Mycoplasma hyopneumoniae 7448, complete genome NC_007332 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 72080476 Common ldh L-lactate dehydrogenase MHP7448_0137 173 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 72080768 Common - hypothetical protein MHP7448_0435 110 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 72080606 Common - hypothetical protein MHP7448_0267 24 COG1323 COG1323, Predicted nucleotidyltransferase General function prediction only 72080700 Pathogen - hypothetical protein MHP7448_0364 1 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 72080954 Common - ABC transporter ATP-binding - Pr1-like MHP7448_0627 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 72080398 Common tsf elongation factor Ts MHP7448_0056 215 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 72080776 Common - hypothetical protein MHP7448_0444 2 None None None 72080868 Common - hypothetical protein MHP7448_0537 16 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 72080948 Pathogen - hypothetical protein MHP7448_0620 2 None None None 72080352 Common hrcA heat-inducible transcription repressor MHP7448_0010 146 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 72080579 Pathogen - hypothetical protein MHP7448_0240 1 None None None 72080780 Pathogen - hypothetical protein MHP7448_0448 1 None None None 72080567 Common - myo-inositol 2-dehydrogenase MHP7448_0228 178 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 72080591 Common - hypothetical protein MHP7448_0252 65 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 72080359 Pathogen - hypothetical protein MHP7448_0017 1 None None None 72080990 Pathogen - adhesin like-protein P146 MHP7448_0663 1 COG5309 COG5309, Exo-beta-1,3-glucanase Carbohydrate transport and metabolism 72080481 Pathogen - hypothetical protein MHP7448_0142 1 None None None 72080641 Common ugpQ glycerophosphoryl diester phosphodiesterase MHP7448_0303 123 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 72080462 Common rpmB 50S ribosomal protein L28 MHP7448_0122 39 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 72080531 Common rplW 50S ribosomal protein L23 MHP7448_0192 113 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 72080921 Common rnhB ribonuclease HII MHP7448_0593 19 COG1039 RnhC, Ribonuclease HIII DNA replication, recombination, and repair 72080739 Common ruvA Holliday junction DNA helicase motor protein MHP7448_0405 145 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 72080985 Pathogen rpmG 50S ribosomal protein L33 MHP7448_0658 1 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 72080910 Common dnaE DNA polymerase III DnaE MHP7448_0582 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 72080811 Pathogen - hypothetical protein MHP7448_0480 2 None None None 72080347 Common - putative MgpA like-protein MHP7448_0005 61 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 72080799 Pathogen - hypothetical protein MHP7448_0467 2 None None None 72080387 Common dinP DNA polymerase IV MHP7448_0045 180 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 72080848 Common glck glucokinase MHP7448_0517 135 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 72080622 Common topA DNA topoisomerase I MHP7448_0283 244 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 72080471 Common rplU 50S ribosomal protein L21 MHP7448_0131 211 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 72080364 Pathogen - hypothetical protein MHP7448_0022 1 None None None 72080557 Common - ISMHp1 transposase MHP7448_0218 30 COG5421 COG5421, Transposase DNA replication, recombination, and repair 72080435 Pathogen - hypothetical protein MHP7448_0093 1 None None None 72080934 Common - ABC transporter protein MHP7448_0606 127 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 72080721 Common proS prolyl-tRNA synthetase MHP7448_0385 210 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 72080717 Common - ABC transporter permease protein MHP7448_0381 2 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 72080511 Common infA translation initiation factor IF-1 MHP7448_0172 114 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 72080872 Common potB spermidine/putrescine ABC transporter permease protein MHP7448_0541 146 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 161611225 Common rplJ 50S ribosomal protein L10 MHP7448_0619 191 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 161611230 Common rpmI 50S ribosomal protein L35 MHP7448_0124 103 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 72080833 Common oppD-1 oligopeptide ABC transporter ATP binding protein MHP7448_0502 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 72080742 Pathogen - hypothetical protein MHP7448_0408 1 None None None 72080944 Common rpoC DNA-directed RNA polymerase subunit beta' MHP7448_0616 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 72080529 Common rpsS 30S ribosomal protein S19 MHP7448_0190 243 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 72080507 Common rpoA DNA-directed RNA polymerase subunit alpha MHP7448_0168 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 72080879 Common mtlF PTS system mannitol-specific component IIA MHP7448_0548 53 COG4668 MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain Carbohydrate transport and metabolism 72080423 Common - amino acid permease MHP7448_0081 22 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 72080510 Pathogen rpmJ 50S ribosomal protein L36 MHP7448_0171 1 None None None 72080500 Common deoB phosphopentomutase MHP7448_0161 70 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 72080445 Common rpsO 30S ribosomal protein S15 MHP7448_0103 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 72080898 Common - hypothetical protein MHP7448_0570 217 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 72080610 Pathogen - protein P102-like MHP7448_0271 1 None None None 72080706 Common - ABC transport permease protein MHP7448_0370 142 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 72080576 Pathogen - hypothetical protein MHP7448_0237 1 None None None 72080856 Pathogen - hypothetical protein MHP7448_0525 2 None None None 72080912 Common infB translation initiation factor IF-2 MHP7448_0584 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 72080886 Pathogen - hypothetical protein MHP7448_0555 1 None None None 72080714 Pathogen - lipoprotein MHP7448_0378 1 None None None 72080822 Pathogen - hypothetical protein MHP7448_0491 1 None None None 72080973 Common - hypothetical protein MHP7448_0646 21 COG3887 COG3887, Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain Signal transduction mechanisms 72080679 Pathogen - hypothetical protein MHP7448_0342 1 None None None 72080998 Pathogen - hypothetical protein MHP7448_0671 1 None None None 72080372 Pathogen - hypothetical protein MHP7448_0030 1 None None None 72080796 Common pepA leucyl aminopeptidase MHP7448_0464 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 72080384 Pathogen - hypothetical protein MHP7448_0042 1 None None None 72080589 Common eno phosphopyruvate hydratase MHP7448_0250 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 72081005 Common rpmH 50S ribosomal protein L34 MHP7448_0678 6 COG0230 RpmH, Ribosomal protein L34 Translation, ribosomal structure and biogenesis 72080838 Common pdhD dihydrolipoamide dehydrogenase MHP7448_0507 246 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 72080546 Common lysS lysyl-tRNA synthetase MHP7448_0207 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 72080650 Common - glycine cleavage system H protein MHP7448_0312 50 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 72080625 Common rpsP 30S ribosomal protein S16 MHP7448_0286 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 72080497 Common - hypothetical protein MHP7448_0158 100 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 72080883 Common ulaA ascorbate-specific PTS system enzyme IIC MHP7448_0552 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 72080747 Pathogen - putative ICEF-II MHP7448_0414 1 None None None 72080433 Common uvrA excinuclease ABC subunit A MHP7448_0091 243 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 72080806 Common - hypothetical protein MHP7448_0474 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 72080452 Pathogen - hypothetical protein MHP7448_0112 1 None None None 72080764 Common - hypothetical protein MHP7448_0431 15 COG1881 COG1881, Phospholipid-binding protein General function prediction only 72080908 Pathogen mnuA membrane nuclease, lipoprotein MHP7448_0580 2 COG2374 COG2374, Predicted extracellular nuclease General function prediction only 72080731 Pathogen - hypothetical protein MHP7448_0397 1 None None None 72080965 Pathogen rpmG 50S ribosomal protein L33 MHP7448_0638 1 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 72080385 Pathogen - hypothetical protein MHP7448_0043 1 None None None 72080485 Pathogen - chromate transport protein MHP7448_0146 1 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 72080598 Common tmk thymidylate kinase MHP7448_0259 228 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 72080813 Pathogen - hypothetical protein MHP7448_0482 2 None None None 72080790 Common rluD ribosomal large subunit pseudouridine synthase D MHP7448_0458 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 72080707 Common - ABC transporter permease protein MHP7448_0371 142 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 72080809 Common - hypothetical protein MHP7448_0477 78 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 72080406 Common - hypothetical protein MHP7448_0064 93 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 72080413 Common himA bacterial nucleoid DNA-binding protein MHP7448_0071 94 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 72080687 Common - hypothetical protein MHP7448_0351 20 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 72080771 Common ulaD 3-keto-L-gulonate-6-phosphate decarboxylase MHP7448_0438 54 COG0269 SgbH, 3-hexulose-6-phosphate synthase and related proteins Carbohydrate transport and metabolism 72080474 Common - hypothetical protein MHP7448_0135 4 COG1284 COG1284, Uncharacterized conserved protein Function unknown 72080778 Pathogen - hypothetical protein MHP7448_0446 1 None None None 72080379 Common vacB VACB-like ribonuclease II MHP7448_0037 192 COG0557 VacB, Exoribonuclease R Transcription 72080802 Pathogen - hypothetical protein MHP7448_0470 2 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 72080774 Pathogen - hypothetical protein MHP7448_0441 1 None None None 72080523 Common rplN 50S ribosomal protein L14 MHP7448_0184 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 72080680 Pathogen - hypothetical protein MHP7448_0344 1 None None None 72080928 Pathogen - hypothetical protein MHP7448_0600 1 None None None 72080354 Common argS arginyl-tRNA synthetase MHP7448_0012 248 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 72080399 Common ffh signal recognition particle protein MHP7448_0057 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 72080956 Pathogen - hypothetical protein MHP7448_0629 2 None None None 72080378 Pathogen - hypothetical protein MHP7448_0036 1 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 72080555 Pathogen - hypothetical protein MHP7448_0216 2 None None None 72080440 Common trxB thioredoxin reductase MHP7448_0098 247 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 72080620 Common pgsA CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase MHP7448_0281 155 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 72080449 Common gyrB DNA gyrase subunit B MHP7448_0109 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 72080513 Common adk adenylate kinase MHP7448_0174 231 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 72080362 Common - ABC transporter ATP-binding protein MHP7448_0020 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 161611227 Common rpsR 30S ribosomal protein S18 MHP7448_0294 214 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 72080831 Common - asparagine synthetase A MHP7448_0500 125 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 72080437 Common - hypothetical protein MHP7448_0095 3 COG4508 COG4508, Uncharacterized protein conserved in bacteria Function unknown 72080533 Common rplC 50S ribosomal protein L3 MHP7448_0194 249 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 72080460 Pathogen - hypothetical protein MHP7448_0120 1 None None None 72080550 Pathogen - hypothetical protein MHP7448_0211 1 None None None 72080923 Common pgm phosphoglyceromutase MHP7448_0595 126 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 72080737 Common pcrA ATP-dependent helicase PcrA MHP7448_0403 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 72080392 Common atpH ATP synthase delta chain MHP7448_0050 60 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 72080919 Common - PTS system glucose-specific enzyme IIB component MHP7448_0591 3 COG1264 PtsG, Phosphotransferase system IIB components Carbohydrate transport and metabolism 72080797 Common trmB tRNA (guanine-N(7))-methyltransferase MHP7448_0465 160 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 72080695 Common glpK glycerol kinase MHP7448_0359 178 COG0554 GlpK, Glycerol kinase Energy production and conversion 72081003 Common - putative inner membrane protein translocase component YidC MHP7448_0676 30 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 72080896 Pathogen - hypothetical protein MHP7448_0567 1 None None None 72080586 Common - TRSE-like protein MHP7448_0247 43 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 72080578 Pathogen - hypothetical protein MHP7448_0239 1 None None None 72080665 Pathogen - hypothetical protein MHP7448_0328 1 None None None 72080786 Common acpD acyl carrier protein phosphodiesterase MHP7448_0454 7 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 72080849 Pathogen - hypothetical protein MHP7448_0518 1 None None None 72080824 Pathogen - hypothetical protein MHP7448_0493 1 None None None 72080505 Common rluB ribosomal large subunit pseudouridine synthase B MHP7448_0166 205 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 72080421 Pathogen - hypothetical protein MHP7448_0079 1 None None None 72080604 Common - ABC transporter permease protein MHP7448_0265 42 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 72080349 Pathogen - hypothetical protein MHP7448_0007 1 COG3600 GepA, Uncharacterized phage-associated protein Function unknown 72080382 Common licA PTS system, lichenan-specific IIA component MHP7448_0040 17 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 72080933 Common - sugar ABC transporter ATP-binding protein MHP7448_0605 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 72080836 Pathogen - lipoprotein MHP7448_0505 1 None None None 72080983 Common - prolipoprotein p65 MHP7448_0656 3 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 72080810 Common atpA F0F1 ATP synthase subunit alpha MHP7448_0479 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 72080704 Pathogen - lipoprotein MHP7448_0368 1 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 72080943 Pathogen - hypothetical protein MHP7448_0615 2 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 72080656 Pathogen - hypothetical protein MHP7448_0319 1 None None None 72080623 Common rplS 50S ribosomal protein L19 MHP7448_0284 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 72080881 Common mtlA PTS system, mannitol-specific IIBC component MHP7448_0550 41 COG2213 MtlA, Phosphotransferase system, mannitol-specific IIBC component Carbohydrate transport and metabolism 72080450 Common - ISMHp1 transposase MHP7448_0110 30 COG5421 COG5421, Transposase DNA replication, recombination, and repair 72080458 Pathogen - hypothetical protein MHP7448_0118 1 None None None 72080842 Pathogen - hypothetical protein MHP7448_0511 1 None None None 72080761 Common tkt transketolase MHP7448_0428 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 72080495 Common era GTP-binding protein Era MHP7448_0156 217 COG1159 Era, GTPase General function prediction only 72080740 Common ruvB Holliday junction DNA helicase B MHP7448_0406 241 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 72080858 Common deoC deoxyribose-phosphate aldolase MHP7448_0527 137 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 72080992 Common - ABC transporter ATP-binding - Pr2 - like MHP7448_0665 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 72080677 Common - ABC transporter ATP-binding protein MHP7448_0340 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 72080670 Pathogen - lipoprotein MHP7448_0333 1 None None None 72080794 Pathogen - hypothetical protein MHP7448_0462 1 None None None 72080903 Common nagB glucosamine-6-phosphate deaminase MHP7448_0575 80 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 72080635 Pathogen - hypothetical protein MHP7448_0297 1 None None None 72080751 Pathogen - hypothetical protein MHP7448_0418 1 None None None 72080826 Common - ISMHp1 transposase MHP7448_0495 30 COG5421 COG5421, Transposase DNA replication, recombination, and repair 72080988 Pathogen - hypothetical protein MHP7448_0661 1 None None None 72080676 Common - hypothetical protein MHP7448_0339 3 None None None 72080355 Pathogen - hypothetical protein MHP7448_0013 1 COG3343 RpoE, DNA-directed RNA polymerase, delta subunit Transcription 72080447 Pathogen - protein P102 MHP7448_0107 1 None None None 72080561 Common nrdI ribonucleotide reductase stimulatory protein MHP7448_0222 37 COG1780 NrdI, Protein involved in ribonucleotide reduction Nucleotide transport and metabolism 72080631 Common ychF translation-associated GTPase MHP7448_0293 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 72080616 Common - hypothetical protein MHP7448_0277 81 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 72080645 Pathogen - hypothetical protein MHP7448_0307 1 None None None 72080682 Pathogen - hypothetical protein MHP7448_0346 1 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 72080607 Common mgtA cation-transporting P-type ATPase MHP7448_0268 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 72080614 Common rpmF 50S ribosomal protein L32 MHP7448_0275 79 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 72080893 Pathogen - hypothetical protein MHP7448_0563 1 None None None 72080553 Common oppD oligopeptide ABC transporter ATP-binding protein MHP7448_0214 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 72080343 Common dnaA chromosomal replication initiation protein MHP7448_0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 72080744 Pathogen - hypothetical protein MHP7448_0411 1 None None None 72080438 Common tpx thiol peroxidase MHP7448_0096 52 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 72080649 Common - hypothetical protein MHP7448_0311 13 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 72080520 Common rpsN 30S ribosomal protein S14 MHP7448_0181 143 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 72080443 Common clpB ATP-dependent protease binding protein MHP7448_0101 227 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 72080815 Pathogen - hypothetical protein MHP7448_0484 1 None None None 72080703 Pathogen - lipoprotein MHP7448_0367 1 None None None 72080654 Common - hypothetical protein MHP7448_0317 10 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 72080967 Common - tRNA/rRNA methyltransferase MHP7448_0640 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 72080890 Common - hypothetical protein MHP7448_0559 10 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 72080541 Common - hypothetical protein MHP7448_0202 121 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 72080729 Common - DNA methylase MHP7448_0395 103 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 72080516 Common rpsE 30S ribosomal protein S5 MHP7448_0177 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 72080367 Pathogen - hypothetical protein MHP7448_0025 1 None None None 72080788 Common rpmE 50S ribosomal protein L31 MHP7448_0456 103 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 72080430 Pathogen - hypothetical protein MHP7448_0088 1 None None None 72080930 Pathogen - hypothetical protein MHP7448_0602 1 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 72080844 Common - 46K surface antigen precursor MHP7448_0513 58 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 72080483 Common - putative tRNA/rRNA methyltransferase MHP7448_0144 133 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 72080769 Common araD L-ribulose-5-phosphate 4-epimerase MHP7448_0436 94 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 72080411 Common cmk cytidylate kinase MHP7448_0069 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 72080850 Pathogen - hypothetical protein MHP7448_0519 1 None None None 72080726 Common - S-adenosyl-methyltransferase MHP7448_0392 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 72080488 Common tig trigger factor MHP7448_0149 208 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 72080914 Common nusA transcription elongation factor NusA MHP7448_0586 218 COG0195 NusA, Transcription elongation factor Transcription 72080493 Common - DNA methylase MHP7448_0154 211 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 72080521 Common rplE 50S ribosomal protein L5 MHP7448_0182 248 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 72080974 Common leuS leucyl-tRNA synthetase MHP7448_0647 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 72080368 Common sipS signal peptidase I MHP7448_0026 134 COG4959 TraF, Type IV secretory pathway, protease TraF Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 72080861 Pathogen - hypothetical protein MHP7448_0530 1 None None None 72080874 Pathogen - hypothetical protein MHP7448_0543 1 None None None 72080602 Common - ABC transporter ATP-binding protein MHP7448_0263 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 72080857 Common upp uracil phosphoribosyltransferase MHP7448_0526 164 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 72080958 Pathogen plsC 1-acyl-sn-glycerol-3-phosphate acyltransferase MHP7448_0631 1 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 72080882 Common - hypothetical protein MHP7448_0551 3 COG1737 RpiR, Transcriptional regulators Transcription 72080469 Common - aminopeptidase MHP7448_0129 86 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 72080404 Common nfo endonuclease IV MHP7448_0062 98 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 72080376 Common parE topoisomerase IV subunit B MHP7448_0034 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 72080758 Pathogen - hypothetical protein MHP7448_0425 1 None None None 72080683 Pathogen - hypothetical protein MHP7448_0347 1 None None None 72080772 Pathogen - hypothetical protein MHP7448_0439 2 None None None 72080588 Common smf DNA processing protein SMF MHP7448_0249 139 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 72080689 Pathogen - P60-like lipoprotein MHP7448_0353 1 None None None 72080936 Common tdk thymidine kinase MHP7448_0608 96 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 72080953 Common - hypothetical protein MHP7448_0626 107 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 72080674 Pathogen - hypothetical protein MHP7448_0337 1 None None None 72080633 Common ssb single-strand binding protein MHP7448_0295 33 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 72080851 Pathogen - hypothetical protein MHP7448_0520 1 None None None 72080394 Common atpG ATP synthase gamma chain MHP7448_0052 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 72080859 Common gyrA DNA gyrase subunit A MHP7448_0528 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 72080628 Pathogen - hypothetical protein MHP7448_0289 1 None None None 72080380 Common cls cardiolipin synthetase MHP7448_0038 142 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 72080792 Common rplK 50S ribosomal protein L11 MHP7448_0460 247 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 72080994 Pathogen - hypothetical protein MHP7448_0667 1 None None None 72081001 Pathogen - hypothetical protein MHP7448_0674 1 None None None 72080456 Common pdhB pyruvate dehydrogenase MHP7448_0116 196 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 72080735 Common asnC asparaginyl-tRNA synthetase MHP7448_0401 246 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 161611231 Common secA preprotein translocase subunit SecA MHP7448_0086 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 72080828 Pathogen - p76 membrane protein precursor MHP7448_0497 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 72080369 Pathogen gatC Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit MHP7448_0027 1 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 72080573 Common rbsB periplasmic sugar-binding proteins MHP7448_0234 90 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 72080875 Pathogen - hypothetical protein MHP7448_0544 1 None None None 72080784 Common - ABC transporter ATP-binding protein MHP7448_0452 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 72080711 Common - PTS system enzyme IIB component MHP7448_0375 34 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 72080543 Common pth peptidyl-tRNA hydrolase MHP7448_0204 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 72080503 Common nifS nitrogen fixation protein MHP7448_0164 227 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 72080905 Common rpiB ribose-5-phosphate isomerase B MHP7448_0577 126 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 72080803 Common - hypothetical protein MHP7448_0471 20 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 72080839 Common ackA acetate kinase MHP7448_0508 161 COG0282 ackA, Acetate kinase Energy production and conversion 72080702 Pathogen - lipoprotein MHP7448_0366 1 None None None 72080479 Common hemK protoporphirogen oxidase MHP7448_0140 176 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 72080941 Pathogen - hypothetical protein MHP7448_0613 1 None None None 72080746 Pathogen - hypothetical protein MHP7448_0413 1 None None None 72080563 Common glyA serine hydroxymethyltransferase MHP7448_0224 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 72080441 Pathogen - outer membrane protein - P95 MHP7448_0099 1 None None None 72080600 Common - hypothetical protein MHP7448_0261 202 COG0313 COG0313, Predicted methyltransferases General function prediction only 72080357 Common rluC ribosomal large subunit pseudouridine synthase C MHP7448_0015 195 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 72080639 Pathogen - hypothetical protein MHP7448_0301 1 None None None 72080432 Pathogen - hypothetical protein MHP7448_0090 1 None None None 72080870 Pathogen - hypothetical protein MHP7448_0539 2 None None None 72080418 Common rpsG 30S ribosomal protein S7 MHP7448_0076 242 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 72080698 Pathogen - ABC transport system permease protein p69 - like MHP7448_0362 1 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 72080939 Pathogen - hypothetical protein MHP7448_0611 3 None None None 72080551 Common oppB-1 oligopeptide ABC transporter system permease MHP7448_0212 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 72080530 Common rplB 50S ribosomal protein L2 MHP7448_0191 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 72080408 Common uvrC excinuclease ABC subunit C MHP7448_0066 224 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 72080547 Common - hydrolase of the HAD family MHP7448_0208 92 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 72080647 Common baiH NADH-dependent flavin oxidoreductase MHP7448_0309 177 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 72080540 Common alaS alanyl-tRNA synthetase MHP7448_0201 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 72080518 Common rplF 50S ribosomal protein L6 MHP7448_0179 243 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 72080345 Common gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA MHP7448_0003 192 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 72080724 Pathogen - hypothetical protein MHP7448_0390 1 None None None 72080643 Common - ABC transporter ATP-binding protein MHP7448_0305 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 72080350 Common ftsY cell division protein ftsY MHP7448_0008 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 72080593 Common lplA lipoate-protein ligase A MHP7448_0254 72 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 72080402 Common rpoD RNA polymerase sigma factor RpoD MHP7448_0060 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 72080748 Pathogen - putative ICEF Integrative Conjugal Element - II MHP7448_0415 1 None None None 72080467 Common - hypothetical protein MHP7448_0127 12 None None None 72080691 Pathogen - hypothetical protein MHP7448_0355 1 None None None 72080756 Common - putative ICEF-IIA MHP7448_0423 49 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 72080685 Pathogen - hypothetical protein MHP7448_0349 1 None None None 72080537 Common - protein P97 MHP7448_0198 2 COG3147 DedD, Uncharacterized protein conserved in bacteria Function unknown 72080770 Common sgaU L-xylulose 5-phosphate 3-epimerase MHP7448_0437 21 COG3623 SgaU, Putative L-xylulose-5-phosphate 3-epimerase Carbohydrate transport and metabolism 72080732 Common rnc ribonuclease III MHP7448_0398 190 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 72080611 Common - protein P97-like MHP7448_0272 10 None None None 72080863 Common polC DNA polymerase III PolC MHP7448_0532 213 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 72080979 Common ksgA dimethyladenosine transferase MHP7448_0652 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 72080781 Common - GTPase EngB MHP7448_0449 194 COG0218 COG0218, Predicted GTPase General function prediction only 72080473 Common lip2 lipase-esterase MHP7448_0133 62 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 72080916 Common glpD glycerol-3-phosphate dehydrogenase MHP7448_0588 45 COG0579 COG0579, Predicted dehydrogenase General function prediction only 72080389 Common atpB F0F1 ATP synthase subunit A MHP7448_0047 14 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 72080569 Common iolE myo-inositol catabolism protein MHP7448_0230 63 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 72080486 Pathogen - hypothetical protein MHP7448_0147 2 None None None 72080718 Common - proline dipeptidase MHP7448_0382 25 COG1739 COG1739, Uncharacterized conserved protein Function unknown 72080480 Common gltX glutamyl-tRNA synthetase MHP7448_0141 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 72080754 Pathogen - hypothetical protein MHP7448_0421 1 None None None 72080987 Pathogen - hypothetical protein MHP7448_0660 1 None None None 72080960 Common scpB segregation and condensation protein B MHP7448_0633 141 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 72080976 Common - hypothetical protein MHP7448_0649 10 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 72080429 Common rbgA ribosomal biogenesis GTPase MHP7448_0087 85 COG1161 COG1161, Predicted GTPases General function prediction only 72080499 Common - ABC transporter ATP-binding and permease protein MHP7448_0160 236 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 72080395 Common atpD F0F1 ATP synthase subunit beta MHP7448_0053 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 72080426 Common deoD purine-nucleoside phosphorylase MHP7448_0084 77 COG0813 DeoD, Purine-nucleoside phosphorylase Nucleotide transport and metabolism 72080733 Pathogen - hypothetical protein MHP7448_0399 1 None None None 72080765 Common - hypothetical protein MHP7448_0432 2 None None None 72080454 Common apt adenine phosphoribosyltransferase MHP7448_0114 186 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 72080900 Common nagA N-acetylglucosamine-6-phosphate deacetylase MHP7448_0572 108 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 72080657 Pathogen - hypothetical protein MHP7448_0320 1 None None None 72080829 Pathogen - hypothetical protein MHP7448_0498 1 None None None 72080996 Common - hypothetical protein MHP7448_0669 43 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 72080491 Common - hypothetical protein MHP7448_0152 157 COG1162 COG1162, Predicted GTPases General function prediction only 72080907 Pathogen - hypothetical protein MHP7448_0579 2 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 72080853 Pathogen - hypothetical protein MHP7448_0522 2 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 72080817 Common - hypothetical protein MHP7448_0486 2 None None None 72080969 Common - hypothetical protein MHP7448_0642 69 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 72080888 Common - d-ribulose-5-phosphate 3 epimerase MHP7448_0557 55 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 72080891 Pathogen - hypothetical protein MHP7448_0560 1 None None None 72080566 Common iolB myo-inositol catabolism protein MHP7448_0227 10 COG3718 IolB, Uncharacterized enzyme involved in inositol metabolism Carbohydrate transport and metabolism 72080416 Pathogen - hypothetical protein MHP7448_0074 1 None None None 72080360 Pathogen - hypothetical protein MHP7448_0018 1 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 72080582 Common aspS aspartyl-tRNA synthetase MHP7448_0243 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 72080661 Pathogen - hypothetical protein MHP7448_0324 1 None None None 72080727 Common ftsZ cell division protein ftsZ MHP7448_0393 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 72080877 Common ktrB potassium uptake protein MHP7448_0546 86 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 72080709 Pathogen - hypothetical protein MHP7448_0373 3 None None None 72080668 Pathogen - hypothetical protein MHP7448_0331 1 None None None 72080866 Common pyrH uridylate kinase MHP7448_0535 234 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 72080924 Pathogen - hypothetical protein MHP7448_0596 1 None None None 72080501 Common - hypothetical protein MHP7448_0162 7 COG0781 NusB, Transcription termination factor Transcription 72080585 Common - hypothetical protein MHP7448_0246 4 None None None 72080926 Pathogen - hypothetical protein MHP7448_0598 1 None None None 72080935 Common - sugar ABC transporter permease protein MHP7448_0607 107 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 72080715 Common - ABC transport ATP-binding protein MHP7448_0379 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 72080640 Common - permease MHP7448_0302 13 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 72080741 Common - hypothetical protein MHP7448_0407 8 None None None 72080722 Pathogen - hypothetical protein MHP7448_0387 2 None None None 72080525 Common rpmC 50S ribosomal protein L29 MHP7448_0186 21 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 72080885 Common - PTS system enzyme IIA component MHP7448_0554 20 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 72080651 Pathogen - hypothetical protein MHP7448_0313 1 None None None 72080575 Common - transposase MHP7448_0236 30 COG5421 COG5421, Transposase DNA replication, recombination, and repair 72080465 Common infC Translation initiation factor IF-3 MHP7448_0125 208 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 72080414 Pathogen - hypothetical protein MHP7448_0072 1 None None None 72080570 Common mglA ribose ABC transport ATP-binding protein MHP7448_0231 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 72080509 Common rpsM 30S ribosomal protein S13 MHP7448_0170 230 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 72080897 Pathogen - hypothetical protein MHP7448_0569 1 None None None 72080991 Common - ABC transporter ATP-binding - Pr1 MHP7448_0664 246 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 72080902 Common - PTS system, N-acetylglucosamine-specific II ABC component MHP7448_0574 49 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 72080453 Common - amino acid permease MHP7448_0113 9 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 72080371 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B MHP7448_0029 213 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 72080552 Common oppC-1 oligopeptide transport system permease protein MHP7448_0213 212 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 72080795 Common - hypothetical protein MHP7448_0463 3 None None None 72080666 Pathogen - hypothetical protein MHP7448_0329 1 None None None 72080949 Pathogen - lipoprotein MHP7448_0621 2 None None None 72080671 Pathogen - hypothetical protein MHP7448_0334 1 None None None 72080678 Pathogen - hypothetical protein MHP7448_0341 1 None None None 72080999 Common valS valyl-tRNA synthetase MHP7448_0672 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 72080750 Pathogen - hypothetical protein MHP7448_0417 1 None None None 72080970 Common - hemolysin C MHP7448_0643 186 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 72080496 Common cdd cytidine deaminase MHP7448_0157 107 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 72080618 Common - transcriptional regulator MHP7448_0279 19 COG1737 RpiR, Transcriptional regulators Transcription 72080762 Pathogen - hypothetical protein MHP7448_0429 1 None None None 72080779 Pathogen - hypothetical protein MHP7448_0447 1 None None None 72080763 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase MHP7448_0430 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 72080909 Common - 5'-3' exonuclease MHP7448_0581 216 COG0258 Exo, 5'-3' exonuclease (including N-terminal domain of PolI) DNA replication, recombination, and repair 72080545 Common ftsH cell division protein MHP7448_0206 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 72080446 Pathogen - hypothetical protein MHP7448_0106 1 None None None 72080837 Common pdhC dihydrolipoamide acetyltransferase MHP7448_0506 194 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 72080820 Pathogen - hypothetical protein MHP7448_0489 1 None None None 72080982 Common gidB glucose-inhibited division protein B MHP7448_0655 144 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 72080383 Common obgE GTPase ObgE MHP7448_0041 248 COG0536 Obg, Predicted GTPase General function prediction only 72080590 Common serS seryl-tRNA synthetase MHP7448_0251 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 72080738 Pathogen - hypothetical protein MHP7448_0404 1 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 72080775 Pathogen - hypothetical protein MHP7448_0443 1 None None None 72080918 Common trpS tryptophanyl-tRNA synthetase MHP7448_0590 231 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 72080955 Common - ABC transporter ATP-binding - Pr2 - like MHP7448_0628 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 72080723 Common - type III restriction-modification system: methylase MHP7448_0388 72 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 72080484 Common - chromate transport protein MHP7448_0145 27 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 72080834 Common oppC oligopeptide transport system permease protein MHP7448_0503 200 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 72080477 Pathogen - hypothetical protein MHP7448_0138 2 None None None 72080605 Common lig DNA ligase MHP7448_0266 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 72080407 Pathogen - hypothetical protein MHP7448_0065 2 None None None 72080571 Pathogen - hypothetical protein MHP7448_0232 1 None None None 72080807 Common pfs 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase MHP7448_0475 4 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 72080708 Pathogen - Lppt protein MHP7448_0372 1 None None None 72080388 Pathogen - hypothetical protein MHP7448_0046 1 None None None 72080929 Common - hypothetical protein MHP7448_0601 28 COG1481 COG1481, Uncharacterized protein conserved in bacteria Function unknown 72080373 Pathogen lsp lipoprotein signal peptidase MHP7448_0031 1 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 72080615 Common truB tRNA pseudouridine synthase B MHP7448_0276 231 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 72080400 Common glyS glycyl-tRNA synthetase MHP7448_0058 97 COG0423 GRS1, Glycyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 72080584 Common rpsT 30S ribosomal protein S20 MHP7448_0245 49 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 72080568 Common iolD myo-inositol catabolism protein MHP7448_0229 220 COG3962 COG3962, Acetolactate synthase Amino acid transport and metabolism 72080730 Common metG methionyl-tRNA synthetase MHP7448_0396 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 72080597 Common recR recombination protein RecR MHP7448_0258 203 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 72080592 Common lip triacylglycerol lipase MHP7448_0253 23 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 72080812 Pathogen - hypothetical protein MHP7448_0481 1 None None None 72080984 Common - ABC transporter ATP-binding protein P115-like MHP7448_0657 192 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 72080637 Pathogen - hypothetical protein MHP7448_0299 1 None None None 72080390 Common atpE F0F1 ATP synthase subunit C MHP7448_0048 89 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 72080351 Common - hypothetical protein MHP7448_0009 164 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 72080532 Common rplD 50S ribosomal protein L4 MHP7448_0193 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 72080524 Common rpsQ 30S ribosomal protein S17 MHP7448_0185 204 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 72080920 Common - ATP binding protein MHP7448_0592 74 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 72080348 Common - DHH family phosphoesterase MHP7448_0006 73 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 72080962 Common gcp O-sialoglycoprotein endopeptidase MHP7448_0635 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 72080819 Common - hypothetical protein MHP7448_0488 66 COG1624 COG1624, Uncharacterized conserved protein Function unknown 161611226 Common nadD putative nicotinate-nucleotide adenylyltransferase MHP7448_0476 191 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 72080845 Common xylG xylose ABC transporter ATP-binding protein MHP7448_0514 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 72080558 Pathogen - hypothetical protein MHP7448_0219 1 None None None 72080642 Common - hypothetical protein MHP7448_0304 201 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 72080621 Pathogen - hypothetical protein MHP7448_0282 1 None None None 72080397 Common rpsB 30S ribosomal protein S2 MHP7448_0055 242 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 72080871 Common potC spermidine/putrescine ABC transporter permease protein MHP7448_0540 20 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 72080911 Pathogen rbfA ribosome-binding factor A MHP7448_0583 1 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 72080424 Common nox NADH oxidase MHP7448_0082 200 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 72080434 Common - hypothetical protein MHP7448_0092 151 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 72080420 Pathogen - hypothetical protein MHP7448_0078 1 None None None 72080705 Common - ABC transporter permease protein MHP7448_0369 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 72080577 Pathogen - hypothetical protein MHP7448_0238 1 None None None 72080393 Common atpA-1 F0F1 ATP synthase subunit alpha MHP7448_0051 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 72080736 Pathogen - hypothetical protein MHP7448_0402 1 None None None 72080793 Pathogen - hypothetical protein MHP7448_0461 1 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 72080895 Pathogen - hypothetical protein MHP7448_0566 1 None None None 72080696 Pathogen - P37-like ABC transporter substrate-binding lipoprotein MHP7448_0360 1 None None None 72080506 Common rplQ 50S ribosomal protein L17 MHP7448_0167 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 72080549 Common - ABC transporter ATP-binding protein MHP7448_0210 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 72080904 Common rpsD 30S ribosomal protein S4 MHP7448_0576 227 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 72080713 Common - hypothetical protein MHP7448_0377 35 COG1735 Php, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 72080664 Common - hypothetical protein MHP7448_0327 45 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 72080785 Common - ABC transporter permease protein MHP7448_0453 3 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 72080945 Common rpoB DNA-directed RNA polymerase subunit beta MHP7448_0617 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 72080980 Common - hypothetical protein MHP7448_0653 234 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 72080942 Common ddem cytosine specific DNA methyltransferase MHP7448_0614 123 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 72080659 Common - transposase MHP7448_0322 38 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 72080624 Common trmD tRNA (guanine-N1)-methyltransferase MHP7448_0285 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 72080760 Common efp elongation factor P MHP7448_0427 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 72080564 Common - methylmalonate-semialdehyde dehydrogenase MHP7448_0225 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 72080494 Common - hypothetical protein MHP7448_0155 3 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 72080889 Pathogen - hypothetical protein MHP7448_0558 1 None None None 72080841 Pathogen - hypothetical protein MHP7448_0510 1 None None None 72080835 Common oppB oligopeptide ABC transporter permease protein MHP7448_0504 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 72080855 Common lon heat shock ATP-dependent protease MHP7448_0524 209 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 72080932 Common xylF ABC transporter xylose-binding lipoprotein MHP7448_0604 26 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 72080381 Common recA recombinase A MHP7448_0039 241 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 72080559 Pathogen - hypothetical protein MHP7448_0220 1 None None None 72080951 Common - ABC transporter ATP-binding - Pr1 MHP7448_0623 169 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 72080993 Pathogen - hypothetical protein MHP7448_0666 1 None None None 72080609 Common - nuclease, lipoprotein MHP7448_0270 15 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 72080544 Common - hypothetical protein MHP7448_0205 86 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 72080972 Common rplI 50S ribosomal protein L9 MHP7448_0645 6 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 72080821 Common pgk phosphoglycerate kinase MHP7448_0490 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 72081004 Common rnpA ribonuclease P protein component MHP7448_0677 16 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 72080459 Pathogen - hypothetical protein MHP7448_0119 2 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 72080439 Common lgt prolipoprotein diacylglyceryl transferase MHP7448_0097 132 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 72080636 Pathogen - hypothetical protein MHP7448_0298 1 None None None 72080675 Pathogen - hypothetical protein MHP7448_0338 1 None None None 72080989 Pathogen - hypothetical protein MHP7448_0662 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 72080752 Common - hypothetical protein MHP7448_0419 2 None None None 72080613 Common pheT phenylalanyl-tRNA synthetase subunit beta MHP7448_0274 124 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 72080356 Common fba fructose-bisphosphate aldolase MHP7448_0014 176 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 72080867 Pathogen - hypothetical protein MHP7448_0536 1 None None None 72080801 Common - ABC transporter atp-binding protein MHP7448_0469 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 72080539 Common - hypothetical protein MHP7448_0200 189 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 72080777 Pathogen - hypothetical protein MHP7448_0445 1 None None None 72080562 Common nrdF ribonucleotide-diphosphate reductase subunit beta MHP7448_0223 75 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 72080773 Pathogen - hypothetical protein MHP7448_0440 1 COG4372 COG4372, Uncharacterized protein conserved in bacteria with the myosin-like domain Function unknown 72080386 Pathogen - hypothetical protein MHP7448_0044 1 None None None 72080412 Common engA GTP-binding protein EngA MHP7448_0070 226 COG1160 COG1160, Predicted GTPases General function prediction only 72080884 Common - PTS system galactitol-specific enzyme IIB component MHP7448_0553 6 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 72080595 Common dnaX DNA polymerase III subunits gamma and tau MHP7448_0256 249 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 72080894 Pathogen - hypothetical protein MHP7448_0564 1 None None None 72080451 Common pfkA 6-phosphofructokinase MHP7448_0111 144 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 72080860 Common pmsR methionine sulfoxide reductase B MHP7448_0529 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 72080880 Common mtlD mannitol-1-phosphate 5-dehydrogenase MHP7448_0549 36 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 72080475 Common - hexosephosphate transport protein MHP7448_0136 10 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 72080688 Pathogen - hypothetical protein MHP7448_0352 1 None None None 72080957 Common - 5'-nucleotidase precursor MHP7448_0630 132 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 72080767 Pathogen - hypothetical protein MHP7448_0434 1 None None None 72080913 Common - hypothetical protein MHP7448_0585 7 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 72080363 Common - ABC transporter ATP-binding protein MHP7448_0021 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 72080522 Common rplX 50S ribosomal protein L24 MHP7448_0183 185 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 72080832 Common oppF oligopeptide ABC transporter ATP-binding protein MHP7448_0501 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 161611228 Common pyrG CTP synthetase MHP7448_0280 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 72080603 Common - ABC transporter ATP-binding protein MHP7448_0264 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 72080720 Common - thioredoxin MHP7448_0384 25 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 72080694 Common glpF glycerol uptake facilitator protein MHP7448_0358 85 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 72080847 Pathogen - hypothetical protein MHP7448_0516 1 None None None 72080353 Common grpE heat shock protein MHP7448_0011 49 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 72080482 Common - tRNA/rRNA methyltransferase MHP7448_0143 133 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 72080789 Common napA neutrophil activating factor MHP7448_0457 32 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 72080873 Common potA spermidine/putrescine ABC transporter ATP-binding MHP7448_0542 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 72080436 Common - hypothetical protein MHP7448_0094 19 COG4487 COG4487, Uncharacterized protein conserved in bacteria Function unknown 72080556 Common - lipoprotein MHP7448_0217 7 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 72080840 Common eutD phosphotransacetylase MHP7448_0509 164 COG0280 Pta, Phosphotransacetylase Energy production and conversion 72080370 Common gatA amidase MHP7448_0028 218 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 72080512 Common map methionine aminopeptidase MHP7448_0173 249 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 72080422 Pathogen - hypothetical protein MHP7448_0080 1 None None None 72080798 Pathogen - hypothetical protein MHP7448_0466 1 None None None 72080448 Pathogen - protein P97 MHP7448_0108 1 None None None 72080391 Pathogen atpF ATP synthase subunit B MHP7448_0049 1 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 72080922 Common - hypothetical protein MHP7448_0594 12 COG3763 COG3763, Uncharacterized protein conserved in bacteria Function unknown 72080681 Pathogen - hypothetical protein MHP7448_0345 1 None None None 72080405 Common tyrS tyrosyl tRNA synthetase MHP7448_0063 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 72080463 Common rplT 50S ribosomal protein L20 MHP7448_0123 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 72080814 Pathogen - hypothetical protein MHP7448_0483 1 None None None 72080534 Common rpsJ 30S ribosomal protein S10 MHP7448_0195 218 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 72080508 Common rpsK 30S ribosomal protein S11 MHP7448_0169 236 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 72080535 Pathogen - hypothetical protein MHP7448_0196 1 None None None 72080852 Common pepF oligoendopeptidase F MHP7448_0521 83 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 72080766 Pathogen - hypothetical protein MHP7448_0433 1 COG4547 CobT, Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase) Coenzyme metabolism 72080468 Pathogen - hypothetical protein MHP7448_0128 1 None None None 72080906 Common fpg formamidopyrimidine-DNA glycosylase MHP7448_0578 182 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 72080952 Common - ABC transporter ATP-binding protein - Pr2 MHP7448_0624 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 72080634 Common rpsF 30S ribosomal protein S6 MHP7448_0296 4 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 72080630 Common - putative type II DNA modification enzyme: methyltransferase MHP7448_0291 35 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 72080804 Common ptsI phosphoenolpyruvate-protein phosphotransferase MHP7448_0472 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 72080461 Pathogen - hypothetical protein MHP7448_0121 1 None None None 72080673 Pathogen - hypothetical protein MHP7448_0336 1 None None None 72080492 Common gmk guanylate kinase MHP7448_0153 213 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 72080975 Common uvrB excinuclease ABC subunit B MHP7448_0648 231 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 72080995 Common greA transcription elongation factor MHP7448_0668 203 COG0782 GreA, Transcription elongation factor Transcription 72080457 Pathogen - hypothetical protein MHP7448_0117 1 None None None 72080986 Common pepP XAA-PRO aminopeptidase MHP7448_0659 248 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 72080961 Common - hypothetical protein MHP7448_0634 3 COG0392 COG0392, Predicted integral membrane protein Function unknown 72080892 Pathogen - hypothetical protein MHP7448_0561 1 None None None 72080658 Common - hypothetical protein MHP7448_0321 77 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 72080899 Common pdhD-1 dihydrolipoamide dehydrogenase MHP7448_0571 247 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 72080745 Pathogen - hypothetical protein MHP7448_0412 1 None None None 72080542 Pathogen - hypothetical protein MHP7448_0203 1 None None None 72080504 Common - hypothetical protein MHP7448_0165 3 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 72080876 Common ktrA potassium uptake protein MHP7448_0545 143 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 72080629 Pathogen - hypothetical protein MHP7448_0290 1 None None None 72080655 Pathogen - hypothetical protein MHP7448_0318 1 None None None 72080712 Common ulaA ascorbate-specific PTS system enzyme IIC MHP7448_0376 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 72080783 Common metK S-adenosylmethionine synthetase MHP7448_0451 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 72080823 Common fruA PTS system, fructose-specific IIABC component MHP7448_0492 83 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 72080581 Common hisS histidyl-tRNA synthetase MHP7448_0242 242 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 72080966 Pathogen - hypothetical protein MHP7448_0639 1 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 72080940 Pathogen - hypothetical protein MHP7448_0612 2 COG2433 COG2433, Uncharacterized conserved protein Function unknown 72080478 Common prfA peptide chain release factor 1 MHP7448_0139 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 72080693 Common - amino acid permease MHP7448_0357 56 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 72080734 Pathogen - hypothetical protein MHP7448_0400 1 None None None 72081002 Common - hypothetical protein MHP7448_0675 10 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 72080669 Common - subtilisin-like serine protease MHP7448_0332 3 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 72080427 Pathogen - hypothetical protein MHP7448_0085 1 None None None 72080572 Common - putative ribose ABC transporter MHP7448_0233 111 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 72080825 Common - mannose-6-phosphate isomerase MHP7448_0494 48 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 72080753 Common - single-strand binding protein MHP7448_0420 5 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 72080663 Pathogen - hypothetical protein MHP7448_0326 2 None None None 72080757 Common - putative ICEF Integrative Conjugal Element - IIC MHP7448_0424 3 None None None 72080344 Common dnaN DNA polymerase III beta subunit MHP7448_0002 58 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 72080925 Pathogen - hypothetical protein MHP7448_0597 1 None None None 72080938 Common - hypothetical protein MHP7448_0610 59 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 72080442 Pathogen - hypothetical protein MHP7448_0100 1 None None None 72080409 Common dnaK molecular chaperone DnaK MHP7448_0067 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 72080816 Common - hypothetical protein MHP7448_0485 89 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 72080419 Common rpsL 30S ribosomal protein S12 MHP7448_0077 238 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 72080519 Common rpsH 30S ribosomal protein S8 MHP7448_0180 244 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 72080417 Common fusA elongation factor G MHP7448_0075 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 72080554 Common oppF-1 oligopeptide ABC transporter ATP-binding protein MHP7448_0215 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 72080869 Common - hypothetical protein MHP7448_0538 8 None None None 72080981 Common prsA ribose-phosphate pyrophosphokinase MHP7448_0654 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 72080787 Common acpD-1 acyl carrier protein phosphodiesterase MHP7448_0455 17 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 72080931 Common ppa inorganic pyrophosphatase MHP7448_0603 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 72080515 Common rplO 50S ribosomal protein L15 MHP7448_0176 66 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 72080964 Common nusG transcription antitermination protein NusG MHP7448_0637 215 COG0250 NusG, Transcription antiterminator Transcription 72080653 Common - ABC transporter ATP-binding protein MHP7448_0315 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 72080692 Pathogen - hypothetical protein MHP7448_0356 1 None None None 72080646 Common - hypothetical protein MHP7448_0308 24 COG1511 COG1511, Predicted membrane protein Function unknown 72080489 Pathogen - hypothetical protein MHP7448_0150 1 None None None 72080358 Pathogen - hypothetical protein MHP7448_0016 1 None None None 72080915 Common pulA pullulanase MHP7448_0587 126 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 72080601 Common hpt hypoxanthine-guanine phosphoribosyltransferase MHP7448_0262 150 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 72080862 Common pgiB glucose-6-phosphate isomerase MHP7448_0531 206 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 72080950 Common dam DNA adenine methylase MHP7448_0622 105 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 72080699 Pathogen - hypothetical protein MHP7448_0363 1 None None None 72080959 Common scpA segregation and condensation protein A MHP7448_0632 138 COG1354 COG1354, Uncharacterized conserved protein Function unknown 72080403 Common - hypothetical protein MHP7448_0061 23 COG0327 COG0327, Uncharacterized conserved protein Function unknown 72080514 Common secY preprotein translocase subunit SecY MHP7448_0175 216 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 72080684 Pathogen - hypothetical protein MHP7448_0348 1 COG1158 Rho, Transcription termination factor Transcription 72080410 Common dnaJ heat shock protein DnaJ MHP7448_0068 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 72080599 Common - DNA polymerase III subunit delta' MHP7448_0260 63 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 72080536 Pathogen - hypothetical protein MHP7448_0197 1 None None None 72080587 Pathogen - hypothetical protein MHP7448_0248 1 COG0477 ProP, Permeases of the major facilitator superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / Inorganic ion transport and metabolism / General function prediction only 72080596 Common - hypothetical protein MHP7448_0257 6 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 72080472 Common rpmA 50S ribosomal protein L27 MHP7448_0132 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 72080580 Common secD bifunctional preprotein translocase subunit SecD/SecF MHP7448_0241 207 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 72080377 Common gap glyceraldehyde 3-phosphate dehydrogenase MHP7448_0035 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 72080846 Common xylH xylose ABC transporter permease protein MHP7448_0515 129 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 72080560 Common nrdE ribonucleotide-diphosphate reductase subunit alpha MHP7448_0221 220 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 72080782 Common - hypothetical protein MHP7448_0450 81 COG1692 COG1692, Uncharacterized protein conserved in bacteria Function unknown 72080827 Pathogen - putative p216 surface protein MHP7448_0496 1 None None None 72080977 Common rpsI 30S ribosomal protein S9 MHP7448_0650 248 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 72080627 Pathogen - hypothetical protein MHP7448_0288 1 None None None 72080374 Common ileS isoleucyl-tRNA synthetase MHP7448_0032 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 72080901 Common fba-1 fructose-bisphosphate aldolase MHP7448_0573 176 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 72080963 Common - ISMHp1 transposase MHP7448_0636 30 COG5421 COG5421, Transposase DNA replication, recombination, and repair 72080719 Common - ABC transporter ATP-binding protein MHP7448_0383 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 72080444 Common tpiA triosephosphate isomerase MHP7448_0102 215 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 72080755 Pathogen - hypothetical protein MHP7448_0422 1 None None None 72080455 Common pdhA pyruvate dehydrogenase E1-alpha subunit MHP7448_0115 154 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 72080365 Common - ABC transporter ATP-binding protein MHP7448_0023 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 72080583 Common - hypothetical protein MHP7448_0244 27 COG2731 EbgC, Beta-galactosidase, beta subunit Carbohydrate transport and metabolism 72080997 Common - hypothetical protein MHP7448_0670 6 None None None 72080854 Common tuf elongation factor Tu MHP7448_0523 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 72080490 Common rpe ribulose-phosphate 3-epimerase MHP7448_0151 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 72080937 Common ptsH phosphocarrier protein HPr MHP7448_0609 117 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 72080396 Common recU Holliday junction-specific endonuclease MHP7448_0054 17 COG3331 PrfA, Penicillin-binding protein-related factor A, putative recombinase General function prediction only 72080672 Common - hypothetical protein MHP7448_0335 105 COG1704 LemA, Uncharacterized conserved protein Function unknown 72080800 Pathogen - hypothetical protein MHP7448_0468 2 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 72080361 Common - ABC transporter ATP-binding protein MHP7448_0019 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 72080887 Pathogen - hypothetical protein MHP7448_0556 1 None None None 72080805 Common nadE NH(3)-dependent NAD+ synthetase MHP7448_0473 217 COG0171 NadE, NAD synthase Coenzyme metabolism 72080701 Common - hypothetical protein MHP7448_0365 3 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 72081000 Common - ISMHp1 transposase MHP7448_0673 31 COG5421 COG5421, Transposase DNA replication, recombination, and repair 72080667 Pathogen - hypothetical protein MHP7448_0330 1 None None None 72080425 Common deoA thymidine phosphorylase MHP7448_0083 120 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 72080565 Common iolC myo-inositol catabolism protein MHP7448_0226 146 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 72080574 Common - myo-inositol 2-dehydrogenase MHP7448_0235 183 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 72080830 Pathogen - hypothetical protein MHP7448_0499 2 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 72080743 Pathogen - hypothetical protein MHP7448_0409 1 None None None 72080502 Common tlyA haemolysin MHP7448_0163 131 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 72080498 Pathogen - hypothetical protein MHP7448_0159 1 None None None 72080865 Common frr ribosome recycling factor MHP7448_0534 215 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 72080528 Common rplV 50S ribosomal protein L22 MHP7448_0189 216 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 72080946 Common rplL 50S ribosomal protein L7/L12 MHP7448_0618 210 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 72080968 Common cysS cysteinyl-tRNA synthetase MHP7448_0641 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 72080660 Common - transposase MHP7448_0323 31 COG5421 COG5421, Transposase DNA replication, recombination, and repair 72080710 Common sgaA PTS system, IIA component MHP7448_0374 42 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 72080878 Common - hypothetical protein MHP7448_0547 8 None None None 72080690 Common hit HIT-like protein MHP7448_0354 149 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 72080548 Common trmE tRNA modification GTPase TrmE MHP7448_0209 226 COG0486 ThdF, Predicted GTPase General function prediction only 72080415 Common lepA GTP-binding protein LepA MHP7448_0073 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 72080431 Pathogen - hypothetical protein MHP7448_0089 1 None None None 72080697 Common - ABC transporter ATP-binding protein MHP7448_0361 249 COG3638 COG3638, ABC-type phosphate/phosphonate transport system, ATPase component Inorganic ion transport and metabolism 72080346 Common - hypothetical protein MHP7448_0004 95 COG1576 COG1576, Uncharacterized conserved protein Function unknown 72080526 Common rplP 50S ribosomal protein L16 MHP7448_0187 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 72080366 Common - ABC transporter ATP-binding protein MHP7448_0024 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 72080978 Common rplM 50S ribosomal protein L13 MHP7448_0651 222 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 72080791 Common rplA 50S ribosomal protein L1 MHP7448_0459 246 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 72080517 Common rplR 50S ribosomal protein L18 MHP7448_0178 199 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 72080470 Common ung uracil-DNA glycosylase MHP7448_0130 128 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 72080652 Common - ABC transporter ATP-binding protein MHP7448_0314 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 72080626 Pathogen - hypothetical protein MHP7448_0287 1 None None None 72080375 Common parC DNA topoisomerase IV subunit A MHP7448_0033 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 72080662 Pathogen - hypothetical protein MHP7448_0325 1 None None None 72080728 Common - nicotinate phosphoribosyltransferase MHP7448_0394 96 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 72080648 Common lplA-1 lipoate-protein ligase A MHP7448_0310 72 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 72080725 Common - hypothetical protein MHP7448_0391 110 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 72080843 Pathogen - hypothetical protein MHP7448_0512 1 None None None 72080644 Common - ABC transporter ATP-binding protein MHP7448_0306 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 72080818 Common mgtE putative MG2+ transport protein MHP7448_0487 175 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 72080927 Pathogen - hypothetical protein MHP7448_0599 1 COG2966 COG2966, Uncharacterized conserved protein Function unknown 72080538 Pathogen - protein P102 MHP7448_0199 1 None None None 72080401 Common dnaG DNA primase MHP7448_0059 216 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 72080686 Pathogen - hypothetical protein MHP7448_0350 3 COG3611 DnaB, Replication initiation/membrane attachment protein DNA replication, recombination, and repair 161611229 Common rpsC 30S ribosomal protein S3 MHP7448_0188 245 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 72080612 Common pheS phenylalanyl-tRNA synthetase alpha chain MHP7448_0273 248 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 72080594 Pathogen - hypothetical protein MHP7448_0255 1 None None None 72080749 Common trsE TRSE-like protein MHP7448_0416 18 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 72080466 Common pyk pyruvate kinase MHP7448_0126 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 72080617 Common - hypothetical protein MHP7448_0278 76 COG0196 RibF, FAD synthase Coenzyme metabolism 72080638 Common - hypothetical protein MHP7448_0300 3 None None None 72080971 Common dnaB replicative DNA helicase MHP7448_0644 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 72080716 Common - ABC transporter permease protein MHP7448_0380 35 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 72080759 Common - hypothetical protein MHP7448_0426 2 None None None 72080917 Common thrS threonyl-tRNA synthetase MHP7448_0589 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 72080487 Common - hypothetical protein MHP7448_0148 94 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 72080608 Common smpB SsrA-binding protein MHP7448_0269 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 72080864 Common - phosphatidate cytidylyltransferase synthase MHP7448_0533 20 COG4589 COG4589, Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase General function prediction only