Geobacillus kaustophilus HTA426, complete genome NC_006510 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 56418547 Common - 2-deoxy-scyllo-inosose synthase20kDa subunit GK0012 98 COG0311 PDX2, Predicted glutamine amidotransferase involved in pyridoxine biosynthesis Coenzyme metabolism 56421024 Common - cytidine deaminase GK2489 122 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 56418860 Common - hypothetical protein GK0325 37 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 56418845 Common - lantibiotic ABC transporter (permease) GK0310 6 COG4200 COG4200, Uncharacterized protein conserved in bacteria Function unknown 56420050 Common - hypothetical protein GK1515 45 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 56421987 Common - sodium:proline symporter (osmoregulation) GK3452 182 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 56420207 Common - hypothetical protein GK1672 78 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 56421461 Common - hypothetical protein GK2926 24 COG2155 COG2155, Uncharacterized conserved protein Function unknown 56418919 Common hutP anti-terminator HutP GK0384 2 None None None 56419487 Common - transaminase GK0952 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 56421625 Common - hypothetical protein GK3090 8 None None None 56421243 Nonpathogen - hypothetical protein GK2708 1 COG2433 COG2433, Uncharacterized conserved protein Function unknown 56418666 Common rpsM 30S ribosomal protein S13 GK0131 246 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 56419995 Common - iron(III) dicitrate ABC transporter (permease) GK1460 183 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 56419755 Common fliG flagellar motor switch protein G GK1220 125 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 56421194 Common - ketol-acid reductoisomerase GK2659 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 56421250 Nonpathogen - hypothetical protein GK2715 1 COG3326 COG3326, Predicted membrane protein Function unknown 56419234 Common - hypothetical protein GK0699 2 None None None 56420362 Common - nitrate reductase delta subunit GK1827 49 COG2180 NarJ, Nitrate reductase delta subunit Energy production and conversion 56421499 Common - homoserine dehydrogenase GK2964 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 56421419 Common - hypothetical protein GK2884 78 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 56420690 Nonpathogen - hypothetical protein GK2155 1 None None None 56419367 Common - diadenosine tetraphosphatase GK0832 96 COG0639 ApaH, Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Signal transduction mechanisms 56419354 Common - adaptor protein GK0819 13 COG4862 MecA, Negative regulator of genetic competence, sporulation and motility Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Cell motility and secretion 56419866 Common - hypothetical protein GK1331 14 COG4224 COG4224, Uncharacterized protein conserved in bacteria Function unknown 56421219 Nonpathogen - hypothetical protein GK2684 1 None None None 56419360 Common - hypothetical protein GK0825 71 COG2346 COG2346, Truncated hemoglobins General function prediction only 56420988 Common - hypothetical protein GK2453 3 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 56421972 Common - phosphate ABC transporter (permease) GK3437 225 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 56418965 Common - hypothetical protein GK0430 3 None None None 56420131 Common - transcriptional regulator (TetR/AcrR family) GK1596 98 COG1309 AcrR, Transcriptional regulator Transcription 56419025 Nonpathogen - hypothetical protein GK0490 1 None None None 56418960 Common - hypothetical protein GK0425 5 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 56421441 Common - hypothetical protein GK2906 127 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 56420463 Common ureF urease accessory protein GK1928 44 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 56418973 Common - transcriptional activator GK0438 137 COG0789 SoxR, Predicted transcriptional regulators Transcription 56421747 Common - 6-phospho-beta-glucosidase GK3212 54 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 56420618 Common - cytochrome bd-type ubiquinol oxidase subunit II GK2083 12 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 56420367 Common - two-component sensor histidine kinase GK1832 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 56420541 Common - hypothetical protein GK2006 102 COG0579 COG0579, Predicted dehydrogenase General function prediction only 56421207 Common sdhA succinate dehydrogenase flavoprotein subunit GK2672 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 56420316 Common - hypothetical protein GK1781 11 None None None 56419211 Common - isocitrate lyase GK0676 128 COG2224 AceA, Isocitrate lyase Energy production and conversion 56421933 Common - iron-sulfur oxidoreductase GK3398 107 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 56420861 Common - hypothetical protein GK2326 3 COG4918 COG4918, Uncharacterized protein conserved in bacteria Function unknown 56421727 Common - hypothetical protein GK3192 4 None None None 56419930 Common - hypothetical protein GK1395 2 None None None 56419613 Common - cell-division protein GK1078 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 56421743 Common - two-component response regulator GK3208 224 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 56420146 Nonpathogen - hypothetical protein GK1611 1 None None None 56420160 Common - spore germination protein GK1625 15 None None None 56419750 Common - transcriptional repressor CodY GK1215 20 COG4465 CodY, Pleiotropic transcriptional repressor Transcription 56421255 Common - hypothetical protein GK2720 15 None None None 56421321 Common - hypothetical protein GK2786 15 COG0827 COG0827, Adenine-specific DNA methylase DNA replication, recombination, and repair 56418936 Common - hypothetical protein GK0401 190 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 56419394 Common - thioredoxin GK0859 147 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 56420103 Common - hypothetical protein GK1568 77 COG2928 COG2928, Uncharacterized conserved protein Function unknown 56421607 Common - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase GK3072 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 56421381 Common - hypothetical protein GK2846 29 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 56421731 Common - iron-sulfur binding protein GK3196 17 COG3543 COG3543, Uncharacterized conserved protein Function unknown 56418941 Common - hypothetical protein GK0406 67 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 56420045 Common - phosphomethylpyrimidine kinase GK1510 217 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 56421844 Common - serine acetyltransferase GK3309 212 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 56420276 Common - short chain-specific acyl-CoA dehydrogenase GK1741 143 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 56420791 Common - hypothetical protein GK2256 9 None None None 56418903 Common - hypothetical protein GK0368 23 COG1714 COG1714, Predicted membrane protein/domain Function unknown 56420699 Nonpathogen - hypothetical protein GK2164 1 None None None 56420623 Common - hypothetical protein GK2088 218 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 56421853 Common - hypothetical protein GK3318 93 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 56421376 Common - hypothetical protein GK2841 145 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 56419738 Common - type I signal peptidase GK1203 201 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 56420098 Common - hypothetical protein GK1563 4 None None None 56421424 Common - 1-pyrroline-5-carboxylate dehydrogenase GK2889 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 56419650 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase GK1115 212 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 56421148 Common minD ATPase involved in chromosome partitioning GK2613 164 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 56420548 Common - glycolate oxidase iron-sulfur subunit GK2013 179 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 56420568 Nonpathogen - hypothetical protein GK2033 1 None None None 56418914 Common - carbon monoxide dehydrogenase large subunit GK0379 115 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 56419582 Nonpathogen - hypothetical protein GK1047 1 None None None 56418895 Common - nucleoside-diphosphate-sugar pyrophosphorylase GK0360 229 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 56421004 Common - transcriptional regulator (Fur family) GK2469 188 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 56421318 Common - hypothetical protein GK2783 24 COG3255 COG3255, Putative sterol carrier protein Lipid metabolism 56421924 Common - CTP synthetase GK3389 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 56420404 Common - hypothetical protein GK1869 8 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 56419626 Common - hypothetical protein GK1091 46 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 56419939 Nonpathogen - hypothetical protein GK1404 2 None None None 56420059 Nonpathogen - hypothetical protein GK1524 1 None None None 56419117 Common - potassium transporter (Trk family) GK0582 96 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 56418910 Common - L-lysine dehydrogenase GK0375 64 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 56420788 Common - negative regulator of sigma-X activity GK2253 2 None None None 56421229 Common - hypothetical protein GK2694 89 COG1796 POL4, DNA polymerase IV (family X) DNA replication, recombination, and repair 56419659 Common ftsA cell division protein (septum formation) GK1124 185 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 56419610 Common - phosphate starvation-induced protein GK1075 191 COG1875 COG1875, Predicted ATPase related to phosphate starvation-inducible protein PhoH Signal transduction mechanisms 56418954 Common - protein-tyrosine phosphatase GK0419 141 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 56419512 Common - coenzyme PQQ synthesis GK0977 113 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 56419351 Common - hypothetical protein GK0816 2 None None None 56419452 Nonpathogen - hypothetical protein GK0917 1 None None None 56420324 Nonpathogen - hypothetical protein GK1789 1 None None None 56421816 Common - hypothetical protein GK3281 7 COG2268 COG2268, Uncharacterized protein conserved in bacteria Function unknown 56420400 Common - nitrate/nitrite transporter GK1865 117 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 56419804 Common - polynucleotide phosphorylase/polyadenylase GK1269 241 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 56421548 Nonpathogen - hypothetical protein GK3013 1 None None None 56420723 Common - hypothetical protein GK2188 2 None None None 56421042 Common - coproporphyrinogen III oxidase GK2507 218 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 56420305 Common - hypothetical protein GK1770 100 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 56420560 Common - transposase GK2025 107 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 56420576 Common - ring-oxidation complex protein 3 (phenylacetic acid catabolism) GK2041 104 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 56421799 Common - hypothetical protein GK3264 3 None None None 56418728 Common - ferrichrome ABC transporter (ferrichrome-binding protein) GK0193 70 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 56418929 Common - hypothetical protein GK0394 94 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 56421831 Common - UDP-glucose 4-epimerase GK3296 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 56420249 Common - transcriptional repressor of sporulation and degradative enzyme production GK1714 60 COG2808 PaiB, Transcriptional regulator Transcription 56419775 Common - hypothetical protein GK1240 154 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 56420750 Common hbs DNA-binding protein HU (DNA-binding protein II) GK2215 214 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 56420894 Common - transposase GK2359 32 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 56421772 Nonpathogen - hypothetical protein GK3237 2 None None None 56420370 Common - hypothetical protein GK1835 124 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 56420011 Common - hypothetical protein GK1476 9 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 56419420 Common - hypothetical protein GK0885 26 COG4694 COG4694, Uncharacterized protein conserved in bacteria Function unknown 56420914 Common - dihydrolipoamide dehydrogenase GK2379 241 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 56421804 Common - UTP-glucose-1-phosphate uridylyltransferase (uridine diphosphoglucose pyrophosphorylase) (general stress protein 33) GK3269 234 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 56420845 Common - anti-sigma F factor antagonist (stage II sporulation protein AA) GK2310 71 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 56419554 Common - hypothetical protein GK1019 2 None None None 56419596 Common - dihydrolipoamide dehydrogenase GK1061 246 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 56418576 Common - translation initiation inhibitor GK0041 195 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 56421633 Common - pimeloyl-CoA synthesis (biotin biosynthesis) GK3098 73 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 56419344 Common trpS tryptophanyl-tRNA synthetase GK0809 232 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 56421541 Common - acetyl-CoA dehydrogenase GK3006 163 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 56421728 Common - hypothetical protein GK3193 23 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 56419130 Common - cassette chromosome recombinase B GK0595 75 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 56419266 Common - alcohol dehydrogenase GK0731 214 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 56421602 Common - NTP pyrophosphohydrolase including oxidative damage repair enzyme GK3067 121 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 56419981 Common - hypothetical protein GK1446 7 COG4915 XpaC, 5-bromo-4-chloroindolyl phosphate hydrolysis protein General function prediction only 56421416 Common - cation efflux transporter GK2881 220 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 56420557 Common - hypothetical protein GK2022 207 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 56420424 Common iolB myo-inositol catabolism protein GK1889 54 COG3718 IolB, Uncharacterized enzyme involved in inositol metabolism Carbohydrate transport and metabolism 56420606 Common - hypothetical protein GK2071 88 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 56420650 Common - transcriptional regulator GK2115 131 COG1609 PurR, Transcriptional regulators Transcription 56418837 Common - hypothetical protein GK0302 18 None None None 56418672 Common - cobalt transporter system (permease) GK0137 80 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 56421264 Nonpathogen - hypothetical protein GK2729 1 None None None 56418599 Common hslO Hsp33-like chaperonin GK0064 138 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 56418588 Common - hypothetical protein GK0053 15 None None None 56420084 Common - hypothetical protein GK1549 77 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 56419407 Common - hypothetical protein GK0872 3 COG2327 WcaK, Uncharacterized conserved protein Function unknown 56421301 Common - molybdopterin precursor biosynthesis GK2766 189 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 56419063 Common - phage-terminase large subunit GK0528 47 COG4626 COG4626, Phage terminase-like protein, large subunit General function prediction only 56420036 Common - hypothetical protein GK1501 115 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 56419678 Nonpathogen - hypothetical protein GK1143 1 None None None 56419339 Common - 3-oxoacyl-(acyl carrier protein) synthase III GK0804 225 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 56419072 Common - hypothetical protein GK0537 2 None None None 56419165 Common - hypothetical protein GK0630 6 None None None 56421898 Common - F0F1 ATP synthase subunit C GK3363 26 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 56419479 Common - two-component sensor histidine kinase GK0944 223 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 56419912 Nonpathogen - hypothetical protein GK1377 1 None None None 56421790 Common - N-acetylmuramoyl-L-alanine amidase GK3255 181 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 56420289 Common - ABC transporter GK1754 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 56419833 Common - hypothetical protein GK1298 81 COG1692 COG1692, Uncharacterized protein conserved in bacteria Function unknown 56421528 Common - cysteine desulfurase GK2993 238 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 56420037 Common - hypothetical protein GK1502 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 56419009 Common - hypothetical protein GK0474 39 COG3694 COG3694, ABC-type uncharacterized transport system, permease component General function prediction only 56419004 Common - dipeptide ABC transporter (permease) GK0469 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 56419469 Common - small acid-soluble spore protein (minor alpha/beta-type SASP) GK0934 9 None None None 56418805 Common - hypothetical protein GK0270 2 None None None 56419852 Common - acyl-CoA transferase/carnitine dehydratase GK1317 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 56420773 Common - spore coat peptide assembly protein GK2238 9 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 56420472 Common - ABC transporter (substrate-binding protein) GK1937 140 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 56420475 Common - hypothetical protein GK1940 47 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 56421514 Common - branched-chain amino acid ABC transporter (permease) GK2979 174 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 56421748 Common - transcriptional regulator GK3213 59 COG1737 RpiR, Transcriptional regulators Transcription 56421123 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase GK2588 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 56420468 Common - ABC transporter (ATP-binding protein) GK1933 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 56418700 Common - hypothetical protein GK0165 19 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 56418985 Common - hypothetical protein GK0450 3 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 56421181 Common - negative effector of the concentration of HemA GK2646 14 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 56421575 Nonpathogen - hypothetical protein GK3040 2 None None None 56419792 Common proS prolyl-tRNA synthetase GK1257 244 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 56420707 Common - aspartate aminotransferase GK2172 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 56421596 Common - RNA polymerase factor sigma-54 GK3061 144 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 56420253 Common - hypothetical protein GK1718 15 None None None 56419385 Common - hypothetical protein GK0850 2 None None None 56420396 Nonpathogen - hypothetical protein GK1861 1 None None None 56421349 Common - hypothetical protein GK2814 3 COG4768 COG4768, Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain General function prediction only 56419816 Common spoIIIE DNA translocase (stage III sporulation protein E) GK1281 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 56421143 Common rpmA 50S ribosomal protein L27 GK2608 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 56421200 Common - hypothetical protein GK2665 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 56419157 Common - transcriptional regulator TenI GK0622 67 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 56421765 Common - ribokinase GK3230 218 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 56421053 Common comER late competence protein ComER GK2518 152 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 56418822 Nonpathogen - hypothetical protein GK0287 1 None None None 56421141 Common obgE GTPase ObgE GK2606 249 COG0536 Obg, Predicted GTPase General function prediction only 56421356 Nonpathogen - hypothetical protein GK2821 3 COG5584 COG5584, Predicted small secreted protein Function unknown 56419041 Common - bacteriophage-related protein GK0506 3 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 56420554 Nonpathogen - hypothetical protein GK2019 1 None None None 56419790 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase GK1255 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 56420965 Nonpathogen - hypothetical protein GK2430 1 COG4940 ComGF, Competence protein ComGF Intracellular trafficking and secretion 56419052 Nonpathogen - phage-like element PBSX protein GK0517 1 None None None 56418665 Common rpmJ 50S ribosomal protein L36 GK0130 136 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 56418709 Common - hypothetical protein GK0174 18 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 56421189 Common - hypothetical protein GK2654 5 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 56419986 Nonpathogen - hypothetical protein GK1451 1 None None None 56421210 Common uvrC excinuclease ABC subunit C GK2675 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 56419900 Common - formiminoglutamase GK1365 60 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 56421534 Common - ABC transporter (ATP-binding protein) GK2999 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 56420597 Common - hypothetical protein GK2062 14 COG3239 DesA, Fatty acid desaturase Lipid metabolism 56420535 Common - aldehyde dehydrogenase GK2000 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 56421805 Common - unknwon conserved protein GK3270 34 COG2152 COG2152, Predicted glycosylase Carbohydrate transport and metabolism 56420165 Common - ABC transporter (ATP-binding protein) GK1630 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 56420255 Nonpathogen - hypothetical protein GK1720 6 None None None 56421278 Common - transcriptional regulator GK2743 77 COG2186 FadR, Transcriptional regulators Transcription 56421342 Common - acetoin utilization protein GK2807 8 None None None 56421490 Nonpathogen - hypothetical protein GK2955 1 COG5416 COG5416, Uncharacterized integral membrane protein Function unknown 56419274 Common - transcriptional repressor of sporulation and degradative enzyme production GK0739 61 COG2808 PaiB, Transcriptional regulator Transcription 56419411 Nonpathogen - hypothetical protein GK0876 1 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 56419068 Nonpathogen - hypothetical protein GK0533 1 None None None 56420174 Nonpathogen - hypothetical protein GK1639 1 None None None 56418590 Common - cell-division initiation protein GK0055 3 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 56422020 Common - hypothetical protein GK3485 28 COG4481 COG4481, Uncharacterized protein conserved in bacteria Function unknown 56421941 Common - penicillin-binding protein GK3406 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 56418872 Common - hypothetical protein GK0337 21 COG4323 COG4323, Predicted membrane protein Function unknown 56421035 Common - hypothetical protein GK2500 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 56420331 Common - cobyrinic acid a,c-diamide synthase GK1796 137 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 56421965 Common - glycyl-tRNA synthetase GK3430 86 COG0423 GRS1, Glycyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 56418647 Common rpsC 30S ribosomal protein S3 GK0112 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 56421591 Common tpi triose-phosphate isomerase GK3056 220 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 56420061 Common - hypothetical protein GK1526 51 COG3180 AbrB, Putative ammonia monooxygenase General function prediction only 56421573 Common - hypothetical protein GK3038 54 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 56420456 Common - maltose transacetylase (maltose O-acetyltransferase) GK1921 192 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 56419530 Common ptsH phosphocarrier protein (histidine-containing protein) GK0995 101 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 56420684 Common - UDP-glucose 4-epimerase GK2149 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 56419563 Common - acyl-CoA dehydrogenase GK1028 148 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 56421651 Common - transposase GK3116 28 COG5421 COG5421, Transposase DNA replication, recombination, and repair 56420009 Nonpathogen - acyl carrier protein (ACP) GK1474 1 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 56420946 Common - Xaa-Pro dipeptidase GK2411 248 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 56420668 Common - hypothetical protein GK2133 23 COG5658 COG5658, Predicted integral membrane protein Function unknown 56420118 Common - hypothetical protein GK1583 201 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 56421058 Common - hypothetical protein GK2523 104 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 56419609 Common - hypothetical protein GK1074 8 None None None 56419945 Common - sulfite reductase hemoprotein beta-component GK1410 149 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 56419050 Common - hypothetical protein GK0515 9 COG4508 COG4508, Uncharacterized protein conserved in bacteria Function unknown 56421389 Common - dipeptidyl aminopeptidase/acylaminoacyl-peptidase GK2854 49 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 56421454 Nonpathogen - hypothetical protein GK2919 1 None None None 56418998 Common - adenine glycosylase GK0463 236 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 56419455 Common - hypothetical protein GK0920 2 None None None 56419820 Common - sugar ABC transporter (permease) GK1285 144 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 56418778 Common - hypothetical protein GK0243 3 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 56421567 Common - dihydrodipicolinate synthase GK3032 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 56419891 Common - cold shock protein GK1356 182 COG1278 CspC, Cold shock proteins Transcription 56421069 Common - proton/sodium:glutamate symporter GK2534 163 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 56419766 Common fliY flagellar motor switch protein GK1231 129 COG1776 CheC, Chemotaxis protein CheC, inhibitor of MCP methylation Cell motility and secretion / Signal transduction mechanisms 56418712 Common - hypothetical protein GK0177 153 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 56420580 Common - phenylacetyl-CoA ligase (phenylacetic acid catabolism) GK2045 130 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 56421336 Common - two-component sensor histidine kinase GK2801 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 56419022 Common - hypothetical protein GK0487 71 COG2718 COG2718, Uncharacterized conserved protein Function unknown 56419883 Nonpathogen - hypothetical protein GK1348 1 None None None 56419225 Common gerPA spore germination protein GK0690 2 None None None 56420938 Common spoIIIAF stage III sporulation protein AF GK2403 3 None None None 56420850 Common xerD site-specific tyrosine recombinase XerD GK2315 234 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 56421688 Common - attenuator role for lytABC and lytR expression GK3153 64 COG1316 LytR, Transcriptional regulator Transcription 56419541 Common - transposase of IS5377-like element GK1006 23 COG3385 COG3385, FOG: Transposase and inactivated derivatives DNA replication, recombination, and repair 56419797 Common - hypothetical protein GK1262 25 COG1358 RPL8A, Ribosomal protein HS6-type (S12/L30/L7a) Translation, ribosomal structure and biogenesis 56421788 Common - hypothetical protein GK3253 7 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 56421153 Common radC DNA repair protein RadC GK2618 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 56419631 Common - hypothetical protein GK1096 11 COG4471 COG4471, Uncharacterized protein conserved in bacteria Function unknown 56419137 Nonpathogen - hypothetical protein GK0602 1 None None None 56419713 Common - ribulose-phosphate 3-epimerase GK1178 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 56421082 Common greA transcription elongation factor GreA GK2547 203 COG0782 GreA, Transcription elongation factor Transcription 56421276 Common - acetyl-CoA carboxylase carboxyltransferase subunit alpha GK2741 178 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 56419876 Common - hypothetical protein GK1341 6 COG4846 CcdC, Membrane protein involved in cytochrome C biogenesis Posttranslational modification, protein turnover, chaperones 56420002 Nonpathogen - hypothetical protein GK1467 1 None None None 56419829 Common - competence damage-inducible protein A GK1294 212 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 56421677 Common fliC flagellar protein GK3142 118 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 56420747 Common gerCA heptaprenyl diphosphate synthasecomponent I (spore germination protein C1) GK2212 3 None None None 56420880 Nonpathogen - hypothetical protein GK2345 1 None None None 56421584 Common - thermostable carboxylesterase GK3049 62 COG2272 PnbA, Carboxylesterase type B Lipid metabolism 56420908 Common - two-component sensor histidine kinase GK2373 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 56421674 Common - anti-sigma factor repressor of sigma-D-dependent transcription (negative regulator of flagellin synthesis) (anti-sigma-D factor) GK3139 4 COG2747 FlgM, Negative regulator of flagellin synthesis (anti-sigma28 factor) Transcription / Cell motility and secretion / Intracellular trafficking and secretion 56419079 Nonpathogen - hypothetical protein GK0544 1 None None None 56420681 Common - heat shock protein GK2146 157 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 56420230 Common - transposase GK1695 17 COG5421 COG5421, Transposase DNA replication, recombination, and repair 56420321 Common - hypothetical protein GK1786 2 None None None 56421647 Nonpathogen fliT flagellar protein GK3112 3 None None None 56420857 Common - cyanate transporter GK2322 79 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 56419059 Nonpathogen - hypothetical protein GK0524 2 None None None 56419757 Common fliI flagellum-specific ATP synthase GK1222 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 56420495 Common - hypothetical protein GK1960 10 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 56419784 Common rpsB 30S ribosomal protein S2 GK1249 248 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 56421266 Common - two-component sensor histidine kinase (phosphate regulation) GK2731 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 56418677 Common - germination-specific N-acetylmuramoyl-L-alanine amidase (cell wall hydrolase) (autolysin) GK0142 145 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 56419924 Common - hypothetical protein GK1389 3 None None None 56421078 Common - S-adenosylmethionine(SAM)-dependent methyltransferase GK2543 83 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 56421399 Common - hypothetical protein GK2864 187 COG0759 COG0759, Uncharacterized conserved protein Function unknown 56418844 Nonpathogen - lantibiotic biosynthesis protein GK0309 1 None None None 56420834 Common - hypothetical protein GK2299 12 COG4086 COG4086, Predicted secreted protein Function unknown 56419186 Nonpathogen - hypothetical protein GK0651 1 None None None 56420444 Common araG ABC transporter (ATP-binding protein) GK1909 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 56420967 Common - hypothetical protein GK2432 3 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 56418613 Common - ATP-dependent Clp protease ATPase subunit GK0078 220 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 56419281 Nonpathogen - hypothetical protein GK0746 1 None None None 56422031 Common - OxaA-like protein precursor GK3496 211 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 56419462 Common - acetyltransferase (GNAT family) GK0927 75 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 56421884 Common - NADH dehydrogenase subunit J GK3349 154 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 56420659 Common - hypothetical protein GK2124 2 None None None 56421610 Common hisD histidinol dehydrogenase GK3075 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 56418546 Common - pyridoxine biosynthesis protein GK0011 87 COG0214 SNZ1, Pyridoxine biosynthesis enzyme Coenzyme metabolism 56421087 Common - hypothetical protein GK2552 186 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 56421684 Common - hypothetical protein GK3149 54 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 56420841 Common - stage V sporulation protein AB GK2306 4 None None None 56420643 Common - transposase GK2108 66 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 56422007 Common - hypothetical protein GK3472 8 COG4863 COG4863, Uncharacterized protein conserved in bacteria Function unknown 56419884 Common - hypothetical protein GK1349 26 COG1963 COG1963, Uncharacterized protein conserved in bacteria Function unknown 56419937 Nonpathogen - hypothetical protein GK1402 1 None None None 56421106 Common - hypothetical protein GK2571 209 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 56420121 Nonpathogen - hypothetical protein GK1586 1 None None None 56420488 Common - transcriptional regulator GK1953 171 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 56419567 Common - hypothetical protein GK1032 60 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 56419514 Common - semialdehyde dehydrogenase GK0979 47 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 56421051 Common comEB late competence protein (DNA binding and uptake) GK2516 94 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 56418633 Common rpoB DNA-directed RNA polymerase subunit beta GK0098 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 56421904 Common glyA serine hydroxymethyltransferase GK3369 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 56418625 Common rpmG 50S ribosomal protein L33 GK0090 60 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 56421992 Common qoxC cytochrome aa3 quinol oxidase subunit III GK3457 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 56418568 Common - hypothetical protein GK0033 34 COG3583 COG3583, Uncharacterized protein conserved in bacteria Function unknown 56421665 Nonpathogen - hypothetical protein GK3130 2 None None None 56418734 Common - aldehyde dehydrogenase GK0199 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 56421527 Common - nitrogen fixation protein (NifU protein) GK2992 175 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 56419007 Common - ABC transporter (ATP-binding protein) GK0472 249 COG4586 COG4586, ABC-type uncharacterized transport system, ATPase component General function prediction only 56420804 Common - amino acid transporter GK2269 175 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 56421751 Common - pyruvate dehydrogenase E1 (lipoamide) beta subunit GK3216 221 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 56418682 Common - KinB signaling pathway activation protein GK0147 3 None None None 56421114 Common - adenine phosphoribosyltransferase GK2579 181 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 56418836 Common - transposase GK0301 27 COG5421 COG5421, Transposase DNA replication, recombination, and repair 56421015 Common - cytochrome c GK2480 6 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 56421708 Nonpathogen - hypothetical protein GK3173 1 None None None 56419628 Common - hypothetical protein GK1093 3 None None None 56421914 Nonpathogen - hypothetical protein GK3379 1 None None None 56419742 Common - hypothetical protein GK1207 113 COG2257 COG2257, Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB Function unknown 56419680 Common lspA lipoprotein signal peptidase GK1145 131 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 56419018 Common - hypothetical protein GK0483 16 None None None 56419195 Common - hypothetical protein GK0660 15 None None None 56419108 Common - alkaline phosphatase GK0573 156 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 56420266 Nonpathogen - hypothetical protein GK1731 1 None None None 56419376 Common - glycosyltransferase GK0841 212 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 56419773 Common flhA flagellar biosynthesis protein A GK1238 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 56418803 Common - phosphoribosylamine--glycine ligase GK0268 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 56418771 Common - hypothetical protein GK0236 208 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 56419573 Nonpathogen - hypothetical protein GK1038 2 None None None 56421286 Common - Xaa-Pro dipeptidase GK2751 248 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 56420762 Common cmk cytidylate kinase GK2227 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 56421820 Nonpathogen - hypothetical protein GK3285 1 None None None 56418813 Common - hypothetical protein GK0278 126 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 56420183 Common - ppGpp-regulated growth inhibitor (ChpA/MazF) GK1648 52 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 56421233 Common - hypothetical protein GK2698 100 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 56421507 Common - hypothetical protein GK2972 11 COG4470 COG4470, Uncharacterized protein conserved in bacteria Function unknown 56418593 Common - hypothetical protein GK0058 4 COG2304 COG2304, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 56420336 Common cbiD cobalt-precorrin-6A synthase GK1801 95 COG1903 CbiD, Cobalamin biosynthesis protein CbiD Coenzyme metabolism 56420275 Common - spermidine synthase(putrescine aminopropyltransferase) GK1740 121 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 56420950 Common - hypothetical protein GK2415 25 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 56419293 Common - nitric oxide reductase cytochrome b subunit GK0758 75 COG3256 NorB, Nitric oxide reductase large subunit Inorganic ion transport and metabolism 56421227 Common - hypothetical protein GK2692 4 COG3766 COG3766, Predicted membrane protein Function unknown 56419694 Common - hypothetical protein GK1159 3 None None None 56421136 Common - L-aspartate oxidase GK2601 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 56421444 Common - hypothetical protein GK2909 3 None None None 56419860 Common - aluminum resistance protein GK1325 34 COG4100 COG4100, Cystathionine beta-lyase family protein involved in aluminum resistance Inorganic ion transport and metabolism 56421957 Common - stage II sporulation protein AA (anti-anti-sigma factor,antagonist of SpoIIAB) GK3422 33 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 56420740 Common aroH chorismate mutase GK2205 38 COG4401 AroH, Chorismate mutase Amino acid transport and metabolism 56421390 Common - nitrate/sulfonate/taurine/bicarbonate ABC transporter (substrate binding protein) GK2855 62 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 56420372 Common - hypothetical protein GK1837 87 COG0701 COG0701, Predicted permeases General function prediction only 56421617 Common - HPr kinase/phosphorylase GK3082 71 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 56420116 Common - D-alanyl-D-alanine carboxypeptidase GK1581 37 COG1876 VanY, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 56421426 Nonpathogen - hypothetical protein GK2891 1 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 56421366 Common - Xaa-His dipeptidase GK2831 181 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 56421293 Common - hypothetical protein GK2758 2 None None None 56419148 Common - hypothetical protein GK0613 27 COG2879 COG2879, Uncharacterized small protein Function unknown 56421192 Common - 3-isopropylmalate dehydrogenase GK2657 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 56419556 Nonpathogen - hypothetical protein GK1021 1 None None None 56419539 Common - hypothetical protein GK1004 5 None None None 56419905 Common - large conductance mechanosensitive channel protein GK1370 144 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 56418752 Common - transcriptional regulator GK0217 140 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 56421910 Common - hypothetical protein GK3375 236 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 56419313 Common - hypothetical protein GK0778 18 None None None 56419094 Common - two-component sensor histidine kinase GK0559 215 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 56419141 Nonpathogen - hypothetical protein GK0606 1 None None None 56421717 Common - 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase bifunctional periplasmic precursor protein GK3182 129 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 56418881 Common - type I restriction-modification system R subunit (endonuclease) GK0346 114 COG4096 HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 56420390 Common - transcriptional regulator (GntR family) GK1855 129 COG2188 PhnF, Transcriptional regulators Transcription 56419869 Common - hypothetical protein GK1334 8 COG3763 COG3763, Uncharacterized protein conserved in bacteria Function unknown 56419038 Nonpathogen - hypothetical protein GK0503 1 None None None 56419964 Common - hypothetical protein GK1429 170 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 56418654 Common rpsN 30S ribosomal protein S14 GK0119 199 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 56420871 Nonpathogen - hypothetical protein GK2336 6 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 56420901 Nonpathogen - hypothetical protein GK2366 1 None None None 56419369 Common - enoyl-(acyl carrier protein) reductase GK0834 232 COG0623 FabI, Enoyl- acyl-carrier-protein 56421130 Common - hypothetical protein GK2595 2 None None None 56421401 Common - hypothetical protein GK2866 119 COG3391 COG3391, Uncharacterized conserved protein Function unknown 56418580 Common rplY 50S ribosomal protein L25/general stress protein Ctc GK0045 175 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 56418723 Common rocD ornithine--oxo-acid transaminase GK0188 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 56421861 Common - capsular polysaccharide biosynthesis protein GK3326 164 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 56418744 Common - N-acetylmuramoyl-L-alanine amidase GK0209 180 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 56420433 Common - myo-inositol 2-dehydrogenase GK1898 142 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 56419725 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase GK1190 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 56418796 Common - phosphoribosylformylglycinamidine synthase subunit PurS GK0261 113 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 56419525 Common - transcription antiterminator GK0990 30 COG3711 BglG, Transcriptional antiterminator Transcription 56421656 Common - nucleoside-diphosphate-sugar pyrophosphorylase GK3121 222 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 56420505 Nonpathogen - hypothetical protein GK1970 14 COG2768 COG2768, Uncharacterized Fe-S center protein General function prediction only 56420977 Common glcK glucokinase GK2442 168 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 56420543 Common - polyamine ABC transporter (permease) GK2008 209 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 56420806 Nonpathogen - hypothetical protein GK2271 1 COG4389 COG4389, Site-specific recombinase DNA replication, recombination, and repair 56421620 Common uvrA excinuclease ABC subunit A GK3085 245 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 56421701 Common - hypothetical protein GK3166 192 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 56421537 Common - hypothetical protein GK3002 5 COG1658 COG1658, Small primase-like proteins (Toprim domain) DNA replication, recombination, and repair 56421156 Nonpathogen - hypothetical protein GK2621 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 56420751 Nonpathogen - hypothetical protein GK2216 1 None None None 56419254 Nonpathogen - circularin A precursor GK0719 2 None None None 56418698 Common - transposase GK0163 16 None None None 56419190 Nonpathogen - hypothetical protein GK0655 1 None None None 56418605 Common - dihydroneopterin aldolase GK0070 71 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 56419701 Common - hypothetical protein GK1166 33 COG2052 COG2052, Uncharacterized protein conserved in bacteria Function unknown 56419649 Common - penicillin-binding protein (sporulation specific penicillin-binding protein) GK1114 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 56420450 Nonpathogen - hypothetical protein GK1915 6 None None None 56421966 Nonpathogen - hypothetical protein GK3431 6 None None None 56420397 Nonpathogen - hypothetical protein GK1862 1 None None None 56419840 Common - outer spore coat protein GK1305 3 None None None 56419286 Nonpathogen - hypothetical protein GK0751 1 None None None 56419672 Nonpathogen - hypothetical protein GK1137 1 None None None 56420715 Common birA biotin [acetyl-CoA carboxylase] synthetase ; transcriptional repressor of the biotin operon GK2180 228 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 56421281 Common - hypothetical protein GK2746 3 None None None 56420531 Common - hypothetical protein GK1996 87 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 56420438 Common - transposase GK1903 17 COG5421 COG5421, Transposase DNA replication, recombination, and repair 56420196 Common - branched-chain amino acid ABC transporter (permease) GK1661 159 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 56420521 Common - lipase GK1986 6 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 56420614 Common - thiol:disulfide interchange protein (thioredoxin) GK2079 204 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 56419257 Common - ABC transporter (ATP-binding protein) GK0722 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 56420237 Common - hypothetical protein GK1702 2 None None None 56419307 Common moeA molybdopterin cofactor biosynthesis protein GK0772 196 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 56421174 Common - hypothetical protein GK2639 3 None None None 56419434 Common - cytochrome c biogenesis protein GK0899 197 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 56419720 Common - L-serine dehydratase (L-serine deaminase) alpha chain GK1185 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 56419849 Common spoVK spore formation protein GK1314 147 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 56418585 Common - amino acid transporter GK0050 21 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 56420515 Common - two-component sensor histidine kinase GK1980 118 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 56421627 Common - carboxyl-terminal processing protease GK3092 184 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 56420224 Common - two-component sensor histidine kinase GK1689 221 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 56418542 Common - hypothetical protein GK0007 119 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 56421829 Common - hypothetical protein GK3294 76 COG1479 COG1479, Uncharacterized conserved protein Function unknown 56420205 Common - cytochrome c oxidase (b(o/a)3-type) chain II GK1670 40 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 56421926 Common - hypothetical protein GK3391 110 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 56421818 Common - hypothetical protein GK3283 40 COG3472 COG3472, Uncharacterized conserved protein Function unknown 56420353 Common - thimet oligopeptidase GK1818 89 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 56420927 Common - 1-deoxy-D-xylulose-5-phosphate synthase GK2392 228 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 56421095 Common - hypothetical protein GK2560 9 COG3881 COG3881, Uncharacterized protein conserved in bacteria Function unknown 56419706 Common def peptide deformylase GK1171 211 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 56421733 Common - NAD-dependent aldehyde dehydrogenase GK3198 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 56419383 Nonpathogen - hypothetical protein GK0848 1 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 56418956 Nonpathogen - hypothetical protein GK0421 1 None None None 56419167 Common - hypothetical protein GK0632 17 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 56420640 Common - hypothetical protein GK2105 10 COG4997 COG4997, Uncharacterized conserved protein Function unknown 56420847 Common - pyrimidine-nucleoside phosphorylase (PYNP) GK2312 118 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 56419561 Common - 3-oxoacyl-(acyl carrier protein) reductase GK1026 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 56419657 Common - hypothetical protein GK1122 5 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 56419498 Common - oligoendopeptidase F GK0963 61 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 56419283 Common - hypothetical protein GK0748 30 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 56421405 Common - hypothetical protein GK2870 4 None None None 56419346 Common - oligopeptide ABC transporter (oligopeptide-binding protein) GK0811 194 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 56421196 Common - acetolactate synthase catalytic subunit GK2661 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 56421392 Common - nitrate/sulfonate/taurine/bicarbonate ABC transporter (permease) GK2857 156 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 56418659 Common rpmD 50S ribosomal protein L30 GK0124 163 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 56419015 Common - hypothetical protein GK0480 3 None None None 56420875 Common - two-component response regulator GK2340 218 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 56421770 Nonpathogen - hypothetical protein GK3235 1 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 56419632 Common - hypothetical protein GK1097 3 None None None 56418538 Common - hypothetical protein GK0003 38 COG2501 COG2501, Uncharacterized conserved protein Function unknown 56418574 Common - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase GK0039 198 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 56419594 Common - dehydrogenase E1 component, beta subunit (lipoamide) GK1059 199 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 56420185 Nonpathogen - hypothetical protein GK1650 1 None None None 56420048 Nonpathogen - hypothetical protein GK1513 1 None None None 56420402 Common - assimilatory nitrite reductase subunit GK1867 92 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 56418561 Common - signal peptidase II GK0026 58 COG1774 COG1774, Uncharacterized homolog of PSP1 Function unknown 56420303 Common - hypothetical protein GK1768 11 COG4698 COG4698, Uncharacterized protein conserved in bacteria Function unknown 56419580 Common - hypothetical protein GK1045 143 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 56419786 Common pyrH uridylate kinase GK1251 235 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 56420406 Common - alcohol dehydrogenase GK1871 176 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 56421802 Nonpathogen - hypothetical protein GK3267 2 None None None 56420595 Nonpathogen - hypothetical protein GK2060 1 None None None 56420830 Common - bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein GK2295 232 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 56420896 Common - ABC transporter (ATP-binding protein) GK2361 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 56420670 Common - methylmalonyl-CoA decarboxylase GK2135 151 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 56421497 Common - homoserine kinase GK2962 120 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 56421753 Common - pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase) GK3218 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 56421851 Common - UDP-galactopyranose mutase GK3316 53 COG0562 Glf, UDP-galactopyranose mutase Cell envelope biogenesis, outer membrane 56420215 Nonpathogen - hypothetical protein GK1680 1 None None None 56422015 Common rpsR 30S ribosomal protein S18 (BS21) GK3480 215 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 56420899 Common - ABC transporter (ATP-binding protein) GK2364 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 56419588 Common - hypothetical protein GK1053 155 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 56420360 Common - acylglycerol lipase GK1825 65 COG1647 COG1647, Esterase/lipase General function prediction only 56420797 Common - histidinol-phosphate aminotransferase 1 (imidazole acetol-phosphate transaminase 1) (cobalamin biosynthesis) GK2262 228 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 56421245 Common - peptide methionine sulfoxide reductase GK2710 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 56419417 Nonpathogen - hypothetical protein GK0882 1 None None None 56421104 Common - hypothetical protein GK2569 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 56421495 Common - hypothetical protein GK2960 5 COG4837 COG4837, Uncharacterized protein conserved in bacteria Function unknown 56420630 Common - hypothetical protein GK2095 4 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 56421980 Common - transcription antiterminator GK3445 30 COG3711 BglG, Transcriptional antiterminator Transcription 56419864 Common - hypothetical protein GK1329 3 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 56420052 Common - subtilisin-type proteinase GK1517 149 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 56421463 Common - hypothetical protein GK2928 241 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 56421699 Common - acetyltransferase GK3164 208 COG1043 LpxA, Acyl- acyl carrier protein 56421977 Common - transposase (ISL3 family) GK3442 59 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 56419447 Common - ribonucleoside-diphosphate reductase beta subunit GK0912 157 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 56421562 Common - transcriptional regulator GK3027 118 COG1802 GntR, Transcriptional regulators Transcription 56420717 Common - hypothetical protein GK2182 231 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 56421974 Common - transposase GK3439 97 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 56418674 Common rplM 50S ribosomal protein L13 GK0139 221 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 56420593 Nonpathogen - hypothetical protein GK2058 1 None None None 56418969 Common - two-component response regulator GK0434 212 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 56419997 Common - hypothetical protein GK1462 5 COG4114 FhuF, Uncharacterized Fe-S protein General function prediction only 56421578 Common smpB SsrA-binding protein GK3043 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 56419213 Common comK competence transcription factor GK0678 5 COG4903 ComK, Genetic competence transcription factor Transcription 56419660 Common ftsZ cell division protein FtsZ GK1125 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 56420386 Common - hypothetical protein GK1851 21 COG2356 EndA, Endonuclease I DNA replication, recombination, and repair 56421209 Common - hypothetical protein GK2674 7 None None None 56421374 Common - hypothetical protein GK2839 3 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 56419813 Common - hypothetical protein GK1278 159 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 56420034 Common - transcriptional regulator (IclR family) GK1499 120 COG1414 IclR, Transcriptional regulator Transcription 56421331 Common - cysteine desulfurase GK2796 239 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 56419110 Common - hypothetical protein GK0575 49 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 56421299 Common - L-allo-threonine aldolase GK2764 102 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 56420465 Common ureC urease subunit alpha GK1930 97 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 56419027 Common - transcriptional repressor of PBSX genes GK0492 36 COG1396 HipB, Predicted transcriptional regulators Transcription 56418964 Common - RNA methyltransferase GK0429 197 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 56419272 Common - multidrug ABC transporter (ATP-binding protein) GK0737 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 56419621 Common - hypothetical protein GK1086 20 COG3336 COG3336, Predicted membrane protein Function unknown 56419362 Common - hypothetical protein GK0827 9 COG4116 COG4116, Uncharacterized protein conserved in bacteria Function unknown 56419150 Common - exo-alpha-1,4-glucosidase GK0615 173 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 56419615 Common ctaA heme O oxygenase GK1080 61 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 56419328 Common argD acetylornithine aminotransferase GK0793 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 56420790 Common - hypothetical protein GK2255 12 None None None 56421842 Common - transposase of IS642-like element GK3307 56 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 56421640 Nonpathogen - hypothetical conserved protein in Tn5401 GK3105 1 None None None 56421779 Nonpathogen - hypothetical protein GK3244 1 None None None 56420757 Common - hypothetical protein GK2222 5 None None None 56421955 Common - hypothetical protein GK3420 2 None None None 56418948 Common - uroporphyrin-III C-methyltransferase GK0413 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 56420162 Common - hypothetical protein GK1627 109 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 56420314 Common - aspartate aminotransferase GK1779 236 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 56420863 Nonpathogen - hypothetical protein GK2328 1 None None None 56421311 Common - ABC transporter GK2776 182 COG0661 AarF, Predicted unusual protein kinase General function prediction only 56421057 Common nadD nicotinic acid mononucleotide adenyltransferase GK2522 195 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 56418922 Common - D-isomer specific 2-hydroxyacid dehydrogenase GK0387 228 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 56421098 Common - tRNA (5-methylaminomethyl-2-thiouridylate)- methyltransferase GK2563 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 56421989 Common - amino acid ABC transporter (permease) GK3454 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 56418852 Common - hypothetical protein GK0317 13 None None None 56420678 Nonpathogen - hypothetical protein GK2143 1 None None None 56420429 Common - sugar ABC transporter (ATP-binding protein) GK1894 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 56419903 Common - imidazolone-5-propionate hydrolase GK1368 101 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 56421543 Common - 3-hydroxyacyl-CoA dehydrogenase GK3008 159 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 56418901 Common - anti-sigma factor antagonist GK0366 11 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 56419968 Common - hypothetical protein GK1433 14 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 56420616 Common - hypothetical protein GK2081 2 None None None 56419899 Common - hypothetical protein GK1364 33 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 56420068 Common - malate synthase G GK1533 93 COG2225 AceB, Malate synthase Energy production and conversion 56421284 Common - hypothetical protein GK2749 94 COG4109 COG4109, Predicted transcriptional regulator containing CBS domains Transcription 56421593 Common - glyceraldehyde-3-phosphate dehydrogenase GK3058 219 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 56421598 Common - phosphotransferase system phosphocarrier protein HPr GK3063 149 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 56418607 Common - hypothetical protein GK0072 24 COG1476 COG1476, Predicted transcriptional regulators Transcription 56421146 Common spoIVFB protease (stage IV sporulation protein FB) GK2611 71 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 56419731 Common - signal recognition particle GTPase GK1196 246 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 56420151 Common - spore germination protein GK1616 10 None None None 56420190 Common - short chain oxidoreductase GK1655 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 56421780 Common - K+-transporting ATPase d chain GK3245 92 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 56418971 Common - hypothetical protein GK0436 110 COG0397 COG0397, Uncharacterized conserved protein Function unknown 56421168 Nonpathogen - hypothetical protein GK2633 1 COG4795 PulJ, Type II secretory pathway, component PulJ Intracellular trafficking and secretion 56419927 Common - glutamyl-tRNA(Gln) amidotransferase subunit A GK1392 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 56421187 Common clpX ATP-dependent protease ATP-binding subunit GK2652 233 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 56419978 Common - multidrug resistance protein GK1443 138 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 56419247 Common - pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase) GK0712 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 56420529 Common - hypothetical protein GK1994 143 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 56421354 Common - NTPase GK2819 36 COG1986 COG1986, Uncharacterized conserved protein Function unknown 56419669 Common - hypothetical protein GK1134 33 COG2302 COG2302, Uncharacterized conserved protein, contains S4-like domain Function unknown 56418820 Common - transposase of IS652-like element GK0285 59 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 56421565 Common - hypothetical protein GK3030 181 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 56421551 Common - adenosylmethionine-8-amino-7-oxononanoate aminotransferase GK3016 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 56419176 Common - hypothetical protein GK0641 132 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 56420544 Common - ABC transporter (permease) GK2009 225 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 56421767 Nonpathogen - hypothetical protein GK3232 1 None None None 56419509 Common - spore germination protein GK0974 13 None None None 56421359 Common - hypothetical protein GK2824 3 None None None 56421334 Common - histidinol-phosphatase GK2799 33 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 56419696 Nonpathogen - hypothetical protein GK1161 1 None None None 56420373 Common - PTS system, fructose-specific enzyme II, BC component GK1838 143 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 56420986 Nonpathogen - hypothetical protein GK2451 6 None None None 56420811 Common - N-acetylglucosamine-6-phosphate isomerase GK2276 81 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 56418649 Common rpmC 50S ribosomal protein L29 GK0114 198 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 56419260 Common - spermidine/putrescine ABC transporter (permease) GK0725 202 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 56421532 Common - amino acid ABC transporter (substrate binding protein) (lipoprotein) GK2997 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 56420781 Common - inorganic pyrophosphatase (pyrophosphate phospho-hydrolase) GK2246 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 56420701 Nonpathogen - hypothetical protein GK2166 1 None None None 56420533 Nonpathogen - hypothetical protein GK1998 1 None None None 56421871 Common - chromate transporter GK3336 92 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 56421713 Common - hypothetical protein GK3178 23 COG2253 COG2253, Uncharacterized conserved protein Function unknown 56418798 Common - phosphoribosylformylglycinamidine synthase II GK0263 235 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 56421631 Common - mercuric reductase GK3096 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 56419799 Common - hypothetical protein GK1264 23 COG1550 COG1550, Uncharacterized protein conserved in bacteria Function unknown 56418873 Common - hypothetical protein GK0338 19 None None None 56422023 Common - hypothetical protein GK3488 48 COG1811 COG1811, Uncharacterized membrane protein, possible Na+ channel or pump General function prediction only 56420728 Common - hypothetical protein GK2193 3 None None None 56420176 Common - hypothetical protein GK1641 2 None None None 56421809 Common - sugar ABC transporter (sugar-binding protein) GK3274 75 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 56419470 Nonpathogen - hypothetical protein GK0935 4 None None None 56419098 Common - hypothetical protein GK0563 42 COG2738 COG2738, Predicted Zn-dependent protease General function prediction only 56421238 Common - hypothetical protein GK2703 181 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 56419495 Common - short chain dehydrogenase GK0960 4 None None None 56420141 Common - hypothetical protein GK1606 112 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 56420912 Common - branched-chain alpha-keto acid dehydrogenase E1 component beta chain (2-oxoisovalerate dehydrogenase beta subunit) GK2377 220 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 56421273 Common - hypothetical protein GK2738 51 COG0628 PerM, Predicted permease General function prediction only 56418549 Common - spore peptidoglycan hydrolase (N-acetylglucosaminidase) GK0014 90 COG3858 COG3858, Predicted glycosyl hydrolase General function prediction only 56419676 Nonpathogen - hypothetical protein GK1141 1 None None None 56421049 Common - hypothetical protein GK2514 2 None None None 56418592 Common spoIIE stage II sporulation protein E (serine phosphatase) GK0057 47 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 56418571 Common - hypothetical protein GK0036 11 None None None 56420921 Common - hypothetical protein GK2386 2 None None None 56421163 Common - twitching motility protein GK2628 177 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 56420981 Common - hypothetical protein GK2446 117 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 56421600 Common - hypothetical protein GK3065 97 COG0391 COG0391, Uncharacterized conserved protein Function unknown 56418781 Common - hypothetical protein GK0246 51 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 56421414 Common - hypothetical protein GK2879 75 COG2013 COG2013, Uncharacterized conserved protein Function unknown 56419855 Common - beta-ketothiolase (3-ketoacyl-CoA thiolase) GK1320 187 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 56420243 Common - transposase GK1708 25 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 56420911 Common - branched-chain alpha-keto acid dehydrogenase subunit E2 GK2376 196 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 56421231 Common - hypothetical protein GK2696 20 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 56419405 Common - glycosyltransferase GK0870 204 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 56421217 Common - nucleotide sugar epimerase GK2682 232 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 56419505 Common - hypothetical protein GK0970 23 COG3949 COG3949, Uncharacterized membrane protein Function unknown 56419069 Nonpathogen - hypothetical protein GK0534 3 COG5614 COG5614, Bacteriophage head-tail adaptor General function prediction only 56420280 Common treR transcriptional repressor of trehalose operon (GntR family) GK1745 105 COG2188 PhnF, Transcriptional regulators Transcription 56418688 Common - hypothetical protein GK0153 27 COG4856 COG4856, Uncharacterized protein conserved in bacteria Function unknown 56419826 Common - hypothetical protein GK1291 5 None None None 56419640 Common rpmF 50S ribosomal protein L32 GK1105 31 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 56421906 Common - ribose-5-phosphate isomerase B GK3371 128 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 56421040 Common - chaperone protein (heat shock protein) (HSP-70 cofactor) GK2505 231 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 56420645 Nonpathogen - hypothetical protein GK2110 4 None None None 56419914 Common - hypothetical protein GK1379 19 COG1700 COG1700, Uncharacterized conserved protein Function unknown 56419422 Common - hypothetical protein GK0887 18 COG5421 COG5421, Transposase DNA replication, recombination, and repair 56421470 Nonpathogen - hypothetical protein GK2935 1 None None None 56421558 Common - branched chain amino acid ABC transporter (ATP-binding protein) GK3023 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 56418917 Common - hypothetical protein GK0382 21 COG4877 COG4877, Uncharacterized protein conserved in bacteria Function unknown 56419831 Common - group II intron reverse transcriptase/maturase GK1296 84 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 56420974 Common - hypothetical protein GK2439 222 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 56421609 Common hisB imidazoleglycerol-phosphate dehydratase GK3074 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 56421896 Common - F0F1 ATP synthase subunit delta GK3361 185 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 56419711 Common - serine/threonine protein kinase GK1176 163 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 56420736 Common trpF N-(5'-phosphoribosyl)anthranilate isomerase GK2201 192 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 56421827 Common - hypothetical protein GK3292 3 None None None 56421948 Common - hypothetical protein GK3413 3 None None None 56420021 Nonpathogen - hypothetical protein GK1486 1 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 56420039 Nonpathogen - hypothetical protein GK1504 2 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 56419074 Common - bacteriophage-related protein GK0539 100 COG5280 COG5280, Phage-related minor tail protein Function unknown 56419839 Common - hypothetical protein GK1304 8 COG4550 COG4550, Predicted membrane protein Function unknown 56420073 Common - hypothetical protein GK1538 20 COG3359 COG3359, Predicted exonuclease DNA replication, recombination, and repair 56420078 Common - hypothetical protein GK1543 135 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 56420287 Common - hypothetical protein GK1752 133 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 56420559 Common - pyruvate dehydrogenase E1 (lipoamide) beta subunit GK2024 181 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 56421792 Common - hypothetical protein GK3257 45 None None None 56421931 Nonpathogen - hypothetical protein GK3396 1 None None None 56421006 Common - metal (zinc) ABC transporter (ATP-binding protein) GK2471 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 56419268 Nonpathogen - hypothetical protein GK0733 1 None None None 56421521 Common - transporter GK2986 123 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 56421479 Common - biotin biosynthesis protein GK2944 112 COG1268 BioY, Uncharacterized conserved protein General function prediction only 56421080 Common - hypothetical protein GK2545 4 None None None 56419119 Common - cadmium efflux system accessory protein (cadmium-binding protein) GK0584 126 COG0640 ArsR, Predicted transcriptional regulators Transcription 56419002 Nonpathogen - hypothetical protein GK0467 1 None None None 56418621 Common - hypothetical protein GK0086 39 COG1939 COG1939, Uncharacterized protein conserved in bacteria Function unknown 56419418 Common - hypothetical protein GK0883 9 None None None 56420479 Common - transposase GK1944 34 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 56420014 Common - anti-sigmaB factor antagonist GK1479 7 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 56419600 Common cad lysine decarboxylase (LDC) GK1065 114 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 56420216 Nonpathogen - hypothetical protein GK1681 1 None None None 56420969 Common comGB DNA transport machinery GK2434 99 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 56421268 Common - hypothetical protein GK2733 63 COG2030 MaoC, Acyl dehydratase Lipid metabolism 56419523 Nonpathogen - hypothetical protein GK0988 1 None None None 56420726 Common qcrB cytochrome b6 GK2191 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 56421615 Common - hypothetical protein GK3080 22 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 56421754 Common - hypothetical protein GK3219 57 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 56419083 Common - hypothetical protein GK0548 13 COG4824 COG4824, Phage-related holin (Lysis protein) General function prediction only 56420582 Nonpathogen - hypothetical protein GK2047 1 None None None 56420128 Nonpathogen - hypothetical protein GK1593 1 None None None 56421661 Common - UDP-N-acetylglucosamine-2-epimerase (5.1.3.-) GK3126 46 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 56420256 Common - transposase GK1721 30 None None None 56419460 Common - hypothetical protein GK0925 14 COG3375 COG3375, Uncharacterized conserved protein Function unknown 56422005 Common - hypothetical protein GK3470 65 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 56418885 Common - hypothetical protein GK0350 62 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 56420575 Common - hypothetical protein GK2040 14 None None None 56418842 Common - lantibiotic biosynthesis protein (sensory transduction protein kinase) GK0307 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 56420291 Common - hypothetical protein GK1756 124 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 56418853 Common - hypothetical protein GK0318 8 None None None 56419326 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein GK0791 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 56420932 Common nusB transcription antitermination protein NusB GK2397 195 COG0781 NusB, Transcription termination factor Transcription 56420431 Common - sugar ABC transporter (sugar-binding protein) GK1896 119 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 56420828 Common - hypothetical protein GK2293 5 COG3153 COG3153, Predicted acetyltransferase General function prediction only 56419188 Common - hypothetical protein GK0653 2 None None None 56420414 Common - D-xylose ABC transporter (permease) GK1879 142 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 56420005 Common - 6-pyruvoyltetrahydropterin synthase(PTP synthase) GK1470 75 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 56421125 Common - hypothetical protein GK2590 11 None None None 56419000 Common - enoyl-(acyl carrier protein) reductase GK0465 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 56420738 Common trpD anthranilate phosphoribosyltransferase GK2203 218 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 56419298 Common - molybdopterin-guanine dinucleotide biosynthesis protein GK0763 117 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 56420485 Nonpathogen - hypothetical protein GK1950 3 COG2886 COG2886, Uncharacterized small protein Function unknown 56420490 Common - galactonate dehydratase GK1955 112 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 56421882 Common - NADH dehydrogenase subunit L GK3347 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 56419125 Common - transcriptional regulator (marR family) GK0590 42 COG1846 MarR, Transcriptional regulators Transcription 56418801 Common purN phosphoribosylglycinamide formyltransferase GK0266 222 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 56419559 Common - dihydrolipoamide acetyltransferase GK1024 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 56420452 Common - hypothetical protein GK1917 64 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 56420564 Common - ABC transporter (permease) GK2029 96 COG4120 COG4120, ABC-type uncharacterized transport system, permease component General function prediction only 56421706 Common - hypothetical protein GK3171 4 None None None 56421085 Common - protease GK2550 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 56418763 Common acpS 4'-phosphopantetheinyl transferase GK0228 146 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 56419947 Common - hypothetical protein GK1412 33 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 56418990 Common sspK acid-soluble spore protein K GK0455 2 None None None 56418623 Common - hypothetical protein GK0088 29 COG3688 COG3688, Predicted RNA-binding protein containing a PIN domain General function prediction only 56418615 Common - hypothetical protein GK0080 47 COG4956 COG4956, Integral membrane protein (PIN domain superfamily) General function prediction only 56419516 Common - spore cortex-lytic enzyme GK0981 40 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 56421151 Common mreC cell-shape determining protein GK2616 154 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 56421994 Common qoxA cytochrome aa3 quinol oxidase subunit II GK3459 146 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 56418635 Common - ribosomal protein (L7AE family) GK0100 28 COG1358 RPL8A, Ribosomal protein HS6-type (S12/L30/L7a) Translation, ribosomal structure and biogenesis 56420458 Common - multidrug-efflux transporter GK1923 200 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 56419976 Common - hypothetical protein GK1441 18 COG4821 COG4821, Uncharacterized protein containing SIS (Sugar ISomerase) phosphosugar binding domain General function prediction only 56421586 Nonpathogen - hypothetical protein GK3051 1 None None None 56418811 Common ligA NAD-dependent DNA ligase LigA GK0276 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 56420682 Common - transcriptional regulator GK2147 124 COG1609 PurR, Transcriptional regulators Transcription 56421581 Common secG preprotein translocase subunit SecG GK3046 19 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 56421387 Common - hypothetical protein GK2852 33 COG5464 COG5464, Uncharacterized conserved protein Function unknown 56419391 Common - hypothetical protein GK0856 8 None None None 56420666 Common - hypothetical protein GK2131 17 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 56420865 Common - hypothetical protein GK2330 100 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 56421077 Common - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase GK2542 103 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 56421604 Common - hypothetical protein GK3069 7 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 56421324 Common - hypothetical protein GK2789 9 None None None 56420063 Common - hydroxypyruvate isomerase GK1528 81 COG3622 Hfi, Hydroxypyruvate isomerase Carbohydrate transport and metabolism 56418714 Common - uridine kinase GK0179 51 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 56419152 Common - antibiotic resistance protein (antibiotic efflux protein) GK0617 82 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 56418987 Common - hypothetical protein GK0452 62 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 56418890 Common - hypothetical protein GK0355 86 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 56419603 Common - myo-inositol-1(or 4)-monophosphatase (inositol-1-phosphatase) (I-1-Pase) GK1068 208 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 56419227 Common - spore germination protein GK0692 2 None None None 56418991 Common - hypothetical protein GK0456 28 COG1988 COG1988, Predicted membrane-bound metal-dependent hydrolases General function prediction only 56420889 Common - hypothetical protein GK2354 6 None None None 56418776 Common moaC molybdenum cofactor biosynthesis protein C GK0241 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 56419220 Common - spore germination protein GK0685 2 None None None 56419206 Common - ABC transporter (ATP-binding protein) GK0671 249 COG1101 PhnK, ABC-type uncharacterized transport system, ATPase component General function prediction only 56419178 Common - hypothetical protein GK0643 3 None None None 56419795 Common nusA transcription elongation factor NusA GK1260 220 COG0195 NusA, Transcription elongation factor Transcription 56419128 Common - phosphinothricin N-acetyltransferase GK0593 100 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 56419925 Common - hypothetical protein GK1390 29 COG4127 COG4127, Uncharacterized conserved protein Function unknown 56420832 Common - riboflavin-specific deaminase (diaminohydroxyphosphoribosylaminopyrimidine deaminase ; 5-amino-6-(5-phosphoribosylamino)uracil reductase ) GK2297 231 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 56419311 Common - hypothetical protein GK0776 10 None None None 56420765 Common - sporulation protein GK2230 14 None None None 56418739 Nonpathogen - hypothetical protein GK0204 1 None None None 56421868 Common - cell shape determining protein (MreB-like protein) GK3333 236 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 56419814 Common - hypothetical protein GK1279 13 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 56421968 Common - metabolite transporter GK3433 140 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 56421721 Common - surface layer (S-layer) glycoprotein GK3186 9 None None None 56418897 Common - hypothetical protein GK0362 19 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 56419139 Common - cytochrome bd-type ubiquinol oxidase subunit I GK0604 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 56420672 Common - hypothetical protein GK2137 17 COG2259 COG2259, Predicted membrane protein Function unknown 161551793 Common - hypothetical protein GK2594 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 56420931 Common - methylenetetrahydrofolate dehydrogenase ; methenyltetrahydrofolate cyclohydrolase GK2396 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 56419768 Common fliZ flagellar biosynthetic protein GK1233 3 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 56420611 Common - hypothetical protein GK2076 40 COG2210 COG2210, Uncharacterized conserved protein Function unknown 56422025 Common - sporulation initiation inhibitor protein GK3490 231 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 56419341 Common - hypothetical protein GK0806 3 COG5504 COG5504, Predicted Zn-dependent protease Posttranslational modification, protein turnover, chaperones 56419870 Common - ABC transporter (ATP-binding protein) GK1335 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 56420906 Common - methylmalonyl-CoA mutase small subunit GK2371 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 56419024 Common - phage-like element PBSX protein GK0489 3 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 56420963 Nonpathogen - hypothetical protein GK2428 1 None None None 56420100 Common - hypothetical protein GK1565 7 COG4841 COG4841, Uncharacterized protein conserved in bacteria Function unknown 56420742 Common aroF chorismate synthase GK2207 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 56418788 Common - hypothetical protein GK0253 104 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 56419893 Common - sporulation control protein GK1358 18 COG4326 Spo0M, Sporulation control protein General function prediction only 56420948 Common - hypothetical protein GK2413 31 COG3872 COG3872, Predicted metal-dependent enzyme General function prediction only 56421961 Common - hypothetical protein GK3426 26 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 56421672 Common flgK flagellar hook-associated protein FlgK GK3137 124 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 56421037 Common prmA ribosomal protein L11 methyltransferase GK2502 188 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 56419348 Common - oligopeptide ABC transporter (permease) GK0813 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 56420260 Common - hypothetical protein GK1725 18 None None None 56421154 Common maf Maf-like protein GK2619 197 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 56419309 Common moaE molybdopterin converting factor (subunit 2) GK0774 161 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 56420507 Common - transporter GK1972 131 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 56420959 Common - glycine dehydrogenase subunit 1 GK2424 172 COG0403 GcvP, Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain Amino acid transport and metabolism 56420392 Common - PTS system, cellobiose-specific enzyme II, C component GK1857 39 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 56420629 Common - hypothetical protein GK2094 28 None None None 56418564 Common - hypothetical protein GK0029 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 56419901 Common - hypothetical protein GK1366 118 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 56419288 Common - hypothetical protein GK0753 157 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 56421022 Common - hypothetical protein GK2487 2 None None None 56421253 Common infC translation initiation factor IF-3 GK2718 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 56418867 Common - serine protease Do GK0332 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 56418725 Common - alkaline phosphatase GK0190 115 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 56419096 Common - C4-dicarboxylate transporter DctA GK0561 159 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 56420221 Common - serine/threonine protein kinase GK1686 131 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 56419182 Nonpathogen - hypothetical protein GK0647 1 None None None 56418746 Common - sulfatase GK0211 67 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 56421220 Common - thioredoxin (TRX) GK2685 235 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 56421715 Common - amylopullulanase GK3180 156 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 56419029 Common - transcriptional repressor of PBSX genes GK0494 33 COG1476 COG1476, Predicted transcriptional regulators Transcription 56419886 Common - hypothetical protein GK1351 8 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 56421360 Common - hypothetical protein GK2825 11 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 56421658 Common - N-acetyl neuramic acid synthetase (capsular polysaccharide biosynthesis) GK3123 78 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 56420222 Nonpathogen - hypothetical protein GK1687 1 None None None 56420498 Common - hypothetical protein GK1963 64 COG1641 COG1641, Uncharacterized conserved protein Function unknown 56421761 Common - ribose ABC transporter (ribose-binding protein) GK3226 122 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 56418716 Common - transcriptional regulator GK0181 51 COG3655 COG3655, Predicted transcriptional regulator Transcription 56420381 Common - hypothetical protein GK1846 26 COG3654 Doc, Prophage maintenance system killer protein General function prediction only 56421982 Common - hypothetical protein GK3447 35 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 56419671 Common ileS isoleucyl-tRNA synthetase GK1136 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 56418818 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B GK0283 213 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 56419436 Common - hypothetical protein GK0901 105 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 56419132 Common - transcriptional regulator GK0597 2 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 56419966 Common - glutamate synthaselarge subunit GK1431 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 56420239 Common - hypothetical protein GK1704 83 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 56418696 Nonpathogen - hypothetical protein GK0161 9 None None None 56419647 Common ftsL cell division protein GK1112 5 COG4839 FtsL, Protein required for the initiation of cell division Cell division and chromosome partitioning 56420422 Common iolA methylmalonate-semialdehyde dehydrogenase GK1887 223 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 56419723 Common - fatty acid/phospholipid synthesis protein GK1188 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 56419331 Common - ornithine carbamoyltransferase GK0796 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 56421833 Common - hypothetical protein GK3298 4 COG2327 WcaK, Uncharacterized conserved protein Function unknown 56421629 Common - hypothetical protein GK3094 139 COG1741 COG1741, Pirin-related protein General function prediction only 56418668 Common rpoA DNA-directed RNA polymerase subunit alpha GK0133 218 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 56419842 Common mutL DNA mismatch repair protein GK1307 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 56420296 Common - threonine synthase GK1761 210 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 56421768 Common - hypothetical protein GK3233 12 COG5652 COG5652, Predicted integral membrane protein Function unknown 56419252 Common - bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein GK0717 179 COG0646 MetH, Methionine synthase I (cobalamin-dependent), methyltransferase domain Amino acid transport and metabolism 56421912 Common - protoporphyrinogen oxidase GK3377 227 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 56421215 Common - hypothetical protein GK2680 42 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 56418707 Common - Hnh endonuclease GK0172 22 COG3183 COG3183, Predicted restriction endonuclease Defense mechanisms 56418628 Common rplK 50S ribosomal protein L11 GK0093 249 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 56418748 Common - hypothetical protein GK0213 47 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 56421488 Common - NADH dehydrogenase GK2953 207 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 56420612 Common - hypothetical protein GK2077 61 COG3858 COG3858, Predicted glycosyl hydrolase General function prediction only 56419457 Common - hypothetical protein GK0922 47 COG2966 COG2966, Uncharacterized conserved protein Function unknown 56421508 Common - hypothetical protein GK2973 3 None None None 56422013 Common - hypothetical protein GK3478 90 COG3887 COG3887, Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain Signal transduction mechanisms 56419744 Common sucD succinyl-CoA synthetase subunit alpha GK1209 214 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 56418732 Common - acyl-CoA dehydrogenase GK0197 167 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 56420953 Common - spore peptidoglycan hydrolase (N-acetylglucosaminidase) GK2418 114 COG3858 COG3858, Predicted glycosyl hydrolase General function prediction only 56419005 Common - hypothetical protein GK0470 15 COG4129 COG4129, Predicted membrane protein Function unknown 56420328 Common - nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase GK1793 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 56419374 Common - NDP-sugar epimerase GK0839 232 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 56420843 Common sigF sporulation sigma factor SigF GK2308 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 56418578 Common - UDP-N-acetylglucosamine pyrophosphorylase GK0043 236 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 56420268 Common - hypothetical protein GK1733 33 COG4548 NorD, Nitric oxide reductase activation protein Inorganic ion transport and metabolism 56419771 Common fliR flagellar biosynthesis protein FliR GK1236 24 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 56421134 Common - quinolinate synthetase GK2599 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 56420990 Common - peptidoglycan biosynthesis (penicillin-binding protein 2A) GK2455 192 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 56419197 Common hemH ferrochelatase GK0662 170 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 56418834 Nonpathogen - hypothetical protein GK0299 1 None None None 56419333 Common - hypothetical protein GK0798 3 None None None 56421456 Common - hypothetical protein GK2921 3 None None None 56421505 Common - hypothetical protein GK2970 3 None None None 56420852 Common - transcriptional regulator (Fur family) (ferric uptake regulator) GK2317 206 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 56418808 Common - hypothetical protein GK0273 21 COG4496 COG4496, Uncharacterized protein conserved in bacteria Function unknown 56420523 Common - sodium dependent transporter GK1988 87 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 56421938 Nonpathogen - hypothetical protein GK3403 12 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 56418559 Common - thymidylate kinase GK0024 227 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 56421367 Common - transcriptional regulator (DeoR family) GK2832 2 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 56420562 Common - pyruvate dehydrogenase E1 (lipoamide) alpha subunit GK2027 154 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 56421889 Common - NADH dehydrogenase subunit C GK3354 177 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 56421776 Common - hypothetical protein GK3241 10 None None None 56418595 Common - hypothetical protein GK0060 230 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 56420334 Common - precorrin-2 methylase GK1799 123 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 56420877 Common - ABC transporter (ATP-binding protein) GK2342 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 56421172 Common - folyl-polyglutamate synthetase GK2637 217 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 56418643 Common rplW 50S ribosomal protein L23 GK0108 200 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 56421666 Common hag flagellin protein GK3131 116 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 56420114 Nonpathogen - hypothetical protein GK1579 1 None None None 56419449 Nonpathogen - hypothetical protein GK0914 6 COG0633 Fdx, Ferredoxin Energy production and conversion 56419035 Nonpathogen - hypothetical protein GK0500 1 None None None 56418883 Nonpathogen - hypothetical protein GK0348 6 None None None 56418657 Common rplR 50S ribosomal protein L18 GK0122 217 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 56419537 Common - transposase GK1002 18 COG5421 COG5421, Transposase DNA replication, recombination, and repair 56419146 Nonpathogen - hypothetical protein GK0611 5 None None None 56421439 Common - transposase GK2904 96 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 56419708 Common - RNA-binding Sun protein GK1173 209 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 56418912 Common - carbon monoxide dehydrogenase small subunit GK0377 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 56421697 Common - UDP-N-acetylglucosamine 2-epimerase GK3162 152 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 56421919 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase GK3384 222 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 56421092 Common - hypothetical protein GK2557 188 COG0628 PerM, Predicted permease General function prediction only 56419571 Nonpathogen - hypothetical protein GK1036 2 COG5582 COG5582, Uncharacterized conserved protein Function unknown 56418784 Common groEL chaperonin GroEL GK0249 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 56420065 Common - glycolate oxidase subunit GK1530 195 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 56419985 Common - hypothetical protein GK1450 2 None None None 56421472 Common - hypothetical protein GK2937 2 None None None 56419062 Nonpathogen - hypothetical protein GK0527 1 None None None 56420471 Common - ABC transporter (permease) GK1936 169 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 56418642 Common rplD 50S ribosomal protein L4 GK0107 219 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 56420375 Common - transcriptional regulator (DeoR family) GK1840 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 56421794 Common - hypothetical protein GK3259 20 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 56419023 Common - site-specific recombinase GK0488 84 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 56420127 Nonpathogen - hypothetical protein GK1592 1 None None None 56419837 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit beta GK1302 109 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 56419442 Common - two-component sensor histidine kinase GK0907 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 56418650 Common rpsQ 30S ribosomal protein S17 GK0115 231 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 56421979 Common - PTS system, sucrose-specific enzyme II, BC component GK3444 42 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 56419006 Common - glutamate-1-semialdehyde aminotransferase GK0471 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 56421908 Common - protein-tyrosine phosphatase GK3373 94 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 56421236 Common - alkaline phosphatase GK2701 86 COG1785 PhoA, Alkaline phosphatase Inorganic ion transport and metabolism 56421019 Common - hypothetical protein GK2484 112 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 56419114 Common - transposase GK0579 92 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 56421622 Common - hypothetical protein GK3087 3 COG4897 CsbA, Uncharacterized protein conserved in bacteria Function unknown 56421539 Common - glycine cleavage system protein H GK3004 188 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 56420591 Common aroK shikimate kinase GK2056 197 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 56419076 Common - hypothetical protein GK0541 5 None None None 56421482 Common pepA leucyl aminopeptidase GK2947 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 56421432 Common - hydantoin racemase GK2897 43 COG4126 COG4126, Hydantoin racemase Amino acid transport and metabolism 56421305 Nonpathogen - hypothetical protein GK2770 2 None None None 56421946 Common - hypothetical protein GK3411 87 COG1078 COG1078, HD superfamily phosphohydrolases General function prediction only 56421415 Common - transposase GK2880 67 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 56420601 Common - hypothetical protein GK2066 191 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 56419811 Common dapG aspartate kinase I GK1276 233 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 56422029 Common trmE tRNA modification GTPase TrmE GK3494 232 COG0486 ThdF, Predicted GTPase General function prediction only 56419262 Common - 1,3 propanediol dehydrogenase GK0727 171 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 56419270 Nonpathogen - hypothetical protein GK0735 1 None None None 56419858 Common - hypothetical protein GK1323 132 COG2860 COG2860, Predicted membrane protein Function unknown 56420290 Common - hypothetical protein GK1755 10 COG3937 COG3937, Uncharacterized conserved protein Function unknown 56418981 Common - hypothetical protein GK0446 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 56418582 Common - hypothetical protein GK0047 3 None None None 56421645 Common - hypothetical protein GK3110 122 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 56420285 Common - DNA topoisomerase IV subunit A GK1750 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 56420636 Common - transposase GK2101 74 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 56421560 Common - branched amino acid ABC transporter (permease) GK3025 158 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 56419481 Common - ribose ABC transporter (permease) GK0946 153 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 56419863 Common - LexA repressor GK1328 172 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 56421412 Common - 1,4-dihydroxy-2-naphthoate octaprenyltransferase GK2877 118 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 56420448 Common - sugar ABC transporter (sugar-binding protein) GK1913 105 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 56421166 Common - hypothetical protein GK2631 14 COG3881 COG3881, Uncharacterized protein conserved in bacteria Function unknown 56421894 Common - F0F1 ATP synthase subunit gamma GK3359 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 56419279 Common - hypothetical protein GK0744 115 COG3177 COG3177, Uncharacterized conserved protein Function unknown 56419402 Common - cystathionine beta-lyase GK0867 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 56418809 Common - geranylgeranylglyceryl phosphate synthase-like protein GK0274 31 COG1646 COG1646, Predicted phosphate-binding enzymes, TIM-barrel fold General function prediction only 56419916 Common - type I restriction-modification system specificity protein GK1381 86 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 56421055 Common - hypothetical protein GK2520 198 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 56420257 Common - hypothetical protein GK1722 66 COG0583 LysR, Transcriptional regulator Transcription 56418583 Common - transcription-repair coupling factor GK0048 238 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 56419704 Common - pantothenate metabolism flavoprotein GK1169 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 56420546 Common - ABC transporter (substrate-binding protein) GK2011 143 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 56419249 Nonpathogen - hypothetical protein GK0714 1 None None None 56421308 Common - hypothetical protein GK2773 6 None None None 56421185 Common - ATP-dependent Lon protease GK2650 219 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 56418705 Common - transcriptional regulator (AraC/XylS family) GK0170 139 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 56419177 Common - coproporphyrinogen III oxidase GK0642 200 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 56421477 Common - hypothetical protein GK2942 18 None None None 56419907 Common - hypothetical protein GK1372 29 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 56421970 Common - hypothetical protein GK3435 2 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 56420704 Common nth endonuclease III (DNA-(apurinic or apyrimidinic site) lyase) GK2169 240 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 56418756 Common - alkaline phosphatase GK0221 146 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 56419717 Common - hypothetical protein GK1182 38 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 56420299 Nonpathogen - hypothetical protein GK1764 1 None None None 56420783 Common - histidinol phosphatase GK2248 35 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 56419507 Common - spore germination protein GK0972 15 None None None 56420083 Nonpathogen - hypothetical protein GK1548 1 None None None 56420192 Common - hypothetical protein GK1657 66 COG2030 MaoC, Acyl dehydratase Lipid metabolism 56420782 Common - phosphoglycerate dehydrogenase GK2247 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 56421616 Common - prolipoprotein diacylglyceryl transferase GK3081 175 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 56418865 Common - hypothetical protein GK0330 221 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 56420382 Nonpathogen - hypothetical protein GK1847 1 None None None 56419809 Common spoVFB dipicolinate synthase subunit B GK1274 14 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 56421595 Common - hypothetical protein GK3060 15 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 56419515 Common - hypothetical protein GK0980 4 COG4873 COG4873, Uncharacterized protein conserved in bacteria Function unknown 56420922 Common spo0A stage 0 sporulation protein A (two-component response regulator) GK2387 223 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 56418826 Common - ABC transporter (ATP-binding protein) GK0291 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 56419243 Common - transcriptional regulator involved in carbon catabolite control GK0708 129 COG1609 PurR, Transcriptional regulators Transcription 56421144 Common - hypothetical protein GK2609 19 COG2868 COG2868, Predicted ribosomal protein Translation, ribosomal structure and biogenesis 56420441 Common araD L-ribulose-5-phosphate 4-epimerase GK1906 119 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 56420399 Common - transcriptional regulator (MarR family) GK1864 143 COG1846 MarR, Transcriptional regulators Transcription 56420929 Common - exodeoxyribonuclease VII small subunit (exonuclease VII small subunit) GK2394 12 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 56421878 Common - unknwon conserved protein GK3343 7 COG4836 COG4836, Predicted membrane protein Function unknown 56419497 Common - amino acid ABC transporter (permease) GK0962 113 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 56421786 Common - N-acyl-L-amino acid amidohydrolase (L-aminoacylase) GK3251 168 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 56419472 Common - multidrug resistance protein GK0937 215 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 56421921 Common - fructose-bisphosphate aldolase GK3386 179 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 56420273 Common - hypothetical protein GK1738 151 COG1959 COG1959, Predicted transcriptional regulator Transcription 56418726 Common - ferrichrome ABC transporter (permease) GK0191 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 56418653 Common rplE 50S ribosomal protein L5 GK0118 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 56421571 Common - manganese catalase GK3036 42 COG3546 COG3546, Mn-containing catalase Inorganic ion transport and metabolism 56421901 Common - hypothetical protein GK3366 2 COG5336 COG5336, Uncharacterized protein conserved in bacteria Function unknown 56419524 Common - hydrolase GK0989 175 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 56421990 Common - amino acid ABC transporter (ATP-binding protein) GK3455 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 56419503 Common - ATP-dependent Clp protease GK0968 217 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 56420178 Common - ABC transporter (ATP-binding protein) GK1643 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 56421530 Common - ABC transporter (ATP-binding protein) GK2995 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 56419231 Common - hypothetical protein GK0696 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 56421899 Common - F0F1 ATP synthase subunit A GK3364 196 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 56421198 Common - transposase GK2663 45 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 56420366 Common - metal-dependent protease GK1831 24 COG4412 COG4412, Uncharacterized protein conserved in bacteria Function unknown 56419215 Common - signal peptidase I (SPase I) GK0680 199 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 56421811 Common - hypothetical protein GK3276 17 COG5464 COG5464, Uncharacterized conserved protein Function unknown 56420055 Common - hypothetical protein GK1520 7 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 56420139 Nonpathogen - hypothetical protein GK1604 1 None None None 56418977 Common - NADH dehydrogenase subunit 5 GK0442 205 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 56420661 Common - hypothetical protein GK2126 35 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 56421985 Common - pyridoxal kinase GK3450 219 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 56421072 Nonpathogen - hypothetical protein GK2537 1 None None None 56421247 Common - small acid-soluble spore protein SspI GK2712 4 None None None 56421516 Common - hypothetical protein GK2981 13 None None None 56421637 Common - cytochrome c551 GK3102 8 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 56420675 Common - leucyl aminopeptidase II GK2140 56 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 56421857 Nonpathogen - hypothetical protein GK3322 1 COG4938 COG4938, Uncharacterized conserved protein Function unknown 56419991 Common - hypothetical protein GK1456 2 None None None 56421960 Common - hypothetical protein GK3425 111 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 56421010 Common - ATP-dependent RNA helicase GK2475 237 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 56421047 Common rpsT 30S ribosomal protein S20 GK2512 215 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 56418685 Common - RNA polymerase sigma factor SigW GK0150 176 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 56418993 Common - hypothetical protein GK0458 8 COG2427 COG2427, Uncharacterized conserved protein Function unknown 56420312 Common - hypothetical protein GK1777 3 None None None 56419154 Common - hypothetical protein GK0619 24 COG4721 COG4721, Predicted membrane protein Function unknown 56418920 Common hutH histidine ammonia-lyase GK0385 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 56419240 Common - maltose/maltodextrin transport system (permease) GK0705 155 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 56418730 Nonpathogen - hypothetical protein GK0195 1 None None None 56420301 Common - hypothetical protein GK1766 170 COG0344 COG0344, Predicted membrane protein Function unknown 56418915 Common - hypothetical protein GK0380 58 COG2068 COG2068, Uncharacterized MobA-related protein General function prediction only 56420818 Common - ribosomal large subunit pseudouridine synthaseB (pseudouridylate synthase) (uracil hydrolyase) GK2283 205 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 56419358 Nonpathogen - hypothetical protein GK0823 1 None None None 56418864 Nonpathogen - hypothetical protein GK0329 1 None None None 56419238 Common - alpha-cyclodextrinase GK0703 177 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 56421001 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase GK2466 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 56419208 Common - branched-chain amino acid transporter GK0673 107 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 56418737 Common - protein-disulfide isomerase GK0202 90 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 56420157 Nonpathogen - hypothetical protein GK1622 3 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 56418902 Common - hypothetical protein GK0367 139 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 56420734 Common trpA tryptophan synthase subunit alpha GK2199 215 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 56418961 Common - fumarate hydratase class I (fumarase) GK0426 148 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 56421777 Common - N-acyl-L-amino acid amidohydrolase (L-aminoacylase) GK3242 167 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 56420095 Common sspN acid-soluble spore protein N GK1560 2 None None None 56418849 Common - glycine betaine/carnitine/choline ABC transporter (ATP-binding protein) GK0314 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 56419846 Common - methyl-accepting chemotaxis protein GK1311 127 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 56419935 Common - S-adenosylmethionine decarboxylase GK1400 31 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 56421953 Common - hypothetical protein GK3418 5 None None None 56418891 Common - hypothetical protein GK0356 59 COG1959 COG1959, Predicted transcriptional regulator Transcription 56418754 Common murG N-acetylglucosaminyl transferase GK0219 208 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 56420389 Common - hypothetical protein GK1854 4 None None None 56421630 Common - transcriptional regulator involved in mercury resistance operon GK3095 157 COG0789 SoxR, Predicted transcriptional regulators Transcription 56421464 Common - transcriptional regulator (Lrp/AsnC family) GK2929 83 COG1522 Lrp, Transcriptional regulators Transcription 56421298 Common - hypothetical protein GK2763 60 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 56418907 Common - aspartate aminotransferase GK0372 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 56420092 Nonpathogen - hypothetical protein GK1557 1 None None None 56421576 Nonpathogen - hypothetical protein GK3041 1 None None None 56418932 Nonpathogen - hypothetical protein GK0397 1 None None None 56420795 Common - cobalamin-5-phosphate synthase GK2260 37 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 56421937 Common - hypothetical protein GK3402 13 COG4506 COG4506, Uncharacterized protein conserved in bacteria Function unknown 56420153 Common - spore germination protein GK1618 14 None None None 56421494 Common - NADH dehydrogenase GK2959 193 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 56420345 Common - cobalamin biosynthesis protein GK1810 68 COG3411 COG3411, Ferredoxin Energy production and conversion 56420499 Common - hypothetical protein GK1964 65 COG1691 COG1691, NCAIR mutase (PurE)-related proteins General function prediction only 56420839 Common - stage V sporulation protein AD GK2304 15 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 56420203 Common - chromate transporter GK1668 110 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 56418939 Common - siroheme synthase GK0404 135 COG1648 CysG, Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) Coenzyme metabolism 56419474 Nonpathogen - hypothetical protein GK0939 1 None None None 56419159 Common - sulfur carrier protein ThiS GK0624 29 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 56419578 Common - hypothetical protein GK1043 107 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 56419013 Common - transcriptional regulator (Fur family) GK0478 209 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 56420210 Common - phage infection protein GK1675 30 COG1511 COG1511, Predicted membrane protein Function unknown 56419592 Common def peptide deformylase GK1057 213 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 56419448 Common - hypothetical protein GK0913 3 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 56419921 Common - hypothetical protein GK1386 11 COG4443 COG4443, Uncharacterized protein conserved in bacteria Function unknown 56421314 Common - enoyl-CoA hydratase/carnithine racemase GK2779 183 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 56418945 Nonpathogen - hypothetical protein GK0410 1 None None None 56420573 Common - enoyl-CoA hydratase subunit II (phenylacetic acid catabolism) GK2038 176 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 56418877 Common - RNA methyltransferase GK0342 204 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 56420849 Common - phosphopentomutase GK2314 70 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 56420028 Common - hypothetical protein GK1493 98 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 56420897 Nonpathogen - hypothetical protein GK2362 1 COG1480 COG1480, Predicted membrane-associated HD superfamily hydrolase General function prediction only 56419355 Common cls cardiolipin synthetase GK0820 150 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 56421203 Common - glutamate racemase GK2668 189 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 56420049 Common - hypothetical protein GK1514 2 None None None 56420890 Nonpathogen - hypothetical protein GK2355 3 None None None 56420408 Nonpathogen - hypothetical protein GK1873 1 None None None 56419654 Common spoVE stage V sporulation protein E GK1119 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 56421420 Common - transcriptional regulator (TetR family) GK2885 91 COG1309 AcrR, Transcriptional regulator Transcription 56421489 Common - thioredoxin reductase GK2954 248 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 56419622 Common - hypothetical protein GK1087 19 COG2322 COG2322, Predicted membrane protein Function unknown 56421750 Common - D-lactate dehydrogenase GK3215 202 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 56421681 Common comFC late competence protein GK3146 158 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 56420342 Common - cobalt transporter system (permease) GK1807 29 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 161551797 Common rbfA ribosome-binding factor A GK1265 198 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 56419954 Common - hypothetical protein GK1419 74 COG1953 FUI1, Cytosine/uracil/thiamine/allantoin permeases Nucleotide transport and metabolism / Coenzyme metabolism 56420632 Common - hypothetical protein GK2097 3 None None None 56420754 Common - hypothetical protein GK2219 2 None None None 56420235 Nonpathogen - hypothetical protein GK1700 2 None None None 56420217 Nonpathogen - hypothetical protein GK1682 1 None None None 56421928 Common - acyl-CoA dehydrogenase GK3393 169 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 56420776 Common - hypothetical protein GK2241 3 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 56420378 Nonpathogen - hypothetical protein GK1843 1 None None None 56420171 Nonpathogen - hypothetical protein GK1636 5 COG2105 COG2105, Uncharacterized conserved protein Function unknown 56420197 Common - branched-chain amino acid ABC transporter (ATP-binding protein) GK1662 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 56419857 Common - hypothetical protein GK1322 133 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 56418679 Common - spore germination protein GK0144 3 None None None 56419586 Common - hypothetical protein GK1051 9 None None None 56418955 Common - transporter GK0420 133 COG1295 Rbn, Predicted membrane protein Function unknown 56419940 Common - hypothetical protein GK1405 105 COG0393 COG0393, Uncharacterized conserved protein Function unknown 56418686 Common - hypothetical protein GK0151 3 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 56419636 Common - hypothetical protein GK1101 126 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 56420358 Nonpathogen - hypothetical protein GK1823 1 None None None 56418550 Nonpathogen - hypothetical protein GK0015 6 None None None 56420042 Common - hypothetical protein GK1507 8 None None None 56419363 Common - hypothetical protein GK0828 3 None None None 56419161 Common - thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein GK0626 216 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 56419698 Common - fibronectin/fibrinogen-binding protein GK1163 87 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 56419998 Common - hypothetical protein GK1463 186 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 56419665 Common - hypothetical protein GK1130 182 COG1496 COG1496, Uncharacterized conserved protein Function unknown 56420749 Common folE GTP cyclohydrolase I GK2214 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 56421256 Common dnaI primosomal protein DnaI GK2721 71 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 56420228 Nonpathogen - hypothetical protein GK1693 1 None None None 56419347 Common - oligopeptide ABC transporter (permease) GK0812 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 56419488 Common mtnW 2,3-diketo-5-methylthiopentyl-1-phosphate enolase GK0953 64 COG1850 RbcL, Ribulose 1,5-bisphosphate carboxylase, large subunit Carbohydrate transport and metabolism 56419134 Common - integrase (resolvase family) GK0599 70 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 56421963 Common acpD azoreductase GK3428 98 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 56420007 Common - hypothetical protein GK1472 10 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 56420997 Common - phosphate ABC transporter (permease) GK2462 226 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 56420161 Common - spore germination protein GK1626 15 None None None 56420436 Common - transcriptional regulator involved in degradation (LacI family) GK1901 128 COG1609 PurR, Transcriptional regulators Transcription 56420972 Common - hypothetical protein GK2437 3 None None None 56421112 Common - D-tyrosyl-tRNA deacylase GK2577 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 56420279 Common - hypothetical protein GK1744 61 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 56418718 Common - hypothetical protein GK0183 10 None None None 56420112 Common - hypothetical protein GK1577 2 None None None 56420941 Common spoIIIAC stage III sporulation protein AC GK2406 15 None None None 56421511 Common - branched-chain amino acid ABC transporter (ATP-binding protein) GK2976 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 56420339 Common - hypothetical protein GK1804 81 COG2138 COG2138, Uncharacterized conserved protein Function unknown 56419054 Common - phage associated-antirepressor GK0519 41 COG3617 COG3617, Prophage antirepressor Transcription 56421075 Common - cystathionine beta-lyase GK2540 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 56418876 Common - putative lipid kinase GK0341 118 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 56419439 Common - multicopper oxidase GK0904 136 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 56420778 Common recQ ATP-dependent DNA helicase GK2243 229 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 56419104 Common - inosine-5-monophosphate dehydrogenase GK0569 219 COG0517 COG0517, FOG: CBS domain General function prediction only 56419974 Nonpathogen - hypothetical protein GK1439 1 None None None 56420286 Common - DNA topoisomerase IV subunit B GK1751 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 56419904 Common - hypothetical protein GK1369 20 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 56421542 Common - acetyl-CoA acetyltransferase GK3007 186 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 56421691 Common - hypothetical protein GK3156 46 COG2385 SpoIID, Sporulation protein and related proteins Cell division and chromosome partitioning 56420137 Common - enoyl-CoA hydratase GK1602 188 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 56420874 Nonpathogen - hypothetical protein GK2339 3 COG3391 COG3391, Uncharacterized conserved protein Function unknown 56421487 Common - hypothetical protein GK2952 89 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 56420603 Common - hypothetical protein GK2068 180 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 56421070 Common - sporulation sigma factor SigK GK2535 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 56419844 Nonpathogen - hypothetical protein GK1309 1 None None None 56419184 Common - phosphoserine aminotransferase GK0649 120 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 56420071 Common - transcriptional regulator (IclR family) GK1536 124 COG1414 IclR, Transcriptional regulator Transcription 56420517 Common - hypothetical protein GK1982 119 COG2353 COG2353, Uncharacterized conserved protein Function unknown 56419778 Common cheW chemotaxis signal transduction protein GK1243 128 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 56421735 Nonpathogen - hypothetical protein GK3200 1 None None None 56420918 Common - sigma-L-dependent transcriptional regulator GK2383 185 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 56421128 Common - bypass-of-forespore protein C (forespore regulator of the sigma-K checkpoint) GK2593 2 None None None 56421668 Common - carbon storage regulator GK3133 83 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 56421782 Common - potassium-transporting ATPase subunit B GK3247 232 COG2216 KdpB, High-affinity K+ transport system, ATPase chain B Inorganic ion transport and metabolism 56418768 Common - hypothetical protein GK0233 57 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 56421523 Nonpathogen - hypothetical protein GK2988 1 None None None 56421917 Common rho transcription termination factor Rho GK3382 209 COG1158 Rho, Transcription termination factor Transcription 56418597 Common - cell-division protein and general stress protein (class III heat-shock) GK0062 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 56419304 Common - molybdenum binding-protein-dependent transport system (permease) GK0769 199 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 56420233 Common - hypothetical protein GK1698 57 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 56420744 Common ndk nucleoside diphosphate kinase GK2209 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 56420807 Common - two-component response regulator GK2272 164 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 56421369 Nonpathogen - hypothetical protein GK2834 1 None None None 56420133 Common - acyl-CoA synthetase GK1598 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 56420955 Common - lipoate protein ligase GK2420 74 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 56421258 Common - hypothetical protein GK2723 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 56421935 Nonpathogen - hypothetical protein GK3400 2 COG4317 COG4317, Uncharacterized protein conserved in bacteria Function unknown 56419145 Common - hypothetical protein GK0610 89 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 56420512 Common glnH glutamine ABC transporter (glutamine-binding protein) GK1977 188 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 56420040 Common - acyl-CoA synthetase GK1505 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 56418691 Common - hypothetical protein GK0156 2 None None None 56419291 Common - hypothetical protein GK0756 9 None None None 56419258 Common - spermidine/putrescine ABC transporter (ATP-binding protein) GK0723 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 56420800 Common - ferric ion ABC transporter (permease) GK2265 190 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 56421178 Common - delta-aminolevulinic acid dehydratase GK2643 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 56421836 Common - transposase GK3301 96 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 56420250 Common - diaminobutyrate-2-oxoglutarate transaminase GK1715 118 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 56419327 Common - acetylglutamate kinase GK0792 219 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 56420779 Common - hypothetical protein GK2244 10 COG4955 COG4955, Uncharacterized protein conserved in bacteria Function unknown 56420509 Common - C4-dicarboxylate transport system (C4-dicarboxylate-binding protein) GK1974 112 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 56421756 Common - hypothetical protein GK3221 4 None None None 56421502 Common - hypothetical protein GK2967 14 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 56419039 Nonpathogen - hypothetical protein GK0504 1 None None None 56418556 Common - inhibitor of the pro-sigma K processing machinery GK0021 7 None None None 56421801 Common - hypothetical protein GK3266 73 COG3189 COG3189, Uncharacterized conserved protein Function unknown 56421346 Common - bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase GK2811 190 COG2876 AroA, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 56421362 Common - pullulanase GK2827 147 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 161551795 Common - dihydropyrimidinase GK1423 200 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 56421045 Common spoIIP stage II sporulation protein P (septal wall dissolution protein) GK2510 15 None None None 56421825 Nonpathogen - hypothetical protein GK3290 1 None None None 56419753 Common fliE flagellar hook-basal body protein FliE GK1218 80 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 56419746 Common topA DNA topoisomerase I GK1211 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 56419552 Common - hypothetical protein GK1017 66 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 56421632 Common - transporter GK3097 11 None None None 56418589 Common - hypothetical protein GK0054 11 None None None 56422016 Common - single-strand DNA-binding protein GK3481 216 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 56420511 Common glnQ glutamine ABC transporter (ATP-binding protein) GK1976 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 56419033 Nonpathogen - hypothetical protein GK0498 1 None None None 56419584 Common - tetrahydrodipicolinate succinylase GK1049 155 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 56421155 Nonpathogen - hypothetical protein GK2620 1 None None None 56418851 Common - coiled-coil protein GK0316 113 COG4372 COG4372, Uncharacterized protein conserved in bacteria with the myosin-like domain Function unknown 56419296 Nonpathogen - hypothetical protein GK0761 1 None None None 56419734 Common - hypothetical protein GK1199 11 None None None 56421121 Common yajC preprotein translocase subunit YajC GK2586 17 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 56420500 Common - hypothetical protein GK1965 69 COG1606 COG1606, ATP-utilizing enzymes of the PP-loop superfamily General function prediction only 56419721 Common - ATP-dependent DNA helicase GK1186 210 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 56419652 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase GK1117 208 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 56421860 Common - hypothetical protein GK3325 2 None None None 56420823 Common - superoxide dismutase GK2288 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 56418761 Common - ATP-dependent RNA helicase GK0226 242 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 56419690 Common - orotidine 5'-phosphate decarboxylase GK1155 159 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 56418807 Common - hypothetical protein GK0272 14 None None None 56419090 Nonpathogen - hypothetical protein GK0555 1 None None None 56418694 Common - transposase GK0159 148 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 56420711 Common - bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon GK2176 205 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 56421282 Common - hypothetical protein GK2747 78 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 56420416 Common xylF D-xylose ABC transporter (substrate-binding protein) GK1881 109 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 56418816 Common gatC aspartyl/glutamyl-tRNA amidotransferase subunit C GK0281 174 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 56421119 Common - stage V sporulation protein B (spore cortex synthesis) GK2584 28 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 56421652 Common - hypothetical protein GK3117 35 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 56418626 Common secE preprotein translocase subunit SecE GK0091 3 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 56421222 Common - electron transfer flavoprotein beta subunit GK2687 153 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 56420393 Common - PTS system, cellobiose-specific enzyme II, A component GK1858 31 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 56421559 Common - branched amino acid ABC transporter (permease) GK3024 157 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 56419793 Common polC DNA polymerase III PolC GK1258 219 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 56420109 Common - hypothetical protein GK1574 3 None None None 56420887 Common - hypothetical protein GK2352 96 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 56421030 Common - hypothetical protein GK2495 15 None None None 56418828 Common - transposase of IS231E-like element GK0293 11 None None None 56421624 Common racA polar chromosome segregation protein GK3089 2 COG0789 SoxR, Predicted transcriptional regulators Transcription 56419933 Common - hypothetical protein GK1398 6 COG5582 COG5582, Uncharacterized conserved protein Function unknown 56419221 Common gerPE spore germination protein GK0686 2 None None None 56419517 Common - hypothetical protein GK0982 2 None None None 56419048 Nonpathogen - hypothetical protein GK0513 1 None None None 56421678 Common - flagellar biosynthesis GK3143 70 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 56419189 Common - hypothetical protein GK0654 3 None None None 56419557 Nonpathogen - hypothetical protein GK1022 1 None None None 56420532 Common - repressor in the phenylacetic acid catabolism GK1997 33 COG3327 PaaX, Phenylacetic acid-responsive transcriptional repressor Transcription 56418617 Common ispF 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GK0082 187 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 56421469 Common - sporulation inhibitor KapD GK2934 17 COG5018 KapD, Inhibitor of the KinA pathway to sporulation, predicted exonuclease General function prediction only 56418766 Common - alanine racemase GK0231 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 56420984 Common - 5-formyltetrahydrofolate cyclo-ligase GK2449 68 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 56420869 Common - glucose-6-phosphate 1-dehydrogenase GK2334 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 56419878 Common - hypothetical protein GK1343 32 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 56419415 Common - IS1604-like transposase GK0880 88 None None None 56421588 Nonpathogen - hypothetical protein GK3053 7 COG3863 COG3863, Uncharacterized distant relative of cell wall-associated hydrolases Function unknown 56419430 Common - beta-propeller fold protein GK0895 103 COG3391 COG3391, Uncharacterized conserved protein Function unknown 56420689 Common - transcriptional antiterminator of glycerol uptake operon GK2154 26 COG1954 GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) Transcription 56419111 Common - transposase of IS654-like element GK0576 66 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 56420905 Common - methylmalonyl-CoA mutase GK2370 110 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 56420168 Common - hypothetical protein GK1633 113 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 56420467 Common ureA urease gamma subunit GK1932 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 56419522 Common - proton/sodium antiporter GK0987 198 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 56420677 Nonpathogen - hypothetical protein GK2142 1 None None None 56421272 Common - hypothetical protein GK2737 28 COG2707 COG2707, Predicted membrane protein Function unknown 56421385 Common - phosphoenolpyruvate carboxykinase GK2850 97 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 56419709 Common - hypothetical protein GK1174 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 56421065 Common motA flagellar motor protein MotA GK2530 122 COG1291 MotA, Flagellar motor component Cell motility and secretion 56421462 Common - general stress protein 13 GK2927 233 COG1098 VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) Translation, ribosomal structure and biogenesis 56419320 Nonpathogen - hypothetical protein GK0785 3 None None None 56421639 Common - hypothetical conserved protein in Tn5401 GK3104 23 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 56421580 Common - carboxylesterase GK3045 50 COG1647 COG1647, Esterase/lipase General function prediction only 56420694 Common - heat shock protein class I (low molecular weight) GK2159 6 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 56420879 Common - 6-phosphogluconate dehydrogenase GK2344 187 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 56418924 Nonpathogen - hypothetical protein GK0389 1 None None None 56422000 Common - glycerate kinase GK3465 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 56420262 Common - hypothetical protein GK1727 2 None None None 56422011 Common - replicative DNA helicase GK3476 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 56420664 Common sspH acid-soluble spore protein H GK2129 3 None None None 56421671 Common flgL flagellar hook-associated protein FlgL GK3136 108 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 56420942 Common spoIIIAB stage III sporulation protein SpoAB GK2407 5 None None None 56419635 Common - hypothetical protein GK1100 19 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 56421373 Common - hypothetical protein GK2838 45 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 56419895 Common glpK glycerol kinase GK1360 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 56419761 Common flgD flagellar basal body rod modification protein GK1226 87 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 56420480 Common - mannitol-1-phosphate 5-dehydrogenase GK1945 86 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 56421458 Common - hypothetical protein GK2923 3 None None None 56420355 Common - pyrazinamidase/nicotinamidase GK1820 103 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 56419545 Common - transposase GK1010 28 None None None 56421263 Common - formamidopyrimidine-DNA glycosylase GK2728 182 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 56419529 Nonpathogen - hypothetical protein GK0994 1 None None None 56421695 Common - hypothetical protein GK3160 12 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 56419088 Common - DNA segregation ATPase GK0553 196 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 56420125 Common - hypothetical protein GK1590 221 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 56421060 Common - hypothetical protein GK2525 28 COG1161 COG1161, Predicted GTPases General function prediction only 56419277 Common - nucleotide-binding protein GK0742 107 COG1666 COG1666, Uncharacterized protein conserved in bacteria Function unknown 56419942 Common - cation efflux transporter GK1407 200 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 56421395 Common - hypothetical protein GK2860 15 COG4824 COG4824, Phage-related holin (Lysis protein) General function prediction only 56418775 Common - ABC transporter (ATP-binding protein) GK0240 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 56419547 Common - transposase GK1012 18 COG5421 COG5421, Transposase DNA replication, recombination, and repair 56419684 Common pyrB aspartate carbamoyltransferase catalytic subunit GK1149 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 56418880 Common - transposase of IS654-like element GK0345 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 56419535 Common - hypothetical protein GK1000 2 None None None 56421008 Common - hypothetical protein GK2473 3 None None None 56420142 Common - multidrug resistance protein GK1607 207 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 56421039 Common - chaperone protein (heat shock protein 70) (HSP70) GK2504 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 56421784 Nonpathogen - hypothetical protein GK3249 1 None None None 56418789 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein GK0254 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 56419466 Nonpathogen - hypothetical protein GK0931 1 None None None 56419949 Nonpathogen - hypothetical protein GK1414 2 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 56419956 Common - putative oxidoreductase GK1421 226 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 56420727 Common qcrA menaquinol-cytochrome c reductase iron-sulfur subunit (Rieske iron-sulfur protein) GK2192 46 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 56420487 Common - alcohol dehydrogenase GK1952 177 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 56418821 Nonpathogen - lantibiotic precursor GK0286 1 None None None 56421888 Common - NADH dehydrogenase subunit D GK3353 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 56418606 Common - 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase (2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase) GK0071 202 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 56419510 Common - aluminum resistance protein GK0975 176 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 56419081 Nonpathogen - hypothetical protein GK0546 1 COG2319 COG2319, FOG: WD40 repeat General function prediction only 56419668 Common - hypothetical protein GK1133 68 COG0762 COG0762, Predicted integral membrane protein Function unknown 56419192 Common - Hit-like protein (cell-cycle regulation histidine triad) GK0657 239 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 56421407 Common - O-succinylbenzoic acid--CoA ligase GK2872 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 56418637 Common rpsG 30S ribosomal protein S7 GK0102 249 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 56419384 Nonpathogen - hypothetical protein GK0849 1 None None None 56421451 Common - hypothetical protein GK2916 69 COG1285 SapB, Uncharacterized membrane protein Function unknown 56419284 Common - cadmium efflux system accessory protein (cadmium-binding protein) GK0749 139 COG0640 ArsR, Predicted transcriptional regulators Transcription 56420292 Common - hypothetical protein GK1757 40 COG3647 COG3647, Predicted membrane protein Function unknown 56420585 Common - hypothetical protein GK2050 71 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 56421996 Common - amino acid transporter GK3461 176 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 56419825 Common - hypothetical protein GK1290 7 None None None 56420088 Common - hypothetical protein GK1553 23 COG1159 Era, GTPase General function prediction only 56420536 Nonpathogen - hypothetical protein GK2001 1 None None None 56421883 Common - NADH dehydrogenase subunit K GK3348 131 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 56420081 Common - cytochrome c oxidase (b(o/a)3-type) chain I GK1546 140 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 56421763 Common - ribose ABC transporter (ATP-binding protein) GK3228 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 56418758 Common ddl D-alanyl-alanine synthetase A GK0223 210 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 56419688 Common pyrK dihydroorotate dehydrogenase electron transfer subunit GK1153 74 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 56418824 Nonpathogen - hypothetical protein GK0289 1 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 56421422 Nonpathogen - hypothetical protein GK2887 1 None None None 56420739 Common trpE anthranilate synthase component I GK2204 223 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 56418995 Common - hypothetical protein GK0460 5 COG5609 COG5609, Uncharacterized conserved protein Function unknown 56421338 Common tyrS tyrosyl-tRNA synthetase GK2803 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 56418624 Common - RNA polymerase factor sigma-70 GK0089 98 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 56419435 Common - cytochrome c biogenesis protein (holocytochrome-c synthase) GK0900 150 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 56421597 Common clpP ATP-dependent Clp protease proteolytic subunit GK3062 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 56420705 Common dnaD chromosome replication initiation protein GK2170 19 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 56421383 Common - hypothetical protein GK2848 186 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 56418943 Common - hypothetical protein GK0408 5 None None None 56420785 Common - transposase GK2250 58 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 56420588 Common - hypothetical protein GK2053 8 None None None 56421524 Common - transposase GK2989 18 COG5421 COG5421, Transposase DNA replication, recombination, and repair 56420924 Common - DNA repair protein (recombination protein N) GK2389 201 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 56419806 Common - processing protease GK1271 202 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 56419715 Nonpathogen spoVM stage V sporulation protein M (spore cortex and coat synthesis) GK1180 2 None None None 56419071 Common - hypothetical protein GK0536 10 None None None 56419674 Nonpathogen - hypothetical protein GK1139 1 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 56420369 Common - hypothetical protein GK1834 131 COG0432 COG0432, Uncharacterized conserved protein Function unknown 56421032 Common rpsU 30S ribosomal protein S21 GK2497 99 None None None 56420426 Common iolD myo-inositol catabolism protein (thiamine pyrophosphate-requiring enzyme) GK1891 221 COG3962 COG3962, Acetolactate synthase Amino acid transport and metabolism 56421876 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase GK3341 215 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 56420308 Common - threonine dehydratase GK1773 213 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 56421614 Common - pyrophosphatase PpaX GK3079 205 COG0546 Gph, Predicted phosphatases General function prediction only 56419398 Common - hypothetical protein GK0863 76 COG2153 ElaA, Predicted acyltransferase General function prediction only 56421358 Common - hypothetical protein GK2823 178 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 56419880 Common - hypothetical protein GK1345 2 None None None 56421188 Common tig trigger factor GK2653 213 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 56421183 Nonpathogen - hypothetical protein GK2648 1 None None None 56419365 Common ppnK inorganic polyphosphate/ATP-NAD kinase GK0830 228 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 56421807 Common - sugar ABC transporter (permease) GK3272 142 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 56420504 Common - dihydroxy-acid dehydratase GK1969 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 56419961 Common - aldehyde dehydrogenase GK1426 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 56419923 Common - hypothetical protein GK1388 18 COG5421 COG5421, Transposase DNA replication, recombination, and repair 56421351 Common - DNA translocase (stage III sporulation protein E) GK2816 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 56419719 Common - L-serine dehydratase (L-serine deaminase) beta chain GK1184 166 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 56420752 Common spoIVA stage IV sporulation protein A (spore cortex formation and coat assembly) GK2217 15 None None None 56421020 Common - hypothetical protein GK2485 34 COG0517 COG0517, FOG: CBS domain General function prediction only 56420978 Common - hypothetical protein GK2443 9 COG4483 COG4483, Uncharacterized protein conserved in bacteria Function unknown 56419078 Common - hypothetical protein GK0543 25 COG5301 COG5301, Phage-related tail fibre protein General function prediction only 56420982 Nonpathogen - hypothetical protein GK2447 1 None None None 56419294 Nonpathogen - hypothetical protein GK0759 1 None None None 56419426 Common - transcriptional regulator (LysR family) GK0891 193 COG0583 LysR, Transcriptional regulator Transcription 56419440 Common - hypothetical protein GK0905 5 COG4990 COG4990, Uncharacterized protein conserved in bacteria Function unknown 56418793 Common - phosphoribosylaminoimidazole carboxylase ATPase subunit GK0258 193 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 56418786 Common - methanol dehydrogenase regulatory protein (MoxR protein) GK0251 182 COG0714 COG0714, MoxR-like ATPases General function prediction only 56421738 Nonpathogen - hypothetical protein GK3203 1 None None None 56420477 Common - transcriptional regulator (LacI family) GK1942 129 COG1609 PurR, Transcriptional regulators Transcription 56419116 Common - cation efflux transporter GK0581 210 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 56419375 Common - NDP-sugar dehydrogenase GK0840 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 56419760 Common - hypothetical protein GK1225 5 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 56421650 Common - flagellar protein FlaG GK3115 9 COG1334 FlaG, Uncharacterized flagellar protein FlaG Cell motility and secretion 56418545 Common - serine-type D-Ala-D-Ala carboxypeptidase GK0010 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 56420842 Common - stage V sporulation protein AA GK2307 4 None None None 56419264 Common - transcriptional regulator GK0729 222 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 56419485 Common mtnK methylthioribose kinase GK0950 29 COG4857 COG4857, Predicted kinase General function prediction only 56420077 Nonpathogen - hypothetical protein GK1542 1 None None None 56419232 Common - hypothetical protein GK0697 5 None None None 56419171 Common - hypothetical protein GK0636 6 None None None 56419388 Common - stage V sporulation protein AC GK0853 15 None None None 56421161 Nonpathogen - hypothetical protein GK2626 1 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 56420418 Common - transposase GK1883 14 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 56419337 Common - hypothetical protein GK0802 2 COG2267 PldB, Lysophospholipase Lipid metabolism 56421789 Common - NDP-suger dehydrogenase GK3254 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 56419959 Nonpathogen - hypothetical protein GK1424 1 None None None 56421813 Nonpathogen - hypothetical protein GK3278 1 None None None 56418680 Common - transposase GK0145 18 COG5421 COG5421, Transposase DNA replication, recombination, and repair 56420608 Common - SAM-dependent methyltransferase GK2073 176 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 56420317 Common - hypothetical protein GK1782 10 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 56420883 Nonpathogen - hypothetical protein GK2348 1 None None None 56421775 Common - hypothetical protein GK3240 27 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 56420859 Nonpathogen - hypothetical protein GK2324 1 None None None 56419458 Common - hypothetical protein GK0923 23 COG3610 COG3610, Uncharacterized conserved protein Function unknown 56420994 Common - hypothetical protein GK2459 3 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 56420590 Nonpathogen - hypothetical protein GK2055 1 None None None 56421944 Common - 4-oxalocrotonate tautomerase GK3409 34 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 56418557 Common - hypothetical protein GK0022 3 None None None 56420638 Common - hypothetical protein GK2103 41 COG4336 COG4336, Uncharacterized conserved protein Function unknown 56422027 Common gidB glucose-inhibited division protein B GK3492 199 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 56420581 Common ilvD dihydroxy-acid dehydratase GK2046 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 56418959 Common - hypothetical protein GK0424 3 None None None 56421643 Common - hypothetical protein GK3108 40 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 56421303 Nonpathogen - hypothetical protein GK2768 3 None None None 56419819 Common - ABC transporter (ATP-binding protein) GK1284 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 56419918 Common - hypothetical protein GK1383 226 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 56420163 Nonpathogen - hypothetical protein GK1628 1 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 56420732 Common tyrA prephenate dehydrogenase GK2197 160 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 56421892 Common atpC F0F1 ATP synthase subunit epsilon GK3357 174 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 56419408 Nonpathogen - hypothetical protein GK0873 1 None None None 56420411 Common - transposase GK1876 17 COG5421 COG5421, Transposase DNA replication, recombination, and repair 56419851 Common - acyl-CoA dehydrogenase GK1316 166 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 56419835 Common - hypothetical protein GK1300 103 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 56421512 Common - branched-chain amino acid ABC transporter (ATP-binding protein) GK2977 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 56421213 Common - hypothetical protein GK2678 3 None None None 56419400 Common - hypothetical protein GK0865 23 COG2382 Fes, Enterochelin esterase and related enzymes Inorganic ion transport and metabolism 56418566 Common - methionyl-tRNA synthetase (methionine--tRNA ligase) GK0031 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 56421566 Common - hypothetical protein GK3031 157 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 56421455 Common - phosphinothricin N-acetyltransferase GK2920 128 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 56421475 Nonpathogen - hypothetical protein GK2940 1 None None None 56421605 Common - bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein GK3070 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 56421849 Common - hypothetical protein GK3314 37 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 56418934 Common - cell-shape determining protein GK0399 224 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 56419983 Common - hypothetical protein GK1448 3 None None None 56420043 Common - hypothetical protein GK1508 140 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 56421410 Common - 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase GK2875 100 COG1165 MenD, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase Coenzyme metabolism 56420283 Common - hypothetical protein GK1748 5 COG0789 SoxR, Predicted transcriptional regulators Transcription 56421823 Common - hypothetical protein GK3288 202 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 56419564 Common - gluconate 5-dehydrogenase GK1029 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 56419861 Common glnR transcriptional repressor of glutamine synthetase GK1326 78 COG0789 SoxR, Predicted transcriptional regulators Transcription 56419451 Common - hypothetical protein GK0916 22 COG1659 COG1659, Uncharacterized protein, linocin/CFP29 homolog Function unknown 56419483 Common - ribose ABC transporter (substrate-binding protein) GK0948 92 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 56420552 Common - hypothetical protein GK2017 24 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 56421649 Common fliD flagellar capping protein GK3114 75 COG1345 FliD, Flagellar capping protein Cell motility and secretion 56420018 Common - hypothetical protein GK1483 153 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 56420201 Common - hypothetical protein GK1666 11 None None None 56419381 Nonpathogen - hypothetical protein GK0846 2 None None None 56420892 Nonpathogen - hypothetical protein GK2357 1 None None None 56420030 Common - hypothetical protein GK1495 32 COG3011 COG3011, Uncharacterized protein conserved in bacteria Function unknown 56421552 Common - dethiobiotin synthetase GK3017 128 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 56420833 Common - peptidyl-prolyl cis-trans isomerase (rotamase) GK2298 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 56420380 Nonpathogen - hypothetical protein GK1845 1 COG2336 MazE, Growth regulator Signal transduction mechanisms 56420526 Common - hypothetical protein GK1991 223 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 56419476 Nonpathogen - hypothetical protein GK0941 1 None None None 56419210 Common - manganese oxidation GK0675 101 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 56420626 Common - hypothetical protein GK2091 244 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 56418663 Common - methionine aminopeptidase GK0128 249 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 56419590 Nonpathogen - hypothetical protein GK1055 1 None None None 56420219 Common - 3-oxoacyl-[acyl-carrier protein] reductase (3-ketoacyl-[acyl carrier protein] reductase) GK1684 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 56419702 Common gmk guanylate kinase GK1167 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 56421316 Common - acyl-CoA dehydrogenase GK2781 130 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 56419782 Nonpathogen - hypothetical protein GK1247 1 None None None 56420634 Common - hypothetical protein GK2099 116 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 56419624 Common - hypothetical protein GK1089 3 None None None 56421838 Common - transposase GK3303 18 COG5421 COG5421, Transposase DNA replication, recombination, and repair 56419086 Common - hypothetical protein GK0551 2 COG1476 COG1476, Predicted transcriptional regulators Transcription 56421480 Common - low-affinity inorganic phosphate transporter GK2945 170 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 56418879 Common - type I restriction-modification system S subunit GK0344 77 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 56418952 Nonpathogen - hypothetical protein GK0417 1 None None None 56419748 Common clpQ ATP-dependent protease peptidase subunit GK1213 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 56420259 Nonpathogen - hypothetical protein GK1724 1 None None None 56418930 Common - glycolate oxidase GK0395 169 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 56419988 Common - hypothetical protein GK1453 63 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 56420867 Common - NADH-dependent flavin oxidoreductase GK2332 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 56420199 Common - branched-chain amino acid ABC transporter (substrate-binding protein) GK1664 123 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 56421443 Common - hypothetical protein GK2908 2 COG3680 COG3680, Uncharacterized protein conserved in bacteria Function unknown 56418552 Common dnaX DNA-directed DNA polymerase III gamma and tau subunits GK0017 248 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 56420657 Common - ABC transporter (permease) GK2122 190 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 161551799 Common prs ribose-phosphate pyrophosphokinase GK0044 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 56419710 Common - serine/threonine phosphatase GK1175 139 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 56420432 Common - oxidoreductase GK1897 191 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 56421117 Common secDF bifunctional preprotein translocase subunit SecD/SecF GK2582 221 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 56419952 Nonpathogen - hypothetical protein GK1417 1 None None None 56419822 Common - hypothetical protein GK1287 146 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 56421810 Common - transcriptional regulator (lacI family) GK3275 126 COG1609 PurR, Transcriptional regulators Transcription 56420721 Common - hypothetical protein GK2186 25 COG1694 MazG, Predicted pyrophosphatase General function prediction only 56419663 Common sigG sporulation sigma factor SigG GK1128 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 56421029 Common - stage IV sporulation protein GK2494 15 None None None 56421397 Nonpathogen - hypothetical protein GK2862 1 None None None 56418967 Common - hypothetical protein GK0432 8 COG4758 COG4758, Predicted membrane protein Function unknown 56418957 Common - multidrug-efflux transporter GK0422 140 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 56422009 Common - two-component response regulator GK3474 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 56422022 Common - hypothetical protein GK3487 14 None None None 56419349 Common - oligopeptide ABC transporter (ATP-binding protein) GK0814 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 56419318 Common - hypothetical protein GK0783 71 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 56421138 Common - hypothetical protein GK2603 15 COG1827 COG1827, Predicted small molecule binding protein (contains 3H domain) General function prediction only 56418862 Nonpathogen - hypothetical protein GK0327 1 None None None 56420067 Common - glycolate oxidase subunit GK1532 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 56419993 Nonpathogen - hypothetical protein GK1458 1 None None None 56420107 Common - hypothetical protein GK1572 2 None None None 56419765 Common fliM flagellar motor switch protein FliM GK1230 107 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 56420148 Common - hypothetical protein GK1613 4 None None None 56421547 Common - hypothetical protein GK3012 9 COG5577 COG5577, Spore coat protein Cell envelope biogenesis, outer membrane 56421205 Common - transcriptional regulator GK2670 133 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 56421191 Common - isopropylmalate isomerase large subunit GK2656 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 56421741 Common - ABC transporter (permease) GK3206 154 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 56418670 Common - ABC transporter (ATP-binding protein) GK0135 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 56420310 Common - dihydrofolate reductase GK1775 148 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 56421635 Common - cell-division protein GK3100 120 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 56418855 Common - hypothetical protein GK0320 13 None None None 56421108 Common hisS histidyl-tRNA synthetase GK2573 249 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 56419217 Common - ATP-dependent deoxyribonuclease subunit A GK0682 227 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 56419324 Nonpathogen - hypothetical protein GK0789 1 None None None 56421518 Common - hypothetical protein GK2983 128 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 56419758 Common fliJ flagellar biosynthesis chaperone GK1223 2 COG2882 FliJ, Flagellar biosynthesis chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 56421428 Common - N-methylhydantoinase B (ATP-hydrolyzing) GK2893 95 COG0146 HyuB, N-methylhydantoinase B/acetone carboxylase, alpha subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 56420860 Common - hypothetical protein GK2325 2 None None None 56421796 Common - hypothetical protein GK3261 3 COG4715 COG4715, Uncharacterized conserved protein Function unknown 56418655 Common rpsH 30S ribosomal protein S8 GK0120 249 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 56420794 Common - hypothetical protein GK2259 109 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 56420652 Common - acetyl transferase GK2117 23 COG0456 RimI, Acetyltransferases General function prediction only 56420325 Nonpathogen - hypothetical protein GK1790 1 None None None 56419043 Nonpathogen - hypothetical protein GK0508 1 None None None 56421408 Common - naphthoate synthase GK2873 178 COG0447 MenB, Dihydroxynaphthoic acid synthase Coenzyme metabolism 56420816 Common - cytochrome c biogenesis protein GK2281 53 COG1333 ResB, ResB protein required for cytochrome c biosynthesis Posttranslational modification, protein turnover, chaperones 56418887 Common - cadmium-transporting ATPase GK0352 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 56421855 Common - UTP-glucose-1-phosphate uridylyltransferase GK3320 234 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 56420348 Common - ribonuclease activity regulator protein RraA GK1813 85 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 56421725 Common - transcriptional regulator GK3190 41 COG1396 HipB, Predicted transcriptional regulators Transcription 56421745 Common - sugar ABC transporter (sugar-binding protein) GK3210 105 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 56420159 Common - spore germination protein GK1624 15 None None None 56421951 Common - putative heme peroxidase GK3416 34 COG3253 COG3253, Uncharacterized conserved protein Function unknown 56420625 Common - hypothetical protein GK2090 100 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 56419919 Nonpathogen - hypothetical protein GK1384 2 None None None 56421296 Common - hypothetical protein GK2761 48 COG0439 AccC, Biotin carboxylase Lipid metabolism 56421003 Common - hypothetical protein GK2468 9 COG5663 COG5663, Uncharacterized conserved protein Function unknown 56420236 Nonpathogen - hypothetical protein GK1701 1 None None None 56421094 Common - hypothetical protein GK2559 11 None None None 56418644 Common rplB 50S ribosomal protein L2 GK0109 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 56418905 Common - thiamine biosynthesis protein ThiC GK0370 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 56421466 Common - aminotransferase GK2931 236 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 56419100 Common - ribosomal large subunit pseudouridine synthase GK0565 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 56420097 Common - hypothetical protein GK1562 128 COG0824 FcbC, Predicted thioesterase General function prediction only 56420566 Common pdh phenylalanine dehydrogenase GK2031 159 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 56421737 Common - transcriptional regulator (TetR/AcrR family) GK3202 139 COG1309 AcrR, Transcriptional regulator Transcription 56420057 Nonpathogen - hypothetical protein GK1522 1 None None None 56421492 Common dapF diaminopimelate epimerase GK2957 199 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 56418975 Nonpathogen - hypothetical protein GK0440 1 None None None 56419619 Common ctaE cytochrome c oxidase subunit III GK1084 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 56418554 Common recR recombination protein RecR GK0019 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 56420155 Common - transcriptional regulator (GntR family) GK1620 105 COG1725 COG1725, Predicted transcriptional regulators Transcription 56419163 Common - hypothetical protein GK0628 220 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 56420746 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase GK2211 225 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 56420364 Common hemD uroporphyrinogen-III synthase GK1829 42 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 56419574 Common - hypothetical protein GK1039 215 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 56421271 Common - methylcitrate synthase GK2736 194 COG0372 GltA, Citrate synthase Energy production and conversion 56420620 Common - hypothetical protein GK2085 18 None None None 56420144 Nonpathogen - hypothetical protein GK1609 1 None None None 56418812 Common - hypothetical protein GK0277 9 COG4851 CamS, Protein involved in sex pheromone biosynthesis General function prediction only 56420761 Common - 1-acylglycerol-3-phosphate O-acyltransferase GK2226 149 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 56422018 Common - translation-associated GTPase GK3483 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 56420090 Common - hypothetical protein GK1555 2 None None None 56421171 Common - hypothetical protein GK2636 31 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 56421176 Common - hypothetical protein GK2641 4 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 56421347 Common - hypothetical protein GK2812 9 None None None 56418560 Common - DNA polymerase III subunit delta' GK0025 216 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 56418692 Common - hypothetical protein GK0157 63 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 56418742 Common - hypothetical protein GK0207 188 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 56419576 Common - hypothetical protein GK1041 133 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 56419599 Common - hypothetical protein GK1064 2 None None None 56419092 Common - hypothetical protein GK0557 2 COG1609 PurR, Transcriptional regulators Transcription 56418870 Common - transposase GK0335 96 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 56420802 Common - transposase GK2267 30 None None None 56420226 Common - hypothetical protein GK1691 46 COG0398 COG0398, Uncharacterized conserved protein Function unknown 56421545 Common - proline dehydrogenase GK3010 139 COG0506 PutA, Proline dehydrogenase Amino acid transport and metabolism 56421718 Nonpathogen - hypothetical protein GK3183 1 None None None 56419256 Nonpathogen - hypothetical protein GK0721 2 COG1300 SpoIIM, Uncharacterized membrane protein Function unknown 56420654 Nonpathogen - hypothetical protein GK2119 1 None None None 56418814 Common - hypothetical protein GK0279 15 None None None 56420446 Common - two-component response regulator GK1911 156 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 56421158 Nonpathogen - hypothetical protein GK2623 1 None None None 56419490 Common mtnB methylthioribulose-1-phosphate dehydratase GK0955 42 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 56420502 Common - hypothetical protein GK1967 114 COG3970 COG3970, Fumarylacetoacetate (FAA) hydrolase family protein General function prediction only 56421500 Common - 2-hydroxyacid dehydrogenase GK2965 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 56420615 Common - cytochrome c biogenesis protein GK2080 100 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 56420956 Common - hypothetical protein GK2421 171 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 56421703 Common - pleiotropic regulatory protein GK3168 199 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 56419032 Nonpathogen - hypothetical protein GK0497 1 None None None 56421340 Common - hypothetical protein GK2805 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 56418711 Nonpathogen - hypothetical protein GK0176 1 None None None 56418831 Nonpathogen - hypothetical protein GK0296 1 None None None 56419037 Nonpathogen - hypothetical protein GK0502 1 None None None 56421449 Common tgl transglutaminase GK2914 4 None None None 56418791 Common - small heat shock protein GK0256 18 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 56419199 Common - transcriptional regulator (TetR/AcrR family) GK0664 138 COG1309 AcrR, Transcriptional regulator Transcription 56421554 Common - pyruvate kinase GK3019 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 56419194 Common - ABC transporter (permease) GK0659 10 COG4473 EcsB, Predicted ABC-type exoprotein transport system, permease component Intracellular trafficking and secretion 56419638 Common - hypothetical protein GK1103 27 COG1323 COG1323, Predicted nucleotidyltransferase General function prediction only 56421863 Nonpathogen - hypothetical protein GK3328 1 None None None 56420713 Common panC pantoate--beta-alanine ligase GK2178 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 56421764 Common - ribose ABC transporter (permease) GK3229 44 COG1869 RbsD, ABC-type ribose transport system, auxiliary component Carbohydrate transport and metabolism 56420821 Common - D-alanyl-D-alanine carboxypeptidase GK2286 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 56421425 Common - hypothetical protein GK2890 230 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 56420051 Common - hypothetical protein GK1516 17 COG1284 COG1284, Uncharacterized conserved protein Function unknown 56419728 Common smc chromosome segregation ATPase (SMC) GK1193 180 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 56418703 Nonpathogen - hypothetical protein GK0168 1 None None None 56419057 Common - site-specific recombinase (phage integrase family) GK0522 20 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 56421654 Common - hypothetical protein GK3119 14 COG5421 COG5421, Transposase DNA replication, recombination, and repair 56419453 Common - UDP-N-acetylenolpyruvoylglucosamine reductase GK0918 207 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 56419378 Nonpathogen - hypothetical protein GK0843 1 None None None 56420999 Nonpathogen - hypothetical protein GK2464 1 None None None 56418603 Common - 4-amino-4-deoxychorismate lyase GK0068 187 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 56420540 Common - hypothetical protein GK2005 9 None None None 56419627 Common - hypothetical protein GK1092 3 None None None 56420323 Nonpathogen - hypothetical protein GK1788 1 None None None 56419251 Common - 5-methyltetrahydrofolate--homocysteine S-methyltransferase GK0716 179 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 56419651 Nonpathogen - hypothetical protein GK1116 2 None None None 56421224 Common - transcriptional regulator (TetR/AcrR family) GK2689 152 COG1309 AcrR, Transcriptional regulator Transcription 56419202 Common - hypothetical protein GK0667 110 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 56421915 Common - thymidine kinase GK3380 95 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 56420270 Nonpathogen rtp replication terminator protein GK1735 2 None None None 56419156 Common - hypothetical protein GK0621 41 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 56419644 Common - hypothetical protein GK1109 3 None None None 56419330 Common carB carbamoyl phosphate synthase large subunit GK0795 238 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 56421241 Common pheT phenylalanyl-tRNA synthetase subunit beta GK2706 237 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 56421923 Common - hypothetical protein GK3388 3 None None None 56421133 Common - hypothetical protein GK2598 8 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 56419106 Common - hypothetical protein GK0571 3 None None None 56419666 Common - hypothetical protein GK1131 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 56420181 Common - transposase GK1646 73 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 56421363 Common - hypothetical protein GK2828 3 None None None 56420188 Common - NAD-dependent deacetylase GK1653 152 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 56419046 Nonpathogen - hypothetical protein GK0511 1 None None None 56419056 Common - hypothetical protein GK0521 3 None None None 56421485 Common - hypothetical protein GK2950 3 None None None 56419329 Common - carbamoyl phosphate synthase small subunit GK0794 233 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 56421886 Nonpathogen - hypothetical protein GK3351 1 None None None 56420110 Common - hypothetical protein GK1575 2 None None None 56421711 Common - hypothetical protein GK3176 62 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 56421101 Common - hypothetical protein GK2566 8 COG2364 COG2364, Predicted membrane protein Function unknown 56419681 Common - hypothetical protein GK1146 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 56421662 Common - aminotransferase (degT family) GK3127 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 56419972 Common - NAD-dependent deacetylase GK1437 152 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 56420772 Nonpathogen - hypothetical protein GK2237 1 None None None 56420135 Common - acetyl-CoA carboxylase biotin carboxyl carrier protein subunit GK1600 197 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 56422002 Common - hypothetical protein GK3467 167 COG1576 COG1576, Uncharacterized conserved protein Function unknown 56419368 Common - stage V sporulation protein E GK0833 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 56419682 Common - pyrimidine regulatory protein PyrR GK1147 112 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 56420434 Common - oxidoreductase GK1899 186 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 56421626 Common - glycosyltransferase GK3091 155 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 56419550 Common - hypothetical protein GK1015 3 None None None 56419500 Common - hypothetical protein GK0965 26 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 56419543 Common - hypothetical protein GK1008 70 COG1959 COG1959, Predicted transcriptional regulator Transcription 56420814 Common - two-component response regulator GK2279 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 56421436 Common - ferrichrome ABC transporter (substrate-binding protein) GK2901 111 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 56421557 Common - branched chain amino acid ABC transporter (ATP-binding protein) GK3022 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 56420768 Common - L-asparaginase (L-asparagine amidohydrolase) GK2233 140 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 56421274 Common - pyruvate kinase GK2739 234 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 56419301 Common - nitrate/nitrite transporter GK0766 109 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 56420809 Common - hypothetical protein GK2274 48 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 56419429 Common - menaquinol-cytochrome c reductase iron-sulfur subunit GK0894 40 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 56421693 Nonpathogen - hypothetical protein GK3158 1 None None None 56420387 Common - hypothetical protein GK1852 61 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 56421110 Common - peroxiredoxin GK2575 218 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 56420123 Common - hypothetical protein GK1588 39 COG3342 COG3342, Uncharacterized conserved protein Function unknown 56420579 Common - ring-oxidation complex protein 1 (phenylacetic acid catabolism) GK2044 46 COG3396 COG3396, Uncharacterized conserved protein Function unknown 56418630 Common rplJ 50S ribosomal protein L10 GK0095 219 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 56421998 Common - Rieske [2Fe-2S] iron-sulfur protein GK3463 120 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 56420936 Common spoIIIAH stage III sporulation protein AH GK2401 8 None None None 56418543 Common - hypothetical protein GK0008 4 None None None 56420025 Common - transcriptional regulator (mercuric resistance operon regulatory protein) GK1490 144 COG0789 SoxR, Predicted transcriptional regulators Transcription 56418889 Common - sodium:alanine symporter GK0354 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 56418893 Common - sporulation control protein GK0358 21 COG4326 Spo0M, Sporulation control protein General function prediction only 56419873 Nonpathogen - hypothetical protein GK1338 1 None None None 56420840 Common - stage V sporulation protein AC GK2305 15 None None None 56420264 Nonpathogen - hypothetical protein GK1729 1 None None None 56419527 Nonpathogen - hypothetical protein GK0992 1 None None None 56420960 Common gcvT glycine cleavage system aminomethyltransferase T GK2425 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 56421574 Common - hypothetical protein GK3039 92 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 56420855 Common - ADP-ribose pyrophosphatase GK2320 178 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 56419944 Common - sulfite reductase flavoprotein subunit GK1409 106 COG0369 CysJ, Sulfite reductase, alpha subunit (flavoprotein) Inorganic ion transport and metabolism 56421446 Common - IS1604-like transposase GK2911 81 None None None 56419322 Nonpathogen - hypothetical protein GK0787 1 None None None 56419776 Common cheB chemotaxis-specific methylesterase GK1241 213 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 56419143 Common - chaperone protein GK0608 148 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 56420551 Common ulaA ascorbate-specific PTS system enzyme IIC GK2016 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 56419445 Common - ABC transporter (ATP-binding protein) GK0910 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 56419979 Common - hypothetical protein GK1444 4 COG4640 COG4640, Predicted membrane protein Function unknown 56419372 Common - spore coat protein GK0837 6 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 56418721 Common - amino acid permease GK0186 161 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 56420001 Common - phosphoglycerate mutase GK1466 199 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 56420755 Common - NAD(P)H-dependent glycerol-3-phosphate dehydrogenase GK2220 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 56418608 Common - transcriptional regulator involved in nitrogen regulation (NifR3/Smm1 family) GK0073 209 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 56419751 Common flgB flagellar basal body rod protein FlgB GK1216 111 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 56419533 Nonpathogen - hypothetical protein GK0998 1 None None None 56420570 Common - acetyl-CoA acetyltransferase GK2035 186 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 56419395 Nonpathogen - hypothetical protein GK0860 1 None None None 56420497 Nonpathogen - urease accessory protein GK1962 16 None None None 56421682 Common comFA late competence protein GK3147 207 COG4098 comFA, Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein) DNA replication, recombination, and repair 56420587 Common - glycosyltransferase GK2052 139 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 56420489 Common - dehydrogenase GK1954 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 56419464 Common - hypothetical protein GK0929 13 COG3162 COG3162, Predicted membrane protein Function unknown 56418673 Common truA tRNA pseudouridine synthase A GK0138 236 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 56420294 Common - hypothetical protein GK1759 71 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 56420538 Common - hypothetical protein GK2003 38 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 56420213 Common - cytoplasmic trehalase (alpha,alpha-trehalose glucohydrolase) GK1678 32 COG1626 TreA, Neutral trehalase Carbohydrate transport and metabolism 56420247 Common - transposase of IS5377-like element GK1712 23 COG3385 COG3385, FOG: Transposase and inactivated derivatives DNA replication, recombination, and repair 56418639 Common tuf elongation factor Tu GK0104 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 56421088 Common - hypothetical protein GK2553 9 COG3906 COG3906, Uncharacterized protein conserved in bacteria Function unknown 56421265 Common polA DNA polymerase I GK2730 217 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 56419173 Common - hypothetical protein GK0638 6 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 56420337 Common - precorrin isomerase GK1802 119 COG2082 CobH, Precorrin isomerase Coenzyme metabolism 56419566 Common - transcriptional regulator (TetR/AcrR family) GK1031 148 COG1309 AcrR, Transcriptional regulator Transcription 56420173 Common - hypothetical protein GK1638 101 COG0730 COG0730, Predicted permeases General function prediction only 56418587 Common - hypothetical protein GK0052 61 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 56419432 Common - hypothetical protein GK0897 2 None None None 56421453 Common - hypothetical protein GK2918 15 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 56419604 Nonpathogen - hypothetical protein GK1069 1 None None None 56420240 Nonpathogen - hypothetical protein GK1705 6 None None None 56420395 Common - transcriptional regulator GK1860 20 COG0789 SoxR, Predicted transcriptional regulators Transcription 56420454 Common - aldehyde dehydrogenase GK1919 224 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 56418764 Common - hypothetical protein GK0229 4 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 56419223 Common gerPC spore germination protein GK0688 2 None None None 56419889 Common - hypothetical protein GK1354 2 None None None 56419124 Common - arsenate reductase GK0589 151 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 56419607 Common - hypothetical protein GK1072 2 None None None 56420697 Common - hypothetical protein GK2162 2 None None None 56420687 Common - alpha-galactosidase GK2152 46 COG3345 GalA, Alpha-galactosidase Carbohydrate transport and metabolism 56421676 Common - hypothetical protein GK3141 19 COG1728 COG1728, Uncharacterized protein conserved in bacteria Function unknown 56419209 Common - hypothetical protein GK0674 14 COG4392 COG4392, Predicted membrane protein Function unknown 56420903 Common - hypothetical protein GK2368 11 None None None 56420720 Common - dihydrodipicolinate reductase GK2185 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 56420104 Common - hypothetical protein GK1569 83 COG2509 COG2509, Uncharacterized FAD-dependent dehydrogenases General function prediction only 56420885 Common - lactoylglutathione lyase GK2350 117 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 56421027 Common - hypothetical protein GK2492 59 COG1480 COG1480, Predicted membrane-associated HD superfamily hydrolase General function prediction only 56421017 Common sigA RNA polymerase sigma factor RpoD GK2482 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 56419519 Common - short chain alcohol dehydrogenase GK0984 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 56418773 Common - ribosomal protein (S18)-alanine acetyltransferase GK0238 201 COG0456 RimI, Acetyltransferases General function prediction only 56418610 Common - transcriptional regulator GK0075 22 COG4463 CtsR, Transcriptional repressor of class III stress genes Transcription 56420277 Common - aminotransferase GK1742 207 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 56421619 Common - hypothetical protein GK3084 5 None None None 56421371 Common - hypothetical protein GK2836 170 COG2081 COG2081, Predicted flavoproteins General function prediction only 56420208 Common - hypothetical protein GK1673 10 None None None 56418848 Common - hypothetical protein GK0313 154 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 56421067 Common - hypothetical protein GK2532 20 COG0628 PerM, Predicted permease General function prediction only 56421686 Common - two-component sensor histidine kinase (degradative enzyme regulator / competence regulator) GK3151 151 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 56421378 Common - multidrug resistance protein GK2843 36 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 56419736 Common - tRNA (guanine-N(1)-)-methyltransferase (M1G-methyltransferase) GK1201 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 56418858 Common - D-aminopeptidase GK0323 47 COG3191 DmpA, L-aminopeptidase/D-esterase Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 56419520 Common - hypothetical protein GK0985 2 None None None 56419121 Common - hypothetical protein GK0586 8 COG4026 COG4026, Uncharacterized protein containing TOPRIM domain, potential nuclease General function prediction only 56418983 Common - hypothetical protein GK0448 2 None None None 56421164 Common - ATPase involved in pili biogenesis GK2629 210 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 56421942 Common - hypothetical protein GK3407 4 None None None 56419245 Common - thiamine pyrophosphate-dependent dehydrogenase, E1 component alpha subunit GK0710 154 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 56420662 Nonpathogen - hypothetical protein GK2127 18 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 56419020 Nonpathogen - hypothetical protein GK0485 1 None None None 56421328 Common - acetate-CoA ligase GK2793 223 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 56421295 Common - hypothetical protein GK2760 12 COG0640 ArsR, Predicted transcriptional regulators Transcription 56420935 Common - acetyl-CoA carboxylase biotin carboxyl carrier protein subunit GK2400 182 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 56419763 Common - hypothetical protein GK1228 26 COG1582 FlgEa, Uncharacterized protein, possibly involved in motility Cell motility and secretion 56421430 Common - hypothetical protein GK2895 131 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 56421612 Common hisZ ATP phosphoribosyltransferase regulatory subunit GK3077 248 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 56420881 Common - chemotaxis protein GK2346 121 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 56421582 Nonpathogen - hypothetical protein GK3047 1 None None None 56419874 Common - cytochrome c biogenesis protein GK1339 83 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 56420646 Common - hypothetical protein GK2111 37 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 56418926 Common - hypothetical protein GK0391 6 None None None 56419306 Common - hypothetical protein GK0771 46 COG2846 COG2846, Regulator of cell morphogenesis and NO signaling Cell division and chromosome partitioning 56421062 Common - hypothetical protein GK2527 2 None None None 56419897 Common - hypothetical protein GK1362 68 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 56420944 Common - hypothetical protein GK2409 4 None None None 56421218 Nonpathogen - hypothetical protein GK2683 1 None None None 56420837 Common - stage V sporulation protein AE GK2302 7 None None None 56419767 Common cheY two-component response regulator involved in modulation of flagellar GK1232 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 56420930 Common xseA exodeoxyribonuclease VII large subunit GK2395 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 56421895 Common - F0F1 ATP synthase subunit alpha GK3360 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 56421289 Nonpathogen - hypothetical protein GK2754 1 None None None 56421689 Common - hypothetical protein GK3154 185 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 56419828 Common pgsA CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (phosphatidylglycerophosphate synthase) (PGP synthase) GK1293 205 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 56420583 Common proB gamma-glutamyl kinase GK2048 193 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 56420858 Nonpathogen - hypothetical protein GK2323 1 None None None 56419340 Common - 3-oxoacyl-(acyl carrier protein) synthase II GK0805 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 56421636 Common - cell-division ATP-binding protein GK3101 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 56420669 Common - transcriptional regulator GK2134 179 COG0640 ArsR, Predicted transcriptional regulators Transcription 56419877 Common - hypothetical protein GK1342 3 None None None 56421059 Common aroE shikimate 5-dehydrogenase GK2524 225 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 56419102 Common - hypothetical protein GK0567 9 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 56420241 Nonpathogen - hypothetical protein GK1706 1 None None None 56421964 Nonpathogen - hypothetical protein GK3429 1 None None None 56421076 Common - cysteine synthase GK2541 221 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 56419097 Common - plant-metabolite dehydrogenase GK0562 194 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 56419677 Common - ABC transporter (ATP-binding protein) GK1142 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 56418779 Common - hypothetical protein GK0244 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 56419323 Common - transcriptional regulator (FNR/CRP family) GK0788 175 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 56419136 Common - hypothetical protein GK0601 2 None None None 56420439 Common araA L-arabinose isomerase GK1904 35 COG2160 AraA, L-arabinose isomerase Carbohydrate transport and metabolism 56420231 Common - hypothetical protein GK1696 38 COG3402 COG3402, Uncharacterized conserved protein Function unknown 56421323 Common - hypothetical protein GK2788 16 COG3874 COG3874, Uncharacterized conserved protein Function unknown 56420801 Common - ferric ion ABC transporter (ferric ion-binding protein) GK2266 183 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 56421660 Common - methionyl-tRNA formyltransferase GK3125 217 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 56418713 Common - hypothetical protein GK0178 112 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 56419890 Common - recombinase of Bh.Int-like element GK1355 97 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 56418986 Common - cell-division inhibitor GK0451 108 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 56420494 Common - hypothetical protein GK1959 68 COG2721 UxaA, Altronate dehydratase Carbohydrate transport and metabolism 56421388 Common - hypothetical protein GK2853 3 None None None 56419946 Common - aldehyde dehydrogenase GK1411 222 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 56420008 Common - hypothetical protein GK1473 13 COG2267 PldB, Lysophospholipase Lipid metabolism 56420759 Common - hypothetical protein GK2224 2 None None None 56421457 Common - potassium channel protein GK2922 17 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 56420023 Common - hypothetical protein GK1488 36 COG4587 COG4587, ABC-type uncharacterized transport system, permease component General function prediction only 56420964 Nonpathogen - hypothetical protein GK2429 1 None None None 56420524 Common - adenine deaminase GK1989 68 COG1001 AdeC, Adenine deaminase Nucleotide transport and metabolism 56418745 Common - intracellular alkaline serine protease GK0210 136 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 56421261 Common - glyceraldehyde-3-phosphate dehydrogenase GK2726 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 56420844 Common - anti-sigma F factor GK2309 45 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 56419205 Common - ABC transporter (permease) GK0670 47 COG4120 COG4120, ABC-type uncharacterized transport system, permease component General function prediction only 56419913 Common - hypothetical protein GK1378 55 COG1401 McrB, GTPase subunit of restriction endonuclease Defense mechanisms 56418997 Common - oxalate:formate antiporter GK0462 112 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 56418619 Common - serine O-acetyltransferase GK0084 215 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 56421821 Nonpathogen - hypothetical protein GK3286 2 None None None 56420238 Common - hypothetical protein GK1703 62 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 56420939 Common spoIIIAE stage III sporulation protein AE GK2404 15 None None None 56421150 Common mreD cell-shape determining protein GK2615 4 COG2891 MreD, Cell shape-determining protein Cell envelope biogenesis, outer membrane 56420831 Common - riboflavin synthase subunit alpha GK2296 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 56420175 Common - hypothetical protein GK1640 80 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 56421867 Common flhO flagellar basal-body rod protein GK3332 125 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 56421084 Common - protease GK2549 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 56420351 Common - transposase GK1816 58 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 56418612 Common - ATP:guanido phosphotransferase GK0077 25 COG3869 COG3869, Arginine kinase Amino acid transport and metabolism 56419542 Nonpathogen - hypothetical protein GK1007 1 None None None 56419970 Common - hypothetical protein GK1435 22 COG4929 COG4929, Uncharacterized membrane-anchored protein Function unknown 56419938 Nonpathogen - hypothetical protein GK1403 5 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 56419977 Common - hypothetical protein GK1442 79 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 56421050 Common comEC late competence protein (DNA uptake) GK2515 179 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 56419193 Common - ABC transporter (ATP-binding protein) GK0658 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 56421685 Common - two-component response regulator (extracellular proteinase response regulator) GK3150 224 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 56419693 Nonpathogen - hypothetical protein GK1158 2 None None None 56421107 Common aspS aspartyl-tRNA synthetase GK2572 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 56418898 Common - phosphomannomutase GK0363 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 56420556 Nonpathogen - hypothetical protein GK2021 3 None None None 56420122 Nonpathogen - hypothetical protein GK1587 1 None None None 56420453 Common - hypothetical protein GK1918 82 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 56420413 Common - oxidoreductase GK1878 173 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 56421083 Common - uridine kinase GK2548 81 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 56420329 Common - hypothetical protein GK1794 8 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 56419568 Common - hypothetical protein GK1033 42 COG2045 COG2045, Phosphosulfolactate phosphohydrolase and related enzymes Coenzyme metabolism / General function prediction only 56420459 Common - hypothetical protein GK1924 9 COG0456 RimI, Acetyltransferases General function prediction only 56418632 Common - hypothetical protein GK0097 125 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 56421526 Common - hypothetical protein GK2991 187 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 56420870 Common - hypothetical protein GK2335 93 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 56419686 Common - carbamoyl phosphate synthase small subunit GK1151 235 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 56418854 Common - hypothetical protein GK0319 27 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 56419382 Nonpathogen - hypothetical protein GK0847 3 None None None 56419010 Common ldh L-lactate dehydrogenase GK0475 164 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 56419531 Common ptsI phosphoenolpyruvate-protein phosphotransferase GK0996 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 56420680 Common - hypothetical protein GK2145 2 None None None 56421252 Common rpmI 50S ribosomal protein L35 GK2717 170 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 56419898 Common - hypothetical protein GK1363 20 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 56420119 Common - hypothetical protein GK1584 179 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 56421839 Common - mannose-6-phosphate isomerase (phosphomannose isomerase) ; mannose-1-phosphate guanylyl transferase (GDP-mannose pyrophosphorylase) GK3304 163 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 56419142 Nonpathogen - hypothetical protein GK0607 1 None None None 56421267 Common - two-component response regulator (phosphate regulation) GK2732 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 56420482 Common - transcriptional regulator GK1947 34 COG3711 BglG, Transcriptional antiterminator Transcription 56419185 Common - hypothetical protein GK0650 5 None None None 56421079 Common - hypothetical protein GK2544 2 None None None 56419126 Common - hypothetical protein GK0591 78 COG0701 COG0701, Predicted permeases General function prediction only 56420642 Common - hypothetical protein GK2107 6 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 56420966 Nonpathogen - hypothetical protein GK2431 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 56419783 Nonpathogen - hypothetical protein GK1248 1 None None None 56418843 Common - transposase GK0308 70 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 56419601 Common - hypothetical protein GK1066 134 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 56419805 Common - deacetylase GK1270 125 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 56420282 Common - PTS system, trehalose-specific enzyme II, BC component GK1747 42 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 56419572 Common - divalent cation transport protein GK1037 166 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 56421368 Common - 16S pseudouridylate synthase GK2833 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 56421232 Common - ribonuclease HIII GK2697 27 COG1039 RnhC, Ribonuclease HIII DNA replication, recombination, and repair 56422032 Common rnpA ribonuclease P GK3497 108 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 56420766 Common - sporulation specific N-acetylmuramoyl-L-alanine amidase (spore cortex-lytic enzyme) GK2231 61 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 56421445 Nonpathogen - hypothetical protein GK2910 1 None None None 56420335 Common - precorrin-6Y C5,15-methyltransferase [decarboxylating] (precorrin-6 methyltransferase) GK1800 118 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 56419463 Common - sodium:solute symporter GK0928 157 COG4147 DhlC, Predicted symporter General function prediction only 56421759 Common - transcriptional regulator (ArsR family) GK3224 193 COG0640 ArsR, Predicted transcriptional regulators Transcription 56420951 Common - manganese transport transcriptional regulator GK2416 98 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 56420846 Common - D-alanyl-D-alanine carboxypeptidase (penicilin binding protein) GK2311 158 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 56420952 Nonpathogen - hypothetical protein GK2417 1 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 56422014 Common - hypothetical protein GK3479 6 COG4241 COG4241, Predicted membrane protein Function unknown 56419528 Common - hypothetical protein GK0993 11 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 56420530 Common - phenylacetic acid catabolism protein GK1995 46 COG3396 COG3396, Uncharacterized conserved protein Function unknown 56421427 Common - hypothetical protein GK2892 4 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 56420306 Common - hypothetical protein GK1771 53 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 56419729 Common - signal recognition particle GTPase (docking protein) GK1194 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 56421830 Nonpathogen - hypothetical protein GK3295 1 None None None 56419867 Common tkt transketolase GK1332 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 56419373 Common - lipopolysaccharide N-acetylglucosaminyltransferase GK0838 204 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 56418594 Common - serine/threonine protein kinase GK0059 16 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 56421294 Common - acetyl-CoA synthetase (acetate-CoA ligase) GK2759 222 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 56419428 Nonpathogen - hypothetical protein GK0893 1 None None None 56421365 Common - maltose permease GK2830 63 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 56421698 Common - polysaccharide biosynthesis GK3163 38 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 56421664 Common - hypothetical protein GK3129 21 COG2604 COG2604, Uncharacterized protein conserved in bacteria Function unknown 56419255 Nonpathogen - hypothetical protein GK0720 1 None None None 56419049 Nonpathogen - hypothetical protein GK0514 1 None None None 56418810 Common - ATP-dependent DNA helicase GK0275 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 56419028 Common - transcriptional regulator GK0493 51 COG1396 HipB, Predicted transcriptional regulators Transcription 56419642 Common - hypothetical protein GK1107 4 None None None 56421913 Common prfA peptide chain release factor 1 GK3378 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 56421115 Common - single-strand DNA-specific exonuclease GK2580 199 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 56418735 Common - alcohol dehydrogenase GK0200 171 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 56420971 Common - hypothetical protein GK2436 25 COG2345 COG2345, Predicted transcriptional regulator Transcription 56419774 Common flhF flagellar biosynthesis regulator FlhF GK1239 247 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 56421157 Nonpathogen - hypothetical protein GK2622 1 None None None 56421956 Common - uracil-DNA glycosylase GK3421 128 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 56419287 Common - huntingtin interacting protein E-like protein GK0752 107 COG3177 COG3177, Uncharacterized conserved protein Function unknown 56421862 Common - capsular polysaccharide biosynthesis protein GK3327 60 COG3944 COG3944, Capsular polysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 56418795 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase GK0260 212 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 56419741 Common - hypothetical protein GK1206 3 None None None 56419107 Nonpathogen - hypothetical protein GK0572 1 None None None 56418802 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase GK0267 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 56418835 Common - lantibiotic biosynthesis protein GK0300 7 None None None 56420184 Nonpathogen - hypothetical protein GK1649 1 None None None 56420976 Common - gamma-D-glutamyl-L-diamino acid endopeptidase I (endopeptidase I) GK2441 9 COG2866 COG2866, Predicted carboxypeptidase Amino acid transport and metabolism 56420075 Nonpathogen - hypothetical protein GK1540 1 None None None 56420225 Common - two-component response regulator GK1690 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 56421402 Common - hypothetical protein GK2867 3 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 56421667 Nonpathogen - hypothetical protein GK3132 1 None None None 56419555 Common - methyl-accepting chemotaxis protein GK1020 157 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 56418604 Common - dihydropteroate synthase GK0069 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 56418720 Common - transcriptional regulator (NtrC/NifA family) GK0185 168 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 56419212 Nonpathogen - hypothetical protein GK0677 1 None None None 56421379 Nonpathogen - hypothetical protein GK2844 1 None None None 56419437 Common - heavy metal-transporting ATPase GK0902 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 56419841 Common mutS DNA mismatch repair protein GK1306 206 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 56421068 Common - hypothetical protein GK2533 111 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 56419492 Common - divalent heavy-metal cation transporter GK0957 88 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 56421967 Common - glycosyltransferase involved in cell wall biogenesis GK3432 179 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 56420958 Common - glycine dehydrogenase subunit 2 GK2423 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 56418667 Common rpsK 30S ribosomal protein S11 GK0132 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 56420991 Common - hypothetical protein GK2456 5 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 56421881 Common - NADH dehydrogenase subunit M GK3346 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 56421280 Common - hypothetical protein GK2745 8 None None None 56419308 Common mobB molybdopterin-guanine dinucleotide biosynthesis protein GK0773 46 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 56421175 Common - hypothetical protein GK2640 3 None None None 56419700 Common - hypothetical protein GK1165 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 56418869 Nonpathogen - hypothetical protein GK0334 1 None None None 56418541 Common gyrA DNA gyrase subunit A GK0006 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 56419149 Common - 2-dehydropantoate 2-reductase GK0614 104 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 56421585 Nonpathogen - hypothetical protein GK3050 1 None None None 56419030 Common - transcriptional regulator GK0495 5 COG1476 COG1476, Predicted transcriptional regulators Transcription 56418563 Common - hypothetical protein GK0028 106 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 56420716 Common - tRNA CCA-pyrophosphorylase GK2181 214 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 56421226 Nonpathogen - hypothetical protein GK2691 1 None None None 56418882 Common - hypothetical protein GK0347 17 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 56419093 Common - two-component response regulator GK0558 225 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 56419868 Nonpathogen - hypothetical protein GK1333 1 None None None 56420900 Nonpathogen - hypothetical protein GK2365 1 None None None 56421986 Common - hypothetical protein GK3451 192 COG0388 COG0388, Predicted amidohydrolase General function prediction only 56419608 Common - hypothetical protein GK1073 5 COG4896 COG4896, Uncharacterized protein conserved in bacteria Function unknown 56419597 Nonpathogen - hypothetical protein GK1062 1 None None None 56421536 Common - thioredoxin GK3001 6 None None None 56419963 Common - hypothetical protein GK1428 29 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 56420430 Nonpathogen - hypothetical protein GK1895 1 None None None 56418762 Common - hypothetical protein GK0227 126 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 56418900 Nonpathogen - hypothetical protein GK0365 1 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 56420947 Common - hypothetical protein GK2412 3 None None None 56420542 Nonpathogen - hypothetical protein GK2007 1 None None None 56421137 Common - cysteine desulfurase GK2602 237 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 56419235 Common - asparagine synthetase (glutamine-hydrolyzing) GK0700 159 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 56422006 Common - hypothetical protein GK3471 10 COG4853 COG4853, Uncharacterized protein conserved in bacteria Function unknown 56421131 Common - NH(3)-dependent NAD+ synthetase GK2596 224 COG0171 NadE, NAD synthase Coenzyme metabolism 56418722 Common - 1-pyrroline-5-carboxylate dehydrogenase GK0187 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 56420827 Common - hypothetical protein GK2292 3 COG1547 COG1547, Uncharacterized conserved protein Function unknown 161551792 Common rph ribonuclease PH GK2666 186 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 56419292 Common - transcriptional regulator (Crp family, AMP-binding protein) GK0757 175 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 56418699 Common - hypothetical protein GK0164 15 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 56421925 Common - DNA-directed RNA polymerase delta subunit GK3390 14 COG3343 RpoE, DNA-directed RNA polymerase, delta subunit Transcription 56420506 Common - C4-dicarboxylate transport system (C4-dicarboxylate-binding protein) GK1971 112 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 56418751 Common - spore coat protein F GK0216 3 COG5577 COG5577, Spore coat protein Cell envelope biogenesis, outer membrane 56418974 Common - hypothetical protein GK0439 26 COG3044 COG3044, Predicted ATPase of the ABC class General function prediction only 56419316 Common - hypothetical protein GK0781 64 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 56421700 Common - UDP-N-acetyl-D-mannosaminuronate dehydrogenase GK3165 207 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 56421657 Common - hypothetical protein GK3122 177 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 56421716 Common - hypothetical protein GK3181 25 None None None 56420130 Nonpathogen - hypothetical protein GK1595 1 None None None 56420099 Common - hypothetical protein GK1564 79 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 56420619 Common - cytochrome bd-type ubiquinol oxidase subunit I GK2084 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 56421642 Common secA preprotein translocase subunit SecA GK3107 216 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 56420520 Nonpathogen - hypothetical protein GK1985 6 None None None 56419612 Common - hypothetical protein GK1077 7 COG4838 COG4838, Uncharacterized protein conserved in bacteria Function unknown 56421249 Common - hypothetical protein GK2714 10 COG4508 COG4508, Uncharacterized protein conserved in bacteria Function unknown 56421211 Common - hypothetical protein GK2676 5 None None None 56420862 Common - hypothetical protein GK2327 18 COG3369 COG3369, Uncharacterized conserved protein Function unknown 56420022 Common - hypothetical protein GK1487 249 COG4586 COG4586, ABC-type uncharacterized transport system, ATPase component General function prediction only 56420047 Common - hypothetical protein GK1512 12 COG3594 NolL, Fucose 4-O-acetylase and related acetyltransferases Carbohydrate transport and metabolism 56420895 Nonpathogen - hypothetical protein GK2360 1 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 56419393 Nonpathogen - hypothetical protein GK0858 1 None None None 56419370 Common - hypothetical protein GK0835 3 None None None 56421377 Common leuS leucyl-tRNA synthetase GK2842 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 56421478 Nonpathogen - hypothetical protein GK2943 1 None None None 56420102 Common - transporter GK1567 112 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 56420792 Common - hypothetical protein GK2257 131 COG2096 COG2096, Uncharacterized conserved protein Function unknown 56420622 Common - two-component sensor histidine kinase GK2087 158 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 56418896 Common - hypothetical protein GK0361 83 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 56421730 Common - aspartate kinase GK3195 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 56421778 Nonpathogen - hypothetical protein GK3243 1 None None None 56419219 Common - DNA exonuclease GK0684 138 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 56421932 Common - acetyl-CoA acetyltransferase GK3397 171 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 56420799 Common - ferric ion ABC transporter (permease) GK2264 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 56421180 Common hemC porphobilinogen deaminase GK2645 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 56421852 Common - O-antigen transporter GK3317 60 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 56420671 Common - long-chain fatty-acid-CoA ligase GK2136 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 56420349 Common glpQ glycerophosphoryl diester phosphodiesterase GK1814 170 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 56420145 Common - hypothetical protein GK1610 3 None None None 56420149 Common kinB two-component sensor histidine kinase GK1614 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 56420214 Nonpathogen - hypothetical protein GK1679 1 None None None 56420385 Nonpathogen - hypothetical protein GK1850 1 None None None 56418846 Common - lantibiotic ABC transporter (permease) GK0311 5 COG4200 COG4200, Uncharacterized protein conserved in bacteria Function unknown 56421509 Common - lipoyl synthase GK2974 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 56421628 Nonpathogen - hypothetical protein GK3093 1 None None None 56418906 Common - transposase GK0371 70 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 56420691 Common - two-component sensor histidine kinase GK2156 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 56421242 Common pheS phenylalanyl-tRNA synthetase subunit alpha GK2707 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 56421317 Common - long-chain fatty-acid-CoA ligase GK2782 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 56420206 Common - cytochrome c oxidase (b(o/a)3-type) chain I GK1671 149 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 56418979 Common - hypothetical protein GK0444 5 None None None 56419785 Common tsf elongation factor Ts GK1250 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 56419756 Common fliH flagellar assembly protein H GK1221 35 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 56418785 Common fumC fumarate hydratase GK0250 231 COG0114 FumC, Fumarase Energy production and conversion 56420012 Nonpathogen - hypothetical protein GK1477 1 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 56421025 Common - diacylglycerol kinase GK2490 21 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 56421981 Common - PTS system, glucose-specific enzyme II, A component GK3446 59 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 56421193 Common - 2-isopropylmalate synthase GK2658 215 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 56419359 Common - hypothetical protein GK0824 26 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 56419233 Common - hypothetical protein GK0698 190 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 56420980 Nonpathogen - hypothetical protein GK2445 3 None None None 56420242 Common - hypothetical protein GK1707 2 None None None 56421440 Common - type I restriction-modification system specificity determinant GK2905 87 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 56421400 Common - Mn/Zn ABC transporter (Mn/Zn-binding (lipo)protein) (surface adhesin A) GK2865 170 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 56418966 Common - hypothetical protein GK0431 12 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 56419658 Common - small basic protein GK1123 25 COG3856 Sbp, Uncharacterized conserved protein (small basic protein) Function unknown 56421105 Common - transcriptional activator GK2570 3 None None None 56421234 Common - hypothetical protein GK2699 55 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 56421048 Common holA DNA polymerase III subunit delta GK2513 119 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 56421434 Common - ferrichrome ABC transporter (permease) GK2899 192 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 56420304 Common - hypothetical protein GK1769 20 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 56420561 Common pdhB hypothetical protein GK2026 153 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 56420577 Common - ring-oxidation complex protein 2 (phenylacetic acid catabolism) GK2042 43 COG3396 COG3396, Uncharacterized conserved protein Function unknown 56421043 Common - GTP-binding protein LepA GK2508 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 56421404 Common - hypothetical protein GK2869 9 COG4378 COG4378, Uncharacterized protein conserved in bacteria Function unknown 56420724 Common - hypothetical protein GK2189 16 COG4347 COG4347, Predicted membrane protein Function unknown 56419807 Common - hypothetical protein GK1272 15 COG1873 COG1873, Uncharacterized conserved protein Function unknown 56419166 Common - sugar ABC transporter (ATP-binding protein) GK0631 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 56418575 Common - purine operon repressor GK0040 67 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 56418729 Common - ferrichrome ABC transporter (ATP-binding protein) GK0194 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 56419409 Nonpathogen - hypothetical protein GK0874 5 None None None 56419352 Common spxA transcriptional regulator Spx GK0817 49 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 56421958 Common - serine-protein kinase RsbW GK3423 39 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 56418683 Common - polysaccharide deacetylase GK0148 111 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 56418963 Common - DNA-3-methyladenine glycosidase II GK0428 125 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 56418825 Nonpathogen - hypothetical protein GK0290 1 None None None 56420374 Common - fructose-1-phosphate kinase GK1839 111 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 56419343 Common - hypothetical protein GK0808 3 None None None 56419084 Common - N-acetylmuramoyl-L-alanine amidase GK0549 18 COG5632 COG5632, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 56418567 Common - deoxyribonuclease GK0032 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 56421549 Nonpathogen - hypothetical protein GK3014 1 None None None 56418928 Common - hypothetical protein GK0393 77 COG1556 COG1556, Uncharacterized conserved protein Function unknown 56421292 Common argG argininosuccinate synthase GK2757 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 56420046 Common thiE thiamine-phosphate pyrophosphorylase GK1511 203 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 56422030 Common jag SpoIIIJ-associated protein GK3495 70 COG1847 Jag, Predicted RNA-binding protein General function prediction only 56419595 Common - branched-chain alpha-keto acid dehydrogenase subunit E2 GK1060 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 56418935 Common - hypothetical protein GK0400 143 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 56420354 Common - nicotinate phosphoribosyltransferase GK1819 125 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 56419267 Nonpathogen - hypothetical protein GK0732 1 None None None 56421940 Common - spermidine synthase GK3405 119 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 56420474 Nonpathogen - hypothetical protein GK1939 1 None None None 56420193 Common - acetyl-CoA C-acetyltransferase GK1658 186 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 56420549 Common - glycolate oxidase subunit GK2014 202 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 56421773 Common - macrolide-efflux transporter GK3238 107 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 56421815 Common - hypothetical protein GK3280 93 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 56419957 Common - dihydropyrimidine dehydrogenase GK1422 109 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 56419629 Nonpathogen - hypothetical protein GK1094 2 None None None 56419484 Common mtnA methylthioribose-1-phosphate isomerase GK0949 131 COG0182 COG0182, Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 56419994 Common - iron(III) dicitrate ABC transporter (permease) GK1459 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 56418913 Common - carbon monoxide dehydrogenase middle subunit GK0378 51 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 56418838 Common - lantibiotic ABC transporter (ATP-binding protein) GK0303 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 56420053 Common - spore coat protein GK1518 3 COG5577 COG5577, Spore coat protein Cell envelope biogenesis, outer membrane 56421097 Common - hypothetical protein GK2562 145 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 56419581 Nonpathogen - hypothetical protein GK1046 1 None None None 56419989 Common - hypothetical protein GK1454 130 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 56419444 Common - ABC transporter (permease) GK0909 138 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 56419511 Common - 6-pyruvoyl tetrahydrobiopterin synthase GK0976 91 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 56418675 Common rpsI 30S ribosomal protein S9 GK0140 229 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 56421206 Common sdhB succinate dehydrogenase iron-sulfur subunit GK2671 208 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 56421973 Common - phosphate ABC transporter (permease) GK3438 228 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 56419289 Common - hypothetical protein GK0754 27 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 56420569 Common - repressor in the phenylacetic acid catabolism GK2034 35 COG3327 PaaX, Phenylacetic acid-responsive transcriptional repressor Transcription 56419196 Common hemE uroporphyrinogen decarboxylase GK0661 181 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 56420035 Common - hypothetical protein GK1500 111 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 56421746 Common - hypothetical protein GK3211 17 COG5464 COG5464, Uncharacterized conserved protein Function unknown 56420058 Common - histidine protein kinase GK1523 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 56418951 Common - phosphoadenylyl-sulfate reductase (thioredoxin-dependent) GK0416 167 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 56421221 Common - electron transfer flavoprotein alpha subunit GK2686 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 56419138 Common - stage V sporulation protein R GK0603 44 COG2719 SpoVR, Uncharacterized conserved protein Function unknown 56420599 Common - hypothetical protein GK2064 39 COG0730 COG0730, Predicted permeases General function prediction only 56421975 Common - transposase GK3440 14 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 56421515 Common - branched chain amino acid ABC transporter (substrate-binding protein) GK2980 151 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 56421993 Common qoxB cytochrome aa3 quinol oxidase subunit I GK3458 173 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 56421529 Common - hypothetical protein GK2994 182 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 56420812 Common - N-acetylglucosamine-6-phosphate deacetylase GK2277 124 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 56421897 Common - F0F1-type ATP synthaseB chain GK3362 104 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 56420038 Common - hypothetical protein GK1503 31 COG1683 COG1683, Uncharacterized conserved protein Function unknown 56420780 Common - ferredoxin [4Fe-4S] GK2245 6 COG1141 Fer, Ferredoxin Energy production and conversion 56418558 Common - lysine decarboxylase GK0023 86 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 56421720 Nonpathogen - hypothetical protein GK3185 1 None None None 56420702 Common recU Holliday junction-specific endonuclease GK2167 18 COG3331 PrfA, Penicillin-binding protein-related factor A, putative recombinase General function prediction only 56422026 Common - hypothetical protein GK3491 185 COG1475 Spo0J, Predicted transcriptional regulators Transcription 56419832 Common - hypothetical protein GK1297 76 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 56419044 Nonpathogen - hypothetical protein GK0509 1 None None None 56419739 Common rbgA ribosomal biogenesis GTPase GK1204 181 COG1161 COG1161, Predicted GTPases General function prediction only 56419001 Nonpathogen - gamma-type small acid-soluble spore protein GK0466 1 None None None 56421520 Common - hypothetical protein GK2985 87 COG1801 COG1801, Uncharacterized conserved protein Function unknown 56421903 Common upp uracil phosphoribosyltransferase GK3368 166 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 56419421 Common - hypothetical protein GK0886 46 COG2261 COG2261, Predicted membrane protein Function unknown 56422021 Common - hypothetical protein GK3486 158 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 56419853 Common - medium-chain fatty acid-CoA ligase GK1318 222 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 56420469 Common - ABC transporter (ATP-binding protein) GK1934 249 COG4674 COG4674, Uncharacterized ABC-type transport system, ATPase component General function prediction only 56420460 Nonpathogen ureH urease accessory protein GK1925 13 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 56420709 Common - hypothetical protein GK2174 4 None None None 56421546 Common - hypothetical protein GK3011 4 None None None 56421739 Common - fructokinase GK3204 89 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 56420774 Common - spore coat peptide assembly protein GK2239 46 COG3546 COG3546, Mn-containing catalase Inorganic ion transport and metabolism 56421569 Common - 4-hydroxyphenylacetate-3-hydroxylase GK3034 50 COG2368 COG2368, Aromatic ring hydroxylase Secondary metabolites biosynthesis, transport, and catabolism 56420835 Common - diaminopimelate decarboxylase GK2300 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 56420607 Nonpathogen - hypothetical protein GK2072 1 None None None 56419012 Common - bacterioferritin comigratory protein GK0477 231 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 56421162 Common - hypothetical protein GK2627 140 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 56421270 Common - isocitrate dehydrogenase GK2735 222 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 56420445 Common - ABC transporter (substrate-binding protein) GK1910 98 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 56421005 Common - metal (zinc) ABC transporter (permease) GK2470 194 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 56420405 Common - hypothetical protein GK1870 48 COG0824 FcbC, Predicted thioesterase General function prediction only 56421814 Nonpathogen - hypothetical protein GK3279 1 None None None 56419482 Common - ribose ABC transporter (ATP-binding protein) GK0947 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 56420060 Common - cysteine synthase GK1525 225 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 56421847 Common - transposase of ISBst12-like element GK3312 54 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 56421879 Nonpathogen - hypothetical protein GK3344 1 None None None 56420913 Common - branched-chain alpha-keto acid dehydrogenase E1 component alpha chain (2-oxoisovalerate dehydrogenase alpha subunit) GK2378 162 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 56418780 Common - hypothetical protein GK0245 2 None None None 56419854 Common - 3-hydroxybutyryl-CoA dehydrogenase GK1319 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 56421216 Nonpathogen - hypothetical protein GK2681 3 COG0392 COG0392, Predicted integral membrane protein Function unknown 56421302 Common - hypothetical protein GK2767 98 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 56419064 Common - phage-related head portal protein GK0529 51 COG4695 COG4695, Phage-related protein Function unknown 56420648 Common - hypothetical protein GK2113 19 COG4813 ThuA, Trehalose utilization protein Carbohydrate transport and metabolism 56420787 Common - transposase GK2252 70 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 56420069 Common - malate dehydrogenase (malic enzyme) GK1534 194 COG0281 SfcA, Malic enzyme Energy production and conversion 56419180 Common - ABC transporter (permease) (Na+ exclusion) GK0645 46 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 56419406 Common - hypothetical protein GK0871 152 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 56420166 Common - ABC transporter (ATP-binding protein) GK1631 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 56420087 Common - hypothetical protein GK1552 27 COG1755 COG1755, Uncharacterized protein conserved in bacteria Function unknown 56421806 Common - hypothetical protein GK3271 3 None None None 56419226 Common - spore germination protein GK0691 2 None None None 56421939 Common - agmatinase GK3404 160 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 56419798 Common infB translation initiation factor IF-2 GK1263 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 56419412 Common - transposase of IS654-like element GK0877 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 56420332 Common - cobalamin biosynthesis protein GK1797 97 COG2073 CbiG, Cobalamin biosynthesis protein CbiG Coenzyme metabolism 56420989 Common - phosphate ABC transporter (ATP-binding protein) GK2454 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 56421341 Common - acetyl-CoA synthetase GK2806 222 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 56419065 Common - serine protease (phage related-protein, ClpP family) GK0530 209 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 56421279 Common - DNA-directed DNA polymerase III alpha subunit GK2744 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 56419911 Common - hypothetical protein GK1376 86 COG3384 COG3384, Uncharacterized conserved protein Function unknown 56420992 Common - manganese superoxide dismutase GK2457 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 56420072 Common - ATP-dependent RNA helicase GK1537 224 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 56420737 Common trpC indole-3-glycerol-phosphate synthase GK2202 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 56421491 Common - hypothetical protein GK2956 165 COG0316 IscA, Uncharacterized conserved protein Function unknown 56419275 Common - homoserine/homoserine lactone efflux transporter (RhtB family) GK0740 107 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 56421535 Nonpathogen - hypothetical protein GK3000 2 None None None 56419662 Common sigE sporulation sigma factor SigE GK1127 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 56421553 Common - biotin biosynthesis protein GK3018 116 COG1268 BioY, Uncharacterized conserved protein General function prediction only 56421572 Common - hypothetical protein GK3037 2 None None None 56418622 Common - tRNA/rRNA methyltransferase GK0087 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 56421648 Common fliS flagellar protein FliS GK3113 85 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 56421124 Nonpathogen - hypothetical protein GK2589 1 None None None 56418646 Common rplV 50S ribosomal protein L22 GK0111 235 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 56421601 Common - hypothetical protein GK3066 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 56421791 Common - hypothetical protein GK3256 7 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 56419714 Common - thiamin pyrophosphokinase GK1179 46 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 56418701 Common - transposase of IS653-like element GK0167 20 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 56419950 Common - hypothetical protein GK1415 62 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 56421140 Common - hypothetical protein GK2605 14 COG4492 PheB, ACT domain-containing protein General function prediction only 56419980 Common - hypothetical protein GK1445 84 COG2968 COG2968, Uncharacterized conserved protein Function unknown 56419791 Common - hypothetical protein GK1256 215 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 56421766 Common - transcriptional repressor of the ribose operon GK3231 132 COG1609 PurR, Transcriptional regulators Transcription 56421949 Common - hypothetical protein GK3414 19 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 56420553 Common - hypothetical protein GK2018 45 COG3711 BglG, Transcriptional antiterminator Transcription 56419204 Common - ABC transporter (substrate-binding protein) GK0669 55 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 56420926 Common - hypothetical protein GK2391 134 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 56421874 Common spoIIQ stage II sporulation protein Q GK3339 166 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 56419158 Common - glycine oxidase GK0623 155 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 56420254 Common - hypothetical protein GK1719 32 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 56421742 Common - ABC transporter (substrate-binding protein) GK3207 90 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 56420315 Nonpathogen - hypothetical protein GK1780 1 None None None 161551800 Common - DNA replication intiation control protein YabA GK0027 17 COG4467 COG4467, Uncharacterized protein conserved in bacteria Function unknown 56421142 Common spo0B stage 0 sporulation protein B (sporulation initiation phosphoprotein) GK2607 2 None None None 56420653 Common - metabolite transporter GK2118 121 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 56421335 Common - hypothetical protein GK2800 84 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 56419641 Common - enoyl-CoA hydratase GK1106 183 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 56419817 Common - transcriptional regulator (GntR family) GK1282 134 COG2188 PhnF, Transcriptional regulators Transcription 56421052 Common comEA late competence protein (DNA binding and uptake) GK2517 50 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 56418944 Common - hypothetical protein GK0409 11 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 56420150 Common - fosmidmycin resistance protein GK1615 84 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 56421355 Common - hypothetical protein GK2820 87 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 56421417 Common - hypothetical protein GK2882 118 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 56421793 Common - hypothetical protein GK3258 2 None None None 56420004 Common - hypothetical protein GK1469 152 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 56420644 Nonpathogen - hypothetical protein GK2109 1 None None None 56420491 Common - 2-dehydro-3-deoxyphosphogluconate aldolase GK1956 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 56419975 Common - malic enzyme GK1440 202 COG0281 SfcA, Malic enzyme Energy production and conversion 56419540 Nonpathogen - hypothetical protein GK1005 2 None None None 56419109 Common - stage V sporulation protein R (involved in spore cortex synthesis) GK0574 71 COG2719 SpoVR, Uncharacterized conserved protein Function unknown 56419885 Common - hypothetical protein GK1350 85 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 56419228 Common - AMP-binding enzyme GK0693 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 56421669 Common - flagellar assembly protein FliW GK3134 40 COG1699 COG1699, Uncharacterized protein conserved in bacteria Function unknown 56419948 Nonpathogen - hypothetical protein GK1413 2 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 56420120 Common - hypothetical protein GK1585 96 COG2962 RarD, Predicted permeases General function prediction only 56419513 Common - 7-cyano-7-deazaguanine reductase GK0978 145 COG0780 COG0780, Enzyme related to GTP cyclohydrolase I General function prediction only 56419454 Common - hypothetical protein GK0919 98 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 56420443 Common araH L-arabinose ABC transporter (permease) GK1908 108 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 56421918 Common glpX fructose 1,6-bisphosphatase II GK3383 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 56420232 Common - hypothetical protein GK1697 33 COG3428 COG3428, Predicted membrane protein Function unknown 56421783 Common - potassium-transporting ATPase subunit A GK3248 96 COG2060 KdpA, K+-transporting ATPase, A chain Inorganic ion transport and metabolism 56421840 Nonpathogen - hypothetical protein GK3305 1 None None None 56421081 Common - hypothetical protein GK2546 204 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 56419082 Common - hypothetical protein GK0547 2 None None None 56421705 Common - preprotein translocase subunit SecA GK3170 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 56418601 Common - para-aminobenzoate synthase component I GK0066 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 56420013 Common - hypothetical protein GK1478 121 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 56420909 Common - two-component response regulator GK2374 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 56418790 Common - hypothetical protein GK0255 136 COG2252 COG2252, Permeases General function prediction only 56418614 Common - DNA repair protein RadA GK0079 214 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 56420514 Common glnP glutamine ABC transporter (permease) GK1979 179 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 56419314 Nonpathogen - hypothetical protein GK0779 6 None None None 56420968 Common comGC DNA transport machinery (exogenous DNA-binding protein) GK2433 6 COG4537 ComGC, Competence protein ComGC Intracellular trafficking and secretion 56420954 Common - ribonucleotide-diphosphate reductase subunit alpha GK2419 221 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 56421675 Common - hypothetical protein GK3140 9 None None None 56419931 Common - malate:quinone oxidoreductase GK1396 58 COG0579 COG0579, Predicted dehydrogenase General function prediction only 56421034 Common - deoxyribose-phosphate aldolase GK2499 138 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 56420020 Common - acetyl-CoA synthetase GK1485 210 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 56421269 Common - malate dehydrogenase GK2734 182 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 56418760 Common - carboxylesterase precursor GK0225 47 COG1647 COG1647, Esterase/lipase General function prediction only 56420574 Common - enoyl-CoA hydratase subunit I (phenylacetic acid catabolism) GK2039 181 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 56418886 Common - cadmium efflux system accessory protein (cadmium-binding protein) GK0351 132 COG0640 ArsR, Predicted transcriptional regulators Transcription 56420725 Common qcrC menaquinol-cytochrome c reductase cytochrome b/c subunit GK2190 6 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 56419280 Common - hypothetical protein GK0745 56 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 56419051 Nonpathogen - hypothetical protein GK0516 1 None None None 56420933 Common - hypothetical protein GK2398 35 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 56421135 Common - nicotinate-nucleotide pyrophosphorylase GK2600 204 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 56419461 Common - N-acylamino acid racemase GK0926 144 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 56420825 Common - hypothetical protein GK2290 156 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 56419187 Common - transcriptional regulator GK0652 4 COG1846 MarR, Transcriptional regulators Transcription 56420820 Common - spore maturation protein GK2285 39 COG2715 SpmA, Uncharacterized membrane protein, required for spore maturation in B.subtilis. General function prediction only 56421983 Common - stage V sporulation protein N (L-alanine dehydrogenase GK3448 166 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 56421506 Common - hypothetical protein GK2971 3 None None None 56419303 Common fnr transcriptional regulator of anaerobic genes (FNR/CRP family) GK0768 160 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 56420658 Common - ABC transporter (substrate-binding protein) GK2123 114 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 56418819 Common - O-acetylhomoserine aminocarboxypropyltransferase GK0284 207 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 56419821 Common - sugar ABC transporter (permease) GK1286 110 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 56418676 Common - hypothetical protein GK0141 2 None None None 56421865 Nonpathogen - hypothetical protein GK3330 3 None None None 56419549 Nonpathogen - hypothetical protein GK1014 1 None None None 56422012 Common rplI 50S ribosomal protein L9 GK3477 215 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 56420269 Common - denitrification regulatory protein GK1734 149 COG0714 COG0714, MoxR-like ATPases General function prediction only 56420962 Common - hypothetical protein GK2427 3 None None None 56420673 Common - 4-hydroxyphenylacetate-3-hydroxylase GK2138 50 COG2368 COG2368, Aromatic ring hydroxylase Secondary metabolites biosynthesis, transport, and catabolism 56418787 Common - hypothetical protein GK0252 39 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 56420003 Common - hypothetical protein GK1468 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 56421995 Common - rRNA methylase GK3460 197 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 56419892 Nonpathogen - hypothetical protein GK1357 1 None None None 56420949 Common - hypothetical protein GK2414 3 None None None 56421749 Common - beta-glucosidase (Gentiobiase) (Cellobiase) GK3214 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 56419871 Common - ABC transporter (ATP-binding protein) GK1336 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 56419342 Nonpathogen - hypothetical protein GK0807 1 None None None 56421223 Common - enoyl-CoA hydratase GK2688 180 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 56421729 Common - hypothetical protein GK3194 3 None None None 56419047 Common - bacteriophage-related protein GK0512 18 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 56419131 Nonpathogen - hypothetical protein GK0596 1 None None None 56418715 Common - hypothetical protein GK0180 9 None None None 56421036 Common - hypothetical protein GK2501 165 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 56419325 Common - N-acetyl-gamma-glutamyl-phosphate reductase GK0790 216 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 56421587 Nonpathogen - hypothetical protein GK3052 1 None None None 56421386 Common - hypothetical protein GK2851 45 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 56419151 Common - metal-dependent hydrolase GK0616 11 COG2318 DinB, Uncharacterized protein conserved in bacteria Function unknown 56420169 Nonpathogen - hypothetical protein GK1634 3 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 56420140 Common - transcriptional regulator (MarR family) GK1605 135 COG1846 MarR, Transcriptional regulators Transcription 56419670 Common divIVA cell-division initiation protein (septum placement) GK1135 44 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 56420940 Common spoIIIAD stage III sporulation protein AD GK2405 15 None None None 56419200 Common - hypothetical protein GK0665 29 COG1511 COG1511, Predicted membrane protein Function unknown 56420220 Common - enoyl-CoA hydratase GK1685 178 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 56419602 Common - hypothetical protein GK1067 3 None None None 56418777 Common - redox-sensing transcriptional repressor Rex GK0242 56 COG2344 COG2344, AT-rich DNA-binding protein General function prediction only 56419926 Common - acetamidase/formamidase GK1391 32 COG2421 COG2421, Predicted acetamidase/formamidase Energy production and conversion 56419796 Common - hypothetical protein GK1261 49 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 56419754 Common fliF flagellar MS-ring protein GK1219 124 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 56418988 Common - hypothetical protein GK0453 4 None None None 56419127 Common arsM arsenite S-adenosylmethyltransferase GK0592 204 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 56421969 Nonpathogen - hypothetical protein GK3434 1 None None None 56420129 Common - hypothetical protein GK1594 14 COG3393 COG3393, Predicted acetyltransferase General function prediction only 56420758 Common - hypothetical protein GK2223 9 None None None 56420805 Common - acetamidase/formamidase GK2270 64 COG2421 COG2421, Predicted acetamidase/formamidase Energy production and conversion 56419120 Common - cadmium-transporting ATPase GK0585 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 56419253 Nonpathogen - hypothetical protein GK0718 1 None None None 56419648 Common - penicillin-binding protein 2B GK1113 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 56421785 Nonpathogen - hypothetical protein GK3250 1 None None None 56419996 Common - iron(III) dicitrate ABC transporter (ATP-binding protein) GK1461 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 56421391 Common - nitrate/sulfonate/taurine/bicarbonate ABC transporter (ATP binding protein) GK2856 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 56419843 Common - peptidoglycan hydrolase (DL-endopeptidase II family) (cell wall-binding protein) GK1308 164 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 161551794 Common - cobalt transport protein CbiM GK1809 79 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 56421800 Common - hypothetical protein GK3265 103 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 56420423 Common iolC myo-inositol catabolism protein GK1888 182 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 56419553 Common - hypothetical protein GK1018 32 COG0456 RimI, Acetyltransferases General function prediction only 56419802 Common - bifunctional riboflavin kinase/FMN adenylyltransferase GK1267 211 COG0196 RibF, FAD synthase Coenzyme metabolism 56420605 Common - hypothetical protein GK2070 117 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 56421214 Common - dolichyl-phosphate mannose synthase GK2679 192 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 56421991 Common qoxD cytochrome aa3 quinol oxidase subunit IV GK3456 10 COG3125 CyoD, Heme/copper-type cytochrome/quinol oxidase, subunit 4 Energy production and conversion 56421803 Common - hypothetical protein GK3268 13 COG4938 COG4938, Uncharacterized conserved protein Function unknown 56421828 Common - hypothetical protein GK3293 32 COG4249 COG4249, Uncharacterized protein containing caspase domain General function prediction only 56418697 Nonpathogen - hypothetical protein GK0162 6 None None None 56421618 Common - hypothetical protein GK3083 6 COG1950 COG1950, Predicted membrane protein Function unknown 56420741 Common aroB 3-dehydroquinate synthase GK2206 207 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 56420297 Common pepT peptidase T GK1762 62 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 56420322 Common - homoserine O-succinyltransferase GK1787 64 COG1897 MetA, Homoserine trans-succinylase Amino acid transport and metabolism 56420223 Common - DNA topoisomerase III GK1688 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 56420613 Common - hypothetical protein GK2078 7 COG2149 COG2149, Predicted membrane protein Function unknown 56418629 Common rplA 50S ribosomal protein L1 GK0094 244 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 56419332 Nonpathogen - hypothetical protein GK0797 1 None None None 56418749 Common - hypothetical protein GK0214 15 COG1971 COG1971, Predicted membrane protein Function unknown 56418923 Nonpathogen - hypothetical protein GK0388 1 None None None 56418669 Common rplQ 50S ribosomal protein L17 GK0134 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 56421659 Common - hypothetical protein GK3124 37 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 56419558 Common kgd alpha-ketoglutarate decarboxylase GK1023 147 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 56418868 Common - hypothetical protein GK0333 13 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 56419140 Common - cytochrome bd-type ubiquinol oxidase subunit II GK0605 11 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 56419906 Common - hypothetical protein GK1371 54 COG2391 COG2391, Predicted transporter component General function prediction only 56420261 Common - DNA-directed RNA polymerase ECF-type sigma factor GK1726 169 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 56421911 Common spoIIR stage II sporulation protein R (pro-sigma-E processing factor) GK3376 15 None None None 56421061 Common - hypothetical protein GK2526 45 COG2179 COG2179, Predicted hydrolase of the HAD superfamily General function prediction only 56419095 Common - C4-dicarboxylate transport system (substrate-bindindg protein) GK0560 105 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 56421714 Common - hypothetical protein GK3179 27 COG5340 COG5340, Predicted transcriptional regulator Transcription 56419902 Common - urocanate hydratase GK1367 97 COG2987 HutU, Urocanate hydratase Amino acid transport and metabolism 56421438 Nonpathogen - hypothetical protein GK2903 2 None None None 56418724 Common - NAD-specific glutamate dehydrogenase (NAD-GDH) GK0189 180 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 56418884 Common - transposase GK0349 93 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 56421976 Common - transposase GK3441 148 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 56420819 Common - spore maturation protein GK2284 39 COG0700 SpmB, Uncharacterized membrane protein Function unknown 56420391 Common - beta-glucosidase GK1856 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 56420398 Common - hypothetical protein GK1863 94 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 56422004 Common - serine protease Do GK3469 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 56421228 Common - recombination and DNA strand exchange inhibitor protein GK2693 204 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 56418740 Common - two-component response regulator GK0205 219 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 56419198 Common - protoporphyrinogen oxidase GK0663 53 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 56420401 Common - assimilatory nitrate reductase catalytic subunit GK1866 195 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 56420718 Common - hypothetical protein GK2183 49 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 56419036 Nonpathogen - hypothetical protein GK0501 1 None None None 56418586 Common - hypothetical protein GK0051 154 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 56419021 Common - serine protein kinase GK0486 71 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 56421091 Common alaS alanyl-tRNA synthetase GK2556 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 56421771 Common - transposase GK3236 23 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 56421887 Common - NADH dehydrogenase subunit H GK3352 189 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 56419526 Common - PTS system, glucose-specific enzyme II, A component GK0991 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 56420132 Common - CoA dehydrogenase GK1597 165 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 56419334 Common - ATP-dependent Clp protease ATP-binding subunit GK0799 223 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 56420764 Common - hypothetical protein GK2229 4 COG5581 COG5581, Predicted glycosyltransferase Cell envelope biogenesis, outer membrane 56421173 Common valS valyl-tRNA synthetase GK2638 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 56419181 Common - hypothetical protein GK0646 47 COG3481 COG3481, Predicted HD-superfamily hydrolase General function prediction only 56421459 Common pgi glucose-6-phosphate isomerase GK2924 209 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 56420522 Common - transposase GK1987 70 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 56420115 Common - purine-nucleoside phosphorylase GK1580 101 COG0813 DeoD, Purine-nucleoside phosphorylase Nucleotide transport and metabolism 56421752 Common - pyruvate dehydrogenase E1 (lipoamide) alpha subunit GK3217 156 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 56420117 Common - hypothetical protein GK1582 171 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 56419538 Nonpathogen - hypothetical protein GK1003 1 None None None 56418656 Common rplF 50S ribosomal protein L6 GK0121 231 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 56421310 Nonpathogen - hypothetical protein GK2775 1 None None None 56421012 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GK2477 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 56419570 Common - aminotransferase A GK1035 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 56418596 Common - hypoxanthine-guanine phosphoribosyltransferase GK0061 151 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 56419380 Nonpathogen - hypothetical protein GK0845 1 None None None 56420186 Common - pirin-like protein GK1651 148 COG1741 COG1741, Pirin-related protein General function prediction only 56420327 Common - uroporphyrin-III C-methyltransferase GK1792 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 56420998 Common - phosphate ABC transporter (phosphate-binding protein) GK2463 194 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 56421251 Common rplT 50S ribosomal protein L20 GK2716 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 56420803 Common - hypothetical protein GK2268 2 None None None 56419017 Common - hypothetical protein GK0482 138 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 56418577 Common spoVG regulatory protein SpoVG GK0042 24 COG2088 SpoVG, Uncharacterized protein, involved in the regulation of septum location Cell envelope biogenesis, outer membrane 56419089 Common - hypothetical protein GK0554 2 None None None 56420685 Common - galactokinase GK2150 98 COG0153 GalK, Galactokinase Carbohydrate transport and metabolism 56421832 Common - phosphomannomutase GK3297 238 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 56419772 Common flhB flagellar biosynthesis protein FlhB GK1237 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 56419726 Common acpP acyl carrier protein GK1191 210 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 56421696 Common - hypothetical protein GK3161 3 None None None 56420872 Common - beta-glucosidase GK2337 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 56421880 Common - NADH dehydrogenase subunit N GK3345 208 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 56418733 Nonpathogen - hypothetical protein GK0198 1 None None None 56421325 Common - hypothetical protein GK2790 19 COG1714 COG1714, Predicted membrane protein/domain Function unknown 56418717 Common - hypothetical protein GK0182 24 COG3739 COG3739, Uncharacterized integral membrane protein Function unknown 56418747 Common - K+ uptake transporter (Trk family) GK0212 85 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 56421287 Common - alanine dehydrogenase GK2752 166 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 56418800 Common - phosphoribosylaminoimidazole synthetase GK0265 235 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 56421074 Nonpathogen - hypothetical protein GK2539 1 None None None 56419499 Common - hypothetical protein GK0964 81 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 56419695 Nonpathogen - hypothetical protein GK1160 3 None None None 56419236 Common - Na+ driven multidrug efflux pump GK0701 169 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 56418833 Nonpathogen - hypothetical protein GK0298 3 None None None 56420853 Common spoIIM stage II sporulation protein M GK2318 13 COG1300 SpoIIM, Uncharacterized membrane protein Function unknown 56419589 Common - hypothetical protein GK1054 10 COG5503 COG5503, Uncharacterized conserved small protein Function unknown 56419743 Common sucC succinyl-CoA synthetase subunit beta GK1208 207 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 56419008 Common - hypothetical protein GK0473 25 COG4587 COG4587, ABC-type uncharacterized transport system, permease component General function prediction only 56420274 Nonpathogen - sperm protamine P1 GK1739 1 None None None 56420916 Common - leucine dehydrogenase GK2381 144 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 56419856 Common - hypothetical protein GK1321 37 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 56420032 Common - hypothetical protein GK1497 222 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 56419827 Common - hypothetical protein GK1292 87 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 56419562 Common - 3-hydroxyisobutyrate dehydrogenase GK1027 195 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 56420428 Common - sugar ABC transporter (permease) GK1893 110 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 56421570 Common - transcriptional regulator (LysR family) GK3035 190 COG0583 LysR, Transcriptional regulator Transcription 56421393 Common - hypothetical protein GK2858 5 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 56420368 Common - methionyl aminopeptidase GK1833 249 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 56419170 Common - hypothetical protein GK0635 6 None None None 56421834 Common - O-antigen transporter GK3299 60 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 56419446 Common - ribonucleotide-diphosphate reductase subunit alpha GK0911 219 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 56419787 Common - ribosome recycling factor GK1252 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 56419410 Nonpathogen - hypothetical protein GK0875 3 None None None 56420302 Common - hypothetical protein GK1767 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 56421406 Nonpathogen - hypothetical protein GK2871 1 None None None 56419353 Common - hypothetical protein GK0818 53 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 56421382 Common - hypothetical protein GK2847 7 None None None 56418641 Common rplC 50S ribosomal protein L3 GK0106 249 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 56420340 Common - precorrin-3B methylase GK1805 185 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 56421312 Common - acetyl-CoA acetyltransferase GK2777 173 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 56418573 Common - small acid-soluble spore protein (minor alpha/beta-type SASP) GK0038 10 None None None 56420876 Common - two-component sensor histidine kinase GK2341 191 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 56420170 Common - hypothetical protein GK1635 66 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 56419345 Nonpathogen - hypothetical protein GK0810 1 None None None 56419147 Common - carbon starvation protein GK0612 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 56420356 Nonpathogen - hypothetical protein GK1821 1 None None None 56420519 Common - pterin-4-alpha-carbinolamine dehydratase (pterin carbinolamine dehydratase) GK1984 104 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 56418937 Common - hypothetical protein GK0402 23 None None None 56418660 Common rplO 50S ribosomal protein L15 GK0125 220 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 56420631 Common - hypothetical protein GK2096 4 None None None 56421845 Common - transposase GK3310 30 None None None 56419920 Common - hypothetical protein GK1385 92 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 56419419 Common - site-specific recombinase (resolvase family) GK0884 100 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 56418911 Common - multidrug-efflux transporter GK0376 98 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 56419042 Nonpathogen - hypothetical protein GK0507 1 None None None 56419707 Common fmt methionyl-tRNA formyltransferase GK1172 218 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 56419587 Common - potassium transport system NAD-binding component GK1052 176 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 56419780 Common cheD protein required for methylation of methyl-accepting chemotaxis protein (MCPs) GK1245 87 COG1871 CheD, Chemotaxis protein; stimulates methylation of MCP proteins Cell motility and secretion / Signal transduction mechanisms 56420462 Common ureG urease accessory protein GK1927 143 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 56419955 Common - beta-alanine synthase GK1420 199 COG0388 COG0388, Predicted amidohydrolase General function prediction only 56421817 Nonpathogen - hypothetical protein GK3282 1 None None None 56420195 Common - branched-chain amino acid ABC transporter (permease) GK1660 154 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 56420376 Common - hypothetical protein GK1841 180 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 56420851 Common - hypothetical protein GK2316 3 None None None 56419282 Common - hypothetical protein GK0747 129 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 56419617 Common ctaC cytochrome c oxidase subunit II GK1082 155 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 56420641 Nonpathogen - hypothetical protein GK2106 2 None None None 56421096 Common - ATP-dependent exonuclease V GK2561 149 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 56419623 Nonpathogen - hypothetical protein GK1088 1 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 56420033 Common - hypothetical protein GK1498 25 None None None 56420534 Nonpathogen - hypothetical protein GK1999 1 None None None 56418942 Common - hypothetical protein GK0407 73 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 56420848 Common - purine nucleoside phosphorylase GK2313 164 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 56418953 Common - hypothetical protein GK0418 5 COG4840 COG4840, Uncharacterized protein conserved in bacteria Function unknown 56419486 Common - hypothetical protein GK0951 206 COG0388 COG0388, Predicted amidohydrolase General function prediction only 56419740 Common - ribonuclease HII GK1205 206 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 56420029 Common - hypothetical protein GK1494 113 COG2135 COG2135, Uncharacterized conserved protein Function unknown 56419620 Common ctaF cytochrome c oxidase subunit IV GK1085 3 COG3125 CyoD, Heme/copper-type cytochrome/quinol oxidase, subunit 4 Energy production and conversion 56421041 Common hrcA heat-inducible transcription repressor GK2506 151 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 56419656 Common - hypothetical protein GK1121 25 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 56419168 Nonpathogen - hypothetical protein GK0633 2 None None None 56420333 Common - precorrin-4 methylase GK1798 201 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 56420555 Common - di-tripeptide ABC transporter (permease) GK2020 84 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 56418823 Common - NADH dehydrogenase (ubiquinone) chain 4 GK0288 2 None None None 56421195 Common ilvH acetolactate synthase 3 regulatory subunit GK2660 193 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 56420313 Common - hypothetical protein GK1778 3 None None None 56419614 Common - pyruvate carboxylase GK1079 240 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 56419633 Common - hypothetical protein GK1098 218 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 56418921 Common - hypothetical protein GK0386 107 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 56421760 Common - hypothetical protein GK3225 2 None None None 56419361 Common - lytic transglycosylase GK0826 180 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 56419965 Common gltC transcription activator of glutamate synthase(LysR family) GK1430 192 COG0583 LysR, Transcriptional regulator Transcription 56419478 Nonpathogen - hypothetical protein GK0943 1 None None None 56419769 Common fliP flagellar biosynthesis protein FliP GK1234 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 56420928 Common - geranyltranstransferase (farnesyl-diphosphate synthase) GK2393 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 56419646 Common mraW S-adenosyl-methyltransferase MraW GK1111 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 56420617 Common - hypothetical protein GK2082 46 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 56420177 Common - hypothetical protein GK1642 25 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 56421988 Common - amino acid ABC transporter (substrate-binding protein) GK3453 187 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 56420864 Common - oxidoreductase (short chain dehydrogenase/reductase family) GK2329 238 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 56420679 Nonpathogen - hypothetical protein GK2144 1 None None None 56421641 Common - peptide chain release factor 2 in translation GK3106 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 56420692 Common - two-component response regulator GK2157 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 56421322 Common - thiol peroxidase (superoxide-inducible protein 8) GK2787 122 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 56420371 Common - hypothetical protein GK1836 7 COG3689 COG3689, Predicted membrane protein Function unknown 56421732 Nonpathogen - hypothetical protein GK3197 1 None None None 56420628 Nonpathogen - hypothetical protein GK2093 1 None None None 56419278 Common - hypothetical protein GK0743 2 None None None 56421476 Nonpathogen - hypothetical protein GK2941 1 None None None 56421460 Common - NADH-dependent butanol dehydrogenase GK2925 169 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 56421498 Common - threonine synthase GK2963 218 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 56418909 Common - aldehyde dehydrogenase GK0374 223 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 56418904 Common - methyl-accepting chemotaxis protein GK0369 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 56421244 Common - rRNA methylase GK2709 214 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 56421850 Common - glycosyltransferase GK3315 100 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 56418949 Common - adenylylsulfate kinase GK0414 144 COG0529 CysC, Adenylylsulfate kinase and related kinases Inorganic ion transport and metabolism 56421149 Common minC septum formation inhibitor GK2614 76 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 56421496 Common - nitrogen fixation protein (NifU protein) GK2961 102 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 56420343 Common - cobalt transport protein CbiN GK1808 40 COG1930 CbiN, ABC-type cobalt transport system, periplasmic component Inorganic ion transport and metabolism 56420407 Common - oxidoreductase GK1872 128 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 56420267 Common - hypothetical protein GK1732 4 COG2404 COG2404, Predicted phosphohydrolase (DHH superfamily) General function prediction only 56420421 Common fbaA fructose-1,6-bisphosphate aldolase GK1886 177 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 56419593 Common - dehydrogenase E1 component, alpha subunit (lipoamide) GK1058 154 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 56421533 Common - ABC transporter (permease) GK2998 117 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 56420403 Common - assimilatory nitrite reductase subunit GK1868 217 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 56421634 Common - hypothetical protein GK3099 196 COG3883 COG3883, Uncharacterized protein conserved in bacteria Function unknown 56420789 Common sigX RNA polymerase sigma factor SigX GK2254 167 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 56418947 Common - hypothetical protein GK0412 78 COG2138 COG2138, Uncharacterized conserved protein Function unknown 56419661 Common spoIIGA protease (sporulation sigma-E factor processing peptidase) GK1126 15 None None None 56419865 Common - resolvase GK1330 58 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 56419214 Common - hypothetical protein GK0679 36 COG0398 COG0398, Uncharacterized conserved protein Function unknown 56419789 Common - CDP-diglyceride synthase(phosphatidate cytidylyltransferase) GK1254 207 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 56419336 Nonpathogen - hypothetical protein GK0801 1 None None None 56419241 Common - maltose/maltodextrin transport system (permease) GK0706 156 COG3833 MalG, ABC-type maltose transport systems, permease component Carbohydrate transport and metabolism 56420085 Common - hypothetical protein GK1550 35 None None None 56421579 Common - ribonuclease R GK3044 209 COG0557 VacB, Exoribonuclease R Transcription 56418940 Common - transposase GK0405 66 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 56420923 Common spoIVB stage IV sporulation protein B GK2388 18 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 56421291 Common - argininosuccinate lyase GK2756 228 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 56418866 Common - transcriptional regulator GK0331 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 56418591 Common - hypothetical protein GK0056 229 COG1098 VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) Translation, ribosomal structure and biogenesis 56421877 Common - hypothetical protein GK3342 2 None None None 56420735 Common trpB tryptophan synthase subunit beta GK2200 226 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 56420987 Nonpathogen - hypothetical protein GK2452 3 None None None 56420810 Common - transcriptional regulator (GntR family) GK2275 145 COG2188 PhnF, Transcriptional regulators Transcription 56420829 Common ribH riboflavin synthase subunit beta GK2294 230 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 56421920 Common - putative translaldolase GK3385 158 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 56420508 Common - transporter GK1973 74 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 56420558 Nonpathogen - hypothetical protein GK2023 1 None None None 56419073 Nonpathogen - hypothetical protein GK0538 1 None None None 56419386 Common - hypothetical protein GK0851 6 None None None 56418874 Common - hypothetical protein GK0339 2 None None None 56420775 Common - hypothetical protein GK2240 2 None None None 56418648 Common rplP 50S ribosomal protein L16 GK0113 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 56421872 Common - chromate transporter GK3337 113 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 56419815 Common - hypothetical protein GK1280 3 None None None 56420598 Common - hypothetical protein GK2063 45 COG3439 COG3439, Uncharacterized conserved protein Function unknown 56421798 Nonpathogen - hypothetical protein GK3263 1 None None None 56419067 Common - hypothetical protein GK0532 4 None None None 56418753 Common uppP undecaprenyl pyrophosphate phosphatase GK0218 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 56419712 Common - ribosome-associated GTPase GK1177 163 COG1162 COG1162, Predicted GTPases General function prediction only 56419099 Common - hemolysin GK0564 221 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 56420330 Common - cobyric acid synthase GK1795 151 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 56421285 Common - metal-dependent hydrolase GK2750 122 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 56419494 Common - hypothetical protein GK0959 36 COG4869 PduL, Propanediol utilization protein Secondary metabolites biosynthesis, transport, and catabolism 56419273 Common - transcriptional regulator (GntR family) GK0738 176 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 56420798 Common - cobalamin biosynthesis protein GK2263 152 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 56421646 Nonpathogen - hypothetical protein GK3111 1 None None None 56419471 Common - hypothetical protein GK0936 20 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 56421344 Common - acetoin utilization protein GK2809 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 56421603 Common - thioredoxin reductase GK3068 249 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 56420651 Nonpathogen - hypothetical protein GK2116 4 None None None 56420152 Common - spore germination protein GK1617 15 None None None 56420062 Common - hypothetical protein GK1527 20 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 56421550 Nonpathogen - hypothetical protein GK3015 1 None None None 56421540 Common - arsenate reductase GK3005 109 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 56418972 Nonpathogen - hypothetical protein GK0437 2 None None None 56421781 Common - K+-transporting ATPase c chain GK3246 95 COG2156 KdpC, K+-transporting ATPase, c chain Inorganic ion transport and metabolism 56421056 Common - hypothetical protein GK2521 43 COG1713 COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism Coenzyme metabolism 56420319 Common - hypothetical protein GK1784 46 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 56421073 Nonpathogen - hypothetical protein GK2538 1 None None None 56421859 Common - membrane-bound transcriptional regulator LytR GK3324 65 COG1316 LytR, Transcriptional regulator Transcription 56421564 Common - 5-carboxymethyl-2-hydroxymuconate isomerase GK3029 32 COG3232 HpaF, 5-carboxymethyl-2-hydroxymuconate isomerase Amino acid transport and metabolism 56419431 Common - hypothetical protein GK0896 9 None None None 56420528 Nonpathogen - phenylacetic acid catabolism protein GK1993 5 COG3396 COG3396, Uncharacterized conserved protein Function unknown 56419118 Common - hypothetical protein GK0583 84 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 56421208 Common sdhC succinate dehydrogenase (cytochrome b558 subunit) GK2673 19 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 56420281 Common treA alpha,alpha-phosphotrehalase GK1746 168 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 56419655 Common divIB cell-division initiation protein (septum formation) GK1120 30 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 56419175 Common - hypothetical protein GK0640 12 COG3679 COG3679, Uncharacterized conserved protein Function unknown 56421353 Common - hypothetical protein GK2818 6 COG4848 COG4848, Uncharacterized protein conserved in bacteria Function unknown 56421169 Nonpathogen - hypothetical protein GK2634 1 COG4966 PilW, Tfp pilus assembly protein PilW Cell motility and secretion / Intracellular trafficking and secretion 56421046 Common - germination protease GK2511 15 None None None 56418708 Common - hypothetical protein GK0173 3 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 56421375 Nonpathogen - hypothetical protein GK2840 1 None None None 56419732 Common rpsP 30S ribosomal protein S16 GK1197 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 56419508 Common - spore germination protein GK0973 10 None None None 56421421 Common - hypothetical protein GK2886 30 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 56421333 Common - septation ring formation regulator EzrA GK2798 20 COG4477 EzrA, Negative regulator of septation ring formation Cell division and chromosome partitioning 56421890 Common - NADH dehydrogenase subunit B GK3355 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 56420493 Common - hypothetical protein GK1958 73 COG2721 UxaA, Altronate dehydratase Carbohydrate transport and metabolism 56421826 Common - hypothetical protein GK3291 7 None None None 56419290 Nonpathogen - hypothetical protein GK0755 12 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 56419838 Common - hypothetical protein GK1303 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 56421599 Common - hypothetical protein GK3064 54 COG1481 COG1481, Uncharacterized protein conserved in bacteria Function unknown 56418539 Common recF recombination protein F GK0004 167 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 56421947 Common - hypothetical protein GK3412 3 COG4844 COG4844, Uncharacterized protein conserved in bacteria Function unknown 56419987 Common - ammonium transporter GK1452 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 56419830 Common - hypothetical protein GK1295 218 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 56421905 Common - hypothetical protein GK3370 16 COG4475 COG4475, Uncharacterized protein conserved in bacteria Function unknown 56420478 Nonpathogen - hypothetical protein GK1943 1 None None None 56422024 Common spo0J stage 0 sporulation protein J (antagonist of Soj) GK3489 188 COG1475 Spo0J, Predicted transcriptional regulators Transcription 56420415 Common - D-xylose ABC transporter (ATP binding protein) GK1880 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 56421927 Common - transcriptional regulator (TetR/AcrR family) GK3392 56 COG1309 AcrR, Transcriptional regulator Transcription 56420910 Common - hypothetical protein GK2375 20 COG3391 COG3391, Uncharacterized conserved protein Function unknown 56421522 Nonpathogen - hypothetical protein GK2987 1 None None None 56418634 Common rpoC DNA-directed RNA polymerase subunit beta' GK0099 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 56420473 Common - methyl-accepting chemotaxis protein GK1938 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 56419246 Common - thiamine pyrophosphate-dependent dehydrogenase, E1 component beta subunit GK0711 218 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 56420288 Nonpathogen - hypothetical protein GK1753 1 None None None 56420545 Common - ABC transporter (ATP-binding protein) GK2010 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 56419999 Nonpathogen - hypothetical protein GK1464 1 None None None 56421007 Common - hypothetical protein GK2472 54 COG1284 COG1284, Uncharacterized conserved protein Function unknown 56421239 Common - molybdenum ABC transporter (molybdate-binding protein) GK2704 164 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 56421707 Common - carboxyl-terminal processing protease GK3172 184 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 56421722 Nonpathogen - hypothetical protein GK3187 1 None None None 56419379 Common - hypothetical protein GK0844 4 None None None 56419269 Common - hypothetical protein GK0734 8 None None None 56420015 Common - transcriptional regulator GK1480 223 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 56420204 Common - cytochrome aa3 controlling protein GK1669 42 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 56419261 Common - spermidine/putrescine ABC transporter (substrate-binding protein) GK0726 135 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 56418548 Common serS seryl-tRNA synthetase GK0013 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 56418620 Common cysS cysteinyl-tRNA synthetase GK0085 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 56419468 Common - hypothetical protein GK0933 12 None None None 56421126 Common ruvB Holliday junction DNA helicase B GK2591 226 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 56421103 Common - transcriptional regulator (TetR/AcrR family) GK2568 155 COG1309 AcrR, Transcriptional regulator Transcription 56420383 Common - ferrous iron uptake system protein B GK1848 165 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 56419299 Nonpathogen - hypothetical protein GK0764 1 None None None 56419364 Common - hypothetical protein GK0829 77 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 56420244 Common - hypothetical protein GK1709 39 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 56421319 Nonpathogen - hypothetical protein GK2784 4 None None None 56418782 Nonpathogen - hypothetical protein GK0247 1 None None None 56421186 Common - ATP-dependent protease GK2651 242 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 56419404 Common - hypothetical protein GK0869 2 None None None 56420920 Common - glycerophosphodiester phosphodiesterase GK2385 182 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 56421113 Common - GTP pyrophosphokinase (ppGpp synthetase) GK2578 208 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 56421930 Common - 3-hydroxybutyryl-CoA dehydrogenase GK3395 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 56421590 Common - phosphoglyceromutase GK3055 127 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 56419504 Common - hypothetical protein GK0969 3 None None None 56418689 Common - phosphoglucomutase (glycolysis) GK0154 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 56421471 Common - hypothetical protein GK2936 122 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 56419423 Common - transposase GK0888 31 COG5421 COG5421, Transposase DNA replication, recombination, and repair 56418536 Common dnaA chromosomal replication initiation protein GK0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 56420817 Common - thiol-disulfide oxidoreductase GK2282 196 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 56421300 Nonpathogen - hypothetical protein GK2765 1 None None None 56419424 Common - hypothetical protein GK0889 3 None None None 56420917 Common - phosphate butyryltransferase GK2382 141 COG0280 Pta, Phosphotransacetylase Energy production and conversion 56420229 Common - amino acid permease GK1694 167 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 56420138 Common - propionyl-CoA carboxylase GK1603 154 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 56420113 Nonpathogen - hypothetical protein GK1578 1 None None None 56421102 Common - recombination factor protein RarA GK2567 238 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 56422010 Common - adenylosuccinate synthetase GK3475 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 56420975 Common - hypothetical protein GK2440 2 None None None 56420815 Common - cytochrome c biogenesis protein GK2280 88 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 56421127 Common ruvA Holliday junction DNA helicase motor protein GK2592 209 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 56421486 Common - hypothetical protein GK2951 2 None None None 56418806 Common - adenine deaminase GK0271 69 COG1001 AdeC, Adenine deaminase Nucleotide transport and metabolism 56419183 Common - hypothetical protein GK0648 3 None None None 56420420 Common - hypothetical protein GK1885 87 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 56421361 Nonpathogen - hypothetical protein GK2826 1 None None None 56420070 Common - 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase GK1535 171 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 56419377 Common - hypothetical protein GK0842 6 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 56420873 Common - transposase GK2338 32 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 56421997 Common - hypothetical protein GK3462 22 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 56421653 Common - hypothetical protein GK3118 13 COG5421 COG5421, Transposase DNA replication, recombination, and repair 56420079 Common - ATP-dependent helicase GK1544 132 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 56420134 Common - acetyl-CoA carboxylase biotin carboxylase subunit GK1599 235 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 56421290 Common - hypothetical protein GK2755 146 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 56418598 Common - pantothenate kinase GK0063 133 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 56418817 Common gatA aspartyl/glutamyl-tRNA amidotransferase subunit A GK0282 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 56420602 Common - hypothetical protein GK2067 173 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 56421225 Common - long chain acyl-CoA synthetase GK2690 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 56418769 Common - hypothetical protein GK0234 150 COG2183 Tex, Transcriptional accessory protein Transcription 56418832 Nonpathogen - transposase GK0297 1 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 56420808 Common - hypothetical protein GK2273 101 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 56421694 Common - glycosyltransferase GK3159 224 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 56419305 Common narA molybdopterin cofactor biosynthesis protein GK0770 199 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 56420384 Common - ferrous iron uptake system protein A GK1849 16 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 56421170 Nonpathogen - hypothetical protein GK2635 1 None None None 56420437 Common - alpha-D-mannosidase GK1902 53 COG0383 AMS1, Alpha-mannosidase Carbohydrate transport and metabolism 56420409 Common - xylose kinase (xylulokinase) GK1874 185 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 56419335 Nonpathogen - hypothetical protein GK0800 1 None None None 56419259 Common - spermidine/putrescine ABC transporter (permease) GK0724 180 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 56419162 Nonpathogen - hypothetical protein GK0627 1 None None None 56420719 Common mgsA methylglyoxal synthase GK2184 88 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 56420180 Nonpathogen - hypothetical protein GK1645 5 None None None 56420683 Common - galactose-1-phosphate uridylyltransferase GK2148 14 COG4468 GalT, Galactose-1-phosphate uridyltransferase Carbohydrate transport and metabolism 56418992 Nonpathogen - hypothetical protein GK0457 1 None None None 56419319 Common - hypothetical protein GK0784 103 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 56418719 Common - deoxyribonuclease GK0184 232 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 56421835 Common - hypothetical protein GK3300 169 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 56420518 Common - 3-hydroxybutyrate dehydrogenase GK1983 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 56421090 Common - hypothetical protein GK2555 24 COG4472 COG4472, Uncharacterized protein conserved in bacteria Function unknown 56418738 Common - hypothetical protein GK0203 4 COG2318 DinB, Uncharacterized protein conserved in bacteria Function unknown 56419745 Common smf DNA processing protein (Smf family) GK1210 211 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 56419045 Nonpathogen - hypothetical protein GK0510 1 None None None 56418731 Common - sigma-L-dependent transcriptional regulator GK0196 170 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 56421690 Nonpathogen - hypothetical protein GK3155 5 COG3103 COG3103, SH3 domain protein Signal transduction mechanisms 56420996 Common - phosphate ABC transporter (permease) GK2461 226 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 56421093 Nonpathogen - hypothetical protein GK2558 1 None None None 56419973 Common - intracellular proteinase GK1438 135 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 56420777 Common - hypothetical protein GK2242 13 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 56419653 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase GK1118 210 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 56421663 Common - dTDP-glucose 4,6-dehydratase GK3128 236 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 56419300 Common - hypothetical protein GK0765 133 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 56421712 Nonpathogen - hypothetical protein GK3177 1 None None None 56418792 Common - phosphoribosylaminoimidazole carboxylase catalytic subunit GK0257 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 56419414 Nonpathogen - hypothetical protein GK0879 5 None None None 56421448 Common - integrase/recombinase GK2913 225 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 56419752 Common flgC flagellar basal body rod protein FlgC GK1217 126 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 56420712 Common panD aspartate alpha-decarboxylase GK2177 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 56419667 Common - hypothetical protein GK1132 54 COG1799 COG1799, Uncharacterized protein conserved in bacteria Function unknown 56420824 Common - hypothetical protein GK2289 2 None None None 56420961 Common - DNA/RNA helicase (SNF2 family) GK2426 194 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 56422001 Common - hypothetical protein GK3466 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 56420338 Common - precorrin-6x reductase GK1803 72 COG2099 CobK, Precorrin-6x reductase Coenzyme metabolism 56419733 Common - RNA-binding protein GK1198 43 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 56419103 Common - putative disulfide oxidoreductase GK0568 22 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 56421589 Common eno phosphopyruvate hydratase GK3054 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 56421556 Common - hypothetical protein GK3021 127 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 56419019 Common - rRNA methylase GK0484 160 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 56419438 Common - mercuric ion-binding protein GK0903 111 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 56419058 Nonpathogen - hypothetical protein GK0523 1 None None None 56420251 Common - hypothetical protein GK1716 35 COG0456 RimI, Acetyltransferases General function prediction only 56421275 Common pfkA 6-phosphofructokinase GK2740 161 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 56419634 Common coaD phosphopantetheine adenylyltransferase GK1099 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 56420743 Common cheR chemotactic methyltransferase GK2208 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 56418695 Common - transposase GK0160 14 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 56420907 Common - hypothetical protein GK2372 35 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 56419250 Nonpathogen - hypothetical protein GK0715 1 None None None 56418627 Common nusG transcription antitermination protein NusG GK0092 215 COG0250 NusG, Transcription antiterminator Transcription 56420311 Common thyA thymidylate synthase GK1776 138 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 56418555 Common - hypothetical protein GK0020 5 None None None 56419845 Common - multidrug resistance (MDR) efflux pump GK1310 192 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 56421719 Common - hypothetical protein GK3184 4 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 56419201 Common - hypothetical protein GK0666 2 None None None 56419031 Nonpathogen - hypothetical protein GK0496 1 None None None 56420501 Common - aldehyde dehydrogenase GK1966 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 56418999 Common - hypothetical protein GK0464 3 None None None 56418875 Common - epidermal surface antigen GK0340 138 COG2268 COG2268, Uncharacterized protein conserved in bacteria Function unknown 56421259 Common - hypothetical protein GK2724 3 None None None 56418741 Common - hypothetical protein GK0206 14 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 56419312 Common - cell wall-associated protein precursor GK0777 3 None None None 56420730 Common - hypothetical protein GK2195 15 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 161551796 Common citB aconitate hydratase GK1347 222 COG1048 AcnA, Aconitase A Energy production and conversion 56419034 Nonpathogen - hypothetical protein GK0499 1 None None None 56421364 Common - hypothetical protein GK2829 91 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 56418962 Common - nodulation protein GK0427 100 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 56419551 Nonpathogen - hypothetical protein GK1016 6 None None None 56421044 Common - hypothetical protein GK2509 2 None None None 56421503 Common - hypothetical protein GK2968 117 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 56420447 Common - two-component sensor histidine kinase GK1912 114 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 56420693 Nonpathogen - hypothetical protein GK2158 1 None None None 56420187 Common - nitro/flavin reductase GK1652 91 COG0778 NfnB, Nitroreductase Energy production and conversion 56421755 Common - hypothetical protein GK3220 173 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 56421885 Common - NADH dehydrogenase subunit I GK3350 193 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 56421132 Nonpathogen - hypothetical protein GK2597 2 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 56420513 Common glnM glutamine ABC transporter (permease) GK1978 177 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 56420665 Nonpathogen - hypothetical protein GK2130 1 None None None 56421848 Common - glycosyltransferase GK3313 112 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 56421670 Common - hypothetical protein GK3135 8 COG0146 HyuB, N-methylhydantoinase B/acetone carboxylase, alpha subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 56421841 Common - transposase of IS642-like element GK3306 9 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 56421504 Common - hypothetical protein GK2969 13 COG2445 COG2445, Uncharacterized conserved protein Function unknown 56420884 Common - propionyl-CoA carboxylase GK2349 218 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 56421372 Common - hypothetical protein GK2837 2 None None None 56421327 Common ppnK inorganic polyphosphate/ATP-NAD kinase GK2792 180 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 56420838 Common - sporulation protein GK2303 15 None None None 56420571 Common - 3-hydroxybutyryl-CoA dehydrogenase GK2036 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 56420245 Common - catalase GK1710 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 56420263 Nonpathogen - hypothetical protein GK1728 1 None None None 56420904 Common - arginine/ornithine transport system ATPase GK2369 100 COG1703 ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family Amino acid transport and metabolism 56419459 Common - amidohydrolase GK0924 171 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 56419762 Common flgG flagellar basal body rod protein FlgG GK1227 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 56419824 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase GK1289 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 56419894 Common - glycerol uptake facilitator GK1359 134 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 56420610 Common - glutaredoxin GK2075 13 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 56419433 Common - hypothetical protein GK0898 13 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 56419605 Common - GTP-binding elongation factor EF-G GK1070 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 56418631 Common rplL 50S ribosomal protein L7/L12 GK0096 211 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 56418859 Common - drug-efflux transporter GK0324 207 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 56419390 Common - stage V sporulation protein AE GK0855 15 None None None 56419724 Common - acyl-carrier-protein S-malonyltransferase GK1189 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 56419129 Common - single strand DNAspecific exonuclease GK0594 195 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 56421038 Common - chaperone protein (heat shock protein) GK2503 234 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 56421474 Nonpathogen - hypothetical protein GK2939 1 None None None 56421450 Common - hypothetical protein GK2915 108 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 56420688 Common - glycerol-3-phosphate dehydrogenase GK2153 149 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 56420934 Common - acetyl-CoA carboxylase biotin carboxylase subunit GK2399 234 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 56421673 Common - hypothetical protein GK3138 3 None None None 56421031 Common - hypothetical protein GK2496 156 COG1610 COG1610, Uncharacterized conserved protein Function unknown 56420167 Common - hypothetical protein GK1632 80 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 56421916 Common rpmE 50S ribosomal protein L31 GK3381 184 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 56421468 Common - hypothetical protein GK2933 3 None None None 56420888 Common - hypothetical protein GK2353 9 COG4129 COG4129, Predicted membrane protein Function unknown 56418569 Common - hypothetical protein GK0034 21 COG1658 COG1658, Small primase-like proteins (Toprim domain) DNA replication, recombination, and repair 56421437 Common - hypothetical protein GK2902 24 None None None 56420016 Nonpathogen - hypothetical protein GK1481 1 None None None 56418850 Common - hypothetical protein GK0315 90 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 56420676 Common - hypothetical protein GK2141 3 None None None 56421723 Common - cell wall lytic activity GK3188 143 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 56420466 Common ureB urease subunit beta GK1931 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 56419222 Common gerPD spore germination protein GK0687 2 None None None 56419730 Common - hypothetical protein GK1195 28 COG2739 COG2739, Uncharacterized protein conserved in bacteria Function unknown 56419879 Common sspP acid-soluble spore protein P GK1344 2 None None None 56419887 Common - hypothetical protein GK1352 3 None None None 56419371 Common - lipopolysaccharide N-acetylglucosaminyltransferase GK0836 209 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 56419794 Common - hypothetical protein GK1259 183 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 56419133 Nonpathogen - hypothetical protein GK0598 1 None None None 56419934 Common - oxidoreductase GK1399 141 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 56420293 Common - hypothetical protein GK1758 8 None None None 56419285 Common - cation-transporting ATPase GK0750 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 56419397 Common - hypothetical protein GK0862 3 None None None 56420484 Common - hypothetical protein GK1949 15 COG2405 COG2405, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 56420756 Common engA GTP-binding protein EngA GK2221 222 COG1160 COG1160, Predicted GTPases General function prediction only 56419456 Nonpathogen - hypothetical protein GK0921 1 None None None 56420320 Common - glutathione peroxidase GK1785 115 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 56421384 Common - S-adenosylmethionine synthetase GK2849 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 56419788 Common - undecaprenyl pyrophosphate synthetase (UPP synthetase) GK1253 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 56420006 Common - 3-oxoacyl-[acyl-carrier-protein] reductase GK1471 238 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 56419872 Nonpathogen - hypothetical protein GK1337 1 None None None 56418640 Common rpsJ 30S ribosomal protein S10 GK0105 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 56419160 Common thiG thiazole synthase GK0625 172 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 56418925 Common - hypothetical protein GK0390 18 None None None 56419080 Nonpathogen - hypothetical protein GK0545 1 None None None 56421858 Common - capsular polysaccharide biosynthesis protein GK3323 40 COG4464 CapC, Capsular polysaccharide biosynthesis protein Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 56418636 Common rpsL 30S ribosomal protein S12 GK0101 243 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 56418616 Common ispD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GK0081 197 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 56419172 Common - hypothetical protein GK0637 6 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 56421613 Common - acetyltransferase GK3078 185 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 56419053 Nonpathogen - hypothetical protein GK0518 1 None None None 56418894 Common - dehydrogenase GK0359 161 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 56420481 Common - PTS system, mannitol-permease II, A component GK1946 70 COG4668 MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain Carbohydrate transport and metabolism 56420455 Common - hypothetical protein GK1920 106 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 56419548 Common - hypothetical protein GK1013 2 None None None 56420878 Common - ABC transporter (permease) GK2343 17 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 56421306 Common - ribonucleotide-diphosphate reductase subunit beta GK2771 15 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 56420584 Common proA gamma-glutamyl phosphate reductase GK2049 190 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 56419685 Common pyrC dihydroorotase GK1150 218 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 56421394 Common - hypothetical protein GK2859 3 None None None 56421343 Common - acetoin utilization protein GK2808 119 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 56419546 Nonpathogen - hypothetical protein GK1011 1 None None None 56420492 Common - 2-keto-3-deoxy-gluconate kinase GK1957 196 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 56421063 Common - phosphatidylserine decarboxylase GK2528 96 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 56418772 Common - glycoprotein endopeptidase GK0237 197 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 56418829 Nonpathogen - lantibiotic precursor GK0294 1 None None None 56419941 Common - transcriptional regulator (ArsR family) GK1406 170 COG0640 ArsR, Predicted transcriptional regulators Transcription 56420647 Common - hypothetical protein GK2112 146 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 56419276 Common - hypothetical protein GK0741 39 COG3382 COG3382, Uncharacterized conserved protein Function unknown 56422017 Common rpsF 30S ribosomal protein S6 (BS9) GK3482 211 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 56419536 Nonpathogen - hypothetical protein GK1001 1 None None None 56419112 Common - hypothetical protein GK0577 3 None None None 56418710 Common - transposase GK0175 17 COG5421 COG5421, Transposase DNA replication, recombination, and repair 56419122 Common - transcriptional regulator GK0587 187 COG0640 ArsR, Predicted transcriptional regulators Transcription 56419467 Common - putative RNA polymerase sigma factor SigI GK0932 14 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 56419929 Common - hypothetical protein GK1394 16 None None None 56420563 Common - ABC transporter (ATP-binding protein) GK2028 249 COG1101 PhnK, ABC-type uncharacterized transport system, ATPase component General function prediction only 56418537 Common dnaN DNA polymerase III subunit beta GK0002 216 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 56421724 Nonpathogen - hypothetical protein GK3189 1 None None None 56420427 Common iolI myo-inositol catabolism protein GK1892 47 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 56420700 Common - hypothetical protein GK2165 3 None None None 56421945 Common - hypothetical protein GK3410 6 COG3465 COG3465, Uncharacterized conserved protein Function unknown 56420410 Common - xylose isomerase GK1875 68 COG2115 XylA, Xylose isomerase Carbohydrate transport and metabolism 56421326 Common - protease IV (signal peptide peptidase) GK2791 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 56418581 Common spoVC peptidyl-tRNA hydrolase GK0046 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 56419859 Common - GTP-binding protein protease modulator GK1324 218 COG2262 HflX, GTPases General function prediction only 56419915 Common - type I restriction-modification system DNA methylase GK1380 159 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 56419399 Common - hypothetical protein GK0864 21 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 56421606 Common - imidazole glycerol phosphate synthase subunit HisF GK3071 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 56420449 Common - enoyl-CoA hydratase GK1914 189 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 56420470 Common - ABC transporter (permease) GK1935 143 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 56420637 Common - tryptophan synthase subunit beta GK2102 232 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 56418658 Common rpsE 30S ribosomal protein S5 GK0123 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 56419735 Common rimM 16S rRNA-processing protein GK1200 191 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 56419967 Common gltD glutamate synthase subunit beta GK1432 198 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 56419060 Nonpathogen - hypothetical protein GK0525 2 None None None 56418584 Common spoVT stage V sporulation protein T (transcriptional regulator) GK0049 16 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 56419705 Common priA primosome assembly protein PriA GK1170 216 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 56420126 Common - threonine dehydratase GK1591 214 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 56419425 Common - hypothetical protein GK0890 118 COG2855 COG2855, Predicted membrane protein Function unknown 56419403 Nonpathogen - hypothetical protein GK0868 2 None None None 56421309 Common - alcohol dehydrogenase GK2774 214 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 56420089 Nonpathogen - hypothetical protein GK1554 2 None None None 56419896 Common - hypothetical protein GK1361 179 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 56419443 Common - two-component response regulator GK0908 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 56419812 Common dapA dihydrodipicolinate synthase GK1277 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 56421531 Common - hypothetical protein GK2996 40 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 56421866 Common flhP flagellar hook-basal body protein GK3331 125 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 56419465 Common - amino acid transporter GK0930 192 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 56421907 Common - methyl-accepting chemotaxis protein GK3372 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 56418645 Common rpsS 30S ribosomal protein S19 GK0110 242 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 56421621 Common - excinuclease ABC subunit B GK3086 232 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 56418651 Common rplN 50S ribosomal protein L14 GK0116 247 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 56420076 Common - hypothetical protein GK1541 26 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 56419389 Common - stage V sporulation protein AD GK0854 15 None None None 56421009 Common - endonuclease IV GK2474 100 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 56420064 Common - hypothetical protein GK1529 196 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 56421237 Common - hypothetical protein GK2702 185 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 56419113 Common - hypothetical protein GK0578 75 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 56419502 Nonpathogen - hypothetical protein GK0967 1 None None None 56420318 Nonpathogen - hypothetical protein GK1783 2 None None None 56419338 Nonpathogen - hypothetical protein GK0803 1 None None None 56421483 Common - ABC transporter (substrate-binding protein) GK2948 138 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 56419984 Nonpathogen - hypothetical protein GK1449 1 None None None 56418863 Common - hypothetical protein GK0328 56 COG1511 COG1511, Predicted membrane protein Function unknown 56421787 Common - allantoate amidohydrolase GK3252 85 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 56419473 Common - alcohol dehydrogenase GK0938 199 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 56421433 Common - hypothetical protein GK2898 48 None None None 56419496 Common - acylaminoacyl-peptidase GK0961 161 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 56421875 Common spoIID stage II sporulation protein D GK3340 46 COG2385 SpoIID, Sporulation protein and related proteins Cell division and chromosome partitioning 56419271 Common - multidrug ABC transporter (permease) GK0736 24 None None None 56421212 Common - hypothetical protein GK2677 99 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 56419521 Common - two-component sensor histidine kinase GK0986 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 56418609 Common lysS lysyl-tRNA synthetase GK0074 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 56420733 Common hisC histidinol-phosphate aminotransferase GK2198 239 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 56421870 Nonpathogen - intracellular proteinase inhibitor (BsuPI) GK3335 2 None None None 56418989 Nonpathogen - hypothetical protein GK0454 2 None None None 56418727 Common - ferrichrome ABC transporter (permease) GK0192 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 56421473 Nonpathogen - hypothetical protein GK2938 1 None None None 56419850 Common - acyl-CoA synthetase GK1315 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 56418755 Common - chitooligosaccharide deacetylase GK0220 131 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 56419808 Common spoVFA dipicolinate synthase subunit A GK1273 15 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 56421843 Common - mannosyl transferase GK3308 200 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 56421167 Nonpathogen - hypothetical protein GK2632 2 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 56421922 Common spo0F stage 0 sporulation protein F (two-component response regulator, sporulation initiation phosphotransferase F) GK3387 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 56419016 Common - hypothetical protein GK0481 41 COG3382 COG3382, Uncharacterized conserved protein Function unknown 56421380 Common - hypothetical protein GK2845 2 None None None 56420539 Common - poly-gamma-glutamate biosynthesis (capsule formation) GK2004 79 COG2843 PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) Cell envelope biogenesis, outer membrane 56420527 Common - enoyl-CoA hydratase GK1992 181 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 56418982 Common - hypothetical protein GK0447 32 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 56419230 Common - hypothetical protein GK0695 2 None None None 56421054 Common - hypothetical protein GK2519 147 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 56421893 Common - F0F1 ATP synthase subunit beta GK3358 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 56420108 Common - hypothetical protein GK1573 2 None None None 56421769 Nonpathogen - hypothetical protein GK3234 1 None None None 56420258 Nonpathogen - hypothetical protein GK1723 1 None None None 56420985 Common - 50S ribosomal protein L33 GK2450 94 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 56420464 Common ureE urease accessory protein UreE GK1929 51 COG2371 UreE, Urease accessory protein UreE Posttranslational modification, protein turnover, chaperones 56421592 Common pgk phosphoglycerate kinase GK3057 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 56418757 Common - hypothetical protein GK0222 24 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 56419506 Common - hypothetical protein GK0971 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 56420017 Common - hypothetical protein GK1482 151 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 56419718 Common - hypothetical protein GK1183 50 COG1461 COG1461, Predicted kinase related to dihydroxyacetone kinase General function prediction only 56420703 Common - penicillin-binding protein 1A/1B (PBP1) (penicillin-insensitive transglycosylase (peptidoglycan TGase); penicillin-sensitive transpeptidase (DD-transpeptidase)) GK2168 201 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 56418706 Common - hypothetical protein GK0171 20 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 56420298 Common - 5'-nucleotidase GK1763 140 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 56419932 Nonpathogen - hypothetical protein GK1397 1 None None None 56419960 Common - hypothetical protein GK1425 34 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 56421762 Common - ribose ABC transporter (permease) GK3227 122 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 56418978 Common - hypothetical protein GK0443 40 COG3002 COG3002, Uncharacterized protein conserved in bacteria Function unknown 56421413 Common - hypothetical protein GK2878 66 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 56419908 Common - hypothetical protein GK1373 49 COG2313 IndA, Uncharacterized enzyme involved in pigment biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 56419518 Nonpathogen - hypothetical protein GK0983 1 None None None 56420365 Nonpathogen - hypothetical protein GK1830 1 None None None 56419040 Common - hypothetical protein GK0505 2 None None None 56421023 Common - GTP-binding protein GK2488 241 COG1159 Era, GTPase General function prediction only 56419416 Common - hypothetical protein GK0881 64 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 56421929 Common - acyl-CoA dehydrogenase GK3394 166 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 56420706 Common asnC asparaginyl-tRNA synthetase GK2171 249 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 56421339 Nonpathogen - hypothetical protein GK2804 1 None None None 56420082 Common - cytochrome c oxidase (b(o/a)3-type) chain II GK1547 118 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 56420784 Nonpathogen - hypothetical protein GK2249 1 None None None 56418600 Common - cysteine synthase(O-acetyl-L-serine sulfhydrylase) GK0065 224 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 56420272 Common - nitric oxide dioxygenase GK1737 138 COG1017 Hmp, Hemoglobin-like flavoprotein Energy production and conversion 56418662 Common adk adenylate kinase GK0127 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 56421704 Common - teichoic acid linkage unit synthesis (undecaprenylpyrophosphate-N-aetylglucosamine) GK3169 228 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 56421971 Common - phosphate ABC transporter (substrate-binding protein) GK3436 120 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 56421018 Common dnaG DNA primase GK2483 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 56419242 Common - alpha-amylase GK0707 180 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 56419263 Common - hypothetical protein GK0728 224 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 56419392 Common - hypothetical protein GK0857 69 COG2323 COG2323, Predicted membrane protein Function unknown 56420198 Common - branched-chain amino acid ABC transporter (ATP-binding protein) GK1663 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 56421120 Common - hypothetical protein GK2585 4 None None None 56421000 Common - hypothetical protein GK2465 2 None None None 56420158 Nonpathogen - hypothetical protein GK1623 1 None None None 56418736 Common - hypothetical protein GK0201 30 COG2259 COG2259, Predicted membrane protein Function unknown 56420094 Nonpathogen - hypothetical protein GK1559 1 None None None 56419971 Common - hypothetical protein GK1436 70 COG3001 COG3001, Uncharacterized protein conserved in bacteria Function unknown 56418892 Common - RNA methyltransferase GK0357 198 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 56419637 Common - hypothetical protein GK1102 95 COG3480 SdrC, Predicted secreted protein containing a PDZ domain Signal transduction mechanisms 56421297 Common - hypothetical protein GK2762 51 COG0439 AccC, Biotin carboxylase Lipid metabolism 56419207 Common - D-alanine aminotransferase GK0672 190 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 56419310 Common moaD molybdopterin converting factor (subunit 1) GK0775 27 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 56421465 Common - hypothetical protein GK2930 2 None None None 56420154 Common - hypothetical protein GK1619 50 COG2323 COG2323, Predicted membrane protein Function unknown 56421197 Common - branched-chain amino acid aminotransferase GK2662 212 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 56421517 Common - hypothetical protein GK2982 11 COG3377 COG3377, Uncharacterized conserved protein Function unknown 56420093 Common - hypothetical protein GK1558 175 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 56420594 Common - hypothetical protein GK2059 134 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 56420547 Common - transposase GK2012 25 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 56420101 Nonpathogen - hypothetical protein GK1566 1 None None None 56420854 Common - hypothetical protein GK2319 34 COG1379 COG1379, Uncharacterized conserved protein Function unknown 56421954 Common - hypothetical protein GK3419 58 COG2363 COG2363, Uncharacterized small membrane protein Function unknown 56419248 Common - oxidoreductase (short-chain dehydrogenase:reductase family) GK0713 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 56418970 Common - hypothetical protein GK0435 29 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 56421936 Common argS arginyl-tRNA synthetase GK3401 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 56420826 Common scpA segregation and condensation protein A GK2291 145 COG1354 COG1354, Uncharacterized conserved protein Function unknown 56421184 Common - GTPase EngB GK2649 194 COG0218 COG0218, Predicted GTPase General function prediction only 56419216 Common - ATP-dependent deoxyribonuclease subunit B GK0681 29 COG3857 AddB, ATP-dependent nuclease, subunit B DNA replication, recombination, and repair 56421109 Common - NADH-peroxiredoxin reductase GK2574 247 COG3634 AhpF, Alkyl hydroperoxide reductase, large subunit Posttranslational modification, protein turnover, chaperones 56421774 Common - transposase GK3239 17 COG5421 COG5421, Transposase DNA replication, recombination, and repair 56420667 Common - hypothetical protein GK2132 8 COG4377 COG4377, Predicted membrane protein Function unknown 56421230 Common - hypothetical protein GK2695 30 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 56420202 Common - citrulline related protein GK1667 19 COG4708 COG4708, Predicted membrane protein Function unknown 56421350 Common murC UDP-N-acetylmuramate--L-alanine ligase GK2815 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 56420866 Common - pyrroline-5-carboxylate reductase GK2331 214 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 56419928 Nonpathogen - hypothetical protein GK1393 1 None None None 56419990 Common - recombinase of Bh.Int-like element GK1455 97 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 56421313 Common - 3-ketoacyl-[acyl carrier protein] reductase GK2778 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 56419237 Common - transcriptional regulator (AraC/XylS family) GK0702 111 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 56421577 Nonpathogen - hypothetical protein GK3042 1 None None None 56420660 Common - glutaminase GK2125 72 COG2066 GlsA, Glutaminase Amino acid transport and metabolism 56421563 Common - 5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase GK3028 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 56421332 Nonpathogen - hypothetical protein GK2797 1 None None None 56420674 Common - sodium:proline symporter (osmoregulation) GK2139 157 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 56421179 Common - uroporphyrinogen III cosynthase GK2644 98 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 56421160 Common - signal peptidase (late competence protein) GK2625 139 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 56420218 Common - short chain dehydrogenase GK1683 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 56421013 Common - hypothetical protein GK2478 101 COG3323 COG3323, Uncharacterized protein conserved in bacteria Function unknown 56419781 Common sigD RNA polymerase sigma factor SigD GK1246 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 56418661 Common secY preprotein translocase subunit SecY GK0126 233 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 56418918 Common - hypothetical protein GK0383 54 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 56420300 Common - hypothetical protein GK1765 93 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 56419910 Nonpathogen - hypothetical protein GK1375 1 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 56421734 Common - hypothetical protein GK3199 42 COG3564 COG3564, Uncharacterized protein conserved in bacteria Function unknown 56419356 Common - hypothetical protein GK0821 12 COG4469 CoiA, Competence protein General function prediction only 56419075 Common - phage-related protein (tail protein) GK0540 5 None None None 56420925 Common - arginine repressor GK2390 81 COG1438 ArgR, Arginine repressor Transcription 56420341 Common - cobalt ABC transporter (ATP-binding protein) GK1806 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 56418899 Common - hypothetical protein GK0364 126 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 56418678 Common - ATPase involved in chromosome partitioning GK0143 228 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 56421510 Common - hypothetical protein GK2975 18 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 56418841 Common - lantibiotic biosynthesis protein (response regulator) GK0306 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 56419697 Common - hypothetical protein GK1162 36 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 56420442 Common araR arabinose metabolism transcriptional repressor GK1907 147 COG1609 PurR, Transcriptional regulators Transcription 56420604 Common - hypothetical protein GK2069 40 COG2210 COG2210, Uncharacterized conserved protein Function unknown 56420627 Common - hypothetical protein GK2092 9 COG1742 COG1742, Uncharacterized conserved protein Function unknown 56418687 Common - hypothetical protein GK0152 67 COG1624 COG1624, Uncharacterized conserved protein Function unknown 56421396 Common - starvation-induced protein controlled by sigma-B (general stress protein 20U) GK2861 147 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 56420309 Common - hypothetical protein GK1774 4 None None None 56420596 Common - hypothetical protein GK2061 44 COG2510 COG2510, Predicted membrane protein Function unknown 56420172 Common - glutamate-ammonia ligase GK1637 228 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 56418797 Common - phosphoribosylformylglycinamidine synthase subunit I GK0262 231 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 56421147 Common spoIVFA inhibitor of SpoIVFB (stage IV sporulation protein FA) GK2612 105 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 56420054 Nonpathogen - spore coat protein GK1519 1 None None None 56420763 Nonpathogen - hypothetical protein GK2228 2 None None None 56420565 Common - ABC transporter (substrate-binding protein) GK2030 53 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 56421246 Common - hypothetical protein GK2711 35 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 56420377 Common - hypothetical protein GK1842 10 None None None 56419616 Common ctaB protoheme IX farnesyltransferase GK1081 175 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 56420041 Common - phosphotriesterase GK1506 35 COG1735 Php, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 56420357 Common - stage III sporulation protein J GK1822 215 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 56419489 Common mtnX 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase GK0954 19 COG4359 COG4359, Uncharacterized conserved protein Function unknown 56420234 Nonpathogen - hypothetical protein GK1699 4 None None None 56420796 Common - bifunctional cobalamin biosynthesis protein (cobinamide kinase; cobinamide phosphate guanylyltransferase) GK2261 95 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 56420350 Common - DNA topoisomerase III GK1815 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 56422003 Common - hypothetical protein GK3468 2 None None None 56421028 Common - phosphate starvation-induced protein GK2493 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 56419366 Common - hypothetical protein GK0831 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 56419953 Nonpathogen - hypothetical protein GK1418 1 None None None 56420211 Common - nitric oxide synthase GK1676 11 COG4362 COG4362, Nitric oxide synthase, oxygenase domain Inorganic ion transport and metabolism / Amino acid transport and metabolism 56419803 Common rpsO 30S ribosomal protein S15 GK1268 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 56418693 Common - IS1604-like transposase GK0158 89 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 56421950 Common eutD phosphotransacetylase GK3415 166 COG0280 Pta, Phosphotransacetylase Energy production and conversion 56420031 Nonpathogen - hypothetical protein GK1496 1 None None None 56418878 Common - type I restriction modification system M subunit (site-specific DNA-methyltransferase subunit) GK0343 156 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 56419560 Nonpathogen - hypothetical protein GK1025 1 None None None 56420227 Common - hypothetical protein GK1692 6 None None None 56419475 Common - hypothetical protein GK0940 2 None None None 56419836 Common - 2-oxoglutarate synthase(2-oxoglutarate-ferredoxin oxidoreductase) alpha subunit GK1301 111 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 56418572 Common - veg protein GK0037 18 COG4466 Veg, Uncharacterized protein conserved in bacteria Function unknown 56418931 Common - transcriptional regulator (GntR family) GK0396 147 COG2186 FadR, Transcriptional regulators Transcription 56420179 Common - hypothetical protein GK1644 18 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 56421423 Common - hypothetical protein GK2888 7 COG0506 PutA, Proline dehydrogenase Amino acid transport and metabolism 56419491 Common - methionine salvage pathway enzyme E-2/E-2' GK0956 37 COG1791 COG1791, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 56421984 Common - hypothetical protein GK3449 33 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 56420898 Nonpathogen - hypothetical protein GK2363 1 None None None 56421348 Nonpathogen - hypothetical protein GK2813 1 COG4980 GvpP, Gas vesicle protein General function prediction only 56420027 Common - hypothetical protein GK1492 154 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 56419579 Common - short chain dehydrogenase GK1044 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 56420891 Nonpathogen - hypothetical protein GK2356 1 None None None 56421795 Common - hypothetical protein GK3260 3 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 56419585 Common - hippurate hydrolase GK1050 166 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 56421071 Nonpathogen - hypothetical protein GK2536 1 None None None 56421900 Common - F0F1-type ATP synthaseI subunit GK3365 4 None None None 56418938 Nonpathogen - hypothetical protein GK0403 2 None None None 56419689 Common pyrD dihydroorotate dehydrogenase 1B GK1154 239 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 56418671 Common - ABC transporter (ATP-binding protein) GK0136 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 56421202 Common - germination (cortex hydrolysis) and sporulation (stage II, multiple polar septa) GK2667 8 COG5401 COG5401, Spore germination protein General function prediction only 56420633 Common - adenine deaminase GK2098 87 COG1001 AdeC, Adenine deaminase Nucleotide transport and metabolism 56419625 Common - hypothetical protein GK1090 206 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 56421680 Common - hypothetical protein GK3145 13 None None None 56418888 Nonpathogen - hypothetical protein GK0353 1 None None None 56420793 Common - hypothetical protein GK2258 3 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 161551798 Common - O-sialoglycoprotein endopeptidase GK0239 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 56421026 Common - hypothetical protein GK2491 210 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 56418702 Nonpathogen - hypothetical protein GK0166 1 None None None 56421262 Common - hypothetical protein GK2727 208 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 56420822 Nonpathogen - hypothetical protein GK2287 1 None None None 56419909 Nonpathogen - hypothetical protein GK1374 3 COG4026 COG4026, Uncharacterized protein containing TOPRIM domain, potential nuclease General function prediction only 56421824 Common - hypothetical protein GK3289 5 None None None 56419722 Common - fatty acid biosynthesis transcriptional regulator GK1187 17 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 56420745 Common gerCC heptaprenyl diphosphate synthasecomponent II (spore germination protein C3) GK2210 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 56420451 Common - IS1604-like transposase GK1916 82 None None None 56420771 Common - adaptor protein GK2236 13 COG4862 MecA, Negative regulator of genetic competence, sporulation and motility Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Cell motility and secretion 56419169 Nonpathogen - hypothetical protein GK0634 1 None None None 56419179 Common - ABC transporter (ATP-binding protein) (Na+ exclusion) GK0644 249 COG4152 COG4152, ABC-type uncharacterized transport system, ATPase component General function prediction only 56420714 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase GK2179 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 56420194 Common - transcriptional regulator (TetR/AcrR family) GK1659 114 COG1309 AcrR, Transcriptional regulator Transcription 56419297 Common - hypothetical protein GK0762 22 COG4309 COG4309, Uncharacterized conserved protein Function unknown 56419777 Common cheA two-component sensor histidine kinase (chemotaxis protein) GK1242 180 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 56421429 Common - N-methylhydantoinase A GK2894 119 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 56421435 Common - ferrichrome ABC transporter (permease) GK2900 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 56421277 Common - acetyl-CoA carboxylase subunit beta GK2742 219 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 56419191 Common - post-translocation molecular chaperone GK0656 166 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 56418602 Common - para-aminobenzoate/anthranilate synthase glutamine amidotransferase component II GK0067 239 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 56419727 Common rnc ribonuclease III GK1192 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 56419203 Common - acyl-CoA synthetase GK0668 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 56421710 Common - hypothetical protein GK3175 28 COG4632 EpsL, Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Carbohydrate transport and metabolism 56420457 Common dsdA D-serine dehydratase GK1922 52 COG3048 DsdA, D-serine dehydratase Amino acid transport and metabolism 56421240 Common - molybdenum-binding protein GK2705 75 COG1910 COG1910, Periplasmic molybdate-binding protein/domain Inorganic ion transport and metabolism 56419302 Common - nitrite reductase GK0767 100 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 56421118 Common - hypothetical protein GK2583 4 None None None 56421248 Common - hypothetical protein GK2713 88 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 56420056 Nonpathogen - hypothetical protein GK1521 1 None None None 56420417 Common - transposase GK1882 63 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 56419664 Nonpathogen - hypothetical protein GK1129 1 COG1873 COG1873, Uncharacterized conserved protein Function unknown 56418553 Common - hypothetical protein GK0018 63 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 56420710 Nonpathogen - hypothetical protein GK2175 1 None None None 56418927 Nonpathogen - hypothetical protein GK0392 1 None None None 56418743 Common - ABC transporter (ATP-binding protein) GK0208 71 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 56418980 Common - acyl-CoA dehydrogenase GK0445 166 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 56421257 Common dnaB chromosome replication initiation/membrane attachment protein GK2722 14 COG3611 DnaB, Replication initiation/membrane attachment protein DNA replication, recombination, and repair 56419144 Common - hypothetical protein GK0609 2 COG3339 COG3339, Uncharacterized conserved protein Function unknown 56421544 Common - hypothetical protein GK3009 2 None None None 56418540 Common gyrB DNA gyrase subunit B GK0005 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 56419575 Nonpathogen - hypothetical protein GK1040 3 None None None 56419155 Common - hypothetical protein GK0620 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 56420655 Common - hypothetical protein GK2120 117 COG2030 MaoC, Acyl dehydratase Lipid metabolism 56419591 Common - hypothetical protein GK1056 141 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 56420957 Common - transcriptional repressor of the xylose operon GK2422 150 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 56420663 Common - 8-amino-7-oxononanoate synthase GK2128 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 56421501 Common - hypothetical protein GK2966 4 None None None 56421702 Nonpathogen - hypothetical protein GK3167 1 None None None 56420503 Common - transcriptional regulator GK1968 124 COG1414 IclR, Transcriptional regulator Transcription 56421484 Common - hypothetical protein GK2949 23 COG3584 COG3584, Uncharacterized protein conserved in bacteria Function unknown 56419085 Nonpathogen - hypothetical protein GK0550 2 None None None 56420510 Common - K+ channel beta subunit GK1975 205 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 56420836 Common - stage V sporulation protein AF GK2301 15 None None None 56419583 Common - hypothetical protein GK1048 12 COG4109 COG4109, Predicted transcriptional regulator containing CBS domains Transcription 56420136 Common - hydroxymethylglutaryl-CoA lyase GK1601 210 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 56421447 Nonpathogen - hypothetical protein GK2912 6 None None None 56419003 Common - hypothetical protein GK0468 16 COG3557 COG3557, Uncharacterized domain/protein associated with RNAses G and E Translation, ribosomal structure and biogenesis 56420973 Common - hypothetical protein GK2438 93 COG1565 COG1565, Uncharacterized conserved protein Function unknown 56418839 Common - lantibiotic biosynthesis protein GK0304 9 None None None 56420767 Common - hypothetical protein GK2232 22 COG2339 COG2339, Predicted membrane protein Function unknown 56422008 Common - two-component sensor histidine kinase GK3473 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 56419847 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase GK1312 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 56420813 Common - two-component sensor histidine kinase GK2278 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 56419091 Nonpathogen - hypothetical protein GK0556 1 None None None 56420394 Common - PTS system, cellobiose-specific enzyme II, B component GK1859 31 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 56420919 Common - hypothetical protein GK2384 2 None None None 56419317 Common - hypothetical protein GK0782 78 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 56418804 Nonpathogen - hypothetical protein GK0269 1 None None None 56420695 Nonpathogen - hypothetical protein GK2160 1 None None None 56421111 Nonpathogen - hypothetical protein GK2576 1 None None None 56420649 Common - oxidoreductase GK2114 194 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 56420278 Common - hypothetical protein GK1743 58 COG0824 FcbC, Predicted thioesterase General function prediction only 56421692 Common - hypothetical protein GK3157 158 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 56421177 Common - glutamate-1-semialdehyde aminotransferase GK2642 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 56421837 Common - transposase GK3302 18 COG5421 COG5421, Transposase DNA replication, recombination, and repair 56421962 Nonpathogen - hypothetical protein GK3427 1 None None None 56419645 Common - hypothetical protein GK1110 20 COG4365 COG4365, Uncharacterized protein conserved in bacteria Function unknown 56421283 Common - hypothetical protein GK2748 2 None None None 56420435 Common - transposase GK1900 34 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 56421623 Common - hypothetical protein GK3088 10 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 56421139 Common - prephenate dehydratase GK2604 213 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 56421235 Common - transcriptional regulator (MarR family) GK2700 96 COG1846 MarR, Transcriptional regulators Transcription 56419691 Nonpathogen - hypothetical protein GK1156 1 None None None 56420271 Common purU formyltetrahydrofolate deformylase GK1736 217 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 56420182 Common - suppressor of ppGpp-regulated growth inhibitor (ChpA/MazF) GK1647 7 COG2336 MazE, Growth regulator Signal transduction mechanisms 56420200 Common - hypothetical protein GK1665 70 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 56419747 Common xerC site-specific tyrosine recombinase XerC GK1212 231 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 56418994 Common - formate dehydrogenase chain A GK0459 216 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 56419055 Nonpathogen - hypothetical protein GK0520 1 None None None 56419105 Common - phosphomannomutase GK0570 240 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 56421856 Common - hypothetical protein GK3321 25 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 56420111 Nonpathogen - hypothetical protein GK1576 1 None None None 56421315 Common - acyl-CoA dehydrogenase GK2780 146 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 56419943 Common - transcriptional regulator (LysR family) GK1408 193 COG0583 LysR, Transcriptional regulator Transcription 56420486 Common - methylmalonate-semialdehyde dehydrogenase GK1951 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 56420586 Common - hypothetical protein GK2051 11 COG2246 COG2246, Predicted membrane protein Function unknown 56420937 Common spoIIIAG stage III sporulation protein AG GK2402 15 None None None 56420496 Common - dihydrodipicolinate synthase GK1961 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 56420000 Common - hypothetical protein GK1465 16 COG0456 RimI, Acetyltransferases General function prediction only 56418638 Common fus elongation factor G GK0103 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 56421066 Common motB flagellar motor protein MotB GK2531 155 COG1360 MotB, Flagellar motor protein Cell motility and secretion 56421583 Nonpathogen - hypothetical protein GK3048 1 None None None 56421683 Nonpathogen - hypothetical protein GK3148 1 None None None 56422019 Common - hypothetical protein GK3484 187 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 56421329 Common - small acid-soluble spore protein (major alpha-type SASP) GK2794 13 None None None 56421086 Common - caffeoyl-CoA O-methyltransferase GK2551 86 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 56419174 Common - hypothetical protein GK0639 26 COG4399 COG4399, Uncharacterized protein conserved in bacteria Function unknown 56419848 Common hfq RNA-binding protein Hfq GK1313 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 56421089 Common - hypothetical protein GK2554 172 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 56420483 Common - PTS system, mannitol-permease II, BC component GK1948 41 COG2213 MtlA, Phosphotransferase system, mannitol-specific IIBC component Carbohydrate transport and metabolism 56420246 Nonpathogen - hypothetical protein GK1711 1 None None None 56419011 Common - K+ channel subunit GK0476 6 None None None 56418830 Common - transposase of ISBst12-like element GK0295 45 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 56421320 Common - acetate kinase GK2785 162 COG0282 ackA, Acetate kinase Energy production and conversion 56419770 Common fliQ flagellar biosynthesis protein FliQ GK1235 98 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 56420578 Nonpathogen - phenylacetic acid catabolism protein GK2043 3 COG3460 COG3460, Uncharacterized enzyme of phenylacetate metabolism Secondary metabolites biosynthesis, transport, and catabolism 56419759 Common - hypothetical protein GK1224 4 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 56418544 Common - inositol-5-monophosphate dehydrogenase GK0009 242 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 56419544 Common - tRNA (5-methylaminomethyl-2-thiouridylate)- methyltransferase GK1009 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 56420856 Common - hypothetical protein GK2321 205 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 56421757 Common - arsenate reductase (arsenical pump modifier) GK3222 148 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 56418565 Common - transition state regulator GK0030 16 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 56420124 Common - multidrug efflux protein GK1589 146 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 56419229 Common - hypothetical protein GK0694 48 COG2311 COG2311, Predicted membrane protein Function unknown 56419606 Common - hypothetical protein GK1071 2 None None None 56421709 Nonpathogen - hypothetical protein GK3174 1 None None None 56419683 Common pyrP uracil transporter GK1148 125 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 56420026 Common - long-chain fatty-acid-CoA ligase GK1491 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 56419534 Common - cell wall-associated protein precursor GK0999 81 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 56418770 Common - hypothetical protein GK0235 12 COG3091 SprT, Uncharacterized protein conserved in bacteria Function unknown 56420189 Common - acyl-CoA dehydrogenase GK1654 160 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 56421568 Common - 3,4-dihydroxyphenylacetate 2,3-dioxygenase GK3033 40 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 56419673 Nonpathogen - hypothetical protein GK1138 1 None None None 56421345 Common - transcriptional regulator involved in carbon catabolite control GK2810 130 COG1609 PurR, Transcriptional regulators Transcription 56420993 Nonpathogen - hypothetical protein GK2458 1 None None None 56419413 Common - hypothetical protein GK0878 3 None None None 56418618 Common - glutamyl-tRNA synthetase (glutamate--tRNA ligase) GK0083 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 56421943 Common - metal-dependent protease GK3408 81 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 56418827 Nonpathogen - hypothetical protein GK0292 1 None None None 56418690 Common - D-fructose-6-phosphate amidotransferase GK0155 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 56420265 Common - integrase/recombinase GK1730 230 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 56418681 Nonpathogen - hypothetical protein GK0146 1 None None None 56419569 Common - NADPH:quinone oxidoreductase GK1034 216 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 56419764 Common fliL flagellar basal body-associated protein FliL GK1229 23 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 56421687 Common - hypothetical protein GK3152 134 COG1739 COG1739, Uncharacterized conserved protein Function unknown 56418847 Common - lantibiotic ABC transporter (ATP-binding protein) GK0312 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 56420209 Common - hypothetical protein GK1674 70 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 56421644 Common - ribosomal protein S30EA GK3109 174 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 56418857 Nonpathogen - hypothetical protein GK0322 1 None None None 56421370 Common - transporter involved in the export of O-antigen and teichoic acid GK2835 41 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 56419875 Common - two-component response regulator GK1340 225 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 56419321 Common - transposase GK0786 70 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 56420882 Common - tripeptidase GK2347 134 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 56420086 Common bcsA naringenin-chalcone synthase GK1551 39 COG3424 BcsA, Predicted naringenin-chalcone synthase Secondary metabolites biosynthesis, transport, and catabolism 56421999 Common - mannose-6-phosphate isomerase GK3464 51 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 56420945 Common efp elongation factor P GK2410 218 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 56419123 Common - arsenic oxyanion-translocation pump GK0588 142 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 56421869 Common - transcriptional regulator of sigma-E/sigma-K-dependent gene (stage III sporulation protein D) GK3334 15 None None None 56419224 Common gerPB spore germination protein GK0689 2 None None None 56420696 Common csgA sporulation-specific SASP protein (sigma-G-dependent sporulation specific SASP protein) GK2161 2 None None None 56418765 Nonpathogen - hypothetical protein GK0230 1 None None None 56420686 Common - hypothetical protein GK2151 9 COG3579 PepC, Aminopeptidase C Amino acid transport and metabolism 56420902 Common - hypothetical protein GK2367 8 None None None 56419396 Nonpathogen - hypothetical protein GK0861 1 None None None 56421152 Common mreB cell-shape determining protein GK2617 235 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 56420361 Common - hypothetical protein GK1826 35 COG1988 COG1988, Predicted membrane-bound metal-dependent hydrolases General function prediction only 56421864 Common fabZ (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase GK3329 186 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 56421159 Common - hypothetical protein GK2624 24 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 56420516 Common - two-component response regulator GK1981 21 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 56421014 Common - hypothetical protein GK2479 30 COG2384 COG2384, Predicted SAM-dependent methyltransferase General function prediction only 56420295 Common - hypothetical protein GK1760 17 COG3601 COG3601, Predicted membrane protein Function unknown 56420105 Common bioB biotin synthase GK1570 184 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 56420886 Nonpathogen - hypothetical protein GK2351 1 None None None 56418611 Common - hypothetical protein GK0076 18 COG3880 COG3880, Uncharacterized protein with conserved CXXC pairs Function unknown 56420461 Common ureD urease accessory protein GK1926 55 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 56419077 Common - hypothetical protein GK0542 5 None None None 56419135 Common - cassette chromosome recombinase B GK0600 69 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 56421846 Common - teichoic acid biosynthesis GK3311 113 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 56419070 Common - hypothetical protein GK0535 3 None None None 56419881 Common sspO acid-soluble spore protein O GK1346 2 None None None 56421611 Common hisG ATP phosphoribosyltransferase catalytic subunit GK3076 204 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 56421304 Nonpathogen - hypothetical protein GK2769 1 COG1269 NtpI, Archaeal/vacuolar-type H+-ATPase subunit I Energy production and conversion 56421033 Common - Na+:phosphate symporter GK2498 77 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 56421431 Common - sugar transporter GK2896 152 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 56421808 Common - sugar ABC transporter (permease) GK3273 160 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 56419888 Nonpathogen - hypothetical protein GK1353 1 None None None 56419675 Nonpathogen - hypothetical protein GK1140 1 None None None 56418984 Common - hypothetical protein GK0449 2 None None None 56419244 Common - acetoin operon expression regulatory protein GK0709 179 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 56419810 Common - aspartate-semialdehyde dehydrogenase GK1275 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 56421561 Common - branched amino acid ABC transporter (substrate-binding protein) GK3026 136 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 56419014 Common - hypothetical protein GK0479 3 None None None 56420589 Common - hypothetical protein GK2054 8 None None None 56420621 Common - two component response regulator GK2086 210 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 56420600 Common - hypothetical protein GK2065 195 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 56419962 Common - aminotransferase GK1427 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 56421352 Common - hypothetical protein GK2817 205 COG0073 ARC1, EMAP domain General function prediction only 56420525 Common - 4-hydroxybenzoyl-CoA thioesterase GK1990 96 COG0824 FcbC, Predicted thioesterase General function prediction only 56419779 Common cheC chemotactic methyltransferase inhibitor GK1244 30 COG1776 CheC, Chemotaxis protein CheC, inhibitor of MCP methylation Cell motility and secretion / Signal transduction mechanisms 56421260 Common - S-adenosylmethionine decarboxylase proenzyme GK2725 76 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 56421021 Common recO DNA repair protein RecO GK2486 95 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 56421165 Nonpathogen - hypothetical protein GK2630 5 None None None 56421873 Common - gamma-glutamyltranspeptidase GK3338 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 56419066 Common - hypothetical protein GK0531 5 None None None 56419801 Common - tRNA pseudouridine 5S synthase GK1266 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 56419577 Common - hypothetical protein GK1042 3 COG4533 COG4533, ABC-type uncharacterized transport system, periplasmic component General function prediction only 56419687 Common carB carbamoyl phosphate synthase large subunit GK1152 238 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 56420476 Common - gluconokinase GK1941 182 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 56420983 Nonpathogen - hypothetical protein GK2448 15 COG1836 COG1836, Predicted membrane protein Function unknown 56418759 Common murF UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate-D-alanyl-D-alanyl ligase GK0224 211 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 56421679 Common - flagellar biosynthesis GK3144 41 COG2257 COG2257, Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB Function unknown 56421538 Common - hypothetical protein GK3003 2 None None None 56419834 Common spoVS stage V sporulation protein S GK1299 24 COG2359 SpoVS, Uncharacterized protein conserved in bacteria Function unknown 56421145 Common rplU 50S ribosomal protein L21 GK2610 208 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 56418704 Common - transposase of IS5377-like element GK0169 23 COG3385 COG3385, FOG: Transposase and inactivated derivatives DNA replication, recombination, and repair 56421288 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase GK2753 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 56419265 Common - aldehyde dehydrogenase GK0730 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 56420019 Common - ferrous iron uptake system protein A GK1484 47 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 56421337 Common rpsD 30S ribosomal protein S4 GK2802 247 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 56420708 Common - hypothetical protein GK2173 3 COG5353 COG5353, Uncharacterized protein conserved in bacteria Function unknown 56420440 Common araB ribulokinase GK1905 139 COG1069 AraB, Ribulose kinase Energy production and conversion 56420786 Common - transposase GK2251 55 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 56419716 Common rpmB 50S ribosomal protein L28 GK1181 48 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 56420080 Common - thermostable carboxypeptidase GK1545 82 COG2317 COG2317, Zn-dependent carboxypeptidase Amino acid transport and metabolism 56421016 Nonpathogen - hypothetical protein GK2481 1 None None None 56420731 Common - 3-phosphoshikimate 1-carboxyvinyltransferase GK2196 235 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 56421594 Common - transcriptional regulator (central glycolytic gene regulator) GK3059 37 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 56421902 Nonpathogen - hypothetical protein GK3367 1 None None None 56421525 Nonpathogen - hypothetical protein GK2990 1 None None None 56421934 Common - cardiolipin synthetase GK3399 151 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 56421357 Common - hypothetical protein GK2822 79 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 56421116 Common - cation efflux transporter (cadmium/zinc/cobalt) GK2581 215 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 56420760 Common rpsA 30S ribosomal protein S1 GK2225 225 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 56420970 Common comGA DNA transport machinary GK2435 199 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 56420995 Common - hypothetical protein GK2460 4 None None None 56422028 Common gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA GK3493 194 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 56419401 Common - cystathionine gamma-synthase GK0866 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 56421726 Common - single-strand DNA-binding protein GK3191 172 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 56420419 Common - transposase GK1884 148 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 56419532 Common - hypothetical protein GK0997 14 None None None 56419101 Common - hypothetical protein GK0566 2 None None None 56420024 Common - hypothetical protein GK1489 35 COG3694 COG3694, ABC-type uncharacterized transport system, permease component General function prediction only 56420698 Common - hypothetical protein GK2163 2 None None None 56419818 Common - ABC transporter (lipoprotein) GK1283 108 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 56419917 Common - type I restriction-modification system specificity protein GK1382 136 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 56421254 Common thrS threonyl-tRNA synthetase GK2719 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 56419061 Common - hypothetical protein GK0526 28 COG1403 McrA, Restriction endonuclease Defense mechanisms 56420412 Common - aldose 1-epimerase GK1877 90 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 56421064 Common - phosphatidylserine synthase GK2529 154 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 56420284 Nonpathogen - hypothetical protein GK1749 1 None None None 56420248 Common - hypothetical protein GK1713 45 COG3217 COG3217, Uncharacterized Fe-S protein General function prediction only 56419737 Common rplS 50S ribosomal protein L19 GK1202 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 56420639 Common - DNA/RNA helicase GK2104 178 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 56420537 Common - hypothetical protein GK2002 3 None None None 56420893 Nonpathogen - hypothetical protein GK2358 1 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 56421513 Common - branched-chain amino acid ABC transporter (permease) GK2978 148 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 56420915 Common - butyrate kinase GK2380 130 COG3426 COG3426, Butyrate kinase Energy production and conversion 56419565 Common - long-chain fatty-acid-CoA ligase GK1030 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 56421909 Common - hypothetical protein GK3374 59 COG1971 COG1971, Predicted membrane protein Function unknown 56419026 Nonpathogen - hypothetical protein GK0491 1 None None None 56420066 Common - glycolate oxidase iron-sulfur subunit GK1531 174 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 56421452 Common - hypothetical protein GK2917 18 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 56419427 Common - hypothetical protein GK0892 19 COG4454 COG4454, Uncharacterized copper-binding protein Inorganic ion transport and metabolism 56420074 Nonpathogen - hypothetical protein GK1539 1 None None None 56420979 Common - stage V sporulation protein AF GK2444 15 None None None 56418767 Common - hypothetical protein GK0232 15 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 56419295 Common - hypothetical protein GK0760 86 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 56421307 Common - NAD-dependent aldehyde dehydrogenase GK2772 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 56420943 Common spoIIIAA stage III sporulation protein AA GK2408 34 COG3854 SpoIIIAA, ncharacterized protein conserved in bacteria Function unknown 56419115 Common - transcriptional regulator (ArsR family) GK0580 178 COG0640 ArsR, Predicted transcriptional regulators Transcription 56420212 Common - ABC transporter (ATP-binding protein) GK1677 249 COG1119 ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA Inorganic ion transport and metabolism 56420164 Nonpathogen - stage II sporulation protein AA GK1629 1 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 56421011 Common - hypothetical protein GK2476 3 None None None 56421978 Common - sucrose-6-phosphate hydrolase (Sucrase) GK3443 53 COG1621 SacC, Beta-fructosidases (levanase/invertase) Carbohydrate transport and metabolism 56419387 Common - hypothetical protein GK0852 3 None None None 56420592 Common aroD 3-dehydroquinate dehydratase GK2057 53 COG0710 AroD, 3-dehydroquinate dehydratase Amino acid transport and metabolism 56420609 Common - hypothetical protein GK2074 203 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 56421481 Common - hypothetical protein GK2946 67 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 56419441 Common ansB asparagine synthetase GK0906 173 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 56421182 Common hemA glutamyl-tRNA reductase GK2647 181 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 56421190 Common - 3-isopropylmalate dehydratase small subunit GK2655 210 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 56418916 Common - hypothetical protein GK0381 106 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 56421330 Common - thiamine biosynthesis GK2795 95 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 56420550 Common - transcriptional regulator GK2015 154 COG2186 FadR, Transcriptional regulators Transcription 56419239 Common - maltose/maltodextrin transport system (subsrate-binding protein) GK0704 104 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 56421100 Common - hypothetical protein GK2565 160 COG1959 COG1959, Predicted transcriptional regulator Transcription 56420656 Common - ABC transporter (permease) GK2121 182 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 56419164 Common - small acid-soluble spore protein GK0629 13 None None None 56420753 Common - hypothetical protein GK2218 3 None None None 56419951 Common - type III restriction-modification system, methyltransferase GK1416 94 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 56421736 Common - multidrug-efflux transporter GK3201 222 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 56418652 Common rplX 50S ribosomal protein L24 GK0117 214 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 56421398 Common - S-ribosylhomocysteinase GK2863 55 COG1854 LuxS, LuxS protein involved in autoinducer AI2 synthesis Signal transduction mechanisms 56418750 Common - sporulation-control protein GK0215 18 COG4326 Spo0M, Sporulation control protein General function prediction only 56420379 Nonpathogen - hypothetical protein GK1844 1 None None None 56420729 Common - hypothetical protein GK2194 7 COG5582 COG5582, Uncharacterized conserved protein Function unknown 56421797 Common - DNA/RNA helicase (SNF2 family) GK3262 143 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 56418871 Nonpathogen - hypothetical protein GK0336 2 None None None 56419315 Common - IS1604-like transposase GK0780 82 None None None 56421493 Common - hypothetical protein GK2958 4 COG4844 COG4844, Uncharacterized protein conserved in bacteria Function unknown 56421891 Common - NADH dehydrogenase subunit A GK3356 163 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 56420388 Common - phosphoesterase GK1853 99 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 56419936 Common - hypothetical protein GK1401 31 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 56421099 Common - iron-sulfur cofactor synthesis GK2564 239 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 56421122 Common tgt queuine tRNA-ribosyltransferase GK2587 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 56420722 Common - hypothetical protein GK2187 64 COG1284 COG1284, Uncharacterized conserved protein Function unknown 56421403 Nonpathogen - hypothetical protein GK2868 1 None None None 56418551 Common - hypothetical protein GK0016 222 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 56418794 Common - adenylosuccinate lyase GK0259 240 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 56419598 Common - hypothetical protein GK1063 2 None None None 56420359 Common - hypothetical protein GK1824 75 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 56418570 Common ksgA dimethyladenosine transferase GK0035 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 56420147 Common - dehydrogenase GK1612 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 56418861 Nonpathogen - hypothetical protein GK0326 1 None None None 56420010 Common - hypothetical protein GK1475 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 56420044 Common thiK hydroxyethylthiazole kinase GK1509 77 COG2145 ThiM, Hydroxyethylthiazole kinase, sugar kinase family Coenzyme metabolism 56419982 Common - toxic ion resistance protein GK1447 35 COG3853 TelA, Uncharacterized protein involved in tellurite resistance Inorganic ion transport and metabolism 56420352 Common - hypothetical protein GK1817 175 COG4989 COG4989, Predicted oxidoreductase General function prediction only 56421740 Common - ABC transporter (permease) GK3205 160 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 56422033 Common rpmH 50S ribosomal protein L34 GK3498 9 None None None 56418933 Common - L-lactate permease GK0398 104 COG1620 LldP, L-lactate permease Energy production and conversion 56418840 Nonpathogen - hypothetical protein GK0305 1 None None None 56421418 Nonpathogen - hypothetical protein GK2883 1 None None None 56421411 Common - menaquinone-specific isochorismate synthase GK2876 223 COG1169 MenF, Isochorismate synthase Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism 56419823 Common - hypothetical protein GK1288 191 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 56419703 Common - DNA-directed RNA polymerase omega subunit (transcriptase omega chain) GK1168 18 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 56419692 Common pyrE orotate phosphoribosyltransferase GK1157 187 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 56418799 Common - phosphoribosylpyrophosphate amidotransferase GK0264 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 56419643 Common - 2-dehydropantoate 2-reductase GK1108 91 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 56419611 Common - hypothetical protein GK1076 4 None None None 56420252 Common - hypothetical protein GK1717 123 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 56419450 Nonpathogen - hypothetical protein GK0915 1 None None None 56419501 Common - hypothetical protein GK0966 2 None None None 56419618 Common ctaD cytochrome c oxidase subunit I GK1083 169 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 56418684 Common - arginase GK0149 139 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 56418664 Common infA translation initiation factor IF-1 GK0129 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 56419477 Common - Mg-protoporphyrin IX monomethyl ester oxidative cyclase GK0942 112 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 56420567 Common - hypothetical protein GK2032 106 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 56420307 Common - hypothetical protein GK1772 2 None None None 56418946 Common - acylphosphatase GK0411 129 COG1254 AcyP, Acylphosphatases Energy production and conversion 56419087 Nonpathogen - hypothetical protein GK0552 1 None None None 56420635 Common - hypothetical protein GK2100 5 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 56420191 Common - hypothetical protein GK1656 35 COG2030 MaoC, Acyl dehydratase Lipid metabolism 56421409 Common - hypothetical protein GK2874 139 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 56421819 Common - acetyltransferase GK3284 82 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 56421442 Common - transposase GK2907 30 None None None 56420770 Common - NAD-specific glutamate dehydrogenase (NAD-GDH) GK2235 179 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 56421204 Common - transcriptional regulator (MarR family) GK2669 23 COG1846 MarR, Transcriptional regulators Transcription 56420346 Nonpathogen - hypothetical protein GK1811 4 None None None 56420347 Nonpathogen - hypothetical protein GK1812 3 None None None 56421744 Common - two-component sensor histidine kinase GK3209 107 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 56419153 Common - transcriptional regulator GK0618 78 COG0819 TenA, Putative transcription activator Transcription 56420096 Common tlp small acid-soluble spore protein Tlp GK1561 5 None None None 56419639 Common - hypothetical protein GK1104 11 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 56420624 Nonpathogen - hypothetical protein GK2089 1 None None None 56418968 Common - two-component sensor histidine kinase GK0433 148 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 56418996 Common - formate dehydrogenase accessory protein GK0461 137 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 56421959 Common - DNA-directed RNA polymerase sigma-37 factor (sigma-B) GK3424 215 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 56421854 Common - sugar transferase involved in lipopolysaccharide synthesis GK3319 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 56418958 Common - H+/Ca2+ exchanger GK0423 37 COG0387 ChaA, Ca2+/H+ antiporter Inorganic ion transport and metabolism 56421002 Nonpathogen - hypothetical protein GK2467 2 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 56421952 Common - cell wall hydrolase (sporulation) GK3417 10 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 56420143 Common - penicillin-binding protein, peptidoglycan glycosyltransferase GK1608 203 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 56421467 Common - superoxide dismutase (Cu/Zn) GK2932 87 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 56419630 Common - hypothetical protein GK1095 8 COG3679 COG3679, Uncharacterized conserved protein Function unknown 56419749 Common hslU ATP-dependent protease ATP-binding subunit GK1214 211 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 56421822 Common - hypothetical protein GK3287 51 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 56418976 Common - hypothetical protein GK0441 6 COG5609 COG5609, Uncharacterized conserved protein Function unknown 56421638 Common - hypothetical protein GK3103 50 COG1284 COG1284, Uncharacterized conserved protein Function unknown 56418815 Nonpathogen - hypothetical protein GK0280 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 56420156 Common - ABC transporter (ATP-binding protein) GK1621 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 56420091 Common - thiosulfate sulfurtransferase GK1556 142 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 56421555 Common - hypothetical protein GK3020 26 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 56420363 Common - nitrate reductase gamma subunit GK1828 58 COG2181 NarI, Nitrate reductase gamma subunit Energy production and conversion 56418908 Common - acetolactate synthase 2 catalytic subunit GK0373 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 56420748 Common mtrB transcription attenuation protein MtrB GK2213 11 None None None 56421655 Common - acylneuraminate cytidylyltransferase GK3120 101 COG1083 NeuA, CMP-N-acetylneuraminic acid synthetase Cell envelope biogenesis, outer membrane 56418783 Common groES co-chaperonin GroES GK0248 210 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 56418856 Common - transposase GK0321 7 None None None 56419699 Common - calcium-transporting ATPase GK1164 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 56419992 Common - iron(III) dicitrate ABC transporter (lipoprotein) GK1457 88 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 56419862 Common glnA glutamine synthetase (glutamate-ammonia ligase) GK1327 232 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 56421519 Common - hypothetical protein GK2984 42 COG0730 COG0730, Predicted permeases General function prediction only 56419493 Common - transcriptional regulator (MarR family) GK0958 129 COG1846 MarR, Transcriptional regulators Transcription 56419480 Common - methylated-DNA-protein-cysteine S-methyltransferase GK0945 212 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 56419679 Nonpathogen - hypothetical protein GK1144 1 None None None 56420106 Common - hypothetical protein GK1571 12 COG4479 COG4479, Uncharacterized protein conserved in bacteria Function unknown 56419218 Common - DNA repair exonuclease GK0683 122 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 56419922 Nonpathogen - hypothetical protein GK1387 1 None None None 56420769 Common - thioredoxin reductase GK2234 184 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 56420425 Common iolE myo-inositol catabolism protein GK1890 78 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 56421199 Common - hypothetical protein GK2664 76 COG0622 COG0622, Predicted phosphoesterase General function prediction only 56420572 Common - aldehyde dehydrogenase GK2037 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 56421608 Common hisH imidazole glycerol phosphate synthase subunit HisH GK3073 215 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 56419350 Common - oligopeptide ABC transporter (ATP-binding protein) GK0815 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 56419357 Common - thimet oligoendopeptidase GK0822 88 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 56421812 Common - hypothetical protein GK3277 164 COG2962 RarD, Predicted permeases General function prediction only 56420326 Common - cobalamin adenosyltransferase GK1791 139 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 56418950 Common sat sulfate adenylyltransferase GK0415 64 COG2046 MET3, ATP sulfurylase (sulfate adenylyltransferase) Inorganic ion transport and metabolism 56421758 Common - arsenic oxyanion-translocation pump GK3223 143 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 56420868 Common - ribonuclease Z GK2333 136 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 56419969 Common - hypothetical protein GK1434 106 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning