Gluconobacter oxydans 621H, complete genome NC_006677 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 58038526 Common - Enoyl[acyl-carrier-protein] reductase GOX0036 141 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 58039953 Nonpathogen - hypothetical protein GOX1519 2 None None None 58039376 Common - hypothetical protein GOX0912 133 COG1733 COG1733, Predicted transcriptional regulators Transcription 58039875 Common - Putative DnaJ-like protein GOX1433 56 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 58040163 Common - N-acetylmuramoyl-L-alanine amidase GOX1732 177 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 58040425 Common - Glutamate racemase GOX1997 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 58038537 Common - BolA protein GOX0048 30 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 58040415 Common - hypothetical protein GOX1987 38 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 58038519 Common - hypothetical protein GOX0029 32 None None None 58038590 Common - Carboxypeptidase-related protein GOX0103 37 COG2939 COG2939, Carboxypeptidase C (cathepsin A) Amino acid transport and metabolism 58039371 Common - TonB-dependent outer membrane receptor GOX0907 33 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 58040795 Common - Putative oxidoreductase GOX2371 180 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 58039398 Common - hypothetical protein GOX0934 7 None None None 58039474 Common - hypothetical protein GOX1011 59 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 58039294 Common - hypothetical protein GOX0828 3 None None None 58038616 Common - Transcriptional regulator, AsnC family GOX0130 147 COG1522 Lrp, Transcriptional regulators Transcription 58040545 Common - bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase GOX2117 220 COG4230 COG4230, Delta 1-pyrroline-5-carboxylate dehydrogenase Energy production and conversion 58039945 Nonpathogen - hypothetical protein GOX1510 1 None None None 58038530 Common - hypothetical protein GOX0040 17 COG4731 COG4731, Uncharacterized protein conserved in bacteria Function unknown 58038910 Common - acetyl-CoA carboxylase biotin carboxylase subunit GOX0435 227 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 58040205 Common - Putative ATP-sensitive potassium channel protein GOX1774 18 COG1964 COG1964, Predicted Fe-S oxidoreductases General function prediction only 58040592 Common - Transcriptional regulator GOX2164 30 COG1309 AcrR, Transcriptional regulator Transcription 58038727 Common - 1-deoxy-D-xylulose-5-phosphate synthase GOX0252 224 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 58039716 Common - DNA topoisomerase I GOX1263 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 58039232 Common - Methyl-accepting chemotaxis protein GOX0766 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 58039013 Common - Dipeptidase PepQ GOX0543 204 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 58039154 Common - Putative sugar efflux protein GOX0685 150 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 58039331 Common - Xylitol Dehydrogenase GOX0865 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 58039219 Common - hypothetical protein GOX0750 28 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 58040603 Common - ATP synthase gamma chain GOX2175 52 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 58040555 Common - ABC transporter permease protein GOX2127 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 58040624 Common - N-formylglutamate deformylase GOX2197 57 COG3741 HutG, N-formylglutamate amidohydrolase Amino acid transport and metabolism 58039523 Common - Chromosome partitioning protein ParB GOX1062 186 COG1475 Spo0J, Predicted transcriptional regulators Transcription 58040681 Common - hypothetical protein GOX2255 65 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 58040510 Common - predicted membrane fusion protein of efflux pump GOX2082 151 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 58039539 Common - S-adenosyl-L-homocysteine hydrolase GOX1078 176 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 58039588 Common - hypothetical protein GOX1128 15 None None None 58038926 Common rpsI 30S ribosomal protein S9 GOX0451 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 58040574 Common - hypothetical protein GOX2146 5 None None None 58039871 Common - GTP-binding protein GOX1429 236 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 58040010 Common - ATP-dependent Clp protease ATP-binding subunit ClpA GOX1577 216 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 58040455 Common - hypothetical protein GOX2027 3 None None None 58040116 Common - MotA/TolQ/ExbB proton channel family protein GOX1684 148 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 58039114 Common - Histidine kinase-response regulator hybrid protein GOX0645 201 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 58040065 Common - hypothetical protein GOX1632 94 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 58039578 Common - Trehalose-phosphatase GOX1118 85 COG1877 OtsB, Trehalose-6-phosphatase Carbohydrate transport and metabolism 58039755 Common - Paraquat-inducible protein B GOX1303 64 COG3008 PqiB, Paraquat-inducible protein B General function prediction only 58038837 Common - LSU ribosomal protein L30P GOX0362 141 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 58038512 Common - Membrane-bound lytic murein transglycosylase GOX0021 104 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 58039932 Common - Acyl-CoA dehydrogenase GOX1497 12 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 58040505 Common - Ferric siderophore receptor GOX2077 94 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 58038563 Common tsf elongation factor Ts GOX0074 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 58038547 Nonpathogen - hypothetical protein GOX0058 1 None None None 58040146 Common - Glycerophosphoryl diester phosphodiesterase GOX1714 108 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 58040604 Common - Non-hemolytic phospholipase C GOX2176 33 COG3511 PlcC, Phospholipase C Cell envelope biogenesis, outer membrane 58039598 Common - Putative oxidoreductase GOX1139 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 58039695 Common - hypothetical protein GOX1242 105 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 58039416 Common flgA flagellar basal body P-ring biosynthesis protein FlgA GOX0952 32 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 58040633 Common - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase GOX2206 148 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 58039733 Common - hypothetical protein GOX1280 14 None None None 58039007 Common - Phosphate-binding protein GOX0537 112 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 58039880 Common - hypothetical protein GOX1438 115 COG1285 SapB, Uncharacterized membrane protein Function unknown 58040645 Common - ribose-5-phosphate isomerase B GOX2218 128 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 58039502 Common - Mannose-6-phosphate isomerase GOX1040 42 COG2942 COG2942, N-acyl-D-glucosamine 2-epimerase Carbohydrate transport and metabolism 58039082 Common - Putative sugar kinase protein GOX0612 137 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 58039159 Common - Acriflavin resistance protein B (mulitdrug efflux system) GOX0690 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 58038540 Common - Cobalamin biosynthesis protein CobT GOX0051 41 COG4547 CobT, Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase) Coenzyme metabolism 58038903 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase GOX0428 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 58038873 Common - NAD(FAD)-utilizing dehydrogenase GOX0398 140 COG2081 COG2081, Predicted flavoproteins General function prediction only 58040673 Common - Molybdopterin biosynthesis MoeB protein GOX2247 210 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 58039761 Common - F0F1 ATP synthase subunit alpha GOX1311 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 58038994 Common - TonB-dependent outer membrane receptor GOX0524 23 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 58039361 Common - Putative glycosyltransferase GOX0897 5 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 58038850 Common rplV 50S ribosomal protein L22 GOX0375 216 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 58040492 Nonpathogen - hypothetical protein GOX2064 1 None None None 58038786 Common - NAD(P) transhydrogenase subunit alpha GOX0311 117 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 58038946 Common - hypothetical protein GOX0474 224 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 58038603 Common rpmF 50S ribosomal protein L32 GOX0117 109 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 58038784 Common - DNA primase GOX0309 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 58039725 Common - Putative DNA uptake protein GOX1272 41 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 58040180 Nonpathogen - hypothetical protein GOX1749 1 None None None 58040726 Common - Phosphoribosyformylglycinamidine synthase PurL GOX2301 106 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 58038882 Nonpathogen - hypothetical protein GOX0407 1 None None None 58040083 Common - Cytochrome c-type biogenesis protein CysK GOX1650 133 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 58039845 Nonpathogen - hypothetical protein GOX1401 1 None None None 58038688 Common - TonB-dependent outer membrane receptor GOX0207 83 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 58040189 Common - Sec-independent protein translocase protein TatC GOX1758 202 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 58039138 Common - Copper resistance protein CopA GOX0669 131 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 58040311 Common - hypothetical protein GOX1881 84 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 58040006 Common - Amino acid ABC transporter binding protein and permease protein GOX1573 179 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 58040599 Common - ATP synthase subunit a GOX2171 165 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 58040829 Common - Putative RNA polymerase sigma-E factor (sigma-24) protein 1 GOX2406 161 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 58039702 Common ileS isoleucyl-tRNA synthetase GOX1249 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 58039275 Common - L-asparaginase II GOX0809 46 COG4448 AnsA, L-asparaginase II Amino acid transport and metabolism 58038774 Common - hypothetical protein GOX0299 100 COG0795 COG0795, Predicted permeases General function prediction only 58039935 Nonpathogen - hypothetical protein GOX1500 10 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 58040270 Common - Putative translation initiation inhibitor GOX1839 98 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 58039496 Common - hypothetical protein GOX1033 162 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 58039799 Common - hypothetical protein GOX1355 155 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 58040078 Common - hypothetical protein GOX1645 4 None None None 58039661 Nonpathogen - hypothetical protein GOX1208 1 None None None 58040442 Common - Putative two-component trancriptional regulator GOX2014 198 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 58040344 Common - Cytochrome o ubiquinol oxidase subunit IV GOX1914 42 COG3125 CyoD, Heme/copper-type cytochrome/quinol oxidase, subunit 4 Energy production and conversion 58039975 Nonpathogen - hypothetical protein GOX1541 2 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 58038767 Common - DNA polymerase III subunit chi GOX0292 33 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 58039035 Common - Ubiquinol-cytochrome C reductase iron-sulfur subunit GOX0565 89 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 58039746 Common - amidase GOX1293 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 58040179 Common - Bacterioferritin GOX1748 40 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 58040499 Common - D-Lactate dehydrogenase GOX2071 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 58038953 Common hisH imidazole glycerol phosphate synthase subunit HisH GOX0481 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 58040876 Nonpathogen - hypothetical protein GOX2453 1 None None None 58039558 Common - glycine dehydrogenase GOX1097 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 58039447 Common - pyrroloquinoline quinone biosynthesis protein PqqE GOX0983 147 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 58040535 Common - Putative oxidoreductase GOX2107 45 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 58039625 Nonpathogen - hypothetical protein GOX1172 1 None None None 58040404 Common - hypothetical protein GOX1976 193 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 58040215 Common - hypothetical protein GOX1784 9 None None None 58039131 Common - Cation-transporting ATPase GOX0662 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 58040377 Nonpathogen - hypothetical protein GOX1949 2 None None None 58040670 Nonpathogen - hypothetical protein GOX2244 1 None None None 58038665 Common - Adenosylcobalamin-dependent diol dehydratase gamma subunit GOX0183 127 COG2096 COG2096, Uncharacterized conserved protein Function unknown 58039421 Common - Putative chloride channel protein GOX0957 134 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 58039066 Common rpsA 30S ribosomal protein S1 GOX0596 217 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 58040305 Nonpathogen - hypothetical protein GOX1875 1 None None None 58040651 Common - Transposase (class I) GOX2224 58 None None None 58039541 Common - Divalent cation transporter GOX1080 41 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 58038894 Common - Transposase (class II) GOX0419 43 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 58039906 Common - Transposase GOX1471 68 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 58039869 Common - hypothetical protein GOX1426 40 COG3814 COG3814, Uncharacterized protein conserved in bacteria Function unknown 58039055 Common - Cytochrome c subunit of aldehyde dehydrogenase GOX0585 53 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 58039401 Common - DNA repair protein RadA GOX0937 224 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 58040564 Common - Aminopeptidase GOX2136 53 COG2234 Iap, Predicted aminopeptidases General function prediction only 58038573 Common - ATP-dependent protease La GOX0085 211 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 58038498 Common - D-fructose-6-phosphate amidotransferase GOX0007 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 58040356 Common - ABC transporter ATP-binding protein GOX1926 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 58039963 Common - hypothetical protein GOX1529 25 None None None 58040658 Common - Putative sugar transporter GOX2231 48 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 58039210 Common - hypothetical protein GOX0741 42 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 58038608 Common - Transcriptional regulator GOX0122 43 COG1846 MarR, Transcriptional regulators Transcription 58040767 Common - Putative capsid protein of prophage GOX2343 12 None None None 58039285 Common - Two component response regulator ChvI GOX0819 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 58040015 Common infB translation initiation factor IF-2 GOX1582 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 58038941 Common - Nitrogen assimilation regulatory protein NifR3 GOX0469 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 58038582 Common - NifS-like aminotransferase GOX0095 240 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 58039036 Common - Ubiquinol-cytochrome c reductase cytochrome b subunit GOX0566 146 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 58039451 Nonpathogen - Coenzyme PQQ synthesis protein A (Pyrroloquinoline quinonebiosynthesis protein A) GOX0987 2 None None None 58040057 Common - Nonspecific acid phosphatase precursor GOX1624 31 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 58039853 Nonpathogen - hypothetical protein GOX1410 1 None None None 58040281 Common - putative oxidoreductase GOX1851 197 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 58040827 Common - ABC transporter ATP-binding protein GOX2404 231 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 58040743 Nonpathogen - hypothetical protein GOX2319 1 None None None 58039406 Common - hypothetical protein GOX0942 22 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 58040880 Common - Phage DNA Packaging Protein GOX2457 29 COG5323 COG5323, Uncharacterized conserved protein Function unknown 58039256 Common - Peptidase GOX0790 20 None None None 58039680 Common - hypothetical protein GOX1227 3 None None None 58039736 Common hrcA heat-inducible transcription repressor GOX1283 151 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 58040265 Common - tRNA pseudouridine synthase A GOX1834 237 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 58039047 Common - Transcriptional regulator GOX0577 126 COG1609 PurR, Transcriptional regulators Transcription 58038755 Common - Hydroxyacylglutathione hydrolase GOX0280 165 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 58039627 Common - Purine-cytosine permease GOX1174 44 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 58039783 Common - hypothetical protein GOX1339 11 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 58038751 Common - 1-Acyl-sn-glycerol-3-phosphate acyltransferase GOX0276 185 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 58038761 Common - hypothetical protein GOX0286 92 COG3261 HycE, Ni,Fe-hydrogenase III large subunit Energy production and conversion 58038506 Common - Sec-independent protein translocase protein TatD GOX0015 236 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 161898747 Common - DNA gyrase subunit A GOX0887 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 58038801 Common - hypothetical protein GOX0326 36 COG5470 COG5470, Uncharacterized conserved protein Function unknown 58039020 Common - hypothetical protein GOX0550 53 COG0754 Gsp, Glutathionylspermidine synthase Amino acid transport and metabolism 58039823 Nonpathogen - hypothetical protein GOX1379 1 None None None 58040406 Common - hypothetical protein GOX1978 23 COG1633 COG1633, Uncharacterized conserved protein Function unknown 58039458 Common - Acid phosphatase GOX0994 34 COG3511 PlcC, Phospholipase C Cell envelope biogenesis, outer membrane 58039978 Common - ABC transporter permease protein GOX1544 67 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 58039226 Common - Porin GOX0758 17 COG3659 OprB, Carbohydrate-selective porin Cell envelope biogenesis, outer membrane 58039188 Common - adenosylmethionine--8-amino-7-oxononanoate transaminase GOX0719 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 58039104 Nonpathogen - hypothetical protein GOX0635 1 COG5373 COG5373, Predicted membrane protein Function unknown 58039257 Nonpathogen - 5,10-Methylenetetrahydrofolate reductase GOX0791 8 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 58038593 Common rpmB 50S ribosomal protein L28 GOX0106 149 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 58040803 Nonpathogen - hypothetical protein GOX2379 1 None None None 58038917 Nonpathogen - hypothetical protein GOX0442 1 None None None 58039250 Common - Multidrug resistance protein A GOX0784 144 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 58038613 Common - Chemotaxis MotB protein GOX0127 92 COG1360 MotB, Flagellar motor protein Cell motility and secretion 58040297 Common - Putative processing protease protein GOX1867 202 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 58040582 Common - hypothetical protein GOX2154 23 None None None 58038855 Common rplC 50S ribosomal protein L3 GOX0380 221 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 58040911 Common valS valyl-tRNA synthetase GOX2489 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 58039892 Common - Cell division protein FtsY-like protein GOX1451 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 58040754 Nonpathogen - hypothetical protein GOX2330 1 None None None 58039184 Common - Probable secretion ATP-binding protein GOX0715 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 58040227 Common - TonB-dependent outer membrane receptor GOX1796 28 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 58039811 Common - hypothetical protein GOX1367 76 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 58040102 Common - IspD GOX1669 195 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 58038721 Nonpathogen - hypothetical protein GOX0246 5 None None None 58038996 Common - Sulfate permease GOX0526 158 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 58039381 Common - hypothetical protein GOX0917 79 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 58040413 Common - 3-Deoxy-D-manno-octulosonic-acid transferase GOX1985 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 58040503 Common - hypothetical protein GOX2075 3 None None None 58039023 Common - hypothetical protein GOX0553 11 None None None 58040480 Common - hypothetical protein GOX2052 41 COG0795 COG0795, Predicted permeases General function prediction only 58039635 Common - Putative glucokinase GOX1182 143 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 58039194 Common - glucosyltransferase MdoH GOX0725 54 COG2943 MdoH, Membrane glycosyltransferase Cell envelope biogenesis, outer membrane 58040860 Nonpathogen - hypothetical protein GOX2437 1 COG3941 COG3941, Mu-like prophage protein General function prediction only 58040665 Common - hypothetical protein GOX2239 126 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 58040136 Common - bifunctional transaldolase/phosoglucose isomerase GOX1704 156 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 58040919 Common - Deoxyuridine 5'-triphosphate nucleotidohydrolase GOX2497 181 COG0756 Dut, dUTPase Nucleotide transport and metabolism 58040407 Common - Outer-membrane lipoprotein carrier protein GOX1979 37 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 58038799 Common - Transcription elongation factor GOX0324 204 COG0782 GreA, Transcription elongation factor Transcription 58040662 Nonpathogen - hypothetical protein GOX2236 1 None None None 58040774 Common - Phage-related tail protein GOX2350 17 None None None 58040000 Common - DedA family protein GOX1567 53 COG1238 COG1238, Predicted membrane protein Function unknown 58040735 Common - Serine hydroxymethyl transferase GOX2310 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 58040288 Nonpathogen - hypothetical protein GOX1858 1 None None None 58040509 Common - Putative transmembrane protein GOX2081 9 COG1289 COG1289, Predicted membrane protein Function unknown 58040042 Nonpathogen - hypothetical protein GOX1609 1 None None None 58039647 Common - Transposase GOX1194 43 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 58040048 Common - Putative oxidoreductase GOX1615 200 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 58039498 Common - hypothetical protein GOX1035 94 COG1981 COG1981, Predicted membrane protein Function unknown 58040772 Common - Putative phage tail tube protein GOX2348 3 None None None 58040765 Nonpathogen - hypothetical protein GOX2341 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 58038981 Common - hypothetical protein GOX0511 15 None None None 58040713 Common - Indole-3-glycerol phosphate synthase GOX2288 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 58039780 Common - Isocitrate dehydrogenase [NADP] GOX1336 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 58038730 Common - argininosuccinate synthase GOX0255 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 58039245 Common - Two component response regulator GOX0779 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 58039340 Nonpathogen - AtsE protein GOX0875 5 COG5622 COG5622, Protein required for attachment to host cells Cell motility and secretion 58040388 Common - Dephospho-CoA kinase GOX1960 202 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 58038685 Common - hypothetical protein GOX0204 159 COG3754 RgpF, Lipopolysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 58040347 Common - ATP-dependent DNA helicase GOX1917 59 COG4581 COG4581, Superfamily II RNA helicase DNA replication, recombination, and repair 58039283 Nonpathogen - hypothetical protein GOX0817 1 None None None 58039320 Common - D-Sorbitol dehydrogenase subunit SldA GOX0854 58 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 58040038 Common mtnA methylthioribose-1-phosphate isomerase GOX1605 130 COG0182 COG0182, Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 58040865 Nonpathogen - hypothetical protein GOX2442 2 None None None 58040527 Common - Transposase (IS12528) GOX2099 64 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 58040904 Nonpathogen - hypothetical protein GOX2481 1 None None None 58040335 Common lysK lysyl-tRNA synthetase GOX1905 77 COG1384 LysS, Lysyl-tRNA synthetase (class I) Translation, ribosomal structure and biogenesis 58040614 Common - Ribulokinase GOX2186 171 COG1069 AraB, Ribulose kinase Energy production and conversion 58039654 Common - tryptophan synthase subunit beta GOX1201 227 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 58038555 Common - Competence protein ComM GOX0066 189 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 58038886 Common - hypothetical protein GOX0411 8 COG5468 COG5468, Predicted secreted (periplasmic) protein Function unknown 58040477 Nonpathogen - hypothetical protein GOX2049 24 COG2266 COG2266, GTP:adenosylcobinamide-phosphate guanylyltransferase Coenzyme metabolism 58039173 Common - Phosphate transport ATP-binding protein PstB GOX0704 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 58040616 Common - Gluconate permease GOX2188 79 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 58038822 Common - hypothetical protein GOX0347 9 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 58039163 Common - hypothetical protein GOX0694 31 COG3334 COG3334, Uncharacterized conserved protein Function unknown 58038670 Common - Oligoendopeptidase F GOX0188 66 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 58039324 Common - Chaperone protein DnaJ GOX0858 234 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 58038742 Nonpathogen - hypothetical protein GOX0267 3 None None None 58039050 Common - Beta-N-acetylhexosaminidase GOX0580 58 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 58039090 Common - Chemotactic signal-response protein CheL GOX0620 11 COG3951 COG3951, Rod binding protein Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 58040086 Common - hypothetical protein GOX1653 94 COG2947 COG2947, Uncharacterized conserved protein Function unknown 58040647 Common - Ribose ABC transporter, ATP-binding protein GOX2220 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 58039316 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase GOX0850 211 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 58040622 Nonpathogen - hypothetical protein GOX2194 1 None None None 58039629 Common - hypothetical protein GOX1176 127 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 58040017 Common truB tRNA pseudouridine synthase B GOX1584 244 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 58039149 Common - Thiopurine S-methyltransferase GOX0680 31 None None None 58039311 Nonpathogen - hypothetical protein GOX0845 1 None None None 58040152 Common - Transposase (class V) GOX1720 39 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 58040352 Common - Pleiotropic regulatory protein GOX1922 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 58040885 Common - Transcriptional regulator GOX2462 51 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 58039244 Common - Two component sensor histidine kinase GOX0778 211 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 58039687 Nonpathogen - hypothetical protein GOX1234 1 None None None 58039973 Common - Putative acetyltransferase GOX1539 179 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 58040793 Common - Na+/H+ antiporter GOX2369 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 58039094 Common - Ribonuclease D GOX0625 124 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 58039943 Common - hypothetical protein GOX1508 108 COG3177 COG3177, Uncharacterized conserved protein Function unknown 58040814 Common - DNA repair protein RadC GOX2391 49 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 58040898 Nonpathogen - hypothetical protein GOX2475 1 None None None 58039480 Common - TonB-dependent outer membrane receptor GOX1017 47 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 58040196 Common - hypothetical protein GOX1765 49 COG1289 COG1289, Predicted membrane protein Function unknown 58039437 Common - Outer membrane channel lipoprotein GOX0973 72 COG3047 OmpW, Outer membrane protein W Cell envelope biogenesis, outer membrane 58039396 Nonpathogen - hypothetical protein GOX0932 1 None None None 58040891 Nonpathogen - hypothetical protein GOX2468 1 None None None 58039122 Common - Xanthine dehydrogenase XdhB protein GOX0653 107 COG4631 XdhB, Xanthine dehydrogenase, molybdopterin-binding subunit B Nucleotide transport and metabolism 58039303 Common - Putative drug transport transmembrane protein GOX0837 193 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 58039333 Common - SAM-dependent methyltransferase GOX0867 133 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 58040797 Common - Ring-hydroxylating dioxygenase GOX2373 75 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 58039981 Common - hypothetical protein GOX1548 3 COG3577 COG3577, Predicted aspartyl protease General function prediction only 58040753 Nonpathogen - hypothetical protein GOX2329 1 None None None 58039430 Common - hypothetical protein GOX0966 15 None None None 58040629 Common - Putative acetyltransferase GOX2202 69 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 58040091 Common - hypothetical protein GOX1658 6 None None None 58038677 Common - tRNA (Guanine-N(1)-)-methyltransferase GOX0195 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 58038970 Common - Putative NAD-dependent aldehyde dehydrogenase GOX0499 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 58038827 Common - hypothetical protein GOX0352 4 None None None 58038938 Common - Nitrogen assimilation regulatory protein NtrX GOX0466 221 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 58039986 Common - Chemotaxis protein CheW GOX1553 129 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 58040213 Common mtnK methylthioribose kinase GOX1782 30 COG4857 COG4857, Predicted kinase General function prediction only 58040694 Common - hypothetical protein GOX2269 43 COG3786 COG3786, Uncharacterized protein conserved in bacteria Function unknown 58038709 Common - Lysine 2,3-aminomutase GOX0234 125 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 58040256 Common - LSU ribosomal protein L34P GOX1825 184 None None None 58040432 Common - Putative thiol:disulfide interchange protein GOX2004 52 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 58038962 Common - Transposase (class II) GOX0491 44 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 58039065 Common - Putative glycosyltransferase GOX0595 27 COG4641 COG4641, Uncharacterized protein conserved in bacteria Function unknown 58039145 Common - Iron-regulated sigma factor/transcriptional regulator GOX0676 36 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 58038933 Common - Sulfate permease GOX0459 161 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 58040249 Common - Outer membrane protein GOX1818 157 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 58038977 Common pgk phosphoglycerate kinase GOX0507 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 58040576 Common - Transposase (class I) GOX2148 57 None None None 58040497 Common - Transcriptional regulator GOX2069 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 58039600 Common - LSU ribosomal protein L25P GOX1141 166 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 58039930 Common - Oxidoreductase, iron-sulphur binding subunit GOX1495 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 58039530 Common - O6-methylguanine-DNA methyltransferase GOX1069 130 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 58040561 Nonpathogen - hypothetical protein GOX2133 2 None None None 58039077 Common - D-alanyl-D-alanine carboxypeptidase GOX0607 153 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 58039894 Common - Diaminopimelate epimerase GOX1453 200 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 58040121 Common - hypothetical protein GOX1689 23 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 58040060 Common - Cation efflux system protein GOX1627 197 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 58040548 Common - Dipeptide ABC transport system ATP-binding protein DppD GOX2120 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 58040836 Common - hypothetical protein GOX2413 9 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 58040398 Common engA GTP-binding protein EngA GOX1970 236 COG1160 COG1160, Predicted GTPases General function prediction only 58040114 Common ruvB Holliday junction DNA helicase B GOX1682 232 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 58038565 Common dnaE DNA polymerase III subunit alpha GOX0076 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 58038510 Common - D-alanyl-D-alanine carboxypeptidase GOX0019 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 58040882 Nonpathogen - hypothetical protein GOX2459 1 None None None 58039124 Common - Oligopeptide ABC transporter ATP-binding protein OppF GOX0655 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 58039088 Common - Hemolysin-related protein GOX0618 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 58038901 Nonpathogen - hypothetical protein GOX0426 1 None None None 58038598 Common - Putative permease GOX0111 87 COG0628 PerM, Predicted permease General function prediction only 58039576 Common - hypothetical protein GOX1116 8 None None None 58040724 Common - Adenylosuccinate lyase GOX2299 241 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 58039367 Common - hypothetical protein GOX0903 50 COG3195 COG3195, Uncharacterized protein conserved in bacteria Function unknown 58038624 Common rplU 50S ribosomal protein L21 GOX0139 138 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 58039266 Common - Possible amidotransferase GOX0800 120 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 58039596 Common - Probable lipopolysaccharide modification acyltransferase GOX1137 45 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 58040144 Common - Aldehyde dehydrogenase GOX1712 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 58039659 Common - replicative DNA helicase GOX1206 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 58039500 Common - Uroporphyrinogen decarboxylase GOX1037 177 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 58038545 Common - ATP-dependent DNA helicase RecG GOX0056 213 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 58039363 Common - Transposase (class I) GOX0899 58 None None None 58040566 Common - hypothetical protein GOX2138 86 COG3384 COG3384, Uncharacterized conserved protein Function unknown 58038641 Common - UDP-N-acetylmuramoylalanine--D-glutamate ligase GOX0156 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 58038964 Common - hypothetical protein GOX0493 19 COG3410 COG3410, Uncharacterized conserved protein Function unknown 58039212 Common - Ammonium transporter AmtB GOX0743 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 58039958 Common - Flagellar biosynthetic protein FliR GOX1524 59 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 58040856 Common - Phage-related baseplate assembly protein GOX2433 8 COG4540 gpV, Phage P2 baseplate assembly protein gpV General function prediction only 58039528 Common - Alcohol dehydrogenase cytochrome c subunit precursor GOX1067 71 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 58038697 Common - N-methylhydantoinase A GOX0216 119 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 58040878 Common - Putative phage-related protein GOX2455 2 None None None 58038919 Common - Bifunctional molybdenum cofactor biosynthesis protein (Molybdopterin-guanine dinucleotide biosynthesis protein A and MoaD) GOX0444 101 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 58038532 Common - Competence protein F GOX0042 168 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 58039690 Common - Acetylornithine aminotransferase GOX1237 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 58039818 Common - DNA topoisomerase I GOX1374 44 COG3569 COG3569, Topoisomerase IB DNA replication, recombination, and repair 58038829 Common - Putative sugar/polyol transporter GOX0354 12 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 58040543 Common - hypothetical protein GOX2115 48 COG1289 COG1289, Predicted membrane protein Function unknown 58039714 Common - hypothetical protein GOX1261 32 COG5447 COG5447, Uncharacterized conserved protein Function unknown 58038982 Common - Amino acid transport protein GOX0512 76 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 58039740 Common - Biopolymer transport ExbB protein GOX1287 137 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 58038804 Common - Stress response protein CsbD GOX0329 40 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 58039118 Common - Sugar-proton symporter GOX0649 163 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 58039873 Common - hypothetical protein GOX1431 11 COG4129 COG4129, Predicted membrane protein Function unknown 58038912 Common - 3-dehydroquinate dehydratase GOX0437 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 58040366 Common - polyphosphate kinase GOX1936 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 58038876 Common - Cell division inhibitor MinD GOX0401 146 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 58039641 Common - Outer membrane receptor protein GOX1188 27 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 58040327 Common - 5'-methylthioadenosine phosphorylase GOX1897 144 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 58039609 Common - hypothetical protein GOX1150 167 COG1576 COG1576, Uncharacterized conserved protein Function unknown 58039877 Common - Iron-sulfur cluster-binding protein GOX1435 133 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 58039611 Common - hypothetical protein GOX1152 104 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 58039551 Common - S-adenosylmethionine decarboxylase proenzyme GOX1090 72 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 58040869 Nonpathogen - hypothetical protein GOX2446 1 None None None 58040109 Common - Peptidyl-prolyl cis-trans isomerase precursor GOX1677 154 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 58039527 Common trmE tRNA modification GTPase TrmE GOX1066 221 COG0486 ThdF, Predicted GTPase General function prediction only 58040626 Common - probable myosin-crossreactive antigen GOX2199 25 COG4716 COG4716, Myosin-crossreactive antigen Function unknown 58040391 Common - Lipopolysaccharide core biosynthesis glycosyl transferase LpsE GOX1963 172 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 58038633 Common - hypothetical protein GOX0148 3 None None None 58039521 Common - hypothetical protein GOX1059 31 COG5519 COG5519, Superfamily II helicase and inactivated derivatives DNA replication, recombination, and repair 58040638 Common - hypothetical protein GOX2211 8 COG4099 COG4099, Predicted peptidase General function prediction only 58038524 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase GOX0034 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 58039786 Common - Alpha-glucosidase GOX1342 81 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 58039922 Common - UDP-glucose 4-epimerase GOX1487 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 58039999 Common - Transposase (class IV) GOX1566 57 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 58038920 Common moaC molybdenum cofactor biosynthesis protein C GOX0445 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 58038951 Common - Imidazoleglycerol-phosphate dehydratase GOX0479 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 58038868 Common - Putative transport transmembrane protein GOX0393 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 58039668 Nonpathogen - hypothetical protein GOX1215 2 None None None 58040584 Common - Putative ABC transporter permease protein GOX2156 14 COG4587 COG4587, ABC-type uncharacterized transport system, permease component General function prediction only 58038579 Common - ATP-dependent RNA helicase GOX0092 236 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 58039449 Common - pyrroloquinoline quinone biosynthesis protein PqqC GOX0985 41 COG5424 COG5424, Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C Coenzyme metabolism 58038769 Nonpathogen - hypothetical protein GOX0294 1 None None None 58039867 Nonpathogen - hypothetical protein GOX1424 2 None None None 58040500 Nonpathogen - hypothetical protein GOX2072 1 None None None 58039843 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase GOX1399 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 58039831 Common - Transposase (fragment) GOX1387 23 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 58040239 Common acpS 4'-phosphopantetheinyl transferase GOX1808 123 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 58039068 Common - 3-Phosphoshikimate 1-carboxyvinyltransferase GOX0598 231 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 58038976 Common - RNA polymerase factor sigma-32 GOX0506 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 58038553 Common - Inositol-1-monophosphatase GOX0064 185 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 58040217 Common alaS alanyl-tRNA synthetase GOX1786 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 58040206 Common - SpoU rRNA methylase family protein GOX1775 154 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 58039908 Common - N-acetylglucosamine-6-phosphate deacetylase GOX1473 119 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 58039056 Common - Membrane-bound aldehyde dehydrogenase, small subunit GOX0586 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 58038663 Common - Oligopeptide transporter GOX0181 41 COG1297 COG1297, Predicted membrane protein Function unknown 58039296 Common - Two component response regulator GOX0830 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 58038956 Common - Phosphoribosyl-ATP pyrophosphatase GOX0484 174 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 58039491 Common - hypothetical protein GOX1028 147 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 58039423 Nonpathogen - hypothetical protein GOX0959 1 None None None 58040013 Common nusA transcription elongation factor NusA GOX1580 219 COG0195 NusA, Transcription elongation factor Transcription 58038606 Common - Osmolarity sensor protein envZ GOX0120 178 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 58039514 Common - Glucose-1-phosphate thymidylyltransferase, C-terminus GOX1052 153 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 58039198 Nonpathogen - hypothetical protein GOX0729 2 None None None 58040023 Common - Transposase (class I) GOX1590 57 None None None 58039441 Nonpathogen - hypothetical protein GOX0977 1 None None None 58040427 Common - Citrate synthase GOX1999 193 COG0372 GltA, Citrate synthase Energy production and conversion 58039543 Nonpathogen - hypothetical protein GOX1082 1 None None None 58039278 Common - Phosphoenolpyruvate-protein phosphotransferase GOX0812 234 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 58038958 Common - DNA integration/recombination/invertion protein GOX0487 45 None None None 58039857 Common - Chaperone protein DnaJ GOX1414 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 58040119 Common tolB translocation protein TolB GOX1687 152 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 58040178 Common aspS aspartyl-tRNA synthetase GOX1747 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 58038504 Common - hypothetical protein GOX0013 14 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 58038601 Common - 3-Oxoacyl-[acyl-carrier-protein] synthase III GOX0115 226 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 58039426 Common - hypothetical protein GOX0962 12 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 58039965 Common fliP flagellar biosynthesis protein FliP GOX1531 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 58039700 Common - hypothetical protein GOX1247 62 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 58040081 Common - Cytochrome c-type biogenesis protein CycL precursor GOX1648 92 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 58040490 Common - hypothetical protein GOX2062 19 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 58039463 Common - Putative glycosyltransferase GOX0999 5 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 58040553 Common - hypothetical protein GOX2125 58 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 58039886 Common - N-acetyl-gamma-glutamyl-phosphate reductase GOX1444 211 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 58039100 Common - Thioredoxin reductase GOX0631 220 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 58040679 Common - Putative oxidoreductase GOX2253 216 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 58040462 Common - Metalloprotease GOX2034 63 COG3590 PepO, Predicted metalloendopeptidase Posttranslational modification, protein turnover, chaperones 58039585 Common - Glycosyltransferase GOX1125 75 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 58039116 Common - hypothetical protein GOX0647 53 COG1289 COG1289, Predicted membrane protein Function unknown 58040434 Common - hypothetical protein GOX2006 216 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 58038848 Common rplP 50S ribosomal protein L16 GOX0373 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 58040055 Common - Transposase GOX1622 146 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 58038880 Common - TonB-dependent outer membrane receptor GOX0405 86 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 58040656 Common - Thiamin biosynthesis protein ThiF GOX2229 191 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 58040354 Common - Putative permease GOX1924 160 COG0628 PerM, Predicted permease General function prediction only 58038782 Common - Putative acetyltransferase GOX0307 27 None None None 58039727 Common - Endonuclease III GOX1274 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 58038892 Common - Putative 2-hydroxyacid dehydrogenase GOX0417 230 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 58039203 Nonpathogen - hypothetical protein GOX0734 1 None None None 58040154 Common - hypothetical protein GOX1723 75 COG2267 PldB, Lysophospholipase Lipid metabolism 58039663 Nonpathogen - hypothetical protein GOX1210 1 None None None 58039899 Common - Putative oxidoreductase GOX1458 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 58040440 Common - hypothetical protein GOX2012 89 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 58040331 Common groES co-chaperonin GroES GOX1901 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 58040187 Common - hypothetical protein GOX1756 139 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 58038841 Common rpsH 30S ribosomal protein S8 GOX0366 242 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 58039825 Common - Gluconolactonase GOX1381 58 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 58039537 Common - Periplasmic phosphoanhydride phosphohydrolase GOX1076 16 None None None 58040186 Common - hypothetical protein GOX1755 35 COG1354 COG1354, Uncharacterized conserved protein Function unknown 58038776 Common - Peptidyl-prolyl cis-trans isomerase GOX0301 96 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 58040231 Common - Superoxide dismutase [Fe] GOX1800 207 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 58040831 Common - Putative sensory transduction histidine kinase GOX2408 97 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 58040342 Common - Cytochrome o ubiquinol oxidase subunit I GOX1912 168 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 58038686 Common - Transposase (class I) GOX0205 57 None None None 58039033 Common - hypothetical protein GOX0563 22 COG1309 AcrR, Transcriptional regulator Transcription 58040272 Nonpathogen - hypothetical protein GOX1841 2 None None None 58040383 Common - argininosuccinate lyase GOX1955 229 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 58038810 Common - ABC transporter ATP-binding protein GOX0335 245 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 58040372 Common - hypothetical protein GOX1942 3 None None None 58040225 Common - Bifunctional acetyltransferase GOX1794 164 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 58040667 Common - pyridoxal phosphate biosynthetic protein PdxJ GOX2241 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 58040049 Common - hypothetical protein GOX1616 4 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 58038732 Common - Thymidine kinase GOX0257 44 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 58039213 Common - Nitrogen regulatory protein P-II, GlnK GOX0744 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 58040131 Nonpathogen - hypothetical protein GOX1699 2 None None None 58038823 Common - HlyD family secretion protein GOX0348 150 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 58039465 Common - ATP-dependent RNA helicase GOX1001 240 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 58038834 Common - Adenylate kinase GOX0359 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 58040379 Nonpathogen - hypothetical protein GOX1951 2 None None None 58039182 Common - hypothetical protein GOX0713 106 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 58040642 Common - Glycerol-3-phosphate dehydrogenase GOX2215 149 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 58040887 Nonpathogen - hypothetical protein GOX2464 1 None None None 58039565 Common - TldD protein GOX1104 170 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 58039637 Common - ABC transporter sugar-binding protein GOX1184 61 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 58040913 Common - dihydroxy-acid dehydratase GOX2491 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 58039927 Common - Transposase (class III) GOX1492 154 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 58039615 Common - Histidine utilization repressor GOX1162 132 COG2188 PhnF, Transcriptional regulators Transcription 58039383 Common - Putative efflux protein GOX0919 217 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 58040063 Common - Putative oxidoreductase GOX1630 81 COG2509 COG2509, Uncharacterized FAD-dependent dehydrogenases General function prediction only 58038924 Common - hypothetical protein GOX0449 95 COG2068 COG2068, Uncharacterized MobA-related protein General function prediction only 58039058 Common - hypothetical protein GOX0588 3 None None None 58040233 Common - putative sulfite oxidase subunit YedY GOX1802 124 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 58039074 Common - DNA polymerase III subunits gamma and tau GOX0604 246 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 58039833 Common - Transposase (class II) GOX1389 43 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 58039821 Common - Na+/H+ Antiporter NhaA GOX1377 134 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 58040590 Common - Transcriptional regulator GOX2162 191 COG0583 LysR, Transcriptional regulator Transcription 58040482 Nonpathogen - hypothetical protein GOX2054 11 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 58040906 Nonpathogen - hypothetical protein GOX2483 1 None None None 58040138 Common - Putative hydrolase of the HAD superfamily GOX1706 134 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 58039689 Common - Ornithine carbamoyltransferase GOX1236 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 58040044 Common - GDP-6-deoxy-D-lyxo-4-hexulose reductase GOX1611 202 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 58038735 Common - Lipid-A-disaccharide synthase GOX0260 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 58040400 Common - Putative transport protein GOX1972 203 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 58039238 Common - Transcriptional regulator GOX0772 29 COG4957 COG4957, Predicted transcriptional regulator Transcription 58038725 Common - Exodeoxyribonuclease VII small subunit GOX0250 130 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 58039403 Common - Glycosyltransferase GOX0939 65 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 58040176 Nonpathogen - hypothetical protein GOX1745 1 COG3416 COG3416, Uncharacterized protein conserved in bacteria Function unknown 58039763 Common - F0F1 ATP synthase subunit beta GOX1313 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 58039656 Common - hypothetical protein GOX1203 25 COG3247 HdeD, Uncharacterized conserved protein Function unknown 58039476 Common - Ferrichrome ABC transporter permease protein GOX1013 184 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 58038580 Common - tRNA (Uracil-5-) -methyltransferase GOX0093 191 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 58038817 Common - hypothetical protein GOX0342 21 None None None 58039855 Common - Outer membrane channel protein GOX1412 114 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 58039318 Common - Permease GOX0852 81 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 58039175 Common - Phosphate transport system permease protein PstC GOX0706 226 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 58038753 Common - Cytochrome d ubiquinol oxidase subunit I GOX0278 164 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 58039356 Common uvrA excinuclease ABC subunit A GOX0892 238 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 58040522 Common - Sorbitol dehydrogenase cytochrome c subunit GOX2094 60 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 58040474 Common - hypothetical protein GOX2046 28 COG5321 COG5321, Uncharacterized protein conserved in bacteria Function unknown 58039252 Common - hypothetical protein GOX0786 55 COG4277 COG4277, Predicted DNA-binding protein with the Helix-hairpin-helix motif General function prediction only 58039224 Nonpathogen - Alcohol dehydrogenase 15 kDa subunit GOX0756 1 None None None 58040825 Common secD preprotein translocase subunit SecD GOX2402 209 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 58040597 Common - ATP synthase subunit AtpI GOX2169 4 None None None 58039801 Common - Putative electron transport protein GOX1357 94 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 58039102 Nonpathogen - hypothetical protein GOX0633 4 None None None 58040295 Common - Putative transmembrane protein GOX1865 23 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 58039186 Common - Transcriptional regluator LysR family GOX0717 149 COG0583 LysR, Transcriptional regulator Transcription 58039912 Common - Capsule polysaccharide biosynthesis protein GOX1477 26 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 58040263 Common - succinyl-diaminopimelate desuccinylase GOX1832 212 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 58040712 Common - Anthranilate phosphoribosyltransferase GOX2287 220 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 58040741 Common - hypothetical protein GOX2316 5 None None None 58040786 Common - hypothetical protein GOX2362 4 None None None 58040801 Common - Transcriptional regulator GOX2377 57 COG1309 AcrR, Transcriptional regulator Transcription 58040449 Common - Phosphoribosyl-AMP cyclohydrolase GOX2021 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 58039748 Common - Gamma-glutamyltranspeptidase GOX1295 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 58039682 Common - hypothetical protein GOX1229 3 None None None 58040368 Common - CDP-diacylglycerol pyrophosphatase GOX1938 19 COG2134 Cdh, CDP-diacylglycerol pyrophosphatase Lipid metabolism 58040128 Nonpathogen - hypothetical protein GOX1696 1 None None None 58038984 Common - NifS-like protein GOX0514 207 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 58039147 Common - TonB-dependent outer membrane receptor GOX0678 37 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 58040098 Common - Ribosomal large subunit pseudouridine synthase C GOX1665 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 58039092 Common - DnaK suppressor protein GOX0622 153 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 58038595 Common - ABC transporter ATP-binding protein GOX0108 151 COG5265 ATM1, ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components Posttranslational modification, protein turnover, chaperones 58040601 Common - ATP synthase subunit b GOX2173 15 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 58040807 Common - Glutamyl-tRNA(Gln) amidotransferase subunit C GOX2384 148 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 58040409 Common - hypothetical protein GOX1981 29 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 58039988 Common - Chemotaxis protein CheB GOX1555 152 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 58040800 Common - Putative aldehyde dehydrogenase GOX2376 218 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 58039613 Common - hypothetical protein GOX1154 83 COG1430 COG1430, Uncharacterized conserved protein Function unknown 58040893 Nonpathogen - hypothetical protein GOX2470 1 None None None 58039365 Common - Xanthine/uracil permease GOX0901 129 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 58040198 Nonpathogen - hypothetical protein GOX1767 1 None None None 58039435 Common - Cation efflux system protein CzcA GOX0971 178 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 58039471 Nonpathogen - hypothetical protein GOX1008 1 COG4803 COG4803, Predicted membrane protein Function unknown 58040612 Common - Probable mannitol/sorbitol ABC transporter permease protein GOX2184 151 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 58040810 Common - Xaa-Pro aminopeptidase GOX2387 187 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 58040692 Common - Putative acetyltransferase GOX2267 30 COG0456 RimI, Acetyltransferases General function prediction only 58039808 Common - Tyrosyl-tRNA synthetase GOX1364 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 58039268 Common - hypothetical protein GOX0802 198 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 58039305 Common - hypothetical protein GOX0839 71 COG1695 COG1695, Predicted transcriptional regulators Transcription 58040286 Common - hypothetical protein GOX1856 4 None None None 58039206 Common - hypothetical protein GOX0737 3 None None None 58039771 Common - hypothetical protein GOX1327 21 COG3431 COG3431, Predicted membrane protein Function unknown 58038993 Common - Sugar transporter transmembrane protein GOX0523 119 None None None 58039342 Common murQ N-acetylmuramic acid-6-phosphate etherase GOX0877 84 COG2103 COG2103, Predicted sugar phosphate isomerase General function prediction only 58038757 Common - phosphatidylserine decarboxylase GOX0282 93 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 58038707 Common - Lysyl-tRNA synthetase GOX0232 200 COG2269 COG2269, Truncated, possibly inactive, lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 58039049 Common - Phosphoglycolate phosphatase GOX0579 171 COG0546 Gph, Predicted phosphatases General function prediction only 58039373 Common - Thiol:disulfide interchange protein DsbD GOX0909 132 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 58039335 Common - Electron transfer flavoprotein beta-subunit GOX0869 153 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 58039418 Common - Flagellar basal-body rod protein FlgF GOX0954 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 58040707 Common - CTP synthetase GOX2282 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 58039247 Common - Outer membrane channel protein GOX0781 108 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 58039143 Common - Ferrous iron transport protein B (FeoB) GOX0674 153 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 58040350 Common - Undecaprenyl-phosphate alpha N-acetylglucosaminyltransferase GOX1920 163 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 58040719 Common - hypothetical protein GOX2294 102 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 58038654 Common - Hypothetical membrane-spanning protein GOX0169 218 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 58040688 Common - Ribosomal RNA large subunit methyltransferase J GOX2262 139 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 58040034 Common - cysteine synthase A GOX1601 225 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 58039650 Nonpathogen - hypothetical protein GOX1197 4 None None None 58040036 Common - hypothetical protein GOX1603 9 COG4322 COG4322, Uncharacterized protein conserved in bacteria Function unknown 58039996 Common - hypothetical protein GOX1563 146 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 58039754 Common - Paraquat-inducible protein A GOX1302 55 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 58039552 Common - spermidine synthase GOX1091 129 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 58040340 Common - hypothetical protein GOX1910 111 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 58039281 Common - hypothetical protein GOX0815 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 58040165 Common - hypothetical protein GOX1734 44 COG0730 COG0730, Predicted permeases General function prediction only 58039674 Nonpathogen - Phage-recombinase-like protein GOX1221 1 None None None 58039410 Common - Putative oxidoreductase GOX0946 88 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 58038657 Common - xanthine-guanine phosphoribosyltransferase GOX0174 82 COG2236 COG2236, Predicted phosphoribosyltransferases General function prediction only 58038683 Common - MetW protein, involved in methionine biosynthesis GOX0202 60 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 58040529 Common - Nuclease S1 GOX2101 21 None None None 58040386 Common - hypothetical protein GOX1958 38 COG3931 COG3931, Predicted N-formylglutamate amidohydrolase Amino acid transport and metabolism 58039889 Common - adenylosuccinate synthetase GOX1448 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 58040867 Common - hypothetical protein GOX2444 15 COG1787 COG1787, Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes Defense mechanisms 58040649 Common - Dihydroxyacetone kinase GOX2222 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 58039015 Common - Putative outer membrane receptor for iron transport GOX0545 38 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 58039738 Common - Bacterial Peptide Chain Release Factor 2 (RF-2) GOX1285 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 58038835 Common secY preprotein translocase subunit SecY GOX0360 230 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 58038852 Common rplB 50S ribosomal protein L2 GOX0377 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 58040325 Common - hypothetical protein GOX1895 4 None None None 58039242 Common - hypothetical protein GOX0776 58 COG0778 NfnB, Nitroreductase Energy production and conversion 58039518 Nonpathogen - hypothetical protein GOX1056 1 None None None 58039165 Common fliM flagellar motor switch protein FliM GOX0696 101 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 58038857 Common - elongation factor Tu GOX0382 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 58040488 Common - hypothetical protein GOX2060 10 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 58040676 Common - Pyruvate kinase GOX2250 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 58040739 Common - ATP-dependent RNA helicase GOX2314 243 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 58040598 Nonpathogen - Transmembrane protein GOX2170 1 None None None 58039492 Common - hypothetical protein GOX1029 96 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 58040411 Common - Lipid A biosynthesis lauroyl acyltransferase GOX1983 105 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 58038847 Common - LSU ribosomal protein L29P GOX0372 13 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 58039895 Common - hypothetical protein GOX1454 32 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 58038646 Common - D-alanine--D-alanine ligase GOX0161 212 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 58040334 Common - Putative ATP-dependent helicase GOX1904 122 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 58039086 Common - hypothetical protein GOX0616 12 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 58039883 Common - Uncharacterized PQQ-dependent dehydrogenase 3 GOX1441 58 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 58040218 Common - Outer membrane protein GOX1787 118 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 58038639 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase GOX0154 204 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 58040240 Common - Signal peptidase I GOX1809 208 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 58039796 Common - Ribulose-phosphate 3-epimerase GOX1352 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 58039664 Common - Phage DNA Packaging Protein GOX1211 32 COG5323 COG5323, Uncharacterized conserved protein Function unknown 58040641 Common - Putative carbohydrate kinase GOX2214 179 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 58040517 Common - Glycerol uptake facilitator protein GOX2089 134 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 58040618 Common - Transcriptional regulator GOX2190 88 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 58040274 Common - ABC transporter ATP-binding protein GOX1843 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 58040282 Common - Glutamate synthase [NADPH] large chain GOX1852 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 58040636 Common - truncated transposase (class I) GOX2209 34 None None None 58040536 Common - NADH-dependent iron-containing alcohol dehydrogenase GOX2108 168 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 58040234 Common - putative sulfite oxidase subunit YedZ GOX1803 79 COG2717 COG2717, Predicted membrane protein Function unknown 58040009 Common - Transposase (class II) GOX1576 12 None None None 58039105 Common - GTP-binding protein GOX0636 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 58040871 Nonpathogen - Putative phage-related protein GOX2448 7 None None None 58038509 Common - Thymidylate kinase GOX0018 219 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 58038576 Common tig trigger factor GOX0088 213 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 58039967 Common - Outer membrane protein GOX1533 97 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 58040513 Nonpathogen - hypothetical protein GOX2085 1 None None None 58038846 Common - SSU ribosomal protein S17P GOX0371 226 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 58039803 Common - Excinuclease ABC subunit A GOX1359 234 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 58038777 Common ksgA dimethyladenosine transferase GOX0302 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 58039348 Common - hypothetical protein GOX0884 111 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 58040247 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase GOX1816 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 58040185 Common - hypothetical protein GOX1754 12 COG3147 DedD, Uncharacterized protein conserved in bacteria Function unknown 58038779 Common rplI 50S ribosomal protein L9 GOX0304 212 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 58039621 Common - Putative oxidoreductase GOX1168 112 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 58039201 Nonpathogen rpmJ 50S ribosomal protein L36 GOX0732 1 None None None 58039901 Common - glutaredoxin 2 GOX1460 18 COG2999 GrxB, Glutaredoxin 2 Posttranslational modification, protein turnover, chaperones 58039388 Common - UDP-glucose 6-dehydrogenase GOX0924 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 58040496 Common - manganese transport regulator MntR GOX2068 94 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 58038551 Common - prephenate dehydratase GOX0062 210 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 58038693 Common - Biotin carboxyl carrier protein of acetyl-CoA carboxylase GOX0212 164 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 58040211 Common rpsD 30S ribosomal protein S4 GOX1780 244 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 58039545 Common - A/G-specific adenine DNA glycosylase GOX1084 204 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 58039648 Common - Alanine racemase, C-terminus GOX1195 195 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 58040469 Common - Acyl carrier protein GOX2041 211 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 58040740 Common - hypothetical protein GOX2315 23 COG3660 COG3660, Predicted nucleoside-diphosphate-sugar epimerase Cell envelope biogenesis, outer membrane 58040771 Common - Bacteriophage tail sheath protein GOX2347 21 COG4386 COG4386, Mu-like prophage tail sheath protein gpL General function prediction only 58038781 Common - SSU ribosomal protein S6P GOX0306 200 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 58039834 Common - Methyltransferase GOX1390 214 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 58039729 Common - Organophopsphate acid anhydrase GOX1276 65 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 58039710 Common - DNA topoisomerase IV subunit B GOX1257 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 58038770 Common - Exopolysaccharide production protein GOX0295 177 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 58040588 Common - hypothetical protein GOX2160 116 COG2855 COG2855, Predicted membrane protein Function unknown 58038944 Nonpathogen - hypothetical protein GOX0472 1 None None None 58039460 Common - Transposase (class II) GOX0996 42 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 58039424 Common - Sensory box/GGDEF family protein GOX0960 177 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 58039599 Common - Hypothetical metabolite transport protein GOX1140 130 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 58040841 Common - Putative oxidoreductase GOX2418 176 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 58039271 Common - hypothetical protein GOX0805 19 None None None 58039837 Common - Acyltransferase GOX1393 59 COG4261 COG4261, Predicted acyltransferase General function prediction only 58039849 Common - hypothetical protein GOX1406 75 COG2983 COG2983, Uncharacterized conserved protein Function unknown 58039134 Common - Outer membrane receptor for ferric iron uptake GOX0665 52 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 58040762 Nonpathogen - hypothetical protein GOX2338 1 None None None 58038884 Common - hypothetical protein GOX0409 18 None None None 58038669 Common - Putative protein disulfide isomerase GOX0187 14 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 58038840 Common rplF 50S ribosomal protein L6 GOX0365 226 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 58039773 Common - Small heat shock protein GOX1329 69 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 58038571 Common - Biotin operon repressor/biotin--[acetyl-CoA-carboxylase] synthetase GOX0082 142 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 58040359 Common - Transposase (class I) GOX1929 58 None None None 58039214 Common - hypothetical protein GOX0745 116 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 58039698 Common - Riboflavin kinase GOX1245 211 COG0196 RibF, FAD synthase Coenzyme metabolism 58039562 Common - Glutamine synthetase GOX1101 226 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 58039865 Common - O-antigene export system permease protein GOX1422 98 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 58040910 Nonpathogen - hypothetical protein GOX2488 10 COG3827 COG3827, Uncharacterized protein conserved in bacteria Function unknown 58039443 Common - riboflavin synthase subunit alpha GOX0979 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 58038890 Common - Putative transport protein GOX0415 88 COG0679 COG0679, Predicted permeases General function prediction only 58038605 Common - hypothetical protein GOX0119 24 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 58038954 Common - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase GOX0482 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 58040501 Common purU formyltetrahydrofolate deformylase GOX2073 221 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 58039768 Common - Transposase (class II) GOX1324 43 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 58040465 Common - hypothetical protein GOX2037 10 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 58039024 Common - Heavy-metal ion transporter HelA GOX0554 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 58040917 Common - Nitrate ABC transporter ATP-binding protein GOX2495 246 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 58038596 Common - Putative thiamin pyrophosphokinase GOX0109 19 COG1443 Idi, Isopentenyldiphosphate isomerase Lipid metabolism 58038864 Common rplA 50S ribosomal protein L1 GOX0389 244 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 58039902 Common - Dipeptidyl peptidase IV GOX1461 101 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 58040579 Common - hypothetical protein GOX2151 16 COG4286 COG4286, Uncharacterized conserved protein related to MYG1 family Function unknown 58038629 Common - hypothetical protein GOX0144 38 COG3750 COG3750, Uncharacterized protein conserved in bacteria Function unknown 58039879 Common - Purine nucleoside permease GOX1437 11 COG5042 NUP, Purine nucleoside permease Nucleotide transport and metabolism 58040376 Common - Two component response regulator GOX1946 49 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 58040220 Nonpathogen - hypothetical protein GOX1789 1 None None None 58038534 Common - Phosphomannomutase GOX0044 241 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 58040401 Nonpathogen - hypothetical protein GOX1973 1 None None None 58038915 Common - Ornithine decarboxylase GOX0440 218 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 58038961 Nonpathogen - hypothetical protein GOX0490 1 None None None 58038499 Common - Putative oxidoreductase GOX0008 197 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 58040648 Common - Ribose ABC transporter, permease protein GOX2221 96 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 58039454 Common hisG ATP phosphoribosyltransferase catalytic subunit GOX0990 206 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 58040420 Common - Osmotically inducible protein C GOX1992 75 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 58040883 Nonpathogen - hypothetical protein GOX2460 1 None None None 58039742 Common - Biopolymer transport ExbD protein GOX1289 32 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 58039861 Common - Carbohydrate-selective porin GOX1418 16 COG3659 OprB, Carbohydrate-selective porin Cell envelope biogenesis, outer membrane 58040790 Nonpathogen - hypothetical protein GOX2366 1 None None None 58039583 Common - Glycosyltransferase GOX1123 143 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 58040784 Nonpathogen - hypothetical protein GOX2360 1 None None None 58040820 Common - Small heat shock protein GOX2397 72 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 58039792 Common - Methyl-accepting chemotaxis protein GOX1348 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 58039043 Common - Metallo-beta-lactamase superfamily protein GOX0573 195 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 58039709 Common - Putative permease GOX1256 56 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 58038934 Common - hypothetical protein GOX0460 5 COG4907 COG4907, Predicted membrane protein Function unknown 58039126 Common - Oligopeptide ABC transporter permease protein OppB GOX0657 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 58040460 Common - hypothetical protein GOX2032 12 COG1633 COG1633, Uncharacterized conserved protein Function unknown 58040858 Nonpathogen - hypothetical protein GOX2435 1 None None None 58039375 Common - Putative oxidoreductase GOX0911 22 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 58038522 Common - Bacterial Peptide Chain Release Factor 1 (RF-1) GOX0032 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 58040654 Common thiG thiazole synthase GOX2227 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 58040367 Common - Exopolyphosphatase GOX1937 180 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 58040141 Common - Gluconokinase GOX1709 80 COG3265 GntK, Gluconate kinase Carbohydrate transport and metabolism 58039949 Common - Single-stranded-DNA-specific exonuclease RecJ GOX1515 198 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 58040436 Common - PhoH-like protein GOX2008 198 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 58039606 Common - Gamma-glutamyl phosphate reductase GOX1147 187 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 58039525 Common - Glucose inhibited division protein B GOX1064 201 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 161898753 Common - 3-deoxy-manno-octulosonate cytidylyltransferase GOX0063 137 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 58040117 Common - ExbD/TolR family protein GOX1685 143 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 58040313 Common - Porphobilinogen deaminase GOX1883 221 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 58039760 Common - ATP synthase delta chain GOX1310 163 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 58039240 Common - Ribosomal-protein-alanine acetyltransferase GOX0774 187 COG0456 RimI, Acetyltransferases General function prediction only 58040922 Common - Formamidopyrimidine-DNA glycosylase GOX2500 181 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 58039237 Common - Ferric uptake regulation protein GOX0771 190 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 58038529 Common - Putative hemagglutinin-related protein GOX0039 54 COG2706 COG2706, 3-carboxymuconate cyclase Carbohydrate transport and metabolism 58040698 Common uvrC excinuclease ABC subunit C GOX2273 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 58040551 Common - Dipeptide-binding protein of ABC transport system GOX2123 208 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 58040090 Common aat leucyl/phenylalanyl-tRNA--protein transferase GOX1657 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 58039394 Common - Psp operon transcriptional activator PspF GOX0930 171 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 58039553 Common - Transcriptional regulator MarR family GOX1092 76 COG1846 MarR, Transcriptional regulators Transcription 58039956 Common recA recombinase A GOX1522 225 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 58040451 Common - Adenylate cyclase GOX2023 24 None None None 58040569 Common - Putative permease GOX2141 29 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 58039073 Common - hypothetical protein GOX0603 173 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 58039468 Common - hypothetical protein GOX1004 11 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 58040838 Common - NusB family protein GOX2415 145 COG0781 NusB, Transcription termination factor Transcription 58040132 Common - histidinol-phosphate aminotransferase GOX1700 232 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 58040722 Common - Murein transglycosylase GOX2297 158 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 58039548 Common - Acetolactate synthase large subunit GOX1087 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 58039260 Common - L-serine deaminase /L-threonine deaminase GOX0794 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 58040586 Common - Transcriptional regulator GOX2158 53 COG1522 Lrp, Transcriptional regulators Transcription 58039859 Common - Porin B precursur GOX1416 17 COG3659 OprB, Carbohydrate-selective porin Cell envelope biogenesis, outer membrane 58039563 Nonpathogen - hypothetical protein GOX1102 1 None None None 58040071 Common - Transposase (class I) GOX1638 58 None None None 58039098 Common - hypothetical protein GOX0629 134 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 58038859 Common rpsL 30S ribosomal protein S12 GOX0384 246 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 58039643 Common - Glucose-1-phosphatase GOX1190 16 None None None 58040759 Nonpathogen - Phage DNA packing protein GOX2335 1 None None None 58040621 Nonpathogen - hypothetical protein GOX2193 1 None None None 58040208 Common - Putative Na+ driven multidrug efflux pump GOX1777 160 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 58039328 Common - Acyl carrier protein phosphodiesterase GOX0862 99 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 58040750 Nonpathogen - hypothetical protein GOX2326 1 None None None 58039926 Common - Transposase (class I) GOX1491 58 None None None 58039368 Common - hypothetical protein GOX0904 61 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 58040112 Common ruvC Holliday junction resolvase GOX1680 198 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 58040547 Common - Dipeptide ABC transport system ATP-binding protein DppF GOX2119 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 58040577 Common - Low-affinity inorganic phosphate transporter GOX2149 89 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 58038985 Nonpathogen - hypothetical protein GOX0515 5 COG4313 COG4313, Protein involved in meta-pathway of phenol degradation Energy production and conversion 58040558 Nonpathogen - hypothetical protein GOX2130 1 None None None 58040429 Common - chorismate mutase GOX2001 69 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 58039940 Common - Putative type II DNA modification enzyme GOX1505 49 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 58038712 Common - Myo-inositol-1(or 4)-monophosphatase GOX0237 205 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 58039574 Common - Vitamin B12-dependent ribonucleotide reductase GOX1114 48 None None None 58038543 Nonpathogen - hypothetical protein GOX0054 2 None None None 58039579 Common - Alpha,alpha-trehalose-phosphate synthase GOX1119 96 COG0380 OtsA, Trehalose-6-phosphate synthase Carbohydrate transport and metabolism 58040025 Common - hypothetical protein GOX1592 31 COG5458 COG5458, Uncharacterized conserved protein Function unknown 58039343 Common - aspartate-semialdehyde dehydrogenase GOX0878 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 58038909 Common - hypothetical protein GOX0434 10 None None None 58038630 Common - glucose-6-phosphate 1-dehydrogenase GOX0145 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 58039298 Common - ATP-dependent helicase GOX0832 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 58040032 Common - Two component sensor histidine kinase GOX1599 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 58039167 Common - hypothetical protein GOX0698 106 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 58040846 Nonpathogen - hypothetical protein GOX2423 2 None None None 58039555 Common - hypothetical protein GOX1094 15 COG1359 COG1359, Uncharacterized conserved protein Function unknown 58038643 Common murG N-acetylglucosaminyl transferase GOX0158 207 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 58038942 Common - Putative peroxidase GOX0470 110 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 58038749 Common - Putative cell division protein FtsX GOX0274 20 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 58038673 Common - 3-Isopropylmalate dehydrogenase GOX0191 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 58040008 Nonpathogen - hypothetical protein GOX1575 3 None None None 58038696 Common - hypothetical protein GOX0215 24 COG5631 COG5631, Predicted transcription regulator, contains HTH domain (MarR family) Transcription 58038991 Common - Gamma-glutamyltranspeptidase GOX0521 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 58040472 Common - hypothetical protein GOX2044 31 COG2930 COG2930, Uncharacterized conserved protein Function unknown 58038839 Common rplR 50S ribosomal protein L18 GOX0364 216 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 58038691 Common - Putative carboxylase GOX0210 115 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 58039358 Nonpathogen - hypothetical protein GOX0894 1 None None None 58040861 Nonpathogen - hypothetical protein GOX2438 1 None None None 58039658 Common - Folylpolyglutamate synthase / dihydrofolate synthase GOX1205 214 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 58038516 Common - Amino acid permease GOX0025 192 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 58038869 Common - Two component sensor histidine kinase GOX0394 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 58040384 Common - Putative thiol:disulfide interchange protein I GOX1956 102 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 58039345 Nonpathogen - hypothetical protein GOX0880 1 None None None 58039950 Common glpX fructose 1,6-bisphosphatase II GOX1516 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 58039739 Common - hypothetical protein GOX1286 8 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 58040498 Common - malate:quinone oxidoreductase GOX2070 58 COG0579 COG0579, Predicted dehydrogenase General function prediction only 58039412 Common - hypothetical protein GOX0948 30 None None None 58040549 Common - Dipeptide ABC transport system permease protein DppC GOX2121 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 58039160 Common - Acriflavin resistance protein A (mulitdrug efflux system) GOX0691 143 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 58039489 Common - Flagellar hook-associated protein 1 FlgK GOX1026 43 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 58040805 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B GOX2382 213 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 58038819 Common - Adenine DNA methyltransferase GOX0344 135 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 58039109 Common - hypothetical protein GOX0640 7 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 58038794 Common - Putative oxidoreductase GOX0319 166 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 58040690 Common - Inosine-5'-monophosphate dehydrogenase GOX2265 239 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 58040156 Common - hypothetical protein GOX1725 17 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 58040039 Common - Lipopolysaccharide N-acetylglucosaminyltransferase I GOX1606 101 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 58040338 Common - Uracil-DNA glycosylase GOX1908 58 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 58039715 Common - Carboxy-terminal processing protease GOX1262 174 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 58040834 Nonpathogen - hypothetical protein GOX2411 2 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 58040818 Common - hypothetical protein GOX2395 4 COG5481 COG5481, Uncharacterized conserved small protein containing a coiled-coil domain Function unknown 58038907 Nonpathogen - hypothetical protein GOX0432 1 None None None 58039433 Common - hypothetical protein GOX0969 56 COG3975 COG3975, Predicted protease with the C-terminal PDZ domain General function prediction only 58040191 Common - hypothetical protein GOX1760 24 COG3187 HslJ, Heat shock protein Posttranslational modification, protein turnover, chaperones 58039982 Common - Methyl-accepting chemotaxis protein GOX1549 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 58038705 Common - hypothetical protein GOX0230 30 COG2335 COG2335, Secreted and surface protein containing fasciclin-like repeats Cell envelope biogenesis, outer membrane 58039304 Common - hypothetical protein GOX0838 13 COG0398 COG0398, Uncharacterized conserved protein Function unknown 58038792 Common - Cation efflux system protein GOX0317 93 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 58040610 Common - Probable mannitol/sorbitol ABC transporter permease protein GOX2182 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 58039977 Common - hypothetical protein GOX1543 149 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 58040881 Common - Phage Terminase Small Subunit GOX2458 29 COG3728 XtmA, Phage terminase, small subunit DNA replication, recombination, and repair 58039617 Common - N-formimino-L-glutamate deiminase GOX1164 124 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 58038974 Nonpathogen - hypothetical protein GOX0504 2 None None None 58039429 Common - Probable phosphoglycerate mutase 2 GOX0965 133 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 58038610 Common rpsU 30S ribosomal protein S21 GOX0124 35 None None None 58040362 Common - Glutathione S-transferase GOX1932 63 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 58039484 Common - hypothetical protein GOX1021 42 COG4717 COG4717, Uncharacterized conserved protein Function unknown 58040811 Common - Putative acetyltransferase (Antibiotic resistance ) protein GOX2388 129 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 58040103 Common apaG ApaG GOX1670 89 COG2967 ApaG, Uncharacterized protein affecting Mg2+/Co2+ transport Inorganic ion transport and metabolism 58039671 Common - Phage tail sheath protein GOX1218 13 None None None 58039017 Nonpathogen - hypothetical protein GOX0547 4 COG5267 COG5267, Uncharacterized protein conserved in bacteria Function unknown 58040126 Common fliI flagellum-specific ATP synthase GOX1694 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 58040895 Common - Phage-related DNA binding protein GOX2472 35 COG3617 COG3617, Prophage antirepressor Transcription 58040732 Nonpathogen - hypothetical protein GOX2307 2 None None None 58040245 Common - Undecaprenyl pyrophosphate synthetase GOX1814 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 58039261 Nonpathogen - hypothetical protein GOX0795 7 COG1887 TagB, Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC Cell envelope biogenesis, outer membrane 58040704 Common - Enolase GOX2279 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 58039515 Common - dTDP-glucose 4,6-dehydratase GOX1053 232 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 58039677 Nonpathogen - Phage-related baseplate assembly protein GOX1224 2 COG4540 gpV, Phage P2 baseplate assembly protein gpV General function prediction only 58039991 Nonpathogen - hypothetical protein GOX1558 2 None None None 58039061 Common - Zinc protease GOX0591 196 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 58038966 Nonpathogen - hypothetical protein GOX0495 1 None None None 58040095 Nonpathogen - hypothetical protein GOX1662 2 None None None 58040011 Nonpathogen - hypothetical protein GOX1578 2 None None None 58040167 Nonpathogen - hypothetical protein GOX1736 1 COG4907 COG4907, Predicted membrane protein Function unknown 58039141 Common - hypothetical protein GOX0672 108 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 58040668 Nonpathogen - hypothetical protein GOX2242 1 None None None 58038854 Common rplD 50S ribosomal protein L4 GOX0379 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 58038723 Nonpathogen - hypothetical protein GOX0248 1 None None None 58038832 Common - 30S ribosomal protein S11 GOX0357 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 58039632 Common - Putative sugar uptake ABC transporter permease protein GOX1179 97 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 58038548 Common - Putative transcriptional regulator cold shock protein GOX0059 177 COG1278 CspC, Cold shock proteins Transcription 58040053 Common - Two component response regulator GOX1620 44 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 58040524 Common - Sorbitol dehydrogenase large subunit GOX2096 6 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 58040293 Common - hypothetical protein GOX1863 30 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 58039536 Common - TonB-dependent outer membrane receptor GOX1075 64 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 58039405 Common - hypothetical protein GOX0941 134 COG1739 COG1739, Uncharacterized conserved protein Function unknown 58040173 Common - hypothetical protein GOX1742 13 COG3410 COG3410, Uncharacterized conserved protein Function unknown 58040099 Common - hypothetical protein GOX1666 14 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 58039337 Common - Signal peptidase I GOX0871 190 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 58039938 Common - Probable ATP-dependent helicase Lhr GOX1503 121 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 58038759 Common - Putative sugar kinase/putative transcriptional regulator GOX0284 166 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 58038586 Common - Putative transcriptional regulator GOX0099 78 COG1959 COG1959, Predicted transcriptional regulator Transcription 58038502 Common - Di-/tripeptide transporter GOX0011 75 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 58040746 Nonpathogen - Putative regulatory protein GOX2322 1 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 58038877 Common - Cell division inhibitor MinE GOX0402 73 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 58039919 Common - Capsule polysaccharide export inner-membrane protein GOX1484 40 COG3524 KpsE, Capsule polysaccharide export protein Cell envelope biogenesis, outer membrane 58040608 Common - TonB-dependent receptor (disrupted by IS element) GOX2180 105 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 58038737 Common - Phenylalanyl-tRNA synthetase alpha chain GOX0262 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 58039216 Common - Serine O-acetyltransferase CysE GOX0747 205 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 58039787 Common - Transposase (class III) GOX1343 154 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 58039151 Common - Predicted Na+-dependent transporter GOX0682 101 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 58039998 Common - Transposase (IS12528) GOX1565 64 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 58040303 Common - DNA mismatch repair protein GOX1873 200 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 58040276 Common - hypothetical protein GOX1845 9 COG5375 COG5375, Uncharacterized protein conserved in bacteria Function unknown 58040266 Common - Methionyl-tRNA formyltransferase GOX1835 217 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 58038913 Common - Rare lipoprotein A GOX0438 134 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 58040230 Common - Protein translocase subunit YajC GOX1799 94 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 58040253 Common - UDP-N-acetylglucosamine acyltransferase GOX1822 147 COG1043 LpxA, Acyl- acyl carrier protein 58039197 Common - Putative multidrug resistance efflux pump GOX0728 104 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 58040823 Nonpathogen - hypothetical protein GOX2400 1 None None None 58040728 Common - Phosphoribosylformylglycinamidine synthase GOX2303 228 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 58040531 Common - Putative secretion protein GOX2103 129 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 58039003 Common - hypothetical protein GOX0533 8 None None None 58038717 Common - hypothetical protein GOX0242 10 None None None 58040661 Common - Orotidine 5'-phosphate decarboxylase GOX2235 168 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 58039027 Nonpathogen - hypothetical protein GOX0557 11 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 58040216 Common - Carbonic anhydrase GOX1785 150 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 58040687 Common - Putative transmembrane protein GOX2261 49 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 58039052 Common - ABC-type Fe3+-siderophore transport system, ATP-binding protein GOX0582 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 58039190 Common - Biotin synthesis protein BioH GOX0721 15 None None None 58039639 Nonpathogen - hypothetical protein GOX1186 1 None None None 58040657 Common - Phosphomethylpyrimidine kinase ThiD GOX2230 218 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 58039181 Common - Glycosyltransferase GOX0712 59 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 58039386 Common - hypothetical protein GOX0922 13 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 58039910 Common - Putative N-acetylglucosamine kinase GOX1475 54 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 58040001 Common - Cytochrome b561 GOX1568 91 COG3038 CybB, Cytochrome B561 Energy production and conversion 58039815 Common - tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase GOX1371 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 58040596 Common - ATP synthase epsilon chain GOX2168 22 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 58040705 Common - hypothetical protein GOX2280 17 None None None 58040915 Common - Peptide methionine sulfoxide reductase GOX2493 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 58038659 Common - Ribonuclease H GOX0177 174 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 58038899 Common fliF flagellar MS-ring protein GOX0424 125 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 58038921 Common - Molybdenum cofactor biosynthesis protein A GOX0446 200 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 