099, Uncharacterized protein conserved in bacteria Function unknown 77360009 Common - hypothetical protein PSHAa1066 71 COG2363 COG2363, Uncharacterized small membrane protein Function unknown 77360217 Common dgt deoxyguanosinetriphosphate triphosphohydrolase-like protein PSHAa1274 159 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 77361249 Common - hypothetical protein PSHAa2326 30 COG3310 COG3310, Uncharacterized protein conserved in bacteria Function unknown 77359159 Common - hypothetical protein PSHAa0188 38 COG0824 FcbC, Predicted thioesterase General function prediction only 77359429 Common - hypothetical protein PSHAa0464 19 None None None 77361643 Common priA Primosome factor Y, also called protein n'; ATP-dependent DNA helicase activity required for recA-dependent stable DNA replication mode; also involved in double-strand break repair PSHAa2728 212 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 77360075 Common - Trp repressor binding protein WrbA PSHAa1132 96 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 77360811 Common tolR tol protein, role in outer membrane integrity, uptake of group A colicins (TonB-independent), and phage DNA PSHAa1873 128 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 77360698 Common ureB urease subunit beta PSHAa1758 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 77361193 Common - hypothetical protein PSHAa2270 2 None None None 77360372 Common pyrF orotidine-5'-phosphate decarboxylase PSHAa1429 159 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 77361873 Common - hypothetical protein PSHAa2971 26 COG3656 COG3656, Predicted periplasmic protein Function unknown 77359785 Nonpathogen - hypothetical protein PSHAa0836 1 None None None 77360682 Common - fructose-1,6-bisphosphatase PSHAa1742 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 77360527 Common atoB beta-ketothiolase PSHAa1586 179 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 77359832 Common fabG short chain dehydrogenase PSHAa0883 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77359746 Common fliK flagellar hook-length control protein PSHAa0797 54 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 77361505 Common - hypothetical protein PSHAa2590 24 COG3151 COG3151, Uncharacterized protein conserved in bacteria Function unknown 77359299 Nonpathogen - hypothetical protein PSHAa0332 3 None None None 77361478 Common btuR cob(I)yrinic acid a,c-diamide adenosyltransferase PSHAa2563 141 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 77359871 Common - type IV pilus biogenesis protein; membrane protein PSHAa0924 28 COG4967 PilV, Tfp pilus assembly protein PilV Cell motility and secretion / Intracellular trafficking and secretion 77359600 Common xseA exodeoxyribonuclease VII large subunit PSHAa0647 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 77361530 Common - Sensory box protein PSHAa2615 187 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 77359117 Common rplD 50S ribosomal protein L4 PSHAa0145 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 77360522 Nonpathogen - hypothetical protein PSHAa1581 1 None None None 77360887 Common - hypothetical protein PSHAa1962 12 None None None 77359623 Common tktA transketolase 1 (TK 1) PSHAa0671 221 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 77361857 Common ptrB oligopeptidase, type B PSHAa2955 102 COG1770 PtrB, Protease II Amino acid transport and metabolism 77360389 Common atoA succinyl-CoA transferase, beta subunit PSHAa1446 101 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 77359501 Common tyrZ Tyrosyl-tRNA synthetase II PSHAa0545 242 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 77359370 Common - transposase PSHAa0404 15 None None None 77360263 Common - hypothetical protein PSHAa1320 13 None None None 77361467 Common - hypothetical protein PSHAa2552 126 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 77359626 Common - hypothetical protein PSHAa0674 18 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 77360057 Common - hypothetical protein PSHAa1114 4 None None None 77361786 Common norR anaerobic nitric oxide reductase transcription regulator PSHAa2883 170 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 77359658 Common - hypothetical protein PSHAa0706 11 None None None 77360336 Common - GTP-binding protein PSHAa1393 214 COG2262 HflX, GTPases General function prediction only 77360797 Common recD exonuclease V, alpha chain with recC and recD: 5' and 3' nuclease, ATPase, recombinase, helicase PSHAa1857 123 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 77360532 Common uhpA response regulator (activator) in two-component regulatory system wtih UhpB, regulates uhpT expression (LuxR/UhpA) PSHAa1591 171 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 77361241 Common - ADP-heptose:LPS heptosyltransferase PSHAa2318 111 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 77359925 Common - transcriptional regulator PSHAa0979 189 COG0583 LysR, Transcriptional regulator Transcription 77360727 Common - glycosyl transferase PSHAa1787 3 None None None 77361202 Common - 2-dehydropantoate reductase PSHAa2279 81 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 77359266 Common - hypothetical protein PSHAa0299 34 COG3126 COG3126, Uncharacterized protein conserved in bacteria Function unknown 77359839 Common - acyl-CoA dehydrogenase protein PSHAa0890 133 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77361339 Common pepA leucyl aminopeptidase PSHAa2423 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 77360958 Common pyrH uridylate kinase; belongs to the aspartate/carbamate kinase; hexamer PSHAa2034 235 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 77360744 Common - hypothetical protein PSHAa1804 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 77361347 Common - transporter protein PSHAa2431 54 COG3201 PnuC, Nicotinamide mononucleotide transporter Coenzyme metabolism 77359809 Common - hypothetical protein ; sensory histidine kinase in two-component regulatory system PSHAa0860 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77361621 Common - transporter (MFS) PSHAa2706 201 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77360031 Common - TPR motives PSHAa1088 29 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 77361188 Common - metal-dependent phosphohydrolase domain PSHAa2265 122 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 77361213 Common argB acetylglutamate kinase PSHAa2290 197 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 77359632 Common - hypothetical protein PSHAa0680 37 COG4728 COG4728, Uncharacterized protein conserved in bacteria Function unknown 77360023 Common - RNA methyltransferase, TrmH PSHAa1080 197 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 77361610 Common mshL Mannose-sensitive agglutinin (MSHA) biogenesis protein MshL (pilus type IV) PSHAa2695 142 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 77359260 Common mltD murein transglycosylase D PSHAa0293 119 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 77361362 Common - bacterial regulatory protein PSHAa2446 94 COG0583 LysR, Transcriptional regulator Transcription 77359485 Common - TonB domain protein PSHAa0528 23 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 77360439 Common - hypothetical protein PSHAa1496 30 COG2056 COG2056, Predicted permease General function prediction only 77360837 Common - Zinc carboxypeptidase domain protein PSHAa1899 30 COG2866 COG2866, Predicted carboxypeptidase Amino acid transport and metabolism 77360294 Common - alpha-glucosidase PSHAa1351 162 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 77359375 Common - hypothetical protein PSHAa0409 50 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 77359653 Common purU formyltetrahydrofolate hydrolase PSHAa0701 219 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 77359463 Common - hypothetical protein PSHAa0505 19 None None None 77361685 Common ilvM acetolactate synthase 2 regulatory subunit PSHAa2770 21 COG3978 COG3978, Acetolactate synthase (isozyme II), small (regulatory) subunit Function unknown 77359935 Common - transporter PSHAa0989 41 COG2978 AbgT, Putative p-aminobenzoyl-glutamate transporter Coenzyme metabolism 77359577 Nonpathogen - hypothetical protein PSHAa0624 1 None None None 77359088 Common - hypothetical protein PSHAa0111 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77361375 Common - hypothetical protein PSHAa2459 11 None None None 77360234 Common trpD Anthranilate phosphoribosyltransferase PSHAa1291 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 77359521 Nonpathogen - hypothetical protein PSHAa0566 3 None None None 77360491 Nonpathogen - hypothetical protein PSHAa1550 1 None None None 77360369 Common ihfB integration host factor (iHF), beta subunit, site-specific recombination PSHAa1426 205 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 77360081 Common - enzyme of the cysteine desulfurase, metallo-beta-lactamase superfamily PSHAa1138 237 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 77359274 Nonpathogen - hypothetical protein PSHAa0307 1 None None None 77359764 Common motB chemotaxis protein PSHAa0815 139 COG1360 MotB, Flagellar motor protein Cell motility and secretion 77359683 Common rnc RNase III, ds RNA PSHAa0732 216 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 77361399 Common - Bacterial chemotaxis sensory transducer PSHAa2484 94 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77360041 Nonpathogen - hypothetical protein PSHAa1098 1 None None None 77360165 Common grpE nucleotide exchange factor PSHAa1222 231 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 77359758 Common fliA flagellar biosynthesis sigma factor PSHAa0809 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 77359775 Common ccmE cytochrome c-type biogenesis protein CcmE PSHAa0826 95 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 77360985 Common clpX ATP-dependent protease ATP-binding subunit PSHAa2061 231 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 77360405 Nonpathogen - hypothetical protein PSHAa1462 1 None None None 77360803 Common - Oxidoreductase, FMN-binding PSHAa1863 177 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 77358984 Common dnaN DNA polymerase III subunit beta PSHAa0002 214 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 77360848 Common uvrY response regulator PSHAa1916 214 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 77359802 Common rstA response regulator (activator) in two-component regulatory PSHAa0853 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77361093 Common - peptidase M23/M37 protein PSHAa2170 189 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 77360459 Common - hypothetical protein PSHAa1518 2 None None None 77360769 Common - cytochrome c precursor PSHAa1829 70 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 77361626 Common - hypothetical protein PSHAa2711 3 None None None 77360424 Common - hypothetical protein PSHAa1481 27 None None None 77359323 Common rpoH RNA polymerase factor sigma-32 PSHAa0357 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 77361769 Common - Cytochrome oxidase assembly protein PSHAa2866 57 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 77361376 Common - bacterial regulatory protein PSHAa2460 180 COG0583 LysR, Transcriptional regulator Transcription 77360008 Common - hypothetical protein PSHAa1065 37 COG3571 COG3571, Predicted hydrolase of the alpha/beta-hydrolase fold General function prediction only 77359848 Common tesB dioxygenase PSHAa0900 21 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 77359336 Common gpsA glycerol-3-phosphate dehydrogenase (NAD+) PSHAa0370 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 77361380 Nonpathogen - hypothetical protein PSHAa2464 1 None None None 77360790 Common fnr fumarate/nitrate reduction transcriptional regulator PSHAa1850 147 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 77361401 Common - acetyltransferase PSHAa2486 99 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 77361048 Nonpathogen - hypothetical protein PSHAa2125 2 None None None 77360196 Common - Glutathione peroxidase PSHAa1253 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 77360354 Common - nitroreductase PSHAa1411 83 COG0778 NfnB, Nitroreductase Energy production and conversion 77361799 Common - long chain acyl-CoA desaturase PSHAa2897 47 COG1398 OLE1, Fatty-acid desaturase Lipid metabolism 77360176 Common ribB 3,4 dihydroxy-2-butanone-4-phosphate synthase PSHAa1233 229 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 77361315 Common - nudix hydrolase protein PSHAa2399 14 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 77361864 Common - hypothetical protein PSHAa2962 8 COG2912 COG2912, Uncharacterized conserved protein Function unknown 77361661 Common - hypothetical protein PSHAa2746 11 COG4701 COG4701, Uncharacterized protein conserved in bacteria Function unknown 77359472 Common xerD site-specific tyrosine recombinase XerD PSHAa0514 233 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 77360474 Nonpathogen - hypothetical protein PSHAa1533 1 None None None 77360174 Common - hypothetical protein PSHAa1231 151 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism