Streptococcus agalactiae A909, complete genome NC_007432 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 76788284 Common - HIT family protein SAK_1802 28 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 76787555 Common secA preprotein translocase subunit SecA SAK_1482 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 76786855 Common - acyl carrier protein SAK_0056 170 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 76787781 Pathogen - hypothetical protein SAK_1632 1 None None None 76786790 Common - ISSag5, transposase orfA SAK_0773 26 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 76787161 Common - hypothetical protein SAK_1058 13 COG4086 COG4086, Predicted secreted protein Function unknown 76787958 Common - hypothetical protein SAK_1352 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 76788251 Common - hydrolase, NUDIX family SAK_1479 64 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 76787024 Common lysS lysyl-tRNA synthetase SAK_0876 248 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 76787947 Common - oxidoreductase, NAD-binding SAK_0264 65 COG4097 COG4097, Predicted ferric reductase Inorganic ion transport and metabolism 76787930 Common - competence protein, putative SAK_0229 2 None None None 76787138 Common potB spermidine/putrescine ABC transporter, permease protein PotB SAK_1195 202 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 76786830 Common - cyclodextrin ABC transporter, permease protein SAK_1476 143 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 76788141 Common - hypothetical protein SAK_1648 17 COG4720 COG4720, Predicted membrane protein Function unknown 76786745 Common - ATP-dependent RNA helicase, DEAD/DEAH box family SAK_0949 231 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 76788302 Common - hypothetical protein SAK_1668 26 COG1323 COG1323, Predicted nucleotidyltransferase General function prediction only 76788051 Common glpF glycerol uptake facilitator protein SAK_0347 136 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 76788575 Common - PTS system, IID component, mannose/fructose/sorbose family SAK_0433 41 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 76786818 Common rpsR 30S ribosomal protein S18 SAK_1720 215 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 76788437 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B SAK_1679 213 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 76787312 Common - hypothetical protein SAK_0588 3 None None None 76787660 Common - hypothetical protein SAK_1128 8 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 76787534 Common ligA NAD-dependent DNA ligase LigA SAK_0973 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 76787479 Common - hypothetical protein SAK_1174 3 None None None 76788544 Common - hypothetical protein SAK_0880 88 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 76788563 Common ahpF NADH dehydrogenase SAK_1854 248 COG3634 AhpF, Alkyl hydroperoxide reductase, large subunit Posttranslational modification, protein turnover, chaperones 76787708 Common - hypothetical protein SAK_0558 11 COG4470 COG4470, Uncharacterized protein conserved in bacteria Function unknown 76788066 Common recN DNA repair protein RecN SAK_0602 224 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 76787839 Common - hypothetical protein SAK_2077 5 COG3600 GepA, Uncharacterized phage-associated protein Function unknown 76787754 Common - acetyltransferase, GNAT family SAK_0993 37 COG0456 RimI, Acetyltransferases General function prediction only 76788324 Common - adaptor protein SAK_0197 12 COG4862 MecA, Negative regulator of genetic competence, sporulation and motility Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Cell motility and secretion 76787339 Common - peptide/opine/nickel uptake (PepT) family ABC transporter, ATP-binding protein SAK_0256 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 76787793 Common - peptide/opine/nickel uptake (PepT) family ABC transporter, permease protein SAK_0253 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 76788315 Common - bifunctional glutamate--cysteine ligase/glutathione synthetase SAK_1841 96 COG2918 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 76787329 Common holB DNA polymerase III subunit delta' SAK_1590 205 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 76787152 Common - hypothetical protein SAK_0337 2 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 76787311 Common - phosphate ABC transporter, ATP-binding protein PstB, putative SAK_1083 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 76787776 Common - hypothetical protein SAK_2130 11 COG4485 COG4485, Predicted membrane protein Function unknown 76787830 Common - amidase family protein SAK_1504 217 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 76787901 Common - tellurite resistance protein, putative SAK_1843 21 COG3853 TelA, Uncharacterized protein involved in tellurite resistance Inorganic ion transport and metabolism 76787373 Common - prophage LambdaSa03, tail component, putative SAK_0646 3 COG4722 COG4722, Phage-related protein Function unknown 76787636 Common copY transcriptional repressor CopY SAK_0458 30 COG3682 COG3682, Predicted transcriptional regulator Transcription 76786799 Common - competence protein, putative SAK_0228 3 COG4537 ComGC, Competence protein ComGC Intracellular trafficking and secretion 76787694 Common murG N-acetylglucosaminyl transferase SAK_0578 207 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 76786840 Common - acyltransferase family protein SAK_0905 66 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 76786847 Pathogen - hypothetical protein SAK_1131 1 None None None 76787805 Common cadX cadmium resistance accessory protein CadX SAK_2052 81 COG0640 ArsR, Predicted transcriptional regulators Transcription 76787198 Common - CRISPR-associated SAG0897 family protein SAK_1020 2 None None None 76786887 Common asp1 accessory secretory protein Asp1 SAK_1485 6 None None None 76787295 Common - acetyl xylan esterase, putative SAK_0074 20 COG3458 COG3458, Acetyl esterase (deacetylase) Secondary metabolites biosynthesis, transport, and catabolism 76786727 Common - hypothetical protein SAK_1159 6 COG3081 COG3081, Nucleoid-associated protein General function prediction only 76787159 Common ctsR transcriptional regulator CtsR SAK_1849 22 COG4463 CtsR, Transcriptional repressor of class III stress genes Transcription 76787405 Common - transcriptional activator, Rgg/GadR/MutR family SAK_1520 7 COG1396 HipB, Predicted transcriptional regulators Transcription 76787803 Common - RNA pseudouridine synthase family protein SAK_0926 205 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 76788682 Pathogen - hypothetical protein SAK_0285 1 None None None 76786974 Common - hypothetical protein SAK_0375 3 None None None 76786812 Common - hypothetical protein SAK_1836 5 None None None 76788679 Common - K+ transporter (Trk) family protein TrkH, putative SAK_1606 144 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 76787513 Common - C protein alpha-antigen SAK_0517 7 None None None 76787372 Common - transposase OrfB, IS3 family, truncation SAK_0703 142 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 76788668 Common - hypothetical protein SAK_0233 10 COG0827 COG0827, Adenine-specific DNA methylase DNA replication, recombination, and repair 76787431 Pathogen - hypothetical protein SAK_1332 1 COG5155 ESP1, Separase, a protease involved in sister chromatid separation Cell division and chromosome partitioning / Posttranslational modification, protein turnover, chaperones 76787300 Common - hypothetical protein SAK_1339 2 None None None 76788152 Common alr alanine racemase SAK_1696 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 76788670 Common rplQ 50S ribosomal protein L17 SAK_0117 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 76787894 Pathogen - hypothetical protein SAK_0755 1 None None None 76788461 Common - ABC transporter, ATP-binding protein SAK_1393 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 76787625 Common - GtrA family protein SAK_0971 8 COG2246 COG2246, Predicted membrane protein Function unknown 76787280 Common - beta-lactam resistance factor SAK_1380 10 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 76788347 Common - DNA-binding protein SAK_0081 1 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 76788019 Common - sensor histidine kinase SAK_0175 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76787047 Common - Cof-like hydrolase SAK_0661 139 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 76787612 Common neuA N-acylneuraminate cytidylyltransferase SAK_1247 74 COG1083 NeuA, CMP-N-acetylneuraminic acid synthetase Cell envelope biogenesis, outer membrane 76788165 Common - Cof-like hydrolase family protein SAK_0851 115 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 76787876 Common eda 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase SAK_0826 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 76786783 Common - putative L-ascorbate 6-phosphate lactonase SAK_1820 25 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 76788441 Common - maltose O-acetyltransferase SAK_1106 174 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 76788489 Common - DNA-binding response regulator SAK_0249 173 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 76787581 Common - hypothetical protein SAK_0556 38 COG3480 SdrC, Predicted secreted protein containing a PDZ domain Signal transduction mechanisms 76788459 Common - R3H domain protein SAK_0483 62 COG1847 Jag, Predicted RNA-binding protein General function prediction only 76788096 Common - ammonium transporter (Amt) family protein SAK_1467 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 76787414 Common - permease, putative SAK_0855 91 COG0701 COG0701, Predicted permeases General function prediction only 76788684 Common - acetyltransferase, GNAT family SAK_1937 11 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 76787206 Common - GDXG lipolytic enzyme family protein SAK_0457 41 COG0657 Aes, Esterase/lipase Lipid metabolism 76787019 Common - glycosyl transferase, group 1 family protein SAK_1445 194 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 76787106 Common - transglycosylase associated protein SAK_1227 8 COG2261 COG2261, Predicted membrane protein Function unknown 76787460 Pathogen - hypothetical protein SAK_0296 1 None None None 76788699 Common - hypothetical protein SAK_0140 8 None None None 76787355 Common pyk pyruvate kinase SAK_1037 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 76788004 Pathogen - prophage LambdaSa03, HNH endonuclease family protein SAK_0630 1 COG1403 McrA, Restriction endonuclease Defense mechanisms 76788519 Common - hypothetical protein SAK_0683 54 COG1481 COG1481, Uncharacterized protein conserved in bacteria Function unknown 76788018 Common - IS861, transposase orfB SAK_1550 143 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 76788224 Common - CAAX amino terminal protease family protein SAK_1097 33 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 76788039 Common rnpA ribonuclease P SAK_0481 84 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 76788372 Common - hypothetical protein SAK_2093 11 None None None 76786921 Common - glycosyl transferase, group 1 family protein SAK_0836 217 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 76787182 Common - hypothetical protein SAK_1521 13 COG5279 CYK3, Uncharacterized protein involved in cytokinesis, contains TGc (transglutaminase/protease-like) domain Cell division and chromosome partitioning 76788291 Common sdhA L-serine dehydratase, iron-sulfur-dependent, alpha subunit SAK_2104 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 76786777 Common - glutaredoxin-like protein NrdH SAK_0944 40 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 76786715 Common - BioY family protein SAK_0472 97 COG1268 BioY, Uncharacterized conserved protein General function prediction only 76787482 Common - prophage LambdaSa03, peptidoglycan endolysin SAK_0653 8 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 76787593 Common - hypothetical protein SAK_0958 12 COG4732 COG4732, Predicted membrane protein Function unknown 76786935 Common - Ser/Thr protein phosphatase family protein SAK_1364 112 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 76787078 Pathogen - hypothetical protein SAK_2027 1 None None None 76787964 Common - hypothetical protein SAK_0605 11 COG4698 COG4698, Uncharacterized protein conserved in bacteria Function unknown 76786770 Pathogen - hypothetical protein SAK_1857 1 None None None 76787526 Common - 4-carboxymuconolactone decarboxylase, putative SAK_0509 78 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 76787646 Common - hypothetical protein SAK_1124 7 COG4499 COG4499, Predicted membrane protein Function unknown 76787038 Common scrK fructokinase SAK_1701 28 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 76788234 Common cpsY transcriptional regulator CpsY SAK_1263 179 COG0583 LysR, Transcriptional regulator Transcription 76788309 Common ulaD 3-keto-L-gulonate-6-phosphate decarboxylase SAK_1832 49 COG0269 SgbH, 3-hexulose-6-phosphate synthase and related proteins Carbohydrate transport and metabolism 76788131 Common gid tRNA (uracil-5-)-methyltransferase Gid SAK_1064 192 COG1206 Gid, NAD(FAD)-utilizing enzyme possibly involved in translation Translation, ribosomal structure and biogenesis 76788111 Common - hypothetical protein SAK_0544 1 None None None 76787528 Common gatC aspartyl/glutamyl-tRNA amidotransferase subunit C SAK_1681 140 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 76786946 Common - polar amino acid uptake (PAAT) family ABC transporter, permease protein SAK_0363 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 76787386 Common - glucose uptake protein SAK_2115 11 COG4975 GlcU, Putative glucose uptake permease Carbohydrate transport and metabolism 76787654 Common - dihydroxyacetone kinase DAK1 domain protein SAK_1659 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 76788108 Common - permease, putative SAK_0172 71 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 76788504 Common - hydroxymethylglutaryl-CoA synthase SAK_1347 58 COG3425 PksG, 3-hydroxy-3-methylglutaryl CoA synthase Lipid metabolism 76788648 Common - hypothetical protein SAK_0553 3 None None None 76788639 Common - hypothetical protein SAK_0654 5 None None None 76787076 Common cylF cylF protein SAK_0798 102 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 76787471 Common glgC glucose-1-phosphate adenylyltransferase SAK_0977 222 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 76786898 Common - acetyltransferase, GNAT family SAK_0496 88 COG2153 ElaA, Predicted acyltransferase General function prediction only 76788294 Common atpG F0F1 ATP synthase subunit gamma SAK_0985 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 76787596 Common aroD 3-dehydroquinate dehydratase SAK_1412 48 COG0710 AroD, 3-dehydroquinate dehydratase Amino acid transport and metabolism 76787275 Common recA recombinase A SAK_2032 217 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 76787238 Common - hypothetical protein SAK_0740 8 None None None 76788523 Pathogen - hypothetical protein SAK_0294 1 None None None 76788418 Common alaS alanyl-tRNA synthetase SAK_0934 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 76788704 Common fusA elongation factor G SAK_1791 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 76788637 Pathogen - hypothetical protein SAK_1837 1 None None None 76788660 Common ribD riboflavin biosynthesis protein RibD SAK_0872 236 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 76788273 Common - universal stress family protein SAK_1741 97 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 76787467 Common - ISSag3, transposase SAK_0184 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 76788236 Common - hypothetical protein SAK_1309 67 COG1636 COG1636, Uncharacterized protein conserved in bacteria Function unknown 76788177 Common - methyltransferase, putative SAK_0554 212 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 76787713 Common rpoZ DNA-directed RNA polymerase subunit omega SAK_0384 14 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 76787422 Common - hypothetical protein SAK_0813 7 COG4529 COG4529, Uncharacterized protein conserved in bacteria Function unknown 76786751 Common uxaC glucuronate isomerase SAK_0827 59 COG1904 UxaC, Glucuronate isomerase Carbohydrate transport and metabolism 76787176 Common - polar amino acid uptake (PAAT) family ABC transporter, permease protein SAK_0842 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 76787882 Common - polar amino acid uptake (PAAT) family ABC transporter, ATP-binding protein SAK_0364 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 76788613 Pathogen - hypothetical protein SAK_0720 1 None None None 76788643 Common - amino acid ABC transporter, amino acid-binding/permease protein, His/Glu/Gln/Arg/opine family SAK_0194 177 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 76787740 Common - hypothetical protein SAK_0349 6 COG3711 BglG, Transcriptional antiterminator Transcription 76788499 Common priA primosome assembly protein PriA SAK_0385 213 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 76787223 Common - prophage Sa05, DNA primase, P4 family SAK_2083 39 COG3378 COG3378, Predicted ATPase General function prediction only 76787841 Common - glycine betaine/carnitine/choline ABC transporter, permease/substrate-binding protein SAK_2069 150 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 76787608 Common - transcriptional regulator, GntR family SAK_2012 68 COG2188 PhnF, Transcriptional regulators Transcription 76788677 Common ltaE low specificity L-threonine aldolase SAK_1778 64 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 76787396 Common recO DNA repair protein RecO SAK_0053 37 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 76786944 Common - lipoprotein, putative SAK_0883 3 None None None 76787002 Common - CvpA family protein SAK_1728 8 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 76787638 Common - carbohydrate kinase, FGGY family SAK_1823 174 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 76788707 Common xpt xanthine phosphoribosyltransferase SAK_1171 90 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 76788057 Common rplU 50S ribosomal protein L21 SAK_1403 119 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 76788361 Common - hypothetical protein SAK_1949 51 COG2378 COG2378, Predicted transcriptional regulator Transcription 76788696 Common - Ser/Thr protein phosphatase family protein SAK_0557 93 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 76787167 Common - ATP cone domain protein SAK_1140 56 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 76787199 Common - transferase, hexapeptide repeat family SAK_1029 189 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 76786984 Common fhs formate--tetrahydrofolate ligase SAK_1144 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 76787686 Common - phosphate ABC transporter, phosphate-binding protein SAK_1087 138 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 76786900 Common - hypothetical protein SAK_1683 111 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 76788482 Common - hypothetical protein SAK_0591 5 COG4703 COG4703, Uncharacterized protein conserved in bacteria Function unknown 76787674 Common dinB DNA polymerase IV SAK_1734 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 76788072 Common pyrB aspartate carbamoyltransferase catalytic subunit SAK_1134 236 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 76787615 Common - IS1381 transposase protein A SAK_2000 5 None None None 76787733 Common - cobalt ATP transporter, putative, ATP-binding protein SAK_2108 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 76787889 Common - transcriptional activator, Rgg/GadR/MutR family SAK_0298 6 None None None 76787817 Common - polar amino acid uptake (PAAT) family ABC transporter, permease protein SAK_1042 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 76786823 Common - RNA polymerase sigma-70 factor, ECF family SAK_0331 80 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 76787112 Pathogen - hypothetical protein SAK_1121 1 None None None 76786915 Common htpX heat shock protein HtpX SAK_1641 181 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 76787075 Common ffh signal recognition particle protein SAK_1077 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 76787327 Common - ABC transporter, ATP-binding protein SAK_0960 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 76786909 Common - hypothetical protein SAK_1787 4 COG4129 COG4129, Predicted membrane protein Function unknown 76788590 Common - hypothetical protein SAK_1616 13 COG3763 COG3763, Uncharacterized protein conserved in bacteria Function unknown 76787919 Common - hypothetical protein SAK_1965 4 None None None 76788196 Common - ABC transporter, ATP-binding/permease protein SAK_0562 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 76788373 Common glnR transcriptional regulator GlnR SAK_1786 42 COG0789 SoxR, Predicted transcriptional regulators Transcription 76787212 Pathogen - hypothetical protein SAK_0275 1 None None None 76788283 Common - immunogenic secreted protein, putative SAK_1695 9 COG3942 COG3942, Surface antigen General function prediction only 76787910 Common - DNA-binding response regulator SAK_1359 216 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 76788586 Common - hypothetical protein SAK_1367 3 COG3247 HdeD, Uncharacterized conserved protein Function unknown 76787347 Common - tRNA binding domain protein SAK_0244 194 COG0073 ARC1, EMAP domain General function prediction only 76788421 Common - hydrolase, NUDIX family SAK_1934 17 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 76786732 Common - hypothetical protein SAK_1465 10 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 76787231 Common ribF bifunctional riboflavin kinase/FMN adenylyltransferase SAK_1092 211 COG0196 RibF, FAD synthase Coenzyme metabolism 76787340 Common - PRD domain/PTS system IIA domain protein SAK_0259 50 COG3711 BglG, Transcriptional antiterminator Transcription 76787120 Common - hypothetical protein SAK_1928 3 COG2019 AdkA, Archaeal adenylate kinase Nucleotide transport and metabolism 76787032 Pathogen - DNA-binding protein SAK_0279 2 None None None 76788187 Common - FtsK/SpoIIIE family protein SAK_2056 14 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 76787773 Common - acetyltransferase, GNAT family SAK_2022 25 COG3981 COG3981, Predicted acetyltransferase General function prediction only 76788559 Common - acetoin reductase SAK_0674 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 76788653 Common - metallo-beta-lactamase family protein SAK_0847 59 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 76787864 Common - DNA replication protein DnaD, putative SAK_1291 20 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 76786854 Common - ABC transporter, ATP-binding protein, truncation SAK_1916 4 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 76786912 Common tsf elongation factor Ts SAK_1851 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 76787397 Common - polar amino acid uptake (PAAT) family ABC transporter, permease protein SAK_0592 175 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 76786809 Common - hypothetical protein SAK_1429 3 None None None 76787263 Common - alcohol dehydrogenase, zinc-containing SAK_1651 202 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 76788203 Common cinA competence damage-inducible protein A SAK_2033 212 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 76787929 Common - Sua5/YciO/YrdC/YwlC family protein SAK_1161 239 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 76787251 Common - peptidase, putative, M22 (O-sialoglycoprotein endopeptidase) family SAK_1781 181 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 76786724 Common - hypothetical protein SAK_0622 2 None None None 76787093 Common - DegV family protein SAK_0603 51 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 76787994 Common - hypothetical protein SAK_0995 87 COG2321 COG2321, Predicted metalloprotease General function prediction only 76786776 Common trkA potassium transporter peripheral membrane component SAK_1605 158 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 76787269 Common clpP ATP-dependent Clp protease proteolytic subunit SAK_1600 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 76786831 Common - sensor histidine kinase SAK_0468 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 76788598 Common punA purine nucleoside phosphorylase SAK_1267 118 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 76787542 Common - IS1381 transposase protein B SAK_1969 5 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 76786967 Common - metal ion transporter, CorA family SAK_0998 21 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 76788623 Common - IS1381 transposase protein A SAK_1970 5 None None None 76787412 Common - hypothetical protein SAK_1533 10 COG4479 COG4479, Uncharacterized protein conserved in bacteria Function unknown 76788494 Common stk1 serine/threonine protein kinase Stk1 SAK_0389 160 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 76788020 Common - bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein SAK_1987 177 COG0646 MetH, Methionine synthase I (cobalamin-dependent), methyltransferase domain Amino acid transport and metabolism 76787127 Common - Snf2 family protein SAK_1633 138 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 76787387 Common - copper transporter, copper-binding protein, putative SAK_0460 3 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 76788086 Pathogen - hypothetical protein SAK_2076 1 None None None 76787357 Common - ribonuclease BN, putative SAK_0970 26 COG1295 Rbn, Predicted membrane protein Function unknown 76788536 Common - polyprenyl synthetase family protein SAK_1746 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 76787443 Common pepV dipeptidase PepV SAK_1305 158 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 76787445 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 family protein SAK_0707 52 COG0546 Gph, Predicted phosphatases General function prediction only 76787761 Common gap glyceraldehyde-3-phosphate dehydrogenase SAK_1790 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 76788087 Common rgpAc rgpAc protein SAK_1458 28 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 76787085 Common - ABC transporter, ATP-binding protein SAK_1000 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 76787364 Pathogen - hypothetical protein SAK_0644 1 None None None 76786869 Common - acetyltransferase, GNAT family SAK_0441 57 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 76787824 Common rimM 16S rRNA-processing protein SAK_1386 106 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 76787826 Pathogen - Cna protein B-type domain SAK_0782 2 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 76788029 Common - penicillin-binding protein 1B SAK_0222 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 76788354 Common - prophage LambdaSa04, head-tail adaptor, putative SAK_0750 2 COG5614 COG5614, Bacteriophage head-tail adaptor General function prediction only 76788157 Pathogen - hypothetical protein SAK_1444 1 None None None 76787544 Common - glycosyl transferase, group 1 family protein SAK_0835 108 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 76787920 Common rpsN 30S ribosomal protein S14 SAK_0104 192 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 76787536 Common - plasmid replication protein SAK_2058 2 None None None 76788150 Common sufD FeS assembly protein SufD SAK_0200 184 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 76788244 Pathogen - hypothetical protein SAK_0237 1 None None None 76786767 Common - hypothetical protein SAK_0502 15 None None None 76787979 Common ruvA Holliday junction DNA helicase motor protein SAK_2035 209 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 76788522 Common - transcriptional regulator, LysR family SAK_1400 172 COG0583 LysR, Transcriptional regulator Transcription 76788319 Common - type IIG restriction enzyme and methyltransferase SAK_1333 57 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 76787101 Common - hypothetical protein SAK_1118 7 COG4495 COG4495, Uncharacterized protein conserved in bacteria Function unknown 76786774 Common - hypothetical protein SAK_1246 1 None None None 76787888 Common ung uracil-DNA glycosylase SAK_1245 129 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 76788099 Common fabD acyl-carrier-protein S-malonyltransferase SAK_0421 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 76787196 Common glnA glutamine synthetase, type I SAK_1785 230 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 76786850 Common - hypothetical protein SAK_1313 8 None None None 76787815 Common - DAK2 domain protein SAK_0182 50 COG1461 COG1461, Predicted kinase related to dihydroxyacetone kinase General function prediction only 76787578 Common rplI 50S ribosomal protein L9 SAK_2098 140 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 76788098 Common rpmD 50S ribosomal protein L30 SAK_0109 141 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 76787337 Common - hypothetical protein SAK_0935 48 COG1811 COG1811, Uncharacterized membrane protein, possible Na+ channel or pump General function prediction only 76786797 Common - hypothetical protein SAK_1212 122 COG2855 COG2855, Predicted membrane protein Function unknown 76787908 Common estA tributyrin esterase SAK_1272 33 COG0627 COG0627, Predicted esterase General function prediction only 76787108 Pathogen - hypothetical protein SAK_1745 1 None None None 76787314 Common pre plasmid recombination enzyme SAK_0286 40 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 76787832 Common - hypothetical protein SAK_0220 6 None None None 76786729 Common - putative translaldolase SAK_1757 174 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 76786789 Common ftsZ cell division protein FtsZ SAK_0581 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 76787977 Pathogen - hypothetical protein SAK_1117 1 None None None 76788448 Common rumA 23S rRNA (uracil-5-)-methyltransferase RumA SAK_0718 199 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 76788516 Common pyrG CTP synthetase SAK_0157 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 76787851 Common - LemA family protein SAK_1642 131 COG1704 LemA, Uncharacterized conserved protein Function unknown 76787407 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase SAK_0989 215 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 76786862 Pathogen - hypothetical protein SAK_0626 1 None None None 76788553 Common truB tRNA pseudouridine synthase B SAK_1093 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 76786720 Common nrdD anaerobic ribonucleoside triphosphate reductase SAK_2025 101 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 76787766 Common asp2 accessory secretory protein Asp2 SAK_1484 5 None None None 76787634 Common - LrgA family protein SAK_0250 35 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 76787420 Common purM phosphoribosylaminoimidazole synthetase SAK_0060 234 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 76788601 Common - sensor histidine kinase, putative SAK_2066 135 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76786857 Common valS valyl-tRNA synthetase SAK_0547 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 76788135 Common - hypothetical protein SAK_0469 8 COG5523 COG5523, Predicted integral membrane protein Function unknown 76786976 Common - hemolysin III SAK_1350 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 76788209 Common - conserved hypothetical protein TIGR01560 SAK_0749 2 None None None 76788413 Common - ABC transporter, ATP-binding/permease protein SAK_1157 237 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 76788189 Common - hypothetical protein SAK_1090 11 COG4476 COG4476, Uncharacterized protein conserved in bacteria Function unknown 76788101 Common - transcriptional regulator, Crp/Fnr family SAK_2119 84 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 76786953 Common - ABC transporter, permease protein SAK_0698 4 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 76788498 Common - aminotransferase, class V SAK_1406 238 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 76787557 Common gatA aspartyl/glutamyl-tRNA amidotransferase subunit A SAK_1680 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 76788007 Common - transcriptional regulator, putative SAK_0442 63 COG1316 LytR, Transcriptional regulator Transcription 76787945 Common - hypothetical protein SAK_1913 4 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 76787951 Pathogen - hypothetical protein SAK_1669 1 None None None 76787454 Common apt adenine phosphoribosyltransferase SAK_1292 187 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 76787791 Common - polar amino acid uptake (PAAT) family ABC transporter, ATP-binding protein SAK_0844 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 76787591 Common coaA pantothenate kinase SAK_1046 82 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 76787942 Common - DHH family protein SAK_2099 72 COG3887 COG3887, Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain Signal transduction mechanisms 76787565 Common cysS cysteinyl-tRNA synthetase SAK_0270 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 76788274 Common - DNA-binding protein SAK_2116 1 COG1395 COG1395, Predicted transcriptional regulator Transcription 76786983 Common accD acetyl-CoA carboxylase subunit beta SAK_0427 219 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 76787461 Common - hypothetical protein SAK_0372 11 COG4474 COG4474, Uncharacterized protein conserved in bacteria Function unknown 76786880 Common - CBS domain protein SAK_1593 167 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 76787607 Common - hypothetical protein SAK_0158 54 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 76788435 Common - bsp protein SAK_1381 4 None None None 76788143 Common - mannosyl-glycoprotein endo-beta-N-acetylglucosamidase family protein SAK_0144 48 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 76787200 Common phnA PhnA protein SAK_1041 106 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 76787400 Common - amidohydrolase family protein SAK_1824 9 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 76788709 Pathogen - hypothetical protein SAK_1947 1 None None None 76787017 Common cylB ABC transporter, permease protein CylB SAK_0796 11 None None None 76788326 Common lplA lipoate-protein ligase A SAK_1005 84 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 76788628 Pathogen - hypothetical protein SAK_0283 1 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 76787136 Common - MATE efflux family protein SAK_0089 114 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 76788006 Common secY preprotein translocase subunit SecY SAK_1486 220 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 76787416 Common - acetoin dehydrogenase, TPP-dependent, E1 component, beta subunit, putative SAK_1002 221 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 76788387 Common purD phosphoribosylamine--glycine ligase SAK_0076 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 76787204 Common gmk guanylate kinase SAK_0383 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 76787104 Common - acetyltransferase, GNAT family SAK_0545 131 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 76788517 Common - glucokinase, putative SAK_0573 158 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 76787756 Common mtsA metal ABC transporter, metal-binding lipoprotein SAK_1556 172 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 76787379 Common cylD CylD protein SAK_0791 5 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 76787004 Common - hypothetical protein SAK_1075 14 None None None 76788472 Common - replication initiation factor family protein SAK_1945 7 COG2946 COG2946, Putative phage replication protein RstA DNA replication, recombination, and repair 76787353 Pathogen - hypothetical protein SAK_0293 1 None None None 76787488 Common - hydrolasease, TatD family SAK_1804 239 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 76788534 Common - asparaginase family protein SAK_1691 138 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 76787538 Common - prophage LambdaSa04, site-specific recombinase, resolvase family SAK_0764 109 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 76788016 Common - hypothetical protein SAK_1297 3 COG4468 GalT, Galactose-1-phosphate uridyltransferase Carbohydrate transport and metabolism 76788349 Common - polysaccharide biosynthesis protein SAK_1447 45 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 76786764 Common rplC 50S ribosomal protein L3 SAK_0091 249 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 76788367 Common - beta-D-glucuronidase SAK_0824 72 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 76787728 Common pyrF orotidine 5'-phosphate decarboxylase SAK_1137 161 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 76787738 Common - sugar ABC transporter, sugar-binding protein, putative SAK_0532 115 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 76788218 Common carB carbamoyl phosphate synthase large subunit SAK_1132 236 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 76786885 Common dgkA diacylglycerol kinase SAK_1526 66 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 76787731 Common rgfC histidine kinase SAK_1917 10 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 76786878 Common carA carbamoyl phosphate synthase small subunit SAK_1396 237 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 76787184 Common thiE thiamine-phosphate pyrophosphorylase SAK_0965 192 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 76787133 Common - hypothetical protein SAK_1240 2 None None None 76788048 Common glpK glycerol kinase SAK_0345 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 76787783 Common - iron chelate uptake ABC transporter, ATP-binding protein SAK_1103 249 COG4604 CeuD, ABC-type enterochelin transport system, ATPase component Inorganic ion transport and metabolism 76787896 Common lspA signal peptidase II SAK_1399 134 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 76788269 Common map methionine aminopeptidase SAK_0969 241 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 76786962 Common pulA pullulanase, type I SAK_0975 145 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 76788115 Common rpsM 30S ribosomal protein S13 SAK_0114 241 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 76788113 Common - O-methyltransferase family protein SAK_0931 90 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 76787966 Common cydC ABC transporter, ATP-binding protein CydC SAK_1747 249 COG4987 CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 76788198 Common xpkA putative phosphoketolase SAK_1819 65 COG3957 COG3957, Phosphoketolase Carbohydrate transport and metabolism 76787644 Common - acetyltransferase, GNAT family SAK_1094 21 COG0456 RimI, Acetyltransferases General function prediction only 76786998 Common rmlC dTDP-4-keto-6-deoxyglucose-3,5-epimerase SAK_1286 155 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 76787052 Common - RelA/SpoT domain protein SAK_1360 35 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 76787114 Pathogen - prophage Sa05, transcriptional regulator, CopG family SAK_2088 1 None None None 76788133 Common - sugar transporter, putative SAK_0822 49 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 76787489 Common - drug:H+ antiporter-1 (DHA1) family protein SAK_1515 97 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 76787370 Common guaC guanosine 5'-monophosphate oxidoreductase SAK_1172 233 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 76788375 Common - nisin resistance protein Nsr, putative SAK_1068 29 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 76788604 Common - CHAP domain protein SAK_1784 4 COG3942 COG3942, Surface antigen General function prediction only 76787225 Pathogen - hypothetical protein SAK_2092 1 None None None 76788067 Common - ISSag8, transposase SAK_0941 56 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 76788053 Common secE preprotein translocase subunit SecE SAK_2003 2 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 76788458 Common - CRISPR-associated SAG0894 family protein SAK_1017 17 COG3513 COG3513, Uncharacterized protein conserved in bacteria Function unknown 76787778 Common nox NADH oxidase, water-forming SAK_1053 243 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 76788487 Common - prophage LambdaSa04, helicase, SNF2 family SAK_0733 77 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 76787143 Pathogen - hypothetical protein SAK_0281 1 None None None 76788672 Common glmU UDP-N-acetylglucosamine pyrophosphorylase SAK_1561 238 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 76787747 Common rpsC 30S ribosomal protein S3 SAK_0097 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 76786814 Common folA dihydrofolate reductase SAK_1345 146 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 76787179 Common - quaternary amine uptake (QAT) family ABC transporter, ATP-binding protein SAK_0303 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 76787255 Common - cation efflux transporter, cation diffusion facilitator (CDF) family SAK_0514 148 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 76788406 Common - PspC domain protein SAK_0860 4 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 76787871 Common - hypothetical protein SAK_1216 2 None None None 76787285 Common - transcriptional regulator, putative SAK_1948 27 COG1476 COG1476, Predicted transcriptional regulators Transcription 76787874 Common - KH domain/PhoH family protein SAK_1531 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 76787627 Common - low molecular weight phosphotyrosine protein phosphatase SAK_0083 113 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 76787302 Common - pyruvate formate-lyase-activating enzyme, putative SAK_0395 79 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 76787914 Common - IS10R, transposase SAK_2050 19 None None None 76786958 Common - rhomboid family protein SAK_0477 88 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 76787049 Common - prophage LambdaSa04, major capsid protein, HK97 family SAK_0748 59 COG4653 COG4653, Predicted phage phi-C31 gp36 major capsid-like protein General function prediction only 76787305 Common - sensor histidine kinase SAK_1921 223 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 76788686 Common - prophage LambdaSa04, RelE/ParE family protein SAK_0744 14 COG3668 ParE, Plasmid stabilization system protein General function prediction only 76787261 Pathogen - hypothetical protein SAK_0567 1 None None None 76787745 Common era GTP-binding protein Era SAK_1525 230 COG1159 Era, GTPase General function prediction only 76786917 Common serB phosphoserine phosphatase SerB SAK_0710 151 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 76786902 Common - maltose operon transcriptional repressor MalR, putative SAK_1474 128 COG1609 PurR, Transcriptional regulators Transcription 76787429 Common budA alpha-acetolactate decarboxylase SAK_1278 40 COG3527 AlsD, Alpha-acetolactate decarboxylase Secondary metabolites biosynthesis, transport, and catabolism 76787501 Common - glycosyl transferase, group 2 family protein SAK_0498 121 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 76786993 Common - transcriptional regulator, PadR family SAK_1972 21 COG1695 COG1695, Predicted transcriptional regulators Transcription 76788335 Common - peptidase, M16C (eupitrilysin) subfamily SAK_2111 184 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 76788694 Common - ABC transporter, ATP-binding protein SAK_0378 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 76788230 Common - DNA-binding response regulator, LuxR family SAK_0381 212 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 76788390 Common rpsQ 30S ribosomal protein S17 SAK_0100 221 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 76787786 Common - IS861, transposase orfB SAK_0505 143 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 76787601 Common - hypothetical protein SAK_1138 43 COG2966 COG2966, Uncharacterized conserved protein Function unknown 76786734 Common - transcriptional regulator, putative SAK_1660 14 COG1309 AcrR, Transcriptional regulator Transcription 76788369 Common - nitroreductase family protein SAK_1306 91 COG0778 NfnB, Nitroreductase Energy production and conversion 76787063 Common ptsI phosphoenolpyruvate-protein phosphotransferase SAK_0946 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 76787515 Pathogen - hypothetical protein SAK_1976 1 None None None 76787325 Pathogen - streptococcal histidine triad family protein SAK_1897 1 None None None 76787617 Common - hypothetical protein SAK_2028 15 COG3906 COG3906, Uncharacterized protein conserved in bacteria Function unknown 76788180 Common rplB 50S ribosomal protein L2 SAK_0094 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 76788646 Common rplX 50S ribosomal protein L24 SAK_0102 213 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 76787853 Common - hypothetical protein SAK_1129 8 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 76786819 Pathogen cpsH capsular polysaccharide synthesis protein CpsH SAK_1255 2 None None None 76788328 Common metG methionyl-tRNA synthetase SAK_1576 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 76788364 Common - ABC transporter, ATP-binding protein SAK_1975 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 76787277 Common aroK shikimate kinase SAK_0716 102 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 76788121 Common cylA ABC transporter, ATP-binding protein CylA SAK_0795 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 76787160 Common - hypothetical protein SAK_0443 1 None None None 76788541 Common - ISSag8, transposase SAK_0564 56 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 76787789 Common cycA D-Serine/D-alanine/glycine:H+ symporter SAK_1510 139 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 76787236 Common - transcriptional regulator, putative SAK_0717 44 COG1316 LytR, Transcriptional regulator Transcription 76788262 Common - hypothetical protein SAK_0225 5 COG4699 COG4699, Uncharacterized protein conserved in bacteria Function unknown 76788416 Common lepA GTP-binding protein LepA SAK_1022 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 76788571 Common - enoyl-CoA hydratase SAK_0416 118 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 76787594 Common - hypothetical protein SAK_0322 2 None None None 76788480 Common - acetyltransferase, GNAT family SAK_1569 29 COG0456 RimI, Acetyltransferases General function prediction only 76788456 Common - oxidoreductase, Gfo/Idh/MocA family SAK_1564 166 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 76787495 Common nikE nickel ABC transporter, ATP-binding protein SAK_1538 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 76787178 Common - redox-sensing transcriptional repressor Rex SAK_1185 56 COG2344 COG2344, AT-rich DNA-binding protein General function prediction only 76787828 Pathogen - hypothetical protein SAK_0690 1 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 76788635 Common - CAAX amino terminal protease family protein SAK_1496 38 None None None 76788386 Pathogen - streptococcal histidine triad family protein SAK_1318 1 None None None 76786923 Common - prophage LambdaSa04, DNA polymerase SAK_0725 159 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 76788340 Common - 3H domain protein SAK_1618 15 COG1827 COG1827, Predicted small molecule binding protein (contains 3H domain) General function prediction only 76788079 Common - DNA-binding response regulator SAK_1992 226 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 76787394 Common nusB transcription antitermination protein NusB SAK_1705 191 COG0781 NusB, Transcription termination factor Transcription 76788641 Common rpsF 30S ribosomal protein S6 SAK_1722 189 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 76788550 Pathogen - hypothetical protein SAK_0351 1 None None None 76788239 Common - acetoin dehydrogenase, TPP-dependent, E3 component, dihydrolipoamide dehydrogenase, putative SAK_1004 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 76787996 Common accA acetyl-CoA carboxylase subunit alpha SAK_0428 175 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 76788041 Common radC DNA repair protein RadC SAK_1186 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 76787586 Common - hypothetical protein SAK_1562 36 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 76787692 Common pepDA dipeptidase A SAK_0684 25 COG4690 PepD, Dipeptidase Amino acid transport and metabolism 76788492 Common - aldehyde dehydrogenase family protein SAK_1211 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 76788399 Common gor glutathione reductase SAK_1408 245 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 76788611 Common - hypothetical protein SAK_1959 2 None None None 76788395 Common - hypothetical protein SAK_1225 2 None None None 76788050 Common tilS tRNA(Ile)-lysidine synthetase SAK_0013 210 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 76788596 Common - prophage LambdaSa04, site-specific recombinase, resolvase family SAK_0763 75 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 76787540 Common mmuM homocysteine methyltransferase SAK_1337 156 COG2040 MHT1, Homocysteine/selenocysteine methylase (S-methylmethionine-dependent) Amino acid transport and metabolism 76787662 Common - major facilitator family protein SAK_0927 123 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 76786765 Common - hypothetical protein SAK_1469 109 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 76787083 Common - ABC transporter, permease protein, carbohydrate uptake 2 (CUT2) family, putative SAK_1052 140 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 76787359 Common - glycerol facilitator/aquaporin SAK_1740 132 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 76787477 Common - DNA-binding response regulator SAK_1071 218 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 76788175 Common uxuA mannonate dehydratase SAK_0828 58 COG1312 UxuA, D-mannonate dehydratase Carbohydrate transport and metabolism 76787681 Common nagB glucosamine-6-phosphate isomerase SAK_0924 83 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 76787763 Common hsdM type I restriction-modification system, M subunit SAK_1754 161 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 76788084 Common - hypothetical protein SAK_2113 34 COG2501 COG2501, Uncharacterized conserved protein Function unknown 76788565 Common - ABC transporter, ATP-binding protein SAK_0334 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 76788313 Common - hypothetical protein SAK_0520 4 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 76787549 Common neuB N-acetyl neuramic acid synthetase NeuB SAK_1250 78 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 76787243 Common gldA glycerol dehydrogenase SAK_0403 147 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 76787073 Common - conserved hypothetical protein TIGR00257 SAK_0405 134 COG1739 COG1739, Uncharacterized conserved protein Function unknown 76786896 Common - adenylate cyclase, putative SAK_1181 9 COG4116 COG4116, Uncharacterized protein conserved in bacteria Function unknown 76787521 Common asnC asparaginyl-tRNA synthetase SAK_0677 249 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 76786924 Common efp elongation factor P SAK_1707 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 76787447 Common - ISSag5, transposase orfB SAK_0772 147 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 76788027 Common pfs 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase SAK_1558 88 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 76788356 Common dnaI primosomal protein DnaI SAK_1635 39 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 76787917 Common - IS1381 transposase protein A SAK_1060 5 None None None 76787247 Common hrcA heat-inducible transcription repressor SAK_0145 144 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 76788155 Common cmk cytidylate kinase SAK_1418 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 76787217 Common - S4 domain protein SAK_0585 32 COG2302 COG2302, Uncharacterized conserved protein, contains S4-like domain Function unknown 76787939 Common rpmC 50S ribosomal protein L29 SAK_0099 19 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 76787293 Common folP dihydropteroate synthase SAK_1200 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 76787648 Common - hypothetical protein SAK_1187 167 COG0628 PerM, Predicted permease General function prediction only 76788584 Common - hypothetical protein SAK_1986 44 COG4420 COG4420, Predicted membrane protein Function unknown 76787380 Common comGA competence protein ComGA SAK_0226 205 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 76787034 Common - hypothetical protein SAK_1620 11 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 76788204 Common ileS isoleucyl-tRNA synthetase SAK_0587 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 76788529 Common mutM formamidopyrimidine-DNA glycosylase SAK_1519 182 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 76787688 Common - sensor histidine kinase SAK_2062 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76787984 Common serS seryl-tRNA synthetase SAK_0430 246 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 76788246 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 family protein SAK_0930 88 COG0546 Gph, Predicted phosphatases General function prediction only 76788655 Common - hypothetical protein SAK_1325 5 None None None 76787346 Common ruvB Holliday junction DNA helicase B SAK_0082 225 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 76787389 Pathogen - lipoprotein, putative SAK_0137 1 None None None 76788478 Common hpt hypoxanthine-guanine phosphoribosyltransferase SAK_0014 154 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 76786932 Common - hypothetical protein SAK_1330 3 None None None 76787568 Common - hypothetical protein SAK_0854 7 COG3689 COG3689, Predicted membrane protein Function unknown 76787253 Pathogen - hypothetical protein SAK_1941 1 None None None 76788090 Common lacB galactose-6-phosphate isomerase subunit LacB SAK_1889 127 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 76786864 Common - cardiolipin synthase, putative SAK_1143 142 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 76787711 Common gpmA phosphoglyceromutase SAK_0889 157 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 76786804 Common - hypothetical protein SAK_0431 7 COG3274 COG3274, Uncharacterized protein conserved in bacteria Function unknown 76788258 Common - hypothetical protein SAK_1492 9 None None None 76786786 Common - hypothetical protein SAK_1524 1 None None None 76788217 Common rpsP 30S ribosomal protein S16 SAK_1391 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 76787676 Common - transcriptional regulator, MerR family SAK_1667 33 COG0789 SoxR, Predicted transcriptional regulators Transcription 76786965 Common clpX ATP-dependent protease ATP-binding subunit SAK_1343 225 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 76787095 Common rexB exonuclease RexB SAK_0996 32 COG3857 AddB, ATP-dependent nuclease, subunit B DNA replication, recombination, and repair 76788038 Pathogen - hypothetical protein SAK_2054 1 None None None 76787054 Common - radical SAM enzyme, Cfr family SAK_0559 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 76786951 Common lacA galactose-6-phosphate isomerase subunit LacA SAK_1890 124 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 76788485 Common - acetyltransferase, GNAT family SAK_0967 67 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 76787332 Common rpoE DNA-directed RNA polymerase subunit delta SAK_0156 12 COG3343 RpoE, DNA-directed RNA polymerase, delta subunit Transcription 76787961 Common thyA thymidylate synthase SAK_1346 135 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 76786942 Common - capA domain protein SAK_1404 52 COG2843 PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) Cell envelope biogenesis, outer membrane 76788687 Common - acyl carrier protein phosphodiesterase, putative SAK_0341 79 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 76788674 Common - Cof-like hydrolase family protein SAK_1690 128 COG4696 COG4696, Uncharacterized protein conserved in bacteria Function unknown 76787410 Pathogen - hypothetical protein SAK_0627 1 None None None 76787366 Common - hypothetical protein SAK_0681 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 76788076 Common - hypothetical protein SAK_1755 4 None None None 76787517 Common - prophage LambdaSa03, transcriptional regulator, Cro/CI family SAK_0611 4 COG1396 HipB, Predicted transcriptional regulators Transcription 76787629 Pathogen - hypothetical protein SAK_2087 1 None None None 76787259 Common - CHY zinc finger family protein SAK_0471 14 COG4357 COG4357, Uncharacterized conserved protein Function unknown 76787940 Common - cell wall surface anchor family protein SAK_0777 9 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 76787026 Common - transcriptional regulator, MarR family SAK_0417 81 COG1846 MarR, Transcriptional regulators Transcription 76788640 Pathogen - hypothetical protein SAK_0508 1 None None None 76787683 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 family protein SAK_0415 167 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 76788000 Common - hypothetical protein SAK_0330 6 None None None 76787043 Common - PTS system, IIA component, mannose/fructose/sorbose family SAK_1911 7 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 76787704 Common - ABC transporter, ATP-binding/permease protein SAK_1368 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 76786970 Common hexA DNA mismatch repair protein SAK_2040 205 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 76788547 Common metE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase SAK_1988 141 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 76788343 Common - nucleotide sugar dehydratase, putative SAK_1451 224 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 76788231 Common - hypothetical protein SAK_0920 5 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 76786736 Pathogen - hypothetical protein SAK_1661 1 None None None 76787307 Common - geranyltranstransferase SAK_0599 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 76786979 Pathogen - hypothetical protein SAK_0507 1 None None None 76787202 Common - hypothetical protein SAK_1580 10 COG4814 COG4814, Uncharacterized protein with an alpha/beta hydrolase fold General function prediction only 76787417 Common - transglycosylase-like domain protein SAK_2105 4 None None None 76787531 Pathogen - hypothetical protein SAK_1769 1 None None None 76787643 Common - hypothetical protein SAK_1480 3 None None None 76788447 Common proWX glycine betaine/proline ABC transporter, permease/substrate-binding protein SAK_1817 177 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 76786794 Common - topology modulation protein SAK_1984 41 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 76788163 Common leuS leucyl-tRNA synthetase SAK_1995 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 76788446 Common - hypothetical protein SAK_0390 9 COG4758 COG4758, Predicted membrane protein Function unknown 76788281 Common rplF 50S ribosomal protein L6 SAK_0106 230 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 76787209 Common - cobalt ABC transporter, permease protein SAK_2107 79 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 76787724 Common - hypothetical protein SAK_1290 32 COG2384 COG2384, Predicted SAM-dependent methyltransferase General function prediction only 76787351 Common - hypothetical protein SAK_0769 23 COG4283 COG4283, Uncharacterized conserved protein Function unknown 76787434 Common - prophage LambdaSa03, minor structural protein, putative SAK_0648 2 None None None 76788597 Common - rhodanese-like domain protein SAK_1982 153 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 76787968 Pathogen - prophage Sa05, DNA-binding protein SAK_2091 1 COG1476 COG1476, Predicted transcriptional regulators Transcription 76787186 Common glyS glycyl-tRNA synthetase subunit beta SAK_0342 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 76787936 Common - hypothetical protein SAK_0808 22 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 76787990 Common - hypothetical protein SAK_0230 2 None None None 76788645 Common - hypothetical protein SAK_1383 15 COG3641 PfoR, Predicted membrane protein, putative toxin regulator General function prediction only 76788401 Common - hypothetical protein SAK_0506 16 COG3708 COG3708, Uncharacterized protein conserved in bacteria Function unknown 76787898 Common cpsF polysaccharide biosynthesis protein CpsF SAK_1257 17 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 76786719 Common - SPFH domain/band 7 family protein SAK_0183 182 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 76788014 Common msrB methionine sulfoxide reductase B SAK_1026 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 76788035 Common - permease, amino acid-polyamine-organocation (APC) family SAK_1604 157 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 76788118 Common - membrane protein, MarC family SAK_2101 157 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 76788483 Common cpsB protein-tyrosine phosphatase CpsB SAK_1261 37 COG4464 CapC, Capsular polysaccharide biosynthesis protein Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 76788183 Common - uracil DNA glycosylase family protein SAK_1304 56 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 76787486 Common rumA 23S rRNA (uracil-5-)-methyltransferase RumA SAK_0494 197 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 76787567 Common - ISSag8, transposase SAK_0671 55 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 76787014 Pathogen - hypothetical protein SAK_0802 1 None None None 76786996 Common - mur ligase family protein SAK_1007 60 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 76786833 Common - cupin domain protein SAK_0510 67 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 76787797 Common - acetyltransferase, GNAT family SAK_1585 16 None None None 76788055 Common - mechanosensitive ion channel family protein SAK_0154 95 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 76788069 Common - LysM domain protein SAK_2106 11 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 76786758 Common - hypothetical protein SAK_0438 18 COG4330 COG4330, Predicted membrane protein Function unknown 76788578 Pathogen - aldose 1-epimerase, interruption-C SAK_0542 1 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 76787690 Common - glycosyl hydrolase, family 25 SAK_0881 8 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 76787972 Pathogen - fibrinogen-binding protein SAK_0955 2 None None None 161486744 Common obgE GTPase ObgE SAK_1500 249 COG0536 Obg, Predicted GTPase General function prediction only 76788060 Common araD L-ribulose-5-phosphate 4-epimerase SAK_1830 136 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 76787426 Pathogen - hypothetical protein SAK_0445 1 None None None 76788298 Common - hypothetical protein SAK_1374 5 COG4835 COG4835, Uncharacterized protein conserved in bacteria Function unknown 76786844 Common - hypothetical protein SAK_1654 185 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 76788427 Common - ABC transporter, permease protein SAK_0534 158 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 76788222 Common - exonuclease, DNA polymerase III, epsilon subunit family SAK_1324 179 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 76786825 Common - hypothetical protein SAK_0705 1 None None None 76787289 Common - hypothetical protein SAK_1974 9 None None None 76787772 Common - prophage LambdaSa04, portal protein, HK97 family SAK_0746 70 COG4695 COG4695, Phage-related protein Function unknown 76788278 Common - RNA methyltransferase, TrmH family SAK_1621 208 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 76788532 Common - glycerol-3-phosphate transporter, putative SAK_1471 66 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 76788434 Common - lipoprotein, NLPA family SAK_1655 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 76787463 Common thiD phosphomethylpyrimidine kinase SAK_0963 220 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 76788567 Common - glycosyl transferase, group 1 family protein SAK_1481 168 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 76787559 Common - arginine repressor, putative SAK_2118 56 COG1438 ArgR, Arginine repressor Transcription 76788306 Common - permease, putative SAK_0810 46 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 76787550 Common - major facilitator family protein SAK_1742 180 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 76787726 Common adcC zinc ABC transporter, ATP-binding protein SAK_0218 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 76787452 Common - hypothetical protein SAK_0911 145 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 76788229 Common deoB phosphopentomutase SAK_2008 70 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 76787156 Common uraA uracil permease SAK_1230 122 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 76788582 Common ribE 6,7-dimethyl-8-ribityllumazine synthase SAK_0875 230 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 76787659 Common - PTS system, IIC component, mannose/fructose/sorbose family SAK_0434 35 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 76788342 Common rpoD RNA polymerase sigma factor RpoD SAK_1461 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 76788508 Common - LrgB family protein SAK_1234 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 76787811 Common - sensor histidine kinase SAK_1072 115 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76787402 Common fabF 3-oxoacyl-(acyl carrier protein) synthase II SAK_0423 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 76788145 Common satD satD protein SAK_1076 4 None None None 76788327 Common - DivIVA domain protein SAK_0373 16 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 76788136 Common dnaE DNA polymerase III DnaE SAK_1035 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 76787194 Common - lrgB-like family protien SAK_0251 81 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 76787576 Common - DNA-binding response regulator SAK_0189 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 76787072 Common - cell wall surface anchor family protein SAK_0776 11 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 76787409 Common - deoxynucleoside kinase family protein SAK_1846 39 COG1428 COG1428, Deoxynucleoside kinases Nucleotide transport and metabolism 76787809 Common secY preprotein translocase subunit SecY SAK_0111 217 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 76787813 Common - hypothetical protein SAK_2030 24 COG4472 COG4472, Uncharacterized protein conserved in bacteria Function unknown 76787835 Common - hypothetical protein SAK_0071 9 COG5578 COG5578, Predicted integral membrane protein Function unknown 76787170 Common rfbD dTDP-4-dehydrorhamnose reductase SAK_1459 186 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 76788404 Pathogen - hypothetical protein SAK_0612 1 None None None 76786863 Common - carbohydrate uptake 1 (CUT1) family ABC transporter, permease protein SAK_0068 139 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 76787602 Common udp uridine phosphorylase SAK_2011 100 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 76787779 Pathogen - hypothetical protein SAK_1067 1 None None None 76787906 Common - phosphoglycerate mutase family protein SAK_0142 42 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 76787315 Common - transglycosylase associated protein SAK_1226 12 COG2261 COG2261, Predicted membrane protein Function unknown 76786957 Common pheT phenylalanyl-tRNA synthetase subunit beta SAK_0994 247 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 76788026 Common - prophage LambdaSa04, terminase, large subunit SAK_0742 46 COG4626 COG4626, Phage terminase-like protein, large subunit General function prediction only 76787560 Common tag DNA-3-methyladenine glycosylase I SAK_2034 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 76786820 Common - hypothetical protein SAK_1151 15 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 76787800 Pathogen - hypothetical protein SAK_1955 1 None None None 76788514 Common - oxidoreductase, aldo/keto reductase family SAK_1506 195 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 76787632 Common nikD nickel ABC transporter, ATP-binding protein SAK_1539 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 76786744 Common - metallo-beta-lactamase family protein SAK_0673 197 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 76786723 Common - MagZ family protein SAK_1979 8 COG1694 MazG, Predicted pyrophosphatase General function prediction only 76787790 Common - ribosomal large subunit pseudouridine synthase, RluA family SAK_1398 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 76788334 Pathogen - hypothetical protein SAK_0990 1 None None None 76788091 Common rbfA ribosome-binding factor A SAK_0456 147 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 76787316 Common - hypothetical protein SAK_0620 2 None None None 76787131 Common - hypothetical protein SAK_1572 11 COG5337 CotH, Spore coat assembly protein Cell envelope biogenesis, outer membrane 76787344 Common - Cof-like hydrolase SAK_0462 142 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 76787821 Common - plasmid replication protein SAK_1327 3 None None None 76787847 Common rexA exonuclease RexA SAK_0997 228 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 76787933 Pathogen - hypothetical protein SAK_1113 1 None None None 76787142 Common - major facilitator family transporter SAK_0299 127 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 76788659 Common recX recombination regulator RecX SAK_0493 34 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 76788125 Pathogen - hypothetical protein SAK_1344 1 None None None 76788260 Common nusA transcription elongation factor NusA SAK_0452 223 COG0195 NusA, Transcription elongation factor Transcription 76787341 Common - DNA-binding response regulator SAK_0838 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 76787926 Common ppc phosphoenolpyruvate carboxylase SAK_0885 116 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 76788650 Common - PTS system, IIB component, putative SAK_1894 4 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 76788366 Pathogen - hypothetical protein SAK_0192 1 None None None 76787284 Common - hypothetical protein SAK_0267 2 None None None 76788287 Common - PTS system, IIC component, mannose/fructose/sorbose family SAK_1909 36 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 76787498 Common - hypothetical protein SAK_0583 32 COG1799 COG1799, Uncharacterized protein conserved in bacteria Function unknown 76787652 Common rpsS 30S ribosomal protein S19 SAK_0095 243 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 76787735 Common rplM 50S ribosomal protein L13 SAK_0276 217 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 76788256 Pathogen - hypothetical protein SAK_0805 1 None None None 76788054 Common scpA segregation and condensation protein A SAK_1610 146 COG1354 COG1354, Uncharacterized conserved protein Function unknown 76788207 Common - ROK family protein SAK_0073 120 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 76787173 Common - hypothetical protein SAK_0636 2 None None None 76787588 Common - hypothetical protein SAK_0377 76 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 76787860 Common - hypothetical protein SAK_1376 5 COG4331 COG4331, Predicted membrane protein Function unknown 76788043 Common ychF translation-associated GTPase SAK_0006 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 76787126 Common rpiA ribose-5-phosphate isomerase A SAK_1270 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 76787360 Common - L-2-hydroxyisocaproate dehydrogenase SAK_0179 146 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 76788618 Pathogen - prophage Sa05, transcriptional regulator, ArpU family SAK_2079 1 None None None 76787562 Common - transcriptional regulator, AraC family SAK_0531 149 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 76787123 Common eutD phosphotransacetylase SAK_1177 167 COG0280 Pta, Phosphotransacetylase Energy production and conversion 76788657 Common - IS1381 transposase protein B SAK_1208 5 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 76787679 Common rplO 50S ribosomal protein L15 SAK_0110 216 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 76788034 Common - hypothetical protein SAK_1865 7 None None None 76786939 Common - DNA-binding protein SAK_0235 64 COG1476 COG1476, Predicted transcriptional regulators Transcription 76787428 Common - Cof-like hydrolase/peptidyl-prolyl cis-trans isomerase domain protein SAK_0393 217 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 76788082 Common - hypothetical protein SAK_0522 149 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 76787476 Common - ribonucleotide-diphosphate reductase subunit alpha SAK_0943 216 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 76786930 Common mtsB metal ABC transporter, ATP-binding protein SAK_1555 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 76786762 Common - peptidase, S8 (subtilisin) family SAK_0804 40 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 76787440 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase SAK_0480 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 76787717 Common - aldose 1-epimerase, interruption-N SAK_0539 88 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 76786836 Common - CAAX amino terminal protease family protein SAK_1523 2 None None None 76788154 Common - hypothetical protein SAK_1454 2 None None None 76787867 Common - NADPH-dependent FMN reductase domain protein SAK_1167 104 COG0431 COG0431, Predicted flavoprotein General function prediction only 76788192 Common hprK HPr kinase/phosphorylase SAK_0862 76 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 76788210 Common - hypothetical protein SAK_1244 170 COG0344 COG0344, Predicted membrane protein Function unknown 76786968 Common - hypothetical protein SAK_1574 15 None None None 76788311 Common - rRNA (guanine-N1-) methyltransferase (Mycinamicin-resistance protein) SAK_1800 54 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 76787743 Common luxS S-ribosylhomocysteinase SAK_0376 55 COG1854 LuxS, LuxS protein involved in autoinducer AI2 synthesis Signal transduction mechanisms 76786963 Common - glutamine amidotransferase SAK_0563 240 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 76788473 Common xerD site-specific tyrosine recombinase XerD-like protein SAK_1611 2 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 76787449 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase SAK_0922 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 76786805 Common aphA acid phosphatase/phosphotransferase SAK_0768 12 COG3700 AphA, Acid phosphatase (class B) General function prediction only 76787667 Common pflB formate acetyltransferase 1 SAK_1735 56 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 76788240 Common - ErfK/YbiS/YcfS/YnhG family protein SAK_1109 15 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 76786876 Common - ISSag9, transposase SAK_1545 39 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 76787249 Common - azaleucine resistance protein AzlD, putative SAK_1989 13 COG4392 COG4392, Predicted membrane protein Function unknown 76787547 Common - recombination factor protein RarA SAK_1938 242 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 76787953 Common - hypothetical protein SAK_0343 17 COG4224 COG4224, Uncharacterized protein conserved in bacteria Function unknown 76788083 Common prsA foldase protein PrsA SAK_0932 18 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 76787089 Common - monovalent cation:proton antiporter-1 (CPA1) family protein SAK_1856 101 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 76787116 Common - alpha-galactosidase, putative SAK_0535 44 COG3345 GalA, Alpha-galactosidase Carbohydrate transport and metabolism 76788521 Common - alkaline shock protein 23, putative SAK_1223 32 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 76788666 Common - transcriptional regulator, MerR family SAK_1772 112 COG0789 SoxR, Predicted transcriptional regulators Transcription 76787245 Common - hypothetical protein SAK_1407 1 None None None 76786893 Common - ABC transporter, ATP-binding protein SAK_1966 27 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 76788277 Common recU Holliday junction-specific endonuclease SAK_0371 17 COG3331 PrfA, Penicillin-binding protein-related factor A, putative recombinase General function prediction only 76788595 Common - acetyltransferase, GNAT family SAK_0327 86 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 76788453 Pathogen - hypothetical protein SAK_0138 1 None None None 76787080 Common spxA transcriptional regulator Spx SAK_1091 72 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 76788388 Common ccpA catabolite control protein A SAK_0833 128 COG1609 PurR, Transcriptional regulators Transcription 76787622 Common cpsC capsular polysaccharide biosynthesis protein cpsC SAK_1260 32 COG3944 COG3944, Capsular polysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 76786926 Common - peptide/opine/nickel uptake (PepT) family ABC transporter, substrate-binding protein SAK_0252 202 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 76788123 Pathogen - hypothetical protein SAK_0650 1 None None None 76788174 Common - FemAB family protein SAK_0660 21 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 76787986 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase SAK_0577 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 76787415 Common - thiamine pyrophosphokinase SAK_1797 32 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 76786865 Common - hypothetical protein SAK_1607 185 COG0759 COG0759, Uncharacterized conserved protein Function unknown 76787069 Common dltD dltD protein SAK_1809 12 COG3966 DltD, Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) Cell envelope biogenesis, outer membrane 76787105 Common ylxR cytosolic protein YlxR SAK_0453 32 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 76787097 Common - hypothetical protein SAK_0551 13 COG2315 MmcQ, Uncharacterized protein conserved in bacteria Function unknown 76787573 Common rdgB putative deoxyribonucleotide triphosphate pyrophosphatase/unknown domain fusion protein SAK_1614 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 76786755 Common - ISSag9, transposase SAK_0164 39 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 76788633 Pathogen - hypothetical protein SAK_1805 1 None None None 76788693 Common - prophage LambdaSa03, minor structural protein, putative SAK_0647 14 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 76788397 Common pstC phosphate ABC transporter, permease protein PstC SAK_1086 227 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 76788616 Common - phospho-2-dehydro-3-heoxyheptonate aldolase SAK_1698 110 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 76787392 Common - pencillin-binding protein, 1A family SAK_0370 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 76788350 Common - hypothetical protein SAK_1349 7 None None None 76788219 Common - cna B-type domain protein SAK_0780 7 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 76786845 Common cas1 CRISPR-associated protein Cas1 SAK_1018 39 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 76787787 Common coaE dephospho-CoA kinase SAK_1518 208 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 76788393 Common - phosphosugar-binding transcriptional regulator, RpiR family SAK_0075 93 COG1737 RpiR, Transcriptional regulators Transcription 76788331 Common - hypothetical protein SAK_1631 1 None None None 76787767 Common - HD domain protein SAK_1795 46 COG3481 COG3481, Predicted HD-superfamily hydrolase General function prediction only 76787583 Common - glyoxalase family protein SAK_1563 7 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 76786919 Common - tellurite resistance protein TehB SAK_1577 29 COG3615 TehB, Uncharacterized protein/domain, possibly involved in tellurite resistance Inorganic ion transport and metabolism 76787271 Common - citrate, cation symporter (CCS) family protein SAK_1879 30 COG3493 CitS, Na+/citrate symporter Energy production and conversion 76787163 Common - hypothetical protein SAK_2053 2 None None None 76788078 Common - hypothetical protein SAK_1499 2 None None None 76787506 Common - aldehyde-alcohol dehydrogenase SAK_0086 190 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 76786886 Common rpsI 30S ribosomal protein S9 SAK_0277 246 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 76786731 Common - FmtC protein, putative SAK_2070 66 COG2898 COG2898, Uncharacterized conserved protein Function unknown 76788624 Pathogen - hypothetical protein SAK_1116 1 None None None 76788009 Common - competence protein ComFA, putative SAK_0406 110 COG4098 comFA, Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein) DNA replication, recombination, and repair 76788424 Common trxB thioredoxin-disulfide reductase SAK_0366 249 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 76788555 Common rfbB dTDP-glucose 4,6-dehydratase SAK_1285 231 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 76788464 Common - hypothetical protein SAK_1782 11 COG5503 COG5503, Uncharacterized conserved small protein Function unknown 76787670 Common - ABC transporter, ATP-binding protein SAK_0352 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 76787323 Pathogen - lipoprotein, putative SAK_0269 1 None None None 76787006 Pathogen - hypothetical protein SAK_0005 1 None None None 76786905 Common - prophage LambdaSa04, DNA methylase SAK_0738 107 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 76787060 Common - Cof-like hydrolase SAK_0436 112 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 76787855 Common - pyridine nucleotide-disulfide oxidoreductase SAK_0163 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 76786972 Common - D-alanyl-D-alanine carboxypeptidase SAK_0143 31 COG1876 VanY, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 76787215 Common - 1,4-dihydroxy-2-naphthoate octaprenyltransferase SAK_1752 42 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 76786792 Common phoU phosphate transport system regulatory protein PhoU SAK_1923 196 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 76787837 Common - major facilitator family protein SAK_1546 199 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 76787118 Common dnaX DNA polymerase III subunits gamma and tau SAK_0952 247 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 76787641 Common - CoA binding domain protein SAK_0464 124 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 76787240 Common - prophage LambdaSa04, ClpP endopeptidase (S14) family, non-peptidase homologue, putative SAK_0747 187 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 76787992 Common - CAAX amino terminal protease family protein SAK_0054 24 None None None 76787419 Common - prophage LambdaSa04, minor structural protein SAK_0758 6 COG4926 PblB, Phage-related protein Function unknown 76788161 Common glmM phosphoglucosamine mutase SAK_1010 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 76787510 Common - branched-chain alpha-keto acid dehydrogenase subunit E2 SAK_1003 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 76787722 Pathogen - hypothetical protein SAK_1438 1 None None None 76788391 Common - HD domain protein SAK_1673 44 COG1713 COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism Coenzyme metabolism 76788631 Common - IS1381 transposase protein B SAK_0190 5 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 76788307 Common glgD glucose-1-phosphate adenylyltransferase, GlgD subunit SAK_0978 120 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 76787207 Common fhuB ferrichrome ABC transporter, permease protein SAK_1427 190 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 76787436 Common - acetyltransferase, GNAT family SAK_1370 55 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 76786908 Common - hypothetical protein SAK_0451 133 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 76787438 Common - sortase family protein SAK_1056 23 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 76788226 Pathogen - hypothetical protein SAK_0624 1 None None None 76788476 Common nrdF ribonucleotide-diphosphate reductase subunit beta SAK_0499 60 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 76787752 Common metK S-adenosylmethionine synthetase SAK_0736 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 76786772 Common cstA carbon starvation protein CstA SAK_1110 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 76787963 Common yfiA ribosomal subunit interface protein SAK_0408 171 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 76787891 Common guaB inositol-5-monophosphate dehydrogenase SAK_2117 240 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 76787458 Common - pneumococcal vaccine antigen A, putative SAK_1158 8 None None None 76786881 Common ppnK inorganic polyphosphate/ATP-NAD kinase SAK_1179 238 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 76787923 