58040446 Common - Aldehyde dehydrogenase GOX2018 209 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 58040284 Common - Oligoendopeptidase F GOX1854 88 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 58040075 Common - Carboxypeptidase-related protein GOX1642 37 COG2939 COG2939, Carboxypeptidase C (cathepsin A) Amino acid transport and metabolism 58040484 Common - Serine palmitoyltransferase GOX2056 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 58040908 Common - Phage related integrase GOX2485 35 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 58038825 Common - Acriflavin resistance protein F GOX0350 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 58038812 Common - hypothetical protein GOX0337 44 COG3816 COG3816, Uncharacterized protein conserved in bacteria Function unknown 58038768 Common - leucyl aminopeptidase GOX0293 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 58040389 Common - DNA polymerase III, epsilon chain GOX1961 195 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 58040467 Common - acyl-carrier-protein S-malonyltransferase GOX2039 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 58039409 Common - TonB-dependent outer membrane receptor GOX0945 22 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 58038667 Common - hypothetical protein GOX0185 28 COG2363 COG2363, Uncharacterized small membrane protein Function unknown 58040843 Nonpathogen - hypothetical protein GOX2420 1 None None None 58038652 Common - DNA repair protein RecN GOX0167 198 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 58039511 Common - Glycosyltransferase GOX1049 72 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 58038575 Common - ATP-dependent Clp protease proteolytic subunit GOX0087 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 58040769 Common - hypothetical protein GOX2345 3 None None None 58039994 Nonpathogen - hypothetical protein GOX1561 1 None None None 58040307 Common - Glutathione peroxidase GOX1877 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 58039507 Common - Metal ABC transport system ATP-binding protein GOX1045 231 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 58039547 Common - tRNA delta(2)-isopentenylpyrophosphate transferase GOX1086 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 58040873 Nonpathogen - hypothetical protein GOX2450 1 None None None 58039062 Common - hypothetical protein GOX0592 8 COG4641 COG4641, Uncharacterized protein conserved in bacteria Function unknown 58038866 Common - Putative outer membrane channel protein GOX0391 107 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 58039937 Common - Transposase (class IV) GOX1502 55 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 58038679 Common - Signal recognition particle protein GOX0197 246 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 58039847 Common - Transposase (class II) GOX1403 43 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 58039705 Common - DNA mismatch repair protein MutL GOX1252 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 58038568 Common - prolyl-tRNA synthetase GOX0079 249 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 58038948 Common - Putative oxidoreductase GOX0476 109 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 58040301 Common - hypothetical protein GOX1871 47 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 58038952 Nonpathogen - hypothetical protein GOX0480 2 None None None 58039904 Common - ATP-dependent Clp protease, ATP-binding subunit ClpB GOX1463 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 58040438 Common - 1-Acyl-sn-glycerol-3-phosphate acyltransferase GOX2010 94 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 58039863 Common - Putative peroxiredoxin GOX1420 205 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 58039960 Common - Flagellar hook-basal body protein FleE GOX1526 19 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 58039928 Common - hypothetical protein GOX1493 10 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 58040623 Common - Transposase (class III) GOX2195 155 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 58040318 Common - Probable DNA-methyltransferase (DNA-modification methylase) protein GOX1888 112 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 58038708 Common - Lysyl-tRNA synthetase GOX0233 200 COG2269 COG2269, Truncated, possibly inactive, lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 58038997 Common - Alkylphosphonate uptake protein PhnA GOX0527 105 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 58040027 Common - coproporphyrinogen III oxidase GOX1594 211 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 58040357 Common - Nucleoside diphosphate kinase GOX1927 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 58040463 Common - hypothetical protein GOX2035 11 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 58038695 Nonpathogen - hypothetical protein GOX0214 2 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 58040029 Common - hypothetical protein GOX1596 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 58039666 Nonpathogen - Phage minor structual protein GP20 GOX1213 1 None None None 58040652 Common - thiamine biosynthesis protein ThiC GOX2225 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 58039897 Nonpathogen - hypothetical protein GOX1456 9 COG4421 COG4421, Capsular polysaccharide biosynthesis protein Carbohydrate transport and metabolism 58039887 Common - phosphoserine aminotransferase GOX1446 67 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 58039445 Common - 6,7-Dimethyl-8-ribityllumazine synthase GOX0981 230 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 58040748 Nonpathogen - hypothetical protein GOX2324 1 None None None 58038648 Common - Cell division protein FtsA GOX0163 173 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 58040675 Common - Aspartyl-tRNA synthetase GOX2249 38 COG3807 COG3807, Uncharacterized protein conserved in bacteria Function unknown 58040519 Common - Bacterial ring hydroxylating dioxygenase alpha-subunit GOX2091 13 None None None 58039274 Common - Galactose-proton symporter GOX0808 133 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 58038844 Common - LSU ribosomal protein L24P GOX0369 188 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 58038897 Nonpathogen - hypothetical protein GOX0422 1 None None None 58040594 Common - hypothetical protein GOX2166 17 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 58039970 Common - Bifunctional folate synthesis protein GOX1536 202 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 58039882 Common - S-adenosylmethionine:tRNA ribosyltransferase-isomerase GOX1440 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 58039030 Common - Diguanylate cyclase GOX0560 191 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 58038765 Common - Putative oxidoreductase GOX0290 198 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 58040182 Common - HesB family protein GOX1751 165 COG0316 IscA, Uncharacterized conserved protein Function unknown 58039392 Common - phosphoadenosine phosphosulfate reductase GOX0928 151 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 58040789 Nonpathogen - hypothetical protein GOX2365 1 None None None 58039724 Common - Putative oxidoreductase GOX1271 20 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 58040183 Common - Deoxyguanosinetriphosphate triphosphohydrolase GOX1752 161 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 58038496 Common - hypothetical protein GOX0005 6 None None None 58039707 Common - Outer membrane protein GOX1254 47 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 58039947 Nonpathogen - hypothetical protein GOX1512 1 None None None 58040444 Common - Transcriptional regulator GOX2016 83 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 58040720 Nonpathogen - hypothetical protein GOX2295 1 None None None 58039103 Nonpathogen - hypothetical protein GOX0634 6 COG4421 COG4421, Capsular polysaccharide biosynthesis protein Carbohydrate transport and metabolism 58039798 Common - Lipopolysaccharide biosynthesis protein GOX1354 218 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 58040020 Common - Putative 2-nitropropane dioxygenase GOX1587 44 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 58040494 Common - glutaminase GOX2066 72 COG2066 GlsA, Glutaminase Amino acid transport and metabolism 58040022 Common - Putative hydroxylase GOX1589 32 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 58040336 Common - hypothetical protein GOX1906 55 COG0392 COG0392, Predicted integral membrane protein Function unknown 58040453 Common - Putative ABC transporter system ATP-binding protein GOX2025 90 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 58040158 Nonpathogen - hypothetical protein GOX1727 1 None None None 58039533 Common - hypothetical protein GOX1072 4 None None None 58039556 Common - Aminomethyltransferase (Glycine cleavage system T protein) GOX1095 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 58040345 Common - Ferredoxin GOX1915 153 COG1146 COG1146, Ferredoxin Energy production and conversion 58040538 Common - Putative aldehyde dehydrogenase GOX2110 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 58038772 Common - hypothetical protein GOX0297 3 None None None 58039623 Common - Putative lactate dehydrogenase GOX1170 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 58039840 Common - 3-oxoacyl-(acyl carrier protein) synthase I GOX1396 212 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 58040533 Common - Transcriptional regulator GOX2105 90 COG0583 LysR, Transcriptional regulator Transcription 58040572 Common - Aminopeptidase N GOX2144 165 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 58040520 Common - Bacterial ring hydroxylating dioxygenase alpha-subunit GOX2092 75 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 58038541 Common - Aromatic-L-amino-acid decarboxylase GOX0052 115 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 58039079 Common - ATP-dependent Clp protease ATP-binding subunit ClpA GOX0609 222 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 58038514 Common - Putative toluene tolerance protein GOX0023 79 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 58040685 Common - Putative oxidoreductase GOX2259 36 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 58040073 Common - amidophosphoribosyltransferase GOX1640 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 58039217 Common - Aldose 1-epimerase GOX0748 94 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 58040110 Common secA preprotein translocase subunit SecA GOX1678 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 58040229 Common - ATP-dependent protease subunit GOX1798 89 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 58038815 Common - hypothetical protein GOX0340 31 None None None 58039466 Common - Bacterial Protein Translation Initiation Factor 1 (IF-1) GOX1002 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 58039757 Common nusG transcription antitermination protein NusG GOX1305 215 COG0250 NusG, Transcription antiterminator Transcription 58040395 Nonpathogen - hypothetical protein GOX1967 3 None None None 58040148 Common - hypothetical protein GOX1716 34 COG0433 COG0433, Predicted ATPase General function prediction only 58038620 Common - Protease IV GOX0134 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 58039039 Common - Aldehyde dehydrogenase-like protein GOX0569 112 COG1396 HipB, Predicted transcriptional regulators Transcription 58040134 Common - Putative outer membrane protein GOX1702 117 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 58040702 Common - LSU ribosomal protein L33P GOX2277 127 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 58038634 Common - hypothetical protein GOX0149 117 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 58039954 Common - ATP-dependent Clp protease proteolytic subunit GOX1520 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 58039592 Common - hypothetical protein GOX1133 31 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 58040418 Common - Enoyl-[acyl-carrier-protein] reductase [NADH] GOX1990 199 COG0623 FabI, Enoyl- acyl-carrier-protein 58039813 Common - Cysteine desulfurase II NifS GOX1369 235 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 58040570 Common - hypothetical protein GOX2142 14 None None None 58040799 Common - Transposase (class I) GOX2375 58 None None None 58039732 Common - hypothetical protein GOX1279 11 None None None 58039111 Common - Putative oxidoreductase GOX0642 86 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 58040562 Common - Peptidyl-dipeptidase DCP GOX2134 123 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 58039128 Nonpathogen - hypothetical protein GOX0659 2 None None None 58039693 Common - hypothetical protein GOX1240 12 None None None 58038710 Common - hypothetical protein GOX0235 35 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 58039572 Common - ATP synthase C chain GOX1112 20 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 58040903 Common - Transposase (class III) GOX2480 154 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 58040422 Common nrdF ribonucleotide-diphosphate reductase subunit beta GOX1994 159 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 58038905 Common - KDPG aldolase GOX0430 125 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 58040556 Common - Putative glycosyltransferase GOX2128 158 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 58039390 Common - Sulfate adenylyltransferase subunit 1 / adenylylsulfate kinase GOX0926 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 58040370 Common - Putative acid phosphatase GOX1940 10 COG2503 COG2503, Predicted secreted acid phosphatase General function prediction only 58038556 Common - Cystathionine beta-lyase GOX0067 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 58040507 Common - hypothetical protein GOX2079 8 COG3729 GsiB, General stress protein General function prediction only 58038660 Common - homoserine kinase GOX0178 66 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 58038871 Common - DNA recombination protein RmuC-like protein GOX0396 112 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 58039494 Nonpathogen - hypothetical protein GOX1031 1 None None None 58039744 Common flgH flagellar basal body L-ring protein GOX1291 98 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 58038614 Common - hypothetical protein GOX0128 24 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 58039794 Common - hypothetical protein GOX1350 11 COG2949 SanA, Uncharacterized membrane protein Function unknown 58039979 Common - ABC transporter ATP-binding protein GOX1545 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 58038747 Nonpathogen - hypothetical protein GOX0272 1 None None None 58040778 Common - Bacteriophage protein GOX2354 12 COG4381 COG4381, Mu-like prophage protein gp46 Function unknown 58038627 Common - gamma-glutamyl kinase GOX0142 191 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 58040715 Common - pyruvate dehydrogenase subunit beta GOX2290 218 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 58038520 Common - HemK family protein GOX0030 211 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 58039852 Common - ABC transporter ATP-binding protein GOX1409 231 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 58039718 Common - Hypothetical membrane-spanning protein GOX1265 169 COG0344 COG0344, Predicted membrane protein Function unknown 58038701 Common - 5-Formyltetrahydrofolate cyclo-ligase GOX0226 115 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 58040526 Common - Lactate permease GOX2098 104 COG1620 LldP, L-lactate permease Energy production and conversion 58040019 Common - polynucleotide phosphorylase/polyadenylase GOX1586 240 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 58040782 Nonpathogen - hypothetical protein GOX2358 1 None None None 58038637 Common - Transpeptidase FtsI GOX0152 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 58040760 Common - Bacteriophage terminase large subunit GOX2336 35 COG5525 COG5525, Bacteriophage tail assembly protein General function prediction only 58038936 Common - Transposase GOX0463 43 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 58039604 Common - Transcriptional regulator GOX1145 18 COG1846 MarR, Transcriptional regulators Transcription 58040300 Nonpathogen - hypothetical protein GOX1870 1 None None None 161898749 Common - Uncharacterized PQQ-dependent dehydrogenase 4 GOX0516 58 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 58039619 Common - urocanate hydratase GOX1166 97 COG2987 HutU, Urocanate hydratase Amino acid transport and metabolism 58038561 Common - arginyl-tRNA-protein transferase GOX0072 85 COG2935 COG2935, Putative arginyl-tRNA:protein arginylyltransferase Posttranslational modification, protein turnover, chaperones 58039136 Common - Copper resistance protein CopZ GOX0667 53 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 58040792 Common - SOS (error prone) mutagenesis protein UmuD GOX2368 20 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 58040315 Common - preprotein translocase subunit SecB GOX1885 104 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 161898750 Common rplM 50S ribosomal protein L13 GOX0452 220 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 58040201 Common - hypothetical protein GOX1770 49 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 58038536 Common - Outer-membrane lipoprotein carrier protein GOX0047 20 None None None 58039156 Common - hypothetical protein GOX0687 16 None None None 58039916 Common - Fatty acid hydroxylase GOX1481 10 COG3000 ERG3, Sterol desaturase Lipid metabolism 58039870 Common thyX FAD-dependent thymidylate synthase GOX1427 47 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 58039696 Common - Putative dioxygenase GOX1243 37 COG1791 COG1791, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 58040631 Common - Transposase (class I)/ siderophore receptor protein GOX2204 101 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 161898751 Common - carbamoyl phosphate synthase small subunit GOX0321 232 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 58040254 Common - hypothetical protein GOX1823 45 COG3494 COG3494, Uncharacterized protein conserved in bacteria Function unknown 58039315 Common - NADPH-dependent L-sorbose reductase GOX0849 90 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 58040696 Common - Exodeoxyribonuclease III GOX2271 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 58040193 Common - Putative RNA helicase GOX1762 98 COG4581 COG4581, Superfamily II RNA helicase DNA replication, recombination, and repair 58039330 Common - Dihydrodipicolinate reductase GOX0864 213 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 58039029 Common - putative hydroxylase GOX0559 44 COG3128 PiuC, Uncharacterized iron-regulated protein Function unknown 58040730 Common - hypothetical protein GOX2305 85 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 58038888 Common - Acetyl-coenzyme A synthetase GOX0413 216 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 58038999 Common - Putative oxidoreductase GOX0529 57 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 58039984 Common - Chemotaxis protein CheY GOX1551 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 58039482 Common - Putative exonuclease GOX1019 78 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 58039438 Common - Transcriptional regulator AadR (cyclic AMP receptor protein) GOX0974 134 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 58040458 Common - Chaperone protein DnaK GOX2030 206 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 58039513 Common - dTDP-4-dehydrorhamnose 3,5-epimerase GOX1051 165 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 58038703 Nonpathogen - hypothetical protein GOX0228 1 None None None 58040816 Common - Phosphoribosylaminoimidazole carboxylase ATPase subunit GOX2393 193 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 58040258 Common - putative inner membrane protein translocase component YidC GOX1827 213 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 58039431 Common - hypothetical protein GOX0967 17 None None None 58039775 Common - Oxidative stress regulatory protein OxyR GOX1331 192 COG0583 LysR, Transcriptional regulator Transcription 58040897 Nonpathogen - hypothetical protein GOX2474 1 None None None 58039192 Common - Dethiobiotin synthetase BioD GOX0723 149 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 58039178 Nonpathogen - hypothetical protein GOX0709 3 None None None 58038939 Common - Nitrogen assimilation regulatory protein NtrY GOX0467 214 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 58039594 Common - Prolipoprotein diacylglyceryl transferase GOX1135 204 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 58040129 Nonpathogen - hypothetical protein GOX1697 2 None None None 58039993 Common - hypothetical protein GOX1560 102 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 58039306 Nonpathogen - hypothetical protein GOX0840 1 None None None 58039263 Nonpathogen - hypothetical protein GOX0797 1 None None None 58040899 Nonpathogen - hypothetical protein GOX2476 1 None None None 58039301 Common - adenine phosphoribosyltransferase GOX0835 184 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 58039019 Nonpathogen - hypothetical protein GOX0549 2 None None None 58040243 Common - Uridylate kinase GOX1812 241 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 58038968 Common - hypothetical protein GOX0497 31 None None None 58040077 Common - hypothetical protein GOX1644 141 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 58040105 Nonpathogen - hypothetical protein GOX1673 2 None None None 58038930 Common - Mannose-6-phosphate isomerase GOX0455 165 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 58040108 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein GOX1676 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 58039291 Common - hypothetical protein GOX0825 67 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 58040776 Common - Bacteriophage tail protein GOX2352 17 COG4379 COG4379, Mu-like prophage tail protein gpP General function prediction only 58040682 Common - putative aminotransferase GOX2256 223 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 58039751 Common - Serine--pyruvate aminotransferase GOX1298 156 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 58039839 Common - hypothetical protein GOX1395 35 COG4258 COG4258, Predicted exporter General function prediction only 58040169 Common - Rod shape-determining protein MreC GOX1738 107 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 58039326 Common - CDG1D protein GOX0860 95 COG1959 COG1959, Predicted transcriptional regulator Transcription 58039750 Common - allantoate amidohydrolase GOX1297 85 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 58039944 Nonpathogen - hypothetical protein GOX1509 1 None None None 58038680 Nonpathogen - hypothetical protein GOX0198 2 COG3678 CpxP, P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein Intracellular trafficking and secretion / Cell motility and secretio / Signal transduction mechanisms / Inorganic ion transport and metabolism 58039630 Common - D-glutamate deacylase GOX1177 76 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 58038870 Common - DNA binding response regulator GOX0395 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 58039678 Nonpathogen - Putative phage tail protein GOX1225 2 COG3628 COG3628, Phage baseplate assembly protein W General function prediction only 58039011 Common - TonB-dependent outer membrane receptor GOX0541 68 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 58038645 Common - UDP-N-acetylenolpyruvoylglucosamine reductase GOX0160 164 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 58039200 Nonpathogen - hypothetical protein GOX0731 1 None None None 58039169 Common - Prolyl oligopeptidase family protein GOX0700 106 COG1505 COG1505, Serine proteases of the peptidase family S9A Amino acid transport and metabolism 58039734 Common - putative deoxyribonucleotide triphosphate pyrophosphatase GOX1281 236 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 58040848 Nonpathogen - hypothetical protein GOX2425 1 None None None 58040863 Common - hypothetical protein GOX2440 7 None None None 58038589 Common - Putative phosphoenolpyruvate carboxylase GOX0102 87 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 58038500 Common - Thiamin-phosphate pyrophosphorylase GOX0009 162 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 58039560 Common - hypothetical protein GOX1099 87 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 58039045 Common - Transcriptional regulator ArsR family GOX0575 109 COG0640 ArsR, Predicted transcriptional regulators Transcription 58039810 Common - ABC transporter ATP-binding protein GOX1366 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 58038591 Nonpathogen - hypothetical protein GOX0104 2 None None None 58040190 Common - seryl-tRNA synthetase GOX1759 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 58039347 Common kgd alpha-ketoglutarate decarboxylase GOX0882 147 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 58039487 Common - heat shock protein 90 GOX1024 151 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 58039096 Common - ATP-dependent nuclease subunit A GOX0627 203 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 58038790 Common - Sensory transduction histidine kinase GOX0315 48 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 58040382 Common - glutamyl-Q tRNA(Asp) synthetase GOX1954 247 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 58039308 Common - hypothetical protein GOX0842 2 None None None 58038558 Common - Hypothetical membrane-spanning protein GOX0069 105 COG0628 PerM, Predicted permease General function prediction only 58039107 Common - Aminoglycoside N3-acetyltransferase GOX0638 20 COG2746 COG2746, Aminoglycoside N3'-acetyltransferase Defense mechanisms 58039414 Common - Putative oxidoreductase GOX0950 220 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 58040321 Common - hypothetical protein GOX1891 6 None None None 58039509 Common - Sugar-proton symporter GOX1047 123 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 58040364 Common - phosphoribosylaminoimidazole synthetase GOX1934 226 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 58040663 Common - Protein translocase subunit SecB GOX2237 77 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 58038715 Common - hypothetical protein GOX0240 129 COG1360 MotB, Flagellar motor protein Cell motility and secretion 58040124 Common - MrsA GOX1692 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 58039673 Nonpathogen - hypothetical protein GOX1220 1 None None None 58039054 Nonpathogen - hypothetical protein GOX0584 1 None None None 58038928 Nonpathogen - hypothetical protein GOX0453 2 None None None 58040271 Common - hypothetical protein GOX1840 14 COG3654 Doc, Prophage maintenance system killer protein General function prediction only 58038731 Common - Peptidyl-prolyl cis-trans isomerase GOX0256 128 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 58040756 Nonpathogen - hypothetical protein GOX2332 1 None None None 58038814 Common - hypothetical protein GOX0339 59 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 58039497 Common - Putative oxidoreductase GOX1034 175 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 58039009 Common - hypothetical protein GOX0539 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 58039223 Common - Hypothetical protein in adhS 5' region GOX0755 44 COG1289 COG1289, Predicted membrane protein Function unknown 58039228 Common - Thioredoxin GOX0762 216 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 58039969 Common - Dihydropteroate synthase GOX1535 217 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 58040470 Common - 3-oxoacyl-(acyl carrier protein) synthase II GOX2042 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 58040475 Common - hypothetical protein GOX2047 16 None None None 58040067 Common - Pirin-like protein GOX1634 147 COG1741 COG1741, Pirin-related protein General function prediction only 58040003 Common - Heme exporter protein B GOX1570 81 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 58040607 Common - Transposase (IS12528) GOX2179 64 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 58039921 Common - Capsule polysaccharide export ATP-binding protein GOX1486 239 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 58039685 Common - Gluconate 2-dehydrogenase gamma chain GOX1232 17 None None None 58038788 Common - NAD-dependent alcohol dehydrogenase GOX0313 214 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 58040515 Common - Glycerol-3-phosphate regulon repressor GOX2087 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 58039070 Common - hypothetical protein GOX0600 11 None None None 58038763 Nonpathogen - hypothetical protein GOX0288 1 None None None 58039080 Nonpathogen - hypothetical protein GOX0610 2 None None None 58039569 Common - Dolichol-phosphate mannosyltransferase GOX1109 177 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 58039535 Common - hypothetical protein GOX1074 8 None None None 58038881 Nonpathogen - hypothetical protein GOX0406 1 None None None 58039000 Common - TonB protein GOX0530 32 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 58039353 Common - Peptidyl-prolyl cis-trans isomerase GOX0889 200 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 58040486 Common - acyl-CoA synthetase GOX2058 206 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 58039254 Nonpathogen - Flagellin assembly protein GOX0788 1 COG5442 FlaF, Flagellar biosynthesis regulator FlaF Cell motility and secretion 58040744 Nonpathogen - hypothetical protein GOX2320 1 None None None 58039828 Common - Transposase (class I) GOX1384 55 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 58040171 Common - Cell elongation specific D,D-transpeptidase GOX1740 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 58039602 Common - hypothetical protein GOX1143 2 None None None 58038744 Common - Sensory Transduction Protein Kinase GOX0269 208 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 58039472 Common - hypothetical protein GOX1009 11 None None None 58039589 Common - hypothetical protein GOX1130 10 COG5590 COG5590, Uncharacterized conserved protein Function unknown 58040051 Common - hypothetical protein GOX1618 43 None None None 58039234 Common - Transcriptional regulator GOX0768 39 COG1396 HipB, Predicted transcriptional regulators Transcription 58039322 Common - hypothetical protein GOX0856 10 None None None 58038584 Common - ABC transporter ATP-binding protein GOX0097 248 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 58040093 Nonpathogen - hypothetical protein GOX1660 1 None None None 58039379 Nonpathogen - hypothetical protein GOX0915 1 None None None 58039171 Common - Phosphate regulon response regulator PhoB GOX0702 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 58040278 Common - Ribonuclease D GOX1847 109 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 58038808 Common - hypothetical protein GOX0333 13 COG2861 COG2861, Uncharacterized protein conserved in bacteria Function unknown 58040901 Nonpathogen - hypothetical protein GOX2478 1 None None None 58038698 Common - N-methylhydantoinase B GOX0217 93 COG0146 HyuB, N-methylhydantoinase B/acetone carboxylase, alpha subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 58040291 Common - glutathione synthetase GOX1861 136 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 58040634 Common - Methylenetetrahydrofolate reductase GOX2207 143 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 58038998 Common - Putative iron-dependent peroxidase GOX0528 49 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 58040046 Common - Sensory box/GGDEF family protein GOX1613 165 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 58040268 Common - Small heat shock protein HspA GOX1837 64 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 58039456 Common - General secretion protein G GOX0992 68 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 58040088 Common - hypothetical protein GOX1655 23 None None None 58039805 Common - Two component response regulator GOX1361 214 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 58040416 Common - pyridoxamine 5'-phosphate oxidase GOX1988 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 58040851 Nonpathogen - hypothetical protein GOX2428 1 None None None 58038619 Common - Integration host factor beta-subunit GOX0133 202 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 58040202 Common - hypothetical protein GOX1771 3 None None None 58040821 Common rpmE 50S ribosomal protein L31 GOX2398 165 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 58040355 Common - hypothetical protein GOX1925 21 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 58040264 Nonpathogen - hypothetical protein GOX1833 2 None None None 58039227 Common - Putative oxidoreductase GOX0759 31 COG4529 COG4529, Uncharacterized protein conserved in bacteria Function unknown 58039450 Common - pyrroloquinoline quinone biosynthesis protein PqqB GOX0986 35 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 58038612 Common - flagellar motor protein MotA GOX0126 112 COG1291 MotA, Flagellar motor component Cell motility and secretion 58040650 Common - Transposase (class V) GOX2223 39 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 58040094 Common - Bacterioferritin comigratory protein GOX1661 214 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 58039400 Common - ABC transporter ATP-binding protein GOX0936 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 58040405 Common - Glutamate--cysteine ligase GOX1977 54 COG3572 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 58038791 Nonpathogen - hypothetical protein GOX0316 2 None None None 58039789 Common - Nicotinamide mononucleotide transporter GOX1345 52 COG3201 PnuC, Nicotinamide mononucleotide transporter Coenzyme metabolism 58038497 Common - GlmU GOX0006 235 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 58038895 Common flhA flagellar biosynthesis protein A GOX0420 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 58040224 Common - Transcriptional regulator GOX1793 89 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 58040581 Nonpathogen - hypothetical protein GOX2153 1 None None None 58039041 Common - hypothetical protein GOX0571 77 COG0730 COG0730, Predicted permeases General function prediction only 58040804 Common - hypothetical protein GOX2380 17 COG3613 COG3613, Nucleoside 2-deoxyribosyltransferase Nucleotide transport and metabolism 58040296 Common - PmbA protein GOX1866 161 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 58040257 Common - Ribonuclease P protein component GOX1826 24 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 58040139 Common - 6-Phosphogluconolactonase GOX1707 143 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 58039189 Common - 8-Amino-7-oxononanoate synthase GOX0720 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 58040363 Common - Phosphoribosylglycinamide formyltransferase protein GOX1933 221 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 58040041 Nonpathogen - hypothetical protein GOX1608 5 None None None 58038940 Common - Nitrogen assimilation regulatory protein NtrC GOX0468 145 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 58039566 Common - hypothetical protein GOX1105 52 None None None 58039255 Common - Peptidase GOX0789 20 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 58039784 Common - hypothetical protein GOX1340 37 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 58038750 Common - hypothetical protein GOX0275 29 COG1434 COG1434, Uncharacterized conserved protein Function unknown 58038980 Common - Exodeoxyribonuclease VII large subunit GOX0510 35 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 58040853 Common - hypothetical protein GOX2430 3 None None None 58039854 Common - Putative HlyD-family protein GOX1411 132 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 58039407 Common - hypothetical protein GOX0943 33 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 58038760 Common - hypothetical protein GOX0285 192 COG3260 COG3260, Ni,Fe-hydrogenase III small subunit Energy production and conversion 58040082 Common - Thiol:disulfide interchange protein DsbE precursor GOX1649 116 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 58039021 Common - Putative hydrolase GOX0551 204 COG0388 COG0388, Predicted amidohydrolase General function prediction only 58038754 Common - Cytochrome d ubiquinol oxidase subunit II GOX0279 154 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 58038802 Common - Uracil phosphoribosyltransferase GOX0327 165 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 58040628 Common - Transposase (class II) GOX2201 43 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 58040289 Common - excinuclease ABC subunit B GOX1859 229 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 58038787 Common - NAD(P) transhydrogenase subunit beta GOX0312 122 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 58039339 Common hemH ferrochelatase GOX0874 164 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 58039185 Common - short chain dehydrogenase GOX0716 231 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 58040736 Common - hypothetical protein GOX2311 15 COG2988 COG2988, Succinylglutamate desuccinylase Amino acid transport and metabolism 58040047 Common - Putative hexosyltransferase GOX1614 101 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 58038507 Common - Methionyl-tRNA synthetase GOX0016 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 58039646 Common - Alanine racemase GOX1193 176 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 58039499 Common - Putative phosphatase GOX1036 153 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 58039477 Common - Ferrichrome binding protein of ABC transporter GOX1014 21 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 58038738 Common rplT 50S ribosomal protein L20 GOX0263 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 58040064 Common - Putative sugar transport protein GOX1631 206 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 58039542 Common - Pyruvate decarboxylase GOX1081 217 COG3961 COG3961, Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only 58039703 Common - Putative lipoprotein signal peptidase GOX1250 145 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 58040780 Common - Bacteriophage tail protein GOX2356 18 COG3778 COG3778, Uncharacterized protein conserved in bacteria Function unknown 58038818 Common - hypothetical protein GOX0343 4 None None None 58040393 Common - dihydroorotase GOX1965 208 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 58040912 Common - hypothetical protein GOX2490 6 None None None 58040473 Common - Myo-inositol-1(or 4)-monophosphatase GOX2045 203 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 58040194 Common - Ferredoxin--NADP reductase GOX1763 108 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 58040058 Common - Chloride channel protein GOX1625 158 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 58040755 Common - Prophage replicative DNA helicase DnaB GOX2331 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 58040380 Common - hypothetical protein GOX1952 14 None None None 58040151 Common - Adenine deaminase GOX1719 75 COG1001 AdeC, Adenine deaminase Nucleotide transport and metabolism 58038604 Common - hypothetical protein GOX0118 26 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 58039891 Nonpathogen - hypothetical protein GOX1450 1 None None None 58039037 Common - Ubiquinol-cytochrome-c reductase GOX0567 41 COG2857 CYT1, Cytochrome c1 Energy production and conversion 58040905 Nonpathogen - hypothetical protein GOX2482 1 None None None 58039657 Common - Acetyl-coenzyme A carboxylase carboxyl transferase GOX1204 204 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 58039868 Common - hypothetical protein GOX1425 43 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 58039812 Common - Cysteine desulfurase I NifS GOX1368 217 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 58039800 Common - Oxidoreductase, iron-sulphur binding subunit GOX1356 147 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 58040079 Nonpathogen - hypothetical protein GOX1646 2 None None None 58039850 Nonpathogen - hypothetical protein GOX1407 1 None None None 58038925 Common - branched-chain amino acid aminotransferase GOX0450 204 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 58039355 Common - Single-strand DNA binding protein GOX0891 214 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 58039672 Nonpathogen - hypothetical protein GOX1219 2 None None None 58039264 Common - Serine protease, HtrA/DegQ/DegS family GOX0798 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 58038995 Common - Putative oxidoreductase GOX0525 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 58039824 Common - hypothetical protein GOX1380 28 COG5573 COG5573, Predicted nucleic-acid-binding protein, contains PIN domain General function prediction only 58038651 Common - Hypothetical lipoprotein GOX0166 128 COG4105 ComL, DNA uptake lipoprotein General function prediction only 58038745 Common - Sensory Transduction Protein Kinase GOX0270 221 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 58039207 Common - Non-heme chloroperoxidase GOX0738 120 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 58038963 Common - Putative regulatory protein GOX0492 74 COG2606 EbsC, Uncharacterized conserved protein Function unknown 58039302 Common - hypothetical protein GOX0836 154 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 58039091 Common flgI flagellar basal body P-ring protein GOX0621 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 58039913 Common - Capsule polysaccharide export protein GOX1478 30 COG3563 KpsC, Capsule polysaccharide export protein Cell envelope biogenesis, outer membrane 58039457 Common - BfpH protein (involved in biogenesis of type IV pili) GOX0993 24 None None None 58038803 Common - Transcriptional regulator GOX0328 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 58040695 Common - Two component response regulator GOX2270 213 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 58039417 Common flgG flagellar basal body rod protein FlgG GOX0953 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 58040456 Common - hypothetical protein GOX2028 4 None None None 58038525 Common - hypothetical protein GOX0035 72 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 58038856 Common rpsJ 30S ribosomal protein S10 GOX0381 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 58039246 Common - fructose-bisphosphate aldolase GOX0780 176 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 58040708 Common - hypothetical protein GOX2283 3 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 58039310 Common - DNA polymerase IV GOX0844 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 58039008 Common - Porin-like protein GOX0538 18 COG3659 OprB, Carbohydrate-selective porin Cell envelope biogenesis, outer membrane 58039162 Nonpathogen - hypothetical protein GOX0693 3 None None None 58038978 Common - Glyceraldehyde 3-phosphate dehydrogenase GOX0508 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 58040030 Common - rRNA methyltransferase RsmB GOX1597 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 58040248 Common - Putative membrane metalloprotease GOX1817 217 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 58040037 Nonpathogen - hypothetical protein GOX1604 1 None None None 58040888 Common - Putative phage-related protein GOX2465 18 None None None 58039505 Common - BfpH protein (involved in biogenesis of type IV pili) GOX1043 14 None None None 58039083 Common - Sugar phosphotransferase system protein GOX0613 46 COG3394 COG3394, Uncharacterized protein conserved in bacteria Function unknown 58039325 Common - Shikimate 5-dehydrogenase GOX0859 206 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 58039319 Common - Lipopolysaccharide biosynthesis protein GOX0853 213 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 58038694 Common - Biotin carboxylase GOX0213 224 COG0439 AccC, Biotin carboxylase Lipid metabolism 58038838 Common rpsE 30S ribosomal protein S5 GOX0363 247 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 58040700 Common - hypothetical protein GOX2275 4 None None None 58038798 Nonpathogen - hypothetical protein GOX0323 1 None None None 58040326 Common - coproporphyrinogen III oxidase GOX1896 113 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 58040478 Common - hypothetical protein GOX2050 10 COG3000 ERG3, Sterol desaturase Lipid metabolism 58039807 Nonpathogen - hypothetical protein GOX1363 1 None None None 58038684 Common metX homoserine O-acetyltransferase GOX0203 133 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 58040385 Common - Putative thiol:disulfide interchange protein II GOX1957 90 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 58039205 Common xerC site-specific tyrosine recombinase XerC GOX0736 228 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 58040866 Nonpathogen - hypothetical protein GOX2443 1 None None None 58039820 Common - Transposase (class III) GOX1376 154 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 58039012 Common - Hypothetical metabolite transport protein GOX0542 141 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 58038678 Common rpsP 30S ribosomal protein S16 GOX0196 212 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 58038728 Common - Hemolysin HlyA GOX0253 131 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 58040431 Common - Chromosome partition protein Smc GOX2003 175 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 58038971 Common - 23S rRNA methyltransferase GOX0501 212 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 58039144 Common - Alkaline phosphatase GOX0675 58 COG3540 PhoD, Phosphodiesterase/alkaline phosphatase D Inorganic ion transport and metabolism 58038828 Nonpathogen - hypothetical protein GOX0353 1 None None None 58039193 Common mdoG glucan biosynthesis protein G GOX0724 50 COG3131 MdoG, Periplasmic glucans biosynthesis protein Inorganic ion transport and metabolism 58039121 Common - Xanthine dehydrogenase Xdh C protein GOX0652 66 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 58039332 Common - S-adenosylmethionine synthetase GOX0866 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 58039399 Common - ABC transporter permease protein GOX0935 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 58040815 Common - DNA repair protein RadC GOX2392 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 58040777 Common - Bacteriophage protein GOX2353 17 COG4384 COG4384, Mu-like prophage protein gp45 Function unknown 58039651 Common - Sulfite reductase (Ferredoxin) GOX1198 169 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 58040602 Common - F0F1 ATP synthase subunit alpha GOX2174 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 58039830 Common - hypothetical protein GOX1386 97 COG3177 COG3177, Uncharacterized conserved protein Function unknown 58040212 Common - Bacterial Peptide Chain Release Factor 3 (RF-3) GOX1781 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 58039064 Nonpathogen - hypothetical protein GOX0594 1 None None None 58039028 Common - Transposase (class IV) GOX0558 55 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 58039321 Common - D-Sorbitol dehydrogenase subunit SldB GOX0855 10 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 58039942 Common - Putative restriction endonuclease GOX1507 33 COG3440 COG3440, Predicted restriction endonuclease Defense mechanisms 58040351 Common - Putative nucleotide sugar epimerase dehydratase protein GOX1921 144 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 58039481 Common - hypothetical protein GOX1018 3 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 58038885 Common leuS leucyl-tRNA synthetase GOX0410 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 58040320 Common - hypothetical protein GOX1890 7 COG4421 COG4421, Capsular polysaccharide biosynthesis protein Carbohydrate transport and metabolism 58039370 Common - Transcriptional regulator LysR family GOX0906 181 COG0583 LysR, Transcriptional regulator Transcription 58039243 Common - NifU protein GOX0777 121 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 58039779 Common - aconitate hydratase GOX1335 222 COG1048 AcnA, Aconitase A Energy production and conversion 58039972 Common - short chain dehydrogenase GOX1538 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 58039095 Common - Thioredoxin GOX0626 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 58039519 Common - Transposase (class I) GOX1057 58 None None None 58039997 Common - hypothetical protein GOX1564 16 None None None 58039753 Common - D-3-phosphoglycerate dehydrogenase GOX1300 226 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 58039265 Common - Cytosine deaminase GOX0799 212 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 58038706 Nonpathogen - hypothetical protein GOX0231 2 None None None 58040162 Common - Ribonuclease E GOX1731 184 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 58040195 Common - Glutathione reductase GOX1764 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 58040459 Common - Biotin synthase GOX2031 178 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 58039772 Nonpathogen - hypothetical protein GOX1328 1 None None None 58039397 Nonpathogen - hypothetical protein GOX0933 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 58039046 Nonpathogen - hypothetical protein GOX0576 5 None None None 58038726 Common - Dimethylallyltransferase GOX0251 240 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 58038492 Common dnaA chromosomal replication initiation protein GOX0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 58040625 Common - Transposase (class I) GOX2198 57 None None None 58040528 Nonpathogen - hypothetical protein GOX2100 1 None None None 58039155 Common - Transposase (class I) GOX0686 57 None None None 58039587 Common - DNA-binding protein HU-beta GOX1127 139 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 58039608 Common - hypothetical protein GOX1149 201 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 58040796 Common - Transcriptional regulator GOX2372 105 COG0583 LysR, Transcriptional regulator Transcription 58039876 Common - hypothetical protein GOX1434 11 None None None 58039148 Common - Conserved protein of the SAM superfamily GOX0679 100 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 58040160 Common - Exodeoxyribonuclease VII large subunit GOX1729 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 58040567 Common - hypothetical protein GOX2139 113 COG2353 COG2353, Uncharacterized conserved protein Function unknown 58039123 Common - Xanthine dehydrogenase XdhA protein GOX0654 121 COG4630 XdhA, Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A Nucleotide transport and metabolism 58040273 Common - RNA polymerase sigma-54 factor RpoN GOX1842 144 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 58040544 Common - Transcriptional regulator GOX2116 130 COG1802 GntR, Transcriptional regulators Transcription 58040317 Common - Membrane-bound lytic murein transglycosylase GOX1887 93 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 58039158 Common - Probable outer membrane efflux lipoprotein GOX0689 110 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 58040323 Common - hypothetical protein GOX1893 21 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 58039377 Common - Putative transport protein GOX0913 10 COG4982 COG4982, 3-oxoacyl- acyl-carrier protein 58038538 Common - DnaJ family protein GOX0049 80 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 58040414 Nonpathogen - hypothetical protein GOX1986 1 None None None 58039872 Common - Probable serine protease GOX1430 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 58039603 Nonpathogen - hypothetical protein GOX1144 2 None None None 58040794 Common - Na+/H+ antiporter NhaA GOX2370 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 58040644 Common tpiA triosephosphate isomerase GOX2217 216 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 58038617 Common - Thioredoxin reductase GOX0131 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 58040653 Common - Thiamine biosynthesis oxidoreductase ThiO GOX2226 90 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 58038531 Common - Glutaredoxin GOX0041 51 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 58039293 Common - hypothetical protein GOX0827 15 COG2968 COG2968, Uncharacterized conserved protein Function unknown 58039475 Common - Ferrichrome ABC transporter ATP-binding protein GOX1012 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 58038564 Common rpsB 30S ribosomal protein S2 GOX0075 217 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 58040890 Nonpathogen - hypothetical protein GOX2467 1 None None None 58038632 Common - Putative lipase GOX0147 122 COG0657 Aes, Esterase/lipase Lipid metabolism 58038902 Nonpathogen - hypothetical protein GOX0427 1 None None None 58039694 Common - Sec-independent protein translocase protein TatA GOX1241 5 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 58040605 Common - hypothetical protein GOX2177 30 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 58039790 Common - hypothetical protein GOX1346 16 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 58038546 Common - Sensory box/GGDEF family protein GOX0057 166 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 58039288 Nonpathogen - hypothetical protein GOX0822 1 None None None 58039914 Common - Capsule export protein GOX1479 30 COG3562 KpsS, Capsule polysaccharide export protein Cell envelope biogenesis, outer membrane 58039597 Common - Catalase GOX1138 124 COG0753 KatE, Catalase Inorganic ion transport and metabolism 58040018 Common - SSU ribosomal protein S15P GOX1585 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 58039567 Common - O-antigen biosynthesis protein RfbC GOX1107 182 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 58038821 Common - hypothetical protein GOX0346 2 None None None 58039503 Common - hypothetical protein GOX1041 9 None None None 58040709 Common - Triosephosphate isomerase GOX2284 217 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 58038527 Common - Aspartate kinase GOX0037 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 58039085 Common - Ceramide glucosyltransferase GOX0615 28 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 58038764 Nonpathogen - hypothetical protein GOX0289 1 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 58040120 Common - Peptidoglycan-associated lipoprotein GOX1688 151 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 58040454 Common - hypothetical protein GOX2026 6 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 58039532 Common - Putative oxidoreductase GOX1071 83 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 58040115 Common - hypothetical protein GOX1683 122 COG0824 FcbC, Predicted thioesterase General function prediction only 58038714 Common - MotA/TolQ/ExbB proton channel family protein GOX0239 28 None None None 58038625 Common rpmA 50S ribosomal protein L27 GOX0140 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 58040145 Common - Protease I GOX1713 164 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 58039691 Common - D-aminopeptidase GOX1238 94 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 58039756 Common - hypothetical protein GOX1304 7 COG3009 COG3009, Uncharacterized protein conserved in bacteria Function unknown 58040204 Common - Putative LacX protein GOX1773 42 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 58039364 Common - hypothetical protein GOX0900 14 COG3528 COG3528, Uncharacterized protein conserved in bacteria Function unknown 58039933 Common - hypothetical protein GOX1498 40 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 58040392 Common - Asparagine synthetase [glutamine-hydrolyzing] GOX1964 149 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 58038513 Common - hypothetical protein GOX0022 8 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 58040504 Common - Putative transcriptional regulator GOX2076 48 COG1309 AcrR, Transcriptional regulator Transcription 58040399 Common - Galactose-proton symporter GOX1971 93 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 58040575 Common - Endonuclease GOX2147 45 COG1864 NUC1, DNA/RNA endonuclease G, NUC1 Nucleotide transport and metabolism 58039769 Common - Transposase (class III) GOX1325 146 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 58039570 Common - ATP synthase B' chain GOX1110 13 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 58040433 Common - Putative thiol:disulfide interchange protein GOX2005 55 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 58038689 Common - Putative glucarate/galactarate transporter GOX0208 193 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 58039644 Common - Bacterioferritin GOX1191 111 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 58040140 Common - Ribose 5-phosphate isomerase GOX1708 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 58040188 Common - Sec-independent protein translocase protein TatB GOX1757 46 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 58039624 Common - histidinol-phosphate aminotransferase GOX1171 239 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 58038773 Common - hypothetical protein GOX0298 108 COG0795 COG0795, Predicted permeases General function prediction only 58039550 Common - ketol-acid reductoisomerase GOX1089 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 58039660 Nonpathogen - Probable transcriptional regulator GOX1207 1 COG1396 HipB, Predicted transcriptional regulators Transcription 58038607 Common - Transcriptional regulator GOX0121 217 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 58039540 Nonpathogen - hypothetical protein GOX1079 1 None None None 58040441 Common - Putative flagellin modification protein FlbA GOX2013 48 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 58040341 Common - Cytochrome o ubiquinol oxidase subunit II GOX1911 137 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 58040330 Common - Putative carboxymethylenebutenolidase GOX1900 102 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 58040378 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein GOX1950 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 58040787 Nonpathogen - hypothetical protein GOX2363 2 None None None 58040312 Common - O-sialoglycoprotein endopeptidase GOX1882 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 58040424 Common - Decaprenyl diphosphate synthase GOX1996 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 58039762 Common - F0F1 ATP synthase subunit gamma GOX1312 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 58040298 Common - threonine synthase GOX1868 149 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 58040671 Common - hypothetical protein GOX2245 6 None None None 58039559 Common - hypothetical protein GOX1098 2 COG1359 COG1359, Uncharacterized conserved protein Function unknown 58039669 Nonpathogen - hypothetical protein GOX1216 1 None None None 58040632 Common - hypothetical protein GOX2205 24 None None None 58039719 Common - Dihydroorotase GOX1266 207 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 58038572 Common - DNA-binding protein HU GOX0084 204 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 58040532 Common - Putative transport protein GOX2104 160 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 58039962 Common - Flagellar basal-body rod protein FlgB GOX1528 43 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 58040353 Nonpathogen - hypothetical protein GOX1923 2 None None None 58040727 Common - hypothetical protein GOX2302 3 None None None 58040491 Common - hypothetical protein GOX2063 39 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 58039490 Common flgE flagellar hook protein FlgE GOX1027 136 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 58039634 Common - Sugar uptake ABC transporter permease protein GOX1181 175 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 58038843 Common rplE 50S ribosomal protein L5 GOX0368 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 58039885 Common - MazG nucleotide pyrophosphohydrolase GOX1443 156 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 58039101 Common - D-amino acid dehydrogenase small subunit GOX0632 143 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 58039360 Common - hypothetical protein GOX0896 5 None None None 58040005 Common - Amino acid ABC transporter ATP-binding protein GOX1572 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 58038785 Common - NAD(P) transhydrogenase subunit alpha GOX0310 166 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 58040766 Nonpathogen - hypothetical protein GOX2342 7 None None None 58040678 Common - hypothetical protein GOX2252 12 COG0392 COG0392, Predicted integral membrane protein Function unknown 58039770 Nonpathogen - hypothetical protein GOX1326 2 None None None 58039137 Nonpathogen - hypothetical protein GOX0668 1 None None None 58039745 Common - Putative oxidoreductase GOX1292 159 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 58039211 Common - hypothetical protein GOX0742 9 None None None 58040024 Nonpathogen - hypothetical protein GOX1591 1 None None None 58039907 Common - Transposase GOX1472 62 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 58040680 Common - Putative glycosyl transferase GOX2254 56 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 58040170 Common - hypothetical protein GOX1739 8 None None None 58040306 Nonpathogen - hypothetical protein GOX1876 30 None None None 58039923 Common - UDP-galactopyranose mutase GOX1488 60 COG0562 Glf, UDP-galactopyranose mutase Cell envelope biogenesis, outer membrane 58039777 Common - Alkyl hydroperoxide reductase subunit F GOX1333 248 COG3634 AhpF, Alkyl hydroperoxide reductase, large subunit Posttranslational modification, protein turnover, chaperones 58040828 Common - two-component response regulator GOX2405 101 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 58039422 Common - Putative esterase/lipase GOX0958 154 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 58039446 Nonpathogen - hypothetical protein GOX0982 4 None None None 58038860 Common - DNA-directed RNA polymerase subunit beta' GOX0385 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 58039464 Nonpathogen - hypothetical protein GOX1000 1 None None None 58039582 Common - Putative NAD-dependent aldehyde dehydrogenase GOX1122 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 58039130 Common - hypothetical protein GOX0661 50 COG3545 COG3545, Predicted esterase of the alpha/beta hydrolase fold General function prediction only 58038893 Common ppnK inorganic polyphosphate/ATP-NAD kinase GOX0418 233 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 58039844 Common - Putative oxidoreductase GOX1400 99 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 58039208 Common - Transcriptional regulator, Mer family GOX0739 126 COG0789 SoxR, Predicted transcriptional regulators Transcription 58039728 Common - ATP-binding protein of ABC transporter GOX1275 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 58039221 Common - Putative acetyltransferase GOX0752 5 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 58039067 Common - Cytidylate kinase GOX0597 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 58039034 Common - Cytochrome c precursor GOX0564 31 None None None 58040238 Common - GTP pyrophosphokinase GOX1807 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 58038947 Nonpathogen - hypothetical protein GOX0475 2 None None None 58040461 Common - hypothetical protein GOX2033 10 None None None 58038950 Common - Putative oxidoreductase GOX0478 92 COG0778 NfnB, Nitroreductase Energy production and conversion 58038842 Common rpsN 30S ribosomal protein S14 GOX0367 206 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 58038664 Nonpathogen - hypothetical protein GOX0182 2 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 58039075 Common - Gamma-glutamyltranspeptidase GOX0605 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 58040471 Common - hypothetical protein GOX2043 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 58040232 Common - Putative oxidoreductase GOX1801 169 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 58038783 Common - RNA polymerase sigma factor RpoD GOX0308 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 58040043 Common - Putative D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase GOX1610 124 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 58039826 Common - Transposase (class I) GOX1382 58 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 58039809 Nonpathogen - ABC transporter permease protein GOX1365 1 None None None 58039822 Nonpathogen - hypothetical protein GOX1378 1 None None None 58040069 Common - 5-aminolevulinate synthase GOX1636 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 58040775 Common - Bacteriophage protein GOX2351 21 COG4228 COG4228, Mu-like prophage DNA circulation protein General function prediction only 58039357 Common - Transposase (class I) GOX0893 57 None None None 58039766 Common - Transposase (class I) GOX1322 35 None None None 58039517 Common - hypothetical protein GOX1055 118 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 58040773 Nonpathogen - hypothetical protein GOX2349 1 None None None 58038592 Common - Protein Translation Elongation Factor G (EF-G) GOX0105 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 58040659 Nonpathogen - hypothetical protein GOX2232 3 None None None 58039350 Common - hypothetical protein GOX0886 18 None None None 58040664 Common - Putative glycosyl transferase GOX2238 21 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 58038733 Common - Putative cytochrome c-552 GOX0258 11 None None None 58040177 Common - Rubredoxin-NAD(+) reductase GOX1746 223 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 58040130 Common - Aminopeptidase GOX1698 56 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 58040686 Common - Squalene-hopene cyclase GOX2260 45 COG1657 SqhC, Squalene cyclase Lipid metabolism 58039419 Common - hypothetical protein GOX0955 81 COG3146 COG3146, Uncharacterized protein conserved in bacteria Function unknown 58039183 Common - HlyD family secretion protein GOX0714 115 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 58039893 Common - Putative oxidoreductase GOX1452 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 58039022 Nonpathogen - hypothetical protein GOX0552 1 None None None 58038719 Common - Hypothetical membrane-spanning protein GOX0244 34 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 58039735 Common - Ribonuclease PH GOX1282 183 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 58040294 Common - protoheme IX farnesyltransferase GOX1864 166 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 58039411 Common - Inosine-uridine preferring nucleoside hydrolase GOX0947 88 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 58039802 Common - hypothetical protein GOX1358 15 COG1556 COG1556, Uncharacterized conserved protein Function unknown 58040056 Common - hypothetical protein GOX1623 30 COG3526 COG3526, Uncharacterized protein conserved in bacteria Posttranslational modification, protein turnover, chaperones 58038581 Common - Phenylacetic acid degradation protein PaaD GOX0094 146 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 58040914 Common - Alpha-amino acid ester hydrolase GOX2492 52 COG2936 COG2936, Predicted acyl esterases General function prediction only 58040643 Nonpathogen - hypothetical protein GOX2216 2 COG1830 FbaB, DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes Carbohydrate transport and metabolism 58040826 Common - Putative oxidoreductase GOX2403 177 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 58038505 Common - PhnP protein GOX0014 78 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 58039382 Common - hypothetical protein GOX0918 19 None None None 58039251 Common - DNA polymerase related protein GOX0785 154 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 58039187 Common - hypothetical protein GOX0718 110 COG0397 COG0397, Uncharacterized conserved protein Function unknown 58039258 Common - Methylene-THF dehydrogenase GOX0792 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 58038743 Common - SufE protein probably involved in Fe-S center assembly GOX0268 98 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 58039628 Common - Translation initiation inhibitor GOX1175 15 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 58040374 Common - Diaminopimelate decarboxylase GOX1944 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 58040802 Common - Short chain alcohol dehydrogenase GOX2378 208 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 58040287 Common - Uncharacterized PQQ-containing dehydrogenase 1 GOX1857 60 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 58038611 Common - Prolyl-oligopeptidase GOX0125 99 COG1505 COG1505, Serine proteases of the peptidase family S9A Amino acid transport and metabolism 58039470 Nonpathogen - hypothetical protein GOX1007 9 COG5400 COG5400, Uncharacterized protein conserved in bacteria Function unknown 58039051 Common - Iron-chelating periplasmic-binding protein GOX0581 91 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 58040809 Common - hypothetical protein GOX2386 44 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 58039153 Common - hypothetical protein GOX0684 47 COG1289 COG1289, Predicted membrane protein Function unknown 58040207 Common cysS cysteinyl-tRNA synthetase GOX1776 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 58039093 Common - hypothetical protein GOX0624 33 COG5352 COG5352, Uncharacterized protein conserved in bacteria Function unknown 58040080 Common - Cytochrome c-type biogenesis protein CycH GOX1647 28 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 58039683 Common - Gluconate 2-dehydrogenase, cytochrome c subunit GOX1230 75 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 58039225 Common - Inorganic pyrophosphatase GOX0757 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 58039402 Common - hypothetical protein GOX0938 17 None None None 58039230 Common - hypothetical protein GOX0764 97 COG2835 COG2835, Uncharacterized conserved protein Function unknown 58039856 Common - Putative hydrolase GOX1413 31 COG2267 PldB, Lysophospholipase Lipid metabolism 58040448 Common - Ribonuclease I GOX2020 13 COG3719 Rna, Ribonuclease I Translation, ribosomal structure and biogenesis 58040428 Common - Phosphohistidine phosphatase GOX2000 85 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 58039636 Common - hypothetical protein GOX1183 60 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 58040583 Common - ABC transporter permease protein GOX2155 23 COG3694 COG3694, ABC-type uncharacterized transport system, permease component General function prediction only 58038824 Common - Acriflavin resistance protein D GOX0349 178 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 58039176 Common - DNA starvation/stationary phase protection protein Dps GOX0707 142 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 58040523 Common - Sorbitol dehydrogenase large subunit GOX2095 68 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 58038756 Common - Putative methyltransferase GOX0281 30 None None None 161898748 Common clpS ATP-dependent Clp protease adaptor protein ClpS GOX0608 119 COG2127 COG2127, Uncharacterized conserved protein Function unknown 58039195 Nonpathogen - hypothetical protein GOX0726 2 None None None 58040920 Common - bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase GOX2498 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 58038752 Nonpathogen - hypothetical protein GOX0277 1 None None None 58039014 Common - Transcriptional regulator TetR family GOX0544 38 COG1309 AcrR, Transcriptional regulator Transcription 58040718 Common - lipoyl synthase GOX2293 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 58040408 Common - Putative corrin/porphyrin methyltransferase GOX1980 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 58039142 Common - Ferrous iron transport protein A (FeoA) GOX0673 16 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 58039048 Common - Transposase (IS12528) GOX0578 51 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 58040540 Common - Outer membrane protein GOX2112 113 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 58039372 Common - hypothetical protein GOX0908 12 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 58039239 Common - Transposase (class IV) GOX0773 55 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 58039341 Common anmK anhydro-N-acetylmuramic acid kinase GOX0876 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 58039334 Common - Electron transfer flavoprotein-ubiquinone oxidoreductase/ putative oxidoreductase GOX0868 109 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 58039479 Nonpathogen - hypothetical protein GOX1016 3 None None None 58039989 Common - Chemotaxis protein CheY GOX1556 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 58039712 Nonpathogen - hypothetical protein GOX1259 2 None None None 58040830 Common - Putative RNA polymerase sigma-E factor (sigma-24) protein 2 GOX2407 161 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 58039282 Common - HPr kinase GOX0816 72 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 58040615 Common - Gluconate 5-dehydrogenase GOX2187 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 58040153 Common - Transposase (class III) GOX1721 154 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 58040197 Common - Non-heme chloroperoxidase GOX1766 149 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 58038720 Common - Putative membrane transport protein GOX0245 135 COG2252 COG2252, Permeases General function prediction only 58040813 Common - DNA helicase II GOX2390 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 58040711 Common - anthranilate synthase component I GOX2286 221 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 58040600 Common - ATP synthase subunit c GOX2172 31 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 58039146 Common - Iron transport regulator protein/ sensor kinase GOX0677 41 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 58038923 Common - hypothetical protein GOX0448 101 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 58040097 Common - recombination factor protein RarA GOX1664 211 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 58039006 Common - Hydroxamate-type ferrisiderophore receptor GOX0536 104 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 58038983 Common - Glutamate uptake regulatory protein GOX0513 143 COG1522 Lrp, Transcriptional regulators Transcription 58040101 Common - hypothetical protein GOX1668 7 COG3755 COG3755, Uncharacterized protein conserved in bacteria Function unknown 58040734 Common - Amino acid permease GOX2309 174 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 58040164 Common - 2-Isopropylmalate synthase GOX1733 213 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 58038883 Nonpathogen - hypothetical protein GOX0408 3 COG3629 DnrI, DNA-binding transcriptional activator of the SARP family Signal transduction mechanisms 58039774 Common - Transposase (class I) GOX1330 58 None None None 58039436 Common - Cation efflux system protein CzcB GOX0972 145 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 58039267 Common - tRNA pseudouridine synthase A GOX0801 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 58039164 Nonpathogen - hypothetical protein GOX0695 4 None None None 58038511 Common - Rare lipoprotein A GOX0020 110 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 58040092 Common - hypothetical protein GOX1659 3 None None None 58039959 Common - Flagellar biosynthetic protein FliQ GOX1525 16 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 58038830 Common - LSU ribosomal protein L17P GOX0355 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 58038836 Common - LSU ribosomal protein L15P GOX0361 216 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 58039488 Nonpathogen flgL flagellar hook-associated protein FlgL GOX1025 2 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 58039980 Common - hypothetical protein GOX1546 25 None None None 58038805 Common - phosphoglyceromutase GOX0330 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 58039313 Common - Predicted Rossmann fold nucleotide-binding protein GOX0847 136 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 58040222 Common - acetyl-CoA carboxylase carboxyltransferase subunit alpha GOX1791 176 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 58038932 Common - Putative oxidoreductase GOX0458 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 58039653 Common - Magnesium and cobalt transport protein CorA GOX1200 150 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 58039241 Common - hypothetical protein GOX0775 6 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 58038640 Common - Phospho-N-acetylmuramoyl-pentapeptide-transferase GOX0155 214 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 58040808 Common - DNA integration/recombination/invertion protein GOX2385 169 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 58039248 Common - Transcriptional regulator, TetR family GOX0782 107 COG1309 AcrR, Transcriptional regulator Transcription 58038965 Common - hypothetical protein GOX0494 15 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 58040706 Common - 2-dehydro-3-deoxyphosphooctonate aldolase GOX2281 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 58040360 Common - Transposase (class III) GOX1930 154 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 58040033 Common - Two component response regulator GOX1600 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 58040689 Common - Exopolyphosphatase GOX2263 179 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 58039459 Common - hypothetical protein GOX0995 5 None None None 58038858 Common - 30S ribosomal protein S7 GOX0383 239 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 58040035 Common - hypothetical protein GOX1602 39 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 58040742 Common - Prophage integrase GOX2318 41 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 58040127 Nonpathogen - hypothetical protein GOX1695 1 None None None 58038656 Common - hypothetical protein GOX0171 11 None None None 58038682 Common - NAD(P)H-flavin oxidoreductase GOX0201 71 COG0778 NfnB, Nitroreductase Energy production and conversion 58039675 Nonpathogen - hypothetical protein GOX1222 2 None None None 58040609 Common - Putative polyol dehydrogenase GOX2181 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 58038655 Common - Pyrazinamidase/nicotinamidase GOX0170 126 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 58038992 Common - Transcriptional regulator LysR family GOX0522 122 COG0583 LysR, Transcriptional regulator Transcription 58040892 Nonpathogen - hypothetical protein GOX2469 1 None None None 58039911 Common - Transposase (class II) GOX1476 37 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 58040868 Common - Putative phage-related protein GOX2445 2 None None None 58040062 Common - hypothetical protein GOX1629 54 COG2862 COG2862, Predicted membrane protein Function unknown 58040617 Common - Transposase (class I) GOX2189 57 None None None 58038676 Common rplS 50S ribosomal protein L19 GOX0194 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 58038900 Common - Basal-body rod modification protein FlgD GOX0425 68 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 58039366 Common - hypothetical protein GOX0902 63 COG2351 COG2351, Transthyretin-like protein General function prediction only 58038766 Common - Putative ferredoxin subunit of ring-hydroxylating dioxygenase GOX0291 89 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 58039575 Common - ABC transporter substrate binding protein GOX1115 98 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 58039501 Common - Septum formation associated protein (Maf-like protein) GOX1038 149 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 58039286 Common - GrpE protein (HSP-70 cofactor) GOX0820 210 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 58039699 Common - TonB-dependent receptor protein GOX1246 84 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 58039595 Common - hypothetical protein GOX1136 180 COG1496 COG1496, Uncharacterized conserved protein Function unknown 58040554 Common - ABC transporter ATP-binding protein GOX2126 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 58039005 Common - hypothetical protein GOX0535 90 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 58040026 Common - Nucleoside hydrolase GOX1593 81 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 58040143 Common - Transcriptional regulator GOX1711 176 COG0583 LysR, Transcriptional regulator Transcription 58039900 Common - Transcriptional regulator GOX1459 129 COG1678 COG1678, Putative transcriptional regulator Transcription 58039249 Common - Multidrug resistance protein B GOX0783 222 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 58040560 Nonpathogen - hypothetical protein GOX2132 2 None None None 58038544 Common - Transcription-repair coupling factor GOX0055 221 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 58039384 Common - Phosphate-binding periplasmic protein precursor GOX0920 107 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 58040070 Common - hypothetical protein GOX1637 15 None None None 58040122 Common - Cell cycle protein MesJ GOX1690 204 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 58039817 Nonpathogen - hypothetical protein GOX1373 1 None None None 58039931 Common - Transmembrane transport protein GOX1496 17 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 58040693 Common - Na(+)/H(+) antiporter GOX2268 113 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 58039925 Common - Putative glycosyltransferase GOX1490 18 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 58040016 Common rbfA ribosome-binding factor A GOX1583 151 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 58040246 Common - Phosphatidate cytidylyltransferase GOX1815 212 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 58040907 Nonpathogen - hypothetical protein GOX2484 1 None None None 58039233 Common - hypothetical protein GOX0767 13 COG2365 COG2365, Protein tyrosine/serine phosphatase Signal transduction mechanisms 58040763 Common - Bacteriophage capsid structural protein GOX2339 33 COG5511 COG5511, Bacteriophage capsid protein General function prediction only 58038566 Common - Lipoprotein releasing system ATP-binding protein GOX0077 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 58039076 Common - Methionine aminopeptidase GOX0606 247 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 58040752 Nonpathogen - hypothetical protein GOX2328 1 None None None 58040002 Common - Tricorn protease homolog GOX1569 82 COG4946 COG4946, Uncharacterized protein related to the periplasmic component of the Tol biopolymer transport system Function unknown 58040835 Common - ATP-dependent DNA helicase RecQ GOX2412 239 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 58040859 Common - Endonuclease GOX2436 42 COG1864 NUC1, DNA/RNA endonuclease G, NUC1 Nucleotide transport and metabolism 58039522 Common - DNA integration/recombination/invertion protein GOX1060 134 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 58039708 Nonpathogen - Putative permease GOX1255 1 None None None 58038494 Common recF recombination protein F GOX0003 165 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 58040275 Common - hypothetical protein GOX1844 10 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 58039878 Common - Adenosine deaminase GOX1436 70 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 58040627 Common - probable myosin-crossreactive antigen GOX2200 25 COG4716 COG4716, Myosin-crossreactive antigen Function unknown 58038623 Common - Hypothetical membrane-spanning protein GOX0137 45 COG1289 COG1289, Predicted membrane protein Function unknown 58039590 Common - Pyrroline-5-carboxylate reductase GOX1131 205 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 58039610 Common - hypothetical protein GOX1151 12 COG3942 COG3942, Surface antigen General function prediction only 58040328 Nonpathogen - hypothetical protein GOX1898 1 None None None 58039452 Common - hypothetical protein GOX0988 167 COG0628 PerM, Predicted permease General function prediction only 58039125 Common - Oligopeptide ABC transporter ATP-binding protein OppD GOX0656 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 58038862 Common rplL 50S ribosomal protein L7/L12 GOX0387 215 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 58040390 Common - Lipopolysaccharide heptosyltransferase GOX1962 100 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 58038518 Nonpathogen - hypothetical protein GOX0028 3 None None None 58039580 Common - Disulfide bond formation protein B GOX1120 24 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 58038740 Common - Membrane-bound glucose dehydrogenase (PQQ) GOX0265 58 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 58039785 Common - TonB-dependent outer membrane receptor GOX1341 23 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 58040412 Common - Tetraacyldisaccharide 4'-kinase GOX1984 126 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 58038533 Common - hypothetical protein GOX0043 11 None None None 58040319 Common - Cytochrome c peroxidase GOX1889 94 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 58039601 Common - peptidyl-tRNA hydrolase GOX1142 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 58039284 Common - Sensor protein ChvG GOX0818 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 58039529 Common - Alcohol dehydrogenase large subunit GOX1068 76 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 58039952 Common - aminotransferase GOX1518 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 58040542 Common - Transcriptional regulator GOX2114 78 COG1846 MarR, Transcriptional regulators Transcription 58038918 Common - Molybdopterin (MPT) converting factor, subunit 2 GOX0443 158 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 58040426 Common pyrE orotate phosphoribosyltransferase GOX1998 116 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 58039531 Common rho transcription termination factor Rho GOX1070 206 COG1158 Rho, Transcription termination factor Transcription 58039874 Common - NADP-D-sorbitol dehydrogenase GOX1432 90 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 58039295 Common - Two component sensor histidine kinase GOX0829 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 58040587 Common - Putative oxidoreductase GOX2159 32 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 58040646 Common - Ribose ABC transporter, periplasmic binding protein GOX2219 89 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 58040365 Common - DnaA-related protein GOX1935 57 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 58040113 Common - Holliday junction DNA helicase RuvA GOX1681 208 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 58039113 Common - Putative 2,5-diketo-D-gluconic acid reductase GOX0644 166 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 58038911 Common - Biotin carboxyl carrier protein of acetyl-CoA carboxylase GOX0436 171 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 58039493 Common - Transposase (IS12528) GOX1030 64 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 58040855 Nonpathogen - hypothetical protein GOX2432 2 None None None 58038891 Common - Protein-tyrosine phosphatase GOX0416 16 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 58039909 Common - Sugar permease GOX1474 44 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 58039139 Common - Copper resistance protein CopB GOX0670 43 COG3667 PcoB, Uncharacterized protein involved in copper resistance Inorganic ion transport and metabolism 58039057 Common - Membrane-bound aldehyde dehydrogenase, large subunit GOX0587 108 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 58040236 Common - hypothetical protein GOX1805 51 COG1432 COG1432, Uncharacterized conserved protein Function unknown 58038957 Common - Hypothetical HIT-like protein GOX0485 225 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 58040764 Common - Bacteriophage minor capsid protein C GOX2340 163 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 58039174 Common - Phosphate transport system permease protein PstA GOX0705 228 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 58039832 Common - Transposase (C-terminus missing) GOX1388 24 None None None 58039835 Nonpathogen - hypothetical protein GOX1391 1 None None None 58039032 Common - Putative siderophore receptor protein GOX0562 55 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 58039199 Common - hypothetical protein GOX0730 42 COG1289 COG1289, Predicted membrane protein Function unknown 58038959 Nonpathogen - hypothetical protein GOX0488 1 None None None 58039440 Common - Deoxyribodipyrimidine photolyase GOX0976 137 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 58039720 Common pyrB aspartate carbamoyltransferase catalytic subunit GOX1267 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 58039276 Nonpathogen - hypothetical protein GOX0810 1 None None None 58038554 Common - D-3-phosphoglycerate dehydrogenase GOX0065 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 58039060 Nonpathogen - hypothetical protein GOX0590 2 None None None 58039747 Common - C4-dicarboxylate transport protein GOX1294 157 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 58040875 Nonpathogen - hypothetical protein GOX2452 2 None None None 58038578 Common - hypothetical protein GOX0091 10 None None None 58039462 Common - Putative di-haem cytochrome c peroxidase GOX0998 82 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 58038875 Common minC septum formation inhibitor GOX0400 110 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 58040585 Common - ABC transporter ATP-binding protein GOX2157 249 COG4586 COG4586, ABC-type uncharacterized transport system, ATPase component General function prediction only 58038602 Common - fatty acid/phospholipid synthesis protein GOX0116 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 58040870 Nonpathogen - hypothetical protein GOX2447 2 None None None 58039448 Common - Coenzyme PQQ synthesis protein D GOX0984 17 None None None 58038975 Common - Ribosomal large subunit pseudouridine synthase D GOX0505 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 58040214 Common - hypothetical protein GOX1783 5 None None None 58039132 Common - ABC transporter ATP-binding protein GOX0663 246 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 58039842 Common - Phosphotransferase GOX1398 14 COG4706 COG4706, Predicted 3-hydroxylacyl-(acyl carrier protein) dehydratase Lipid metabolism 58038704 Common - hypothetical protein GOX0229 29 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 58039662 Nonpathogen - hypothetical protein GOX1209 1 None None None 58040840 Common - hypothetical protein GOX2417 36 None None None 58040155 Common - DNA polymerase I GOX1724 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 58039722 Common - hypothetical protein GOX1269 20 COG4297 COG4297, Uncharacterized protein containing double-stranded beta helix domain Function unknown 58039688 Common - Heat shock protein HSP33 GOX1235 113 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 58039204 Common - primosome assembly protein PriA GOX0735 213 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 58040832 Common - Transport ATP-binding protein CydD GOX2409 249 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 58039974 Common - fructose-1,6-bisphosphate aldolase GOX1540 47 COG3588 COG3588, Fructose-1,6-bisphosphate aldolase Carbohydrate transport and metabolism 58039948 Common - DNA integration/recombination/invertion protein GOX1513 70 COG0582 XerC, Integrase DNA replication, recombination, and repair 58039538 Common - hypothetical protein GOX1077 18 COG4982 COG4982, 3-oxoacyl- acyl-carrier protein 58038662 Nonpathogen - hypothetical protein GOX0180 5 None None None 58038867 Common - Putative transport transmembrane protein GOX0392 128 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 58040007 Nonpathogen - hypothetical protein GOX1574 2 None None None 58039681 Common - hypothetical protein GOX1228 3 None None None 58040332 Common groEL chaperonin GroEL GOX1902 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 58038687 Common - Transcriptional regulator GOX0206 190 COG0583 LysR, Transcriptional regulator Transcription 58040511 Common - hypothetical protein GOX2083 8 COG2353 COG2353, Uncharacterized conserved protein Function unknown 58040371 Nonpathogen - hypothetical protein GOX1941 1 None None None 58039277 Common - Transcriptional regulator Fur family GOX0811 116 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 58039764 Common - ATP synthase epsilon chain GOX1314 5 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 58038675 Common - isopropylmalate isomerase large subunit GOX0193 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 58039395 Common - Phage shock protein A GOX0931 72 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 58040251 Common - UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase GOX1820 156 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 58039166 Nonpathogen - Flagellar FliL protein GOX0697 10 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 58040785 Nonpathogen - hypothetical protein GOX2361 1 None None None 58040481 Common - hypothetical protein GOX2053 25 COG1409 Icc, Predicted phosphohydrolases General function prediction only 58040349 Common - Transcriptional regulator GOX1919 17 COG1846 MarR, Transcriptional regulators Transcription 58040534 Common - Transcriptional regulator GOX2106 166 COG0583 LysR, Transcriptional regulator Transcription 58038775 Common - Organic solvent tolerance protein GOX0300 109 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 58039964 Nonpathogen - hypothetical protein GOX1530 1 None None None 58039427 Common - hypothetical protein GOX0963 7 None None None 58039362 Common - guanine deaminase GOX0898 156 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 58038849 Common rpsC 30S ribosomal protein S3 GOX0374 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 58039701 Common - hypothetical protein GOX1248 16 COG3735 COG3735, Uncharacterized protein conserved in bacteria Function unknown 58039626 Common - Outer membrane heme receptor GOX1173 30 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 58038583 Common - ABC transporter permease protein GOX0096 177 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 58039665 Nonpathogen - Phage portal protein GOX1212 4 None None None 58040850 Nonpathogen - hypothetical protein GOX2427 1 None None None 58040725 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase GOX2300 158 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 58038638 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase GOX0153 209 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 58039717 Common - DNA processing chain A GOX1264 209 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 58040703 Common - hypothetical protein GOX2278 12 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 58039413 Common - Putative secreted protein GOX0949 21 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 58039486 Common - Bifunctional protein RfaE (involved in ADP-L-glycero-D-manno-heptose synthesis) GOX1023 152 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 58040751 Nonpathogen - hypothetical protein GOX2327 1 None None None 58040244 Common - Ribosome Recycling Factor (RRF) GOX1813 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 58038741 Common - hypothetical protein GOX0266 2 None None None 58039280 Common - PTS system, IIA component GOX0814 45 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 58040104 Common - O-succinylhomoserine sulfhydrylase GOX1671 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 58039428 Common - ribose-phosphate pyrophosphokinase GOX0964 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 58039307 Common - hypothetical protein GOX0841 4 COG1359 COG1359, Uncharacterized conserved protein Function unknown 58040125 Common - Cell cycle transcriptional regulator CtrA GOX1693 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 58039816 Common - Glutathione S-transferase GOX1372 71 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 58039269 Common - Cell division protein FtsK GOX0803 197 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 58040322 Common - Transposase (class II) GOX1892 42 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 58039485 Common - Transcriptional regulator GOX1022 55 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 58039309 Common - ADP-ribose pyrophosphatase GOX0843 129 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 58038797 Common carB carbamoyl phosphate synthase large subunit GOX0322 236 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 58038681 Common - ATP-dependent RNA helicase GOX0200 238 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 58039329 Common - hypothetical protein GOX0863 106 COG1733 COG1733, Predicted transcriptional regulators Transcription 58040691 Common - tRNA/rRNA cytosine-C5-methylase GOX2266 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 58039344 Common - hypothetical protein GOX0879 6 None None None 58040806 Common gatA aspartyl/glutamyl-tRNA amidotransferase subunit A GOX2383 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 58040479 Common - hypothetical protein GOX2051 68 COG0795 COG0795, Predicted permeases General function prediction only 58040031 Common - Putative oxidoreductase GOX1598 197 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 58038642 Common - Cell division protein FtsW GOX0157 206 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 58038493 Common - DNA polymerase III subunit beta GOX0002 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 58038549 Common smpB SsrA-binding protein GOX0060 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 58040833 Common - Transport ATP-binding protein CydD GOX2410 244 COG4987 CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 58039781 Common - Putative transcriptional regulator GOX1337 190 COG0583 LysR, Transcriptional regulator Transcription 58040845 Nonpathogen - hypothetical protein GOX2422 2 None None None 58040862 Nonpathogen - hypothetical protein GOX2439 1 None None None 58038826 Common - Putative outer membrane drug efflux protein GOX0351 134 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 58038588 Common - Putative membrane-spanning protein GOX0101 49 COG2733 COG2733, Predicted membrane protein Function unknown 58039554 Common - hypothetical protein GOX1093 17 COG3042 Hlx, Putative hemolysin General function prediction only 58039638 Common - hypothetical protein GOX1185 7 COG4833 COG4833, Predicted glycosyl hydrolase Carbohydrate transport and metabolism 58039099 Common - Lipopolysaccharide core biosynthesis protein WbcM GOX0630 194 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 58039170 Common - Phosphate regulon sensor protein PhoR GOX0701 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 58038690 Common - hypothetical protein GOX0209 97 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 58040337 Common - hypothetical protein GOX1907 146 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 58038674 Common - 3-Isopropylmalate dehydratase, small subunit GOX0192 210 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 58038990 Common - Secretory lipase GOX0520 22 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 58039652 Common - Putative oxidoreductase GOX1199 54 COG3749 COG3749, Uncharacterized protein conserved in bacteria Function unknown 58040072 Common - hypothetical protein GOX1639 67 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 58040889 Common - hypothetical protein GOX2466 6 COG3750 COG3750, Uncharacterized protein conserved in bacteria Function unknown 58039374 Common - Transposase (class I) GOX0910 57 None None None 58040012 Common - Hypothetical protein associated with nus operon GOX1579 162 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 161898746 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase GOX1831 140 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 58038967 Common - hypothetical protein GOX0496 89 COG2374 COG2374, Predicted extracellular nuclease General function prediction only 58039759 Common - hypothetical protein GOX1309 8 None None None 58040166 Nonpathogen - hypothetical protein GOX1735 1 COG3133 SlyB, Outer membrane lipoprotein Cell envelope biogenesis, outer membrane 58039042 Common - Putative oxidoreductase GOX0572 104 COG3453 COG3453, Uncharacterized protein conserved in bacteria Function unknown 58040381 Common - 5-Methylcytosine-specific restriction enzyme GOX1953 101 COG1403 McrA, Restriction endonuclease Defense mechanisms 58040135 Common - Transketolase GOX1703 221 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 58040435 Common - hypothetical protein GOX2007 133 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 58040699 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GOX2274 200 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 58040369 Common - Putative transmembrane efflux protein GOX1939 122 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 58040221 Common - Integrase/recombinase XerD GOX1790 224 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 58039741 Common - Biopolymer transport ExbD protein GOX1288 125 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 58038724 Common - hypothetical protein GOX0249 103 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 58039312 Common - hypothetical protein GOX0846 28 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 58039684 Common - Gluconate 2-dehydrogenase alpha chain GOX1231 69 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 58040175 Common glyQ glycyl-tRNA synthetase subunit alpha GOX1744 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 58039222 Common - putative ABC transporter ATP-binding protein GOX0753 248 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 58038889 Nonpathogen - hypothetical protein GOX0414 1 None None None 58039140 Nonpathogen - hypothetical protein GOX0671 1 None None None 58039614 Common - UDP-N-acetylglucosamine 4-epimerase GOX1155 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 58038587 Common - Putative membrane-spanning protein GOX0100 23 COG2733 COG2733, Predicted membrane protein Function unknown 58039983 Common - Chemotaxis protein CheX GOX1550 4 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 58039776 Common - Alkyl hydroperoxide reductase subunit C GOX1332 219 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 58039434 Common - Outer membrane channel lipoprotein GOX0970 116 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 58038906 Common - phosphogluconate dehydratase GOX0431 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 58038622 Common - DNA polymerase related protein GOX0136 149 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 58040819 Common - hypothetical protein GOX2396 41 COG3820 COG3820, Uncharacterized protein conserved in bacteria Function unknown 58039976 Common - Putative aluminum resistance protein GOX1542 162 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 58039290 Common - Bacterial protein translation initiation factor 3 (IF-3) GOX0824 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 58039453 Common - Guanylate kinase GOX0989 213 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 58039016 Common - hypothetical protein GOX0546 40 COG4102 COG4102, Uncharacterized protein conserved in bacteria Function unknown 58040733 Common - delta-aminolevulinic acid dehydratase GOX2308 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 58039584 Common - hypothetical protein GOX1124 13 None None None 58038702 Common - hypothetical protein GOX0227 20 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 58039990 Nonpathogen - hypothetical protein GOX1557 1 None None None 58039059 Common - Lipopolysaccharide core biosynthesis glycosyl transferase GOX0589 209 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 58039004 Common - Putative O-methyltransferase GOX0534 76 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 58040812 Common - Ribosomal protein L11 methyltransferase GOX2389 173 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 58039512 Common - dTDP-4-dehydrorhamnose reductase GOX1050 164 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 58038748 Common - Cell division ATP-binding protein FtsE GOX0273 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 58040285 Common - ABC transporter ATP-binding protein GOX1855 184 COG0661 AarF, Predicted unusual protein kinase General function prediction only 58039737 Common - Penicillin-binding protein 1 (Peptidoglycan synthetase) GOX1284 200 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 58040824 Common - Protein-export membrane protein GOX2401 209 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 58040228 Common - TonB-dependent outer membrane receptor (C-terminal domain) GOX1797 16 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 58040250 Common - hypothetical protein GOX1819 7 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 58040260 Common - acetylglutamate kinase GOX1829 218 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 58039612 Common - Metallo-beta-lactamase superfamily protein GOX1153 186 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 58040261 Common - hypothetical protein GOX1830 17 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 58040277 Common - Capsule expression protein GOX1846 145 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 58039289 Common - Threonyl-tRNA synthetase GOX0823 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 58040770 Common - hypothetical protein GOX2346 2 None None None 58039196 Common - Oligopeptidase B GOX0727 107 COG1770 PtrB, Protease II Amino acid transport and metabolism 58040530 Common - Outer membrane channel protein GOX2102 114 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 58040237 Nonpathogen - hypothetical protein GOX1806 1 None None None 58038851 Common - SSU ribosomal protein S19P GOX0376 243 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 58040267 Common - N-formylmethionylaminoacyl-tRNA deformylase GOX1836 215 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 58039259 Common - Low-specificity threonine aldolase GOX0793 79 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 58040054 Common - Transposase GOX1621 24 None None None 58040747 Nonpathogen - hypothetical protein GOX2323 1 None None None 58038716 Common - GTP-binding protein LepA GOX0241 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 58038878 Common - hypothetical protein GOX0403 26 COG3753 COG3753, Uncharacterized protein conserved in bacteria Function unknown 58040525 Common - Sorbitol dehydrogenase small subunit GOX2097 7 None None None 58040894 Common - Putative transcriptional regulator GOX2471 4 COG1396 HipB, Predicted transcriptional regulators Transcription 58039827 Common - hypothetical protein GOX1383 7 None None None 58039404 Common - hypothetical protein GOX0940 13 None None None 58040174 Common - Glycyl-tRNA synthetase beta chain GOX1743 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 58038861 Common rpoB DNA-directed RNA polymerase subunit beta GOX0386 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 58040589 Common - Transposase (class I) GOX2161 58 None None None 58039918 Common - Capsule polysaccharide export protein GOX1483 66 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 58038758 Common - Phosphatidyserine synthase GOX0283 148 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 58039025 Common - Cation efflux protein GOX0555 121 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 58039215 Common - FAD-dependent monooxygenase GOX0746 135 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 58040397 Common - Uncharacterized PQQ-containing dehydrogenase 2 GOX1969 113 COG1520 COG1520, FOG: WD40-like repeat Function unknown 58040483 Nonpathogen - hypothetical protein GOX2055 12 None None None 58039730 Common - Na(+)/H(+) antiporter GOX1277 65 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 58039788 Nonpathogen - hypothetical protein GOX1344 2 None None None 58039836 Common - hypothetical protein GOX1392 52 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 58040068 Common - Transcriptional regulator GOX1635 156 COG0583 LysR, Transcriptional regulator Transcription 58040637 Common - Transposase (class II) GOX2210 43 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 58038503 Nonpathogen - hypothetical protein GOX0012 1 None None None 58038833 Common rpsM 30S ribosomal protein S13 GOX0358 241 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 58038734 Common - Tryptophanyl-tRNA synthetase GOX0259 220 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 58039352 Common - Phosphopantetheine adenylyltransferase GOX0888 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 58038594 Common - ABC transporter ATP-binding protein GOX0107 249 COG5265 ATM1, ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components Posttranslational modification, protein turnover, chaperones 58039336 Common - Electron transfer flavoprotein alpha-subunit GOX0870 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 58039804 Common - hypothetical protein GOX1360 32 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 58040487 Nonpathogen - hypothetical protein GOX2059 8 COG1887 TagB, Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC Cell envelope biogenesis, outer membrane 58040909 Common - Outer membrane protein TolC GOX2487 74 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 58039924 Common - Putative glycosyltransferase GOX1489 15 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 58040666 Common pdxA 4-hydroxythreonine-4-phosphate dehydrogenase GOX2240 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 58040923 Common - SSU ribosomal protein S20P GOX2501 112 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 58038807 Common - Carboxy-terminal protease GOX0332 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 58038929 Common - Putative transmembrane oxidoreductase GOX0454 45 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 58038811 Common - Poly(A) polymerase/t-RNA nucleotidyltransferase GOX0336 187 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 58039359 Common - hypothetical protein GOX0895 107 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 58039473 Common - Levanase precursor GOX1010 52 COG1621 SacC, Beta-fructosidases (levanase/invertase) Carbohydrate transport and metabolism 58039385 Common - Putative polyphosphate-selective porin O GOX0921 18 COG3746 OprP, Phosphate-selective porin Inorganic ion transport and metabolism 58040219 Common - Bifunctional shikimate kinase GOX1788 214 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 58038699 Common - D-3-phosphoglycerate dehydrogenase GOX0218 229 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 58040916 Common - hypothetical protein GOX2494 30 COG4320 COG4320, Uncharacterized protein conserved in bacteria Function unknown 58040900 Common - hypothetical protein GOX2477 7 None None None 58040437 Common - MiaB protein GOX2009 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 58040445 Common - hypothetical protein GOX2017 55 COG3781 COG3781, Predicted membrane protein Function unknown 58039202 Common - hypothetical protein GOX0733 6 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 58040512 Common - Ribokinase GOX2084 173 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 58040639 Common - hypothetical protein GOX2212 129 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 58039177 Nonpathogen - hypothetical protein GOX0708 1 None None None 58039152 Common - Sensor histidine kinase GOX0683 176 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 58039549 Common ilvH acetolactate synthase 3 regulatory subunit GOX1088 189 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 58039706 Common - D-lactate dehydrogenase GOX1253 51 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 58038778 Common - Cyclopropane-fatty-acyl-phospholipid synthase GOX0303 163 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 58039620 Common hutH histidine ammonia-lyase GOX1167 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 58038631 Nonpathogen - hypothetical protein GOX0146 2 None None None 58040184 Common - Arginyl-tRNA synthetase GOX1753 248 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 58040346 Common - Heat shock protein GOX1916 56 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 58039349 Common - Ferric enterobactin receptor GOX0885 110 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 58040537 Common - hypothetical protein GOX2109 33 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 58038713 Common - hypothetical protein GOX0238 3 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 58040677 Common - Putative arogenate dehydrogenase / prephenate dehydrogenase GOX2251 170 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 58039721 Common - Glutamyl-tRNA synthetase GOX1268 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 58039279 Common - Phosphocarrier protein HPr GOX0813 139 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 58039884 Nonpathogen - hypothetical protein GOX1442 1 None None None 58039896 Common - ATP-dependent RNA helicase GOX1455 236 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 58039881 Common - Queuine tRNA-ribosyltransferase GOX1439 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 58038647 Common - Cell division protein FtsQ GOX0162 72 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 58040738 Common - Lipopolysaccharide core biosynthesis mannosyltransferase GOX2313 95 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 58039495 Common - Acyl-peptide hydrolase-like protein GOX1032 112 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 58040050 Common - hypothetical protein GOX1617 126 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 58040723 Nonpathogen - hypothetical protein GOX2298 1 None None None 58040552 Common - Putative outer membrane protein GOX2124 26 COG3009 COG3009, Uncharacterized protein conserved in bacteria Function unknown 58040241 Common - Ribonuclease III GOX1810 185 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 58040028 Common - Kup system potassium uptake protein GOX1595 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 58039117 Common - Transcriptional regulator LysR family GOX0648 181 COG0583 LysR, Transcriptional regulator Transcription 58040640 Common - hypothetical protein GOX2213 13 None None None 58040516 Common glpD glycerol-3-phosphate dehydrogenase GOX2088 149 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 58038653 Common - NAD-dependent DNA ligase GOX0168 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 58040619 Common - Transposase (class I) GOX2191 57 None None None 58040111 Common - hypothetical protein GOX1679 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 58039667 Nonpathogen - hypothetical protein GOX1214 2 None None None 58039795 Common - Putative isomerase GOX1351 33 COG2942 COG2942, N-acyl-D-glucosamine 2-epimerase Carbohydrate transport and metabolism 58040595 Common - F0F1 ATP synthase subunit beta GOX2167 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 58039640 Common - Myo-inositol 2-dehydrogenase GOX1187 125 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 58038508 Common - DNA polymerase III delta prime subunit DnaC GOX0017 213 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 58040304 Common - Virulence factor MviN GOX1874 192 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 58040447 Common - Putative esterase GOX2019 101 COG0627 COG0627, Predicted esterase General function prediction only 58040373 Common - hypothetical protein GOX1943 28 None None None 58039389 Common - Sugar-proton symporter GOX0925 115 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 58038570 Common - pantothenate kinase GOX0081 139 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 58039442 Common - Bifunctional riboflavin biosynthesis protein RibD GOX0978 207 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 58038955 Common - Imidazole glycerol phosphate synthase subunit HisF GOX0483 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 58039866 Common - O-antigene export system ATP-binding protein GOX1423 246 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 58040872 Nonpathogen - hypothetical protein GOX2449 1 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 58040466 Nonpathogen - hypothetical protein GOX2038 2 None None None 58039089 Nonpathogen - hypothetical protein GOX0619 1 None None None 58039929 Common - Putative oxidoreductase GOX1494 75 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 58040252 Common - (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase GOX1821 186 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 58038658 Common - Hypothetical membrane-spanning protein GOX0175 124 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 58040495 Common - manganese transport protein MntH GOX2067 100 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 58038922 Common - Molybdopterin biosynthesis MoeA protein GOX0447 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 58040563 Nonpathogen - hypothetical protein GOX2135 1 None None None 58038863 Common - LSU ribosomal protein L10P GOX0388 215 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 58040089 Common - hypothetical protein GOX1656 25 COG3686 COG3686, Predicted membrane protein Function unknown 58040674 Common - hypothetical protein GOX2248 11 COG2044 COG2044, Predicted peroxiredoxins General function prediction only 58039478 Common - TonB-dependent receptor of ferrichrome transport system GOX1015 120 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 58039841 Common - hypothetical protein GOX1397 27 None None None 58039848 Common - hypothetical protein GOX1405 155 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 58039133 Common - Transposase GOX0664 146 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 58039649 Common - hypothetical protein GOX1196 130 COG1959 COG1959, Predicted transcriptional regulator Transcription 58039765 Nonpathogen - hypothetical protein GOX1315 1 None None None 58039544 Nonpathogen - hypothetical protein GOX1083 1 None None None 58040669 Common - hypothetical protein GOX2243 3 None None None 58040541 Common - Putative HlyD-family protein GOX2113 132 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 58039704 Common - hypothetical protein GOX1251 9 None None None 58039236 Common - hypothetical protein GOX0770 74 COG3176 COG3176, Putative hemolysin General function prediction only 58038668 Nonpathogen - hypothetical protein GOX0186 2 None None None 58038945 Common - dihydroorotate dehydrogenase 2 GOX0473 229 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 58040877 Nonpathogen - hypothetical protein GOX2454 2 None None None 58038935 Common - hypothetical protein GOX0461 36 COG4645 COG4645, Uncharacterized protein conserved in bacteria Function unknown 58039946 Nonpathogen - hypothetical protein GOX1511 1 None None None 58038559 Common - Hypothetical membrane-spanning protein GOX0070 7 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 58040613 Common - Periplasmic mannitol/sorbitol binding protein GOX2185 100 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 58039069 Common - hypothetical protein GOX0599 16 COG4530 COG4530, Uncharacterized protein conserved in bacteria Function unknown 58039425 Common - DNA-3-methyladenine glycosylase GOX0961 109 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 58040842 Common - Glucokinase GOX2419 91 COG0837 Glk, Glucokinase Carbohydrate transport and metabolism 58039393 Common - hypothetical protein GOX0929 13 None None None 58039127 Common - Oligopeptide ABC transporter permease protein OppC GOX0658 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 58039749 Common - Transcriptional regulator, LysR family GOX1296 187 COG0583 LysR, Transcriptional regulator Transcription 58039231 Nonpathogen - Methyl-accepting chemotaxis protein GOX0765 1 None None None 58039297 Common - Serine protease GOX0831 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 58039713 Common - Outer membrane protein GOX1260 89 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 58039115 Common - Putative oxidoreductase GOX0646 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 58040921 Common - Ubiquinone/menaquinone biosynthesis methyltransferase GOX2499 205 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 58040710 Common - Peptidyl-prolyl cis-trans isomerase GOX2285 100 None None None 58038879 Common - hypothetical protein GOX0404 15 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 58039526 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA GOX1065 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 58038560 Common - Cardiolipin synthetase GOX0071 151 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 58040314 Common - Putative uroporphyrinogen-III synthase GOX1884 11 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 58038914 Common - t-RNA-processing ribonuclease BN GOX0439 112 COG1295 Rbn, Predicted membrane protein Function unknown 58040014 Common - hypothetical protein GOX1581 41 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 58040396 Common - hypothetical protein GOX1968 5 COG4649 COG4649, Uncharacterized protein conserved in bacteria Function unknown 58038661 Common - LytB protein involved in terpenoid biosynthesis GOX0179 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 58039607 Common nadD nicotinic acid mononucleotide adenyltransferase GOX1148 155 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 161898752 Common obgE GTPase ObgE GOX0141 249 COG0536 Obg, Predicted GTPase General function prediction only 58040884 Nonpathogen - hypothetical protein GOX2461 1 None None None 58039520 Common - hypothetical protein GOX1058 37 COG4643 COG4643, Uncharacterized protein conserved in bacteria Function unknown 58038628 Nonpathogen - hypothetical protein GOX0143 3 None None None 58038806 Common - hypothetical protein GOX0331 39 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 58038539 Common - Cobalt insertion protein CobS GOX0050 61 COG0714 COG0714, MoxR-like ATPases General function prediction only 58039616 Common - Imidazolonepropionase GOX1163 103 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 58039941 Nonpathogen - Putative chromosome segregation SMC protein GOX1506 3 None None None 58039455 Common hisD histidinol dehydrogenase GOX0991 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 58038542 Common - hypothetical protein GOX0053 15 None None None 58040223 Common - Putative competence-damage protein GOX1792 164 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 58040149 Common - Putative oxidoreductase GOX1717 111 COG2081 COG2081, Predicted flavoproteins General function prediction only 58038636 Common - hypothetical protein GOX0151 7 COG5462 COG5462, Predicted secreted (periplasmic) protein Function unknown 58040402 Common - Ribosomal protein L11 methyltransferase GOX1974 28 COG3897 COG3897, Predicted methyltransferase General function prediction only 58039862 Common - hypothetical protein GOX1419 21 COG4333 COG4333, Uncharacterized protein conserved in bacteria Function unknown 58038523 Common hisS histidyl-tRNA synthetase GOX0033 249 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 58040857 Nonpathogen - hypothetical protein GOX2434 1 None None None 58039031 Common - TonB-dependent outer membrane receptor GOX0561 17 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 58039791 Common - TonB-dependent outer membrane receptor GOX1347 43 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 58040593 Common - Transposase (class II) GOX2165 43 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 58039586 Common - hypothetical protein GOX1126 11 COG3754 RgpF, Lipopolysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 58040419 Common - chorismate synthase GOX1991 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 58040578 Common - Low-affinity inorganic phosphate transporter GOX2150 34 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 58038517 Common - Hypothetical membrane-spanning protein GOX0026 64 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 58039858 Common - Di-/tripeptide transporter GOX1415 80 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 58039516 Nonpathogen - hypothetical protein GOX1054 8 None None None 58039573 Common - F0F1 ATP synthase subunit A GOX1113 203 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 58038599 Common - hypothetical protein GOX0113 55 COG0789 SoxR, Predicted transcriptional regulators Transcription 58039961 Common flgC flagellar basal body rod protein FlgC GOX1527 125 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 58040761 Common - hypothetical protein GOX2337 9 None None None 58038960 Nonpathogen - hypothetical protein GOX0489 1 None None None 58039110 Common - Hydroxamate-type ferrisiderophore receptor GOX0641 110 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 58038535 Common lipB lipoyltransferase GOX0046 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 58040061 Common - Protease GOX1628 153 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 58038908 Nonpathogen - hypothetical protein GOX0433 3 None None None 58040133 Common - Ankyrin-like protein GOX1701 107 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 58040546 Common - Putative L-aminopeptidase/D-esterase GOX2118 51 COG3191 DmpA, L-aminopeptidase/D-esterase Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 58039814 Common - Ferredoxin, 2Fe-2S GOX1370 101 COG0633 Fdx, Ferredoxin Energy production and conversion 58040559 Common - hypothetical protein GOX2131 3 None None None 58038795 Common - Transcriptional regulator, AraC family GOX0320 72 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 58040106 Common - hypothetical protein GOX1674 35 COG4340 COG4340, Uncharacterized protein conserved in bacteria Function unknown 58038600 Common - Integration host factor alpha-subunit GOX0114 194 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 58040571 Common - ABC transporter ATP-binding protein GOX2143 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 58040717 Common - Dihydrolipoamide dehydrogenase GOX2292 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 58039957 Common - Flagellar biosynthetic protein FlhB GOX1523 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 58040410 Nonpathogen - hypothetical protein GOX1982 2 None None None 58038621 Common - Transcriptional regulator GOX0135 33 COG4957 COG4957, Predicted transcriptional regulator Transcription 58039270 Common - Ribosomal large subunit pseudouridine synthase A GOX0804 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 58039936 Nonpathogen - hypothetical protein GOX1501 10 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 58040837 Common - hypothetical protein GOX2414 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 58039469 Nonpathogen - hypothetical protein GOX1006 2 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 58039506 Common - ABC transporter substrate binding protein GOX1044 49 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 58038718 Common - hypothetical protein GOX0243 7 COG3230 HemO, Heme oxygenase Inorganic ion transport and metabolism 58039782 Common - Putative permease GOX1338 42 COG0628 PerM, Predicted permease General function prediction only 58039593 Common - ADP-L-glycero-D-manno-heptose-6-epimerase GOX1134 221 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 58040568 Common - Putative permease GOX2140 20 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 58039951 Common - Homoserine dehydrogenase GOX1517 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 58040450 Common - Aminomethyltransferase GOX2022 126 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 58040783 Nonpathogen - hypothetical protein GOX2359 1 None None None 58038567 Common - Lipoprotein releasing system transmembrane protein GOX0078 227 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 58039564 Common - hypothetical protein GOX1103 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 58039072 Common - Recombination protein RecR GOX0602 203 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 58040758 Nonpathogen - hypothetical protein GOX2334 3 None None None 58038973 Common - hypothetical protein GOX0503 23 COG3476 COG3476, Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) Signal transduction mechanisms 58038987 Common - Probable transcriptional regulator GOX0517 74 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 58038969 Common - hypothetical protein GOX0498 148 COG1733 COG1733, Predicted transcriptional regulators Transcription 58039292 Common - hypothetical protein GOX0826 11 COG3011 COG3011, Uncharacterized protein conserved in bacteria Function unknown 58039915 Common - Mannosyltransferase GOX1480 117 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 58038550 Common - Dihydropicolinate synthase GOX0061 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 58040168 Common - Rod shape-determining protein MreB GOX1737 236 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 58039323 Common - Chaperone protein DnaK GOX0857 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 58040157 Common - ABC transporter dipeptide binding protein GOX1726 192 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 58039752 Common - Transcriptional regulator GOX1299 16 None None None 58040714 Common - Pyruvate dehydrogenase E1 component alpha subunit GOX2289 156 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 58040896 Nonpathogen - hypothetical protein GOX2473 1 None None None 58040259 Common - GTPase EngB GOX1828 189 COG0218 COG0218, Predicted GTPase General function prediction only 58039439 Nonpathogen - hypothetical protein GOX0975 1 None None None 58039168 Common - L-asparagine permease GOX0699 171 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 58038887 Common holA DNA polymerase III subunit delta GOX0412 49 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 58039044 Common - Putative peroxiredoxin GOX0574 225 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 58039314 Common - hypothetical protein GOX0848 83 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 58040731 Common - Glutaredoxin GOX2306 126 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 58040611 Common - Probable mannitol/sorbitol ABC transporter ATP-binding protein GOX2183 142 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 58039002 Common - ExbB protein GOX0532 120 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 58040697 Common - Membrane-bound dipeptidase GOX2272 102 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 58039992 Common - 4-Diphosphocytidyl-2-C-methyl-D-erythritol kinase GOX1559 176 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 58038746 Nonpathogen - hypothetical protein GOX0271 2 None None None 58040817 Common - Phosphoribosylaminoimidazole carboxylase, catalytic subunit GOX2394 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 58040226 Common - Bacterial ring hydroxylating dioxygenase alpha subunit GOX1795 92 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 58039483 Common - hypothetical protein GOX1020 20 COG4717 COG4717, Uncharacterized conserved protein Function unknown 58039697 Common - Putative enolase-phosphatase GOX1244 32 COG4229 COG4229, Predicted enolase-phosphatase Energy production and conversion 58039179 Common - Glycosyltransferase GOX0710 50 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 58039676 Nonpathogen - hypothetical protein GOX1223 1 None None None 58039018 Common - hypothetical protein GOX0548 44 COG5267 COG5267, Uncharacterized protein conserved in bacteria Function unknown 58039053 Common - ABC-type Fe3+-siderophore transport system, permease component GOX0583 192 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 58039985 Common - Chemotaxis protein CheA GOX1552 160 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 58038872 Nonpathogen - hypothetical protein GOX0397 1 None None None 58039084 Common - Putative methyltransferase GOX0614 113 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 58038831 Common - DNA-directed RNA polymerase subunit alpha GOX0356 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 58039731 Nonpathogen - hypothetical protein GOX1278 1 None None None 58039432 Common - Transposase (IS12528) GOX0968 64 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 58040137 Common - 6-phosphogluconate dehydrogenase-like protein GOX1705 142 COG1023 Gnd, Predicted 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 58039161 Common - Transcriptional regulator TetR family GOX0692 78 COG1309 AcrR, Transcriptional regulator Transcription 58040096 Common - hypothetical protein GOX1663 31 None None None 58039097 Common - hypothetical protein GOX0628 57 COG3893 COG3893, Inactivated superfamily I helicase DNA replication, recombination, and repair 58040199 Common - Alkylated DNA repair protein AlkB GOX1768 58 COG3145 AlkB, Alkylated DNA repair protein DNA replication, recombination, and repair 58039346 Common - Arylesterase GOX0881 122 COG0657 Aes, Esterase/lipase Lipid metabolism 58040423 Common - hypothetical protein GOX1995 33 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 58038809 Common - Probable (di) nucleoside polyphosphate hydrolase GOX0334 111 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 58040606 Common - TonB-dependent receptor GOX2178 80 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 58040329 Common - Putative oxidoreductase GOX1899 236 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 58039327 Common - Flavohemoprotein GOX0861 120 COG1017 Hmp, Hemoglobin-like flavoprotein Energy production and conversion 58038557 Common - Thiosulfate sulfurtransferase GOX0068 140 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 58040457 Common - Putative porin B precursor outer transmembrane protein GOX2029 15 COG3659 OprB, Carbohydrate-selective porin Cell envelope biogenesis, outer membrane 58039317 Common dcd deoxycytidine triphosphate deaminase GOX0851 149 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 58040557 Common - Putative beta-lactamase GOX2129 149 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 58040255 Common - Lactoylglutathione lyase GOX1824 129 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 58040508 Common - Putative outer membrane protein GOX2080 108 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 58039631 Common - Cobalamin biosynthesis protein CobW GOX1178 126 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 58039508 Common - Metal ABC transport system permease protein GOX1046 106 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 58040343 Common - Cytochrome o ubiquinol oxidase subunit III GOX1913 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 58040339 Common - 2'-5' RNA ligase GOX1909 64 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 58038644 Common murC UDP-N-acetylmuramate--L-alanine ligase GOX0159 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 58040059 Common - Cation efflux system protein GOX1626 213 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 58039387 Common - hypothetical protein GOX0923 17 None None None 58038816 Common - hypothetical protein GOX0341 33 COG5426 COG5426, Uncharacterized membrane protein Function unknown 58039415 Common - hypothetical protein GOX0951 179 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 58039679 Common - hypothetical protein GOX1226 4 COG3299 XkdT, Uncharacterized homolog of phage Mu protein gp47 Function unknown 58040864 Nonpathogen - hypothetical protein GOX2441 1 None None None 58039829 Nonpathogen - hypothetical protein GOX1385 2 None None None 58040123 Common - Cell division protein FtsH GOX1691 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 58040683 Common - hypothetical protein GOX2257 18 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 58040847 Nonpathogen - hypothetical protein GOX2424 1 None None None 58038672 Common - Aspartate aminotransferase A GOX0190 236 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 58040161 Nonpathogen - hypothetical protein GOX1730 2 None None None 58040701 Common - LexA repressor GOX2276 168 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 58039561 Common - hypothetical protein GOX1100 133 COG2860 COG2860, Predicted membrane protein Function unknown 58040280 Nonpathogen - hypothetical protein GOX1850 1 None None None 58039220 Nonpathogen - hypothetical protein GOX0751 1 None None None 58040004 Common - Heme exporter protein A GOX1571 249 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 58039838 Common - Putative fatty acyl CoA synthetase GOX1394 15 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 58038762 Nonpathogen - hypothetical protein GOX0287 1 None None None 58038736 Common pheT phenylalanyl-tRNA synthetase subunit beta GOX0261 219 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 58039806 Common - Two component sensor histidine kinase GOX1362 110 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 58039797 Common - hypothetical protein GOX1353 41 COG5360 COG5360, Uncharacterized protein conserved in bacteria Function unknown 58040066 Nonpathogen - hypothetical protein GOX1633 1 COG3753 COG3753, Uncharacterized protein conserved in bacteria Function unknown 58039081 Nonpathogen - hypothetical protein GOX0611 1 None None None 58039568 Common - hypothetical protein GOX1108 66 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 58040040 Common - Lipopolysaccharide N-acetylglucosaminyltransferase II GOX1607 97 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 58040493 Common - Siroheme synthase GOX2065 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 58039071 Common - short chain dehydrogenase GOX0601 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 58039534 Common - Dihydrolipoamide succinyl transferase (E2) of 2-oxoglutarate dehydrogenase GOX1073 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 58040485 Common - Acyl carrier protein GOX2057 14 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 58040076 Common fumC fumarate hydratase GOX1643 214 COG0114 FumC, Fumarase Energy production and conversion 58039354 Nonpathogen - hypothetical protein GOX0890 1 None None None 58038988 Common - hypothetical protein GOX0518 92 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 58040918 Common - Transport protein GOX2496 31 COG4986 COG4986, ABC-type anion transport system, duplicated permease component Inorganic ion transport and metabolism 58040476 Common - Lipopolysaccharide glycosyl transferase GOX2048 146 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 58039898 Common - hypothetical protein GOX1457 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 58039645 Common - Probable transcriptional regulator GOX1192 158 COG1522 Lrp, Transcriptional regulators Transcription 58039253 Common - Flagellin B GOX0787 47 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 58039026 Common - hypothetical protein GOX0556 10 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 58040192 Nonpathogen - hypothetical protein GOX1761 2 COG1396 HipB, Predicted transcriptional regulators Transcription 58040489 Common - Alanine racemase GOX2061 199 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 58039001 Common - ExbD protein GOX0531 133 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 58038793 Common - hypothetical protein GOX0318 8 None None None 58039262 Common - hypothetical protein GOX0796 10 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 58039338 Common - Levansucrase GOX0873 15 None None None 58038789 Common - Probable alcohol dehydrogenase-like oxidoreductase protein GOX0314 204 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 58038813 Common - MoxR-like protein GOX0338 180 COG0714 COG0714, MoxR-like ATPases General function prediction only 58040660 Common - N-(5'-phosphoribosyl)anthranilate isomerase GOX2234 184 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 58040361 Common - Transposase (class V) GOX1931 39 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 58039903 Common - Putative oxidoreductase GOX1462 203 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 58038722 Common - hypothetical protein GOX0247 5 None None None 58040902 Common - hypothetical protein GOX2479 5 COG4717 COG4717, Uncharacterized conserved protein Function unknown 58040290 Common - Transcription elongation factor GreB GOX1860 183 COG0782 GreA, Transcription elongation factor Transcription 58040757 Nonpathogen - hypothetical protein GOX2333 1 None None None 58038585 Common - cysteine desulfurase activator complex subunit SufB GOX0098 185 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 58040635 Common - Transcriptional activator GOX2208 187 COG0583 LysR, Transcriptional regulator Transcription 58038501 Common - Putative Na+/H+ Antiporter GOX0010 94 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 58040045 Common - GDP-mannose 4,6 dehydratase GOX1612 228 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 58038739 Common - LSU ribosomal protein L35P GOX0264 82 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 58039577 Common - hypothetical protein GOX1117 15 COG4765 COG4765, Uncharacterized protein conserved in bacteria Function unknown 58039378 Common - Putative transport protein GOX0914 118 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 58040886 Nonpathogen - hypothetical protein GOX2463 1 None None None 58040324 Common - SMR/MUTS family protein GOX1894 70 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 58040299 Common - hypothetical protein GOX1869 4 None None None 58039581 Common nadE NAD synthetase GOX1121 189 COG0171 NadE, NAD synthase Coenzyme metabolism 58039300 Common - Putative oxidoreductase GOX0834 60 COG0778 NfnB, Nitroreductase Energy production and conversion 58040852 Common - hypothetical protein GOX2429 4 None None None 58040279 Common - Putative oxidoreductase GOX1849 113 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 58040839 Common - Thiamin-monophosphate kinase GOX2416 191 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 58038853 Common - LSU ribosomal protein L23P GOX0378 207 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 58040235 Nonpathogen - hypothetical protein GOX1804 2 None None None 58039655 Common trpA tryptophan synthase subunit alpha GOX1202 217 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 58038898 Common fliG flagellar motor switch protein G GOX0423 125 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 58040242 Common era GTP-binding protein Era GOX1811 236 COG1159 Era, GTPase General function prediction only 58039778 Common - Amino acid efflux protein GOX1334 116 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 58039287 Common - Lipopolysaccharide core biosynthesis protein GOX0821 107 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 58040822 Common - Large-conductance mechanosensitive channel GOX2399 143 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 58039180 Common - hypothetical protein GOX0711 5 None None None 58040283 Common - Putative lipopolysaccharide modification acyltransferase GOX1853 82 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 58038618 Common - Transcriptional regulator, LysR family GOX0132 173 COG0583 LysR, Transcriptional regulator Transcription 58039966 Common - Gamma-glutamyltranspeptidase GOX1532 81 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 58039209 Common - Putative protease GOX0740 81 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 58040172 Common - Rod shape-determining protein RodA GOX1741 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 58039686 Common - hypothetical protein GOX1233 4 None None None 58040203 Common gltX glutamyl-tRNA synthetase GOX1772 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 58040085 Common - Heme exporter protein C GOX1652 120 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 58039235 Common - Apolipoprotein N-acyltransferase GOX0769 159 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 58038800 Common - Threonine dehydratase GOX0325 207 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 58040745 Nonpathogen - hypothetical protein GOX2321 1 None None None 58038943 Common - Putative 4-hydroxyphenylpyruvate dioxygenase GOX0471 38 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 58039191 Common - Biotin synthesis protein BioC GOX0722 135 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 58040052 Common - Two component sensor histidine kinase GOX1619 99 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 58039172 Common - Phosphate transport system protein PhoU GOX0703 196 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 58040269 Common - hypothetical protein GOX1838 4 None None None 58039106 Common - 7-cyano-7-deazaguanine reductase GOX0637 134 COG0780 COG0780, Enzyme related to GTP cyclohydrolase I General function prediction only 58039971 Common - GTP cyclohydrolase I GOX1537 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 58040781 Common - Bacteriophage tail fiber protein GOX2357 4 None None None 58038949 Common - hypothetical protein GOX0477 131 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 58039905 Common - Glucosamine-6-phosphate deaminase GOX1470 76 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 58040620 Nonpathogen - hypothetical protein GOX2192 1 None None None 58038597 Common - hypothetical protein GOX0110 18 None None None 58040854 Common - hypothetical protein GOX2431 19 COG3299 XkdT, Uncharacterized homolog of phage Mu protein gp47 Function unknown 58039135 Common - Outer membrane receptor for ferric iron uptake GOX0666 78 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 58040302 Common - PII uridylyl-transferase GOX1872 123 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 58038979 Nonpathogen - hypothetical protein GOX0509 1 None None None 58039510 Common - hypothetical protein GOX1048 13 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 58040464 Common - Putative oxidoreductase GOX2036 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 58038700 Common - hypothetical protein GOX0225 81 COG1692 COG1692, Uncharacterized protein conserved in bacteria Function unknown 58040630 Nonpathogen - hypothetical protein GOX2203 1 None None None 58040358 Common - hypothetical protein GOX1928 8 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 58039987 Common - Chemotaxis protein CheR GOX1554 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 58040087 Nonpathogen - hypothetical protein GOX1654 2 None None None 58039968 Nonpathogen - hypothetical protein GOX1534 1 COG5373 COG5373, Predicted membrane protein Function unknown 58039272 Nonpathogen - hypothetical protein GOX0806 7 COG3671 COG3671, Predicted membrane protein Function unknown 58040779 Common - Bacteriophage protein GOX2355 23 COG3299 XkdT, Uncharacterized homolog of phage Mu protein gp47 Function unknown 58039420 Common - Probable transcriptional regulator GOX0956 91 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 58040737 Common - Mannosyltransferase GOX2312 21 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 58040210 Common - Putative LysM domain protein GOX1779 29 None None None 58040879 Nonpathogen - hypothetical protein GOX2456 2 None None None 58038666 Nonpathogen - hypothetical protein GOX0184 7 None None None 58040768 Nonpathogen - hypothetical protein GOX2344 1 None None None 58040468 Common - 3-Oxoacyl-[acyl-carrier protein] reductase GOX2040 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 58040430 Common - Putative phosphatase GOX2002 7 None None None 58039444 Common - 3,4-Dihydroy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II GOX0980 232 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 58039408 Common - hypothetical protein GOX0944 10 None None None 58040452 Common - Putative ABC transport system permease protein GOX2024 77 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 58039670 Nonpathogen - hypothetical protein GOX1217 2 COG4386 COG4386, Mu-like prophage tail sheath protein gpL General function prediction only 58040333 Common - TonB-dependent receptor protein GOX1903 103 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 58039890 Common - hypothetical protein GOX1449 8 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 58038865 Common rplK 50S ribosomal protein L11 GOX0390 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 58038972 Common - Putative oxidoreductase GOX0502 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 58039995 Common - Bacteriophage-type DNA polymerase GOX1562 149 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 58040308 Common - Nucleoside permease GOX1878 68 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 58040874 Nonpathogen - hypothetical protein GOX2451 1 None None None 58039063 Common - Glycosyltransferase GOX0593 123 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 58038771 Common - hypothetical protein GOX0296 235 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 58038577 Common - Putative sugar kinase GOX0090 216 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 58039150 Common - Bacteriophage-type DNA helicase GOX0681 47 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 58039229 Common - ATP-dependent protease La GOX0763 36 COG2802 COG2802, Uncharacterized protein, similar to the N-terminal domain of Lon protease General function prediction only 58040721 Common - hypothetical protein GOX2296 193 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 58039711 Common - hypothetical protein GOX1258 5 None None None 58040565 Common - Transcriptional regulator GOX2137 183 COG0583 LysR, Transcriptional regulator Transcription 58040502 Common - 5-Methyltetrahydrofolate-S-homocysteine methyltransferase GOX2074 176 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 58039846 Common - Transposase (class I, C-terminus missing) GOX1402 28 None None None 58040749 Nonpathogen - hypothetical protein GOX2325 1 None None None 58040439 Common - Outer membrane protein GOX2011 140 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 58039726 Nonpathogen - hypothetical protein GOX1273 1 None None None 58040788 Nonpathogen - hypothetical protein GOX2364 1 None None None 58040310 Common - Glycerol-3-phosphate dehydrogenase [NAD(P)+] GOX1880 210 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 58040443 Common - NAD(P)-dependent glucose 1-dehydrogenase GOX2015 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 58039920 Common - Capsule polysaccharide export inner-membrane protein GOX1485 31 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 58040159 Common - Phosphoribosylamine-glycine ligase GOX1728 234 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 58040729 Common - phosphoribosylformylglycinamidine synthase II GOX2304 233 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 58040514 Nonpathogen - hypothetical protein GOX2086 1 None None None 58039557 Common - Glycine cleavage system H protein GOX1096 179 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 58038495 Common - DNA gyrase subunit B GOX0004 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 58040348 Common - Leucine aminopeptidase GOX1918 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 58038671 Common - Aspartate aminotransferase A GOX0189 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 58038692 Common - hypothetical protein GOX0211 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 58039622 Common - hypothetical protein GOX1169 30 COG3758 COG3758, Uncharacterized protein conserved in bacteria Function unknown 58040539 Nonpathogen - hypothetical protein GOX2111 2 None None None 58040387 Common - Shikimate 5-dehydrogenase GOX1959 222 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 58040292 Common - Phosphatidylethanolamine N-methyltransferase GOX1862 196 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 58039723 Common - Transposase GOX1270 51 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 58038896 Common - flagellar motor switch protein GOX0421 125 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 58039939 Common - ATP-dependent helicase HepA GOX1504 134 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 58039119 Common - hypothetical protein GOX0650 14 None None None 58040844 Nonpathogen - hypothetical protein GOX2421 1 None None None 58040518 Common - Glycerol kinase GOX2090 178 COG0554 GlpK, Glycerol kinase Energy production and conversion 58040591 Common - Cold shock protein GOX2163 178 COG1278 CspC, Cold shock proteins Transcription 58040521 Nonpathogen - hypothetical protein GOX2093 1 None None None 58038845 Common - LSU ribosomal protein L14P GOX0370 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 58040021 Common - hypothetical protein GOX1588 24 COG1289 COG1289, Predicted membrane protein Function unknown 58038649 Common - cell division protein FtsZ GOX0164 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 58040309 Common - Superoxide dismutase [Cu-Zn] GOX1879 86 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 58039888 Common - Histidyl-tRNA synthetase GOX1447 198 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 58040791 Common - SOS (error prone) mutagenesis protein UmuC GOX2367 181 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 58039461 Common - hypothetical protein GOX0997 4 None None None 58039273 Common - hypothetical protein GOX0807 5 COG3671 COG3671, Predicted membrane protein Function unknown 58039819 Common - Gluconolactonase GOX1375 46 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 58040655 Common thiE thiamine-phosphate pyrophosphorylase GOX2228 200 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 58039633 Common - Putative sugar uptake ABC transporter permease protein GOX1180 153 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 58040150 Common - Pantoate--beta-alanine ligase GOX1718 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 58039369 Common - Putative oxidoreductase GOX0905 26 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 58039380 Common - hypothetical protein GOX0916 61 COG3391 COG3391, Uncharacterized conserved protein Function unknown 58040100 Nonpathogen - hypothetical protein GOX1667 1 None None None 58040798 Nonpathogen - hypothetical protein GOX2374 1 None None None 58039692 Common - hypothetical protein GOX1239 13 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 58038820 Common - Ribonuclease HII GOX0345 206 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 58038780 Common rpsR 30S ribosomal protein S18 GOX0305 215 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 58039934 Common - hypothetical protein GOX1499 18 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 58039112 Common - hypothetical protein GOX0643 9 None None None 58040200 Common - 2-Dehydro-3-deoxyphosphoheptonate aldolase GOX1769 73 COG3200 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 58038650 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase GOX0165 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 58039391 Common - sulfate adenylyltransferase subunit 2 GOX0927 130 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 58040506 Common - hypothetical protein GOX2078 7 COG4502 COG4502, Uncharacterized protein conserved in bacteria Function unknown 58038729 Common - Putative Fe-S-cluster redox enzyme GOX0254 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 58040550 Common - Dipeptide ABC transport system permease protein DppB GOX2122 218 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 58039571 Common - ATP synthase B' chain GOX1111 35 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 58040209 Common - Putative transmembrane efflux protein GOX1778 157 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 58038904 Common - Hypothetical membrane-spanning protein GOX0429 25 COG1988 COG1988, Predicted membrane-bound metal-dependent hydrolases General function prediction only 58039108 Common - hypothetical protein GOX0639 11 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 58040672 Nonpathogen - hypothetical protein GOX2246 2 None None None 58040573 Common - hypothetical protein GOX2145 156 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 58038635 Common - SAM-dependent methytransferase GOX0150 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 58039010 Nonpathogen - hypothetical protein GOX0540 2 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 58039767 Common - Transposase GOX1323 94 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 58040684 Common - Putative phytoene synthase GOX2258 102 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 58038515 Common uppP undecaprenyl pyrophosphate phosphatase GOX0024 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 58040375 Common - Putative protease GOX1945 20 COG3591 COG3591, V8-like Glu-specific endopeptidase Amino acid transport and metabolism 58040849 Common - Transposase (IS12528) GOX2426 64 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 58039467 Common - Septum formation associated protein (Maf-like protein) GOX1003 140 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 58039758 Common - Protein translocase subunit SecE GOX1306 40 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 58039591 Common - hypothetical protein GOX1132 34 COG5465 COG5465, Uncharacterized conserved protein Function unknown 58039218 Common - Putative lipoprotein GOX0749 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 58040181 Common - Exodeoxyribonuclease III GOX1750 195 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 58039120 Common - hypothetical protein GOX0651 22 COG5368 COG5368, Uncharacterized protein conserved in bacteria Function unknown 58040394 Common - hypothetical protein GOX1966 5 None None None 58040403 Common - 4-Hydroxybenzoate octaprenyltransferase GOX1975 124 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 58039038 Common - hypothetical protein GOX0568 3 None None None 58039955 Common - hypothetical protein GOX1521 8 None None None 58038569 Common - Metal-dependent hydrolase GOX0080 152 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 58038989 Common - Hypothetical outer membrane protein GOX0519 111 None None None 58039917 Common - Glycosyltransferase GOX1482 124 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 58038937 Common - NrfA protein GOX0465 125 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 58039618 Common - N-formylglutamate deformylase GOX1165 56 COG3741 HutG, N-formylglutamate amidohydrolase Amino acid transport and metabolism 58040147 Common - TonB-dependent receptor protein GOX1715 18 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 58040417 Common - hypothetical protein GOX1989 8 None None None 58039504 Common - Putative transcriptional regulator GOX1042 113 COG2606 EbsC, Uncharacterized conserved protein Function unknown 58038562 Common - DNA topoisomerase IV subunit A GOX0073 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 58038615 Common - Dolichol-phosphate mannosyltransferase GOX0129 158 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 58039546 Common - Phosphoserine phosphatase GOX1085 153 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 58040107 Common - NADH dehydrogenase type II GOX1675 179 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 58039299 Common - Cold shock protein GOX0833 179 COG1278 CspC, Cold shock proteins Transcription 58038711 Common - Protein Translation Elongation Factor P (EF-P) GOX0236 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 58040316 Common - Putative translocase transmembrane protein GOX1886 36 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 58038609 Common - Polypeptide deformylase GOX0123 213 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 58038528 Common - 3-demethylubiquinone-9 3-methyltransferase GOX0038 116 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 58039605 Common - translation-associated GTPase GOX1146 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 58039157 Common - Putative efflux protein GOX0688 29 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 58038874 Common - Glutathione S-transferase GOX0399 69 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 58038916 Common - Molybdenum-pterin binding protein GOX0441 65 COG3585 MopI, Molybdopterin-binding protein Coenzyme metabolism 58039793 Common - Putative transporter GOX1349 132 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 58038574 Common clpX ATP-dependent protease ATP-binding subunit GOX0086 226 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 58038521 Nonpathogen - hypothetical protein GOX0031 2 None None None 58039743 Common - hypothetical protein GOX1290 9 None None None 58040421 Common - ribonucleotide-diphosphate reductase subunit alpha GOX1993 221 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 58039851 Common - Binding protein component of ABC transporter GOX1408 31 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 58040084 Common - cytochrome c-type biogenesis protein CcmE GOX1651 95 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 58039864 Common - Murein transglycosylase GOX1421 116 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 58040074 Common - Bacteriophytochrome protein GOX1641 99 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 58039129 Common - Cysteine synthase GOX0660 224 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 58040716 Common - Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase GOX2291 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 58038931 Common - hypothetical protein GOX0456 79 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 58039642 Common - hypothetical protein GOX1189 6 None None None 58039860 Common - Ferrichrome receptor FcuA GOX1417 83 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 58040142 Common - hypothetical protein GOX1710 96 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 58039087 Common - hypothetical protein GOX0617 89 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 58040580 Common - hypothetical protein GOX2152 53 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 58039040 Nonpathogen - hypothetical protein GOX0570 1 None None None 58039524 Common - Chromosome partitioning protein ParA GOX1063 233 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 58040118 Common - hypothetical protein GOX1686 4 COG5373 COG5373, Predicted membrane protein Function unknown