Idiomarina loihiensis L2TR, complete genome NC_006512 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 56461028 Common - tRNA-dihydrouridine synthase A IL1928 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 56460601 Common - hypothetical protein IL1495 9 None None None 56459655 Common - hypothetical protein IL0546 2 None None None 56459269 Common csgE Curli production assembly/transport component, CsgE IL0158 5 None None None 56459557 Common mutT 7,8-dihydro-8-oxoguanine-triphosphatase IL0446 173 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 56459725 Common argH bifunctional argininosuccinate lyase/N-acetylglutamate synthase IL0616 225 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 56460549 Common - Signaling protein with a ligand-binding sensor domain and GGDEF domain IL1441 183 COG3292 COG3292, Predicted periplasmic ligand-binding sensor domain Signal transduction mechanisms 56459526 Common rpsI Ribosomal protein S9 IL0415 248 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 56459199 Common - Alkaline phosphatase superfamily protein IL0088 61 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 56459737 Common - Transcription elongation factor greA/greB family IL0628 4 COG0782 GreA, Transcription elongation factor Transcription 56459448 Common purA Adenylosuccinate synthase IL0337 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 56459356 Common mutM Formamidopyrimidine DNA glycosylase IL0245 181 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 56460988 Common - hypothetical protein IL1888 105 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 56459740 Common soxR_1 Transcriptional regulator, MerR family IL0631 137 COG0789 SoxR, Predicted transcriptional regulators Transcription 56459785 Common cspD Cold shock protein IL0676 178 COG1278 CspC, Cold shock proteins Transcription 56460244 Common fliC Flagellin IL1136 122 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 56460934 Common hisG ATP phosphoribosyltransferase IL1834 207 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 56461445 Common - hypothetical protein IL2345 6 None None None 56460391 Common - Thioredoxin related protein IL1283 8 None None None 56459134 Common - Possible translation factor, Sua5/YciO/YrdC/YwlC family IL0022 238 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 56460404 Common - Methyl-accepting chemotaxis protein IL1296 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 56460815 Common rsbV Anti-anti-sigma regulatory factor IL1714 25 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 56461063 Common - Acyl-CoA dehydrogenase family protein IL1963 150 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 56460962 Common - hypothetical protein IL1862 12 None None None 56460262 Common - hypothetical protein IL1154 10 None None None 56461385 Common accB Acetyl-CoA carboxylase, biotin carboxyl carrier protein IL2285 182 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 56460948 Common - hypothetical protein IL1848 176 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 56461301 Common dnaG DNA primase IL2201 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 56459304 Common - Collagenase family protease IL0193 46 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 56459854 Common rpoS DNA-directed RNA polymerase sigma 38 subunit IL0745 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 56461589 Common - Outer membrane phospholipase A IL2489 52 COG2829 PldA, Outer membrane phospholipase A Cell envelope biogenesis, outer membrane 56459692 Common - Oar-like outer membrane protein protein, OmpA family IL0583 23 None None None 56461459 Common fre FMN reductase IL2359 106 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 56460253 Common flgD flagellar basal body rod modification protein IL1145 97 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 56459842 Common dppA ABC-type dipeptide transport system, periplasmic component IL0733 209 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 56461701 Nonpathogen - hypothetical protein IL2601 1 None None None 56461222 Common - Predicted signal transduction protein IL2122 48 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 56461237 Common ispA_2 Geranylgeranyl pyrophosphate synthase IL2137 241 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 56460588 Common - Allophanate hydrolase subunit 1 IL1480 102 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 56460258 Common flgA flagellar basal body P-ring biosynthesis protein FlgA IL1150 51 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 56459735 Common - hypothetical protein IL0626 106 COG2855 COG2855, Predicted membrane protein Function unknown 56461579 Common - Predicted flavoprotein IL2479 136 COG2081 COG2081, Predicted flavoproteins General function prediction only 56461463 Common rhlB ATP-dependent RNA helicase RhlB IL2363 232 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 56460985 Nonpathogen - hypothetical protein IL1885 1 None None None 56460954 Common - TPR repeats containing protein IL1854 19 None None None 56460398 Common - Transcriptional regulator, HTH motif containing IL1290 14 COG3905 COG3905, Predicted transcriptional regulator Transcription 56459279 Common - Outer membrane protein IL0168 73 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 56459406 Common - Regulator of cell autolysis (HATPase) IL0295 103 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 56460826 Common rimM 16S rRNA-processing protein IL1725 196 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 56460113 Common clpP Protease subunit of ATP-dependent Clp protease IL1005 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 56459129 Common fmt Methionyl-tRNA formyltransferase IL0017 219 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 56460107 Common - Uncharacterized protein containing a von Willebrand factor type A (vWA) domain and TPR repeats IL0999 46 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 56460068 Common lipA lipoyl synthase IL0960 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 56460931 Common - Inactive metal-dependent protease-like protein IL1831 196 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 56459719 Common trg Methyl-accepting chemotaxis protein (contains HAMP domain) IL0610 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 56460315 Common - Predicted metal-dependent amidohydrolase with the TIM-barrel fold IL1207 114 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 56460334 Common - Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF IL1226 162 COG2871 NqrF, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF Energy production and conversion 56461259 Common - hypothetical protein IL2159 6 None None None 56460769 Common ushA 5'-nucleotidase IL1668 135 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 56461492 Common - Probable secreted protein containing HslJ-like protein IL2392 17 COG3187 HslJ, Heat shock protein Posttranslational modification, protein turnover, chaperones 56461593 Common cspE Cold shock protein IL2493 180 COG1278 CspC, Cold shock proteins Transcription 56459862 Common ftsB Septum formation initiator, FtsB IL0753 63 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 56461272 Common - Methyl-accepting chemotaxis protein IL2172 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 56459120 Common - Acetyltransferase, GNAT family IL0008 62 COG0456 RimI, Acetyltransferases General function prediction only 56460003 Common - Phosphohistidine phosphatase SixA IL0895 58 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 56461200 Common - hypothetical protein IL2100 53 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 56459153 Common appC Cytochrome bd-type quinol oxidase, subunit 1 IL0041 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 56461331 Common pdxA Pyridoxal phosphate biosynthesis protein IL2231 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 56459415 Common - Ser/Thr protein phosphatase family protein, calcineurin-like superfamily IL0304 8 None None None 56459542 Common murE UDP-N-acetylmuramyl tripeptide synthase IL0431 215 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 56461125 Common pulE Type II secretory pathway, ATPase PulE-like IL2025 216 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 56460652 Common rhlE ATP-dependent RNA helicase IL1546 237 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 56461322 Common - Predicted PhoH-related ATPase IL2222 198 COG1875 COG1875, Predicted ATPase related to phosphate starvation-inducible protein PhoH Signal transduction mechanisms 56460481 Common - BNR/Asp-box repeat protein IL1373 33 COG4447 COG4447, Uncharacterized protein related to plant photosystem II stability/assembly factor General function prediction only 56461358 Common - ABC-type multidrug transport system, permease component IL2258 176 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 56459118 Common glyQ glycyl-tRNA synthetase subunit alpha IL0006 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 56459763 Common uvrY Response regulator, LuxR family (CheY, HTH domains) IL0654 144 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 56460663 Nonpathogen - Antibiotic biosynthesis monooxygenase family enzyme IL1557 4 None None None 56459147 Common purE Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase IL0035 228 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 161761289 Common fldB flavodoxin FldB IL1024 67 COG0716 FldA, Flavodoxins Energy production and conversion 56459875 Common thiE Thiamine monophosphate synthase IL0766 223 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 56459927 Common - hypothetical protein IL0819 51 COG2938 COG2938, Uncharacterized conserved protein Function unknown 56459493 Common mreC Rod shape-determining protein IL0382 152 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 56460775 Common - Glyoxalase I family protein IL1674 47 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 56460854 Common trpD Anthranilate phosphoribosyltransferase IL1753 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 56459249 Common - FAD-binding protein IL0138 128 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 56460698 Common fecI DNA-directed RNA polymerase specialized sigma subunit IL1594 60 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 56460342 Common copB hypothetical protein IL1234 41 COG3667 PcoB, Uncharacterized protein involved in copper resistance Inorganic ion transport and metabolism 56461179 Common - Protein containing acetyltransferase (GNAT family) domain IL2079 6 None None None 56460366 Common - Aminopeptidase N family protein, contains PDZ domain IL1258 56 COG3975 COG3975, Predicted protease with the C-terminal PDZ domain General function prediction only 56461172 Common - hypothetical protein IL2072 25 COG4283 COG4283, Uncharacterized conserved protein Function unknown 56461250 Common - Probable transcriptional activator of acetoin/glycerol metabolism IL2150 169 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 56459960 Common - hypothetical protein IL0852 9 None None None 56460881 Common - hypothetical protein IL1781 28 COG2859 COG2859, Uncharacterized protein conserved in bacteria Function unknown 56459288 Common acoA Probable oxoisovalerate dehydrogenase alpha and beta subunits IL0177 162 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 56459814 Common - Probable aminopeptidase IL0705 46 COG2234 Iap, Predicted aminopeptidases General function prediction only 56459599 Common - hypothetical protein IL0488 11 None None None 56459516 Common - ABC-type transport system involved in resistance to organic solvents, periplasmic component IL0405 51 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 56460376 Common - Na(+)-linked D-alanine and glycine permease IL1268 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 56460105 Nonpathogen - hypothetical protein IL0997 2 None None None 56459285 Common deoD Purine-nucleoside phosphorylase IL0174 97 COG0813 DeoD, Purine-nucleoside phosphorylase Nucleotide transport and metabolism 56459887 Common czcB Co/Zn/Cd efflux system component IL0778 103 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 56460593 Common - short chain dehydrogenase IL1485 229 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 56461661 Common hemY Uncharacterized enzyme of heme biosynthesis IL2561 43 COG3071 HemY, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 56461688 Common - Outer membrane protein IL2588 115 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 56460424 Common ppsA phosphoenolpyruvate synthase IL1316 237 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 56460998 Common rpmD 50S ribosomal protein L30 IL1898 145 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 56459332 Common - Predicted dioxygenase of extradiol dioxygenase family IL0221 34 COG3565 COG3565, Predicted dioxygenase of extradiol dioxygenase family General function prediction only 56459477 Nonpathogen mshK Type II secretory pathway component IL0366 2 None None None 56461119 Common pulK Type II secretory pathway, component PulK IL2019 35 COG3156 PulK, Type II secretory pathway, component PulK Intracellular trafficking and secretion 56460344 Common - Sec-independent protein secretion pathway component, TatA family IL1236 21 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 56460839 Common alaS Alanyl-tRNA synthetase IL1738 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 56459618 Common thyA thymidylate synthase IL0507 136 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 56460475 Common hrpA Helicase, ATP-dependent IL1367 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 56460991 Common rpoA DNA-directed RNA polymerase subunit alpha IL1891 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 56460675 Common - 2-hydroxyacid dehydrogenase IL1569 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 56461217 Common - TonB system biopolymer transport component IL2117 67 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 56461481 Common rpoZ DNA-directed RNA polymerase subunit omega IL2381 118 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 56461572 Common aroK Shikimate kinase IL2472 200 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 56461043 Common vacB Exoribonuclease R IL1943 195 COG0557 VacB, Exoribonuclease R Transcription 56461452 Common dps_2 Ferritin-like DNA-binding protein IL2352 131 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 56461000 Common rplR 50S ribosomal protein L18 IL1900 207 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 56461609 Common - RRNA (guanine-N1-)-methyltransferase, putative IL2509 75 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 56460387 Common - NAD-specific glutamate dehydrogenase IL1279 77 COG2902 COG2902, NAD-specific glutamate dehydrogenase Amino acid transport and metabolism 56460941 Common hisI Phosphoribosyl-AMP cyclohydrolase IL1841 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 56460716 Nonpathogen - Predicted secreted protein IL1612 1 None None None 56459837 Common - Predicted ATPase IL0728 42 COG3106 COG3106, Predicted ATPase General function prediction only 56461423 Common trpS tryptophanyl-tRNA synthetase IL2323 224 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 56459920 Common lepA GTP-binding protein LepA IL0812 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 56461507 Common - Acetyltransferase, GNAT family IL2407 16 COG0456 RimI, Acetyltransferases General function prediction only 56459485 Common mshA Type II secretory pathway, pseudopilin IL0374 9 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 56460061 Common mrdA Cell division protein FtsI IL0953 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 56459455 Common rplL 50S ribosomal protein L7/L12 IL0344 211 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 56461292 Common - NAD(P)H oxidoreductase IL2192 61 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 56459775 Common lolA Outer membrane lipoprotein-sorting protein IL0666 52 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 56461556 Common - Signaling protein with DMT-family integral membrane sensor domain, GGDEF and EAL domains IL2456 175 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 56461135 Common - Predicted transcriptional regulator, contains N-terminal xre-type HTH domain IL2035 83 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 56460468 Common gyrA DNA gyrase subunit A IL1360 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 56459592 Common natA_2 ABC-type Na+ transport system, ATPase component IL0481 249 COG4555 NatA, ABC-type Na+ transport system, ATPase component Energy production and conversion / Inorganic ion transport and metabolism 56459637 Common - Transcriptional regulator, Cro/CI/xre family IL0527 9 None None None 56461219 Common - TonB system biopolymer transport component IL2119 18 None None None 56460444 Common tmk Thymidylate kinase IL1336 228 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 56460724 Common - hypothetical protein IL1621 6 None None None 56459270 Common - Uncharacterized conserved secreted protein with internal repeats IL0159 26 None None None 56461141 Common - Predicted transcriptional regulator, YjeB/RRF2 family IL2041 174 COG1959 COG1959, Predicted transcriptional regulator Transcription 56460546 Nonpathogen - hypothetical protein IL1438 1 None None None 56459678 Common - Membrane-associated enzyme of epimerase/dehydratase family, wbfY-like protein IL0569 169 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 56461615 Common - hypothetical protein IL2515 67 COG1636 COG1636, Uncharacterized protein conserved in bacteria Function unknown 56460297 Common fliQ Flagellar biosynthesis protein FliQ IL1189 119 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 56461620 Common higB RelE/ParE family protein, cytotoxic translational repressor of toxin-antitoxin stability system IL2520 56 COG3549 HigB, Plasmid maintenance system killer protein General function prediction only 56459205 Common - TPR repeats containing protein IL0094 19 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 56461537 Common glnA glutamine synthetase IL2437 228 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 56460804 Common cysZ putative sulfate transport protein CysZ IL1703 39 COG2981 CysZ, Uncharacterized protein involved in cysteine biosynthesis Amino acid transport and metabolism 56461021 Common rplB 50S ribosomal protein L2 IL1921 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 56460165 Common pqiA Paraquat-inducible membrane protein A IL1057 55 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 56460638 Common - IS4-like transposase IL1532 27 COG3385 COG3385, FOG: Transposase and inactivated derivatives DNA replication, recombination, and repair 56459710 Common - RND family efflux system membrane fusion protein IL0601 157 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 56459457 Common rpoC DNA-directed RNA polymerase subunit beta' IL0346 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 56459804 Common - Secreted protein containing N-terminal Zinc-dependent carboxypeptidase related domain IL0695 12 None None None 56459181 Common ada O6-methylguanine-DNA methyltransferase IL0070 162 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 56461411 Common slyX Uncharacterized conserved protein SlyX IL2311 37 COG2900 SlyX, Uncharacterized protein conserved in bacteria Function unknown 56459483 Common - Predicted Type II secretory pathway component IL0372 3 None None None 56460689 Common - Alpha/beta superfamily hydrolase IL1585 10 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 56460418 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase IL1310 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 56459378 Common glpG Membrane serine peptidase IL0267 43 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 56460493 Common - Predicted NAD/FAD-binding protein IL1385 73 COG2907 COG2907, Predicted NAD/FAD-binding protein General function prediction only 56461199 Common - hypothetical protein IL2099 42 COG3079 COG3079, Uncharacterized protein conserved in bacteria Function unknown 56461530 Common - Predicted rRNA/tRNA methylase, SpoU family IL2430 160 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 56460792 Common dcp Zn-dependent oligopeptidase IL1691 123 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 56461235 Common motA flagellar motor protein PomA IL2135 93 COG1291 MotA, Flagellar motor component Cell motility and secretion 56459827 Common - Dipeptidyl peptidase IV IL0718 109 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 56460591 Nonpathogen - Predicted membrane protein IL1483 1 None None None 56459339 Common ftsX Cell division protein FtsX IL0228 115 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 56460274 Common - hypothetical protein IL1166 6 None None None 56460514 Common - Secreted metal-dependent enzyme of cyclase family IL1406 33 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 56461566 Common metL bifunctional aspartate kinase II/homoserine dehydrogenase II IL2466 236 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 56459432 Common envZ osmolarity sensor protein IL0321 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 56460022 Common exsB Predicted PP-loop superfamily ATPase IL0914 177 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 56460188 Common tolB Periplasmic component of the Tol biopolymer transport system IL1080 152 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 56459577 Common - RND efflux system membrane fusion protein IL0466 165 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 56460393 Common - Uncharacterized conserved secreted or membrane protein IL1285 5 COG3384 COG3384, Uncharacterized conserved protein Function unknown 56461466 Common - Signaling protein with a acyltransferase and GGDEF domains IL2366 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 56459788 Common intE Integrase IL0679 16 None None None 56460575 Common - hypothetical protein IL1467 8 COG3308 COG3308, Predicted membrane protein Function unknown 56460861 Common - hypothetical protein IL1760 58 COG3174 COG3174, Predicted membrane protein Function unknown 56459839 Common pspB phage shock protein B IL0730 23 None None None 56461327 Common - Nucleoside-diphosphate-sugar pyrophosphorylase IL2227 220 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 56460608 Common sucB 2-oxoglutarate dehydrogenase IL1502 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 56461161 Common - Response regulator, contains CheY-like receiver, AAA-type ATPase and DNA-binding domains IL2061 213 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 56460126 Common fimV Probable Tfp pilus assembly protein FimV , contains LysM domain IL1018 21 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 56460432 Common bioB Biotin synthase IL1324 182 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 56461699 Common - hypothetical protein IL2599 2 None None None 56459676 Common - WbfD-like uncharacterized domain involved in polysaccharide synthesis IL0567 13 None None None 56461089 Common - Protein related to deoxyribodipyrimidine photolyase IL1989 59 COG3046 COG3046, Uncharacterized protein related to deoxyribodipyrimidine photolyase General function prediction only 56461627 Common vsr DNA mismatch endonuclease, patch repair protein IL2527 71 COG3727 Vsr, DNA G:T-mismatch repair endonuclease DNA replication, recombination, and repair 56459318 Common rep Rep helicase, a single-stranded DNA dependent ATPase IL0207 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 56459169 Common hipB Transcriptional regulator, HipB ortholog IL0058 8 None None None 56461170 Common - Antitoxin of toxin-antitoxin stability system, StbD family IL2070 27 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 56461190 Nonpathogen - Predicted membrane protein IL2090 1 None None None 56459539 Common mraW S-adenosyl-methyltransferase MraW IL0428 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 56460749 Common - Response regulator (CheY, wHTH domains) IL1648 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 56461078 Common - potassium/proton antiporter IL1978 157 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 56459934 Common xerD Site-specific recombinase IL0826 232 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 56460784 Common - RND family efflux transporter IL1683 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 56459549 Common ddlB D-alanine-D-alanine ligase B IL0438 212 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 56460842 Common - Signaling protein with TPR repeats and GGDEF domain IL1741 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 56460797 Common - SAM-dependent methyltransferase IL1696 53 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 56460354 Common - Possible outer membrane lipoprotein IL1246 26 None None None 56461071 Common gatA amidase IL1971 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 56459255 Common - hypothetical protein IL0144 14 None None None 56460152 Common apbE Thiamine biosynthesis lipoprotein ApbE IL1044 140 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 56461036 Common - DNA-directed RNA polymerase specialized sigma subunit IL1936 174 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 56459247 Common - Outer membrane lipoprotein-sorting protein, LolA family IL0136 4 None None None 56461103 Common birA biotin--protein ligase IL2003 229 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 56459769 Nonpathogen dsrF hypothetical protein IL0660 2 COG2923 DsrF, Uncharacterized protein involved in the oxidation of intracellular sulfur Inorganic ion transport and metabolism 56460208 Common dsbE Probable disulfide isomerase IL1100 124 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 56461130 Common engA GTP-binding protein EngA IL2030 232 COG1160 COG1160, Predicted GTPases General function prediction only 56460703 Common - Monoamine oxidase family protein, membrane associated IL1599 25 COG4716 COG4716, Myosin-crossreactive antigen Function unknown 56460886 Common - Uncharacterized membrane protein, contains PAS domain IL1786 4 None None None 56459532 Common - Secreted protein IL0421 67 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 56459727 Common - hypothetical protein IL0618 23 None None None 56459330 Common metB Cystathionine gamma-synthase IL0219 210 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 56459399 Nonpathogen - hypothetical protein IL0288 1 None None None 56459311 Common - K+ uptake system component IL0200 109 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 56461541 Common acrR AcrAB operon repressor IL2441 130 COG1309 AcrR, Transcriptional regulator Transcription 56459567 Common ampE regulatory protein AmpE IL0456 22 COG3725 AmpE, Membrane protein required for beta-lactamase induction Defense mechanisms 56460285 Common - Signaling protein with a cAMP-binding, CBS domains and predicted nucleotidyltransferase domain IL1177 146 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 56459329 Common cysM Cysteine synthase B IL0218 226 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 56461428 Common - Dipeptidyl aminopeptidase IL2328 98 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 56460682 Common - Outer membrane protein IL1576 55 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 56459753 Common - Type I site-specific restriction-modification system, R subunit (helicase) IL0644 129 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 56459426 Common - Predicted NADP-dependent oxidoreductase IL0315 167 COG2130 COG2130, Putative NADP-dependent oxidoreductases General function prediction only 56460735 Common - Outer membrane efflux protein IL1634 70 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 56461366 Common - hypothetical protein IL2266 21 COG3495 COG3495, Uncharacterized protein conserved in bacteria Function unknown 56461152 Common katE Catalase-related protein IL2052 49 COG0753 KatE, Catalase Inorganic ion transport and metabolism 56461431 Common - Pirin-related protein IL2331 145 COG1741 COG1741, Pirin-related protein General function prediction only 56461409 Common fkpA FKBP-type peptidyl-prolyl cis-trans isomerase IL2309 139 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 56459173 Nonpathogen - Membrane fusion-like protein IL0062 3 None None None 56460688 Common - hypothetical protein IL1584 36 COG4728 COG4728, Uncharacterized protein conserved in bacteria Function unknown 56461188 Common - Predicted hydrolase of the alpha/beta superfamily IL2088 41 COG2819 COG2819, Predicted hydrolase of the alpha/beta superfamily General function prediction only 56461509 Common - hypothetical protein IL2409 131 COG0432 COG0432, Uncharacterized conserved protein Function unknown 56461317 Common gshB glutathione synthetase IL2217 126 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 56461096 Common - Na+-dependent transporter of the SNF family IL1996 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 56459224 Common hmuT ABC-type hemin transport system, periplasmic component IL0113 105 COG4558 ChuT, ABC-type hemin transport system, periplasmic component Inorganic ion transport and metabolism 56459840 Common pspA Phage shock protein A IL0731 101 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 56461711 Common tnsC Transposon Tn7 transposition protein tnsC IL2611 18 None None None 56460018 Common - Flp/Fap pilin homolog IL0910 5 None None None 56461228 Common - Predicted flavoprotein IL2128 75 COG0431 COG0431, Predicted flavoprotein General function prediction only 56460039 Common pth peptidyl-tRNA hydrolase IL0931 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 56461653 Common xerC Site-specific recombinase XerC IL2553 226 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 56459644 Common - Protein containing N-terminal predicted GTPase domain IL0535 6 COG3596 COG3596, Predicted GTPase General function prediction only 56460868 Common - ABC-type transport system, ATPase component IL1767 249 COG4181 COG4181, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 56459940 Common lpxB Lipid A disaccharide synthetase IL0832 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 56460139 Common lpxH UDP-2,3-diacylglucosamine hydrolase IL1031 77 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 56461691 Common - Uncharacterized conserved membrane protein, probable transporter IL2591 12 COG0701 COG0701, Predicted permeases General function prediction only 56461478 Common - Na+/H+ antiporter IL2378 75 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 56460033 Common prfA Protein chain release factor A IL0925 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 56461080 Common - Uncharacterized Fe-S oxidoreductase IL1980 205 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 56460564 Common - D-alanyl-D-alanine carboxypeptidase IL1456 23 COG1876 VanY, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 56459918 Common rnc Rnase III, dsRNA-specific ribonuclease IL0810 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 56460821 Common - Chemotaxis protein CheY IL1720 214 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 56461382 Common cutA Uncharacterized protein involved in tolerance to divalent cations IL2282 121 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 56459667 Common - Glycosyltransferase IL0558 191 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 56459506 Common - S30EA ribosomal protein IL0395 129 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 56460303 Common fliK Flagellar hook-length control protein IL1195 38 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 56459504 Common - hypothetical protein IL0393 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 56460362 Common - Transcriptional regulator, LysR family IL1254 167 COG0583 LysR, Transcriptional regulator Transcription 56460695 Common - Glyoxalase/dioxygenase superfamily protein IL1591 11 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 56459344 Common - phosphoglyceromutase IL0233 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 56460558 Common - hypothetical protein IL1450 9 None None None 56460159 Common - Short-chain alcohol dehydrogenase family enzyme IL1051 25 COG3007 COG3007, Uncharacterized paraquat-inducible protein B Function unknown 56459162 Common tra5_1 Transposase Tra5 related protein IL0050 111 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 56460140 Common ppiB Peptidyl-prolyl cis-trans isomerase (rotamase), cyclophilin family IL1032 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 56461099 Common - Carboxynorspermidine dehydrogenase IL1999 58 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 56461347 Common hrpB Helicase, ATP-dependent IL2247 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 56459588 Common obgE GTPase ObgE IL0477 236 COG0536 Obg, Predicted GTPase General function prediction only 56459749 Common - Predicted transcriptional regulator IL0640 33 COG3311 AlpA, Predicted transcriptional regulator Transcription 56461528 Common - Secreted protein related to cyanophycinase CphE IL2428 9 COG4242 CphB, Cyanophycinase and related exopeptidases Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism 56460147 Common - Predicted extracellular enzyme of alpha/beta hydrolase superfamily IL1039 13 None None None 56461647 Common recQ Superfamily II DNA helicase, RecQ IL2547 234 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 56460330 Common - Co/Zn/Cd efflux system membrane component IL1222 177 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 56459895 Common - Phosphinothricin N-acetyltransferase, putative IL0786 122 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 56460729 Common tra5_5 Transposase Tra5 related protein IL1628 146 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 56459298 Common - Radical enzyme activating protein IL0187 21 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 56459965 Common - Signaling protein with a sensor domain and GGDEF domain IL0857 179 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 56459945 Common - Bacterial surface antigen IL0837 160 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 56459880 Common - hypothetical protein IL0771 3 None None None 56459982 Common - Acyl-CoA dehydrogenase IL0874 171 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 56461283 Nonpathogen - Secreted protein, containing von Willebrand factor (vWF) type A domain IL2183 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 56459228 Common - Outer membrane protein IL0117 29 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 56461512 Common - hypothetical protein IL2412 4 None None None 56461557 Common hslU ATP-dependent protease ATP-binding subunit IL2457 210 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 56460305 Common fliI flagellum-specific ATP synthase IL1197 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 56461603 Common - Uncharacterized metal-binding protein IL2503 24 COG5266 CbiK, ABC-type Co2+ transport system, periplasmic component Inorganic ion transport and metabolism 56459131 Common smf Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake IL0019 210 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 56461112 Common xseA exodeoxyribonuclease VII large subunit IL2012 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 56460745 Common merT Mercuric ion transport protein, MerT IL1644 21 None None None 56459987 Common - acetyl-CoA synthetase IL0879 209 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 56459901 Nonpathogen - hypothetical protein IL0793 1 None None None 56461039 Common priB primosomal replication protein N IL1939 26 COG2965 PriB, Primosomal replication protein N DNA replication, recombination, and repair 56461144 Common - hypothetical protein IL2044 2 None None None 56459235 Nonpathogen - Phosphopantetheinyl transferase related enzyme IL0124 1 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 56460879 Common - 3-methyladenine DNA glycosylase homolog IL1779 52 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 56459326 Common comM Competence related ATPase with chaperone activity IL0215 205 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 56459188 Nonpathogen - hypothetical protein IL0077 2 None None None 56461054 Common parE DNA topoisomerase IV subunit B IL1954 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 56460406 Common ccoO Cbb3-type cytochrome oxidase, cytochrome c subunit IL1298 82 COG2993 CcoO, Cbb3-type cytochrome oxidase, cytochrome c subunit Energy production and conversion 56461221 Common rdgC recombination associated protein IL2121 53 COG2974 RdgC, DNA recombination-dependent growth factor C DNA replication, recombination, and repair 56461186 Nonpathogen - hypothetical protein IL2086 1 None None None 56460898 Common rnfG Predicted NADH:ubiquinone oxidoreductase, subunit RnfG IL1798 54 COG4659 RnfG, Predicted NADH:ubiquinone oxidoreductase, subunit RnfG Energy production and conversion 56461262 Common glpQ glycerophosphodiester phosphodiesterase IL2162 105 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 56459381 Common kbl 2-amino-3-ketobutyrate coenzyme A ligase IL0270 192 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 56460227 Common flhF flagellar biosynthesis regulator FlhF IL1119 247 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 56460046 Common - Short chain dehydrogenase family protein IL0938 235 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 56461397 Common - 4-Hydroxybutyrate CoA-transferase (N-terminal) fused to acetyltransferase (C-terminal) domain of GNAT superfamily IL2297 143 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 56461564 Common - Il-IS_1, transposase IL2463.1 105 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 56460659 Common - hypothetical protein IL1553 119 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 56459367 Common - Cytochrome oxidase complex biogenesis factor, membrane protein IL0256 37 COG3346 COG3346, Uncharacterized conserved protein Function unknown 56459704 Nonpathogen - Predicted membrane protein IL0595 2 None None None 56460177 Common - Glutamine amidotransferase related enzyme IL1069 114 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 56461338 Common anmK anhydro-N-acetylmuramic acid kinase IL2238 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 56461045 Common - hypothetical protein IL1945 27 COG1714 COG1714, Predicted membrane protein/domain Function unknown 56461587 Common - Intracellular signaling protein (PAS,GAF,GGDEF domains) IL2487 182 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 56460570 Common perM Permease PerM IL1462 185 COG0628 PerM, Predicted permease General function prediction only 56460455 Common - Predicted phosphatase related to gph IL1347 192 COG0546 Gph, Predicted phosphatases General function prediction only 56459911 Common mazG Predicted pyrophosphatase MazG IL0803 157 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 56459158 Common gst Glutathione S-transferase IL0046 101 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 56461394 Common - hypothetical protein IL2294 23 COG3085 COG3085, Uncharacterized protein conserved in bacteria Function unknown 56459164 Common - Predicted permease IL0052 72 COG2962 RarD, Predicted permeases General function prediction only 56461349 Common sfsA SfsA IL2249 105 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 56460828 Common ffh Signal recognition particle GTPase IL1727 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 56460498 Common - hypothetical protein IL1390 38 COG2802 COG2802, Uncharacterized protein, similar to the N-terminal domain of Lon protease General function prediction only 56461622 Common - hypothetical protein IL2522 13 None None None 56459765 Common - TesB-like acyl-CoA thioesterase IL0656 16 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 56461274 Common - hypothetical protein IL2174 23 COG4539 COG4539, Predicted membrane protein Function unknown 56461514 Common - Intracellular signaling protein (PAS,GGDEF domains) IL2414 183 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 56460254 Common flgC Flagellar basal body rod protein IL1146 123 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 56460834 Nonpathogen - Predicted membrane protein IL1733 1 None None None 56460267 Common - hypothetical protein IL1159 29 COG4134 COG4134, ABC-type uncharacterized transport system, periplasmic component General function prediction only 56460727 Common - Transposon related ORF, HTH transcriptional regulator IL1626 77 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 56460473 Common - Iron-sulfur cluster-binding protein IL1365 51 COG0633 Fdx, Ferredoxin Energy production and conversion 56459534 Common - Predicted endonuclease IL0423 116 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 56461655 Common dapF diaminopimelate epimerase IL2555 203 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 56460967 Common ampG MFS family muropeptide transporter IL1867 102 None None None 56461447 Common hemH Protoheme ferro-lyase IL2347 162 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 56461279 Common - Kynureninase IL2179 122 COG3844 COG3844, Kynureninase Amino acid transport and metabolism 56460313 Common - hypothetical protein IL1205 45 COG3816 COG3816, Uncharacterized protein conserved in bacteria Function unknown 56459447 Common hflC Membrane protease, stomatin/prohibitin family IL0336 203 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 56460222 Common cheA Chemotaxis-specific histidine kinase IL1114 152 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 56461133 Common hisS Histidyl-tRNA synthetase IL2033 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 56460441 Common - Mg-dependent Dnase homolog IL1333 236 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 56461030 Common pepN_2 Zn-dependent aminopeptidase IL1930 54 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 56461123 Common pulG Type II secretory pathway, pseudopilin PulG IL2023 102 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 56460960 Nonpathogen priC Primosomal replication protein C IL1860 1 COG3923 PriC, Primosomal replication protein N'' DNA replication, recombination, and repair 56461739 Common rnpA RNase P protein component IL2639 73 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 56460311 Common - Signal transduction histidine kinase (contains PAS domain) IL1203 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 56460877 Common - Coenzyme A transferase IL1777 101 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 56461490 Common - Xaa-Pro dipeptidase family enzyme IL2390 89 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 56460295 Common flhB flagellar biosynthesis protein FlhB IL1187 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 56459514 Common - ABC-type transport system involved in resistance to organic solvents, ATPase component IL0403 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 56460849 Common - NADH:flavin oxidoreductase, Old Yellow Enzyme family IL1748 204 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 56459404 Common - Enzyme related to eukaryotic diacylglycerol kinase IL0293 120 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 56459151 Common - Acylaminoacyl-peptidase IL0039 136 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 56460457 Common rne RNase E IL1349 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 56460650 Common - Signaling protein with a PAS and GGDEF domains IL1544 183 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 56459821 Common - hypothetical protein IL0712 4 None None None 56459494 Common mreD Rod shape-determining protein IL0383 62 COG2891 MreD, Cell shape-determining protein Cell envelope biogenesis, outer membrane 56461373 Common trmA tRNA (uracil-5-)-methyltransferase IL2273 185 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 56459773 Common crcB Integral membrane protein IL0664 188 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 56459208 Nonpathogen - Cytochrome B561 IL0097 2 COG3038 CybB, Cytochrome B561 Energy production and conversion 56459860 Common ispF 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IL0751 189 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 56460356 Nonpathogen - hypothetical protein IL1248 1 None None None 56459905 Nonpathogen - hypothetical protein IL0797 1 None None None 56461682 Common - Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains IL2582 175 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 56460756 Common - isoprenoid biosynthesis protein with amidotransferase-like domain IL1655 38 COG3155 ElbB, Uncharacterized protein involved in an early stage of isoprenoid biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 56459759 Common - Acetyltransferase, GNAT family IL0650 6 None None None 56459916 Common recO Recombinational DNA repair protein RecO, RecF pathway IL0808 70 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 56461521 Common - hypothetical protein IL2421 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 56460862 Common - Predicted amino acid aldolase or racemase IL1761 53 COG3616 COG3616, Predicted amino acid aldolase or racemase Amino acid transport and metabolism 56459479 Common mshM General secretion pathway protein, ATPase IL0368 73 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 56460246 Common flgK Flagellar hook-associated protein IL1138 123 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 56460118 Common topA DNA topoisomerase I IL1010 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 56460767 Common abgT_1 Probable p-aminobenzoyl-glutamate transporter IL1666 43 COG2978 AbgT, Putative p-aminobenzoyl-glutamate transporter Coenzyme metabolism 56459752 Common hsdS Restriction endonuclease S subunit IL0643 98 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 56461468 Common tatC Sec-independent protein secretion pathway component TatC IL2368 203 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 56460260 Common flgN Flagellar synthesis protein FlgN IL1152 7 None None None 56461052 Common plsC 1-acyl-sn-glycerol-3-phosphate acyltransferase IL1952 138 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 56461315 Common metK S-adenosylmethionine synthetase IL2215 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 56460701 Common - Cytochrome B561 IL1597 58 COG3038 CybB, Cytochrome B561 Energy production and conversion 56459885 Nonpathogen - Predicted membrane protein IL0776 1 None None None 56459742 Common - Lipoprotein signal peptidase IL0633 197 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 56459828 Common - Glutathione S-transferase related protein IL0719 105 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 56460965 Common - Uncharacterized conserved lipoprotein IL1865 3 COG3056 COG3056, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 56460185 Common nadA quinolinate synthetase IL1077 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 56460204 Common hnr Response regulator of sigma subunit, serine phosphatase (CheY-RsbU) IL1096 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 56461735 Common - hypothetical protein IL2635 52 COG1289 COG1289, Predicted membrane protein Function unknown 56461351 Common - Glutamyl-tRNA synthetase related protein IL2251 242 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 56460817 Common - Predicted amidohydrolase IL1716 37 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 56459856 Common - hypothetical protein IL0747 69 COG1238 COG1238, Predicted membrane protein Function unknown 56461387 Common prmA ribosomal protein L11 methyltransferase IL2287 177 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 56459772 Common serS seryl-tRNA synthetase IL0663 245 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 56459717 Common aceA isocitrate lyase IL0608 128 COG2224 AceA, Isocitrate lyase Energy production and conversion 56460937 Common hisB imidazole glycerol-phosphate dehydratase/histidinol phosphatase IL1837 219 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 56460714 Common - Acyl carrier protein phosphodiesterase IL1610 92 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 56459555 Common - Membrane protein IL0444 189 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 56460491 Common - Cyclopropane-fatty-acyl-phospholipid synthase IL1383 126 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 56459267 Common csgG CsgG IL0156 17 COG1462 CsgG, Uncharacterized protein involved in formation of curli polymers Cell envelope biogenesis, outer membrane 56459730 Common aefA Small-conductance mechanosensitive channel IL0621 207 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 56459980 Common - Acetyl-CoA acetyltransferase IL0872 184 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 56461450 Common - Predicted permease IL2350 16 COG0730 COG0730, Predicted permeases General function prediction only 56459979 Common madN Malonate decarboxylase Na+ pump IL0871 35 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 56461725 Common atpB F0F1 ATP synthase subunit A IL2625 206 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 56460586 Common glnS glutaminyl-tRNA synthetase IL1478 245 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 56459242 Common - 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase related enzyme IL0131 22 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 56460956 Common - Biopolymer transport protein IL1856 137 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 56460761 Common kdpE Response regulator (CheY, wHTH domains) IL1660 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 56459635 Common - hypothetical protein IL0525 40 COG3002 COG3002, Uncharacterized protein conserved in bacteria Function unknown 56460131 Common - hypothetical protein IL1023 17 None None None 56459291 Common - Ferredoxin IL0180 114 COG2768 COG2768, Uncharacterized Fe-S center protein General function prediction only 56460450 Common fabH 3-oxoacyl-[acyl-carrier-protein] synthase III IL1342 224 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 56461208 Common pstC ABC-type phosphate transport system, permease component IL2108 220 COG4590 COG4590, ABC-type uncharacterized transport system, permease component General function prediction only 56460054 Nonpathogen - Predicted membrane protein IL0946 1 None None None 56460461 Nonpathogen - hypothetical protein IL1353 1 COG3771 COG3771, Predicted membrane protein Function unknown 56461473 Common ubiE 2-polyprenylmethoxybenozoquinol methylase IL2373 224 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 56461389 Common fis Factor for inversion stimulation Fis, transcriptional activator IL2289 72 COG2901 Fis, Factor for inversion stimulation Fis, transcriptional activator Transcription / DNA replication, recombination, and repair 56460840 Common oraA OraA IL1739 87 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 56461257 Common - homoserine O-acetyltransferase IL2157 131 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 56459281 Common - hypothetical protein IL0170 39 None None None 56460691 Nonpathogen - Predicted metal-binding protein IL1587 1 None None None 56461554 Common - Arginase family protein IL2454 25 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 56460983 Common deoC Deoxyribose-phosphate aldolase IL1883 128 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 56460810 Common cysB transcriptional regulator CysB IL1709 190 COG0583 LysR, Transcriptional regulator Transcription 56461009 Common mnhD putative monovalent cation/H+ antiporter subunit D IL1909 209 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 56461419 Common - Predicted glycosyltransferase IL2319 8 None None None 56459470 Common - hypothetical protein IL0359 11 COG1289 COG1289, Predicted membrane protein Function unknown 56460332 Common - Outer membrane efflux protein IL1224 46 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 56460198 Common - Signaling protein with a periplasmic binding domain and GGDEF domain IL1090 185 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 56461023 Common rplD 50S ribosomal protein L4 IL1923 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 56460070 Common - Predicted extracellular metal-dependent peptidase IL0962 2 None None None 56460548 Common - Zn-dependent alcohol dehydrogenase IL1440 194 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 56461320 Nonpathogen - hypothetical protein IL2220 1 None None None 56459322 Common - Protein-disulfide isomerase IL0211 68 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 56461177 Common nfnB Nitroreductase IL2077 71 COG0778 NfnB, Nitroreductase Energy production and conversion 56461298 Common - Signal transduction histidine kinase IL2198 41 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 56459203 Common - Heme oxygenase related enzyme IL0092 25 COG5424 COG5424, Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C Coenzyme metabolism 56460521 Common dbpA ATP-dependent RNA helicase DbpA IL1413 236 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 56461729 Common gidB glucose-inhibited division protein B IL2629 183 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 56459723 Common argF Ornithine carbamoyltransferase IL0614 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 56461438 Common gdhA glutamate dehydrogenase IL2338 167 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 56460168 Common fbpB ABC-type Fe3+ transport system, permease component IL1060 175 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 56460416 Common - hypothetical protein IL1308 13 COG5473 COG5473, Predicted integral membrane protein Function unknown 56460063 Common mltB Membrane-bound lytic murein transglycosylase B IL0955 102 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 56459831 Common - 4-hydroxyphenylpyruvate dioxygenase IL0722 77 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 56459585 Common ispA_1 Geranylgeranyl pyrophosphate synthase IL0474 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 56460733 Common - Metal efflux system membrane component (silver efflux pump related) IL1632 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 56461488 Common betT Choline-glycine betaine transporter IL2388 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 56460439 Common - Na+-dependent transporter of the SNF family IL1331 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 56459929 Common slyD FKBP-type peptidyl-prolyl cis-trans isomerase IL0821 136 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 56459962 Common syd SecY interacting protein Syd IL0854 20 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 56459403 Common - hypothetical protein IL0292 2 None None None 56459694 Common - Cytosine/adenosine deaminase putative IL0585 220 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 56461248 Common secD preprotein translocase subunit SecD IL2148 209 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 56460569 Common bcp thioredoxin-dependent thiol peroxidase IL1461 206 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 56459450 Common secE preprotein translocase subunit SecE IL0339 46 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 56461336 Common tyrS tyrosyl-tRNA synthetase IL2236 242 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 56460378 Common - hypothetical protein IL1270 28 COG3139 COG3139, Uncharacterized protein conserved in bacteria Function unknown 56460422 Common - Leucine dehydrogenase IL1314 167 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 56460346 Nonpathogen - Uncharacterized conserved protein, IL-2 family IL1238 1 None None None 56461206 Common pstB ABC-type phosphate transport system, ATPase component IL2106 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 56460512 Nonpathogen - Predicted membrane protein IL1404 1 None None None 56460673 Common - Uncharacterized conserved membrane protein, LemA family IL1567 127 COG1704 LemA, Uncharacterized conserved protein Function unknown 56461085 Common proB gamma-glutamyl kinase IL1985 192 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 56459271 Common csgB Minor curlin subunit CsgB, nucleation component of curlin monomers IL0160 17 None None None 56460083 Common hflB Membrane ATP-dependent Zn protease IL0975 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 56460852 Common trpE anthranilate synthase component I IL1751 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 56459480 Common mshN Membrane associated TPR repeats containing protein IL0369 31 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 56459922 Common rseB Negative regulator of sigma E activity IL0814 47 COG3026 RseB, Negative regulator of sigma E activity Signal transduction mechanisms 56461629 Nonpathogen - Type II site-specific deoxyribonuclease IL2529 2 None None None 56459487 Common mshD Pilin protein IL0376 7 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 56460538 Common - Dipeptide/tripeptide permease IL1430 81 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 56459461 Common tufB_2 elongation factor Tu IL0350 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 56459452 Common rplK 50S ribosomal protein L11 IL0341 248 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 56461637 Common - hypothetical protein IL2537 44 COG4805 COG4805, Uncharacterized protein conserved in bacteria Function unknown 56461641 Common - ABC-type multidrug transport system, ATPase and permease components IL2541 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 56460280 Common - Secreted dipeptidyl aminopeptidase IL1172 121 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 56460170 Common - Mg/Co transporter IL1062 111 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 56460385 Common pepN_1 Aminopeptidase N IL1277 160 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 56459439 Common - C-terminal predicted sugar kinase fused to N-terminal uncharaterized domain IL0328 222 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 56460466 Common - histidinol-phosphate aminotransferase IL1358 235 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 56461667 Common - Homolog of DinP DNA polymerase involved in DNA repair IL2567 70 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 56460323 Nonpathogen - hypothetical protein IL1215 4 None None None 56461495 Common - Amino acid transporter IL2395 82 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 56460509 Common - Zn-ribbon protein IL1401 6 None None None 56460980 Common - Methyl-accepting chemotaxis protein (contains HAMP domain) IL1880 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 56459463 Common - Glutaminase IL0352 72 COG2066 GlsA, Glutaminase Amino acid transport and metabolism 56460606 Common sucD Succinyl-CoA synthetase, alpha subunit IL1500 214 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 56461306 Common queA S-adenosylmethionine:tRNA-ribosyltransferase-isomerase IL2206 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 56459178 Common - hypothetical protein IL0067 85 COG1238 COG1238, Predicted membrane protein Function unknown 56459616 Common - Predicted permease IL0505 91 COG0730 COG0730, Predicted permeases General function prediction only 56460612 Common sdhD Succinate dehydrogenase, hydrophobic anchor subunit IL1506 52 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 56461578 Common - Peroxiredoxin, AhpC/Tsa family IL2478 82 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 56459122 Common fadA 3-ketoacyl-CoA thiolase IL0010 187 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 56460793 Common - hypothetical protein IL1692 12 None None None 56459943 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase IL0835 164 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 56460287 Common - hypothetical protein IL1179 50 COG4327 COG4327, Predicted membrane protein Function unknown 56461697 Common - Predicted polysaccharide hydrolase related to endo alpha-1,4 polygalactosaminidase IL2597 19 COG3868 COG3868, Uncharacterized conserved protein Function unknown 56461703 Nonpathogen - Predicted secreted protein IL2603 1 None None None 56460519 Common - Outer membrane protein, porin family IL1411 13 None None None 56460922 Common dsbB Disulfide bond formation protein IL1822 49 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 56460279 Nonpathogen - Predicted secreted protein IL1171 1 None None None 56459957 Common - Predicted pseudouridylate synthase, Rlu family IL0849 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 56459985 Common - 3-methylcrotonyl-CoA carboxylase alpha chain IL0877 237 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 56461368 Common - Uncharacterized conserved membrane or secreted protein IL2268 17 None None None 56460328 Nonpathogen - hypothetical protein IL1220 5 None None None 56460712 Common - Short chain dehydrogenase/reductase family protein IL1608 233 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 56460972 Common glyA Glycine/serine hydroxymethyltransferase IL1872 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 56460786 Common kefC Kef-type K+ transport system, membrane component IL1685 205 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 56461456 Common pnuC Nicotinamide mononucleotide transporter IL2356 51 COG3201 PnuC, Nicotinamide mononucleotide transporter Coenzyme metabolism 56461090 Common blc Outer membrane lipoprotein IL1990 69 COG3040 Blc, Bacterial lipocalin Cell envelope biogenesis, outer membrane 56461610 Common - Predicted serine endoprotease IL2510 21 None None None 56461433 Nonpathogen - hypothetical protein IL2333 1 None None None 56459313 Common - Methyl-accepting chemotaxis protein (HAMP, Cache domains) IL0202 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 56461543 Common - Predicted flavoprotein IL2443 105 COG0431 COG0431, Predicted flavoprotein General function prediction only 56461150 Common - hypothetical protein IL2050 25 None None None 56460671 Common ompA Outer membrane protein and related peptidoglycan-associated (lipo)proteins IL1565 175 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 56460085 Common - Predicted RNA-binding protein containing KH domain IL0977 94 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 56461195 Common - Transcriptional regulator, LysR family IL2095 187 COG0583 LysR, Transcriptional regulator Transcription 56461562 Common rpmE Ribosomal protein L31 IL2462 206 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 56459575 Common - Probable Co/Zn/Cd efflux system membrane component IL0464 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 56461157 Common - Membrane-fusion protein homolog IL2057 119 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 56459354 Common - Prolyl 4-hydroxylase alpha subunit homolog, 2OG-Fe(II) oxygenase family IL0243 31 COG3751 EGL-9, Predicted proline hydroxylase Posttranslational modification, protein turnover, chaperones 56459974 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase IL0866 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 56459648 Common - Chain length determinant protein IL0539 9 COG3765 WzzB, Chain length determinant protein Cell envelope biogenesis, outer membrane 56459240 Common - hypothetical protein IL0129 28 COG4648 COG4648, Predicted membrane protein Function unknown 56459608 Common rimK Ribosomal protein S6 modification enzyme IL0497 151 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 56461353 Common folK_3 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase IL2253 198 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 56459569 Common aceE pyruvate dehydrogenase subunit E1 IL0458 153 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 56459113 Common dnaA ATPase involved in DNA replication initiation IL0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 56461197 Common ubiH 2-polyprenyl-6-methoxyphenol hydroxylase IL2097 124 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 56459306 Common - hypothetical protein IL0195 76 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 56459560 Common coaE Dephospho-CoA kinase IL0449 208 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 56459210 Common - Uncharacterized conserved domain often associated with AraC-type DNA-binding domain IL0099 2 None None None 56460778 Common - hypothetical protein IL1677 22 COG3021 COG3021, Uncharacterized protein conserved in bacteria Function unknown 56460636 Common folK_1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase IL1530 13 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 56461501 Common capC Capsular polyglutamate biosynthesis membrane protein CapC IL2401 5 None None None 56459641 Nonpathogen - hypothetical protein IL0532 1 None None None 56460478 Common sbcB exonuclease I IL1370 51 COG2925 SbcB, Exonuclease I DNA replication, recombination, and repair 56460979 Common prfC peptide chain release factor 3 IL1879 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 56460918 Common - Beta-lactamase class C family protein IL1818 130 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 56460411 Nonpathogen - hypothetical protein IL1303 1 COG3197 FixS, Uncharacterized protein, possibly involved in nitrogen fixation Inorganic ion transport and metabolism 56460502 Common pheT phenylalanyl-tRNA synthetase subunit beta IL1394 245 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 56459430 Common - Membrane protein related to Kef-type K+ transport system NAD-binding component IL0319 23 None None None 56461243 Nonpathogen - hypothetical protein IL2143 6 None None None 56460192 Common - Predicted thioesterase IL1084 134 COG0824 FcbC, Predicted thioesterase General function prediction only 56459324 Common - Thiol:disulfide interchange protein IL0213 135 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 56461027 Nonpathogen - Predicted secreted protein IL1927 1 None None None 56460799 Common dniR Soluble lytic murein transglycosylase IL1698 135 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 56459669 Common - hypothetical protein IL0560 8 None None None 56460024 Common - Carboxyl-terminal protease IL0916 108 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 56459674 Common - Polysaccharide biosynthesis/export protein IL0565 109 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 56461675 Common ahpD Probable alkyl hydroperoxide reductase D, carboxymuconolactone decarboxylase family enzyme IL2575 27 COG2128 COG2128, Uncharacterized conserved protein Function unknown 56459459 Common rpsG 30S ribosomal protein S7 IL0348 241 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 56460128 Common pdxB Erythronate-4-phosphate dehyrogenase IL1020 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 56459868 Common - putative hydroxylase IL0759 45 COG3128 PiuC, Uncharacterized iron-regulated protein Function unknown 56459908 Nonpathogen - hypothetical protein IL0800 1 None None None 56461329 Common imp Organic solvent tolerance protein OstA IL2229 124 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 56459967 Common - SmpA /OmlA family lipoprotein IL0859 5 None None None 56460747 Common merA_2 Mercuric ion reductase IL1646 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 56460657 Nonpathogen - Protein containing predicted Zn-ribbon like domain IL1551 1 None None None 56460179 Common - Probable aminopeptidase fused to fibronectin type 3 domain IL1071 23 COG2234 Iap, Predicted aminopeptidases General function prediction only 56460142 Common - Leucyl aminopeptidase IL1034 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 56459932 Common recJ RecJ IL0824 195 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 56459683 Common - Il-IS_1, transposase IL0573.1 105 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 56459994 Common proS prolyl-tRNA synthetase IL0886 249 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 56459660 Common - Sialic acid synthase IL0551 78 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 56461539 Common - hemolysin III-like protein IL2439 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 56460754 Common - RelE/ParE family protein, cytotoxic translational repressor of toxin-antitoxin stability system IL1653 10 None None None 56459696 Common - Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein IL0587 146 COG4623 COG4623, Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein Cell envelope biogenesis, outer membrane 56460044 Common - Protein containing plastocyanin/azurin family domain IL0936 19 None None None 56460764 Common - Il-IS_1, transposase IL1662.1 105 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 56459365 Common ctaA Uncharacterized protein required for cytochrome oxidase assembly IL0254 52 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 56459237 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase IL0126 67 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 56460620 Common comEC DNA uptake-related membrane-associated competence protein IL1514 166 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 56461340 Common - HesB/IscA family protein IL2240 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 56460239 Common rpsT Ribosomal protein S20 IL1131 203 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 56461532 Common pldB Lysophospholipase IL2432 81 COG2267 PldB, Lysophospholipase Lipid metabolism 56461617 Common vapC Predicted PIN-like nuclease IL2517 70 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 56460660 Common - hypothetical protein IL1554 3 None None None 56460005 Common - Oligoketide cyclase/lipid transport protein, putative IL0897 103 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 56460905 Common sodB Superoxide dismutase, Fe dependent IL1805 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 56460408 Common ccoP Cytochrome c oxidase, cbb3-type, subunit III IL1300 92 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 56460649 Common - hypothetical protein IL1543 6 None None None 56461605 Common - Na+/anion symporter IL2505 152 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 56461581 Common - Transcriptional regulator, Lpr family IL2481 151 COG1522 Lrp, Transcriptional regulators Transcription 56459601 Common - HPt domain IL0490 18 COG2198 ArcB, FOG: HPt domain Signal transduction mechanisms 56460368 Common - Signal transduction ATPase, FimS family IL1260 103 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 56459544 Common mraY UDP-N-acetylmuramyl pentapeptide phosphotransferase IL0433 223 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 56460684 Common - Uncharacterized iron-regulated membrane protein IL1578 41 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 56460225 Common fliA flagellar biosynthesis sigma factor IL1117 215 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 56459798 Common - Glutaredoxin family protein IL0689 25 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 56461399 Common - Probable Na+/H+-dicarboxylate symporter IL2299 122 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 56459897 Common - hypothetical protein IL0789 13 None None None 56461184 Common - Predicted transcriptional regulator, HTH-type IL2084 11 COG1396 HipB, Predicted transcriptional regulators Transcription 56461281 Common - Multidomain protein containing OsmC-like N-terminal domain and uncharacterized conserved domain IL2181 57 COG1944 COG1944, Uncharacterized conserved protein Function unknown 56461370 Nonpathogen - hypothetical protein IL2270 1 None None None 56460212 Common ccmC ABC-type transport system involved in cytochrome c biogenesis, permease component IL1104 107 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 56461526 Common pyrE orotate phosphoribosyltransferase IL2426 151 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 56460627 Common - hypothetical protein IL1521 7 None None None 56460871 Common gltX glutamyl-tRNA synthetase IL1770 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 56461260 Common - RimK-like domain (C-terminal) fused to uncharacterized conserved domain IL2160 70 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 56461226 Common - glyceraldehyde-3-phosphate dehydrogenase IL2126 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 56459623 Common - Dinucleotide-utilizing enzyme of HesA/MoeB/ThiF family IL0512 223 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 56460030 Common - hypothetical protein IL0922 29 COG3094 COG3094, Uncharacterized protein conserved in bacteria Function unknown 56459171 Common - Membrane associated protein containing LuxR-like DNA-binding HTH domain IL0060 9 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 56460097 Common recN ATPase involved in DNA repair, RecN IL0989 209 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 56459391 Common - hypothetical protein IL0280 19 None None None 56460891 Common - Aspartate aminotransferase IL1791 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 56460859 Common - hypothetical protein IL1758 62 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 56459952 Common tsf elongation factor Ts IL0844 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 56459642 Common - Uncharacterized protein containing Fic domain IL0533 14 COG3177 COG3177, Uncharacterized conserved protein Function unknown 56461268 Common - Membrane associated signaling protein (contains EAL and inactivated GGDEF domain) IL2168 158 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 56460037 Common prsA ribose-phosphate pyrophosphokinase IL0929 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 56460589 Common - hypothetical protein IL1481 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 56460832 Common gshA Gamma-glutamylcysteine synthetase IL1731 58 COG2918 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 56461689 Common - hypothetical protein IL2589 26 COG3503 COG3503, Predicted membrane protein Function unknown 56459783 Common clpA ATP-binding subunit of Clp protease and DnaK/DnaJ chaperones IL0674 223 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 56459739 Common - Xaa-Pro aminopeptidase IL0630 241 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 56460487 Nonpathogen - hypothetical protein IL1379 1 None None None 56461082 Common oprF OprF IL1982 160 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 56461476 Common - Intracellular signaling protein (EAL,mHD,GYP domains) IL2376 52 COG3434 COG3434, Predicted signal transduction protein containing EAL and modified HD-GYP domains Signal transduction mechanisms 56460722 Common - hypothetical protein IL1619 31 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 56459275 Common - hypothetical protein IL0164 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 56460850 Nonpathogen - hypothetical protein IL1749 1 None None None 56459508 Common yhbG Unclassified ABC-type transport system, ATPase component IL0397 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 56460203 Common - hypothetical protein IL1095 2 None None None 56459586 Common rplU 50S ribosomal protein L21 IL0475 215 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 56459873 Common - Uncharacterized secreted protein of SCO1/SenC/PrrC family IL0764 61 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 56460301 Common fliM flagellar motor switch protein FliM IL1193 113 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 56459890 Nonpathogen - hypothetical protein IL0781 2 None None None 56460551 Common - hypothetical protein IL1443 43 COG4805 COG4805, Uncharacterized protein conserved in bacteria Function unknown 56460708 Common - Alpha/beta superfamily hydrolase IL1604 133 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 56459257 Common - Membrane protease, stomatin/prohibitin family IL0146 189 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 56461017 Common rplP 50S ribosomal protein L16 IL1917 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 56459939 Common - Predicted glutathione S-transferase IL0831 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 56459342 Common - hypothetical protein IL0231 66 COG2861 COG2861, Uncharacterized protein conserved in bacteria Function unknown 56460693 Common - hypothetical protein IL1589 3 None None None 56459284 Common - Predicted exporter, RND superfamily IL0173 87 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 56460372 Common - methionine sulfoxide reductase B IL1264 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 56460665 Nonpathogen - Predicted membrane protein IL1559 1 None None None 56460414 Common - ATPase of the PP-loop superfamily IL1306 144 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 56461442 Common - Peroxiredoxin, AhpC/Tsa family IL2342 212 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 56459925 Common nadB L-aspartate oxidase IL0817 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 56461210 Common phoR Phosphate regulon sensor histidine kinase (contains PAS domain) IL2110 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 56459833 Common phhB pterin-4-alpha-carbinolamine dehydratase IL0724 110 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 56461727 Common parB Chromosome partitioning protein ParB IL2627 184 COG1475 Spo0J, Predicted transcriptional regulators Transcription 56460072 Common pnp polynucleotide phosphorylase/polyadenylase IL0964 239 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 56459954 Common map Methionine aminopeptidase IL0846 249 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 56460677 Common - hypothetical protein IL1571 3 None None None 56459750 Nonpathogen - hypothetical protein IL0641 1 None None None 56460994 Common rpsM 30S ribosomal protein S13 IL1894 239 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 56461482 Common gmk Guanylate kinase IL2382 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 56459499 Common tldD Predicted Zn-dependent protease IL0388 170 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 56459157 Common - Beta-lactamase class C family protein IL0045 146 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 56459626 Common - Electron transfer flavoprotein, alpha subunit IL0515 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 56460864 Common - hypothetical protein IL1763 3 None None None 56461325 Common - hypothetical protein IL2225 6 None None None 56459937 Common - Response regulator with TPR repeat IL0829 72 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 56460672 Common sIR2 NAD-dependent deacetylase IL1566 151 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 56461722 Common atpH F0F1-type ATP synthase, delta subunit IL2622 178 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 56459878 Common thiG thiazole synthase IL0769 167 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 56460271 Common - Outer membrane protein IL1163 50 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 56461204 Common serA D-3-phosphoglycerate dehydrogenase IL2104 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 56461333 Common apaG ApaG IL2233 89 COG2967 ApaG, Uncharacterized protein affecting Mg2+/Co2+ transport Inorganic ion transport and metabolism 56461064 Common exeB General secretion pathway protein B IL1964 10 None None None 56461465 Common hemB delta-aminolevulinic acid dehydratase IL2365 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 56460123 Common folC Folylpolyglutamate synthase IL1015 217 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 56461487 Common - Intracellular signaling protein (2 PAS, GGDEF domains) IL2387 127 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 56460202 Common galU UDP-glucose pyrophosphorylase IL1094 226 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 56460528 Common - DNA polymerase III subunit epsilon IL1420 65 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 56459871 Common - Copper-containing nitrite reductase IL0762 83 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 56460975 Common - hypothetical protein IL1875 7 None None None 56460904 Common - Glutaredoxin-related protein IL1804 126 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 56460777 Common - Predicted permease, DMT superfamily IL1676 59 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 56460870 Common - Carbonic anhydrase IL1769 148 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 56460644 Common - 2OG-Fe(II) oxygenase family enzyme IL1538 9 None None None 56461213 Common - Outer membrane protein (porin) IL2113 37 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 56459278 Common - Signal transduction histidine kinase IL0167 110 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 56460479 Common betA Choline dehydrogenase and related flavoproteins IL1371 88 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 56459949 Common uppS Undecaprenyl pyrophosphate synthase IL0841 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 56460052 Common - Mg/Co transporter IL0944 218 COG4535 CorC, Putative Mg2+ and Co2+ transporter CorC Inorganic ion transport and metabolism 56461378 Common - hypothetical protein IL2278 5 None None None 56459201 Common - Thermostable hemolysin related protein IL0090 12 None None None 56459992 Nonpathogen - Secreted protein containing internal repeats IL0884 2 None None None 56461723 Common atpF F0F1-type ATP synthase, subunit b IL2623 73 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 56461007 Common - putative monovalent cation/H+ antiporter subunit A IL1907 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 56460885 Common - Il-IS_1, transposase IL1784.1 105 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 56461390 Common purH IMP cyclohydrolase IL2290 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 56459633 Common nhaR Possible transcriptional activator of LysR family IL0523 181 COG0583 LysR, Transcriptional regulator Transcription 56461586 Common - Carboxymuconolactone decarboxylase family enzyme IL2486 77 COG2128 COG2128, Uncharacterized conserved protein Function unknown 56461407 Common - NUDIX family pyrophosphohydrolase containing a Zn-finger IL2307 108 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 56460169 Common fbpC ABC-type Fe3+ transport system, ATPase component IL1061 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 56459691 Common - Oar-like outer membrane protein protein, OmpA family IL0582 38 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 56461354 Common panB Ketopantoate hydroxymethyltransferase IL2254 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 56460149 Nonpathogen - BNR repeats containing secreted protein IL1041 12 COG4447 COG4447, Uncharacterized protein related to plant photosystem II stability/assembly factor General function prediction only 56461175 Common uup ATPase component of ABC transporters with duplicated ATPase domains IL2075 242 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 56460084 Common rrmJ 23S rRNA methyltransferase J IL0976 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 56460464 Common cmk Cytidylate kinase IL1356 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 56459472 Common tdk thymidine kinase IL0361 101 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 56461046 Common - Predicted permease IL1946 133 COG0795 COG0795, Predicted permeases General function prediction only 56459721 Common argC N-acetyl-gamma-glutamyl-phosphate reductase IL0612 214 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 56461168 Common - Acetyltransferase, GNAT family IL2068 116 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 56460121 Common cvpA Uncharacterized membrane protein IL1013 90 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 56461131 Common - outer membrane protein assembly complex subunit YfgL IL2031 115 COG1520 COG1520, FOG: WD40-like repeat Function unknown 56461668 Common - SulA-like SOS-response cell division inhibitor IL2568 19 COG5404 SulA, SOS-response cell division inhibitor, blocks FtsZ ring formation Cell division and chromosome partitioning 56460958 Common - TonB system biopolymer transport component IL1858 58 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 56459412 Common - hypothetical protein IL0301 28 COG4737 COG4737, Uncharacterized protein conserved in bacteria Function unknown 56460536 Common - Transcriptional regulator, GntR family IL1428 137 COG1802 GntR, Transcriptional regulators Transcription 56460719 Common - Transposon related ORF, HTH transcriptional regulator IL1615 70 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 56460348 Common - Il-IS_2, transposase IL1239.1 64 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 56461342 Common eriC Chloride channel protein EriC IL2242 119 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 56460428 Common htpX heat shock protein HtpX IL1320 193 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 56460104 Common - Uncharacterized protein containing a von Willebrand factor type A (vWA) domain IL0996 93 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 56459850 Common - deoxyguanosinetriphosphate triphosphohydrolase-like protein IL0741 159 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 56461624 Common - putative toxin YafO IL2524 6 None None None 56459768 Common dsrE hypothetical protein IL0659 37 COG1553 DsrE, Uncharacterized conserved protein involved in intracellular sulfur reduction Inorganic ion transport and metabolism 56459610 Common - Il-IS_1, transposase IL0498.1 105 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 56460380 Common - hypothetical protein IL1272 3 None None None 56459362 Common - Polysaccharide deacetylase family protein IL0251 105 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 56459524 Common - Predicted ATPase IL0413 102 COG1485 COG1485, Predicted ATPase General function prediction only 56459652 Common - Acetyltransferase, isoleucine patch superfamily IL0543 82 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 56459659 Common - UDP-N-acetylglucosamine 2-epimerase IL0550 105 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 56460459 Common pyrF Orotidine-5'-phosphate decarboxylase IL1351 158 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 56459603 Common - Signal transduction histidine kinase (contains HAMP domain) IL0492 175 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 56460233 Common lytB 4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IL1125 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 56461313 Common epd D-erythrose 4-phosphate dehydrogenase IL2213 218 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 56461477 Common - Acetyltransferase domain (GNAT family) fused to predicted amidohydrolase (nitrilase family) IL2377 186 COG0388 COG0388, Predicted amidohydrolase General function prediction only 56460504 Common rplT 50S ribosomal protein L20 IL1396 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 56460963 Common - Enoyl-CoA hydratase/isomerase family protein IL1863 170 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 56460449 Common fabD Malonyl-CoA-[acyl-carrier-protein] transacylase IL1341 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 56460738 Common - Transcriptional regulator, MerR family IL1637 136 COG0789 SoxR, Predicted transcriptional regulators Transcription 56460117 Common - hypothetical protein IL1009 3 None None None 56460394 Common rmf Ribosome modulation factor IL1286 21 COG3130 Rmf, Ribosome modulation factor Translation, ribosomal structure and biogenesis 56460470 Common gph Phosphoglycolate phosphatase IL1362 216 COG0546 Gph, Predicted phosphatases General function prediction only 56459359 Common - predicted gluconate transport-associated protein IL0248 74 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 56461376 Common efp Translation elongation factor P IL2276 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 56459553 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase IL0442 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 56460496 Common phrB_1 Deoxyribodipyrimidine photolyase IL1388 133 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 56459744 Nonpathogen - hypothetical protein IL0635 1 None None None 56461516 Common - hypothetical protein IL2416 9 None None None 56459973 Common - DNA-binding transcriptional activator GcvA IL0865 184 COG0583 LysR, Transcriptional regulator Transcription 56459320 Common fpr Ferredoxin-NADP reductase IL0209 153 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 56461738 Common - alpha hemolysin-like protein IL2638 183 COG0759 COG0759, Uncharacterized conserved protein Function unknown 56460758 Common - Acetyltransferase domain (GNAT family) fused peptidase domain (C39 family) IL1657 40 COG0456 RimI, Acetyltransferases General function prediction only 56460059 Common - Uncharacterized conserved protein, Iojap family IL0951 200 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 56460240 Nonpathogen - hypothetical protein IL1132 1 None None None 56461598 Common - Uncharacterized conserved secreted or membrane protein IL2498 10 None None None 56459866 Common - Uncharacterized conserved protein containing predicted Zn-ribbon like domain IL0757 22 None None None 56461361 Common murC_2 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase IL2261 207 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 56459266 Common - Response regulator, LuxR family (CheY-HTH) IL0155 167 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 56460318 Common - Malate/L-lactate dehydrogenase family enzyme IL1210 67 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 56460183 Common gltB glutamate synthase subunit alpha IL1075 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 56460989 Common - hypothetical protein IL1889 2 None None None 56461705 Nonpathogen - hypothetical protein IL2605 1 None None None 56460265 Common - ABC-type uncharacterized transport system, ATPase component IL1157 249 COG4136 COG4136, ABC-type uncharacterized transport system, ATPase component General function prediction only 56459464 Common - Predicted thioesterase IL0353 61 COG0824 FcbC, Predicted thioesterase General function prediction only 56459731 Common - ATPase component of ABC transporters with duplicated ATPase domains IL0622 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 56460256 Common cheR Methylase of chemotaxis methyl-accepting proteins IL1148 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 56459194 Common - Short chain dehydrogenase/reductase family protein IL0083 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 56461449 Common tlyC Membrane hemolisin TlyC, contains CBS domains IL2349 215 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 56460155 Common nqrD Na(+)-translocating NADH-quinone reductase subunit D IL1047 76 COG1347 NqrD, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD Energy production and conversion 56460819 Common - Cytochrome c556 IL1718 28 COG3909 COG3909, Cytochrome c556 Energy production and conversion 56461511 Common ppiC Parvulin-like peptidyl-prolyl isomerase IL2411 144 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 56461657 Nonpathogen - hypothetical protein IL2557 1 None None None 56460350 Common - Co/Zn/Cd efflux system component IL1242 89 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 56461683 Common - Signal transduction histidine kinase, contains HAMP domain IL2583 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 56460572 Common - Thioredoxin related protein IL1464 62 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 56459124 Common slt Soluble lytic murein transglycosylase IL0012 161 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 56461296 Common - Predicted metal-dependent peptidase IL2196 24 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 56459673 Common - Nucleoside-diphosphate-sugar epimerase IL0564 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 56460452 Common rpmF 50S ribosomal protein L32 IL1344 64 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 56460812 Common - Uncharacterized conserved secreted or membrane protein IL1711 7 None None None 56461233 Common thiI thiamine biosynthesis protein ThiI IL2133 94 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 56461384 Common - 3-dehydroquinate dehydratase IL2284 169 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 56459496 Common cafA ribonuclease G IL0385 184 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 56459206 Common qseB_1 Response regulator (CheY,wHTH domains) IL0095 206 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 56459757 Common - hypothetical protein IL0648 18 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 56461122 Common pulH Type II secretory pathway, component PulH IL2022 15 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 56461545 Nonpathogen - hypothetical protein IL2445 1 None None None 56459132 Common smg hypothetical protein IL0020 39 COG2922 Smg, Uncharacterized protein conserved in bacteria Function unknown 56460731 Common - Unchararacterized conserved membrane protein IL1630 2 None None None 56461276 Common - Phosphodiesterase/alkaline phosphatase D IL2176 57 COG3540 PhoD, Phosphodiesterase/alkaline phosphatase D Inorganic ion transport and metabolism 56459114 Common dnaN DNA polymerase sliding clamp subunit IL0002 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 56460807 Common pabB P-aminobenzoate synthetase, component I IL1706 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 56460339 Common - hypothetical protein IL1231 8 None None None 56460359 Common - Cytochrome b561 family protein IL1251 40 COG3658 COG3658, Cytochrome b Energy production and conversion 56460625 Common - hypothetical protein IL1519 7 None None None 56460823 Common - DnaJ-related protein IL1722 14 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 56461607 Common - hypothetical protein IL2507 21 None None None 56460099 Common - Zn-dependent peptidase, insulinase family IL0991 189 COG1025 Ptr, Secreted/periplasmic Zn-dependent peptidases, insulinase-like Posttranslational modification, protein turnover, chaperones 56459401 Common - hypothetical protein IL0290 52 COG4681 COG4681, Uncharacterized protein conserved in bacteria Function unknown 56460553 Common - hypothetical protein IL1445 59 COG3825 COG3825, Uncharacterized protein conserved in bacteria Function unknown 56461715 Nonpathogen - Transcriptional regulator, Cro/CI/xre family IL2615 1 COG5606 COG5606, Uncharacterized conserved small protein Function unknown 56461156 Common - Plasmid maintenance system antidote protein IL2056 75 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 56460365 Common - Peptidase, M23/M37 family IL1257 141 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 56460742 Common - Co/Zn/Cd efflux system component IL1641 208 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 56460574 Common wrbA Multimeric flavodoxin WrbA IL1466 103 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 56459857 Common pcm Protein-L-isoaspartate carboxylmethyltransferase IL0748 156 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 56461069 Common - hypothetical protein IL1969 170 COG0344 COG0344, Predicted membrane protein Function unknown 56459259 Common sufE Cysteine desulfurase SufE subunit IL0148 96 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 56460482 Common - hypothetical protein IL1374 19 None None None 56459714 Common - hypothetical protein IL0605 158 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 56459301 Common hemN coproporphyrinogen III oxidase IL0190 204 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 56460560 Common - hypothetical protein IL1452 21 COG3092 COG3092, Uncharacterized protein conserved in bacteria Function unknown 56459584 Common - Il-IS_1, transposase IL0472.1 105 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 56459793 Common - hypothetical protein IL0684 12 None None None 56460694 Nonpathogen - hypothetical protein IL1590 2 None None None 56459421 Common - Secreted metal-dependent hydrolase, amidohydrolase family IL0310 73 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 56460249 Common flgH flagellar basal body L-ring protein IL1141 97 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 56459348 Common slmA nucleoid occlusion protein IL0237 60 COG1309 AcrR, Transcriptional regulator Transcription 56460092 Common - Predicted Zn-dependent protease related to HtpX IL0984 128 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 56459250 Nonpathogen - hypothetical protein IL0139 1 None None None 56459500 Common - hypothetical protein IL0389 61 COG3028 COG3028, Uncharacterized protein conserved in bacteria Function unknown 56461525 Common rph RNase PH IL2425 209 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 56459371 Common cyoA Cytochrome c oxidase, subunit II IL0260 153 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 56461673 Common - Iron-sulfur cluster-binding protein IL2573 77 COG0348 NapH, Polyferredoxin Energy production and conversion 56461249 Common yajC preprotein translocase subunit YajC IL2149 172 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 56460357 Common alkB Alkylated DNA repair protein IL1249 56 COG3145 AlkB, Alkylated DNA repair protein DNA replication, recombination, and repair 56460565 Nonpathogen - hypothetical protein IL1457 1 None None None 56460935 Common hisD Histidinol dehydrogenase IL1835 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 56461504 Common - ABC-type multidrug transport system, ATPase (two domains) and permease components IL2404 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 56461115 Common - Small-conductance mechanosensitive channel IL2015 214 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 56461124 Common pulF Type II secretory pathway, component PulF IL2024 148 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 56460982 Common deoA thymidine phosphorylase IL1882 118 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 56459341 Common - Fe-S-cluster domain IL0230 37 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 56459393 Common greB GreB IL0282 194 COG0782 GreA, Transcription elongation factor Transcription 56459662 Common - Nucleoside-diphosphate-sugar pyrophosphorylase IL0553 217 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 56459274 Common - 2OG-Fe(II) oxygenase superfamily protein IL0163 54 COG3491 PcbC, Isopenicillin N synthase and related dioxygenases General function prediction only 56460173 Common bfd Bacterioferritin-associated ferredoxin IL1065 32 COG2906 Bfd, Bacterioferritin-associated ferredoxin Inorganic ion transport and metabolism 56460654 Common - hypothetical protein IL1548 18 COG3141 COG3141, Uncharacterized protein conserved in bacteria Function unknown 56461058 Common ddg Lipid A biosynthesis lauroyl acyltransferase IL1958 85 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 56461048 Common pepA leucyl aminopeptidase IL1948 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 56460430 Common bioC Biotin synthesis protein IL1322 154 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 56460236 Common ileS Isoleucyl-tRNA synthetase IL1128 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 56460925 Common - hypothetical protein IL1825 34 COG3100 COG3100, Uncharacterized protein conserved in bacteria Function unknown 56459930 Common lysU Lysyl-tRNA synthetase class II IL0822 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 56459969 Common - isocitrate dehydrogenase IL0861 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 56460144 Common - Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA IL1036 40 COG4445 MiaE, Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 56459454 Common rplJ 50S ribosomal protein L10 IL0343 209 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 56460897 Common rnfD Predicted NADH:ubiquinone oxidoreductase, subunit RnfD IL1797 76 COG4658 RnfD, Predicted NADH:ubiquinone oxidoreductase, subunit RnfD Energy production and conversion 56461287 Nonpathogen - hypothetical protein IL2187 1 COG3096 MukB, Uncharacterized protein involved in chromosome partitioning Cell division and chromosome partitioning 56461303 Nonpathogen - Predicted glycosyltransferase IL2203 3 None None None 56459380 Common tdh L-threonine 3-dehydrogenase IL0269 209 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 56459186 Common dps_1 DNA-binding protein IL0075 77 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 56459554 Common - hypothetical protein IL0443 6 COG4701 COG4701, Uncharacterized protein conserved in bacteria Function unknown 161761290 Common astB succinylarginine dihydrolase IL1011 34 COG3724 AstB, Succinylarginine dihydrolase Amino acid transport and metabolism 56460135 Common - Dipeptidyl peptidase IV IL1027 115 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 56461393 Common - Signaling protein (EAL,CBS,GGDEF domains) IL2293 164 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 56460835 Common oadB Oxaloacetate decarboxylase, beta subunit IL1734 56 COG1883 OadB, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit Energy production and conversion 56459646 Common - Possible regulatory protein containing AAA-type ATPase domain IL0537 149 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 56459899 Common - hypothetical protein IL0791 4 None None None 56459261 Common sufA Fe-S cluster assembly scaffold protein IL0150 147 COG0316 IscA, Uncharacterized conserved protein Function unknown 56461263 Common cysK cysteine synthase A IL2163 222 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 56460321 Common speA arginine decarboxylase IL1213 72 COG1166 SpeA, Arginine decarboxylase (spermidine biosynthesis) Amino acid transport and metabolism 56461012 Common mnhG putative monovalent cation/H+ antiporter subunit G IL1912 64 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 56460892 Common - Predicted glycosyl transferase IL1792 21 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 56460944 Common - Glutathione S-transferase related protein, MAPEG superfamily IL1844 33 COG3788 COG3788, Uncharacterized relative of glutathione S-transferase, MAPEG superfamily General function prediction only 56460308 Common fliF flagellar MS-ring protein IL1200 125 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 56460618 Common lpxK Tetraacyldisaccharide-1-P 4'-kinase IL1512 130 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 56461041 Nonpathogen - Predicted secreted or membrane protein IL1941 1 None None None 56460440 Common prpD 2-methylcitrate dehydratase IL1332 56 COG2079 PrpD, Uncharacterized protein involved in propionate catabolism General function prediction only 56461619 Common - deoxyguanosinetriphosphate triphosphohydrolase-like protein IL2519 159 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 56459150 Common pheA Prephenate dehydratase IL0038 206 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 56461560 Common argS arginyl-tRNA synthetase IL2460 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 56460800 Nonpathogen - Predicted secreted protein IL1699 1 None None None 56460217 Common - hypothetical protein IL1109 7 None None None 56459232 Common - hypothetical protein IL0121 19 None None None 56461105 Common - Multidomain protein contains Na+/proline symporter PutP-like domain, sensory histidine kinase and receiver domain IL2005 220 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 56460223 Common cheZ Chemotaxis protein CheZ IL1115 43 COG3143 CheZ, Chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 56459176 Common - Predicted transcription negative regulator IL0065 34 COG3806 ChrR, Transcriptional activator Transcription 56460489 Common - hypothetical protein IL1381 23 None None None 56461418 Common argD bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein IL2318 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 56460396 Common lonB ATP-dependent serine protease LA IL1288 144 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 56459308 Common - Probable regulator of cell morphogenesis and NO signaling IL0197 45 COG2846 COG2846, Regulator of cell morphogenesis and NO signaling Cell division and chromosome partitioning 56461266 Common cfa cyclopropane fatty acyl phospholipid synthase IL2166 130 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 56461427 Common prlC Oligopeptidase A IL2327 123 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 56459334 Common - hypothetical protein IL0223 26 COG3068 COG3068, Uncharacterized protein conserved in bacteria Function unknown 56460477 Nonpathogen - hypothetical protein IL1369 1 None None None 56461015 Common rpsQ Ribosomal protein S17 IL1915 240 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 56460796 Common - Rhodanese-related sulfurtransferase IL1695 158 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 56461193 Common gcvH glycine cleavage system protein H IL2093 186 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 56461075 Common proC Pyrroline-5-carboxylate reductase IL1975 215 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 56459781 Common - arginyl-tRNA-protein transferase IL0672 85 COG2935 COG2935, Putative arginyl-tRNA:protein arginylyltransferase Posttranslational modification, protein turnover, chaperones 56460780 Common - Alpha keto acid dehydrogenase complex, E1 component, beta subunit IL1679 219 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 56460403 Common - RND family efflux transporter IL1295 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 56459385 Common natA_1 ABC-type Na+ efflux pump, ATPase component IL0274 249 COG4152 COG4152, ABC-type uncharacterized transport system, ATPase component General function prediction only 56459803 Common asnC DNA-binding transcriptional regulator AsnC IL0694 143 COG1522 Lrp, Transcriptional regulators Transcription 56459212 Common - Outer membrane protein IL0101 51 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 56461695 Common plcC Phospholipase C IL2595 35 COG3511 PlcC, Phospholipase C Cell envelope biogenesis, outer membrane 56459808 Common arsA Probable arsenical pump-driving ATPase IL0699 90 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 56460293 Common glnB Nitrogen regulatory protein PII IL1185 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 56459216 Common - Predicted phosphatase IL0105 115 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 56461573 Common aroB 3-dehydroquinate synthetase IL2473 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 56459915 Common pdxJ pyridoxal phosphate biosynthetic protein PdxJ IL0807 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 56460872 Common - Transcriptional regulator, LysR family IL1772 171 COG0583 LysR, Transcriptional regulator Transcription 56459436 Common - hypothetical protein IL0325 30 COG3089 COG3089, Uncharacterized protein conserved in bacteria Function unknown 56460634 Common - Na+/proline symporter IL1528 163 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 56459443 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase IL0332 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 56461051 Common - hypothetical protein IL1951 23 COG3076 COG3076, Uncharacterized protein conserved in bacteria Function unknown 56459563 Common pulE Type II secretory pathway, ATPase PulE IL0452 221 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 56460595 Common - Acyl-CoA dehydrogenase IL1487 148 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 56461630 Common recD ATP-dependent exoDNAse (exonuclease V), alpha subunit, superfamily I helicase IL2530 128 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 56461335 Common tap Methyl-accepting chemotaxis protein (contains HAMP domain) IL2235 167 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 56459892 Nonpathogen - Predicted secreted protein IL0783 1 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 56460977 Nonpathogen - Uncharacterized conserved membrane protein, smp family IL1877 1 COG3726 AhpA, Uncharacterized membrane protein affecting hemolysin expression General function prediction only 56459813 Nonpathogen - Predicted secreted or membrane protein IL0704 1 None None None 56461072 Common phoD Phosphodiesterase/alkaline phosphatase D family enzyme IL1972 7 COG3540 PhoD, Phosphodiesterase/alkaline phosphatase D Inorganic ion transport and metabolism 56461497 Common phnA Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism IL2397 75 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 56460228 Common flhA flagellar biosynthesis protein A IL1120 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 56459595 Common - Acetyltransferase, GNAT family IL0484 4 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 56461666 Common dnaE_2 DNA polymerase III alpha subunit IL2566 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 56460970 Common ribD Riboflavin-specific deaminase/reductase IL1870 225 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 56461181 Common - Alpha-hemolysin family protein IL2081 41 COG0759 COG0759, Uncharacterized conserved protein Function unknown 56461639 Common - Threonine aldolase putative IL2539 78 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 56460015 Nonpathogen - Hypothetical protein, IL_1 family IL0907 1 None None None 56460041 Common - Cyanoglobin family protein IL0933 27 COG2346 COG2346, Truncated hemoglobins General function prediction only 56460667 Common osmY Osmotically inducible periplasmic protein IL1561 47 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 56460611 Common sdhA succinate dehydrogenase flavoprotein subunit IL1505 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 56461534 Common cpxR Response regulator (CheY,wHTH domains) IL2434 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 56459395 Nonpathogen - hypothetical protein IL0284 1 None None None 56459685 Common - hypothetical protein IL0576 2 None None None 56459193 Common - Xylosidase/arabinosidase IL0082 21 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 56459243 Common - Glycosyltransferase IL0132 152 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 56460088 Common carB carbamoyl phosphate synthase large subunit IL0980 237 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 56460077 Common nusA transcription elongation factor NusA IL0969 216 COG0195 NusA, Transcription elongation factor Transcription 56460603 Nonpathogen - Probable lysophospholipase, alpha/beta hydrolase superfamily IL1497 1 COG2267 PldB, Lysophospholipase Lipid metabolism 56461643 Nonpathogen - hypothetical protein IL2543 3 None None None 56459818 Common dcd deoxycytidine triphosphate deaminase IL0709 150 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 56461323 Common hepA ATP-dependent helicase HepA IL2223 139 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 56461308 Common - Transcriptional regulator of Pi transport IL2208 37 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 56460278 Common - hypothetical protein IL1170 8 None None None 56460172 Common - Ca2+/Na+ antiporter IL1064 128 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 56460195 Common ruvC Holliday junction resolvasome, endonuclease subunit IL1087 194 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 56460752 Common dgkA Diacylglycerol kinase IL1651 56 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 56459142 Common - hypothetical protein IL0030 14 None None None 56460955 Common - TonB-like periplasmic protein IL1855 41 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 56459315 Common dinP DinP IL0204 181 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 56460662 Common ilvE branched-chain amino acid aminotransferase IL1556 200 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 56460326 Common - Cation transport ATPase IL1218 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 56461672 Common - predicted kinase IL2572 53 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 56459572 Common pepO Secreted zinc metalloproteinase IL0461 63 COG3590 PepO, Predicted metalloendopeptidase Posttranslational modification, protein turnover, chaperones 56459845 Common sapD ABC-type antimicrobial peptide transport system, ATPase component IL0736 249 COG4170 SapD, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 56460766 Common fadE acyl-CoA dehydrogenase IL1665 149 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 56459611 Common - Signalling protein containing EAL domain IL0500 163 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 56460614 Common gltA Citrate synthase IL1508 194 COG0372 GltA, Citrate synthase Energy production and conversion 56460685 Common fhuE_1 Outer membrane receptor for ferric siderophore IL1581 97 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 56460911 Nonpathogen - hypothetical protein IL1811 2 None None None 56460779 Common - dihydrolipoamide acetyltransferase IL1678 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 56460288 Common - Phosphatidylserine synthase IL1180 151 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 56461238 Common dxs 1-deoxy-D-xylulose-5-phosphate synthase IL2138 222 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 56459627 Common - hypothetical protein IL0516 18 None None None 56459444 Common hfq Host factor I-like protein IL0333 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 56460160 Common bolA Predicted transcriptional regulator, BolA superfamily IL1052 103 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 56459976 Common - Enoyl-CoA hydratase/isomerase family protein IL0868 131 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 56459620 Common - Il-IS_3, transposase IL0508.1 83 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 56460006 Common smpB SsrA-binding protein IL0898 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 56461240 Common thiL Thiamine monophosphate kinase IL2140 189 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 56459410 Common - hypothetical protein IL0299 35 COG3619 COG3619, Predicted membrane protein Function unknown 56459357 Common bioH Alpha/beta superfamily hydrolase IL0246 170 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 56460218 Common cheW_1 Chemotaxis protein CheW IL1110 141 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 56460639 Common acnA aconitate hydratase IL1533 223 COG1048 AcnA, Aconitase A Energy production and conversion 56459991 Common - hypothetical protein IL0883 2 None None None 56461405 Common - HlyD family secretion protein IL2305 173 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 56460048 Common - Predicted permease, DMT superfamily IL0940 113 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 56461551 Common hutU urocanate hydratase IL2451 97 COG2987 HutU, Urocanate hydratase Amino acid transport and metabolism 56460180 Common - Predicted glycosyltransferase IL1072 7 None None None 56459296 Common - hypothetical protein IL0185 6 None None None 56460336 Common - Outer membrane protein IL1228 111 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 56459834 Common phhA phenylalanine 4-monooxygenase IL0725 45 COG3186 COG3186, Phenylalanine-4-hydroxylase Amino acid transport and metabolism 56460529 Common - Methyl-accepting chemotaxis protein IL1421 153 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 56460802 Common zipA Secreted cell division protein IL1701 42 COG3115 ZipA, Cell division protein Cell division and chromosome partitioning 56460442 Nonpathogen - hypothetical protein IL1334 1 None None None 56461392 Common purD Phosphoribosylamine-glycine ligase IL2292 232 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 56459474 Common mshI_1 Type II secretory pathway component IL0363 14 None None None 56459441 Common amiB N-acetylmuramoyl-L-alanine amidase IL0330 172 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 56459998 Nonpathogen - hypothetical protein IL0890 1 COG5510 COG5510, Predicted small secreted protein Function unknown 56461316 Common - hypothetical protein IL2216 206 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 56459631 Common siaA UDP-N-acetylglucosamine 2-epimerase IL0520 132 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 56459264 Common sufC Cysteine desulfurase activator ATPase IL0153 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 56460066 Common - hypothetical protein IL0958 45 COG2921 COG2921, Uncharacterized conserved protein Function unknown 56460857 Common trpA Tryptophan synthase alpha chain IL1756 214 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 56460526 Common - Choline-glycine betaine transporter IL1418 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 56459130 Common def N-formylmethionyl-tRNA deformylase IL0018 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 56460231 Nonpathogen - Type II secretion pathway related protein IL1123 1 None None None 56459712 Common - hypothetical protein IL0603 36 COG4103 COG4103, Uncharacterized protein conserved in bacteria Function unknown 56460341 Common copC hypothetical protein IL1233 28 COG2372 CopC, Uncharacterized protein, homolog of Cu resistance protein CopC General function prediction only 56460951 Common - Chemotaxis protein CheY IL1851 219 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 56461026 Common - Zn-dependent dipeptidase IL1926 104 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 56460623 Common - ABC-type transport system, involved in lipoprotein release, ATPase component IL1517 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 56459466 Common - Permease of the major facilitator superfamily IL0355 118 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 56460100 Common - Signaling protein with a ligand-binding sensor domain, PAS, GGDEF and EAL domains IL0992 193 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 56459419 Common - hypothetical protein IL0308 106 COG2606 EbsC, Uncharacterized conserved protein Function unknown 56461719 Common atpD F0F1 ATP synthase subunit beta IL2619 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 56460102 Common fadI 3-ketoacyl-CoA thiolase IL0994 175 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 56460162 Common - hypothetical protein IL1054 14 None None None 56460137 Common - Probable aminopeptidase IL1029 52 COG2234 Iap, Predicted aminopeptidases General function prediction only 56459597 Common gsk Sugar kinase, ribokinase family IL0486 199 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 56460374 Common gapC glyceraldehyde-3-phosphate dehydrogenase IL1266 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 56460996 Common secY preprotein translocase subunit SecY IL1896 218 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 56460592 Nonpathogen - Predicted secreted or membrane protein IL1484 1 None None None 56459698 Common - Predicted extracellular metal-dependent peptidase IL0589 5 None None None 56459581 Common yfeK Dyp-type peroxidase family protein IL0470 49 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 56460462 Common himD Bacterial nucleoid DNA-binding protein, IHF beta subunit IL1354 207 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 56461002 Common rpsH Ribosomal protein S8 IL1902 230 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 56460915 Common - Acetyltransferase, GNAT family IL1815 57 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 56461467 Common tatD Mg-dependent DNase IL2367 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 56460421 Common - Cupin superfamily protein IL1313 60 COG2850 COG2850, Uncharacterized conserved protein Function unknown 56460773 Common abgT_3 Probable p-aminobenzoyl-glutamate transporter IL1672 38 COG2978 AbgT, Putative p-aminobenzoyl-glutamate transporter Coenzyme metabolism 56461480 Common spoT (p)ppGpp synthetase I IL2380 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 56459728 Common - Outer membrane protein IL0619 26 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 56461415 Common - hypothetical protein IL2315 7 None None None 56460412 Common - hypothetical protein IL1304 44 COG2836 COG2836, Uncharacterized conserved protein Function unknown 56460074 Common truB tRNA pseudouridine 5S synthase IL0966 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 56460542 Common gloA Lactoylglutathione lyase IL1434 128 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 56460426 Common - hypothetical protein IL1318 23 None None None 56461311 Common gatY fructose-1,6-bisphosphate aldolase IL2211 176 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 56459942 Common fabZ 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase IL0834 186 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 56461547 Common rbn ribonuclease BN IL2447 152 COG1295 Rbn, Predicted membrane protein Function unknown 56461138 Common ndk Nucleoside diphosphate kinase IL2038 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 56461670 Common - Small-conductance mechanosensitive channel IL2570 77 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 56460125 Common truA tRNA pseudouridine synthase A IL1017 237 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 56461294 Common - CII phage-related protein IL2194 11 None None None 56460883 Common - Predicted Zn-binding protein IL1783 87 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 56459935 Nonpathogen - hypothetical protein IL0827 1 None None None 56461253 Common - Response regulator, LuxR family (CheY, HTH domains) IL2153 175 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 56461402 Common psd Phosphatidylserine decarboxylase IL2302 97 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 56461066 Common cca tRNA nucleotidyltransferase IL1966 182 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 56461612 Common - Uncharacterized iron-regulated membrane protein IL2512 48 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 56460880 Common - Outer membrane protein, porin family IL1780 6 None None None 56460670 Common - Predicted S-adenosylmethionine-dependent methyltransferase IL1564 49 None None None 56460193 Common ruvB Holliday junction DNA helicase B IL1085 237 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 56461421 Common pabA P-aminobenzoate synthetase, component II IL2321 240 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 56460389 Common - hypothetical protein IL1281 17 None None None 56461513 Common - Uncharacterized conserved metal-binding protein IL2413 38 COG4338 COG4338, Uncharacterized protein conserved in bacteria Function unknown 56460582 Common - hypothetical protein IL1474 8 None None None 56460837 Nonpathogen oadG oxaloacetate decarboxylase subunit gamma IL1736 1 COG3630 OadG, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, gamma subunit Energy production and conversion 56461485 Nonpathogen - Photoactive yellow protein IL2385 7 None None None 56459859 Common - hypothetical protein IL0750 80 COG0585 COG0585, Uncharacterized conserved protein Function unknown 56461215 Common - Periplasmic protein TonB IL2115 26 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 56460268 Common merA_1 Mercuric reductase, membrane-associated IL1160 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 56460057 Common holA DNA polymerase III, delta subunit IL0949 68 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 56461371 Common - Outer membrane protein IL2271 102 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 56459139 Common engB GTPase EngB IL0027 181 COG0218 COG0218, Predicted GTPase General function prediction only 56461278 Common - Putative lipase/esterase IL2178 42 COG0657 Aes, Esterase/lipase Lipid metabolism 56460830 Common - Mg/Co transporter IL1729 219 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 56460163 Common - hypothetical protein IL1055 20 COG3009 COG3009, Uncharacterized protein conserved in bacteria Function unknown 56459140 Common - Cytochrome c4 IL0028 60 COG2863 COG2863, Cytochrome c553 Energy production and conversion 56459733 Common - hypothetical protein IL0624 13 COG4758 COG4758, Predicted membrane protein Function unknown 56461413 Common comJ Transformation competence-related protein ComJ IL2313 86 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 56459373 Common lexA LexA repressor IL0262 172 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 56459864 Common - Signaling protein with a MHYT sensor domain, PAS, GGDEF and EAL domains IL0755 176 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 56460710 Common - Sugar efflux permease, MFS-like IL1606 131 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 56459490 Common mshQ Type II secretory pathway component IL0379 35 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 56459531 Common sspB ClpXP protease specificity-enhancing factor IL0420 64 COG2969 SspB, Stringent starvation protein B General function prediction only 56459538 Common mraZ hypothetical protein IL0427 145 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 56461088 Common - Predicted glycosyltransferase IL1988 14 None None None 56459888 Common czcC Co/Zn/Cd efflux system component IL0779 71 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 56460726 Nonpathogen - hypothetical protein IL1623 1 COG4026 COG4026, Uncharacterized protein containing TOPRIM domain, potential nuclease General function prediction only 56460809 Common sdaA L-serine deaminase IL1708 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 56460259 Common flgM Negative regulator of flagellin synthesis IL1151 12 COG2747 FlgM, Negative regulator of flagellin synthesis (anti-sigma28 factor) Transcription / Cell motility and secretion / Intracellular trafficking and secretion 56460435 Common asnC asparaginyl-tRNA synthetase IL1327 224 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 56459196 Nonpathogen - Uncharacterized conserved coiled coil protein IL0085 13 None None None 56459671 Common - Nucleoside-diphosphate-sugar epimerase IL0562 137 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 56461356 Common gadB Glutamate decarboxylase putative IL2256 117 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 56461713 Common tnsA Transposon Tn7 transposition protein tnsA IL2613 17 None None None 56459761 Common pgsA Phosphatidylglycerophosphate synthase IL0652 203 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 56459408 Common - Secreted metal-dependent hydrolase, amidohydrolase family IL0297 20 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 56461094 Common - Thioredoxin domain-containing protein IL1994 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 56460534 Common prpC methylcitrate synthase IL1426 194 COG0372 GltA, Citrate synthase Energy production and conversion 56459852 Common cinA Competence/damage-inducible protein IL0743 192 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 56460316 Common - Response regulator containing a CheY-like receiver domain and an HD-GYP domain IL1208 114 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 56459116 Common gyrB DNA gyrase subunit B IL0004 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 56460867 Common - ABC-type transport system, permease component IL1766 87 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 56461100 Common - Carboxynorspermidine decarboxylase IL2000 58 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 56459149 Common - Phospholipase/carboxylesterase family protein IL0037 99 COG0400 COG0400, Predicted esterase General function prediction only 56460946 Common htpG heat shock protein 90 IL1846 150 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 56461245 Common - hypothetical protein IL2145 12 None None None 56459424 Common - Signaling protein with membrane-bound sensor domain and an ATPase domain IL0313 87 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 56461127 Common pulC Type II secretory pathway, component PulC IL2027 33 COG3031 PulC, Type II secretory pathway, component PulC Intracellular trafficking and secretion 56459352 Common rpmB Ribosomal protein L28 IL0241 158 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 56459746 Nonpathogen - prophage maintenance system killer protein Doc-like protein IL0637 1 COG3654 Doc, Prophage maintenance system killer protein General function prediction only 56459650 Common rffG DTDP-D-glucose 4,6-dehydratase IL0541 232 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 56459511 Common - 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase IL0400 102 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 56460928 Common - Alpha/beta superfamily hydrolase IL1828 56 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 56459666 Common - Glycosyltransferase IL0557 138 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 56459657 Common - Predicted nucleoside-diphosphate sugar epimerase IL0548 136 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 56460111 Common lon ATP-dependent Lon protease IL1003 213 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 56459970 Common - SAM-dependent methyltransferase IL0862 46 COG2933 COG2933, Predicted SAM-dependent methyltransferase General function prediction only 56459327 Common - hypothetical protein IL0216 6 None None None 56461173 Common - hypothetical protein IL2073 16 None None None 56461344 Common pyrB aspartate carbamoyltransferase IL2244 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 56459778 Common pntA Alanine dehydrogenase IL0669 167 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 56459841 Common pspF Transcriptional regulator, AtoC family (AAA,HTH domains) IL0732 169 COG1221 PspF, Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain Transcription / Signal transduction mechanisms 56459155 Nonpathogen - Uncharacterized conserved membrane or secreted protein IL0043 1 None None None 56461044 Common - Uncharacterized conserved protein, containing 2 CBS domains IL1944 13 None None None 56459518 Common - STAS domain IL0407 7 COG3113 COG3113, Predicted NTP binding protein (contains STAS domain) General function prediction only 56460961 Common - Histone deacetylase/AcuC/AphA family protein IL1861 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 56461576 Common elaA Acetyltransferase, GNAT family IL2476 81 COG2153 ElaA, Predicted acyltransferase General function prediction only 56461663 Common - Cytochrome B561 IL2563 90 COG3038 CybB, Cytochrome B561 Energy production and conversion 56461120 Common pulJ Type II secretory pathway, component PulJ IL2020 33 COG4795 PulJ, Type II secretory pathway, component PulJ Intracellular trafficking and secretion 56459558 Common - Uncharacterized zinc finger protein IL0447 62 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 56459522 Common degQ Periplasmic trypsin-like serine protease IL0411 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 56461588 Common - Outer membrane protein IL2488 109 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 56459551 Common ftsA Cell division ATPase, FtsA IL0440 176 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 56459881 Common - Enolase IL0772 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 56460578 Common - Permease of the major facilitator superfamily IL1470 63 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 56460200 Common - SAM-dependent methyltransferase IL1092 87 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 56460392 Common - ATPase component of ABC transporters with duplicated ATPase domains IL1284 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 56459687 Common guaB inositol-5-monophosphate dehydrogenase IL0578 239 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 56461686 Common - Glutathione S-transferase related protein IL2586 17 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 56460242 Common fliD Flagellar capping protein IL1134 88 COG1345 FliD, Flagellar capping protein Cell motility and secretion 56459364 Common cyoE protoheme IX farnesyltransferase IL0253 177 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 56461454 Common - Permease of the major facilitator superfamily IL2354 11 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 56459959 Common - hypothetical protein IL0851 10 None None None 56459806 Common cstA Carbon starvation regulatory protein IL0697 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 56460717 Common - Superfamily I DNA/RNA helicase IL1613 95 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 56460109 Common - Periplasmic parvulin-like peptidyl-prolyl isomerase IL1001 163 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 56461601 Common - Ferredoxin-NADP reductase IL2501 113 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 56461285 Nonpathogen - hypothetical protein IL2185 1 None None None 56460656 Common - Conserved domain associated with flavoprotein oxygenase, DIM6/NTAB family IL1550 47 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 56459226 Common hmuV ABC-type hemin transport system, ATPase component IL0115 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 56459239 Common - acyl carrier protein IL0128 54 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 56461110 Common ppk polyphosphate kinase IL2010 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 161761292 Common ampD N-acetyl-anhydromuranmyl-L-alanine amidase IL0455 108 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 56459570 Common aceF dihydrolipoamide acetyltransferase IL0459 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 56461129 Common hslO Hsp33-like chaperonin IL2029 134 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 56460844 Common - RNA pseudouridylate synthase-family protein IL1743 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 56459355 Nonpathogen - Uncharacterized conserved secreted or membrane protein IL0244 1 None None None 56460899 Common rnfE SoxR-reducing system protein RsxE IL1799 76 COG4660 RnfE, Predicted NADH:ubiquinone oxidoreductase, subunit RnfE Energy production and conversion 56459198 Nonpathogen - Predicted membrane protein IL0087 1 None None None 56459234 Common - UDP-glucose 4-epimerase IL0123 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 56459230 Nonpathogen - hypothetical protein IL0119 11 COG0392 COG0392, Predicted integral membrane protein Function unknown 56460590 Nonpathogen - Predicted membrane protein IL1482 1 None None None 56461261 Common - Acetyltransferase, GNAT family IL2161 133 COG0456 RimI, Acetyltransferases General function prediction only 56459245 Common hutH_1 Histidine ammonia-lyase IL0134 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 56459547 Common murG UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase IL0436 208 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 56459513 Common - Transcriptional regulator, TetR family IL0402 50 COG1309 AcrR, Transcriptional regulator Transcription 56460750 Common - Membrane hydrolase of alkaline phosphatase superfamily IL1649 64 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 56461305 Common tgt tRNA-guanine transglycosylase IL2205 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 56461453 Nonpathogen - Predicted membrane protein IL2353 1 None None None 56460234 Common slpA FKBP-type peptidyl-prolyl cis-trans isomerase IL1126 128 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 56459664 Common - UDP-glucose:glucosyl LPS a 1,2-glucosyltransferase IL0555 5 None None None 56460705 Common - Transcriptional regulator, TetR family IL1601 111 COG1309 AcrR, Transcriptional regulator Transcription 56459883 Common - Co/Zn/Cd efflux system component IL0774 57 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 56460050 Common - Phosphate starvation-inducible protein PhoH IL0942 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 56460664 Common - Uncharacterized conserved protein, ElaB family IL1558 9 COG4575 ElaB, Uncharacterized conserved protein Function unknown 56459579 Common acnB bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase IL0468 220 COG1049 AcnB, Aconitase B Energy production and conversion 56460175 Common - Bacterioferritin (cytochrome b1) IL1067 107 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 56459189 Common - hypothetical protein IL0078 49 COG3735 COG3735, Uncharacterized protein conserved in bacteria Function unknown 56459336 Common - N6-adenine-specific methylase IL0225 211 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 56459706 Common murI glutamate racemase IL0597 189 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 56461087 Common kdtA 3-deoxy-D-manno-octulosonic-acid transferase IL1987 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 56461395 Common - Probable lipoprotein IL2295 13 None None None 56459397 Common - RelE-like protein IL0286 53 COG4115 COG4115, Uncharacterized protein conserved in bacteria Function unknown 56461010 Common mnhE Multisubunit Na+/H+ antiporter, MnhE subunit IL1910 73 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 56459222 Common - High-affinity Fe2+/Pb2+ permease IL0111 75 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 56460221 Common cheB chemotaxis-specific methylesterase IL1113 215 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 56461434 Common - hypothetical protein IL2334 4 None None None 56460680 Common - hypothetical protein IL1574 24 COG3739 COG3739, Uncharacterized integral membrane protein Function unknown 56460894 Common rnfA Na(+)-translocating NADH-quinone reductase subunit E IL1794 76 COG4657 RnfA, Predicted NADH:ubiquinone oxidoreductase, subunit RnfA Energy production and conversion 56461107 Common acs AMP-(fatty) acid ligase IL2007 216 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 56460306 Common fliH flagellar assembly protein H IL1198 48 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 56460034 Common hemA Glutamyl-tRNA reductase IL0926 184 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 56460215 Nonpathogen - hypothetical protein IL1107 1 None None None 56461077 Common - hypothetical protein IL1977 13 None None None 56461166 Common - hypothetical protein IL2066 23 None None None 56459346 Common secB Preprotein translocase subunit SecB IL0235 108 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 56461580 Common - Transporter, LysE family IL2480 73 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 56459468 Common - Transcriptional regulator, MarR family IL0357 69 COG1846 MarR, Transcriptional regulators Transcription 56461632 Common recC Exonuclease V gamma subunit IL2532 66 COG1330 RecC, Exonuclease V gamma subunit DNA replication, recombination, and repair 56460484 Common smtA SAM-dependent methyltransferase IL1376 101 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 56460740 Common - Membrane-fusion protein, RND family efflux system component IL1639 130 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 56461693 Common glpR Probable repressor of the glycerol-3-phosphate regulon IL2593 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 56460016 Nonpathogen - hypothetical protein IL0908 1 None None None 56461651 Common uvrD DNA-dependent helicase II IL2551 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 56459847 Common putP Na+/proline symporter IL0738 179 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 56460555 Common - Hybrid sensor histidine kinase IL1447 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 56460405 Common ccoN Cbb3-type cytochrome oxidase, subunit 1 IL1297 144 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 56459540 Common ftsL Cell division protein, FtsL IL0429 38 COG3116 FtsL, Cell division protein Cell division and chromosome partitioning 56460923 Common - hypothetical protein IL1823 74 COG2983 COG2983, Uncharacterized conserved protein Function unknown 56460669 Common - hypothetical protein IL1563 29 COG3428 COG3428, Predicted membrane protein Function unknown 56461502 Common - hypothetical protein IL2402 6 None None None 56459303 Common - Collagenase family protease IL0192 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 56459582 Common argR arginine repressor IL0471 77 COG1438 ArgR, Arginine repressor Transcription 56460094 Common dnaK Molecular chaperone (HSP70) IL0986 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 56460371 Common pykA Pyruvate kinase II, glucose stimulated IL1263 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 56461117 Common pulM Type II secretory pathway, component PulM IL2017 5 COG3149 PulM, Type II secretory pathway, component PulM Intracellular trafficking and secretion 56460645 Common - Signaling protein IL1539 161 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 56461225 Common aCR3 Arsenite efflux pump ACR3 IL2125 125 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 56461523 Common - DNA-directed RNA polymerase specialized sigma factor IL2423 155 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 56459904 Common - Alcohol dehydrogenase IL0796 174 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 56459822 Common - hypothetical protein IL0713 45 COG3785 COG3785, Uncharacterized conserved protein Function unknown 56459680 Common - hypothetical protein IL0571 9 None None None 56460001 Common - N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase IL0893 215 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 56461658 Common hemC porphobilinogen deaminase IL2558 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 56459894 Common serB_1 Phosphoserine phosphatase IL0785 23 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 56459502 Common - Mg/Co/Ni transporter MgtE (contains CBS domain) IL0391 172 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 56460825 Common trmD tRNA (guanine-N(1)-)-methyltransferase IL1724 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 56459251 Common - 3-oxoacyl-(acyl carrier protein) synthase I IL0140 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 56459913 Common - SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase IL0805 198 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 56461571 Common hofQ Type II secretory pathway, component PulJ IL2471 140 COG4796 HofQ, Type II secretory pathway, component HofQ Intracellular trafficking and secretion 56459160 Common - hypothetical protein IL0048 2 None None None 56460567 Common - Uncharacterized lipoprotein IL1459 31 COG3317 NlpB, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 56460437 Common sppA Periplasmic serine protease, ClpP family IL1329 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 56461417 Common - Arginine N-succinyltransferase IL2317 37 COG3138 AstA, Arginine/ornithine N-succinyltransferase beta subunit Amino acid transport and metabolism 56459947 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase IL0839 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 56460081 Common mrsA Phosphomannomutase family enzyme IL0973 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 56460506 Common infC translation initiation factor IF-3 IL1398 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 56460206 Common - TPR-containg protein IL1098 55 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 56460150 Common nifS NifS IL1042 236 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 56461614 Common fhuA Outer membrane protein IL2514 112 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 56459191 Common - OsmC-like organic hydroperoxide reductase IL0080 88 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 56459184 Common - hypothetical protein IL0073 19 None None None 56461536 Common glnL Nitrogen-specific sensor histidine kinase IL2436 208 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 56459423 Common - ABC-type multidrug transport system, ATPase component IL0312 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 56460276 Common - hypothetical protein IL1168 29 COG4446 COG4446, Uncharacterized protein conserved in bacteria Function unknown 56461034 Common - hypothetical protein IL1934 21 COG3595 COG3595, Uncharacterized conserved protein Function unknown 56460090 Common dapB Dihydrodipicolinate reductase IL0982 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 56459622 Common - PAS domain containing signalling protein IL0511 17 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 56461024 Common rplC Ribosomal protein L3 IL1924 236 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 56461202 Common - 5-formyltetrahydrofolate cyclo-ligase family protein IL2102 189 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 56459708 Common - Cystathionine gamma-synthase IL0599 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 56460352 Nonpathogen - Predicted secreted protein IL1244 1 COG3404 COG3404, Methenyl tetrahydrofolate cyclohydrolase Amino acid transport and metabolism 56460544 Common - Kef-type K+ transport system, NAD-binding component IL1436 33 None None None 56459536 Common - Tetrapyrrole methylase family protein IL0425 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 56460782 Common - succinylglutamate desuccinylase IL1681 24 COG2988 COG2988, Succinylglutamate desuccinylase Amino acid transport and metabolism 56461559 Common ftsN Cell division protein, FtsN IL2459 34 COG3087 FtsN, Cell division protein Cell division and chromosome partitioning 56461400 Common orn oligoribonuclease IL2300 88 COG1949 Orn, Oligoribonuclease (3'->5' exoribonuclease) RNA processing and modification 56459456 Common rpoB DNA-directed RNA polymerase beta subunit IL0345 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 56461146 Common - hypothetical protein IL2046 2 None None None 56460787 Common - Signaling protein with a GGDEF domain IL1686 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 56461591 Common - Transcriptional regulator, LysR family IL2491 167 COG0583 LysR, Transcriptional regulator Transcription 56460011 Common - possible Flp pilus assembly protein CpaF IL0903 165 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 56461060 Common - Uncharacterized protein containg phosphate binding CYTH domain and associated CHAD domain IL1960 59 COG3025 COG3025, Uncharacterized conserved protein Function unknown 56459204 Common - short chain dehydrogenase IL0093 229 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 56460584 Common fur ferric uptake regulator IL1476 199 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 56460283 Common btuB Outer membrane protein IL1175 103 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 56461236 Nonpathogen xseB Exonuclease VII, small subunit IL2136 1 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 56460616 Common kdsB 3-deoxy-manno-octulosonate cytidylyltransferase IL1510 148 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 161761287 Common spoU tRNA guanosine-2'-O-methyltransferase IL2375 192 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 56461645 Common - Signaling protein IL2545 160 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 56459167 Nonpathogen - hypothetical protein IL0055 1 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 56461151 Common - Cytochrome B561 IL2051 85 COG3038 CybB, Cytochrome B561 Energy production and conversion 56461171 Common - hypothetical protein IL2071 11 None None None 56460027 Common - K+ transport system membrane component IL0919 136 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 56461700 Nonpathogen - Possible Zn-finger protein IL2600 1 None None None 56461231 Common srmB ATP-dependent RNA helicase SrmB IL2131 237 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 56460079 Common secG Biopolymer transport protein IL0971 117 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 56459379 Common glpE Rhodanese-related sulfurtransferase IL0268 123 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 56461056 Common - NTP pyrophosphohydrolase, NUDIX family IL1956 85 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 56459310 Common - Conserved secreted Zn-dependent enzyme from deacylase/carboxypeptidase superfamily IL0199 16 None None None 56459629 Common siaB CMP-sialic acid synthetase IL0518 73 COG1083 NeuA, CMP-N-acetylneuraminic acid synthetase Cell envelope biogenesis, outer membrane 56460908 Common - Beta-lactamase class D (N-terminal domain) fused to uncharacterized conserved domain IL1808 45 COG2602 COG2602, Beta-lactamase class D Defense mechanisms 56459218 Nonpathogen - hypothetical protein IL0107 3 None None None 56461255 Common - GntP family permease IL2155 34 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 56459811 Common acrB Probable acriflavine resistance protein B, RND family efflux system component IL0702 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 56459481 Common mshE Type II secretory pathway, ATPase IL0370 218 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 56460517 Common - hypothetical protein IL1409 10 None None None 56461707 Common - Predicted signaling protein with an ATPase domain IL2607 38 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 56461154 Common - DNA ligase IL2054 31 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 56459433 Common udhA soluble pyridine nucleotide transhydrogenase IL0322 245 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 56459565 Common nadC Nicotinate-nucleotide pyrophosphorylase IL0454 205 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 56460182 Common gltD glutamate synthase subunit beta IL1074 200 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 56459801 Common - Transcriptional regulator, TetR family IL0692 96 COG1309 AcrR, Transcriptional regulator Transcription 56459383 Common - Na+-dependent transporter of the SNF family IL0272 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 56461191 Nonpathogen - Predicted membrane protein IL2091 1 None None None 56459605 Common - hypothetical protein IL0494 37 COG1315 COG1315, Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain DNA replication, recombination, and repair 56460790 Common dnaE DNA polymerase III subunit alpha IL1689 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 56460020 Nonpathogen - hypothetical protein IL0912 2 None None None 56459214 Common pncB nicotinate phosphoribosyltransferase IL0103 131 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 56461005 Common rplX 50S ribosomal protein L24 IL1905 212 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 56459693 Common nhaC Na+/H+ antiporter IL0584 75 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 56461318 Common - Transcription regulator IL2218 131 COG1678 COG1678, Putative transcriptional regulator Transcription 56460510 Common ribC riboflavin synthase subunit alpha IL1402 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 56460597 Common - hypothetical protein IL1489 3 None None None 56459529 Common - Cytochrome c1 IL0418 75 COG2857 CYT1, Cytochrome c1 Energy production and conversion 56460901 Common motY Sodium-type flagellar protein motY precursor IL1801 114 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 56459350 Common dfp Phosphopantothenoylcysteine synthetase/decarboxylase IL0239 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 56461568 Nonpathogen - hypothetical protein IL2468 1 None None None 56461247 Common secF Preprotein translocase subunit SecF IL2147 208 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 56460913 Common - hypothetical protein IL1813 2 None None None 56459416 Common - MutT/nudix family protein IL0305 33 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 56459988 Common - Signaling protein with a ligand binding sensor domain, GGDEF and EAL domains IL0880 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 56459825 Common ggt_1 Gamma-glutamyltranspeptidase IL0716 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 56460973 Common - putative ABC transporter ATP-binding protein IL1873 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 56460157 Common nqrB Na(+)-translocating NADH-quinone reductase subunit B IL1049 76 COG1805 NqrB, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB Energy production and conversion 56460146 Common sohB predicted inner membrane peptidase IL1038 189 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 56459838 Common pspC Putative stress-responsive transcriptional regulator IL0729 40 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 56461731 Common mioC Flavodoxin IL2631 69 COG0716 FldA, Flavodoxins Energy production and conversion 56461678 Common - Glutamate synthase, putative IL2578 202 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 56460291 Common rluD 23S rRNA pseudouridine synthase D IL1183 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 56459434 Common nudE ADP-ribose diphosphatase NudE IL0323 143 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 56459791 Nonpathogen - hypothetical protein IL0682 1 None None None 56460632 Common asnB Asparagine synthase (glutamine-hydrolyzing) IL1526 186 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 56459370 Common cyoB Cytochrome c oxidase subunit I IL0259 175 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 56461142 Common - rRNA methyltransferase, TrmH family IL2042 156 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 56459331 Nonpathogen - hypothetical protein IL0220 1 None None None 56461522 Common - Alpha/beta superfamily hydrolase IL2422 24 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 56459431 Common ompR osmolarity response regulator IL0320 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 56460501 Common himA Bacterial nucleoid DNA-binding protein, IHF alpha subunit IL1393 210 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 56461091 Common deaD ATP-dependent RNA helicase IL1991 239 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 56461162 Common - Signaling protein with a HAMP, PAS and Histidine kinase domain IL2062 211 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 56460187 Common pal Peptidoglycan-associated lipoprotein IL1079 151 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 56460023 Common - beta-hexosaminidase IL0915 176 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 56460607 Common sucC succinyl-CoA synthetase subunit beta IL1501 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 56460576 Common - ATPase involved in DNA replication initiation IL1468 184 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 56461328 Common - Predicted phosphotransferase related to Ser/Thr protein kinase IL2228 90 COG3178 COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases General function prediction only 56461016 Common rpmC Ribosomal protein L29 IL1916 101 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 56460178 Nonpathogen - hypothetical protein IL1070 10 None None None 56460628 Common - Transcriptional regulator, MarR family IL1522 119 COG1846 MarR, Transcriptional regulators Transcription 56461508 Common - Permease of the major facilitator superfamily IL2408 26 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 56460760 Common kdpD K+ sensor histidine kinase IL1659 216 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 56461284 Common - Possible biopolymer transport protein, ExbB family IL2184 4 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 56459946 Common - Predicted membrane-associated Zn-dependent protease IL0838 216 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 56459325 Nonpathogen - hypothetical protein IL0214 1 None None None 56459180 Common - Outer membrane protein IL0069 87 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 56461676 Common - Peroxiredoxin, AhpC/Tsa family IL2576 208 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 56459607 Common - Metal-dependent hydrolase of the aminoacylase-2/carboxypeptidase-Z family IL0496 56 COG3608 COG3608, Predicted deacylase General function prediction only 56461410 Common - WD40 repeats containg secreted protein IL2310 40 COG2319 COG2319, FOG: WD40 repeat General function prediction only 56459533 Common - Phosphoheptose isomerase IL0422 63 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 56460401 Nonpathogen - Zn-ribbon protein IL1293 1 None None None 56460045 Common fumC fumarate hydratase IL0937 232 COG0114 FumC, Fumarase Energy production and conversion 56460887 Nonpathogen - hypothetical protein IL1787 1 None None None 56459817 Common - hypothetical protein IL0708 94 COG0391 COG0391, Uncharacterized conserved protein Function unknown 56460008 Common - hypothetical protein IL0900 4 None None None 56460687 Common - hypothetical protein IL1583 13 None None None 56460286 Common - Na+/solute symporter, Ssf family IL1178 163 COG4147 DhlC, Predicted symporter General function prediction only 56461704 Nonpathogen - hypothetical protein IL2604 1 None None None 56461717 Common glmU N-acetylglucosamine-1-phosphate uridyltransferase IL2617 237 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 56461540 Common - hypothetical protein IL2440 7 None None None 56460367 Common - Predicted glycosyltransferase IL1259 7 COG5581 COG5581, Predicted glycosyltransferase Cell envelope biogenesis, outer membrane 56460900 Common nth Endonuclease III IL1800 240 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 56459836 Common - hypothetical protein IL0727 41 COG3768 COG3768, Predicted membrane protein Function unknown 56459984 Common - Enoyl-CoA hydratase/isomerase family protein IL0876 173 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 56461429 Common gor glutathione reductase IL2329 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 56460630 Common - hypothetical protein IL1524 12 None None None 56459505 Common ptsN Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) IL0394 131 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 56459617 Common lgt Prolipoprotein diacylglyceryl transferase IL0506 205 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 56459174 Common - Divalent cation exporter protein IL0063 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 56461180 Nonpathogen - hypothetical protein IL2080 1 None None None 56460238 Common mviN MviN-like membrane protein IL1130 189 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 56459202 Common - Long-chain acyl-CoA synthetase IL0091 207 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 56460209 Common ccmF Cytochrome c biogenesis factor IL1101 141 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 56461187 Common - hypothetical protein IL2087 7 None None None 56461561 Common priA Primosomal protein A (replication factor Y), superfamily II helicase IL2461 213 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 161761288 Common udk uridine kinase IL1536 84 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 56461102 Common bvg Predicted transcriptional regulator IL2002 112 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 56460433 Common bioA Adenosylmethionine-8-amino-7-oxononanoate aminotransferase IL1325 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 56459317 Common - Intracellular signaling protein (GAF,GGDEF,EAL domains) IL0206 180 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 56460151 Common - Uncharacterized conserved membrane or secreted protein IL1043 26 COG2991 COG2991, Uncharacterized protein conserved in bacteria Function unknown 56460845 Common - Predicted transcriptional regulator containing the HTH domain IL1744 152 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 56460191 Common - TonB system biopolymer transport component IL1083 147 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 56459576 Common - Transcriptional regulator, LysR family IL0465 135 COG0583 LysR, Transcriptional regulator Transcription 56460324 Common - Uncharacterized conserved secreted protein with internal repeats IL1216 13 COG1422 COG1422, Predicted membrane protein Function unknown 56461582 Common - Sugar efflux permease, MFS-like IL2482 61 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 56460343 Common sufI Multicopper oxidase IL1235 123 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 56461079 Common - Xanthosine triphosphate pyrophosphatase related enzyme IL1979 236 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 56459460 Common fusA elongation factor G IL0349 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 56461242 Common ribH Riboflavin synthase beta chain IL2142 230 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 56460789 Common accA AcetylCoA carboxylase, carboxytransferase component, alpha subunit IL1688 192 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 56461652 Common - Predicted phosphohydrolase, HAD superfamily IL2552 62 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 56460355 Common - Uncharacterized conserved secreted protein with internal repeats IL1247 24 None None None 56460798 Common gloB Probable hydroxyacylglutathione hydrolase GloB IL1697 209 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 56461549 Common - Acetyltransferase, GNAT family fused to PaaI related uncharacterized conserved domain IL2449 48 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 56460513 Common - Outer membrane protein, porin family IL1405 5 None None None 56460869 Common tesA Acyl-CoA thioesterase I IL1768 109 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 56459123 Common fadB multifunctional fatty acid oxidation complex subunit alpha IL0011 180 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 56460783 Common - hypothetical protein IL1682 25 COG3821 COG3821, Predicted membrane protein Function unknown 56459677 Common - Fusion of WbfC- and WbfB-like uncharacterized domains involved in polysaccharide synthesis IL0568 21 None None None 56461234 Common motB flagellar motor protein MotB IL2134 93 COG1360 MotB, Flagellar motor protein Cell motility and secretion 56460002 Common - hypothetical protein IL0894 42 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 56460561 Common crr PTS system, glucose-specific IIA component IL1453 12 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 56461646 Nonpathogen - hypothetical protein IL2546 1 None None None 56459848 Common ggt_2 Gamma-glutamyltranspeptidase IL0739 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 56460302 Common fliL flagellar basal body-associated protein FliL IL1194 14 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 56459682 Common cysQ 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase IL0573 187 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 56461220 Common - Signal transduction histidine kinase IL2120 225 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 56460690 Common - Zn-dependent hydrolase, glyoxylase family IL1586 41 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 56460820 Common - Cytochrome b IL1719 45 COG3658 COG3658, Cytochrome b Energy production and conversion 56461558 Common hslV ATP-dependent protease peptidase subunit IL2458 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 56459668 Common galE UDP-glucose 4-epimerase IL0559 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 56460252 Common flgE flagellar hook protein FlgE IL1144 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 56461201 Common - Amidohydrolase family enzyme IL2101 36 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 56461169 Common - Thioredoxin related protein IL2069 71 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 56461289 Nonpathogen - hypothetical protein IL2189 1 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 56459163 Common tra5_2 Transposase Tra5 related protein IL0051 49 None None None 56461098 Common - Prolyl endopeptidase IL1998 117 COG1505 COG1505, Serine proteases of the peptidase family S9A Amino acid transport and metabolism 56459258 Common - Intracellular signaling protein (EAL-mHD-GYP) IL0147 45 COG3434 COG3434, Predicted signal transduction protein containing EAL and modified HD-GYP domains Signal transduction mechanisms 56459507 Common rpoN RNA polymerase factor sigma-54 IL0396 145 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 56459543 Common murF UDP-N-acetylmuramyl pentapeptide synthase IL0432 209 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 56459824 Common - hypothetical protein IL0715 4 None None None 56459587 Common rpmA 50S ribosomal protein L27 IL0476 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 56460031 Common - Response regulator containing a CheY-like receiver domain and an HD-GYP domain IL0923 31 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 56461346 Common mrcB Peptidoglycan synthetase IL2246 202 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 56460032 Common hemK HemK IL0924 226 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 56461081 Common - Predicted methyltransferase IL1981 178 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 56460640 Common tesB Acyl-CoA thioesterase II IL1534 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 56461076 Common - hypothetical protein IL1976 123 COG0762 COG0762, Predicted integral membrane protein Function unknown 56460543 Common - Predicted metal-dependent hydrolase IL1435 143 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 56460709 Common - Conserved protein containing a Zn-ribbon-like motif IL1605 25 COG5516 COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding General function prediction only 56460096 Common nadF NAD kinase IL0988 237 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 56460213 Common ccmB ABC-type transport system involved in cytochrome c biogenesis, permease component IL1105 80 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 56460038 Common rplY Ribosomal protein L25 IL0930 189 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 56460361 Common - hypothetical protein IL1253 11 None None None 56459580 Common - hypothetical protein IL0469 44 COG4805 COG4805, Uncharacterized protein conserved in bacteria Function unknown 56460878 Common - Aspartate racemase IL1778 86 COG1794 RacX, Aspartate racemase Cell envelope biogenesis, outer membrane 56459375 Common ubiA 4-hydroxybenzoate polyprenyltransferase IL0264 176 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 56460746 Common merP Periplasmic mercuric ion binding protein, MerP IL1645 70 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 56459645 Common - Predicted C-terminal GTPase domain fused to uncharaterized conserved domain IL0536 28 COG4735 COG4735, Uncharacterized protein conserved in bacteria Function unknown 56460275 Common - hypothetical protein IL1167 22 None None None 56461712 Common tnsB Transposon Tn7 transposition protein tnsB IL2612 51 None None None 56459917 Common era GTPase Era IL0809 239 COG1159 Era, GTPase General function prediction only 56460019 Nonpathogen - RelE/ParE family protein IL0911 5 COG3668 ParE, Plasmid stabilization system protein General function prediction only 56461500 Common capB Capsular polyglutamate biosynthesis secreted protein CapB, ATP-dependent mur ligase family IL2400 13 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 56459829 Common - 2-keto-4-pentenoate hydratase IL0720 66 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 56459741 Common - Co/Zn/Cd efflux system component IL0632 89 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 56460907 Common - Alpha/beta superfamily hydrolase IL1807 155 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 56460010 Common tadB Flp pilus assembly protein TadB IL0902 74 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 56460921 Common fadR_2 fatty acid metabolism regulator IL1821 77 COG2186 FadR, Transcriptional regulators Transcription 56460263 Common - Sterol desaturase-related protein IL1155 71 COG3000 ERG3, Sterol desaturase Lipid metabolism 56461498 Common - Phosphodiesterase-nucleotide pyrophosphatase related protein, AP superfamily IL2398 36 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 56459902 Nonpathogen - hypothetical protein IL0794 9 None None None 56459236 Common - beta-ketoacyl synthase N-terminal domain-like protein IL0125 32 None None None 56459345 Common - Rhodanese-related sulfurtransferase IL0234 150 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 56459964 Common - Aminopeptidase N family protein, contains PDZ domain IL0856 56 COG3975 COG3975, Predicted protease with the C-terminal PDZ domain General function prediction only 56459368 Common cyoC Cytochrome c oxidase subunit III IL0257 154 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 56460158 Common nqrA Na(+)-translocating NADH-quinone reductase subunit A IL1050 44 COG1726 NqrA, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA Energy production and conversion 56459600 Common - hypothetical protein IL0489 77 COG1469 COG1469, Uncharacterized conserved protein Function unknown 56461350 Common dksA DnaK IL2250 147 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 56460369 Common - Response regulator of the LytR/AlgR family IL1261 222 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 56461185 Nonpathogen - Alpha-hemolysin family protein IL2085 1 None None None 56461363 Common ppa inorganic pyrophosphatase IL2263 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 56461337 Common - Peptidase, M23/M37 family IL2237 189 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 56461057 Common tolC outer membrane channel protein IL1957 148 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 56459907 Common - ZIP family metal transporter IL0799 116 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 56459225 Common hmuU ABC-type hemin transport system, pemease component IL0114 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 56459983 Common - 3-methylcrotonyl CoA carboxylase, beta subunit IL0875 144 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 56459295 Common narX Nitrate/nitrite sensor histidine kinase IL0184 148 COG3850 NarQ, Signal transduction histidine kinase, nitrate/nitrite-specific Signal transduction mechanisms 56459632 Common ung uracil-DNA glycosylase IL0522 128 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 56459996 Common fdx Ferredoxin IL0888 90 COG0633 Fdx, Ferredoxin Energy production and conversion 56459953 Common rpsB 30S ribosomal protein S2 IL0845 221 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 56459229 Common - Calcineurin-like phosphoesterase IL0118 6 COG1409 Icc, Predicted phosphohydrolases General function prediction only 56461267 Common - Predicted permease PerM family IL2167 132 COG0628 PerM, Predicted permease General function prediction only 56460532 Common - Conserved protein related to proline racemase IL1424 55 COG2828 COG2828, Uncharacterized protein conserved in bacteria Function unknown 56460971 Common - hypothetical protein IL1871 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 56461359 Common - ABC-type multidrug transport system, ATPase component IL2259 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 56460080 Common tpiA Triosephosphate isomerase IL0972 219 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 56461307 Common pitA Phosphate permease IL2207 178 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 56461111 Common phoA Alkaline phosphatase IL2011 84 COG1785 PhoA, Alkaline phosphatase Inorganic ion transport and metabolism 56459703 Common - Possible cAMP phosphodiesterase, metallo-beta-lactamase superfamily IL0594 50 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 56459392 Common tex Transcriptional accessory protein IL0281 216 COG2183 Tex, Transcriptional accessory protein Transcription 56459786 Common - nucleoid-associated protein NdpA IL0677 31 COG3081 COG3081, Nucleoid-associated protein General function prediction only 56460304 Common fliJ Flagellar biosynthesis chaperone IL1196 26 COG2882 FliJ, Flagellar biosynthesis chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 56459384 Common pckA phosphoenolpyruvate carboxykinase IL0273 95 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 56461109 Common ppx Exopolyphosphatase IL2009 182 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 56461031 Common - hypothetical protein IL1931 7 None None None 56460959 Common - TonB system biopolymer transport component IL1859 18 None None None 56459338 Common ftsE FtsE IL0227 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 56460486 Nonpathogen - hypothetical protein IL1378 2 None None None 56459863 Common - Predicted permease IL0754 55 COG0730 COG0730, Predicted permeases General function prediction only 56460407 Nonpathogen ccoQ Cytochrome c oxidase, cbb3-type, CcoQ subunit IL1299 1 COG4736 CcoQ, Cbb3-type cytochrome oxidase, subunit 3 Posttranslational modification, protein turnover, chaperones 56461634 Common - Transporter, LysE family IL2534 86 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 56461055 Common - hypothetical protein IL1955 25 COG3151 COG3151, Uncharacterized protein conserved in bacteria Function unknown 56460947 Common recR Recombinational DNA repair protein IL1847 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 56460390 Common - N6-adenine-specific DNA methylase IL1282 147 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 56459520 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase IL0409 223 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 56460472 Common nrdB ribonucleotide-diphosphate reductase subunit beta IL1364 154 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 56460114 Common tig trigger factor IL1006 216 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 56459910 Common - hypothetical protein IL0802 17 None None None 56460530 Common - hypothetical protein IL1422 9 None None None 56461386 Common accC acetyl-CoA carboxylase biotin carboxylase subunit IL2286 232 COG0439 AccC, Biotin carboxylase Lipid metabolism 56461062 Nonpathogen - Predicted membrane protein IL1962 1 None None None 56459748 Common alpA prophage CP4-57 regulatory protein-like protein IL0639 39 COG3311 AlpA, Predicted transcriptional regulator Transcription 56460454 Common maf_2 Nucleotide-binding protein implicated in inhibition of septum formation IL1346 191 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 56461451 Common - Rhodanese-like sulfurtransferase IL2351 116 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 56459146 Common - Amidase related to nicotinamidase IL0034 90 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 56460940 Common hisF imidazole glycerol phosphate synthase subunit HisF IL1840 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 56459689 Nonpathogen - Uncharacterized conserved secreted protein, distantly related to OmpA family IL0580 1 None None None 56459896 Common - DSBH domain containing protein IL0788 39 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 56460602 Nonpathogen - hypothetical protein IL1496 2 None None None 56460245 Common flgL Flagellin IL1137 96 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 56460681 Common hadL L-2-haloalkanoic acid dehalogenase, HAD superfamily IL1575 80 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 56460480 Common - Predicted exporter, RND superfamily IL1372 54 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 56460987 Common - Predicted outer membrane protein IL1887 127 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 56460863 Common - Secreted Zn-dependent hydrolase of beta-lactamase superfamily IL1762 102 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 56460814 Common rsbU Response regulator of sigma subunit, serine phosphatase (CheY-RsbU) IL1713 187 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 56459656 Common - Acetyltransferase, isoleucine patch superfamily IL0547 153 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 56461029 Common - Transcriptional regulator of Zn2+ uptake IL1929 151 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 56461662 Common yceI hypothetical protein IL2562 115 COG2353 COG2353, Uncharacterized conserved protein Function unknown 56460205 Common vacJ Surface lipoprotein IL1097 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 56461271 Common - Il-IS_1, transposase IL2170.1 105 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 56461019 Common rplV 50S ribosomal protein L22 IL1919 227 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 56459121 Common sirA Predicted redox protein, regulator of disulfide bond formation IL0009 97 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 56459517 Common - ABC-type transport system involved in resistance to organic solvents, auxiliary component IL0406 71 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 56459591 Common - Probable secreted peptidase of alpha/beta hydrolase superfamily IL0480 68 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 56459711 Common - RND family efflux transporter IL0602 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 56461692 Common - Uncharacterized conserved membrane protein, probable transporter IL2592 6 None None None 56460579 Common pgm phosphoglucomutase IL1471 222 COG0033 Pgm, Phosphoglucomutase Carbohydrate transport and metabolism 56460250 Common flgG flagellar basal body rod protein FlgG IL1142 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 56460055 Common leuS leucyl-tRNA synthetase IL0947 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 56459119 Common tag 3-methyladenine DNA glycosylase IL0007 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 56459774 Common - recombination factor protein RarA IL0665 233 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 56459495 Common maf_1 Nucleotide-binding protein implicated in inhibition of septum formation IL0384 194 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 56459764 Common alkA 3-methyladenine DNA glycosylase IL0655 77 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 56459527 Common - Ubiquinol-cytochrome C reductase iron-sulfur subunit IL0416 97 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 56460651 Common - Secreted protein, containing thioredoxin-like domain IL1545 3 None None None 56461348 Common pepB aminopeptidase B IL2248 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 56460848 Common - Predicted metal-dependent phosphoesterase, PHP family IL1747 130 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 56461529 Common - Uncharacterized protein, containing periplasmic binding domain IL2429 5 None None None 56460508 Common - Predicted permease, DMT superfamily IL1400 27 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 56461003 Common rpsN Ribosomal protein S14 IL1903 211 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 56461444 Common - Intracellular signaling protein (GAF,PAS,GGDEF,EAL domains) IL2344 188 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 56461374 Common - MerC-like membrane protein IL2274 4 None None None 56459843 Common dppB ABC-type dipeptide transport systems, permease component IL0734 218 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 56461681 Common - Predicted intracellular protease/amidase, ThiJ/PfpL family IL2581 139 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 56459621 Common - Chemotaxis response regulator IL0510 171 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 56460224 Common cheY Chemotaxis protein CheY IL1116 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 56460715 Common - Transcriptional regulator, LysR family IL1611 159 COG0583 LysR, Transcriptional regulator Transcription 56460827 Common rpsP Ribosomal protein S16 IL1726 211 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 56460363 Common - Transporter, LysE family IL1255 97 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 56460855 Common trpC bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase IL1754 220 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 56460164 Common pqiB Paraquat-inducible protein B, secreted IL1056 64 COG3008 PqiB, Paraquat-inducible protein B General function prediction only 56461702 Common - Secreted metallopeptidase, family M23/M37 IL2602 118 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 56459126 Common - hypothetical protein IL0014 133 COG1739 COG1739, Uncharacterized conserved protein Function unknown 56460266 Common - ABC-type uncharacterized transport system, permease component IL1158 28 COG4135 COG4135, ABC-type uncharacterized transport system, permease component General function prediction only 56459292 Common - Collagenase family protease IL0181 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 56460314 Common - Response regulator, LuxR family (CheY, HTH domains) IL1206 179 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 56459995 Common gpt xanthine-guanine phosphoribosyltransferase IL0887 119 COG2236 COG2236, Predicted phosphoribosyltransferases General function prediction only 56459738 Common rnk Transcription elongation factor family protein IL0629 65 COG0782 GreA, Transcription elongation factor Transcription 56460803 Common smc Chromosome segregation ATPase, sms IL1702 183 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 56461414 Common - OsmC-like predicted redox protein IL2314 86 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 56461391 Common - Predicted O-methyltransferase IL2291 21 COG4798 COG4798, Predicted methyltransferase General function prediction only 56461472 Common - hypothetical protein IL2372 43 COG3165 COG3165, Uncharacterized protein conserved in bacteria Function unknown 56459407 Common - Response regulator of the LytR/AlgR family IL0296 195 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 56461458 Common - Outer membrane protein IL2358 86 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 56460932 Common dinG ATP-dependent DNA helicase IL1832 152 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 56461709 Common tnsE Transposon Tn7 transposition transposition regulatory protein tnsE IL2609 7 None None None 56460599 Common - ATP-dependent RNA helicase IL1491 231 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 56460069 Common - hypothetical protein IL0961 27 COG3686 COG3686, Predicted membrane protein Function unknown 56459550 Common ftsQ Cell division septal protein IL0439 80 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 56459950 Common frr Ribosome recycling factor IL0842 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 56459280 Common - Transcriptional regulator, ArsR family IL0169 149 COG0640 ArsR, Predicted transcriptional regulators Transcription 56461518 Common - Transporter, LysE family IL2418 83 COG1279 COG1279, Lysine efflux permease General function prediction only 56460494 Common - Short chain dehydrogenase family protein IL1386 235 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 56460838 Common csrA Carbon storage regulatory protein IL1737 81 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 56460425 Common - hypothetical protein IL1317 113 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 56460676 Common - Uncharacterized secreted protein IL1570 34 COG2849 COG2849, Uncharacterized protein conserved in bacteria Function unknown 56461436 Common ptr Secreted Zn-dependent peptidase, insulinase family IL2336 188 COG1025 Ptr, Secreted/periplasmic Zn-dependent peptidases, insulinase-like Posttranslational modification, protein turnover, chaperones 56460515 Common gabD Succinate-semialdehyde dehydrogenase IL1407 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 56461216 Common - Biopolymer transport protein IL2116 121 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 56459486 Common mshC Type II secretory pathway component IL0375 5 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 56459971 Common - hypothetical protein IL0863 76 COG2363 COG2363, Uncharacterized small membrane protein Function unknown 56460345 Common - Secreted metal-binding protein IL1237 64 COG3019 COG3019, Predicted metal-binding protein General function prediction only 56460386 Common - hypothetical protein IL1278 6 None None None 56460736 Common - Lipoprotein signal peptidase IL1635 199 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 56461422 Common - Intracellular signaling protein (2 PAS, GGDEF,EAL domains) IL2322 189 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 56460127 Common asd Aspartate-semialdehyde dehydrogenase IL1019 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 56459876 Common thiF Thiamine biosynthesis protein ThiF IL0767 223 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 56460697 Common fecR Iron-dicitrate sensor, membrane component IL1593 48 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 56460062 Common mrdB Bacterial cell division membrane protein IL0954 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 56459137 Common polA DNA polymerase I IL0025 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 56460889 Common uvrB excinuclease ABC subunit B IL1789 229 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 56460587 Common - Allophanate hydrolase subunit 2 IL1479 115 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 56459736 Common - Transcriptional regulator, LysR family IL0627 190 COG0583 LysR, Transcriptional regulator Transcription 56459492 Common mreB Actin-like ATPase IL0381 235 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 56459598 Common cbiB Cobalamin biosynthesis membrane protein IL0487 56 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 56460770 Common - 2OG-Fe(II) oxygenase superfamily protein IL1669 54 COG3491 PcbC, Isopenicillin N synthase and related dioxygenases General function prediction only 56461626 Common - Predicted hydrolase of the alpha/beta superfamily IL2526 31 COG2819 COG2819, Predicted hydrolase of the alpha/beta superfamily General function prediction only 56461223 Common - Predicted Zn-dependent hydrolase IL2123 13 None None None 56459638 Common - Predicted ATPase, AAA+ superfamily IL0529 58 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 56460410 Common - Cation transport ATPase IL1302 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 56459248 Common - RND superfamily exporter IL0137 25 COG4258 COG4258, Predicted exporter General function prediction only 56460594 Common - Predicted aminoglycoside phosphotransferase IL1486 59 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 56459414 Common - Transcriptional regulator, PaiB homolog IL0303 60 COG2808 PaiB, Transcriptional regulator Transcription 56459815 Common - hypothetical protein IL0706 80 COG1430 COG1430, Uncharacterized conserved protein Function unknown 56460843 Common - Peptidyl-arginine deiminase related enzyme IL1742 87 COG2957 COG2957, Peptidylarginine deiminase and related enzymes Amino acid transport and metabolism 56459961 Common - Predicted acetyltransferase, GNAT family IL0853 7 COG0456 RimI, Acetyltransferases General function prediction only 56459286 Common - Methyl-accepting chemotaxis protein IL0175 147 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 56461258 Common - hypothetical protein IL2158 6 None None None 56461299 Common - Predicted metal-dependent hydrolase IL2199 39 COG3618 COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 56460469 Common ubiG 3-demethylubiquinone-9 3-methyltransferase IL1361 194 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 56459469 Common - Multidrug resistance efflux pump, HlyD family IL0358 141 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 56460692 Common - Predicted membrane protein IL1588 3 COG5129 MAK16, Nuclear protein with HMG-like acidic region General function prediction only 56460537 Common - hypothetical protein IL1429 102 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 56460333 Nonpathogen - Uncharacterized conserved protein, IL-2 family IL1225 1 None None None 56460637 Common - Short chain dehydrogenase/reductase family protein IL1531 232 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 56461042 Common - RRNA methylase, SpoU family IL1942 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 56460199 Common - SAM-dependent methyltransferase IL1091 52 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 56459853 Common mutS DNA mismatch repair protein IL0744 202 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 56459756 Common - hypothetical protein IL0647 3 None None None 56460445 Common - Aminodeoxychorismate lyase related protein IL1337 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 56460831 Common - hypothetical protein IL1730 38 COG4764 COG4764, Uncharacterized protein conserved in bacteria Function unknown 56461460 Common ubiD 3-polyprenyl-4-hydroxybenzoate decarboxylase IL2360 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 56460298 Common fliP flagellar biosynthesis protein FliP IL1190 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 56459630 Common siaC Sialic acid synthase IL0519 78 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 56459154 Common cydB Cytochrome bd-type quinol oxidase, subunit 2 IL0042 150 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 56461128 Common - Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit IL2028 111 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 56460524 Common - Predicted carboxypeptidase, Zn-dependent IL1416 34 COG2866 COG2866, Predicted carboxypeptidase Amino acid transport and metabolism 56459726 Common - Zn-dependent hydrolase, glyoxylase family IL0617 118 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 56461555 Common menG ribonuclease activity regulator protein RraA IL2455 70 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 56459182 Common - Transcriptional regulator, TetR family IL0071 101 COG1309 AcrR, Transcriptional regulator Transcription 56460647 Common - Predicted exonuclease of the beta-lactamase fold IL1541 125 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 56460189 Common tolA TolA-like protein IL1081 15 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 56460621 Common - hypothetical protein IL1515 44 COG3216 COG3216, Uncharacterized protein conserved in bacteria Function unknown 56459141 Common - hypothetical protein IL0029 23 COG3078 COG3078, Uncharacterized protein conserved in bacteria Function unknown 56461720 Common atpG F0F1-type ATP synthase, gamma subunit IL2620 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 56459458 Common rpsL 30S ribosomal protein S12 IL0347 240 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 56461164 Common - Methyl-accepting chemotaxis protein (2 PAS,MCP domains) IL2064 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 56459695 Common - Metal-dependent hydrolase of the aminoacylase-2/carboxypeptidase-Z family IL0586 169 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 56461360 Common ubiX aromatic acid decarboxylase IL2260 152 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 56460997 Common rplO 50S ribosomal protein L15 IL1897 214 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 56461291 Common - Predicted permease, DMT superfamily IL2191 88 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 56461479 Common - Endoribonuclease L-PSP family protein IL2379 184 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 56460029 Common - hypothetical protein IL0921 26 COG5505 COG5505, Predicted integral membrane protein Function unknown 56461412 Common prkB Phosphoribulokinase IL2312 51 COG3954 PrkB, Phosphoribulokinase Energy production and conversion 56459510 Common - hypothetical protein IL0399 28 COG3117 COG3117, Uncharacterized protein conserved in bacteria Function unknown 56460460 Common - hypothetical protein IL1352 66 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 56459312 Common - K+ uptake system component IL0201 110 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 56459211 Common - Signaling protein with membrane-bound sensor domain and GGDEF domain IL0100 87 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 56461640 Nonpathogen - hypothetical protein IL2540 4 None None None 56460600 Common - Alpha/beta superfamily hydrolase IL1494 7 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 56459956 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase IL0848 141 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 56461070 Common - Probable O-sialoglycoprotein endopeptidase IL1970 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 56461570 Nonpathogen - Predicted secreted protein IL2470 1 None None None 56461596 Common - Predicted protein-S-isoprenylcysteine methyltransferase IL2496 51 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 56461432 Common - hypothetical protein IL2332 63 COG1742 COG1742, Uncharacterized conserved protein Function unknown 56461706 Nonpathogen - hypothetical protein IL2606 1 None None None 56459220 Common - Outer membrane protein IL0109 81 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 56460043 Common - Signaling protein with a sensor domain, HAMP, GGDEF and EAL domains IL0935 174 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 56460511 Common - hypothetical protein IL1403 9 None None None 56459115 Common recF Recombinational DNA repair ATPase IL0003 167 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 56461577 Common - SAM-dependent methyltransferase IL2477 51 None None None 56461232 Common - Uncharacterized conserved membrane protein, VanZ family IL2132 7 COG5652 COG5652, Predicted integral membrane protein Function unknown 56461542 Common - Uncharacterized conserved membrane protein, SapB/MtgC family IL2442 117 COG1285 SapB, Uncharacterized membrane protein Function unknown 56461457 Common - hypothetical protein IL2357 10 COG0011 COG0011, Uncharacterized conserved protein Function unknown 56460329 Common - Nitrogen regulatory protein PII IL1221 22 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 56459675 Nonpathogen - hypothetical protein IL0566 1 None None None 56460086 Nonpathogen - hypothetical protein IL0978 1 None None None 56460281 Common - Outer membrane protein IL1173 111 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 56461636 Nonpathogen - Secreted TPR-repeat containing protein IL2536 7 None None None 56461155 Common - RelE/ParE family protein, cytotoxic translational repressor of toxin-antitoxin stability system IL2055 37 COG3549 HigB, Plasmid maintenance system killer protein General function prediction only 56459144 Common aer Methyl-accepting chemotaxis protein (PAS/PAC and MSP doamins) IL0032 160 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 56461158 Common - ABC-type transport system, ATPase component IL2058 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 56460552 Common - Phospholipase D family protein IL1444 140 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 56459172 Nonpathogen - Outer membrane protein IL0061 2 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 56461147 Common - Protein containing HTH-type DNA-binding domain and DOC/FIC domain involved in death-on-curing system IL2047 64 COG3943 COG3943, Virulence protein General function prediction only 56460794 Common dnaQ DNA polymerase III, epsilon subunit IL1693 190 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 56461531 Common - Cation transporter, CDF family IL2431 196 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 56459615 Common ptsP Intracellular signaling protein (GAF,PtsI domains) IL0504 235 COG3605 PtsP, Signal transduction protein containing GAF and PtsI domains Signal transduction mechanisms 56459125 Common pepQ Proline aminopeptidase P II IL0013 104 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 56459319 Common - hypothetical protein IL0208 27 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 56460605 Common - IS4-like transposase IL1499 27 COG3385 COG3385, FOG: Transposase and inactivated derivatives DNA replication, recombination, and repair 56460382 Common prc carboxy-terminal protease IL1274 183 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 56459187 Common xenA Xenobiotic reductase A IL0076 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 56459394 Common - hypothetical protein IL0283 10 None None None 56459179 Nonpathogen - Membrane associated protein containing Zn-ribbon domain IL0068 1 COG4640 COG4640, Predicted membrane protein Function unknown 56460540 Common - Thioesterase (4HBT) superfamily enzyme IL1432 16 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 56459437 Common - ATPase component of ABC transporters with duplicated ATPase domains IL0326 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 56460503 Common pheS phenylalanyl-tRNA synthetase subunit alpha IL1395 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 56460273 Common - Carboxymuconolactone decarboxylase family enzyme IL1165 55 COG2128 COG2128, Uncharacterized conserved protein Function unknown 56460488 Common - hypothetical protein IL1380 36 None None None 56461679 Common - Glucose dehydrogenase, putative IL2579 126 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 56459323 Common - Thioredoxin related protein IL0212 49 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 56459333 Common tdcB Threonine dehydratase IL0222 189 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 56460309 Common fliE Flagellar hook-basal body protein IL1201 82 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 56459574 Common - Probable Co/Zn/Cd efflux system membrane fusion protein IL0463 136 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 56460025 Common - acyl-CoA dehydrogenase IL0917 143 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 56461506 Common - Predicted Rossmann fold nucleotide-binding protein IL2406 114 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 56460683 Common - hypothetical protein IL1577 63 COG3803 COG3803, Uncharacterized protein conserved in bacteria Function unknown 56459869 Nonpathogen - hypothetical protein IL0760 6 None None None 56460626 Common mfd Transcription-repair coupling factor, superfamily II helicase IL1520 235 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 56459438 Common - Predicted nucleic-acid-binding protein containing a Zn-ribbon domain IL0327 22 COG3529 COG3529, Predicted nucleic-acid-binding protein containing a Zn-ribbon domain General function prediction only 56459975 Common mmsB 3-hydroxyisobutyrate dehydrogenase IL0867 183 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 56461698 Nonpathogen - Predicted secreted protein IL2598 1 None None None 56459805 Nonpathogen - hypothetical protein IL0696 1 COG5487 COG5487, Small integral membrane protein Function unknown 56459353 Common rpmG 50S ribosomal protein L33 IL0242 128 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 56461160 Common - ABC-type transport system, permease component IL2060 12 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 56460762 Common purM phosphoribosylaminoimidazole synthetase IL1661 231 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 56460573 Common - Glutaredoxin family protein IL1465 115 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 56459891 Nonpathogen - hypothetical protein IL0782 1 None None None 56461740 Common rpmH 50S ribosomal protein L34 IL2640 41 None None None 56461140 Common - Cysteine sulfinate desulfinase IL2040 239 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 56461196 Common visC FAD-binding oxidoreductase, UbiH/Coq6 family IL2096 134 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 56460419 Common - hypothetical protein IL1311 41 COG2915 COG2915, Uncharacterized protein involved in purine metabolism General function prediction only 56459427 Nonpathogen - hypothetical protein IL0316 1 None None None 56459661 Common - Acetyltransferase, isoleucine patch superfamily IL0552 182 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 56459649 Common - ABC-type multidrug transport system, ATPase and permease components IL0540 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 56461290 Common - Transcriptional regulator, LysR family IL2190 165 COG0583 LysR, Transcriptional regulator Transcription 56459944 Common hlpA Outer membrane protein IL0836 79 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 56461198 Common pepP Xaa-Pro aminopeptidase IL2098 218 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 56460906 Common - IS4-like transposase IL1806 27 COG3385 COG3385, FOG: Transposase and inactivated derivatives DNA replication, recombination, and repair 56459561 Common pulO Type II pili prepilin peptidase PilD/XcpA IL0450 140 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 56459609 Common - Predicted aspartyl protease IL0498 38 COG4067 COG4067, Uncharacterized protein conserved in archaea Posttranslational modification, protein turnover, chaperones 56460791 Common ndh NADH dehydrogenase, FAD-containing subunit IL1690 207 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 56459305 Common - Heme/copper membrane protein IL0194 60 COG3213 NnrS, Uncharacterized protein involved in response to NO Inorganic ion transport and metabolism 56461113 Common - Homoserine acetyltransferase IL2013 59 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 56460635 Nonpathogen - Predicted membrane protein IL1529 1 None None None 56459562 Common pulF Type II secretory pathway, PulF-like IL0451 148 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 56459366 Common - Uncharacterized conserved secreted or membrane protein IL0255 24 None None None 56459573 Nonpathogen - hypothetical protein IL0462 1 None None None 56461734 Common - Predicted endonuclease containing a URI domain IL2634 93 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 56461616 Common vagC VagC IL2516 23 COG4456 VagC, Virulence-associated protein and related proteins Function unknown 56460557 Common - Alpha/beta superfamily hydrolase IL1449 14 None None None 56461183 Common - Uncharacterized conserved protein HipA IL2083 60 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 56460893 Common - Type II phosphatidic acid phosphatase IL1793 76 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 56459784 Common clpS ATP-dependent Clp protease adaptor protein ClpS IL0675 121 COG2127 COG2127, Uncharacterized conserved protein Function unknown 56461265 Common amtB Ammonia permease IL2165 203 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 56461282 Nonpathogen - Secreted protein, containing von Willebrand factor (vWF) type A domain IL2182 1 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 56461365 Common - ABC-type transport system, permease component IL2265 29 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 56459797 Common - Uncharacterized periplasmic substrate-binding protein IL0688 5 None None None 56459602 Common arcA Response regulator (CheY,wHTH domains) IL0491 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 56459238 Common - Acyl carrier protein IL0127 24 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 56461690 Nonpathogen - hypothetical protein IL2590 1 None None None 56459898 Common gcd Glucose dehydrogenase IL0790 58 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 56459268 Common csgF Curli production assembly/transport component, CsgF IL0157 13 None None None 56459624 Common - SufE-like protein probably involved in Fe-S center assembly IL0513 91 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 56460890 Common - Na+-driven multidrug efflux pump IL1790 181 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 56461527 Common - Il-IS_1, transposase IL2426.1 105 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 56460148 Common - short chain dehydrogenase IL1040 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 56459900 Common - Acetoin(diacetyl) reductase IL0792 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 56460409 Common - hypothetical protein IL1301 23 COG3198 COG3198, Uncharacterized protein conserved in bacteria Function unknown 56460658 Nonpathogen - hypothetical protein IL1552 1 None None None 56459716 Common aceK bifunctional isocitrate dehydrogenase kinase/phosphatase protein IL0607 29 COG4579 COG4579, Isocitrate dehydrogenase kinase/phosphatase Signal transduction mechanisms 56459697 Common - Il-IS_1, transposase IL0587.1 105 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 56459931 Common prfB Protein chain release factor B, RF-2 IL0823 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 56459981 Common soxR_3 Transcriptional regulator, MerR family IL0873 62 COG0789 SoxR, Predicted transcriptional regulators Transcription 56459396 Common - Antitoxin of toxin-antitoxin stability system, StbD family IL0285 49 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 56459297 Common - Nitric oxide reductase large subunit IL0186 74 COG3256 NorB, Nitric oxide reductase large subunit Inorganic ion transport and metabolism 56460141 Common cysS cysteinyl-tRNA synthetase IL1033 242 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 56461014 Common - IS4-like transposase IL1914 27 COG3385 COG3385, FOG: Transposase and inactivated derivatives DNA replication, recombination, and repair 56459152 Common dadX Alanine racemase IL0040 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 56459382 Common coaD phosphopantetheine adenylyltransferase IL0271 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 56459933 Common dsbC Protein-disulfide isomerase IL0825 64 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 56460331 Common - Membrane-fusion protein, RND-like efflux system component IL1223 170 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 56461538 Common typA GTP-binding regulator BipA/TypA IL2438 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 56460171 Common prpE Propionyl-CoA synthetase IL1063 218 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 56461604 Common - Possible streptogramin lyase, gluconolactonase family IL2504 22 COG4257 Vgb, Streptogramin lyase Defense mechanisms 56461309 Common - Methyl-accepting chemotaxis protein (contains HAMP domain) IL2209 136 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 56459276 Common - Outer membrane protein OmpW, putative IL0165 69 COG3047 OmpW, Outer membrane protein W Cell envelope biogenesis, outer membrane 56461033 Common dnaB Replicative DNA helicase IL1933 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 56459966 Common - Protein containing a predicted nucleotide-binding domain of Rossmann fold IL0858 56 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 56460700 Common - Outer membrane protein IL1596 44 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 56461654 Common - Uncharacterized conserved protein, YigA-like IL2554 33 COG3159 COG3159, Uncharacterized protein conserved in bacteria Function unknown 56459855 Common nlpD Lipoprotein NlpD IL0746 185 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 56460550 Common - Zn-dependent hydrolase, glyoxylase family IL1442 209 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 56461631 Common recB ATP-dependent exoDNAse (exonuclease V) beta subunit IL2531 220 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 56460721 Common - hypothetical protein IL1617 30 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 56461674 Common - allantoate amidohydrolase IL2574 84 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 56459509 Common - hypothetical protein IL0398 44 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 56460876 Common - Methyl-accepting chemotaxis protein (CHASE3,HAMP,MCP domains) IL1776 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 56460785 Common - Membrane-fusion protein IL1684 145 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 56459826 Common - Predicted membrane serine peptidase, rhomboid homolog IL0717 14 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 56460596 Nonpathogen - Predicted membrane protein IL1488 1 None None None 56460300 Common fliN flagellar motor switch protein IL1192 123 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 56460211 Common ccmD Heme exporter protein D IL1103 6 COG3114 CcmD, Heme exporter protein D Intracellular trafficking and secretion 56461083 Common mutY A/G-specific DNA glycosylase IL1983 231 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 56460004 Common - hypothetical protein IL0896 65 COG2914 COG2914, Uncharacterized protein conserved in bacteria Function unknown 56461648 Common - hypothetical protein IL2548 65 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 56460679 Common - Uncharacterized protein involved in benzoate metabolism IL1573 59 COG3135 BenE, Uncharacterized protein involved in benzoate metabolism Secondary metabolites biosynthesis, transport, and catabolism 56461300 Common rpoD DNA-directed RNA polymerase sigma 70 subunit IL2200 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 56459923 Nonpathogen rseA Negative regulator of sigma E activity IL0815 1 COG3073 RseA, Negative regulator of sigma E activity Signal transduction mechanisms 56460919 Common - N-terminal winged-HTH domain fused to TolB-like domain IL1819 54 COG3710 CadC, DNA-binding winged-HTH domains Transcription 56460707 Common - Predicted transcriptional regulator, rrf2 family IL1603 61 COG1959 COG1959, Predicted transcriptional regulator Transcription 56460696 Common fepA_1 TonB dependent receptor for iron chelates IL1592 44 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 56459872 Common - Secreted protein with uncharacterized domain IL0763 27 COG1262 COG1262, Uncharacterized conserved protein Function unknown 56459861 Common ispD 4-diphosphocytidyl-2-methyl-D-erithritol synthase IL0752 195 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 56461093 Common - NAD-dependent aldehyde dehydrogenase IL1993 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 56459879 Common thiH thiamine biosynthesis protein ThiH IL0770 56 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 56460748 Common qseC_2 Signal transduction histidine kinase IL1647 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 56460036 Common ispE 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase IL0928 189 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 56459906 Common sodA Superoxide dismutase, Mn dependent IL0798 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 56461229 Common - Probable sulfate permease, MFS superfamily IL2129 160 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 56459545 Common murD UDP-N-acetylmuramoylalanine-D-glutamate ligase IL0434 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 56459684 Nonpathogen - Predicted secreted protein IL0575 2 None None None 56459377 Common fliL_1 flagellar basal body-associated protein FliL-like protein IL0266 16 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 56459165 Common - Transcriptional regulator, LysR family IL0053 174 COG0583 LysR, Transcriptional regulator Transcription 56460098 Common smpA Outer membrane lipoprotein OmlA (small protein A) IL0990 66 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 56459766 Common - Uncharacterized conserved membrane protein, containing N-terminal Zn-ribbon domain IL0657 17 None None None 56459643 Common - Predicted membrane associated GTPase IL0534 17 COG1160 COG1160, Predicted GTPases General function prediction only 56460858 Common - Intracellular septation protein A IL1757 92 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 56461440 Common - Signaling protein with membrane-bound sensor domain and GGDEF domain IL2340 177 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 56461584 Common rhaR Positive regulator for rhaRS operon, AraC family IL2484 41 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 56460744 Common merR Transcriptional regulator MerR IL1643 138 COG0789 SoxR, Predicted transcriptional regulators Transcription 56460447 Common acpP Acyl carrier protein IL1339 182 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 56460545 Common uppP undecaprenyl pyrophosphate phosphatase IL1437 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 56461710 Common tnsD Transposon Tn7 transposition protein tnsD IL2610 16 None None None 56460563 Common dapE succinyl-diaminopimelate desuccinylase IL1455 212 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 56460053 Common lnt Apolipoprotein N-acyltransferase IL0945 165 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 56459515 Common - ABC-type transport system involved in resistance to organic solvents, permease component IL0404 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 56460874 Common - Predicted esterase IL1774 100 COG0627 COG0627, Predicted esterase General function prediction only 56461493 Common fecA Outer membrane receptor for Fe3+-dicitrate IL2393 95 COG4772 FecA, Outer membrane receptor for Fe3+-dicitrate Inorganic ion transport and metabolism 56460261 Common - hypothetical protein IL1153 15 COG3018 COG3018, Uncharacterized protein conserved in bacteria Function unknown 56461038 Common rpsR Ribosomal protein S18 IL1938 214 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 56460296 Common fliR flagellar biosynthesis protein FliR IL1188 125 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 56459209 Common araC AraC-type DNA-binding domain IL0098 44 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 56461020 Common rpsS 30S ribosomal protein S19 IL1920 246 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 56461649 Common rarD Conserved membrane protein RarD IL2549 102 COG2962 RarD, Predicted permeases General function prediction only 56460255 Common flgB Flagellar basal body protein IL1147 86 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 56459497 Common - hypothetical protein IL0386 55 COG3164 COG3164, Predicted membrane protein Function unknown 56459790 Common - Transposon mobilization protein homolog IL0681 2 None None None 56461352 Common pcnB Poly(A) polymerase IL2252 213 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 56460310 Common fliH_2 Flagellar biosynthesis protein IL1202 227 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 56460713 Common - Transcriptional regulator, LysR family IL1609 190 COG0583 LysR, Transcriptional regulator Transcription 56460312 Common hyfR Probable response regulator of flagellar motility IL1204 170 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 56459751 Common hsdM Type I restriction-modification system methyltransferase subunit IL0642 151 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 56460755 Common intA Integrase IL1654 115 COG0582 XerC, Integrase DNA replication, recombination, and repair 56460938 Common hisH Glutamine amidotransferase IL1838 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 56459272 Common - Secreted subtilisin-like peptidase IL0161 154 COG4935 COG4935, Regulatory P domain of the subtilisin-like proprotein convertases and other proteases Posttranslational modification, protein turnover, chaperones 56461341 Common - Uncharacterized conserved membrane or secreted protein IL2241 16 None None None 56459343 Common - Membrane-associated metallopeptidase, NlpD family IL0232 182 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 56459413 Common - Transcriptional regulator, Cro/CI/xre family IL0302 36 COG2944 COG2944, Predicted transcriptional regulator Transcription 56459556 Common secA preprotein translocase subunit SecA IL0445 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 56460535 Common prpB 2-methylisocitrate lyase IL1427 136 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 56459820 Common metG methionyl-tRNA synthetase IL0711 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 56459159 Common - Transcriptional regulator, DeoR family IL0047 108 COG2378 COG2378, Predicted transcriptional regulator Transcription 56460153 Common nqrF Na(+)-translocating NADH-quinone reductase subunit F IL1045 161 COG2871 NqrF, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF Energy production and conversion 56461446 Common - Predicted aspartyl protease IL2346 52 COG3577 COG3577, Predicted aspartyl protease General function prediction only 56460130 Common - Protein containing C-terminal DadA-like amino acid oxidase domain fused to N-terminal uncharacterized conserved domain IL1022 102 COG4121 COG4121, Uncharacterized conserved protein Function unknown 56460942 Common - Na+-driven multidrug efflux pump IL1842 174 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 56459387 Common - Acylaminoacyl-peptidase IL0276 108 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 56460986 Common - Predicted signal transduction protein IL1886 54 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 56461273 Common - hypothetical protein IL2173 6 None None None 56460829 Common - ABC-type uncharacterized transport system, permease component IL1728 58 COG4137 COG4137, ABC-type uncharacterized transport system, permease component General function prediction only 56460846 Common - hypothetical protein IL1745 141 COG1354 COG1354, Uncharacterized conserved protein Function unknown 56461381 Common groES co-chaperonin GroES IL2281 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 56460833 Common barA Hybrid sensor histidine kinase (HisK, 2 CheY, Hpt domains) IL1732 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 56460968 Common apbA 2-dehydropantoate 2-reductase IL1868 73 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 56460108 Common - hypothetical protein IL1000 26 None None None 56459446 Common hflK Membrane protease, stomatin/prohibitin family IL0335 210 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 56460999 Common rpsE 30S ribosomal protein S5 IL1899 247 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 56461470 Nonpathogen tatA Sec-independent protein secretion pathway component, TatA family IL2370 1 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 56460264 Common - Phosphatidylglycerophosphate synthase IL1156 33 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 56460423 Common - Two domain protein containing GlcD-like FAD/FMN dehydrogenase and GlpC-like Fe-S oxidoreductase IL1315 202 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 56461469 Common tatB Sec-independent protein secretion pathway component, TatA family IL2369 28 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 56459993 Common - hypothetical protein IL0885 97 COG1720 COG1720, Uncharacterized conserved protein Function unknown 56459128 Common sun tRNA and rRNA cytosine-C5-methylase IL0016 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 56460186 Common - Uncharacterized conserved protein, contains TPR repeats IL1078 102 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 56460816 Common - Chemotaxis protein CheY (2 CheY domains) IL1715 222 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 56460116 Common folD 5,10-methylene-tetrahydrofolate dehydrogenase IL1008 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 56461330 Common surA Periplasmic parvulin-like peptidyl-prolyl isomerase (two homologous domains) IL2230 159 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 56459282 Common - hypothetical protein IL0171 10 None None None 56461065 Common exeA General secretion pathway protein, ATPase IL1965 68 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 56460966 Common ppiA Peptidyl-prolyl cis-trans isomerase (rotamase), cyclophilin family IL1866 191 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 56460456 Common - Predicted pseudouridylate synthase, Rlu family IL1348 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 56461388 Common - Predicted tRNA-dihydrouridine synthase IL2288 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 56460133 Common - Predicted extracellular metal-dependent peptidase IL1025 19 None None None 56460949 Common dnaX DNA polymerase III, gamma/tau subunits IL1849 248 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 56459718 Common aceB malate synthase IL0609 99 COG2225 AceB, Malate synthase Energy production and conversion 56459771 Common dsrC Sulfite reductase gamma subunit IL0662 60 COG2920 DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit Inorganic ion transport and metabolism 56461736 Common trmE tRNA modification GTPase TrmE IL2636 229 COG0486 ThdF, Predicted GTPase General function prediction only 56459978 Common mmsA Methylmalonate-semialdehyde dehydrogenase IL0870 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 56460580 Common seqA replication initiation regulator SeqA IL1472 23 COG3057 SeqA, Negative regulator of replication initiationR DNA replication, recombination, and repair 56459654 Common wecE TDP-4-oxo-6-deoxy-D-glucose transaminase IL0545 194 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 56460728 Nonpathogen - hypothetical protein IL1627 1 None None None 56461053 Common parC DNA topoisomerase IV subunit A IL1953 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 56460666 Nonpathogen - hypothetical protein IL1560 1 None None None 56460247 Common flgJ Flagellum-specific muramidase IL1139 72 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 56461515 Common - hypothetical protein IL2415 44 COG4805 COG4805, Uncharacterized protein conserved in bacteria Function unknown 56460499 Common - RNA polymerase sigma factor IL1391 123 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 56461520 Common - EXOIII family exonuclease IL2420 19 COG5018 KapD, Inhibitor of the KinA pathway to sporulation, predicted exonuclease General function prediction only 56460702 Common - Probable NADPH quinone oxidoreductase IL1598 175 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 56459200 Common - Diacylglycerol kinase IL0089 53 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 56459795 Common - HIT family hydrolase IL0686 64 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 56459299 Common - anaerobic ribonucleoside triphosphate reductase IL0188 66 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 56460933 Nonpathogen - hypothetical protein IL1833 1 None None None 56461251 Common - hypothetical protein IL2151 133 COG2860 COG2860, Predicted membrane protein Function unknown 56459135 Common hemF coproporphyrinogen III oxidase IL0023 113 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 56460399 Common - Transcriptional regulator, LysR family IL1291 173 COG0583 LysR, Transcriptional regulator Transcription 56461314 Common tktA transketolase IL2214 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 56459636 Nonpathogen - hypothetical protein IL0526 1 None None None 56459886 Common czcA Co/Zn/Cd efflux system membrane component IL0777 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 56459593 Common natB_2 ABC-type Na+ efflux pump, permease component IL0482 21 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 56459265 Common sufB_1 cysteine desulfurase activator complex subunit SufB IL0154 184 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 56460547 Common lysC aspartate kinase III IL1439 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 56460013 Nonpathogen - Flp pilus assembly protein CpaB IL0905 3 COG3745 CpaB, Flp pilus assembly protein CpaB Intracellular trafficking and secretion 56459724 Common argG argininosuccinate synthase IL0615 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 56459921 Common rseC Positive regulator of sigma E activity IL0813 7 COG3086 RseC, Positive regulator of sigma E activity Signal transduction mechanisms 56461126 Common pulD Type II secretory pathway, component PulD IL2026 142 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 56461008 Common mnhC putative monovalent cation/H+ antiporter subunit C IL1908 96 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 56461439 Common - Outer membrane protein IL2339 23 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 56460166 Common - Na+/H+ antiporter IL1058 99 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 56460527 Common - Signal-transduction protein IL1419 141 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 56461178 Common - hypothetical protein IL2078 56 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 56460522 Common - Catalase IL1414 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 56459294 Common narK Nitrate/nitrite transporter IL0183 63 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 56461621 Common vapI Toxin-antitoxin stability system antidote protein IL2521 65 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 56460520 Common - Predicted permease, DMT superfamily IL1412 183 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 56459754 Nonpathogen - Predicted membrane protein IL0645 1 None None None 56460417 Common - RNA pseudouridylate synthase-family protein IL1309 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 56459471 Common add Adenosine deaminase IL0360 98 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 56461321 Common - Uncharacterized secreted protein IL2221 4 None None None 56460197 Common aspS Aspartyl-tRNA synthetase IL1089 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 56461544 Common - hypothetical protein IL2444 16 None None None 56461001 Common rplF 50S ribosomal protein L6 IL1901 240 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 56461726 Common atpI F0F1-type ATP synthase, subunit I IL2626 7 COG3312 AtpI, F0F1-type ATP synthase, subunit I Energy production and conversion 56461430 Nonpathogen - hypothetical protein IL2330 2 None None None 56459360 Common - hypothetical protein IL0249 12 None None None 56461462 Common trxA Thioredoxin IL2362 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 56459462 Common - Uncharacterized periplasmic binding protein IL0351 6 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 56461408 Common rsd anti-RNA polymerase sigma 70 factor IL2308 24 COG3160 Rsd, Regulator of sigma D Transcription 56461362 Common fbp fructose-1,6-bisphosphatase IL2262 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 56461136 Common pilF Tfp pilus assembly protein PilF IL2036 43 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 56461209 Common pstS ABC-type phosphate transport system, periplasmic component IL2109 113 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 56460953 Common - hypothetical protein IL1853 62 COG3220 COG3220, Uncharacterized protein conserved in bacteria Function unknown 56460539 Nonpathogen - Xaa-Pro aminopeptidase family enzyme IL1431 8 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 56461040 Common rpsF 30S ribosomal protein S6 IL1940 201 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 56459241 Common - Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase related enzyme IL0130 147 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 56459613 Common mutH DNA mismatch repair protein IL0502 29 COG3066 MutH, DNA mismatch repair protein DNA replication, recombination, and repair 56461425 Nonpathogen - hypothetical protein IL2325 1 None None None 56459476 Common mshJ Type II secretory pathway component IL0365 14 None None None 56461553 Common - Imidazolonepropionase HutI IL2453 108 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 56460106 Common - Uncharacterized protein containing a von Willebrand factor type A (vWA) domain IL0998 82 COG2304 COG2304, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 56459405 Nonpathogen - hypothetical protein IL0294 1 None None None 56459428 Common - hypothetical protein IL0317 6 None None None 56461207 Common pstA ABC-type phosphate transport system, permease component IL2107 228 COG4985 COG4985, ABC-type phosphate transport system, auxiliary component Inorganic ion transport and metabolism 56460674 Nonpathogen - Predicted membrane protein IL1568 3 None None None 56460379 Common - Signaling protein with a GAF domain IL1271 82 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 56459830 Common hmgA Homogentisate 1,2-dioxygenase IL0721 53 COG3508 HmgA, Homogentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 56460347 Nonpathogen - hypothetical protein IL1239 2 None None None 56461297 Common - Predicted acetyltransferase, GNAT family IL2197 4 None None None 56460492 Common - hypothetical protein IL1384 63 COG3496 COG3496, Uncharacterized conserved protein Function unknown 56459488 Common mshO Tfp-like pilus assembly protein IL0377 10 COG4966 PilW, Tfp pilus assembly protein PilW Cell motility and secretion / Intracellular trafficking and secretion 56460319 Common pfkA 6-phosphofructokinase IL1211 161 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 56460860 Common - Predicted dehydrogenase IL1759 31 COG4757 COG4757, Predicted alpha/beta hydrolase General function prediction only 56460585 Common - hypothetical protein IL1477 47 COG3268 COG3268, Uncharacterized conserved protein Function unknown 56461628 Common dcm DNA cytosine methylase IL2528 130 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 56460805 Common rmuC DNA recombination protein RmuC IL1704 136 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 56461218 Common - TonB system biopolymer transport component IL2118 74 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 56461084 Common - hypothetical protein IL1984 72 COG2924 COG2924, Uncharacterized protein conserved in bacteria Function unknown 56460759 Common trkG K+ transport system, membrane component IL1658 152 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 56460384 Common - Na+/H+ antiporter IL1276 65 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 56460853 Common - Anthranilate synthase component II IL1752 224 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 56460082 Common folP Dihydropteroate synthase IL0974 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 56459701 Common - Transcriptional regulator, Cro/CI family IL0592 36 COG3636 COG3636, Predicted transcriptional regulator Transcription 56460772 Common abgT_2 Probable p-aminobenzoyl-glutamate transporter IL1671 26 COG2978 AbgT, Putative p-aminobenzoyl-glutamate transporter Coenzyme metabolism 56460129 Common fabB 3-oxoacyl-(acyl-carrier-protein) synthase IL1021 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 56461149 Nonpathogen - hypothetical protein IL2049 1 None None None 56460734 Common - Membrane-fusion protein, RND family efflux system component IL1633 97 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 56460071 Common - lipoprotein NlpI IL0963 69 COG4785 NlpI, Lipoprotein NlpI, contains TPR repeats General function prediction only 56461489 Common maoC Acyl dehydratase IL2389 23 COG2030 MaoC, Acyl dehydratase Lipid metabolism 56459963 Common queF 7-cyano-7-deazaguanine reductase IL0855 71 COG2904 COG2904, Uncharacterized protein conserved in bacteria Function unknown 56459287 Common - Malonyl-CoA-[acyl-carrier-protein] transacylase, putative IL0176 39 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 56460167 Common fbpA ABC-type Fe3+ transport system, periplasmic component IL1059 113 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 56459928 Common - Predicted aminomethyltransferase, GcvT family IL0820 130 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 56461486 Common - 4-coumarate-CoA ligase, putative IL2386 126 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 56460566 Common purC phosphoribosylaminoimidazole-succinocarboxamide synthase IL1458 217 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 56460438 Common ansA cytoplasmic asparaginase I IL1330 137 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 56460064 Common rlpA Rare lipoprotein A IL0956 137 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 56460467 Common serC phosphoserine aminotransferase IL1359 112 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 56460841 Common - hypothetical protein IL1740 88 COG2968 COG2968, Uncharacterized conserved protein Function unknown 56459874 Common thiC thiamine biosynthesis protein ThiC IL0765 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 56461569 Nonpathogen - Predicted secreted protein IL2469 1 None None None 56461256 Common caiC Medium-chain acyl-CoA synthetase IL2156 221 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 56460699 Common - Conserved secreted protein, containing N-terminal phosphoesterase domain of PHP family IL1595 11 None None None 56459372 Common sulA SOS-response cell division inhibitor IL0261 2 None None None 56461677 Common oxyR Transcriptional regulator of lysR family IL2577 183 COG0583 LysR, Transcriptional regulator Transcription 56461280 Common - hypothetical protein IL2180 21 COG5339 COG5339, Uncharacterized protein conserved in bacteria Function unknown 56459501 Common pmbA Predicted inactivated Zn-dependent protease IL0390 158 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 56461435 Common - hypothetical protein IL2335 2 None None None 56460154 Common nqrE Na(+)-translocating NADH-quinone reductase subunit E IL1046 76 COG2209 NqrE, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE Energy production and conversion 56459583 Common mdh malate dehydrogenase IL0472 181 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 56460646 Nonpathogen - OmpA-like membrane protein IL1540 3 None None None 56460598 Nonpathogen - hypothetical protein IL1490 3 None None None 56459349 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase IL0238 180 COG0756 Dut, dUTPase Nucleotide transport and metabolism 56459252 Common - 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase IL0141 26 COG4706 COG4706, Predicted 3-hydroxylacyl-(acyl carrier protein) dehydratase Lipid metabolism 56461367 Common - Signaling protein (CHEY,EAL,GGDEF domains) IL2267 168 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 56460926 Common rnd Ribonuclease D IL1826 104 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 56460358 Common - Acetyltransferase, GNAT family IL1250 4 COG0456 RimI, Acetyltransferases General function prediction only 56460436 Common - Nitroreductase family protein IL1328 78 COG0778 NfnB, Nitroreductase Energy production and conversion 56459893 Common - SAM-dependent methyltransferase IL0784 40 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 56459398 Nonpathogen - hypothetical protein IL0287 1 None None None 56460093 Common dnaJ DnaJ molecular chaperone IL0985 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 56460035 Common hemM Outer membrane lipoprotein involved in outer membrane biogenesis IL0927 40 COG3017 LolB, Outer membrane lipoprotein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 56459914 Common acpS Phosphopantetheinyl transferase (holo-ACP synthase) IL0806 160 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 56459686 Common - hypothetical protein IL0577 7 None None None 56461086 Common proA Gamma-glutamyl phosphate reductase IL1986 187 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 56461241 Common nusB Transcription termination factor NusB IL2141 188 COG0781 NusB, Transcription termination factor Transcription 56460307 Common fliG flagellar motor switch protein G IL1199 125 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 56461567 Common mrcA Peptidoglycan synthetase IL2467 200 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 56461505 Common - ABC-type multidrug transport system, permease component IL2405 156 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 56460917 Common - hypothetical protein IL1817 12 None None None 56459233 Common phrB_2 Deoxyribodipyrimidine photolyase IL0122 131 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 56460720 Common tra5_4 Transposase Tra5 related protein IL1616 132 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 56459732 Common - Glutathione S-transferase related protein IL0623 109 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 56460896 Common rnfC electron transport complex protein RnfC IL1796 88 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 56460895 Common rnfB electron transport complex protein RnfB IL1795 119 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 56461606 Common - hypothetical protein IL2506 81 COG3146 COG3146, Uncharacterized protein conserved in bacteria Function unknown 56461716 Common glmS Glucosamine-fructose-6-phosphate aminotransferase IL2616 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 56459489 Nonpathogen mshP Type II secretory pathway component IL0378 1 COG4726 PilX, Tfp pilus assembly protein PilX Cell motility and secretion / Intracellular trafficking and secretion 56459429 Common - Signaling protein with a periplasmic amino acid-binding domain, GGDEF and EAL domains IL0318 190 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 56460743 Common - hypothetical protein IL1642 81 COG1742 COG1742, Uncharacterized conserved protein Function unknown 56459564 Nonpathogen pppD Pilin protein PilA IL0453 1 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 56460216 Common - Uncharacterized conserved protein, related to C-terminal FlhB domain IL1108 36 COG2257 COG2257, Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB Function unknown 56461264 Common glnK Nitrogen regulatory protein PII IL2164 187 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 56459844 Common sapC ABC-type antimicrobial peptide transport system, permease component IL0735 222 COG4171 SapC, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 56461165 Common - hypothetical protein IL2065 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 56459663 Common - CMP-N-acetylneuraminic acid synthetase IL0554 72 COG1083 NeuA, CMP-N-acetylneuraminic acid synthetase Cell envelope biogenesis, outer membrane 56459273 Common - Secreted subtilisin-like peptidase IL0162 107 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 56461642 Common - Small-conductance mechanosensitive channel IL2542 42 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 56460338 Common - Amino acid transporter IL1230 119 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 56460483 Common - 2-hydroxy-3-oxopropionate reductase IL1375 190 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 56459614 Common - dinucleoside polyphosphate hydrolase IL0503 113 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 56459640 Common - hypothetical protein IL0531 4 None None None 56459451 Common nusG Transcription antiterminator NusG IL0340 215 COG0250 NusG, Transcription antiterminator Transcription 56459482 Common mshG Type II secretory pathway IL0371 145 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 56459713 Common - Signal transduction histidine kinase (contains GAF domain) IL0604 221 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 56459968 Nonpathogen - hypothetical protein IL0860 1 None None None 56459213 Common - 3-phytase IL0102 19 COG4247 Phy, 3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase) Lipid metabolism 56460939 Common hisA Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase IL1839 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 56461533 Common cpxA Signal transduction histidine kinase (contains HAMP domain) IL2433 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 56459388 Common - DNA-binding transcriptional repressor FabR IL0277 43 COG1309 AcrR, Transcriptional regulator Transcription 56461013 Common - hypothetical protein IL1913 15 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 56459293 Common narL DNA-binding response regulator in two-component regulatory system with NarX (or NarQ) IL0182 220 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 56460847 Common - Possible translation factor, Sua5/YciO/YrdC/YwlC family IL1746 213 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 56459409 Common - Signaling protein with membrane-bound sensor domain and GGDEF domain IL0298 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 56459782 Common infA Translation initiation factor 1 IL0673 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 56461288 Nonpathogen - hypothetical protein IL2188 1 None None None 56461618 Common gufA Predicted divalent heavy-metal cations transporter IL2518 85 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 56461471 Common ubiB_2 Predicted protein kinase IL2371 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 56460448 Common fabG 3-oxoacyl-(acyl carrier protein) reductase, putative IL1340 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 56461049 Common holC DNA polymerase III chi subunit IL1949 49 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 56460808 Common - NTP pyrophosphohydrolase, NUDIX family IL1707 130 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 56460026 Common - Transcriptional regulator, TetR family IL0918 76 COG1309 AcrR, Transcriptional regulator Transcription 56460237 Common ribF FAD synthase IL1129 211 COG0196 RibF, FAD synthase Coenzyme metabolism 56460554 Common - MoxR-like ATPase IL1446 97 COG0714 COG0714, MoxR-like ATPases General function prediction only 56460875 Common - Il-IS_1, transposase IL1774.1 105 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 56461114 Common - O-acetylhomoserine sulfhydrylase IL2014 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 56461104 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase IL2004 200 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 56461494 Common - Glutathione synthase IL2394 10 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 56461611 Common fhuE_2 Outer membrane receptor for ferric siderophore IL2511 108 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 56460653 Common - Zn-dependent enzyme from deacylase/carboxypeptidase superfamily IL1547 11 COG3608 COG3608, Predicted deacylase General function prediction only 56460431 Common bioF 7-keto-8-aminopelargonate synthetase IL1323 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 56461035 Common - hypothetical protein IL1935 3 None None None 56459903 Common - Outer membrane receptor for ferric siderophore IL0795 107 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 56459166 Common - DNA-directed RNA polymerase specialized sigma subunit IL0054 106 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 56459185 Common ptrB Protease II IL0074 100 COG1770 PtrB, Protease II Amino acid transport and metabolism 56461302 Common rpsU 30S ribosomal protein S21 IL2202 106 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 56459779 Common trxB Thioredoxin reductase IL0670 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 56460143 Common miaE tRNA-(ms[2]io[6]A)-hydroxylase IL1035 24 None None None 56460134 Common - Acyl-CoA thioester hydrolase IL1026 45 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 161761291 Common pdhR transcriptional regulator PdhR IL0457 151 COG2186 FadR, Transcriptional regulators Transcription 56461246 Common - hypothetical protein IL2146 89 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 56459435 Common - 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase IL0324 197 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 56461592 Common - Predicted nucleoside-diphosphate-sugar epimerase IL2492 93 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 56461050 Common valS Valyl-tRNA synthetase IL1950 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 56460633 Common - Aspartate carbamoyltransferase, catalytic chain IL1527 239 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 56459177 Common trxC Thioredoxin related protein IL0066 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 56461145 Nonpathogen - Predicted membrane protein IL2045 1 None None None 56461403 Common ugpQ Glycerophosphoryl diester phosphodiesterase IL2303 161 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 56460912 Common - hypothetical protein IL1812 6 None None None 56459977 Common caiA Acyl-CoA dehydrogenase family protein IL0869 167 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 56460619 Common - ABC-type multidrug transport system, ATPase and permease components IL1513 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 56461334 Common apaH diadenosine tetraphosphatase IL2234 89 COG0639 ApaH, Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Signal transduction mechanisms 56460788 Common mesJ ATPase of the PP-loop superfamily IL1687 207 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 56460518 Common - Alcohol dehydrogenase, class IV IL1410 173 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 56459789 Nonpathogen - hypothetical protein IL0680 1 None None None 56461638 Common - Conserved protein containing a Zn-ribbon motif IL2538 7 None None None 56459796 Common - Alpha/beta superfamily hydrolase IL0687 11 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 56460978 Common - Mg-dependent DNase homolog IL1878 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 56461073 Common pilT PilT IL1973 173 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 56459647 Common ugd UDP-glucose 6-dehydrogenase IL0538 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 56459307 Common norR anaerobic nitric oxide reductase transcription regulator IL0196 168 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 56460476 Common - Asparaginase family protein IL1368 84 COG1446 COG1446, Asparaginase Amino acid transport and metabolism 56460916 Common - Acetyltransferase, GNAT family IL1816 6 COG0456 RimI, Acetyltransferases General function prediction only 56459604 Common rsmC 16S RNA G1207 methylase RsmC IL0493 90 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 56460397 Common - RelE/ParE family protein, cytotoxic translational repressor of toxin-antitoxin stability system IL1289 19 COG3668 ParE, Plasmid stabilization system protein General function prediction only 56461194 Common gcvT glycine cleavage system aminomethyltransferase T IL2094 179 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 56461324 Common - Predicted pseudouridylate synthase, Rlu family IL2224 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 56459802 Common asnA asparagine synthetase AsnA IL0693 31 COG2502 AsnA, Asparagine synthetase A Amino acid transport and metabolism 56459217 Common - N-terminal Zn-ribbon domain fused to SAM-dependent methyltransferase IL0106 23 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 56459335 Nonpathogen - hypothetical protein IL0224 1 COG3776 COG3776, Predicted membrane protein Function unknown 56461067 Common folK_2 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase IL1967 58 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 56460753 Common mdoB Phosphoglycerol transferase IL1652 65 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 56460950 Common apt adenine phosphoribosyltransferase IL1850 188 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 56460292 Common comL Competence lipoprotein ComL IL1184 124 COG4105 ComL, DNA uptake lipoprotein General function prediction only 56459300 Common - Na+/H+ antiporter NhaD IL0189 43 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 56459709 Common azu Azurin IL0600 21 COG3241 COG3241, Azurin Energy production and conversion 56459941 Common lpxA UDP-N-acetylglucosamine acyltransferase IL0833 158 COG1043 LpxA, Acyl- acyl carrier protein 56459702 Common - hypothetical protein IL0593 42 COG3657 COG3657, Uncharacterized protein conserved in bacteria Function unknown 56459535 Common lppC Putative lipoprotein IL0424 40 COG3107 LppC, Putative lipoprotein General function prediction only 56461696 Common - Probable phosphoserine phosphatase, HAD-superfamily hydrolase IL2596 73 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 56460272 Common - Predicted regulatory protein containing AraC-type DNA-binding domain and DSBH domain IL1164 127 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 56460624 Common - ABC-type transport system, involved in lipoprotein release, permease component IL1518 169 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 56460282 Nonpathogen - Predicted S-adenosylmethionine-dependent methyltransferase IL1174 4 None None None 56461211 Common phoB Positive response regulator for pho regulon (CheY-wHTH) IL2111 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 56461671 Common dsbA Probable disulfide isomerase IL2571 61 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 56459314 Common - hypothetical protein IL0203 18 None None None 56460289 Common clpB ATP-binding subunit of Clp protease and DnaK/DnaJ chaperones IL1181 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 56459420 Nonpathogen - hypothetical protein IL0309 2 None None None 56459244 Common - Predicted acyltransferase, LSAT/HtrB family IL0133 41 COG4261 COG4261, Predicted acyltransferase General function prediction only 56459143 Common cysE Serine acetyltransferase IL0031 210 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 56460327 Common - hypothetical protein IL1219 8 None None None 56459369 Common coxG cytochrome C oxidase assembly protein IL0258 68 COG3175 COX11, Cytochrome oxidase assembly factor Posttranslational modification, protein turnover, chaperones 56459571 Common lpd dihydrolipoamide dehydrogenase IL0460 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 56460007 Nonpathogen - Uncharacterized conserved secreted protein, containing TPR repeats IL0899 1 None None None 56460120 Common purF amidophosphoribosyltransferase IL1012 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 56459411 Common lplA Lipoate-protein ligase A IL0300 79 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 56460706 Common - SAM-dependent methyltransferase IL1602 37 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 56461732 Common - Ser/Thr protein phosphatase, DSPc family IL2632 13 COG3453 COG3453, Uncharacterized protein conserved in bacteria Function unknown 56461396 Common - Mn2+/Fe2+ transporter, NRAMP family IL2296 105 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 56460220 Common - ATPase involved in chromosome partitioning, Soj/ParA family IL1112 197 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 56460012 Common - possible Flp pilus assembly protein CpaC IL0904 139 COG4964 CpaC, Flp pilus assembly protein, secretin CpaC Intracellular trafficking and secretion 56459628 Common - Acylaminoacyl-peptidase IL0517 186 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 56460040 Common - translation-associated GTPase IL0932 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 56460763 Common purN Folate-dependent phosphoribosylglycinamide formyltransferase IL1662 224 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 56459619 Common - Transposase related protein IL0508 32 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 56460505 Common rpmI 50S ribosomal protein L35 IL1397 171 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 56459812 Common - Glycosyltransferase IL0703 99 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 56459445 Common hflX GTPase, HflX IL0334 232 COG2262 HflX, GTPases General function prediction only 56460229 Nonpathogen - Prepilin peptidase dependent protein A-like protein IL1121 1 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 56461153 Common - Potential redox protein IL2053 25 COG3011 COG3011, Uncharacterized protein conserved in bacteria Function unknown 56461424 Common - D-ribulose-5-phosphate 3-epimerase IL2324 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 56461708 Common - Site-specific DNA-methyltransferase IL2608 4 COG2263 COG2263, Predicted RNA methylase Translation, ribosomal structure and biogenesis 56460851 Common - Carboxypeptidase-related protein IL1750 37 COG2939 COG2939, Carboxypeptidase C (cathepsin A) Amino acid transport and metabolism 56460322 Common tra5_3 Transposase Tra5 related protein IL1214 136 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 56459192 Common - Transcriptional regulator, MarR family IL0081 89 COG1846 MarR, Transcriptional regulators Transcription 56459546 Common ftsW Bacterial cell division membrane protein IL0435 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 56460076 Common infB translation initiation factor IF-2 IL0968 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 56460089 Common carA carbamoyl phosphate synthase small subunit IL0981 235 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 56460196 Common - hypothetical protein IL1088 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 56459170 Common hipA HipA IL0059 64 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 56460865 Common - Lipoprotein A family protein IL1764 136 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 56460771 Common rnhB Ribonuclease HII IL1670 207 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 56461295 Common - hypothetical protein IL2195 6 None None None 56460990 Common rplQ 50S ribosomal protein L17 IL1890 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 56461254 Common - Outer membrane protein IL2154 114 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 56461205 Common phoU transcriptional regulator PhoU IL2105 203 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 56459145 Common - Cold shock protein IL0033 180 COG1278 CspC, Cold shock proteins Transcription 56461139 Common msrA Peptide methionine sulfoxide reductase IL2039 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 56460613 Common sdhC Succinate dehydrogenase/fumarate reductase cytochrome b subunit IL1507 86 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 56460739 Common - Outer membrane protein, probably efflux family IL1638 21 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 56460490 Common - hypothetical protein IL1382 22 None None None 56460014 Nonpathogen - Hypothetical protein, IL_1 family IL0906 1 None None None 56461595 Common - hypothetical protein IL2495 30 COG3310 COG3310, Uncharacterized protein conserved in bacteria Function unknown 56461583 Common - Metal dependent amidohydrolase IL2483 59 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 56460732 Common - Integrase/recombinase, XerC/XerD family IL1631 46 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 56461212 Common - Possible malate permease IL2112 98 COG0679 COG0679, Predicted permeases General function prediction only 56460757 Common nemA NADH:flavin oxidoreductase, Old Yellow Enzyme family IL1656 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 56461227 Common - Permease of the major facilitator superfamily IL2127 30 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 56460087 Common greA Transcription elongation factor GreA IL0979 204 COG0782 GreA, Transcription elongation factor Transcription 56460856 Common trpB tryptophan synthase subunit beta IL1755 224 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 56460415 Common bax Predicted peptidoglycan hydrolase, FlgJ family IL1307 31 COG2992 Bax, Uncharacterized FlgJ-related protein General function prediction only 56460042 Common - hypothetical protein IL0934 14 None None None 56461665 Common - Carbonic anhydrase/acetyltransferase, isoleucine patch superfamily IL2565 186 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 56459832 Common tyrR Transcriptional regulator of aromatic amino acids metabolism IL0723 171 COG3283 TyrR, Transcriptional regulator of aromatic amino acids metabolism Transcription / Amino acid transport and metabolism 56460668 Common - hypothetical protein IL1562 27 COG3402 COG3402, Uncharacterized conserved protein Function unknown 56460429 Common bioD Dethiobiotin synthetase IL1321 104 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 56461484 Common - Transcriptional regulator, TetR family IL2384 107 COG1309 AcrR, Transcriptional regulator Transcription 56459594 Common ordL D-amino acid oxidase family protein (deaminating) IL0483 101 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 56460073 Common rpsO Ribosomal protein S15 IL0965 209 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 56460774 Common - Methyl-accepting chemotaxis protein (2 PAS,MCP domains) IL1673 124 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 56460337 Common - Membrane associated glutaredoxin IL1229 18 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 56459289 Common - Glutaryl-CoA dehydrogenase IL0178 162 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 56459955 Common glnD UTP:GlnB (protein PII) uridylyltransferase IL0847 123 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 56460678 Common - hypothetical protein IL1572 2 None None None 56460190 Common exbD Biopolymer transport protein IL1082 142 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 56459924 Common rpoE RNA polymerase sigma factor RpoE IL0816 173 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 56460065 Common dacA D-alanyl-D-alanine carboxypeptidase IL0957 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 56460465 Common aroA 5-enolpyruvylshikimate-3-phosphate synthase IL1357 228 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 56461474 Common recG DNA helicase RecJ IL2374 213 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 56459884 Common - hypothetical protein IL0775 38 COG1714 COG1714, Predicted membrane protein/domain Function unknown 56459634 Common - NADH dehydrogenase subunit L IL0524 204 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 56459498 Common - Predicted amidohydrolase, nitrilase family IL0387 204 COG0388 COG0388, Predicted amidohydrolase General function prediction only 56459465 Common uvrA Excinuclease ATPase subunit, UvrA IL0354 239 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 56460768 Common bcr Sugar permease, MFS-like IL1667 226 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 56461167 Common - DSBH domain containing protein IL2067 18 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 56460340 Common copD Copper export protein IL1232 5 COG1276 PcoD, Putative copper export protein Inorganic ion transport and metabolism 56460232 Nonpathogen - Type II secretion pathway related protein IL1124 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 56460903 Common ahpC Peroxiredoxin, AhpC/Tsa family IL1803 229 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 56459690 Common - hypothetical protein IL0581 22 None None None 56461176 Common - Catabolite gene activator protein IL2076 28 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 56461148 Common - RelE/ParE family protein IL2048 10 COG1158 Rho, Transcription termination factor Transcription 56459473 Common pyrC dihydroorotase IL0362 87 COG0418 PyrC, Dihydroorotase Nucleotide transport and metabolism 56460583 Common fldA flavodoxin FldA IL1475 74 COG0716 FldA, Flavodoxins Energy production and conversion 56460929 Common slp Starvation-inducible outer membrane lipoprotein IL1829 30 COG3065 Slp, Starvation-inducible outer membrane lipoprotein Cell envelope biogenesis, outer membrane 56460103 Common - MoxR-like ATPase IL0995 180 COG0714 COG0714, MoxR-like ATPases General function prediction only 56460383 Common - Na+-dependent transporter of the SNF family IL1275 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 56461552 Common farR Transcriptional regulator of succinylCoA synthetase operon IL2452 119 COG2188 PhnF, Transcriptional regulators Transcription 56460525 Common - Outer membrane protein, porin family IL1417 7 None None None 56461728 Common parA ATPase involved in chromosome partitioning, Soj/ParA family IL2628 221 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 56460984 Common rimI Acyltransferase for 30S ribosomal subunit protein S18, GNAT family IL1884 173 COG0456 RimI, Acetyltransferases General function prediction only 56461724 Common atpE F0F1-type ATP synthase, subunit c IL2624 67 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 56460993 Common rpsK 30S ribosomal protein S11 IL1893 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 56459699 Common rfaH Transcription antiterminator RfaH IL0590 95 COG0250 NusG, Transcription antiterminator Transcription 56459221 Common - Short-chain alcohol dehydrogenase of unknown specificity IL0110 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 56459722 Common argB acetylglutamate kinase IL0613 199 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 56459835 Common - Methionine gamma-lyase IL0726 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 56459700 Common purL phosphoribosylformylglycinamidine synthase IL0591 233 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 56460976 Common serB_2 Phosphoserine phosphatase IL1876 155 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 56460420 Common purB adenylosuccinate lyase IL1312 234 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 56461660 Common hemX Regulator of HemA biosynthesis IL2560 31 COG2959 HemX, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 56459442 Common mutL DNA mismatch repair enzyme, ATPase IL0331 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 56461006 Common rplN 50S ribosomal protein L14 IL1906 247 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 56461025 Common rpsJ 30S ribosomal protein S10 IL1925 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 56459625 Common - Electron transfer flavoprotein, beta subunit IL0514 153 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 56461483 Common cynX Cyanate permease IL2383 76 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 56459262 Common csdA Selenocysteine lyase/Cysteine desulfurase IL0151 238 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 56460725 Common - LigB family enzyme IL1622 86 COG3384 COG3384, Uncharacterized conserved protein Function unknown 56460451 Common plsX fatty acid/phospholipid synthesis protein IL1343 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 56460294 Common nadE NAD synthetase IL1186 203 COG0171 NadE, NAD synthase Coenzyme metabolism 56459707 Common sfcA Malic enzyme IL0598 202 COG0281 SfcA, Malic enzyme Energy production and conversion 56461406 Common hemE Uroporphyrinogen-III decarboxylase IL2306 182 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 56460884 Common - disrupted signaling protein (xGGDEF and EAL domains) IL1784 162 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 56460811 Common - Signal transduction histidine kinase IL1710 10 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 56460806 Common fumB Fumarase B IL1705 148 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 56460320 Common speB Agmatinase IL1212 124 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 56460641 Common - Na(+)/nucleoside cotransporter IL1535 68 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 56459195 Common - Calcineurin phosphohydrolase superfamily protein IL0084 74 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 56461685 Common ilvB acetolactate synthase IL2585 223 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 56460497 Common - hypothetical protein IL1389 78 COG3272 COG3272, Uncharacterized conserved protein Function unknown 56460943 Common - Alpha/beta superfamily hydrolase IL1843 119 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 56461355 Common panC Panthothenate synthetase IL2255 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 56461375 Common - Truncated class II lysyl-tRNA synthetase IL2275 204 COG2269 COG2269, Truncated, possibly inactive, lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 56461517 Common - Predicted transcriptional regulator containing Fic and HTH-like domain IL2417 103 COG3177 COG3177, Uncharacterized conserved protein Function unknown 56459743 Common - Il-IS_2, transposase IL0633.1 64 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 56460936 Common hisC Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase IL1836 235 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 56460317 Common pdxH Pyridoxamine phosphate oxidase IL1209 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 56461275 Common - Small-conductance mechanosensitive channel IL2175 84 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 56459321 Nonpathogen - hypothetical protein IL0210 1 None None None 56459478 Common mshL Type II secretory pathway IL0367 144 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 56459972 Common - Alpha/beta superfamily hydrolase IL0864 36 COG3571 COG3571, Predicted hydrolase of the alpha/beta-hydrolase fold General function prediction only 56461455 Common licA Choline kinase involved in LPS biosynthesis IL2355 25 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 56460115 Common - hypothetical protein IL1007 2 None None None 56460446 Common pabC 4-amino-4-deoxychorismate lyase IL1338 69 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 56461441 Common - hypothetical protein IL2341 97 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 56459277 Common - Response regulator with a Fis-type DNA-binding domain (CheY, Fis domains) IL0166 126 COG4567 COG4567, Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain Signal transduction mechanisms / Transcription 56461546 Common csgA Cell-cell signaling protein CsgA IL2446 61 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 56460110 Common hupB Bacterial nucleoid DNA-binding protein HU-beta IL1002 205 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 56459525 Common rplM 50S ribosomal protein L13 IL0414 237 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 56459361 Common dinF Na+-driven multidrug efflux pump IL0250 166 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 56461270 Common chaC Uncharacterized protein involved in cation transport IL2170 44 COG3703 ChaC, Uncharacterized protein involved in cation transport Inorganic ion transport and metabolism 56461733 Common - Lactoylglutathione lyase IL2633 118 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 56460241 Common fliS Flagellin-specific chaperone FliS IL1133 81 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 56459823 Common - HIT family hydrolase IL0714 228 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 56460458 Common comEA DNA uptake protein, DNA-binding IL1350 81 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 56461575 Common dam DNA adenine methylase IL2475 95 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 56459653 Common - 3-oxoacyl-(acyl carrier protein) reductase, putative IL0544 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 56460818 Common - Secreted enzyme, contains two amidohydrolase related domains IL1717 47 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 56459491 Common - Secreted protein with uncharacterized domain IL0380 103 COG1262 COG1262, Uncharacterized conserved protein Function unknown 56461312 Common pgk phosphoglycerate kinase IL2212 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 56460184 Common - IS4-like transposase IL1076 27 COG3385 COG3385, FOG: Transposase and inactivated derivatives DNA replication, recombination, and repair 56459715 Common - Transcriptional regulator, LysR family IL0606 113 COG0583 LysR, Transcriptional regulator Transcription 56461369 Common - hypothetical protein IL2269 81 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 56460571 Common - Putative Zn-dependent HtpX-like protease IL1463 129 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 56459263 Common sufB_2 Cysteine desulfurase activator SufB IL0152 177 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 56460711 Common - Predicted DNA-binding protein, possible transcriptional regulator IL1607 41 None None None 56459672 Common - Sugar transferase IL0563 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 56460156 Common nqrC Na(+)-translocating NADH-quinone reductase subunit C IL1048 50 COG2869 NqrC, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC Energy production and conversion 56461684 Nonpathogen - hypothetical protein IL2584 6 None None None 56460201 Common - Transcriptional regulator, LysR family IL1093 111 COG0583 LysR, Transcriptional regulator Transcription 56460471 Common nrdA ribonucleotide-diphosphate reductase subunit alpha IL1363 210 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 56459958 Common - hypothetical protein IL0850 33 COG3098 COG3098, Uncharacterized protein conserved in bacteria Function unknown 56461590 Common fepA_2 Outer membrane receptor for ferrienterochelin and colicins IL2490 129 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 56461623 Nonpathogen - hypothetical protein IL2523 1 None None None 56459770 Nonpathogen dsrH hypothetical protein IL0661 1 None None None 56461032 Common cheX Chemotaxis protein CheX IL1932 28 COG1406 COG1406, Predicted inhibitor of MCP methylation, homolog of CheC Cell motility and secretion 56460718 Common - hypothetical protein IL1614 9 None None None 56459207 Common qseC_1 Signal transduction histidine kinase (contains HAMP domain) IL0096 214 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 56461656 Common lysA Diaminopimelate decarboxylase IL2556 218 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 56460655 Common - Probable arabinose efflux permease, MFS-like IL1549 197 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 56461022 Common rplW 50S ribosomal protein L23 IL1922 220 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 56459760 Common intB Integrase IL0651 100 COG0582 XerC, Integrase DNA replication, recombination, and repair 56460373 Common - hypothetical protein IL1265 7 None None None 56460822 Common tyrA bifunctional chorismate mutase/prephenate dehydrogenase IL1721 79 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 56461372 Common - Il-IS_1, transposase IL2271.1 105 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 56460058 Common - Nicotinic acid mononucleotide adenylyltransferase IL0950 179 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 56459351 Common radC RadC IL0240 179 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 56461737 Common yidC Preprotein translocase subunit YidC IL2637 215 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 56460257 Common - Chemotaxis protein CheV IL1149 178 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 56459402 Nonpathogen - hypothetical protein IL0291 2 None None None 56461121 Common - Type II secretory pathway, pseudopilin PulG-like IL2021 9 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 56459867 Common - hypothetical protein IL0758 3 COG3686 COG3686, Predicted membrane protein Function unknown 56461343 Common - hypothetical protein IL2243 97 COG1981 COG1981, Predicted membrane protein Function unknown 56460920 Common - Uncharacterized conserved protein, containing metal-binding domain IL1820 3 None None None 56460964 Common - 3-oxoacyl-(acyl carrier protein) synthase III IL1864 206 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 56461448 Common - hypothetical protein IL2348 42 COG1238 COG1238, Predicted membrane protein Function unknown 56461092 Common - Succinate-semialdehyde dehydrogenase IL1992 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 56461491 Common - Predicted transcriptional regulator, YjeB/RRF2 family IL2391 140 COG1959 COG1959, Predicted transcriptional regulator Transcription 56460210 Common ccmE cytochrome c-type biogenesis protein CcmE IL1102 92 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 56461134 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IL2034 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 56459999 Common - hypothetical protein IL0891 31 COG3101 COG3101, Uncharacterized protein conserved in bacteria Function unknown 56460351 Common soxR_4 Transcriptional regulator, MerR family IL1243 137 COG0789 SoxR, Predicted transcriptional regulators Transcription 56459882 Common pyrG CTP synthetase IL0773 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 56460751 Common - PAP2 (acid phosphatase) superfamily membrane protein IL1650 23 COG3907 COG3907, PAP2 (acid phosphatase) superfamily protein General function prediction only 56459780 Common aat leucyl/phenylalanyl-tRNA--protein transferase IL0671 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 56460017 Nonpathogen - Uncharacterized secreted protein IL0909 3 None None None 56461106 Common - Response regulator, LuxR family (CheY, HTH domains) IL2006 171 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 56460704 Common - Endoribonuclease L-PSP family protein IL1600 78 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 56461163 Nonpathogen - Predicted secreted protein IL2063 1 None None None 56460243 Common flaG FlaG IL1135 12 COG1334 FlaG, Uncharacterized flagellar protein FlaG Cell motility and secretion 56460051 Common - Predicted metal-dependent hydrolase IL0943 190 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 56460230 Nonpathogen - Prepilin peptidase dependent protein B-like protein IL1122 1 COG4795 PulJ, Type II secretory pathway, component PulJ Intracellular trafficking and secretion 56460765 Common - hypothetical protein IL1664 13 None None None 56459909 Common soxR_2 Transcriptional regulator, MerR family IL0801 92 COG0789 SoxR, Predicted transcriptional regulators Transcription 56459705 Common - Cation transport ATPase IL0596 233 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 56461269 Common - Membrane-anchored signaling protein (PAS,GGDEF,EAL doamins) IL2169 176 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 56459665 Common wecC UDP-N-acetyl-D-mannosaminuronate dehydrogenase IL0556 207 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 56461224 Common arcC/arsR ArsC/ArsR fusion protein IL2124 164 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 56461011 Common mnhF Multisubunit Na+/H+ antiporter, MnhF subunit IL1911 61 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 56459223 Common - Outer membrane protein IL0112 123 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 56459986 Common - Hydroxymethylglutaryl-CoA lyase IL0878 198 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 56459503 Common ptsO Phosphotransferase system, HPr-related protein NPr IL0392 148 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 56460145 Common gltP_2 Na+/H+ - glutamate/aspartate symport protein IL1037 163 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 56461339 Common - Xaa-Pro aminopeptidase IL2239 185 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 56459340 Common rpoH RNA polymerase factor sigma-32 IL0229 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 56461018 Common rpsC Ribosomal protein S3 IL1918 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 56459810 Common acrA Probable acriflavine resistance protein A, RND family efflux system component IL0701 162 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 56459227 Common - Uncharacterized metal-binding protein IL0116 40 COG0748 HugZ, Putative heme iron utilization protein Inorganic ion transport and metabolism 56461182 Nonpathogen - Predicted membrane protein IL2082 1 None None None 56459168 Common - Membrane associated protein containing xre-family DNA-binding HTH domain IL0056 20 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 56460235 Common lspA Lipoprotein signal peptidase IL1127 197 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 56461037 Common rplI Ribosomal protein L9 IL1937 212 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 56459231 Common - Membrane-associated protein IL0120 226 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 56459309 Common mltC Membrane-bound lytic murein transglycosylase C IL0198 135 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 56461600 Common - Alpha-beta superfamily hydrolase IL2500 39 COG4667 COG4667, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 56459521 Common degS Periplasmic trypsin-like serine protease IL0410 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 56461650 Common osmC Organic hydroperoxide reductase IL2550 94 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 161761293 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase IL0142 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 56460568 Common dapA Dihydrodipicolinate synthase IL1460 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 56459548 Common murC_1 UDP-N-acetylmuramate-alanine ligase IL0437 209 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 56459681 Common - hypothetical protein IL0572 14 None None None 56460251 Common flgF Flagella basal body rod protein IL1143 120 COG4787 FlgF, Flagellar basal body rod protein Cell motility and secretion 56460559 Common xthA exonuclease III IL1451 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 56459512 Common - Predicted sugar phosphate isomerase involved in capsule formation IL0401 185 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 56459819 Common mrp ATPase involved in chromosome partitioning IL0710 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 56461304 Common - Serine/threonine protein kinase IL2204 118 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 56460661 Common - Beta-lactamase class C family protein IL1555 69 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 56459809 Common - NADPH:quinone reductase related enzyme IL0700 179 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 56459794 Common - Uncharacterized protein containing Fic domain IL0685 29 COG3177 COG3177, Uncharacterized conserved protein Function unknown 56460248 Common flgI flagellar basal body P-ring protein IL1140 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 56460091 Common gltP_1 Na+/H+ - glutamate/aspartate symport protein IL0983 164 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 56459161 Common - Riboflavin-specific deaminase IL0049 207 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 56461714 Nonpathogen - hypothetical protein IL2614 1 None None None 56459787 Common - Membrane-associated hydrolase of alkaline phosphatase superfamily IL0678 28 COG3083 COG3083, Predicted hydrolase of alkaline phosphatase superfamily General function prediction only 56460136 Common - Outer membrane protein IL1028 112 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 56459197 Nonpathogen - Predicted membrane protein IL0086 1 COG4194 COG4194, Predicted membrane protein General function prediction only 56459254 Common - 3-oxoacyl-(acyl carrier protein) synthase II IL0143 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 56461097 Common - Predicted P-loop ATPase fused to an acetyltransferase IL1997 48 COG1444 COG1444, Predicted P-loop ATPase fused to an acetyltransferase General function prediction only 56459136 Common aroE Shikimate 5-dehydrogenase IL0024 214 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 56459688 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein IL0579 238 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 56460000 Common aroC chorismate synthase IL0892 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 56460370 Common - hypothetical protein IL1262 16 None None None 56460095 Common grpE Molecular chaperone GrpE (heat shock protein) IL0987 231 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 56461244 Common - Acyltransferase family protein IL2144 33 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 56459747 Common - RadC family protein IL0638 56 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 56461116 Common pulN Type II secretory pathway, component PulN IL2016 8 None None None 56460617 Common - Uncharacterized conserved protein, possible metal-binding domain IL1511 95 COG2835 COG2835, Uncharacterized conserved protein Function unknown 56461565 Common metJ transcriptional repressor protein MetJ IL2465 23 COG3060 MetJ, Transcriptional regulator of met regulon Transcription / Amino acid transport and metabolism 56460910 Common - Predicted Zn-dependent hydrolase IL1810 57 COG3228 COG3228, Uncharacterized protein conserved in bacteria Function unknown 56459467 Common ssb Single-stranded DNA-binding protein IL0356 213 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 56459484 Common mshB Pilin protein IL0373 8 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 56460500 Common chrR Transcription negative regulator ChrR IL1392 34 COG3806 ChrR, Transcriptional activator Transcription 56459347 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase IL0236 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 56461608 Common - hypothetical protein IL2508 14 None None None 56460824 Common rplS 50S ribosomal protein L19 IL1723 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 56459374 Common plsB glycerol-3-phosphate acyltransferase IL0263 48 COG2937 PlsB, Glycerol-3-phosphate O-acyltransferase Lipid metabolism 56460402 Common - Membrane-fusion protein homolog IL1294 159 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 56460741 Common - Metal efflux system membrane component (silver efflux pump related) IL1640 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 56461635 Common - Intracellular signaling protein (GAF,GGDEF domains) IL2535 184 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 56459849 Common - Alpha-beta superfamily hydrolase IL0740 134 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 56460485 Common - NIF3 IL1377 118 COG0327 COG0327, Uncharacterized conserved protein Function unknown 56459453 Common rplA 50S ribosomal protein L1 IL0342 248 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 56459541 Common ftsI Cell division protein FtsI IL0430 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 56460176 Common - Methyl-accepting chemotaxis protein with ligand-binding sensor domain and HAMP domain IL1068 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 56460533 Common - aconitate hydratase IL1425 223 COG1048 AcnA, Aconitase A Energy production and conversion 56459246 Common - Predicted thioesterase IL0135 58 COG0824 FcbC, Predicted thioesterase General function prediction only 56459256 Common - Prolyl endopeptidase IL0145 122 COG1505 COG1505, Serine proteases of the peptidase family S9A Amino acid transport and metabolism 56460377 Common - Zn-ribbon protein IL1269 4 None None None 56460516 Common - NtrC family transcriptional regulator IL1408 174 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 56459552 Common ftsZ cell division protein FtsZ IL0441 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 56459877 Common thiS Thiamine biosynthesis protein ThiS IL0768 32 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 56460214 Common ccmA ABC-type transport system involved in cytochrome c biogenesis, ATPase component IL1106 249 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 56459846 Common sapF ABC-type antimicrobial peptide transport system, ATPase component IL0737 249 COG4167 SapF, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 56460556 Common - TPR repeats (SEL1 subfamily) containing protein IL1448 2 None None None 56461503 Common - HlyD family secretion protein IL2403 121 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 56460924 Common - Membrane-bound lytic murein transglycosylase IL1824 103 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 56461286 Common - Secreted protein with uncharacterized domain IL2186 89 COG1262 COG1262, Uncharacterized conserved protein Function unknown 56461189 Common - Predicted ATPase, possibly involved in inorganic ion transport IL2089 18 COG4694 COG4694, Uncharacterized protein conserved in bacteria Function unknown 56460622 Common - ABC-type transport system, involved in lipoprotein release, permease component IL1516 169 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 56461137 Common - hypothetical protein IL2037 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 56460194 Common ruvA Holliday junction resolvasome, DNA-binding subunit IL1086 211 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 56460299 Nonpathogen fliO Flagellar biosynthesis protein IL1191 1 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 56461332 Common ksgA dimethyladenosine transferase IL2232 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 56460604 Common - Ferritin-like DNA-binding protein IL1498 34 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 56461599 Common - Uracil-DNA glycosylase IL2499 65 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 56460078 Common - Alpha-hemolysin-like protein, hlyA family IL0970 160 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 56461644 Common ibpA Molecular chaperone (small heat shock protein) IL2544 82 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 56460902 Common rnt ribonuclease T IL1802 65 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 56460349 Common - Lipoprotein signal peptidase IL1241 196 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 56461461 Common rho transcription termination factor Rho IL2361 201 COG1158 Rho, Transcription termination factor Transcription 56460284 Common - 3'-5' exonuclease IL1176 48 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 56460028 Common kdsA 2-dehydro-3-deoxyphosphooctonate aldolase IL0920 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 56461239 Common pgpA Phosphatidylglycerophosphatase A IL2139 105 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 56461059 Common glnE Glutamine synthetase adenylyltransferase IL1959 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 56460226 Common fleN Antiactivator of flagellar biosynthesis IL1118 163 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 56460629 Common - Extracellular nuclease IL1523 44 COG2374 COG2374, Predicted extracellular nuclease General function prediction only 56460047 Common - FAD-binding oxidoreductase, UbiH/Coq6 family IL0939 128 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 56460122 Common dedD hypothetical protein IL1014 38 COG3147 DedD, Uncharacterized protein conserved in bacteria Function unknown 56461398 Common - Histone deacetylase/AcuC/AphA family protein IL2298 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 56461401 Common - ribosome-associated GTPase IL2301 165 COG1162 COG1162, Predicted GTPases General function prediction only 56461496 Common - Na+/dicarboxylate symporter IL2396 105 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 56459590 Common - hypothetical protein IL0479 4 None None None 56461159 Common - ABC-type transport system, ATPase and permease component IL2059 14 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 56459190 Common - Alkaline phosphatase family protein IL0079 72 COG3211 PhoX, Predicted phosphatase General function prediction only 56459537 Common - Signaling protein with a sensor domain, CHASE, GGDEF and EAL domains IL0426 180 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 56461143 Common suhB Inositol monophosphatase IL2043 207 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 56460995 Nonpathogen rpmJ Ribosomal protein L36 IL1895 1 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 56459951 Common pyrH uridylate kinase IL0843 230 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 56459175 Nonpathogen - hypothetical protein IL0064 3 None None None 56460207 Common ccmH Cytochrome c-type biogenesis protein CcmH IL1099 90 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 56461594 Common - Intracellular signaling protein (PAS,GAF,GGDEF domains) IL2494 179 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 56459358 Common comFC Competence protein IL0247 141 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 56460686 Common - Broad specificity phosphatase, PhoE-like IL1582 9 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 56461659 Common hemD Uroporphyrinogen-III synthase IL2559 39 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 56460610 Common sdhB succinate dehydrogenase iron-sulfur subunit IL1504 205 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 56461426 Common - hypothetical protein IL2326 11 None None None 56460009 Common tadC Flp pilus assembly protein TadC IL0901 74 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 56461563 Common - NADP-dependent malic enzyme IL2463 202 COG0281 SfcA, Malic enzyme Energy production and conversion 56460353 Common - hypothetical protein IL1245 26 COG3784 COG3784, Uncharacterized protein conserved in bacteria Function unknown 56461416 Common - Succinylglutamic semialdehyde dehydrogenase IL2316 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 56459386 Common natB_1 ABC-type Na+ efflux pump, permease component IL0275 37 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 56459422 Common - ABC-type multidrug transport system, permease component IL0311 77 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 56459755 Common - Integrase/recombinase, XerC/XerD family IL0646 51 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 56460507 Common thrS threonyl-tRNA synthetase IL1399 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 56459127 Common trkA potassium transporter peripheral membrane component IL0015 149 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 56460781 Common - Alpha keto acid dehydrogenase complex, E1 component, alpha subunit IL1680 162 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 56459417 Common fadR_1 Transcriptional regulator, FadR family IL0306 137 COG2186 FadR, Transcriptional regulators Transcription 56459612 Common - hypothetical protein IL0501 8 None None None 56459390 Common - hypothetical protein IL0279 5 None None None 56459729 Common - Il-IS_3, transposase IL0619.1 83 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 56460325 Common - Likely secreted protein containing plastocyanin domain IL1217 16 COG4633 COG4633, Uncharacterized protein conserved in bacteria Function unknown 56460873 Common adhC Alcohol dehydrogenase class III IL1773 182 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 56460270 Common - Antitoxin of toxin-antitoxin stability system, StbD family IL1162 23 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 56459316 Common - Cytochrome c5 IL0205 46 COG3245 CycB, Cytochrome c5 Energy production and conversion 56461694 Common - Outer membrane protein IL2594 84 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 56460957 Common - TonB system biopolymer transport component IL1857 74 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 56460981 Common deoB phosphopentomutase IL1881 70 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 56460888 Common - hypothetical protein IL1788 26 COG3205 COG3205, Predicted membrane protein Function unknown 56461730 Common gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA IL2630 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 56460609 Common kgd alpha-ketoglutarate decarboxylase IL1503 147 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 56459938 Common - Pirin-related protein IL0830 146 COG1741 COG1741, Pirin-related protein General function prediction only 56459389 Common - Fatty-acid desaturase IL0278 67 COG1398 OLE1, Fatty-acid desaturase Lipid metabolism 56459183 Common - NAD-dependent aldehyde dehydrogenase IL0072 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 56460615 Common - Lysine 2,3-aminomutase related protein enzyme IL1509 126 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 56461437 Common - Aminopeptidase M1 family protein IL2337 161 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 56460648 Common aidB Acyl-CoA dehydrogenase IL1542 146 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 56459989 Common - Electron transfer flavoprotein-ubiquinone oxidoreductase, putative IL0881 110 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 56460290 Common - hypothetical protein IL1182 174 COG1496 COG1496, Uncharacterized conserved protein Function unknown 56459912 Common relA (p)ppGpp synthetase II IL0804 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 56460495 Common - Ketosteroid isomerase-related protein, cystatin fold IL1387 28 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 56461230 Common uspA UspA-related nucleotide-binding protein IL2130 54 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 56459528 Common - Cytochrome b subunit of the bc complex IL0417 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 56459578 Common - RND family efflux transporter IL0467 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 56460631 Common - bifunctional methionine sulfoxide reductase A/B protein IL1525 206 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 56460914 Common - hypothetical protein IL1814 7 None None None 56461074 Common - Predicted enzyme with a TIM-barrel fold IL1974 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 56459948 Common cdsA CDP-diglyceride synthetase IL0840 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 56461068 Common folB Dihydroneopterin aldolase IL1968 114 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 56460795 Common rnhA Ribonuclease HI IL1694 179 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 56459337 Common ftsY Signal recognition particle GTPase IL0226 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 56461326 Common djlA Dna-J like membrane chaperone protein IL2226 68 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 56461574 Common damX Uncharacterized ATPase, DamX IL2474 19 COG3266 DamX, Uncharacterized protein conserved in bacteria Function unknown 56459606 Nonpathogen - Probable signal transduction protein, containing Hpt domain IL0495 2 None None None 56459800 Common - Short-chain alcohol dehydrogenase of unknown specificity IL0691 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 56461524 Common - Smr domain (Small MutS Related) containing protein IL2424 96 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 56461061 Common putA bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase IL1961 220 COG4230 COG4230, Delta 1-pyrroline-5-carboxylate dehydrogenase Energy production and conversion 56461519 Common - Transcriptional regulator, Cro/CI family IL2419 61 COG1396 HipB, Predicted transcriptional regulators Transcription 56460277 Common - hypothetical protein IL1169 10 None None None 56459215 Common - Pyrazinamidase/nicotinamidase IL0104 128 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 56459475 Common mshI_2 Type II secretory pathway component IL0364 6 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 56459219 Common katG Catalase IL0108 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 56461602 Common - Uncharacterized conserved membrane domain fused to predicted periplasmic domain IL2502 29 COG3656 COG3656, Predicted periplasmic protein Function unknown 56461535 Common glnG Nitrogen regulation protein NRI (CHEY,AAA domains) IL2435 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 56459919 Common lepB Signal peptidase I IL0811 208 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 56461721 Common atpA F0F1 ATP synthase subunit alpha IL2621 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 56461192 Common gcvP_1_2 glycine dehydrogenase IL2092 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 56459639 Common - Predicted exonuclease of the beta-lactamase fold IL0530 125 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 56461047 Common - Predicted permease IL1947 82 COG0795 COG0795, Predicted permeases General function prediction only 56460523 Common - Outer membrane protein IL1415 85 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 56459758 Nonpathogen - hypothetical protein IL0649 1 None None None 56460138 Common - Phosphate acyltransferase family protein IL1030 56 COG3176 COG3176, Putative hemolysin General function prediction only 56460124 Common accD AcetylCoA carboxylase, carboxytransferase component, beta subunit IL1016 219 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 56460909 Common - Probable outer membrane protein IL1809 44 None None None 56459776 Common ftsK DNA segregation ATPase FtsK IL0667 200 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 56461004 Common rplE 50S ribosomal protein L5 IL1904 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 56461669 Common - Phosphate acyltransferase family protein IL2569 30 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 56461548 Common dtd D-tyrosyl-tRNA deacylase IL2448 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 56460101 Common fadJ multifunctional fatty acid oxidation complex subunit alpha IL0993 186 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 56460974 Common sms DNA repair protein RadA IL1874 211 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 56461357 Common - Predicted methyltransferase IL2257 30 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 56459936 Common qor Probable NADPH:quinone reductase IL0828 186 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 56459418 Nonpathogen - hypothetical protein IL0307 1 None None None 56459799 Common - Flavin dependant oxidoreductase, putative IL0690 113 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 56461625 Common - putative antitoxin of the YafO-YafN toxin-antitoxin system IL2525 6 None None None 56459792 Nonpathogen - Predicted secreted protein IL0683 1 None None None 56460049 Common miaB 2-methylthioadenine synthetase IL0941 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 56460927 Common fadD Acyl-CoA synthetase IL1827 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 56461174 Common - Glyoxalase/dioxygenase superfamily protein IL2074 31 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 56459260 Common paaD Predicted metal-sulfur cluster enzyme IL0149 142 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 56460581 Common - Alpha/beta superfamily hydrolase IL1473 174 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 56461550 Common hutH_2 Histidine ammonia-lyase IL2450 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 56459745 Common - RadC family protein IL0636 176 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 56461404 Common - RND family efflux transporter IL2304 178 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 56461443 Common - Methyl-accepting chemotaxis protein (contains HAMP domain) IL2343 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 56459990 Common hns Histone-like protein IL0882 26 COG2916 Hns, DNA-binding protein H-NS General function prediction only 56461379 Common - hypothetical protein IL2279 14 None None None 56459440 Common - Predicted ATPase or kinase IL0329 201 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 56460181 Common - Capsular polyglutamate biosynthesis secreted protein CapB, ATP-dependent mur ligase family IL1073 110 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 56459290 Common fnr Anaerobic regulatory protein IL0179 138 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 56460737 Common - Co/Zn/Cd efflux system membrane component IL1636 63 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 56460021 Common - Organic radical activating enzyme IL0913 170 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 56460219 Common cheW_2 CheW-like domain containing protein IL1111 14 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 56460443 Common holB DNA polymerase III, delta prime subunit, ATPase IL1335 213 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 56461319 Common - Holliday junction resolvase-like protein IL2219 188 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 56460060 Common - hypothetical protein IL0952 167 COG1576 COG1576, Uncharacterized conserved protein Function unknown 56459589 Common folA Dihydrofolate reductase IL0478 149 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 56460161 Nonpathogen - Predicted secreted protein IL1053 1 None None None 56461613 Common - hypothetical protein IL2513 4 None None None 56460400 Common acpD Acyl carrier protein phosphodiesterase IL1292 99 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 56460463 Common rpsA 30S ribosomal protein S1 IL1355 218 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 56459816 Common - hypothetical protein IL0707 110 COG0397 COG0397, Uncharacterized conserved protein Function unknown 56461203 Common rpiA ribose-5-phosphate isomerase A IL2103 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 56460067 Common lipB Lipoate-protein ligase B IL0959 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 56461252 Common - Multidomain protein, contains Na+/proline symporter PutP-like domain, sensory histidine kinase and receiver domain IL2152 222 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 56460882 Common - hypothetical protein IL1782 45 COG2928 COG2928, Uncharacterized conserved protein Function unknown 56461293 Common - Transcriptional regulator, LysR family IL2193 104 COG0583 LysR, Transcriptional regulator Transcription 56461132 Common - hypothetical protein IL2032 64 COG2976 COG2976, Uncharacterized protein conserved in bacteria Function unknown 56459720 Common argE acetylornithine deacetylase IL0611 198 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 56461420 Common - Predicted HD-hydrolase family enzyme IL2320 6 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 56460427 Common aroG 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase IL1319 73 COG3200 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 56461214 Common - TPR repeats containing protein IL2114 36 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 56460992 Common rpsD 30S ribosomal protein S4 IL1892 228 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 56460388 Common pyrD dihydroorotate dehydrogenase 2 IL1280 224 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 56459858 Common surE SurE IL0749 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 56459870 Common - Cytochrome c, monoheme variant IL0761 56 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 56459926 Nonpathogen - hypothetical protein IL0818 1 None None None 56460730 Nonpathogen - Predicted LytTr DNA-binding domain IL1629 1 None None None 56460776 Nonpathogen - hypothetical protein IL1675 7 None None None 56460836 Common oadA pyruvate carboxylase subunit B IL1735 196 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 56461718 Common atpC F0F1-type ATP synthase, epsilon subunit IL2618 170 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 56460075 Common rbfA ribosome-binding factor A IL0967 175 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 56460562 Common - Glutaredoxin family protein IL1454 111 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 56460952 Common - hypothetical protein IL1852 15 COG3219 COG3219, Uncharacterized protein conserved in bacteria Function unknown 56461687 Common - Cation efflux system component IL2587 205 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 56460335 Common - hypothetical protein IL1227 9 None None None 56459596 Common - S-adenosyl-L-homocysteine hydrolase IL0485 178 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 56459283 Common - Probable outer membrane protein IL0172 28 None None None 56461310 Common - Putative salt-induced outer membrane protein IL2210 31 COG3137 COG3137, Putative salt-induced outer membrane protein Cell envelope biogenesis, outer membrane 56459449 Common tufB_1 elongation factor Tu IL0338 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 56460413 Common - universal stress protein UspE IL1305 94 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 56460541 Common - Monomeric isocitrate dehydrogenase IL1433 65 COG2838 Icd, Monomeric isocitrate dehydrogenase Energy production and conversion 56461585 Common - Transcriptional regulator, AraC family IL2485 62 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 56459997 Common - Uncharacterized protein distantly related to polyphosphate/ATP-NAD kinase family IL0889 26 COG3199 COG3199, Uncharacterized conserved protein Function unknown 56460174 Common bfr Bacterioferritin (cytochrome b1) IL1066 105 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 56459762 Common uvrC excinuclease ABC subunit C IL0653 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 56461118 Common pulL Type II secretory pathway, component PulL IL2018 25 COG3297 PulL, Type II secretory pathway, component PulL Intracellular trafficking and secretion 56459670 Nonpathogen - hypothetical protein IL0561 1 None None None 56460434 Common - hypothetical protein IL1326 4 None None None 56459425 Common - Response regulator, LuxR family (CheY, HTH domains) IL0314 214 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 56459519 Common - Predicted transcriptional regulator, BolA superfamily IL0408 43 COG5007 COG5007, Predicted transcriptional regulator, BolA superfamily Transcription 56461499 Nonpathogen - hypothetical protein IL2399 3 None None None 56461383 Common dipZ thiol:disulfide interchange protein precursor IL2283 154 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 56460577 Common - Uncharacterized conserved secreted or membrane protein IL1469 20 COG3249 COG3249, Uncharacterized protein conserved in bacteria Function unknown 56461095 Common - Predicted ATPase IL1995 99 COG1485 COG1485, Predicted ATPase General function prediction only 56460723 Common - hypothetical protein IL1620 5 None None None 56461633 Nonpathogen - Predicted glycosyltransferase IL2533 1 None None None 56460360 Common - hypothetical protein IL1252 17 COG5591 COG5591, Uncharacterized conserved protein Function unknown 56461101 Common motX Na+-type flagellar protein, contains TPR repeats IL2001 28 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 56459851 Common recA RecA recombinase IL0742 214 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 56459148 Common purK Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) IL0036 193 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 56461510 Nonpathogen - hypothetical protein IL2410 1 None None None 56460269 Common relE Cytotoxic translational repressor of toxin-antitoxin stability system IL1161 30 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 56461277 Common - Outer membrane protein IL2177 117 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 56461597 Common - Uncharacterized conserved secreted or membrane protein IL2497 11 None None None 56461680 Common - Outer membrane protein IL2580 97 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 56459328 Common - L-allo-threonine aldolase IL0217 90 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 56460381 Common proQ putative solute/DNA competence effector IL1273 33 COG3109 ProQ, Activator of osmoprotectant transporter ProP Signal transduction mechanisms 56460801 Common lig NAD-dependent DNA ligase IL1700 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 56459133 Common - Zn-finger domain associated with topoisomerase type I IL0021 107 COG0551 TopA, Zn-finger domain associated with topoisomerase type I DNA replication, recombination, and repair 56459376 Common ubiC 4-hydroxybenzoate synthetase IL0265 32 COG3161 UbiC, 4-hydroxybenzoate synthetase (chorismate lyase) Coenzyme metabolism 56460375 Common - Predicted carboxypeptidase, Zn dependent IL1267 26 COG2866 COG2866, Predicted carboxypeptidase Amino acid transport and metabolism 56460531 Nonpathogen - hypothetical protein IL1423 5 None None None 56459530 Common sspA Glutathione S-transferase related protein IL0419 80 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 56460813 Common sUI1 translation initiation factor Sui1 IL1712 84 COG0023 SUI1, Translation initiation factor 1 (eIF-1/SUI1) and related proteins Translation, ribosomal structure and biogenesis 56460056 Common rlpB Rare lipoprotein B IL0948 39 COG2980 RlpB, Rare lipoprotein B Cell envelope biogenesis, outer membrane 56459777 Common lrp Lrp IL0668 159 COG1522 Lrp, Transcriptional regulators Transcription 56459679 Common pgi Glucose-6-phosphate isomerase IL0570 196 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 56461364 Common - ABC-type transport system, ATPase component IL2264 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 56459865 Common - hypothetical protein IL0756 28 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 56460969 Common ribAB 3,4-dihydroxy-2-butanone 4-phosphate synthase IL1869 229 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 56459889 Nonpathogen - hypothetical protein IL0780 1 None None None 56460930 Nonpathogen - hypothetical protein IL1830 1 None None None 56461664 Common - Il-IS_1, transposase IL2563.1 105 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 56459117 Common glyS glycyl-tRNA synthetase subunit beta IL0005 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 56460112 Common clpX ATP-dependent protease ATP-binding subunit IL1004 225 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 56461464 Common - Ppx/GppA phosphatase family protein IL2364 180 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 56460474 Common grxA glutaredoxin 1 IL1366 33 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 56461377 Common - Probable lysine 2,3-aminomutase IL2277 126 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 56459658 Common - Predicted pyridoxal phosphate-dependent enzyme IL0549 190 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 56460866 Common - Sugar nucleotide epimerase IL1765 106 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 56461108 Common - Secreted protein of porin family IL2008 23 None None None 56460453 Common - hypothetical protein IL1345 56 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 56459363 Common - Uncharacterized secreted protein of SCO1/SenC/PrrC family IL0252 96 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 56459807 Common - hypothetical protein IL0698 13 None None None 56460643 Common pqqL Peptidase, M16 family IL1537 198 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 56459138 Common - Predicted permease IL0026 114 COG2962 RarD, Predicted permeases General function prediction only 56459767 Common - Integral membrane protein IL0658 79 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 56460945 Common adk Adenylate kinase IL1845 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 56459559 Common - hypothetical protein IL0448 44 COG4582 COG4582, Uncharacterized protein conserved in bacteria Function unknown 56461345 Common hemL Glutamate-1-semialdehyde aminotransferase IL2245 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 56460364 Common - hypothetical protein IL1256 15 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 56459400 Nonpathogen - hypothetical protein IL0289 2 None None None 56459734 Common - Conserved protein containing metal-dependent amidohydrolase family domain IL0625 7 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 56459523 Common - hypothetical protein IL0412 22 COG3105 COG3105, Uncharacterized protein conserved in bacteria Function unknown 56459302 Common - Predicted lipid carrier protein IL0191 34 COG3154 COG3154, Putative lipid carrier protein Lipid metabolism 56459156 Common - Amidohydrolase family enzyme IL0044 55 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 56459651 Common rffH DTDP-glucose pyrophosphorylase IL0542 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 56461380 Common groL Chaperonin GroEL (HSP60 family) IL2280 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 56460395 Common fabA 3-hydroxydecanoyl-(acyl carrier protein) dehydratase IL1287 81 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism