Dechloromonas aromatica RCB, complete genome NC_007298 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 71908393 Common - benzoate 1,2-dioxygenase ferredoxin reductase subunit Daro_2780 184 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 71909176 Common - Phosphate transport system permease protein 2 Daro_3564 220 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 71906614 Common - bifunctional enoyl-CoA hydratase/phosphate acetyltransferase Daro_0975 149 COG0280 Pta, Phosphotransacetylase Energy production and conversion 71909776 Common - Cytochrome c biogenesis protein, transmembrane region Daro_4167 133 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 71909178 Common - PhoU Daro_3566 198 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 71909647 Common - hypothetical protein Daro_4038 110 COG0397 COG0397, Uncharacterized conserved protein Function unknown 71906986 Common - Hydratase/decarboxylase Daro_1354 67 COG3971 COG3971, 2-keto-4-pentenoate hydratase Secondary metabolites biosynthesis, transport, and catabolism 71908042 Nonpathogen - hypothetical protein Daro_2423 5 None None None 71909767 Common - Fe2-S2-type ferredoxin Daro_4158 91 COG3411 COG3411, Ferredoxin Energy production and conversion 71909690 Common - Protein of unknown function DUF6, transmembrane Daro_4081 95 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 71908839 Common - hypothetical protein Daro_3226 7 None None None 71907685 Common - Heat shock protein DnaJ, N-terminal Daro_2058 230 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 71908241 Common - Outer membrane efflux protein Daro_2628 42 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 71907402 Common - PAS Daro_1772 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71906566 Common - hypothetical protein Daro_0927 36 None None None 71907348 Common - Peptidase S14, ClpP Daro_1718 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 71906582 Common - Ribosomal RNA methyltransferase RrmJ/FtsJ Daro_0943 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 71906918 Common - hypothetical protein Daro_1283 63 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 71905953 Common rplL 50S ribosomal protein L7/L12 Daro_0311 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 71906727 Nonpathogen - hypothetical protein Daro_1088 13 None None None 71909409 Common - Phenol hydroxylase subunit Daro_3797 8 None None None 71908938 Nonpathogen - hypothetical protein Daro_3326 14 None None None 71908844 Common - Dienelactone hydrolase Daro_3231 116 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 71908475 Common sdhB succinate dehydrogenase iron-sulfur subunit Daro_2862 193 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 71908122 Nonpathogen - hypothetical protein Daro_2506 1 None None None 71907490 Nonpathogen - hypothetical protein Daro_1861 13 None None None 71907979 Common - ABC transporter related Daro_2360 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 71906894 Common - Nucleotidyl transferase Daro_1256 166 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 71908421 Nonpathogen - hypothetical protein Daro_2808 1 None None None 71909671 Common ruvA Holliday junction DNA helicase motor protein Daro_4062 209 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 71905793 Common - Phosphoglycerate/bisphosphoglycerate mutase Daro_0151 115 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 71907256 Common - hypothetical protein Daro_1625 3 None None None 71907507 Common - Response regulator receiver:Transcriptional regulatory protein, C-terminal Daro_1878 216 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 71907676 Common - PAS:GGDEF Daro_2048 200 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 71908527 Common - phosphoadenosine phosphosulfate reductase Daro_2914 158 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 71906763 Nonpathogen - Protein of unknown function DUF465 Daro_1124 1 COG5481 COG5481, Uncharacterized conserved small protein containing a coiled-coil domain Function unknown 71909096 Common apaG ApaG Daro_3484 89 COG2967 ApaG, Uncharacterized protein affecting Mg2+/Co2+ transport Inorganic ion transport and metabolism 71909147 Common - Glycyl-tRNA synthetase, beta subunit Daro_3535 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 71908298 Common - Protein of unknown function DUF159 Daro_2685 109 COG2135 COG2135, Uncharacterized conserved protein Function unknown 71909688 Common - cytochrome c family protein Daro_4079 22 None None None 71909726 Common - Ubiquinone/menaquinone biosynthesis methyltransferase Daro_4117 198 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 71907380 Common - surface antigen (D15):Surface antigen variable number Daro_1750 159 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 71909181 Common - hypothetical protein Daro_3569 5 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 71906904 Common - colanic acid biosynthesis glycosyl-transferase Daro_1269 85 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 71908507 Common - hypothetical protein Daro_2894 9 None None None 71908328 Common - tRNA 2-selenouridine synthase Daro_2715 65 COG2603 COG2603, Predicted ATPase General function prediction only 71909615 Common - arginine/ornithine transport system ATPase Daro_4005 99 COG1703 ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family Amino acid transport and metabolism 71907029 Common - Serine O-acetyltransferase Daro_1397 203 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 71908039 Common - hypothetical protein Daro_2420 6 None None None 71908457 Common - Peptide chain release factor 2 Daro_2844 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 71908768 Common - hypothetical protein Daro_3155 18 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 71906756 Nonpathogen - hypothetical protein Daro_1117 1 COG4256 HemP, Hemin uptake protein Inorganic ion transport and metabolism 71906634 Common - Beta-lactamase-like Daro_0995 36 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 71907396 Common - Protein of unknown function DUF224, cysteine-rich region Daro_1766 161 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 71908634 Common - Protein of unknown function DUF404, bacteria N-terminal:Protein of unknown function DUF407 Daro_3021 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 71908927 Common glcE glycolate oxidase FAD binding subunit Daro_3314 165 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 71905973 Common rplE 50S ribosomal protein L5 Daro_0331 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 71905984 Common rpsM 30S ribosomal protein S13 Daro_0342 221 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 71907781 Common - Iron-containing alcohol dehydrogenase Daro_2158 166 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 71908078 Common - Peptidase M50 Daro_2460 74 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 71908344 Common - hypothetical protein Daro_2731 25 COG5473 COG5473, Predicted integral membrane protein Function unknown 71907592 Nonpathogen - hypothetical protein Daro_1963 1 None None None 71906321 Common - Helix-turn-helix, Fis-type Daro_0682 173 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 71907962 Common - regulatory protein, LuxR:Response regulator receiver Daro_2343 216 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 71909404 Common - Ferredoxin:Oxidoreductase FAD/NAD(P)-binding:Oxidoreductase FAD-binding region Daro_3792 171 COG2871 NqrF, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF Energy production and conversion 71907970 Common - acyl-CoA synthetase Daro_2351 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 71908321 Common - acetyl-CoA synthetase Daro_2708 220 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 71908691 Common - hypothetical protein Daro_3078 19 None None None 71907332 Common - pyrroloquinoline quinone biosynthesis protein PqqE Daro_1702 152 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 71907531 Common - Histidine kinase, HAMP region:Bacterial chemotaxis sensory transducer Daro_1902 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 71907790 Common - hypothetical protein Daro_2168 3 None None None 71908129 Common - BRO, N-terminal Daro_2513 40 COG3617 COG3617, Prophage antirepressor Transcription 71905917 Common - Septum formation inhibitor MinC Daro_0275 85 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 71905842 Common - ABC transporter related Daro_0200 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 71909638 Nonpathogen - hypothetical protein Daro_4028 3 None None None 71907992 Common - acyl carrier protein Daro_2373 30 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 71909215 Common - hypothetical protein Daro_3603 10 None None None 71907799 Common - hypothetical protein Daro_2177 48 COG3516 COG3516, Uncharacterized protein conserved in bacteria Function unknown 71908456 Common - chemotaxis sensory transducer Daro_2843 137 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 71907387 Common - tRNA/rRNA methyltransferase (SpoU) Daro_1757 209 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 71908463 Common mnmC 5-methylaminomethyl-2-thiouridine methyltransferase Daro_2850 98 COG4121 COG4121, Uncharacterized conserved protein Function unknown 71909017 Common - type II and III secretion system protein Daro_3405 133 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 71906271 Common ntpA dATP pyrophosphohydrolase Daro_0631 38 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 71907535 Common - Patatin Daro_1906 39 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 71906787 Common - chemotaxis-specific methylesterase Daro_1148 168 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 71907499 Common - hypothetical protein Daro_1870 5 None None None 71906172 Common - Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Daro_0532 106 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 71908900 Nonpathogen - hypothetical protein Daro_3287 1 None None None 71907464 Nonpathogen - hypothetical protein Daro_1835 7 COG4314 NosL, Predicted lipoprotein involved in nitrous oxide reduction Energy production and conversion 71906649 Common - Immunoglobulin-like Daro_1010 33 COG5184 ATS1, Alpha-tubulin suppressor and related RCC1 domain-containing proteins Cell division and chromosome partitioning / Cytoskeleton 71905763 Common - hypothetical protein Daro_0121 17 None None None 71905929 Common - lipoyl synthase Daro_0287 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 71906950 Common - Binding-protein-dependent transport systems inner membrane component Daro_1317 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 71906770 Nonpathogen - hypothetical protein Daro_1131 1 None None None 71906957 Common - Phage integrase Daro_1324 91 COG0582 XerC, Integrase DNA replication, recombination, and repair 71906776 Common - Protein of unknown function DUF81 Daro_1137 101 COG0730 COG0730, Predicted permeases General function prediction only 71907966 Common - DNA mismatch repair protein Daro_2347 203 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 71906589 Common - NADH dehydrogenase subunit B Daro_0950 191 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 71908428 Common - Response regulator receiver:Transcriptional regulatory protein, C-terminal Daro_2815 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 71909151 Common - Glyoxalase I Daro_3539 138 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 71906974 Common - Helix-turn-helix, AraC type Daro_1342 62 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 71908018 Common - probable exopolysaccharide biosynthesis protein Daro_2399 126 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 71909332 Common - hypothetical protein Daro_3720 5 None None None 71906073 Common - Phosphoglycerate/bisphosphoglycerate mutase Daro_0433 55 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 71906112 Common - Prokaryotic diacylglycerol kinase Daro_0472 114 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 71908218 Common - Twin-arginine translocation pathway signal Daro_2605 183 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 71908536 Common - Helix-turn-helix, Fis-type Daro_2923 226 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 71909802 Common - Glycosyl transferase, family 2 Daro_4193 126 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 71906703 Nonpathogen - hypothetical protein Daro_1064 2 None None None 71907281 Common - hypothetical protein Daro_1650 7 None None None 71906515 Common - amidophosphoribosyltransferase Daro_0876 239 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 71908381 Common - ABC transporter related Daro_2768 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 71909558 Common - nickel responsive regulator Daro_3947 64 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 71908832 Common - hypothetical protein Daro_3219 12 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 71908003 Common - hypothetical protein Daro_2384 17 COG4309 COG4309, Uncharacterized conserved protein Function unknown 71908258 Common - OmpA/MotB Daro_2645 76 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 71906385 Common - FlgN Daro_0746 12 COG3418 COG3418, Flagellar biosynthesis/type III secretory pathway chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 71909167 Common - Chromate transporter Daro_3555 114 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 71906572 Common - hypothetical protein Daro_0933 76 COG2119 COG2119, Predicted membrane protein Function unknown 71908284 Common ihfA integration host factor subunit alpha Daro_2671 208 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 71906060 Common - PAS Daro_0420 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71908603 Nonpathogen - hypothetical protein Daro_2990 3 None None None 71909225 Common - Conserved hypothetical phage tail region protein Daro_3613 32 None None None 71908036 Common - hypothetical protein Daro_2417 23 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 71906269 Common - acetylglutamate kinase Daro_0629 220 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 71909184 Nonpathogen - hypothetical protein Daro_3572 1 None None None 71905674 Common - Uroporphyrinogen decarboxylase HemE Daro_0032 182 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 71906818 Common - hypothetical protein Daro_1179 9 COG3416 COG3416, Uncharacterized protein conserved in bacteria Function unknown 71908169 Nonpathogen - hypothetical protein Daro_2553 2 None None None 71909553 Common - UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase Daro_3942 207 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 71906187 Common - Protein of unknown function DUF218 Daro_0547 73 COG1434 COG1434, Uncharacterized conserved protein Function unknown 71907244 Common - Polyhydroxyalkanoate synthesis repressor PhaR Daro_1613 67 COG5394 COG5394, Uncharacterized protein conserved in bacteria Function unknown 71908584 Common - hypothetical protein Daro_2971 7 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 71909588 Common - Hydrogenase accessory protein HypB Daro_3978 146 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 71907476 Common - NAD-dependent deacetylase Daro_1847 152 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 71906602 Common - NUDIX hydrolase Daro_0963 167 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 71907134 Common - Protein of unknown function DUF1555 Daro_1502 5 None None None 71906453 Common - Molybdopterin oxidoreductase:Molydopterin dinucleotide-binding region:Molybdopterin oxidoreductase Fe4S4 region:BFD-like (2Fe-2S)-binding region Daro_0814 194 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 71906021 Common - Phenylacetate-CoA oxygenase, PaaI subunit Daro_0379 43 COG3396 COG3396, Uncharacterized conserved protein Function unknown 71906332 Common - OmpA/MotB Daro_0693 69 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 71907740 Common - Enzymatic protein of unknown function Daro_2114 66 COG2170 COG2170, Uncharacterized conserved protein Function unknown 71906883 Common - Acylneuraminate cytidylyltransferase:Aminotransferase class-III Daro_1245 236 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 71909772 Common - Radical SAM Daro_4163 59 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 71906842 Common - GGDEF Daro_1203 185 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 71907804 Common - Rhs element Vgr protein Daro_2182 56 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 71907617 Common - GGDEF Daro_1988 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 71906264 Common - Cytochrome c, class I Daro_0624 60 COG2863 COG2863, Cytochrome c553 Energy production and conversion 71906733 Common - Metal-dependent phosphohydrolase, HD subdomain Daro_1094 60 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 71907564 Common - Short-chain dehydrogenase/reductase SDR Daro_1935 230 COG0623 FabI, Enoyl- acyl-carrier-protein 71907749 Common - RNA polymerase sigma factor Daro_2124 172 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 71908179 Common - Histone-like bacterial DNA-binding protein Daro_2563 200 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 71908720 Common - PAS Daro_3107 223 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 71908237 Common - lipoprotein signal peptidase-like protein Daro_2624 153 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 71907350 Common - Peptidase M20C, Xaa-His dipeptidase Daro_1720 64 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 71906531 Nonpathogen - hypothetical protein Daro_0892 2 None None None 71909473 Common - ThiS, thiamine-biosynthesis Daro_3862 57 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 71909748 Nonpathogen - hypothetical protein Daro_4139 1 None None None 71909476 Common - Sporulation related Daro_3865 31 COG3087 FtsN, Cell division protein Cell division and chromosome partitioning 71908305 Nonpathogen - hypothetical protein Daro_2692 2 None None None 71908343 Common prfC peptide chain release factor 3 Daro_2730 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 71909562 Common - AAA ATPase, central region Daro_3951 181 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 71908589 Common - hypothetical protein Daro_2976 20 COG3242 COG3242, Uncharacterized protein conserved in bacteria Function unknown 71908973 Common - Ornithine cyclodeaminase/mu-crystallin Daro_3361 95 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 71908405 Common - regulatory protein, LysR:LysR, substrate-binding Daro_2792 174 COG0583 LysR, Transcriptional regulator Transcription 71906642 Common - 40-residue YVTN beta-propeller repeat Daro_1003 92 COG3391 COG3391, Uncharacterized conserved protein Function unknown 71908649 Common - putative Tfp pilus assembly protein tip-associated adhesin PilY1 Daro_3036 56 COG3419 PilY1, Tfp pilus assembly protein, tip-associated adhesin PilY1 Cell motility and secretion / Intracellular trafficking and secretion 71909654 Common - inner-membrane translocator Daro_4045 104 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 71909595 Common - Hydrogenase expression/formation protein (HUPF/HYPC) Daro_3985 16 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 71905779 Common - Periplasmic binding protein Daro_0137 131 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 71909426 Common - Ferredoxin:Oxidoreductase FAD/NAD(P)-binding:Oxidoreductase FAD-binding region Daro_3815 146 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 71908675 Common - Protein of unknown function DUF198 Daro_3062 78 COG1469 COG1469, Uncharacterized conserved protein Function unknown 71906985 Common - Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B Daro_1353 30 None None None 71909129 Common - Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Daro_3517 212 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 71909661 Common - OmpA/MotB Daro_4052 145 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 71908303 Nonpathogen - hypothetical protein Daro_2690 1 None None None 71908980 Common - Fumarylacetoacetate (FAA) hydrolase Daro_3368 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 71909415 Common - HpcH/HpaI aldolase Daro_3804 74 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 71906552 Common - ATP-dependent DNA helicase RecQ:ATP-requiring DNA helicase RecQ Daro_0913 221 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 71907755 Nonpathogen - hypothetical protein Daro_2131 1 None None None 71907837 Common - hypothetical protein Daro_2215 6 None None None 71905706 Common - A/G-specific adenine glycosylase MutY Daro_0064 227 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 71908531 Common - hypothetical protein Daro_2918 152 COG1959 COG1959, Predicted transcriptional regulator Transcription 71906991 Common - Oxidoreductase FAD/NAD(P)-binding:Oxidoreductase FAD-binding region Daro_1359 147 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 71909651 Common - ExsB Daro_4042 178 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 71906906 Common - polysaccharide biosynthesis protein Daro_1271 33 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 71906379 Common flhA flagellar biosynthesis protein A Daro_0740 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 71909072 Nonpathogen - hypothetical protein Daro_3460 1 None None None 71907862 Nonpathogen - hypothetical protein Daro_2240 2 COG3972 COG3972, Superfamily I DNA and RNA helicases General function prediction only 71908800 Common - aspartate alpha-decarboxylase Daro_3187 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 71907883 Common - Outer membrane efflux protein Daro_2263 77 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 71906864 Common - hypothetical protein Daro_1225 14 None None None 71908658 Common - Peptidase A8, signal peptidase II Daro_3045 174 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 71909026 Common - Adenylyl cyclase class-3/4/guanylyl cyclase Daro_3414 37 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 71907339 Common - FAD linked oxidase, N-terminal Daro_1709 52 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 71909703 Common - hypothetical protein Daro_4094 11 None None None 71908611 Common rho transcription termination factor Rho Daro_2998 205 COG1158 Rho, Transcription termination factor Transcription 71907224 Common - DNA polymerase III, epsilon subunit:DNA polymerase 3, epsilon subunit Daro_1592 192 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 71907830 Common - TatD-related deoxyribonuclease Daro_2208 217 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 71906716 Common - General substrate transporter:Major facilitator superfamily MFS_1 Daro_1077 167 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 71907033 Nonpathogen - Cytochrome c, class I Daro_1401 2 COG4654 COG4654, Cytochrome c551/c552 Energy production and conversion 71909717 Common - F0F1 ATP synthase subunit A Daro_4108 199 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 71909243 Nonpathogen - hypothetical protein Daro_3631 2 None None None 71909108 Common ddl D-alanine--D-alanine ligase Daro_3496 217 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 71909346 Common - PAS:GGDEF Daro_3734 184 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 71905963 Common rplW 50S ribosomal protein L23 Daro_0321 207 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 71909063 Common - Protein of unknown function zinc binding 2 Daro_3451 87 COG2321 COG2321, Predicted metalloprotease General function prediction only 71908415 Nonpathogen - hypothetical protein Daro_2802 3 None None None 71905935 Common - heat shock protein HtpX Daro_0293 182 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 71906943 Nonpathogen - hypothetical protein Daro_1309 3 None None None 71908775 Common - putative lipoprotein Daro_3162 12 None None None 71907867 Common - Helix-turn-helix motif Daro_2247 27 COG1476 COG1476, Predicted transcriptional regulators Transcription 71908361 Common - Hsp33 protein Daro_2748 127 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 71908130 Nonpathogen - hypothetical protein Daro_2514 1 None None None 71906283 Common - Lytic transglycosylase, catalytic Daro_0643 69 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 71908316 Nonpathogen - hypothetical protein Daro_2703 1 None None None 71907764 Nonpathogen - hypothetical protein Daro_2141 1 None None None 71907908 Nonpathogen - hypothetical protein Daro_2288 2 None None None 71908064 Common - hypothetical protein Daro_2446 12 None None None 71905804 Common - Glycosyl transferase, family 9 Daro_0162 42 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 71908819 Common - 3-deoxy-D-manno-octulosonate cytidylyltransferase Daro_3206 137 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 71906712 Common - Alpha/beta hydrolase fold Daro_1073 64 COG2267 PldB, Lysophospholipase Lipid metabolism 71907595 Nonpathogen - hypothetical protein Daro_1966 1 None None None 71907481 Common - hypothetical protein Daro_1852 10 None None None 71906809 Common - TPR repeat Daro_1170 116 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 71909047 Nonpathogen - hypothetical protein Daro_3435 1 None None None 71908278 Nonpathogen - hypothetical protein Daro_2665 2 None None None 71906501 Common - Entericidin EcnAB Daro_0862 2 None None None 71908148 Nonpathogen - hypothetical protein Daro_2532 1 None None None 71908853 Common - feruloyl-CoA synthase Daro_3240 197 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 71908368 Common - MscS Mechanosensitive ion channel:Conserved TM helix Daro_2755 190 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 71906720 Common - Magnesium and cobalt transport protein CorA Daro_1081 146 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 161377475 Common - acetyl-CoA carboxylase carboxyltransferase subunit alpha Daro_0844 217 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 71909281 Common - coproporphyrinogen III oxidase Daro_3669 113 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 71908985 Common - Sec-independent periplasmic protein translocase Daro_3373 203 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 71908224 Nonpathogen - hypothetical protein Daro_2611 2 None None None 71908913 Common - EAL Daro_3300 51 COG3434 COG3434, Predicted signal transduction protein containing EAL and modified HD-GYP domains Signal transduction mechanisms 71907511 Common - Lipocalin-related protein and Bos/Can/Equ allergen Daro_1882 74 COG3040 Blc, Bacterial lipocalin Cell envelope biogenesis, outer membrane 71906476 Common - Histidine kinase, HAMP region:Bacterial chemotaxis sensory transducer Daro_0837 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 71906601 Common - NADH dehydrogenase subunit N Daro_0962 210 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 71908085 Common - DnaJ central region:Heat shock protein DnaJ, N-terminal:Chaperone DnaJ, C-terminal Daro_2467 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 71905729 Common - Short-chain dehydrogenase/reductase SDR Daro_0087 230 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 71907166 Nonpathogen - hypothetical protein Daro_1534 1 None None None 71906197 Common - Glycosyl hydrolase, BNR repeat Daro_0557 13 COG4692 COG4692, Predicted neuraminidase (sialidase) Carbohydrate transport and metabolism 71907435 Nonpathogen - Transport-associated Daro_1805 1 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 71907847 Nonpathogen - hypothetical protein Daro_2225 3 None None None 71907068 Common - inner-membrane translocator Daro_1436 155 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 71908266 Common - hypothetical protein Daro_2653 43 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 71909489 Nonpathogen - tol protein, membrane spanning protein Daro_3878 1 None None None 71908318 Common - Squalene/phytoene synthase Daro_2705 94 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 71905680 Nonpathogen - hypothetical protein Daro_0038 1 None None None 71909219 Common - tail lysozyme, putative Daro_3607 26 COG3628 COG3628, Phage baseplate assembly protein W General function prediction only 71907195 Nonpathogen - hypothetical protein Daro_1563 6 None None None 71906012 Common - Phenylacetic acid degradation protein paaN2 Daro_0370 159 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 71908486 Common - 2-nitropropane dioxygenase, NPD Daro_2873 97 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 71906528 Common - hypothetical protein Daro_0889 15 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 71909809 Common trmE tRNA modification GTPase TrmE Daro_4200 224 COG0486 ThdF, Predicted GTPase General function prediction only 71905692 Common - Mg chelatase-related protein Daro_0050 188 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 71907590 Common - hypothetical protein Daro_1961 4 None None None 71905791 Common cobS cobalamin synthase Daro_0149 112 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 71908605 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Daro_2992 41 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 71907278 Nonpathogen - hypothetical protein Daro_1647 5 None None None 71909761 Common recA recombinase A Daro_4152 215 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 71908075 Common - Prokaryotic chromosome segregation and condensation protein ScpA Daro_2457 142 COG1354 COG1354, Uncharacterized conserved protein Function unknown 71908960 Nonpathogen - hypothetical protein Daro_3348 16 None None None 71908341 Common - chemotaxis sensory transducer Daro_2728 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 71907947 Common - hypothetical protein Daro_2328 5 None None None 71909784 Common - putative lauroyl/myristoyl acyltransferase involved in LPS biosynthesis Daro_4175 44 COG4261 COG4261, Predicted acyltransferase General function prediction only 71907725 Common - Acetate kinase Daro_2099 162 COG0282 ackA, Acetate kinase Energy production and conversion 71908099 Nonpathogen - hypothetical protein Daro_2481 1 None None None 71909056 Common - LipQ Daro_3444 81 COG0657 Aes, Esterase/lipase Lipid metabolism 71907715 Common - Protein of unknown function DUF125, transmembrane Daro_2089 78 COG1814 COG1814, Uncharacterized membrane protein Function unknown 71908809 Common - iron-sulfur cluster-binding protein Daro_3196 32 COG0348 NapH, Polyferredoxin Energy production and conversion 71907820 Common - Aminodeoxychorismate lyase Daro_2198 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 71905781 Common - Aminotransferase, class I and II Daro_0139 211 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 71906302 Common - N-acetyl-anhydromuranmyl-L-alanine amidase Daro_0663 105 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 71909322 Common - hypothetical protein Daro_3710 8 COG5373 COG5373, Predicted membrane protein Function unknown 71909232 Nonpathogen - hypothetical protein Daro_3620 2 None None None 71908764 Common - hypothetical protein Daro_3151 6 None None None 71906599 Common - NADH-plastoquinone oxidoreductase, chain 5 Daro_0960 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 71909628 Common - malonate decarboxylase subunit beta Daro_4018 206 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 71906478 Common - Major facilitator superfamily MFS_1 Daro_0839 105 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 71906807 Common - Protein of unknown function DUF214 Daro_1168 165 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 71905689 Common - hypothetical protein Daro_0047 11 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 71908797 Common - Protein of unknown function DUF486 Daro_3184 53 COG3169 COG3169, Uncharacterized protein conserved in bacteria Function unknown 71909494 Common - Pilus retraction protein PilT Daro_3883 222 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 71907203 Common - Cytochrome c oxidase, subunit II Daro_1571 43 COG4263 NosZ, Nitrous oxide reductase Energy production and conversion 71908276 Common - TraH Daro_2663 24 None None None 71907242 Common - Acetoacetyl-CoA reductase Daro_1610 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 71908561 Common - thiol-disulfide isomerase and thioredoxins Daro_2948 66 None None None 71907832 Common - hypothetical protein Daro_2210 7 None None None 71905777 Common - Electron transport protein SCO1/SenC Daro_0135 107 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 71907213 Common - Response regulator receiver:Transcriptional regulatory protein, C-terminal Daro_1581 218 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 71907292 Common - Response regulator receiver Daro_1661 209 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 71907827 Nonpathogen - hypothetical protein Daro_2205 2 None None None 71907953 Common - hypothetical protein Daro_2334 30 COG2253 COG2253, Uncharacterized conserved protein Function unknown 71909608 Common - Cytochrome C biogenesis protein Daro_3998 92 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 71906039 Common - Phospholipase D/Transphosphatidylase Daro_0398 2 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 71907627 Common - Small GTP-binding protein domain:GTP-binding protein TypA Daro_1998 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 71906256 Common - RNA methyltransferase TrmH, group 2 Daro_0616 158 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 71906407 Common - Flagellar hook-length control protein Daro_0768 45 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 71908477 Common - succinate dehydrogenase (membrane anchor subunit) Daro_2864 53 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 71905892 Common - ABC transporter related Daro_0250 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 71907819 Common tdk thymidylate kinase Daro_2197 224 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 71906081 Common - dihydrolipoamide acetyltransferase Daro_0441 198 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 71907056 Common - Urease accessory protein UreG Daro_1424 139 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 71906028 Common - Phenylacetic acid degradation operon negative regulatory protein paaX Daro_0386 27 COG3327 PaaX, Phenylacetic acid-responsive transcriptional repressor Transcription 71906802 Common - Electron transport complex, RnfABCDGE type, A subunit Daro_1163 76 COG4657 RnfA, Predicted NADH:ubiquinone oxidoreductase, subunit RnfA Energy production and conversion 71908448 Common - Lipoprotein releasing system, ATP-binding protein Daro_2835 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 71908882 Common - regulatory proteins, AsnC/Lrp Daro_3269 51 COG1522 Lrp, Transcriptional regulators Transcription 71907954 Common - hypothetical protein Daro_2335 25 None None None 71905649 Common - Response regulator receiver:Metal-dependent phosphohydrolase, HD subdomain Daro_0007 225 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 71907858 Common - hypothetical protein Daro_2236 2 None None None 71907901 Common - regulatory protein, ArsR Daro_2281 145 COG0640 ArsR, Predicted transcriptional regulators Transcription 71906017 Common - Thiolase Daro_0375 171 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 71909329 Common - ABC transporter related Daro_3717 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 71905798 Common - Polysaccharide deacetylase Daro_0156 88 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 71908650 Nonpathogen - hypothetical protein Daro_3037 5 COG4726 PilX, Tfp pilus assembly protein PilX Cell motility and secretion / Intracellular trafficking and secretion 71906594 Common - NADH dehydrogenase subunit G Daro_0955 198 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 71907577 Common - hypothetical protein Daro_1948 170 COG1959 COG1959, Predicted transcriptional regulator Transcription 71907280 Nonpathogen - hypothetical protein Daro_1649 1 None None None 71909754 Common - hypothetical protein Daro_4145 5 None None None 71908878 Common - Cyanophycin synthetase Daro_3265 182 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 71909303 Common - Sulphate transport system permease protein 2:Sulfate ABC transporter, permease protein CysW Daro_3691 218 COG4208 CysW, ABC-type sulfate transport system, permease component Inorganic ion transport and metabolism 71906240 Common - TRAP dicarboxylate transporter, DctM subunit Daro_0600 132 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 71908379 Common - Protein of unknown function DUF6, transmembrane Daro_2766 115 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 71909423 Common - regulatory protein, LuxR:Response regulator receiver Daro_3812 216 COG4566 TtrR, Response regulator Signal transduction mechanisms 71907579 Common - Cysteine desulfurase IscS Daro_1950 238 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 71908538 Common - OmpA/MotB Daro_2925 146 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 71907644 Common - acyl-carrier-protein S-malonyltransferase Daro_2016 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 71905766 Common - Protein of unknown function DUF883, ElaB Daro_0124 5 COG4575 ElaB, Uncharacterized conserved protein Function unknown 71908959 Common - TrkA-N Daro_3347 122 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 71907090 Common - Rhodanese-like Daro_1458 56 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 71907009 Nonpathogen - Rickettsia 17 kDa surface antigen Daro_1377 1 COG3134 COG3134, Predicted outer membrane lipoprotein Function unknown 71907261 Nonpathogen - hypothetical protein Daro_1630 1 None None None 71908791 Common - rRNA (guanine-N1-)-methyltransferase, putative Daro_3178 57 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 71905995 Nonpathogen - hypothetical protein Daro_0353 1 None None None 71908222 Nonpathogen - hypothetical protein Daro_2609 2 None None None 71908177 Common - DNA repair exonuclease-like protein Daro_2561 20 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 71908366 Common - Sodium/hydrogen exchanger Daro_2753 78 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 71905879 Common - Glycerophosphoryl diester phosphodiesterase Daro_0237 108 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 71909082 Common rplU 50S ribosomal protein L21 Daro_3470 215 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 71905979 Common rpmD 50S ribosomal protein L30 Daro_0337 155 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 71909514 Common - Small multidrug resistance protein Daro_3903 147 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 71906427 Common - Phage integrase Daro_0788 18 None None None 71909120 Common - PAS:GGDEF Daro_3508 189 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 71907403 Nonpathogen - hypothetical protein Daro_1773 4 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 71907140 Common - Protein of unknown function DUF269 Daro_1508 25 None None None 71907147 Common - Aminotransferase, class V:Aromatic amino acid beta-eliminating lyase/threonine aldolase Daro_1515 239 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 71907649 Common - L-aspartate oxidase Daro_2021 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 71906739 Common - regulatory protein, TetR Daro_1100 84 COG1309 AcrR, Transcriptional regulator Transcription 71907877 Common - ATPase, E1-E2 type:Heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase:Heavy metal translocating P-type ATPase Daro_2257 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 71909239 Common - Phosphoribulokinase/uridine kinase Daro_3627 63 COG3954 PrkB, Phosphoribulokinase Energy production and conversion 71905902 Common - Band 7 protein Daro_0260 210 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 71909504 Common - Protein of unknown function DUF179 Daro_3893 130 COG1678 COG1678, Putative transcriptional regulator Transcription 71909721 Common - ATP synthase F1, alpha subunit Daro_4112 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 71907222 Common - putative aminopeptidase 2 Daro_1590 44 COG1362 LAP4, Aspartyl aminopeptidase Amino acid transport and metabolism 71905987 Common - DNA-directed RNA polymerase subunit alpha Daro_0345 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 71907705 Common - ATPase, E1-E2 type:Magnesium-translocating P-type ATPase Daro_2078 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 71906225 Common - Glucose-1-phosphate adenylyltransferase Daro_0585 180 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 71907948 Common - hypothetical protein Daro_2329 24 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 71906311 Common - D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Daro_0672 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 71907127 Common - Electron transport complex, RnfABCDGE type, D subunit Daro_1495 76 COG4658 RnfD, Predicted NADH:ubiquinone oxidoreductase, subunit RnfD Energy production and conversion 71906890 Nonpathogen - hypothetical protein Daro_1252 1 None None None 71909578 Common - hypothetical protein Daro_3968 25 None None None 71909743 Common - NAD-dependent epimerase/dehydratase:3-beta hydroxysteroid dehydrogenase/isomerase:dTDP-4-dehydrorhamnose reductase:NmrA-like Daro_4134 136 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 71906097 Common - Coenzyme A transferase Daro_0457 108 COG4670 COG4670, Acyl CoA:acetate/3-ketoacid CoA transferase Lipid metabolism 71906875 Common - UDP-glucose 4-epimerase Daro_1236 233 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 71907428 Nonpathogen - hypothetical protein Daro_1798 1 None None None 71908139 Common - Protein-L-isoaspartate(D-aspartate) O-methyltransferase Daro_2523 156 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 71909413 Nonpathogen - hypothetical protein Daro_3802 3 None None None 71906497 Common - chorismate synthase Daro_0858 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 71908869 Common - Nucleoside recognition Daro_3256 39 COG2715 SpmA, Uncharacterized membrane protein, required for spore maturation in B.subtilis. General function prediction only 71906966 Common - hypothetical protein Daro_1334 7 None None None 71905732 Common - enoyl-CoA hydratase Daro_0090 165 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 71906144 Common - hypothetical protein Daro_0504 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 71908471 Common - dihydrolipoamide acetyltransferase Daro_2858 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 71907620 Common - hypothetical protein Daro_1991 26 COG4254 COG4254, Uncharacterized protein conserved in bacteria Function unknown 71909348 Common - YceI Daro_3736 112 COG2353 COG2353, Uncharacterized conserved protein Function unknown 71908892 Common yajC preprotein translocase subunit YajC Daro_3279 118 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 71909256 Common - hypothetical protein Daro_3644 5 None None None 71908945 Common - Large-conductance mechanosensitive channel Daro_3333 144 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 71909534 Common - regulatory protein, TetR Daro_3923 132 COG1309 AcrR, Transcriptional regulator Transcription 71907200 Common - hypothetical protein Daro_1568 9 None None None 71907421 Nonpathogen - hypothetical protein Daro_1791 6 None None None 71907737 Common - Sodium/hydrogen exchanger Daro_2111 20 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 71908023 Common - hypothetical protein Daro_2404 28 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 71909532 Common - thiamine biosynthesis protein ThiC Daro_3921 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 71907085 Common - 4Fe-4S ferredoxin, iron-sulfur binding Daro_1453 96 COG2768 COG2768, Uncharacterized Fe-S center protein General function prediction only 71905719 Common - Glutamine synthetase, catalytic region Daro_0077 221 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 71908292 Common - Phosphoesterase, DHHA1 Daro_2679 11 COG2404 COG2404, Predicted phosphohydrolase (DHH superfamily) General function prediction only 71905743 Common - Phenylacetic acid degradation-related protein Daro_0101 39 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 71906432 Nonpathogen - hypothetical protein Daro_0793 1 None None None 71907782 Common - regulatory protein, TetR Daro_2159 111 COG1309 AcrR, Transcriptional regulator Transcription 71907233 Common - hypothetical protein Daro_1601 8 None None None 71906354 Common - Cbb3-type cytochrome oxidase component Daro_0715 15 COG4736 CcoQ, Cbb3-type cytochrome oxidase, subunit 3 Posttranslational modification, protein turnover, chaperones 71906441 Common - Resolvase, N-terminal Daro_0802 89 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 71906971 Common - Nitroreductase Daro_1339 84 COG0778 NfnB, Nitroreductase Energy production and conversion 71909381 Common - glutamyl-Q tRNA(Asp) synthetase Daro_3769 241 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 71909020 Common - type II secretion system protein Daro_3408 149 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 71908496 Common - chemotaxis sensory transducer Daro_2883 131 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 71908810 Common - von Willebrand factor, type A Daro_3197 45 COG4548 NorD, Nitric oxide reductase activation protein Inorganic ion transport and metabolism 71909117 Common - Cell division protein, FtsL -like Daro_3505 17 COG3116 FtsL, Cell division protein Cell division and chromosome partitioning 71907583 Common hscA chaperone protein HscA Daro_1954 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 71909798 Nonpathogen - hypothetical protein Daro_4189 1 None None None 71907083 Common - Beta-lactamase-like:Flavodoxin/nitric oxide synthase Daro_1451 85 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 71908289 Common - Initiation factor 3 Daro_2676 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 71908566 Common - TonB-dependent receptor Daro_2953 103 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 71908895 Common - Cytochrome B561, bacterial Daro_3282 47 COG3658 COG3658, Cytochrome b Energy production and conversion 71908591 Common - HflK Daro_2978 175 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 71909363 Common - hypothetical protein Daro_3751 12 None None None 71907120 Common - PAS Daro_1488 190 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71908726 Common - L-carnitine dehydratase/bile acid-inducible protein F Daro_3113 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 71907849 Nonpathogen - hypothetical protein Daro_2227 3 None None None 71907182 Common - acetyl-CoA acetyltransferase Daro_1550 182 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 71906467 Common - Cobalamin (vitamin B12) biosynthesis CbiX protein Daro_0828 79 COG2138 COG2138, Uncharacterized conserved protein Function unknown 71906672 Common - hypothetical protein Daro_1033 19 COG1289 COG1289, Predicted membrane protein Function unknown 71908998 Common - Chromate transporter Daro_3386 103 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 71906935 Common - seryl-tRNA synthetase Daro_1300 246 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 71908194 Common - Chlorite dismutase Daro_2580 20 COG3253 COG3253, Uncharacterized conserved protein Function unknown 71909131 Common - Thioesterase superfamily Daro_3519 137 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 71906578 Common carB carbamoyl phosphate synthase large subunit Daro_0939 237 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 71906612 Common - PAS Daro_0973 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71908124 Nonpathogen - hypothetical protein Daro_2508 2 None None None 71909065 Common - Peptidase M23B Daro_3453 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 71905944 Common - dihydroxy-acid dehydratase Daro_0302 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 71906621 Common - Nickel-dependent hydrogenase, large subunit Daro_0982 99 COG3259 FrhA, Coenzyme F420-reducing hydrogenase, alpha subunit Energy production and conversion 71907692 Common - Heat shock protein DnaJ, N-terminal:Chaperone DnaJ, C-terminal Daro_2065 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 71907817 Common - Type IV pilus assembly PilZ Daro_2195 33 COG3215 PilZ, Tfp pilus assembly protein PilZ Cell motility and secretion / Intracellular trafficking and secretion 71908106 Common - hypothetical protein Daro_2489 11 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 71907017 Nonpathogen - hypothetical protein Daro_1385 1 None None None 71909567 Nonpathogen - hypothetical protein Daro_3957 1 None None None 71906701 Common - Bacterioferritin Daro_1062 99 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 71907065 Common - Integrase, catalytic region Daro_1433 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 71909313 Common - Transketolase, central region:Transketolase, C-terminal Daro_3701 190 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 71908594 Common engA GTP-binding protein EngA Daro_2981 236 COG1160 COG1160, Predicted GTPases General function prediction only 71905683 Nonpathogen - hypothetical protein Daro_0041 5 None None None 71906687 Common - coproporphyrinogen III oxidase Daro_1048 204 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 71907637 Common - Peptidase S49 Daro_2009 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 71909158 Common - Cyclic nucleotide-binding Daro_3546 84 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 71908940 Common - Peptidase U62, modulator of DNA gyrase Daro_3328 169 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 71906508 Common - N-(5'phosphoribosyl)anthranilate isomerase (PRAI) Daro_0869 183 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 71909000 Common hisG ATP phosphoribosyltransferase catalytic subunit Daro_3388 214 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 71909787 Nonpathogen - hypothetical protein Daro_4178 4 COG0627 COG0627, Predicted esterase General function prediction only 71907630 Nonpathogen - hypothetical protein Daro_2001 1 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 71907444 Common - Formate dehydrogenase accessory protein Daro_1815 38 COG3058 FdhE, Uncharacterized protein involved in formate dehydrogenase formation Posttranslational modification, protein turnover, chaperones 71907346 Common - Peptidase S16, ATP-dependent protease La Daro_1716 212 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 71909032 Common - Protein of unknown function DUF1239 Daro_3420 29 COG3117 COG3117, Uncharacterized protein conserved in bacteria Function unknown 71906128 Common - Glutathione peroxidase Daro_0488 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 71908646 Common - acetylornithine aminotransferase Daro_3033 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 71908433 Nonpathogen - YeeE/YedE Daro_2820 5 COG2391 COG2391, Predicted transporter component General function prediction only 71907253 Common - PAS Daro_1622 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71908846 Common - Phenylacetic acid degradation-related protein Daro_3233 71 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 71906777 Common - hypothetical protein Daro_1138 42 COG3530 COG3530, Uncharacterized protein conserved in bacteria Function unknown 71906744 Common - hypothetical protein Daro_1105 6 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 71908907 Common - branched-chain amino acid aminotransferase Daro_3294 219 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 71907658 Common era GTP-binding protein Era Daro_2030 233 COG1159 Era, GTPase General function prediction only 71906413 Common - ATP-binding region, ATPase-like:Histidine kinase A, N-terminal Daro_0774 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71906032 Common - Penicillin-binding protein 1C Daro_0390 200 COG4953 PbpC, Membrane carboxypeptidase/penicillin-binding protein PbpC Cell envelope biogenesis, outer membrane 71907999 Common - Nicotinate-nucleotide pyrophosphorylase Daro_2380 203 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 71908834 Common - General secretion pathway protein G Daro_3221 95 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 71906287 Common - putative ubiquinone biosynthesis protein Daro_0647 49 COG2941 CAT5, Ubiquinone biosynthesis protein COQ7 Coenzyme metabolism 71909482 Nonpathogen - hypothetical protein Daro_3871 5 None None None 71908374 Common - Aldo/keto reductase Daro_2761 205 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 71907743 Common - pyruvate kinase Daro_2117 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 71905820 Common - Acyltransferase 3 Daro_0178 23 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 71907929 Nonpathogen - hypothetical protein Daro_2310 3 None None None 71909706 Common - Extracellular ligand-binding receptor Daro_4097 126 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 71907369 Common - PII uridylyl-transferase Daro_1739 124 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 71905788 Common - ATP-binding region, ATPase-like Daro_0146 22 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71909757 Common - Sigma 54 modulation protein/ribosomal protein S30EA Daro_4148 158 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 71908311 Nonpathogen - hypothetical protein Daro_2698 1 None None None 71908750 Common - Twin-arginine translocation pathway signal Daro_3137 88 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 71908681 Common - Ribonuclease BN Daro_3068 84 COG1295 Rbn, Predicted membrane protein Function unknown 71906326 Common - regulatory protein, ArsR Daro_0687 68 COG0640 ArsR, Predicted transcriptional regulators Transcription 71909747 Nonpathogen - hypothetical protein Daro_4138 1 None None None 71905888 Common - Peptidase M48, Ste24p Daro_0246 110 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 71906679 Nonpathogen - hypothetical protein Daro_1040 1 None None None 71906239 Common - Ferritin and Dps Daro_0599 146 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 71908154 Common - hypothetical protein Daro_2538 11 None None None 71907502 Common - hypothetical protein Daro_1873 121 COG1690 RtcB, Uncharacterized conserved protein Function unknown 71906680 Nonpathogen - hypothetical protein Daro_1041 1 None None None 71909466 Common - Protein of unknown function DUF937, bacterial Daro_3855 35 COG3753 COG3753, Uncharacterized protein conserved in bacteria Function unknown 71908512 Common - Biotin biosynthesis protein BioC Daro_2899 134 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 71906231 Nonpathogen - hypothetical protein Daro_0591 1 None None None 71909598 Common - Nickel-dependent hydrogenase, large subunit Daro_3988 102 COG0374 HyaB, Ni,Fe-hydrogenase I large subunit Energy production and conversion 71907880 Common - cytochrome c family protein Daro_2260 21 None None None 71908246 Common - Cd(II)/Pb(II)-responsive transcriptional regulator Daro_2633 132 COG0789 SoxR, Predicted transcriptional regulators Transcription 71907326 Common - cobalt transport protein CbiN Daro_1696 24 COG1930 CbiN, ABC-type cobalt transport system, periplasmic component Inorganic ion transport and metabolism 71905876 Common - Ribonuclease BN Daro_0234 36 COG1295 Rbn, Predicted membrane protein Function unknown 71907839 Common - hypothetical protein Daro_2217 19 None None None 71906397 Common flgK flagellar hook-associated protein FlgK Daro_0758 111 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 71907175 Common - regulatory protein, TetR Daro_1543 103 COG1309 AcrR, Transcriptional regulator Transcription 71908333 Common - GTP-binding protein, HSR1-related Daro_2720 218 COG2262 HflX, GTPases General function prediction only 71909295 Common - Glutaredoxin-related protein Daro_3683 126 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 71906833 Common - hypothetical protein Daro_1194 30 COG3126 COG3126, Uncharacterized protein conserved in bacteria Function unknown 71908772 Common - Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p Daro_3159 207 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 71907842 Common - GGDEF Daro_2220 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 71908666 Nonpathogen - hypothetical protein Daro_3053 1 None None None 71908500 Common - Protein of unknown function DUF132 Daro_2887 17 COG1569 COG1569, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 71905883 Common - periplasmic binding protein-related protein Daro_0241 32 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 71906732 Common - hypothetical protein Daro_1093 13 None None None 71907328 Common - Peptidase S33, proline iminopeptidase 1 Daro_1698 86 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 71906084 Nonpathogen - hypothetical protein Daro_0444 2 None None None 71906121 Common aspA aspartate ammonia-lyase Daro_0481 236 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 71909228 Common - hypothetical protein Daro_3616 9 None None None 71905827 Common - Membrane protein of unknown function Daro_0185 18 COG1950 COG1950, Predicted membrane protein Function unknown 71908395 Common - Helix-turn-helix, AraC type:Arac protein, arabinose-binding/dimerization Daro_2782 32 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 71906092 Common - Sua5/YciO/YrdC/YwlC Daro_0452 234 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 71909692 Common - Phosphoryl transfer system, HPr Daro_4083 104 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 71907537 Nonpathogen - hypothetical protein Daro_1908 1 None None None 71908636 Common - adenosylcobinamide-phosphate synthase Daro_3023 33 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 71909640 Common - TonB-dependent receptor:Lipocalin Daro_4030 125 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 71907461 Common - Sigma-70 region 2 Daro_1832 92 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 71908625 Common - hypothetical protein Daro_3012 6 None None None 71908849 Common - inner-membrane translocator Daro_3236 113 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 71906328 Nonpathogen - hypothetical protein Daro_0689 1 None None None 71906980 Common - Zinc-containing alcohol dehydrogenase superfamily Daro_1348 206 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 71908693 Common - permease YjgP/YjgQ Daro_3080 98 COG0795 COG0795, Predicted permeases General function prediction only 71909583 Common - hydrogenase 2 protein HybA Daro_3973 162 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 71908575 Common - Isochorismatase hydrolase Daro_2962 113 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 71908704 Common - hypothetical protein Daro_3091 36 COG5501 COG5501, Predicted secreted protein Function unknown 71908622 Common - Protein of unknown function DUF403 Daro_3009 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 71907788 Common - hypothetical protein Daro_2166 2 None None None 71906663 Nonpathogen - hypothetical protein Daro_1024 1 None None None 71907687 Common - CsbD-like Daro_2060 32 None None None 71907425 Common - hypothetical protein Daro_1795 3 None None None 71908520 Common - putative signal transduction protein containing EAL and modified HD-GYP domains Daro_2907 42 COG3434 COG3434, Predicted signal transduction protein containing EAL and modified HD-GYP domains Signal transduction mechanisms 71908678 Common - 16S rRNA processing protein RimM Daro_3065 177 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 71907898 Common - Cytochrome c biogenesis protein, transmembrane region Daro_2278 31 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 71907107 Common - Putative molybdenum utilization protein ModD Daro_1475 78 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 71906114 Common - Peptidase M48, Ste24p Daro_0474 88 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 71909435 Common - Transposase, IS4 Daro_3824 46 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 71909018 Common - TPR repeat Daro_3406 28 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 71908694 Common - permease YjgP/YjgQ Daro_3081 72 COG0795 COG0795, Predicted permeases General function prediction only 71906785 Common - MCP methyltransferase, CheR-type Daro_1146 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 71907771 Common - Helix-turn-helix, Fis-type Daro_2148 208 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 71907100 Common - cytochrome C oxidase assembly protein Daro_1468 68 COG3175 COX11, Cytochrome oxidase assembly factor Posttranslational modification, protein turnover, chaperones 71908920 Common - hypothetical protein Daro_3307 8 None None None 71908708 Common - AAA ATPase, central region:Clp, N terminal Daro_3095 241 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 71905926 Nonpathogen - hypothetical protein Daro_0284 1 None None None 71907497 Common - dihydropteridine reductase Daro_1868 61 COG0778 NfnB, Nitroreductase Energy production and conversion 71906387 Common flgA flagellar basal body P-ring biosynthesis protein FlgA Daro_0748 54 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 71906142 Common - hypothetical protein Daro_0502 8 None None None 71909061 Common - N6 adenine-specific DNA methyltransferase, N12 class Daro_3449 47 COG0827 COG0827, Adenine-specific DNA methylase DNA replication, recombination, and repair 71906960 Common - Integration host factor, alpha subunit Daro_1327 209 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 71908462 Nonpathogen - hypothetical protein Daro_2849 3 None None None 71908936 Common - phospho-2-dehydro-3-heoxyheptonate aldolase Daro_3324 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 71906273 Common - Guanine-specific ribonuclease N1 and T1 Daro_0633 25 COG4290 COG4290, Guanyl-specific ribonuclease Sa Nucleotide transport and metabolism 71909731 Common - putative inner membrane protein Daro_4122 59 COG1238 COG1238, Predicted membrane protein Function unknown 71909103 Nonpathogen - hypothetical protein Daro_3491 1 None None None 71905765 Common - AP endonuclease, family 1:Exodeoxyribonuclease III xth Daro_0123 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 71907283 Nonpathogen - hypothetical protein Daro_1652 1 None None None 71907459 Nonpathogen - Twin-arginine translocation pathway signal Daro_1830 7 None None None 71907533 Common - Cupin region Daro_1904 33 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 71906598 Common - NADH dehydrogenase subunit K Daro_0959 158 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 71908282 Common - hypothetical protein Daro_2669 2 None None None 71906064 Common - PAS:GGDEF Daro_0424 191 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 71909811 Common - Protein of unknown function DUF37 Daro_4202 185 COG0759 COG0759, Uncharacterized conserved protein Function unknown 71908423 Nonpathogen - hypothetical protein Daro_2810 1 None None None 71906410 Common - Flagellar assembly protein FliH Daro_0771 29 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 71907776 Common - putative solute-binding periplasmic protein of ABC transport Daro_2153 105 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 71908556 Common - Copper/Zinc superoxide dismutase Daro_2943 87 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 71907697 Common - glucose-6-phosphate 1-dehydrogenase Daro_2070 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 71906622 Common - HoxW protein Daro_0983 11 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 71909804 Common - putative outer membrane protein Daro_4195 9 COG3713 OmpV, Outer membrane protein V Cell envelope biogenesis, outer membrane 71906574 Common - SmpA/OmlA Daro_0935 63 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 71907411 Common - hypothetical protein Daro_1781 16 None None None 71909169 Common - Response regulator receiver:Transcriptional regulatory protein, C-terminal Daro_3557 206 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 71908011 Common - hypothetical protein Daro_2392 20 None None None 71908544 Common - Carboxymuconolactone decarboxylase Daro_2931 90 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 71909022 Nonpathogen - hypothetical protein Daro_3410 3 None None None 71909689 Common - regulatory protein, LysR:LysR, substrate-binding Daro_4080 189 COG0583 LysR, Transcriptional regulator Transcription 71907359 Common - Metal-dependent phosphohydrolase, HD subdomain Daro_1729 130 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 71909796 Common - hypothetical protein Daro_4187 15 COG4706 COG4706, Predicted 3-hydroxylacyl-(acyl carrier protein) dehydratase Lipid metabolism 71907550 Common - Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal:FAD dependent oxidoreductase Daro_1921 149 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 71906106 Common - Competence protein ComEA helix-hairpin-helix region Daro_0466 128 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 71908671 Common - Rieske (2Fe-2S) region Daro_3058 76 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 71909068 Common - hypothetical protein Daro_3456 15 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 71907674 Common - Putative carbohydrate binding:Glycosyltransferase 36:Glycosyltransferase 36 associated Daro_2046 46 COG3459 COG3459, Cellobiose phosphorylase Carbohydrate transport and metabolism 71908745 Common - hypothetical protein Daro_3132 36 COG5501 COG5501, Predicted secreted protein Function unknown 71906401 Common - Flagellar biosynthesis protein FliQ Daro_0762 129 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 71907452 Common - tRNA (uracil-5-)-methyltransferase Daro_1823 160 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 71908903 Common - Metal-dependent phosphohydrolase, HD subdomain Daro_3290 123 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 71905717 Common - amidase Daro_0075 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 71908929 Common - Xylose isomerase-like TIM barrel Daro_3317 81 COG3622 Hfi, Hydroxypyruvate isomerase Carbohydrate transport and metabolism 71908677 Common - tRNA (guanine-N1-)-methyltransferase Daro_3064 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 71908842 Common - Alkaline phosphatase Daro_3229 85 COG1785 PhoA, Alkaline phosphatase Inorganic ion transport and metabolism 71907172 Common - hypothetical protein Daro_1540 2 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 71909140 Common - PhoH-like protein Daro_3528 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 71906983 Nonpathogen - probable regulatory protein, LysR Daro_1351 7 None None None 71906086 Common - 4Fe-4S ferredoxin, iron-sulfur binding:Thiamine pyrophosphate enzyme, C-terminal TPP-binding Daro_0446 106 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 71907394 Common - Iron-sulfur cluster binding protein Daro_1764 95 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 71908025 Common - hypothetical protein Daro_2406 36 None None None 71906305 Common - malic enzyme Daro_0666 212 COG0281 SfcA, Malic enzyme Energy production and conversion 71908799 Common - Pantoate-beta-alanine ligase:Cytidyltransferase-related Daro_3186 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 71907448 Common - Twin-arginine translocation pathway signal Daro_1819 170 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 71907926 Common - hypothetical protein Daro_2307 33 None None None 71906041 Common - regulatory protein, ArsR Daro_0401 46 COG0640 ArsR, Predicted transcriptional regulators Transcription 71906388 Common - Flagellar basal-body rod protein FlgB Daro_0749 94 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 71905664 Common fmt methionyl-tRNA formyltransferase Daro_0022 220 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 71905795 Common - Glycosyl transferase, group 1 Daro_0153 202 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 71908058 Common - UDP-glucose/GDP-mannose dehydrogenase:6-phosphogluconate dehydrogenase, NAD-binding Daro_2440 206 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 71907566 Common - Thioesterase superfamily Daro_1937 75 COG0824 FcbC, Predicted thioesterase General function prediction only 71908685 Common - CDP-diacylglycerol--serine O-phosphatidyltransferase Daro_3072 142 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 71906844 Common - Ppx/GppA phosphatase Daro_1205 181 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 71907355 Common - Pilus retraction protein PilT Daro_1725 211 COG5008 PilU, Tfp pilus assembly protein, ATPase PilU Cell motility and secretion / Intracellular trafficking and secretion 71906896 Common - dTDP-4-dehydrorhamnose epimerase Daro_1258 23 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 71907886 Common - Twin-arginine translocation pathway signal Daro_2266 5 None None None 71907258 Common - Fe-S type hydro-lyase tartrate/fumarate alpha region:Fe-S type hydro-lyase tartrate/fumarate beta region Daro_1627 146 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 71906323 Common - Pentapeptide repeat Daro_0684 107 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 71907661 Common - Holo-acyl carrier protein synthase:Phosphopantethiene-protein transferase Daro_2033 153 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 71907266 Common - Cyclic nucleotide-binding:CBS:Protein of unknown function DUF294, nucleotidyltransferase putative Daro_1635 119 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 71906525 Common - general secretion pathway protein H Daro_0886 12 COG4966 PilW, Tfp pilus assembly protein PilW Cell motility and secretion / Intracellular trafficking and secretion 71907367 Common - hypothetical protein Daro_1737 5 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 71908234 Nonpathogen - hypothetical protein Daro_2621 4 None None None 71905909 Common - indolepyruvate ferredoxin oxidoreductase Daro_0267 93 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 71906371 Common - CheB methylesterase:Response regulator receiver Daro_0732 216 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 71907382 Common - UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase, LpxD Daro_1752 163 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 71908186 Nonpathogen - hypothetical protein Daro_2570 2 None None None 71908264 Common - periplasmic thiol:disulfide interchange protein Daro_2651 63 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 71906584 Common - Dihydropteroate synthase Daro_0945 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 71909277 Common - Dihydrouridine synthase TIM-barrel protein nifR3 Daro_3665 210 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 71909149 Common - Phospholipid/glycerol acyltransferase Daro_3537 109 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 71906857 Common - Ribosomal protein S18 Daro_1218 214 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 71909631 Common - TRAP dicarboxylate transporter, DctM subunit Daro_4021 122 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 71908766 Common - hypothetical protein Daro_3153 62 COG3220 COG3220, Uncharacterized protein conserved in bacteria Function unknown 71906698 Common - probable transmembrane protein Daro_1059 9 None None None 71909424 Common - PAS Daro_3813 224 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 71908529 Nonpathogen - hypothetical protein Daro_2916 6 COG0759 COG0759, Uncharacterized conserved protein Function unknown 71906804 Common - Outer membrane efflux protein Daro_1165 95 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 71908403 Common - Protein of unknown function DUF541 Daro_2790 23 COG3471 COG3471, Predicted periplasmic/secreted protein Function unknown 71909629 Common - Malonate decarboxylase delta subunit Daro_4019 21 None None None 71908256 Nonpathogen - hypothetical protein Daro_2643 3 None None None 71908346 Common - Aldose 1-epimerase Daro_2733 62 COG0676 COG0676, Uncharacterized enzymes related to aldose 1-epimerase Carbohydrate transport and metabolism 71906506 Nonpathogen - hypothetical protein Daro_0867 3 None None None 71907594 Common - Transcription-repair coupling factor Daro_1965 229 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 71908640 Common - Glutamine amidotransferase class-I Daro_3027 109 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 71909719 Common - ATP synthase F0, subunit B Daro_4110 162 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 71905708 Common - Peptidase S16, lon N-terminal Daro_0066 56 COG2802 COG2802, Uncharacterized protein, similar to the N-terminal domain of Lon protease General function prediction only 71905938 Common - Heavy metal efflux pump CzcA Daro_0296 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 71908876 Common - hypothetical protein Daro_3263 14 None None None 71906636 Common - hypothetical protein Daro_0997 8 COG4309 COG4309, Uncharacterized conserved protein Function unknown 71909160 Common - Metallophosphoesterase Daro_3548 69 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 71907078 Common - Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase A, N-terminal Daro_1446 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71907521 Common - Twin-arginine translocation pathway signal Daro_1892 106 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 71908013 Common - Protein of unknown function DUF214 Daro_2394 37 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 71909266 Common - Phage integrase Daro_3654 159 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 71909361 Common - hypothetical protein Daro_3749 9 COG4278 COG4278, Uncharacterized conserved protein Function unknown 71907335 Common - hypothetical protein Daro_1705 54 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 71905964 Common rplB 50S ribosomal protein L2 Daro_0322 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 71908446 Common - hypothetical protein Daro_2833 43 COG3216 COG3216, Uncharacterized protein conserved in bacteria Function unknown 71905822 Common - Ribonuclease E and G Daro_0180 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 71905829 Common - HDIG Daro_0187 124 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 71909597 Common - Nickel-dependent hydrogenase b-type cytochrome subunit Daro_3987 49 COG1969 HyaC, Ni,Fe-hydrogenase I cytochrome b subunit Energy production and conversion 71909724 Common atpC F0F1 ATP synthase subunit epsilon Daro_4115 156 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 71907856 Common - hypothetical protein Daro_2234 10 COG4469 CoiA, Competence protein General function prediction only 71907728 Common - hypothetical protein Daro_2102 18 COG4372 COG4372, Uncharacterized protein conserved in bacteria with the myosin-like domain Function unknown 71907337 Common - hypothetical protein Daro_1707 9 None None None 71906391 Common flgE flagellar hook protein FlgE Daro_0752 128 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 71906448 Common - Ubiquinol-cytochrome c reductase, iron-sulfur subunit Daro_0809 90 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 71906099 Common - Acriflavin resistance protein Daro_0459 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 71908113 Common - Conserved hypothetical protein 698 Daro_2496 97 COG2855 COG2855, Predicted membrane protein Function unknown 71909500 Common - dihydroorotase Daro_3889 207 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 71909682 Common - hypothetical protein Daro_4073 49 COG3832 COG3832, Uncharacterized conserved protein Function unknown 71909604 Common - heme exporter protein D Daro_3994 16 COG3114 CcmD, Heme exporter protein D Intracellular trafficking and secretion 71909041 Nonpathogen - hypothetical protein Daro_3429 1 None None None 71907934 Common - plasmid-like conjugative transfer protein TraE Daro_2315 19 None None None 71908095 Common - hypothetical protein Daro_2477 24 COG5569 COG5569, Uncharacterized conserved protein Function unknown 71906866 Common - 3-demethylubiquinone-9 3-methyltransferase Daro_1227 182 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 71909701 Common - possible signal peptide protein Daro_4092 14 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 71905701 Common - ABC-type phosphate/phosphonate transport system periplasmic component-like protein Daro_0059 23 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 71909344 Common - peptidyl-tRNA hydrolase Daro_3732 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 71906735 Common - Major facilitator superfamily MFS_1 Daro_1096 28 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 71905972 Common rplX 50S ribosomal protein L24 Daro_0330 211 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 71907474 Nonpathogen - hypothetical protein Daro_1845 1 None None None 161377477 Common aroK shikimate kinase Daro_0215 190 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 71909122 Common - hypothetical protein Daro_3510 126 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 71907119 Common - Helix-turn-helix, Fis-type:Nif-specific regulatory protein Daro_1487 172 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 71906653 Common - hypothetical protein Daro_1014 12 None None None 71907312 Common - RNA methyltransferase TrmH, group 1 Daro_1682 156 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 71907597 Common - hypothetical protein Daro_1968 18 None None None 71907762 Common - Cysteine synthase K/M:Cysteine synthase A Daro_2138 218 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 71908066 Common - polynucleotide phosphorylase/polyadenylase Daro_2448 240 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 71906774 Common - Major facilitator superfamily MFS_1 Daro_1135 46 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 71906719 Common - ATP-binding region, ATPase-like:Histidine kinase A, N-terminal:Osmosensitive K+ channel His kinase sensor Daro_1080 219 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 71908582 Common - RNA methyltransferase TrmH, group 3 Daro_2969 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 71908851 Common - 4-hydroxy-2-ketovalerate aldolase Daro_3238 199 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 71908314 Nonpathogen - hypothetical protein Daro_2701 1 None None None 71909350 Common ribH riboflavin synthase subunit beta Daro_3738 230 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 71906826 Common - hypothetical protein Daro_1187 62 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 71909543 Common apaH diadenosine tetraphosphatase Daro_3932 112 None None None 71909528 Common - ABC transporter related Daro_3917 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 71909676 Common - hypothetical protein Daro_4067 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 71909334 Common - Conserved hypothetical protein 95 Daro_3722 211 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 71906398 Common flgL flagellar hook-associated protein FlgL Daro_0759 107 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 71906122 Common - Major facilitator superfamily MFS_1 Daro_0482 211 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 71906545 Common - acetaldehyde dehydrogenase Daro_0906 37 COG4569 MhpF, Acetaldehyde dehydrogenase (acetylating) Secondary metabolites biosynthesis, transport, and catabolism 71906714 Nonpathogen - Membrane protein of unknown function Daro_1075 5 COG1950 COG1950, Predicted membrane protein Function unknown 71909357 Nonpathogen - Protein of unknown function DUF1555 Daro_3745 1 None None None 71905991 Common - Thioesterase superfamily Daro_0349 127 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 71905915 Common - ABC transporter related Daro_0273 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 71908915 Nonpathogen - hypothetical protein Daro_3302 2 None None None 71905954 Common rpoB DNA-directed RNA polymerase subunit beta Daro_0312 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 71906451 Common - Glutathione S-transferase, N-terminal:Glutathione S-transferase, C-terminal Daro_0812 115 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 71908619 Common - PAS Daro_3006 240 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71909300 Common - GGDEF Daro_3688 209 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 71906266 Common - delta-aminolevulinic acid dehydratase Daro_0626 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 71905654 Common - Response regulator receiver Daro_0012 214 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 71909085 Common - gamma-glutamyl kinase Daro_3473 193 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 71906881 Nonpathogen - hypothetical protein Daro_1243 13 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 71907840 Common - hypothetical protein Daro_2218 14 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 71908030 Common - possible CapK protein Daro_2411 120 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 71907823 Common - ErfK/YbiS/YcfS/YnhG Daro_2201 28 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 71909101 Common - Peptidase M23B Daro_3489 189 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 71908161 Nonpathogen - hypothetical protein Daro_2545 6 None None None 71907713 Nonpathogen - osmotically inducible lipoprotein Daro_2087 1 None None None 71906710 Common - CheW-like protein Daro_1071 25 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 71907076 Common - phosphoglucomutase Daro_1444 222 COG0033 Pgm, Phosphoglucomutase Carbohydrate transport and metabolism 71906222 Common - Alpha-glucan phosphorylase Daro_0582 137 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 71909782 Common - AMP-dependent synthetase and ligase Daro_4173 76 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 71906513 Common - Sporulation related Daro_0874 20 COG3147 DedD, Uncharacterized protein conserved in bacteria Function unknown 71909029 Common - Potassium efflux system protein Daro_3417 208 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 71907132 Nonpathogen - hypothetical protein Daro_1500 1 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 71907310 Common - Response regulator receiver Daro_1680 221 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 71908272 Common - hypothetical protein Daro_2659 23 None None None 71906180 Common proA gamma-glutamyl phosphate reductase Daro_0540 188 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 71907890 Nonpathogen - hypothetical protein Daro_2270 1 None None None 71907496 Common - DNA topoisomerase IV subunit B Daro_1867 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 71908363 Common - FAD linked oxidase, C-terminal:FAD linked oxidase, N-terminal Daro_2750 200 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 71907023 Common - NAD(P)H dehydrogenase (quinone):NADPH-dependent FMN reductase Daro_1391 94 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 71907802 Common - Protein of unknown function DUF876, bacterial Daro_2180 49 COG3522 COG3522, Uncharacterized protein conserved in bacteria Function unknown 71908975 Common - succinyl-CoA synthetase subunit alpha Daro_3363 207 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 71909307 Common - PAS:GGDEF Daro_3695 191 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 71907153 Common - Protein of unknown function DUF1109 Daro_1521 20 COG4944 COG4944, Uncharacterized protein conserved in bacteria Function unknown 71905894 Common - inner-membrane translocator Daro_0252 139 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 71906972 Common - Protein of unknown function DUF336 Daro_1340 90 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 71906685 Nonpathogen - hypothetical protein Daro_1046 2 None None None 71907112 Nonpathogen - Helix-turn-helix motif Daro_1480 6 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 71907391 Common - UspA Daro_1761 124 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 71907524 Common - YgfB and YecA Daro_1895 63 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 71906554 Common - Peptidyl-prolyl cis-trans isomerase, cyclophilin type Daro_0915 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 71907545 Common - putative nucleotide-binding protein containing TIR-like domain Daro_1916 20 COG4271 COG4271, Predicted nucleotide-binding protein containing TIR -like domain Transcription 71909613 Common - Acetyl-CoA carboxylase, biotin carboxylase Daro_4003 238 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 71909478 Common - hypothetical protein Daro_3867 40 COG3663 Mug, G:T/U mismatch-specific DNA glycosylase DNA replication, recombination, and repair 71905714 Common - hypothetical protein Daro_0072 42 COG3665 COG3665, Uncharacterized conserved protein Function unknown 71909208 Common - fructose-1,6-bisphosphate aldolase Daro_3596 171 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 71906054 Nonpathogen - hypothetical protein Daro_0414 3 None None None 71908812 Common - VCBS Daro_3199 195 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 71905898 Nonpathogen - hypothetical protein Daro_0256 1 None None None 71907375 Common - Ribosome recycling factor Daro_1745 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 71907330 Common - pyrroloquinoline quinone biosynthesis protein PqqC Daro_1700 37 COG5424 COG5424, Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C Coenzyme metabolism 71909551 Common - 3-dehydroquinate dehydratase Daro_3940 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 71906335 Nonpathogen - hypothetical protein Daro_0696 1 None None None 71906004 Nonpathogen - hypothetical protein Daro_0362 1 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 71906911 Common - Glycosyl transferase, group 1 Daro_1276 170 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 71908828 Common - CBS:Protein of unknown function DUF21:Transporter-associated region Daro_3215 217 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 71908149 Common - hypothetical protein Daro_2533 18 None None None 71908588 Common - ATP phosphoribosyltransferase regulatory subunit Daro_2975 141 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 71907210 Common - Protein of unknown function DUF461 Daro_1578 87 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 71908965 Common - hypothetical protein Daro_3353 36 COG3672 COG3672, Predicted periplasmic protein Function unknown 71908494 Common - periplasmic sugar-binding protein, putative Daro_2881 19 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 71909539 Common - Lipopolysaccharide heptosyltransferase I Daro_3928 60 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 71906927 Common - Smr protein/MutS2 C-terminal Daro_1292 95 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 71907192 Nonpathogen - hypothetical protein Daro_1560 2 None None None 71906892 Common - Glycosyl transferase, group 1 Daro_1254 215 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 71907048 Nonpathogen - hypothetical protein Daro_1416 11 None None None 71909663 Common - TonB, C-terminal Daro_4054 13 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 71907690 Common - putative phosphoketolase Daro_2063 65 COG3957 COG3957, Phosphoketolase Carbohydrate transport and metabolism 71906013 Common - enoyl-CoA hydratase Daro_0371 174 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 71906229 Nonpathogen - hypothetical protein Daro_0589 1 None None None 71907647 Common - 3-oxoacyl-(acyl carrier protein) synthase II Daro_2019 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 71908090 Common - Excinuclease ABC, C subunit, N-terminal Daro_2472 76 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 71906965 Common - Hemerythrin HHE cation binding region Daro_1333 30 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 71907031 Common - PAS Daro_1399 169 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 71907092 Nonpathogen - hypothetical protein Daro_1460 3 None None None 71907205 Common - Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase, dimerization and phosphoacceptor region Daro_1573 218 COG3851 UhpB, Signal transduction histidine kinase, glucose-6-phosphate specific Signal transduction mechanisms 71908307 Common - hypothetical protein Daro_2694 47 COG4643 COG4643, Uncharacterized protein conserved in bacteria Function unknown 71907860 Common - DNA repair exonuclease-like protein Daro_2238 18 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 71908957 Common - Major facilitator superfamily MFS_1 Daro_3345 144 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 71909571 Common - uptake hydrogenase accessory protein hupU Daro_3961 77 COG1740 HyaA, Ni,Fe-hydrogenase I small subunit Energy production and conversion 71909421 Common - 4-oxalocrotonate tautomerase Daro_3810 5 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 71908144 Common - hypothetical protein Daro_2528 5 None None None 71908568 Common - 4Fe-4S ferredoxin, iron-sulfur binding Daro_2955 37 COG0348 NapH, Polyferredoxin Energy production and conversion 71906270 Common - Heat shock protein Hsp20 Daro_0630 159 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 71909371 Common - ATP-binding region, ATPase-like:Histidine kinase A, N-terminal Daro_3759 220 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 71905838 Common - PUA Daro_0196 127 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 71907542 Common - Ketopantoate reductase ApbA/PanE Daro_1913 78 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 71907903 Nonpathogen - hypothetical protein Daro_2283 1 None None None 71907707 Common - Protein of unknown function DUF1328 Daro_2080 4 COG5487 COG5487, Small integral membrane protein Function unknown 71908652 Common - hypothetical protein Daro_3039 18 COG4967 PilV, Tfp pilus assembly protein PilV Cell motility and secretion / Intracellular trafficking and secretion 71907745 Common - General substrate transporter:Major facilitator superfamily MFS_1 Daro_2119 149 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 71909384 Common - TPR repeat Daro_3772 32 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 71905989 Common - PAS Daro_0347 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 71907621 Common - OmpA/MotB Daro_1992 139 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 71906165 Nonpathogen - hypothetical protein Daro_0525 2 None None None 71907936 Common - TraB pilus assembly Daro_2317 25 None None None 71907177 Common - acetyl-CoA acetyltransferase Daro_1545 174 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 71908867 Common - Pseudouridine synthase, Rsu Daro_3254 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 71908299 Nonpathogen - Protein of unknown function DUF1555 Daro_2686 1 None None None 71909288 Common - Peptidase M, neutral zinc metallopeptidase, zinc-binding site Daro_3676 160 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 71907988 Common - hypothetical protein Daro_2369 6 None None None 71906207 Common - Proton-translocating NADH-quinone oxidoreductase, chain M Daro_0567 208 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 71907139 Nonpathogen - Positive regulator of sigma(E), RseC/MucC Daro_1507 1 COG3086 RseC, Positive regulator of sigma E activity Signal transduction mechanisms 71905900 Common - hypothetical protein Daro_0258 9 None None None 71906920 Common - RfaE bifunctional protein, domain I Daro_1285 135 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 71908488 Common - putative SAM-dependent methyltransferase Daro_2875 28 COG3129 COG3129, Predicted SAM-dependent methyltransferase General function prediction only 71909290 Common - hypothetical protein Daro_3678 25 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 71908890 Common - Queuosine biosynthesis protein Daro_3277 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 71906318 Common - Phosphate transporter Daro_0679 166 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 71906056 Nonpathogen - hypothetical protein Daro_0416 1 None None None 71906495 Common - hypothetical protein Daro_0856 7 COG2944 COG2944, Predicted transcriptional regulator Transcription 71908137 Common - RNA polymerase sigma factor RpoS Daro_2521 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 71908136 Common - Lytic murein transglycosylase B Daro_2520 103 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 71907995 Common - Thioredoxin-related Daro_2376 231 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 71909258 Common - Peptidase M3A and M3B, thimet/oligopeptidase F Daro_3646 123 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 71909502 Common - pyrimidine regulatory protein PyrR Daro_3891 111 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 71907263 Common - Response regulator receiver Daro_1632 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 71907509 Common - hypothetical protein Daro_1880 133 COG0432 COG0432, Uncharacterized conserved protein Function unknown 71907875 Nonpathogen - hypothetical protein Daro_2255 1 None None None 71909110 Common murG N-acetylglucosaminyl transferase Daro_3498 207 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 71907642 Common - fatty acid/phospholipid synthesis protein Daro_2014 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 71907739 Common - Sodium/hydrogen exchanger Daro_2113 21 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 71906199 Common - DNA polymerase III, alpha subunit Daro_0559 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 71909411 Common - regulatory protein, LysR:LysR, substrate-binding Daro_3799 192 COG0583 LysR, Transcriptional regulator Transcription 71906421 Common - Flagellar hook-associated protein 2, N-terminal:Flagellar hook-associated 2, C-terminal Daro_0782 109 COG1345 FliD, Flagellar capping protein Cell motility and secretion 71906670 Common - Peptidase S33, proline iminopeptidase 1 Daro_1031 86 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 71907365 Common - UTP--glucose-1-phosphate uridylyltransferase, bacterial and archaeal type Daro_1735 231 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 71908888 Common - Uroporphyrin-III C-methyltransferase, C-terminal Daro_3275 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 71907030 Common - Pyruvate carboxyltransferase Daro_1398 216 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 71908212 Nonpathogen - hypothetical protein Daro_2599 2 None None None 71909641 Common - transport system permease protein Daro_4031 190 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 71907845 Common - Transposase, IS4 Daro_2223 26 COG3385 COG3385, FOG: Transposase and inactivated derivatives DNA replication, recombination, and repair 71906592 Common - NADH dehydrogenase subunit E Daro_0953 156 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 71907405 Nonpathogen - Protein of unknown function DUF1555 Daro_1775 2 None None None 71907433 Common - hypothetical protein Daro_1803 5 None None None 71907945 Common - hypothetical protein Daro_2326 19 None None None 71905980 Common rplO 50S ribosomal protein L15 Daro_0338 216 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 71906220 Common - Glycogen/starch synthase, ADP-glucose type Daro_0580 149 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 71908115 Common - Phage integrase Daro_2498 28 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 71907982 Common - Septum formation initiator Daro_2363 63 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 71908807 Common - ATPase associated with various cellular activities, AAA_5 Daro_3194 76 COG0714 COG0714, MoxR-like ATPases General function prediction only 71909297 Common - periplasmic binding protein-related protein Daro_3685 43 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 71909492 Common - hypothetical protein Daro_3881 26 None None None 71908962 Common - Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal:Hpt Daro_3350 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71908881 Common - NirG protein precursor Daro_3268 49 COG1522 Lrp, Transcriptional regulators Transcription 71906835 Common aat leucyl/phenylalanyl-tRNA--protein transferase Daro_1196 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 71906829 Common - LemA Daro_1190 131 COG1704 LemA, Uncharacterized conserved protein Function unknown 71908383 Common - inner-membrane translocator Daro_2770 148 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 71909602 Common - Cytochrome c-type biogenesis protein CcmB Daro_3992 96 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 71909418 Common - acetaldehyde dehydrogenase Daro_3807 37 COG4569 MhpF, Acetaldehyde dehydrogenase (acetylating) Secondary metabolites biosynthesis, transport, and catabolism 71907689 Common - transaldolase Daro_2062 112 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 71907271 Nonpathogen - hypothetical protein Daro_1640 1 None None None 71907699 Common - Sodium/hydrogen exchanger Daro_2072 29 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 71909261 Common - Cyclic nucleotide-binding:Bacterial regulatory protein, Crp Daro_3649 100 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 71905775 Common - GGDEF Daro_0133 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 71906446 Common - Conserved hypothetical protein 103 Daro_0807 172 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 71907599 Common - AMMECR1 Daro_1970 76 COG2078 AMMECR1, Uncharacterized conserved protein Function unknown 71907825 Nonpathogen - hypothetical protein Daro_2203 1 None None None 71909581 Common - Nickel-dependent hydrogenase, large subunit Daro_3971 105 COG0374 HyaB, Ni,Fe-hydrogenase I large subunit Energy production and conversion 71909674 Common - hypothetical protein Daro_4065 9 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 71906563 Common - GrpE protein Daro_0924 228 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 71908083 Common - glycine dehydrogenase Daro_2465 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 71909136 Common - hypothetical protein Daro_3524 2 None None None 71909093 Common - anthranilate synthase component I Daro_3481 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 71906019 Common - Phenylacetate-CoA oxygenase, PaaG subunit Daro_0377 46 COG3396 COG3396, Uncharacterized conserved protein Function unknown 71908219 Nonpathogen - hypothetical protein Daro_2606 4 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 71909274 Common - Peptidase M24:Peptidase M24B, X-Pro dipeptidase/aminopeptidase N-terminal Daro_3662 212 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 71908722 Common - hypothetical protein Daro_3109 12 None None None 71909054 Common - HylII Daro_3442 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 71909785 Common - hypothetical protein Daro_4176 24 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 71906241 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Daro_0601 72 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 71909214 Common - AAA ATPase, central region Daro_3602 222 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 71909234 Common - hypothetical protein Daro_3622 36 COG4628 COG4628, Uncharacterized conserved protein Function unknown 71908097 Common - Secretion protein HlyD Daro_2479 168 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 71909043 Nonpathogen - hypothetical protein Daro_3431 3 None None None 71906824 Common - Acylphosphatase Daro_1185 128 COG1254 AcyP, Acylphosphatases Energy production and conversion 71907575 Common - Beta-lactamase Daro_1946 148 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 71905800 Common - Glycosyl transferase, group 1 Daro_0158 216 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 71907635 Common - Pseudouridine synthase, RluD Daro_2006 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 71907170 Nonpathogen - hypothetical protein Daro_1538 1 None None None 71907058 Common - UreE urease accessory, N-terminal:UreE urease accessory, C-terminal Daro_1426 62 COG2371 UreE, Urease accessory protein UreE Posttranslational modification, protein turnover, chaperones 71908206 Common - Oxidoreductase, molybdopterin binding Daro_2592 126 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 71905647 Common - D-tyrosyl-tRNA deacylase Daro_0005 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 71908104 Nonpathogen - hypothetical protein Daro_2487 1 None None None 71909430 Nonpathogen - Toluene-4-monooxygenase system B Daro_3819 6 None None None 71906347 Common - Virulence factor MVIN-like Daro_0708 189 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 71908372 Common - Glycosyl transferase, family 2 Daro_2759 161 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 71906538 Common - Monooxygenase, FAD-binding:FAD dependent oxidoreductase Daro_0899 61 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 71908377 Common - chemotaxis sensory transducer Daro_2764 51 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 71906030 Nonpathogen - hypothetical protein Daro_0388 1 None None None 71905986 Common rpsD 30S ribosomal protein S4 Daro_0344 217 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 71908499 Common - Dihydrouridine synthase, DuS Daro_2886 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 71906381 Common - putative MinD-related protein Daro_0742 145 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 71906227 Nonpathogen - hypothetical protein Daro_0587 2 None None None 71907656 Common - possible transmembrane protein Daro_2028 17 None None None 71909459 Common - hypothetical protein Daro_3848 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 71909512 Common - Thiamine monophosphate synthase Daro_3901 157 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 71908762 Nonpathogen - hypothetical protein Daro_3149 1 None None None 71906289 Common rplM 50S ribosomal protein L13 Daro_0649 218 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 71908770 Common - TonB-dependent receptor Daro_3157 117 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 71908151 Common - Prevent-host-death protein Daro_2535 10 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 71909799 Common - putative thioredoxin Daro_4190 31 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 71909248 Common - Heat shock protein DnaJ, N-terminal Daro_3636 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 71906460 Common - Peptidase, metallopeptidase Daro_0821 7 None None None 71906415 Common fliE flagellar hook-basal body protein FliE Daro_0776 86 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 71907255 Nonpathogen - hypothetical protein Daro_1624 4 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 71908509 Common - Alpha/beta hydrolase fold Daro_2896 98 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 71905886 Common - PAS Daro_0244 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71908514 Nonpathogen - Hpt Daro_2901 2 COG2198 ArcB, FOG: HPt domain Signal transduction mechanisms 71906101 Common - Protein of unknown function DUF490 Daro_0461 103 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 71908055 Common - ATP-binding region, ATPase-like:Histidine kinase A, N-terminal Daro_2437 205 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 71908826 Common - hypothetical protein Daro_3213 133 COG2860 COG2860, Predicted membrane protein Function unknown 71908598 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase Daro_2985 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 71907304 Common - regulatory protein, TetR Daro_1674 64 COG1309 AcrR, Transcriptional regulator Transcription 71906058 Common - GCN5-related N-acetyltransferase Daro_0418 50 COG0456 RimI, Acetyltransferases General function prediction only 71905912 Common - Extracellular ligand-binding receptor Daro_0270 141 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 71909759 Common - ABC transporter related Daro_4150 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 71909305 Common - Thiosulphate-binding protein Daro_3693 89 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 71905745 Common - Beta-lactamase-like Daro_0103 89 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 71906877 Common - Glucose-1-phosphate thymidylyltransferase, long form Daro_1238 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 71906159 Common - Methyltransferase small Daro_0519 46 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 71907869 Common - Protein of unknown function DUF6, transmembrane Daro_2249 28 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 71908741 Common - Twin-arginine translocation pathway signal Daro_3128 129 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 71905702 Nonpathogen - Protein of unknown function DUF883, ElaB Daro_0060 2 COG4575 ElaB, Uncharacterized conserved protein Function unknown 71905756 Common - Rod shape-determining protein MreD Daro_0114 52 COG2891 MreD, Cell shape-determining protein Cell envelope biogenesis, outer membrane 71906233 Common thyA thymidylate synthase Daro_0593 141 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 71907924 Nonpathogen - hypothetical protein Daro_2305 3 None None None 71908073 Common - Pseudouridine synthase, Rsu Daro_2455 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 71909138 Common - Phage integrase Daro_3526 38 None None None 71905783 Common - Nitroreductase Daro_0141 114 COG0778 NfnB, Nitroreductase Energy production and conversion 71906373 Common - Response regulator receiver:CheW-like protein Daro_0734 173 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 71905874 Common - Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase A, N-terminal Daro_0232 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71909694 Common - ABC-type phosphate/phosphonate transport system periplasmic component-like protein Daro_4085 15 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 71908923 Common - Helicase, C-terminal:DEAD/DEAH box helicase, N-terminal Daro_3310 238 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 71909119 Common - hypothetical protein Daro_3507 134 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 71905770 Common - Major facilitator superfamily MFS_1 Daro_0128 108 None None None 71908864 Common - regulatory protein, TetR Daro_3251 31 COG1309 AcrR, Transcriptional regulator Transcription 71907812 Common - PAAR Daro_2190 23 COG4104 COG4104, Uncharacterized conserved protein Function unknown 71905881 Common - hypothetical protein Daro_0239 4 None None None 71906761 Common - Protein of unknown function DUF47 Daro_1122 79 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 71907003 Nonpathogen - hypothetical protein Daro_1371 2 None None None 71906526 Nonpathogen - MSHA biogenesis protein MshP Daro_0887 1 COG3156 PulK, Type II secretory pathway, component PulK Intracellular trafficking and secretion 71908909 Common - Lipopolysaccharide heptosyltransferase II Daro_3296 95 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 71907723 Common - Radical SAM Daro_2097 107 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 71908061 Nonpathogen - hypothetical protein Daro_2443 1 None None None 71909704 Common - riboflavin synthase subunit alpha Daro_4095 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 71907680 Common - Transport-associated Daro_2052 44 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 71909241 Common - HAD-superfamily hydrolase subfamily IA, variant 3 Daro_3629 129 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 71908664 Common - 4Fe-4S cluster binding Daro_3051 135 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 71907711 Common - hypothetical protein Daro_2085 8 None None None 71908156 Common - hypothetical protein Daro_2540 6 None None None 71909174 Common - Phosphate binding protein Daro_3562 166 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 71907059 Common ureC urease subunit alpha Daro_1427 96 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 71905741 Common - GCN5-related N-acetyltransferase:Carbonic anhydrase, prokaryotic and plant Daro_0099 129 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 71905720 Common - Creatininase Daro_0078 84 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 71907015 Nonpathogen - hypothetical protein Daro_1383 1 None None None 71906313 Common - PAS Daro_0674 161 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 71908052 Common - AMP-dependent synthetase and ligase Daro_2434 222 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 71909560 Common - hypothetical protein Daro_3949 15 None None None 71905946 Common - Cytochrome c, class I Daro_0304 28 COG4654 COG4654, Cytochrome c551/c552 Energy production and conversion 71908269 Nonpathogen - hypothetical protein Daro_2656 3 None None None 71905805 Common - DNA polymerase A Daro_0163 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 71909198 Common - Conserved hypothetical protein 46 Daro_3586 194 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 71907913 Common - GGDEF Daro_2293 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 71909763 Common - Pseudouridine synthase Daro_4154 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 71909251 Common - hypothetical protein Daro_3639 41 COG4949 COG4949, Uncharacterized membrane-anchored protein conserved in bacteria Function unknown 71908996 Common - hypothetical protein Daro_3384 8 None None None 71908354 Common - hypothetical protein Daro_2741 3 None None None 71908196 Nonpathogen - cytochrome c-554 precursor Daro_2582 11 None None None 71909282 Nonpathogen - hypothetical protein Daro_3670 1 None None None 71907518 Common - Methionine sulfoxide reductase B Daro_1889 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 71907235 Common - putative competence lipoprotein precursor Daro_1603 125 COG4105 ComL, DNA uptake lipoprotein General function prediction only 71907184 Common - putative lipoprotein transmembrane Daro_1552 19 None None None 71906814 Common - conserved hypothetical signal peptide protein Daro_1175 25 COG4731 COG4731, Uncharacterized protein conserved in bacteria Function unknown 71909467 Common - ABC transporter related Daro_3856 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 71905830 Common - S-adenosylmethionine synthetase Daro_0188 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 71908040 Common - Membrane bound O-acyl transferase, MBOAT Daro_2421 86 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 71905685 Common - Cell wall hydrolase/autolysin Daro_0043 22 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 71909074 Common - ABC transporter related Daro_3462 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 71909094 Common - 2-phosphoglycolate phosphatase, prokaryotic:HAD-superfamily hydrolase subfamily IA, variant 3:HAD-superfamily hydrolase, subfamily IA, variant 1 Daro_3482 214 COG0546 Gph, Predicted phosphatases General function prediction only 71909406 Common - Methane/phenol/toluene hydroxylase:YHS Daro_3794 19 None None None 71907344 Nonpathogen - hypothetical protein Daro_1714 1 None None None 71909394 Common - 4-hydroxy-2-ketovalerate aldolase Daro_3782 179 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 71907087 Common - Dinitrogenase iron-molybdenum cofactor biosynthesis Daro_1455 33 COG1433 COG1433, Uncharacterized conserved protein Function unknown 71907441 Common - NAD(P)H dehydrogenase (quinone):NADPH-dependent FMN reductase Daro_1812 11 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 71905851 Common - Penicillin-binding protein 1A Daro_0209 201 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 71905755 Common - Penicillin-binding protein, transpeptidase:Penicillin-binding protein, dimerization domain Daro_0113 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 71907918 Common - Protein of unknown function DUF347 Daro_2299 27 COG4705 COG4705, Uncharacterized membrane-anchored protein conserved in bacteria Function unknown 71906434 Common - KilA, N-terminal Daro_0795 7 None None None 71907010 Nonpathogen - amine oxidase, flavin-containing Daro_1378 1 None None None 71907414 Common - Molybdopterin converting factor, subunit 1 Daro_1784 85 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 71906037 Common - Phospholipase D/Transphosphatidylase Daro_0396 8 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 71907718 Common - hypothetical protein Daro_2092 29 COG3753 COG3753, Uncharacterized protein conserved in bacteria Function unknown 71906062 Nonpathogen - hypothetical protein Daro_0422 12 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 71906258 Common - Biotin synthase Daro_0618 182 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 71908551 Nonpathogen - hypothetical protein Daro_2938 2 None None None 71909337 Common - hypothetical protein Daro_3725 31 COG1160 COG1160, Predicted GTPases General function prediction only 71908351 Common - Sodium:dicarboxylate symporter Daro_2738 163 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 71908970 Common - Beta-lactamase-like Daro_3358 72 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 71907570 Common - hypothetical protein Daro_1941 69 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 71908334 Common - Glu/Leu/Phe/Val dehydrogenase, C terminal:Glu/Leu/Phe/Val dehydrogenase, dimerization region Daro_2721 180 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 71908481 Common - malyl-CoA lyase or citrate lyase, beta subunit Daro_2868 58 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 71909002 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Daro_3390 45 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 71906465 Common - Protein kinase:Protein phosphatase 2C-like Daro_0826 144 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 71906936 Common - Lytic transglycosylase, catalytic Daro_1301 91 COG4623 COG4623, Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein Cell envelope biogenesis, outer membrane 71907797 Common - Protein of unknown function DUF796 Daro_2175 25 COG3157 Hcp, Hemolysin-coregulated protein (uncharacterized) Function unknown 71905690 Common - Rhodanese-like Daro_0048 44 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 71907951 Nonpathogen - hypothetical protein Daro_2332 2 None None None 71909315 Common - Rh-like protein/ammonium transporter Daro_3703 197 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 71909460 Common - Protein kinase Daro_3849 145 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 71909368 Common - pantothenate kinase Daro_3756 90 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 71907807 Common - ImpA, N-terminal Daro_2185 35 COG3515 COG3515, Uncharacterized protein conserved in bacteria Function unknown 71907568 Common - LexA repressor Daro_1939 174 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 71909039 Common - Integron integrase Daro_3427 221 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 71906738 Common - NADH:flavin oxidoreductase/NADH oxidase Daro_1099 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 71909237 Common - Glyceraldehyde-3-phosphate dehydrogenase, type I Daro_3625 230 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 71909323 Common - tryptophan synthase subunit beta Daro_3711 224 COG1350 COG1350, Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB) General function prediction only 71906223 Common - Glycoside hydrolase, family 57 Daro_0583 12 COG1449 COG1449, Alpha-amylase/alpha-mannosidase Carbohydrate transport and metabolism 71907241 Common - Acetoacetyl-CoA reductase Daro_1609 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 71909030 Common - KpsF/GutQ Daro_3418 151 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 71907751 Common - Cytochrome c, class I Daro_2126 55 COG3474 COG3474, Cytochrome c2 Energy production and conversion 71906406 Common - Flagellar basal body-associated protein FliL Daro_0767 22 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 71907415 Common - GTP-binding Daro_1785 103 COG1161 COG1161, Predicted GTPases General function prediction only 71907888 Common - hemerythrin-related protein Daro_2268 3 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 71909338 Common - Formamidopyrimidine-DNA glycolase Daro_3726 181 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 71909124 Common - Histone-like bacterial DNA-binding protein Daro_3512 198 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 71907527 Common - OmpA/MotB Daro_1898 119 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 71907130 Common - pyridine nucleotide transhydrogenase subunit alpha Daro_1498 114 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 71906879 Nonpathogen - hypothetical protein Daro_1241 1 None None None 71907074 Common - cyanate hydratase Daro_1442 41 COG1513 CynS, Cyanate lyase Inorganic ion transport and metabolism 71907833 Common - KAP P-loop Daro_2211 20 COG4928 COG4928, Predicted P-loop ATPase General function prediction only 71906445 Common - AAA ATPase, central region Daro_0806 248 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 71906458 Common - Formate/nitrite transporter Daro_0819 92 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 71905891 Common - AMP-dependent synthetase and ligase Daro_0249 216 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 71905767 Nonpathogen - hypothetical protein Daro_0125 3 COG5393 COG5393, Predicted membrane protein Function unknown 71906757 Common - Helicase, C-terminal:DbpA, RNA-binding:DEAD/DEAH box helicase, N-terminal Daro_1118 232 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 71908616 Nonpathogen - hypothetical protein Daro_3003 7 None None None 71907216 Common - Cytochrome c, class I Daro_1584 56 COG3474 COG3474, Cytochrome c2 Energy production and conversion 71906677 Common - hypothetical protein Daro_1038 2 None None None 71907910 Common - ATP-binding region, ATPase-like Daro_2290 4 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 71906048 Nonpathogen - hypothetical protein Daro_0408 1 None None None 71909538 Common - 3-deoxy-D-manno-octulosonic-acid transferase Daro_3927 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 71906855 Common rpsF 30S ribosomal protein S6 Daro_1216 203 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 71906820 Common - ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal Daro_1181 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71906078 Common - Protein kinase Daro_0438 159 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 71906606 Common - ATP-binding region, ATPase-like:Histidine kinase A, N-terminal Daro_0967 222 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 71907919 Common - conserved hypothetical signal peptide protein Daro_2300 7 None None None 71905691 Common - Drug resistance transporter Bcr/CflA subfamily Daro_0049 222 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 71907101 Nonpathogen - hypothetical protein Daro_1469 1 None None None 71907822 Common - Protein of unknown function DUF833 Daro_2200 48 COG3332 COG3332, Uncharacterized conserved protein Function unknown 71909472 Common thiG thiazole synthase Daro_3861 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 71905651 Common - ApbE-like lipoprotein Daro_0009 136 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 71906195 Common - Response regulator receiver Daro_0555 161 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 71905896 Common - ABC transporter related Daro_0254 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 71907547 Nonpathogen - hypothetical protein Daro_1918 1 None None None 71907603 Common ispF 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Daro_1974 189 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 71909612 Nonpathogen - hypothetical protein Daro_4002 1 None None None 71909301 Common hemA glutamyl-tRNA reductase Daro_3689 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 71908657 Common - Peptidylprolyl isomerase, FKBP-type Daro_3044 113 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 71907016 Common - Ribonuclease H Daro_1384 28 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 71909356 Common - ATP-binding region, ATPase-like:Histidine kinase A, N-terminal Daro_3744 196 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 71907472 Nonpathogen - hypothetical protein Daro_1843 5 None None None 71908165 Common - Peptidase C14, caspase catalytic subunit p20 Daro_2549 17 COG4249 COG4249, Uncharacterized protein containing caspase domain General function prediction only 71905657 Common - hypothetical protein Daro_0015 8 None None None 71906470 Common - Nitrate transport permease Daro_0831 196 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 71908585 Common - 3'-5' exoribonuclease, VacB and RNase II:Ribonuclease R Daro_2972 201 COG0557 VacB, Exoribonuclease R Transcription 71906750 Common - hypothetical protein Daro_1111 20 None None None 71906995 Common - PAS Daro_1363 163 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 71907846 Common - Protein of unknown function DUF159 Daro_2224 69 COG2135 COG2135, Uncharacterized conserved protein Function unknown 71908182 Common - Prophage CP4-57 regulatory Daro_2566 12 COG3311 AlpA, Predicted transcriptional regulator Transcription 71909658 Common - hypothetical protein Daro_4049 18 None None None 71909524 Nonpathogen - hypothetical protein Daro_3913 1 None None None 71907354 Common - succinyl-diaminopimelate desuccinylase Daro_1724 199 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 71909762 Common - hypothetical protein Daro_4153 4 None None None 71909713 Common gidB glucose-inhibited division protein B Daro_4104 205 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 71908442 Common - Protein of unknown function DUF980 Daro_2829 57 COG3228 COG3228, Uncharacterized protein conserved in bacteria Function unknown 71905812 Common - Iojap-related protein Daro_0170 201 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 71908112 Common - regulatory protein, LysR:LysR, substrate-binding Daro_2495 183 COG0583 LysR, Transcriptional regulator Transcription 71906939 Common - Integrase, catalytic region Daro_1305 153 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 71908988 Common - Histidine triad (HIT) protein Daro_3376 235 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 71908497 Common - hypothetical protein Daro_2884 22 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 71909011 Common - VacJ-like lipoprotein Daro_3399 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 71909557 Common - PAS Daro_3946 215 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 71907439 Common - Translation elongation factor, selenocysteine-specific Daro_1810 249 COG3276 SelB, Selenocysteine-specific translation elongation factor Translation, ribosomal structure and biogenesis 71908171 Common - DNA repair protein RadC Daro_2555 174 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 71907116 Nonpathogen - hypothetical protein Daro_1484 3 None None None 71907313 Common - HDIG Daro_1683 44 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 71908814 Common - Type I secretion membrane fusion protein, HlyD Daro_3201 124 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 71909722 Common - F0F1 ATP synthase subunit gamma Daro_4113 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 71906140 Common - Transport-associated Daro_0500 65 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 71907036 Common - cytochrome c family protein Daro_1404 21 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 71908444 Common - Alpha/beta hydrolase fold Daro_2831 140 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 71908642 Common - Protein of unknown function DUF1255 Daro_3029 53 COG3123 COG3123, Uncharacterized protein conserved in bacteria Function unknown 71908247 Common - Sigma-70 region 2 Daro_2634 131 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 71908977 Common - Multi antimicrobial extrusion protein MatE Daro_3365 165 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 71909655 Common - ABC transporter related Daro_4046 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 71908397 Common - Molybdate ABC transporter, ATP-binding protein Daro_2784 249 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 71909378 Common - quinolinate synthetase Daro_3766 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 71909285 Common - Uroporphyrinogen III synthase HEM4 Daro_3673 110 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 71908522 Common - Metal-dependent phosphohydrolase, HD subdomain Daro_2909 56 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 71908761 Nonpathogen - hypothetical protein Daro_3148 1 None None None 71906644 Common - ATP-binding region, ATPase-like:Histidine kinase A, N-terminal Daro_1005 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71905808 Common - Homoserine kinase ThrB Daro_0166 60 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 71906847 Common - Mammalian cell entry related Daro_1208 75 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 71906948 Nonpathogen - hypothetical protein Daro_1314 2 None None None 71908879 Common - Oxidoreductase FAD/NAD(P)-binding:Oxidoreductase FAD-binding region Daro_3266 106 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 71908449 Common - Lipoprotein releasing system, transmembrane protein, LolC/E family Daro_2836 184 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 71908757 Common rpmG 50S ribosomal protein L33 Daro_3144 144 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 71908228 Nonpathogen - hypothetical protein Daro_2615 1 None None None 71908015 Common - hypothetical protein Daro_2396 35 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 71906417 Common - possible flagellar biosynthetic protein Daro_0778 113 COG2257 COG2257, Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB Function unknown 71909105 Common - cell division protein FtsZ Daro_3493 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 71908823 Common - MotA/TolQ/ExbB proton channel Daro_3210 151 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 71909621 Common - Protein of unknown function DUF485 Daro_4011 46 COG3162 COG3162, Predicted membrane protein Function unknown 71909441 Common - Esterase/lipase/thioesterase Daro_3830 82 COG0657 Aes, Esterase/lipase Lipid metabolism 71905863 Nonpathogen - hypothetical protein Daro_0221 1 None None None 71906717 Common - Thioesterase superfamily Daro_1078 29 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 71909605 Common - CcmE/CycJ protein Daro_3995 95 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 71908176 Common - UvrD/REP helicase Daro_2560 212 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 71906860 Common - Transglutaminase-like Daro_1221 26 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 71908229 Nonpathogen - hypothetical protein Daro_2616 9 None None None 71909526 Common - regulatory protein, LysR:LysR, substrate-binding Daro_3915 189 COG0583 LysR, Transcriptional regulator Transcription 71906345 Common - Type I secretion outer membrane protein, TolC Daro_0706 94 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 71908437 Common - polyphosphate kinase Daro_2824 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 71909444 Common - Zinc-containing alcohol dehydrogenase superfamily Daro_3833 173 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 71906867 Common - OmpA/MotB Daro_1228 147 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 71908534 Common - Acetate kinase Daro_2921 166 COG0282 ackA, Acetate kinase Energy production and conversion 71909342 Common - Ribose-phosphate pyrophosphokinase Daro_3730 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 71907768 Common - Alanine dehydrogenase and pyridine nucleotide transhydrogenase Daro_2145 167 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 71906605 Common - type II secretion system protein E:Response regulator receiver:General secretory system II, protein E, N-terminal Daro_0966 239 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 71906695 Common - extracellular solute-binding protein, family 1 Daro_1056 117 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 71906393 Common flgG flagellar basal body rod protein FlgG Daro_0754 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 71907456 Common - Helix-turn-helix, Fis-type Daro_1827 213 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 71909162 Common - Phosphoesterase, PA-phosphatase related Daro_3550 72 None None None 71907774 Common - ABC transporter related Daro_2151 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 71905772 Common metX homoserine O-acetyltransferase Daro_0130 133 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 71905796 Common - Lipid A export ATP-binding/permease protein MsbA Daro_0154 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 71909048 Common - Protein of unknown function DUF1211 Daro_3436 38 COG3548 COG3548, Predicted integral membrane protein Function unknown 71905860 Common - Glutamate synthase, NADH/NADPH, small subunit 1 Daro_0218 184 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 71908482 Common - Pseudouridine synthase Daro_2869 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 71909142 Common - CBS:Transporter-associated region Daro_3530 218 COG4535 CorC, Putative Mg2+ and Co2+ transporter CorC Inorganic ion transport and metabolism 71908479 Common - regulatory protein GntR, HTH:UbiC transcription regulator-associated Daro_2866 132 COG2188 PhnF, Transcriptional regulators Transcription 71908074 Common - Prokaryotic chromosome segregation and condensation protein ScpB Daro_2456 145 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 71907672 Common - hypothetical protein Daro_2044 10 None None None 71906800 Common - electron transport complex protein RnfC Daro_1161 77 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 71908046 Common - Asparagine synthase Daro_2428 139 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 71909193 Common - Major facilitator superfamily MFS_1 Daro_3581 117 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 71909229 Common - Peptidase C14, caspase catalytic subunit p20 Daro_3617 25 None None None 71908731 Nonpathogen - hypothetical protein Daro_3118 1 None None None 71908008 Common - Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase Daro_2389 164 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 71907980 Common - Helix-turn-helix, Fis-type Daro_2361 84 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 71905672 Common - ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal Daro_0030 221 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 71908240 Common - Secretion protein HlyD Daro_2627 171 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 71906178 Common - Methylated-DNA-(protein)-cysteine S-methyltransferase Daro_0538 205 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 71909066 Common - hypothetical protein Daro_3454 6 None None None 71909144 Common - Methionine sulfoxide reductase A Daro_3532 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 71905684 Common - Protein of unknown function DUF861 Daro_0042 29 COG3450 COG3450, Predicted enzyme of the cupin superfamily General function prediction only 71908191 Common - Radical SAM:Molybdenum cofactor synthesis C-terminal Daro_2577 195 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 71908006 Common - aminotransferase AlaT Daro_2387 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 71908424 Common - PAS Daro_2811 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71909495 Common - hypothetical protein Daro_3884 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 71906561 Common - Heat shock protein DnaJ Daro_0922 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 71907114 Nonpathogen - hypothetical protein Daro_1482 1 None None None 71907248 Common - hypothetical protein Daro_1617 50 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 71907494 Nonpathogen - hypothetical protein Daro_1865 1 None None None 71905867 Common - PAS Daro_0225 213 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71907150 Common - Oxidoreductase, molybdopterin binding Daro_1518 126 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 71908213 Common - Helix-turn-helix, Fis-type Daro_2600 193 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 71907384 Common - UDP-N-acetylglucosamine acyltransferase Daro_1754 155 COG1043 LpxA, Acyl- acyl carrier protein 71909733 Common - Protein of unknown function DUF931 Daro_4124 11 COG4392 COG4392, Predicted membrane protein Function unknown 71909486 Common - molybdopterin-guanine dinucleotide biosynthesis protein A Daro_3875 81 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 71907399 Common - hypothetical protein Daro_1769 10 COG4564 COG4564, Signal transduction histidine kinase Signal transduction mechanisms 71905712 Common - hypothetical protein Daro_0070 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 71906403 Common - Flagellar biosynthesis protein, FliO Daro_0764 9 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 71908706 Common - Cold-shock protein, DNA-binding Daro_3093 181 COG1278 CspC, Cold shock proteins Transcription 71909433 Common - RNA-directed DNA polymerase (Reverse transcriptase) Daro_3822 93 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 71906312 Common - Protein of unknown function DUF162 Daro_0673 86 COG1556 COG1556, Uncharacterized conserved protein Function unknown 71908627 Common - ParB-like partition protein Daro_3014 178 COG1475 Spo0J, Predicted transcriptional regulators Transcription 71907785 Common - RND efflux system, outer membrane lipoprotein, NodT Daro_2162 135 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 71908553 Common - hypothetical protein Daro_2940 22 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 71908408 Common - YceI Daro_2795 95 COG2353 COG2353, Uncharacterized conserved protein Function unknown 71907943 Common - hypothetical protein Daro_2324 26 None None None 71908747 Common - Oxidoreductase, molybdopterin binding:Mo-co oxidoreductase dimerization domain Daro_3134 77 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 71908339 Common - hypothetical protein Daro_2726 9 None None None 71906171 Common - hypothetical protein Daro_0531 6 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 71908285 Common - phenylalanyl-tRNA synthetase, beta subunit Daro_2672 246 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 71908937 Common - Radical SAM Daro_3325 106 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 71906585 Common - Phosphoglucosamine mutase Daro_0946 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 71906795 Common - PAS:GGDEF Daro_1156 183 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 71909585 Common - GGDEF Daro_3975 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 71905913 Common - inner-membrane translocator Daro_0271 151 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 71906103 Common - probable site-specific recombinase Daro_0463 23 COG4389 COG4389, Site-specific recombinase DNA replication, recombination, and repair 71908570 Common - Secretion protein HlyD Daro_2957 158 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 71907925 Common - Relaxase Daro_2306 21 None None None 71908293 Common - hypothetical protein Daro_2680 5 None None None 71908412 Common - Metal-dependent phosphohydrolase, HD subdomain Daro_2799 123 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 71907532 Common - Nucleoside 2-deoxyribosyltransferase Daro_1903 19 COG3613 COG3613, Nucleoside 2-deoxyribosyltransferase Nucleotide transport and metabolism 71906162 Common - hypothetical protein Daro_0522 26 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 71908638 Nonpathogen - hypothetical protein Daro_3025 3 None None None 71905924 Common - Putative RNA methylase:THUMP Daro_0282 133 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 71908469 Common - AFG1-like ATPase Daro_2856 103 COG1485 COG1485, Predicted ATPase General function prediction only 71909644 Common - cobyrinic acid a,c-diamide synthase Daro_4034 137 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 71906638 Common - Invasion gene expression up-regulator, SirB Daro_0999 36 COG3094 COG3094, Uncharacterized protein conserved in bacteria Function unknown 71906722 Common - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Daro_1083 133 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 71908489 Common - Phosphatidylserine decarboxylase Daro_2876 97 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 71908696 Common - DNA polymerase III chi subunit, HolC Daro_3083 33 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 71906394 Common - Flagellar L-ring protein Daro_0755 101 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 71908607 Common - C4-dicarboxylate transporter DctA Daro_2994 158 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 71906954 Common gltX glutamyl-tRNA synthetase Daro_1321 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 71907795 Common - Protein of unknown function DUF879, bacterial Daro_2173 48 COG3519 COG3519, Uncharacterized protein conserved in bacteria Function unknown 71908874 Common - Radical SAM Daro_3261 161 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 71909187 Common - Transport-associated Daro_3575 66 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 71909634 Common - regulatory protein GntR, HTH:GntR, C-terminal Daro_4024 136 COG1802 GntR, Transcriptional regulators Transcription 71909457 Common - PAS Daro_3846 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71909737 Common - Cysteine synthase K/M:Cysteine synthase A Daro_4128 221 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 71907619 Common - sensor histidine kinase Daro_1990 20 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 71908119 Common - hypothetical protein Daro_2502 5 None None None 71909684 Common - Protein of unknown function DUF6, transmembrane Daro_4075 150 COG2962 RarD, Predicted permeases General function prediction only 71908702 Common - Peptidase M48, Ste24p Daro_3089 125 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 71909573 Common - Enoyl-CoA hydratase/isomerase:Formyl transferase, N-terminal:Formyl transferase, C-terminal Daro_3963 50 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 71909211 Common - WD-40 repeat Daro_3599 87 COG2319 COG2319, FOG: WD40 repeat General function prediction only 71905662 Common - Peptidoglycan-binding LysM Daro_0020 49 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 71908630 Common - ATP-binding region, ATPase-like:Histidine kinase A, N-terminal Daro_3017 222 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 71908579 Common - GGDEF Daro_2966 175 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 71908711 Common - isocitrate lyase Daro_3098 128 COG2224 AceA, Isocitrate lyase Energy production and conversion 71906293 Common - HesB/YadR/YfhF Daro_0653 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 71908687 Common - Acetolactate synthase, small subunit Daro_3074 191 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 71905998 Common - ATP-dependent DNA helicase RecG Daro_0356 218 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 71908723 Common - Ankyrin Daro_3110 102 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 71906116 Common - regulatory protein, LysR:LysR, substrate-binding Daro_0476 189 COG0583 LysR, Transcriptional regulator Transcription 71906929 Common - Cyclic nucleotide-binding:Bacterial regulatory protein, Crp Daro_1294 173 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 71907681 Common - hypothetical protein Daro_2053 18 None None None 71906067 Common - Protein of unknown function DUF485 Daro_0427 42 COG3162 COG3162, Predicted membrane protein Function unknown 71905668 Common - S-adenosylmethionine decarboxylase related Daro_0026 66 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 71907285 Common - Transposase IS3/IS911 Daro_1654 28 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 71906683 Common - TonB-dependent receptor:TonB box, N-terminal Daro_1044 124 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 71906275 Common - Protein of unknown function DUF502 Daro_0635 84 COG2928 COG2928, Uncharacterized conserved protein Function unknown 71906624 Nonpathogen - hypothetical protein Daro_0985 8 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 71907457 Common - ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal Daro_1828 221 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 71908163 Nonpathogen - hypothetical protein Daro_2547 1 None None None 71908688 Common - Acetolactate synthase, large subunit, biosynthetic type Daro_3075 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 71909250 Common - regulatory protein, LysR:LysR, substrate-binding Daro_3638 191 COG0583 LysR, Transcriptional regulator Transcription 71908715 Common - hypothetical protein Daro_3102 10 None None None 71907664 Common - hypothetical protein Daro_2036 23 COG4394 COG4394, Uncharacterized protein conserved in bacteria Function unknown 71909678 Nonpathogen - hypothetical protein Daro_4069 1 None None None 71908672 Common - Exonuclease VII, small subunit Daro_3059 109 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 71908547 Common - PAS Daro_2934 224 COG3452 COG3452, Predicted periplasmic ligand-binding sensor domain Signal transduction mechanisms 71908432 Nonpathogen - hypothetical protein Daro_2819 1 None None None 71909545 Common - conserved hypothetical protein, predicted autoinducer synthesis protein family Daro_3934 73 COG3176 COG3176, Putative hemolysin General function prediction only 71908934 Common - Cyclic nucleotide-binding Daro_3322 64 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 71907744 Common - MOFRL Daro_2118 86 COG2379 GckA, Putative glycerate kinase Carbohydrate transport and metabolism 71908280 Common - hypothetical protein Daro_2667 3 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 71908836 Common - type II secretion system protein E Daro_3223 217 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 71907290 Common - Histone-like bacterial DNA-binding protein Daro_1659 190 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 71908056 Common - Helix-turn-helix, Fis-type Daro_2438 207 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 71909222 Common - hypothetical protein Daro_3610 18 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 71908788 Common - Tyrosyl-tRNA synthetase, class Ib Daro_3175 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 71906046 Nonpathogen - hypothetical protein Daro_0406 1 None None None 71907606 Nonpathogen - hypothetical protein Daro_1977 3 None None None 71907450 Common - DsrE-like protein Daro_1821 25 COG1553 DsrE, Uncharacterized conserved protein involved in intracellular sulfur reduction Inorganic ion transport and metabolism 71909087 Common - Indole-3-glycerol phosphate synthase Daro_3475 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 71907486 Common - GCN5-related N-acetyltransferase Daro_1857 5 COG0456 RimI, Acetyltransferases General function prediction only 71906810 Common - MltA-interacting MipA Daro_1171 30 COG3713 OmpV, Outer membrane protein V Cell envelope biogenesis, outer membrane 71907299 Common - Cyclic nucleotide-binding Daro_1669 140 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 71907460 Common - hypothetical protein Daro_1831 34 COG2836 COG2836, Uncharacterized conserved protein Function unknown 71909728 Common - hypothetical protein Daro_4119 9 None None None 71906962 Common - Response regulator receiver Daro_1330 214 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 71907786 Common - hypothetical protein Daro_2163 6 None None None 71907487 Common - Patatin Daro_1858 60 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 71905831 Common - lipid A biosynthesis lauroyl acyltransferase Daro_0189 108 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 71908995 Common - histidinol-phosphate aminotransferase Daro_3383 233 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 71908357 Common - RNA binding S1 Daro_2744 164 COG2183 Tex, Transcriptional accessory protein Transcription 71906888 Common - hypothetical protein Daro_1250 5 None None None 71905911 Nonpathogen - hypothetical protein Daro_0269 3 None None None 71909207 Common - pyruvate kinase Daro_3595 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 71909416 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Daro_3805 44 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 71907342 Common - Transposase IS3/IS911 Daro_1712 28 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 71907653 Common - Glutaredoxin 2 Daro_2025 14 None None None 71906705 Common - 4Fe-4S ferredoxin, iron-sulfur binding Daro_1066 99 COG0348 NapH, Polyferredoxin Energy production and conversion 71906251 Common - Rhodanese-like Daro_0611 183 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 71906367 Common - Histidine kinase, HAMP region:Bacterial chemotaxis sensory transducer Daro_0728 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 71907013 Common - DNA polymerase III, epsilon subunit Daro_1381 170 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 71906350 Common - ATPase, E1-E2 type:Copper-translocating P-type ATPase:Heavy metal translocating P-type ATPase Daro_0711 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 71909452 Common - TatD-related deoxyribonuclease Daro_3841 236 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 71907187 Common - Acyl-CoA dehydrogenase, C-terminal:Acyl-CoA dehydrogenase, central region Daro_1555 144 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 71907237 Common - Protein of unknown function DUF152 Daro_1605 180 COG1496 COG1496, Uncharacterized conserved protein Function unknown 71907613 Common - hypothetical protein Daro_1984 33 None None None 71908198 Common - Molybdopterin oxidoreductase:Molydopterin dinucleotide-binding region Daro_2584 165 COG5013 NarG, Nitrate reductase alpha subunit Energy production and conversion 71906336 Common - Cl- channel, voltage gated Daro_0697 89 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 71907916 Common - ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal Daro_2297 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71907352 Common - Spermidine synthase-like protein Daro_1722 43 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 71906361 Common - chemotaxis motA protein Daro_0722 88 COG1291 MotA, Flagellar motor component Cell motility and secretion 71907873 Common - Secretion protein HlyD Daro_2253 162 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 71905723 Common - ABC transport system substrate-binding protein Daro_0081 53 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 71909469 Common rdgC recombination associated protein Daro_3858 53 COG2974 RdgC, DNA recombination-dependent growth factor C DNA replication, recombination, and repair 71906190 Common - putative partition-related protein Daro_0550 78 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 71907793 Common - AAA ATPase, central region:Clp, N terminal Daro_2171 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 71908821 Common - Tetraacyldisaccharide-1-P 4'-kinase Daro_3208 124 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 71906436 Common - BRO, N-terminal Daro_0797 39 COG3617 COG3617, Prophage antirepressor Transcription 71908120 Nonpathogen - hypothetical protein Daro_2503 1 None None None 71905679 Common - ROK Daro_0037 145 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 71908562 Common - permease Daro_2949 105 COG0701 COG0701, Predicted permeases General function prediction only 71907301 Common - ABC transporter related Daro_1671 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 71906675 Common - Cyclic nucleotide-binding Daro_1036 148 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 71906617 Common - enoyl-(acyl carrier protein) reductase Daro_0978 233 COG0623 FabI, Enoyl- acyl-carrier-protein 71905802 Common - Glycosyl transferase, group 1 Daro_0160 218 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 71907373 Common tsf elongation factor Ts Daro_1743 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 71909195 Common - hypothetical protein Daro_3583 72 COG2924 COG2924, Uncharacterized protein conserved in bacteria Function unknown 71907159 Common - regulatory protein, TetR Daro_1527 107 COG1309 AcrR, Transcriptional regulator Transcription 71908102 Common - Peptidase M24A, methionine aminopeptidase, subfamily 1 Daro_2485 246 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 71907052 Common - hypothetical protein Daro_1420 23 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 71908559 Common - Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal Daro_2946 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71906243 Common - Glycine hydroxymethyltransferase:Aminotransferase, class I and II Daro_0603 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 71907045 Common - Nitrogenase molybdenum-iron protein beta chain Daro_1413 53 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 71907670 Nonpathogen - hypothetical protein Daro_2042 1 None None None 71906463 Common - hypothetical protein Daro_0824 9 None None None 71907931 Common - OmpA/MotB Daro_2312 87 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 71905753 Common - Rare lipoprotein A Daro_0111 136 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 71907779 Nonpathogen - hypothetical protein Daro_2156 1 None None None 71906783 Common - CheW-like protein Daro_1144 128 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 71909036 Common - Molybdopterin binding domain Daro_3424 162 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 71909696 Common - Sel1-like repeat Daro_4087 89 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 71907835 Common - hypothetical protein Daro_2213 9 COG4861 COG4861, Uncharacterized protein conserved in bacteria Function unknown 71906748 Common - putative regulatory protein Daro_1109 34 COG0348 NapH, Polyferredoxin Energy production and conversion 71906339 Common - Bile acid:sodium symporter Daro_0700 125 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 71908474 Common - Protein of unknown function DUF339 Daro_2861 30 COG2938 COG2938, Uncharacterized conserved protein Function unknown 71909223 Nonpathogen - hypothetical protein Daro_3611 1 None None None 71907230 Nonpathogen - hypothetical protein Daro_1598 1 None None None 71909246 Common - hypothetical protein Daro_3634 5 None None None 71909154 Common - Response regulator receiver Daro_3542 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 71908595 Common - Pyrrolo-quinoline quinone Daro_2982 115 COG1520 COG1520, FOG: WD40-like repeat Function unknown 71909666 Common - 4-hydroxybenzoyl-CoA thioesterase Daro_4057 134 COG0824 FcbC, Predicted thioesterase General function prediction only 71908370 Common - GtrA-like protein Daro_2757 13 COG2246 COG2246, Predicted membrane protein Function unknown 71909609 Common - TPR repeat Daro_3999 79 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 71906035 Common - hypothetical protein Daro_0393 2 None None None 71906076 Common - hypothetical protein Daro_0436 15 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 71909396 Common - Short-chain dehydrogenase/reductase SDR Daro_3784 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 71909004 Common - Cold-shock protein, DNA-binding Daro_3392 180 COG1278 CspC, Cold shock proteins Transcription 71907000 Nonpathogen - hypothetical protein Daro_1368 1 None None None 71908054 Common - sugar transferase Daro_2436 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 71909268 Common - RRNA 16S rRNA dimethylase Daro_3656 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 71905966 Common rplV 50S ribosomal protein L22 Daro_0324 221 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 71908155 Nonpathogen - hypothetical protein Daro_2539 2 None None None 71905957 Common - 30S ribosomal protein S7 Daro_0315 242 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 71908127 Nonpathogen - hypothetical protein Daro_2511 2 None None None 71908158 Common - ParB-like partition protein Daro_2542 179 COG1475 Spo0J, Predicted transcriptional regulators Transcription 71906656 Common - Helix-turn-helix, Fis-type Daro_1017 179 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 71906536 Common - DNA-binding transcriptional activator, 3HPP-binding Daro_0897 97 COG1414 IclR, Transcriptional regulator Transcription 71906280 Common - CBS:Protein of unknown function DUF21:Transporter-associated region Daro_0640 217 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 71905872 Common - GGDEF Daro_0230 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 71907152 Common - RNA polymerase sigma factor Daro_1520 120 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 71906205 Common - hypothetical protein Daro_0565 40 COG3002 COG3002, Uncharacterized protein conserved in bacteria Function unknown 71907221 Common - hypothetical protein Daro_1589 27 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 71909403 Common - Ferredoxin Daro_3791 8 COG0633 Fdx, Ferredoxin Energy production and conversion 71907893 Nonpathogen - hypothetical protein Daro_2273 1 None None None 71908991 Common - Histidine biosynthesis protein HisF Daro_3379 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 71906157 Common - AAA ATPase, central region:ATPase associated with various cellular activities, AAA_5 Daro_0517 98 COG0714 COG0714, MoxR-like ATPases General function prediction only 71907321 Common - Precorrin-8X methylmutase CbiC/CobH Daro_1691 118 COG2082 CobH, Precorrin isomerase Coenzyme metabolism 71908754 Common - bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase Daro_3141 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 71906998 Common - hypothetical protein Daro_1366 4 None None None 71908902 Common - Glutathione S-transferase, N-terminal:Glutathione S-transferase, C-terminal Daro_3289 111 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 71909636 Common - Protein of unknown function DUF589 Daro_4026 93 COG2947 COG2947, Uncharacterized conserved protein Function unknown 71905849 Common - Diaminopimelate decarboxylase Daro_0207 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 71908862 Nonpathogen - hypothetical protein Daro_3249 1 None None None 71907515 Common - Helix-turn-helix, AraC type:Arac protein, arabinose-binding/dimerization Daro_1886 74 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 71908109 Common - Cytochrome c, class I Daro_2492 75 COG3258 COG3258, Cytochrome c Energy production and conversion 71905931 Common - Protein of unknown function DUF493 Daro_0289 56 COG2921 COG2921, Uncharacterized conserved protein Function unknown 71905875 Common - phosphoglyceromutase Daro_0233 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 71909794 Common - 3-oxoacyl-(acyl carrier protein) synthase I Daro_4185 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 71906898 Common - Glycosyl transferase, family 2 Daro_1260 194 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 71907088 Nonpathogen - hypothetical protein Daro_1456 2 None None None 71908743 Common - hypothetical protein Daro_3130 28 COG3258 COG3258, Cytochrome c Energy production and conversion 71908521 Common - Periplasmic copper-binding Daro_2908 53 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 71905971 Common rplN 50S ribosomal protein L14 Daro_0329 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 71905824 Common - ProQ activator of osmoprotectant transporter ProP Daro_0182 27 COG3109 ProQ, Activator of osmoprotectant transporter ProP Signal transduction mechanisms 71908419 Nonpathogen - hypothetical protein Daro_2806 1 None None None 71908375 Common - Hemerythrin HHE cation binding region Daro_2762 23 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 71908096 Common - Outer membrane efflux protein Daro_2478 82 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 71907121 Common - Electron transport complex, RnfABCDGE type, G subunit Daro_1489 58 COG4659 RnfG, Predicted NADH:ubiquinone oxidoreductase, subunit RnfG Energy production and conversion 71908504 Common - Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase A, N-terminal Daro_2891 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71905758 Common - Cell shape determining protein MreB/Mrl Daro_0116 236 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 71909217 Common - hypothetical protein Daro_3605 11 None None None 71907716 Common - Phospholipase A1 Daro_2090 52 COG2829 PldA, Outer membrane phospholipase A Cell envelope biogenesis, outer membrane 71909436 Common - hypothetical protein Daro_3825 3 None None None 71909623 Common - Protein of unknown function DUF81 Daro_4013 108 COG0730 COG0730, Predicted permeases General function prediction only 71906760 Nonpathogen - hypothetical protein Daro_1121 1 None None None 71909276 Common - 1,4-dihydroxy-2-naphthoate octaprenyltransferase Daro_3664 100 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 71907362 Common - Chromosome segregation protein SMC Daro_1732 184 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 71907357 Common - hypothetical protein Daro_1727 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 71906221 Common - Phosphoglucose isomerase (PGI) Daro_0581 198 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 71906579 Common - Prokaryotic transcription elongation factor GreA Daro_0940 203 COG0782 GreA, Transcription elongation factor Transcription 71906803 Common - Dihydroorotate dehydrogenase 2 Daro_1164 226 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 71906546 Common - 4-hydroxy-2-ketovalerate aldolase Daro_0907 171 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 71905836 Common - Tyrosine recombinase XerC Daro_0194 215 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 71907020 Common - Cold-shock protein, DNA-binding Daro_1388 181 COG1278 CspC, Cold shock proteins Transcription 71907854 Nonpathogen - hypothetical protein Daro_2232 2 None None None 71907708 Common - Phospholipase D/Transphosphatidylase Daro_2081 153 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 71909675 Nonpathogen - hypothetical protein Daro_4066 2 None None None 71906870 Common - phosphoserine aminotransferase Daro_1231 117 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 71906108 Common - UvrD/REP helicase Daro_0468 184 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 71908963 Common - hypothetical protein Daro_3351 2 COG2198 ArcB, FOG: HPt domain Signal transduction mechanisms 71907389 Common - phosphoenolpyruvate carboxylase Daro_1759 116 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 71908209 Nonpathogen - hypothetical protein Daro_2596 2 None None None 71907274 Nonpathogen - hypothetical protein Daro_1643 1 None None None 71906825 Common - phytochelatin synthase-like protein Daro_1186 12 None None None 71909397 Common - Hydratase/decarboxylase Daro_3785 67 COG3971 COG3971, 2-keto-4-pentenoate hydratase Secondary metabolites biosynthesis, transport, and catabolism 71908071 Common nusA transcription elongation factor NusA Daro_2453 217 COG0195 NusA, Transcription elongation factor Transcription 71905785 Nonpathogen - hypothetical protein Daro_0143 4 None None None 71906298 Common - hypothetical protein Daro_0659 6 None None None 71906307 Common - regulatory proteins, IclR Daro_0668 118 COG1414 IclR, Transcriptional regulator Transcription 71908886 Nonpathogen - hypothetical protein Daro_3273 7 None None None 71907573 Common - hypothetical protein Daro_1944 3 None None None 71907268 Common - Na+/solute symporter Daro_1637 167 COG4147 DhlC, Predicted symporter General function prediction only 71907164 Common - Phasin Daro_1532 15 None None None 71905815 Common - phosphopantetheinyl transferase-like protein Daro_0173 4 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 71907191 Common - Metal-dependent phosphohydrolase, HD subdomain Daro_1559 123 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 71908336 Common - Protein of unknown function DUF1684 Daro_2723 26 COG3358 COG3358, Uncharacterized conserved protein Function unknown 71907207 Common - Cytochrome c oxidase, subunit II Daro_1575 43 COG4263 NosZ, Nitrous oxide reductase Energy production and conversion 71909134 Nonpathogen - Protein of unknown function DUF1376 Daro_3522 1 COG3756 COG3756, Uncharacterized protein conserved in bacteria Function unknown 71909076 Nonpathogen - hypothetical protein Daro_3464 1 None None None 71906246 Common - UBA/THIF-type NAD/FAD binding fold:MoeZ/MoeB Daro_0606 223 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 71907747 Nonpathogen - hypothetical protein Daro_2122 1 None None None 71907589 Nonpathogen - hypothetical protein Daro_1960 4 None None None 71905697 Common - Isochorismatase hydrolase Daro_0055 83 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 71906161 Common - Sigma-70 region 2:Sigma-70 region 4 Daro_0521 168 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 71906150 Common - Transglutaminase-like Daro_0510 90 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 71908609 Common - regulatory protein, LuxR:Response regulator receiver Daro_2996 208 COG4566 TtrR, Response regulator Signal transduction mechanisms 71908187 Nonpathogen - hypothetical protein Daro_2571 2 None None None 71905794 Common - Lipopolysaccharide heptosyltransferase III, putative Daro_0152 111 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 71906759 Common - Aldo/keto reductase Daro_1120 199 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 71905739 Common - Protein of unknown function DUF6, transmembrane Daro_0097 104 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 71909462 Common - Ribonuclease PH Daro_3851 183 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 71909091 Common - Phosphoesterase, PA-phosphatase related Daro_3479 17 COG3907 COG3907, PAP2 (acid phosphatase) superfamily protein General function prediction only 71908081 Common - Glycine cleavage system T protein Daro_2463 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 71908390 Common - 2-oxoacid ferredoxin oxidoreductase Daro_2777 94 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 71907296 Common - GGDEF Daro_1665 224 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 71909271 Common - Organic solvent tolerance protein Daro_3659 112 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 71908736 Common - pyridine nucleotide transhydrogenase subunit alpha Daro_3123 114 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 71908271 Common - TraU Daro_2658 26 None None None 71908806 Common - hypothetical protein Daro_3193 8 None None None 71906830 Common - MaoC-like dehydratase Daro_1191 85 COG2030 MaoC, Acyl dehydratase Lipid metabolism 71908325 Common - Extracellular ligand-binding receptor Daro_2712 122 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 71907179 Common - Enoyl-CoA hydratase/isomerase:3-hydroxyacyl-CoA dehydrogenase, C-terminal:3-hydroxyacyl-CoA dehydrogenase, NAD-binding Daro_1547 164 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 71907975 Common - ABC transporter related Daro_2356 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 71907552 Common - hypothetical protein Daro_1923 7 COG5460 COG5460, Uncharacterized conserved protein Function unknown 71908134 Common - Protein of unknown function DUF58 Daro_2518 45 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 71908492 Common - Protein of unknown function DUF188 Daro_2879 97 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 71905949 Common nusG transcription antitermination protein NusG Daro_0307 215 COG0250 NusG, Transcription antiterminator Transcription 71908208 Nonpathogen - hypothetical protein Daro_2595 2 None None None 71909374 Nonpathogen - hypothetical protein Daro_3762 4 None None None 71906840 Common - NLP/P60 Daro_1201 137 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 71907559 Nonpathogen - hypothetical protein Daro_1930 1 None None None 71906211 Common - Sulphate anion transporter Daro_0571 174 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 71907624 Common - Anti-sigma factor antagonist Daro_1995 39 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 71906149 Common - Translation initiation factor IF-1 Daro_0509 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 71909385 Nonpathogen - hypothetical protein Daro_3773 1 None None None 71909113 Common - Phospho-N-acetylmuramoyl-pentapeptide transferase Daro_3501 211 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 71905940 Common - PAS Daro_0298 24 COG2203 FhlA, FOG: GAF domain Signal transduction mechanisms 71906024 Common - Enoyl-CoA hydratase/isomerase Daro_0382 186 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 71907957 Common - IMP dehydrogenase Daro_2338 242 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 71909591 Common - HupJ protein Daro_3981 23 None None None 71908966 Common - GGDEF:EAL:Histidine kinase, HAMP region Daro_3354 159 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 71907944 Common - TraU Daro_2325 26 None None None 71906978 Common - Membrane protein involved in aromatic hydrocarbon degradation Daro_1346 42 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 71906342 Common - Calcium-binding EF-hand Daro_0703 4 COG5126 FRQ1, Ca2+-binding protein (EF-Hand superfamily) Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only 71906480 Common - Beta-lactamase-like Daro_0841 216 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 71909252 Common hemH phosphoribosylaminoimidazole-succinocarboxamide synthase Daro_3640 117 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 71906137 Common - hypothetical protein Daro_0497 30 None None None 71906849 Common - regulatory protein, TetR Daro_1210 52 COG1309 AcrR, Transcriptional regulator Transcription 71906487 Common - Beta-lactamase-like Daro_0848 58 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 71906535 Common - acyl-CoA synthetase Daro_0896 221 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 71906123 Common - Single-strand binding protein Daro_0483 213 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 71908951 Common - 6-phosphogluconate dehydrogenase, NAD-binding Daro_3339 183 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 71908202 Common - Cupin region Daro_2588 13 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 71906474 Nonpathogen - hypothetical protein Daro_0835 1 None None None 71909210 Common - hypothetical protein Daro_3598 9 COG4254 COG4254, Uncharacterized protein conserved in bacteria Function unknown 71905906 Common - regulatory protein, LuxR:Response regulator receiver Daro_0264 211 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 71906189 Common - TRAP transporter solute receptor, TAXI family Daro_0549 76 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 71907733 Common - probable activation/secretion signal peptide protein Daro_2107 69 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 71906143 Common - hypothetical protein Daro_0503 126 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 71907580 Common - scaffold protein Daro_1951 147 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 71907938 Common - hypothetical protein Daro_2319 7 None None None 71906168 Common - GatB/Yqey Daro_0528 151 COG1610 COG1610, Uncharacterized conserved protein Function unknown 71908580 Common - Protein of unknown function DUF599 Daro_2967 24 COG3821 COG3821, Predicted membrane protein Function unknown 71909508 Common - twitching motility protein PilI Daro_3897 20 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 71907922 Common - hypothetical protein Daro_2303 5 COG3212 COG3212, Predicted membrane protein Function unknown 71907144 Nonpathogen - hypothetical protein Daro_1512 3 None None None 71909765 Common - VanZ like protein Daro_4156 15 COG5652 COG5652, Predicted integral membrane protein Function unknown 71908296 Common - Hemerythrin HHE cation binding region Daro_2683 5 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 71906666 Nonpathogen - TonB, C-terminal Daro_1027 2 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 71907756 Common - Formylmethionine deformylase Daro_2132 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 71907824 Common - Cytidine/deoxycytidylate deaminase, zinc-binding region Daro_2202 220 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 71907137 Common - Nitrogenase molybdenum-iron cofactor biosynthesis protein Daro_1505 48 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 71907958 Common - hypothetical protein Daro_2339 8 None None None 71908778 Common - hypothetical protein Daro_3165 2 None None None 71907905 Common - Integrase, catalytic region Daro_2285 153 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 71908143 Common - hypothetical protein Daro_2527 3 None None None 71907540 Common - Helix-turn-helix, AraC type Daro_1911 73 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 71906204 Common - Proton-translocating NADH-quinone oxidoreductase, chain M Daro_0564 208 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 71906900 Common - Glycosyl transferase, group 1 Daro_1262 98 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 71908783 Common - UspA Daro_3170 61 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 71907146 Common - Fe-S cluster assembly protein NifU Daro_1514 147 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 71906130 Common - Amine oxidase:FAD dependent oxidoreductase Daro_0490 70 COG2907 COG2907, Predicted NAD/FAD-binding protein General function prediction only 71906093 Common - Transcriptional coactivator/pterin dehydratase Daro_0453 111 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 71906493 Common - 6-pyruvoyl tetrahydropterin synthase and hypothetical protein Daro_0854 99 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 71909501 Common pyrB aspartate carbamoyltransferase catalytic subunit Daro_3890 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 71907226 Common - generic methyl-transferase Daro_1594 83 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 71909780 Common - acyl carrier protein Daro_4171 45 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 71907284 Common - Integrase, catalytic region Daro_1653 153 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 71908572 Nonpathogen - hypothetical protein Daro_2959 1 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 71907814 Nonpathogen - hypothetical protein Daro_2192 1 None None None 71908955 Common - Acriflavin resistance protein Daro_3343 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 71907729 Common - hypothetical protein Daro_2103 72 COG1360 MotB, Flagellar motor protein Cell motility and secretion 71906015 Common - Phenylacetic acid degradation-related protein:Phenylacetic acid degradation protein PaaD Daro_0373 63 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 71909235 Common - PAS:GGDEF Daro_3623 197 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 71907997 Common - PAS Daro_2378 215 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71907095 Common - protoheme IX farnesyltransferase Daro_1463 169 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 71906869 Common - DNA gyrase subunit A Daro_1230 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 71909720 Common - H+-transporting two-sector ATPase, delta (OSCP) subunit Daro_4111 176 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 71906646 Common - hypothetical protein Daro_1007 42 COG3564 COG3564, Uncharacterized protein conserved in bacteria Function unknown 71909619 Common - PAS Daro_4009 89 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 71906558 Common cysS cysteinyl-tRNA synthetase Daro_0919 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 71906105 Common - Patatin Daro_0465 120 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 71909340 Common - Outer membrane lipoprotein LolB Daro_3728 44 COG3017 LolB, Outer membrane lipoprotein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 71909593 Common - HupH hydrogenase expression protein, C-terminal conserved region Daro_3983 19 None None None 71909244 Common - hypothetical protein Daro_3632 131 COG2860 COG2860, Predicted membrane protein Function unknown 71905826 Common - Hemolysin A Daro_0184 130 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 71907315 Common - Precorrin-3B C17-methyltransferase region Daro_1685 185 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 71905869 Common - Acyl-CoA dehydrogenase, C-terminal:Acyl-CoA dehydrogenase, central region Daro_0227 147 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 71908911 Common - esterase/lipase/thioesterase family active site Daro_3298 69 COG0429 COG0429, Predicted hydrolase of the alpha/beta-hydrolase fold General function prediction only 71906154 Common - thiopurine S-methyltransferase Daro_0514 28 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 71907418 Nonpathogen - hypothetical protein Daro_1788 1 None None None 71908986 Common - Twin-arginine translocation protein TatB Daro_3374 124 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 71906286 Common - putative lipoprotein Daro_0646 13 None None None 71908417 Common - hypothetical protein Daro_2804 20 None None None 71908245 Common - hypothetical protein Daro_2632 79 COG1742 COG1742, Uncharacterized conserved protein Function unknown 71907118 Nonpathogen - hypothetical protein Daro_1486 2 None None None 71905975 Common rpsH 30S ribosomal protein S8 Daro_0333 232 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 71905814 Common - Maf-like protein Daro_0172 195 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 71908861 Common - Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B Daro_3248 31 None None None 71908868 Nonpathogen - hypothetical protein Daro_3255 1 None None None 71906976 Common - putative oxygenase Daro_1344 19 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 71908388 Common - Aldehyde dehydrogenase Daro_2775 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 71908755 Common - DNA repair protein RadC Daro_3142 176 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 71905704 Common - biopolymer transport protein TolA Daro_0062 2 None None None 71907160 Common - regulatory protein, LysR:LysR, substrate-binding Daro_1528 88 COG0583 LysR, Transcriptional regulator Transcription 71905865 Common - PAS Daro_0223 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71907766 Nonpathogen - conserved hypothetical hydrolase/lipase Daro_2143 2 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 71906001 Common - Zinc-containing alcohol dehydrogenase superfamily Daro_0359 114 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 71908312 Common - hypothetical protein Daro_2699 5 COG3311 AlpA, Predicted transcriptional regulator Transcription 71907513 Common - Radical SAM Daro_1884 37 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 71905787 Common - Response regulator receiver:Tetratricopeptide TPR_4 Daro_0145 193 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 71908216 Common - 4Fe-4S ferredoxin, iron-sulfur binding Daro_2603 163 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 71906503 Common - 3-isopropylmalate dehydrogenase Daro_0864 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 71906368 Common - PAS Daro_0729 164 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 71906715 Common - Protein of unknown function DUF159 Daro_1076 83 COG2135 COG2135, Uncharacterized conserved protein Function unknown 71906542 Common - Flavin reductase-like, FMN-binding Daro_0903 109 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 71907844 Nonpathogen - hypothetical protein Daro_2222 2 None None None 71909330 Common - Cell division transporter substrate-binding protein FtsY Daro_3718 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 71906575 Common - Dihydrodipicolinate reductase, bacterial Daro_0936 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 71906742 Common - glutaredoxin family protein Daro_1103 22 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 71908426 Common - hypothetical protein Daro_2813 16 None None None 71909024 Nonpathogen - hypothetical protein Daro_3412 4 None None None 71907223 Common - putative lipase transmembrane protein Daro_1591 46 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 71906834 Common - arginyl-tRNA-protein transferase Daro_1195 85 COG2935 COG2935, Putative arginyl-tRNA:protein arginylyltransferase Posttranslational modification, protein turnover, chaperones 71905658 Common - Pseudouridine synthase, Rsu Daro_0016 203 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 71905951 Common - Ribosomal protein L1, bacterial and chloroplast form Daro_0309 238 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 71906517 Common - Helicase, C-terminal:DEAD/DEAH box helicase, N-terminal Daro_0878 236 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 71908532 Common - 4Fe-4S ferredoxin, iron-sulfur binding Daro_2919 77 COG0348 NapH, Polyferredoxin Energy production and conversion 71908226 Common - hypothetical protein Daro_2613 8 None None None 71908792 Common - hypothetical protein Daro_3179 29 COG4452 CreD, Inner membrane protein involved in colicin E2 resistance Defense mechanisms 71908174 Common - putative ATPase involved in DNA repair Daro_2558 29 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 71908435 Common - AMP-dependent synthetase and ligase Daro_2822 222 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 71908858 Common - 3-phenylpropionate dioxygenase subunit beta Daro_3245 32 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 71906691 Common - PAS:GGDEF Daro_1052 185 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 71906862 Common - Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Daro_1223 212 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 71908454 Common - PAS:GGDEF Daro_2841 196 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 71908308 Common - Helicase, C-terminal:Type III restriction enzyme, res subunit:DEAD/DEAH box helicase, N-terminal Daro_2695 136 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 71908838 Common - hypothetical protein Daro_3225 7 None None None 71907454 Common - ABC transporter related Daro_1825 249 COG3638 COG3638, ABC-type phosphate/phosphonate transport system, ATPase component Inorganic ion transport and metabolism 71906412 Common fliF flagellar MS-ring protein Daro_0773 126 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 71906235 Common mogA molybdenum cofactor biosynthesis protein Daro_0595 186 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 71905769 Common - hypothetical protein Daro_0127 3 None None None 71906356 Common - 4Fe-4S ferredoxin, iron-sulfur binding Daro_0717 84 COG0348 NapH, Polyferredoxin Energy production and conversion 71906184 Common - Leucyl-tRNA synthetase bacterial/mitochondrial, class Ia Daro_0544 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 71909565 Common - PAS:GGDEF:Hemerythrin HHE cation binding region Daro_3954 191 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 71908034 Common - hypothetical protein Daro_2415 12 None None None 71906408 Common - Flagellar FliJ and related Daro_0769 42 COG2882 FliJ, Flagellar biosynthesis chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 71906456 Common - Rieske (2Fe-2S) region Daro_0817 88 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 71907055 Common - Ankyrin Daro_1423 70 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 71908614 Common - oligoribonuclease Daro_3001 88 COG1949 Orn, Oligoribonuclease (3'->5' exoribonuclease) RNA processing and modification 71908044 Common - Integrase, catalytic region Daro_2425 137 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 71909128 Common - NapD Daro_3516 17 COG3062 NapD, Uncharacterized protein involved in formation of periplasmic nitrate reductase Inorganic ion transport and metabolism 71908549 Nonpathogen - hypothetical protein Daro_2936 10 None None None 71908067 Common - Ribosomal protein S15, bacterial chloroplast and mitochondrial type Daro_2449 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 71909126 Common - Nitrate reductase cytochrome c-type subunit (NapB) Daro_3514 41 COG3043 NapB, Nitrate reductase cytochrome c-type subunit Energy production and conversion 71906916 Common - Integration host factor, beta subunit Daro_1281 204 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 71907302 Common - Protein of unknown function DUF214 Daro_1672 34 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 71909474 Common - short chain dehydrogenase Daro_3863 229 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 71906933 Common - recombination factor protein RarA Daro_1298 216 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 71907072 Common - Extracellular ligand-binding receptor Daro_1440 136 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 71907470 Common - ABC transporter related Daro_1841 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 71907615 Common - Alanine racemase region Daro_1986 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 71905676 Common - hypothetical protein Daro_0034 33 None None None 71906816 Common - Secretion protein HlyD Daro_1177 139 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 71907445 Common - Formate dehydrogenase, gamma subunit Daro_1816 64 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 71907683 Nonpathogen - hypothetical protein Daro_2056 1 None None None 71906822 Common - Ankyrin Daro_1183 76 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 71907022 Common - Pirin, N-terminal:Pirin, C-terminal Daro_1390 148 COG1741 COG1741, Pirin-related protein General function prediction only 71909013 Common - Protein of unknown function DUF140 Daro_3401 150 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 71906798 Common - Electron transport complex, RnfABCDGE type, G subunit Daro_1159 54 COG4659 RnfG, Predicted NADH:ubiquinone oxidoreductase, subunit RnfG Energy production and conversion 71906909 Common - Glycosyl transferase, group 1 Daro_1274 60 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 71906262 Common - putative signal transduction protein Daro_0622 43 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 71906752 Common - hypothetical protein Daro_1113 24 COG3470 Tpd, Uncharacterized protein probably involved in high-affinity Fe2+ transport Inorganic ion transport and metabolism 71908662 Common - Cell wall hydrolase/autolysin Daro_3049 177 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 71909555 Common - TonB-dependent receptor Daro_3944 44 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 71907478 Nonpathogen - hypothetical protein Daro_1849 1 None None None 71906915 Common rpsA 30S ribosomal protein S1 Daro_1280 217 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 71909205 Common - Glyceraldehyde 3-phosphate dehydrogenase Daro_3593 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 71907805 Common - hypothetical protein Daro_2183 3 None None None 71906267 Common slmA nucleoid occlusion protein Daro_0627 49 COG1309 AcrR, Transcriptional regulator Transcription 71906248 Common - Peptidase S41A, C-terminal protease Daro_0608 182 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 71908872 Nonpathogen - hypothetical protein Daro_3259 3 None None None 71906111 Common - Sulfatase:Protein of unknown function DUF1705 Daro_0471 64 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 71907758 Common - Thiosulphate-binding protein Daro_2134 95 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 71906193 Common - Pirin, N-terminal Daro_0553 146 COG1741 COG1741, Pirin-related protein General function prediction only 71906008 Common - inner-membrane translocator Daro_0366 164 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 71907693 Common - hypothetical protein Daro_2066 10 None None None 71907528 Common - hypothetical protein Daro_1899 25 COG4254 COG4254, Uncharacterized protein conserved in bacteria Function unknown 71909610 Common - Ferredoxin-type protein NapF Daro_4000 71 COG1245 COG1245, Predicted ATPase, RNase L inhibitor (RLI) homolog General function prediction only 71907246 Common - Mandelate racemase/muconate lactonizing enzyme Daro_1615 72 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 71908291 Common - SlyX Daro_2678 22 COG2900 SlyX, Uncharacterized protein conserved in bacteria Function unknown 71909540 Common - Glycosyl transferase, family 2 Daro_3929 136 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 71908727 Common - Glutamate racemase Daro_3114 186 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 71908979 Nonpathogen - hypothetical protein Daro_3367 2 None None None 71907679 Nonpathogen - hypothetical protein Daro_2051 3 None None None 71907605 Common - PAS:GGDEF Daro_1976 184 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 71909291 Common - Response regulator receiver:LytTr DNA-binding region Daro_3679 140 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 71909390 Common - conserved hypothetical protein, putative transport protein Daro_3778 38 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 71909354 Common - hypothetical protein Daro_3742 21 None None None 71907189 Common - hypothetical protein Daro_1557 9 None None None 71907334 Common - GtrA-like protein Daro_1704 12 COG2246 COG2246, Predicted membrane protein Function unknown 71908301 Nonpathogen - hypothetical protein Daro_2688 1 None None None 71908145 Nonpathogen - hypothetical protein Daro_2529 2 None None None 71908184 Nonpathogen - hypothetical protein Daro_2568 2 None None None 71907879 Common - Heavy metal response regulator Daro_2259 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 71906993 Common - Alpha/beta hydrolase fold Daro_1361 165 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 71906627 Common - ABC-2 Daro_0988 143 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 71908031 Common - hypothetical protein Daro_2412 26 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 71908367 Common - PAS Daro_2754 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71908440 Common - RelA/SpoT protein Daro_2827 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 71908490 Nonpathogen - hypothetical protein Daro_2877 8 None None None 71908117 Common - hypothetical protein Daro_2500 3 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 71906658 Common - Hydantoinase B/oxoprolinase Daro_1019 89 COG0146 HyuB, N-methylhydantoinase B/acetone carboxylase, alpha subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 71907228 Common - Response regulator receiver Daro_1596 223 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 71907522 Common - Protein of unknown function DUF182 Daro_1893 115 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 71908655 Nonpathogen - hypothetical protein Daro_3042 2 None None None 71908555 Nonpathogen - hypothetical protein Daro_2942 3 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 71906725 Common - ATPase, E1-E2 type:Potassium-translocating P-type ATPase, B subunit Daro_1086 232 COG2216 KdpB, High-affinity K+ transport system, ATPase chain B Inorganic ion transport and metabolism 71909522 Common uppP undecaprenyl pyrophosphate phosphatase Daro_3911 201 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 71906374 Common - Response regulator receiver:CheW-like protein Daro_0735 171 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 71906791 Common - Beta-lactamase-like Daro_1152 36 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 71905928 Common - proline-rich region Daro_0286 11 None None None 71907294 Nonpathogen - hypothetical protein Daro_1663 1 None None None 71907960 Common - Streptomyces cyclase/dehydrase Daro_2341 101 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 71906766 Common - heat shock protein 90 Daro_1127 150 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 71906903 Common - UDP-N-acetylglucosamine 2-epimerase Daro_1265 154 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 71906702 Common - regulatory protein GntR, HTH:Aminotransferase, class I and II Daro_1063 216 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 71906176 Common - Class I peptide chain release factor Daro_0536 111 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 71908430 Nonpathogen - hypothetical protein Daro_2817 3 None None None 71907106 Nonpathogen - hypothetical protein Daro_1474 12 COG1433 COG1433, Uncharacterized conserved protein Function unknown 71906396 Common - Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase Daro_0757 74 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 71908916 Common alaS alanyl-tRNA synthetase Daro_3303 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 71908524 Common - Protein of unknown function DUF81 Daro_2911 43 COG0730 COG0730, Predicted permeases General function prediction only 71906724 Common - K+ transporting ATPase, KdpC subunit Daro_1085 95 COG2156 KdpC, K+-transporting ATPase, c chain Inorganic ion transport and metabolism 71907215 Common - probable cytochrome c1 precursor protein Daro_1583 11 None None None 71907103 Common - Cytochrome c oxidase, subunit II:Cytochrome c, class I:Cytochrome C oxidase subunit II, transmembrane region Daro_1471 153 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 71908577 Nonpathogen - hypothetical protein Daro_2964 1 None None None 71906968 Common - hydantoin racemase Daro_1336 43 COG4126 COG4126, Hydantoin racemase Amino acid transport and metabolism 71908467 Common - hypothetical protein Daro_2854 8 None None None 71908410 Common - NAD(P)H dehydrogenase (quinone):NADPH-dependent FMN reductase Daro_2797 70 COG0431 COG0431, Predicted flavoprotein General function prediction only 71908399 Common - putative transmembrane protein Daro_2786 19 None None None 71906661 Common - cytochrome c-552 precursor Daro_1022 13 COG4654 COG4654, Cytochrome c551/c552 Energy production and conversion 71909006 Common - BolA-like protein Daro_3394 110 COG5007 COG5007, Predicted transcriptional regulator, BolA superfamily Transcription 71906945 Common - Helix-turn-helix motif Daro_1311 3 COG1476 COG1476, Predicted transcriptional regulators Transcription 71908924 Common - Protein phosphatase 2C-like Daro_3311 121 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 71907167 Nonpathogen - hypothetical protein Daro_1535 1 None None None 71906827 Common - Protein of unknown function DUF477 Daro_1188 55 COG3762 COG3762, Predicted membrane protein Function unknown 71905653 Common - Glutamate--cysteine ligase GshA Daro_0011 27 None None None 71905726 Common - Protein of unknown function DUF1289 Daro_0084 36 COG3313 COG3313, Predicted Fe-S protein General function prediction only 71907002 Common - hypothetical protein Daro_1370 7 None None None 71909739 Nonpathogen - hypothetical protein Daro_4130 1 None None None 71909735 Nonpathogen - hypothetical protein Daro_4126 1 COG5397 COG5397, Uncharacterized conserved protein Function unknown 71906858 Common - Ribosomal protein L9 Daro_1219 213 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 71908465 Nonpathogen - hypothetical protein Daro_2852 3 None None None 71906587 Common secG preprotein translocase subunit SecG Daro_0948 7 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 71907735 Common - OmpA/MotB Daro_2109 17 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 71905666 Common - hypothetical protein Daro_0024 29 COG4321 COG4321, Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis General function prediction only 71908613 Common - hypothetical protein Daro_3000 21 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 71908048 Nonpathogen - esterase/lipase/thioesterase family active site Daro_2430 14 COG2267 PldB, Lysophospholipase Lipid metabolism 71907287 Common - hypothetical protein Daro_1656 20 None None None 71908713 Common - regulatory protein, LysR:LysR, substrate-binding Daro_3100 113 COG0583 LysR, Transcriptional regulator Transcription 71908932 Common - enoyl-CoA hydratase Daro_3320 179 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 71906069 Common - Response regulator receiver:Transcriptional regulatory protein, C-terminal Daro_0429 209 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 71907297 Common - ATP-binding region, ATPase-like:Histidine kinase A, N-terminal Daro_1667 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71906118 Common - ATP-binding region, ATPase-like:Histidine kinase A, N-terminal Daro_0478 174 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 71906853 Common - hypothetical protein Daro_1214 4 COG3170 FimV, Tfp pilus assembly protein FimV Cell motility and secretion / Intracellular trafficking and secretion 71909800 Common - Sodium/hydrogen exchanger Daro_4191 85 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 71905978 Common rpsE 30S ribosomal protein S5 Daro_0336 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 71907466 Nonpathogen - hypothetical protein Daro_1837 3 None None None 71908001 Common - threonine synthase Daro_2382 148 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 71907666 Common - Excinuclease ABC, C subunit Daro_2038 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 71905711 Common - hypothetical protein Daro_0069 13 COG5341 COG5341, Uncharacterized protein conserved in bacteria Function unknown 71908632 Common - Phasin Daro_3019 16 None None None 71906952 Common - Oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal Daro_1319 249 COG4172 COG4172, ABC-type uncharacterized transport system, duplicated ATPase component General function prediction only 71908543 Nonpathogen - hypothetical protein Daro_2930 1 None None None 71907467 Nonpathogen - hypothetical protein Daro_1838 1 None None None 71909777 Common - Phosphoesterase, PA-phosphatase related Daro_4168 13 None None None 71908786 Common - Rare lipoprotein A Daro_3173 125 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 71909064 Common - suppressor for copper-sensitivity D, putative Daro_3452 45 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 71905661 Common - SMF protein Daro_0019 211 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 71905923 Common - Conserved hypothetical protein 701 Daro_0281 95 COG1981 COG1981, Predicted membrane protein Function unknown 71906593 Common - NADH-quinone oxidoreductase, F subunit Daro_0954 164 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 71909812 Common - ribonuclease P protein Daro_4203 10 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 71906277 Common - Peptidase A24A, prepilin type IV:Peptidase A24A, N-terminal Daro_0637 117 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 71908802 Common - Protein of unknown function DUF88 Daro_3189 83 COG1432 COG1432, Uncharacterized conserved protein Function unknown 71906812 Common - Phosphopantetheine-binding Daro_1173 26 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 71906291 Common - hypothetical protein Daro_0651 14 None None None 71905994 Common - Sporulation related Daro_0352 3 COG3087 FtsN, Cell division protein Cell division and chromosome partitioning 71907772 Common - 5-carboxymethyl-2-hydroxymuconate isomerase Daro_2149 24 COG3232 HpaF, 5-carboxymethyl-2-hydroxymuconate isomerase Amino acid transport and metabolism 71907504 Common - Heavy metal efflux pump CzcA Daro_1875 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 71907484 Common - Radical SAM Daro_1855 42 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 71907123 Nonpathogen - Positive regulator of sigma(E), RseC/MucC Daro_1491 2 COG3086 RseC, Positive regulator of sigma E activity Signal transduction mechanisms 71909132 Nonpathogen - hypothetical protein Daro_3520 2 None None None 71909497 Common - Protein of unknown function YGGT Daro_3886 47 COG0762 COG0762, Predicted integral membrane protein Function unknown 71908567 Nonpathogen - hypothetical protein Daro_2954 2 None None None 71908749 Common - Cytochrome c, class I Daro_3136 25 COG2863 COG2863, Cytochrome c553 Energy production and conversion 71909146 Common glyQ glycyl-tRNA synthetase subunit alpha Daro_3534 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 71909685 Common - Chorismate mutase Daro_4076 30 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 71908092 Common - Heavy metal response regulator Daro_2474 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 71905670 Common - Fmu, rRNA SAM-dependent methyltransferase Daro_0028 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 71906693 Common - selenophosphate synthetase Daro_1054 168 COG0709 SelD, Selenophosphate synthase Amino acid transport and metabolism 71908540 Common - hypothetical protein Daro_2927 17 None None None 71906570 Common - ATP-NAD/AcoX kinase Daro_0931 239 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 71908628 Common - Cytochrome c, class II Daro_3015 16 COG3909 COG3909, Cytochrome c556 Energy production and conversion 71906325 Common - regulatory protein, LuxR:Response regulator receiver Daro_0686 213 COG4566 TtrR, Response regulator Signal transduction mechanisms 71906468 Common - Response regulator receiver:ANTAR Daro_0829 117 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 71909192 Common - regulatory protein, LysR:LysR, substrate-binding Daro_3580 140 COG0583 LysR, Transcriptional regulator Transcription 71906631 Common - Beta-lactamase-like:RNA-metabolising metallo-beta-lactamase Daro_0992 135 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 71909607 Common - Periplasmic protein thiol:disulfide oxidoreductase DsbE Daro_3997 123 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 71905809 Common - putative transmembrane protein Daro_0167 7 COG5473 COG5473, Predicted integral membrane protein Function unknown 71907386 Common - Ribonuclease HII/HIII Daro_1756 206 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 71909443 Common - Alkylhydroperoxidase AhpD core Daro_3832 57 COG2128 COG2128, Uncharacterized conserved protein Function unknown 71907831 Common - hypothetical protein Daro_2209 23 None None None 71907669 Common - Transposase IS116/IS110/IS902 Daro_2041 89 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 71909186 Nonpathogen - hypothetical protein Daro_3574 1 None None None 71909199 Common - hypothetical protein Daro_3587 63 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 71908451 Common - RecJ exonuclease Daro_2838 195 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 71907397 Common - regulatory protein GntR, HTH:GntR, C-terminal Daro_1767 141 COG2186 FadR, Transcriptional regulators Transcription 71908037 Common - glycosyltransferase-like protein Daro_2418 40 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 71906363 Common - chemotaxis sensory transducer Daro_0724 35 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 71909272 Common - Aminoglycoside phosphotransferase Daro_3660 90 COG3178 COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases General function prediction only 71907318 Common - Precorrin-2 C20-methyltransferase Daro_1688 116 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 71908406 Common - Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B Daro_2793 86 COG3384 COG3384, Uncharacterized conserved protein Function unknown 71906996 Nonpathogen - hypothetical protein Daro_1364 2 None None None 71908690 Common - probable transmembrane protein Daro_3077 2 None None None 71909286 Common - Porphobilinogen deaminase Daro_3674 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 71907155 Common - Pyridoxamine 5'-phosphate oxidase-related, FMN-binding Daro_1523 53 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 71906668 Common - ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase, dimerization and phosphoacceptor region Daro_1029 145 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 71906301 Common - Helix-turn-helix, Fis-type Daro_0662 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 71906315 Common - RNA-binding S4 Daro_0676 38 COG2501 COG2501, Uncharacterized conserved protein Function unknown 71909171 Nonpathogen - hypothetical protein Daro_3559 1 None None None 71908259 Nonpathogen - hypothetical protein Daro_2646 2 None None None 71908319 Common - Squalene/phytoene synthase Daro_2706 112 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 71909438 Common - RND efflux system, outer membrane lipoprotein, NodT Daro_3827 108 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 71907891 Nonpathogen - hypothetical protein Daro_2271 1 None None None 71909547 Common - hypothetical protein Daro_3936 19 None None None 71908110 Nonpathogen - hypothetical protein Daro_2493 5 COG1416 COG1416, Uncharacterized conserved protein Function unknown 71907436 Nonpathogen - hypothetical protein Daro_1807 1 None None None 161377473 Common fadB multifunctional fatty acid oxidation complex subunit alpha Daro_2350 162 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 71908235 Common - Protein of unknown function DUF411 Daro_2622 64 COG3019 COG3019, Predicted metal-binding protein General function prediction only 71907349 Common tig trigger factor Daro_1719 212 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 71906608 Common - Response regulator receiver Daro_0969 184 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 71909626 Common - malonate decarboxylase Daro_4016 14 None None None 71905982 Common infA translation initiation factor IF-1 Daro_0340 213 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 71906988 Common - 4-hydroxy-2-ketovalerate aldolase Daro_1356 179 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 71909698 Nonpathogen - hypothetical protein Daro_4089 11 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 71908795 Common - Poly(A) polymerase, PcnB Daro_3182 211 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 71909746 Common - Alpha/beta hydrolase fold Daro_4137 55 COG2267 PldB, Lysophospholipase Lipid metabolism 71906781 Common - CheW-like protein:ATP-binding region, ATPase-like:Signal transducing histidine kinase, homodimeric:Hpt Daro_1142 157 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 71908621 Common - Transglutaminase-like Daro_3008 97 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 71908252 Common - Low molecular weight phosphotyrosine protein phosphatase Daro_2639 9 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 71908647 Common - hypothetical protein Daro_3034 19 None None None 71908028 Common - Glycosyl transferase, group 1 Daro_2409 221 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 71908167 Nonpathogen - hypothetical protein Daro_2551 3 None None None 71907865 Common - hypothetical protein Daro_2245 8 None None None 71909428 Nonpathogen - Monooxygenase component MmoB/DmpM Daro_3817 9 None None None 71906551 Common - hypothetical protein Daro_0912 40 COG3647 COG3647, Predicted membrane protein Function unknown 71907347 Common clpX ATP-dependent protease ATP-binding subunit Daro_1717 231 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 71909164 Common purT phosphoribosylglycinamide formyltransferase 2 Daro_3552 197 COG0027 PurT, Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Nucleotide transport and metabolism 71909668 Common - hypothetical protein Daro_4059 11 COG4402 COG4402, Uncharacterized protein conserved in bacteria Function unknown 71905859 Common - Glutamine amidotransferase, class-II:Glutamate synthase, alpha subunit, C-terminal:Ferredoxin-dependent glutamate synthase:Glutamate synthase, central Daro_0217 202 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 71907941 Common - hypothetical protein Daro_2322 19 COG4959 TraF, Type IV secretory pathway, protease TraF Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 71906126 Common - Cytidyltransferase-related Daro_0486 129 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 71909078 Common - Protein of unknown function DUF214 Daro_3466 171 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 71907920 Common - Protein of unknown function DUF347 Daro_2301 27 COG4705 COG4705, Uncharacterized membrane-anchored protein conserved in bacteria Function unknown 71908230 Common - Heavy metal efflux pump CzcA Daro_2617 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 71908517 Common - YCII-related Daro_2904 69 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 71909455 Common - RNA polymerase, omega subunit Daro_3844 113 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 71908330 Common - OsmC-like protein Daro_2717 53 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 71905734 Common - Carboxyl transferase Daro_0092 144 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 71906282 Common - Signal recognition particle protein Daro_0642 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 71907585 Common - Protein of unknown function DUF528 Daro_1956 43 COG2975 COG2975, Uncharacterized protein conserved in bacteria Function unknown 71908510 Common - 8-amino-7-oxononanoate synthase Daro_2897 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 71906033 Common - Rhs element Vgr protein Daro_0391 58 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 71907859 Common - putative ATPase involved in DNA repair Daro_2237 35 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 71906521 Nonpathogen - general secretion pathway protein H Daro_0882 2 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 71909516 Common - Mg2+ transporter protein, CorA-like Daro_3905 80 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 71906279 Common - type II secretion system protein E:General secretory system II, protein E, N-terminal Daro_0639 216 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 71906253 Common - preprotein translocase subunit SecB Daro_0613 108 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 71907308 Common - Protein of unknown function DUF336 Daro_1678 67 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 71908752 Common - di-heme cytochrome c, class IC Daro_3139 59 COG2863 COG2863, Cytochrome c553 Energy production and conversion 71909792 Common - Hydratase/decarboxylase Daro_4183 62 COG3971 COG3971, 2-keto-4-pentenoate hydratase Secondary metabolites biosynthesis, transport, and catabolism 71908017 Common - Lipopolysaccharide biosynthesis Daro_2398 81 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 71909071 Common - Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal:Hpt Daro_3459 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71909708 Common - ABC transporter related Daro_4099 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 71906051 Common - PAS:GGDEF Daro_0411 187 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 71906610 Common - PAS Daro_0971 216 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 71909769 Common - ABC transporter related Daro_4160 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 71905937 Common - Secretion protein HlyD Daro_0295 157 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 71905749 Common - hypothetical protein Daro_0107 33 COG3154 COG3154, Putative lipid carrier protein Lipid metabolism 71908645 Common - ornithine carbamoyltransferase Daro_3032 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 71909744 Common - Polynucleotide adenylyltransferase region:Metal-dependent phosphohydrolase, HD subdomain Daro_4135 199 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 71907882 Common - hypothetical protein Daro_2262 18 COG5569 COG5569, Uncharacterized conserved protein Function unknown 71908107 Common - ATP-binding region, ATPase-like:Histidine kinase A, N-terminal Daro_2490 220 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 71908904 Common - tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase Daro_3291 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 71909203 Common - transketolase Daro_3591 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 71908373 Common - Benzoate membrane transport protein:Xanthine/uracil/vitamin C permease Daro_2760 62 COG3135 BenE, Uncharacterized protein involved in benzoate metabolism Secondary metabolites biosynthesis, transport, and catabolism 71905855 Common - Pilus assembly protein, PilQ Daro_0213 36 COG3168 PilP, Tfp pilus assembly protein PilP Cell motility and secretion / Intracellular trafficking and secretion 71908668 Common - Rhodanese-like Daro_3055 142 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 71909310 Common - hypothetical protein Daro_3698 7 None None None 71907721 Common - Carbon starvation protein CstA Daro_2095 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 71905960 Common rpsJ 30S ribosomal protein S10 Daro_0318 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 71905847 Common - Auxin Efflux Carrier Daro_0205 124 COG0679 COG0679, Predicted permeases General function prediction only 71905885 Common - Methylmalonyl-CoA mutase, N-terminal:Methylmalonyl-CoA mutase, C-terminal Daro_0243 110 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 71907007 Nonpathogen - hypothetical protein Daro_1375 1 None None None 71909098 Common - hypothetical protein Daro_3486 105 COG0628 PerM, Predicted permease General function prediction only 71908254 Common - regulatory protein, ArsR Daro_2641 67 COG0640 ArsR, Predicted transcriptional regulators Transcription 71905707 Common - Flavin reductase-like, FMN-binding Daro_0065 109 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 71906443 Common - regulatory proteins, IclR Daro_0804 109 COG1414 IclR, Transcriptional regulator Transcription 71906213 Nonpathogen - hypothetical protein Daro_0573 1 None None None 71905870 Common - FAD dependent oxidoreductase:Electron transfer flavoprotein-ubiquinone oxidoreductase Daro_0228 110 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 71907250 Common - acetolactate synthase 1 regulatory subunit Daro_1619 101 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 71906317 Common - phosphate transport regulator-like protein Daro_0678 41 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 71906580 Common - hypothetical protein Daro_0941 21 None None None 71908733 Common - Isocitrate dehydrogenase NADP-dependent, monomeric type Daro_3120 65 COG2838 Icd, Monomeric isocitrate dehydrogenase Energy production and conversion 71908359 Nonpathogen - hypothetical protein Daro_2746 1 None None None 71907914 Common - Helix-turn-helix motif Daro_2294 42 COG1476 COG1476, Predicted transcriptional regulators Transcription 71907099 Common - cytochrome c oxidase, subunit III Daro_1467 158 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 71909366 Common - EAL Daro_3754 163 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 71909450 Common napG quinol dehydrogenase periplasmic component Daro_3839 54 COG1245 COG1245, Predicted ATPase, RNase L inhibitor (RLI) homolog General function prediction only 71907081 Nonpathogen - Ferredoxin Daro_1449 11 COG0633 Fdx, Ferredoxin Energy production and conversion 71909536 Common - Rhodanese-like Daro_3925 142 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 71909115 Common - UDP-N-acetylmuramyl-tripeptide synthetase Daro_3503 209 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 71907371 Common - dTDP-4-dehydrorhamnose reductase Daro_1741 168 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 71909775 Common - CutA1 divalent ion tolerance protein Daro_4166 119 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 71906905 Common - Glycosyl transferase, family 4 Daro_1270 174 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 71907816 Common - TatD-related deoxyribonuclease Daro_2194 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 71905833 Common - GCN5-related N-acetyltransferase Daro_0191 54 COG0456 RimI, Acetyltransferases General function prediction only 71905834 Common - Diaminopimelate epimerase Daro_0192 203 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 71908993 Common hisH imidazole glycerol phosphate synthase subunit HisH Daro_3381 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 71908348 Nonpathogen - hypothetical protein Daro_2735 3 None None None 71907863 Common - hypothetical protein Daro_2242 17 COG0433 COG0433, Predicted ATPase General function prediction only 71905725 Common - Beta-lactamase-like Daro_0083 138 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 71907809 Common - hypothetical protein Daro_2187 8 COG3913 SciT, Uncharacterized protein conserved in bacteria Function unknown 71907608 Common - ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal Daro_1979 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71905852 Common - Type IV pilus assembly protein PilM Daro_0210 80 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 71909359 Common - NLP/P60 Daro_3747 128 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 71906330 Nonpathogen - hypothetical protein Daro_0691 1 None None None 71906260 Common - hypothetical protein Daro_0620 73 COG2717 COG2717, Predicted membrane protein Function unknown 71909463 Common - putative deoxyribonucleotide triphosphate pyrophosphatase Daro_3852 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 71909691 Common - PTS system fructose subfamily IIA component Daro_4082 88 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 71907548 Common - SMC protein, N-terminal Daro_1919 101 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 71907197 Common - Ferredoxin-type protein, NapH/MauN family Daro_1565 61 COG0348 NapH, Polyferredoxin Energy production and conversion 71905942 Common - lactoylglutathione lyase Daro_0300 16 None None None 71906522 Nonpathogen - general secretion pathway protein H Daro_0883 2 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 71907239 Common - hypothetical protein Daro_1607 7 None None None 71907011 Common - hypothetical protein Daro_1379 134 COG1739 COG1739, Uncharacterized conserved protein Function unknown 71907180 Common - Membrane protein involved in aromatic hydrocarbon degradation Daro_1548 77 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 71908947 Common mtnA methylthioribose-1-phosphate isomerase Daro_3335 131 COG0182 COG0182, Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 71908564 Common - hypothetical protein Daro_2951 15 None None None 71908982 Common - Protein of unknown function DUF34 Daro_3370 108 COG0327 COG0327, Uncharacterized conserved protein Function unknown 71909320 Common - hypothetical protein Daro_3708 44 COG4582 COG4582, Uncharacterized protein conserved in bacteria Function unknown 71908021 Common - UDP-N-acetylglucosamine 2-epimerase Daro_2402 152 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 71909352 Common - Thiamine-monophosphate kinase Daro_3740 190 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 71906340 Common - permease Daro_0701 39 COG0701 COG0701, Predicted permeases General function prediction only 71908392 Common - Aromatic-ring-hydroxylating dioxygenase, beta subunit Daro_2779 25 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 71907157 Common - regulatory protein, LysR:LysR, substrate-binding Daro_1525 134 COG0583 LysR, Transcriptional regulator Transcription 71908401 Common - PAS:GGDEF Daro_2788 223 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 71906450 Common - Cytochrome c1 Daro_0811 55 COG2857 CYT1, Cytochrome c1 Energy production and conversion 71906472 Common - GAF:ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase, dimerization and phosphoacceptor region Daro_0833 156 COG3850 NarQ, Signal transduction histidine kinase, nitrate/nitrite-specific Signal transduction mechanisms 71906359 Nonpathogen - TonB, C-terminal Daro_0720 1 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 71906088 Common - Tetrahydrofolate dehydrogenase/cyclohydrolase Daro_0448 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 71906805 Common - Secretion protein HlyD Daro_1166 167 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 71906619 Common - Ferredoxin Daro_0980 181 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 71908593 Common - Host factor Hfq Daro_2980 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 71906673 Common - DSBA oxidoreductase Daro_1034 80 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 71906461 Nonpathogen - hypothetical protein Daro_0822 1 None None None 71909518 Common - Quinate/Shikimate 5-dehydrogenase Daro_3907 224 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 71908273 Common - mating pair stabilization protein Daro_2660 25 None None None 71906681 Nonpathogen - hypothetical protein Daro_1042 1 None None None 71908816 Common hppA membrane-bound proton-translocating pyrophosphatase Daro_3203 98 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 71907506 Common - Outer membrane efflux protein Daro_1877 58 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 71907340 Common - hypothetical protein Daro_1710 65 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 71905751 Common - Peptidase U32 Daro_0109 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 71908352 Nonpathogen - hypothetical protein Daro_2739 3 None None None 71906438 Nonpathogen - hypothetical protein Daro_0799 2 None None None 71906886 Common - NeuB:Antifreeze-like Daro_1248 78 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 71906454 Common - hypothetical protein Daro_0815 120 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 71907063 Common - GCN5-related N-acetyltransferase Daro_1431 5 COG0456 RimI, Acetyltransferases General function prediction only 71909088 Common - Anthranilate phosphoribosyl transferase Daro_3476 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 71908942 Common - Conserved hypothetical protein 2099 Daro_3330 59 COG3164 COG3164, Predicted membrane protein Function unknown 71907408 Common - Fumarate reductase respiratory complex, transmembrane subunit Daro_1778 10 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 71909376 Common - Cation efflux protein Daro_3764 193 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 71909034 Common - Phasin Daro_3422 16 None None None 71905844 Common - hypothetical protein Daro_0202 11 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 71906147 Nonpathogen - hypothetical protein Daro_0507 2 None None None 71907169 Common - regulatory protein, LysR:LysR, substrate-binding Daro_1537 188 COG0583 LysR, Transcriptional regulator Transcription 71909575 Common - Hydrogenase expression/formation protein HypE Daro_3965 168 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 71907563 Common - PAS Daro_1934 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71907955 Common - Phage integrase Daro_2336 109 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 71908738 Common - chemotaxis sensory transducer Daro_3125 22 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 71906074 Common - Protein of unknown function DUF344 Daro_0434 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 71909752 Common - PP-loop Daro_4143 138 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 71906505 Common - hypothetical protein Daro_0866 37 COG3170 FimV, Tfp pilus assembly protein FimV Cell motility and secretion / Intracellular trafficking and secretion 71906923 Common - propable PolB Daro_1288 30 COG3298 COG3298, Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA replication, recombination, and repair 71906425 Common - TPR repeat:Tetratricopeptide TPR_4 Daro_0786 67 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 71907701 Common - hypothetical protein Daro_2074 14 None None None 71906133 Common - hypothetical protein Daro_0493 22 None None None 71906237 Common - Peptidase U62, modulator of DNA gyrase Daro_0597 160 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 71907174 Common - PAS:GGDEF Daro_1542 191 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 71909254 Nonpathogen - hypothetical protein Daro_3642 4 None None None 71907135 Nonpathogen - hypothetical protein Daro_1503 1 None None None 71907646 Common - Acyl carrier protein (ACP) Daro_2018 210 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 71907703 Common - Transport-associated Daro_2076 37 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 71907198 Common - 4Fe-4S ferredoxin, iron-sulfur binding Daro_1566 43 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 71905904 Common - Auxin Efflux Carrier Daro_0262 66 COG0679 COG0679, Predicted permeases General function prediction only 71906479 Common - hypothetical protein Daro_0840 17 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 71906139 Common - hypothetical protein Daro_0499 13 None None None 71908268 Common - hypothetical protein Daro_2655 19 COG4959 TraF, Type IV secretory pathway, protease TraF Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 71906596 Common - NADH dehydrogenase subunit I Daro_0957 191 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 71906533 Common - general secretion pathway protein, ATPase Daro_0894 70 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 71908968 Common - Fimbrial protein pilin:Bacterial general secretion pathway protein H Daro_3356 11 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 71907027 Common - Nitrogen fixation protein NifW Daro_1395 24 None None None 71907142 Common - 4Fe-4S ferredoxin, iron-sulfur binding Daro_1510 29 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 71906489 Nonpathogen - hypothetical protein Daro_0850 1 None None None 71907907 Nonpathogen - hypothetical protein Daro_2287 2 None None None 71906166 Common - RNA polymerase sigma factor RpoD Daro_0526 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 71907149 Common - hypothetical protein Daro_1517 9 None None None 71908125 Nonpathogen - hypothetical protein Daro_2509 2 None None None 71907571 Common - DNA polymerase III, alpha subunit Daro_1942 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 71906125 Common - K+ potassium transporter Daro_0485 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 71908223 Common - 4Fe-4S ferredoxin, iron-sulfur binding Daro_2610 50 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 71906485 Common dapA dihydrodipicolinate synthase Daro_0846 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 71907125 Common - Electron transport complex, RnfABCDGE type, B subunit Daro_1493 118 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 71908094 Common - hypothetical protein Daro_2476 56 COG3781 COG3781, Predicted membrane protein Function unknown 71908140 Common surE stationary phase survival protein SurE Daro_2524 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 71908781 Nonpathogen - hypothetical protein Daro_3168 1 None None None 71906491 Common - hypothetical protein Daro_0852 132 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 71908141 Common - Histone-like nucleoid-structuring protein H-NS Daro_2525 26 COG2916 Hns, DNA-binding protein H-NS General function prediction only 71907631 Common - aromatic amino acid aminotransferase Daro_2002 71 COG1448 TyrB, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 71909327 Common - Twin-arginine translocation pathway signal Daro_3715 11 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 71906175 Common - Conserved hypothetical protein 11 Daro_0535 112 COG2606 EbsC, Uncharacterized conserved protein Function unknown 71906498 Common - hypothetical protein Daro_0859 36 COG2841 COG2841, Uncharacterized protein conserved in bacteria Function unknown 71906946 Common - Resolvase, N-terminal:Resolvase helix-turn-helix region Daro_1312 96 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 71908204 Common - RNA polymerase sigma factor Daro_2590 41 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 71907245 Common - PAS Daro_1614 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71908848 Common - inner-membrane translocator:ABC transporter related Daro_3235 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 71907070 Nonpathogen - hypothetical protein Daro_1438 5 None None None 71909014 Common - ABC transporter related Daro_3402 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 71906420 Common - Flagellar protein FliS Daro_0781 62 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 71908953 Common - PAS:GGDEF Daro_3341 190 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 71906837 Common - Binding-protein-dependent transport systems inner membrane component Daro_1198 175 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 71907933 Nonpathogen - TraL Daro_2314 5 None None None 71906202 Common - Excisionase/Xis, DNA-binding Daro_0562 159 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 71907097 Common - Surfeit locus 1 Daro_1465 72 COG3346 COG3346, Uncharacterized conserved protein Function unknown 71906095 Common - Helix-turn-helix, Fis-type Daro_0455 174 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 71908365 Common - Metal-dependent phosphohydrolase, HD subdomain Daro_2752 111 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 71907042 Common - Dinitrogenase iron-molybdenum cofactor biosynthesis Daro_1410 34 None None None 71909446 Common - Alpha/beta hydrolase fold Daro_3835 117 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 71909506 Common - Response regulator receiver:CheW-like protein:ATP-binding region, ATPase-like:Hpt Daro_3895 225 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 71907765 Nonpathogen - hypothetical protein Daro_2142 1 None None None 71908776 Common - DedA Daro_3163 167 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 71906215 Common - Response regulator receiver:Transcriptional regulatory protein, C-terminal Daro_0575 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 71909242 Nonpathogen - hypothetical protein Daro_3630 1 None None None 71909293 Common - argininosuccinate lyase Daro_3681 229 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 71906651 Nonpathogen - hypothetical protein Daro_1012 1 None None None 71909645 Common - Mitochondrial import inner membrane translocase, subunit Tim44 Daro_4035 32 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 71905817 Common - hypothetical protein Daro_0175 18 None None None 71907360 Nonpathogen - hypothetical protein Daro_1730 1 None None None 71907651 Common - Positive regulator of sigma(E), RseC/MucC Daro_2023 20 COG3086 RseC, Positive regulator of sigma E activity Signal transduction mechanisms 71909563 Nonpathogen - hypothetical protein Daro_3952 1 None None None 71906296 Common - Metal-dependent phosphohydrolase, HD subdomain:Hpt Daro_0657 123 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 71907852 Nonpathogen - hypothetical protein Daro_2230 3 None None None 71909278 Common - Helix-turn-helix, Fis-type Daro_3666 95 COG2901 Fis, Factor for inversion stimulation Fis, transcriptional activator Transcription / DNA replication, recombination, and repair 71909325 Common - hypothetical protein Daro_3713 51 COG3876 COG3876, Uncharacterized protein conserved in bacteria Function unknown 71907727 Common - hypothetical protein Daro_2101 9 None None None 71905699 Common - Phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein Daro_0057 19 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 71909388 Common - hypothetical protein Daro_3776 14 None None None 71905958 Common - Translation elongation factor G:Small GTP-binding protein domain Daro_0316 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 71907972 Common - Acyl-CoA dehydrogenase, C-terminal:Acyl-CoA dehydrogenase, central region:Acyl-CoA dehydrogenase, N-terminal Daro_2353 165 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 71907554 Common - phosphoribosylformylglycinamidine synthase Daro_1925 233 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 71907561 Common - regulatory protein GntR, HTH:Aminotransferase, class I and II Daro_1932 201 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 71907043 Common - 4Fe-4S ferredoxin, iron-sulfur binding Daro_1411 104 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 71909107 Common - Cell division protein FtsQ Daro_3495 80 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 71909616 Common - methylmalonyl-CoA mutase Daro_4006 110 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 71906541 Common - hypothetical protein Daro_0902 48 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 71909058 Common - Camphor resistance CrcB protein Daro_3446 40 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 71909487 Nonpathogen - hypothetical protein Daro_3876 1 None None None 71908729 Common - tRNA/rRNA methyltransferase (SpoU) Daro_3116 22 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 71907625 Common - Radical SAM Daro_1996 73 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 71905644 Common - DNA polymerase III, beta chain Daro_0002 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 71906707 Common - Small GTP-binding protein domain Daro_1068 154 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 71908794 Common - HAD-superfamily hydrolase subfamily IB, PSPase-like:HAD-superfamily subfamily IB, PSPase-like Daro_3181 63 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 71909044 Nonpathogen - hypothetical protein Daro_3432 4 None None None 71908699 Nonpathogen - hypothetical protein Daro_3086 1 None None None 71907162 Common - O-methyltransferase, family 2 Daro_1530 48 None None None 71909230 Common - hypothetical protein Daro_3618 22 COG4995 COG4995, Uncharacterized protein conserved in bacteria Function unknown 71907437 Nonpathogen - hypothetical protein Daro_1808 1 COG2044 COG2044, Predicted peroxiredoxins General function prediction only 71907871 Nonpathogen - hypothetical protein Daro_2251 2 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 71908484 Common - hypothetical protein Daro_2871 15 None None None 71907761 Common - putative cysteine desulfurase Daro_2137 204 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 71909209 Common - OmpA/MotB Daro_3597 132 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 71906548 Common - ABC transporter related Daro_0909 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 71907431 Common - hypothetical protein Daro_1801 18 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 71908885 Common - Blue (type 1) copper domain Daro_3272 24 COG3794 PetE, Plastocyanin Energy production and conversion 71909414 Common - PAS Daro_3803 81 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 71907276 Common - diaminopimelate decarboxylase Daro_1645 218 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 71907829 Common - TIR Daro_2207 10 COG4916 COG4916, Uncharacterized protein containing a TIR (Toll-Interleukin 1-resistance) domain Function unknown 71907209 Common - Electron transport protein SCO1/SenC Daro_1577 105 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 71906832 Nonpathogen - hypothetical protein Daro_1193 3 None None None 71909480 Common ubiB putative ubiquinone biosynthesis protein UbiB Daro_3869 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 71908660 Common - Riboflavin kinase / FAD synthetase:Cytidyltransferase-related Daro_3047 210 COG0196 RibF, FAD synthase Coenzyme metabolism 71909262 Common - hypothetical protein Daro_3650 31 None None None 71906872 Common - histidinol-phosphate aminotransferase Daro_1233 228 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 71908189 Common - hypothetical protein Daro_2573 46 COG4643 COG4643, Uncharacterized protein conserved in bacteria Function unknown 71905737 Common - Protein of unknown function DUF88 Daro_0095 70 COG1432 COG1432, Uncharacterized conserved protein Function unknown 71905687 Common - ABC transporter related Daro_0045 249 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 71909399 Common - Aldehyde dehydrogenase Daro_3787 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 71907587 Common - hypothetical protein Daro_1958 14 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 71906230 Common - Protein of unknown function DUF1345 Daro_0590 40 COG4291 COG4291, Predicted membrane protein Function unknown 71906753 Common - Biopolymer transport protein ExbD/TolR Daro_1114 137 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 71908897 Common - PAS Daro_3284 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71906519 Common - type II secretion system protein Daro_0880 140 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 71906510 Common - tryptophan synthase subunit alpha Daro_0871 211 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 71908323 Common - GCN5-related N-acetyltransferase Daro_2710 102 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 71908476 Common - Succinate dehydrogenase or fumarate reductase, flavoprotein subunit:Succinate dehydrogenase, flavoprotein subunit Daro_2863 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 71909715 Common - ParB-like partition protein Daro_4106 186 COG1475 Spo0J, Predicted transcriptional regulators Transcription 71907378 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase Daro_1748 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 71908804 Common - Cytochrome c oxidase, subunit I Daro_3191 123 COG3256 NorB, Nitric oxide reductase large subunit Inorganic ion transport and metabolism 71906567 Common - Thioredoxin Daro_0928 231 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 71907054 Common - hypothetical protein Daro_1422 34 None None None 71906182 Common holA DNA polymerase III subunit delta Daro_0542 79 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 71909053 Nonpathogen - hypothetical protein Daro_3441 1 None None None 71907986 Common - hypothetical protein Daro_2367 7 None None None 71909156 Common - Prokaryotic diacylglycerol kinase Daro_3544 64 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 71909317 Common - Protein of unknown function DUF815 Daro_3705 89 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 71907695 Common - Aldehyde dehydrogenase Daro_2068 219 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 71909280 Common - phosphoribosylamine--glycine ligase Daro_3668 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 71906327 Common - Na+/H+ antiporter NhaA Daro_0688 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 71906208 Common - Proton-translocating NADH-quinone oxidoreductase, chain M Daro_0568 208 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 71908599 Common - hypothetical protein Daro_2986 87 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 71909505 Common - DNA photolyase, FAD-binding:DNA photolyase, N-terminal Daro_3894 134 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 71909786 Common - probable transmembrane protein Daro_4177 43 COG4258 COG4258, Predicted exporter General function prediction only 71907704 Nonpathogen - Collagen triple helix repeat Daro_2077 1 None None None 71909275 Common - Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 Daro_3663 114 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 71907202 Common - Cytochrome c, class I Daro_1570 55 COG2863 COG2863, Cytochrome c553 Energy production and conversion 71907983 Common eno phosphopyruvate hydratase Daro_2364 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 71907176 Common fadE acyl-CoA dehydrogenase Daro_1544 150 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 71907243 Nonpathogen - Protein of unknown function DUF1555 Daro_1611 2 None None None 71908270 Common - hypothetical protein Daro_2657 26 None None None 71906591 Common - NADH dehydrogenase subunit D Daro_0952 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 71908560 Common - Extracellular ligand-binding receptor Daro_2947 131 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 71905776 Common - hypothetical protein Daro_0134 31 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 71908478 Common - Succinate dehydrogenase, cytochrome b subunit Daro_2865 77 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 71906242 Common - Phosphoglycerate/bisphosphoglycerate mutase Daro_0602 185 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 71909579 Nonpathogen - Hydrogenase expression/formation protein (HUPF/HYPC) Daro_3969 3 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 71909190 Common - hypothetical protein Daro_3578 7 COG5660 COG5660, Predicted integral membrane protein Function unknown 71905803 Nonpathogen - O-antigen polymerase Daro_0161 1 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 71907828 Nonpathogen - hypothetical protein Daro_2206 1 None None None 71906801 Common - electron transport complex protein RnfB Daro_1162 100 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 71909231 Common - hypothetical protein Daro_3619 7 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 71906466 Common - General substrate transporter:Major facilitator superfamily MFS_1 Daro_0827 145 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 71907376 Common - Di-trans-poly-cis-decaprenylcistransferase Daro_1746 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 71906316 Common - Phospholipid/glycerol acyltransferase Daro_0677 36 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 71908796 Common - 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK Daro_3183 195 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 71905648 Common - Silent information regulator protein Sir2 Daro_0006 128 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 71906422 Common - Flagellar protein FlaG protein Daro_0783 40 COG1334 FlaG, Uncharacterized flagellar protein FlaG Cell motility and secretion 71906196 Nonpathogen - hypothetical protein Daro_0556 1 None None None 71907578 Common - Aminotransferase, class V Daro_1949 237 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 71909380 Common - Phospholipase D/Transphosphatidylase Daro_3768 144 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 71907857 Common - hypothetical protein Daro_2235 3 None None None 71907850 Nonpathogen - hypothetical protein Daro_2228 1 None None None 71906926 Common - Nitrogen regulatory protein P-II Daro_1291 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 71907404 Common - Malonyl-CoA decarboxylase Daro_1774 29 None None None 71908340 Common - AAA ATPase, central region:Clp, N terminal Daro_2727 221 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 71906629 Common - Peptidylprolyl isomerase, FKBP-type Daro_0990 133 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 71909549 Common - acetyl-CoA carboxylase biotin carboxylase subunit Daro_3938 224 COG0439 AccC, Biotin carboxylase Lipid metabolism 71907277 Nonpathogen - hypothetical protein Daro_1646 3 None None None 71907652 Common - Peptidase S1C, Do Daro_2024 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 71909808 Common - Cobalamin B12-binding:Radical SAM Daro_4199 115 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 71908485 Common - hypothetical protein Daro_2872 12 None None None 71907691 Common - bacterial regulatory proteins, MerR family Daro_2064 11 COG0789 SoxR, Predicted transcriptional regulators Transcription 71905790 Common cobT nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Daro_0148 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 71906484 Common - PP-loop Daro_0845 211 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 71908069 Common - Ribosome-binding factor A Daro_2451 177 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 71905996 Common - TPR repeat Daro_0354 14 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 71905735 Common - Conserved hypothetical protein 730 Daro_0093 119 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 71907093 Common - hypothetical protein Daro_1461 4 None None None 71907269 Common - membrane protein Daro_1638 40 COG4327 COG4327, Predicted membrane protein Function unknown 71909773 Common - hypothetical protein Daro_4164 56 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 71909296 Common - Modification methylase HemK Daro_3684 231 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 71905721 Common - ABC transporter related Daro_0079 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 71909627 Common - Malonate decarboxylase gamma subunit Daro_4017 28 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 71906303 Common - hypothetical protein Daro_0664 236 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 71909109 Common murC UDP-N-acetylmuramate--L-alanine ligase Daro_3497 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 71907434 Common - Helix-turn-helix, Fis-type Daro_1804 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 71909600 Common - PAS:GGDEF Daro_3990 208 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 71908739 Common - YeeE/YedE Daro_3126 27 None None None 71908918 Common ugpQ cytoplasmic glycerophosphodiester phosphodiesterase Daro_3305 163 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 71905988 Common - Ribosomal protein L17 Daro_0346 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 71907989 Common - hypothetical protein Daro_2370 14 None None None 71905936 Common - Outer membrane efflux protein Daro_0294 89 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 71909617 Common - regulatory protein GntR, HTH:GntR, C-terminal Daro_4007 145 COG1802 GntR, Transcriptional regulators Transcription 71909289 Nonpathogen - Ribonuclease H Daro_3677 1 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 71907714 Common - hypothetical protein Daro_2088 12 None None None 71907366 Common - hypoxanthine-guanine phosphoribosyltransferase Daro_1736 152 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 71908275 Common - hypothetical protein Daro_2662 25 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 71906018 Common - Extracellular ligand-binding receptor Daro_0376 137 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 71906669 Common - regulatory protein, LuxR:Response regulator receiver Daro_1030 213 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 71906496 Common - CBS Daro_0857 120 COG0517 COG0517, FOG: CBS domain General function prediction only 71909742 Common - Protein of unknown function DUF1631 Daro_4133 21 None None None 71906874 Common - DNA ligase Daro_1235 31 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 71908470 Common - dihydrolipoamide dehydrogenase Daro_2857 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 71907628 Common - Radical SAM:Molybdenum cofactor synthesis C-terminal Daro_1999 200 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 71907427 Common - hypothetical protein Daro_1797 33 None None None 71908773 Common - hypothetical protein Daro_3160 15 None None None 71908138 Common - Peptidoglycan-binding LysM:Peptidase M23B Daro_2522 191 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 71908086 Common - Arginase/agmatinase/formiminoglutamase Daro_2468 151 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 71906135 Common - lipoprotein, putative Daro_0495 36 None None None 71909257 Common - integral membrane protein Daro_3645 37 COG5473 COG5473, Predicted integral membrane protein Function unknown 71908893 Common secD preprotein translocase subunit SecD Daro_3280 209 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 71907291 Common - Hemerythrin HHE cation binding region Daro_1660 32 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 71906539 Common - Extracellular ligand-binding receptor Daro_0900 113 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 71907165 Nonpathogen - hypothetical protein Daro_1533 1 None None None 71909389 Nonpathogen - conserved hypothetical protein, putative cox2 cytochrome oxidase subunit 2 Daro_3777 8 None None None 71905681 Common - hypothetical protein Daro_0039 2 None None None 71906022 Common - Phenylacetate-CoA oxygenase, PaaJ subunit Daro_0380 46 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 71909783 Common - hypothetical protein Daro_4174 18 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 71908539 Common - hypothetical protein Daro_2926 4 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 71909570 Common - Nickel-dependent hydrogenase, large subunit Daro_3960 92 COG0374 HyaB, Ni,Fe-hydrogenase I large subunit Energy production and conversion 71909662 Common tolB translocation protein TolB Daro_4053 161 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 71907638 Common - Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase Daro_2010 169 COG0313 COG0313, Predicted methyltransferases General function prediction only 71907420 Common - Rhodanese-like Daro_1790 25 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 71908785 Common - Response regulator receiver Daro_3172 221 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 71909422 Common - Histidine kinase, HAMP region:Bacterial chemotaxis sensory transducer Daro_3811 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 71909589 Common - Hydrogenase expression/synthesis, HypA Daro_3979 100 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 71907946 Common - mating pair stabilization protein Daro_2327 25 None None None 71906477 Common - ABC transporter related Daro_0838 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 71906072 Common - Protein of unknown function DUF548 Daro_0432 52 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 71907128 Common - hypothetical protein Daro_1496 63 COG2914 COG2914, Uncharacterized protein conserved in bacteria Function unknown 71906499 Common - Nucleoside:H+ symporter:Major facilitator superfamily MFS_1 Daro_0860 73 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 71907935 Common - hypothetical protein Daro_2316 7 None None None 71908221 Nonpathogen - hypothetical protein Daro_2608 2 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 71907763 Common - Rhodanese-like Daro_2139 42 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 71907870 Common - RNA-directed DNA polymerase (Reverse transcriptase) Daro_2250 93 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 71907305 Common - Phage integrase Daro_1675 103 COG0582 XerC, Integrase DNA replication, recombination, and repair 71909493 Common - Pilus retraction protein PilT Daro_3882 218 COG5008 PilU, Tfp pilus assembly protein, ATPase PilU Cell motility and secretion / Intracellular trafficking and secretion 71906836 Common - ABC transporter related Daro_1197 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 71906249 Common - Peptidase M23B Daro_0609 186 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 71907040 Common - Leucine rich repeat variant:LRV FeS4 cluster Daro_1408 17 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 71908969 Common - GAF Daro_3357 114 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 71907878 Common - Heavy metal sensor kinase Daro_2258 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71908651 Common - hypothetical protein Daro_3038 7 COG4966 PilW, Tfp pilus assembly protein PilW Cell motility and secretion / Intracellular trafficking and secretion 71909057 Common - PAS:GGDEF Daro_3445 191 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 71909306 Common - OmpA/MotB Daro_3694 144 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 71906439 Nonpathogen - hypothetical protein Daro_0800 1 None None None 71906200 Common - hypothetical protein Daro_0560 21 None None None 71907748 Common - UMUC-like DNA-repair protein Daro_2123 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 71907288 Common - hypothetical protein Daro_1657 21 COG5377 COG5377, Phage-related protein, predicted endonuclease DNA replication, recombination, and repair 71909083 Common rpmA 50S ribosomal protein L27 Daro_3471 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 71906709 Common - Helix-turn-helix, AraC type:ThiJ/PfpI Daro_1070 91 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 71906232 Common - Glucokinase Daro_0592 91 COG0837 Glk, Glucokinase Carbohydrate transport and metabolism 71908725 Common - chemotaxis sensory transducer Daro_3112 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 71906688 Common - hypothetical protein Daro_1049 60 COG2836 COG2836, Uncharacterized conserved protein Function unknown 71908193 Common - NapC/NirT cytochrome c, N-terminal Daro_2579 44 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 71905908 Common - hypothetical protein Daro_0266 22 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 71908123 Common - hypothetical protein Daro_2507 5 None None None 71909075 Common - Protein of unknown function DUF214 Daro_3463 195 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 71909331 Common - Peptidase M16, C-terminal:Peptidase M16, N-terminal Daro_3719 199 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 71906613 Common - Acetate kinase Daro_0974 161 COG0282 ackA, Acetate kinase Energy production and conversion 71907345 Common - Histone-like bacterial DNA-binding protein Daro_1715 201 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 71908941 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Daro_3329 202 COG0388 COG0388, Predicted amidohydrolase General function prediction only 71906449 Common - Cytochrome b/b6, N-terminal:Cytochrome b/b6, C-terminal Daro_0810 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 71907641 Common rpmF 50S ribosomal protein L32 Daro_2013 89 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 71909033 Common - OstA-like protein Daro_3421 29 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 71909568 Nonpathogen - hypothetical protein Daro_3958 1 None None None 71909001 Common - TRAP dicarboxylate transporter, DctM subunit Daro_3389 135 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 71905945 Common - Lysine exporter protein (LYSE/YGGA) Daro_0303 110 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 71909150 Common - Protein of unknown function DUF45 Daro_3538 153 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 71907722 Common - Formate acetyltransferase Daro_2096 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 71908600 Common - TPR repeat Daro_2987 96 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 71908152 Common - UBA/THIF-type NAD/FAD binding fold Daro_2536 16 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 71905686 Common - UDP-N-acetylenolpyruvoylglucosamine reductase Daro_0044 177 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 71907254 Common - GGDEF Daro_1623 19 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 71907818 Common - DNA polymerase III delta prime subunit Daro_2196 216 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 71907551 Common - Glycerol kinase Daro_1922 176 COG0554 GlpK, Glycerol kinase Energy production and conversion 71908906 Common - NUDIX hydrolase Daro_3293 59 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 71905880 Common - Integral membrane protein TerC Daro_0238 122 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 71906527 Common - hypothetical protein Daro_0888 39 None None None 71909314 Common - putative lipoprotein Daro_3702 57 None None None 71907443 Common - selenocysteine synthase Daro_1814 76 COG1921 SelA, Selenocysteine synthase [seryl-tRNASer selenium transferase] Amino acid transport and metabolism 71908335 Common - Aminotransferase, class V Daro_2722 122 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 71907419 Nonpathogen - hypothetical protein Daro_1789 2 None None None 71907196 Common - ABC transporter related Daro_1564 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 71908901 Common - adenylosuccinate lyase Daro_3288 232 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 71907393 Common - 4Fe-4S ferredoxin, iron-sulfur binding:FAD linked oxidase, C-terminal:FAD linked oxidase, N-terminal Daro_1763 199 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 71907736 Common - regulatory protein, MarR Daro_2110 26 COG1846 MarR, Transcriptional regulators Transcription 71906431 Nonpathogen - hypothetical protein Daro_0792 1 None None None 71909535 Common - Protein-L-isoaspartate(D-aspartate) O-methyltransferase:O-methyltransferase, family 3 Daro_3924 158 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 71908944 Common - hypothetical protein Daro_3332 14 None None None 71905742 Common - Acyl-CoA dehydrogenase, C-terminal:Acyl-CoA dehydrogenase, central region:Acyl-CoA dehydrogenase, N-terminal Daro_0100 170 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 71908322 Common - Phosphopantetheine-binding Daro_2709 15 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 71908820 Common - Protein of unknown function DUF343 Daro_3207 107 COG2835 COG2835, Uncharacterized conserved protein Function unknown 71908870 Common - hypothetical protein Daro_3257 46 COG3786 COG3786, Uncharacterized protein conserved in bacteria Function unknown 71907932 Nonpathogen - hypothetical protein Daro_2313 2 None None None 71907991 Common - ABC-2 Daro_2372 33 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 71909533 Common - Carbonic anhydrase, eukaryotic Daro_3922 52 COG3338 Cah, Carbonic anhydrase Inorganic ion transport and metabolism 71909118 Common - methyltransferase Daro_3506 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 71905903 Common - Protein of unknown function DUF107 Daro_0261 10 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 71907232 Common - Protein of unknown function DUF195 Daro_1600 141 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 71906228 Common - hypothetical protein Daro_0588 16 None None None 71907584 Common - Ferredoxin, 2Fe-2S type Daro_1955 60 COG0633 Fdx, Ferredoxin Energy production and conversion 71906704 Common - putative denitrification protein NorE Daro_1065 152 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 71907262 Common - ATP-binding region, ATPase-like:Histidine kinase A, N-terminal Daro_1631 226 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 71907084 Common - Nitrogenase-associated protein Daro_1452 18 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 71907082 Common - Ferredoxin Daro_1450 24 COG0633 Fdx, Ferredoxin Energy production and conversion 71908818 Common adk adenylate kinase Daro_3205 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 71908495 Common - bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase Daro_2882 217 COG1049 AcnB, Aconitase B Energy production and conversion 71906042 Common - AMP-dependent synthetase and ligase:Phospholipid/glycerol acyltransferase Daro_0402 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 71909216 Nonpathogen - hypothetical protein Daro_3604 4 None None None 71909649 Nonpathogen - hypothetical protein Daro_4040 2 None None None 71908355 Common - DNA alkylation repair enzyme Daro_2742 25 COG4912 COG4912, Predicted DNA alkylation repair enzyme DNA replication, recombination, and repair 71906970 Common - Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase-like protein Daro_1338 17 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 71909157 Common - OmpA-like transmembrane domain Daro_3545 10 COG3659 OprB, Carbohydrate-selective porin Cell envelope biogenesis, outer membrane 71909393 Common - Hydratase/decarboxylase Daro_3781 60 COG3971 COG3971, 2-keto-4-pentenoate hydratase Secondary metabolites biosynthesis, transport, and catabolism 71908506 Common - hypothetical protein Daro_2893 85 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 71909599 Common - Ni-Fe hydrogenase, small subunit:Twin-arginine translocation pathway signal Daro_3989 77 COG1740 HyaA, Ni,Fe-hydrogenase I small subunit Energy production and conversion 71908458 Common - hypothetical protein Daro_2845 7 None None None 71908332 Nonpathogen - hypothetical protein Daro_2719 5 None None None 71906577 Common - Carbamoyl-phosphate synthase, small subunit Daro_0938 234 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 71908997 Common - Chromate transporter Daro_3385 104 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 71907811 Common - hypothetical protein Daro_2189 4 None None None 71909349 Common - bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein Daro_3737 229 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 71906659 Common - acetone carboxylase gamma subunit Daro_1020 22 COG4647 AcxC, Acetone carboxylase, gamma subunit Secondary metabolites biosynthesis, transport, and catabolism 71905877 Nonpathogen - hypothetical protein Daro_0235 1 None None None 71906731 Nonpathogen - hypothetical protein Daro_1092 5 None None None 71909139 Common - hypothetical protein Daro_3527 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 71908803 Common - Cytochrome c, class I Daro_3190 36 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 71906091 Common - phosphoribosylaminoimidazole carboxylase ATPase subunit Daro_0451 193 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 71907998 Common - hypothetical protein Daro_2379 221 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 71907841 Common - ParB-like nuclease Daro_2219 76 COG1475 Spo0J, Predicted transcriptional regulators Transcription 71909369 Common - Biotin--acetyl-CoA-carboxylase ligase Daro_3757 177 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 71908667 Nonpathogen - hypothetical protein Daro_3054 1 None None None 71905828 Common - S-adenosyl-L-homocysteine hydrolase Daro_0186 177 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 71907004 Common - IS111A/IS1328/IS1533 Daro_1372 89 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 71905856 Common - type II and III secretion system protein:NolW-like:Secretin/TonB, short N-terminal Daro_0214 109 COG4796 HofQ, Type II secretory pathway, component HofQ Intracellular trafficking and secretion 71908526 Common - hypothetical protein Daro_2913 53 COG3749 COG3749, Uncharacterized protein conserved in bacteria Function unknown 71908740 Common - hypothetical protein Daro_3127 36 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 71908767 Common - hypothetical protein Daro_3154 16 COG3219 COG3219, Uncharacterized protein conserved in bacteria Function unknown 71905728 Common - Pyruvate carboxyltransferase Daro_0086 179 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 71909405 Common - Phenol hydroxylase conserved region Daro_3793 8 None None None 71908394 Common benD 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase Daro_2781 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 71906083 Nonpathogen - hypothetical protein Daro_0443 1 None None None 71906442 Nonpathogen - hypothetical protein Daro_0803 1 None None None 71909693 Common - Phosphoenolpyruvate-protein phosphotransferase Daro_4084 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 71906288 Common - OsmC-like protein Daro_0648 88 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 71909513 Common - Glutamate-1-semialdehyde-2,1-aminomutase Daro_3902 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 71905789 Common - Cobalbumin biosynthesis enzyme Daro_0147 129 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 71906089 Common - 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase Daro_0449 228 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 71906129 Common - Protein of unknown function DUF198 Daro_0489 74 COG1469 COG1469, Uncharacterized conserved protein Function unknown 71909790 Common - Protein of unknown function DUF1615 Daro_4181 18 None None None 71905845 Common - ATP-dependent protease peptidase subunit Daro_0203 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 71906346 Common - YbhB/YbcL Daro_0707 118 COG1881 COG1881, Phospholipid-binding protein General function prediction only 71908019 Nonpathogen - hypothetical protein Daro_2400 11 None None None 71909797 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase Daro_4188 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 71908856 Common - 2-nitropropane dioxygenase, NPD Daro_3243 97 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 71908060 Common - Peptidase S1 and S6, chymotrypsin/Hap Daro_2442 202 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 71909448 Common - RNA polymerase factor sigma-32 Daro_3837 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 71907657 Common - Ribonuclease III, bacterial Daro_2029 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 71909197 Common - Protein of unknown function DUF344 Daro_3585 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 71905921 Common - CDP-6-deoxy-delta-3,4-glucoseen reductase Daro_0279 147 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 71905974 Common - Ribosomal protein S14 Daro_0332 206 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 71908153 Common - hypothetical protein Daro_2537 9 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 71909166 Common - hypothetical protein Daro_3554 7 None None None 71907928 Common - hypothetical protein Daro_2309 13 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 71908513 Common - Dethiobiotin synthase Daro_2900 165 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 71908682 Common - flavodoxin-like protein Daro_3069 105 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 71907921 Common - Phosphoesterase, PA-phosphatase related Daro_2302 39 None None None 71905889 Nonpathogen - Protein of unknown function DUF1555 Daro_0247 2 None None None 71905698 Common purU formyltetrahydrofolate deformylase Daro_0056 219 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 71908100 Nonpathogen - hypothetical protein Daro_2482 1 None None None 71906308 Common - Protein of unknown function DUF224, cysteine-rich region Daro_0669 151 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 71909097 Common - probable phosphatidylethanolamine N-methyltransferase Daro_3485 128 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 71908569 Nonpathogen - Cytochrome c biogenesis protein, transmembrane region Daro_2956 1 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 71907501 Nonpathogen - hypothetical protein Daro_1872 3 None None None 71907323 Common - Precorrin-4 C11-methyltransferase region Daro_1693 202 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 71905760 Common - Glutamyl-tRNA(Gln) amidotransferase A subunit Daro_0118 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 71908310 Common - hypothetical protein Daro_2697 2 None None None 71909707 Common - inner-membrane translocator:ABC transporter related Daro_4098 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 71906414 Common - Helix-turn-helix, Fis-type Daro_0775 222 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 71909756 Common - PTS IIA-like nitrogen-regulatory protein PtsN Daro_4147 137 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 71906762 Common - Phosphate transporter Daro_1123 165 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 71908345 Nonpathogen - hypothetical protein Daro_2732 3 None None None 71906788 Common - putative signal transduction protein Daro_1149 23 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 71907503 Nonpathogen - Streptomyces cyclase/dehydrase Daro_1874 7 COG3427 COG3427, Uncharacterized conserved protein Function unknown 71907662 Common - beta-hexosaminidase Daro_2034 169 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 71906272 Common - hypothetical protein Daro_0632 14 COG2732 COG2732, Barstar, RNAse (barnase) inhibitor Transcription 71906699 Nonpathogen - hypothetical protein Daro_1060 1 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 71907614 Common - regulatory protein, LysR:LysR, substrate-binding Daro_1985 192 COG0583 LysR, Transcriptional regulator Transcription 71907556 Nonpathogen - hypothetical protein Daro_1927 2 None None None 71907442 Common - Twin-arginine translocation pathway signal Daro_1813 80 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 71906633 Common - hypothetical protein Daro_0994 76 None None None 71907591 Common - Phosphoserine phosphatase SerB:HAD-superfamily hydrolase subfamily IB, PSPase-like Daro_1962 148 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 71908070 Common infB translation initiation factor IF-2 Daro_2452 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 71909669 Common ruvB Holliday junction DNA helicase B Daro_4060 218 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 71908010 Common - ABC transporter related Daro_2391 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 71905985 Common - 30S ribosomal protein S11 Daro_0343 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 71908088 Common - 3'-5' exonuclease Daro_2470 15 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 71906609 Common - Response regulator receiver:Metal-dependent phosphohydrolase, HD subdomain Daro_0970 222 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 71906003 Common - NADH:flavin oxidoreductase/NADH oxidase Daro_0361 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 71907395 Common - Protein of unknown function DUF162 Daro_1765 78 COG1556 COG1556, Uncharacterized conserved protein Function unknown 71908557 Common - sulfate adenylyltransferase subunit 2 Daro_2944 124 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 71908320 Common - Amine oxidase Daro_2707 52 COG3349 COG3349, Uncharacterized conserved protein Function unknown 71908692 Common - RDD Daro_3079 48 COG1714 COG1714, Predicted membrane protein/domain Function unknown 71908453 Common - Pyruvate:ferredoxin (flavodoxin) oxidoreductase Daro_2840 119 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 71908811 Common - Cyclic nucleotide-binding Daro_3198 137 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 71906692 Common - Heavy metal transport/detoxification protein Daro_1053 47 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 71909189 Common - TRAP dicarboxylate transporter- DctP subunit Daro_3577 80 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 71908670 Common - Protein of unknown function DUF6, transmembrane Daro_3057 75 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 71906778 Common - Response regulator receiver Daro_1139 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 71907530 Nonpathogen - hypothetical protein Daro_1901 1 None None None 71908676 Common rplS 50S ribosomal protein L19 Daro_3063 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 71908051 Nonpathogen - hypothetical protein Daro_2433 13 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 71908244 Common - ATPase, E1-E2 type:Heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase:Heavy metal translocating P-type ATPase Daro_2631 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 71906982 Common - exporters of the RND superfamily Daro_1350 130 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 71909175 Common - Phosphate ABC transporter, permease protein PstC Daro_3563 223 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 71907462 Common - FecR protein Daro_1833 45 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 71909159 Common - Glycosyl transferase, group 1 Daro_3547 222 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 71906560 Common - Extracellular ligand-binding receptor Daro_0921 127 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 71908162 Common - Helicase, C-terminal Daro_2546 38 COG4646 COG4646, DNA methylase Transcription / DNA replication, recombination, and repair 71907401 Common - PAS:GGDEF Daro_1771 223 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 71908623 Common - Transglutaminase-like Daro_3010 84 COG4196 COG4196, Uncharacterized protein conserved in bacteria Function unknown 71909679 Common - Periplasmic phosphate binding protein Daro_4070 111 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 71907303 Common - Secretion protein HlyD Daro_1673 164 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 71909177 Common - Phosphate transport system permease protein 1 Daro_3565 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 71907889 Nonpathogen - hypothetical protein Daro_2269 1 None None None 71909051 Common - GCN5-related N-acetyltransferase Daro_3439 11 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 71908709 Common - ribonuclease activity regulator protein RraA Daro_3096 97 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 71909130 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase:Pyridine nucleotide-disulphide oxidoreductase, class-II, active site Daro_3518 247 COG3634 AhpF, Alkyl hydroperoxide reductase, large subunit Posttranslational modification, protein turnover, chaperones 71909672 Common - Crossover junction endodeoxyribonuclease RuvC Daro_4063 196 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 71907978 Common - inner-membrane translocator Daro_2359 109 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 71906565 Common - Histidine kinase, HAMP region:Bacterial chemotaxis sensory transducer Daro_0926 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 71907984 Common - 2-dehydro-3-deoxyphosphooctonate aldolase Daro_2365 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 71908843 Common - Alpha/beta hydrolase fold Daro_3230 129 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 71906821 Common - Protein of unknown function DUF411 Daro_1182 53 COG3019 COG3019, Predicted metal-binding protein General function prediction only 71908389 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Daro_2776 42 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 71908615 Common - Peptidase M48, Ste24p Daro_3002 115 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 71907024 Common - Helix-turn-helix, Fis-type Daro_1392 170 COG0583 LysR, Transcriptional regulator Transcription 71907317 Common - Cobalamin (vitamin B12) biosynthesis CbiG protein Daro_1687 67 COG2073 CbiG, Cobalamin biosynthesis protein CbiG Coenzyme metabolism 71907463 Common - TonB-dependent siderophore receptor Daro_1834 116 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 71909319 Common - Protein of unknown function DUF329 Daro_3707 72 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 71908926 Common glcF glycolate oxidase iron-sulfur subunit Daro_3313 172 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 71906893 Common - NAD-dependent epimerase/dehydratase:3-beta hydroxysteroid dehydrogenase/isomerase Daro_1255 232 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 71907491 Common - ABC-type phosphate/phosphonate transport system periplasmic component-like protein Daro_1862 17 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 71909062 Common pyrF orotidine 5'-phosphate decarboxylase Daro_3450 81 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 71906726 Common - potassium-transporting ATPase subunit A Daro_1087 96 COG2060 KdpA, K+-transporting ATPase, A chain Inorganic ion transport and metabolism 71909766 Common - ATPase, E1-E2 type Daro_4157 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 71906167 Common - DNA primase Daro_0527 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 71909168 Common - K+ potassium transporter Daro_3556 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 71909577 Common - Hydrogenase expression/formation protein (HUPF/HYPC) Daro_3967 102 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 71909566 Common - Filamentation induced by cAMP protein Fic Daro_3955 70 COG3177 COG3177, Uncharacterized conserved protein Function unknown 71906329 Common - RNA-directed DNA polymerase (Reverse transcriptase) Daro_0690 93 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 71908537 Common - ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal Daro_2924 186 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 71909152 Common - Extracellular ligand-binding receptor Daro_3540 124 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 71909810 Common - 60 kDa inner membrane insertion protein Daro_4201 212 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 71906799 Common - Electron transport complex, RnfABCDGE type, D subunit Daro_1160 78 COG4658 RnfD, Predicted NADH:ubiquinone oxidoreductase, subunit RnfD Energy production and conversion 71907667 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Daro_2039 202 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 71908700 Common - Para-aminobenzoate synthase, component I Daro_3087 220 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 71909630 Common - alpha subunit of malonate decarboxylase Daro_4020 28 COG4670 COG4670, Acyl CoA:acetate/3-ketoacid CoA transferase Lipid metabolism 71908297 Nonpathogen - hypothetical protein Daro_2684 2 None None None 71907410 Nonpathogen - hypothetical protein Daro_1780 1 None None None 71906416 Common - YcgR Daro_0777 15 COG5581 COG5581, Predicted glycosyltransferase Cell envelope biogenesis, outer membrane 71906113 Common - Excinuclease ABC, A subunit Daro_0473 240 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 71907565 Common - Electron transfer flavoprotein-ubiquinone oxidoreductase Daro_1936 110 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 71906063 Common - Peptidase S13, D-Ala-D-Ala carboxypeptidase C Daro_0423 107 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 71906925 Common nadE NAD synthetase Daro_1290 223 COG0171 NadE, NAD synthase Coenzyme metabolism 71909805 Common - Endoribonuclease L-PSP Daro_4196 15 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 71906856 Common - primosomal replication protein N Daro_1217 19 COG2965 PriB, Primosomal replication protein N DNA replication, recombination, and repair 71905762 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B Daro_0120 211 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 71906290 Common - Ribosomal protein S9 Daro_0650 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 71909312 Common - Dehydrogenase, E1 component Daro_3700 160 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 71908933 Common - Cytochrome c, class I Daro_3321 28 COG4654 COG4654, Cytochrome c551/c552 Energy production and conversion 71906958 Nonpathogen - Metal-dependent phosphohydrolase, HD region Daro_1325 1 COG3481 COG3481, Predicted HD-superfamily hydrolase General function prediction only 71908545 Common - Protein of unknown function DUF181 Daro_2932 45 COG1944 COG1944, Uncharacterized conserved protein Function unknown 71908635 Common - beta-ketothiolase Daro_3022 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 71909021 Nonpathogen - hypothetical protein Daro_3409 5 None None None 71908466 Nonpathogen - hypothetical protein Daro_2853 1 None None None 71909427 Common - Methane/phenol/toluene hydroxylase Daro_3816 17 None None None 71908436 Common - Isochorismate synthase Daro_2823 223 COG1169 MenF, Isochorismate synthase Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism 71908831 Common - general secretion pathway protein G Daro_3218 73 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 71905718 Common - Helix-turn-helix protein, CopG Daro_0076 63 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 71906951 Common - Binding-protein-dependent transport systems inner membrane component Daro_1318 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 71907306 Common - PAS:GGDEF Daro_1676 187 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 71908602 Common ndk nucleoside diphosphate kinase Daro_2989 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 71908257 Common - Lytic transglycosylase, catalytic Daro_2644 35 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 71906771 Nonpathogen - hypothetical protein Daro_1132 5 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 71908717 Nonpathogen - hypothetical protein Daro_3104 5 COG0700 SpmB, Uncharacterized membrane protein Function unknown 71908921 Common - ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal Daro_3308 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71909637 Common - Protein of unknown function DUF710 Daro_4027 42 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 71906780 Common - Sulfate transporter/antisigma-factor antagonist STAS Daro_1141 7 COG3113 COG3113, Predicted NTP binding protein (contains STAS domain) General function prediction only 71906620 Common - NADH ubiquinone oxidoreductase, 20 kDa subunit Daro_0981 50 COG1941 FrhG, Coenzyme F420-reducing hydrogenase, gamma subunit Energy production and conversion 71907417 Common - HDIG Daro_1787 61 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 71908041 Nonpathogen - TPR repeat Daro_2422 7 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 71909552 Common - hypothetical protein Daro_3941 25 None None None 71908665 Common - GGDEF Daro_3052 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 71908024 Common - Glycosyl transferase, group 1 Daro_2405 74 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 71907686 Common - Phospholipase/Carboxylesterase Daro_2059 38 COG3509 LpqC, Poly(3-hydroxybutyrate) depolymerase Secondary metabolites biosynthesis, transport, and catabolism 71905914 Common - inner-membrane translocator Daro_0272 159 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 71906107 Common - hypothetical protein Daro_0467 23 COG3893 COG3893, Inactivated superfamily I helicase DNA replication, recombination, and repair 71907993 Common - Beta-ketoacyl synthase Daro_2374 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 71906173 Common - Protein of unknown function DUF205 Daro_0533 169 COG0344 COG0344, Predicted membrane protein Function unknown 71907783 Common - Secretion protein HlyD Daro_2160 145 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 71907798 Common - Protein of unknown function DUF877 Daro_2176 50 COG3517 COG3517, Uncharacterized protein conserved in bacteria Function unknown 71906769 Common - ABC-1 Daro_1130 175 COG0661 AarF, Predicted unusual protein kinase General function prediction only 71906040 Nonpathogen - hypothetical protein Daro_0399 1 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 71908684 Common - 2-isopropylmalate synthase Daro_3071 213 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 71909182 Common - Ankyrin Daro_3570 98 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 71906641 Common - hypothetical protein Daro_1002 15 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 71907534 Common - CreA Daro_1905 57 COG3045 CreA, Uncharacterized protein conserved in bacteria Function unknown 71907770 Common - Alpha/beta hydrolase fold Daro_2147 152 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 71909016 Common - ATPas Daro_3404 75 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 71908420 Common - Acetyl-CoA hydrolase/transferase Daro_2807 97 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 71907108 Common - Molybdenum ABC transporter, periplasmic binding protein Daro_1476 123 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 71906380 Common flhF flagellar biosynthesis regulator FlhF Daro_0741 85 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 71906851 Common - Electron transfer flavoprotein beta-subunit:Electron transfer flavoprotein, alpha subunit Daro_1212 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 71907483 Common - Protein kinase:Leucine-rich repeat Daro_1854 48 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 71908416 Common - Outer membrane efflux protein Daro_2803 11 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 71906372 Common - Sulfate transporter/antisigma-factor antagonist STAS Daro_0733 14 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 71908468 Common - HDIG Daro_2855 122 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 71907677 Common - hypothetical protein Daro_2049 23 COG3461 COG3461, Uncharacterized conserved protein Function unknown 71908972 Common - Protein phosphatase 2C-like Daro_3360 139 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 71908612 Common rpmE 50S ribosomal protein L31 Daro_2999 206 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 71906530 Common - hypothetical protein Daro_0891 16 None None None 71909351 Common - NusB antitermination factor Daro_3739 148 COG0781 NusB, Transcription termination factor Transcription 71907077 Common - regulatory protein, LuxR:Response regulator receiver Daro_1445 224 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 71906711 Nonpathogen - hypothetical protein Daro_1072 1 None None None 71909614 Common - Carboxyl transferase Daro_4004 212 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 71907752 Common - PAS:GGDEF Daro_2127 174 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 71908116 Common - Resolvase, N-terminal Daro_2499 94 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 71906098 Common - Secretion protein HlyD Daro_0458 130 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 71907057 Common - Urease accessory protein UreF Daro_1425 78 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 71909594 Common - Hydrogenase-1 expression HyaE Daro_3984 15 None None None 71907034 Common - Doubled CXXCH motif Daro_1402 32 None None None 71907855 Nonpathogen - hypothetical protein Daro_2233 4 None None None 71907884 Common - Secretion protein HlyD Daro_2264 174 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 71906198 Common - enoyl-CoA hydratase Daro_0558 180 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 71909740 Common - 5-formyltetrahydrofolate cyclo-ligase Daro_4131 70 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 71909264 Common - Resolvase, N-terminal Daro_3652 141 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 71909412 Common - hypothetical protein Daro_3801 10 None None None 71906217 Common dcd deoxycytidine triphosphate deaminase Daro_0577 149 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 71909364 Common - putative transmembrane protein Daro_3752 35 COG4260 COG4260, Putative virion core protein (lumpy skin disease virus) Function unknown 71909046 Common - Transposase IS116/IS110/IS902 Daro_3434 89 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 71906600 Common - NADH dehydrogenase subunit M Daro_0961 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 71906553 Common - UDP-2,3-diacylglucosamine hydrolase Daro_0914 76 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 71905709 Common - aromatic acid decarboxylase Daro_0067 152 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 71908304 Common - hypothetical protein Daro_2691 7 None None None 71906990 Common - Rieske (2Fe-2S) region Daro_1358 66 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 71908302 Nonpathogen - hypothetical protein Daro_2689 1 None None None 71908827 Common - Protein of unknown function DUF181 Daro_3214 52 COG1944 COG1944, Uncharacterized conserved protein Function unknown 71909653 Common - inner-membrane translocator Daro_4044 75 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 71907915 Common - Protein of unknown function DUF6, transmembrane Daro_2296 58 COG2510 COG2510, Predicted membrane protein Function unknown 71909392 Common - 4-oxalocrotonate tautomerase Daro_3780 20 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 71908801 Common - hypothetical protein Daro_3188 6 None None None 71908877 Common - Cyanophycin synthetase Daro_3264 66 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 71907012 Nonpathogen - hypothetical protein Daro_1380 1 None None None 71906817 Common - Heavy metal efflux pump CzcA Daro_1178 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 71909027 Nonpathogen - ATP-binding region, ATPase-like Daro_3415 6 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71909100 Common - preprotein translocase subunit SecA Daro_3488 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 71906514 Common - Colicin V production protein Daro_0875 50 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 71907961 Common smpB SsrA-binding protein Daro_2342 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 71908583 Common - hypothetical protein Daro_2970 2 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 71906452 Common - ClpXP protease specificity-enhancing factor Daro_0813 64 COG2969 SspB, Stringent starvation protein B General function prediction only 71908057 Common - TPR repeat:Tetratricopeptide TPR_3:Tetratricopeptide TPR_4 Daro_2439 108 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 71908958 Common - Cytochrome c, class I Daro_3346 27 COG4654 COG4654, Cytochrome c551/c552 Energy production and conversion 71909587 Common - Hydrogenase maturation protein HypF Daro_3977 113 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 71906975 Nonpathogen - hypothetical protein Daro_1343 1 None None None 71906210 Common - PhnA protein Daro_0570 95 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 71907475 Common - Flagellar basal body-associated protein FliL Daro_1846 20 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 71908233 Common - Outer membrane efflux protein Daro_2620 15 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 71907861 Common - hypothetical protein Daro_2239 6 None None None 71909491 Nonpathogen - hypothetical protein Daro_3880 1 None None None 71905675 Common - Primosomal protein n Daro_0033 211 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 71909520 Common - Ribonuclease II Daro_3909 109 COG0557 VacB, Exoribonuclease R Transcription 71906884 Common - surface polysaccharide biosynthesis protein, transferase Daro_1246 32 COG3980 spsG, Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase Cell envelope biogenesis, outer membrane 71909601 Common - Heme exporter protein CcmA Daro_3991 243 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 71906263 Common - CBS Daro_0623 180 COG0517 COG0517, FOG: CBS domain General function prediction only 71907049 Common - hypothetical protein Daro_1417 13 None None None 71906845 Common - Protein of unknown function DUF140 Daro_1206 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 71907133 Common - Nitrogenase MoFe cofactor biosynthesis protein NifE Daro_1501 54 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 71906152 Common - regulatory proteins, AsnC/Lrp Daro_0512 155 COG1522 Lrp, Transcriptional regulators Transcription 71907482 Common - hypothetical protein Daro_1853 18 None None None 71908002 Nonpathogen - hypothetical protein Daro_2383 3 None None None 71907525 Common - PAS Daro_1896 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71909499 Common - Competence protein ComEA helix-hairpin-helix region Daro_3888 124 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 71905969 Common - 50S ribosomal protein L29 Daro_0327 83 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 71908866 Common - Protein of unknown function DUF192 Daro_3253 86 COG1430 COG1430, Uncharacterized conserved protein Function unknown 71909081 Common - Peptidylprolyl isomerase, FKBP-type Daro_3469 152 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 71908369 Common - hypothetical protein Daro_2756 29 COG3394 COG3394, Uncharacterized protein conserved in bacteria Function unknown 71907909 Nonpathogen - hypothetical protein Daro_2289 2 None None None 71908063 Common - hypothetical protein Daro_2445 14 None None None 71908854 Common - Extracellular ligand-binding receptor Daro_3241 114 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 71906349 Common - NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR Daro_0710 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 71907596 Common - UDP-glucose/GDP-mannose dehydrogenase Daro_1967 201 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 71909529 Common - Secretion protein HlyD Daro_3918 164 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 71906755 Common - TonB, C-terminal Daro_1116 43 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 71908317 Common - Phage integrase Daro_2704 100 COG0582 XerC, Integrase DNA replication, recombination, and repair 71907316 Common - Cobalamin (vitamin B12) biosynthesis CbiG protein Daro_1686 33 COG2073 CbiG, Cobalamin biosynthesis protein CbiG Coenzyme metabolism 71906500 Common - isopropylmalate isomerase large subunit Daro_0861 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 71908427 Common - Cytochrome B561, bacterial Daro_2814 46 COG3658 COG3658, Cytochrome b Energy production and conversion 71909333 Common - Peptidase M16, C-terminal:Peptidase M16, N-terminal Daro_3721 171 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 71906459 Common - Protein kinase:Protein phosphatase 2C-like Daro_0820 149 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 71908131 Common - aspartate kinase Daro_2515 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 71908022 Common - Polysaccharide deacetylase Daro_2403 102 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 71909358 Common - hypothetical protein Daro_3746 11 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 71906839 Common - extracellular solute-binding protein, family 1 Daro_1200 112 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 71908984 Common - Glutamine amidotransferase, class-II Daro_3372 72 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 71906284 Common - Prolyl-tRNA synthetase, bacterial Daro_0644 249 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 71905893 Common - inner-membrane translocator Daro_0251 153 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 71907510 Common - hypothetical protein Daro_1881 26 None None None 161377474 Common - phospho-2-dehydro-3-deoxyheptonate aldolase Daro_1964 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 71909073 Common - Secretion protein HlyD Daro_3461 179 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 71906863 Common - extracellular solute-binding protein, family 5 Daro_1224 132 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 71906648 Common - Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase A, N-terminal Daro_1009 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71906792 Common - hypothetical protein Daro_1153 23 None None None 71906544 Common - Hydratase/decarboxylase Daro_0905 67 COG3971 COG3971, 2-keto-4-pentenoate hydratase Secondary metabolites biosynthesis, transport, and catabolism 71908525 Common - Nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin-like:Nitrite and sulphite reductase 4Fe-4S region Daro_2912 171 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 71906375 Common - Response regulator receiver Daro_0736 216 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 71909702 Common - TonB, C-terminal Daro_4093 49 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 71906386 Nonpathogen - hypothetical protein Daro_0747 3 COG2747 FlgM, Negative regulator of flagellin synthesis (anti-sigma28 factor) Transcription / Cell motility and secretion / Intracellular trafficking and secretion 71906694 Common - TonB-dependent siderophore receptor Daro_1055 104 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 71908447 Common - Histidine kinase, HAMP region:Bacterial chemotaxis sensory transducer Daro_2834 148 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 71908035 Common - Glycosyl transferase, group 1 Daro_2416 174 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 71907965 Common queF 7-cyano-7-deazaguanine reductase Daro_2346 104 COG2904 COG2904, Uncharacterized protein conserved in bacteria Function unknown 71907079 Common - ADP-ribosylation/Crystallin J1 Daro_1447 56 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 71907225 Common - Ribonuclease H Daro_1593 176 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 71905962 Common rplD 50S ribosomal protein L4 Daro_0320 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 71906581 Common - hypothetical protein Daro_0942 94 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 71907868 Common - hypothetical protein Daro_2248 77 COG2119 COG2119, Predicted membrane protein Function unknown 71909475 Common - Twin-arginine translocation pathway signal Daro_3864 68 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 71909716 Nonpathogen - ATP synthase protein I Daro_4107 1 COG3312 AtpI, F0F1-type ATP synthase, subunit I Energy production and conversion 71906734 Common - hypothetical protein Daro_1095 8 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 71908519 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Daro_2906 153 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 71907897 Common - protein-S-isoprenylcysteine methyltransferase Daro_2277 24 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 71905655 Common - ABC transporter related Daro_0013 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 71906944 Nonpathogen - hypothetical protein Daro_1310 2 None None None 71907038 Common - Hemerythrin Daro_1406 19 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 71909468 Common - SEC-C motif Daro_3857 88 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 71905934 Common - regulatory protein, LysR:LysR, substrate-binding Daro_0292 153 COG0583 LysR, Transcriptional regulator Transcription 71908472 Common kgd alpha-ketoglutarate decarboxylase Daro_2859 147 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 71909259 Common - hypothetical protein Daro_3647 11 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 71906136 Common - Short-chain dehydrogenase/reductase SDR Daro_0496 187 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 71907006 Common - hypothetical protein Daro_1374 6 None None None 71906164 Common - Extracellular ligand-binding receptor Daro_0524 122 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 71908880 Common - regulatory proteins, AsnC/Lrp Daro_3267 50 COG1522 Lrp, Transcriptional regulators Transcription 71907211 Common - PAS:GGDEF Daro_1579 193 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 71905744 Common - regulatory protein, MerR Daro_0102 101 COG0789 SoxR, Predicted transcriptional regulators Transcription 71908891 Common tgt queuine tRNA-ribosyltransferase Daro_3278 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 71907148 Nonpathogen - hypothetical protein Daro_1516 1 None None None 71907937 Common - periplasmic thiol:disulfide interchange protein Daro_2318 45 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 71908277 Common - hypothetical protein Daro_2664 22 None None None 71908721 Common - regulatory protein, LuxR:Response regulator receiver Daro_3108 221 COG4566 TtrR, Response regulator Signal transduction mechanisms 71906320 Common - 4Fe-4S ferredoxin, iron-sulfur binding Daro_0681 95 COG0348 NapH, Polyferredoxin Energy production and conversion 71906433 Nonpathogen - hypothetical protein Daro_0794 2 None None None 71908956 Common - Secretion protein HlyD Daro_3344 146 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 71909481 Common - SNF2-related:Helicase, C-terminal:SWIM Zn-finger Daro_3870 136 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 71907731 Common - PAS Daro_2105 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71909561 Common - Hemerythrin HHE cation binding region Daro_3950 10 None None None 71907876 Common - Cd(II)/Pb(II)-responsive transcriptional regulator Daro_2256 133 COG0789 SoxR, Predicted transcriptional regulators Transcription 71906941 Common - Restriction modification system DNA specificity domain Daro_1307 72 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 71909345 Common - translation-associated GTPase Daro_3733 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 71908912 Common - Phosphoglucomutase/phosphomannomutase C terminal:Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I:Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II:Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III Daro_3299 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 71908883 Common - Cytochrome d1, heme region Daro_3270 39 COG3391 COG3391, Uncharacterized conserved protein Function unknown 71906475 Common - hypothetical protein Daro_0836 45 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 71908135 Common - Transglutaminase-like Daro_2519 109 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 71907952 Common - hypothetical protein Daro_2333 7 None None None 71908190 Common - hypothetical protein Daro_2574 7 None None None 71907622 Common - CHASE2:Stage II sporulation E Daro_1993 128 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 71907508 Common - ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal Daro_1879 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71909383 Nonpathogen - hypothetical protein Daro_3771 1 None None None 71907994 Nonpathogen - hypothetical protein Daro_2375 2 None None None 71906494 Common - hypothetical protein Daro_0855 22 COG0731 COG0731, Fe-S oxidoreductases Energy production and conversion 71907264 Common - DNA polymerase III, epsilon subunit Daro_1633 197 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 71909410 Common - Helix-turn-helix, Fis-type Daro_3798 172 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 71907633 Common - Low molecular weight phosphotyrosine protein phosphatase Daro_2004 139 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 71908680 Common - hypothetical protein Daro_3067 8 None None None 71906278 Common - type II secretion system protein Daro_0638 150 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 71908964 Common - Response regulator receiver:Transcriptional regulatory protein, C-terminal Daro_3352 215 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 71905990 Common - ABC transporter, transmembrane region:ABC transporter related Daro_0348 249 COG5265 ATM1, ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components Posttranslational modification, protein turnover, chaperones 71907050 Common - hypothetical protein Daro_1418 18 None None None 71907813 Common - hypothetical protein Daro_2191 10 None None None 71907648 Nonpathogen - hypothetical protein Daro_2020 1 None None None 71906020 Common - Phenylacetic acid degradation B Daro_0378 38 COG3460 COG3460, Uncharacterized enzyme of phenylacetate metabolism Secondary metabolites biosynthesis, transport, and catabolism 71907193 Common - thioredoxin Daro_1561 184 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 71909213 Common - hypothetical protein Daro_3601 24 COG5412 COG5412, Phage-related protein Function unknown 71909664 Common - Biopolymer transport protein ExbD/TolR Daro_4055 127 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 71906191 Common - PAS Daro_0551 226 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71906964 Common - hypothetical protein Daro_1332 23 COG5631 COG5631, Predicted transcription regulator, contains HTH domain (MarR family) Transcription 71908205 Common - putative transmembrane hydrogenase cytochrome B-type subunit oxidoreductase protein Daro_2591 51 COG4117 COG4117, Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) Energy production and conversion 71905947 Common tuf elongation factor Tu Daro_0305 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 71906424 Common - TPR repeat Daro_0785 56 COG3914 Spy, Predicted O-linked N-acetylglucosamine transferase, SPINDLY family Posttranslational modification, protein turnover, chaperones 71907636 Common - Rieske (2Fe-2S) region Daro_2008 36 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 71906255 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase Daro_0615 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 71908195 Common - hypothetical protein Daro_2581 10 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 71908771 Common - MscS Mechanosensitive ion channel Daro_3158 196 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 71908763 Common - RNA polymerase sigma factor Daro_3150 36 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 71906031 Common - Alpha-2-macroglobulin, N-terminal:Alpha-2-macroglobulin, N-terminal 2 Daro_0389 79 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 71906537 Common - regulatory protein GntR, HTH:GntR, C-terminal Daro_0898 106 COG1802 GntR, Transcriptional regulators Transcription 71906569 Common hrcA heat-inducible transcription repressor Daro_0930 150 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 71906736 Common - luciferase-like Daro_1097 113 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 71907204 Common - regulatory protein, LuxR:Response regulator receiver Daro_1572 218 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 71908653 Common - General secretion pathway protein H Daro_3040 8 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 71909260 Common - AP endonuclease, family 1:Exodeoxyribonuclease III xth Daro_3648 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 71906429 Nonpathogen - hypothetical protein Daro_0790 1 None None None 71909572 Common - Helix-turn-helix, Fis-type Daro_3962 201 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 71906955 Common - hypothetical protein Daro_1322 3 COG3655 COG3655, Predicted transcriptional regulator Transcription 71907543 Common - Alpha/beta hydrolase fold Daro_1914 11 COG2267 PldB, Lysophospholipase Lipid metabolism 71909395 Common - acetaldehyde dehydrogenase Daro_3783 37 COG4569 MhpF, Acetaldehyde dehydrogenase (acetylating) Secondary metabolites biosynthesis, transport, and catabolism 71907712 Nonpathogen - hypothetical protein Daro_2086 4 None None None 71909220 Common - PAAR Daro_3608 25 COG4104 COG4104, Uncharacterized conserved protein Function unknown 71909781 Common - transmembrane protein Daro_4172 17 COG4648 COG4648, Predicted membrane protein Function unknown 71908128 Nonpathogen - hypothetical protein Daro_2512 1 None None None 71907069 Common - inner-membrane translocator Daro_1437 107 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 71907698 Common - 6-phosphogluconolactonase Daro_2071 121 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 71909321 Common - Dephospho-CoA kinase Daro_3709 203 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 71906206 Common - NADH-Ubiquinone oxidoreductase (complex I), chain 5/L, N-terminal:NADH/Ubiquinone/plastoquinone (complex I) Daro_0566 202 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 71905774 Common - TonB-dependent receptor Daro_0132 116 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 71906616 Nonpathogen - hypothetical protein Daro_0977 2 None None None 71908563 Common - Sigma-70 region 2 Daro_2950 142 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 71906234 Common - hypothetical protein Daro_0594 5 None None None 71906447 Common recR recombination protein RecR Daro_0808 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 71908961 Common - Response regulator receiver Daro_3349 209 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 71907826 Common - hypothetical protein Daro_2204 2 None None None 71908342 Common - Molybdopterin biosynthesis MoaE Daro_2729 160 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 71906564 Common - Cyclic nucleotide-binding:Protein kinase Daro_0925 154 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 71908798 Common - Ketopantoate hydroxymethyltransferase Daro_3185 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 71908337 Nonpathogen - hypothetical protein Daro_2724 1 None None None 71909202 Common - hypothetical protein Daro_3590 4 None None None 71907800 Common - putative lipoprotein Daro_2178 4 COG4105 ComL, DNA uptake lipoprotein General function prediction only 71909135 Common - Resolvase, N-terminal:Resolvase helix-turn-helix region Daro_3523 96 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 71907374 Common pyrH uridylate kinase Daro_1744 238 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 71906823 Common - K+ potassium transporter Daro_1184 89 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 71906880 Common - DegT/DnrJ/EryC1/StrS aminotransferase Daro_1242 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 71907218 Common - ATP-binding region, ATPase-like:Histidine kinase A, N-terminal Daro_1586 140 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 71909420 Common - Short-chain dehydrogenase/reductase SDR Daro_3809 70 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 71907062 Common - Urease accessory protein UreD Daro_1430 83 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 71906319 Common - C4-dicarboxylate transporter/malic acid transport protein Daro_0680 75 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 71908098 Common - Heavy metal efflux pump CzcA Daro_2480 178 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 71909055 Common - Cold-shock protein, DNA-binding:Protein of unknown function DUF1294 Daro_3443 51 COG3326 COG3326, Predicted membrane protein Function unknown 71909370 Common - Helix-turn-helix, Fis-type:Nitrogen regulation protein NR(I) Daro_3758 222 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 71907629 Nonpathogen - hypothetical protein Daro_2000 1 None None None 71905646 Common - Histidine triad (HIT) protein Daro_0004 211 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 71909382 Common - PAS:GGDEF Daro_3770 186 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 71906027 Common - Phenylacetic acid degradation protein PaaY Daro_0385 203 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 71909233 Common - GGDEF Daro_3621 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 71909431 Common - Methane/phenol/toluene hydroxylase:YHS Daro_3820 19 None None None 71906170 Common - Peptidase M22, glycoprotease Daro_0530 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 71907194 Common - putative ABC-2 type transport system permease protein Daro_1562 45 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 71906706 Nonpathogen - FeoA Daro_1067 2 None None None 71907364 Common - NAD-dependent DNA ligase Daro_1734 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 71908211 Common - hypothetical protein Daro_2598 33 None None None 71909771 Common - 2-phosphosulfolactate phosphatase Daro_4162 26 COG2045 COG2045, Phosphosulfolactate phosphohydrolase and related enzymes Coenzyme metabolism / General function prediction only 71907688 Common - hypothetical protein Daro_2061 11 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 71907902 Nonpathogen - hypothetical protein Daro_2282 6 None None None 71906070 Common - ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal Daro_0430 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71906464 Common - Nitrate transporter Daro_0825 92 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 71909453 Common - FAD dependent oxidoreductase Daro_3842 121 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 71908315 Nonpathogen - hypothetical protein Daro_2702 2 None None None 71908808 Nonpathogen - hypothetical protein Daro_3195 6 None None None 71905693 Common - Protein of unknown function DUF526 Daro_0051 52 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 71905819 Common - acetyl-CoA synthetase Daro_0177 202 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 71909542 Common - Glucosamine-fructose-6-phosphate aminotransferase, isomerising Daro_3931 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 71908949 Common - Cation efflux protein Daro_3337 188 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 71908250 Common - Anion-transporting ATPase Daro_2637 97 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 71909008 Common - ABC transporter related Daro_3396 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 71907406 Common sdhB succinate dehydrogenase iron-sulfur subunit Daro_1776 191 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 71909760 Common - Regulatory protein RecX Daro_4151 52 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 71909269 Common - Pyridoxal phosphate biosynthetic protein PdxA Daro_3657 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 71908384 Common - inner-membrane translocator Daro_2771 149 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 71905780 Common - Periplasmic binding protein Daro_0138 166 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 71906011 Nonpathogen - hypothetical protein Daro_0369 3 None None None 71908076 Common - Lipid A biosynthesis, N-terminal Daro_2458 23 COG3952 COG3952, Predicted membrane protein Function unknown 71905901 Common - Forkhead-associated Daro_0259 13 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 71908604 Common - TRAP dicarboxylate transporter, DctM subunit Daro_2991 126 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 71907047 Common - Nitrogenase iron protein Daro_1415 99 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 71907279 Common - Histone-like bacterial DNA-binding protein Daro_1648 187 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 71909642 Common - ABC transporter related Daro_4032 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 71906930 Common - Cell divisionFtsK/SpoIIIE Daro_1295 198 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 71909298 Common - Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal Daro_3686 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71907178 Common - DegV Daro_1546 25 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 71905757 Common - Rod shape-determining protein MreC, subtype Daro_0115 140 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 71906310 Common - Aldehyde dehydrogenase Daro_0671 143 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 71907320 Common cbiD cobalt-precorrin-6A synthase Daro_1690 83 COG1903 CbiD, Cobalamin biosynthesis protein CbiD Coenzyme metabolism 71906507 Common truA tRNA pseudouridine synthase A Daro_0868 233 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 71909028 Nonpathogen - Prokaryotic N-terminal methylation site Daro_3416 7 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 71906524 Nonpathogen - hypothetical protein Daro_0885 6 COG4967 PilV, Tfp pilus assembly protein PilV Cell motility and secretion / Intracellular trafficking and secretion 71907650 Common - RNA polymerase sigma factor RpoE Daro_2022 170 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 71909240 Common - fructose-1,6-bisphosphatase Daro_3628 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 71909283 Common - HemY, N-terminal Daro_3671 45 COG3071 HemY, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 71906876 Common - dTDP-glucose 4,6-dehydratase Daro_1237 232 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 71905703 Common - ABC transporter related Daro_0061 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 71905733 Common - Negative transcriptional regulator Daro_0091 60 COG2808 PaiB, Transcriptional regulator Transcription 71908062 Nonpathogen - hypothetical protein Daro_2444 1 None None None 71906749 Common - Iron permease FTR1 Daro_1110 23 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 71906094 Common - CBS Daro_0454 16 None None None 71905771 Common - Methionine biosynthesis MetW Daro_0129 71 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 71909347 Common - spermidine synthase Daro_3735 109 COG4262 COG4262, Predicted spermidine synthase with an N-terminal membrane domain General function prediction only 71907912 Common - hypothetical protein Daro_2292 7 None None None 71907327 Common - cobalt transport protein CbiM Daro_1697 47 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 71909695 Common - Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal Daro_4086 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71906158 Nonpathogen - hypothetical protein Daro_0518 1 None None None 71905850 Common - Frataxin-like Daro_0208 40 COG1965 CyaY, Protein implicated in iron transport, frataxin homolog Inorganic ion transport and metabolism 71908865 Common - Chorismate lyase Daro_3252 26 COG3161 UbiC, 4-hydroxybenzoate synthetase (chorismate lyase) Coenzyme metabolism 71906151 Common - 2-isopropylmalate synthase Daro_0511 211 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 71908898 Common - Response regulator receiver:Metal-dependent phosphohydrolase, HD subdomain Daro_3285 224 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 71907227 Common - Beta-lactamase-like Daro_1595 189 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 71907710 Common - hypothetical protein Daro_2084 9 None None None 71906212 Common - Helix-turn-helix protein, CopG Daro_0572 9 None None None 71908742 Common - hypothetical protein Daro_3129 12 None None None 71905747 Nonpathogen - hypothetical protein Daro_0105 10 None None None 71906571 Common - DNA repair protein RecN Daro_0932 196 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 71906085 Common - putative denitrification protein NorE Daro_0445 149 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 71909795 Common - hypothetical protein Daro_4186 16 None None None 71906743 Nonpathogen - hypothetical protein Daro_1104 2 COG1345 FliD, Flagellar capping protein Cell motility and secretion 71906044 Common - Amidohydrolase 2 Daro_0404 5 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 71909711 Common - hypothetical protein Daro_4102 12 None None None 71905843 Nonpathogen - ABC-type Mn2+/Zn2+ transport systems permease components-like protein Daro_0201 3 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 71909705 Common - Extracellular ligand-binding receptor Daro_4096 117 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 71909236 Common - fructose-1,6-bisphosphate aldolase Daro_3624 167 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 71906038 Common - hypothetical protein Daro_0397 2 None None None 71905806 Common - Conserved hypothetical protein 730 Daro_0164 139 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 71908422 Common - regulatory protein, LysR:LysR, substrate-binding Daro_2809 158 COG0583 LysR, Transcriptional regulator Transcription 71909465 Common - OmpA/MotB:Rickettsia 17 kDa surface antigen Daro_3854 167 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 71908287 Common rplT 50S ribosomal protein L20 Daro_2674 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 71907270 Nonpathogen - hypothetical protein Daro_1639 1 None None None 71909137 Common - C-5 cytosine-specific DNA methylase Daro_3525 97 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 71908439 Nonpathogen - hypothetical protein Daro_2826 1 None None None 71909758 Common - RNA polymerase factor sigma-54 Daro_4149 145 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 71908508 Common - Adenosylmethionine--8-amino-7-oxononanoate aminotransferase Daro_2895 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 71905887 Common - Outer membrane autotransporter barrel Daro_0245 17 None None None 71907259 Common - hypothetical protein Daro_1628 55 COG2862 COG2862, Predicted membrane protein Function unknown 71908825 Common - Manganese and iron superoxide dismutase Daro_3212 203 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 71906079 Common - hypothetical protein Daro_0439 6 None None None 71907885 Common - Heavy metal efflux pump CzcA Daro_2265 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 71907325 Common - Cobalt transport protein Daro_1695 13 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 71907356 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase Daro_1726 144 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 71909095 Common - Ribulose-phosphate 3-epimerase Daro_3483 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 71906219 Common - Dihydrofolate reductase region Daro_0579 143 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 71909003 Common - TRAP dicarboxylate transporter- DctP subunit Daro_3391 109 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 71906937 Common - Phage integrase Daro_1302 39 None None None 71905688 Common metH B12-dependent methionine synthase Daro_0046 178 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 71908971 Common - Forkhead-associated Daro_3359 45 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 71907413 Common - Molybdopterin binding domain Daro_1783 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 71909408 Common - Methane/phenol/toluene hydroxylase Daro_3796 16 None None None 71909503 Common - Holliday junction resolvase-like protein Daro_3892 181 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 71909730 Common - Protein of unknown function DUF224, cysteine-rich region:FAD linked oxidase, C-terminal:FAD linked oxidase, N-terminal Daro_4121 183 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 71908592 Common - GTP-binding protein, HSR1-related Daro_2979 216 COG2262 HflX, GTPases General function prediction only 71907343 Nonpathogen - hypothetical protein Daro_1713 1 None None None 71907051 Nonpathogen - hypothetical protein Daro_1419 7 None None None 71906203 Common - Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Daro_0563 228 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 71907738 Common - Glutamine amidotransferase class-I:Peptidase C26 Daro_2112 122 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 71907796 Common - Protein of unknown function DUF1316 Daro_2174 22 COG3518 COG3518, Uncharacterized protein conserved in bacteria Function unknown 71909316 Common - MltA:3D Daro_3704 93 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 71907576 Common - Serine O-acetyltransferase Daro_1947 210 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 71906244 Common - hypothetical protein Daro_0604 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 71907553 Nonpathogen - hypothetical protein Daro_1924 4 None None None 71907424 Common - CBS Daro_1794 133 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 71908350 Common - hypothetical protein Daro_2737 11 COG1694 MazG, Predicted pyrophosphatase General function prediction only 71908480 Common - malate dehydrogenase Daro_2867 78 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 71906014 Common - 3-hydroxybutyryl-CoA dehydrogenase Daro_0372 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 71909458 Nonpathogen - Protein of unknown function DUF1555 Daro_3847 1 None None None 71905754 Common - Rod shape-determining protein RodA Daro_0112 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 71908597 Common hisS histidyl-tRNA synthetase Daro_2984 248 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 71908493 Common - GGDEF Daro_2880 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 71906365 Common - CheW-like protein:ATP-binding region, ATPase-like:Signal transducing histidine kinase, homodimeric:Hpt Daro_0726 156 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 71908501 Common - NADH ubiquinone oxidoreductase, 20 kDa subunit Daro_2888 78 COG1740 HyaA, Ni,Fe-hydrogenase I small subunit Energy production and conversion 71909227 Nonpathogen - hypothetical protein Daro_3615 2 None None None 71907742 Common - Protein of unknown function DUF81 Daro_2116 51 COG0730 COG0730, Predicted permeases General function prediction only 71906061 Common - Protein of unknown function DUF161 Daro_0421 59 COG1284 COG1284, Uncharacterized conserved protein Function unknown 71906615 Common - hypothetical protein Daro_0976 4 COG5350 COG5350, Predicted protein tyrosine phosphatase General function prediction only 71908105 Common - Phosphate binding protein Daro_2488 179 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 71909031 Common - HAD-superfamily hydrolase subfamily IIIA:Phosphatase kdsC Daro_3419 106 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 71908371 Common - Glycosyl transferase, family 39 Daro_2758 65 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 71906793 Common - hypothetical protein Daro_1154 12 COG4398 COG4398, Uncharacterized protein conserved in bacteria Function unknown 71906115 Nonpathogen - hypothetical protein Daro_0475 1 None None None 71906053 Common - 4-hydroxybenzoate polyprenyl transferase, proteobacterial Daro_0413 159 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 71909531 Common - probable lipoprotein signal peptide Daro_3920 5 COG3678 CpxP, P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein Intracellular trafficking and secretion / Cell motility and secretio / Signal transduction mechanisms / Inorganic ion transport and metabolism 71907046 Common - Nitrogenase molybdenum-iron protein alpha chain:Nitrogenase component I, alpha chain Daro_1414 54 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 71906891 Common - hypothetical protein Daro_1253 22 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 71907611 Common - Ribosomal-protein-alanine acetyltransferase Daro_1982 190 COG0456 RimI, Acetyltransferases General function prediction only 71908121 Common - BRO family protein Daro_2504 32 COG3617 COG3617, Prophage antirepressor Transcription 71907018 Common - hypothetical protein Daro_1386 7 COG3678 CpxP, P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein Intracellular trafficking and secretion / Cell motility and secretio / Signal transduction mechanisms / Inorganic ion transport and metabolism 71907086 Common - Nitrogenase cofactor biosynthesis protein NifB Daro_1454 79 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 71907519 Common - Helix-turn-helix, AraC type:AraC-type transcriptional regulator, N-terminal Daro_1890 126 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 71909111 Common - Cell cycle protein Daro_3499 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 71908261 Common - plasmid-like conjugative transfer protein TraE Daro_2648 23 None None None 71906355 Common - Cytochrome c oxidase cbb3-type, subunit III Daro_0716 79 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 71907257 Nonpathogen - hypothetical protein Daro_1626 1 None None None 71905740 Common - Thiolase Daro_0098 184 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 71909770 Common - HAD-superfamily subfamily IIA hydrolase, hypothetical 2:HAD-superfamily hydrolase, subfamily IIA Daro_4161 85 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 71909511 Common - Phosphomethylpyrimidine kinase Daro_3900 219 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 71907234 Common - Protein kinase:GAF Daro_1602 171 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 71907183 Common - hypothetical protein Daro_1551 18 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 71906671 Nonpathogen - hypothetical protein Daro_1032 1 None None None 71906678 Nonpathogen - hypothetical protein Daro_1039 7 None None None 71907449 Common - Helicase, C-terminal:Type III restriction enzyme, res subunit:DEAD/DEAH box helicase, N-terminal Daro_1820 233 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 71906250 Common - regulatory protein, ArsR Daro_0610 171 COG0640 ArsR, Predicted transcriptional regulators Transcription 71906854 Common - Acyl-CoA dehydrogenase, C-terminal:Acyl-CoA dehydrogenase, central region Daro_1215 152 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 71906942 Common - Type I site-specific deoxyribonuclease HsdR Daro_1308 130 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 71909148 Common - D,D-heptose 1,7-bisphosphate phosphatase Daro_3536 126 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 71906961 Common - hypothetical protein Daro_1328 5 None None None 71909180 Common - ATP-binding region, ATPase-like:Histidine kinase A, N-terminal Daro_3568 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 71906418 Common - hypothetical protein Daro_0779 15 None None None 71909687 Common - Branched-chain amino acid aminotransferase I Daro_4078 217 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 71908429 Common - ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal Daro_2816 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71908686 Common - ketol-acid reductoisomerase Daro_3073 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 71908528 Nonpathogen - hypothetical protein Daro_2915 1 None None None 71906597 Common - NADH-ubiquinone/plastoquinone oxidoreductase, chain 6 Daro_0958 139 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 71905665 Common - heat shock protein HtpX Daro_0023 192 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 71907412 Common - Molybdopterin-guanine dinucleotide biosynthesis MobB region Daro_1782 117 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 71907757 Common - Protein of unknown function DUF1234 Daro_2133 52 COG3545 COG3545, Predicted esterase of the alpha/beta hydrolase fold General function prediction only 71907769 Common - Peptidase S41A, C-terminal protease Daro_2146 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 71909749 Common - Protein of unknown function DUF185 Daro_4140 92 COG1565 COG1565, Uncharacterized conserved protein Function unknown 71908487 Common - NnrS Daro_2874 56 COG3213 NnrS, Uncharacterized protein involved in response to NO Inorganic ion transport and metabolism 71909727 Common - Protein of unknown function DUF971 Daro_4118 52 COG3536 COG3536, Uncharacterized protein conserved in bacteria Function unknown 71908930 Common - Cobalamin adenosyltransferase Daro_3318 130 COG2096 COG2096, Uncharacterized conserved protein Function unknown 71909632 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Daro_4022 16 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 71905918 Common - Septum site-determining protein MinD Daro_0276 148 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 71907469 Common - hypothetical protein Daro_1840 9 None None None 71908765 Common - hypothetical protein Daro_3152 4 None None None 71908227 Common - putative efflux protein Daro_2614 22 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 71908813 Common - regulatory protein, LuxR Daro_3200 161 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 71909161 Common - PAS Daro_3549 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71907282 Common - hypothetical protein Daro_1651 10 None None None 71906065 Common groES co-chaperonin GroES Daro_0425 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 71908928 Common - FAD linked oxidase, C-terminal:FAD linked oxidase, N-terminal Daro_3315 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 71908255 Nonpathogen - hypothetical protein Daro_2642 1 None None None 71906623 Common - phosphoserine aminotransferase Daro_0984 104 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 71908026 Common - Glycosyl transferase, group 1 Daro_2407 221 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 71908461 Common - Lysyl-tRNA synthetase, class-2 Daro_2848 248 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 71908012 Nonpathogen - Protein of unknown function DUF1555 Daro_2393 1 None None None 71907777 Common - Heat shock protein DnaJ, N-terminal:Protein of unknown function DUF898, transmembrane bacterial Daro_2154 30 COG4269 COG4269, Predicted membrane protein Function unknown 71909023 Nonpathogen - hypothetical protein Daro_3411 2 None None None 71908833 Common - Lytic transglycosylase, catalytic Daro_3220 177 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 71906775 Common - regulatory protein, LysR:LysR, substrate-binding Daro_1136 181 COG0583 LysR, Transcriptional regulator Transcription 71909173 Common - hypothetical protein Daro_3561 11 None None None 71909484 Common - hypothetical protein Daro_3873 13 COG3287 COG3287, Uncharacterized conserved protein Function unknown 71905840 Common - hypothetical protein Daro_0198 17 None None None 71909425 Common - Membrane protein involved in aromatic hydrocarbon degradation Daro_3814 67 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 71909582 Common - predicted hydrogenase 2 cytochrome b type component Daro_3972 37 COG5557 COG5557, Polysulphide reductase Energy production and conversion 71907536 Common - DNA polymerase III, epsilon subunit Daro_1907 230 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 71908637 Common - NUDIX hydrolase Daro_3024 130 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 71907517 Nonpathogen - hypothetical protein Daro_1888 1 COG4987 CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 71908434 Common - YeeE/YedE Daro_2821 7 None None None 71906981 Common - Glycosyl hydrolase, BNR repeat Daro_1349 33 COG4447 COG4447, Uncharacterized protein related to plant photosystem II stability/assembly factor General function prediction only 71908703 Common moaC molybdenum cofactor biosynthesis protein C Daro_3090 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 71905927 Common - hypothetical protein Daro_0285 8 None None None 71907895 Nonpathogen - YHS Daro_2275 13 COG3350 COG3350, Uncharacterized conserved protein Function unknown 71907426 Common - Peptidase U32 Daro_1796 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 71908679 Common - Ribosomal protein S16 Daro_3066 211 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 71905716 Common - Allophanate hydrolase subunit 2 Daro_0074 230 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 71908574 Common - Peptidase M17, leucyl aminopeptidase, C-terminal Daro_2961 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 71908939 Common - Cytochrome c, class I Daro_3327 63 COG2863 COG2863, Cytochrome c553 Energy production and conversion 71909648 Common - Beta-lactamase-like Daro_4039 58 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 71907539 Nonpathogen - hypothetical protein Daro_1910 1 None None None 71908550 Nonpathogen - hypothetical protein Daro_2937 3 None None None 71909639 Common - TonB-dependent receptor Daro_4029 130 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 71908217 Common - Polysulphide reductase, NrfD Daro_2604 10 COG3301 NrfD, Formate-dependent nitrite reductase, membrane component Inorganic ion transport and metabolism 71907789 Nonpathogen - hypothetical protein Daro_2167 1 None None None 71908695 Common - Peptidase M17, leucyl aminopeptidase, C-terminal:Peptidase M17, leucyl aminopeptidase, N-terminal Daro_3082 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 71909477 Common argS arginyl-tRNA synthetase Daro_3866 245 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 71906664 Common - hypothetical protein Daro_1025 11 COG5501 COG5501, Predicted secreted protein Function unknown 71907498 Common - Protein of unknown function DUF808 Daro_1869 60 COG2354 COG2354, Uncharacterized protein conserved in bacteria Function unknown 71909620 Common actP acetate permease Daro_4010 179 COG4147 DhlC, Predicted symporter General function prediction only 71906382 Common - Sigma-70 region 4 Daro_0743 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 71907489 Nonpathogen - hypothetical protein Daro_1860 1 None None None 71907075 Common - Twin-arginine translocation pathway signal Daro_1443 116 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 71908295 Nonpathogen - hypothetical protein Daro_2682 1 None None None 71906378 Common flhB flagellar biosynthesis protein FlhB Daro_0739 129 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 71908360 Common - Conserved hypothetical protein ArsC related Daro_2747 107 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 71906583 Common - Peptidase M41, FtsH Daro_0944 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 71907102 Common - Cytochrome c oxidase, subunit I Daro_1470 174 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 71909335 Common - Coenzyme A biosynthesis protein:Cytidyltransferase-related Daro_3723 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 71906370 Common - CheD Daro_0731 86 COG1871 CheD, Chemotaxis protein; stimulates methylation of MCP proteins Cell motility and secretion / Signal transduction mechanisms 71907109 Common - Molybdenum-binding protein, N-terminal:Molybdenum-pterin binding protein Daro_1477 91 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 71908610 Common - Thioredoxin Daro_2997 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 71908290 Common - Threonyl-tRNA synthetase, class IIa Daro_2677 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 71908210 Common - Relaxase Daro_2597 22 None None None 71908502 Common - Nickel-dependent hydrogenase, large subunit Daro_2889 102 COG0374 HyaB, Ni,Fe-hydrogenase I large subunit Energy production and conversion 71908231 Common - hypothetical protein Daro_2618 22 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 71909060 Nonpathogen - hypothetical protein Daro_3448 3 None None None 71907967 Common - probable transmembrane protein Daro_2348 14 None None None 71907368 Common - 5'-methylthioadenosine phosphorylase Daro_1738 164 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 71908707 Common - ATP-dependent Clp protease adaptor protein ClpS Daro_3094 119 COG2127 COG2127, Uncharacterized conserved protein Function unknown 71906697 Common - BFD-like (2Fe-2S)-binding region Daro_1058 33 COG2906 Bfd, Bacterioferritin-associated ferredoxin Inorganic ion transport and metabolism 71908790 Common - sensory histidine kinase CreC Daro_3177 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71907249 Nonpathogen - hypothetical protein Daro_1618 1 None None None 71907381 Common - Outer membrane chaperone Skp (OmpH) Daro_1751 67 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 71906768 Common - ATP-dependent RNA helicase DbpA Daro_1129 238 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 71908347 Common - hypothetical protein Daro_2734 12 None None None 71906322 Common - probable Na+/H+ antiporter Daro_0683 40 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 71909104 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase Daro_3492 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 71908263 Common - TraB pilus assembly Daro_2650 26 None None None 71908185 Nonpathogen - hypothetical protein Daro_2569 2 None None None 71907977 Common - inner-membrane translocator Daro_2358 150 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 71908908 Common - hypothetical protein Daro_3295 28 COG4391 COG4391, Uncharacterized protein conserved in bacteria Function unknown 71906690 Common - ATPase, E1-E2 type:Copper-translocating P-type ATPase:Heavy metal translocating P-type ATPase Daro_1051 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 71907655 Common - Peptidase S26A, signal peptidase I Daro_2027 212 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 71908404 Common - Transglycosylase-associated protein Daro_2791 49 COG2261 COG2261, Predicted membrane protein Function unknown 71908004 Common - Rhomboid-like protein Daro_2385 51 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 71909401 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Daro_3789 41 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 71907358 Nonpathogen - hypothetical protein Daro_1728 1 None None None 71909751 Common - PAS Daro_4142 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71906635 Common - Hemerythrin HHE cation binding region Daro_0996 18 COG2461 COG2461, Uncharacterized conserved protein Function unknown 71908281 Nonpathogen - hypothetical protein Daro_2668 1 None None None 71908175 Common - hypothetical protein Daro_2559 37 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 71905682 Common - PAS Daro_0040 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71908710 Common - Histidine kinase, HAMP region:Bacterial chemotaxis sensory transducer Daro_3097 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 71908759 Common - Response regulator receiver:Transcriptional regulatory protein, C-terminal Daro_3146 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 71908242 Nonpathogen - hypothetical protein Daro_2629 1 None None None 71907451 Common - Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase A, N-terminal Daro_1822 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71908719 Common - LrgB-like protein Daro_3106 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 71905695 Common - Nitrogen regulatory protein P-II Daro_0053 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 71908396 Common - Molybdate ABC transporter, permease protein Daro_2783 197 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 71908166 Nonpathogen - hypothetical protein Daro_2550 3 None None None 71908989 Common - Phosphoribosyl-ATP pyrophosphohydrolase Daro_3377 181 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 71907567 Common - Deoxyguanosinetriphosphate triphosphohydrolase Daro_1938 159 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 71908922 Common - Response regulator receiver Daro_3309 209 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 71908624 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Daro_3011 42 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 71908841 Common - hypothetical protein Daro_3228 7 None None None 71907171 Nonpathogen - hypothetical protein Daro_1539 1 None None None 71907780 Common - Protein of unknown function DUF302 Daro_2157 12 COG3439 COG3439, Uncharacterized conserved protein Function unknown 71908464 Common - O-acetylhomoserine/O-acetylserine sulfhydrylase Daro_2851 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 71906956 Common - hypothetical protein Daro_1323 6 None None None 71905792 Common - hypothetical protein Daro_0150 3 None None None 71908746 Common - Cytochrome c, class I Daro_3133 43 COG4654 COG4654, Cytochrome c551/c552 Energy production and conversion 71909434 Nonpathogen - hypothetical protein Daro_3823 2 None None None 71908239 Common - Heavy metal efflux pump CzcA Daro_2626 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 71906100 Common - Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase A, N-terminal Daro_0460 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71906389 Common - Flagellar basal-body rod protein FlgC Daro_0750 126 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 71905764 Common pyrE orotate phosphoribosyltransferase Daro_0122 155 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 71906895 Common - NAD-dependent epimerase/dehydratase:Polysaccharide biosynthesis protein CapD Daro_1257 227 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 71907803 Common - hypothetical protein Daro_2181 43 COG3455 COG3455, Uncharacterized protein conserved in bacteria Function unknown 71906186 Common - UvrD/REP helicase Daro_0546 230 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 71907388 Common - hypothetical protein Daro_1758 113 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 71907675 Common - Transport-associated Daro_2047 48 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 71907440 Common - MOSC Daro_1811 26 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 71907927 Nonpathogen - hypothetical protein Daro_2308 2 None None None 71908327 Common - Lipolytic enzyme, G-D-S-L Daro_2714 106 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 71909680 Nonpathogen - hypothetical protein Daro_4071 1 None None None 71906758 Common - Protein of unknown function DUF455 Daro_1119 47 COG2833 COG2833, Uncharacterized protein conserved in bacteria Function unknown 71907111 Common - hypothetical protein Daro_1479 19 None None None 71909807 Common - hypothetical protein Daro_4198 6 None None None 71909673 Common - Protein of unknown function DUF6, transmembrane Daro_4064 56 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 71907311 Common - Inositol monophosphatase Daro_1681 213 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 71908648 Common rpsT 30S ribosomal protein S20 Daro_3035 195 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 71908852 Common - acetaldehyde dehydrogenase Daro_3239 37 COG4569 MhpF, Acetaldehyde dehydrogenase (acetylating) Secondary metabolites biosynthesis, transport, and catabolism 71906402 Common fliP flagellar biosynthesis protein FliP Daro_0763 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 71907458 Common - putative lipoprotein involved in nitrous oxide reduction Daro_1829 21 COG4314 NosL, Predicted lipoprotein involved in nitrous oxide reduction Energy production and conversion 71909200 Common - PAS:GGDEF Daro_3588 186 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 71905895 Common - putative branched-chain amino acid transport system substrate-binding protein Daro_0253 33 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 71907480 Common - ATPase, E1-E2 type Daro_1851 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 71908659 Common ileS isoleucyl-tRNA synthetase Daro_3046 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 71909527 Common - Protein of unknown function DUF214 Daro_3916 160 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 71906654 Common - Major facilitator superfamily MFS_1 Daro_1015 201 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 71906145 Common - PAS:GGDEF Daro_0505 194 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 71907598 Common - Radical SAM Daro_1969 94 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 71908249 Common - Arsenical-resistance protein ACR3 Daro_2636 140 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 161377476 Common - chemotaxis regulator CheZ Daro_0737 43 COG3143 CheZ, Chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 71908147 Common - Phage integrase, N-terminal SAM-like Daro_2531 13 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 71909652 Common - Extracellular ligand-binding receptor Daro_4043 135 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 71907319 Common - Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase Daro_1689 108 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 71906713 Common - NUDIX hydrolase Daro_1074 100 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 71909544 Common - Phospholipid/glycerol acyltransferase Daro_3933 125 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 71909362 Common - PAS:GGDEF Daro_3750 190 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 71909267 Nonpathogen - hypothetical protein Daro_3655 5 None None None 71908455 Common - hypothetical protein Daro_2842 6 None None None 71905939 Common - Nitrogen regulatory protein P-II Daro_0297 171 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 71906907 Nonpathogen - hypothetical protein Daro_1272 2 None None None 71908641 Common - nucleotide-binding protein Daro_3028 107 COG1666 COG1666, Uncharacterized protein conserved in bacteria Function unknown 71905955 Common - DNA-directed RNA polymerase subunit beta' Daro_0313 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 71907900 Nonpathogen - tetrahydromethanopterin S-methyltransferase subunit A Daro_2280 17 COG4063 MtrA, Tetrahydromethanopterin S-methyltransferase, subunit A Coenzyme metabolism 71905861 Nonpathogen - hypothetical protein Daro_0219 1 None None None 71909700 Common - Glycosyl hydrolase, BNR repeat Daro_4091 18 None None None 71909718 Common - ATP synthase F0, C subunit Daro_4109 63 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 71909049 Common - GCN5-related N-acetyltransferase Daro_3437 95 COG3153 COG3153, Predicted acetyltransferase General function prediction only 71907336 Common - NAD-dependent epimerase/dehydratase:3-beta hydroxysteroid dehydrogenase/isomerase:dTDP-4-dehydrorhamnose reductase Daro_1706 114 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 71909580 Common - Peptidase M52, hydrogen uptake protein:Peptidase M52, hydrogenase expression/formation protein:Peptidase M52, hydrogenase maturation peptidase Daro_3970 82 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 71908445 Common - ComEC/Rec2-related protein:DNA internalization-related competence protein ComEC/Rec2 Daro_2832 162 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 71906865 Common - 2-phosphoglycolate phosphatase, prokaryotic:HAD-superfamily hydrolase, subfamily IA, variant 1 Daro_1226 183 COG0546 Gph, Predicted phosphatases General function prediction only 71907520 Common - Ferredoxin:(2Fe-2S)-binding Daro_1891 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 71909040 Common - molecular chaperone-like protein Daro_3428 233 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 71906746 Common - hypothetical protein Daro_1107 16 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 71906603 Common - Ribonucleotide reductase large subunit Daro_0964 223 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 71905700 Common - GGDEF Daro_0058 181 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 71907616 Common - DNA repair protein RadA Daro_1987 203 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 71906390 Common - Flagellar hook capping protein Daro_0751 92 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 71905821 Common - Peptidase U32 Daro_0179 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 71908178 Common - hypothetical protein Daro_2562 6 None None None 71908065 Common - Zn-finger, prokaryotic DksA/TraR C4 type Daro_2447 161 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 71906334 Common - OmpA/MotB Daro_0695 149 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 71906786 Common - probable chemotaxis protein Daro_1147 87 COG1871 CheD, Chemotaxis protein; stimulates methylation of MCP proteins Cell motility and secretion / Signal transduction mechanisms 71909470 Common - probable cytochrome c5 Daro_3859 48 COG3245 CycB, Cytochrome c5 Energy production and conversion 71907473 Common - Electron transport protein SCO1/SenC Daro_1844 103 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 71909659 Common - Radical SAM Daro_4050 168 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 71907154 Common - Protein of unknown function DUF1348 Daro_1522 49 COG3558 COG3558, Uncharacterized protein conserved in bacteria Function unknown 71908180 Common - Protein of unknown function DUF1173 Daro_2564 16 None None None 71907338 Common - Short-chain dehydrogenase/reductase SDR Daro_1708 192 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 71906556 Common - ErfK/YbiS/YcfS/YnhG Daro_0917 25 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 71909343 Common - 50S ribosomal protein L25/general stress protein Ctc Daro_3731 188 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 71909603 Common - Cytochrome c-type biogenesis protein CcmC Daro_3993 115 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 71906555 Common - Peptidyl-prolyl cis-trans isomerase, cyclophilin type Daro_0916 197 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 71907060 Common - Urease, beta subunit Daro_1428 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 71906352 Common - Cytochrome c oxidase cbb3-type, subunit I Daro_0713 142 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 71908114 Common - chemotaxis sensory transducer Daro_2497 72 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 71906274 Common aspS aspartyl-tRNA synthetase Daro_0634 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 71907185 Common - AMP-dependent synthetase and ligase Daro_1553 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 71908581 Common - RarD protein Daro_2968 96 COG2962 RarD, Predicted permeases General function prediction only 71905899 Common - L-carnitine dehydratase/bile acid-inducible protein F Daro_0257 115 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 71907026 Common - NifZ Daro_1394 26 None None None 71905730 Common - hypothetical protein Daro_0088 4 None None None 71907544 Nonpathogen - hypothetical protein Daro_1915 1 None None None 71906910 Common - Asparagine synthase, glutamine-hydrolyzing Daro_1275 153 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 71908587 Common - Adenylosuccinate synthetase Daro_2974 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 71907706 Common - Forkhead-associated Daro_2079 15 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 71905997 Common - YjgF-like protein Daro_0355 182 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 71906005 Common - Alpha/beta hydrolase fold Daro_0363 125 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 71907838 Nonpathogen - hypothetical protein Daro_2216 2 None None None 71909525 Common - Protein of unknown function DUF81 Daro_3914 14 COG0730 COG0730, Predicted permeases General function prediction only 71908914 Nonpathogen - hypothetical protein Daro_3301 1 None None None 71909550 Common - Acetyl-CoA biotin carboxyl carrier Daro_3939 191 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 71907754 Common - transcriptional regulator CysB-like protein Daro_2129 191 COG0583 LysR, Transcriptional regulator Transcription 71908414 Common - Heavy metal efflux pump CzcA Daro_2801 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 71906819 Common - Response regulator receiver:Transcriptional regulatory protein, C-terminal Daro_1180 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 71906026 Common - regulatory proteins, IclR Daro_0384 91 COG1414 IclR, Transcriptional regulator Transcription 71906265 Common - GTP-binding Daro_0625 180 COG0218 COG0218, Predicted GTPase General function prediction only 71907067 Common - ABC transporter related Daro_1435 249 COG4674 COG4674, Uncharacterized ABC-type transport system, ATPase component General function prediction only 71907582 Common hscB co-chaperone HscB Daro_1953 55 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 71908618 Common - Response regulator receiver:Metal-dependent phosphohydrolase, HD subdomain Daro_3005 223 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 71905810 Common - putative transmembrane protein Daro_0168 21 None None None 71908875 Common - ABC transporter, transmembrane region:ABC transporter related Daro_3262 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 71906482 Common - HhH-GPD Daro_0843 114 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 71909249 Common - Ribulose bisphosphate carboxylase, large chain Daro_3637 67 COG1850 RbcL, Ribulose 1,5-bisphosphate carboxylase, large subunit Carbohydrate transport and metabolism 71907963 Nonpathogen - Hpt Daro_2344 1 None None None 71906882 Common - Aldo/keto reductase Daro_1244 27 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 71906913 Common - NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR:3-beta hydroxysteroid dehydrogenase/isomerase:Polysaccharide biosynthesis protein CapD:dTDP-4-dehydrorhamnose reductase Daro_1278 164 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 71906728 Common - Cyclic nucleotide-binding Daro_1089 88 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 71909596 Common - Peptidase M52, hydrogen uptake protein:Peptidase M52, hydrogenase expression/formation protein:Peptidase M52, hydrogenase maturation peptidase Daro_3986 70 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 71907032 Common - regulatory protein, LuxR:Response regulator receiver Daro_1400 221 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 71908974 Common - Integral membrane protein TerC Daro_3362 80 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 71909084 Common obgE GTPase ObgE Daro_3472 249 COG0536 Obg, Predicted GTPase General function prediction only 71907600 Common - Protein of unknown function DUF52 Daro_1971 69 COG1355 COG1355, Predicted dioxygenase General function prediction only 71909102 Common - hypothetical protein Daro_3490 13 COG4701 COG4701, Uncharacterized protein conserved in bacteria Function unknown 71906973 Common - Antibiotic biosynthesis monooxygenase Daro_1341 28 COG1359 COG1359, Uncharacterized conserved protein Function unknown 71908164 Nonpathogen - hypothetical protein Daro_2548 1 None None None 71906181 Nonpathogen - hypothetical protein Daro_0541 1 None None None 71908306 Nonpathogen - hypothetical protein Daro_2693 1 None None None 71908014 Common - Protein of unknown function DUF214 Daro_2395 107 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 71908386 Common - Hydratase/decarboxylase Daro_2773 60 COG3971 COG3971, 2-keto-4-pentenoate hydratase Secondary metabolites biosynthesis, transport, and catabolism 71906512 Common - Folylpolyglutamate synthetase Daro_0873 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 71907131 Common - NAD(P) transhydrogenase, beta subunit Daro_1499 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 71906509 Common - tryptophan synthase subunit beta Daro_0870 225 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 71907848 Nonpathogen - hypothetical protein Daro_2226 3 None None None 71909121 Common - putative thiol:disulphide interchange protein (periplasmic) Daro_3509 71 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 71909308 Common - Hemerythrin HHE cation binding region Daro_3696 44 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 71907138 Common - Dinitrogenase iron-molybdenum cofactor biosynthesis Daro_1506 34 COG1433 COG1433, Uncharacterized conserved protein Function unknown 71906419 Nonpathogen - hypothetical protein Daro_0780 1 None None None 71907516 Common - DNA-3-methyladenine glycosylase I Daro_1887 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 71907272 Common - hypothetical protein Daro_1641 7 None None None 71908157 Nonpathogen - hypothetical protein Daro_2541 5 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 71905841 Common - Periplasmic solute binding protein Daro_0199 117 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 71906025 Common - enoyl-CoA hydratase Daro_0383 176 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 71907151 Common - hypothetical protein Daro_1519 50 COG4117 COG4117, Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) Energy production and conversion 71905999 Common - regulatory protein, LysR:LysR, substrate-binding Daro_0357 190 COG0583 LysR, Transcriptional regulator Transcription 71909005 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Daro_3393 218 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 71905678 Common - MOSC Daro_0036 79 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 71908558 Common - Small GTP-binding protein domain:Sulfate adenylyltransferase, large subunit Daro_2945 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 71906676 Common - Phage integrase Daro_1037 114 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 71906080 Common - Dihydrolipoamide dehydrogenase Daro_0440 241 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 71908896 Common - Cytochrome c, class II Daro_3283 20 COG3909 COG3909, Cytochrome c556 Energy production and conversion 71909196 Common - N-acetylglutamate synthase Daro_3584 188 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 71905853 Common - Fimbrial assembly Daro_0211 45 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 71907976 Common - Extracellular ligand-binding receptor Daro_2357 107 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 71907778 Common - Peptidase M48, Ste24p Daro_2155 60 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 71909336 Common - 4Fe-4S ferredoxin, iron-sulfur binding Daro_3724 125 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 71905752 Common - Response regulator receiver Daro_0110 211 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 71906055 Common - Carboxylyase-related protein Daro_0415 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 71908673 Common - Polyprenyl synthetase Daro_3060 242 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 71906214 Common - Methionyl-tRNA synthetase, class Ia:Methionyl-tRNA synthetase, beta subunit, C-terminal Daro_0574 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 71907341 Common - Integrase, catalytic region Daro_1711 153 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 71909519 Common - TonB, C-terminal Daro_3908 32 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 71905694 Common - Conserved hypothetical protein 2001 Daro_0052 41 None None None 71908590 Common - HflC Daro_2977 215 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 71908353 Common - transferase hexapeptide repeat Daro_2740 201 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 71907236 Common - Pseudouridine synthase, RluD Daro_1604 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 71906523 Nonpathogen - Prokaryotic N-terminal methylation site Daro_0884 4 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 71907555 Common - hypothetical protein Daro_1926 10 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 71908267 Nonpathogen - hypothetical protein Daro_2654 3 None None None 71908326 Common - ABC transporter related Daro_2713 249 COG4181 COG4181, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 71908356 Common - flagellar assembly protein FliW Daro_2743 34 COG1699 COG1699, Uncharacterized protein conserved in bacteria Function unknown 71905722 Common - Binding-protein-dependent transport systems inner membrane component Daro_0080 179 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 71907607 Common - HDIG Daro_1978 62 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 71907558 Common - Rhodanese-like Daro_1929 14 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 71909224 Common - Conserved hypothetical phage tail region protein Daro_3612 25 None None None 71909037 Common - hypothetical protein Daro_3425 30 None None None 71906796 Common - Radical SAM Daro_1157 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 71908232 Nonpathogen - hypothetical protein Daro_2619 8 None None None 71908200 Common - ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal Daro_2586 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71908905 Common - hypothetical protein Daro_3292 3 None None None 71906353 Common - Cytochrome C oxidase, mono-heme subunit/FixO Daro_0714 82 COG2993 CcoO, Cbb3-type cytochrome oxidase, cytochrome c subunit Energy production and conversion 71905645 Common gyrB DNA gyrase subunit B Daro_0003 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 71906789 Common - hypothetical protein Daro_1150 2 None None None 71908331 Common - GCN5-related N-acetyltransferase:CoA-binding Daro_2718 157 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 71908606 Common - TRAP dicarboxylate transporter- DctP subunit Daro_2993 106 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 71905839 Nonpathogen - hypothetical protein Daro_0197 1 None None None 71906708 Common - Major facilitator superfamily MFS_1 Daro_1069 48 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 71908049 Common - esterase/lipase/thioesterase family active site Daro_2431 19 COG2267 PldB, Lysophospholipase Lipid metabolism 71907904 Common - Transposase IS3/IS911 Daro_2284 28 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 71907612 Common - Phage SPO1 DNA polymerase-related protein Daro_1983 158 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 71906337 Common - regulatory protein, ArsR Daro_0698 61 COG0640 ArsR, Predicted transcriptional regulators Transcription 71908994 Common - Imidazoleglycerol-phosphate dehydratase Daro_3382 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 71909456 Common - Guanylate kinase Daro_3845 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 71908753 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase Daro_3140 178 COG0756 Dut, dUTPase Nucleotide transport and metabolism 71907186 Common - 2-nitropropane dioxygenase, NPD Daro_1554 126 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 71909263 Common - hypothetical protein Daro_3651 2 None None None 71909530 Common - RND efflux system, outer membrane lipoprotein, NodT Daro_3919 111 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 71908050 Nonpathogen - hypothetical protein Daro_2432 5 None None None 71907220 Nonpathogen - hypothetical protein Daro_1588 1 None None None 71906435 Nonpathogen - hypothetical protein Daro_0796 2 None None None 71906050 Common - hypothetical protein Daro_0410 2 None None None 71906156 Common - hypothetical protein Daro_0516 58 COG3825 COG3825, Uncharacterized protein conserved in bacteria Function unknown 71906383 Common motC flagellar motor protein Daro_0744 117 COG1291 MotA, Flagellar motor component Cell motility and secretion 71908990 Common - Phosphoribosyl-AMP cyclohydrolase Daro_3378 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 71905933 Common - Peptidase S11, D-alanyl-D-alanine carboxypeptidase 1 Daro_0291 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 71908779 Nonpathogen - hypothetical protein Daro_3166 1 None None None 71906745 Common - hypothetical protein Daro_1106 4 None None None 71907896 Common - hypothetical protein Daro_2276 8 None None None 71908744 Common - hypothetical protein Daro_3131 32 None None None 71906360 Common - NUDIX hydrolase Daro_0721 92 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 71909753 Common - Forkhead-associated Daro_4144 30 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 71905759 Common - Glutamyl-tRNA(Gln) amidotransferase C subunit Daro_0117 144 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 71907942 Nonpathogen - hypothetical protein Daro_2323 3 None None None 71907008 Nonpathogen - hypothetical protein Daro_1376 1 None None None 71908409 Common - YceI Daro_2796 115 COG2353 COG2353, Uncharacterized conserved protein Function unknown 71906036 Common - Rhs element Vgr protein Daro_0394 57 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 71906999 Common - regulatory protein, LuxR Daro_1367 24 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 71905848 Common - RNA-binding S4 Daro_0206 115 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 71907329 Common - pyrroloquinoline quinone biosynthesis protein PqqB Daro_1699 36 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 71906637 Common - hypothetical protein Daro_0998 14 None None None 71908863 Common - Alpha/beta hydrolase fold Daro_3250 177 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 71908418 Common - hypothetical protein Daro_2805 23 None None None 71905873 Common clpX ATP-dependent protease ATP-binding subunit Daro_0231 218 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 71905970 Common - Ribosomal protein S17 Daro_0328 229 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 71907122 Common - SoxR-reducing system protein RsxE Daro_1490 76 COG4660 RnfE, Predicted NADH:ubiquinone oxidoreductase, subunit RnfE Energy production and conversion 71908847 Common - ABC transporter related Daro_3234 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 71908730 Common - hypothetical protein Daro_3117 11 None None None 71907322 Common - Cobalamin (vitamin B12) biosynthesis CbiX protein Daro_1692 60 COG2138 COG2138, Uncharacterized conserved protein Function unknown 71905919 Common - Septum formation topological specificity factor MinE Daro_0277 87 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 71909419 Common - 4-hydroxy-2-ketovalerate aldolase Daro_3808 208 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 71909697 Common - TonB-dependent receptor Daro_4088 78 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 71906655 Common - Penicillin-binding protein 1A Daro_1016 202 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 71909153 Common - hypothetical protein Daro_3541 16 None None None 71905837 Nonpathogen - hypothetical protein Daro_0195 1 None None None 71905884 Common - Helix-turn-helix, Fis-type Daro_0242 80 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 71906806 Common - ABC transporter related Daro_1167 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 71909079 Common - MaoC-like dehydratase Daro_3467 101 COG2030 MaoC, Acyl dehydratase Lipid metabolism 71908516 Common - intracellular septation protein A Daro_2903 76 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 71907372 Common rpsB 30S ribosomal protein S2 Daro_1742 222 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 71907129 Common - Alanine dehydrogenase/PNT, C-terminal:Alanine dehydrogenase/PNT, N-terminal Daro_1497 167 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 71907815 Common - Ankyrin Daro_2193 114 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 71909042 Common - hypothetical protein Daro_3430 13 None None None 71908197 Common - 4Fe-4S ferredoxin, iron-sulfur binding Daro_2583 146 COG1140 NarY, Nitrate reductase beta subunit Energy production and conversion 71905746 Common - Poly(R)-hydroxyalkanoic acid synthase, class I Daro_0104 69 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 71908053 Common - Orn/DAP/Arg decarboxylase 2 Daro_2435 218 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 71909793 Common - Extracellular ligand-binding receptor Daro_4184 135 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 71909517 Common mtgA monofunctional biosynthetic peptidoglycan transglycosylase Daro_3906 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 71908126 Nonpathogen - hypothetical protein Daro_2510 1 None None None 71908411 Common - Response regulator receiver Daro_2798 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 71909806 Common - Monooxygenase, FAD-binding:FAD dependent oxidoreductase:Tryptophan halogenase Daro_4197 113 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 71905956 Common rpsL 30S ribosomal protein S12 Daro_0314 235 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 71909483 Common - PAS Daro_3872 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71906343 Common - Response regulator receiver:Transcriptional regulatory protein, C-terminal Daro_0704 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 71906430 Nonpathogen - hypothetical protein Daro_0791 3 None None None 71908735 Common - Alanine dehydrogenase/PNT, C-terminal:Alanine dehydrogenase/PNT, N-terminal Daro_3122 167 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 71907574 Common - putative acyl-carrier-protein Daro_1945 45 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 71907206 Common - PAS Daro_1574 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71907432 Common - ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal Daro_1802 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71908103 Common - hypothetical protein Daro_2486 22 None None None 71909133 Common - BRO, N-terminal Daro_3521 38 COG3617 COG3617, Prophage antirepressor Transcription 71905782 Common cobD cobalamin biosynthesis protein Daro_0140 151 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 71908859 Common - ring hydroxylating dioxygenase, alpha subunit:Rieske (2Fe-2S) region Daro_3246 79 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 71907143 Nonpathogen - hypothetical protein Daro_1511 1 None None None 71909092 Common - Glycosyl transferase, family 2 Daro_3480 203 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 71909509 Common - Response regulator receiver Daro_3898 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 71907064 Common - hypothetical protein Daro_1432 25 COG2519 GCD14, tRNA(1-methyladenosine) methyltransferase and related methyltransferases Translation, ribosomal structure and biogenesis 71908079 Common - Sua5/YciO/YrdC/YwlC Daro_2461 214 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 71907025 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Daro_1393 98 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 71909400 Common - Protein of unknown function DUF336 Daro_3788 84 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 71908201 Common - PAS Daro_2587 83 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 71907438 Common - Glycine cleavage H-protein Daro_1809 149 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 71907541 Common - hypothetical protein Daro_1912 16 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 71906838 Nonpathogen - Ankyrin Daro_1199 14 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 71909299 Common prfA peptide chain release factor 1 Daro_3687 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 71907987 Common - 3-oxoacyl-(acyl carrier protein) synthase III Daro_2368 170 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 71909052 Nonpathogen - hypothetical protein Daro_3440 1 None None None 71906304 Common - phosphoenolpyruvate carboxykinase Daro_0665 59 COG1274 PckA, Phosphoenolpyruvate carboxykinase (GTP) Energy production and conversion 71907379 Common - Peptidase M50, putative membrane-associated zinc metallopeptidase Daro_1749 210 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 71905738 Common - Acyl-CoA dehydrogenase, C-terminal:Acyl-CoA dehydrogenase, central region:Acyl-CoA dehydrogenase, N-terminal Daro_0096 164 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 71906160 Common - Secreted repeat of unknown function Daro_0520 37 COG4315 COG4315, Uncharacterized protein conserved in bacteria Function unknown 71906201 Common - chemotaxis sensory transducer Daro_0561 139 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 71909445 Common - regulatory protein, LysR:LysR, substrate-binding Daro_3834 143 COG0583 LysR, Transcriptional regulator Transcription 71906016 Common - Phenylacetate-CoA ligase Daro_0374 117 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 71905932 Common - Aminotransferase, class IV Daro_0290 187 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 71909270 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Daro_3658 159 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 71909292 Common - Histidine kinase internal region Daro_3680 101 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 71906148 Common - probable putative transmembrane protein Daro_0508 14 None None None 71906257 Common - Phosphoribosyltransferase Daro_0617 178 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 71908274 Common - hypothetical protein Daro_2661 5 None None None 71908503 Common - Peptidase M52, hydrogen uptake protein Daro_2890 226 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71908082 Common - Glycine cleavage H-protein Daro_2464 185 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 71906540 Common - Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B Daro_0901 30 COG3384 COG3384, Uncharacterized conserved protein Function unknown 71906618 Common - NADH dehydrogenase (ubiquinone), 24 kDa subunit:Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit Daro_0979 167 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 71906132 Common - Cyclopropane-fatty-acyl-phospholipid synthase Daro_0492 125 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 71907853 Common - DNA repair protein RadC Daro_2231 164 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 71907044 Common - NifT/FixU Daro_1412 13 COG5554 NifU, Nitrogen fixation protein Secondary metabolites biosynthesis, transport, and catabolism 71907361 Common - Cytidine/deoxycytidylate deaminase, zinc-binding region Daro_1731 210 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 71909437 Common - Metallophosphoesterase Daro_3826 101 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 71906006 Common - ABC transporter related:Hemerythrin HHE cation binding region Daro_0364 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 71908385 Common - Extracellular ligand-binding receptor Daro_2772 127 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 71908663 Common - hypothetical protein Daro_3050 204 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 71907407 Common - fumarate reductase Daro_1777 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 71908133 Common - ATPase associated with various cellular activities, AAA_3:ATPase associated with various cellular activities, AAA_5 Daro_2517 176 COG0714 COG0714, MoxR-like ATPases General function prediction only 71906547 Common - inner-membrane translocator:ABC transporter related Daro_0908 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 71909253 Common - hypothetical protein Daro_3641 3 None None None 71909490 Common - UvrD/REP helicase Daro_3879 231 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 71909451 Nonpathogen - hypothetical protein Daro_3840 1 None None None 71906109 Common - extracellular solute-binding protein, family 3 Daro_0469 74 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 71908188 Common - hypothetical protein Daro_2572 3 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 71906236 Common - hypothetical protein Daro_0596 60 COG3028 COG3028, Uncharacterized protein conserved in bacteria Function unknown 71909622 Common - Enoyl-CoA hydratase/isomerase Daro_4012 178 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 71906488 Nonpathogen - hypothetical protein Daro_0849 1 None None None 71907053 Common - Rieske (2Fe-2S) region Daro_1421 21 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 71907562 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Daro_1933 163 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 71906297 Common - Polyprenyl synthetase Daro_0658 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 71909665 Common - MotA/TolQ/ExbB proton channel Daro_4056 150 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 71908889 Nonpathogen - hypothetical protein Daro_3276 1 None None None 71909114 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase Daro_3502 204 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 71909377 Common - Rhodanese-like Daro_3765 43 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 71905816 Common - Amino acid adenylation Daro_0174 223 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 71908089 Nonpathogen - hypothetical protein Daro_2471 1 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 71907173 Common - Dihydrofolate reductase region Daro_1541 143 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 71907265 Common - Protein of unknown function DUF294, nucleotidyltransferase putative Daro_1634 64 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 71908093 Common - hypothetical protein Daro_2475 12 None None None 71908142 Common - Phage integrase Daro_2526 102 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 71908954 Common - hypothetical protein Daro_3342 42 None None None 71907639 Common - Maf-like protein Daro_2011 192 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 71907996 Common - Histone deacetylase superfamily Daro_2377 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 71908279 Common - Filamentation induced by cAMP protein Fic Daro_2666 49 COG3177 COG3177, Uncharacterized conserved protein Function unknown 71907732 Common - Filamentous haemagglutinin, N-terminal Daro_2106 90 None None None 71906245 Common - Riboflavin biosynthesis protein RibD:Riboflavin-specific deaminase, C-terminal Daro_0605 229 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 71909012 Common - Mammalian cell entry related Daro_3400 90 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 71908789 Common - DNA-binding response regulator CreB Daro_3176 218 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 71907634 Common - Ribonuclease E and G Daro_2005 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 71908860 Common - Rieske (2Fe-2S) region Daro_3247 60 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 71906492 Common - Patatin Daro_0853 63 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 71907959 Common - hypothetical protein Daro_2340 67 COG2914 COG2914, Uncharacterized protein conserved in bacteria Function unknown 71908784 Common - tRNA isopentenyltransferase Daro_3171 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 71907696 Common - 6-phosphogluconate dehydrogenase Daro_2069 179 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 71906901 Common - NAD-dependent epimerase/dehydratase:dTDP-4-dehydrorhamnose reductase Daro_1263 140 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 71907094 Common - Cytochrome oxidase assembly Daro_1462 47 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 71908573 Common - Response regulator receiver Daro_2960 222 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 71907720 Common - GAF:ATP-binding region, ATPase-like:Histidine kinase internal region:5TM Receptors of the LytS-YhcK type, transmembrane region Daro_2094 105 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 71907719 Common - putative two-component response-regulatory protein YehT Daro_2093 205 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 71906131 Common - Protein of unknown function DUF1365 Daro_0491 63 COG3496 COG3496, Uncharacterized conserved protein Function unknown 71906922 Common cysM cysteine synthase B Daro_1287 221 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 71907939 Common - hypothetical protein Daro_2320 43 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 71907950 Common - hypothetical protein Daro_2331 22 None None None 71909279 Common - AICARFT/IMPCHase bienzyme Daro_3667 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 71906155 Nonpathogen - hypothetical protein Daro_0515 1 None None None 71906047 Common - Prolipoprotein diacylglyceryl transferase Daro_0407 30 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 71906665 Common - Beta-lactamase-like Daro_1026 100 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 71908207 Common - hypothetical protein Daro_2593 4 None None None 71909324 Common - hypothetical protein Daro_3712 15 None None None 71909373 Common - Acriflavin resistance protein Daro_3761 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 71907750 Common - hypothetical protein Daro_2125 12 COG1633 COG1633, Uncharacterized conserved protein Function unknown 71906426 Common - GGDEF Daro_0787 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 71909574 Nonpathogen - hypothetical protein Daro_3964 1 None None None 71908760 Common - ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal Daro_3147 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71908491 Common - Beta-lactamase-like Daro_2878 83 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 71907601 Common - MgtC/SapB transporter Daro_1972 65 COG3174 COG3174, Predicted membrane protein Function unknown 71908378 Common - Extracellular ligand-binding receptor Daro_2765 104 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 71907145 Common - HesB/YadR/YfhF Daro_1513 165 COG0316 IscA, Uncharacterized conserved protein Function unknown 71905731 Common - Biotin/lipoyl attachment:Carbamoyl-phosphate synthase L chain, ATP-binding:Carbamoyl-phosphate synthetase large chain, N-terminal:Biotin carboxylase, C-terminal Daro_0089 231 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 71907295 Nonpathogen - hypothetical protein Daro_1664 1 None None None 71905941 Nonpathogen - hypothetical protein Daro_0299 1 None None None 71905948 Common secE preprotein translocase subunit SecE Daro_0306 28 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 71906057 Common - Radical SAM Daro_0417 76 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 71906066 Common groEL chaperonin GroEL Daro_0426 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 71909302 Common - Sulphate transport system permease protein 1 Daro_3690 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 71906423 Common - Flagellin, C-terminal:Flagellin, N-terminal Daro_0784 125 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 71908950 Common - YcgR Daro_3338 21 COG5581 COG5581, Predicted glycosyltransferase Cell envelope biogenesis, outer membrane 71906473 Common - regulatory protein, LuxR:Response regulator receiver Daro_0834 224 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 71909779 Common - Beta-ketoacyl synthase Daro_4170 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 71907874 Common - Outer membrane efflux protein Daro_2254 54 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 71906534 Common - TPR repeat Daro_0895 34 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 71906878 Common - dTDP-4-dehydrorhamnose 3,5-epimerase related Daro_1239 167 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 71906138 Common - TrkA-N Daro_0498 73 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 71907640 Common - Protein of unknown function DUF177 Daro_2012 36 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 71909204 Common - Glyceraldehyde-3-phosphate dehydrogenase, type I Daro_3592 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 71906481 Common - putative signal transduction protein containing EAL and modified HD-GYP domains Daro_0842 39 COG3434 COG3434, Predicted signal transduction protein containing EAL and modified HD-GYP domains Signal transduction mechanisms 71908840 Common - probable proline-rich transmembrane protein Daro_3227 5 None None None 71906490 Common rumA 23S rRNA (uracil-5-)-methyltransferase Daro_0851 200 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 71907581 Common - HesB/YadR/YfhF:Iron-sulphur cluster assembly protein IscA Daro_1952 164 COG0316 IscA, Uncharacterized conserved protein Function unknown 71906188 Common - Zinc-containing alcohol dehydrogenase superfamily Daro_0548 188 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 71909372 Common - Secretion protein HlyD Daro_3760 163 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 71906595 Common - Respiratory-chain NADH dehydrogenase, subunit 1 Daro_0956 186 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 71907645 Common - 3-oxoacyl-(acyl-carrier-protein) reductase Daro_2017 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 71907471 Common - Protein of unknown function DUF214 Daro_1842 31 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 71909355 Common - PAS:GGDEF Daro_3743 220 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 71905656 Common - hypothetical protein Daro_0014 8 None None None 71906268 Common - HAD-superfamily hydrolase subfamily IA, variant 3:Pyrimidine 5-nucleotidase Daro_0628 51 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 71906979 Common - hypothetical protein Daro_1347 15 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 71908032 Common - Glycosyl transferase, family 2:Polysaccharide deacetylase Daro_2413 211 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 71906077 Common - Protein phosphatase 2C-like Daro_0437 139 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 71908027 Common - Asparagine synthase, glutamine-hydrolyzing Daro_2408 172 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 71908948 Common - Class II aldolase/adducin, N-terminal Daro_3336 141 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 71908976 Common sucC succinyl-CoA synthetase subunit beta Daro_3364 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 71908349 Common - Protein of unknown function DUF519 Daro_2736 85 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 71909611 Nonpathogen - hypothetical protein Daro_4001 1 None None None 71906299 Common - hypothetical protein Daro_0660 16 None None None 71907219 Common - Cytochrome c, class I Daro_1587 58 COG2863 COG2863, Cytochrome c553 Energy production and conversion 71905897 Common - putative phenylacetate-CoA ligase Daro_0255 99 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 71907546 Nonpathogen - hypothetical protein Daro_1917 1 None None None 71908873 Common - Cytochrome d1, heme region Daro_3260 20 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 71909657 Common - PAS:GGDEF Daro_4048 195 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 71907523 Common - hypothetical protein Daro_1894 53 COG2068 COG2068, Uncharacterized MobA-related protein General function prediction only 71909471 Common - Conserved hypothetical protein 91 Daro_3860 175 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 71907447 Common - Formate dehydrogenase, alpha subunit, anaerobic Daro_1818 180 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 71907247 Common - naphthoate synthase Daro_1616 179 COG0447 MenB, Dihydroxynaphthoic acid synthase Coenzyme metabolism 71906994 Common - PAS:GGDEF Daro_1362 193 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 71907843 Common - Helicase, C-terminal Daro_2221 48 COG4646 COG4646, DNA methylase Transcription / DNA replication, recombination, and repair 71908441 Common - Protein of unknown function DUF6, transmembrane Daro_2828 147 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 71907787 Common - hypothetical protein Daro_2165 22 COG3673 COG3673, Uncharacterized conserved protein Function unknown 71906183 Common - Rare lipoprotein B Daro_0543 29 COG2980 RlpB, Rare lipoprotein B Cell envelope biogenesis, outer membrane 71908402 Common - TonB-dependent receptor Daro_2789 115 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 71908068 Common - tRNA pseudouridine synthase B Daro_2450 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 71908656 Common - LytB protein Daro_3043 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 71909367 Common - Metal-dependent phosphohydrolase, HD subdomain Daro_3755 124 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 71906518 Common - type II secretion system protein E:General secretory system II, protein E, N-terminal Daro_0879 224 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 71907602 Common - 4-diphosphocytidyl-2C-methyl-D-erythritol synthase Daro_1973 196 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 71908173 Nonpathogen - hypothetical protein Daro_2557 4 None None None 71905950 Common rplK 50S ribosomal protein L11 Daro_0308 247 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 71907821 Common - Glycine cleavage T protein (aminomethyl transferase) Daro_2199 147 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 71906841 Common - Zinc-containing alcohol dehydrogenase superfamily Daro_1202 161 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 71906657 Common - Hydantoinase/oxoprolinase:Hydantoinaseoxoprolinase, N-terminal Daro_1018 104 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 71909523 Common - hypothetical protein Daro_3912 37 None None None 71907726 Common - Formate/nitrite transporter Daro_2100 89 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 71909238 Common - transketolase Daro_3626 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 71906392 Common - Protein of unknown function DUF1078 Daro_0753 123 COG4787 FlgF, Flagellar basal body rod protein Cell motility and secretion 71907911 Common - hypothetical protein Daro_2291 47 COG4643 COG4643, Uncharacterized protein conserved in bacteria Function unknown 71905811 Common - Cytidyltransferase-related:Probable nicotinate-nucleotide adenylyltransferase Daro_0169 184 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 71907353 Common - N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase Daro_1723 221 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 71905650 Common - PAS Daro_0008 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71906949 Nonpathogen - hypothetical protein Daro_1316 1 None None None 71907416 Nonpathogen - hypothetical protein Daro_1786 1 None None None 71908987 Common tatA twin argininte translocase protein A Daro_3375 87 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 71906409 Common - ATPase FliI/YscN Daro_0770 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 71906590 Common - NADH dehydrogenase subunit C Daro_0951 162 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 71906557 Common - TPR repeat Daro_0918 64 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 71907569 Common - hypothetical protein Daro_1940 26 COG4544 COG4544, Uncharacterized conserved protein Function unknown 71907479 Common - DNA topoisomerase IV subunit A Daro_1850 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 71905659 Common - regulatory protein, LysR:LysR, substrate-binding Daro_0017 187 COG0583 LysR, Transcriptional regulator Transcription 71909590 Nonpathogen - hypothetical protein Daro_3980 5 COG0374 HyaB, Ni,Fe-hydrogenase I large subunit Energy production and conversion 71906938 Common - N-6 DNA methylase Daro_1303 158 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 71909123 Nonpathogen - hypothetical protein Daro_3511 2 None None None 71905907 Common - ATP-binding region, ATPase-like:Histidine kinase A, N-terminal Daro_0265 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71905715 Common - hypothetical protein Daro_0073 53 COG3665 COG3665, Uncharacterized conserved protein Function unknown 71906457 Nonpathogen - hypothetical protein Daro_0818 1 None None None 71908535 Nonpathogen - hypothetical protein Daro_2922 14 COG0730 COG0730, Predicted permeases General function prediction only 71907037 Common - TPR repeat Daro_1405 75 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 71906813 Common - hypothetical protein Daro_1174 24 COG1647 COG1647, Esterase/lipase General function prediction only 71908724 Common - TonB, C-terminal Daro_3111 10 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 71909069 Common - hypothetical protein Daro_3457 11 None None None 71908168 Nonpathogen - hypothetical protein Daro_2552 3 None None None 71907495 Common - Protein of unknown function RIO1 Daro_1866 66 COG1718 RIO1, Serine/threonine protein kinase involved in cell cycle control Signal transduction mechanisms / Cell division and chromosome partitioning 71907808 Common - OmpA/MotB Daro_2186 165 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 71907760 Nonpathogen - hypothetical protein Daro_2136 1 None None None 71909038 Common - ATP-dependent helicase HrpA Daro_3426 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 71907526 Common - Metal-dependent phosphohydrolase, HD subdomain:CHASE2 Daro_1897 129 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 71906912 Common - sugar transferase Daro_1277 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 71906224 Common - Glycoside hydrolase, family 57 Daro_0584 35 COG1449 COG1449, Alpha-amylase/alpha-mannosidase Carbohydrate transport and metabolism 71907061 Common - Urease, gamma subunit region Daro_1429 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 71906931 Common - Outer membrane lipoprotein carrier protein LolA Daro_1296 91 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 71909086 Common - Porin, Gram-negative type Daro_3474 30 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 71906773 Common - hypothetical protein Daro_1134 38 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 71908515 Common - Response regulator receiver:Metal-dependent phosphohydrolase, HD subdomain Daro_2902 219 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 71909077 Nonpathogen - hypothetical protein Daro_3465 5 None None None 71906194 Common - Flavodoxin/nitric oxide synthase Daro_0554 80 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 71907529 Common - Peptidase S1C, Do Daro_1900 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 71905784 Nonpathogen - hypothetical protein Daro_0142 5 None None None 71908824 Common - Exonuclease VII, large subunit Daro_3211 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 71906096 Common - hypothetical protein Daro_0456 35 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 71908016 Common - Polysaccharide export protein Daro_2397 103 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 71906000 Common - Protein of unknown function DUF1228:Major facilitator superfamily MFS_1 Daro_0358 66 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 71907163 Nonpathogen - hypothetical protein Daro_1531 1 None None None 71908309 Nonpathogen - Protein of unknown function DUF1376 Daro_2696 2 COG3756 COG3756, Uncharacterized protein conserved in bacteria Function unknown 71908850 Common - Ferredoxin:Oxidoreductase FAD/NAD(P)-binding:Oxidoreductase FAD-binding region Daro_3237 151 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 71908857 Common - 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase Daro_3244 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 71907333 Common - Conserved hypothetical protein 374 Daro_1703 17 COG0392 COG0392, Predicted integral membrane protein Function unknown 71909309 Nonpathogen - hypothetical protein Daro_3697 1 None None None 71907730 Common - hypothetical protein Daro_2104 9 None None None 71906604 Common - PAS:Hemerythrin HHE cation binding region Daro_0965 219 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 71906344 Common - ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal Daro_0705 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71906650 Common - hypothetical protein Daro_1011 10 None None None 71905862 Common - UDP-N-acetylglucosamine pyrophosphorylase Daro_0220 231 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 71907455 Common - Phosphonate-binding periplasmic protein Daro_1826 98 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 71907810 Common - ImcF-related:Protein of unknown function DUF1215 Daro_2188 48 COG3523 IcmF, Uncharacterized protein conserved in bacteria Function unknown 71908220 Nonpathogen - hypothetical protein Daro_2607 2 None None None 71909712 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA Daro_4103 192 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 71907273 Nonpathogen - hypothetical protein Daro_1642 1 None None None 71906573 Common - Ferric-uptake regulator Daro_0934 196 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 71909556 Common - High-affinity nickel-transporter Daro_3945 40 COG3376 HoxN, High-affinity nickel permease Inorganic ion transport and metabolism 71909284 Common - Protein of unknown function DUF513, hemX Daro_3672 54 COG2959 HemX, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 71908443 Common - Alpha/beta hydrolase fold Daro_2830 87 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 71907240 Common - Poly(R)-hydroxyalkanoic acid synthase, class I Daro_1608 75 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 71906504 Common - aspartate-semialdehyde dehydrogenase Daro_0865 196 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 71908917 Nonpathogen - hypothetical protein Daro_3304 12 None None None 71909479 Common - GGDEF Daro_3868 179 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 71907115 Common - flavodoxin FldA Daro_1483 72 COG0716 FldA, Flavodoxins Energy production and conversion 71909360 Common - Succinic semialdehyde dehydrogenase Daro_3748 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 71909010 Common - Toluene tolerance Daro_3398 88 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 71909009 Common - NTP binding protein (contains STAS domain) Daro_3397 9 COG3113 COG3113, Predicted NTP binding protein (contains STAS domain) General function prediction only 71905807 Common - hypothetical protein Daro_0165 16 None None None 71906846 Common - ABC transporter related Daro_1207 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 71909681 Common - hypothetical protein Daro_4072 5 None None None 71909019 Common - type II secretion system protein E:General secretory system II, protein E, N-terminal Daro_3407 212 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 71905705 Common - Metal-dependent phosphohydrolase, HD subdomain Daro_0063 124 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 71906940 Common - Transposase IS3/IS911 Daro_1306 28 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 71909201 Common - Inositol phosphatase/fructose-1,6-bisphosphatase Daro_3589 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 71907682 Nonpathogen - hypothetical protein Daro_2054 8 COG3115 ZipA, Cell division protein Cell division and chromosome partitioning 71905866 Common - Response regulator receiver:Transcriptional regulatory protein, C-terminal Daro_0224 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 71906643 Common - Cytochrome B561, bacterial Daro_1004 75 COG3038 CybB, Cytochrome B561 Energy production and conversion 71907073 Common - PAS Daro_1441 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71908498 Common - Putative methyltransferase Daro_2885 31 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 71908643 Common - hypothetical protein Daro_3030 11 None None None 71906124 Common - Metal-dependent phosphohydrolase, HD subdomain Daro_0484 46 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 71907113 Nonpathogen - hypothetical protein Daro_1481 3 None None None 71909106 Common - Cell division protein FtsA Daro_3494 202 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 71909439 Common - Hydrophobe/amphiphile efflux-1 HAE1 Daro_3828 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 71909485 Common - CinA, C-terminal Daro_3874 190 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 71906794 Common - Endonuclease III/Nth Daro_1155 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 71909172 Common - ribose-5-phosphate isomerase A Daro_3560 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 71906917 Common - hypothetical protein Daro_1282 17 COG5416 COG5416, Uncharacterized integral membrane protein Function unknown 71906784 Common - CheD Daro_1145 87 COG1871 CheD, Chemotaxis protein; stimulates methylation of MCP proteins Cell motility and secretion / Signal transduction mechanisms 71908565 Common - TonB-dependent receptor Daro_2952 116 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 71909732 Common - threonine dehydratase Daro_4123 214 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 71907363 Common - probable ZipA related protein, possibly involved in cell division Daro_1733 24 COG3115 ZipA, Cell division protein Cell division and chromosome partitioning 71906276 Common - hypothetical protein Daro_0636 72 COG2331 COG2331, Uncharacterized protein conserved in bacteria Function unknown 71906897 Common - NAD-dependent epimerase/dehydratase:3-beta hydroxysteroid dehydrogenase/isomerase Daro_1259 41 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 71909710 Common - Response regulator receiver:Tetratricopeptide TPR_4 Daro_4101 132 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 71909625 Common - Triphosphoribosyl-dephospho-CoA protein Daro_4015 48 COG1767 CitG, Triphosphoribosyl-dephospho-CoA synthetase Coenzyme metabolism 71907610 Common - Peptidase M22, glycoprotease Daro_1981 140 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 71909801 Common - CBS:HPP Daro_4192 83 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 71908214 Common - ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal Daro_2601 204 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71907158 Common - Zinc-containing alcohol dehydrogenase superfamily Daro_1526 101 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 71907383 Common - Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ Daro_1753 187 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 71906989 Common - Short-chain dehydrogenase/reductase SDR Daro_1357 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 71909341 Common - 4-diphosphocytidyl-2C-methyl-D-erythritol kinase Daro_3729 192 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 71909432 Common - Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal Daro_3821 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71906110 Common - GGDEF Daro_0470 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 71908629 Common - FAD dependent oxidoreductase Daro_3016 82 COG2509 COG2509, Uncharacterized FAD-dependent dehydrogenases General function prediction only 71906364 Common - Response regulator receiver Daro_0725 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 71906630 Common - UspA Daro_0991 118 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 71906043 Nonpathogen - hypothetical protein Daro_0403 1 None None None 71906462 Common - Plasmid stabilization system Daro_0823 18 COG3668 ParE, Plasmid stabilization system protein General function prediction only 71908748 Common - regulatory protein, ArsR Daro_3135 140 COG0640 ArsR, Predicted transcriptional regulators Transcription 71907836 Common - hypothetical protein Daro_2214 3 None None None 71907392 Common - L-lactate permease Daro_1762 103 COG1620 LldP, L-lactate permease Energy production and conversion 71906102 Common - surface antigen (D15) Daro_0462 123 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 71909143 Common - Apolipoprotein N-acyltransferase Daro_3531 164 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 71905773 Nonpathogen - hypothetical protein Daro_0131 1 None None None 71909141 Common - hypothetical protein Daro_3529 206 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 71906179 Common - Acyl-CoA dehydrogenase, C-terminal:Acyl-CoA dehydrogenase, central region:Acyl-CoA dehydrogenase, N-terminal Daro_0539 161 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 71905797 Common - Glycosyl transferase, group 1 Daro_0155 226 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 71909496 Common - pyrroline-5-carboxylate reductase Daro_3885 211 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 71906252 Common - Glutaredoxin, GrxC Daro_0612 116 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 71906338 Common - Low molecular weight phosphotyrosine protein phosphatase Daro_0699 119 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 71906963 Common - Alpha/beta hydrolase fold Daro_1331 178 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 71906767 Nonpathogen - hypothetical protein Daro_1128 2 None None None 71908084 Common - hypothetical protein Daro_2466 15 None None None 71907968 Common - Peptidylprolyl isomerase, FKBP-type Daro_2349 116 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 71908431 Common - Protein of unknown function DUF894, DitE:Major facilitator superfamily MFS_1 Daro_2818 114 None None None 71905673 Common - Helix-turn-helix, Fis-type Daro_0031 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 71907794 Common - Protein of unknown function DUF1305 Daro_2172 45 COG3520 COG3520, Uncharacterized protein conserved in bacteria Function unknown 71908626 Common - hypothetical protein Daro_3013 9 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 71909185 Nonpathogen - GCN5-related N-acetyltransferase Daro_3573 1 COG3153 COG3153, Predicted acetyltransferase General function prediction only 71907673 Common - CheB methylesterase:MCP methyltransferase, CheR-type Daro_2045 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 71906331 Common - Cytochrome c, class I Daro_0692 26 COG4654 COG4654, Cytochrome c551/c552 Energy production and conversion 71906667 Common - TonB-dependent receptor Daro_1028 80 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 71908262 Common - hypothetical protein Daro_2649 8 None None None 161377478 Common - DNA topoisomerase III Daro_0018 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 71908398 Common - TonB-dependent receptor Daro_2785 118 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 71908413 Common - Secretion protein HlyD Daro_2800 86 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 71907981 Common - Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Daro_2362 226 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 71905981 Common secY preprotein translocase subunit SecY Daro_0339 222 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 71909339 Common - TPR repeat:Tetratricopeptide TPR_4 Daro_3727 127 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 71908450 Common - hypothetical protein Daro_2837 31 COG4255 COG4255, Uncharacterized protein conserved in bacteria Function unknown 71908705 Common - hypothetical protein Daro_3092 35 None None None 71908005 Common - homoserine dehydrogenase Daro_2386 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 71907894 Common - Metal-dependent phosphohydrolase, HD subdomain Daro_2274 124 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 71906686 Common - Cyclic nucleotide-binding:Bacterial regulatory protein, Crp Daro_1047 147 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 71908732 Common - Isocitrate dehydrogenase NADP-dependent, prokaryotic Daro_3119 222 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 71906889 Nonpathogen - Polysaccharide biosynthesis protein Daro_1251 7 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 71907801 Common - putative lipoprotein Daro_2179 10 COG3521 COG3521, Uncharacterized protein conserved in bacteria Function unknown 71908899 Common - hypothetical protein Daro_3286 15 COG4390 COG4390, Uncharacterized protein conserved in bacteria Function unknown 71908192 Nonpathogen - hypothetical protein Daro_2578 7 None None None 71905943 Common - Prolipoprotein diacylglyceryl transferase Daro_0301 209 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 71906928 Common - Thioredoxin reductase Daro_1293 248 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 71908716 Common - hypothetical protein Daro_3103 23 None None None 71908631 Common - hypothetical protein Daro_3018 134 COG2081 COG2081, Predicted flavoproteins General function prediction only 71906404 Common - Type III secretion system outer membrane O protein Daro_0765 122 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 71909212 Nonpathogen - TIR Daro_3600 2 None None None 71906068 Common - Na+/solute symporter Daro_0428 164 COG4147 DhlC, Predicted symporter General function prediction only 71906625 Common - Secretion protein HlyD Daro_0986 84 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 71906921 Common - ADP-L-glycero-D-manno-heptose-6-epimerase Daro_1286 210 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 71908362 Common - ATP-binding region, ATPase-like:Histidine kinase A, N-terminal Daro_2749 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71908007 Common - Protein of unknown function DUF598 Daro_2388 39 COG3737 COG3737, Uncharacterized conserved protein Function unknown 71906294 Common - Beta-lactamase-like Daro_0655 59 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 71906117 Common - Helix-turn-helix, Fis-type Daro_0477 219 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 71908546 Common - Histidine kinase, HAMP region:Bacterial chemotaxis sensory transducer Daro_2933 141 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 71907767 Common - possible predicted diverged CheY-domain Daro_2144 14 COG4378 COG4378, Uncharacterized protein conserved in bacteria Function unknown 71908835 Common - type II secretion system protein Daro_3222 138 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 71909112 Common - UDP-N-acetylmuramoylalanine-D-glutamate ligase Daro_3500 208 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 71908288 Common rpmI 50S ribosomal protein L35 Daro_2675 182 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 71907423 Common - OmpA/MotB Daro_1793 32 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 71909750 Common - hypothetical protein Daro_4141 48 COG3287 COG3287, Uncharacterized conserved protein Function unknown 71908380 Common - Hemerythrin HHE cation binding region Daro_2767 16 COG3945 COG3945, Uncharacterized conserved protein Function unknown 71909510 Common - Response regulator receiver Daro_3899 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 71908931 Nonpathogen - hypothetical protein Daro_3319 1 None None None 71906399 Nonpathogen - hypothetical protein Daro_0760 2 None None None 71909221 Common - Rhs element Vgr protein Daro_3609 48 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 71908225 Common - Radical SAM:Molybdenum cofactor synthesis C-terminal Daro_2612 199 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 71909725 Common - Protein of unknown function DUF1243 Daro_4116 29 COG3165 COG3165, Uncharacterized protein conserved in bacteria Function unknown 71907663 Common - elongation factor P Daro_2035 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 71909546 Common - PfkB Daro_3935 118 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 71908787 Common - Phosphoribosylformylglycinamidine cyclo-ligase Daro_3174 232 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 71908253 Common - Low molecular weight phosphotyrosine protein phosphatase Daro_2640 120 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 71905669 Common - hypothetical protein Daro_0027 20 None None None 71905663 Common - Formylmethionine deformylase Daro_0021 212 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 71909650 Common - YeeE/YedE Daro_4041 45 COG2391 COG2391, Predicted transporter component General function prediction only 71907488 Common - Protein of unknown function DUF1330 Daro_1859 29 COG5470 COG5470, Uncharacterized conserved protein Function unknown 71908712 Common - PAS:GGDEF Daro_3099 197 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 71905910 Common - FAD linked oxidase, C-terminal:FAD linked oxidase, N-terminal Daro_0268 202 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 71907775 Common - Binding-protein-dependent transport systems inner membrane component Daro_2152 195 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 71908639 Common - Conserved hypothetical protein 2281, catalytic Daro_3026 54 COG3577 COG3577, Predicted aspartyl protease General function prediction only 71905992 Common - Membrane protein involved in aromatic hydrocarbon degradation Daro_0350 78 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 71905925 Common - Acetyl-CoA hydrolase/transferase Daro_0283 100 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 71906586 Common - Triosephosphate isomerase Daro_0947 217 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 71908045 Common - Acyltransferase 3 Daro_2427 15 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 71909584 Common - Ni-Fe hydrogenase, small subunit:Twin-arginine translocation pathway signal Daro_3974 77 COG1740 HyaA, Ni,Fe-hydrogenase I small subunit Energy production and conversion 71908459 Common - hypothetical protein Daro_2846 31 None None None 71906721 Nonpathogen - hypothetical protein Daro_1082 1 None None None 71907468 Common - cytochrome C biogenesis protein Daro_1839 153 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 71906163 Common - Catalase, N-terminal Daro_0523 127 COG0753 KatE, Catalase Inorganic ion transport and metabolism 71908541 Nonpathogen - hypothetical protein Daro_2928 1 None None None 71908697 Nonpathogen - hypothetical protein Daro_3084 2 None None None 71908701 Common - SirA-like Daro_3088 127 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 71909633 Common - TRAP dicarboxylate transporter- DctP subunit Daro_4023 92 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 71906660 Common - Coenzyme A transferase Daro_1021 113 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 71908552 Common - hypothetical protein Daro_2939 21 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 71908689 Common - RNA polymerase factor sigma-70 Daro_3076 76 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 71906852 Common - probable integral membrane protein Daro_1213 21 COG3235 COG3235, Predicted membrane protein Function unknown 71909643 Common - ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Daro_4033 141 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 71909188 Common - TRAP C4-dicarboxylate transport system permease DctM subunit Daro_3576 117 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 71907538 Common - PAS:GGDEF Daro_1909 194 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 71907104 Common - Electron transport protein SCO1/SenC Daro_1472 102 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 71908578 Common - hypothetical protein Daro_2965 3 None None None 71907005 Nonpathogen - hypothetical protein Daro_1373 2 None None None 71909736 Common - EAL Daro_4127 34 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 71905965 Common rpsS 30S ribosomal protein S19 Daro_0323 245 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 71908925 Common - hypothetical protein Daro_3312 43 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 71907623 Common - metallo-beta-lactamase family protein Daro_1994 32 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 71906611 Common - PAS:GGDEF Daro_0972 225 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 71908108 Common - regulatory protein, LuxR:Response regulator receiver Daro_2491 213 COG4566 TtrR, Response regulator Signal transduction mechanisms 71908777 Common - DNA mismatch repair protein Daro_3164 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 71906226 Common - glycogen branching enzyme Daro_0586 149 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 71907881 Common - Protein of unknown function DUF411 Daro_2261 64 COG3019 COG3019, Predicted metal-binding protein General function prediction only 71905878 Common - hypothetical protein Daro_0236 4 None None None 71905871 Common - GPR1/FUN34/YaaH family protein Daro_0229 52 COG1584 COG1584, Predicted membrane protein Function unknown 71909045 Common - probable signal peptide protein Daro_3433 2 None None None 71906997 Nonpathogen - hypothetical protein Daro_1365 1 None None None 71905846 Common hslU ATP-dependent protease ATP-binding subunit Daro_0204 210 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 71907251 Common - acetolactate synthase catalytic subunit Daro_1620 223 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 71905748 Common - Stage II sporulation E Daro_0106 63 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 71905854 Common - Pilus assembly protein, PilO Daro_0212 47 COG3167 PilO, Tfp pilus assembly protein PilO Cell motility and secretion / Intracellular trafficking and secretion 71907964 Common - Menaquinone biosynthesis protein Daro_2345 111 COG1165 MenD, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase Coenzyme metabolism 71908101 Nonpathogen - hypothetical protein Daro_2483 1 None None None 71907626 Common - Protozoan/cyanobacterial globin Daro_1997 70 COG2346 COG2346, Truncated hemoglobins General function prediction only 71908236 Common - thioredoxin:cytochrome c biogenesis protein transmembrane region Daro_2623 58 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 71906967 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Daro_1335 26 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 71906808 Common - Aromatic-ring hydroxylase Daro_1169 40 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 71907409 Common - Helicase c2:DEAD/DEAH box helicase, N-terminal Daro_1779 140 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 71909311 Common - GAF Daro_3699 14 COG3605 PtsP, Signal transduction protein containing GAF and PtsI domains Signal transduction mechanisms 71909755 Common - HPr kinase/phosphorylase Daro_4146 72 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 71906087 Common - indolepyruvate oxidoreductase subunit B Daro_0447 65 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 71908376 Nonpathogen - hypothetical protein Daro_2763 1 None None None 71907923 Nonpathogen - hypothetical protein Daro_2304 2 None None None 71909155 Common - Glycosyl transferase, group 1 Daro_3543 207 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 71909745 Common - hypothetical protein Daro_4136 13 None None None 71908669 Common - hypothetical protein Daro_3056 15 None None None 71906444 Common - Cobyrinic acid a,c-diamide synthase Daro_0805 99 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 71909699 Common - TonB-dependent receptor Daro_4090 122 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 71905835 Common - Protein of unknown function DUF484 Daro_0193 54 COG3159 COG3159, Uncharacterized protein conserved in bacteria Function unknown 71906052 Nonpathogen - hypothetical protein Daro_0412 2 None None None 71909099 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein Daro_3487 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 71905882 Common - Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal:Hpt Daro_0240 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71907124 Common - Electron transport complex, RnfABCDGE type, A subunit Daro_1492 76 COG4657 RnfA, Predicted NADH:ubiquinone oxidoreductase, subunit RnfA Energy production and conversion 71907231 Common - Protein of unknown function DUF748 Daro_1599 44 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 71908080 Common - PHP, C-terminal Daro_2462 120 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 71906520 Nonpathogen - hypothetical protein Daro_0881 1 None None None 71907940 Common - hypothetical protein Daro_2321 4 None None None 71906075 Common - hypothetical protein Daro_0435 36 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 71909163 Common - Glycosyl transferase, family 39 Daro_3551 81 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 71905968 Common rplP 50S ribosomal protein L16 Daro_0326 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 71906740 Common - hypothetical protein Daro_1101 15 None None None 71906885 Common - GCN5-related N-acetyltransferase Daro_1247 40 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 71907307 Common - Protein of unknown function DUF894, DitE:Major facilitator superfamily MFS_1 Daro_1677 125 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 71909059 Common - glutaminyl-tRNA synthetase Daro_3447 248 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 71907659 Common recO DNA repair protein RecO Daro_2031 61 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 71907289 Common - hypothetical protein Daro_1658 10 None None None 71907089 Common - flavodoxin FldA Daro_1457 66 COG0716 FldA, Flavodoxins Energy production and conversion 71909667 Nonpathogen - hypothetical protein Daro_4058 6 COG1805 NqrB, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB Energy production and conversion 71908644 Common - argininosuccinate synthase Daro_3031 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 71907324 Common - Cobalt transport protein ATP-binding subunit Daro_1694 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 71909791 Common - anaerobic C4-dicarboxylate transporter Daro_4182 36 COG2704 DcuB, Anaerobic C4-dicarboxylate transporter General function prediction only 71906395 Common flgI flagellar basal body P-ring protein Daro_0756 104 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 71906362 Common motB flagellar motor protein MotB Daro_0723 105 COG1360 MotB, Flagellar motor protein Cell motility and secretion 71908199 Common - Helix-turn-helix, Fis-type Daro_2585 222 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 71906348 Common - GGDEF Daro_0709 205 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 71905801 Common - Glycosyl transferase, family 9 Daro_0159 76 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 71909709 Common - hypothetical protein Daro_4100 30 COG3115 ZipA, Cell division protein Cell division and chromosome partitioning 71907238 Common - Zinc transporter ZIP Daro_1606 93 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 71909304 Common - Sulphate transport system permease protein 2:Sulfate ABC transporter, permease protein CysT Daro_3692 237 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 71906747 Common - hypothetical protein Daro_1108 116 COG3972 COG3972, Superfamily I DNA and RNA helicases General function prediction only 71906281 Common - Cytochrome c assembly protein Daro_0641 77 COG4137 COG4137, ABC-type uncharacterized transport system, permease component General function prediction only 71908511 Common - Alpha/beta hydrolase fold:Thioesterase Daro_2898 139 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 71906034 Common - Phospholipase D/Transphosphatidylase Daro_0392 21 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 71908020 Common - ATPas Daro_2401 68 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 71907514 Common - Major facilitator superfamily MFS_1 Daro_1885 108 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 71907974 Common - AMP-dependent synthetase and ligase Daro_2355 211 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 71907141 Nonpathogen - Protein of unknown function DUF683 Daro_1509 3 None None None 71907949 Common - TraH Daro_2330 24 None None None 71907734 Common - Transposase, IS4 Daro_2108 46 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 71907549 Common - exonuclease subunit SbcD Daro_1920 111 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 71908400 Common - Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal:Hpt Daro_2787 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71907019 Nonpathogen - probable alginate regulatory protein Daro_1387 1 None None None 71906341 Common - Redox-active disulfide protein 2 Daro_0702 67 None None None 71909067 Common - Endoribonuclease L-PSP Daro_3455 94 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 71908815 Common - ABC transporter, transmembrane region:ABC transporter related Daro_3202 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 71909778 Common - Phosphopantetheine-binding Daro_4169 13 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 71906674 Nonpathogen - hypothetical protein Daro_1035 8 None None None 71908150 Common - PilT protein, N-terminal Daro_2534 56 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 71908391 Common - ring hydroxylating dioxygenase, alpha subunit:Rieske (2Fe-2S) region Daro_2778 80 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 71908992 Common - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase Daro_3380 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 71908596 Common - putative transmembrane protein Daro_2983 75 COG2976 COG2976, Uncharacterized protein conserved in bacteria Function unknown 71905750 Common - Peptidase U32 Daro_0108 52 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 71909788 Common - Polysaccharide deacetylase Daro_4179 105 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 71907505 Common - Secretion protein HlyD Daro_1876 118 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 71907039 Common - hypothetical protein Daro_1407 7 None None None 71906682 Common - Cation efflux protein Daro_1043 207 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 71905930 Common - Lipoate-protein ligase B Daro_0288 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 71909080 Common - Pseudouridine synthase, Rsu Daro_3468 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 71906127 Common - regulatory protein, MerR Daro_0487 41 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 71909007 Common - ABC-2 Daro_3395 136 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 71907212 Common - ATP-binding region, ATPase-like:Histidine kinase A, N-terminal Daro_1580 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71908943 Common - Glutamate-ammonia ligase adenylyltransferase Daro_3331 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 71907717 Common - Carbonic anhydrase, prokaryotic and plant Daro_2091 155 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 71907724 Common - bifunctional enoyl-CoA hydratase/phosphate acetyltransferase Daro_2098 152 COG0280 Pta, Phosphotransacetylase Energy production and conversion 71908505 Common - Rhodanese-like Daro_2892 76 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 71909089 Common - anthranilate synthase component II Daro_3477 237 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 71905922 Common - NAD-dependent epimerase/dehydratase:3-beta hydroxysteroid dehydrogenase/isomerase Daro_0280 80 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 71906358 Nonpathogen - hypothetical protein Daro_0719 1 None None None 71908983 Common - Peptidase S1 and S6, chymotrypsin/Hap:PDZ/DHR/GLGF Daro_3371 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 71906902 Common - NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR:3-beta hydroxysteroid dehydrogenase/isomerase:Polysaccharide biosynthesis protein CapD:dTDP-4-dehydrorhamnose reductase Daro_1264 199 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 71905724 Nonpathogen - hypothetical protein Daro_0082 1 None None None 71905858 Common - 3-dehydroquinate synthase Daro_0216 209 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 71908358 Common - Oxidoreductase FAD-binding region Daro_2745 50 COG4097 COG4097, Predicted ferric reductase Inorganic ion transport and metabolism 71906626 Common - ABC-2:ABC transporter related Daro_0987 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 71908805 Common - putative additional subunit of nitric oxide reductase (Nor) complex, membrane protein Daro_3192 156 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 71909116 Common - Penicillin-binding protein, transpeptidase:Penicillin-binding protein, dimerization domain Daro_3504 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 71909226 Common - putative phage tail sheath protein FI Daro_3614 39 COG3497 COG3497, Phage tail sheath protein FI General function prediction only 71907014 Common - Glutathione S-transferase, N-terminal Daro_1382 24 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 71906689 Common - UspA Daro_1050 108 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 71908324 Common - GETHR pentapeptide Daro_2711 17 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 71906254 Common - Protein of unknown function DUF1058 Daro_0614 25 COG3807 COG3807, Uncharacterized protein conserved in bacteria Function unknown 71905832 Common - lipid A biosynthesis acyltransferase Daro_0190 117 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 71908473 Common - Citrate synthase I Daro_2860 194 COG0372 GltA, Citrate synthase Energy production and conversion 71906700 Common - Bacterioferritin Daro_1061 97 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 71905993 Nonpathogen - hypothetical protein Daro_0351 1 None None None 71909090 Common - hypothetical protein Daro_3478 33 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 71905961 Common rplC 50S ribosomal protein L3 Daro_0319 223 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 71907098 Nonpathogen - hypothetical protein Daro_1466 1 None None None 71909328 Common - Protein of unknown function DUF214 Daro_3716 91 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 71909365 Common - Protein of unknown function DUF350 Daro_3753 28 COG3766 COG3766, Predicted membrane protein Function unknown 71909454 Common - RelA/SpoT protein Daro_3843 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 71906811 Common - Beta-ketoacyl synthase Daro_1172 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 71908265 Common - hypothetical protein Daro_2652 7 None None None 71909035 Common - Phasin Daro_3423 16 None None None 71907864 Common - Protein of unknown function DUF1173 Daro_2244 16 None None None 71907609 Common ompR osmolarity response regulator Daro_1980 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 71907753 Common - Phospholipase/Carboxylesterase Daro_2128 91 COG0400 COG0400, Predicted esterase General function prediction only 71907654 Common - GTP-binding protein LepA Daro_2026 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 71909194 Common - Phenylacetic acid degradation-related protein Daro_3582 70 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 71909402 Common - regulatory protein GntR, HTH:GntR, C-terminal Daro_3790 121 COG1802 GntR, Transcriptional regulators Transcription 71907560 Nonpathogen - hypothetical protein Daro_1931 1 None None None 71907091 Nonpathogen - hypothetical protein Daro_1459 3 None None None 71907557 Common - Appr-1-p processing Daro_1928 116 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 71907188 Nonpathogen - hypothetical protein Daro_1556 1 None None None 71908946 Common - putative aminotransferase Daro_3334 236 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 71906486 Common - NlpBDapX lipoprotein Daro_0847 31 COG3317 NlpB, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 71906351 Common - Cytochrome oxidase maturation protein cbb3-type Daro_0712 42 COG3197 FixS, Uncharacterized protein, possibly involved in nitrogen fixation Inorganic ion transport and metabolism 71907351 Nonpathogen - hypothetical protein Daro_1721 1 None None None 71907586 Common - hypothetical protein Daro_1957 42 COG3651 COG3651, Uncharacterized protein conserved in bacteria Function unknown 71907741 Common - Beta-lactamase Daro_2115 41 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 71907917 Common - Response regulator receiver:Transcriptional regulatory protein, C-terminal Daro_2298 206 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 71907080 Common - NifQ Daro_1448 23 None None None 71905823 Common - Twin-arginine translocation pathway signal Daro_0181 115 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 71909537 Common - Type I secretion outer membrane protein, TolC Daro_3926 142 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 71909070 Common - Response regulator receiver:Metal-dependent phosphohydrolase, HD subdomain Daro_3458 223 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 71908822 Common - Biopolymer transport protein ExbD/TolR Daro_3209 135 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 71906469 Common - Twin-arginine translocation pathway signal Daro_0830 93 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 71907001 Nonpathogen - hypothetical protein Daro_1369 4 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 71908999 Common - Histidinol dehydrogenase Daro_3387 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 71908283 Common - regulatory protein, MerR Daro_2670 89 COG0789 SoxR, Predicted transcriptional regulators Transcription 71906908 Common - Glycosyl transferase, family 2 Daro_1273 142 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 71907429 Common - putative ABC transporter ATP-binding protein Daro_1799 247 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 71909206 Common - Phosphoglycerate kinase Daro_3594 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 71907267 Common - hypothetical protein Daro_1636 5 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 71907126 Common - Electron transport complex, RnfABCDGE type, C subunit Daro_1494 77 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 71906169 Common rpsU 30S ribosomal protein S21 Daro_0529 103 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 71906007 Common - ABC transporter related Daro_0365 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 71909723 Common - F0F1 ATP synthase subunit beta Daro_4114 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 71909764 Common - Na+/solute symporter Daro_4155 182 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 71907906 Nonpathogen - hypothetical protein Daro_2286 2 None None None 71907071 Nonpathogen - hypothetical protein Daro_1439 3 None None None 71906247 Nonpathogen - hypothetical protein Daro_0607 3 None None None 71906471 Common - Nitrate transport ATP-binding subunits C and D Daro_0832 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 71907632 Common - excinuclease ABC subunit B Daro_2003 228 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 71908758 Common - Disulphide bond formation protein DsbB Daro_3145 50 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 71908782 Common - TrkA-N:Sodium/hydrogen exchanger Daro_3169 204 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 71907872 Common - Heavy metal efflux pump CzcA Daro_2252 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 71907694 Common - OsmC-like protein Daro_2067 84 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 71906647 Common - Aldehyde dehydrogenase Daro_1008 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 71906924 Common - Inorganic pyrophosphatase Daro_1289 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 71907096 Common - probable transmembrane protein Daro_1464 24 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 71906959 Nonpathogen - hypothetical protein Daro_1326 2 None None None 71909015 Common - Helix-turn-helix, Fis-type Daro_3403 169 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 71906153 Common - hypothetical protein Daro_0513 21 COG3897 COG3897, Predicted methyltransferase General function prediction only 71906049 Common - Radical SAM Daro_0409 101 COG1964 COG1964, Predicted Fe-S oxidoreductases General function prediction only 71909391 Common - Glycosyl hydrolase, BNR repeat Daro_3779 38 COG4447 COG4447, Uncharacterized protein related to plant photosystem II stability/assembly factor General function prediction only 71908952 Common - NADP oxidoreductase, coenzyme F420-dependent:6-phosphogluconate dehydrogenase, NAD-binding Daro_3340 187 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 71909127 Common - Twin-arginine translocation pathway signal:Periplasmic nitrate reductase, large subunit Daro_3515 183 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 71906120 Common - Sodium:dicarboxylate symporter Daro_0480 163 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 71908364 Common - hypothetical protein Daro_2751 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 71907041 Nonpathogen - hypothetical protein Daro_1409 5 None None None 71908967 Common - CHAD:Adenylate cyclase Daro_3355 93 COG3025 COG3025, Uncharacterized conserved protein Function unknown 71909576 Common - Hydrogenase formation HypD protein Daro_3966 109 COG0409 HypD, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 71909387 Common - 3-isopropylmalate dehydrogenase Daro_3775 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 71909515 Common - Cyclic nucleotide-binding:Sulfate transporter/antisigma-factor antagonist STAS:Xanthine/uracil/vitamin C permease:Sulphate transporter Daro_3904 158 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 71907956 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein Daro_2337 239 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 71909789 Common - hypothetical protein Daro_4180 9 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 71909326 Common - PAS Daro_3714 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71907199 Common - Periplasmic copper-binding Daro_1567 50 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 71909218 Common - hypothetical protein Daro_3606 10 None None None 71906134 Common - Major facilitator superfamily MFS_1 Daro_0494 21 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 71907370 Common - methionine aminopeptidase Daro_1740 247 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 71907201 Common - Cytochrome c, class I Daro_1569 56 COG2863 COG2863, Cytochrome c553 Energy production and conversion 71907643 Common - 3-oxoacyl-(acyl carrier protein) synthase III Daro_2015 210 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 71906295 Common - UBA/THIF-type NAD/FAD binding fold Daro_0656 155 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 71907028 Common - hypothetical protein Daro_1396 12 None None None 71906218 Common - Orn/Lys/Arg decarboxylase, major region:Orn/Lys/Arg decarboxylase, C-terminal Daro_0578 86 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 71909660 Common - hypothetical protein Daro_4051 98 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 71905696 Common - Ammonium transporter Daro_0054 203 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 71908172 Nonpathogen - hypothetical protein Daro_2556 2 None None None 71908601 Common - Conserved hypothetical protein 48 Daro_2988 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 71907700 Common - NAD(P)H dehydrogenase (quinone):NADPH-dependent FMN reductase Daro_2073 123 COG0431 COG0431, Predicted flavoprotein General function prediction only 71908146 Common - hypothetical protein Daro_2530 19 None None None 71906428 Common - BRO, N-terminal Daro_0789 40 COG3617 COG3617, Prophage antirepressor Transcription 71908132 Common - Histone deacetylase superfamily Daro_2516 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 71906059 Common - hypothetical protein Daro_0419 30 COG3671 COG3671, Predicted membrane protein Function unknown 71909247 Common - hypothetical protein Daro_3635 5 None None None 71907702 Common - Cupin region Daro_2075 19 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 71909440 Common - Secretion protein HlyD Daro_3829 157 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 71906934 Common - hypothetical protein Daro_1299 22 None None None 71907746 Common - Protein of unknown function DUF924, bacterial Daro_2121 63 COG3803 COG3803, Uncharacterized protein conserved in bacteria Function unknown 71906532 Common - type II and III secretion system protein:Secretin, N-terminal:Secretin/TonB, short N-terminal Daro_0893 108 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 71909375 Common - Glutamine synthetase type I Daro_3763 227 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 71907066 Common - ABC transporter related Daro_1434 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 71909265 Common - ATPas Daro_3653 7 COG4916 COG4916, Uncharacterized protein containing a TIR (Toll-Interleukin 1-resistance) domain Function unknown 71907136 Nonpathogen - Legume lectin, beta domain:Protein of unknown function DUF1555 Daro_1504 6 None None None 71908894 Common secF preprotein translocase subunit SecF Daro_3281 201 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 71909741 Common - Lytic transglycosylase, catalytic Daro_4132 158 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 71907208 Common - hypothetical protein Daro_1576 10 None None None 71909294 Nonpathogen - hypothetical protein Daro_3682 1 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 71907400 Common - Lipolytic enzyme, G-D-S-L Daro_1770 42 COG3240 COG3240, Phospholipase/lecithinase/hemolysin Lipid metabolism / General function prediction only 71909050 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Daro_3438 28 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 71907190 Common - hypothetical protein Daro_1558 41 COG3672 COG3672, Predicted periplasmic protein Function unknown 71909586 Common - hypothetical protein Daro_3976 11 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 71908159 Nonpathogen - hypothetical protein Daro_2543 1 None None None 71905736 Common - DSBA oxidoreductase Daro_0094 55 COG3917 NahD, 2-hydroxychromene-2-carboxylate isomerase Secondary metabolites biosynthesis, transport, and catabolism 71908243 Common - Peptidase A8, signal peptidase II Daro_2630 192 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 71906871 Common - Chorismate mutase, gamma, beta and epsilon proteobacteria Daro_1232 212 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 71908518 Common - BolA-like protein Daro_2905 22 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 71907422 Common - YaeQ Daro_1792 52 COG4681 COG4681, Uncharacterized protein conserved in bacteria Function unknown 71908661 Common - GGDEF Daro_3048 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 71907430 Nonpathogen - hypothetical protein Daro_1800 6 None None None 71908737 Common - NAD(P) transhydrogenase, beta subunit Daro_3124 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 71906754 Common - MotA/TolQ/ExbB proton channel Daro_1115 131 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 71906511 Common - Acetyl-CoA carboxylase carboxyl transferase, beta subunit Daro_0872 217 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 71908077 Common - tryptophanyl-tRNA synthetase Daro_2459 235 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 71909318 Common - hypothetical protein Daro_3706 207 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 71907709 Nonpathogen - hypothetical protein Daro_2082 1 None None None 71909461 Common - Protein phosphatase 2C-like Daro_3850 129 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 71906440 Nonpathogen - hypothetical protein Daro_0801 2 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 71907377 Common - Phosphatidate cytidylyltransferase Daro_1747 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 71906529 Common - hypothetical protein Daro_0890 5 None None None 71907588 Common - hypothetical protein Daro_1959 36 COG4628 COG4628, Uncharacterized conserved protein Function unknown 71906238 Common - Twin-arginine translocation pathway signal Daro_0598 92 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 71906568 Common hemH ferrochelatase Daro_0929 162 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 71906306 Common - Peptidase S11, D-alanyl-D-alanine carboxypeptidase 1 Daro_0667 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 71906831 Common - putative poly-gamma-glutamate biosynthesis enzyme Daro_1192 77 COG2843 PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) Cell envelope biogenesis, outer membrane 71906082 Common aceE pyruvate dehydrogenase subunit E1 Daro_0442 137 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 71907985 Common - CTP synthetase Daro_2366 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 71905818 Common - Enoyl-CoA hydratase/isomerase Daro_0176 185 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 71905959 Common tuf elongation factor Tu Daro_0317 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 71906405 Common fliM flagellar motor switch protein FliM Daro_0766 113 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 71909386 Common - thiol-disulfide isomerase-like protein Daro_3774 165 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 71906550 Common - Alpha/beta hydrolase fold Daro_0911 163 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 71907252 Nonpathogen - hypothetical protein Daro_1621 1 None None None 71907930 Common - Lytic transglycosylase, catalytic Daro_2311 39 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 71908087 Common - Protein of unknown function DUF480 Daro_2469 41 COG3132 COG3132, Uncharacterized protein conserved in bacteria Function unknown 71909417 Common - Aldehyde dehydrogenase Daro_3806 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 71909447 Common - Fungal/archaeal/bacterial haem catalase/peroxidase Daro_3836 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 71909624 Common - Acyl transferase region Daro_4014 135 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 71906209 Nonpathogen - hypothetical protein Daro_0569 1 None None None 71907973 Common - Enoyl-CoA hydratase/isomerase Daro_2354 176 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 71909646 Common - Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidine kinase A, N-terminal Daro_4037 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71908793 Common - hypothetical protein Daro_3180 80 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 71908845 Common - Phenylacetic acid degradation-related protein Daro_3232 92 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 71906023 Common - Ferredoxin:Oxidoreductase FAD/NAD(P)-binding:Oxidoreductase FAD-binding region Daro_0381 136 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 71906640 Common - cytochrome c550 Daro_1001 14 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 71908260 Nonpathogen - TraL Daro_2647 5 None None None 71905643 Common - chromosomal replication initiator protein, DnaA Daro_0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 71908608 Common - PAS Daro_2995 223 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 71906549 Common - Hemerythrin HHE cation binding region Daro_0910 13 COG3945 COG3945, Uncharacterized conserved protein Function unknown 71909488 Common - Cytochrome c, class I Daro_3877 45 COG3245 CycB, Cytochrome c5 Energy production and conversion 71908483 Common - CBS Daro_2870 132 COG0517 COG0517, FOG: CBS domain General function prediction only 71908884 Common - hypothetical protein Daro_3271 17 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 71907851 Common - hypothetical protein Daro_2229 6 None None None 71907275 Common - regulatory protein, LysR:LysR, substrate-binding Daro_1644 174 COG0583 LysR, Transcriptional regulator Transcription 71907572 Common - TPR repeat:Tetratricopeptide TPR_4 Daro_1943 114 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 71908215 Common - Phosphonate-binding periplasmic protein Daro_2602 47 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 71908181 Common - hypothetical protein Daro_2565 8 None None None 71907260 Common - acetyl-CoA synthetase Daro_1629 214 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 71908751 Common - Cytochrome c, class I Daro_3138 61 COG2863 COG2863, Cytochrome c553 Energy production and conversion 71908887 Common - Cytochrome d1, heme region Daro_3274 20 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 71907161 Common - General substrate transporter:Major facilitator superfamily MFS_1 Daro_1529 232 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 71908698 Common valS valyl-tRNA synthetase Daro_3085 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 71908072 Common - hypothetical protein Daro_2454 151 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 71905905 Common - hypothetical protein Daro_0263 14 None None None 71906174 Common - Dihydroneopterin aldolase Daro_0534 107 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 71908533 Common - hypothetical protein Daro_2920 15 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 71908313 Nonpathogen - hypothetical protein Daro_2700 1 None None None 71906684 Common - hypothetical protein Daro_1045 14 None None None 71906797 Common - SoxR-reducing system protein RsxE Daro_1158 76 COG4660 RnfE, Predicted NADH:ubiquinone oxidoreductase, subunit RnfE Energy production and conversion 71905786 Common - cobyric acid synthase Daro_0144 151 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 71907512 Common - hypothetical protein Daro_1883 18 COG0824 FcbC, Predicted thioesterase General function prediction only 71908382 Common - ABC transporter related Daro_2769 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 71906718 Common - Response regulator receiver:Transcriptional regulatory protein, C-terminal Daro_1079 204 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 71908009 Common - hypothetical protein Daro_2390 25 None None None 71909449 Common napH quinol dehydrogenase membrane component Daro_3838 88 COG0348 NapH, Polyferredoxin Energy production and conversion 71906543 Common - Extracellular ligand-binding receptor Daro_0904 125 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 71908286 Common pheS phenylalanyl-tRNA synthetase subunit alpha Daro_2673 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 71906002 Common - 4-oxalocrotonate tautomerase Daro_0360 34 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 71909379 Common - Endonuclease/exonuclease/phosphatase Daro_3767 65 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 71908586 Common - hypothetical protein Daro_2973 4 None None None 71908855 Common - Hydratase/decarboxylase Daro_3242 67 COG3971 COG3971, 2-keto-4-pentenoate hydratase Secondary metabolites biosynthesis, transport, and catabolism 71907453 Common - Phosphonate uptake transporter Daro_1824 88 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 71906576 Common - Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase A, N-terminal:Hpt Daro_0937 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71908000 Common - SAM-dependent methyltransferase Daro_2381 67 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 71905952 Common rplJ 50S ribosomal protein L10 Daro_0310 211 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 71906384 Common - flagellar motor protein MotD Daro_0745 157 COG1360 MotB, Flagellar motor protein Cell motility and secretion 71906285 Common - dinucleoside polyphosphate hydrolase Daro_0645 111 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 71909729 Common - Histidine triad (HIT) protein Daro_4120 79 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 71909025 Nonpathogen - general secretion pathway protein H Daro_3413 7 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 71908059 Common - Lytic transglycosylase, catalytic Daro_2441 177 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 71906411 Common - Flagellar motor switch protein FliG Daro_0772 125 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 71908830 Common - Prokaryotic N-terminal methylation site Daro_3217 26 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 71908160 Nonpathogen - hypothetical protein Daro_2544 2 None None None 71906741 Common - Metal-dependent phosphohydrolase, HD subdomain Daro_1102 60 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 71907331 Common - Coenzyme PQQ synthesis D Daro_1701 15 None None None 71905864 Common - elongation factor G Daro_0222 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 71909559 Common - Protein of unknown function DUF59 Daro_3948 152 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 71908919 Common - extracellular solute-binding protein, family 1 Daro_3306 66 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 71909554 Common - malic enzyme Daro_3943 214 COG0281 SfcA, Malic enzyme Energy production and conversion 71909245 Common - hypothetical protein Daro_3633 5 None None None 71908300 Nonpathogen - hypothetical protein Daro_2687 1 None None None 71906987 Common - acetaldehyde dehydrogenase Daro_1355 37 COG4569 MhpF, Acetaldehyde dehydrogenase (acetylating) Secondary metabolites biosynthesis, transport, and catabolism 71906652 Nonpathogen - hypothetical protein Daro_1013 1 None None None 71905916 Common - ABC transporter related Daro_0274 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 71909714 Common - Cobyrinic acid a,c-diamide synthase Daro_4105 232 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 71908248 Nonpathogen - hypothetical protein Daro_2635 7 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 71906730 Common - hypothetical protein Daro_1091 23 None None None 71906737 Common - Protein of unknown function DUF6, transmembrane Daro_1098 84 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 71906502 Common leuD isopropylmalate isomerase small subunit Daro_0863 209 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 71907110 Common - Molybdenum-pterin binding protein Daro_1478 78 COG3585 MopI, Molybdopterin-binding protein Coenzyme metabolism 71908910 Common - hypothetical protein Daro_3297 16 COG4319 COG4319, Ketosteroid isomerase homolog Function unknown 71906868 Common - N-ethylammeline chlorohydrolase Daro_1229 177 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 71907684 Common - Twin-arginine translocation pathway signal Daro_2057 47 COG2930 COG2930, Uncharacterized conserved protein Function unknown 71906645 Common - Cytochrome c, class I Daro_1006 28 COG4654 COG4654, Cytochrome c551/c552 Energy production and conversion 71907021 Common - DedA Daro_1389 15 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 71907618 Common - Protein of unknown function DUF214 Daro_1989 88 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 71906377 Common - CheW-like protein:ATP-binding region, ATPase-like:Signal transducing histidine kinase, homodimeric:Hpt Daro_0738 150 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 71905825 Common - 5,10-methylenetetrahydrofolate reductase Daro_0183 144 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 71906848 Common - putative lipoprotein Daro_1209 16 COG3218 COG3218, ABC-type uncharacterized transport system, auxiliary component General function prediction only 71906141 Common - Phosphoheptose isomerase Daro_0501 123 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 71905868 Common - acyl-CoA synthetase Daro_0226 219 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 71906790 Common - type II secretion system protein E:General secretory system II, protein E, N-terminal Daro_1151 184 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 71907168 Common - Oxidoreductase FAD/NAD(P)-binding:Oxidoreductase FAD-binding region Daro_1536 117 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 71908774 Common - Phosphoribosylglycinamide formyltransferase Daro_3161 220 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 71906873 Common - Prephenate dehydrogenase:Ketopantoate reductase ApbA/PanE:NAD-dependent glycerol-3-phosphate dehydrogenase, N-terminal Daro_1234 166 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 71909734 Common - AzlC-like Daro_4125 61 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 71907385 Common - Glycosyl transferase, family 19 Daro_1755 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 71905976 Common rplF 50S ribosomal protein L6 Daro_0334 238 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 71906090 Common - Small multidrug resistance protein Daro_0450 140 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 71907759 Common - regulatory protein, ArsR Daro_2135 156 COG0640 ArsR, Predicted transcriptional regulators Transcription 71908329 Common - hypothetical protein Daro_2716 38 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 71906914 Common - bifunctional 3-phosphoshikimate 1-carboxyvinyltransferase/cytidine monophosphate kinase Daro_1279 242 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 71906009 Common - inner-membrane translocator Daro_0367 149 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 71907229 Common - GGDEF Daro_1597 222 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 71909170 Common - ATP-binding region, ATPase-like:Histidine kinase A, N-terminal Daro_3558 219 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 71906977 Common - Flavin reductase-like, FMN-binding Daro_1345 112 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 71908756 Common rpmB 50S ribosomal protein L28 Daro_3143 164 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 71906919 Common - UDP-glucose/GDP-mannose dehydrogenase Daro_1284 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 71906947 Nonpathogen - hypothetical protein Daro_1313 1 None None None 71909521 Common - hypothetical protein Daro_3910 50 COG3150 COG3150, Predicted esterase General function prediction only 71906992 Common - Amidase Daro_1360 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 71907604 Common - 2',5' RNA ligase Daro_1975 89 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 71908203 Common - Protein of unknown function DUF1109 Daro_2589 20 COG4944 COG4944, Uncharacterized protein conserved in bacteria Function unknown 71909803 Common - Phospholipid/glycerol acyltransferase Daro_4194 49 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 71905652 Common - glutathione synthetase Daro_0010 118 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 71907117 Common - ferredoxin, 2Fe-2S Daro_1485 78 COG3411 COG3411, Ferredoxin Energy production and conversion 71907678 Nonpathogen - Protein of unknown function DUF883, ElaB Daro_2050 1 COG4575 ElaB, Uncharacterized conserved protein Function unknown 71906628 Nonpathogen - hypothetical protein Daro_0989 1 None None None 71908118 Nonpathogen - hypothetical protein Daro_2501 2 None None None 71906516 Common - O-succinylhomoserine sulfhydrylase Daro_0877 207 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 71907791 Common - Rhs element Vgr protein Daro_2169 54 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 71906607 Common - MglA protein Daro_0968 19 COG2229 COG2229, Predicted GTPase General function prediction only 71907181 Common - Enoyl-CoA hydratase/isomerase:3-hydroxyacyl-CoA dehydrogenase, C-terminal:3-hydroxyacyl-CoA dehydrogenase, NAD-binding Daro_1549 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 71906010 Common - Ferredoxin:Oxidoreductase FAD/NAD(P)-binding:Oxidoreductase FAD-binding region Daro_0368 125 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 71906369 Common - MCP methyltransferase, CheR-type Daro_0730 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 71909541 Common - NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR:3-beta hydroxysteroid dehydrogenase/isomerase:Polysaccharide biosynthesis protein CapD:dTDP-4-dehydrorhamnose reductase:Nucleotide sugar epimerase Daro_3930 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 71907971 Common - Thiolase Daro_2352 172 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 71908654 Nonpathogen - general secretion pathway protein H Daro_3041 5 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 71909353 Common - Phosphatidylglycerophosphatase A Daro_3741 96 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 71906729 Common - Glutathione peroxidase Daro_1090 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 71908183 Common - Helix-turn-helix motif Daro_2567 15 COG1396 HipB, Predicted transcriptional regulators Transcription 71906861 Common - PhoH-like protein Daro_1222 190 COG1875 COG1875, Predicted ATPase related to phosphate starvation-inducible protein PhoH Signal transduction mechanisms 71909606 Common - Cytochrome c-type biogenesis protein CcmF Daro_3996 138 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 71909774 Common - ABC-2 type transporter, NodJ Daro_4165 134 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 71906400 Common - Flagellar biosynthesis protein FliR Daro_0761 128 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 71906146 Common - dihydroorotase Daro_0506 87 COG0418 PyrC, Dihydroorotase Nucleotide transport and metabolism 71908871 Common - Phospholipase/Carboxylesterase Daro_3258 93 COG0400 COG0400, Predicted esterase General function prediction only 71909507 Common - chemotaxis sensory transducer Daro_3896 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 71907293 Common - PAS:GGDEF Daro_1662 195 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 71909125 Common - NapC/NirT cytochrome c, N-terminal Daro_3513 48 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 71905890 Common - Cyclic nucleotide-binding Daro_0248 75 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 71906455 Common - BFD-like (2Fe-2S)-binding region Daro_0816 217 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 71907887 Common - ATPase, E1-E2 type:Copper-translocating P-type ATPase:Heavy metal translocating P-type ATPase Daro_2267 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 71909592 Common - Rubredoxin-type Fe(Cys)4 protein Daro_3982 115 COG1773 COG1773, Rubredoxin Energy production and conversion 71908170 Common - hypothetical protein Daro_2554 5 None None None 71906357 Common - hypothetical protein Daro_0718 22 COG3198 COG3198, Uncharacterized protein conserved in bacteria Function unknown 71906185 Nonpathogen - hypothetical protein Daro_0545 2 None None None 71907465 Common - ATPase, E1-E2 type:Copper-translocating P-type ATPase:Heavy metal translocating P-type ATPase Daro_1836 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 71907314 Common - TonB-dependent receptor Daro_1684 33 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 71905768 Nonpathogen - hypothetical protein Daro_0126 1 None None None 71906815 Common - Outer membrane efflux protein Daro_1176 38 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 71906559 Common - Extracellular ligand-binding receptor Daro_0920 115 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 71909548 Common prmA ribosomal protein L11 methyltransferase Daro_3937 171 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 71908548 Common fumC fumarate hydratase Daro_2935 213 COG0114 FumC, Fumarase Energy production and conversion 71907834 Common - hypothetical protein Daro_2212 6 None None None 71909442 Common - regulatory protein, LysR:LysR, substrate-binding Daro_3831 170 COG0583 LysR, Transcriptional regulator Transcription 71907806 Common - putative transmembrane protein Daro_2184 3 None None None 71907446 Common - Formate dehydrogenase, beta subunit Daro_1817 159 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 71907660 Common - pyridoxal phosphate biosynthetic protein PdxJ Daro_2032 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 71908978 Common - Phenylacetate-CoA ligase Daro_3366 121 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 71909656 Common - ABC transporter related Daro_4047 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 71905813 Common - Protein of unknown function DUF163 Daro_0171 166 COG1576 COG1576, Uncharacterized conserved protein Function unknown 71909255 Nonpathogen - hypothetical protein Daro_3643 4 None None None 71909183 Common - GGDEF Daro_3571 164 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 71909398 Common - Alpha/beta hydrolase fold Daro_3786 177 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 71909564 Common - Heat shock protein DnaJ, N-terminal Daro_3953 9 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 71906216 Common - Protein of unknown function DUF59 Daro_0576 234 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 71906751 Common - hypothetical protein Daro_1112 12 COG3659 OprB, Carbohydrate-selective porin Cell envelope biogenesis, outer membrane 71907477 Common - Phasin Daro_1848 16 None None None 71906119 Common - Protein of unknown function DUF81 Daro_0479 102 COG0730 COG0730, Predicted permeases General function prediction only 71906261 Common - putative sulfite oxidase subunit YedY Daro_0621 120 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 71905677 Common - Major facilitator superfamily MFS_1 Daro_0035 137 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 71908728 Nonpathogen - hypothetical protein Daro_3115 1 None None None 71906932 Common - hypothetical protein Daro_1297 59 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 71907899 Nonpathogen - hypothetical protein Daro_2279 1 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 71906662 Common - Pyrrolo-quinoline quinone Daro_1023 66 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 71908571 Common - Acriflavin resistance protein Daro_2958 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 71908683 Common - probable transmembrane protein Daro_3070 23 COG3308 COG3308, Predicted membrane protein Function unknown 71908460 Common - PAS Daro_2847 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71905667 Common - Peptidase C56, PfpI Daro_0025 139 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 71905761 Common - hypothetical protein Daro_0119 3 None None None 71906779 Common - chemotaxis sensory transducer Daro_1140 9 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 71907286 Nonpathogen - hypothetical protein Daro_1655 1 COG3941 COG3941, Mu-like prophage protein General function prediction only 71905977 Common rplR 50S ribosomal protein L18 Daro_0335 215 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 71906192 Common - regulatory protein, LysR:LysR, substrate-binding Daro_0552 157 COG0583 LysR, Transcriptional regulator Transcription 71908714 Common - malate synthase Daro_3101 58 COG2225 AceB, Malate synthase Energy production and conversion 71909635 Common - Protein of unknown function DUF81 Daro_4025 124 COG0730 COG0730, Predicted permeases General function prediction only 71907298 Nonpathogen - hypothetical protein Daro_1668 2 None None None 71908554 Common - hypothetical protein Daro_2941 12 None None None 71908576 Common - Protein of unknown function DUF1415 Daro_2963 30 COG3310 COG3310, Uncharacterized protein conserved in bacteria Function unknown 71908633 Common - Protein of unknown function DUF403, bacteria Daro_3020 82 COG2307 COG2307, Uncharacterized protein conserved in bacteria Function unknown 71907665 Common - Uracil-DNA glycosylase superfamily Daro_2037 93 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 71909165 Common - Response regulator receiver:Metal-dependent phosphohydrolase, HD subdomain Daro_3553 224 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 71908438 Common - PAS:GGDEF Daro_2825 223 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 71907035 Common - hypothetical protein Daro_1403 8 None None None 71908817 Common - 6-phosphofructokinase Daro_3204 156 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 71908981 Common - Peptidoglycan-binding LysM Daro_3369 11 COG3170 FimV, Tfp pilus assembly protein FimV Cell motility and secretion / Intracellular trafficking and secretion 71906984 Common - hypothetical protein Daro_1352 17 None None None 71908047 Nonpathogen - hypothetical protein Daro_2429 8 COG5652 COG5652, Predicted integral membrane protein Function unknown 71909464 Common - coproporphyrinogen III oxidase Daro_3853 208 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 71906292 Common - Protein of unknown function DUF583 Daro_0652 37 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 71906850 Common - Electron transfer flavoprotein beta-subunit Daro_1211 153 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 71907485 Common - hypothetical protein Daro_1856 25 COG2519 GCD14, tRNA(1-methyladenosine) methyltransferase and related methyltransferases Translation, ribosomal structure and biogenesis 71908251 Common - Arsenical resistance operon trans-acting repressor ArsD Daro_2638 31 None None None 71906437 Nonpathogen - hypothetical protein Daro_0798 1 None None None 71908043 Common - Transposase IS3/IS911 Daro_2424 60 None None None 71908542 Nonpathogen - hypothetical protein Daro_2929 8 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 71905920 Common - hypothetical protein Daro_0278 6 COG3650 COG3650, Predicted membrane protein Function unknown 71907773 Common - ATP-binding region, ATPase-like:Histidine kinase A, N-terminal Daro_2150 214 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 71905710 Common - Heptaprenyl diphosphate synthase component I Daro_0068 18 COG4769 COG4769, Predicted membrane protein Function unknown 71908935 Common - Cytochrome c, class I:Cytochrome d1, heme region Daro_3323 20 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 71908338 Common - hypothetical protein Daro_2725 40 COG3832 COG3832, Uncharacterized conserved protein Function unknown 71908674 Common - 1-deoxy-D-xylulose-5-phosphate synthase Daro_3061 227 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 71905799 Common - Glycosyl transferase, family 9 Daro_0157 106 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 71906029 Common - hypothetical protein Daro_0387 10 None None None 71908780 Nonpathogen - hypothetical protein Daro_3167 2 None None None 71906324 Common - ATP-binding region, ATPase-like:Histidine kinase A, N-terminal Daro_0685 72 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 71906696 Common - Twin-arginine translocation pathway signal Daro_1057 24 COG3490 COG3490, Uncharacterized protein conserved in bacteria Function unknown 71907105 Common - Antibiotic biosynthesis monooxygenase Daro_1473 35 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 71909618 Nonpathogen - chemotaxis sensory transducer Daro_4008 3 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 71908033 Common - Polysaccharide biosynthesis protein Daro_2414 75 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 71906969 Common - indole acetimide hydrolase Daro_1337 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 71907214 Common - NapC/NirT cytochrome c, N-terminal Daro_1582 47 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 71909429 Common - Rieske (2Fe-2S) region Daro_3818 64 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 71909813 Common rpmH 50S ribosomal protein L34 Daro_4204 192 COG0230 RpmH, Ribosomal protein L34 Translation, ribosomal structure and biogenesis 71908294 Nonpathogen - hypothetical protein Daro_2681 1 None None None 71906828 Common - Protein of unknown function DUF477 Daro_1189 87 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 71906588 Common - NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Daro_0949 163 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 71906723 Common - Conserved hypothetical protein 2001 Daro_1084 36 None None None 71908523 Common - transcriptional regulator CysB-like protein Daro_2910 189 COG0583 LysR, Transcriptional regulator Transcription 71906772 Nonpathogen - hypothetical protein Daro_1133 1 None None None 71909738 Common - Aminotransferase, class I and II Daro_4129 209 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 71908718 Common - LrgA Daro_3105 55 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 71906259 Common - biotin synthesis protein Daro_0619 137 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 71909683 Common - Glutathione-dependent formaldehyde-activating, GFA Daro_4074 57 COG3791 COG3791, Uncharacterized conserved protein Function unknown 71908038 Common - Acyltransferase 3 Daro_2419 14 COG3594 NolL, Fucose 4-O-acetylase and related acetyltransferases Carbohydrate transport and metabolism 71905967 Common rpsC 30S ribosomal protein S3 Daro_0325 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 71906859 Common - DnaB helicase Daro_1220 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 71907866 Common - Prophage CP4-57 regulatory Daro_2246 15 COG3311 AlpA, Predicted transcriptional regulator Transcription 71906300 Common - ATP-binding region, ATPase-like:Histidine kinase A, N-terminal Daro_0661 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71906314 Common - PAS:GGDEF Daro_0675 196 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 71908387 Common - Hydratase/decarboxylase Daro_2774 66 COG3971 COG3971, 2-keto-4-pentenoate hydratase Secondary metabolites biosynthesis, transport, and catabolism 71908620 Common - hypothetical protein Daro_3007 97 COG2081 COG2081, Predicted flavoproteins General function prediction only 71905983 Common - Ribosomal protein L36 Daro_0341 137 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 71906899 Common - Glycosyl transferase, group 1 Daro_1261 167 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 71905713 Common - Peptidase M20D, amidohydrolase Daro_0071 170 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 71908238 Nonpathogen - Nitrogen regulatory protein P-II Daro_2625 3 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 71906045 Common - Phospholipid/glycerol acyltransferase:Major facilitator superfamily MFS_1 Daro_0405 174 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 71906071 Nonpathogen - hypothetical protein Daro_0431 1 None None None 71908111 Nonpathogen - hypothetical protein Daro_2494 1 None None None 71906765 Common greB transcription elongation factor GreB Daro_1126 184 COG0782 GreA, Transcription elongation factor Transcription 71906782 Common - Histidine kinase, HAMP region:Bacterial chemotaxis sensory transducer Daro_1143 135 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 71907671 Common - Cyclic nucleotide-binding Daro_2043 42 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 71908029 Common - Glycosyl transferase, group 1 Daro_2410 222 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 71906309 Common - 4Fe-4S ferredoxin, iron-sulfur binding Daro_0670 95 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 71907784 Common - Hydrophobe/amphiphile efflux-1 HAE1 Daro_2161 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 71908734 Common aceK bifunctional isocitrate dehydrogenase kinase/phosphatase protein Daro_3121 29 COG4579 COG4579, Isocitrate dehydrogenase kinase/phosphatase Signal transduction mechanisms 71908829 Common - type II and III secretion system protein:NolW-like:Secretin/TonB, short N-terminal Daro_3216 140 COG4796 HofQ, Type II secretory pathway, component HofQ Intracellular trafficking and secretion 71906104 Common - OmpA/MotB Daro_0464 147 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 71905778 Nonpathogen - hypothetical protein Daro_0136 1 None None None 71907492 Common argC N-acetyl-gamma-glutamyl-phosphate reductase Daro_1863 215 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 71909677 Common - Protein of unknown function DUF853, NPT hydrolase putative Daro_4068 78 COG0433 COG0433, Predicted ATPase General function prediction only 71906764 Common - hypothetical protein Daro_1125 8 None None None 71906177 Common - Tyrosine recombinase XerD Daro_0537 230 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 71907309 Common argD bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein Daro_1679 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 71909686 Common - regulatory protein, LysR:LysR, substrate-binding Daro_4077 145 COG0583 LysR, Transcriptional regulator Transcription 71906632 Common - Alpha/beta hydrolase fold:Poly-beta-hydroxybutyrate polymerase, N-terminal Daro_0993 73 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 71908091 Common - Heavy metal sensor kinase Daro_2473 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 71909145 Common - Lytic transglycosylase, catalytic Daro_3533 39 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 71907217 Common - Helix-turn-helix, Fis-type Daro_1585 210 COG4567 COG4567, Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain Signal transduction mechanisms / Transcription 71907500 Common - Acyltransferase 3 Daro_1871 68 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 71908530 Nonpathogen - hypothetical protein Daro_2917 1 None None None 71909498 Common - Conserved hypothetical protein 251 Daro_3887 90 COG1872 COG1872, Uncharacterized conserved protein Function unknown 71906887 Common - LmbE-like protein Daro_1249 33 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 71907398 Common - phosphoenolpyruvate synthase Daro_1768 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 71908452 Common - dihydroorotate dehydrogenase 2 Daro_2839 90 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 71908837 Common - hypothetical protein Daro_3224 3 None None None 71909179 Common - Phosphate regulon transcriptional regulatory protein phoB Daro_3567 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 71906953 Common - Peptidoglycan-binding LysM:Lytic transglycosylase, catalytic Daro_1320 119 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 71905671 Common - probable proline rich signal peptide protein Daro_0029 24 None None None 71907990 Common - ABC transporter related Daro_2371 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 71909670 Common - hypothetical protein Daro_4061 94 COG0628 PerM, Predicted permease General function prediction only 71909191 Common - chemotaxis sensory transducer Daro_3579 127 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 71907156 Common - Carboxymuconolactone decarboxylase Daro_1524 78 COG2128 COG2128, Uncharacterized conserved protein Function unknown 71905727 Common - hypothetical protein Daro_0085 6 None None None 71906562 Common - Heat shock protein Hsp70 Daro_0923 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 71907668 Common - Protein of unknown function DUF1178 Daro_2040 47 COG5319 COG5319, Uncharacterized protein conserved in bacteria Function unknown 71908769 Common - Cytochrome c biogenesis protein, transmembrane region Daro_3156 92 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 71906366 Common - CheW-like protein Daro_0727 130 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 71906639 Common - Helix-turn-helix, Fis-type Daro_1000 178 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 71909287 Common - Thiopurine S-methyltransferase Daro_3675 34 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 71907390 Common - UspA Daro_1760 137 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 71909768 Common - hypothetical protein Daro_4159 75 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 71908425 Common - hypothetical protein Daro_2812 13 None None None 71907493 Common - Patatin Daro_1864 126 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 71907792 Common - hypothetical protein Daro_2170 2 None None None 71907892 Common - Flagellar basal-body rod protein FlgB Daro_2272 86 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 71909407 Common - Monooxygenase component MmoB/DmpM Daro_3795 8 None None None 71909569 Common - Integrase, catalytic region Daro_3959 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 71907300 Common - hypothetical protein Daro_1670 13 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 71908617 Common - ribosome-associated GTPase Daro_3004 164 COG1162 COG1162, Predicted GTPases General function prediction only 71906333 Common - regulatory protein, MarR Daro_0694 30 COG1846 MarR, Transcriptional regulators Transcription 71909273 Common - Nucleotidyl transferase Daro_3661 215 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 71906843 Common - AMP-dependent synthetase and ligase Daro_1204 218 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 71908407 Common - Cytochrome B561, bacterial Daro_2794 87 COG3038 CybB, Cytochrome B561 Energy production and conversion