Common - diacylglycerol kinase domain protein SAK_0003 59 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 76787375 Common - cyclic nucleotide-binding domain protein SAK_1862 24 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 76788215 Common - iron-sulfur cluster-binding protein, putative SAK_0667 138 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 76788468 Common - hypothetical protein SAK_2024 2 None None None 76788608 Common - formate/nitrite transporter family protein SAK_1169 69 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 76787893 Common - hypothetical protein SAK_1946 2 None None None 76787188 Common - metallo-beta-lactamase family protein SAK_1783 160 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 76788493 Pathogen - hypothetical protein SAK_0185 1 None None None 76788012 Common prs ribose-phosphate pyrophosphokinase SAK_1182 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 76787818 Common - hypothetical protein SAK_0382 7 COG3548 COG3548, Predicted integral membrane protein Function unknown 76786994 Pathogen - hypothetical protein SAK_1914 1 None None None 76788605 Common - PTS system, glucose-specific IIABC component, putative SAK_1920 59 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 76786897 Common hom homoserine dehydrogenase SAK_1205 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 76787483 Common - glycerophosphoryl diester phosphodiesterase family protein SAK_1307 95 COG4781 COG4781, Membrane domain of membrane-anchored glycerophosphoryl diester phosphodiesterase Energy production and conversion 76786849 Common - sugar-binding transcriptional regulator, LacI family SAK_1828 122 COG1609 PurR, Transcriptional regulators Transcription 76787297 Common - universal stress family protein SAK_1689 118 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 76786821 Common - ATP-dependent RNA helicase, DEAD/DEAH box family SAK_0902 240 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 76787795 Common - aspartate aminotransferase SAK_0676 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 76787012 Common - isochorismatase family protein SAK_1686 111 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 76786874 Common gdhA glutamate dehydrogenase SAK_1366 168 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 76788680 Common vncR DNA-binding response regulator VncR SAK_0701 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 76786851 Common - iron chelate uptake ABC transporter, permease protein SAK_1105 190 COG4606 CeuB, ABC-type enterochelin transport system, permease component Inorganic ion transport and metabolism 76788073 Common - hypothetical protein SAK_1147 105 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 76786940 Common - drug:H+ antiporter-2 (DHA2) family protein SAK_1173 196 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 76788021 Common - hypothetical protein SAK_1527 189 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 76788676 Common - phosphoesterase family protein SAK_1613 30 COG0622 COG0622, Predicted phosphoesterase General function prediction only 76787669 Common pflA pyruvate formate-lyase-activating enzyme SAK_1431 80 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 76788345 Common - acetyl-CoA acetyltransferase family protein SAK_0568 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 76788689 Pathogen - hypothetical protein SAK_2038 1 None None None 76786949 Common - hypothetical protein SAK_0344 11 COG3326 COG3326, Predicted membrane protein Function unknown 76788429 Common proC pyrroline-5-carboxylate reductase SAK_0239 214 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 76787759 Common livF hydrophobic amino acid uptake (HAAT) family ABC transporter, ATP-binding protein LivF SAK_1594 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 76788288 Common - oxidoreductase, FAD/FMN-binding SAK_1150 177 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 76788558 Common bglF PTS system, beta-glucoside-specific IIABC component SAK_0915 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 76788530 Common - hypothetical protein SAK_2075 2 None None None 76787369 Common - glutamine amidotransferase domain protein SAK_1006 55 COG3442 COG3442, Predicted glutamine amidotransferase General function prediction only 76787399 Common - hypothetical protein SAK_0521 36 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 76788300 Common - conserved hypothetical integral membrane protein TIGR02206 SAK_0895 3 COG5522 COG5522, Predicted integral membrane protein Function unknown 76787911 Pathogen - hypothetical protein SAK_1213 1 None None None 76788546 Common arsC arsenate reductase SAK_1268 99 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 76788420 Common - laminin-binding surface protein SAK_1898 172 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 76788293 Common - penicillin-binding protein 2b SAK_0890 183 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 76787878 Common fhuD ferrichrome ABC transporter, ferrichrome-binding protein SAK_1426 35 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 76787022 Common - polysaccharide biosynthesis protein CpsG SAK_1256 16 COG5017 COG5017, Uncharacterized conserved protein Function unknown 76787571 Common argH argininosuccinate lyase SAK_0177 237 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 76786781 Common - PTS system, IIA component, lactose/cellobiose family SAK_0398 32 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 76786910 Common - lipase/acylhydrolase, GDSL family SAK_1189 21 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 76787875 Common - hypothetical protein SAK_1028 5 None None None 76788703 Common ptsH phosphocarrier protein HPr SAK_0945 92 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 76788233 Common atpF F0F1 ATP synthase subunit B SAK_0982 139 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 76787045 Common - PTS system, IIB component, lactose/cellobiose family SAK_1834 27 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 76787468 Common - hypothetical protein SAK_0714 4 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 76787308 Pathogen - hypothetical protein SAK_0866 1 None None None 76787780 Common fbpA fibronectin/fibrinogen binding protein SAK_1277 88 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 76787685 Common - GTPase EngB SAK_1342 198 COG0218 COG0218, Predicted GTPase General function prediction only 76787192 Common - aminoglycoside 6-adenylyltransferase, putative SAK_1967 10 None None None 76787904 Pathogen - hypothetical protein SAK_0724 1 None None None 76787574 Pathogen - hypothetical protein SAK_1958 1 None None None 76787807 Pathogen - hypothetical protein SAK_0236 1 None None None 76788360 Common - malate dehydrogenase (decarboxylating) SAK_1878 201 COG0281 SfcA, Malic enzyme Energy production and conversion 76788510 Common dltr DNA-binding response regulator DltR SAK_1814 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 76786725 Common - bacterial luciferase family protein SAK_0857 98 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 76787630 Common - lipoprotein, NPLA family SAK_1066 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 76788024 Common - carbohydrate uptake 2 (CUT2) family, carbohydrate-binding protein SAK_1050 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 76786742 Common - B3/4 domain protein SAK_2120 41 COG3382 COG3382, Uncharacterized conserved protein Function unknown 76787146 Common - ABC transporter, ATP-binding protein SAK_2129 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 76787299 Common pstC phosphate ABC transporter, permease protein PstC SAK_1926 229 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 76788093 Common proV glycine betaine/proline ABC transporter, ATP-binding protein SAK_1818 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 76787318 Common potC spermidine/putrescine ABC transporter, permease protein PotC SAK_1194 196 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 76787524 Common - O-sialoglycoprotein endopeptidase SAK_1779 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 76787330 Common - DHH family protein SAK_0687 82 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 76787799 Common - putative lipid kinase SAK_0974 109 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 76786955 Common tyrS tyrosyl-tRNA synthetase SAK_0221 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 76787935 Common - prophage LambdaSa04, major tail protein, phi13 family SAK_0753 5 None None None 76787021 Common - hypothetical protein SAK_2071 169 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 76787028 Common bag IgA-binding beta antigen SAK_0186 139 COG5373 COG5373, Predicted membrane protein Function unknown 76787071 Common - aspartate kinase SAK_0414 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 76787050 Pathogen - hypothetical protein SAK_1712 1 None None None 161486746 Common gyrB DNA gyrase subunit B SAK_0708 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 76788432 Common bioB biotin synthetase SAK_0566 177 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 76786779 Common atpD F0F1 ATP synthase subunit beta SAK_0986 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 76788569 Pathogen - hypothetical protein SAK_0803 1 None None None 76787949 Common - conserved hypothetical protein TIGR00159 SAK_1008 67 COG1624 COG1624, Uncharacterized conserved protein Function unknown 76786842 Common - hypothetical protein SAK_2057 2 None None None 76788271 Common tdk thymidine kinase SAK_1164 103 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 76786816 Common - prophage LambdaSa04, DNA primase, P4 family SAK_0730 46 COG3378 COG3378, Predicted ATPase General function prediction only 76787287 Common pyrE orotate phosphoribosyltransferase SAK_1136 191 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 76788552 Common - transcriptional regulator, LysR family SAK_1548 178 COG0583 LysR, Transcriptional regulator Transcription 76786749 Common livH hydrophobic amino acid uptake (HAAT) family ABC transporter, permease protein LivH SAK_1597 148 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 76787552 Common panE 2-dehydropantoate 2-reductase SAK_1382 129 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 76787292 Common - ABC transporter, ATP-binding protein SAK_1139 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 76787040 Common - site-specific recombinase, phage integrase family SAK_0278 149 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 76788384 Common - sortase family protein SAK_0778 22 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 76788149 Common - hypothetical protein SAK_1953 4 None None None 76788105 Common rpsU 30S ribosomal protein S21 SAK_1464 95 None None None 76786827 Common - transketolase, C-terminal subunit, putative SAK_0263 216 COG3958 COG3958, Transketolase, C-terminal subunit Carbohydrate transport and metabolism 76787508 Common - glycosyl transferase, group 2 family protein SAK_1457 133 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 76788444 Common - hypothetical protein SAK_1637 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 76788321 Common cpsD tyrosine-protein kinase CpsD SAK_1259 140 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 76788410 Common fabK enoyl-(acyl-carrier-protein) reductase II SAK_0420 142 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 76787706 Common - chaperone protein HslO, putative SAK_0774 41 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 76786987 Common - sulfatase family protein SAK_1414 51 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 76787290 Common - mannosyl-glycoprotein endo-beta-N-acetylglucosamidase, putative SAK_1870 63 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 76787158 Common - acetyltransferase, GNAT family, FRAMESHIFT SAK_1768 44 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 76787554 Common nrdI ribonucleotide reductase stimulatory protein SAK_0500 39 COG1780 NrdI, Protein involved in ribonucleotide reduction Nucleotide transport and metabolism 76788538 Common adcB zinc ABC transporter, permease protein SAK_0219 192 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 76788138 Common pepS aminopeptidase PepS SAK_1502 56 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 76787111 Common - conserved hypothetical protein TIGR00275 SAK_1775 142 COG2081 COG2081, Predicted flavoproteins General function prediction only 76787404 Common - hypothetical protein SAK_0655 1 None None None 76788062 Common murF UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase SAK_0893 211 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 76788506 Common neuD neuD protein SAK_1248 70 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 76787989 Common - hypothetical protein SAK_1303 16 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 76788080 Common rpsJ 30S ribosomal protein S10 SAK_0090 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 76786769 Common - ABC transporter, ATP-binding protein SAK_1647 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 76788032 Common - hypothetical protein SAK_0495 31 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 76787442 Common - amino acid ABC transporter, ATP-binding protein, putative SAK_0193 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 76787965 Common - ComE operon protein 1, putative SAK_0906 100 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 76788626 Common coaC phosphopantothenoylcysteine decarboxylase SAK_1153 235 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 76787585 Common - thioesterase family protein SAK_1229 27 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 76788120 Common - hypothetical protein SAK_0569 12 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 76787474 Common recR recombination protein RecR SAK_0891 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 76788352 Pathogen - hypothetical protein SAK_0295 1 None None None 76787149 Common - hypothetical protein SAK_1402 14 COG2868 COG2868, Predicted ribosomal protein Translation, ribosomal structure and biogenesis 76787257 Common - IS1381 transposase protein B SAK_0541 5 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 76786860 Common - hypothetical protein SAK_0242 1 None None None 76787850 Common greA transcription elongation factor GreA SAK_1627 201 COG0782 GreA, Transcription elongation factor Transcription 76786838 Pathogen - hypothetical protein SAK_0325 1 None None None 76787715 Common - amino acid carrier protein SAK_1231 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 76786807 Common dexB glucan 1,6-alpha-glucosidase SAK_1883 161 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 76788580 Common - amino acid ABC transporter, permease protein, putative SAK_0900 115 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 76786801 Common - transcriptional regulator, TetR family SAK_0721 16 COG1309 AcrR, Transcriptional regulator Transcription 76787099 Common livG hydrophobic amino acid uptake (HAAT) family ABC transporter, ATP-binding protein LivG SAK_1595 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 76787189 Common ssb2 single-strand DNA-binding protein SAK_0246 195 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 76787087 Common tdk thymidylate kinase SAK_1591 231 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 76788194 Common - PTS system, IIB component, mannose/fructose/sorbose family SAK_1910 40 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 76787384 Common - RNA pseudouridine synthase family protein SAK_1505 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 76788185 Common - cytidine/deoxycytidylate deaminase family protein SAK_1713 103 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 76787533 Common - formate acetyltransferase 2 SAK_0401 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 76788159 Common dltC D-alanine--poly(phosphoribitol) ligase subunit 2 SAK_1810 10 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 76787057 Common - metallo-beta-lactamase family protein SAK_1273 162 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 76788662 Common - response regulator SAK_2067 100 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 76787912 Common rplD 50S ribosomal protein L4 SAK_0092 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 76786867 Common nusG transcription antitermination protein NusG SAK_1998 215 COG0250 NusG, Transcription antiterminator Transcription 76787611 Common - hypothetical protein SAK_0152 14 COG4720 COG4720, Predicted membrane protein Function unknown 76788147 Common - acetyltransferase, GNAT family SAK_2122 64 COG2153 ElaA, Predicted acyltransferase General function prediction only 76788242 Common argG argininosuccinate synthase SAK_0176 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 76787545 Common mvaD diphosphomevalonate decarboxylase SAK_1356 29 COG3407 MVD1, Mevalonate pyrophosphate decarboxylase Lipid metabolism 76788170 Common mraW S-adenosyl-methyltransferase MraW SAK_0357 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 76786961 Common purR purine operon repressor SAK_1794 98 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 76787148 Common scpB segregation and condensation protein B SAK_1609 149 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 76786891 Common - ABC transporter, permease protein SAK_2016 50 COG4120 COG4120, ABC-type uncharacterized transport system, permease component General function prediction only 76787213 Common - hypothetical protein SAK_0870 5 None None None 76788588 Common - glutathione S-transferase domain protein SAK_0925 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 76788652 Common - prophage LambdaSa03, site-specific recombinase, phage integrase family SAK_0607 86 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 76788220 Common rplN 50S ribosomal protein L14 SAK_0101 247 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 76787282 Common ftsA cell division protein FtsA SAK_0580 177 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 76786907 Common - hypothetical protein SAK_0012 11 COG2367 PenP, Beta-lactamase class A Defense mechanisms 76788063 Common - transcriptional regulator, PadR family SAK_0336 60 COG1695 COG1695, Predicted transcriptional regulators Transcription 76787924 Common - sensory box histidine kinase SAK_0846 223 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 76787650 Common asd aspartate-semialdehyde dehydrogenase SAK_1141 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 76787233 Pathogen - hypothetical protein SAK_1960 1 None None None 76786800 Common - oxidoreductase, aldo/keto reductase family SAK_1693 193 COG4989 COG4989, Predicted oxidoreductase General function prediction only 76787699 Common - acetyltransferase, GNAT family SAK_0062 4 COG3393 COG3393, Predicted acetyltransferase General function prediction only 76787845 Common - CRISPR-associated protein Cas2, putative SAK_1019 21 COG3512 COG3512, Uncharacterized protein conserved in bacteria Function unknown 76788201 Common galT galactose-1-phosphate uridylyltransferase SAK_0537 14 COG4468 GalT, Galactose-1-phosphate uridyltransferase Carbohydrate transport and metabolism 76787121 Common - IS861, transposase orfA SAK_1549 5 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 76787491 Common rplE 50S ribosomal protein L5 SAK_0103 247 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 76787884 Common - acyltransferase, putative SAK_0085 103 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 76788127 Common - metallo-beta-lactamase family protein SAK_0473 64 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 76788525 Common - fibrinogen-binding protein, putative SAK_1142 32 None None None 76788212 Common rpmF 50S ribosomal protein L32 SAK_2048 55 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 76787030 Pathogen - hypothetical protein SAK_0297 1 None None None 76787328 Common - oxidoreductase, short chain dehydrogenase/reductase family SAK_1176 235 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 76787250 Pathogen cfb CAMP factor SAK_1983 2 None None None 76788621 Common metI D-methionine ABC transporter, permease protein SAK_1652 100 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 76787103 Common - putative L-xylulose 5-phosphate 3-epimerase SAK_1831 28 COG3623 SgaU, Putative L-xylulose-5-phosphate 3-epimerase Carbohydrate transport and metabolism 76788411 Common - PTS system, IIAB component, mannose/fructose/sorbose family SAK_0435 42 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 76787362 Common - PTS system, IIBC component SAK_0354 43 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 76788378 Common - prophage Sa05, BRO domain protein SAK_2090 19 COG3617 COG3617, Prophage antirepressor Transcription 76787090 Common - cysteine desulfurase, putative SAK_1183 238 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 76788103 Common - 4-oxalocrotonate tautomerase SAK_1165 13 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 76788614 Common - N-acetylmannosamine-6-phosphate 2-epimerase SAK_0066 43 COG3010 NanE, Putative N-acetylmannosamine-6-phosphate epimerase Carbohydrate transport and metabolism 76788045 Common rpmB 50S ribosomal protein L28 SAK_0180 88 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 76787008 Common - IS861, transposase orfA SAK_0504 5 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 76788254 Pathogen - hypothetical protein SAK_1122 1 None None None 76787321 Common - PTS system, IIA component, putative SAK_1895 13 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 76787011 Common - ApbE family protein SAK_1166 127 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 76787956 Common - hypothetical protein SAK_1776 8 COG1085 GalT, Galactose-1-phosphate uridylyltransferase Energy production and conversion 76788089 Common rplK 50S ribosomal protein L11 SAK_1544 247 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 76787273 Common - peptidase propeptide and YPEB domain protein SAK_2060 4 COG3212 COG3212, Predicted membrane protein Function unknown 76786981 Common hslO Hsp33-like chaperonin SAK_1844 137 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 76787903 Common dltA D-alanine--D-alanyl carrier protein ligase SAK_1812 219 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 76788701 Common - prophage Sa05, membrane protein, putative SAK_2073 47 COG1511 COG1511, Predicted membrane protein Function unknown 76787605 Common glyA serine hydroxymethyltransferase SAK_1160 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 76787865 Common - hypothetical protein SAK_0432 10 COG4687 COG4687, Uncharacterized protein conserved in bacteria Function unknown 76788168 Common - acetyltransferase, GNAT family SAK_1973 18 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 76787749 Common thiI thiamine biosynthesis protein ThiI SAK_1405 94 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 76787672 Common - peptide/opine/nickel uptake (PepT) family ABC transporter, permease protein SAK_0254 221 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 76788266 Common fba fructose-bisphosphate aldolase SAK_0178 179 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 76787210 Common - carbonic anhydrase, putative SAK_0162 62 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 76788295 Common - FMN-binding protein SAK_1736 8 None None None 76788496 Common upp uracil phosphoribosyltransferase SAK_1601 165 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 76788501 Common - iron chelate uptake ABC transporter, permease protein SAK_1104 162 COG4605 CeuC, ABC-type enterochelin transport system, permease component Inorganic ion transport and metabolism 76787955 Pathogen - hypothetical protein SAK_2086 1 None None None 76788253 Common argF ornithine carbamoyltransferase SAK_2123 234 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 76787466 Common - glycosyl transferase, group 2 family protein SAK_1446 16 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 76788285 Common pcsB PcsB protein SAK_0050 17 COG3883 COG3883, Uncharacterized protein conserved in bacteria Function unknown 76788172 Common potA spermidine/putrescine ABC transporter, ATP-binding protein SAK_1196 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 76787656 Common - hypothetical protein SAK_0917 35 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 76787221 Common rbsB ribose ABC transporter, ribose-binding protein SAK_0166 119 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 76787647 Common - PTS system, galactitol-specific IIC component, putative SAK_0526 19 COG3775 GatC, Phosphotransferase system, galactitol-specific IIC component Carbohydrate transport and metabolism 76787519 Common - BioY family protein SAK_0565 90 COG1268 BioY, Uncharacterized conserved protein General function prediction only 76788451 Common - arginine repressor, putative SAK_0601 55 COG1438 ArgR, Arginine repressor Transcription 76787760 Common - hypothetical protein SAK_1032 3 None None None 76786929 Common recJ single-stranded-DNA-specific exonuclease RecJ SAK_1294 196 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 76786975 Common sufC FeS assembly ATPase SufC SAK_0199 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 76787390 Common - transcriptional regulator, GntR family SAK_1063 137 COG2188 PhnF, Transcriptional regulators Transcription 76787018 Common - polar amino acid uptake (PAAT) family ABC transporter, ATP-binding protein SAK_1043 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 76788338 Common - quaternary amine uptake (QAT) family ABC transporter, amino acid-binding protein SAK_0301 85 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 76788426 Pathogen - hypothetical protein SAK_0287 1 None None None 76786883 Common - hydrolase, NUDIX family SAK_1560 94 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 76786753 Common copA copper-translocating P-type ATPase SAK_0459 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 76786988 Common dtd D-tyrosyl-tRNA deacylase SAK_1899 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 76787067 Common - transcriptional regulator, DeoR family SAK_1379 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 76788002 Common - competence protein CoiA, putative SAK_0928 13 COG4469 CoiA, Competence protein General function prediction only 76788593 Common - phage infection protein, putative SAK_1127 22 COG1511 COG1511, Predicted membrane protein Function unknown 76787618 Common clpE ATP-dependent Clp protease, ATP-binding subunit ClpE SAK_0590 216 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 76786738 Pathogen - hypothetical protein SAK_0651 1 None None None 76787228 Common - PTS system, IIC component, putative SAK_1893 19 COG3775 GatC, Phosphotransferase system, galactitol-specific IIC component Carbohydrate transport and metabolism 76787843 Common rpmI 50S ribosomal protein L35 SAK_1416 128 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 76787741 Common - amino acid ABC transporter, ATP-binding protein, putative SAK_1653 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 76787970 Common - hypothetical protein SAK_0904 74 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 76787424 Common - competence protein ComFC, putative SAK_0407 56 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 76788381 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase SAK_1566 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 76786872 Common - cobalt ABC transporter, putative, ATP-binding protein SAK_2109 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 76788385 Common secG preprotein translocase subunit SecG SAK_1513 2 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 76786752 Common - hypothetical protein SAK_0723 6 None None None 76787175 Pathogen - hypothetical protein SAK_1892 1 None None None 76787909 Common - HD domain protein SAK_0662 87 COG1078 COG1078, HD superfamily phosphohydrolases General function prediction only 76787113 Common galE UDP-glucose 4-epimerase SAK_0538 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 76787842 Common - hypothetical protein SAK_1971 4 None None None 76788450 Common cysE serine O-acetyltransferase SAK_0268 189 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 76787326 Common - prophage LambdaSa04, RelB antitoxin family protein SAK_0743 9 COG3077 RelB, DNA-damage-inducible protein J DNA replication, recombination, and repair 76788491 Common - hypothetical protein SAK_1706 30 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 76787003 Pathogen - hypothetical protein SAK_0615 1 None None None 76787980 Common coaB phosphopantothenate--cysteine ligase SAK_1152 164 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 76787421 Common - glycosyl transferase, group 2 family protein SAK_1450 76 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 76787395 Common - hypothetical protein SAK_1619 80 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 76787655 Common holA DNA polymerase III subunit delta SAK_0912 38 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 76788107 Common - transcriptional regulator, AraC family SAK_1191 139 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 76787748 Common galE UDP-glucose 4-epimerase SAK_1882 233 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 76787230 Common - IS1381 transposase protein A SAK_1209 5 None None None 76788272 Common - DNA-binding response regulator SAK_2061 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 76787500 Common rbsA ribose ABC transporter, ATP-binding protein SAK_0168 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 76788417 Common xth exodeoxyribonuclease III SAK_1581 195 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 76787734 Common papS tRNA CCA-pyrophosphorylase SAK_1372 214 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 76786985 Common polA DNA polymerase I SAK_0463 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 76788638 Common - hypothetical protein SAK_0678 18 None None None 76786920 Common - hypothetical protein SAK_1031 6 COG0398 COG0398, Uncharacterized conserved protein Function unknown 76788462 Common - concentrative nucleoside transporter (CNT) family protein SAK_2010 68 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 76788636 Common topA DNA topoisomerase I SAK_1100 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 76788100 Common - prophage LambdaSa04, holin SAK_0760 13 COG4824 COG4824, Phage-related holin (Lysis protein) General function prediction only 76787675 Common mscL large conductance mechanosensitive channel protein SAK_1463 143 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 76787266 Common - hypothetical protein SAK_1640 7 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 76787064 Common pfkA 6-phosphofructokinase SAK_1036 155 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 76786824 Common - hypothetical protein SAK_2055 3 None None None 76788408 Common hisS histidyl-tRNA synthetase SAK_2047 248 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 76787587 Common - hypothetical protein SAK_2072 8 COG3759 COG3759, Predicted membrane protein Function unknown 76788040 Common ftsY signal recognition particle-docking protein FtsY SAK_0853 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 76787276 Common - hypothetical protein SAK_2134 166 COG1576 COG1576, Uncharacterized conserved protein Function unknown 76788518 Common nikC nickel ABC transporter, permease protein SAK_1540 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 76788591 Common pepO endopeptidase O SAK_1859 63 COG3590 PepO, Predicted metalloendopeptidase Posttranslational modification, protein turnover, chaperones 76788512 Common - transcriptional regulator, MerR family SAK_1932 61 COG0789 SoxR, Predicted transcriptional regulators Transcription 76787614 Common mutL DNA mismatch repair protein SAK_2037 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 76787268 Common - RNA methyltransferase, TrmH family SAK_0272 216 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 76788374 Common grpE co-chaperone protein GrpE SAK_0146 195 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 76788362 Common - CBS domain protein SAK_1432 218 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 76788570 Common - capsular polysaccharide biosynthesis protein CpsJ SAK_1253 216 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 76787494 Common atpE ATP synthase F0, C subunit SAK_0980 12 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 76788698 Common csrR DNA-binding response regulator CsrR SAK_1639 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 76788649 Common ciaH sensor histidine kinase CiaH SAK_1079 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76787597 Common - amino acid ABC transporter, amino acid-binding protein, putative SAK_1656 127 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 76788263 Common - phosphoglucomutase/phosphomannomutase family protein SAK_0594 237 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 76787191 Common recF recombination protein F SAK_2114 169 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 76787091 Common - hypothetical protein SAK_1390 21 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 76787866 Common - prophage LambdaSa04, mannosyl-glycoprotein endo-beta-N-acetylglucosamidase family protein SAK_0761 67 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 76788708 Common - allulose-6-phosphate 3-epimerase SAK_1758 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 76788176 Common - glycosyl hydrolase, family 3 SAK_0831 177 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 76786759 Common - hypothetical protein SAK_1501 1 None None None 76788186 Common - polysaccharide deacetylase family protein SAK_1206 88 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 76788627 Pathogen - hypothetical protein SAK_0614 1 None None None 76788691 Common rbsD ribose ABC transporter protein RbsD SAK_0169 44 COG1869 RbsD, ABC-type ribose transport system, auxiliary component Carbohydrate transport and metabolism 76786936 Common - hypothetical protein SAK_1530 3 None None None 76786733 Common - PTS system IIA domain protein SAK_0523 42 COG3711 BglG, Transcriptional antiterminator Transcription 76786901 Common rpmE2 50S ribosomal protein L31 type B SAK_0686 168 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 76788264 Pathogen - pathogenicity protein, putative, interuption N-terminus SAK_2002 1 None None None 76788481 Pathogen - hypothetical protein SAK_0639 1 None None None 76787224 Common - FemAB family protein SAK_0659 21 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 76787687 Pathogen - hypothetical protein SAK_1442 1 None None None 76788422 Common htrA serine peptidase HtrA SAK_2135 221 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 76786911 Common - ABC transporter, substrate-binding protein, putative SAK_1276 59 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 76788477 Common trx thioredoxin SAK_1725 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 76787122 Common atpA F0F1 ATP synthase subunit alpha SAK_0984 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 76787753 Common def peptide deformylase SAK_1365 154 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 76788337 Common oppF oligopeptide ABC transporter, ATP-binding protein SAK_0210 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 76787092 Common - PRD domain/PTS system IIA domain protein SAK_1762 47 COG3711 BglG, Transcriptional antiterminator Transcription 76788439 Common tig trigger factor SAK_0155 214 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 76787997 Common - beta-lactamase, putative SAK_0786 72 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 76787129 Common - hypothetical protein SAK_0429 1 None None None 76787367 Common cpsE glycosyl transferase CpsE SAK_1258 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 76787252 Common - biotin--protein ligase SAK_0953 174 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 76787918 Common - cell division protein, FtsW/RodA/SpoVE family SAK_0706 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 76788543 Common - hypothetical protein SAK_1715 7 None None None 76787863 Pathogen - prophage LambdaSa03, holin, phi LC3 family SAK_0652 1 COG5546 COG5546, Small integral membrane protein Function unknown 76787211 Common - major facilitator family transporter SAK_2036 62 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 76786839 Common - hypothetical protein SAK_0788 29 COG4587 COG4587, ABC-type uncharacterized transport system, permease component General function prediction only 76788542 Common rpe ribulose-phosphate 3-epimerase SAK_1798 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 76788585 Common - 67 kDa myosin-cross-reactive streptococcal antigen SAK_1532 25 COG4716 COG4716, Myosin-crossreactive antigen Function unknown 76787470 Pathogen - hypothetical protein SAK_1806 1 COG4849 COG4849, Uncharacterized protein conserved in bacteria Function unknown 76787661 Common - hydroxymethylglutaryl-CoA reductase, degradative SAK_1348 55 COG1257 HMG1, Hydroxymethylglutaryl-CoA reductase Lipid metabolism 76788085 Common purC phosphoribosylaminoimidazole-succinocarboxamide synthase SAK_0057 214 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 76788071 Common - hypothetical protein SAK_1281 210 COG0628 PerM, Predicted permease General function prediction only 76787168 Common - kinase, PfkB family SAK_0823 90 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 76787363 Common - rhodanese-like domain protein SAK_0574 28 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 76787985 Common ndk nucleoside diphosphate kinase SAK_1021 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 76788200 Common folD methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase SAK_0595 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 76787931 Common gapN glyceraldehyde-3-phosphate dehydrogenase, NADP-dependent SAK_0947 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 76786803 Common uvrC excinuclease ABC subunit C SAK_1308 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 76786895 Common metK S-adenosylmethionine synthetase SAK_0954 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 76787714 Common - ABC transporter, substrate-binding protein SAK_0901 99 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 76788158 Common nrdI hypothetical protein SAK_1902 33 COG1780 NrdI, Protein involved in ribonucleotide reduction Nucleotide transport and metabolism 76786964 Common - PTS system, galactitol-specific IIB component, putative SAK_0530 17 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 76786890 Common - modification methylase, HemK family SAK_1162 233 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 76788028 Common rplJ 50S ribosomal protein L10 SAK_1335 216 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 76787535 Common - ABC transporter, substrate-binding protein SAK_2017 59 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 76786879 Common - carbohydrate kinase SAK_0596 216 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 76787825 Common - 5-formyltetrahydrofolate cyclo-ligase family protein SAK_0476 101 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 76787857 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase SAK_0966 213 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 76788216 Common def peptide deformylase SAK_1863 211 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 76786768 Pathogen - hypothetical protein SAK_1119 1 None None None 76787921 Pathogen - hypothetical protein SAK_1994 1 None None None 76787543 Common - conserved hypothetical protein/bacteriophage resistance protein SAK_0619 2 None None None 76788030 Common - permease, GntP family SAK_0919 24 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 76787218 Common - surface protein Spb1 SAK_1440 10 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 76787059 Common nadD nicotinic acid mononucleotide adenyltransferase SAK_1674 185 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 76788560 Common - hypothetical protein SAK_0728 15 None None None 76787411 Common trpS tryptophanyl-tRNA synthetase II SAK_2126 247 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 76788252 Common - metal ion transporter, CorA family SAK_0550 9 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 76787541 Common - hypothetical protein SAK_0745 2 None None None 76787444 Common pbpX penicillin-binding protein 2X SAK_0359 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 76787957 Pathogen - hypothetical protein SAK_0767 1 None None None 76787446 Pathogen - hypothetical protein SAK_0629 1 None None None 76787388 Common - glycosyl transferase family protein SAK_0198 228 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 76787762 Common - prophage LambdaSa04, HNH endonuclease family protein SAK_0737 33 COG1403 McrA, Restriction endonuclease Defense mechanisms 76786853 Common - iron chelate uptake ABC transporter, iron chelate-binding protein SAK_1102 43 COG4607 CeuA, ABC-type enterochelin transport system, periplasmic component Inorganic ion transport and metabolism 76787880 Common purK phosphoribosylaminoimidazole carboxylase ATPase subunit SAK_0078 193 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 76787033 Common - flavodoxin SAK_0689 63 COG0716 FldA, Flavodoxins Energy production and conversion 76787084 Common - acetyltransferase, GNAT family SAK_0329 98 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 76787358 Pathogen - capsular polysaccharide biosynthesis protein CpsK SAK_1252 3 None None None 76787823 Common - sialidase domain protein SAK_1891 17 COG4409 NanH, Neuraminidase (sialidase) Carbohydrate transport and metabolism 76788140 Common uvrA excinuclease ABC subunit A SAK_1717 240 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 76787794 Pathogen cylK CylK protein SAK_0801 1 None None None 76787606 Common - CsbD family protein SAK_1222 26 None None None 76786817 Common - hypothetical protein SAK_1146 13 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 76787946 Common - hypothetical protein SAK_1952 2 None None None 76787137 Common - potassium uptake protein, K+ transporter (Trk) family SAK_1645 148 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 76787023 Common - conserved hypothetical protein TIGR02327 SAK_0988 1 None None None 76787697 Common ispD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase SAK_1452 190 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 76788405 Common - cell division protein FtsX, putative SAK_0670 71 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 76788017 Common - hypothetical protein SAK_2063 40 COG1288 COG1288, Predicted membrane protein Function unknown 76788142 Common - 1-phosphofructokinase, putative SAK_1378 100 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 76788574 Common - purine transporter, AzgA family SAK_0439 135 COG2252 COG2252, Permeases General function prediction only 76787201 Common rplA 50S ribosomal protein L1 SAK_1543 239 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 76788545 Common ppaC putative manganese-dependent inorganic pyrophosphatase SAK_1430 54 COG1227 PPX1, Inorganic pyrophosphatase/exopolyphosphatase Energy production and conversion 76788119 Common pgk phosphoglycerate kinase SAK_1788 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 76787982 Common cylG cylG protein SAK_0792 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 76788259 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein SAK_1062 239 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 76786785 Common - cell division protein, FtsW/RodA/SpoVE family SAK_0886 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 76787978 Common gyrA DNA gyrase subunit A SAK_1055 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 76787296 Common rpmA 50S ribosomal protein L27 SAK_1401 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 76787406 Common - DNA processing protein DprA, putative SAK_1101 211 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 76787151 Common prfC peptide chain release factor 3 SAK_0897 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 76788097 Common - hypothetical protein SAK_0245 7 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 76787150 Common - prophage Sa05, DNA replication protein, putative SAK_2084 6 None None None 76788065 Common - DegV family protein SAK_0274 55 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 76788250 Common - prophage LambdaSa03, pblA protein, internal deletion SAK_0645 16 COG5412 COG5412, Phage-related protein Function unknown 76787169 Common - glycerate kinase SAK_0918 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 76788225 Common cpsL polysaccharide biosynthesis protein CpsL SAK_1251 48 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 76786856 Common - ABC transporter, ATP-binding protein SAK_0699 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 76788564 Common frr ribosome recycling factor SAK_1536 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 76787520 Common lmb laminin-binding surface protein SAK_1319 169 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 76787430 Common - hypothetical protein SAK_1009 13 COG4856 COG4856, Uncharacterized protein conserved in bacteria Function unknown 76787599 Common - hypothetical protein SAK_1816 20 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 76787455 Common - cation-transporting ATPase, P-type, HAD superfamily, subfamily IC SAK_1027 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 76787592 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase SAK_1299 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 76788554 Common - hypothetical protein SAK_0010 10 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 76786810 Common - hypothetical protein SAK_1936 4 None None None 161486747 Common rpsT 30S ribosomal protein S20 SAK_1045 37 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 76786882 Common - glycosyl hydrolase, family 1 SAK_0916 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 76787197 Pathogen - hypothetical protein SAK_2078 1 None None None 76787806 Common - transcriptional regulator, MarR family SAK_1363 16 COG1846 MarR, Transcriptional regulators Transcription 76787529 Common - DNA-entry nuclease, putative SAK_0814 5 COG1864 NUC1, DNA/RNA endonuclease G, NUC1 Nucleotide transport and metabolism 76787852 Common - Cof-like hydrolase family protein SAK_1190 122 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 76788500 Common - polar amino acid uptake (PAAT) family ABC transporter, polar amino acid-binding protein SAK_1625 94 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 76786775 Common - inositol monophosphatase family protein SAK_1089 184 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 76787774 Common adcA zinc ABC transporter, zinc-binding protein AdcA SAK_0685 163 COG3443 COG3443, Predicted periplasmic or secreted protein General function prediction only 76787804 Common thrS threonyl-tRNA synthetase SAK_0837 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 76786748 Common - amino acid (AAT) family permease protein SAK_1338 159 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 76787130 Common rnz ribonuclease Z SAK_1296 116 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 76787645 Common xseA exodeoxyribonuclease VII large subunit SAK_0597 204 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 76788678 Common dnaC replicative DNA helicase SAK_2097 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 76787319 Common - ABC transporter, ATP-binding protein SAK_1069 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 76788059 Common - sensor histidine kinase SAK_0391 147 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 76787537 Common truA tRNA pseudouridine synthase A SAK_0150 237 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 76788325 Common - phosphinothricin N-acetyltransferase, putative SAK_1847 101 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 76788166 Common msrA methionine sulfoxide reductase A SAK_1534 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 76787439 Common infB translation initiation factor IF-2 SAK_0455 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 76787624 Pathogen - hypothetical protein SAK_0323 1 None None None 76786877 Common - DNA-binding response regulator SAK_0845 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 76786784 Common plsX fatty acid/phospholipid synthesis protein SAK_0055 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 76787356 Common - regulatory protein CpsX SAK_1262 61 COG1316 LytR, Transcriptional regulator Transcription 76787016 Common - hypothetical protein SAK_0543 2 None None None 76786977 Common - chloride channel (ClC) family protein SAK_1192 155 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 76788371 Common rpsL 30S ribosomal protein S12 SAK_1793 236 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 76788436 Common - phosphomevalonate kinase SAK_1355 14 COG1577 ERG12, Mevalonate kinase Lipid metabolism 76787580 Pathogen - hypothetical protein SAK_0734 1 None None None 76787037 Common ygjU dicarboxylate/amino acid,cation (Na+ or H+) symporter (DAACS) family protein YgjU SAK_1649 148 COG3633 SstT, Na+/serine symporter Amino acid transport and metabolism 76787331 Common - ABC transporter, ATP-binding protein SAK_2015 249 COG1101 PhnK, ABC-type uncharacterized transport system, ATPase component General function prediction only 76788058 Common - ABC transporter, substrate-binding protein SAK_1074 181 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 76787705 Common - hypothetical protein SAK_0809 21 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 76786947 Pathogen - hypothetical protein SAK_0613 1 None None None 76787115 Common lacC tagatose-6-phosphate kinase SAK_1888 100 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 76788132 Common folE GTP cyclohydrolase I SAK_1201 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 76786811 Common - hypothetical protein SAK_1956 8 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 76787029 Common - GIY-YIG domain protein SAK_0903 81 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 76787242 Pathogen - hypothetical protein SAK_1954 1 None None None 76787205 Common proA gamma-glutamyl phosphate reductase SAK_0356 193 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 76787371 Common rplR 50S ribosomal protein L18 SAK_0107 216 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 76787514 Common - ABC transporter, permease protein SAK_1275 89 COG4120 COG4120, ABC-type uncharacterized transport system, permease component General function prediction only 76788249 Common fmt methionyl-tRNA formyltransferase SAK_0386 219 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 76788151 Common - cold shock protein SAK_2039 182 COG1278 CspC, Cold shock proteins Transcription 76788348 Common - hypothetical protein SAK_2044 79 COG1284 COG1284, Uncharacterized conserved protein Function unknown 76788681 Common atpB F0F1 ATP synthase subunit A SAK_0981 200 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 76787301 Common - hypothetical protein SAK_1413 129 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 76788235 Pathogen - hypothetical protein SAK_1300 1 None None None 76787190 Common - GAF domain protein SAK_0951 78 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 76788706 Common infC translation initiation factor IF-3 SAK_1417 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 76787739 Common - hypothetical protein SAK_0865 3 None None None 76787512 Common - carbohydrate uptake 1 (CUT1) family ABC transporter, carbohydrate-binding protein SAK_0067 61 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 76788669 Common typA GTP-binding protein TypA SAK_0575 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 76787177 Pathogen - hypothetical protein SAK_0765 2 None None None 76788442 Common - hypothetical protein SAK_0231 2 COG4940 ComGF, Competence protein ComGF Intracellular trafficking and secretion 76787480 Pathogen - hypothetical protein SAK_0625 1 None None None 76787784 Common deoD purine nucleoside phosphorylase SAK_1265 98 COG0813 DeoD, Purine-nucleoside phosphorylase Nucleotide transport and metabolism 76787046 Common - hypothetical protein SAK_0070 20 COG2731 EbgC, Beta-galactosidase, beta subunit Carbohydrate transport and metabolism 76786934 Common - prophage LambdaSa03, structural protein, putative SAK_0642 4 None None None 76787481 Common - hypothetical protein SAK_0719 23 COG4283 COG4283, Uncharacterized conserved protein Function unknown 76788443 Common - peptidase, A24A (type 4 prepilin peptidase 1) subfamily SAK_0571 4 None None None 76786870 Common ldh L-lactate dehydrogenase SAK_1054 164 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 76787145 Common rpsB 30S ribosomal protein S2 SAK_1852 221 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 76788031 Common - hypothetical protein SAK_1664 31 COG3412 COG3412, Uncharacterized protein conserved in bacteria Function unknown 76787077 Common - decarboxylase family protein SAK_1980 118 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 76788505 Common - hypothetical protein SAK_0461 131 COG2860 COG2860, Predicted membrane protein Function unknown 76788112 Common oppD oligopeptide ABC transporter, permease protein SAK_0207 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 76787385 Common - hypothetical protein SAK_1578 14 COG3619 COG3619, Predicted membrane protein Function unknown 76787967 Common asnA asparagine synthetase AsnA SAK_0552 31 COG2502 AsnA, Asparagine synthetase A Amino acid transport and metabolism 76788003 Common - lactose operon protein LacX SAK_1886 41 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 76787838 Common cfa cyclopropane-fatty-acyl-phospholipid synthase SAK_1771 138 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 76788535 Common - tRNA-dihydrouridine synthase family protein SAK_1845 211 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 76787729 Common - hypothetical protein SAK_0335 5 None None None 76787755 Common - lipase/acylhydrolase, GDSL family SAK_0604 20 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 76788357 Common malQ 4-alpha-glucanotransferase SAK_1473 112 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 76788603 Common manA mannose-6-phosphate isomerase, class I SAK_1700 50 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 76786798 Common - acylphosphatase SAK_1622 29 COG1254 AcyP, Acylphosphatases Energy production and conversion 76787613 Common - aminotransferase, classes I and II SAK_1602 230 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 76787061 Common rpsO 30S ribosomal protein S15 SAK_0265 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 76786735 Common - NADPH-dependent FMN reductase domain protein SAK_1168 106 COG2461 COG2461, Uncharacterized conserved protein Function unknown 76787062 Common - hypothetical protein SAK_1487 9 None None None 76787516 Common - hypothetical protein SAK_0848 5 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 76788460 Common rhaD rhamnulose-1-phosphate aldolase SAK_0527 29 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 76786717 Common - ribosomal large subunit pseudouridine synthase, RluA family SAK_2006 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 76788197 Common - oxidoreductase, aldo/keto reductase family SAK_0513 163 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 76787677 Common rplV 50S ribosomal protein L22 SAK_0096 234 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 76787616 Common - ABC transporter, ATP-binding protein SAK_1033 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 76787334 Common - PTS system, galactitol-specific IIA component, putative SAK_0528 23 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 76788376 Common scrB sucrose-6-phosphate hydrolase SAK_1703 52 COG1621 SacC, Beta-fructosidases (levanase/invertase) Carbohydrate transport and metabolism 76788589 Common pheS phenylalanyl-tRNA synthetase subunit alpha SAK_0992 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 76788599 Pathogen - hypothetical protein SAK_0818 1 None None None 76787216 Common - IS1381 transposase protein A SAK_0191 5 None None None 76787854 Common aroE shikimate 5-dehydrogenase SAK_1692 221 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 76786992 Common codY transcriptional repressor CodY SAK_1687 20 COG4465 CodY, Pleiotropic transcriptional repressor Transcription 76786903 Common - transcriptional regulator, GntR family/TrkA domain protein SAK_1220 18 COG0490 COG0490, Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels Inorganic ion transport and metabolism 76788261 Common - polysaccharide biosynthesis protein SAK_1423 44 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 76786916 Pathogen - hypothetical protein SAK_0011 1 None None None 76788156 Pathogen - hypothetical protein SAK_0643 1 None None None 76787226 Common - glutamine amidotransferase class I domain protein SAK_1657 122 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 76788042 Pathogen - hypothetical protein SAK_0546 1 None None None 76788336 Common - GDXG lipolytic enzyme family protein SAK_0910 53 COG0657 Aes, Esterase/lipase Lipid metabolism 76787600 Common - acyl carrier protein SAK_0793 44 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 76787497 Common adk adenylate kinase SAK_0112 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 76788068 Common - serine/threonine protein kinase, putative SAK_0766 119 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 76787509 Common - pyridoxamine 5'-phosphate oxidase family SAK_0503 19 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 76787496 Common - transcriptional regulator, putative SAK_1743 8 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 76788697 Common mvk mevalonate kinase SAK_1357 34 COG1577 ERG12, Mevalonate kinase Lipid metabolism 76787448 Common murC UDP-N-acetylmuramate--L-alanine ligase SAK_1630 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 76787732 Common - inosine-uridine preferring nucleoside hydrolase family protein SAK_0679 89 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 76786922 Common - glycine betaine/carnitine/choline ABC transporter, ATP-binding protein SAK_2068 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 76787393 Common lacD tagatose 1,6-diphosphate aldolase SAK_1887 25 COG3684 LacD, Tagatose-1,6-bisphosphate aldolase Carbohydrate transport and metabolism 76786750 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 family protein SAK_0247 190 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 76788049 Common - transcriptional regulator, SorC family SAK_0397 67 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 76788602 Common - cell division protein DivIVA, putative SAK_0586 43 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 76787620 Common - hypothetical protein SAK_0608 9 COG2314 XynA, Predicted membrane protein Function unknown 76788562 Common xseB exodeoxyribonuclease VII small subunit SAK_0598 77 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 76787005 Common - DJ-1/PfpI family protein SAK_1950 26 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 76787381 Common - prophage Sa05, transcriptional regulator, putative SAK_2074 19 COG1309 AcrR, Transcriptional regulator Transcription 76787999 Common - hypothetical protein SAK_1271 3 COG5549 COG5549, Predicted Zn-dependent protease Posttranslational modification, protein turnover, chaperones 76788134 Common rplT 50S ribosomal protein L20 SAK_1415 213 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 76788396 Common - PTS system, fructose-specific, IIA component SAK_1760 107 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 76788238 Common - isoprenylcysteine carboxyl methyltransferase (ICMT) family protein SAK_0339 17 COG1755 COG1755, Uncharacterized protein conserved in bacteria Function unknown 76787974 Common nrdG anaerobic ribonucleoside-triphosphate reductase activating protein SAK_2021 62 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 76786832 Common - isochorismatase family protein SAK_1672 45 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 76787702 Common - hypothetical protein SAK_1567 5 None None None 76787595 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase SAK_1424 210 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 76787235 Common acpP acyl carrier protein SAK_0419 179 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 76787278 Common rnhB ribonuclease HII SAK_1107 209 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 76787609 Common ulaA ascorbate-specific PTS system enzyme IIC SAK_0261 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 76788577 Common sufB FeS assembly protein SufB SAK_0203 187 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 76787239 Common - PTS system, IID component, mannose/fructose/sorbose family SAK_1908 40 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 76787502 Common gloA lactoylglutathione lyase SAK_1508 129 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 76788415 Common - hypothetical protein SAK_1770 102 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 76787746 Common uvrB excinuclease ABC subunit B SAK_1495 228 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 76788122 Common udk uridine kinase SAK_0950 80 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 76788540 Common - hydrolase, NUDIX family SAK_1529 37 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 76788179 Common phoU phosphate transport system regulatory protein PhoU SAK_1082 199 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 76787244 Common ssb1 single-strand DNA-binding protein SAK_1721 214 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 76786982 Common - hypothetical protein SAK_2043 2 None None None 76788070 Common - CAAX amino terminal protease family protein SAK_0238 24 None None None 76787712 Common - hypothetical protein SAK_1460 150 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 76787569 Common pepQ Xaa-Pro dipeptidase SAK_0832 248 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 76787548 Common - transcriptional regulator, LysR family SAK_0819 190 COG0583 LysR, Transcriptional regulator Transcription 76788634 Common - site-specific recombinase, phage integrase family SAK_2059 86 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 76787345 Common - hypothetical protein SAK_2096 12 COG4466 Veg, Uncharacterized protein conserved in bacteria Function unknown 76788549 Common - cation diffusion facilitator (CDF) family protein SAK_1232 189 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 76788247 Common - FtsK/SpoIIIE family protein SAK_1123 198 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 76787074 Common - prophage LambdaSa03, helicase, putative SAK_0617 112 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 76787248 Common ftsE cell division ATP binding protein FtsE SAK_0669 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 76787348 Pathogen - hypothetical protein SAK_1470 1 None None None 76788037 Common - efflux ABC transporter, permease/ATP-binding protein SAK_1361 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 76787833 Pathogen - hypothetical protein SAK_1753 1 None None None 76787094 Common - probable proton-coupled thiamine transporter YuaJ SAK_0940 13 COG3859 COG3859, Predicted membrane protein Function unknown 76787827 Common - voltage-gated chloride channel family protein SAK_0691 114 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 76787859 Common - Mn2+/Fe2+ transporter, NRAMP family SAK_0871 90 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 76788654 Common - hypothetical protein SAK_1658 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 76786726 Pathogen - hypothetical protein SAK_0628 1 None None None 76787938 Common - hypothetical protein SAK_1912 6 None None None 76788102 Common - DedA family protein SAK_0815 152 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 76788282 Common - aromatic amino acid aminotransferase SAK_0052 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 76788622 Common - acetyltransferase, GNAT family SAK_1025 50 COG0456 RimI, Acetyltransferases General function prediction only 76787710 Common - LrgA family protein SAK_1233 58 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 76786766 Common sodA superoxide dismutase, Mn SAK_0913 207 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 76788208 Common - iojap-related protein SAK_1671 201 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 76788710 Common - nitroreductase family protein SAK_1507 77 COG0778 NfnB, Nitroreductase Energy production and conversion 76787082 Common mutY A/G-specific adenine glycosylase SAK_1723 211 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 76787792 Common - azaleucine resistance protein AzlC, putative SAK_1990 110 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 76788470 Common - conserved hypothetical protein TIGR01440 SAK_0153 16 COG4475 COG4475, Uncharacterized protein conserved in bacteria Function unknown 76787950 Common - CorA metal ion transporter (MIT) family protein SAK_1719 88 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 76787969 Common - hypothetical protein SAK_1962 2 None None None 76787582 Common - DNA-binding response regulator, AraC family SAK_1906 216 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 76786933 Common - GTP-binding protein SAK_1676 43 COG1161 COG1161, Predicted GTPases General function prediction only 76788129 Common - hypothetical protein SAK_1599 9 COG4471 COG4471, Uncharacterized protein conserved in bacteria Function unknown 76788188 Pathogen - hypothetical protein SAK_0437 1 None None None 76787649 Common glmS D-fructose-6-phosphate amidotransferase SAK_1040 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 76787959 Pathogen - hypothetical protein SAK_0292 1 None None None 76788612 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase SAK_1197 208 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 76788314 Common - Na+/H+ antiporter SAK_1059 211 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 76786959 Pathogen - hypothetical protein SAK_1963 1 None None None 76786904 Common zooA zoocin A SAK_0064 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 76787408 Common deoB phosphopentomutase SAK_1269 70 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 76786913 Common - major facilitator family transporter SAK_0894 115 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 76787254 Common - hypothetical protein SAK_0232 1 None None None 76787928 Common - hypothetical protein SAK_1154 12 COG4684 COG4684, Predicted membrane protein Function unknown 76787885 Common - transcriptional regulator, GntR family SAK_0149 177 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 76788355 Pathogen - hypothetical protein SAK_0937 1 None None None 76787478 Common pbuX xanthine permease SAK_1170 127 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 76787663 Common ribBA 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II SAK_0874 232 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 76787861 Common - hypothetical protein SAK_0820 15 COG3641 PfoR, Predicted membrane protein, putative toxin regulator General function prediction only 76788329 Common - hypothetical protein SAK_1535 39 COG2996 COG2996, Uncharacterized protein conserved in bacteria Function unknown 76787916 Common - hypothetical protein SAK_1078 28 COG2739 COG2739, Uncharacterized protein conserved in bacteria Function unknown 76788304 Common - ISSag4, transposase orfB SAK_1323 129 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 76787849 Common - nitroreductase family protein SAK_1867 28 COG3560 FMR2, Predicted oxidoreductase related to nitroreductase General function prediction only 76787128 Common - bacterial luciferase family protein SAK_1149 107 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 76788202 Common - transcriptional regulator, AraC family SAK_0775 59 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 76788423 Common - phosphate ABC transporter, phosphate-binding protein, putative SAK_1927 88 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 76787689 Common dltB dltB protein SAK_1811 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 76787365 Common rarD rarD protein SAK_1203 104 COG2962 RarD, Predicted permeases General function prediction only 76787109 Common - quaternary amine uptake (QAT) family ABC transporter, permease protein SAK_0302 195 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 76787264 Common pstA phosphate ABC transporter, permease protein PtsA SAK_1085 230 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 76788205 Pathogen - hypothetical protein SAK_0957 1 None None None 76788528 Common rpmH 50S ribosomal protein L34 SAK_1815 189 None None None 76788556 Common - hypothetical protein SAK_1670 77 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 76787765 Common - patatin-like phospholipase family protein SAK_1997 66 COG4667 COG4667, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 76787001 Common - hypothetical protein SAK_0839 4 None None None 76788449 Common - ABC transporter, permease protein SAK_0961 6 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 76787462 Common rplL 50S ribosomal protein L7/L12 SAK_1334 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 76787048 Common - ABC transporter, ATP-binding protein SAK_1371 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 76787564 Common dnaA chromosomal replication initiation protein SAK_0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 76786861 Common - 5'-nucleotidase, lipoprotein e(P4) family SAK_1789 28 COG2503 COG2503, Predicted secreted acid phosphatase General function prediction only 76787802 Common argS arginyl-tRNA synthetase SAK_2042 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 76788583 Common - peptide/opine/nickel uptake (PepT) family ABC transporter, ATP-binding protein SAK_0255 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 76788353 Common - cell wall surface anchor family protein, truncation SAK_0771 2 None None None 76786721 Common gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA SAK_2100 192 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 76788299 Pathogen - prophage LambdaSa04, tail protein, putative SAK_0757 1 COG4722 COG4722, Phage-related protein Function unknown 76787887 Common dnaG DNA primase SAK_1462 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 76786952 Common - hypothetical protein SAK_2127 6 COG3619 COG3619, Predicted membrane protein Function unknown 76787313 Common - phosphoglucomutase/phosphomannomutase family protein SAK_1155 237 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 76787294 Common - DNA polymerase III subunit epsilon SAK_1773 40 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 76788318 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase SAK_0360 228 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 76786971 Common - S4 domain protein SAK_0009 47 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 76786780 Common - DNA-binding response regulator SAK_0174 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 76787469 Pathogen - hypothetical protein SAK_0280 2 None None None 76787816 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase SAK_0063 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 76787757 Common - glyoxalase family protein SAK_2019 39 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 76787556 Common - PTS system, fructose-specific, IIB component SAK_1761 68 COG1445 FrwB, Phosphotransferase system fructose-specific component IIB Carbohydrate transport and metabolism 76787840 Common brnQ branched chain amino acid:H+ symporter SAK_1575 49 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 76786773 Common - ABC transporter, ATP-binding/permease protein SAK_0561 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 76787336 Common - integral membrane protein TIGR01906 SAK_1016 8 COG4478 COG4478, Predicted membrane protein Function unknown 76788109 Common smpB SsrA-binding protein SAK_1511 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 76787635 Common - cell wall surface anchor family protein SAK_0896 5 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 76788576 Common - hypothetical protein SAK_0770 1 None None None 76788275 Common nikA nickel ABC transporter, nickel-binding protein SAK_1542 208 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 76787695 Common tkt transketolase SAK_0350 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 76788144 Common - polar amino acid uptake (PAAT) family ABC transporter, amino acid-binding protein SAK_1044 176 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 76787976 Common pcrA ATP-dependent DNA helicase PcrA SAK_1228 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 76787775 Common - hypothetical protein SAK_0618 3 None None None 76787900 Common - hypothetical protein SAK_1876 3 None None None 76786848 Common - response regulator SAK_1918 9 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 76786787 Common - ISSag4, transposase orfB SAK_1315 138 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 76787135 Common - Cof-like hydrolase family protein SAK_2018 122 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 76787764 Common - hypothetical protein SAK_1115 9 COG4495 COG4495, Uncharacterized protein conserved in bacteria Function unknown 76788245 Common dltS sensor histidine kinase DltS SAK_1813 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76788629 Common - DNA replication intiation control protein YabA SAK_1589 15 COG4467 COG4467, Uncharacterized protein conserved in bacteria Function unknown 76788052 Common trmB tRNA (guanine-N(7))-methyltransferase SAK_0449 175 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 76787162 Common glpF glycerol uptake facilitator protein SAK_1665 132 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 76788497 Common - PRD domain protein SAK_1821 30 COG3711 BglG, Transcriptional antiterminator Transcription 76788671 Common - primase-related protein SAK_1803 21 COG1658 COG1658, Small primase-like proteins (Toprim domain) DNA replication, recombination, and repair 76787707 Common - hypothetical protein SAK_0727 13 None None None 76787579 Common - bmp family protein SAK_0478 90 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 76788414 Common rnc ribonuclease III SAK_0849 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 76788199 Pathogen - hypothetical protein SAK_0241 1 None None None 76786858 Common - hypothetical protein SAK_0864 7 COG4768 COG4768, Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain General function prediction only 76787522 Common - site-specific recombinase, phage integrase family SAK_1326 61 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 76787590 Common - transketolase, N-terminal subunit, putative SAK_0262 224 COG3959 COG3959, Transketolase, N-terminal subunit Carbohydrate transport and metabolism 76787453 Common cpsI capsular polysaccharide biosythesis protein CpsI SAK_1254 217 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 76788566 Common ecsA ABC transporter, ATP-binding protein SAK_0446 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 76787153 Common pgi glucose-6-phosphate isomerase SAK_0475 192 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 76787539 Common trmD tRNA (guanine-N(1)-)-methyltransferase SAK_1385 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 76787730 Common - hypothetical protein SAK_1904 12 COG0645 COG0645, Predicted kinase General function prediction only 76788047 Common sip group B streptococcal surface immunogenic protein SAK_0065 10 None None None 76788341 Common proB gamma-glutamyl kinase SAK_0355 190 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 76788488 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase SAK_2102 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 76787727 Common - glycosyl transferase, family 8 SAK_0936 30 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 76788190 Common cylI cylI protein SAK_0799 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 76787183 Common - hypothetical protein SAK_1280 31 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 76788440 Common - cytidine/deoxycytidylate deaminase family protein SAK_0474 210 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 76787700 Pathogen - hypothetical protein SAK_1114 1 None None None 76788116 Common yajC preprotein translocase subunit YajC SAK_1875 7 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 76787504 Common - cell wall surface anchor family protein SAK_0466 2 None None None 76788005 Pathogen - prophage LambdaSa03, structural protein, putative SAK_0637 1 None None None 76788114 Common - DRTGG domain/CBS domain protein SAK_0968 21 COG4109 COG4109, Predicted transcriptional regulator containing CBS domains Transcription 76788359 Common - methyltransferase domain protein SAK_1047 125 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 76787053 Common - hypothetical protein SAK_1738 2 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 76788647 Common engA GTP-binding protein EngA SAK_1634 227 COG1160 COG1160, Predicted GTPases General function prediction only 76788471 Common neuC UDP-N-acetylglucosamine-2-epimerase NeuC SAK_1249 61 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 76787203 Common - dihydroxyacetone kinase DAK2 domain protein SAK_1663 76 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 76786796 Common - phosphoglycerate mutase family protein SAK_0878 114 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 76788609 Common - hydrolase, NUDIX family SAK_1282 27 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 76788010 Common groES co-chaperonin GroES SAK_2014 198 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 76787944 Common - collagen-like surface protein, putative SAK_0722 62 None None None 76787354 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 family protein SAK_0877 102 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 76786763 Pathogen - lipoprotein, putative SAK_0321 1 None None None 76786888 Common - organic hydroperoxide resistance protein, putative SAK_0680 25 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 76788533 Common - transcriptional regulator, GntR family SAK_1034 109 COG1725 COG1725, Predicted transcriptional regulators Transcription 76787873 Common - DNA-binding response regulator SAK_0467 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 76788015 Common - peptidase, U61 (muramoyl-tetrapeptide carboxypeptidase) family SAK_1858 82 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 76787785 Common pyrR pyrimidine regulatory protein PyrR SAK_1397 109 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 76788403 Common - transcriptional regulator, AraC family SAK_0516 120 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 76788368 Common aroB 3-dehydroquinate synthase SAK_1411 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 76788664 Common asp3 accessory secretory protein Asp3 SAK_1483 5 None None None 76787487 Common - hypothetical protein SAK_1931 14 COG4815 COG4815, Uncharacterized protein conserved in bacteria Function unknown 76787530 Common - carbamoyl-phosphate synthase, large subunit, putative SAK_1395 229 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 76787025 Common aroC chorismate synthase SAK_1410 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 76788237 Common prfA peptide chain release factor 1 SAK_1163 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 76787413 Common - transcriptional regulator, TetR family SAK_0515 24 COG1309 AcrR, Transcriptional regulator Transcription 76787720 Common - prophage LambdaSa04, LysM domain protein SAK_0762 33 COG3858 COG3858, Predicted glycosyl hydrolase General function prediction only 76788642 Common - hypothetical protein SAK_0633 3 None None None 76787915 Common - glycine betaine transporter OpuD, interruption-C SAK_1207 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 76787750 Common - ABC transporter, ATP-binding protein SAK_0812 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 76786945 Common comX competence-specific sigma factor ComX SAK_0141 5 None None None 76786746 Common - sensor histidine kinase SAK_1993 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76788466 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase SAK_0160 176 COG0756 Dut, dUTPase Nucleotide transport and metabolism 76787324 Common pyrD dihydroorotate dehydrogenase 1A SAK_0657 234 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 76787665 Common - hypothetical protein SAK_1301 19 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 76787237 Common - hypothetical protein SAK_0754 4 None None None 76788685 Common - efflux transporter, RND family, MFP subunit SAK_1394 121 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 76788301 Common - peptidase, U32 (collagenase) family SAK_0868 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 76787262 Common - iron-dependent repressor SAK_1557 80 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 76787303 Common - hypothetical protein SAK_0609 2 None None None 76787039 Common - hypothetical protein SAK_0732 14 None None None 76787286 Common livM hydrophobic amino acid uptake (HAAT) family ABC transporter, permease protein LivM SAK_1596 157 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 76787107 Pathogen - hypothetical protein SAK_0939 1 None None None 76788503 Common - GcvH family protein SAK_1148 87 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 76787432 Common acpS 4'-phosphopantetheinyl transferase SAK_1697 143 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 76788683 Common - DNA-binding response regulator SAK_1111 177 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 76786999 Common - D-mannonate oxidoreductase SAK_0829 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 76787378 Common - PTS system, IIC component, putative SAK_1825 19 COG3775 GatC, Phosphotransferase system, galactitol-specific IIC component Carbohydrate transport and metabolism 76787195 Common - transcriptional regulator, RofA family SAK_1389 3 None None None 76788292 Common lgt prolipoprotein diacylglyceryl transferase SAK_0863 209 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 76787171 Common gidB glucose-inhibited division protein B SAK_1643 195 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 76787895 Common - glycerol dehydrogenase, putative SAK_1985 81 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 76788181 Common - hypothetical protein SAK_1774 2 None None None 76786990 Common nth endonuclease III SAK_0570 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 76787737 Common thrC threonine synthase SAK_0088 138 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 76786914 Common - ISSag4, transposase orfA SAK_1322 29 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 76787626 Common sdhB L-serine dehydratase, iron-sulfur-dependent, beta subunit SAK_2103 150 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 76786813 Pathogen - hypothetical protein SAK_0623 1 None None None 76787144 Common - carbohydrate uptake 2 (CUT2) family, permease protein SAK_1051 127 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 76787831 Pathogen cylX cylX protein SAK_0790 1 None None None 76788457 Common tlyA hemolysin A SAK_0600 131 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 76787862 Common - hypothetical protein SAK_1409 16 COG3679 COG3679, Uncharacterized conserved protein Function unknown 76787007 Common - hypothetical protein SAK_1718 8 COG4858 COG4858, Uncharacterized membrane-bound protein conserved in bacteria Function unknown 76787383 Common - arginine/ornithine antiporter SAK_2124 115 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 76787619 Pathogen - hypothetical protein SAK_1733 1 None None None 76788025 Common - hypothetical protein SAK_1573 17 COG1285 SapB, Uncharacterized membrane protein Function unknown 76788061 Common - replication initiation factor family protein SAK_0284 3 COG2946 COG2946, Putative phage replication protein RstA DNA replication, recombination, and repair 76788656 Common - ABC transporter, ATP-binding protein SAK_1274 249 COG1101 PhnK, ABC-type uncharacterized transport system, ATPase component General function prediction only 76787913 Pathogen - hypothetical protein SAK_1711 1 None None None 76787125 Common - radical SAM protein, TIGR01212 family SAK_1434 74 COG1242 COG1242, Predicted Fe-S oxidoreductase General function prediction only 76787678 Common - hypothetical protein SAK_0632 2 None None None 76786960 Common - SUF system FeS assembly protein, NifU family SAK_0202 163 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 76787427 Common murI glutamate racemase SAK_1615 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 76787948 Common - hypothetical protein SAK_0959 20 COG4721 COG4721, Predicted membrane protein Function unknown 76787848 Pathogen - hypothetical protein SAK_0324 1 None None None 76787343 Common - sensor histidine kinase SAK_0380 106 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 76788363 Common - glycosyl transferase, group 2 family protein SAK_1456 164 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 76788126 Common purB adenylosuccinate lyase SAK_0080 239 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 76787869 Common - hypothetical protein SAK_0729 8 None None None 76787377 Pathogen - hypothetical protein SAK_0830 4 COG0546 Gph, Predicted phosphatases General function prediction only 76788257 Common - ISSag6, transposase orfA SAK_0695 6 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 76787246 Common purA adenylosuccinate synthetase SAK_1838 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 76787283 Common prs ribose-phosphate pyrophosphokinase SAK_0051 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 76787736 Common - conserved hypothetical protein TIGR00150 SAK_0440 197 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 76787653 Common - drug:H+ antiporter-2 (DHA2) family protein SAK_1716 179 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 76786788 Common - sensor histidine kinase SAK_1358 208 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76788455 Common - sensor histidine kinase, putative SAK_1907 102 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 76787256 Common - VanZ family protein SAK_0560 1 COG4767 VanZ, Glycopeptide antibiotics resistance protein Defense mechanisms 76786875 Common - hypothetical protein SAK_1419 1 None None None 76788610 Common - PTS system, galactitol-specific IIA component, putative SAK_0524 21 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 76788317 Common - glyoxylase family protein SAK_1057 47 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 76788474 Common - K+ uptake permease (KUP) family protein SAK_1175 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 76787503 Common folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase SAK_1198 203 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 76787096 Common ribE riboflavin synthase subunit alpha SAK_0873 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 76787981 Common ahpC alkyl hydroperoxide reductase, subunit C SAK_1853 216 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 76788600 Common - glycosyl transferase, family 8 SAK_1490 35 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 76787829 Common ezrA septation ring formation regulator EzrA SAK_0709 32 COG4477 EzrA, Negative regulator of septation ring formation Cell division and chromosome partitioning 76788663 Common - PTS system, IIB component, lactose/cellobiose family SAK_0399 31 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 76787952 Common ilvE branched-chain amino acid aminotransferase SAK_1241 197 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 76788228 Common add adenosine deaminase SAK_0688 109 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 76788581 Common - polar amino acid uptake (PAAT) family ABC transporter, substrate-binding/permease protein SAK_1497 190 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 76787490 Common - chromosome partition protein, ParB family SAK_2136 188 COG1475 Spo0J, Predicted transcriptional regulators Transcription 76787546 Common - ComG operon protein 2, putative SAK_0227 83 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 76788479 Common adcR adc operon repressor AdcR SAK_0217 7 COG1846 MarR, Transcriptional regulators Transcription 76786925 Common glyQ glycyl-tRNA synthetase subunit alpha SAK_0340 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 76787141 Common argR arginine repressor SAK_2041 77 COG1438 ArgR, Arginine repressor Transcription 76787117 Pathogen - hypothetical protein SAK_1964 1 None None None 76786866 Common msmK sugar ABC transporter, ATP-binding protein SAK_1884 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 76788305 Common - prophage LambdaSa03, terminase, large subunit, putative SAK_0635 5 COG4626 COG4626, Phage terminase-like protein, large subunit General function prediction only 76786894 Common - transcriptional regulator, DeoR family SAK_0396 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 76788658 Common uppP undecaprenyl pyrophosphate phosphatase SAK_0196 199 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 76788211 Common - hypothetical protein SAK_1012 6 None None None 76787927 Common - pyridine nucleotide-disulphide oxidoreductase family protein SAK_1384 247 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 76787214 Common polC DNA polymerase III PolC SAK_1869 216 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 76786969 Common - hypothetical protein SAK_1840 38 COG2964 COG2964, Uncharacterized protein conserved in bacteria Function unknown 76788619 Common aspS aspartyl-tRNA synthetase SAK_2046 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 76788081 Common - pyridine nucleotide-disulphide oxidoreductase family protein SAK_1751 211 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 76788380 Common - major facilitator family protein SAK_1996 168 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 76787441 Pathogen - hypothetical protein SAK_0634 1 None None None 76788312 Common pabB para-aminobenzoate synthase, component I SAK_1551 223 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 76787718 Common - cyclodextrin ABC transporter, permease protein SAK_1477 161 COG3833 MalG, ABC-type maltose transport systems, permease component Carbohydrate transport and metabolism 76786931 Common - putative translaldolase SAK_1829 172 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 76788033 Common - coproporphyrinogen III oxidase SAK_1013 208 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 76786835 Common - hypothetical protein SAK_1436 18 COG3601 COG3601, Predicted membrane protein Function unknown 76787000 Common arcA arginine deiminase SAK_2121 56 COG2235 ArcA, Arginine deiminase Amino acid transport and metabolism 76786899 Pathogen - hypothetical protein SAK_1866 1 None None None 76787068 Common - glycosyl transferase, group 2 family protein SAK_1488 194 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 76786806 Common - pullulanase, extracellular SAK_1302 154 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 76788465 Common folB dihydroneopterin aldolase SAK_1199 105 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 76788526 Common - RelA/SpoT domain protein SAK_1180 105 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 76786756 Common - isoprenylcysteine carboxyl methyltransferase (ICMT) family protein SAK_0187 17 COG1755 COG1755, Uncharacterized protein conserved in bacteria Function unknown 76788280 Common cdd cytidine deaminase SAK_1048 118 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 76788490 Common pstB phosphate ABC transporter, ATP-binding protein PstB SAK_1084 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 76788182 Common - PAP2 family protein SAK_1435 77 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 76786846 Common - N-acetylneuraminate lyase, putative SAK_0072 232 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 76786906 Common pstA phosphate ABC transporter, permease protein PtsA SAK_1925 225 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 76788398 Pathogen - hypothetical protein SAK_1961 1 None None None 76788394 Common - response regulator SAK_1881 74 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 76787883 Common - ISSag4, transposase orfA SAK_1314 29 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 76787044 Common tgt queuine tRNA-ribosyltransferase SAK_0470 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 76787172 Common - polar amino acid uptake (PAAT) family ABC transporter, amino acid-binding protein SAK_1466 184 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 76787788 Common uppS undecaprenyl diphosphate synthase SAK_1874 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 161486742 Common proS prolyl-tRNA synthetase SAK_1871 235 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 76788665 Common - hypothetical protein SAK_1125 3 COG5417 COG5417, Uncharacterized small protein Function unknown 76788632 Common - hypothetical protein SAK_0807 44 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 76787220 Common rpsG 30S ribosomal protein S7 SAK_1792 249 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 76787623 Common - hypothetical protein SAK_1822 14 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 76787227 Common - polar amino acid uptake (PAAT) family ABC transporter, ATP-binding protein SAK_1498 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 76788412 Common divIB cell division protein DivIB SAK_0579 10 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 76788594 Common - hypothetical protein SAK_0817 70 COG0390 COG0390, ABC-type uncharacterized transport system, permease component General function prediction only 76788389 Common - peptidase, M50A (S2P peptidase) subfamily SAK_1872 205 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 76787081 Common - oligopeptide ABC transporter, oligopeptide-binding protein, putative SAK_0206 190 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 76788617 Common - ArsC family protein SAK_1582 27 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 76787744 Common - ABC transporter, permease protein Vexp3 SAK_0700 17 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 76788173 Common pnp polynucleotide phosphorylase/polyadenylase SAK_0266 237 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 76787820 Common - hypothetical protein SAK_1666 20 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 76788124 Common - PAP2 family protein SAK_1978 33 None None None 76788077 Common trmE tRNA modification GTPase TrmE SAK_0999 217 COG0486 ThdF, Predicted GTPase General function prediction only 76788276 Common lepB signal peptidase I SAK_1038 71 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 76787234 Common scrR sucrose operon repressor ScrR SAK_1704 129 COG1609 PurR, Transcriptional regulators Transcription 76788454 Common thrB homoserine kinase SAK_1204 122 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 76786991 Pathogen - hypothetical protein SAK_0079 1 None None None 76786795 Common - hypothetical protein SAK_0195 6 COG4907 COG4907, Predicted membrane protein Function unknown 76788169 Common - hypothetical protein SAK_0882 13 COG1928 PMT1, Dolichyl-phosphate-mannose--protein O-mannosyl transferase Posttranslational modification, protein turnover, chaperones 76787758 Common - transcriptional regulator, TetR family SAK_0332 72 COG1309 AcrR, Transcriptional regulator Transcription 76786973 Common - hypothetical protein SAK_1739 11 COG0730 COG0730, Predicted permeases General function prediction only 76787671 Common - ABC transporter, ATP-binding protein SAK_0816 249 COG4619 COG4619, ABC-type uncharacterized transport system, ATPase component General function prediction only 76787703 Common - thioesterase, Acyl-ACP family SAK_1014 23 COG3884 FatA, Acyl-ACP thioesterase Lipid metabolism 76787322 Common - hypothetical protein SAK_2081 2 None None None 76787856 Pathogen - hypothetical protein SAK_0856 1 None None None 76786737 Common parE DNA topoisomerase IV subunit B SAK_1243 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 76788495 Common rplS 50S ribosomal protein L19 SAK_0692 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 76786980 Common rpsE 30S ribosomal protein S5 SAK_0108 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 76787563 Common - conserved hypothetical protein TIGR00147 SAK_1351 115 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 76788191 Common - CAAX amino terminal protease family protein SAK_1981 19 None None None 76788332 Common rfbA glucose-1-phosphate thymidylyltransferase SAK_1287 234 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 76787100 Common - hypothetical protein SAK_0923 53 COG1814 COG1814, Uncharacterized membrane protein Function unknown 76786918 Common pepB group B oligopeptidase PepB SAK_0929 85 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 76788695 Common - lactose phosphotransferase system repressor, putative SAK_1896 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 76788377 Common - prophage LambdaSa04, terminase, small subunit, P27 family SAK_0741 19 COG3747 COG3747, Phage terminase, small subunit DNA replication, recombination, and repair 76787584 Common - hypothetical protein SAK_0139 23 COG3575 COG3575, Uncharacterized protein conserved in bacteria Function unknown 76788104 Common - hypothetical protein SAK_0374 133 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 76787680 Common endA DNA-entry nuclease SAK_0991 5 None None None 76787518 Pathogen - cell wall surface anchor family protein SAK_1493 2 COG5422 ROM1, RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases Signal transduction mechanisms 76788692 Common - peptidase, M42 (glutamyl aminopeptidase) family SAK_1903 84 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 76788044 Common - CBS domain protein SAK_1684 22 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 76787664 Common - hypothetical protein SAK_1617 4 None None None 76787768 Common - glycosyl transferase, family 8 SAK_1491 29 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 76787572 Common - DNA-binding protein SAK_0326 66 COG1476 COG1476, Predicted transcriptional regulators Transcription 76787499 Pathogen - hypothetical protein SAK_2080 1 None None None 76787682 Common pgsA CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase SAK_2110 206 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 76787376 Common - membrane protein, Bmp family SAK_1049 83 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 76787872 Common - sensor histidine kinase SAK_0188 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76788425 Common pepN aminopeptidase N SAK_1081 165 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 76787633 Common - DNA-binding protein, Fis family SAK_1885 10 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 76788509 Common pepC aminopeptidase C SAK_0369 16 COG3579 PepC, Aminopeptidase C Amino acid transport and metabolism 76787304 Common deoC deoxyribose-phosphate aldolase SAK_2009 138 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 76788548 Pathogen - hypothetical protein SAK_1340 1 None None None 76787998 Common - hypothetical protein SAK_1850 17 COG2426 COG2426, Predicted membrane protein Function unknown 76788486 Common - MORN repeat family protein SAK_0084 25 COG4642 COG4642, Uncharacterized protein conserved in bacteria Function unknown 76787164 Common pth peptidyl-tRNA hydrolase SAK_0007 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 76786943 Common - glycosyl transferase, group 2 family protein SAK_1509 201 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 76787577 Common - hypothetical protein SAK_2045 55 COG1284 COG1284, Uncharacterized conserved protein Function unknown 76787035 Common - hypothetical protein SAK_0933 7 COG4894 COG4894, Uncharacterized conserved protein Function unknown 76788008 Common - conserved hypothetical protein TIGR00253 SAK_1675 93 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 76787628 Common nagA N-acetylglucosamine-6-phosphate deacetylase SAK_0338 118 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 76787701 Common - hypothetical protein SAK_0576 1 None None None 76787991 Pathogen - hypothetical protein SAK_1522 1 None None None 76787272 Common - MutS2 family protein SAK_1727 205 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 76787180 Common - hydrolase, HAD subfamily IIIA SAK_1677 43 COG2179 COG2179, Predicted hydrolase of the HAD superfamily General function prediction only 76787777 Common - carbohydrate uptake 1 (CUT1) family ABC transporter, permease protein SAK_0069 155 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 76786728 Common - sortase family protein SAK_0779 20 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 76787937 Common - HD domain protein SAK_1024 60 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 76788515 Common - transcriptional regulator, TetR family SAK_1341 14 COG1309 AcrR, Transcriptional regulator Transcription 76787457 Pathogen - hypothetical protein SAK_1126 1 None None None 76787433 Common - quaternary amine uptake (QAT) family ABC transporter, permease protein SAK_0300 149 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 76788644 Common ppdK pyruvate phosphate dikinase SAK_1682 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 76786997 Common - sensor histidine kinase SAK_1112 104 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 76787725 Common lplA lipoate-protein ligase A SAK_1145 69 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 76787185 Common - prophage LambdaSa03, transcriptional regulator, Cro/CI family SAK_0610 3 COG1396 HipB, Predicted transcriptional regulators Transcription 76787042 Common - hypothetical protein SAK_1935 2 COG4043 COG4043, Uncharacterized conserved protein Function unknown 76787015 Common - peptidase, M20D (carboxypeptidase Ss1) subfamily SAK_1547 168 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 76787485 Common cdsA phosphatidate cytidylyltransferase SAK_1873 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 76787484 Common rgfB RgfB protein SAK_1919 4 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 76786716 Common - oxidoreductase, FAD-binding SAK_1288 54 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 76788184 Common - conserved hypothetical protein TIGR00044 SAK_0582 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 76788607 Pathogen - hypothetical protein SAK_1516 1 None None None 76787102 Pathogen - hypothetical protein SAK_0638 1 None None None 76787055 Pathogen - hypothetical protein SAK_0649 1 None None None 76788289 Common - PTS system, IIB component, lactose/cellobiose family SAK_0260 28 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 76786873 Common - hypothetical protein SAK_1130 3 COG5153 CVT17, Putative lipase essential for disintegration of autophagic bodies inside the vacuole Intracellular trafficking and secretion / Lipid metabolism 76787119 Common - hypothetical protein SAK_1571 7 None None None 76787418 Common - hypothetical protein SAK_1433 28 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 76787987 Common - hydrolase, NUDIX family SAK_0589 16 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 76787723 Common - chloride channel (ClC) family protein SAK_1266 145 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 76787960 Common tkt transketolase SAK_1756 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 76786793 Common tpx thiol peroxidase SAK_1217 120 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 76786978 Common - hypothetical protein SAK_1455 15 COG2456 COG2456, Uncharacterized conserved protein Function unknown 76787532 Pathogen - hypothetical protein SAK_1710 1 None None None 76787751 Common - conserved hypothetical protein TIGR00046 SAK_1929 171 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 76787642 Common - ABC transporter, permease protein SAK_0333 156 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 76788561 Common - HAD-superfamily hydrolase, subfamily IIA SAK_1015 106 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 76788531 Pathogen - hypothetical protein SAK_1039 1 None None None 76788164 Common mfd transcription-repair coupling factor SAK_0008 229 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 76787975 Common - ISSag9, transposase SAK_1592 37 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 76787382 Common rbgA ribosomal biogenesis GTPase SAK_1108 172 COG1161 COG1161, Predicted GTPases General function prediction only 76787208 Common - hypothetical protein SAK_0181 40 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 76787352 Common arcC carbamate kinase SAK_2064 67 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 76787558 Common - sensor histidine kinase VncS, putative SAK_0702 114 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76787621 Common - DNA internalization-related competence protein ComEC/Rec2 SAK_0907 138 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 76788409 Common pyrC dihydroorotase SAK_1135 212 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 76787140 Common - MATE efflux family protein SAK_1310 154 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 76788146 Common fni isopentenyl pyrophosphate isomerase SAK_1354 81 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 76787291 Common - membrane protein oxaA, putative SAK_0482 213 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 76787451 Common - DNA-binding protein SAK_0938 70 COG1476 COG1476, Predicted transcriptional regulators Transcription 76787897 Common lepB signal peptidase I SAK_1731 118 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 76787693 Common mutX mutator mutT protein SAK_1283 35 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 76787155 Common dnaJ co-chaperone protein DnaJ SAK_0148 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 76787088 Common - Cof-like hydrolase SAK_0852 126 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 76788527 Common - hypothetical protein SAK_0454 20 COG1358 RPL8A, Ribosomal protein HS6-type (S12/L30/L7a) Translation, ribosomal structure and biogenesis 76786948 Common - amino acid ABC transporter, ATP-binding protein, putative SAK_0899 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 76788139 Common - hypothetical protein SAK_0004 26 COG4481 COG4481, Uncharacterized protein conserved in bacteria Function unknown 76788539 Common mtsC metal ABC transporter, permease protein SAK_1554 190 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 76787475 Common - hypothetical protein SAK_1568 2 COG3760 COG3760, Uncharacterized conserved protein Function unknown 76787281 Common - acetyltransferase, GNAT family SAK_1933 9 COG3153 COG3153, Predicted acetyltransferase General function prediction only 76787154 Common - efflux ABC transporter, permease/ATP-binding protein SAK_1362 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 161486743 Common rpsK 30S ribosomal protein S11 SAK_0115 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 76787846 Common - hypothetical protein SAK_0898 29 None None None 76788137 Common thiM hydroxyethylthiazole kinase SAK_0964 77 COG2145 ThiM, Hydroxyethylthiazole kinase, sugar kinase family Coenzyme metabolism 76787943 Common - D-alanyl-D-alanine carboxypeptidase SAK_0205 139 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 76788279 Common glpO glycerol-3-phosphate oxidase SAK_0346 149 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 76786834 Common - IS1381 transposase protein A SAK_0540 5 None None None 76787566 Common rpoA DNA-directed RNA polymerase subunit alpha SAK_0116 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 76787798 Common - calcium-transporting ATPase, P-type (transporting), HAD superfamily, subfamily IC SAK_0664 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 76788303 Common - PTS system, IIA component SAK_1833 40 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 76787193 Pathogen - cell wall surface anchor family protein SAK_1503 1 None None None 76788232 Common - thioredoxin family protein SAK_0243 88 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 76788572 Common tpiA triosephosphate isomerase SAK_0888 216 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 76788320 Common cydD ABC transporter, ATP-binding protein CydD SAK_1748 249 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 76788433 Common - hypothetical protein SAK_2026 3 None None None 76786757 Pathogen - hypothetical protein SAK_1842 1 None None None 76787886 Common - CutC family protein SAK_1587 55 COG3142 CutC, Uncharacterized protein involved in copper resistance Inorganic ion transport and metabolism 76788036 Common - carbohydrate uptake 1 (CUT1) family, carbohydrate-binding protein SAK_1475 66 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 76788673 Common - ABC transporter, substrate-binding protein SAK_1905 130 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 76786843 Common rpsH 30S ribosomal protein S8 SAK_0105 248 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 76787270 Common rnhC ribonuclease HIII SAK_1730 34 COG1039 RnhC, Ribonuclease HIII DNA replication, recombination, and repair 76788568 Common purN phosphoribosylglycinamide formyltransferase SAK_0061 220 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 76787834 Common - hypothetical protein SAK_1184 7 None None None 76787464 Common cydA cytochrome d ubiquinol oxidase, subunit II SAK_1750 167 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 76788092 Common - S1 RNA binding domain protein SAK_0858 189 COG2183 Tex, Transcriptional accessory protein Transcription 76786950 Common - amidase SAK_1626 217 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 76787134 Common - transcriptional regulator, MarR family SAK_0921 95 COG1846 MarR, Transcriptional regulators Transcription 76786826 Pathogen - hypothetical protein SAK_0956 1 None None None 76788520 Common arb 6-phospho-beta-glucosidase SAK_1188 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 76787056 Common - cell division protein FtsL, putative SAK_0358 5 COG4839 FtsL, Protein required for the initiation of cell division Cell division and chromosome partitioning 76788223 Common - sensor histidine kinase, putative SAK_1880 41 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 76788344 Common - hypothetical protein SAK_0672 13 COG2267 PldB, Lysophospholipase Lipid metabolism 76788333 Common - prophage LambdaSa04, minor structural protein, putative SAK_0759 2 COG4675 MdpB, Microcystin-dependent protein Function unknown 76786743 Common - ABC transporter, ATP-binding protein SAK_0173 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 76787801 Common fabH 3-oxoacyl-(acyl carrier protein) synthase III SAK_0418 219 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 76788268 Common aroA 3-phosphoshikimate 1-carboxyvinyltransferase SAK_0715 232 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 76786956 Common - sugar ABC transporter, permease protein, putative SAK_0533 144 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 76787812 Common - hypothetical protein SAK_0448 10 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 76787932 Common - PTS system, sucrose-specific IIABC component SAK_1702 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 76787603 Common sun sun protein SAK_0387 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 76788270 Common - hypothetical protein SAK_1968 11 None None None 76788130 Common - aminotransferase AlaT SAK_1688 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 76787523 Common - tetrapyrrole methylase family protein SAK_1588 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 76788297 Common - phenazine biosynthesis protein, PhzF family SAK_1767 119 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 76787814 Common - polar amino acid uptake (PAAT) family ABC transporter, permease protein SAK_1624 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 76787770 Common - replication initiation factor, RepA family SAK_0282 8 COG2188 PhnF, Transcriptional regulators Transcription 76787335 Pathogen - hypothetical protein SAK_0785 1 None None None 76787589 Common - conserved hypothetical protein FRAMESHIFT SAK_2128 45 COG1284 COG1284, Uncharacterized conserved protein Function unknown 76788290 Pathogen - hypothetical protein SAK_0731 1 None None None 76788365 Common - hypothetical protein SAK_2082 1 None None None 76788551 Common - Cof-like hydrolase family protein SAK_0908 115 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 76787879 Common - polar amino acid uptake (PAAT) family ABC transporter, amino acid-binding protein SAK_0362 134 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 76788700 Common xerS site-specific tyrosine recombinase XerS SAK_1073 214 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 76787907 Common - GTP-binding protein SAK_1298 220 COG2262 HflX, GTPases General function prediction only 76788178 Common - iron compound ABC transporter, permease protein SAK_1428 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 76786828 Common - hypothetical protein SAK_0663 2 COG4506 COG4506, Uncharacterized protein conserved in bacteria Function unknown 76787260 Common - glycosyl transferase, group 2 family protein SAK_1570 156 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 76788322 Common - TENA/THI-4 family protein SAK_0962 59 COG0819 TenA, Putative transcription activator Transcription 76787666 Common - tetracenomycin polyketide synthesis O-methyltransferase TcmP, putative SAK_1528 34 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 76788206 Common pstB phosphate ABC transporter, ATP-binding protein SAK_1924 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 76788661 Common scpB C5a peptidase ScpB SAK_1320 66 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 76788370 Common - cna B-type domain protein SAK_1441 10 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 76786868 Common cpdB 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase bifunctional periplasmic precursor protein SAK_1901 133 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 76787881 Common - hypothetical protein SAK_1957 2 None None None 76787610 Common - oxidoreductase, NAD-binding SAK_1860 159 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 76788243 Pathogen - hypothetical protein SAK_0656 1 None None None 76787719 Common fabZ (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase SAK_0425 188 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 76788430 Pathogen cylE CylE protein SAK_0797 1 None None None 76786892 Common - pyridine nucleotide-disulfide oxidoreductase SAK_0348 208 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 76788310 Common budB acetolactate synthase SAK_1279 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 76787954 Common atpC F0F1 ATP synthase subunit epsilon SAK_0987 124 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 76788379 Common glgP glycogen/starch/alpha-glucan phosphorylase SAK_1472 148 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 76787181 Common - transcriptional regulator, GntR family SAK_0825 143 COG2186 FadR, Transcriptional regulators Transcription 76787473 Common - sugar-binding transcriptional regulator, LacI family SAK_0909 128 COG1609 PurR, Transcriptional regulators Transcription 76787696 Common - hypothetical protein SAK_0712 1 COG5506 COG5506, Uncharacterized conserved protein Function unknown 76787310 Common - integral membrane protein SAK_1678 165 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 76788351 Common purF amidophosphoribosyltransferase SAK_0059 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 76787868 Common accC acetyl-CoA carboxylase biotin carboxylase subunit SAK_0426 237 COG0439 AccC, Biotin carboxylase Lipid metabolism 76788213 Common - hypothetical protein SAK_1808 2 None None None 76786837 Common - D-3-phosphoglycerate dehydrogenase, putative SAK_1584 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 76787716 Common - ATP-dependent RNA helicase, DEAD/DEAH box family SAK_0361 238 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 76786802 Common - PTS system, fructose-specific, IIC component SAK_1759 67 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 76786740 Common folC folylpolyglutamate synthase SAK_1202 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 76787098 Common prfB peptide chain release factor 2 SAK_0668 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 76788625 Common rimI ribosomal-protein-alanine acetyltransferase SAK_1780 148 COG0456 RimI, Acetyltransferases General function prediction only 76787124 Common - ABC transporter, ATP-binding/permease protein SAK_1369 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 76786747 Common pepA glutamyl aminopeptidase SAK_0240 81 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 76787031 Common - hypothetical protein SAK_0682 91 COG0391 COG0391, Uncharacterized conserved protein Function unknown 76786808 Common ldhA D-lactate dehydrogenase SAK_0821 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 76788255 Common - PTS system, trehalose-specific IIBCA component SAK_0257 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 76788524 Common - D-isomer specific 2-hydroxyacid dehydrogenase family protein SAK_1826 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 76787086 Common - hypothetical protein SAK_1353 1 None None None 76786739 Common purE phosphoribosylaminoimidazole carboxylase catalytic subunit SAK_0077 233 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 76788286 Common - cytoplasmic alpha-amylase SAK_0834 103 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 76787361 Common - peptidase M16 inactive domain protein SAK_2112 90 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 76788667 Common spxA transcriptional regulator Spx SAK_2031 42 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 76787401 Common rplW 50S ribosomal protein L23 SAK_0093 188 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 76787349 Common pepT peptidase T SAK_1422 60 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 76787988 Common - DegV family protein SAK_1373 53 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 76787342 Common ksgA dimethyladenosine transferase SAK_1801 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 76788651 Common galU UTP-glucose-1-phosphate uridylyltransferase SAK_0479 232 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 76787219 Common - leucine-rich repeat protein SAK_1023 33 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 76787229 Common - acetyltransferase, GNAT family SAK_0328 111 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 76787425 Common - alpha amylase family protein SAK_0258 159 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 76787925 Common rluB ribosomal large subunit pseudouridine synthase B SAK_1608 207 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 76788587 Common fibB beta-lactam resistance factor SAK_0658 11 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 76787658 Pathogen - hypothetical protein SAK_1827 2 None None None 76788064 Common - dihydroxyacetone kinase DAK1 domain protein SAK_1662 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 76787822 Common tuf elongation factor Tu SAK_0887 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 76787651 Common nadE NAD synthetase SAK_0368 158 COG0171 NadE, NAD synthase Coenzyme metabolism 76786761 Common - RNA methyltransferase, TrmH family SAK_1603 156 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 76788153 Common - YbaK/EbsC family protein SAK_0879 96 COG2606 EbsC, Uncharacterized conserved protein Function unknown 76788128 Common - hypothetical protein SAK_1944 6 None None None 76787258 Common argF ornithine carbamoyltransferase SAK_2065 238 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 76787637 Common stp1 serine/threonine protein phosphatase Stp1 SAK_0388 134 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 76787338 Common - PTS system, galactitol-specific IIC component SAK_0529 19 COG3775 GatC, Phosphotransferase system, galactitol-specific IIC component Carbohydrate transport and metabolism 76787493 Common rbsR ribose operon repressor SAK_0171 126 COG1609 PurR, Transcriptional regulators Transcription 76787902 Common - ISSag8, transposase SAK_0320 56 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 76787962 Common - prophage Sa05, BRO domain protein SAK_2089 5 COG3646 COG3646, Uncharacterized phage-encoded protein Function unknown 76787320 Common - hypothetical protein SAK_2020 77 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 76788592 Common - prophage LambdaSa04, methyltransferase, C-5 cytosine-specific family SAK_0739 123 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 76788469 Common - Holliday junction resolvase-like protein SAK_2029 184 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 76786822 Common rpmG 50S ribosomal protein L33 SAK_2049 82 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 76787065 Common glgB glycogen branching enzyme SAK_0976 147 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 76788705 Common - Clostridial hydrophobic W repeat protein SAK_1293 13 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 76788402 Common - hypothetical protein SAK_0972 15 COG4708 COG4708, Predicted membrane protein Function unknown 76788502 Common - hypothetical protein SAK_0789 34 COG3694 COG3694, ABC-type uncharacterized transport system, permease component General function prediction only 76788013 Common - polar amino acid uptake (PAAT) family ABC transporter, amino acid-binding protein SAK_0843 174 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 76787492 Common - D-alanyl-D-alanine carboxypeptidase SAK_0204 147 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 76788702 Common - ribonucleotide-diphosphate reductase subunit alpha SAK_0501 222 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 76788265 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase SAK_0422 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 76787673 Common - hypothetical protein SAK_0379 37 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 76786938 Common - ABC transporter, permease protein EcsB, putative SAK_0447 12 COG4473 EcsB, Predicted ABC-type exoprotein transport system, permease component Intracellular trafficking and secretion 76787604 Common - ABC transporter, permease protein, putative SAK_1098 40 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 76787844 Common - ABC transporter, ATP-binding protein SAK_0787 249 COG4586 COG4586, ABC-type uncharacterized transport system, ATPase component General function prediction only 76788330 Common carA carbamoyl phosphate synthase small subunit SAK_1133 238 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 76787036 Common - ABC transporter, permease protein, putative SAK_1392 188 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 76787505 Common - prophage Sa05, site-specific recombinase, phage integrase family SAK_2094 136 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 76787398 Common - amino acid/peptide transporter SAK_1478 82 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 76788088 Common nikB nickel ABC transporter, permease protein SAK_1541 218 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 76787009 Common - hypothetical protein SAK_1011 6 COG3272 COG3272, Uncharacterized conserved protein Function unknown 76788046 Common - K+ transporter (Trk) family protein SAK_1644 84 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 76787570 Common rpsN 30S ribosomal protein S14 SAK_1777 203 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 76788690 Common - phosphomethylpyrimidine kinase SAK_0151 219 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 76786989 Common - hypothetical protein SAK_0752 5 None None None 76787279 Common - CBS domain protein SAK_1612 13 COG0517 COG0517, FOG: CBS domain General function prediction only 76786754 Common - prophage LambdaSa04, tail tape measure protein, TP901 family SAK_0756 47 COG5280 COG5280, Phage-related minor tail protein Function unknown 76787066 Common - hypothetical protein SAK_1096 10 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 76787350 Common oppD oligopeptide ABC transporter, ATP-binding protein SAK_0209 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 76787232 Common - hypothetical protein SAK_0492 17 COG3557 COG3557, Uncharacterized domain/protein associated with RNAses G and E Translation, ribosomal structure and biogenesis 76788615 Common - ABC transporter, permease protein, putative SAK_1070 17 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 76788475 Common - hypothetical protein SAK_1448 3 COG4713 COG4713, Predicted membrane protein Function unknown 76786730 Common - polar amino acid uptake (PAAT) family ABC transporter, permease protein SAK_0841 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 76787742 Common - nickel/cobalt uptake transporter (NiCoT) family ABC transporter, permease protein SAK_1646 67 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 76787010 Common - RelE/ParE family protein SAK_0288 2 None None None 76787423 Common - beta-lactamase, putative SAK_1737 99 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 76788463 Common - hypothetical protein SAK_0859 12 COG3091 SprT, Uncharacterized protein conserved in bacteria Function unknown 76787598 Common pbp2A penicillin-binding protein 2A SAK_2005 205 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 76787892 Common - hypothetical protein SAK_2007 5 COG4640 COG4640, Predicted membrane protein Function unknown 76788167 Common - hypothetical protein SAK_0273 27 COG3688 COG3688, Predicted RNA-binding protein containing a PIN domain General function prediction only 76788358 Common eno phosphopyruvate hydratase SAK_0713 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 76788630 Common fbp fructose-1,6-bisphosphatase SAK_0666 18 COG3855 Fbp, Uncharacterized protein conserved in bacteria Carbohydrate transport and metabolism 76788392 Common - phosphate regulon transcriptinal regulatory protein PhoB, putative SAK_1922 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 76788382 Common rbsC ribose ABC transporter, permease protein SAK_0167 151 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 76787511 Common ciaR DNA-binding response regulator CiaR SAK_1080 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 76787971 Common - OxaA-like protein precursor SAK_1623 163 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 76787995 Common - CsbD family protein SAK_0704 11 None None None 76787769 Pathogen - hypothetical protein SAK_0726 1 None None None 76788171 Common - glycosyl transferase, family 8 SAK_1489 29 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 76788160 Common - peptidase propeptide and YPEB domain protein SAK_0840 2 COG3212 COG3212, Predicted membrane protein Function unknown 76788075 Common clpC ATP-dependent Clp protease, ATP-binding subunit ClpC SAK_1848 219 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 76788675 Pathogen - hypothetical protein SAK_1709 1 None None None 76787465 Common hylB hyaluronate lyase SAK_1284 12 None None None 76787241 Pathogen - hypothetical protein SAK_1375 1 None None None 76787472 Common atpH F0F1 ATP synthase subunit delta SAK_0983 119 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 76788419 Common - hypothetical protein SAK_0621 6 None None None 76787657 Common - hypothetical protein SAK_1468 20 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 76787983 Common - ribosomal large subunit pseudouridine synthase, RluA family SAK_1178 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 76788573 Common pfoR pfoR protein SAK_1839 17 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 76786884 Pathogen - hypothetical protein SAK_0631 1 None None None 76786927 Common - bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon SAK_0675 146 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 76788452 Common - hypothetical protein SAK_1312 9 None None None 76787222 Common smc chromosome segregation protein SMC SAK_0850 220 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 76788248 Common - IS1381 transposase protein B SAK_2001 5 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 76787274 Common - HIT family protein SAK_0444 236 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 76788193 Common - site-specific recombinase, phage integrase family SAK_1943 69 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 76786760 Common pyrH uridylate kinase SAK_1537 231 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 76786995 Common - oligopeptide ABC transporter, permease protein OppC, putative SAK_0208 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 76786986 Common - sensor histidine kinase CsrS, putative SAK_1638 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76788445 Common - ABC transporter, ATP-binding protein SAK_1099 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 76788214 Common - hypothetical protein SAK_1095 27 COG4487 COG4487, Uncharacterized protein conserved in bacteria Function unknown 76787459 Pathogen - hypothetical protein SAK_0291 1 None None None 76786815 Common hup DNA-binding protein HU SAK_0606 203 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 76788001 Pathogen - acetyltransferase, GNAT family SAK_1065 3 None None None 76787139 Common - hypothetical protein SAK_0365 2 None None None 76787527 Common cspA cell surface serine endopeptidase CspA SAK_1991 78 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 76787013 Common dnaN DNA polymerase III subunit beta SAK_0002 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 76787819 Common ftsH cell division protein FtsH SAK_0015 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 76787187 Common - hypothetical protein SAK_0572 9 COG4483 COG4483, Uncharacterized protein conserved in bacteria Function unknown 76787640 Common - hypothetical protein SAK_1708 8 COG4495 COG4495, Uncharacterized protein conserved in bacteria Function unknown 76788110 Common - ferredoxin, putative SAK_1420 4 COG1141 Fer, Ferredoxin Energy production and conversion 76786966 Common - ABC transporter, ATP binding protein SAK_1517 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 76787132 Common rpoC DNA-directed RNA polymerase subunit beta' SAK_0224 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 76786722 Common secA preprotein translocase subunit SecA SAK_1699 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 76788513 Common - PTS system, putative, lactose/cellobiose family IIC component SAK_1579 31 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 76788606 Common nrdF ribonucleotide-diphosphate reductase subunit beta SAK_0942 150 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 76787993 Common dnaK molecular chaperone DnaK SAK_0147 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 76788162 Common relA GTP pyrophosphokinase SAK_1900 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 161486745 Common - ribosome-associated GTPase SAK_1799 163 COG1162 COG1162, Predicted GTPases General function prediction only 76786791 Common pepX x-prolyl-dipeptidyl aminopeptidase SAK_1744 12 COG2936 COG2936, Predicted acyl esterases General function prediction only 76786871 Common - RmuC domain protein SAK_1796 129 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 76786829 Common rpsA 30S ribosomal protein S1 SAK_1237 227 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 76786937 Common - hypothetical protein SAK_1766 37 COG2320 GrpB, Uncharacterized conserved protein Function unknown 76788688 Common - hypothetical protein SAK_0394 230 COG1098 VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) Translation, ribosomal structure and biogenesis 76787525 Common ulaA ascorbate-specific PTS system enzyme IIC SAK_1835 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 76787721 Pathogen - hypothetical protein SAK_0640 1 None None None 76788074 Common - hypothetical protein SAK_0697 2 None None None 76787435 Common cydB cytochrome d ubiquinol oxidase, subunit II SAK_1749 154 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 76786771 Pathogen - hypothetical protein SAK_1942 1 None None None 76787437 Common glgA glycogen synthase SAK_0979 139 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 76788511 Common - alkaline shock protein 23, putative SAK_1221 35 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 76787709 Common ftsK DNA translocase FtsK SAK_1552 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 76788316 Common arcC carbamate kinase SAK_2125 65 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 76787782 Common - hypothetical protein SAK_1321 5 None None None 76788323 Common - hypothetical protein SAK_1218 19 COG4912 COG4912, Predicted DNA alkylation repair enzyme DNA replication, recombination, and repair 76787890 Common accB acetyl-CoA carboxylase biotin carboxyl carrier protein subunit SAK_0424 193 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 76788407 Common - 3-hydroxybutyryl-CoA dehydrogenase SAK_1685 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 76787899 Common - sensor histidine kinase SAK_0248 103 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 76787306 Common radA DNA repair protein RadA SAK_0161 205 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 76787922 Common - hypothetical protein SAK_1120 4 None None None 76788400 Common - fructose-6-phosphate aldolase SAK_0402 105 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 76787877 Common rbsK ribokinase SAK_0170 187 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 76788467 Common - hypothetical protein SAK_0271 38 COG1939 COG1939, Uncharacterized protein conserved in bacteria Function unknown 76787333 Common - oxidoreductase, Gfo/Idh/MocA family SAK_0549 164 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 76787374 Common - hypothetical protein SAK_2085 2 None None None 76788117 Common - transcriptional regulator, putative SAK_1864 125 COG1609 PurR, Transcriptional regulators Transcription 76788011 Common - hypothetical protein SAK_1559 2 None None None 76786782 Pathogen cylJ CylJ protein SAK_0800 1 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 76788095 Common - polysaccharide deacetylase family protein SAK_0948 118 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 76787309 Common - hypothetical protein SAK_0869 11 COG4443 COG4443, Uncharacterized protein conserved in bacteria Function unknown 76787684 Common - ISSag7, transposase orfA SAK_1316 5 None None None 76788296 Common - sortase family protein SAK_1439 21 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 76786889 Common - oxidoreductase, Gfo/Idh/MocA family SAK_2023 80 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 76788620 Common infA translation initiation factor IF-1 SAK_0113 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 76788346 Common - hypothetical protein SAK_1331 2 None None None 76788484 Common - PTS system, IIC component, lactose/cellobiose family SAK_0400 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 76786941 Common cylZ cylZ protein SAK_0794 186 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 76788308 Common - hypothetical protein SAK_1807 4 None None None 76788022 Common rpoB DNA-directed RNA polymerase subunit beta SAK_0223 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 76788507 Common - peptidase, U32 (collagenase) family SAK_0867 111 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 76787668 Common - IS1381 transposase protein B SAK_1061 5 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 76787265 Common rnr ribonuclease R SAK_1512 192 COG0557 VacB, Exoribonuclease R Transcription 76787391 Common potD spermidine/putrescine ABC transporter, spermidine/putrescine-binding protein SAK_1193 137 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 76788339 Common - acetoin dehydrogenase, TPP-dependent, E1 component, alpha subunit, putative SAK_1001 154 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 76788227 Common recG ATP-dependent DNA helicase RecG SAK_1694 221 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 76786852 Common groEL chaperonin GroEL SAK_2013 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 76787941 Common - hypothetical protein SAK_1235 4 None None None 76787368 Common parC DNA topoisomerase IV subunit A SAK_1242 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 76786954 Common fhuC ferrichrome ABC transporter, ATP-binding protein SAK_1425 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 76787041 Common - helicase, RecD/TraA family SAK_1732 136 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 76786741 Common licD2 licD2 protein SAK_1453 15 COG3475 COG3475, LPS biosynthesis protein Cell envelope biogenesis, outer membrane 76786718 Common - PTS system, fructose-specific IIABC component SAK_1377 143 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 76787079 Common clpL ATP-dependent Clp protease, ATP-binding subunit ClpL SAK_1336 239 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 76786778 Common - hypothetical protein SAK_0290 8 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 76787058 Pathogen - hypothetical protein SAK_0289 1 None None None 76787267 Pathogen - hypothetical protein SAK_0861 1 None None None 76787165 Common - phosphoribosylformylglycinamidine synthase SAK_0058 233 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 76787808 Common lepB signal peptidase I SAK_1443 71 COG2932 COG2932, Predicted transcriptional regulator Transcription 76787561 Common - PTS system, galactitol-specific IIB component, putative SAK_0525 15 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 76787934 Common cadD cadmium resistance protein CadD SAK_2051 20 COG4300 CadD, Predicted permease, cadmium resistance protein Inorganic ion transport and metabolism 76787147 Common - hypothetical protein SAK_0548 4 None None None 76787403 Common - polar amino acid uptake (PAAT) family ABC transporter, ATP-binding protein SAK_0593 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 76788094 Common - nicotinate phosphoribosyltransferase SAK_0367 113 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 76787810 Pathogen - hypothetical protein SAK_0641 1 None None None 76787020 Common rpsD 30S ribosomal protein S4 SAK_2095 249 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 76787905 Common - NOL1/NOP2/sun family putative RNA methylase SAK_1088 207 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 76787639 Common - conserved hypothetical protein TIGR00247 SAK_1628 187 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 76787836 Common gltX glutamyl-tRNA synthetase SAK_0165 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 76787858 Common - YggT family protein SAK_0584 4 None None None 76788023 Common - conserved hypothetical protein TIGR01618 SAK_0616 4 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 76788557 Common - acetyltransferase, GNAT family SAK_1629 14 COG0456 RimI, Acetyltransferases General function prediction only 76788221 Common - hypothetical protein SAK_0751 5 None None None 76787631 Common ispE 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase SAK_0216 204 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 76787698 Common - DNA-binding protein SAK_1977 16 COG1396 HipB, Predicted transcriptional regulators Transcription 76788106 Common - NIF3 family protein SAK_1289 147 COG0327 COG0327, Uncharacterized conserved protein Function unknown 76788428 Common - hypothetical protein SAK_1729 3 None None None 76787288 Common - hypothetical protein SAK_1224 4 COG5547 COG5547, Small integral membrane protein Function unknown 76788195 Common - ABC transporter, ATP-binding/permease protein SAK_1156 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 76787553 Common ackA acetate kinase SAK_0234 162 COG0282 ackA, Acetate kinase Energy production and conversion 76788579 Common - hydrolase, NUDIX family SAK_0711 18 COG1443 Idi, Isopentenyldiphosphate isomerase Lipid metabolism 76787507 Common - methylated-DNA--protein-cysteine S-methyltransferase, putative SAK_1583 216 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 76787157 Common - replication initiation and membrane attachment protein, putative SAK_1636 15 COG3611 DnaB, Replication initiation/membrane attachment protein DNA replication, recombination, and repair 76787110 Common rplP 50S ribosomal protein L16 SAK_0098 218 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 76788267 Common - transcriptional regulator, Fur family SAK_0465 153 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 76787870 Common ddl D-alanyl-alanine synthetase A SAK_0892 218 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 76787551 Common - ISSag8, transposase SAK_1877 56 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 76787456 Common - cysteine synthase/cystathionine beta-synthase family protein SAK_0404 225 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 76788537 Common - sortase family protein, putative SAK_1437 5 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 76787317 Common - transcriptional antiterminator, BglG family SAK_0914 29 COG3711 BglG, Transcriptional antiterminator Transcription 76788056 Common - DNA-binding response regulator, LuxR family SAK_0392 217 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 76788148 Common sufS cysteine desulfurase SufS SAK_0201 238 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 76787051 Common - hypothetical protein SAK_1940 5 None None None 76786841 Common prmA ribosomal protein L11 methyltransferase SAK_1930 180 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 76787298 Common - glyoxalase family protein SAK_1311 51 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 76788431 Common coaD phosphopantetheine adenylyltransferase SAK_0555 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 76787070 Common pepF oligoendopeptidase F SAK_0884 84 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 76787796 Common - DNA-binding protein SAK_1724 19 COG1476 COG1476, Predicted transcriptional regulators Transcription 76786859 Common - alcohol dehydrogenase SAK_0087 213 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 76787575 Common - glycosyl transferase, group 2 family protein SAK_1449 66 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 76788383 Common - hypothetical protein SAK_0353 3 None None None 76787691 Common - peptidyl-prolyl cis-trans isomerase, cyclophilin-type SAK_1553 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 76787771 Common - oxidoreductase, short-chain dehydrogenase/reductase family SAK_1295 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 76787973 Common - transcriptional regulator, MarR family SAK_1868 128 COG1846 MarR, Transcriptional regulators Transcription 76787027 Common - hypothetical protein SAK_1421 1 None None None