Natronomonas pharaonis DSM 2160, complete genome NC_007426 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 76802728 Common suhB probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase , archaeal type NP4188A 167 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 76801346 Nonpathogen - hypothetical protein NP1390A 3 None None None 76802250 Common - glycerol-3-phosphate cytidyltransferase homolog NP3220A 116 COG0615 TagD, Cytidylyltransferase Cell envelope biogenesis, outer membrane / Lipid metabolism 76801284 Nonpathogen - hypothetical protein NP1264A 25 COG2433 COG2433, Uncharacterized conserved protein Function unknown 76800734 Nonpathogen - transmembrane protein (homolog 4 to type II secretion system proteins TadC) NP0158A 4 COG1955 FlaJ, Archaeal flagella assembly protein J Cell motility and secretion / Intracellular trafficking and secretion 76801401 Common abc31p_1 ABC-type transport system permease protein (probable Fe-S cluster assembly protein) 1 NP1502A 185 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 76803184 Common - homolog to RNA-binding protein regulatory subunit/ protease NP5112A 143 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 76802423 Common - hypothetical protein NP3570A 7 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 76802838 Common aspC_3 aspartate aminotransferase NP4410A 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 76802575 Common - hypothetical protein NP3880A 88 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 76802211 Common - predicted lipoprotein NP3142A 6 COG4314 NosL, Predicted lipoprotein involved in nitrous oxide reduction Energy production and conversion 76803068 Nonpathogen rpl24p 50S ribosomal protein L24P NP4876A 34 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 76803230 Common - predicted ATPase (homolog 4 to type II/IV secretion system proteins TadA/VirB11) NP5204A 70 COG0630 VirB11, Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis Cell motility and secretion / Intracellular trafficking and secretion 76801876 Nonpathogen - probable transcription regulator NP2466A 3 COG1309 AcrR, Transcriptional regulator Transcription 76802812 Common sucC succinate--CoA ligase (ADP-forming) , beta subunit NP4356A 211 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 76802447 Nonpathogen - homolog 1 to S-adenosylmethionine-dependent methyltransferase 3 NP3618A 18 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 76801265 Common mcmA_2 methylmalonyl-CoA mutase , subunit A 2 NP1226A 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 76802692 Nonpathogen - hypothetical protein NP4116A 6 None None None 76801378 Common aatC aspartyl-tRNA(Asn) amidotransferase subunit C NP1454A 132 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 76802966 Common ugd_1 UDP-glucose 6-dehydrogenase 1 NP4668A 206 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 76801817 Nonpathogen - hypothetical protein NP2348A 1 None None None 76803262 Nonpathogen - hypothetical protein NP5270A 2 None None None 76801643 Common abc10a1 ABC-type transport system ATP-binding protein I (probable substrates urea/short chain-amides) NP1996A 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 76802721 Common lfl acyl-CoA synthetase IV (probable long-chain-fatty-acid--CoA ligase ) NP4174A 214 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 76800720 Common tef2 elongation factor EF-2 NP0130A 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 76802091 Nonpathogen - hypothetical protein NP2898A 1 None None None 76803103 Common fdhB_1 conserved anaerobic dehydrogenase subunit/ anaerobic dehydrogenase (probable formate dehydrogenase , dimethyl sulfoxide reductase ), iron-sulfur binding subunit 1 NP4946A 163 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 76801937 Common ushA_2 5'-nucleotidase 2; 2',3'-cyclic-nucleotide 2'-phosphodiesterase 2; UDP-sugar hydrolase 2 NP2590A 129 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 76801930 Nonpathogen - hypothetical protein NP2576A 3 COG3360 COG3360, Uncharacterized conserved protein Function unknown 76803235 Nonpathogen - hypothetical protein NP5214A 3 None None None 76801248 Common metG methionyl-tRNA synthetase NP1192A 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 76802076 Common - hypothetical protein NP2868A 66 COG2606 EbsC, Uncharacterized conserved protein Function unknown 76801053 Common trpE_2 anthranilate synthase , component I 2 NP0802A 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 76802245 Nonpathogen rps3aR 30S ribosomal protein S3Ae NP3210A 34 COG1890 RPS1A, Ribosomal protein S3AE Translation, ribosomal structure and biogenesis 76802670 Common cna probable rRNA methylase NP4072A 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 76802331 Common alkK_4 acyl-CoA synthetase II 4 (probable long-chain-fatty-acid--CoA ligase ) NP3386A 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 76802700 Common abc05p1 ABC-type transport system permease protein (probable substrates branched-chain/neutral amino acids) I 1 NP4132A 136 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 76801437 Common - hypothetical protein NP1574A 14 COG4923 COG4923, Uncharacterized conserved protein Function unknown 76802633 Common - AAA-type ATPase (transitional ATPase homolog) NP3998A 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 76800704 Nonpathogen - hypothetical protein NP0098A 6 None None None 76802418 Common tp13 major facilitator family transporter 3 (probable oxalate/formate antiporter; probable sugar transporter) NP3560A 100 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 76800697 Common - uracil-DNA glycosylase homolog NP0084A 152 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 76800823 Nonpathogen - hypothetical protein NP0338A 7 COG1645 COG1645, Uncharacterized Zn-finger containing protein General function prediction only 76801081 Common - lipase/ esterase NP0858A 119 COG0657 Aes, Esterase/lipase Lipid metabolism 76801103 Nonpathogen - homolog to thiamine biosynthesis protein ThiS (probable sulfur donor) NP0902A 3 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 76802851 Nonpathogen - predicted DNA binding protein NP4436A 11 COG3413 COG3413, Predicted DNA binding protein General function prediction only 76801999 Common - homolog to hydrolase NP2714A 34 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 76801779 Common pyrH uridylate kinase NP2272A 56 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 76801270 Nonpathogen - hypothetical protein NP1236A 5 None None None 76802858 Nonpathogen rplP0 acidic ribosomal protein P0 NP4450A 33 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 76802477 Nonpathogen rpoF DNA-directed RNA polymerase subunit F NP3682A 23 COG1460 COG1460, Uncharacterized protein conserved in archaea Function unknown 76802270 Nonpathogen - hypothetical protein NP3262A 4 COG5551 COG5551, Uncharacterized conserved protein Function unknown 76801449 Common nirK nitrite reductase , copper-containing NP1598A 79 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 76801049 Common guaAa_2 homolog 1 to GMP synthase (glutamine-hydrolyzing) , subunit A NP0794A 225 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 76801317 Common gpmB probable fructose-2,6-bisphosphatase ; probable phosphoglyceromutase , type 2 NP1332A 188 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 76802885 Common cbs_1 CBS domain protein 1 NP4504A 90 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 76802709 Common alkK_5 acyl-CoA synthetase II 5 (probable long-chain-fatty-acid--CoA ligase ) NP4150A 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 76801417 Common - pterin operon protein NP1534A 4 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 76801823 Nonpathogen - hypothetical protein NP2360A 1 None None None 76800798 Common gnd 6-phosphogluconate dehydrogenase-like protein NP0286A 148 COG1023 Gnd, Predicted 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 76802032 Common - hypothetical protein NP2780A 39 COG3428 COG3428, Predicted membrane protein Function unknown 76801533 Nonpathogen rps14_2 ribosomal protein S14.2 NP1768A 16 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 76801320 Nonpathogen - hypothetical protein NP1338A 3 None None None 76801772 Common hisB imidazoleglycerol-phosphate dehydratase NP2258A 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 76801843 Nonpathogen - hypothetical protein NP2400A 19 COG1920 COG1920, Uncharacterized conserved protein Function unknown 76801464 Nonpathogen - hypothetical protein NP1628A 22 COG1497 COG1497, Predicted transcriptional regulator Transcription 76800838 Common mvaA_2 hydroxymethylglutaryl-CoA reductase (NADPH) 1 NP0368A 49 COG1257 HMG1, Hydroxymethylglutaryl-CoA reductase Lipid metabolism 76801074 Nonpathogen - predicted archaeal sugar kinase NP0844A 31 COG1829 COG1829, Predicted archaeal kinase (sugar kinase superfamily) General function prediction only 76801494 Nonpathogen - hypothetical protein NP1690A 5 COG1378 COG1378, Predicted transcriptional regulators Transcription 76803309 Nonpathogen - hypothetical protein NP5364A 3 COG5045 COG5045, Ribosomal protein S10E Translation, ribosomal structure and biogenesis 76801561 Common - probable stress response protein NP1826A 156 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 76801948 Common acaB_2 acetyl-CoA C-acyltransferase 2 NP2612A 186 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 76801406 Nonpathogen - hypothetical protein NP1512A 1 None None None 76801239 Common pncB nicotinate phosphoribosyltransferase NP1174A 115 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 76801175 Common - probable transcription regulator NP1048A 58 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 76800883 Common - hypothetical protein NP0462A 58 COG0622 COG0622, Predicted phosphoesterase General function prediction only 76802128 Nonpathogen - hypothetical protein NP2974A 2 None None None 76801473 Common lysA diaminopimelate decarboxylase NP1646A 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 76802150 Nonpathogen - hypothetical protein NP3018A 1 None None None 76800896 Common fadB_5 probable enoyl-CoA hydratase II 5 NP0488A 63 COG2030 MaoC, Acyl dehydratase Lipid metabolism 76801158 Nonpathogen rpl31R 50S ribosomal protein L31e NP1014A 27 COG2097 RPL31A, Ribosomal protein L31E Translation, ribosomal structure and biogenesis 76802768 Nonpathogen sdhD succinate dehydrogenase , subunit D (membrane anchor protein) NP4268A 5 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 76802881 Common - repair DNA N-glycosylase / DNA-(apurinic or apyrimidinic site) lyase NP4496A 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 76802956 Nonpathogen - hypothetical protein NP4648A 1 None None None 76801444 Nonpathogen - hypothetical protein NP1588A 20 COG2138 COG2138, Uncharacterized conserved protein Function unknown 76800997 Common - probable stress response protein NP0690A 57 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 76802453 Nonpathogen - hypothetical protein NP3630A 3 None None None 76802657 Common porA pyruvate--ferredoxin oxidoreductase , alpha subunit NP4046A 109 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 76801584 Nonpathogen - hypothetical protein NP1872A 13 COG4083 COG4083, Predicted membrane protein Function unknown 76801808 Nonpathogen - hypothetical protein NP2330A 1 None None None 76801926 Nonpathogen - hypothetical protein NP2568A 4 None None None 76802940 Nonpathogen - hypothetical protein NP4614A 4 None None None 76801923 Common hcpE_3 probable 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase 3; probable 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase 3 NP2562A 177 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 76802353 Common abc08a2 ABC-type transport system ATP-binding protein II (probable substrates branched-chain/neutral amino acids) 4 NP3430A 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 76801504 Nonpathogen - homolog to stress response protein NP1710A 11 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 76802801 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase NP4334A 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 76802653 Nonpathogen - hypothetical protein NP4038A 2 COG5373 COG5373, Predicted membrane protein Function unknown 76803029 Nonpathogen rps8R 30S ribosomal protein S8e NP4798A 34 COG2007 RPS8A, Ribosomal protein S8E Translation, ribosomal structure and biogenesis 76802314 Nonpathogen - hypothetical protein NP3352A 4 None None None 76802961 Common gtl_1 glycosyltransferase 1 (probable dolichyl-phosphate beta-D-mannosyltransferase ) NP4658A 147 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 76801617 Common - ISH4-type transposase NP1938A 30 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 76802056 Common rps13p 30S ribosomal protein S13P NP2828A 221 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 76802515 Nonpathogen - hypothetical protein NP3760A 3 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 76800754 Common - predicted ATPase NP0198A 68 COG1855 COG1855, ATPase (PilT family) General function prediction only 76802395 Common pmm_3 phosphohexomutase 3 (phosphoglucomutase , phosphomannomutase ) NP3514A 239 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 76800954 Common idsA_2 probable multifunctional long-chain (E)-prenyl diphosphate synthase NP0604A 227 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 76801863 Common abc28p ABC-type transport system permease protein NP2440A 17 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 76803125 Common pgi glucose-6-phosphate isomerase NP4992A 210 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 76802530 Common - homolog 2 to S-adenosylmethionine-dependent methyltransferase 3 NP3790A 61 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 76801571 Common - GAF domain protein NP1846A 70 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 76803013 Common ubiA prenyltransferase NP4766A 15 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 76802543 Common btuC corrinoid ABC transporter permease NP3816A 190 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 76801214 Common cbiT precorrin-8W decarboxylase NP1124A 87 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 76802665 Nonpathogen - hypothetical protein NP4062A 1 None None None 76802864 Nonpathogen - hypothetical protein NP4462A 3 None None None 76801641 Nonpathogen rps17E 30S ribosomal protein S17e NP1992A 33 COG1383 RPS17A, Ribosomal protein S17E Translation, ribosomal structure and biogenesis 76802994 Common - transcription regulator NP4726A 108 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 76801329 Common ribC riboflavin synthase subunit alpha NP1356A 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 76801630 Common pyrG CTP synthetase NP1968A 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 76802385 Nonpathogen - hypothetical protein NP3494A 1 None None None 76800714 Common nusA transcription elongation factor NusA-like protein NP0118A 122 COG0195 NusA, Transcription elongation factor Transcription 76801637 Common abc14p1 ABC-type transport system permease protein I (probable substrate phosphate) 1 NP1982A 226 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 76802785 Common - hypothetical protein NP4302A 25 COG5282 COG5282, Uncharacterized conserved protein Function unknown 76801742 Nonpathogen - hypothetical protein NP2196A 1 None None None 76801849 Common pspA probable stress response protein NP2412A 71 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 76802367 Common - signal-transducing histidine kinase; response regulator NP3458A 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76801672 Common folD methylenetetrahydrofolate dehydrogenase ; methenyltetrahydrofolate cyclohydrolase NP2054A 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 76802360 Common prkA_1 predicted serine protein kinase 1 NP3444A 71 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 76802982 Nonpathogen - hypothetical protein NP4700A 1 None None None 76800993 Common - response regulator NP0682A 89 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 76801201 Nonpathogen - cobalamin cluster protein NP1098A 2 COG5446 COG5446, Predicted integral membrane protein Function unknown 76801151 Common - hypothetical protein NP1000A 42 COG3651 COG3651, Uncharacterized protein conserved in bacteria Function unknown 76801799 Common nuoM NADH dehydrogenase-like complex, subunit M NP2312A 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 76802320 Nonpathogen - hypothetical protein NP3364A 4 None None None 76803198 Nonpathogen - hypothetical protein NP5140A 2 None None None 76803072 Common rps8p 30S ribosomal protein S8P NP4884A 163 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 76800683 Common - probable stress response protein NP0056A 93 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 76802685 Nonpathogen - hypothetical protein NP4102A 4 None None None 76802138 Common leuA_3 homolog to 2-isopropylmalate synthase , homocitrate synthase NP2994A 23 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 76803244 Nonpathogen rpl37aR ribosomal protein L37a.eR NP5232A 11 COG1997 RPL43A, Ribosomal protein L37AE/L43A Translation, ribosomal structure and biogenesis 76802923 Common acaB_5 acetyl-CoA C-acyltransferase 5 NP4580A 170 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 76803110 Common fdhB_2 anaerobic dehydrogenase (probable formate dehydrogenase , dimethyl sulfoxide reductase ), iron-sulfur binding subunit 2 NP4960A 160 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 76802604 Nonpathogen - hypothetical protein NP3938A 2 None None None 76800921 Common mutS_1 DNA mismatch repair protein NP0538A 201 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 76803221 Nonpathogen tfbA_8 transcription initiation factor TFB 8 NP5186A 34 COG1405 SUA7, Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB Transcription 76802458 Common abc24p ABC-type transport system permease protein (probable substrates branched-chain amino acids), azaleucine resistance protein NP3644A 98 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 76802538 Nonpathogen tp25 transporter 25 (drug/metabolite family transporter 3) NP3806A 4 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 76802774 Common - IS1341-type transposase NP4280A 19 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 76802131 Common - hypothetical protein NP2980A 44 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 76800927 Common lysC aspartate kinase NP0550A 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 76802645 Common - predicted ATPase (homolog 2 to type II/IV secretion system proteins TadA/VirB11) NP4022A 208 COG0630 VirB11, Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis Cell motility and secretion / Intracellular trafficking and secretion 76802107 Nonpathogen - hypothetical protein NP2932A 1 None None None 76802494 Nonpathogen tfbA_4 transcription initiation factor TFB 4 NP3718A 22 COG1405 SUA7, Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB Transcription 76801547 Nonpathogen - hypothetical protein NP1798A 1 None None None 76802185 Nonpathogen mtfK_2 FKBP-type peptidylprolyl isomerase 2 NP3090A 29 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 76802433 Common - IS1341-type transposase NP3590A 76 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 76803145 Common - S-adenosylmethionine-dependent methyltransferase 1 NP5034A 196 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 76802873 Nonpathogen rnp4 ribonuclease P protein component 4 NP4480A 8 COG2023 RPR2, RNase P subunit RPR2 Translation, ribosomal structure and biogenesis 76802736 Nonpathogen - hypothetical protein NP4204A 4 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 76801050 Common - homolog 2 to PPE-repeat proteins NP0796A 4 None None None 76800663 Nonpathogen - hypothetical protein NP0016A 21 COG1326 COG1326, Uncharacterized archaeal Zn-finger protein General function prediction only 76800700 Common - signal-transducing histidine kinase; probable GAF, PAS/PAC domain protein NP0090A 97 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76803179 Nonpathogen - hypothetical protein NP5102A 3 None None None 76802938 Common - hypothetical protein NP4610A 28 COG1276 PcoD, Putative copper export protein Inorganic ion transport and metabolism 76801755 Common - hypothetical protein NP2224A 60 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 76803172 Common - uracil-DNA glycosylase homolog NP5088A 127 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 76802010 Common menC O-succinylbenzoate-CoA synthase (OSB synthase; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase) NP2736A 69 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 76801574 Nonpathogen - hypothetical protein NP1852A 2 None None None 76803054 Nonpathogen - hypothetical protein NP4848A 3 COG0011 COG0011, Uncharacterized conserved protein Function unknown 76803079 Nonpathogen rpl15p 50S ribosomal protein L15P NP4898A 25 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 76802798 Nonpathogen - hypothetical protein NP4328A 3 None None None 76801832 Nonpathogen - hypothetical protein NP2378A 1 None None None 76801959 Common mch N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase NP2634A 27 COG3252 COG3252, Methenyltetrahydromethanopterin cyclohydrolase Coenzyme metabolism 76801269 Common korB 2-oxoglutarate ferredoxin oxidoreductase subunit beta NP1234A 109 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 76800812 Nonpathogen hstA archaeal histone NP0316A 4 COG2036 HHT1, Histones H3 and H4 Chromatin structure and dynamics 76801388 Common - homolog to acetyltransferase NP1474A 11 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 76801556 Common msc_2 probable mechanosensitive channel (nonfunctional, C-terminal part) NP1816A 132 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 76801168 Common - probable transcription regulator NP1034A 50 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 76802488 Common trxA_3 thioredoxin NP3704A 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 76800672 Nonpathogen - hypothetical protein NP0034A 1 None None None 76800914 Nonpathogen - hypothetical protein NP0524A 1 None None None 76802713 Common hisF imidazoleglycerol-phosphate synthase , cyclase subunit HisF NP4158A 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 76801527 Common htr22 transducer protein htr22 NP1756A 141 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 76801750 Common acaB_8 acetyl-CoA C-acyltransferase 8 NP2214A 90 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 76802831 Nonpathogen - hypothetical protein NP4394A 1 None None None 76801733 Common rtcB_1 RtcB-like protein 1 NP2178A 120 COG1690 RtcB, Uncharacterized conserved protein Function unknown 76800763 Common grpE dnaJ/dnaK ATPase stimulator grpE NP0216A 174 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 76800661 Nonpathogen gapB glyceraldehyde-3-phosphate dehydrogenase NP0012A 36 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 76802613 Common deoA thymidine phosphorylase NP3958A 121 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 76800970 Nonpathogen - hypothetical protein NP0636A 1 None None None 76800949 Common - probable GTP-binding protein NP0594A 63 COG1100 COG1100, GTPase SAR1 and related small G proteins General function prediction only 76803246 Nonpathogen - conserved rpo operon protein NP5236A 5 COG2892 COG2892, Uncharacterized protein conserved in archaea Function unknown 76803033 Common - probable stress response protein NP4806A 155 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 76801204 Nonpathogen - conserved cobalamin operon protein NP1104A 4 COG1520 COG1520, FOG: WD40-like repeat Function unknown 76801819 Nonpathogen - hypothetical protein NP2352A 1 None None None 76802944 Nonpathogen - probable cell surface glycoprotein NP4622A 3 None None None 76801423 Common cmo_1 molybdopterin-based tungsten cofactor biosynthesis protein 1 NP1546A 120 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 76801668 Nonpathogen - ccm operon protein NP2046A 1 None None None 76801281 Nonpathogen tif1A_1 translation initiation factor IF-1A NP1258A 34 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 76800982 Common degP probable periplasmic serine proteinase NP0660A 221 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 76801525 Common abc17p ABC-type transport system permease protein (probable substrate phosphonate) 1 NP1752A 83 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 76801512 Nonpathogen - hypothetical protein NP1726A 1 None None None 76802340 Nonpathogen - homolog to succinylglutamate desuccinylase NP3404A 9 COG2988 COG2988, Succinylglutamate desuccinylase Amino acid transport and metabolism 76802852 Nonpathogen - hypothetical protein NP4438A 3 None None None 76801128 Nonpathogen - hypothetical protein NP0952A 4 None None None 76802146 Nonpathogen - hypothetical protein NP3010A 8 COG4243 COG4243, Predicted membrane protein Function unknown 76802349 Common alkK_3 acyl-CoA synthetase II 3 (probable long-chain-fatty-acid--CoA ligase ) NP3422A 222 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 76802289 Nonpathogen - hypothetical protein NP3300A 1 None None None 76802593 Common abc11s ABC-type transport system substrate-binding protein (probable substrate copper) 1 NP3916A 51 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 76802829 Nonpathogen - hypothetical protein NP4390A 1 None None None 76802298 Nonpathogen - hypothetical protein NP3318A 1 None None None 76800876 Common arcB ornithine cyclodeaminase NP0448A 96 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 76802503 Nonpathogen rnp2 ribonuclease P protein component 2 NP3736A 6 COG1369 POP5, RNase P/RNase MRP subunit POP5 Translation, ribosomal structure and biogenesis 76801106 Common nadM1_1 nicotinamide-nucleotide adenylyltransferase 1 NP0908A 49 COG1056 NadR, Nicotinamide mononucleotide adenylyltransferase Coenzyme metabolism 76801002 Nonpathogen - hypothetical protein NP0700A 2 None None None 76801258 Nonpathogen - hypothetical protein NP1212A 1 None None None 76802160 Common abc22s ABC-type transport system periplasmic substrate-binding protein (probable substrates tungstate/sulfate) NP3040A 61 COG2998 TupB, ABC-type tungstate transport system, permease component Coenzyme metabolism 76801861 Common - hypothetical protein NP2436A 11 COG2322 COG2322, Predicted membrane protein Function unknown 76801953 Nonpathogen tp54_1 predicted TRAP-type transport system periplasmic protein 2 NP2622A 8 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 76801974 Common - transcription regulator NP2664A 13 COG1522 Lrp, Transcriptional regulators Transcription 76802426 Nonpathogen - hypothetical protein NP3576A 1 None None None 76802513 Nonpathogen - hypothetical protein NP3756A 3 None None None 76801430 Nonpathogen - hypothetical protein NP1560A 1 None None None 76800776 Nonpathogen - hypothetical protein NP0242A 2 None None None 76801227 Nonpathogen - hypothetical protein NP1150A 3 None None None 76801532 Common phhB pterin-4-alpha-carbinolamine dehydratase NP1766A 122 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 76801593 Common - IS1341-type transposase NP1890A 50 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 76801505 Common - protein N-acetyltransferase homolog NP1712A 28 COG3153 COG3153, Predicted acetyltransferase General function prediction only 76801787 Common - predicted lipoprotein NP2288A 10 None None None 76801967 Common glo_4 homolog 1 to lyase/ dioxygenase NP2650A 20 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 76802663 Nonpathogen - hypothetical protein NP4058A 19 COG1340 COG1340, Uncharacterized archaeal coiled-coil protein Function unknown 76802067 Common mvk mevalonate kinase NP2850A 32 COG1577 ERG12, Mevalonate kinase Lipid metabolism 76801857 Nonpathogen - hypothetical protein NP2428A 5 None None None 76800845 Common - hypothetical protein NP0382A 44 COG2102 COG2102, Predicted ATPases of PP-loop superfamily General function prediction only 76803206 Nonpathogen - homolog to chromosome partition protein NP5156A 4 None None None 76801395 Common dapA dihydrodipicolinate synthase NP1490A 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 76802957 Common - MoxR-like ATPase NP4650A 176 COG0714 COG0714, MoxR-like ATPases General function prediction only 76803233 Nonpathogen - hypothetical protein NP5210A 2 None None None 76801131 Common - hypothetical protein NP0958A 24 COG3358 COG3358, Uncharacterized conserved protein Function unknown 76801687 Nonpathogen flg_1 flagellin precursor 1 NP2086A 8 COG1681 FlaB, Archaeal flagellins Cell motility and secretion 76803042 Nonpathogen - hypothetical protein NP4824A 1 None None None 76801702 Nonpathogen - hypothetical protein NP2116A 4 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 76802846 Common ham1 Nucleoside-triphosphatase NP4426A 212 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 76803228 Nonpathogen - hypothetical protein NP5200A 2 None None None 76801777 Nonpathogen - probable metalloprotease NP2268A 23 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 76800685 Common hemAT transducer protein hemAT NP0060A 166 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 76801786 Common purK phosphoribosylaminoimidazole carboxylase , ATPase subunit NP2286A 194 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 76802263 Nonpathogen - hypothetical protein NP3246A 1 None None None 76802592 Common trx_1 thioredoxin 1 NP3914A 14 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 76801904 Common secD preprotein translocase subunit SecD NP2522A 74 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 76802992 Nonpathogen - hypothetical protein NP4722A 5 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 76801916 Nonpathogen - hypothetical protein NP2548A 1 None None None 76801496 Nonpathogen - hypothetical protein NP1694A 1 None None None 76802221 Common trpA tryptophan synthase subunit alpha NP3162A 212 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 76802286 Nonpathogen - hypothetical protein NP3294A 1 None None None 76800856 Common citB_1 aconitate hydratase NP0404A 223 COG1048 AcnA, Aconitase A Energy production and conversion 76802100 Common - DNA-directed DNA polymerase (family Y) (archaeal DNA polymerase IV) NP2918A 184 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 76800747 Nonpathogen pfdA prefoldin alpha subunit NP0184A 9 COG1730 GIM5, Predicted prefoldin, molecular chaperone implicated in de novo protein folding Posttranslational modification, protein turnover, chaperones 76802836 Nonpathogen - GAF domain protein; predicted DNA binding protein NP4406A 26 COG3413 COG3413, Predicted DNA binding protein General function prediction only 76800659 Common - homolog 2 to lysine biosynthesis regulator/ribosomal protein S6 modification enzyme (glutaminyl transferase) NP0008A 99 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 76801006 Nonpathogen - hypothetical protein NP0708A 3 None None None 76801847 Common - hypothetical protein NP2408A 10 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 76801479 Nonpathogen - hypothetical protein NP1660A 1 None None None 76802062 Common rps9p 30S ribosomal protein S9P NP2840A 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 76801803 Common mcmA_1 methylmalonyl-CoA mutase , subunit A 1 NP2320A 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 76801722 Nonpathogen flaH fla cluster protein FlaH NP2156A 25 COG2874 FlaH, Predicted ATPases involved in biogenesis of archaeal flagella Cell motility and secretion / Intracellular trafficking and secretion 76802808 Nonpathogen tatA_1 sec-independent protein translocase component TatA 1 NP4348A 4 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 76800805 Common hom homoserine dehydrogenase NP0302A 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 76803272 Nonpathogen - hypothetical protein NP5290A 1 None None None 76802193 Common - predicted ATPase (homolog 1 to type II/IV secretion system proteins TadA/VirB11) NP3106A 228 COG0630 VirB11, Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis Cell motility and secretion / Intracellular trafficking and secretion 76803216 Nonpathogen - hypothetical protein NP5176A 3 None None None 76801693 Nonpathogen flaG_2 fla cluster protein FlaG 2 NP2098A 4 COG3354 FlaG, Putative archaeal flagellar protein G Cell motility and secretion 76803062 Nonpathogen rpl22p 50S ribosomal protein L22P NP4864A 34 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 76802668 Common - hypothetical protein NP4068A 17 COG4186 COG4186, Predicted phosphoesterase or phosphohydrolase General function prediction only 76803069 Nonpathogen rps4R 30S ribosomal protein S4e NP4878A 34 COG1471 RPS4A, Ribosomal protein S4E Translation, ribosomal structure and biogenesis 76800679 Common msrB peptide methionine sulfoxide reductase (R-form specific) NP0048A 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 76803196 Common - predicted transporter NP5136A 166 COG4147 DhlC, Predicted symporter General function prediction only 76801796 Nonpathogen nuoJ2 NADH dehydrogenase-like complex, subunit J2 NP2306A 1 None None None 76802088 Common htr29 transducer protein htr28 NP2892A 129 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 76800932 Common oxdhA_1 2-oxoacid dehydrogenase E1 component, alpha subunit 1 NP0560A 154 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 76800942 Nonpathogen - hypothetical protein NP0580A 10 COG2968 COG2968, Uncharacterized conserved protein Function unknown 76802826 Common cpx cytochrome-c peroxidase (CytC-type peroxidase) NP4384A 94 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 76802999 Nonpathogen - hypothetical protein NP4736A 1 None None None 76801195 Common uvrC excinuclease ABC chain C NP1086A 224 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 76801986 Nonpathogen - hypothetical protein NP2688A 1 None None None 76801814 Nonpathogen - hypothetical protein NP2342A 2 None None None 76802339 Common - hypothetical protein NP3402A 85 COG2128 COG2128, Uncharacterized conserved protein Function unknown 76803155 Common - IS1341-type transposase NP5054A 70 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 76803020 Nonpathogen - hypothetical protein NP4780A 26 COG1831 COG1831, Predicted metal-dependent hydrolase (urease superfamily) General function prediction only 76801034 Common abc01a_1 ABC-type transport system ATP-binding protein (probable substrates dipeptide/oligopeptide/nickel) I 1 NP0764A 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 76803095 Common - hypothetical protein NP4930A 33 COG1907 COG1907, Predicted archaeal sugar kinases General function prediction only 76802121 Nonpathogen cbaC CbaC protein NP2960A 1 None None None 76802057 Common rps4p 30S ribosomal protein S4 NP2830A 116 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 76802555 Nonpathogen - hypothetical protein NP3840A 1 None None None 76801308 Common citZ citrate (si)-synthase NP1314A 194 COG0372 GltA, Citrate synthase Energy production and conversion 76801567 Nonpathogen - probable transcription regulator NP1838A 3 COG1777 COG1777, Predicted transcriptional regulators Transcription 76802021 Common fadB_2 enoyl-CoA hydratase II 2 NP2758A 102 COG2030 MaoC, Acyl dehydratase Lipid metabolism 76803295 Nonpathogen - hypothetical protein NP5336A 1 None None None 76801625 Nonpathogen - hypothetical protein NP1958A 1 None None None 76801830 Nonpathogen - hypothetical protein NP2374A 1 None None None 76801717 Nonpathogen - hypothetical protein NP2146A 30 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 76801178 Common - F420-0--gamma-glutamyl ligase NP1054A 44 COG1478 COG1478, Uncharacterized conserved protein Function unknown 76802745 Common mutY A/G-specific adenine glycosylase NP4222A 213 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 76800874 Nonpathogen endA tRNA splicing endonuclease NP0444A 33 COG1676 SEN2, tRNA splicing endonuclease Translation, ribosomal structure and biogenesis 76800829 Nonpathogen - hypothetical protein NP0350A 1 None None None 76803109 Nonpathogen - anaerobic dehydrogenase transmembrane subunit NP4958A 1 COG3301 NrfD, Formate-dependent nitrite reductase, membrane component Inorganic ion transport and metabolism 76802747 Common narB_1 nitrate reductase 1, catalytic subunit NP4226A 193 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 76801141 Common - homolog 3 to thiosulfate sulfurtransferase / hydrolase (probable hydroxyacylglutathione hydrolase ) 1 NP0980A 186 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 76801868 Common coxC cytochrome-c-like terminal oxidase , subunit III NP2450A 146 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 76801517 Nonpathogen - hypothetical protein NP1736A 2 None None None 76801939 Common - hypothetical protein NP2594A 67 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 76801090 Nonpathogen - hypothetical protein NP0876A 2 None None None 76801326 Common tatC_2 sec-independent protein translocase component TatC 2 NP1350A 189 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 76802525 Common bolA probable BolA-like protein NP3780A 64 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 76803134 Common - hypothetical protein NP5012A 29 COG1244 COG1244, Predicted Fe-S oxidoreductase General function prediction only 76801197 Common cbiC precorrin-8X methylmutase NP1090A 113 COG2082 CobH, Precorrin isomerase Coenzyme metabolism 76803167 Nonpathogen rpoE2 DNA-directed RNA polymerase subunit E'' NP5078A 32 COG2093 COG2093, DNA-directed RNA polymerase, subunit E'' Transcription 76801310 Nonpathogen - hypothetical protein NP1318A 33 COG1571 COG1571, Predicted DNA-binding protein containing a Zn-ribbon domain General function prediction only 76800918 Common trpD_2 homolog to anthranilate phosphoribosyltransferase NP0532A 211 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 76802376 Common - conserved topoisomerase cluster protein NP3476A 33 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 76801018 Nonpathogen purO IMP cyclohydrolase NP0732A 13 COG3363 COG3363, Archaeal IMP cyclohydrolase Nucleotide transport and metabolism 76801163 Nonpathogen atpE V-type ATP synthase subunit E NP1024A 14 COG1390 NtpE, Archaeal/vacuolar-type H+-ATPase subunit E Energy production and conversion 76801062 Nonpathogen - hypothetical protein NP0820A 3 None None None 76801603 Nonpathogen - hypothetical protein NP1910A 5 None None None 76801878 Common - transcription regulator NP2470A 9 COG1522 Lrp, Transcriptional regulators Transcription 76802175 Common - probable N-acetyltransferase NP3070A 96 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 76800699 Nonpathogen - hypothetical protein NP0088A 4 None None None 76801466 Common thrC_3 threonine synthase 3 NP1632A 112 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 76802629 Nonpathogen priA DNA primase small subunit NP3990A 32 COG1467 PRI1, Eukaryotic-type DNA primase, catalytic (small) subunit DNA replication, recombination, and repair 76802105 Common guaAa_4 homolog 3 to GMP synthase (glutamine-hydrolyzing) , subunit A NP2928A 194 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 76800781 Common - probable transcription regulator NP0252A 63 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 76801661 Common guaD_2 probable nucleoside deaminase 2 (cytosine deaminase , guanine deaminase ) NP2032A 73 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 76801932 Nonpathogen - hypothetical protein NP2580A 3 None None None 76801291 Nonpathogen - hypothetical protein NP1280A 15 COG3390 COG3390, Uncharacterized protein conserved in archaea Function unknown 76801099 Nonpathogen - hypothetical protein NP0894A 1 None None None 76802755 Common acs_2 acyl-CoA synthetase I 2 NP4242A 222 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 76801076 Nonpathogen - hypothetical protein NP0848A 30 COG1701 COG1701, Uncharacterized protein conserved in archaea Function unknown 76802908 Common uppS_1 di-trans,poly-cis-decaprenylcistransferase 1; (Z)-prenyl diphosphate synthase 1 NP4550A 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 76801315 Common hemX uroporphyrin-III C-methyltransferase NP1328A 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 76803286 Nonpathogen hsp20_4 hsp20-type chaperone NP5318A 4 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 76801358 Common - hypothetical protein NP1414A 221 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 76801470 Common - signal-transducing histidine kinase; probable PAS/PAC domain protein NP1640A 32 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76802196 Common - probable restriction/modification enzyme NP3112A 63 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 76802232 Common suk sugar kinase (probable ketohexokinase , fructokinase , ribokinase , 2-dehydro-3-deoxygluconokinase ) NP3184A 32 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 76801334 Common - predicted cell surface protein/ lipoprotein NP1366A 115 COG1520 COG1520, FOG: WD40-like repeat Function unknown 76803256 Common argX probable arginine biosynthesis regulator (lysine biosynthesis regulator lysX homolog) NP5258A 112 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 76801740 Common leuD 3-isopropylmalate dehydratase , small subunit NP2192A 209 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 76802508 Common moaC putative molybdenum cofactor biosynthesis protein C NP3746A 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 76801524 Common abc17a ABC-type transport system ATP-binding protein (probable substrate phosphonate) 1 NP1750A 249 COG3638 COG3638, ABC-type phosphate/phosphonate transport system, ATPase component Inorganic ion transport and metabolism 76801997 Common mcmB methylmalonyl-CoA mutase , subunit B (cobalamin-binding subunit) NP2710A 112 COG2185 Sbm, Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding) Lipid metabolism 76801928 Common - hypothetical protein NP2572A 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 76801610 Nonpathogen - sugar metabolism cluster protein NP1924A 1 None None None 76801535 Common mdh_2 malic enzyme NP1772A 214 COG0281 SfcA, Malic enzyme Energy production and conversion 76802309 Common trpE_1 anthranilate synthase component I NP3342A 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 76801854 Common mvaA_1 hydroxymethylglutaryl-CoA reductase (NADPH) 1 NP2422A 39 COG1257 HMG1, Hydroxymethylglutaryl-CoA reductase Lipid metabolism 76802651 Nonpathogen - hypothetical protein NP4034A 4 COG4028 COG4028, Predicted P-loop ATPase/GTPase General function prediction only 76802840 Common - hypothetical protein NP4414A 21 COG3217 COG3217, Uncharacterized Fe-S protein General function prediction only 76801589 Common - signal-transducing histidine kinase; PAS/PAC domain protein NP1882A 106 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76802913 Nonpathogen - hypothetical protein NP4560A 2 None None None 76801825 Nonpathogen - hypothetical protein NP2364A 3 None None None 76801990 Nonpathogen - hypothetical protein NP2696A 3 None None None 76801619 Common tp57 transport protein 57 (probable polysaccharide biosynthesis transport protein) NP1944A 42 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 76802887 Nonpathogen - hypothetical protein NP4508A 2 None None None 76802849 Common prpB_2 probable carboxyvinyl-carboxyphosphonate phosphorylmutase 2 (carboxyphosphonoenolpyruvate phosphonomutase) NP4432A 134 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 76802546 Nonpathogen - hypothetical protein NP3822A 4 COG3837 COG3837, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 76801607 Common - sugar metabolism cluster protein NP1918A 2 COG1409 Icc, Predicted phosphohydrolases General function prediction only 76801322 Nonpathogen - homolog to 6-pyruvoyltetrahydropterin synthase (4.2.3.12) NP1342A 6 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 76801411 Nonpathogen - probable transcription regulator NP1522A 14 COG1846 MarR, Transcriptional regulators Transcription 76803299 Nonpathogen - hypothetical protein NP5344A 1 None None None 76801408 Common rad50 chromosome segregation protein NP1516A 148 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 76802390 Common galE_3 nucleoside-diphosphate-sugar epimerase 3 (probable UDP-glucose 4-epimerase ) NP3504A 226 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 76801442 Nonpathogen - peroxiredoxin homolog NP1584A 8 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 76802387 Common gyrB DNA topoisomerase II subunit B (DNA gyrase) NP3498A 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 76802732 Common msc_6 probable mechanosensitive channel NP4196A 14 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 76802070 Common - phosphate acetyltransferase domain protein NP2856A 68 COG0857 Pta, BioD-like N-terminal domain of phosphotransacetylase General function prediction only 76803056 Nonpathogen - conserved rpl operon protein NP4852A 20 COG2106 COG2106, Uncharacterized conserved protein Function unknown 76803026 Nonpathogen - hypothetical protein NP4792A 3 None None None 76803180 Nonpathogen - hypothetical protein NP5104A 3 None None None 76802325 Common htr33 transducer protein htr33 NP3374A 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 76801738 Nonpathogen - hypothetical protein NP2188A 4 None None None 76802883 Common cysG1 siroheme synthase (precorrin-2 oxidase ; ferrochelatase ) NP4500A 61 COG1648 CysG, Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) Coenzyme metabolism 76801586 Nonpathogen - hypothetical protein NP1876A 2 COG3430 COG3430, Uncharacterized protein conserved in archaea Function unknown 76802355 Common fadA_4 enoyl-CoA hydratase I 4 NP3434A 186 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 76801620 Common - hypothetical protein NP1948A 25 COG1213 COG1213, Predicted sugar nucleotidyltransferases Cell envelope biogenesis, outer membrane 76802803 Nonpathogen - hypothetical protein NP4338A 2 None None None 76802699 Common pgk phosphoglycerate kinase NP4130A 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 76802300 Nonpathogen - hypothetical protein NP3322A 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 76802930 Common gcvP2 glycine dehydrogenase subunit 2 NP4594A 173 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 76801875 Nonpathogen - hypothetical protein NP2464A 15 COG1361 COG1361, S-layer domain Cell envelope biogenesis, outer membrane 76802380 Nonpathogen - hypothetical protein NP3484A 2 None None None 76802573 Common - predicted helicase NP3876A 128 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 76802425 Nonpathogen - hypothetical protein NP3574A 1 None None None 76802436 Nonpathogen - probable transcription regulator NP3596A 4 COG4190 COG4190, Predicted transcriptional regulator Transcription 76802891 Common - probable ferredoxin-NAD+ reductase 2 NP4516A 220 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 76801421 Common cmo_2 molybdopterin-based tungsten cofactor biosynthesis protein 2 NP1542A 198 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 76802655 Common phr_1 deoxyribodipyrimidine photolyase NP4042A 132 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 76802814 Common ugpQ glycerophosphodiester phosphodiesterase NP4360A 136 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 76801917 Common - probable stress response protein NP2550A 92 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 76802739 Common - predicted crotonobetainyl-CoA:carnitine CoA-transferase /alpha-methylacyl-CoA racemase 2 NP4210A 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 76802054 Common mrp_1 ATP-binding protein Mrp 1 NP2824A 236 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 76802690 Common galE_2 nucleoside-diphosphate-sugar epimerase 2 (probable UDP-glucose 4-epimerase ) NP4112A 231 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 76801435 Nonpathogen - hypothetical protein NP1570A 5 COG2391 COG2391, Predicted transporter component General function prediction only 76802835 Nonpathogen - hypothetical protein NP4404A 2 None None None 76802012 Common - hypothetical protein NP2740A 23 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 76800898 Common mer3_1 ski2-like helicase NP0492A 150 COG1204 COG1204, Superfamily II helicase General function prediction only 76801286 Common tp33 transporter 33 (probable phosphate/sulfate permease) NP1270A 75 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 76800702 Nonpathogen rpl40e 50S ribosomal protein L40e NP0094A 23 COG1552 RPL40A, Ribosomal protein L40E Translation, ribosomal structure and biogenesis 76802776 Nonpathogen - hypothetical protein NP4284A 3 None None None 76802024 Common - hypothetical protein NP2764A 49 COG3332 COG3332, Uncharacterized conserved protein Function unknown 76801082 Nonpathogen - hypothetical protein NP0860A 13 COG3366 COG3366, Uncharacterized protein conserved in archaea Function unknown 76802415 Nonpathogen - homolog to major facilitator family transporter NP3554A 1 None None None 76800825 Nonpathogen - hypothetical protein NP0342A 14 COG2450 COG2450, Uncharacterized conserved protein Function unknown 76802374 Common psmB proteasome beta subunit NP3472A 47 COG0638 PRE1, 20S proteasome, alpha and beta subunits Posttranslational modification, protein turnover, chaperones 76801910 Common bdbD probable disulfide bond formation protein NP2536A 38 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 76801428 Nonpathogen - hypothetical protein NP1556A 2 None None None 76802247 Nonpathogen - hypothetical protein NP3214A 4 None None None 76802119 Common tp36 NRAMP-family transporter NP2956A 118 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 76802369 Common hchA probable chaperone protein NP3462A 76 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 76802074 Common abc19a ABC-type transport system ATP-binding protein (probable substrates zinc/manganese/metal ions) 1 NP2864A 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 76801489 Nonpathogen - hypothetical protein NP1680A 1 None None None 76802973 Nonpathogen - hypothetical protein NP4682A 2 None None None 76801153 Common - protein N-acetyltransferase homolog NP1004A 57 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 76802702 Common abc05a2 ABC-type transport system ATP-binding protein II (probable substrates branched-chain/neutral amino acids) 1 NP4136A 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 76802397 Common pyrB aspartate carbamoyltransferase catalytic subunit NP3518A 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 76802183 Nonpathogen - hypothetical protein NP3086A 4 None None None 76801653 Common ureD urease accessory protein NP2016A 66 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 76801951 Common - transcription regulator NP2618A 114 COG1414 IclR, Transcriptional regulator Transcription 76802342 Nonpathogen - hypothetical protein NP3408A 4 None None None 76801957 Common hbd_1 3-hydroxyacyl-CoA dehydrogenase 1 NP2630A 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 76801108 Nonpathogen - hypothetical protein NP0912A 3 None None None 76801225 Common nirA_2 probable ferredoxin--nitrite reductase 2 NP1146A 161 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 76802212 Common - probable stress response protein NP3144A 129 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 76800818 Common glyS glycyl-tRNA synthetase NP0328A 90 COG0423 GRS1, Glycyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 76802711 Common - hypothetical protein NP4154A 60 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 76800925 Common thiD phosphomethylpyrimidine kinase NP0546A 218 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 76802856 Nonpathogen - hypothetical protein NP4446A 21 COG1784 COG1784, Predicted membrane protein Function unknown 76801749 Nonpathogen - hypothetical protein NP2212A 4 None None None 76801469 Common - protein N-acetyltransferase homolog NP1638A 6 COG3153 COG3153, Predicted acetyltransferase General function prediction only 76802688 Nonpathogen - hypothetical protein NP4108A 1 None None None 76802683 Nonpathogen - hypothetical protein NP4098A 1 None None None 76802634 Nonpathogen - hypothetical protein NP4000A 2 None None None 76803288 Common - hypothetical protein NP5322A 144 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 76801882 Common tdk thymidylate kinase NP2478A 231 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 76801545 Common gltB glutamate synthase , large subunit NP1794A 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 76800863 Nonpathogen - hypothetical protein NP0418A 5 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 76801095 Nonpathogen - hypothetical protein NP0886A 1 None None None 76802109 Common fadA_7 enoyl-CoA hydratase I 7 NP2936A 131 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 76801550 Common - signal-transducing histidine kinase; PAS/PAC domain protein NP1804A 165 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76802572 Common - probable restriction/modification enzyme NP3874A 55 None None None 76801145 Nonpathogen - hypothetical protein NP0988A 1 None None None 76803011 Common - probable dehydrogenase/ reductase 14 NP4762A 36 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 76803279 Nonpathogen cobY GTP:adenosylcobinamide-phosphate guanylyltransferase NP5304A 25 COG2266 COG2266, GTP:adenosylcobinamide-phosphate guanylyltransferase Coenzyme metabolism 76801181 Nonpathogen - hypothetical protein NP1058A 1 None None None 76800938 Nonpathogen - hypothetical protein NP0572A 14 COG3837 COG3837, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 76802921 Common - predicted transporter (predicted permease) NP4576A 13 COG0628 PerM, Predicted permease General function prediction only 76802879 Common gldA glycerol-1-phosphate dehydrogenase [NAD(P)] NP4492A 135 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 76802796 Nonpathogen - hypothetical protein NP4324A 17 COG1849 COG1849, Uncharacterized protein conserved in archaea Function unknown 76801731 Common cheB protein-glutamate methylesterase NP2174A 219 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 76802486 Common - hypothetical protein NP3700A 6 None None None 76803213 Common - homolog 8 to S-adenosylmethionine-dependent methyltransferase 3 NP5170A 87 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 76803112 Common aor_1 aldehyde ferredoxin oxidoreductase 1 NP4964A 57 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 76800912 Nonpathogen - hypothetical protein NP0520A 2 None None None 76801078 Common - hypothetical protein NP0852A 43 COG1656 COG1656, Uncharacterized conserved protein Function unknown 76801502 Common pyrC dihydroorotase NP1706A 211 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 76801712 Nonpathogen - hypothetical protein NP2136A 3 None None None 76802935 Nonpathogen - hypothetical protein NP4604A 2 None None None 76802510 Common acyP acylphosphatase NP3750A 123 COG1254 AcyP, Acylphosphatases Energy production and conversion 76802793 Nonpathogen - hypothetical protein NP4318A 18 COG1885 COG1885, Uncharacterized protein conserved in archaea Function unknown 76801267 Common - homolog to cytochrome-b5 reductase NP1230A 10 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 76802563 Nonpathogen - hypothetical protein NP3856A 2 None None None 76802248 Common - hexosyltransferase 1 NP3216A 152 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 76803015 Common crtB geranylgeranyl-diphosphate geranylgeranyltransferase (phytoene synthase) NP4770A 108 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 76802888 Nonpathogen - hypothetical protein NP4510A 4 None None None 76801212 Common cbiF precorrin-4 C11-methyltransferase NP1120A 201 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 76800673 Common - probable stress response protein NP0036A 172 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 76802753 Common - homolog to ABC-type transport system periplasmic substrate-binding protein (probable substrates branched-chain/neutral amino acids amide) 4 NP4238A 37 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 76802726 Common - AAA-type ATPase (transitional ATPase homolog) NP4184A 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 76802980 Common - signal-transducing histidine kinase; PAS/PAC domain protein NP4696A 198 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76802532 Nonpathogen - hypothetical protein NP3794A 6 None None None 76801481 Nonpathogen - hypothetical protein NP1664A 3 None None None 76801725 Nonpathogen - conserved fla operon protein NP2162A 4 COG2469 COG2469, Uncharacterized conserved protein Function unknown 76800861 Common - hypothetical protein NP0414A 88 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 76800716 Common rps12P 30S ribosomal protein S12P NP0122A 173 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 76801344 Nonpathogen phoU_5 probable transport system regulatory protein (probable substrate phosphate) NP1386A 26 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 76800711 Common rpoB1 DNA-directed RNA polymerase subunit B' NP0112A 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 76802996 Common abc20a ABC-type transport system ATP-binding protein (probable substrates zinc/manganese/metal ions) 2 NP4730A 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 76801889 Common gatD glutamyl-tRNA(Gln) amidotransferase subunit D NP2492A 137 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 76802866 Common - hypothetical protein NP4466A 25 COG2855 COG2855, Predicted membrane protein Function unknown 76801774 Common - hypothetical protein NP2262A 34 COG3253 COG3253, Uncharacterized conserved protein Function unknown 76802030 Nonpathogen - hypothetical protein NP2776A 1 None None None 76803182 Nonpathogen - hypothetical protein NP5108A 2 None None None 76802207 Common htr24 transducer protein htr24 NP3134A 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 76801699 Common - hypothetical protein NP2110A 9 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 76801674 Nonpathogen - hypothetical protein NP2058A 1 None None None 76801961 Common cbs_5 CBS domain protein 5 NP2638A 65 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 76802365 Common - hypothetical protein NP3454A 124 COG0432 COG0432, Uncharacterized conserved protein Function unknown 76802006 Nonpathogen - menaquinone operon protein NP2728A 1 None None None 76802097 Common - transmembrane protein (homolog 3 to type II secretion system proteins TadC) NP2910A 29 COG1955 FlaJ, Archaeal flagella assembly protein J Cell motility and secretion / Intracellular trafficking and secretion 76801188 Common - predicted cell surface protein/ lipoprotein NP1072A 104 COG1520 COG1520, FOG: WD40-like repeat Function unknown 76802389 Common trpB_2 tryptophan synthase subunit beta NP3502A 226 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 76801949 Nonpathogen - homolog to stress response protein NP2614A 11 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 76801963 Common tp24 transporter 24 (drug/metabolite family transporter 2) NP2642A 18 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 76801432 Nonpathogen - predicted DNA binding protein NP1564A 8 COG3413 COG3413, Predicted DNA binding protein General function prediction only 76801689 Nonpathogen flg_3 flagellin precursor 3 NP2090A 8 COG1681 FlaB, Archaeal flagellins Cell motility and secretion 76801064 Common aspC_4 probable aspartate aminotransferase 4 NP0824A 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 76800791 Common serA phosphoglycerate dehydrogenase NP0272A 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 76801942 Common - hypothetical protein NP2600A 81 COG0393 COG0393, Uncharacterized conserved protein Function unknown 76801859 Common - asparaginase NP2432A 84 COG1446 COG1446, Asparaginase Amino acid transport and metabolism 76800968 Nonpathogen - hypothetical protein NP0632A 1 None None None 76802565 Common relA probable GTP pyrophosphokinase NP3860A 173 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 76803132 Common purS phosphoribosylformylglycinamidine synthase , PurS component NP5008A 28 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 76803049 Nonpathogen - hypothetical protein NP4838A 3 None None None 76803304 Nonpathogen - hypothetical protein NP5354A 1 None None None 76801595 Nonpathogen - predicted transporter (predicted permease) NP1894A 2 COG0628 PerM, Predicted permease General function prediction only 76801700 Common - hypothetical protein NP2112A 48 COG3268 COG3268, Uncharacterized conserved protein Function unknown 76801635 Common abc14s ABC-type transport system periplasmic phosphate-binding protein (probable substrate phosphate) 1 NP1978A 144 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 76802382 Common sppA_2 probable signal peptide peptidase NP3488A 47 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 76802496 Common - hypothetical protein NP3722A 45 COG2035 COG2035, Predicted membrane protein Function unknown 76801565 Common - homolog 2 to Rieske iron sulfur protein NP1834A 5 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 76801129 Common dcd_2 deoxyuridine 5'-triphosphate nucleotidohydrolase NP0954A 24 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 76801498 Nonpathogen - hypothetical protein NP1698A 3 None None None 76801397 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase NP1494A 137 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 76800687 Common - probable ABC-type transport system periplasmic substrate-binding protein (probable substrate iron(III)) 2 NP0064A 85 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 76802950 Nonpathogen - truncated IS1341-type transposase NP4636A 4 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 76803281 Common cbiB cobalamine biosynthesis protein (adenosylcobinamide biosynthesis protein) NP5308A 120 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 76800745 Nonpathogen - hypothetical protein NP0180A 1 None None None 76801301 Nonpathogen - hypothetical protein NP1300A 4 None None None 76801110 Common fadB_4 probable enoyl-CoA hydratase II 4 NP0916A 88 COG2030 MaoC, Acyl dehydratase Lipid metabolism 76802261 Nonpathogen - hypothetical protein NP3242A 1 None None None 76801995 Nonpathogen - hypothetical protein NP2706A 1 None None None 76802624 Common pheA1 chorismate mutase NP3980A 46 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 76801648 Nonpathogen - hypothetical protein NP2006A 1 None None None 76801976 Common tpa01 transport ATPase 1 (probable substrates copper/metal cation) NP2668A 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 76803005 Common cysK_1 cysteine synthase 1 NP4748A 221 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 76801067 Common tp49_7 putative monovalent cation/H+ antiporter subunit D NP0830A 207 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 76801256 Nonpathogen - homolog 3 to KaiC-like transcriptional regulator NP1208A 4 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 76802038 Common - hypothetical protein NP2792A 113 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 76801210 Common cbiH_1 precorrin-3B C17-methyltransferase 1 NP1116A 130 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 76803100 Common mrp_2 ATP-binding protein Mrp 2 NP4940A 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 76801510 Common - predicted iron-sulfur protein (probable electron transport protein)/ iron-sulfur protein (probable glycolate oxidase iron-sulfur subunit) NP1722A 146 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 76803001 Nonpathogen - hypothetical protein NP4740A 2 None None None 76802227 Nonpathogen - hypothetical protein NP3174A 1 None None None 76800832 Common - probable methyltransferase NP0356A 94 COG2519 GCD14, tRNA(1-methyladenosine) methyltransferase and related methyltransferases Translation, ribosomal structure and biogenesis 76802611 Common hcp_1 halocyanin 1 NP3954A 9 COG3794 PetE, Plastocyanin Energy production and conversion 76801117 Common - probable helicase NP0930A 124 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 76802166 Common - hypothetical protein NP3052A 14 COG4357 COG4357, Uncharacterized conserved protein Function unknown 76803073 Common rpl6p 50S ribosomal protein L6P NP4886A 164 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 76801023 Nonpathogen - hypothetical protein NP0742A 1 None None None 76800675 Common tp01_2 transport system 1 (probable substrates cationic amino acids), subunit 2 NP0040A 180 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 76802409 Common tp43 transporter 43 (probable ferrous iron transport protein) NP3542A 83 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 76803085 Common adk adenylate kinase NP4910A 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 76801283 Nonpathogen - hypothetical protein NP1262A 1 None None None 76802292 Nonpathogen - hypothetical protein NP3306A 1 None None None 76801852 Common nadA quinolinate synthetase NP2418A 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 76801349 Common abc21a ABC-type transport system ATP-binding protein (probable substrate cobalt) NP1396A 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 76800891 Common - conserved polA operon protein (predicted DNA-binding protein) NP0478A 25 COG1661 COG1661, Predicted DNA-binding protein with PD1-like DNA-binding motif General function prediction only 76802697 Common - predicted transporter NP4126A 97 COG0679 COG0679, Predicted permeases General function prediction only 76801272 Nonpathogen - hypothetical protein NP1240A 1 None None None 76802919 Common - IS1341-type transposase NP4572A 59 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 76801138 Common - IS1341-type transposase NP0974A 48 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 76803081 Common trkA potassium transporter peripheral membrane component NP4902A 159 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 76802501 Nonpathogen - hypothetical protein NP3732A 1 None None None 76801276 Common - hypothetical protein NP1248A 12 COG2259 COG2259, Predicted membrane protein Function unknown 76801000 Common pheS phenylalanyl-tRNA synthetase subunit alpha NP0696A 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 76801909 Nonpathogen - probable transcription regulator NP2534A 12 COG1777 COG1777, Predicted transcriptional regulators Transcription 76802144 Nonpathogen - hypothetical protein NP3006A 1 None None None 76800694 Common - transcription regulator NP0078A 135 COG1522 Lrp, Transcriptional regulators Transcription 76801361 Common - hypothetical protein NP1420A 240 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 76802485 Common - predicted hydrolase NP3698A 155 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 76802627 Nonpathogen - hypothetical protein NP3986A 16 COG1371 COG1371, Uncharacterized conserved protein Function unknown 76802279 Common - homolog to predicted lipoprotein NP3280A 6 COG1724 COG1724, Predicted periplasmic or secreted lipoprotein Cell motility and secretion 76801193 Common abc25a ABC-type transport system ATP-binding protein (probable substrate copper) 3 NP1082A 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 76803169 Nonpathogen - conserved rpo operon protein NP5082A 10 COG1412 COG1412, Uncharacterized proteins of PilT N-term./Vapc superfamily General function prediction only 76801092 Common - hypothetical protein NP0880A 13 None None None 76802136 Nonpathogen - hypothetical protein NP2990A 1 None None None 76801143 Common - hypothetical protein NP0984A 72 COG2391 COG2391, Predicted transporter component General function prediction only 76802527 Nonpathogen fen flap endonuclease-1 NP3784A 36 COG0258 Exo, 5'-3' exonuclease (including N-terminal domain of PolI) DNA replication, recombination, and repair 76801605 Common - signal-transducing histidine kinase; PAS/PAC domain protein NP1914A 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76802618 Nonpathogen - hypothetical protein NP3968A 3 None None None 76802475 Common ksgA dimethyladenosine transferase NP3678A 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 76801364 Common apt_1 adenine phosphoribosyltransferase NP1426A 41 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 76802159 Common - IS1341-type transposase NP3036A 50 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 76800872 Common - homolog 3 to rad50 ATPase NP0440A 162 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 76800916 Nonpathogen - probable cell surface glycoprotein NP0528A 2 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 76803118 Nonpathogen - hypothetical protein NP4978A 1 None None None 76801356 Common - hypothetical protein NP1410A 131 COG1739 COG1739, Uncharacterized conserved protein Function unknown 76802911 Common idsA_1 probable multifunctional short/ long-chain (E)-prenyl diphosphate synthase NP4556A 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 76800991 Common - putative ATPase RIL NP0678A 249 COG1245 COG1245, Predicted ATPase, RNase L inhibitor (RLI) homolog General function prediction only 76803269 Nonpathogen - hypothetical protein NP5284A 2 None None None 76801047 Common nifS_2 probable cysteine desulfurase 2, class V aminotransferase NP0790A 231 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 76800843 Nonpathogen - hypothetical protein NP0378A 9 None None None 76802499 Nonpathogen - hypothetical protein NP3728A 1 None None None 76801016 Common - serine/threonine protein phosphatase ; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) NP0728A 91 COG0622 COG0622, Predicted phosphoesterase General function prediction only 76801237 Common entB_2 probable isochorismatase 2; probable nicotinamidase 2; probable N-carbamoylsarcosine amidase 2 NP1170A 153 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 76802228 Nonpathogen - hypothetical protein NP3176A 4 None None None 76801335 Nonpathogen rps6R 30S ribosomal protein S6e NP1368A 34 COG2125 RPS6A, Ribosomal protein S6E (S10) Translation, ribosomal structure and biogenesis 76802734 Common rhl probable DNA repair helicase NP4200A 72 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 76801386 Common abc07a2 ABC-type transport system ATP-binding protein II (probable substrates branched-chain/neutral amino acids) 3 NP1470A 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 76801898 Common - probable KaiC-like transcriptional regulator 2 NP2510A 78 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 76801012 Nonpathogen - hypothetical protein NP0720A 3 None None None 76801161 Common atpI H(+)-transporting two-sector ATPase subunit I.a (A-type ATP synthase) NP1020A 50 COG1269 NtpI, Archaeal/vacuolar-type H+-ATPase subunit I Energy production and conversion 76802787 Common celM probable cellulase ; probable endo-1,3(4)-beta-glucanase NP4306A 87 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 76802824 Common ccmF cytochrome c-type biogenesis protein NP4380A 140 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 76802400 Common - nudix family protein NP3524A 32 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 76803258 Common argB acetylglutamate kinase NP5262A 211 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 76800978 Nonpathogen crtY lycopene cyclase NP0652A 7 None None None 76801311 Nonpathogen - hypothetical protein NP1320A 31 COG1395 COG1395, Predicted transcriptional regulator Transcription 76803231 Nonpathogen - transmembrane protein (homolog 5 to type II secretion system proteins TadC) NP5206A 5 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 76801753 Nonpathogen tfbA_2 transcription initiation factor TFB 2 NP2220A 34 COG1405 SUA7, Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB Transcription 76801902 Common - hypothetical protein NP2518A 41 COG1378 COG1378, Predicted transcriptional regulators Transcription 76802234 Nonpathogen - hypothetical protein NP3188A 4 COG1967 COG1967, Predicted membrane protein Function unknown 76803311 Nonpathogen - integrase homolog NP5368A 3 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 76802240 Common deoC deoxyribose-phosphate aldolase NP3200A 92 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 76800783 Common - probable amidase NP0256A 219 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 76800854 Common - homolog 1 to thiosulfate sulfurtransferase NP0400A 8 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 76802230 Common udp_2 uridine phosphorylase 2 NP3180A 103 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 76802743 Nonpathogen - peroxiredoxin homolog NP4218A 11 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 76803035 Common - IS1341-type transposase NP4810A 39 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 76801529 Nonpathogen - hypothetical protein NP1760A 1 None None None 76802009 Common menA 1,4-dihydroxy-2-naphthoate octaprenyltransferase NP2734A 82 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 76801294 Nonpathogen - hypothetical protein NP1286A 3 None None None 76800907 Nonpathogen - homolog to ABC-type phosphate transport system permease protein NP0510A 1 None None None 76803064 Nonpathogen rpmC 50S ribosomal protein L29 NP4868A 10 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 76801798 Common nuoL NADH dehydrogenase-like complex, subunit L NP2310A 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 76802529 Nonpathogen - hypothetical protein NP3788A 4 None None None 76802942 Nonpathogen - hypothetical protein NP4618A 1 None None None 76801206 Common cbiX_1 conserved cobalamin cluster protein CbiX 1 (probable ferredoxin-like iron-sulfur protein) NP1108A 110 COG2138 COG2138, Uncharacterized conserved protein Function unknown 76803093 Common ilvD dihydroxy-acid dehydratase NP4926A 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 76802307 Common trpD anthranilate phosphoribosyltransferase NP3338A 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 76802085 Nonpathogen - hypothetical protein NP2886A 8 None None None 76801487 Nonpathogen - hypothetical protein NP1676A 4 None None None 76801456 Nonpathogen - hypothetical protein NP1612A 3 None None None 76801477 Nonpathogen - hypothetical protein NP1654A 4 None None None 76803194 Common acs_4 acyl-CoA synthetase I 4 NP5132A 215 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 76801988 Nonpathogen - hypothetical protein NP2692A 4 None None None 76802060 Nonpathogen rpl18R 50S ribosomal protein L18e NP2836A 34 COG1727 RPL18A, Ribosomal protein L18E Translation, ribosomal structure and biogenesis 76800879 Nonpathogen - hypothetical protein NP0454A 1 None None None 76803274 Common ftsZ_5 cell division protein NP5294A 220 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 76802553 Nonpathogen - hypothetical protein NP3836A 4 None None None 76802583 Nonpathogen - hypothetical protein NP3896A 3 COG1497 COG1497, Predicted transcriptional regulator Transcription 76802959 Common glmS_1 glutamine--fructose-6-phosphate transaminase (isomerizing) 1 NP4654A 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 76801715 Nonpathogen - predicted nucleotide kinase NP2142A 21 COG1936 COG1936, Predicted nucleotide kinase (related to CMP and AMP kinases) Nucleotide transport and metabolism 76802126 Common - hypothetical protein NP2970A 15 COG2836 COG2836, Uncharacterized conserved protein Function unknown 76800885 Nonpathogen - hypothetical protein NP0466A 1 None None None 76802672 Common - hypothetical protein NP4076A 61 COG1432 COG1432, Uncharacterized conserved protein Function unknown 76802641 Nonpathogen - hypothetical protein NP4014A 1 None None None 76803189 Common - homolog 11 to S-adenosylmethionine-dependent methyltransferase 3 NP5122A 60 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 76803022 Nonpathogen - hypothetical protein NP4784A 2 None None None 76803307 Nonpathogen - hypothetical protein NP5360A 2 COG4233 COG4233, Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis Posttranslational modification, protein turnover, chaperones / Energy production and conversion 76800809 Common nadM1_2 nicotinamide-nucleotide adenylyltransferase 2 NP0310A 44 COG1056 NadR, Nicotinamide mononucleotide adenylyltransferase Coenzyme metabolism 76802932 Nonpathogen - hypothetical protein NP4598A 1 None None None 76801036 Nonpathogen - hypothetical protein NP0768A 4 None None None 76802337 Nonpathogen - hypothetical protein NP3398A 1 None None None 76802141 Nonpathogen - hypothetical protein NP3000A 6 None None None 76801246 Nonpathogen - hypothetical protein NP1188A 4 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 76803297 Nonpathogen - hypothetical protein NP5340A 1 None None None 76802428 Common abc02p_1 ABC-type transport system permease protein (probable substrates dipeptide/oligopeptide/nickel) 3 NP3580A 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 76800803 Nonpathogen - hypothetical protein NP0298A 1 None None None 76800940 Common engB GTP-binding protein NP0576A 160 COG0218 COG0218, Predicted GTPase General function prediction only 76800956 Nonpathogen - homolog to 5'-nucleotidase NP0608A 4 COG3975 COG3975, Predicted protease with the C-terminal PDZ domain General function prediction only 76803158 Common - IS1341-type transposase NP5060A 63 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 76802781 Nonpathogen coxB_3 cytochrome-c-like terminal oxidase , subunit II 3 NP4294A 22 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 76802364 Common - hypothetical protein NP3452A 53 COG2311 COG2311, Predicted membrane protein Function unknown 76800765 Nonpathogen - hypothetical protein NP0220A 18 COG3273 COG3273, Uncharacterized conserved protein Function unknown 76801042 Nonpathogen - hypothetical protein NP0780A 4 None None None 76802189 Common - homolog to stress response protein NP3098A 8 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 76802596 Common abc12s ABC-type transport system substrate-binding protein (probable substrate copper) 2 NP3922A 42 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 76801871 Common coxA_1 cytochrome-c-like terminal oxidase , subunit I 1 NP2456A 175 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 76801746 Nonpathogen - hypothetical protein NP2204A 1 None None None 76802833 Nonpathogen - hypothetical protein NP4400A 1 None None None 76801121 Common hcp_3 halocyanin 3 NP0938A 8 COG3794 PetE, Plastocyanin Energy production and conversion 76802084 Nonpathogen - hypothetical protein NP2884A 3 None None None 76802646 Common aspC_1 PLP-dependent aminotransferase (probable aspartate aminotransferase 1) NP4024A 241 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 76800729 Nonpathogen - hypothetical protein NP0148A 3 None None None 76803039 Nonpathogen - hypothetical protein NP4818A 3 None None None 76802534 Common tp11 major facilitator family transporter 1 (probable oxalate/formate antiporter) NP3798A 78 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 76802869 Common - hypothetical protein NP4472A 131 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 76802103 Common thyA thymidylate synthase NP2924A 140 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 76803240 Nonpathogen - peptidyl-tRNA hydrolase NP5224A 35 COG1990 COG1990, Uncharacterized conserved protein Function unknown 76801676 Nonpathogen flpA fibrillarin NP2062A 34 COG1889 NOP1, Fibrillarin-like rRNA methylase Translation, ribosomal structure and biogenesis 76801887 Nonpathogen - hypothetical protein NP2488A 2 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 76801678 Common - glutaredoxin homolog NP2066A 127 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 76801484 Nonpathogen - hypothetical protein NP1670A 10 COG4801 COG4801, Predicted acyltransferase General function prediction only 76802778 Common ctaB_2 heme O oxidase N-terminal domain homolog / protoheme IX farnesyltransferase NP4288A 165 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 76802941 Nonpathogen - probable cell surface glycoprotein NP4616A 1 None None None 76803149 Common truA tRNA pseudouridine synthase A NP5042A 213 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 76803175 Nonpathogen - hypothetical protein NP5094A 4 None None None 76801880 Nonpathogen - transcription regulator NP2474A 6 None None None 76802051 Nonpathogen - hypothetical protein NP2818A 1 None None None 76800922 Common tp53_3 predicted TRAP-type transport system permease protein NP0540A 89 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 76802490 Common - predicted NAD-binding protein 3 (probable Kef-type transporter subunit) NP3708A 71 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 76800937 Common ths_2 thermosome subunit 2 (beta subunit) NP0570A 244 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 76801906 Nonpathogen - truncated IS1341-type transposase NP2526A 1 None None None 76802420 Nonpathogen - hypothetical protein NP3564A 2 COG3359 COG3359, Predicted exonuclease DNA replication, recombination, and repair 76802971 Nonpathogen - sugar metabolism cluster protein NP4678A 2 COG5652 COG5652, Predicted integral membrane protein Function unknown 76802788 Nonpathogen - snRNP homolog NP4308A 27 COG1958 LSM1, Small nuclear ribonucleoprotein (snRNP) homolog Transcription 76802568 Nonpathogen - hypothetical protein NP3866A 1 None None None 76803030 Nonpathogen - hypothetical protein NP4800A 5 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 76801338 Common dfp phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase NP1374A 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 76802465 Common dpsA DNA-binding protein, ferretin-like domain protein NP3658A 59 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 76801657 Nonpathogen - triphosphoribosyl-dephospho-CoA synthase NP2024A 19 COG1767 CitG, Triphosphoribosyl-dephospho-CoA synthetase Coenzyme metabolism 76803313 Common cxp_2 carboxypeptidase (similarity to Glutamate carboxypeptidase , Carboxypeptidase G2) NP5372A 166 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 76802277 Common - hypothetical protein NP3276A 15 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 76802216 Common - hypothetical protein NP3152A 56 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 76801629 Common - hypothetical protein NP1966A 10 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 76802986 Nonpathogen - hypothetical protein NP4708A 3 None None None 76800910 Common - response regulator NP0516A 225 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 76801612 Common - hexosyltransferase 4 NP1928A 216 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 76800753 Nonpathogen - hypothetical protein NP0196A 8 COG5431 COG5431, Uncharacterized metal-binding protein Function unknown 76802860 Common rpl11p 50S ribosomal protein L11P NP4454A 231 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 76800892 Nonpathogen - conserved polA cluster protein NP0480A 1 None None None 76803226 Nonpathogen - hypothetical protein NP5196A 1 None None None 76801845 Common ftsZ_4 cell division protein NP2404A 140 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 76802285 Nonpathogen - hypothetical protein NP3292A 1 None None None 76802761 Common acd_4 acyl-CoA dehydrogenase 4 NP4254A 161 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 76802454 Nonpathogen - hypothetical protein NP3634A 3 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 76801836 Common graD_5 sugar nucleotidyltransferase (probable glucose-1-phosphate thymidylyltransferase ) 4 NP2386A 186 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 76802817 Nonpathogen - conserved acc operon protein NP4366A 3 None None None 76801086 Nonpathogen - conserved coaE operon protein NP0868A 22 COG1931 COG1931, Uncharacterized protein conserved in archaea Function unknown 76802717 Common - probable dehydrogenase/ reductase 6 NP4166A 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 76802013 Common - signal-transducing histidine kinase; PAS/PAC domain protein NP2742A 173 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76802203 Nonpathogen - probable transcription regulator NP3126A 13 COG1846 MarR, Transcriptional regulators Transcription 76802264 Nonpathogen - hypothetical protein NP3248A 1 None None None 76801379 Common aatA aspartyl-tRNA(Asn) amidotransferase subunit A NP1456A 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 76802638 Nonpathogen - hypothetical protein NP4008A 3 None None None 76802036 Common - hypothetical protein NP2788A 20 COG3361 COG3361, Uncharacterized conserved protein Function unknown 76801570 Common ggt gamma-glutamyltransferase NP1844A 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 76801964 Nonpathogen - hypothetical protein NP2644A 1 None None None 76801383 Common abc07s ABC-type transport system periplasmic substrate-binding protein (probable substrates branched-chain/neutral amino acids amide) 3 NP1464A 96 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 76802135 Nonpathogen - hypothetical protein NP2988A 2 None None None 76801164 Common atpC V-type ATP synthase subunit C NP1026A 32 COG1527 NtpC, Archaeal/vacuolar-type H+-ATPase subunit C Energy production and conversion 76801183 Common hisG ATP phosphoribosyltransferase NP1062A 212 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 76803129 Common abc03s ABC-type transport system periplasmic substrate-binding protein (probable substrate iron(III)) 1 NP5000A 108 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 76801751 Common - hypothetical protein NP2216A 26 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 76800828 Common sppA_1 probable signal peptide peptidase NP0348A 188 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 76801577 Nonpathogen - hypothetical protein NP1858A 1 None None None 76803232 Nonpathogen - hypothetical protein NP5208A 3 None None None 76803140 Common - probable stress response protein NP5024A 74 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 76803120 Common tif5B translation initiation factor IF-2 NP4982A 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 76801812 Nonpathogen - hypothetical protein NP2338A 1 None None None 76803058 Nonpathogen rpl4lp 50S ribosomal protein L4P NP4856A 34 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 76801341 Nonpathogen - hypothetical protein NP1380A 3 None None None 76802484 Common idsA_3 probable trifunctional short-chain (E)-prenyl diphosphate synthase (probable dimethylallyltransferase / probable geranyltranstransferase / probable farnesytranstransferase ) NP3696A 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 76803142 Nonpathogen - hypothetical protein NP5028A 4 COG2512 COG2512, Uncharacterized membrane-associated protein/domain Function unknown 76802558 Common - helicase homolog NP3846A 127 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 76802933 Nonpathogen - hypothetical protein NP4600A 2 None None None 76802310 Common trpG_1 anthranilate synthase , component II 1 NP3344A 231 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 76801218 Common - hypothetical protein NP1132A 26 COG3269 COG3269, Predicted RNA-binding protein, contains TRAM domain General function prediction only 76801373 Nonpathogen - hypothetical protein NP1444A 1 None None None 76801312 Common htr27 transducer protein htr27 NP1322A 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 76801956 Common acd_2 acyl-CoA dehydrogenase 2 NP2628A 160 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 76802825 Nonpathogen - hypothetical protein NP4382A 2 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 76801057 Common ftsZ_1 cell division protein FtsZ NP0810A 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 76800693 Common glnA_1 glutamate--ammonia ligase 1 NP0076A 223 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 76801035 Common abc01a_2 ABC-type transport system ATP-binding protein (probable substrates dipeptide/oligopeptide/nickel) I 2 NP0766A 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 76802903 Nonpathogen - hypothetical protein NP4540A 6 COG0456 RimI, Acetyltransferases General function prediction only 76802319 Nonpathogen - hypothetical protein NP3362A 4 None None None 76802703 Common abc05a1 ABC-type transport system ATP-binding protein I (probable substrates branched-chain/neutral amino acids) 1 NP4138A 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 76801500 Nonpathogen - hypothetical protein NP1702A 4 None None None 76802117 Common hyuB_1 N-methylhydantoinase (ATP-hydrolyzing) B 1 NP2952A 94 COG0146 HyuB, N-methylhydantoinase B/acetone carboxylase, alpha subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 76802096 Nonpathogen - hypothetical protein NP2908A 3 None None None 76802254 Common - homolog 2 to phycocyanobilin lyase subunit NP3228A 38 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 76802026 Nonpathogen - hypothetical protein NP2768A 2 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 76801622 Common - sugar metabolism cluster protein (sugar nucleotidyltransferase homolog) NP1952A 152 COG1213 COG1213, Predicted sugar nucleotidyltransferases Cell envelope biogenesis, outer membrane 76802357 Common acaB_4 acetyl-CoA C-acyltransferase 4 NP3438A 95 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 76802896 Common bdbC disulfide bond formation protein NP4526A 21 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 76802912 Common ppnK_2 probable NAD(+) kinase 2 (inorganic polyphosphate/ATP-NAD kinase) NP4558A 141 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 76802182 Nonpathogen - hypothetical protein NP3084A 1 None None None 76800917 Common tp18 major facilitator family transporter 8 NP0530A 19 None None None 76802892 Nonpathogen - hypothetical protein NP4518A 4 None None None 76802099 Nonpathogen - hypothetical protein NP2916A 1 None None None 76802302 Nonpathogen - hypothetical protein NP3326A 1 None None None 76802674 Common - transcription regulator NP4080A 68 COG0819 TenA, Putative transcription activator Transcription 76803018 Nonpathogen - hypothetical protein NP4776A 15 COG1432 COG1432, Uncharacterized conserved protein Function unknown 76803188 Common - signal-transducing histidine kinase; probable PAS/PAC domain protein NP5120A 185 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76801522 Common pykA pyruvate kinase NP1746A 222 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 76802607 Common - hydrolase (probable hydroxyacylglutathione hydrolase ) 6 NP3944A 103 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 76801763 Common aroD 3-dehydroquinate dehydratase NP2240A 48 COG0710 AroD, 3-dehydroquinate dehydratase Amino acid transport and metabolism 76802622 Common proB glutamate 5-kinase NP3976A 189 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 76801934 Common - anaerobic dehydrogenase subunit (probable iron-sulfur protein) NP2584A 141 COG1140 NarY, Nitrate reductase beta subunit Energy production and conversion 76802323 Nonpathogen - hypothetical protein NP3370A 4 COG3355 COG3355, Predicted transcriptional regulator Transcription 76802763 Common - transcription regulator NP4258A 108 COG1414 IclR, Transcriptional regulator Transcription 76801728 Common - conserved che operon protein (homolog 1 to phycocyanobilin lyase subunit ) NP2168A 58 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 76801460 Nonpathogen - H/ACA RNA-protein complex component Nop10p NP1620A 4 COG2260 COG2260, Predicted Zn-ribbon RNA-binding protein Translation, ribosomal structure and biogenesis 76801403 Common - signal-transducing histidine kinase NP1506A 186 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76801775 Nonpathogen - hypothetical protein NP2264A 1 None None None 76801413 Nonpathogen - hypothetical protein NP1526A 3 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 76801448 Common acd_5 acyl-CoA dehydrogenase 5 NP1596A 169 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 76801581 Nonpathogen - hypothetical protein NP1866A 3 None None None 76801596 Common - hypothetical protein NP1896A 120 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 76802045 Nonpathogen - hypothetical protein NP2806A 2 None None None 76801491 Nonpathogen tfbA_1 transcription initiation factor TFB 1 NP1684A 34 COG1405 SUA7, Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB Transcription 76802017 Common - hypothetical protein NP2750A 26 COG4276 COG4276, Uncharacterized conserved protein Function unknown 76802047 Common tyrS tyrosyl-tRNA synthetase NP2810A 91 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 76801736 Nonpathogen - hypothetical protein NP2184A 1 None None None 76800833 Nonpathogen - hypothetical protein NP0358A 2 None None None 76802579 Common - ATP-dependent DNA helicase NP3888A 44 COG1241 MCM2, Predicted ATPase involved in replication control, Cdc46/Mcm family DNA replication, recombination, and repair 76801543 Common radB DNA repair and recombination protein RadB NP1788A 242 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 76800821 Nonpathogen tif1A_2 translation initiation factor IF-1A NP0334A 34 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 76802464 Nonpathogen - hypothetical protein NP3656A 2 None None None 76802678 Nonpathogen - hypothetical protein NP4088A 1 None None None 76802791 Nonpathogen tif2b translation initiation factor IF-2 subunit beta NP4314A 34 COG1601 GCD7, Translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain Translation, ribosomal structure and biogenesis 76801323 Common - hexosyltransferase homolog 2 NP1344A 192 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 76802976 Nonpathogen - hypothetical protein NP4688A 4 COG1378 COG1378, Predicted transcriptional regulators Transcription 76800899 Nonpathogen ferC ferredoxin III NP0494A 4 COG1141 Fer, Ferredoxin Energy production and conversion 76802313 Nonpathogen - hypothetical protein NP3350A 8 COG0398 COG0398, Uncharacterized conserved protein Function unknown 76800780 Common - hypothetical protein NP0250A 64 COG3019 COG3019, Predicted metal-binding protein General function prediction only 76800725 Common - response regulator NP0140A 214 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 76801232 Common - probable dehydrogenase/ reductase 7 NP1160A 238 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 76803263 Nonpathogen - transcription regulator NP5272A 10 COG3355 COG3355, Predicted transcriptional regulator Transcription 76801996 Common perA catalase / peroxidase NP2708A 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 76801807 Nonpathogen - hypothetical protein NP2328A 1 None None None 76800709 Nonpathogen rpoH DNA-directed RNA polymerase subunit H NP0108A 31 COG2012 RPB5, DNA-directed RNA polymerase, subunit H, RpoH/RPB5 Transcription 76802991 Nonpathogen - homolog 1 to mannose-1-phosphate guanylyltransferase (GDP) NP4718A 4 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 76802619 Common - hydrolase (probable hydroxyacylglutathione hydrolase ) 3 NP3970A 25 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 76803192 Common acs_3 acyl-CoA synthetase I 3 NP5128A 218 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 76800682 Common nadE_2 NAD(+) synthase (glutamine-hydrolyzing) 2 NP0054A 216 COG0171 NadE, NAD synthase Coenzyme metabolism 76802441 Common - multidrug efflux protein norM homolog NP3606A 80 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 76802154 Nonpathogen - hypothetical protein NP3026A 2 COG4354 COG4354, Predicted bile acid beta-glucosidase Carbohydrate transport and metabolism 76801662 Common - probable stress response protein NP2034A 30 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 76801606 Common gtl_2 glycosyltransferase 2 NP1916A 54 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 76802225 Common etfB electron transfer flavoprotein, beta subunit NP3170A 149 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 76803065 Nonpathogen rnp1 ribonuclease P protein component 1 NP4870A 21 COG1588 POP4, RNase P/RNase MRP subunit p29 Translation, ribosomal structure and biogenesis 76802505 Nonpathogen - hypothetical protein NP3740A 34 COG1500 COG1500, Predicted exosome subunit Translation, ribosomal structure and biogenesis 76801010 Common - hypothetical protein NP0716A 16 COG4399 COG4399, Uncharacterized protein conserved in bacteria Function unknown 76803276 Nonpathogen - predicted DNA binding protein NP5298A 2 COG3413 COG3413, Predicted DNA binding protein General function prediction only 76801072 Nonpathogen tp49_2 pH adaptation potassium efflux system protein F; sodium/hydrogen antiporter subunit F NP0840A 18 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 76803099 Nonpathogen rpoM_2 probable DNA-directed RNA polymerase subunit M 2 NP4938A 33 COG1594 RPB9, DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS Transcription 76800801 Nonpathogen - hypothetical protein NP0292A 2 COG4502 COG4502, Uncharacterized protein conserved in bacteria Function unknown 76801019 Nonpathogen - hypothetical protein NP0734A 9 COG2138 COG2138, Uncharacterized conserved protein Function unknown 76801773 Common acaB_6 acetyl-CoA C-acyltransferase 6 NP2260A 184 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 76802805 Nonpathogen - hypothetical protein NP4342A 3 None None None 76801874 Common - hypothetical protein NP2462A 39 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 76801896 Nonpathogen tgtA2 queuine/archaeosine tRNA-ribosyltransferase II NP2506A 32 COG1549 COG1549, Queuine tRNA-ribosyltransferases, contain PUA domain Translation, ribosomal structure and biogenesis 76802005 Common menD 2-oxoglutarate decarboxylase ; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase NP2726A 170 COG1165 MenD, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase Coenzyme metabolism 76800985 Nonpathogen - hypothetical protein NP0666A 3 None None None 76801711 Common hcpE_1 probable 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase 1; probable 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase 1 NP2134A 180 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 76803251 Nonpathogen - hypothetical protein NP5246A 2 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 76801030 Common - predicted F420-dependent NADP reductase NP0756A 32 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 76802724 Nonpathogen - hypothetical protein NP4180A 4 None None None 76801709 Common - IS1341-type transposase NP2130A 52 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 76802570 Nonpathogen - hypothetical protein NP3870A 3 None None None 76802444 Nonpathogen - hypothetical protein NP3612A 1 None None None 76800851 Nonpathogen - hypothetical protein NP0394A 4 None None None 76802164 Nonpathogen - hypothetical protein NP3048A 1 None None None 76803115 Nonpathogen - hypothetical protein NP4972A 2 None None None 76802308 Common trpF phosphoribosylanthranilate isomerase NP3340A 171 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 76802752 Common bioB biotin synthase NP4236A 185 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 76801834 Common tp04 transporter 4 (probable substrates cationic amino acids) NP2382A 132 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 76800670 Common - probable metalloprotease / CBS domain protein NP0030A 181 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 76803162 Common - protein N-acetyltransferase homolog NP5068A 43 COG0456 RimI, Acetyltransferases General function prediction only 76803301 Common - hypothetical protein NP5348A 2 COG5177 COG5177, Uncharacterized conserved protein Function unknown 76801304 Common rad3b DNA repair helicase homolog NP1306A 45 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 76802609 Common glo_1 lyase/ dioxygenase 1 (probable lactoylglutathione lyase , aromatic compounds dioxygenase ) NP3948A 44 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 76802901 Nonpathogen - hypothetical protein NP4536A 4 None None None 76802741 Common acd_12 acyl-CoA dehydrogenase 12 NP4214A 155 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 76801144 Common - hypothetical protein NP0986A 26 COG2928 COG2928, Uncharacterized conserved protein Function unknown 76801366 Common - probable stress response protein NP1430A 122 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 76802520 Common folP_2 dihydropteroate synthase 2 NP3770A 216 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 76802759 Common accB_1 acyl-CoA carboxylase 1, carboxyltransferase component (beta subunit) NP4250A 151 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 76801922 Common - probable stress response protein NP2560A 136 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 76802027 Common rbcL ribulose bisophosphate carboxylase NP2770A 67 COG1850 RbcL, Ribulose 1,5-bisphosphate carboxylase, large subunit Carbohydrate transport and metabolism 76801192 Common abc25p ABC-type transport system permease protein (probable substrate copper) 3 NP1080A 15 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 76803130 Common abc03p ABC-type transport system permease protein (probable substrate iron(III)) NP5004A 193 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 76802231 Nonpathogen - hypothetical protein NP3182A 3 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 76802637 Nonpathogen - homolog to coenzyme F420 hydrogenase NP4006A 22 COG1035 FrhB, Coenzyme F420-reducing hydrogenase, beta subunit Energy production and conversion 76800785 Common - modification methylase NP0260A 79 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 76800816 Nonpathogen - hypothetical protein NP0324A 1 COG4061 MtrC, Tetrahydromethanopterin S-methyltransferase, subunit C Coenzyme metabolism 76800946 Nonpathogen cdc6 cell division control protein 6 NP0588A 31 COG1474 CDC6, Cdc6-related protein, AAA superfamily ATPase DNA replication, recombination, and repair / Posttranslational modification, protein turnover, chaperones 76801242 Common - glycosyltransferase homolog NP1180A 53 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 76802215 Nonpathogen - homolog 3 to transducer protein NP3150A 3 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 76800976 Nonpathogen blp blp-like protein NP0648A 6 COG3427 COG3427, Uncharacterized conserved protein Function unknown 76803291 Nonpathogen - hypothetical protein NP5328A 5 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 76801014 Nonpathogen - hypothetical protein NP0724A 2 None None None 76801454 Common - homolog 1 to cytochrome c-type biogenesis protein NP1608A 16 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 76802199 Common cheC_2 taxis cluster protein CheC 2 NP3118A 20 COG1776 CheC, Chemotaxis protein CheC, inhibitor of MCP methylation Cell motility and secretion / Signal transduction mechanisms 76802876 Nonpathogen - hypothetical protein NP4486A 1 None None None 76802124 Nonpathogen cbaD cytochrome-ba3 oxidase , CbaD subunit NP2966A 3 None None None 76803211 Common dcd deoxycytidine triphosphate deaminase NP5166A 155 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 76803302 Nonpathogen - hypothetical protein NP5350A 1 None None None 76802111 Nonpathogen - hypothetical protein NP2940A 1 None None None 76802332 Common - probable cell surface glycoprotein NP3388A 4 None None None 76802407 Common tp17 major facilitator family transporter 7 (probable phosphoglycerate transporter) NP3538A 97 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 76800905 Nonpathogen - hypothetical protein NP0506A 1 COG4640 COG4640, Predicted membrane protein Function unknown 76801085 Nonpathogen - hypothetical protein NP0866A 1 None None None 76803186 Common lpl_1 lipoate-protein ligase 1 NP5116A 70 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 76802192 Nonpathogen - hypothetical protein NP3104A 4 None None None 76801474 Common - hypothetical protein NP1648A 5 COG3391 COG3391, Uncharacterized conserved protein Function unknown 76803105 Nonpathogen - hypothetical protein NP4950A 1 None None None 76801695 Common cheY response regulator CheY NP2102A 225 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 76801982 Common trxB_1 thioredoxin reductase NP2680A 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 76802297 Nonpathogen - hypothetical protein NP3316A 1 None None None 76803139 Nonpathogen - hypothetical protein NP5022A 2 None None None 76802435 Common - homolog 2 to lyase/ dioxygenase NP3594A 14 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 76801828 Common - integrase homolog NP2370A 9 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 76802518 Common qor_2 NADPH:quinone reductase 2 NP3766A 170 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 76802988 Nonpathogen - hypothetical protein NP4712A 1 None None None 76801516 Common pyrF orotidine-5'-phosphate decarboxylase NP1734A 66 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 76802282 Nonpathogen - hypothetical protein NP3286A 1 None None None 76802344 Nonpathogen - ubiD operon protein NP3412A 2 None None None 76802981 Nonpathogen - homolog to sensory rhodopsin I (nonfunctional) NP4698A 1 None None None 76803207 Common pmm_4 phosphohexomutase 4 (phosphoglucomutase , phosphomannomutase ) NP5158A 240 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 76802161 Common abc22p ABC-type transport system permease protein (probable substrates tungstate/sulfate) NP3042A 221 COG4662 TupA, ABC-type tungstate transport system, periplasmic component Coenzyme metabolism 76800902 Common tp14 major facilitator family transporter 4 (probable hexuronate transporter; probable sugar transporter) NP0500A 134 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 76802266 Nonpathogen - hypothetical protein NP3254A 1 None None None 76801426 Nonpathogen - hypothetical protein NP1552A 1 None None None 76800930 Common dsa branched-chain alpha-keto acid dehydrogenase subunit E2 NP0556A 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 76800963 Common - signal-transducing histidine kinase; PAS/PAC domain protein NP0622A 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76801009 Nonpathogen - homolog 2 to transducer protein NP0714A 6 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 76802294 Nonpathogen - hypothetical protein NP3310A 1 None None None 76801253 Common phfZ PhzF-like protein NP1202A 121 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 76802862 Nonpathogen - hypothetical protein NP4458A 1 None None None 76802947 Common - IS200-type transposase NP4630A 71 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 76801650 Common ureC urease subunit alpha NP2010A 96 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 76803087 Common cmk cytidylate kinase NP4914A 47 COG1102 Cmk, Cytidylate kinase Nucleotide transport and metabolism 76801970 Common - signal-transducing histidine kinase; PAS/PAC domain protein NP2656A 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76801391 Nonpathogen - hypothetical protein NP1480A 1 None None None 76803153 Nonpathogen - hypothetical protein NP5050A 1 None None None 76803051 Nonpathogen - hypothetical protein NP4842A 3 None None None 76800738 Common abc09a1 ABC-type transport system ATP-binding protein I (probable substrates branched-chain/neutral amino acids) 5 NP0166A 247 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 76801278 Common - predicted transporter NP1252A 134 COG2252 COG2252, Permeases General function prediction only 76802586 Nonpathogen - hypothetical protein NP3902A 1 None None None 76803007 Common tif5A translation initiation factor IF-5A NP4752A 37 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 76801223 Nonpathogen - hypothetical protein NP1142A 4 None None None 76801136 Nonpathogen - hypothetical protein NP0970A 2 None None None 76803083 Common tp29u2_2 Trk-type transport system (probable substrate potassium) 1, subunit 2.2 NP4906A 123 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 76802171 Common trpD_3 homolog to anthranilate phosphoribosyltransferase NP3062A 173 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 76801865 Nonpathogen - hypothetical protein NP2444A 4 None None None 76800989 Nonpathogen - probable transcription regulator NP0674A 14 COG1846 MarR, Transcriptional regulators Transcription 76802773 Common - short chain dehydrogenase NP4278A 217 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 76803247 Nonpathogen - hypothetical protein NP5238A 1 None None None 76800666 Nonpathogen - hypothetical protein NP0022A 5 None None None 76801296 Nonpathogen - hypothetical protein NP1290A 1 None None None 76801155 Common ths_1 thermosome subunit 1 (alpha subunit) NP1008A 245 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 76801493 Common - hydrolase (probable hydroxyacylglutathione hydrolase ) 4 NP1688A 67 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 76801782 Common - probable metalloprotease NP2278A 38 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 76801826 Nonpathogen - probable transcription regulator NP2366A 4 COG1695 COG1695, Predicted transcriptional regulators Transcription 76801045 Common rpiA ribose-5-phosphate epimerase NP0786A 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 76803048 Common mvaB_2 hydroxymethylglutaryl-CoA synthase 2 NP4836A 46 COG3425 PksG, 3-hydroxy-3-methylglutaryl CoA synthase Lipid metabolism 76800741 Common abc09p1 ABC-type transport system permease protein I (probable substrates branched-chain/neutral amino acids) 5 NP0172A 149 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 76801351 Common - iron-sulfur protein (probable glycolate oxidase iron-sulfur subunit) NP1400A 73 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 76801020 Nonpathogen cobT hypothetical protein NP0736A 31 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 76801244 Common msc_1 probable mechanosensitive channel NP1184A 195 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 76800743 Common - probable NAD(P)H nitroreductase NP0176A 142 COG0778 NfnB, Nitroreductase Energy production and conversion 76801399 Nonpathogen - hypothetical protein NP1498A 3 None None None 76802417 Nonpathogen - hypothetical protein NP3558A 1 None None None 76800760 Common - predicted mRNA 3'-end processing factor NP0210A 135 COG1782 COG1782, Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain General function prediction only 76800773 Nonpathogen - restriction system mrr homolog NP0236A 6 COG1715 Mrr, Restriction endonuclease Defense mechanisms 76802597 Common abc12a ABC-type transport system ATP-binding protein (probable substrate copper) 2 NP3924A 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 76802204 Common - hypothetical protein NP3128A 13 COG1361 COG1361, S-layer domain Cell envelope biogenesis, outer membrane 76801079 Common - DNA-directed DNA polymerase (family X) / ycdX protein homolog NP0854A 88 COG1796 POL4, DNA polymerase IV (family X) DNA replication, recombination, and repair 76803202 Common cinA_2 CinA-like domain protein 2 NP5148A 159 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 76800748 Nonpathogen rplX 50S ribosomal protein LX NP0186A 5 COG2157 RPL20A, Ribosomal protein L20A (L18A) Translation, ribosomal structure and biogenesis 76802500 Nonpathogen - hypothetical protein NP3730A 1 None None None 76801633 Common - hydrolase (probable hydroxyacylglutathione hydrolase ) 9 NP1974A 125 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 76802391 Nonpathogen - hypothetical protein NP3506A 25 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 76801274 Common narB_2 nitrate reductase 2, catalytic subunit NP1244A 181 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 76801025 Common abc27p ABC-type transport system permease protein NP0746A 143 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 76801627 Common fxsA FxsA NP1962A 49 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 76803237 Common - sugar epimerase/dehydratase homolog NP5218A 109 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 76801559 Common - hypothetical protein NP1822A 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 76801171 Common moaB_2 probable molybdenum cofactor biosynthesis protein B 2 NP1040A 112 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 76801339 Nonpathogen - predicted sterol carrier protein NP1376A 9 COG3255 COG3255, Putative sterol carrier protein Lipid metabolism 76801055 Common aroE shikimate 5-dehydrogenase NP0806A 221 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 76801564 Common tp51 transporter 51 (probable sodium/hydrogen, malic/sodium-lactate antiporter) NP1832A 42 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 76802547 Common - hypothetical protein NP3824A 33 COG3380 COG3380, Predicted NAD/FAD-dependent oxidoreductase General function prediction only 76802063 Nonpathogen rpoN DNA-directed RNA polymerase subunit N NP2842A 34 COG1644 RPB10, DNA-directed RNA polymerase, subunit N (RpoN/RPB10) Transcription 76801119 Nonpathogen - hypothetical protein NP0934A 1 None None None 76802242 Nonpathogen rps15p 30S ribosomal protein S15P NP3204A 34 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 76800967 Nonpathogen - hypothetical protein NP0630A 3 None None None 76802404 Common tp50 probable transporter 50 (probable substrate cadmium) NP3532A 18 COG4300 CadD, Predicted permease, cadmium resistance protein Inorganic ion transport and metabolism 76803037 Common moaB_1 molybdenum cofactor biosynthesis protein B 1 NP4814A 100 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 76800939 Nonpathogen - hypothetical protein NP0574A 3 None None None 76800841 Common aimE_3 probable amidase (aliphatic amidase) 3 NP0374A 200 COG0388 COG0388, Predicted amidohydrolase General function prediction only 76800656 Nonpathogen - hypothetical protein NP0002A 2 COG3440 COG3440, Predicted restriction endonuclease Defense mechanisms 76801908 Nonpathogen - hypothetical protein NP2532A 1 None None None 76801683 Nonpathogen - hypothetical protein NP2078A 2 None None None 76801760 Nonpathogen - hypothetical protein NP2234A 2 None None None 76803003 Nonpathogen hcp_2 halocyanin 2 NP4744A 3 COG3794 PetE, Plastocyanin Energy production and conversion 76802616 Nonpathogen - hypothetical protein NP3964A 31 COG1407 COG1407, Predicted ICC-like phosphoesterases General function prediction only 76802466 Nonpathogen rpl7ae 50S ribosomal protein L7Ae NP3660A 34 COG1358 RPL8A, Ribosomal protein HS6-type (S12/L30/L7a) Translation, ribosomal structure and biogenesis 76801112 Common hemB delta-aminolevulinic acid dehydratase NP0920A 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 76802853 Common cysS cysteine--tRNA ligase NP4440A 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 76803217 Common - hypothetical protein NP5178A 37 COG3439 COG3439, Uncharacterized conserved protein Function unknown 76802015 Nonpathogen - hypothetical protein NP2746A 35 COG1833 COG1833, Uncharacterized conserved protein Function unknown 76801332 Common tp15 major facilitator family transporter 5 (probable multidrug efflux transporter) NP1362A 69 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 76801903 Common - hypothetical protein NP2520A 108 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 76801166 Common atpA V-type ATP synthase subunit A NP1030A 247 COG1155 NtpA, Archaeal/vacuolar-type H+-ATPase subunit A Energy production and conversion 76803229 Nonpathogen - hypothetical protein NP5202A 1 None None None 76803224 Common ipp inorganic pyrophosphatase NP5192A 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 76802201 Common htr23 transducer protein htr23 NP3122A 124 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 76802275 Common - hypothetical protein NP3272A 49 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 76803070 Common rpl5p 50S ribosomal protein L5P NP4880A 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 76801929 Nonpathogen - hypothetical protein NP2574A 3 COG3216 COG3216, Uncharacterized protein conserved in bacteria Function unknown 76802456 Common htr8 transducer protein htr8 NP3638A 133 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 76801655 Common ureF urease accessory protein NP2020A 24 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 76802479 Nonpathogen ef1B elongation factor 1-beta NP3686A 30 COG2092 EFB1, Translation elongation factor EF-1beta Translation, ribosomal structure and biogenesis 76802984 Common tpsO predicted tryptophan-rich sensory protein NP4704A 59 COG3476 COG3476, Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) Signal transduction mechanisms 76801549 Common - IS1341-type transposase NP1802A 58 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 76800712 Common rpoA1 DNA-directed RNA polymerase subunit alpha NP0114A 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 76801598 Common - probable dehydrogenase/ reductase 5 NP1900A 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 76802707 Common cheW purine-binding taxis protein NP4146A 115 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 76802482 Common ferB ferredoxin II NP3692A 39 COG1146 COG1146, Ferredoxin Energy production and conversion 76802034 Nonpathogen - hypothetical protein NP2784A 4 None None None 76803147 Common pan_1 proteasome-activating nucleotidase NP5038A 249 COG1222 RPT1, ATP-dependent 26S proteasome regulatory subunit Posttranslational modification, protein turnover, chaperones 76801325 Common tatC_1 sec-independent protein translocase component TatC 1 NP1348A 200 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 76801576 Common - IS1341-type transposase NP1856A 59 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 76803077 Common rps5p 30S ribosomal protein S5P NP4894A 248 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 76802715 Nonpathogen rpoL DNA-directed RNA polymerase subunit L NP4162A 15 COG1761 RPB11, DNA-directed RNA polymerase, subunit L Transcription 76801838 Nonpathogen - hypothetical protein NP2390A 33 COG1258 COG1258, Predicted pseudouridylate synthase Translation, ribosomal structure and biogenesis 76801098 Common - hypothetical protein NP0892A 205 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 76800707 Common lpdA dihydrolipoamide dehydrogenase NP0104A 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 76803210 Nonpathogen - hypothetical protein NP5164A 27 COG2108 COG2108, Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme General function prediction only 76801671 Common - probable ferredoxin-NAD+ reductase 1 NP2052A 225 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 76802750 Common bioF 8-amino-7-oxononanoate synthase NP4232A 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 76803170 Common tif2g translation initiation factor IF-2 subunit gamma NP5084A 249 COG5257 GCD11, Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase) Translation, ribosomal structure and biogenesis 76801230 Common - GlpG-like protein NP1156A 154 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 76801148 Common - hypothetical protein NP0994A 56 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 76800846 Common graD_7 probable sugar nucleotidyltransferase NP0384A 208 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 76802993 Common - hypothetical protein NP4724A 11 None None None 76800695 Nonpathogen - hypothetical protein NP0080A 1 None None None 76801831 Common - hypothetical protein NP2376A 128 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 76800951 Nonpathogen - hypothetical protein NP0598A 4 None None None 76801348 Common abc21u ABC-type transport system operon protein (predicted ABC-type transport system substrate-binding protein) NP1394A 94 COG1268 BioY, Uncharacterized conserved protein General function prediction only 76801216 Nonpathogen - hypothetical protein NP1128A 12 COG3398 COG3398, Uncharacterized protein conserved in archaea Function unknown 76801706 Nonpathogen - hypothetical protein NP2124A 1 None None None 76800868 Nonpathogen - hypothetical protein NP0432A 3 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 76801744 Common ilvN acetolactate synthase , small subunit NP2200A 192 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 76802439 Common tp41_1 Kef-type transport system 2 (probable substrate potassium), subunit 1 NP3602A 186 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 76800733 Nonpathogen - hypothetical protein NP0156A 3 None None None 76800767 Nonpathogen tp48_1 transport system 48 (probable substrate zinc), subunit 1 NP0224A 17 COG1824 COG1824, Permease, similar to cation transporters Inorganic ion transport and metabolism 76801040 Common - hypothetical protein NP0776A 85 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 76800958 Nonpathogen pfdB prefoldin beta subunit NP0612A 31 COG1382 GimC, Prefoldin, chaperonin cofactor Posttranslational modification, protein turnover, chaperones 76803156 Common phaA pH adaptation potassium efflux system protein A; sodium/hydrogen antiporter subunit NP5056A 203 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 76802208 Nonpathogen - hypothetical protein NP3136A 13 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 76801954 Common tp54_2 predicted TRAP-type transport system permease protein NP2624A 67 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 76800971 Nonpathogen - hypothetical protein NP0638A 1 None None None 76802819 Common - dehydrogenase/ reductase 3 NP4370A 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 76802666 Common - repair DNA N-glycosylase / DNA-(apurinic or apyrimidinic site) lyase NP4064A 236 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 76802964 Nonpathogen - sugar metabolism cluster protein NP4664A 1 None None None 76801263 Common topA DNA topoisomerase I NP1222A 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 76802705 Nonpathogen gch3 GTP cyclohydrolase III NP4142A 16 COG2429 COG2429, Uncharacterized conserved protein Function unknown 76802081 Common - transcription regulator NP2878A 112 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 76803177 Nonpathogen - hypothetical protein NP5098A 2 None None None 76801022 Common - hypothetical protein NP0740A 8 None None None 76802362 Common - hypothetical protein NP3448A 68 COG2718 COG2718, Uncharacterized conserved protein Function unknown 76802871 Common msc_7 probable mechanosensitive channel NP4476A 213 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 76801978 Common ribG hypothetical protein NP2672A 192 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 76801059 Nonpathogen nusG transcription antitermination protein NusG NP0814A 33 COG0250 NusG, Transcription antiterminator Transcription 76801721 Nonpathogen flaCE flagella accessory protein FlaCE NP2154A 8 COG3351 FlaD, Putative archaeal flagellar protein D/E Cell motility and secretion 76803076 Nonpathogen rpl18p 50S ribosomal protein L18P NP4892A 38 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 76803242 Common truD tRNA pseudouridine synthase D NP5228A 81 COG0585 COG0585, Uncharacterized conserved protein Function unknown 76803032 Common tp34 transporter 34 (probable phosphate/sulfate permease) NP4804A 56 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 76801306 Common trxA_1 thioredoxin NP1310A 229 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 76801101 Nonpathogen - helicase homolog NP0898A 13 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 76801886 Nonpathogen - hypothetical protein NP2486A 3 None None None 76800662 Common pepB_1 aminopeptidase (similar to leucyl aminopeptidase, aminopeptidase T) 1 NP0014A 37 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 76800974 Nonpathogen - hypothetical protein NP0644A 1 None None None 76802631 Common - hydrolase (BioH-like protein) NP3994A 134 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 76802687 Nonpathogen - hypothetical protein NP4106A 30 COG1675 TFA1, Transcription initiation factor IIE, alpha subunit Transcription 76802536 Common - homolog to ornithine cyclodeaminase NP3802A 96 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 76801936 Nonpathogen - hypothetical protein NP2588A 4 None None None 76801314 Common hemC hydroxymethylbilane synthase (porphobilinogen deaminase) NP1326A 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 76802676 Nonpathogen - hypothetical protein NP4084A 2 None None None 76802845 Nonpathogen - hypothetical protein NP4424A 4 None None None 76802492 Common - IS1341-type transposase NP3712A 70 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 76800723 Nonpathogen - predicted DNA binding protein NP0136A 9 COG3413 COG3413, Predicted DNA binding protein General function prediction only 76800887 Common hisE phosphoribosyl-ATP pyrophosphatase NP0470A 16 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 76800998 Nonpathogen - hypothetical protein NP0692A 2 COG3462 COG3462, Predicted membrane protein Function unknown 76801770 Common - hypothetical protein NP2254A 110 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 76801994 Nonpathogen - probable metalloprotease NP2704A 24 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 76801507 Nonpathogen - hypothetical protein NP1716A 1 None None None 76800944 Common - GTP-binding protein NP0584A 202 COG1084 COG1084, Predicted GTPase General function prediction only 76802001 Common - reductase (probable nitrate reductase / sulfite dehydrogenase ) 1 NP2718A 116 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 76801446 Common fbp fructose-1,6-bisphosphatase NP1592A 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 76802043 Common abc23a ABC-type transport system ATP-binding protein NP2802A 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 76802928 Common - hypothetical protein NP4590A 45 COG0730 COG0730, Predicted permeases General function prediction only 76801680 Common - hypothetical protein NP2070A 59 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 76801583 Common acd_9 acyl-CoA dehydrogenase 9 NP1870A 166 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 76802765 Common - homolog 1 to rad50 ATPase NP4262A 18 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 76800778 Nonpathogen rpl15R 50S ribosomal protein L15e NP0246A 34 COG1632 RPL15A, Ribosomal protein L15E Translation, ribosomal structure and biogenesis 76801208 Nonpathogen - conserved cobalamin operon protein NP1112A 4 COG1141 Fer, Ferredoxin Energy production and conversion 76800796 Common metA homoserine O-acetyltransferase NP0282A 133 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 76801462 Nonpathogen - hypothetical protein NP1624A 28 COG2047 COG2047, Uncharacterized protein (ATP-grasp superfamily) General function prediction only 76800680 Nonpathogen hcp_4 halocyanin 4 NP0050A 4 COG3794 PetE, Plastocyanin Energy production and conversion 76802600 Common abc13p ABC-type transport system permease protein (probable substrate sulfate) NP3930A 209 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 76802978 Common - halocyanin-like protein (copper-containing protein) 1 NP4692A 13 COG3794 PetE, Plastocyanin Energy production and conversion 76802472 Nonpathogen metE_2 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase , methionine synthase II, 2 NP3672A 9 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 76801443 Nonpathogen - hypothetical protein NP1586A 1 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 76801405 Nonpathogen - hypothetical protein NP1510A 1 None None None 76802019 Common hbd_2 3-hydroxyacyl-CoA dehydrogenase 2/ enoyl-CoA hydratase I 2 NP2754A 191 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 76802113 Common - probable helicase NP2944A 91 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 76801734 Common - homolog to predicted ATPase NP2180A 47 COG0433 COG0433, Predicted ATPase General function prediction only 76802069 Nonpathogen - hypothetical protein NP2854A 1 None None None 76803043 Common idiA isopentenyl-diphosphate delta-isomerase I NP4826A 39 COG1443 Idi, Isopentenyldiphosphate isomerase Lipid metabolism 76802541 Nonpathogen srp19 signal recognition particle 19K protein NP3812A 24 COG1400 SEC65, Signal recognition particle 19 kDa protein Intracellular trafficking and secretion 76802101 Common - predicted NAD-binding protein 1 (probable Kef-type transporter subunit) NP2920A 128 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 76802462 Nonpathogen - hypothetical protein NP3652A 4 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 76801419 Nonpathogen - pterin cluster protein (predicted DNA binding protein) NP1538A 9 COG3413 COG3413, Predicted DNA binding protein General function prediction only 76803265 Nonpathogen - hypothetical protein NP5276A 1 None None None 76801541 Nonpathogen - hypothetical protein NP1784A 1 None None None 76802974 Nonpathogen - hypothetical protein NP4684A 7 COG4190 COG4190, Predicted transcriptional regulator Transcription 76803027 Nonpathogen - hypothetical protein NP4794A 3 None None None 76801989 Common - hypothetical protein NP2694A 40 COG1881 COG1881, Phospholipid-binding protein General function prediction only 76800894 Nonpathogen sec11 signal peptidase I (signal sequence peptidase) NP0484A 13 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 76802351 Common abc08p1 ABC-type transport system permease protein (probable substrates branched-chain/neutral amino acids) I 4 NP3426A 165 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 76802317 Nonpathogen tyrA prephenate dehydrogenase NP3358A 4 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 76802049 Nonpathogen - hypothetical protein NP2814A 4 None None None 76801174 Nonpathogen - hypothetical protein NP1046A 2 COG2215 COG2215, ABC-type uncharacterized transport system, permease component General function prediction only 76801946 Common mvaB_1 hydroxymethylglutaryl-CoA synthase 1 NP2608A 37 COG3425 PksG, 3-hydroxy-3-methylglutaryl CoA synthase Lipid metabolism 76801538 Common abc04a ABC-type transport system ATP-binding protein (probable substrates glutamine/glutamate/polar amino acids) NP1778A 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 76801037 Common - hypothetical protein NP0770A 14 COG0546 Gph, Predicted phosphatases General function prediction only 76801439 Common - hypothetical protein NP1578A 5 None None None 76802810 Nonpathogen - hypothetical protein NP4352A 1 None None None 76802384 Nonpathogen - hypothetical protein NP3492A 1 None None None 76802115 Common - hypothetical protein NP2948A 4 None None None 76802695 Common - homolog 4 to S-adenosylmethionine-dependent methyltransferase 3 NP4122A 59 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 76802120 Nonpathogen - hypothetical protein NP2958A 5 None None None 76802963 Common galE_1 nucleoside-diphosphate-sugar epimerase 1 (probable UDP-glucose 4-epimerase ) NP4662A 232 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 76801371 Common moeA_1 molybdenum cofactor biosynthesis protein MoeA 1 NP1440A 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 76802094 Nonpathogen - hypothetical protein NP2904A 6 None None None 76803127 Common hemH phosphoribosylaminoimidazole-succinocarboxamide synthase NP4996A 11 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 76800756 Nonpathogen recJ single-stranded-DNA-specific exonuclease NP0202A 26 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 76802917 Common ferA_2 ferredoxin I 2 NP4568A 62 COG0633 Fdx, Ferredoxin Energy production and conversion 76801894 Nonpathogen - hypothetical protein NP2502A 2 None None None 76802659 Common acd_10 acyl-CoA dehydrogenase 10 NP4050A 161 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 76801414 Nonpathogen - hypothetical protein NP1528A 16 COG3388 COG3388, Uncharacterized protein conserved in archaea Function unknown 76802078 Common - probable protein acetyltransferase NP2872A 63 COG1243 ELP3, Histone acetyltransferase Transcription / Chromatin structure and dynamics 76801913 Common oxdhA_2 probable 2-oxoacid dehydrogenase E1 component, alpha subunit 2 NP2542A 159 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 76802905 Common uppS_2 di-trans,poly-cis-decaprenylcistransferase 2; (Z)-prenyl diphosphate synthase 2 NP4544A 194 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 76802393 Common udp_1 uridine phosphorylase 1 NP3510A 101 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 76802359 Nonpathogen - hypothetical protein NP3442A 4 None None None 76801624 Nonpathogen - hypothetical protein NP1956A 12 COG3430 COG3430, Uncharacterized protein conserved in archaea Function unknown 76802180 Common guaB_2 IMP dehydrogenase 2; GMP reductase NP3080A 233 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 76800880 Nonpathogen - hypothetical protein NP0456A 1 None None None 76801518 Common - hypothetical protein NP1738A 51 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 76802910 Nonpathogen - hypothetical protein NP4554A 4 None None None 76802058 Common rps11p 30S ribosomal protein S11P NP2832A 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 76802894 Nonpathogen - hypothetical protein NP4522A 3 None None None 76800727 Common - signal-transducing histidine kinase; probable PAS/PAC domain protein NP0144A 219 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 76803204 Nonpathogen - hypothetical protein NP5152A 4 None None None 76802822 Common glnA_2 glutamate--ammonia ligase 2 NP4376A 229 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 76802738 Common surE acid phosphatase NP4208A 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 76802304 Nonpathogen - hypothetical protein NP3330A 2 COG3413 COG3413, Predicted DNA binding protein General function prediction only 76802252 Nonpathogen - hypothetical protein NP3224A 21 COG1107 COG1107, Archaea-specific RecJ-like exonuclease, contains DnaJ-type Zn finger domain DNA replication, recombination, and repair 76801251 Common abc26a ABC-type transport system ATP-binding protein (probable substrate copper) 4 NP1198A 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 76802411 Nonpathogen - hypothetical protein NP3546A 1 None None None 76802898 Common - hypothetical protein NP4530A 16 COG4347 COG4347, Predicted membrane protein Function unknown 76802481 Common - hypothetical protein NP3690A 48 COG1444 COG1444, Predicted P-loop ATPase fused to an acetyltransferase General function prediction only 76801645 Common abc10p2 ABC-type transport system permease protein II (probable substrates urea/short chain-amides) NP2000A 135 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 76802771 Common - homolog 1 to lysine biosynthesis regulator/ribosomal protein S6 modification enzyme (glutaminyl transferase) NP4274A 105 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 76801043 Nonpathogen - hypothetical protein NP0782A 15 COG1361 COG1361, S-layer domain Cell envelope biogenesis, outer membrane 76802939 Nonpathogen - hypothetical protein NP4612A 3 None None None 76801176 Common tif2Ba_2 translation initiation factor 2B alpha chain II NP1050A 97 COG1184 GCD2, Translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 76802588 Common tp27 transporter 27 (probable substrates citrate/succinate, 2-oxoglutarate/malate) NP3906A 117 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 76802122 Common cbaA cytochrome-ba3 oxidase , subunit I NP2962A 172 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 76802589 Common - IS1341-type transposase NP3908A 31 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 76800813 Common aup histone deacetylase NP0318A 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 76802614 Nonpathogen - replication factor A NP3960A 25 COG1599 RFA1, Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins DNA replication, recombination, and repair 76802378 Common top6A DNA topoisomerase VI subunit A NP3480A 34 COG1697 COG1697, DNA topoisomerase VI, subunit A DNA replication, recombination, and repair 76803000 Common - hypothetical protein NP4738A 20 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 76801765 Common - probable glycosyltransferase NP2244A 172 COG0392 COG0392, Predicted integral membrane protein Function unknown 76801221 Nonpathogen - hypothetical protein NP1138A 1 None None None 76800787 Common atpD V-type ATP synthase subunit D NP0264A 36 COG1394 NtpD, Archaeal/vacuolar-type H+-ATPase subunit D Energy production and conversion 76802133 Common - homolog 2 to phosphatidylglycerophosphatase NP2984A 6 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 76802029 Common pho2 probable sugar phosphatase NP2774A 104 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 76800808 Common - sugar epimerase/dehydratase homolog NP0308A 83 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 76800689 Nonpathogen - hypothetical protein NP0068A 2 None None None 76801240 Nonpathogen - probable transcription regulator NP1176A 14 COG1846 MarR, Transcriptional regulators Transcription 76802177 Common tp23 transporter 23 (drug/metabolite family transporter 1) NP3074A 8 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 76801457 Nonpathogen rpl44e 50S ribosomal protein L44e NP1614A 30 COG1631 RPL42A, Ribosomal protein L44E Translation, ribosomal structure and biogenesis 76803161 Common nrdB_2 probable ribonucleoside-diphosphate reductase , beta subunit 2 NP5066A 8 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 76801718 Nonpathogen - hypothetical protein NP2148A 1 None None None 76801960 Common tp46 transporter 46 (probable substrate zinc) NP2636A 28 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 76801600 Common ilvB_2 thiamine pyrophosphate-requiring enzyme (Acetolactate synthase 2, large subunit 2; benzoylformate decarboxylase ) NP1904A 219 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 76802661 Common thiE thiamine-phosphate pyrophosphorylase NP4054A 202 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 76801965 Nonpathogen - hypothetical protein NP2646A 3 None None None 76801146 Nonpathogen cdsA hypothetical protein NP0990A 32 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 76801554 Nonpathogen - hypothetical protein NP1812A 1 None None None 76800961 Nonpathogen - hypothetical protein NP0618A 16 COG3356 COG3356, Predicted membrane protein Function unknown 76801293 Nonpathogen - homolog to stress response protein NP1284A 3 None None None 76801608 Common - glycosyl/glycerophosphate transferase (probable polyglycerol phosphate polymerase homolog) NP1920A 32 COG1887 TagB, Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC Cell envelope biogenesis, outer membrane 76802198 Common cysK_2 cysteine synthase 2 NP3116A 222 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 76802820 Common tp05 stress response protein/ transporter 5 (probable substrates cationic amino acids) NP4372A 173 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 76803250 Common tpc RNA 3'-terminal-phosphate cyclase NP5244A 47 COG0430 RCL1, RNA 3'-terminal phosphate cyclase RNA processing and modification 76801052 Common trpG_2 anthranilate synthase , component II 2 NP0800A 235 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 76801367 Common aor_2 aldehyde ferredoxin oxidoreductase 2 NP1432A 57 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 76802020 Common - hypothetical protein NP2756A 37 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 76802522 Common gatE glutamyl-tRNA(Gln) amidotransferase subunit E NP3774A 206 COG2511 GatE, Archaeal Glu-tRNAGln amidotransferase subunit E (contains GAD domain) Translation, ribosomal structure and biogenesis 76801097 Common - homolog to PhnP-like protein NP0890A 7 COG1237 COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II General function prediction only 76801459 Common tif2a translation initiation factor IF-2 subunit alpha NP1618A 174 COG1093 SUI2, Translation initiation factor 2, alpha subunit (eIF-2alpha) Translation, ribosomal structure and biogenesis 76801727 Nonpathogen - conserved che operon protein NP2166A 13 COG2469 COG2469, Uncharacterized conserved protein Function unknown 76801562 Nonpathogen - hypothetical protein NP1828A 2 None None None 76801190 Common ilvA threonine ammonia-lyase NP1076A 225 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 76801381 Nonpathogen - hypothetical protein NP1460A 2 COG1522 Lrp, Transcriptional regulators Transcription 76802577 Common - hypothetical protein NP3884A 14 COG1637 COG1637, Predicted nuclease of the RecB family DNA replication, recombination, and repair 76803284 Nonpathogen - hypothetical protein NP5314A 1 None None None 76801465 Common crtI_3 phytoene dehydrogenase 3 (phytoene desaturase) NP1630A 20 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 76800996 Nonpathogen - hypothetical protein NP0688A 2 None None None 76801271 Common - probable ribosomal RNA methyltransferase NP1238A 152 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 76801452 Nonpathogen - hypothetical protein NP1604A 6 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 76800858 Nonpathogen - hypothetical protein NP0408A 20 COG2098 COG2098, Uncharacterized protein conserved in archaea Function unknown 76802552 Nonpathogen - hypothetical protein NP3834A 4 None None None 76803060 Common rpl2p 50S ribosomal protein L2P NP4860A 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 76801039 Nonpathogen - archaemetzincin-like protein NP0774A 30 COG1913 COG1913, Predicted Zn-dependent proteases General function prediction only 76801691 Nonpathogen flaF fla cluster protein FlaF NP2094A 3 COG3353 FlaF, Putative archaeal flagellar protein F Cell motility and secretion 76803117 Nonpathogen - hypothetical protein NP4976A 6 None None None 76801811 Nonpathogen - hypothetical protein NP2336A 1 None None None 76802807 Common - hypothetical protein NP4346A 41 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 76802170 Nonpathogen - hypothetical protein NP3060A 2 None None None 76801249 Common gadD glutamate decarboxylase NP1194A 123 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 76801017 Common - signal-transducing histidine kinase NP0730A 179 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76802238 Common tp38 transporter 38 (probable substrates zinc/cadmium/cations) NP3196A 176 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 76802258 Nonpathogen - hypothetical protein NP3236A 2 None None None 76803067 Common rpl14p 50S ribosomal protein L14P NP4874A 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 76800677 Nonpathogen - hypothetical protein NP0044A 2 None None None 76801984 Nonpathogen - hypothetical protein NP2684A 4 None None None 76802875 Nonpathogen - hypothetical protein NP4484A 4 COG1945 COG1945, Uncharacterized conserved protein Function unknown 76803199 Nonpathogen - hypothetical protein NP5142A 1 None None None 76802603 Common - hypothetical protein NP3936A 14 COG3398 COG3398, Uncharacterized protein conserved in archaea Function unknown 76801664 Common abc29a ABC-type transport system ATP-binding protein NP2038A 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 76800934 Common mer3_2 ATP-dependent DNA helicase 2 NP0564A 150 COG1204 COG1204, Superfamily II helicase General function prediction only 76802442 Common - transcription regulator NP3608A 120 COG1414 IclR, Transcriptional regulator Transcription 76803106 Nonpathogen - hypothetical protein NP4952A 1 None None None 76801851 Common nadB L-aspartate oxidase , quinolinate synthetase subunit B NP2416A 219 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 76800953 Nonpathogen - hypothetical protein NP0602A 4 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 76801483 Common gbp5 translation-associated GTPase NP1668A 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 76802244 Nonpathogen - conserved rps operon protein NP3208A 3 None None None 76801614 Nonpathogen - hypothetical protein NP1932A 1 None None None 76803097 Nonpathogen - homolog 4 to rad50 ATPase NP4934A 3 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 76801032 Common abc01p_1 ABC-type transport system permease protein (probable substrates dipeptide/oligopeptide/nickel) 1 NP0760A 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 76801298 Common - probable dehydrogenase/ reductase 9 NP1294A 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 76802599 Common abc13s ABC-type transport system substrate-binding protein (probable substrate sulfate) NP3928A 21 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 76800762 Common - hypothetical protein NP0214A 10 COG5502 COG5502, Uncharacterized conserved protein Function unknown 76802783 Nonpathogen - hypothetical protein NP4298A 1 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 76802561 Nonpathogen - hypothetical protein NP3852A 3 None None None 76803293 Nonpathogen - hypothetical protein NP5332A 2 None None None 76801199 Common chlID magnesium chelatase (protoporphyrin IX magnesium-chelatase), fused subunits ChlI/ ChlD NP1094A 68 COG1239 ChlI, Mg-chelatase subunit ChlI Coenzyme metabolism 76800987 Common epf1 mRNA cleavage and polyadenylation specificity factor homolog NP0670A 150 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 76803278 Common cobD L-threonine-O-3-phosphate decarboxylase NP5302A 234 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 76803080 Common secY preprotein translocase subunit SecY NP4900A 194 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 76803249 Nonpathogen - hypothetical protein NP5242A 3 None None None 76802430 Common abc02a ABC-type transport system ATP-binding protein (probable substrates dipeptide/oligopeptide/nickel) II NP3584A 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 76803190 Common idiB_2 isopentenyl-diphosphate delta-isomerase II 2 NP5124A 114 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 76801841 Nonpathogen - hypothetical protein NP2396A 2 COG3428 COG3428, Predicted membrane protein Function unknown 76800657 Common - hypothetical protein NP0004A 35 COG1430 COG1430, Uncharacterized conserved protein Function unknown 76800684 Nonpathogen - hypothetical protein NP0058A 1 None None None 76800771 Common mutS_2 DNA mismatch repair protein NP0232A 202 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 76801762 Common - 3-dehydroquinate synthase NP2238A 28 COG1465 COG1465, Predicted alternative 3-dehydroquinate synthase Amino acid transport and metabolism 76801393 Common htpX_2 htpX protein homolog NP1484A 185 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 76801919 Nonpathogen - hypothetical protein NP2554A 1 None None None 76801495 Common serS seryl-tRNA synthetase NP1692A 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 76803268 Common - hypothetical protein NP5282A 5 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 76802328 Nonpathogen - hypothetical protein NP3380A 4 None None None 76800878 Common leuS leucyl-tRNA synthetase NP0452A 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 76802450 Common tp56 probable transport protein 56 (probable polysaccharide biosynthesis transport protein) NP3624A 34 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 76801528 Nonpathogen - hypothetical protein NP1758A 1 COG5524 COG5524, Bacteriorhodopsin General function prediction only 76800731 Nonpathogen - hypothetical protein NP0152A 3 None None None 76802321 Common - probable glycosyltransferase NP3366A 146 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 76801784 Nonpathogen rps19R 30S ribosomal protein S19e NP2282A 34 COG2238 RPS19A, Ribosomal protein S19E (S16A) Translation, ribosomal structure and biogenesis 76801789 Common nuoA NADH dehydrogenase-like complex, subunit A NP2292A 164 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 76801872 Nonpathogen - conserved cox cluster protein NP2458A 1 None None None 76802071 Common acdA acyl-CoA synthetase III (probable acetate--CoA ligase (ADP-forming) ) NP2858A 152 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 76801126 Nonpathogen - nifU protein C-terminal domain homolog NP0948A 9 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 76803046 Common htrII sensory rhodopsin II transducer NP4832A 155 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 76800746 Common ftsY signal recognition particle receptor SRalpha NP0182A 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 76801557 Common tpa08 transport ATPase 8 (probable substrate arsenite) NP1818A 88 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 76801068 Common tp49_6 pH adaptation potassium efflux system protein C; sodium/hydrogen antiporter subunit NP0832A 90 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 76802648 Nonpathogen - hypothetical protein NP4028A 1 None None None 76801992 Common act_2 acyl-CoA thioester hydrolase 2 NP2700A 138 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 76801157 Nonpathogen rpl39e 50S ribosomal protein L39e NP1012A 13 COG2167 RPL39, Ribosomal protein L39E Translation, ribosomal structure and biogenesis 76802268 Nonpathogen cdc6_4 cell division control protein cdc6 homolog NP3258A 31 COG1474 CDC6, Cdc6-related protein, AAA superfamily ATPase DNA replication, recombination, and repair / Posttranslational modification, protein turnover, chaperones 76802402 Nonpathogen - hypothetical protein NP3528A 15 COG1325 COG1325, Predicted exosome subunit Translation, ribosomal structure and biogenesis 76801027 Nonpathogen - hypothetical protein NP0750A 16 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 76802468 Nonpathogen rpl24R ribosomal protein L24.eR NP3664A 29 COG2075 RPL24A, Ribosomal protein L24E Translation, ribosomal structure and biogenesis 76801900 Common - hypothetical protein NP2514A 77 COG1469 COG1469, Uncharacterized conserved protein Function unknown 76802003 Nonpathogen - hypothetical protein NP2722A 16 COG1745 COG1745, Predicted metal-binding protein General function prediction only 76802842 Nonpathogen - hypothetical protein NP4418A 19 COG2117 COG2117, Predicted subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 76802152 Common speD_1 agmatinase 1 NP3022A 128 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 76802757 Nonpathogen - hypothetical protein NP4246A 1 COG5496 COG5496, Predicted thioesterase General function prediction only 76801685 Nonpathogen - hypothetical protein NP2082A 2 None None None 76800769 Nonpathogen - hypothetical protein NP0228A 4 None None None 76802459 Common abc24u ABC-type transport system operon protein (predicted membrane protein) NP3646A 5 COG4541 COG4541, Predicted membrane protein Function unknown 76800836 Nonpathogen rpoM_1 probable DNA-directed RNA polymerase subunit M 1 NP0364A 33 COG1594 RPB9, DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS Transcription 76802386 Nonpathogen - hypothetical protein NP3496A 1 None None None 76801472 Common mpcT transducer protein mpcT NP1644A 155 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 76801801 Common - hypothetical protein NP2316A 72 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 76800965 Common - signal-transducing histidine kinase; response regulator; PAS/PAC domain protein NP0626A 197 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76801113 Common tp39 transporter 39 (probable substrate ammonium) NP0922A 211 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 76802954 Nonpathogen - hypothetical protein NP4644A 3 None None None 76801704 Common - hypothetical protein NP2120A 90 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 76800758 Nonpathogen brp_1 brp-like protein 1 NP0206A 5 None None None 76800736 Nonpathogen - predicted DNA binding protein NP0162A 10 COG3413 COG3413, Predicted DNA binding protein General function prediction only 76801007 Common alaS alanyl-tRNA synthetase NP0710A 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 76802280 Nonpathogen - hypothetical protein NP3282A 1 None None None 76801666 Common ccmE cytochrome c-type biogenesis protein NP2042A 6 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 76802299 Nonpathogen - hypothetical protein NP3320A 1 None None None 76801697 Common cheD taxis cluster protein CheD NP2106A 64 COG1871 CheD, Chemotaxis protein; stimulates methylation of MCP proteins Cell motility and secretion / Signal transduction mechanisms 76802187 Nonpathogen - hypothetical protein NP3094A 1 None None None 76801791 Common nuoCD NADH dehydrogenase-like complex, subunit CD NP2296A 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 76803164 Nonpathogen rps27aR 30S ribosomal protein S27ae NP5072A 7 COG1998 RPS31, Ribosomal protein S27AE Translation, ribosomal structure and biogenesis 76801185 Common - hypothetical protein NP1066A 44 COG1041 COG1041, Predicted DNA modification methylase DNA replication, recombination, and repair 76800900 Nonpathogen - hypothetical protein NP0496A 1 None None None 76802945 Common - probable cell surface glycoprotein NP4624A 43 None None None 76801070 Common tp49_4 putative monovalent cation/H+ antiporter subunit B NP0836A 30 COG1563 COG1563, Predicted subunit of the Multisubunit Na+/H+ antiporter Inorganic ion transport and metabolism 76801061 Nonpathogen - hypothetical protein NP0818A 8 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 76801514 Nonpathogen - hypothetical protein NP1730A 4 None None None 76801123 Common apbA 2-dehydropantoate 2-reductase NP0942A 79 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 76802590 Common - IS200-type transposase NP3910A 62 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 76802461 Common acaB_7 acetyl-CoA C-acyltransferase 7 NP3650A 103 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 76801912 Common cyc unspecific monooxygenase (cytochrome P450) NP2540A 83 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 76802855 Nonpathogen - transcription regulator NP4444A 3 COG1695 COG1695, Predicted transcriptional regulators Transcription 76802915 Common - predicted electron-transferring-flavoprotein dehydrogenase 2 NP4564A 63 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 76800980 Common - probable stress response protein NP0656A 59 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 76802148 Nonpathogen - hypothetical protein NP3014A 2 None None None 76801639 Common abc14r_2 ABC transport system regulatory protein (probable substrate phosphate) 1.2 NP1986A 196 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 76801972 Nonpathogen - hypothetical protein NP2660A 1 None None None 76800751 Nonpathogen - hypothetical protein NP0192A 4 COG1295 Rbn, Predicted membrane protein Function unknown 76803209 Nonpathogen - hypothetical protein NP5162A 29 COG2237 COG2237, Predicted membrane protein Function unknown 76803151 Nonpathogen - hypothetical protein NP5046A 4 COG4194 COG4194, Predicted membrane protein General function prediction only 76803243 Nonpathogen - hypothetical protein NP5230A 8 COG4031 COG4031, Predicted metal-binding protein General function prediction only 76801088 Common pepB_2 aminopeptidase (similar to leucyl aminopeptidase, aminopeptidase T) 2 NP0872A 63 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 76801891 Nonpathogen - hypothetical protein NP2496A 2 None None None 76803253 Common argG argininosuccinate synthase NP5252A 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 76802511 Common - signal-transducing histidine kinase NP3752A 215 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76802693 Nonpathogen - hypothetical protein NP4118A 1 None None None 76800909 Nonpathogen - hypothetical protein NP0514A 3 None None None 76801821 Common mutH DNA mismatch repair protein homolog NP2356A 11 COG3066 MutH, DNA mismatch repair protein DNA replication, recombination, and repair 76801867 Common coxB_1 cytochrome-c-like terminal oxidase , subunit II 1 NP2448A 115 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 76801816 Nonpathogen - hypothetical protein NP2346A 1 None None None 76802839 Nonpathogen ribE riboflavin synthase beta chain (6,7-dimethyl-8-ribityllumazine synthase) NP4412A 35 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 76801591 Common - hypothetical protein NP1886A 44 COG2520 COG2520, Predicted methyltransferase General function prediction only 76802218 Nonpathogen - hypothetical protein NP3156A 1 COG3641 PfoR, Predicted membrane protein, putative toxin regulator General function prediction only 76801134 Common htpX_1 heat shock protein HtpX NP0964A 191 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 76800668 Common crcB_1 protein crcB homolog 1 NP0026A 11 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 76800674 Common msrA methionine sulfoxide reductase A NP0038A 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 76801213 Common cbiL cobalt-precorrin-2 C(20)-methyltransferase NP1122A 94 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 76801024 Common uvrB excinuclease ABC subunit B NP0744A 229 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 76802821 Common - monooxygenase (homolog to alkanesulfonate monooxygenase) 2 NP4374A 47 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 76801280 Common pyrE orotate phosphoribosyltransferase NP1256A 122 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 76801511 Common - hypothetical protein NP1724A 11 COG1556 COG1556, Uncharacterized conserved protein Function unknown 76801973 Nonpathogen - hypothetical protein NP2662A 4 COG1547 COG1547, Uncharacterized conserved protein Function unknown 76803254 Common argH argininosuccinate lyase NP5254A 216 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 76800915 Nonpathogen - hypothetical protein NP0526A 3 None None None 76800782 Common - probable glucose dehydrogenase 1, type B; probable L-sorbosone dehydrogenase 2 NP0254A 124 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 76800669 Common - response regulator NP0028A 201 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 76802828 Common - hypothetical protein NP4388A 73 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 76801031 Common abc01s ABC-type transport system periplasmic substrate-binding protein (probable substrates dipeptide/oligopeptide/nickel) 1 NP0758A 182 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 76802293 Nonpathogen - hypothetical protein NP3308A 1 None None None 76801091 Common radA DNA repair and recombination protein RadA NP0878A 35 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 76801915 Nonpathogen - hypothetical protein NP2546A 4 None None None 76803270 Nonpathogen - hypothetical protein NP5286A 1 None None None 76801226 Nonpathogen - hypothetical protein NP1148A 3 None None None 76801259 Common - conserved smc operon protein NP1214A 26 COG1354 COG1354, Uncharacterized conserved protein Function unknown 76802341 Nonpathogen - hypothetical protein NP3406A 22 COG1860 COG1860, Uncharacterized protein conserved in archaea Function unknown 76800671 Common fadA_6 probable enoyl-CoA hydratase I 6 NP0032A 147 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 76801780 Common moaE molybdopterin converting factor, large subunit NP2274A 152 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 76801139 Common - hypothetical protein NP0976A 41 COG2210 COG2210, Uncharacterized conserved protein Function unknown 76800906 Nonpathogen - hypothetical protein NP0508A 1 None None None 76802288 Nonpathogen - hypothetical protein NP3298A 1 None None None 76801250 Common ppsA phosphoenolpyruvate synthase NP1196A 236 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 76801669 Common abc29p2 ABC-type transport system permease protein 2 (heme exporter protein C) NP2048A 145 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 76803245 Nonpathogen rpoP DNA-directed RNA polymerase subunit P NP5234A 12 COG1996 RPC10, DNA-directed RNA polymerase, subunit RPC10 (contains C4-type Zn-finger) Transcription 76801690 Nonpathogen flaD flagella cluster protein FlaD NP2092A 1 None None None 76802504 Nonpathogen psmA proteasome subunit alpha NP3738A 34 COG0638 PRE1, 20S proteasome, alpha and beta subunits Posttranslational modification, protein turnover, chaperones 76801005 Common - IS1341-type transposase NP0706A 65 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 76802326 Nonpathogen - probable cell surface glycoprotein NP3376A 2 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 76801008 Nonpathogen - hypothetical protein NP0712A 1 None None None 76801424 Common - hypothetical protein NP1548A 7 None None None 76801818 Nonpathogen - hypothetical protein NP2350A 1 None None None 76802874 Nonpathogen - hypothetical protein NP4482A 4 None None None 76800981 Common - probable stress response protein NP0658A 65 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 76802470 Nonpathogen - hypothetical protein NP3668A 1 None None None 76802847 Nonpathogen - hypothetical protein NP4428A 1 None None None 76801785 Nonpathogen - conserved purK operon protein NP2284A 6 COG4745 COG4745, Predicted membrane-bound mannosyltransferase Posttranslational modification, protein turnover, chaperones 76802145 Common - hypothetical protein NP3008A 130 COG2096 COG2096, Uncharacterized conserved protein Function unknown 76803227 Nonpathogen - hypothetical protein NP5198A 22 COG3379 COG3379, Uncharacterized conserved protein Function unknown 76803280 Nonpathogen cobS cobalamin (5'-phosphate) synthase NP5306A 4 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 76801300 Nonpathogen - hypothetical protein NP1298A 4 COG3269 COG3269, Predicted RNA-binding protein, contains TRAM domain General function prediction only 76802509 Common - predicted sugar kinase NP3748A 185 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 76803314 Nonpathogen - hypothetical protein NP5374A 5 None None None 76800686 Common - hypothetical protein NP0062A 42 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 76800994 Nonpathogen - hypothetical protein NP0684A 1 None None None 76802408 Nonpathogen - hypothetical protein NP3540A 4 None None None 76802591 Nonpathogen - homolog 2 to cytochrome c-type biogenesis protein NP3912A 4 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 76800770 Nonpathogen - hypothetical protein NP0230A 1 None None None 76803287 Nonpathogen - hypothetical protein NP5320A 3 None None None 76800979 Common bat bacterioopsin activator NP0654A 130 COG3413 COG3413, Predicted DNA binding protein General function prediction only 76801497 Common - IS1341-type transposase NP1696A 66 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 76801860 Nonpathogen - hypothetical protein NP2434A 6 None None None 76800889 Nonpathogen - hypothetical protein NP0474A 2 None None None 76802926 Common ferA_3 stress response protein/ ferredoxin I 3 NP4586A 154 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 76800806 Common tef1a elongation factor 1-alpha NP0304A 249 COG5256 TEF1, Translation elongation factor EF-1alpha (GTPase) Translation, ribosomal structure and biogenesis 76801592 Nonpathogen - hypothetical protein NP1888A 1 None None None 76802396 Nonpathogen - homolog 2 to KaiC-like transcriptional regulator NP3516A 5 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 76801531 Nonpathogen - hypothetical protein NP1764A 1 None None None 76801769 Common - AAA-type ATPase NP2252A 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 76800875 Nonpathogen - homolog to DNA topoisomerase I NP0446A 9 COG0551 TopA, Zn-finger domain associated with topoisomerase type I DNA replication, recombination, and repair 76800969 Common - hypothetical protein NP0634A 75 COG1259 COG1259, Uncharacterized conserved protein Function unknown 76802427 Common abc02s ABC-type transport system periplasmic substrate-binding protein (probable substrates dipeptide/oligopeptide/nickel) 2 NP3578A 192 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 76803119 Nonpathogen - hypothetical protein NP4980A 1 None None None 76801856 Nonpathogen - hypothetical protein NP2426A 1 None None None 76802498 Nonpathogen rnp3 ribonuclease P protein component 3 NP3726A 20 COG1603 RPP1, RNase P/RNase MRP subunit p30 Translation, ribosomal structure and biogenesis 76801118 Nonpathogen - hypothetical protein NP0932A 1 None None None 76801966 Common - hypothetical protein NP2648A 40 COG0824 FcbC, Predicted thioesterase General function prediction only 76802958 Common graD_1 sugar nucleotidyltransferase (probable glucose-1-phosphate thymidylyltransferase ) 1 NP4652A 240 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 76801506 Common - IS1341-type transposase NP1714A 72 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 76801065 Common tp49_9 putative monovalent cation/H+ antiporter subunit D NP0826A 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 76801115 Common - hypothetical protein NP0926A 111 COG0400 COG0400, Predicted esterase General function prediction only 76802000 Common - response regulator NP2716A 218 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 76802612 Common - hypothetical protein NP3956A 59 COG3046 COG3046, Uncharacterized protein related to deoxyribodipyrimidine photolyase General function prediction only 76801396 Common dapB dihydrodipicolinate reductase NP1492A 218 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 76802544 Common btuD corrinoid ABC transporter ATPase NP3818A 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 76802995 Common abc20s ABC-type transport system periplasmic substrate-binding protein (probable substrates zinc/manganese/metal ions) 2 (probable adhesion lipoprotein) NP4728A 46 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 76801029 Nonpathogen - hypothetical protein NP0754A 5 COG2339 COG2339, Predicted membrane protein Function unknown 76803041 Nonpathogen tfbA_6 transcription initiation factor TFB 6 NP4822A 34 COG1405 SUA7, Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB Transcription 76801636 Common abc14p2 ABC-type transport system permease protein II (probable substrate phosphate) 1 NP1980A 225 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 76800817 Common cbs_2 CBS domain protein 2 NP0326A 73 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 76802178 Common pepQ aminopeptidase (high similarity to Xaa-Pro aminopeptidase ) NP3076A 242 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 76800943 Nonpathogen - hypothetical protein NP0582A 1 None None None 76801703 Common ubiB_2 probable ubiquinone biosynthesis transmembrane protein 2 NP2118A 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 76802998 Nonpathogen - probable cell surface glycoprotein NP4734A 3 None None None 76802080 Common hisD histidinol dehydrogenase NP2876A 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 76803021 Common - IS1341-type transposase NP4782A 75 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 76803009 Common tp02 amino acid transporter 2 NP4758A 143 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 76801295 Nonpathogen - hypothetical protein NP1288A 1 None None None 76801892 Nonpathogen - hypothetical protein NP2498A 2 None None None 76802153 Common - homolog to predicted electron-transferring-flavoprotein dehydrogenase NP3024A 8 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 76801196 Common cbiE cobalt-precorrin-6Y C(5)-methyltransferase NP1088A 28 COG2241 CobL, Precorrin-6B methylase 1 Coenzyme metabolism 76801853 Common - hypothetical protein NP2420A 114 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 76801357 Nonpathogen tp35 transporter 35 (probable phosphate/sulfate permease) NP1412A 5 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 76800844 Nonpathogen - hypothetical protein NP0380A 29 COG2237 COG2237, Predicted membrane protein Function unknown 76803061 Common rps19p 30S ribosomal protein S19P NP4862A 235 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 76801307 Common - predicted RIO-like serine/threonine protein kinase II NP1312A 66 COG1718 RIO1, Serine/threonine protein kinase involved in cell cycle control Signal transduction mechanisms / Cell division and chromosome partitioning 76801568 Nonpathogen - hypothetical protein NP1840A 2 None None None 76803154 Common - transcription regulator NP5052A 101 COG1522 Lrp, Transcriptional regulators Transcription 76801560 Nonpathogen - hypothetical protein NP1824A 2 None None None 76801924 Common - hypothetical protein NP2564A 105 COG2135 COG2135, Uncharacterized conserved protein Function unknown 76801416 Nonpathogen - pterin operon protein (predicted DNA binding protein) NP1532A 6 COG3413 COG3413, Predicted DNA binding protein General function prediction only 76802338 Nonpathogen - hypothetical protein NP3400A 3 COG1988 COG1988, Predicted membrane-bound metal-dependent hydrolases General function prediction only 76800882 Common - truncated IS1341-type transposase NP0460A 73 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 76801788 Common purE phosphoribosylaminoimidazole carboxylase , catalytic subunit NP2290A 227 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 76801696 Common cheC_1 taxis cluster protein CheC 1 NP2104A 29 COG1776 CheC, Chemotaxis protein CheC, inhibitor of MCP methylation Cell motility and secretion / Signal transduction mechanisms 76802222 Common trpB_1 tryptophan synthase subunit beta NP3164A 224 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 76801716 Common pgsA probable CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase NP2144A 52 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 76801901 Common - signal-transducing histidine kinase; probable PAS/PAC domain protein NP2516A 171 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76802246 Common htr31 transducer protein htr31 NP3212A 104 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 76803034 Nonpathogen - homolog to probable nitrate/nitrite transporter NP4808A 3 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 76803296 Nonpathogen - hypothetical protein NP5338A 1 None None None 76801478 Common purB adenylosuccinate lyase NP1658A 238 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 76802413 Nonpathogen - hypothetical protein NP3550A 1 None None None 76800933 Common lipA lipoyl synthase NP0562A 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 76802424 Common tif1_2 translation initiation factor aIF-1 II (SUI1 protein, bacterial-type IF3) NP3572A 60 COG0023 SUI1, Translation initiation factor 1 (eIF-1/SUI1) and related proteins Translation, ribosomal structure and biogenesis 76801795 Nonpathogen nuoJ1 NADH dehydrogenase subunit J NP2304A 4 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 76801743 Common ilvC ketol-acid reductoisomerase NP2198A 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 76801820 Common tnpR resolvase NP2354A 111 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 76800730 Nonpathogen - hypothetical protein NP0150A 2 None None None 76801211 Common cbiG cobalamin biosynthesis protein CbiG NP1118A 79 COG2073 CbiG, Cobalamin biosynthesis protein CbiG Coenzyme metabolism 76801723 Common flaI flagella biogenesis protein FlaI (probable flagellin secretion system protein FlaI) NP2158A 225 COG0630 VirB11, Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis Cell motility and secretion / Intracellular trafficking and secretion 76802165 Nonpathogen - hypothetical protein NP3050A 3 None None None 76801125 Common - probable arylsulfatase ; probable choline-sulfatase NP0946A 73 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 76801846 Common nolA_1 NADH dehydrogenase 32K chain homolog NP2406A 190 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 76803308 Nonpathogen - hypothetical protein NP5362A 3 None None None 76803197 Common - probable stress response protein NP5138A 110 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 76802129 Nonpathogen - homolog to stress response protein NP2976A 15 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 76803101 Nonpathogen - anaerobic dehydrogenase operon protein NP4942A 1 None None None 76802195 Nonpathogen - probable S-adenosylmethionine-dependent methyltransferase 2 NP3110A 5 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 76803215 Common thi1 putative thiazole biosynthetic enzyme NP5174A 31 COG1635 THI4, Flavoprotein involved in thiazole biosynthesis Coenzyme metabolism 76801985 Nonpathogen flaD flagella accessory proteins FlaD NP2686A 4 COG3351 FlaD, Putative archaeal flagellar protein D/E Cell motility and secretion 76802582 Common - integrase homolog NP3894A 10 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 76802346 Common ubiD_2 prenyl carboxy-lyase 2 (probable 3-octaprenyl-4-hydroxybenzoate carboxy-lyase ) NP3416A 7 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 76802233 Common cysA thiosulfate sulfurtransferase NP3186A 144 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 76802469 Common ndk nucleoside-diphosphate kinase NP3666A 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 76802106 Nonpathogen - hypothetical protein NP2930A 1 None None None 76802632 Nonpathogen - hypothetical protein NP3996A 1 None None None 76802260 Nonpathogen - hypothetical protein NP3240A 1 None None None 76801436 Common - hypothetical protein NP1572A 71 COG2391 COG2391, Predicted transporter component General function prediction only 76803255 Nonpathogen - arg cluster protein NP5256A 15 None None None 76802628 Common - hypothetical protein NP3988A 21 COG0456 RimI, Acetyltransferases General function prediction only 76800759 Nonpathogen - hypothetical protein NP0208A 2 None None None 76800789 Nonpathogen - hypothetical protein NP0268A 3 None None None 76802615 Nonpathogen - hypothetical protein NP3962A 15 COG3390 COG3390, Uncharacterized protein conserved in archaea Function unknown 76801316 Common hemD uroporphyrinogen-III synthase NP1330A 18 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 76802907 Common cbs_7 CBS domain protein 7 NP4548A 61 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 76801001 Nonpathogen - hypothetical protein NP0698A 4 None None None 76802273 Common - hypothetical protein NP3268A 5 None None None 76802556 Common - hypothetical protein NP3842A 24 COG4715 COG4715, Uncharacterized conserved protein Function unknown 76802281 Nonpathogen - hypothetical protein NP3284A 1 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 76801077 Nonpathogen - hypothetical protein NP0850A 4 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 76801899 Common ppnK_1 probable NAD(+) kinase 1 (inorganic polyphosphate/ATP-NAD kinase) NP2512A 238 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 76801318 Nonpathogen - homolog to CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase NP1334A 3 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 76802900 Common tp08 transporter 8 (probable sodium/proline symporter, sodium/pantothenate symporter 1) NP4534A 131 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 76803166 Nonpathogen - conserved rpo operon protein NP5076A 27 COG1909 COG1909, Uncharacterized protein conserved in archaea Function unknown 76802042 Nonpathogen abc23p_1 ABC-type transport system permease protein 1 NP2800A 8 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 76802748 Common tp42 nitrate/nitrite transporter NP4228A 95 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 76802746 Common nirA_1 ferredoxin--nitrite reductase 1 NP4224A 163 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 76800853 Nonpathogen - hypothetical protein NP0398A 3 None None None 76800737 Common acs_5 acyl-CoA synthetase I 5 NP0164A 222 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 76803137 Nonpathogen - hypothetical protein NP5018A 2 None None None 76802419 Common - predicted helicase NP3562A 176 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 76801360 Nonpathogen - peroxiredoxin homolog NP1418A 17 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 76801290 Common tp28 transporter 28 (probable substrates citrate/succinate, 2-oxoglutarate/malate) NP1278A 147 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 76801800 Common nuoN NADH dehydrogenase-like complex, subunit N NP2314A 210 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 76801140 Common sirA sirA protein homolog NP0978A 48 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 76800824 Nonpathogen - hypothetical protein NP0340A 32 COG2016 COG2016, Predicted RNA-binding protein (contains PUA domain) Translation, ribosomal structure and biogenesis 76801467 Common tp10 transporter 10 (probable threonine/homoserine/homoserine lactone efflux protein) NP1634A 11 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 76801350 Nonpathogen abc21p ABC-type transport system permease protein (probable substrate cobalt) NP1398A 3 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 76802040 Common abc23u ABC transport system cluster protein (predicted ABC-type transport system substrate-binding protein); predicted oxidoreductase 1 NP2796A 204 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 76802524 Common fumC fumarate hydratase NP3778A 216 COG0114 FumC, Fumarase Energy production and conversion 76802075 Common abc19p ABC-type transport system permease protein (probable substrates zinc/manganese/metal ions) 1 NP2866A 117 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 76802621 Common proC pyrroline-5-carboxylate reductase NP3974A 210 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 76801602 Common nos nitric-oxide synthase , oxygenase subunit NP1908A 11 COG4362 COG4362, Nitric oxide synthase, oxygenase domain Inorganic ion transport and metabolism / Amino acid transport and metabolism 76801198 Common cobN cobalt chelatase NP1092A 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 76802210 Common tpa03 transport ATPase 3 (probable substrates copper/metal cation) NP3140A 230 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 76802375 Common ligB DNA ligase (ATP) NP3474A 107 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 76801618 Common - hypothetical protein (nonfunctional, N-terminal part, interrupted by ISH) NP1940A 10 COG3475 COG3475, LPS biosynthesis protein Cell envelope biogenesis, outer membrane 76801162 Nonpathogen atpK H(+)-transporting two-sector ATPase subunit K.a (A-type ATP synthase) NP1022A 7 None None None 76800873 Common trpS tryptophanyl-tRNA synthetase NP0442A 149 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 76801455 Nonpathogen - hypothetical protein NP1610A 1 None None None 76801987 Common cutA probable divalent divalent cation tolerance protein NP2690A 69 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 76803019 Common tp44 transporter 44 (probable sodium/calcium exchanging protein) NP4778A 107 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 76800701 Common - hydrolase (probable hydroxyacylglutathione hydrolase ) 8 NP0092A 162 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 76802414 Common - predicted dehydrogenase NP3552A 226 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 76802722 Common psd phosphatidylserine decarboxylase NP4176A 91 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 76803171 Nonpathogen - hypothetical protein NP5086A 1 None None None 76801328 Common - hypothetical protein NP1354A 72 COG1738 COG1738, Uncharacterized conserved protein Function unknown 76803236 Nonpathogen - hypothetical protein NP5216A 4 None None None 76802092 Common - peroxiredoxin homolog NP2900A 221 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 76802719 Common - DNA N-glycosylase / DNA lyase NP4170A 118 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 76802985 Nonpathogen - hypothetical protein NP4706A 3 None None None 76801202 Nonpathogen cbiX_2 conserved cobalamin cluster protein CbiX 2 (probable ferredoxin-like iron-sulfur protein) NP1100A 3 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 76800690 Common - predicted iron-sulfur oxidoreductase NP0070A 36 COG0731 COG0731, Fe-S oxidoreductases Energy production and conversion 76801429 Nonpathogen - hypothetical protein NP1558A 1 None None None 76802422 Nonpathogen - homolog 3 to mannose-1-phosphate guanylyltransferase (GDP) NP3568A 8 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 76802960 Common graD_2 sugar nucleotidyltransferase (probable glucose-1-phosphate thymidylyltransferase ) 2 NP4656A 242 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 76802352 Common abc08p2 ABC-type transport system permease protein II (probable substrates branched-chain/neutral amino acids) 4 NP3428A 164 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 76803108 Nonpathogen - anaerobic dehydrogenase subunit NP4956A 3 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 76801238 Nonpathogen - hypothetical protein NP1172A 8 None None None 76802476 Nonpathogen - hypothetical protein NP3680A 33 COG1491 COG1491, Predicted RNA-binding protein Translation, ribosomal structure and biogenesis 76802343 Common - homolog 2 to rad50 ATPase NP3410A 71 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 76802576 Common - hypothetical protein NP3882A 84 COG4717 COG4717, Uncharacterized conserved protein Function unknown 76803183 Common - probable KaiC-like transcriptional regulator 3 NP5110A 74 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 76802251 Nonpathogen - hypothetical protein NP3222A 22 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 76801642 Common citB_2 aconitate hydratase NP1994A 222 COG1048 AcnA, Aconitase A Energy production and conversion 76801285 Common hisA 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase NP1268A 215 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 76801877 Nonpathogen - hypothetical protein NP2468A 3 None None None 76802652 Nonpathogen - hypothetical protein NP4036A 4 None None None 76803135 Nonpathogen - hypothetical protein NP5014A 2 COG5652 COG5652, Predicted integral membrane protein Function unknown 76802837 Nonpathogen - hypothetical protein NP4408A 1 None None None 76801377 Common dld_2 probable D-lactate dehydrogenase / iron-sulfur protein (probable glycolate oxidase iron-sulfur subunit) NP1452A 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 76803010 Nonpathogen - hypothetical protein NP4760A 5 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 76801400 Common abc31p_2 ABC-type transport system permease protein (probable Fe-S cluster assembly protein) 2 NP1500A 181 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 76802438 Common - probable stress response protein NP3600A 94 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 76801372 Common moeA_2 molybdenum cofactor biosynthesis protein MoeA 2/ periplasmic molybdate-binding domain NP1442A 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 76802082 Nonpathogen - hypothetical protein NP2880A 2 None None None 76802691 Nonpathogen - hypothetical protein NP4114A 3 None None None 76802916 Common - probable amidase NP4566A 219 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 76802924 Nonpathogen - hypothetical protein NP4582A 4 None None None 76802448 Common - hypothetical protein NP3620A 3 None None None 76802706 Nonpathogen - hypothetical protein NP4144A 4 None None None 76800735 Common - predicted ATPase (homolog 3 to type II/IV secretion system proteins TadA/VirB11) NP0160A 214 COG0630 VirB11, Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis Cell motility and secretion / Intracellular trafficking and secretion 76802790 Common purF amidophosphoribosyltransferase NP4312A 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 76802813 Common - IS1341-type transposase NP4358A 70 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 76802767 Common sdhB succinate dehydrogenase , subunit B (iron-sulfur protein) NP4266A 207 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 76802151 Common aldH_2 aldehyde dehydrogenase 2 NP3020A 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 76800884 Common - predicted glutamine amidotransferase NP0464A 85 COG0311 PDX2, Predicted glutamine amidotransferase involved in pyridoxine biosynthesis Coenzyme metabolism 76801952 Common acd_1 acyl-CoA dehydrogenase 1 NP2620A 162 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 76802880 Nonpathogen - hypothetical protein NP4494A 1 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 76802967 Common - sugar metabolism cluster protein NP4670A 11 COG4190 COG4190, Predicted transcriptional regulator Transcription 76802671 Nonpathogen - hypothetical protein NP4074A 31 COG1938 COG1938, Archaeal enzymes of ATP-grasp superfamily General function prediction only 76801809 Nonpathogen - hypothetical protein NP2332A 1 None None None 76801587 Nonpathogen - hypothetical protein NP1878A 1 None None None 76802452 Common msc_4 probable mechanosensitive channel NP3628A 220 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 76802733 Common maa_3 galactoside O-acetyltransferase 3; maltose O-acetyltransferase 3 NP4198A 143 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 76800790 Nonpathogen prf1 peptide chain release factor 1 NP0270A 34 COG1503 eRF1, Peptide chain release factor 1 (eRF1) Translation, ribosomal structure and biogenesis 76802800 Nonpathogen - hypothetical protein NP4332A 2 None None None 76802972 Common graD_4 probable sugar nucleotidyltransferase NP4680A 107 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 76802398 Common pyrI aspartate carbamoyltransferase regulatory subunit NP3520A 65 COG1781 PyrI, Aspartate carbamoyltransferase, regulatory subunit Nucleotide transport and metabolism 76801231 Common nfi endonuclease V NP1158A 73 COG1515 Nfi, Deoxyinosine 3'endonuclease (endonuclease V) DNA replication, recombination, and repair 76802209 Common - hypothetical protein NP3138A 9 COG2836 COG2836, Uncharacterized conserved protein Function unknown 76802955 Common - hypothetical protein NP4646A 39 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 76801822 Common - modification methylase NP2358A 81 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 76802884 Common hemA glutamyl-tRNA reductase NP4502A 178 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 76802760 Common accA_1 biotin carboxylase 1, acyl-CoA carboxylase , alpha subunit 1 NP4252A 228 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 76802031 Common - predicted amidase NP2778A 77 COG2366 COG2366, Protein related to penicillin acylase General function prediction only 76800705 Common abc30a ABC-type transport system ATP-binding protein (probable substrates macrolides/ lipoproteins) NP0100A 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 76800797 Common metY_1 O-acetylhomoserine aminocarboxypropyltransferase 1, methionine synthase NP0284A 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 76801534 Common - heme O oxidase N-terminal domain homolog NP1770A 6 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 76801503 Nonpathogen - hypothetical protein NP1708A 10 None None None 76802708 Common - hypothetical protein NP4148A 22 COG2322 COG2322, Predicted membrane protein Function unknown 76802656 Common porB pyruvate--ferredoxin oxidoreductase , beta subunit NP4044A 108 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 76801793 Common nuoI NADH dehydrogenase-like complex, subunit I NP2300A 187 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 76801540 Common rfcB replication factor C large subunit NP1782A 90 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 76801159 Nonpathogen tif6 translation initiation factor IF-6 NP1016A 33 COG1976 TIF6, Translation initiation factor 6 (eIF-6) Translation, ribosomal structure and biogenesis 76801409 Nonpathogen - conserved DNA repair operon protein (probable DNA repair exonuclease) NP1518A 32 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 76802388 Common gyrA DNA gyrase subunit A NP3500A 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 76800897 Nonpathogen - hypothetical protein NP0490A 8 COG1617 COG1617, Uncharacterized conserved protein Function unknown 76802290 Nonpathogen - hypothetical protein NP3302A 1 None None None 76801673 Nonpathogen - homolog to ADP-ribose pyrophosphatase , GDP-mannose mannosyl hydrolase NP2056A 2 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 76802432 Common tp58 compatible solute transporter (probable substrate choline/ glycine betaine) NP3588A 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 76802256 Common - halocyanin-like protein (copper-containing protein) 3 NP3232A 10 COG3794 PetE, Plastocyanin Energy production and conversion 76801189 Common - hypothetical protein NP1074A 20 COG2170 COG2170, Uncharacterized conserved protein Function unknown 76800866 Common pyrD dihydroorotate dehydrogenase 2 NP0428A 236 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 76801573 Common - signal-transducing histidine kinase NP1850A 197 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76800992 Nonpathogen hjc Holliday junction resolvase NP0680A 22 COG1591 COG1591, Holliday junction resolvase - archaeal type DNA replication, recombination, and repair 76802564 Nonpathogen - hypothetical protein NP3858A 1 None None None 76802011 Common menE O-succinylbenzoic acid--CoA ligase NP2738A 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 76802729 Nonpathogen - hypothetical protein NP4190A 9 COG1967 COG1967, Predicted membrane protein Function unknown 76802865 Common thrC_2 threonine synthase 2 NP4464A 160 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 76802168 Common ppiA peptidylprolyl isomerase NP3056A 197 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 76802537 Nonpathogen - hypothetical protein NP3804A 4 COG4742 COG4742, Predicted transcriptional regulator Transcription 76801169 Common - hypothetical protein NP1036A 128 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 76802550 Common fadA_8 probable enoyl-CoA hydratase I 8 NP3830A 177 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 76803092 Common act_1 acyl-CoA thioester hydrolase 1 NP4924A 136 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 76800717 Common rps7 30S ribosomal protein S7P NP0124A 211 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 76801732 Common htr21 transducer protein htr21 NP2176A 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 76800764 Common dnaK dnaK-type molecular chaperone hsp70 NP0218A 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 76802143 Common acd_6 acyl-CoA dehydrogenase 6 NP3004A 165 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 76801187 Nonpathogen - hypothetical protein NP1070A 1 None None None 76800972 Common - hypothetical protein NP0640A 3 None None None 76802516 Common - NAD-dependent protein deacetylase NP3762A 152 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 76801548 Common - probable cell surface glycoprotein NP1800A 17 COG1470 COG1470, Predicted membrane protein Function unknown 76801631 Common guaAb GMP synthase subunit B NP1970A 238 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 76801975 Common - homolog to copper ion binding protein NP2666A 19 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 76802368 Common acd_3 acyl-CoA dehydrogenase 3 NP3460A 156 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 76801480 Common purNH phosphoribosylglycinamide formyltransferase / phosphoribosylaminoimidazolecarboxamide formyltransferase NP1662A 221 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 76803014 Common - conserved crt cluster protein NP4768A 12 COG2324 COG2324, Predicted membrane protein Function unknown 76801833 Nonpathogen - hypothetical protein NP2380A 4 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 76801686 Nonpathogen - hypothetical protein NP2084A 1 None None None 76801569 Nonpathogen - hypothetical protein NP1842A 2 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 76800757 Common crtI_2 phytoene dehydrogenase 2 (phytoene desaturase) NP0204A 85 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 76801343 Common - thioredoxin reductase homolog NP1384A 66 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 76803053 Nonpathogen - hypothetical protein NP4846A 2 None None None 76802859 Common rpl1P 50S ribosomal protein L1P NP4452A 195 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 76803176 Nonpathogen tfbA_7 transcription initiation factor TFB 7 NP5096A 34 COG1405 SUA7, Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB Transcription 76801881 Nonpathogen - homolog 2 to mannose-1-phosphate guanylyltransferase (GDP) NP2476A 3 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 76802664 Nonpathogen - hypothetical protein NP4060A 25 COG2090 COG2090, Uncharacterized protein conserved in archaea Function unknown 76801616 Nonpathogen - hypothetical protein (nonfunctional, C-terminal part, interrupted by ISH) NP1936A 1 None None None 76801640 Common asd aspartate-semialdehyde dehydrogenase NP1988A 192 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 76802495 Nonpathogen stt3 oligosaccharyl transferase NP3720A 13 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 76801130 Common - homolog 6 to S-adenosylmethionine-dependent methyltransferase 3 NP0956A 159 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 76801884 Common - hypothetical protein NP2482A 39 COG3367 COG3367, Uncharacterized conserved protein Function unknown 76802735 Nonpathogen - hypothetical protein NP4202A 4 None None None 76801380 Nonpathogen - hypothetical protein NP1458A 4 None None None 76800664 Common pimT_1 protein-L-isoaspartate O-methyltransferase NP0018A 159 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 76800955 Common prsA ribose-phosphate pyrophosphokinase NP0606A 238 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 76802797 Nonpathogen tfbA_5 transcription initiation factor TFB 5 NP4326A 34 COG1405 SUA7, Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB Transcription 76802186 Common cyaB adenylate cyclase NP3092A 39 COG1437 CyaB, Adenylate cyclase, class 2 (thermophilic) Nucleotide transport and metabolism 76801268 Common korA oxoglutarate--ferredoxin oxidoreductase , alpha subunit NP1232A 113 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 76801758 Nonpathogen - homolog to rhomboid protein NP2230A 4 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 76801105 Common - conserved nad operon protein NP0906A 72 COG1912 COG1912, Uncharacterized conserved protein Function unknown 76800811 Nonpathogen rpa replication factor A NP0314A 30 COG1599 RFA1, Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins DNA replication, recombination, and repair 76801526 Common acd_11 acyl-CoA dehydrogenase 11 NP1754A 154 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 76801389 Nonpathogen - hexosyltransferase homolog 3 NP1476A 9 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 76802098 Nonpathogen - predicted ATPase (nonfunctional, N-terminal part, inframe stop codon) NP2914A 26 COG0630 VirB11, Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis Cell motility and secretion / Intracellular trafficking and secretion 76803146 Common ilvE_1 branched-chain amino acid aminotransferase 1 NP5036A 219 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 76800848 Common tif1_1 translation initiation factor Sui1 NP0388A 54 COG0023 SUI1, Translation initiation factor 1 (eIF-1/SUI1) and related proteins Translation, ribosomal structure and biogenesis 76802830 Nonpathogen - probable cell surface glycoprotein NP4392A 1 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 76802487 Common - probable dehydrogenase/ reductase 10 NP3702A 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 76802714 Nonpathogen - hypothetical protein NP4160A 2 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 76801228 Nonpathogen - hypothetical protein NP1152A 4 None None None 76803222 Common rnhA ribonuclease H I NP5188A 29 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 76802937 Nonpathogen - homolog to ABC-type transport system periplasmic substrate-binding protein NP4608A 2 COG3391 COG3391, Uncharacterized conserved protein Function unknown 76802605 Common purM phosphoribosylaminoimidazole synthetase NP3940A 232 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 76803111 Common fdhA_1 anaerobic dehydrogenase (probable formate dehydrogenase , probable dimethylsulfoxide reductase ), alpha subunit (reductase subunit) NP4962A 189 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 76802682 Common - hypothetical protein NP4096A 26 COG3199 COG3199, Uncharacterized conserved protein Function unknown 76800926 Nonpathogen - hypothetical protein NP0548A 4 None None None 76801215 Common - stomatin homolog NP1126A 222 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 76800799 Common valS valyl-tRNA synthetase NP0288A 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 76800792 Common serB phosphoserine phosphatase NP0274A 155 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 76802775 Nonpathogen - hypothetical protein NP4282A 1 None None None 76802642 Nonpathogen - hypothetical protein NP4016A 3 None None None 76802039 Nonpathogen - predicted DNA binding protein NP2794A 8 COG3413 COG3413, Predicted DNA binding protein General function prediction only 76803124 Nonpathogen - hypothetical protein NP4990A 4 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 76801741 Common leuC isopropylmalate isomerase large subunit NP2194A 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 76800920 Common mutL DNA mismatch repair protein MutL NP0536A 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 76802872 Common - hypothetical protein NP4478A 13 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 76801264 Common - geranylgeranylglyceryl phosphate synthase-like protein NP1224A 34 COG1646 COG1646, Predicted phosphate-binding enzymes, TIM-barrel fold General function prediction only 76801120 Common nifS cysteine desulfurase , class V aminotransferase NP0936A 240 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 76802951 Nonpathogen - probable transposase NP4638A 5 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 76800929 Nonpathogen pcn DNA polymerase sliding clamp NP0554A 34 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 76801553 Common cstA carbon starvation protein A NP1810A 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 76802406 Common - signal-transducing histidine kinase NP3536A 173 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76802163 Common abc22u ABC-type transport system operon protein NP3046A 7 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 76801499 Nonpathogen - hypothetical protein NP1700A 25 COG2042 COG2042, Uncharacterized conserved protein Function unknown 76803316 Common - homolog to hydrolase NP5378A 59 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 76803282 Nonpathogen - conserved cobalamine operon protein NP5310A 9 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 76803289 Common ftsZ_2 cell division protein FtsZ NP5324A 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 76801257 Common - IS1341-type transposase NP1210A 76 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 76801247 Nonpathogen - hypothetical protein NP1190A 1 None None None 76802429 Common abc02p_2 ABC-type transport system permease protein (probable substrates dipeptide/oligopeptide/nickel) 4 NP3582A 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 76800977 Nonpathogen brp_2 brp-like protein 2 NP0650A 6 None None None 76800688 Common argS arginine--tRNA ligase NP0066A 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 76802287 Nonpathogen - hypothetical protein NP3296A 1 None None None 76800948 Nonpathogen - hypothetical protein NP0592A 14 COG3365 COG3365, Uncharacterized protein conserved in archaea Function unknown 76802008 Nonpathogen - men cluster protein (homolog 4 to transducer protein) NP2732A 2 None None None 76801962 Nonpathogen - hypothetical protein NP2640A 1 None None None 76802902 Nonpathogen - DNA primase NP4538A 34 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 76801941 Common msc_3 probable mechanosensitive channel NP2598A 216 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 76803234 Nonpathogen - hypothetical protein NP5212A 3 None None None 76801205 Common - conserved cobalamin operon protein NP1106A 6 None None None 76800831 Nonpathogen nac nascent polypeptide-associated complex protein NP0354A 27 COG1308 EGD2, Transcription factor homologous to NACalpha-BTF3 Transcription 76801433 Nonpathogen - hypothetical protein NP1566A 2 None None None 76801177 Common - hypothetical protein NP1052A 25 COG0622 COG0622, Predicted phosphoesterase General function prediction only 76801858 Common icd isocitrate dehydrogenase (NADP+) NP2430A 222 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 76801277 Common glx_1 probable glutaredoxin NP1250A 16 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 76802068 Nonpathogen - predicted phosphomevalonate kinase NP2852A 22 COG1608 COG1608, Predicted archaeal kinase General function prediction only 76801594 Nonpathogen - probable stress response protein NP1892A 5 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 76801660 Common - hypothetical protein NP2030A 87 COG1078 COG1078, HD superfamily phosphohydrolases General function prediction only 76803205 Common hisI phosphoribosyl-AMP cyclohydrolase NP5154A 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 76801634 Nonpathogen abc14r_1 ABC transport system regulatory protein (probable substrate phosphate) 1.1 NP1976A 26 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 76802710 Common - hypothetical protein NP4152A 90 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 76801170 Common - hypothetical protein NP1038A 126 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 76801422 Nonpathogen - conserved pterin operon protein NP1544A 3 COG3460 COG3460, Uncharacterized enzyme of phenylacetate metabolism Secondary metabolites biosynthesis, transport, and catabolism 76800815 Nonpathogen - hypothetical protein NP0322A 1 COG1913 COG1913, Predicted Zn-dependent proteases General function prediction only 76803086 Nonpathogen - conserved adk/cmk cluster protein NP4912A 20 COG1422 COG1422, Predicted membrane protein Function unknown 76802521 Common - probable tRNA/rRNA methyltransferase NP3772A 156 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 76802827 Common hcpE_2 probable 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase 2; probable 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase 2 NP4386A 174 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 76803163 Common - O-sialoglycoprotein endopeptidase/protein kinase NP5070A 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 76800676 Common tp01_1 transporter system 1 (probable substrates cationic amino acids), subunit 1 NP0042A 159 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 76802594 Common abc11a ABC-type transport system ATP-binding protein (probable substrate copper) 1 NP3918A 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 76801701 Nonpathogen - hypothetical protein NP2114A 3 COG3398 COG3398, Uncharacterized protein conserved in archaea Function unknown 76802295 Nonpathogen - hypothetical protein NP3312A 1 None None None 76801160 Nonpathogen atpH H(+)-transporting two-sector ATPase subunit H.a (A-type ATP synthase) NP1018A 1 None None None 76800904 Common uvrA excinuclease ABC chain A NP0504A 238 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 76801033 Common abc01p_2 ABC-type transport system permease protein (probable substrates dipeptide/oligopeptide/nickel) 2 NP0762A 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 76800744 Common aimE_2 probable amidase (aliphatic amidase) 2 NP0178A 46 COG0388 COG0388, Predicted amidohydrolase General function prediction only 76803082 Common tp29u2_1 Trk-type transport system (probable substrate potassium) 1, subunit 2.1 NP4904A 119 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 76803113 Nonpathogen - hypothetical protein NP4966A 4 None None None 76801862 Common - 5-formyltetrahydrofolate cyclo-ligase NP2438A 27 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 76802220 Common fba_2 fructose-bisphosphate aldolase NP3160A 90 COG1830 FbaB, DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes Carbohydrate transport and metabolism 76801297 Nonpathogen - hypothetical protein NP1292A 4 None None None 76801390 Common folCP folylpolyglutamate synthase / dihydropteroate synthase NP1478A 230 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 76801282 Common adh alcohol dehydrogenase NP1260A 214 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 76802744 Nonpathogen - hypothetical protein NP4220A 2 None None None 76801066 Common tp49_8 putative monovalent cation/H+ antiporter subunit D NP0828A 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 76803002 Common - IS1341-type transposase NP4742A 38 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 76803239 Common - glycosyltransferase homolog NP5222A 33 None None None 76801003 Nonpathogen - hypothetical protein NP0702A 4 None None None 76801890 Nonpathogen - protein N-acetyltransferase homolog NP2494A 12 COG0456 RimI, Acetyltransferases General function prediction only 76801649 Common ureB urease subunit beta NP2008A 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 76801546 Common proS prolyl-tRNA synthetase NP1796A 239 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 76801224 Nonpathogen - probable transcription regulator NP1144A 12 COG4189 COG4189, Predicted transcriptional regulator Transcription 76802943 Nonpathogen - probable cell surface glycoprotein NP4620A 3 COG3889 COG3889, Predicted solute binding protein General function prediction only 76800775 Nonpathogen - hypothetical protein NP0240A 11 COG5530 COG5530, Predicted integral membrane protein Function unknown 76801127 Nonpathogen - hypothetical protein NP0950A 1 None None None 76802348 Common acaB_3 acetyl-CoA C-acyltransferase 3 NP3420A 96 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 76801273 Nonpathogen - hypothetical protein NP1242A 1 None None None 76801688 Nonpathogen flg_2 flagellin precursor 2 NP2088A 7 COG1681 FlaB, Archaeal flagellins Cell motility and secretion 76801692 Nonpathogen flaG_1 fla cluster protein FlaG 1 NP2096A 8 COG3354 FlaG, Putative archaeal flagellar protein G Cell motility and secretion 76802118 Common hyuA_1 N-methylhydantoinase (ATP-hydrolyzing) A 1 NP2954A 115 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 76803006 Common - predicted cell surface protein/ lipoprotein NP4750A 131 COG1520 COG1520, FOG: WD40-like repeat Function unknown 76802584 Nonpathogen - hypothetical protein NP3898A 1 None None None 76801453 Common trx_2 thioredoxin 2 NP1606A 9 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 76802401 Nonpathogen - hypothetical protein NP3526A 4 None None None 76801011 Common - hypothetical protein NP0718A 5 None None None 76803257 Common argC N-acetyl-gamma-glutamyl-phosphate reductase NP5260A 195 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 76802373 Nonpathogen - hypothetical protein NP3470A 1 None None None 76802909 Common csp1_3 probable cold shock protein NP4552A 159 COG1278 CspC, Cold shock proteins Transcription 76802585 Nonpathogen - integrase homolog NP3900A 11 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 76801626 Nonpathogen - hypothetical protein NP1960A 1 None None None 76801897 Common tgtA1 queuine/archaeosine tRNA-ribosyltransferase I NP2508A 227 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 76802236 Nonpathogen - hypothetical protein NP3192A 3 None None None 76802640 Nonpathogen - hypothetical protein NP4012A 2 None None None 76801075 Nonpathogen - hypothetical protein NP0846A 8 COG3370 COG3370, Uncharacterized protein conserved in archaea Function unknown 76801802 Common - CBS domain protein / probable chromosome partitioning protein NP2318A 154 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 76802235 Common map methionine aminopeptidase NP3190A 211 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 76801925 Nonpathogen - hypothetical protein NP2566A 1 None None None 76802756 Common citE citryl-CoA lyase (citrate lyase beta subunit; an ATP citrate synthase subunit) NP4244A 108 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 76800784 Common tpa02 transport ATPase 2 (probable substrates zinc/cadmium) NP0258A 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 76801450 Nonpathogen - halocyanin-like protein (copper-containing protein) 2 NP1600A 4 COG3794 PetE, Plastocyanin Energy production and conversion 76801093 Common ligA DNA ligase (NAD) NP0882A 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 76801907 Nonpathogen - truncated IS1341-type transposase NP2530A 3 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 76802626 Common - homolog 3 to lyase/ dioxygenase NP3984A 11 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 76800871 Common - parA domain ATP-binding protein NP0438A 182 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 76801355 Common upp uracil phosphoribosyltransferase NP1408A 164 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 76803181 Nonpathogen - ATP-dependent DNA helicase (intein-containing) NP5106A 35 COG1241 MCM2, Predicted ATPase involved in replication control, Cdc46/Mcm family DNA replication, recombination, and repair 76802278 Nonpathogen - hypothetical protein NP3278A 2 None None None 76802158 Nonpathogen - hypothetical protein NP3034A 2 None None None 76801604 Common - signal-transducing histidine kinase; probable GAF, PAS/PAC domain protein NP1912A 205 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76801918 Nonpathogen - hypothetical protein NP2552A 2 None None None 76801142 Common - hypothetical protein NP0982A 33 COG2391 COG2391, Predicted transporter component General function prediction only 76803273 Common - multidrug efflux protein norM homolog NP5292A 110 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 76803168 Common rpoE1 DNA-directed RNA polymerase subunit E' NP5080A 50 COG1095 RPB7, DNA-directed RNA polymerase, subunit E' Transcription 76801362 Common - hypothetical protein NP1422A 42 COG2346 COG2346, Truncated hemoglobins General function prediction only 76802271 Nonpathogen - hypothetical protein NP3264A 3 None None None 76801336 Nonpathogen - hypothetical protein NP1370A 4 None None None 76802086 Nonpathogen - hypothetical protein NP2888A 2 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 76801767 Nonpathogen - hypothetical protein NP2248A 4 None None None 76802229 Common - predicted NAD-binding protein 2 (probable Kef-type transporter subunit) NP3178A 139 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 76801968 Nonpathogen - hypothetical protein NP2652A 3 None None None 76801385 Common abc07p2 ABC-type transport system permease protein II (probable substrates branched-chain/neutral amino acids) 3 NP1468A 156 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 76802194 Nonpathogen - transmembrane protein (homolog 1 to type II secretion system proteins TadC) NP3108A 18 COG1955 FlaJ, Archaeal flagella assembly protein J Cell motility and secretion / Intracellular trafficking and secretion 76801234 Common tpa07 transport ATPase 7 (probable substrate arsenite) NP1164A 59 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 76802023 Nonpathogen - hypothetical protein NP2762A 10 COG2512 COG2512, Uncharacterized membrane-associated protein/domain Function unknown 76802526 Common thiI thiamine biosynthesis protein ThiI (ATP pyrophosphatase) NP3782A 94 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 76801369 Common - probable glycosyltransferase NP1436A 31 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 76801302 Common - nudix family protein NP1302A 128 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 76803036 Common - IS200-type transposase NP4812A 72 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 76802528 Nonpathogen - hypothetical protein NP3786A 1 None None None 76802176 Common - AAA-type ATPase (transitional ATPase homolog) NP3072A 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 76803023 Nonpathogen - hypothetical protein NP4786A 1 None None None 76801026 Common abc27a ABC-type transport system ATP-binding protein NP0748A 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 76800842 Nonpathogen - hypothetical protein NP0376A 4 COG3427 COG3427, Uncharacterized conserved protein Function unknown 76801289 Nonpathogen flaK probable preflagellin peptidase NP1276A 12 None None None 76801714 Common hisC histidinol-phosphate aminotransferase 1 NP2140A 230 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 76802127 Common tpa04 transport ATPase 4 (probable substrates copper/metal cation) NP2972A 230 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 76803306 Nonpathogen - hypothetical protein NP5358A 10 COG3430 COG3430, Uncharacterized protein conserved in archaea Function unknown 76801309 Common - hypothetical protein NP1316A 52 COG3608 COG3608, Predicted deacylase General function prediction only 76802931 Common gcvP1 glycine dehydrogenase subunit 1 NP4596A 172 COG0403 GcvP, Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain Amino acid transport and metabolism 76800804 Nonpathogen - predicted allosteric regulator of homoserine dehydrogenase NP0300A 18 COG2061 COG2061, ACT-domain-containing protein, predicted allosteric regulator of homoserine dehydrogenase Amino acid transport and metabolism 76801566 Nonpathogen - hypothetical protein NP1836A 4 None None None 76801048 Common - homolog to hydrolase NP0792A 31 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 76801815 Nonpathogen - hypothetical protein NP2344A 1 None None None 76802137 Nonpathogen - homolog to dolichol kinase NP2992A 6 COG0170 SEC59, Dolichol kinase Lipid metabolism 76802354 Common abc08a1 ABC-type transport system ATP-binding protein I (probable substrates branched-chain/neutral amino acids) 4 NP3432A 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 76800941 Common - hypothetical protein NP0578A 42 COG1808 COG1808, Predicted membrane protein Function unknown 76801611 Nonpathogen - hypothetical protein NP1926A 1 None None None 76802336 Nonpathogen - hypothetical protein NP3396A 1 None None None 76801471 Common htr34 transducer protein htr34 NP1642A 183 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 76802022 Common htr25 transducer protein htr25 NP2760A 162 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 76803063 Common rps3p 30S ribosomal protein S3P NP4866A 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 76802306 Nonpathogen - hypothetical protein NP3334A 1 None None None 76801486 Nonpathogen - hypothetical protein NP1674A 1 None None None 76803094 Nonpathogen - hypothetical protein NP4928A 1 None None None 76801855 Nonpathogen - hypothetical protein NP2424A 1 None None None 76801015 Common - dehydrogenase/ reductase 2 NP0726A 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 76802848 Common - homolog to citryl-CoA lyase NP4430A 40 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 76802566 Nonpathogen - hypothetical protein NP3862A 1 None None None 76803102 Common fdhC anaerobic dehydrogenase (probable formate dehydrogenase , probable dimethylsulfoxide reductase ), membrane anchor subunit NP4944A 44 COG5557 COG5557, Polysulphide reductase Energy production and conversion 76802650 Common - hydrolase (probable hydroxyacylglutathione hydrolase ) 7 NP4032A 212 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 76802786 Nonpathogen - hypothetical protein NP4304A 1 None None None 76800983 Nonpathogen - hypothetical protein NP0662A 1 None None None 76801790 Common nuoB NADH dehydrogenase-like complex, subunit B NP2294A 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 76803195 Nonpathogen - hypothetical protein NP5134A 2 COG4327 COG4327, Predicted membrane protein Function unknown 76801797 Common nuoK NADH dehydrogenase-like complex, subunit K NP2308A 31 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 76802673 Common - hydrolase / carboxypeptidase NP4078A 175 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 76802731 Common - hypothetical protein NP4194A 31 COG1624 COG1624, Uncharacterized conserved protein Function unknown 76802882 Common - nirG protein homolog / nirH protein homolog NP4498A 51 COG1522 Lrp, Transcriptional regulators Transcription 76801476 Nonpathogen - hypothetical protein NP1652A 1 None None None 76801931 Common agt_1 aminotransferase class V (Serine--pyruvate aminotransferase 1; Alanine--glyoxylate aminotransferase 1) NP2578A 171 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 76802324 Common - hypothetical protein NP3372A 68 COG2170 COG2170, Uncharacterized conserved protein Function unknown 76803025 Nonpathogen - hypothetical protein NP4790A 2 None None None 76802654 Common sod superoxide dismutase NP4040A 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 76803298 Nonpathogen - hypothetical protein NP5342A 1 COG1224 TIP49, DNA helicase TIP49, TBP-interacting protein Transcription 76802315 Nonpathogen - hypothetical protein NP3354A 3 COG5373 COG5373, Predicted membrane protein Function unknown 76802802 Nonpathogen - hypothetical protein NP4336A 4 None None None 76803040 Nonpathogen - hypothetical protein NP4820A 1 COG2079 PrpD, Uncharacterized protein involved in propionate catabolism General function prediction only 76801353 Nonpathogen - hypothetical protein NP1404A 21 COG2150 COG2150, Predicted regulator of amino acid metabolism, contains ACT domain General function prediction only 76801551 Common gdhA_1 glutamate dehydrogenase 1 NP1806A 178 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 76802065 Common eno phosphopyruvate hydratase NP2846A 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 76802850 Common nrdB_3 probable ribonucleoside-diphosphate reductase , beta subunit 3 NP4434A 8 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 76801824 Nonpathogen - hypothetical protein NP2362A 1 None None None 76801998 Common argK transport ATPase, component for probable LAO/AO transport systems NP2712A 99 COG1703 ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family Amino acid transport and metabolism 76801588 Nonpathogen - hypothetical protein NP1880A 2 None None None 76801200 Nonpathogen - cobalamin cluster protein NP1096A 2 None None None 76801536 Common abc04p1 ABC-type transport system permease protein I (probable substrates polar amino acids) NP1774A 173 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 76802886 Common carB carbamoyl phosphate synthase large subunit NP4506A 235 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 76801927 Nonpathogen - hypothetical protein NP2570A 2 None None None 76802334 Common - IS1341-type transposase NP3392A 74 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 76802363 Common - conserved prkA cluster protein NP3450A 71 COG2719 SpoVR, Uncharacterized conserved protein Function unknown 76802769 Common sdhC succinate dehydrogenase , subunit C (cytochrome b-556) NP4270A 18 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 76801194 Nonpathogen - hypothetical protein NP1084A 3 None None None 76803225 Nonpathogen - hypothetical protein NP5194A 1 None None None 76802455 Common csp1_1 probable cold shock protein NP3636A 42 COG1278 CspC, Cold shock proteins Transcription 76800837 Common tp12 major facilitator family transporter 2 (probable quinolone resistance protein) NP0366A 205 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 76801805 Common - hypothetical protein NP2324A 23 COG1901 COG1901, Uncharacterized conserved protein Function unknown 76801501 Common lpl_2 homolog to lipoate-protein ligase NP1704A 11 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 76802969 Common graD_3 sugar nucleotidyltransferase (probable glucose-1-phosphate thymidylyltransferase ) 7 NP4674A 239 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 76801321 Common - oxidoreductase (probable Zn-dependent dehydrogenase , threonine 3-dehydrogenase ) NP1340A 136 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 76802545 Nonpathogen - hypothetical protein NP3820A 1 COG1414 IclR, Transcriptional regulator Transcription 76800886 Common - conserved hisE operon protein NP0468A 75 COG1259 COG1259, Uncharacterized conserved protein Function unknown 76802834 Common tp45 transporter 45 (probable substrate zinc) NP4402A 81 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 76803261 Common argF ornithine carbamoyltransferase NP5268A 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 76802762 Common alkK_2 acyl-CoA synthetase , type II 2 (probable long-chain-fatty-acid--CoA ligase ) NP4256A 220 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 76802644 Nonpathogen - transmembrane protein (homolog 2 to type II secretion system proteins TadC) NP4020A 18 COG1955 FlaJ, Archaeal flagella assembly protein J Cell motility and secretion / Intracellular trafficking and secretion 76802241 Common tif2Ba_1 translation initiation factor IF-2B subunit delta NP3202A 132 COG1184 GCD2, Translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 76802371 Common - CBS domain protein NP3466A 109 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 76801748 Common thiC thiamine biosynthesis protein ThiC NP2210A 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 76801083 Common - signal-transducing histidine kinase; PAS/PAC domain protein NP0862A 211 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76802720 Common cysE serine O-acetyltransferase NP4172A 213 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 76802073 Common abc19s ABC-type transport system periplasmic substrate-binding protein (probable substrates zinc/manganese/metal ions) 1 (probable adhesion lipoprotein) NP2862A 118 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 76801375 Common trxA_2 thioredoxin NP1448A 26 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 76801150 Common - mandelate racemase homolog / muconate lactonizing enzyme homolog NP0998A 118 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 76800721 Common mdh_1 malic enzyme NP0132A 213 COG0281 SfcA, Malic enzyme Energy production and conversion 76802868 Nonpathogen ubiA prenyltransferase NP4470A 36 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 76801255 Common - hypothetical protein NP1206A 46 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 76802914 Common - probable sugar dehydrogenase NP4562A 194 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 76800826 Nonpathogen - hypothetical protein NP0344A 1 None None None 76802701 Common abc05p2 ABC-type transport system permease protein II (probable substrates branched-chain/neutral amino acids) 1 NP4134A 130 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 76801441 Common gdhA_2 glutamate dehydrogenase 2 NP1582A 175 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 76800692 Common ribB 3,4-dihydroxy-2-butanone 4-phosphate synthase NP0074A 176 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 76803096 Nonpathogen - homolog 1 to KaiC-like transcriptional regulator NP4932A 8 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 76802983 Common tp52 transporter 52 (probable sodium/hydrogen, malic/sodium-lactate antiporter) NP4702A 50 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 76802090 Nonpathogen - hypothetical protein NP2896A 3 None None None 76802712 Common - hypothetical protein NP4156A 10 COG2510 COG2510, Predicted membrane protein Function unknown 76802727 Nonpathogen - hypothetical protein NP4186A 2 None None None 76800703 Common srp54 signal recognition particle 54K protein NP0096A 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 76801652 Common ureG urease accessory protein NP2014A 149 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 76802156 Nonpathogen - hypothetical protein NP3030A 4 None None None 76802301 Nonpathogen - hypothetical protein NP3324A 1 None None None 76801523 Common abc17s ABC-type transport system periplasmic substrate-binding protein (probable substrate phosphonate) 1 NP1748A 69 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 76801842 Common cofG FO synthase subunit 1 NP2398A 45 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 76802815 Common tp55 transporter 55(probable sodium-dependent transporter) NP4362A 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 76801420 Nonpathogen - pterin cluster protein NP1540A 2 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 76802276 Common - hypothetical protein NP3274A 104 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 76801236 Common aspC aspartyl-tRNA synthetase NP1168A 249 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 76802055 Nonpathogen - hypothetical protein NP2826A 2 None None None 76801659 Common - hypothetical protein NP2028A 39 COG0391 COG0391, Uncharacterized conserved protein Function unknown 76802330 Common guaB_1 IMP dehydrogenase 1/ CBS domain protein NP3384A 243 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 76801370 Nonpathogen - hypothetical protein NP1438A 14 COG5427 COG5427, Uncharacterized membrane protein Function unknown 76803271 Nonpathogen - hypothetical protein NP5288A 3 COG3216 COG3216, Uncharacterized protein conserved in bacteria Function unknown 76802698 Nonpathogen - protein N-acetyltransferase homolog NP4128A 4 COG0456 RimI, Acetyltransferases General function prediction only 76801739 Common leuB 3-isopropylmalate dehydrogenase NP2190A 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 76801054 Nonpathogen - conserved aromatic amino acid cluster protein NP0804A 5 None None None 76801287 Common ferA_1 ferredoxin I 1 NP1272A 62 COG0633 Fdx, Ferredoxin Energy production and conversion 76802474 Common msc_5 probable mechanosensitive channel NP3676A 227 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 76802110 Common - hypothetical protein NP2938A 61 COG3246 COG3246, Uncharacterized conserved protein Function unknown 76801410 Nonpathogen - hypothetical protein NP1520A 1 None None None 76801434 Nonpathogen - hypothetical protein NP1568A 4 None None None 76802574 Common - probable ADP-ribosylglycohydrolase NP3878A 72 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 76800755 Common - homolog to acetylornithine deacetylase NP0200A 9 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 76802184 Nonpathogen - hypothetical protein NP3088A 1 None None None 76801756 Nonpathogen - hypothetical protein NP2226A 1 None None None 76803122 Nonpathogen - hypothetical protein NP4986A 30 COG1439 COG1439, Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module General function prediction only 76802777 Nonpathogen - predicted DNA binding protein NP4286A 10 COG3413 COG3413, Predicted DNA binding protein General function prediction only 76802795 Common hbd_3 3-hydroxyacyl-CoA dehydrogenase 3/ enoyl-CoA hydratase I 3 NP4322A 187 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 76801182 Nonpathogen - hypothetical protein NP1060A 1 None None None 76801266 Common glo_2 lyase / dioxygenase 2 (probable lactoylglutathione lyase , aromatic compounds dioxygenase ) NP1228A 88 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 76803200 Common - predicted helicase NP5144A 173 COG1202 COG1202, Superfamily II helicase, archaea-specific General function prediction only 76801261 Nonpathogen - conserved smc operon protein NP1218A 1 None None None 76802922 Common dhs putative deoxyhypusine synthase NP4578A 63 COG1899 DYS1, Deoxyhypusine synthase Posttranslational modification, protein turnover, chaperones 76802037 Nonpathogen - hypothetical protein NP2790A 1 None None None 76801730 Common cheA taxis sensor histidine kinase NP2172A 160 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 76800708 Common pheA2 prephenate dehydratase NP0106A 214 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 76801180 Nonpathogen - protein NP1057E 1 None None None 76802437 Nonpathogen - hypothetical protein NP3598A 2 None None None 76801943 Common - hypothetical protein NP2602A 17 COG1944 COG1944, Uncharacterized conserved protein Function unknown 76803016 Common gcvH glycin cleavage system H protein NP4772A 186 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 76802878 Common maa_1 galactoside O-acetyltransferase 1; maltose O-acetyltransferase 1 NP4490A 123 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 76802139 Nonpathogen - hypothetical protein NP2996A 4 None None None 76801387 Common abc07a1 ABC-type transport system ATP-binding protein I (probable substrates branched-chain/neutral amino acids) 3 NP1472A 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 76802502 Common csp1_2 probable cold shock protein NP3734A 156 COG1278 CspC, Cold shock proteins Transcription 76801572 Nonpathogen - hypothetical protein NP1848A 2 None None None 76802213 Nonpathogen - hypothetical protein NP3146A 3 None None None 76803220 Nonpathogen - hypothetical protein NP5184A 3 None None None 76801107 Common lon endopeptidase La NP0910A 205 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 76801647 Common abc10s ABC-type transport system periplasmic substrate-binding protein (probable substrates urea/short chain-amides) 1 NP2004A 116 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 76802680 Common apa probable bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) NP4092A 46 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 76802764 Nonpathogen - hypothetical protein NP4260A 4 None None None 76801137 Common guaD_1 probable nucleoside deaminase 1 (cytosine deaminase , guanine deaminase ) NP0972A 173 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 76803074 Nonpathogen rpl32R 50S ribosomal protein L32e NP4888A 34 COG1717 RPL32, Ribosomal protein L32E Translation, ribosomal structure and biogenesis 76802689 Nonpathogen - tRNA 2'-O-methylase NP4110A 31 COG1303 COG1303, Uncharacterized protein conserved in archaea Function unknown 76800924 Common tp53_1 predicted TRAP-type transport system periplasmic protein 1 NP0544A 87 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 76801461 Common - signal-transducing histidine kinase; probable GAF, PAS/PAC domain protein NP1622A 152 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76802249 Common - hexosyltransferase 2 NP3218A 209 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 76801579 Nonpathogen - hypothetical protein NP1862A 4 None None None 76801100 Nonpathogen - hypothetical protein NP0896A 1 None None None 76802046 Nonpathogen - hypothetical protein NP2808A 2 COG2259 COG2259, Predicted membrane protein Function unknown 76801488 Nonpathogen - probable transcription regulator NP1678A 3 COG1695 COG1695, Predicted transcriptional regulators Transcription 76802095 Common - response regulator NP2906A 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 76801094 Common agt_2 aminotransferase class V (Serine--pyruvate aminotransferase 2; Alanine--glyoxylate aminotransferase 2) NP0884A 168 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 76802173 Nonpathogen - hypothetical protein NP3066A 3 None None None 76803144 Nonpathogen - hypothetical protein NP5032A 2 COG3430 COG3430, Uncharacterized protein conserved in archaea Function unknown 76801440 Common mvaD diphosphomevalonate decarboxylase NP1580A 17 COG3407 MVD1, Mevalonate pyrophosphate decarboxylase Lipid metabolism 76802108 Common acd_7 acyl-CoA dehydrogenase 7 NP2934A 149 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 76802610 Nonpathogen - hypothetical protein NP3952A 12 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 76802997 Common abc20p ABC-type transport system permease protein (probable substrates zinc/manganese/metal ions) 2 NP4732A 185 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 76802979 Common - probable KaiC-like transcriptional regulator 1 NP4694A 71 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 76802540 Nonpathogen - H/ACA RNA-protein complex component Gar1 NP3810A 4 COG3277 GAR1, RNA-binding protein involved in rRNA processing Translation, ribosomal structure and biogenesis 76802366 Common phr_2 deoxyribodipyrimidine photolyase NP3456A 131 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 76800919 Nonpathogen - probable transcription regulator NP0534A 3 COG1309 AcrR, Transcriptional regulator Transcription 76801771 Common fadB_3 probable enoyl-CoA hydratase II 3 NP2256A 81 COG2030 MaoC, Acyl dehydratase Lipid metabolism 76801675 Common - hypothetical protein NP2060A 87 COG4907 COG4907, Predicted membrane protein Function unknown 76801398 Common - probable transcription regulator NP1496A 63 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 76800864 Nonpathogen - nonhistone chromosomal protein NP0424A 8 None None None 76803090 Nonpathogen - hypothetical protein NP4920A 1 None None None 76803178 Nonpathogen - hypothetical protein NP5100A 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 76803173 Common hit_2 probable histidine triad (HIT) hydrolase 2 (probable bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) ) NP5090A 235 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 76800710 Common rpoB2 DNA-directed RNA polymerase subunit beta'' NP0110A 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 76802507 Nonpathogen - hypothetical protein NP3744A 1 None None None 76801724 Nonpathogen flaJ flagellar assembly protein J NP2160A 21 COG1955 FlaJ, Archaeal flagella assembly protein J Cell motility and secretion / Intracellular trafficking and secretion 76801468 Common - hypothetical protein NP1636A 39 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 76800869 Nonpathogen - hypothetical protein NP0434A 4 None None None 76801835 Common glmS_2 glutamine--fructose-6-phosphate transaminase (isomerizing) 2 NP2384A 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 76800719 Nonpathogen - hypothetical protein NP0128A 4 None None None 76802857 Nonpathogen rpl12p 50S ribosomal protein L12P NP4448A 32 COG2058 RPP1A, Ribosomal protein L12E/L44/L45/RPP1/RPP2 Translation, ribosomal structure and biogenesis 76801950 Common tp16 major facilitator family transporter 6 (probable phosphoglycerate transporter) NP2616A 41 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 76802867 Nonpathogen - hypothetical protein NP4468A 1 None None None 76802206 Nonpathogen - hypothetical protein NP3132A 1 None None None 76800913 Common - probable dehydrogenase/ reductase 4 NP0522A 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 76801698 Nonpathogen - conserved flagella cluster protein NP2108A 2 COG1300 SpoIIM, Uncharacterized membrane protein Function unknown 76800862 Nonpathogen rpl10e 50S ribosomal protein L10e NP0416A 34 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 76801958 Common fadA_1 enoyl-CoA hydratase I 1 NP2632A 188 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 76802606 Nonpathogen - hypothetical protein NP3942A 1 None None None 76803193 Common - probable GAF, PAS/PAC domain protein; probable predicted DNA binding protein NP5130A 57 COG3413 COG3413, Predicted DNA binding protein General function prediction only 76802531 Common ferA_5 probable ferredoxin I 5 NP3792A 7 COG2871 NqrF, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF Energy production and conversion 76801713 Common mobA molybdopterin-guanine dinucleotide biosynthesis protein A NP2138A 77 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 76802539 Nonpathogen - hypothetical protein NP3808A 14 COG3389 COG3389, Uncharacterized protein conserved in archaea Function unknown 76802635 Common lhr Lhr-like helicase NP4002A 238 COG1201 Lhr, Lhr-like helicases General function prediction only 76801969 Common - subtilisin-like serine protease NP2654A 86 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 76802446 Nonpathogen - hypothetical protein NP3616A 3 None None None 76802497 Common - homolog to GlpG-like protein NP3724A 63 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 76803012 Common crtI_1 phytoene dehydrogenase 1 (phytoene desaturase) NP4764A 82 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 76803055 Nonpathogen - hypothetical protein NP4850A 1 None None None 76802970 Common pmm_2 phosphohexomutase 2 (phosphoglucomutase , phosphomannomutase ) NP4676A 239 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 76800794 Nonpathogen - hypothetical protein NP0278A 1 None None None 76801848 Common thrS threonine--tRNA ligase NP2410A 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 76802784 Common tpa05 transport ATPase 5 (probable substrates copper/metal cation) NP4300A 229 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 76802754 Common acs_1 acyl-CoA synthetase I 1 NP4240A 214 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 76803107 Common - anaerobic dehydrogenase cluster protein NP4954A 15 None None None 76803292 Nonpathogen - hypothetical protein NP5330A 1 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 76800849 Common - homolog 2 to thiosulfate sulfurtransferase NP0390A 63 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 76802523 Nonpathogen - probable transcription regulator NP3776A 3 None None None 76801509 Common htr29 transducer protein htr29 NP1720A 155 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 76801726 Nonpathogen - flagella cluster protein NP2164A 1 None None None 76800984 Common - hypothetical protein NP0664A 23 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 76802512 Common - DNA N-glycosylase / DNA lyase NP3754A 24 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 76802066 Common rps2P 30S ribosomal protein S2 NP2848A 123 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 76803114 Common - iron-sulfur binding protein, ferredoxin-like NP4970A 53 COG1148 HdrA, Heterodisulfide reductase, subunit A and related polyferredoxins Energy production and conversion 76800850 Common nudF_1 probable ADP-ribose pyrophosphatase NP0392A 40 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 76800742 Common abc09s ABC-type transport system periplasmic substrate-binding protein (probable substrates branched-chain/neutral amino acids amide) 5 NP0174A 39 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 76800908 Common - predicted electron-transferring-flavoprotein dehydrogenase 3 NP0512A 103 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 76801792 Common nuoH NADH dehydrogenase-like complex, subunit H NP2298A 187 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 76802751 Common - biotin operon protein NP4234A 9 None None None 76801303 Nonpathogen - hypothetical protein NP1304A 4 None None None 76802253 Common - homolog to phospholipase NP3226A 9 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 76803165 Nonpathogen rps24e 30S ribosomal protein S24e NP5074A 28 COG2004 RPS24A, Ribosomal protein S24E Translation, ribosomal structure and biogenesis 76801051 Common ilvE_2 branched-chain amino acid aminotransferase 2 NP0798A 199 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 76800890 Nonpathogen polA2 DNA polymerase II large subunit NP0476A 25 COG1933 COG1933, Archaeal DNA polymerase II, large subunit DNA replication, recombination, and repair 76801920 Nonpathogen - hypothetical protein NP2556A 2 None None None 76802551 Nonpathogen - hypothetical protein NP3832A 3 None None None 76802742 Nonpathogen - hypothetical protein NP4216A 1 None None None 76803024 Common guaD_3 probable nucleoside deaminase 3 (cytosine deaminase , guanine deaminase ) NP4788A 75 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 76802625 Nonpathogen aroK shikimate kinase NP3982A 27 COG1685 COG1685, Archaeal shikimate kinase Amino acid transport and metabolism / Coenzyme metabolism 76801046 Nonpathogen - hypothetical protein NP0788A 2 None None None 76801299 Nonpathogen - hypothetical protein NP1296A 18 COG1356 COG1356, Uncharacterized protein conserved in archaea Function unknown 76802804 Nonpathogen - hypothetical protein NP4340A 1 None None None 76801038 Nonpathogen - hypothetical protein NP0772A 12 COG1255 COG1255, Uncharacterized protein conserved in archaea Function unknown 76800947 Nonpathogen - hypothetical protein NP0590A 9 COG3364 COG3364, Zn-ribbon containing protein General function prediction only 76802335 Common cbs_4 CBS domain protein 4 NP3394A 146 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 76801663 Nonpathogen abc29p1 ABC-type transport system permease protein 1 (heme exporter protein B) NP2036A 13 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 76800807 Common rps10p 30S ribosomal protein S10P NP0306A 235 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 76802226 Nonpathogen - hypothetical protein NP3172A 4 None None None 76802506 Common hflX GTP-binding protein NP3742A 210 COG2262 HflX, GTPases General function prediction only 76802399 Nonpathogen - hypothetical protein NP3522A 4 None None None 76802157 Nonpathogen - probable cell surface glycoprotein NP3032A 1 COG2706 COG2706, 3-carboxymuconate cyclase Carbohydrate transport and metabolism 76800822 Common - probable nuclease domain protein/ probable ATP-dependent helicase NP0336A 217 COG1111 MPH1, ERCC4-like helicases DNA replication, recombination, and repair 76802372 Nonpathogen - hypothetical protein NP3468A 18 COG1885 COG1885, Uncharacterized protein conserved in archaea Function unknown 76800774 Common - hypothetical protein NP0238A 37 COG1637 COG1637, Predicted nuclease of the RecB family DNA replication, recombination, and repair 76801895 Nonpathogen - hypothetical protein NP2504A 1 None None None 76802214 Nonpathogen - hypothetical protein NP3148A 4 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 76802379 Common top6B DNA topoisomerase VI subunit B NP3482A 37 COG1389 COG1389, DNA topoisomerase VI, subunit B DNA replication, recombination, and repair 76802877 Common - predicted oxidoreductase 2 NP4488A 198 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 76803300 Nonpathogen - hypothetical protein NP5346A 1 None None None 76801552 Nonpathogen - hypothetical protein NP1808A 3 COG3011 COG3011, Uncharacterized protein conserved in bacteria Function unknown 76802443 Common tp22 major facilitator family transporter 12 NP3610A 54 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 76801073 Common tp49_1 putative monovalent cation/H+ antiporter subunit E NP0842A 30 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 76801542 Nonpathogen - hypothetical protein NP1786A 6 None None None 76801451 Nonpathogen - hypothetical protein NP1602A 1 None None None 76802191 Nonpathogen - hypothetical protein NP3102A 5 None None None 76800859 Nonpathogen - hypothetical protein NP0410A 5 None None None 76800857 Nonpathogen - translation initiation factor IF-2 subunit beta NP0406A 33 COG1601 GCD7, Translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain Translation, ribosomal structure and biogenesis 76801804 Common ugd_2 UDP-glucose 6-dehydrogenase 2 NP2322A 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 76803214 Nonpathogen - hypothetical protein NP5172A 3 None None None 76803187 Common - endonuclease IV NP5118A 97 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 76800660 Common hsp20_1 hsp20-type chaperone NP0010A 37 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 76802125 Nonpathogen cbaE cytochrome-ba3 oxidase subunit NP2968A 1 None None None 76801084 Common - hypothetical protein NP0864A 141 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 76801747 Common - isoleucine cluster protein NP2208A 200 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 76800988 Common - homolog 7 to S-adenosylmethionine-dependent methyltransferase 3 NP0672A 73 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 76802608 Nonpathogen moaD_3 homolog to molybdopterin converting factor, small subunit NP3946A 1 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 76802440 Common tp41_2 Kef-type transport system 2 (probable substrate potassium), subunit 2 NP3604A 136 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 76801981 Nonpathogen - hypothetical protein NP2678A 4 None None None 76802587 Nonpathogen - hypothetical protein NP3904A 2 COG4711 COG4711, Predicted membrane protein Function unknown 76801147 Nonpathogen - hypothetical protein NP0992A 1 COG4872 COG4872, Predicted membrane protein Function unknown 76802132 Common purL phosphoribosylformylglycinamidine synthase , component II NP2982A 233 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 76801382 Common fadA_5 probable enoyl-CoA hydratase I 5 NP1462A 179 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 76801363 Nonpathogen - hypothetical protein NP1424A 6 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 76801279 Common apt_2 adenine phosphoribosyltransferase NP1254A 18 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 76803208 Nonpathogen - hypothetical protein NP5160A 4 None None None 76802934 Nonpathogen - hypothetical protein NP4602A 1 None None None 76802904 Nonpathogen - hypothetical protein NP4542A 25 COG1836 COG1836, Predicted membrane protein Function unknown 76801354 Nonpathogen - hypothetical protein NP1406A 4 None None None 76803133 Common purQ phosphoribosylformylglycinamidine synthase , component I NP5010A 232 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 76802237 Common hit_1 probable histidine triad (HIT) hydrolase 1 (probable bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) ) NP3194A 122 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 76802072 Nonpathogen - aspartic acid-rich protein NP2860A 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 76800786 Nonpathogen ubiA prenyltransferase NP0262A 19 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 76802636 Common nirA_3 probable ferredoxin--nitrite reductase 3 NP4004A 187 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 76801719 Nonpathogen - flagella cluster protein NP2150A 1 None None None 76801096 Nonpathogen tp20 major facilitator family transporter 10 (probable multidrug efflux transporter, probable tetracyclin resistance protein) NP0888A 4 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 76801710 Common - hypothetical protein NP2132A 91 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 76801243 Common ths_3 thermosome subunit 3 NP1182A 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 76801392 Nonpathogen - hypothetical protein NP1482A 1 None None None 76801864 Common abc28a ABC-type transport system ATP-binding protein NP2442A 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 76803290 Nonpathogen - probable transcription regulator NP5326A 10 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 76802174 Nonpathogen - hypothetical protein NP3068A 16 COG3388 COG3388, Uncharacterized protein conserved in archaea Function unknown 76803052 Nonpathogen - hypothetical protein NP4844A 7 COG4749 COG4749, Uncharacterized protein conserved in archaea Function unknown 76801069 Common tp49_5 pH adaptation potassium efflux system protein B 2; sodium/hydrogen antiporter subunit NP0834A 23 COG2111 MnhB, Multisubunit Na+/H+ antiporter, MnhB subunit Inorganic ion transport and metabolism 76801028 Nonpathogen - hypothetical protein NP0752A 2 None None None 76802948 Nonpathogen - hypothetical protein NP4632A 2 None None None 76802929 Common - probable stress response protein NP4592A 28 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 76803152 Common - hypothetical protein NP5048A 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 76800691 Nonpathogen - rib operon protein NP0072A 33 COG1339 COG1339, Transcriptional regulator of a riboflavin/FAD biosynthetic operon Transcription / Coenzyme metabolism 76801813 Nonpathogen - hypothetical protein NP2340A 1 None None None 76803088 Common truB H/ACA RNA-protein complex component Cbf5p NP4916A 239 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 76800990 Nonpathogen - hypothetical protein NP0676A 7 None None None 76803008 Common - hypothetical protein NP4756A 89 COG0327 COG0327, Uncharacterized conserved protein Function unknown 76802772 Common graD_6 sugar nucleotidyltransferase (probable glucose-1-phosphate thymidylyltransferase ) 6 NP4276A 241 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 76801222 Common pepB_3 aminopeptidase (similar to leucyl aminopeptidase, aminopeptidase T) 3 NP1140A 64 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 76800665 Common pimT_2 protein-L-isoaspartate O-methyltransferase NP0020A 141 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 76801977 Common - homolog 4 to thiosulfate sulfurtransferase / hydrolase (probable hydroxyacylglutathione hydrolase ) 2 NP2670A 203 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 76802345 Common ubiD_1 prenyl carboxy-lyase 1 (probable 3-octaprenyl-4-hydroxybenzoate carboxy-lyase ) NP3414A 144 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 76803004 Common metB cystathionine synthase/lyase (cystathionine gamma-synthase , cystathionine gamma-lyase , cystathionine beta-lyase ) NP4746A 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 76801342 Common tpa06 transport ATPase 6 (probable substrate arsenite) NP1382A 87 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 76801135 Common - S-adenosyl-L-homocysteine hydrolase NP0968A 178 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 76801207 Nonpathogen - conserved cobalamin operon protein NP1110A 4 None None None 76802434 Common - hypothetical protein NP3592A 8 COG3350 COG3350, Uncharacterized conserved protein Function unknown 76802284 Nonpathogen - hypothetical protein NP3290A 1 None None None 76800658 Common - ABC-type transport system ATP-binding protein NP0006A 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 76802259 Common - probable integrase NP3238A 15 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 76800931 Common oxdhB 2-oxoacid dehydrogenase E1 component, beta subunit NP0558A 215 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 76803310 Nonpathogen - hypothetical protein NP5366A 2 None None None 76803138 Nonpathogen moaD_1 probable molybdopterin converting factor, small subunit 1 NP5020A 25 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 76802142 Nonpathogen - probable transcription regulator NP3002A 4 COG1695 COG1695, Predicted transcriptional regulators Transcription 76801658 Nonpathogen - hypothetical protein NP2026A 19 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 76801004 Common nolA_2 NADH dehydrogenase 32K chain homolog NP0704A 87 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 76801873 Nonpathogen - conserved cox cluster protein NP2460A 1 None None None 76801829 Nonpathogen - hypothetical protein NP2372A 1 None None None 76801275 Common hemL glutamate-1-semialdehyde 2,1-aminomutase NP1246A 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 76801427 Nonpathogen - hypothetical protein NP1554A 3 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 76800962 Common guaAa_1 GMP synthase subunit A NP0620A 238 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 76802517 Common dld_1 probable D-lactate dehydrogenase 1 NP3764A 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 76803059 Nonpathogen rplW 50S ribosomal protein L23 NP4858A 35 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 76800903 Common - probable dehydrogenase/ reductase 12 NP0502A 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 76802149 Common sufB_3 ABC-type transport system permease protein (probable Fe-S cluster assembly protein) 3 NP3016A 186 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 76801651 Common ureA urease subunit gamma NP2012A 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 76801013 Common - hypothetical protein NP0722A 116 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 76802205 Common - hypothetical protein NP3130A 71 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 76801254 Common - predicted phosphoribosyltransferase NP1204A 45 COG2236 COG2236, Predicted phosphoribosyltransferases General function prediction only 76801111 Common ogt probable methylated-DNA--protein-cysteine methyltransferase NP0918A 12 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 76801172 Nonpathogen - hypothetical protein NP1042A 1 None None None 76802548 Nonpathogen - hypothetical protein NP3826A 1 None None None 76802660 Common thiM hydroxyethylthiazole kinase NP4052A 76 COG2145 ThiM, Hydroxyethylthiazole kinase, sugar kinase family Coenzyme metabolism 76801114 Nonpathogen - transcription regulator NP0924A 4 COG1522 Lrp, Transcriptional regulators Transcription 76801682 Nonpathogen - hypothetical protein NP2076A 2 None None None 76800966 Nonpathogen - hypothetical protein NP0628A 9 COG1430 COG1430, Uncharacterized conserved protein Function unknown 76802457 Common - probable tyrosine recombinase NP3640A 136 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 76801056 Common - hypothetical protein NP0808A 30 COG1650 COG1650, Uncharacterized protein conserved in archaea Function unknown 76801980 Common tp06 transporter 6 (probable substrates cationic amino acids) NP2676A 75 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 76802004 Common menF isochorismate synthase NP2724A 223 COG1169 MenF, Isochorismate synthase Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism 76802841 Nonpathogen - hypothetical protein NP4416A 22 COG2118 COG2118, DNA-binding protein General function prediction only 76800793 Nonpathogen - hypothetical protein NP0276A 1 None None None 76803283 Nonpathogen - predicted Fe-S oxidoreductase NP5312A 28 COG1031 COG1031, Uncharacterized Fe-S oxidoreductase Energy production and conversion 76801609 Common - hexosyltransferase 3 NP1922A 194 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 76802953 Common - hypothetical protein NP4642A 4 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 76802267 Common - probable HNH-type endonuclease NP3256A 6 COG3183 COG3183, Predicted restriction endonuclease Defense mechanisms 162329650 Common secF preprotein translocase subunit SecF NP2524A 69 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 76803248 Nonpathogen - parA domain ATP-binding protein NP5240A 14 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 76802392 Common ndh probable NADH dehydrogenase NP3508A 185 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 76800740 Common abc09p2 ABC-type transport system permease protein II (probable substrates branched-chain/neutral amino acids) 5 NP0170A 105 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 76801245 Common - predicted dehydrogenase NP1186A 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 76801154 Nonpathogen - probable ribosomal RNA assembly protein NP1006A 34 COG1094 COG1094, Predicted RNA-binding protein (contains KH domains) General function prediction only 76803084 Nonpathogen - hypothetical protein NP4908A 1 None None None 76802296 Nonpathogen - hypothetical protein NP3314A 1 None None None 76802989 Common - hypothetical protein NP4714A 87 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 76801515 Common - hypothetical protein NP1732A 15 COG3422 COG3422, Uncharacterized conserved protein Function unknown 76801827 Nonpathogen - hypothetical protein NP2368A 1 None None None 76801632 Nonpathogen - conserved CTP/GMP synthase operon protein NP1972A 4 None None None 76802416 Common menA_2 homolog to 1,4-dihydroxy-2-naphthoate octaprenyltransferase NP3556A 25 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 76801646 Common abc10p1 ABC-type transport system permease protein I (probable substrates branched-chain/neutral amino acids) NP2002A 133 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 76803047 Common sopII sensory rhodopsin II NP4834A 12 COG5524 COG5524, Bacteriorhodopsin General function prediction only 76803275 Nonpathogen - hypothetical protein NP5296A 1 COG5524 COG5524, Bacteriorhodopsin General function prediction only 76802595 Nonpathogen abc11p ABC-type transport system permease protein (probable substrate copper) 1 NP3920A 2 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 76801944 Nonpathogen - hypothetical protein NP2604A 5 None None None 76801122 Common - homolog to nitrogen fixation protein NifU NP0940A 168 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 76801179 Common - methylenetetrahydromethanopterin reductase NP1056A 58 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 76802162 Common abc22a ABC-type transport system ATP-binding protein NP3044A 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 76803305 Nonpathogen - hypothetical protein NP5356A 1 None None None 76803038 Common qor_1 NADPH:quinone reductase 1 NP4816A 214 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 76800860 Nonpathogen - hypothetical protein NP0412A 4 None None None 76801679 Nonpathogen - hypothetical protein NP2068A 1 None None None 76801677 Nonpathogen nop56 probable pre-rRNA-processing protein nop56 NP2064A 34 COG1498 SIK1, Protein implicated in ribosomal biogenesis, Nop56p homolog Translation, ribosomal structure and biogenesis 76800713 Common rpoA2 DNA-directed RNA polymerase subunit A NP0116A 45 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 76803104 Nonpathogen - hypothetical protein NP4948A 1 None None None 76802093 Nonpathogen - hypothetical protein NP2902A 20 COG3294 COG3294, Uncharacterized conserved protein Function unknown 76802533 Nonpathogen - hypothetical protein NP3796A 3 None None None 76802560 Nonpathogen - hypothetical protein NP3850A 1 None None None 76801885 Nonpathogen - hypothetical protein NP2484A 7 COG1503 eRF1, Peptide chain release factor 1 (eRF1) Translation, ribosomal structure and biogenesis 76803057 Common rpl3p 50S ribosomal protein L3P NP4854A 137 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 76800936 Nonpathogen - conserved psp operon protein NP0568A 1 None None None 76800840 Nonpathogen - hypothetical protein NP0372A 4 None None None 76803075 Nonpathogen rpl19e 50S ribosomal protein L19e NP4890A 34 COG2147 RPL19A, Ribosomal protein L19E Translation, ribosomal structure and biogenesis 76801485 Nonpathogen - hypothetical protein NP1672A 4 None None None 76802554 Nonpathogen - hypothetical protein NP3838A 4 None None None 76801152 Common - hypothetical protein NP1002A 37 COG0622 COG0622, Predicted phosphoesterase General function prediction only 76802789 Nonpathogen rpl37e 50S ribosomal protein L37e NP4310A 29 COG2126 RPL37A, Ribosomal protein L37E Translation, ribosomal structure and biogenesis 76801888 Nonpathogen - hypothetical protein NP2490A 15 COG1777 COG1777, Predicted transcriptional regulators Transcription 76800867 Nonpathogen - hypothetical protein NP0430A 4 None None None 76802491 Common fdhA_2a formate dehydrogenase 2, alpha subunit (nonfunctional, N-terminal part, interrupted by ISH) NP3710A 192 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 76801347 Nonpathogen - hypothetical protein NP1392A 9 None None None 76800950 Nonpathogen cdc6_1 cell division control protein cdc6 homolog NP0596A 31 COG1474 CDC6, Cdc6-related protein, AAA superfamily ATPase DNA replication, recombination, and repair / Posttranslational modification, protein turnover, chaperones 76801041 Nonpathogen - hypothetical protein NP0778A 2 None None None 76801337 Nonpathogen - hypothetical protein NP1372A 1 None None None 76801781 Nonpathogen - hypothetical protein NP2276A 9 None None None 76801707 Nonpathogen - hypothetical protein NP2126A 4 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 76800766 Nonpathogen tp48_2 transport system 48 (probable substrate zinc), subunit 2 NP0222A 18 COG1824 COG1824, Permease, similar to cation transporters Inorganic ion transport and metabolism 76803159 Common - predicted cell surface protein/ lipoprotein NP5062A 136 COG1520 COG1520, FOG: WD40-like repeat Function unknown 76801621 Common - sugar metabolism cluster protein (predicted glutamine amidotransferase) NP1950A 136 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 76800957 Common ileS isoleucyl-tRNA synthetase NP0610A 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 76802647 Common - transcription regulator NP4026A 92 COG1522 Lrp, Transcriptional regulators Transcription 76800718 Common - probable glucose dehydrogenase 2, type B; probable L-sorbosone dehydrogenase 2 NP0126A 111 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 76802134 Common - homolog to ABC-type transport system periplasmic substrate-binding protein (probable substrates dipeptide/oligopeptide/nickel) NP2986A 78 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 76802053 Common moaA molybdenum cofactor biosynthesis protein A NP2822A 195 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 76802861 Common - GTP-binding protein NP4456A 184 COG1163 DRG, Predicted GTPase General function prediction only 76802083 Nonpathogen - hypothetical protein NP2882A 9 COG4746 COG4746, Uncharacterized protein conserved in archaea Function unknown 76802630 Nonpathogen - conserved primase operon protein NP3992A 7 COG1711 COG1711, Uncharacterized protein conserved in archaea Function unknown 76802949 Common - IS1341-type transposase NP4634A 47 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 76803123 Nonpathogen - hypothetical protein NP4988A 1 None None None 76803128 Nonpathogen - hypothetical protein NP4998A 1 None None None 76803141 Common - predicted ATPase NP5026A 32 COG0433 COG0433, Predicted ATPase General function prediction only 76803267 Common thrC_1 threonine synthase 1 NP5280A 199 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 76802681 Nonpathogen - hypothetical protein NP4094A 5 COG1718 RIO1, Serine/threonine protein kinase involved in cell cycle control Signal transduction mechanisms / Cell division and chromosome partitioning 76802035 Common - hypothetical protein NP2786A 5 COG2402 COG2402, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 76801628 Common gpmA phosphoglyceromutase NP1964A 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 76802779 Nonpathogen - hypothetical protein NP4290A 6 None None None 76801184 Nonpathogen tbpE transcription factor NP1064A 34 COG2101 SPT15, TATA-box binding protein (TBP), component of TFIID and TFIIIB Transcription 76802567 Common - probable helicase NP3864A 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 76801165 Nonpathogen atpF V-type ATP synthase subunit F NP1028A 13 COG1436 NtpG, Archaeal/vacuolar-type H+-ATPase subunit F Energy production and conversion 76802179 Common aroA 3-phosphoshikimate 1-carboxyvinyltransferase NP3078A 229 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 76803143 Nonpathogen - hypothetical protein NP5030A 4 None None None 76801102 Common rfc replication factor C small subunit NP0900A 249 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 76801219 Nonpathogen - hypothetical protein NP1134A 11 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 76801384 Common abc07p1 ABC-type transport system permease protein I (probable substrates branched-chain/neutral amino acids) 3 NP1466A 120 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 76802172 Common - nirG protein homolog / nirH protein homolog NP3064A 52 COG1522 Lrp, Transcriptional regulators Transcription 76801945 Common acaB_1 acetyl-CoA C-acyltransferase 1 NP2606A 164 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 76802794 Nonpathogen - hypothetical protein NP4320A 16 COG3174 COG3174, Predicted membrane protein Function unknown 76802483 Common gltX glutamyl-tRNA synthetase NP3694A 248 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 76801670 Common glyA glycine hydroxymethyltransferase NP2050A 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 76802303 Nonpathogen - hypothetical protein NP3328A 1 None None None 76802890 Nonpathogen - hypothetical protein NP4514A 4 None None None 76802686 Nonpathogen - hypothetical protein NP4104A 9 COG4044 COG4044, Uncharacterized protein conserved in archaea Function unknown 76801754 Common - probable dehydrogenase/ reductase 11 NP2222A 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 76802557 Common - homolog 1 to PPE-repeat proteins NP3844A 4 None None None 76802014 Nonpathogen - hypothetical protein NP2744A 11 COG2835 COG2835, Uncharacterized conserved protein Function unknown 76802202 Nonpathogen - hypothetical protein NP3124A 1 None None None 76800696 Common hisH imidazole glycerol phosphate synthase subunit HisH NP0082A 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 76801656 Nonpathogen - hypothetical protein NP2022A 6 COG2457 COG2457, Uncharacterized conserved protein Function unknown 76801313 Common - hemAT domain protein NP1324A 24 None None None 76802217 Nonpathogen - hypothetical protein NP3154A 34 COG1736 DPH2, Diphthamide synthase subunit DPH2 Translation, ribosomal structure and biogenesis 76802639 Nonpathogen - hypothetical protein NP4010A 4 None None None 76801109 Nonpathogen - hypothetical protein NP0914A 1 None None None 76801260 Common smc chromosome partition protein NP1216A 181 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 76802044 Common - monooxygenase (homolog to alkanesulfonate monooxygenase) 2 NP2804A 114 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 76803050 Nonpathogen - hypothetical protein NP4840A 11 COG2405 COG2405, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 76802079 Nonpathogen - hypothetical protein NP2874A 22 COG1107 COG1107, Archaea-specific RecJ-like exonuclease, contains DnaJ-type Zn finger domain DNA replication, recombination, and repair 76801087 Nonpathogen coaE dephospho-CoA kinase NP0870A 34 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 76801463 Nonpathogen - hypothetical protein NP1626A 1 None None None 76800752 Nonpathogen trm1 N(2),N(2)-dimethylguanosine tRNA methyltransferase NP0194A 38 COG1867 TRM1, N2,N2-dimethylguanosine tRNA methyltransferase Translation, ribosomal structure and biogenesis 76802718 Nonpathogen - predicted electron-transferring-flavoprotein dehydrogenase 1 NP4168A 19 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 76802766 Common sdhA succinate dehydrogenase , subunit A (flavoprotein) NP4264A 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 76801319 Nonpathogen - hypothetical protein NP1336A 2 None None None 76802816 Common accB_2 acyl-CoA carboxylase 2, carboxyltransferase component (beta subunit) NP4364A 215 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 76802463 Nonpathogen - hypothetical protein NP3654A 3 None None None 76801745 Common ilvB acetolactate synthase , large subunit NP2202A 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 76802181 Common aroC chorismate synthase NP3082A 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 76802725 Nonpathogen - hypothetical protein NP4182A 2 None None None 76802897 Common pyroA pyridoxine biosynthesis protein NP4528A 87 COG0214 SNZ1, Pyridoxine biosynthesis enzyme Coenzyme metabolism 76802025 Nonpathogen - hypothetical protein NP2766A 2 None None None 76802361 Common prkA_2 predicted serine protein kinase 2 NP3446A 22 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 76802018 Common - transcription regulator NP2752A 141 COG1522 Lrp, Transcriptional regulators Transcription 76801597 Common - hydrolase (probable hydroxyacylglutathione hydrolase ) 11 NP1898A 59 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 76802542 Common btuF corrinoid ABC transporter substrate-binding protein NP3814A 103 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 76803241 Common - NADPH dehydrogenase (old yellow enzyme); 2,4-dienoyl-CoA reductase (NADPH) NP5226A 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 76801288 Common entB_1 probable isochorismatase 1; probable nicotinamidase 1; probable N-carbamoylsarcosine amidase 1 NP1274A 92 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 76802696 Nonpathogen - transcription regulator NP4124A 11 COG3355 COG3355, Predicted transcriptional regulator Transcription 76802893 Common hemY hypothetical protein NP4520A 31 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 76802112 Common - IS1341-type transposase NP2942A 24 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 76801764 Nonpathogen - hypothetical protein NP2242A 1 None None None 76802410 Common - thioredoxin reductase homolog NP3544A 10 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 76800911 Common - hypothetical protein NP0518A 84 COG0824 FcbC, Predicted thioesterase General function prediction only 76802322 Nonpathogen - phosphopantetheine adenylyltransferase NP3368A 27 COG1019 COG1019, Predicted nucleotidyltransferase General function prediction only 76802936 Common - signal-transducing histidine kinase; PAS/PAC domain protein NP4606A 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76801376 Nonpathogen - hypothetical protein NP1450A 9 COG2512 COG2512, Uncharacterized membrane-associated protein/domain Function unknown 76800724 Common - signal-transducing histidine kinase; response regulator NP0138A 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76801544 Nonpathogen - hypothetical protein NP1792A 4 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 76802356 Common - homolog to stress response protein NP3436A 12 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 76802318 Nonpathogen - conserved tyrA operon protein NP3360A 10 COG5459 COG5459, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 76801837 Nonpathogen - hypothetical protein NP2388A 1 None None None 76801537 Common abc04p2_1 ABC-type transport system permease protein II 1 (probable substrates glutamine/glutamate/polar amino acids) NP1776A 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 76802394 Common cdd cytidine deaminase NP3512A 123 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 76801415 Common purA adenylosuccinate synthase NP1530A 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 76802832 Nonpathogen - hypothetical protein NP4396A 2 None None None 76800706 Common abc30p ABC-type transport system permease protein (probable substrates macrolides) NP0102A 156 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 76800810 Nonpathogen - hypothetical protein NP0312A 6 COG1547 COG1547, Uncharacterized conserved protein Function unknown 76800728 Nonpathogen - homolog 5 to transducer protein NP0146A 1 None None None 76802224 Common etfA electron transfer flavoprotein, alpha subunit NP3168A 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 76801235 Common - hypothetical protein NP1166A 4 COG1269 NtpI, Archaeal/vacuolar-type H+-ATPase subunit I Energy production and conversion 76802274 Common - hypothetical protein NP3270A 12 COG1203 COG1203, Predicted helicases General function prediction only 76802968 Nonpathogen - sugar metabolism cluster protein NP4672A 1 None None None 76802381 Nonpathogen - hypothetical protein NP3486A 4 None None None 76802977 Nonpathogen - hypothetical protein NP4690A 1 None None None 76803264 Common - signal-transducing histidine kinase; probable GAF, PAS/PAC domain protein NP5274A 214 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76801776 Nonpathogen - hypothetical protein NP2266A 1 None None None 76802312 Nonpathogen - hypothetical protein NP3348A 2 None None None 76802255 Nonpathogen pssA probable CDP-diacylglycerol--serine O-phosphatidyltransferase NP3230A 4 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 76803028 Nonpathogen - hypothetical protein NP4796A 29 COG1709 COG1709, Predicted transcriptional regulator Transcription 76801933 Nonpathogen - hypothetical protein NP2582A 1 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 76803223 Nonpathogen - conserved rnhA operon protein NP5190A 3 None None None 76800893 Nonpathogen polA1 DNA polymerase II small subunit NP0482A 24 COG1311 HYS2, Archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B DNA replication, recombination, and repair 76802927 Nonpathogen - hypothetical protein NP4588A 2 None None None 76802445 Nonpathogen - hypothetical protein NP3614A 1 COG3462 COG3462, Predicted membrane protein Function unknown 76802052 Common - hypothetical protein NP2820A 27 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 76802679 Nonpathogen - ribosomal protein S10 homolog NP4090A 7 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 76801580 Nonpathogen - hypothetical protein NP1864A 3 None None None 76800852 Nonpathogen - hypothetical protein NP0396A 4 COG4531 ZnuA, ABC-type Zn2+ transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 76802952 Nonpathogen - hypothetical protein (nonfunctional, C-terminal part, interrupted by ISH) NP4640A 2 None None None 76802571 Common - ATP-dependent helicase NP3872A 176 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 76801993 Common - hypothetical protein NP2702A 38 COG1916 COG1916, Uncharacterized homolog of PrgY (pheromone shutdown protein) Function unknown 76801402 Common abc31a ABC-type transport system ATP-binding protein NP1504A 226 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 76802048 Common - hypothetical protein NP2812A 144 COG1733 COG1733, Predicted transcriptional regulators Transcription 76802007 Common menB naphthoate synthase NP2730A 176 COG0447 MenB, Dihydroxynaphthoic acid synthase Coenzyme metabolism 76800839 Nonpathogen - hypothetical protein NP0370A 4 None None None 76802889 Nonpathogen - hypothetical protein NP4512A 1 None None None 76800834 Common idiB_1 isopentenyl pyrophosphate isomerase NP0360A 81 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 76800802 Common - IS1341-type transposase NP0294A 52 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 76802675 Common - transcription regulator NP4082A 75 COG0819 TenA, Putative transcription activator Transcription 76801412 Common pan_2 proteasome-activating nucleotidase NP1524A 249 COG1222 RPT1, ATP-dependent 26S proteasome regulatory subunit Posttranslational modification, protein turnover, chaperones 76801447 Common fba_1 fructose-bisphosphate aldolase 1 NP1594A 97 COG1830 FbaB, DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes Carbohydrate transport and metabolism 76802473 Common hemK protein methyltransferase NP3674A 90 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 76801490 Common - subtilisin-like serine protease NP1682A 89 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 76802059 Nonpathogen rpoD DNA-directed RNA polymerase subunit D NP2834A 36 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 76802749 Common bioD dethiobiotin synthase NP4230A 95 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 76802333 Nonpathogen - probable cell surface glycoprotein NP3390A 4 COG3889 COG3889, Predicted solute binding protein General function prediction only 76802602 Common nosL predicted lipoprotein NosL NP3934A 14 COG4314 NosL, Predicted lipoprotein involved in nitrous oxide reduction Energy production and conversion 76803212 Nonpathogen - hypothetical protein NP5168A 27 COG1992 COG1992, Uncharacterized conserved protein Function unknown 76801292 Nonpathogen - replication factor A NP1282A 17 COG1599 RFA1, Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins DNA replication, recombination, and repair 76801563 Nonpathogen - hypothetical protein NP1830A 4 None None None 76801132 Common rad3a probable DNA repair helicase NP0960A 63 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 76802197 Nonpathogen trxA_5 thioredoxin NP3114A 4 None None None 76803098 Nonpathogen - hypothetical protein NP4936A 2 None None None 76803303 Nonpathogen - hypothetical protein NP5352A 1 None None None 76802370 Common accB_3 acyl-CoA carboxylase 3, carboxyltransferase component (beta subunit) NP3464A 154 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 76802262 Nonpathogen - hypothetical protein NP3244A 2 None None None 76801229 Common - signal-transducing histidine kinase; PAS/PAC domain protein NP1154A 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76801806 Nonpathogen - hypothetical protein NP2326A 1 None None None 76802140 Nonpathogen - hypothetical protein NP2998A 2 None None None 76803219 Nonpathogen - hypothetical protein NP5182A 32 COG1602 COG1602, Uncharacterized conserved protein Function unknown 76801352 Common - hypothetical protein NP1402A 82 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 76803191 Common cbiP cobyric acid synthase NP5126A 150 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 76802623 Common proA gamma-glutamyl phosphate reductase NP3978A 194 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 76800814 Nonpathogen cca tRNA CCA-pyrophosphorylase NP0320A 34 COG1746 CCA1, tRNA nucleotidyltransferase (CCA-adding enzyme) Translation, ribosomal structure and biogenesis 76801768 Common phnP PhnP-like protein NP2250A 42 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 76802581 Nonpathogen - hypothetical protein NP3892A 2 None None None 76800788 Common - hypothetical protein NP0266A 26 COG4908 COG4908, Uncharacterized protein containing a NRPS condensation (elongation) domain General function prediction only 76800800 Nonpathogen - hypothetical protein NP0290A 3 None None None 76802239 Common - hypothetical protein NP3198A 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 76802130 Common asn asparagine synthase (glutamine-hydrolyzing) NP2978A 35 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 76802377 Nonpathogen - topoisomerase cluster protein NP3478A 1 None None None 76801810 Nonpathogen - hypothetical protein NP2334A 1 None None None 76801757 Common mtfK_1 FKBP-type peptidylprolyl isomerase 1 NP2228A 39 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 76801458 Nonpathogen rps27e 30S ribosomal protein S27e NP1616A 30 COG2051 RPS27A, Ribosomal protein S27E Translation, ribosomal structure and biogenesis 76801368 Nonpathogen - hypothetical protein NP1434A 6 COG2246 COG2246, Predicted membrane protein Function unknown 76801893 Nonpathogen moaD_2 probable molybdopterin converting factor, small subunit 2 NP2500A 15 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 76802028 Nonpathogen - hypothetical protein NP2772A 1 None None None 76801921 Nonpathogen - probable transcription regulator NP2558A 5 COG2345 COG2345, Predicted transcriptional regulator Transcription 76801365 Nonpathogen - hypothetical protein NP1428A 12 COG2404 COG2404, Predicted phosphohydrolase (DHH superfamily) General function prediction only 76801241 Common - homolog 3 to S-adenosylmethionine-dependent methyltransferase 3 NP1178A 205 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 76801063 Common cinA_3 CinA-like domain protein 3 NP0822A 190 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 76801071 Common tp49_2 putative monovalent cation/H+ antiporter subunit G NP0838A 64 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 76803160 Common csp1_4 probable cold shock protein NP5064A 170 COG1278 CspC, Cold shock proteins Transcription 76801737 Common - predicted cell surface protein/ lipoprotein NP2186A 137 COG1520 COG1520, FOG: WD40-like repeat Function unknown 76802580 Nonpathogen - hypothetical protein NP3890A 2 None None None 76802489 Nonpathogen - hypothetical protein NP3706A 15 COG1873 COG1873, Uncharacterized conserved protein Function unknown 76801615 Common rtcB_2 RtcB-like protein 2 NP1934A 68 COG1690 RtcB, Uncharacterized conserved protein Function unknown 76801601 Common hbd_4 3-hydroxyacyl-CoA dehydrogenase 4 NP1906A 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 76800870 Common gcvT_2 homolog to aminomethyltransferase , glycin cleavage system T protein NP0436A 177 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 76802562 Nonpathogen - hypothetical protein NP3854A 4 None None None 76800847 Nonpathogen - hypothetical protein NP0386A 17 COG3357 COG3357, Predicted transcriptional regulator containing an HTH domain fused to a Zn-ribbon Transcription 76801508 Nonpathogen - homolog to stress response protein NP1718A 7 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 76802782 Common coxA_3 cytochrome-c-like terminal oxidase , subunit I 3 NP4296A 64 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 76801708 Common ftsZ_3 cell division protein NP2128A 54 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 76801665 Common ccdA cytochrome c-type biogenesis protein NP2040A 38 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 76803277 Common - conserved cobalamine operon protein NP5300A 29 COG1865 COG1865, Uncharacterized conserved protein Function unknown 76800952 Common - homolog 1 to Rieske iron sulfur protein NP0600A 16 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 76802449 Nonpathogen - hypothetical protein NP3622A 1 None None None 76801482 Common aspC_2 PLP-dependent aminotransferase (probable aspartate aminotransferase 2) NP1666A 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 76803294 Nonpathogen - hypothetical protein NP5334A 2 None None None 76801794 Nonpathogen - nuo cluster protein NP2302A 1 None None None 76803260 Common argE acetyl-lysine deacetylase NP5266A 120 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 76801044 Common - hypothetical protein NP0784A 37 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 76802431 Common - thioredoxin reductase homolog NP3586A 99 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 76801475 Nonpathogen - hypothetical protein NP1650A 1 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 76801694 Nonpathogen - conserved flagella cluster protein NP2100A 3 None None None 76800986 Nonpathogen - hypothetical protein NP0668A 3 None None None 76801305 Nonpathogen secG preprotein translocase subunit SecG NP1308A 4 COG4023 SBH1, Preprotein translocase subunit Sec61beta Intracellular trafficking and secretion 76801850 Common nadC nicotinate-nucleotide pyrophosphorylase (carboxylating) NP2414A 203 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 76803252 Nonpathogen - hypothetical protein NP5248A 1 None None None 76802190 Common mat S-adenosylmethionine synthetase NP3100A 43 COG1812 MetK, Archaeal S-adenosylmethionine synthetase Amino acid transport and metabolism 76802514 Nonpathogen glx_3 probable glutaredoxin NP3758A 6 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 76802569 Common - probable ATP-dependent helicase NP3868A 231 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 76800722 Nonpathogen - probable transcription regulator NP0134A 1 COG3355 COG3355, Predicted transcriptional regulator Transcription 76800945 Common mutS_3 DNA mismatch repair protein MutS homolog NP0586A 18 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 76801681 Nonpathogen - hypothetical protein NP2072A 6 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 76803116 Common cobO cob(I)alamin adenosyltransferase NP4974A 142 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 76802806 Nonpathogen pelA cell division protein pelota NP4344A 34 COG1537 PelA, Predicted RNA-binding proteins General function prediction only 76801761 Common - hypothetical protein NP2236A 50 COG2263 COG2263, Predicted RNA methylase Translation, ribosomal structure and biogenesis 76801558 Nonpathogen - hypothetical protein NP1820A 10 None None None 76800820 Common tp40_2 Kef-type transport system 1 (probable substrate potassium), subunit 2 NP0332A 195 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 76801209 Common cbiH_2 precorrin-3B C17-methyltransferase 2 NP1114A 188 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 76801983 Nonpathogen - hypothetical protein NP2682A 1 None None None 76802662 Nonpathogen - hypothetical protein NP4056A 1 COG4317 COG4317, Uncharacterized protein conserved in bacteria Function unknown 76800935 Common psp1 ribonuclease, PSP-type NP0566A 175 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 76802809 Common tatA_2 sec-independent protein translocase component TatA 2 NP4350A 36 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 76800678 Nonpathogen - hypothetical protein NP0046A 2 None None None 76800895 Nonpathogen - hypothetical protein NP0486A 3 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 76802403 Nonpathogen - hypothetical protein NP3530A 1 None None None 76803131 Common purU formyltetrahydrofolate deformylase NP5006A 224 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 76802243 Nonpathogen - conserved rps operon protein NP3206A 4 None None None 76803089 Common ferA_4 probable ferredoxin I 4 NP4918A 15 COG0633 Fdx, Ferredoxin Energy production and conversion 76800830 Nonpathogen - hypothetical protein NP0352A 30 COG1370 COG1370, Prefoldin, molecular chaperone implicated in de novo protein folding, alpha subunit Posttranslational modification, protein turnover, chaperones 76801684 Nonpathogen - hypothetical protein NP2080A 9 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 76801060 Nonpathogen - hypothetical protein NP0816A 2 None None None 76800819 Common tp40_1 Kef-type transport system 1 (probable substrate potassium), subunit 1 NP0330A 167 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 76802643 Nonpathogen - hypothetical protein NP4018A 3 None None None 76800973 Nonpathogen hop halorhodopsin NP0642A 7 COG5524 COG5524, Bacteriorhodopsin General function prediction only 76801869 Nonpathogen - conserved cox cluster protein NP2452A 4 None None None 76801156 Common - hypothetical protein NP1010A 60 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 76801590 Nonpathogen - diphthine synthase NP1884A 34 COG1798 DPH5, Diphthamide biosynthesis methyltransferase Translation, ribosomal structure and biogenesis 76802843 Common - homolog to transporter (probable substrate sulfate) NP4420A 18 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 76801021 Common cbiA cobyrinic acid a,c-diamide synthase NP0738A 136 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 76800835 Common - probable cell surface glycoprotein NP0362A 5 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 76801333 Nonpathogen - hypothetical protein NP1364A 1 None None None 76800855 Common - hypothetical protein NP0402A 126 COG0456 RimI, Acetyltransferases General function prediction only 76800964 Common leuA_2 2-isopropylmalate synthase 2, (R)-citramalate synthase NP0624A 211 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 76803312 Nonpathogen - hypothetical protein NP5370A 10 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 76800779 Common - predicted RIO-like serine/threonine protein kinase I NP0248A 61 COG0478 COG0478, RIO-like serine/threonine protein kinase fused to N-terminal HTH domain Signal transduction mechanisms 76801116 Nonpathogen - hypothetical protein NP0928A 2 None None None 76802087 Nonpathogen - hypothetical protein NP2890A 2 None None None 76801840 Common thiH_2 FO synthase subunit 2 NP2394A 81 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 76802669 Nonpathogen - hypothetical protein NP4070A 5 None None None 76803285 Nonpathogen - hypothetical protein NP5316A 3 None None None 76802920 Common - homolog 9 to S-adenosylmethionine-dependent methyltransferase 3 NP4574A 38 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 76802987 Nonpathogen - hypothetical protein NP4710A 1 None None None 76800739 Common abc09a2 ABC-type transport system ATP-binding protein II (probable substrates branched-chain/neutral amino acids) 5 NP0168A 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 76802329 Nonpathogen - hypothetical protein NP3382A 1 None None None 76802283 Nonpathogen - hypothetical protein NP3288A 1 None None None 76800877 Nonpathogen - hypothetical protein NP0450A 1 None None None 76800761 Common - helicase homolog NP0212A 126 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 76801191 Common hsp20_2 hsp20-type chaperone NP1078A 106 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 76803045 Common carA carbamoyl phosphate synthase small subunit NP4830A 234 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 76802265 Nonpathogen - hypothetical protein NP3250A 1 None None None 76803238 Common tp19 major facilitator family transporter 9 NP5220A 81 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 76802870 Nonpathogen - hypothetical protein NP4474A 4 None None None 76801124 Common cxp_1 predicted carboxypeptidase NP0944A 82 COG2317 COG2317, Zn-dependent carboxypeptidase Amino acid transport and metabolism 76801991 Common - probable stress response protein NP2698A 14 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 76802064 Nonpathogen rpoK DNA-directed RNA polymerase subunit K NP2844A 23 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 76802818 Common accA_2 biotin carboxylase 1, acyl-CoA carboxylase, alpha subunit 2 NP4368A 233 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 76800749 Common - signal-transducing histidine kinase; response regulator; PAS/PAC domain protein NP0188A 180 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76803201 Nonpathogen - hypothetical protein NP5146A 27 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 76800960 Nonpathogen - hypothetical protein NP0616A 1 None None None 76800667 Common crcB_2 protein crcB homolog 2 NP0024A 125 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 76801979 Common - hypothetical protein NP2674A 54 COG1808 COG1808, Predicted membrane protein Function unknown 76803150 Common hisS histidyl-tRNA synthetase NP5044A 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 76801220 Common - hydrolase (probable hydroxyacylglutathione hydrolase ) 5 NP1136A 92 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 76801359 Nonpathogen glx_2 probable glutaredoxin NP1416A 6 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 76802451 Common - homolog 5 to S-adenosylmethionine-dependent methyltransferase 3 NP3626A 17 None None None 76801133 Nonpathogen - homolog to predicted permease NP0962A 4 COG0628 PerM, Predicted permease General function prediction only 76801866 Common ctaB_1 heme O oxidase N-terminal domain homolog / protoheme IX farnesyltransferase NP2446A 166 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 76801149 Nonpathogen - hypothetical protein NP0996A 22 COG2412 COG2412, Uncharacterized conserved protein Function unknown 76802219 Common - hypothetical protein NP3158A 121 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 76802598 Nonpathogen abc12p ABC-type transport system permease protein (probable substrate copper) 2 NP3926A 2 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 76801327 Nonpathogen - probable transcription regulator NP1352A 7 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 76803259 Common argD acetylornithine aminotransferase NP5264A 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 76801783 Common thiL thiamin-phosphate kinase NP2280A 159 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 76802291 Nonpathogen - hypothetical protein NP3304A 1 None None None 76803031 Nonpathogen - homolog to glutamate-rich protein NP4802A 2 None None None 76802016 Nonpathogen - homolog to carbon starvation protein A NP2748A 1 None None None 76802770 Common - hypothetical protein NP4272A 53 COG3608 COG3608, Predicted deacylase General function prediction only 76802155 Nonpathogen - hypothetical protein NP3028A 5 None None None 76801203 Nonpathogen - cobalamin cluster protein NP1102A 5 COG4190 COG4190, Predicted transcriptional regulator Transcription 76801492 Common gabD2 succinic semialdehyde dehydrogenase NP1686A 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 76802946 Common - subtilisin-like serine protease NP4628A 128 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 76802167 Common nudF_2 ADP-ribose pyrophosphatase homolog NP3054A 138 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 76801394 Common htr35 transducer protein htr35 NP1486A 133 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 76802854 Nonpathogen - hypothetical protein NP4442A 1 None None None 76800681 Common moeB molybdenum cofactor biosynthesis protein MoeB NP0052A 223 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 76802269 Nonpathogen - hypothetical protein NP3260A 3 COG2512 COG2512, Uncharacterized membrane-associated protein/domain Function unknown 76802519 Nonpathogen - hypothetical protein NP3768A 28 COG1634 COG1634, Uncharacterized Rossmann fold enzyme General function prediction only 76800772 Nonpathogen - hypothetical protein NP0234A 1 None None None 76801252 Common abc26p ABC-type transport system permease protein (probable substrate copper) 4 NP1200A 27 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 76801520 Common ubiB_1 probable ubiquinone biosynthesis transmembrane protein 1 NP1742A 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 76801879 Common tp32 CBS-domain protein/ transporter 32 (probable substrate magnesium) NP2472A 168 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 76802147 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit beta NP3012A 109 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 76803091 Nonpathogen - hypothetical protein NP4922A 2 None None None 76802257 Nonpathogen - hypothetical protein NP3234A 2 None None None 76801667 Common - probable nitrate reductase / sulfite dehydrogenase (nitrate/ sulfite:cytochrome C oxidoreductase protein) NP2044A 107 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 76800901 Common mdhA malate dehydrogenase NP0498A 179 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 76801911 Common gbp1 translation-associated GTPase NP2538A 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 76801971 Nonpathogen - hypothetical protein NP2658A 2 None None None 76800750 Common - homolog 1 to phosphatidylglycerophosphatase NP0190A 10 None None None 76803078 Nonpathogen rpl30p 50S ribosomal protein L30P NP4896A 32 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 76801839 Common rnhB ribonuclease H II NP2392A 37 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 76802460 Common abc24a ABC-type transport system ATP-binding protein (probable substrates spermidine/putrescine/iron) 1 NP3648A 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 76802559 Common - hypothetical protein NP3848A 24 COG3372 COG3372, Uncharacterized conserved protein Function unknown 76802730 Nonpathogen - hypothetical protein NP4192A 11 COG4746 COG4746, Uncharacterized protein conserved in archaea Function unknown 76802467 Nonpathogen rps28e 30S ribosomal protein S28e NP3662A 33 COG2053 RPS28A, Ribosomal protein S28E/S33 Translation, ribosomal structure and biogenesis 76801638 Common abc14a ABC-type transport system ATP-binding protein (probable substrate phosphate) 1 NP1984A 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 76802104 Nonpathogen - hypothetical protein NP2926A 1 None None None 76801089 Common - ribonuclease R homolog NP0874A 191 COG0557 VacB, Exoribonuclease R Transcription 76802792 Nonpathogen - hypothetical protein NP4316A 9 COG1745 COG1745, Predicted metal-binding protein General function prediction only 76802990 Nonpathogen - hypothetical protein NP4716A 1 None None None 76803121 Nonpathogen - hypothetical protein NP4984A 14 COG1873 COG1873, Uncharacterized conserved protein Function unknown 76801345 Common trxB_2 thioredoxin reductase NP1388A 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 76800698 Nonpathogen - hypothetical protein NP0086A 17 COG1628 COG1628, Uncharacterized conserved protein Function unknown 76802737 Nonpathogen - hypothetical protein NP4206A 4 None None None 76801104 Nonpathogen - protein N-acetyltransferase homolog NP0904A 3 COG3153 COG3153, Predicted acetyltransferase General function prediction only 76800923 Nonpathogen tp53_2 predicted TRAP-type transport system protein NP0542A 8 COG4729 COG4729, Uncharacterized conserved protein Function unknown 76801167 Common atpB V-type ATP synthase subunit B NP1032A 247 COG1156 NtpB, Archaeal/vacuolar-type H+-ATPase subunit B Energy production and conversion 76803148 Common pepF oligoendopeptidase NP5040A 87 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 76802684 Common cinA_1 CinA-like domain protein 1 NP4100A 160 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 76801331 Common - hypothetical protein NP1360A 37 COG2520 COG2520, Predicted methyltransferase General function prediction only 76801233 Common - probable hydroxypyruvate reductase ; probable glycerate kinase NP1162A 86 COG2379 GckA, Putative glycerate kinase Carbohydrate transport and metabolism 76800928 Common - hypothetical protein NP0552A 28 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 76802169 Nonpathogen - probable transcription regulator NP3058A 4 None None None 76801654 Common ureE urease accessory protein UreE NP2018A 8 COG2371 UreE, Urease accessory protein UreE Posttranslational modification, protein turnover, chaperones 76801613 Nonpathogen - sugar metabolism cluster protein (homolog to quinone/ porphyrin-methyltransferase ) NP1930A 9 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 76801217 Nonpathogen - hypothetical protein NP1130A 9 None None None 76800975 Common tp07 stress response protein/ transporter 7 (probable substrates cationic amino acids) NP0646A 106 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 76802188 Nonpathogen cdc6_3 cell division control protein cdc6 homolog NP3096A 31 COG1474 CDC6, Cdc6-related protein, AAA superfamily ATPase DNA replication, recombination, and repair / Posttranslational modification, protein turnover, chaperones 76801870 Nonpathogen - conserved cox cluster protein NP2454A 1 None None None 76801262 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B NP1220A 210 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 76803126 Nonpathogen - hypothetical protein NP4994A 4 None None None 76801186 Common rfcC replication factor C small subunit 2 NP1068A 206 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 76801513 Nonpathogen - hypothetical protein NP1728A 14 COG3612 COG3612, Uncharacterized protein conserved in archaea Function unknown 76801940 Nonpathogen - hypothetical protein NP2596A 3 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 76802716 Common - hypothetical protein NP4164A 105 COG2936 COG2936, Predicted acyl esterases General function prediction only 76802405 Nonpathogen - homolog 2 to mannose-1-phosphate guanylyltransferase (GDP) NP3534A 4 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 76803315 Nonpathogen - hypothetical protein NP5376A 2 None None None 76801080 Nonpathogen - hypothetical protein NP0856A 4 None None None 76801340 Nonpathogen - hypothetical protein NP1378A 1 COG4307 COG4307, Uncharacterized protein conserved in bacteria Function unknown 76801578 Common htr26 transducer protein htr26 NP1860A 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 76801720 Nonpathogen - conserved flagella cluster protein NP2152A 3 None None None 76802200 Nonpathogen - hypothetical protein NP3120A 3 None None None 76802758 Common fadB_1 enoyl-CoA hydratase II 1 NP4248A 88 COG2030 MaoC, Acyl dehydratase Lipid metabolism 76802412 Common hypE_1 hydrogenase expression/ formation protein NP3548A 163 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 76803174 Nonpathogen - hypothetical protein NP5092A 3 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 76800865 Nonpathogen - hypothetical protein NP0426A 3 None None None 76801938 Nonpathogen - hypothetical protein NP2592A 1 None None None 76801759 Common - homolog 3 to phycocyanobilin lyase subunit NP2232A 21 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 76801883 Common - mandelate racemase homolog / muconate lactonizing enzyme homolog NP2480A 148 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 76802535 Nonpathogen - hypothetical protein NP3800A 3 None None None 76803017 Common gcvT aminomethyltransferase , glycin cleavage system T protein NP4774A 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 76802493 Nonpathogen tpiA_2 triosephosphate isomerase NP3716A 35 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 76802050 Common - hypothetical protein NP2816A 20 None None None 76800715 Common tp37 transporter 37 (probable substrates zinc/cadmium/cations) NP0120A 47 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 76802667 Common - hypothetical protein NP4066A 23 COG3372 COG3372, Uncharacterized conserved protein Function unknown 76802480 Nonpathogen - probable RNA-binding protein NP3688A 25 COG2888 COG2888, Predicted Zn-ribbon RNA-binding protein with a function in translation Translation, ribosomal structure and biogenesis 76800959 Nonpathogen - hypothetical protein NP0614A 4 None None None 76803157 Common - hypothetical protein NP5058A 40 COG3002 COG3002, Uncharacterized protein conserved in bacteria Function unknown 76801955 Common alkK_1 acyl-CoA synthetase II 1 (probable long-chain-fatty-acid--CoA ligase ) NP2626A 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 76801539 Common abc04p2_2 ABC-type transport system permease protein II 2 (probable substrates glutamine/glutamate/polar amino acids) NP1780A 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 76801752 Nonpathogen - hypothetical protein NP2218A 3 None None None 76802780 Nonpathogen - hypothetical protein NP4292A 1 None None None 76802061 Common rpl13p 50S ribosomal protein L13P NP2838A 126 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 76802033 Common - hypothetical protein NP2782A 36 COG3402 COG3402, Uncharacterized conserved protein Function unknown 76802327 Nonpathogen - hypothetical protein NP3378A 4 None None None 76800732 Nonpathogen - hypothetical protein NP0154A 3 None None None 76800768 Common - hypothetical protein NP0226A 7 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 76802863 Common glo_3 lyase/ dioxygenase 3 (probable lactoylglutathione lyase , aromatic compounds dioxygenase ) NP4460A 121 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 76802649 Nonpathogen tp21 major facilitator family transporter 11 (probable phosphoglycerate transporter) NP4030A 1 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 76800995 Nonpathogen priB DNA primase large subunit NP0686A 23 COG2219 PRI2, Eukaryotic-type DNA primase, large subunit DNA replication, recombination, and repair 76803185 Common - hypothetical protein NP5114A 20 COG3359 COG3359, Predicted exonuclease DNA replication, recombination, and repair 76801623 Nonpathogen - hypothetical protein NP1954A 2 None None None 76801705 Nonpathogen - hypothetical protein NP2122A 1 None None None 76802089 Common cbs_3 CBS domain protein 3 NP2894A 76 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 76801844 Nonpathogen - hypothetical protein NP2402A 4 None None None 76802925 Nonpathogen - hypothetical protein NP4584A 3 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 76803136 Common aor_4 aldehyde ferredoxin oxidoreductase 4 NP5016A 57 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 76800881 Nonpathogen - probable transcription regulator NP0458A 11 COG0640 ArsR, Predicted transcriptional regulators Transcription 76801530 Common - hypothetical protein NP1762A 26 COG0546 Gph, Predicted phosphatases General function prediction only 76801735 Nonpathogen tpiA_1 triosephosphate isomerase NP2182A 30 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 76801947 Common htr30 transducer protein htr30 NP2610A 153 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 76802975 Nonpathogen - hypothetical protein NP4686A 3 None None None 76801585 Nonpathogen - hypothetical protein NP1874A 1 None None None 76801324 Nonpathogen - hypothetical protein NP1346A 5 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 76802316 Common - signal-transducing histidine kinase NP3356A 7 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 76801173 Nonpathogen - hypothetical protein NP1044A 1 None None None 76802617 Common - hypothetical protein NP3966A 105 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 76801431 Nonpathogen - probable transcription regulator NP1562A 4 COG1339 COG1339, Transcriptional regulator of a riboflavin/FAD biosynthetic operon Transcription / Coenzyme metabolism 76803044 Common - transcription regulator NP4828A 102 COG1522 Lrp, Transcriptional regulators Transcription 76802305 Nonpathogen - hypothetical protein NP3332A 1 None None None 76802311 Common nrdA_2 ribonucleoside-diphosphate reductase , alpha subunit 2 NP3346A 219 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 76800827 Common dnaJ chaperone NP0346A 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 76801778 Common lysS lysine--tRNA ligase NP2270A 77 COG1384 LysS, Lysyl-tRNA synthetase (class I) Translation, ribosomal structure and biogenesis 76803266 Nonpathogen - hypothetical protein NP5278A 1 None None None 76803071 Nonpathogen rps14P 30S ribosomal protein S14P NP4882A 31 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 76802350 Common abc08s ABC-type transport system periplasmic substrate-binding protein (probable substrates branched-chain/neutral amino acids amide) 4 NP3424A 24 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 76802601 Common abc13a ABC-type transport system ATP-binding protein (probable substrate sulfate) 2 NP3932A 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 76801935 Common - probable anaerobic dehydrogenase subunit NP2586A 9 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 76801330 Nonpathogen - hypothetical protein NP1358A 32 COG1499 NMD3, NMD protein affecting ribosome stability and mRNA decay Translation, ribosomal structure and biogenesis 76800777 Common hypE_2 hydrogenase expression/formation protein NP0244A 66 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 76801418 Common mobB probable molybdopterin-guanine dinucleotide biosynthesis protein B NP1536A 91 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 76802002 Nonpathogen - hypothetical protein NP2720A 4 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 76802383 Nonpathogen - hypothetical protein NP3490A 5 COG2512 COG2512, Uncharacterized membrane-associated protein/domain Function unknown 76802116 Common - hypothetical protein NP2950A 22 None None None 76801521 Common hsp20_3 hsp20-type chaperone NP1744A 42 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 76801519 Common - translation elongation factor aEF-1 alpha subunit homolog NP1740A 249 COG5258 GTPBP1, GTPase General function prediction only 76802620 Common purD phosphoribosylamine--glycine ligase NP3972A 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 76801445 Nonpathogen - hypothetical protein NP1590A 5 None None None 76800888 Nonpathogen - hypothetical protein NP0472A 3 COG2411 COG2411, Uncharacterized conserved protein Function unknown 76802844 Nonpathogen - hypothetical protein NP4422A 1 None None None 76801599 Common - monooxygenase (homolog to alkanesulfonate monooxygenase) 2 NP1902A 74 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 76802549 Common nadE_1 NAD(+) synthase (glutamine-hydrolyzing) 1 NP3828A 236 COG0171 NadE, NAD synthase Coenzyme metabolism 76801407 Nonpathogen - hypothetical protein NP1514A 3 None None None 76801404 Common polB1 DNA-directed DNA polymerase (family B) NP1508A 60 COG0417 PolB, DNA polymerase elongation subunit (family B) DNA replication, recombination, and repair 76800726 Common - signal-transducing histidine kinase NP0142A 222 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 76802658 Nonpathogen - hypothetical protein NP4048A 4 COG4250 COG4250, Predicted sensor protein/domain Signal transduction mechanisms 76800795 Common metY_2 O-acetylhomoserine aminocarboxypropyltransferase 2, methionine synthase NP0280A 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 76802965 Nonpathogen - sugar metabolism cluster protein NP4666A 1 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 76801582 Nonpathogen - hypothetical protein NP1868A 3 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 76802704 Common abc05s ABC-type transport system periplasmic substrate-binding protein (probable substrates branched-chain/neutral amino acids amide) 1 NP4140A 121 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 76800999 Common pheT phenylalanyl-tRNA synthetase subunit beta NP0694A 233 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 76802677 Common - homolog 10 to S-adenosylmethionine-dependent methyltransferase 3 NP4086A 38 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 76802906 Common - IS1341-type transposase NP4546A 60 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 76802041 Nonpathogen abc23p_2 ABC-type transport system permease protein 2 NP2798A 7 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 76802578 Nonpathogen - hypothetical protein NP3886A 1 None None None 76801644 Common abc10a2 ABC-type transport system ATP-binding protein II (probable substrates urea/short chain-amides) NP1998A 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 76802358 Nonpathogen - hypothetical protein NP3440A 5 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 76802723 Nonpathogen - hypothetical protein NP4178A 1 None None None 76801575 Common ushA_1 5'-nucleotidase 1; 2',3'-cyclic-nucleotide 2'-phosphodiesterase 1; UDP-sugar hydrolase 1 NP1854A 135 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 76802421 Common - dehydrogenase/ reductase 1 NP3566A 201 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 76803203 Nonpathogen - homolog to predicted helicase NP5150A 19 COG1202 COG1202, Superfamily II helicase, archaea-specific General function prediction only 76802114 Nonpathogen - hypothetical protein NP2946A 4 None None None 76802102 Common folA dihydrofolate reductase NP2922A 146 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 76801425 Common - hypothetical protein NP1550A 21 COG4309 COG4309, Uncharacterized conserved protein Function unknown 76801555 Common - IS1341-type transposase NP1814A 39 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 76802223 Common trpC indole-3-glycerol-phosphate synthase NP3166A 220 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 76802471 Common metE_1 methionine synthase NP3670A 143 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 76802799 Common cbs_6 CBS domain protein 6 NP4330A 167 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 76802077 Common - hydrolase (probable hydroxyacylglutathione hydrolase ) 10 NP2870A 72 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 76802899 Nonpathogen - hypothetical protein NP4532A 5 None None None 76803066 Common rps17p 30S ribosomal protein S17P NP4872A 136 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 76803218 Nonpathogen - hypothetical protein NP5180A 1 None None None 76802823 Common birA2 biotin--[acetyl-CoA-carboxylase] ligase NP4378A 219 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 76802123 Common cbaB cytochrome-ba3 oxidase , subunit II NP2964A 47 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 76802347 Common - hypothetical protein NP3418A 46 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 76801729 Common cheR protein-glutamate O-methyltransferase NP2170A 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 76801058 Nonpathogen secE preprotein translocase subunit SecE NP0812A 3 COG2443 Sss1, Preprotein translocase subunit Sss1 Intracellular trafficking and secretion 76802740 Common amiE acylamide amidohydrolase NP4212A 119 COG0388 COG0388, Predicted amidohydrolase General function prediction only 76802694 Common trxA_4 thioredoxin NP4120A 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 76801766 Nonpathogen tfbA_3 transcription initiation factor TFB 3 NP2246A 34 COG1405 SUA7, Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB Transcription 76801914 Nonpathogen - hypothetical protein NP2544A 1 None None None 76802272 Common - hypothetical protein NP3266A 8 None None None 76801374 Nonpathogen - hypothetical protein NP1446A 1 None None None 76802811 Common sucD succinate--CoA ligase (ADP-forming) , alpha subunit NP4354A 211 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 76802478 Nonpathogen rpl21R 50S ribosomal protein L21e NP3684A 32 COG2139 RPL21A, Ribosomal protein L21E Translation, ribosomal structure and biogenesis 76802918 Common cysD sulfate adenylyltransferase , small subunit NP4570A 120 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 76802962 Common pmm_1 phosphohexomutase 1 (phosphoglucomutase , phosphomannomutase ) NP4660A 238 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 76801438 Common tp31 transporter 31/ TrkA-domain protein (NAD-binding protein) NP1576A 183 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 76802895 Common thrB homoserine kinase NP4524A 114 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism