Thermus thermophilus HB8 plasmid pTT27, complete sequence NC_006462 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 55978192 Common - hypothetical protein TTHB009 33 COG3744 COG3744, Uncharacterized protein conserved in bacteria Function unknown 55978258 Common - putative C4-dicarboxylate transporter, small permease protein TTHB075 25 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 55978332 Common - hypothetical protein TTHB149 30 COG1337 COG1337, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 55978263 Common - 2-deoxy-D-gluconate 3-dehydrogenase TTHB080 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 55978190 Nonpathogen - hypothetical protein TTHB007 1 COG2929 COG2929, Uncharacterized protein conserved in bacteria Function unknown 55978366 Common - hypothetical protein TTHB183 19 None None None 55978279 Nonpathogen - hypothetical protein TTHB096 2 None None None 55978242 Common - hypothetical protein TTHB059 2 None None None 55978411 Common - hypothetical protein TTHB228 2 None None None 55978210 Nonpathogen - hypothetical protein TTHB027 5 COG5184 ATS1, Alpha-tubulin suppressor and related RCC1 domain-containing proteins Cell division and chromosome partitioning / Cytoskeleton 55978219 Common - probable sugar transporter TTHB036 14 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 55978354 Common - hypothetical protein TTHB171 21 None None None 55978311 Common - arsenite oxidase, small subunit TTHB128 44 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 55978381 Nonpathogen - hypothetical protein TTHB198 1 None None None 55978432 Common - phenol hydroxylase component A TTHB249 50 COG2368 COG2368, Aromatic ring hydroxylase Secondary metabolites biosynthesis, transport, and catabolism 55978253 Common - survival protein SurE TTHB070 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 55978197 Common - probable phosphotransferase TTHB014 59 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 55978317 Nonpathogen - hypothetical protein TTHB134 1 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 55978396 Common - hypothetical protein TTHB213 17 None None None 55978348 Common - hypothetical protein TTHB165 22 COG1604 COG1604, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 55978327 Nonpathogen - hypothetical protein TTHB144 5 None None None 55978268 Common - sugar ABC transporter, permease protein TTHB085 144 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 55978403 Common - hemin ABC transporter, periplasmic hemin-binding protein TTHB220 111 COG4558 ChuT, ABC-type hemin transport system, periplasmic component Inorganic ion transport and metabolism 55978423 Common - 5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase TTHB240 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 55978293 Common - isopentenyl pyrophosphate isomerase TTHB110 80 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 55978303 Nonpathogen - hypothetical protein TTHB120 2 None None None 55978231 Common - nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase TTHB048 117 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 55978301 Nonpathogen - probable secretion system protein TTHB118 1 COG4967 PilV, Tfp pilus assembly protein PilV Cell motility and secretion / Intracellular trafficking and secretion 55978296 Common - hypothetical protein TTHB113 16 None None None 55978419 Nonpathogen - hypothetical protein TTHB236 1 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 55978215 Common - putative beta-galactosidase TTHB032 48 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 55978383 Common - transposase-like protein TTHB200 80 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 55978275 Common - probable phytoene dehydrogenase TTHB092 12 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 55978310 Common - arsenite oxidase, large subunit TTHB127 166 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 55978339 Nonpathogen - hypothetical protein TTHB156 1 None None None 55978212 Common - hypothetical protein TTHB029 7 COG3394 COG3394, Uncharacterized protein conserved in bacteria Function unknown 55978400 Nonpathogen - hypothetical protein TTHB217 1 None None None 55978407 Common - hypothetical protein TTHB224 98 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 55978282 Common - transcriptional regulator, Crp family TTHB099 83 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 55978340 Nonpathogen - hypothetical protein TTHB157 1 None None None 55978413 Common - putative ATP-dependent RNA helicase TTHB230 82 COG1203 COG1203, Predicted helicases General function prediction only 55978376 Common - hypothetical protein TTHB193 51 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 55978273 Common - hypothetical protein TTHB090 20 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 55978392 Common - ribonucleotide-diphosphate reductase subunit alpha TTHB209 218 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 55978398 Common - hypothetical protein TTHB215 49 COG3488 COG3488, Predicted thiol oxidoreductase Energy production and conversion 55978291 Common - plasmid stability protein TTHB108 63 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 55978251 Nonpathogen - hypothetical protein TTHB068 5 COG1431 COG1431, Uncharacterized protein containing piwi/argonaute domain Translation, ribosomal structure and biogenesis 55978338 Nonpathogen - hypothetical protein TTHB155 1 None None None 55978225 Nonpathogen - hypothetical protein TTHB042 1 None None None 55978368 Nonpathogen - hypothetical protein TTHB185 1 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 55978315 Common - methionine sulfoxide reductase A TTHB132 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 55978405 Common - hypothetical protein TTHB222 48 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 55978346 Common - hypothetical protein TTHB163 33 COG1336 COG1336, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 55978289 Common - probable glycosyltransferase TTHB106 41 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 55978222 Nonpathogen - hypothetical protein TTHB039 1 None None None 55978425 Common - 4-oxalocrotonate tautomerase TTHB242 21 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 55978233 Common - probable high-affinity nickel permease TTHB050 9 COG3376 HoxN, High-affinity nickel permease Inorganic ion transport and metabolism 55978355 Common - reverse gyrase TTHB172 230 COG1110 COG1110, Reverse gyrase DNA replication, recombination, and repair 55978417 Nonpathogen - hypothetical protein TTHB234 1 None None None 55978265 Common - sugar ABC transporter, periplasmic sugar-binding protein TTHB082 95 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 55978247 Nonpathogen - hypothetical protein TTHB064 2 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 55978204 Common - hypothetical protein TTHB021 29 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 55978325 Common - glycerol kinase TTHB142 175 COG0554 GlpK, Glycerol kinase Energy production and conversion 55978430 Common - acetaldehyde dehydrogenase TTHB247 37 COG4569 MhpF, Acetaldehyde dehydrogenase (acetylating) Secondary metabolites biosynthesis, transport, and catabolism 55978337 Common - transposase TTHB154 72 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 55978342 Nonpathogen - hypothetical protein TTHB159 1 None None None 55978306 Nonpathogen - hypothetical protein TTHB123 1 None None None 55978280 Nonpathogen - hypothetical protein TTHB097 1 None None None 55978187 Common - probable transposase TTHB004 41 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 55978295 Common - hypothetical protein TTHB112 51 COG1683 COG1683, Uncharacterized conserved protein Function unknown 55978195 Common - phosphoglycerate mutase family protein TTHB012 93 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 55978270 Common - beta-glucosidase TTHB087 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 55978217 Common - putative beta-mannosidase TTHB034 71 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 55978201 Common - hypothetical protein TTHB018 60 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 55978227 Common - cob(I)alamin adenosyltransferase TTHB044 142 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 55978420 Common - 2-hydroxymuconic semialdehyde hydrolase TTHB237 131 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 55978207 Common - hypothetical protein TTHB025 43 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 55978415 Common - transposase TTHB232 82 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 55978314 Nonpathogen - hypothetical protein TTHB131 1 None None None 55978245 Common - cobalamin biosynthesis protein CbiB TTHB062 35 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 55978267 Common - transposase TTHB084 82 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 55978297 Common - galactose-1-phosphate uridylyltransferase TTHB114 78 COG1085 GalT, Galactose-1-phosphate uridylyltransferase Energy production and conversion 55978427 Common - phenol hydroxylase component B TTHB244 75 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 55978384 Common - transposase-like protein TTHB201 76 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 55978324 Common - putative glycerophosphoryl diester phosphodiesterase TTHB141 80 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 55978369 Common - putative transcriptional regulator TTHB186 38 COG2378 COG2378, Predicted transcriptional regulator Transcription 55978257 Common - putative C4-dicarboxylate transporter, periplasmic C4-dicarboxylate-binding protein TTHB074 101 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 55978223 Nonpathogen - hypothetical protein TTHB040 5 None None None 55978406 Common - hypothetical protein TTHB223 9 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 55978357 Common - sensor histidine kinase-like protein TTHB174 8 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 55978350 Nonpathogen - hypothetical protein TTHB167 1 None None None 55978287 Nonpathogen - phytoene synthase-related protein TTHB104 7 None None None 55978220 Nonpathogen - hypothetical protein TTHB037 2 COG3947 COG3947, Response regulator containing CheY-like receiver and SARP domains Signal transduction mechanisms 55978236 Common - precorrin-6Y C5,15-methyltransferase [decarboxylating] TTHB053 109 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 55978370 Common - hypothetical protein TTHB187 42 COG1203 COG1203, Predicted helicases General function prediction only 55978393 Nonpathogen - hypothetical protein TTHB210 2 None None None 55978362 Nonpathogen - hypothetical protein TTHB179 2 COG4719 COG4719, Uncharacterized protein conserved in bacteria Function unknown 55978335 Nonpathogen - hypothetical protein TTHB152 4 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 55978193 Nonpathogen - transposase-related protein TTHB010 2 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 55978285 Common - DNA photolyase TTHB102 131 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 55978373 Common - hypothetical protein TTHB190 42 None None None 55978229 Nonpathogen - cobalamin (5'-phosphate) synthase TTHB046 1 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 55978344 Common - hypothetical protein TTHB161 13 COG1769 COG1769, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 55978203 Common - 3-oxoacyl-[acyl carrier protein] reductase TTHB020 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 55978387 Nonpathogen - hypothetical protein TTHB204 1 None None None 55978328 Common - hypothetical protein TTHB145 87 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 55978334 Nonpathogen - hypothetical protein TTHB151 3 COG1332 COG1332, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 55978330 Common - hypothetical protein TTHB147 25 COG1353 COG1353, Predicted hydrolase of the HD superfamily (permuted catalytic motifs) General function prediction only 55978185 Nonpathogen - hypothetical protein TTHB002 4 None None None 55978380 Common - probable formate dehydrogenase TTHB197 180 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 55978260 Common - oxidoreductase, short-chain dehydrogenase/reductase family TTHB077 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 55978351 Nonpathogen - hypothetical protein TTHB168 2 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 55978429 Common - 4-hydroxy-2-ketovalerate aldolase TTHB246 168 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 55978329 Common - transposase TTHB146 73 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 55978322 Common - permease of the major facilitator superfamily TTHB139 135 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 55978241 Common - cobalamin biosynthesis protein CbiX TTHB058 32 COG2138 COG2138, Uncharacterized conserved protein Function unknown 55978385 Common - hypothetical protein TTHB202 23 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 55978208 Nonpathogen - hypothetical protein TTHB024 1 None None None 55978238 Common - precorrin-4 C11-methyltransferase TTHB055 191 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 55978364 Common - hypothetical protein TTHB181 8 None None None 55978312 Common - transposase TTHB129 82 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 55978365 Nonpathogen - hypothetical protein TTHB182 9 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 55978191 Common - hypothetical protein TTHB008 3 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 55978277 Nonpathogen - putative short-chain oxidoreductase TTHB094 2 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 55978319 Nonpathogen - probable transcriptional regulator, CopG family TTHB136 1 None None None 55978371 Common - comserved hypothetical protein TTHB188 18 None None None 55978255 Common - 4-hydroxy-2-oxoglutarate aldolase/2-deydro-3-deoxyphosphogluconate aldolase TTHB072 125 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 55978408 Common - hypothetical protein TTHB225 51 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 55978401 Common - ABC transporter, ATP-binding protein TTHB218 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 55978347 Nonpathogen - hypothetical protein TTHB164 3 COG3337 COG3337, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 55978402 Common - hemin ABC transporter, permease protein TTHB219 164 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 55978290 Common - hypothetical protein TTHB107 15 None None None 55978269 Common - sugar ABC transporter, permease protein TTHB086 144 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 55978252 Common - hypothetical protein TTHB069 10 COG1553 DsrE, Uncharacterized conserved protein involved in intracellular sulfur reduction Inorganic ion transport and metabolism 55978395 Nonpathogen - hypothetical protein TTHB212 3 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 55978318 Nonpathogen - hypothetical protein TTHB135 1 COG4113 COG4113, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 55978375 Common - hypothetical protein TTHB192 22 None None None 55978278 Nonpathogen - hypothetical protein TTHB095 3 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 55978243 Common - S-adenosyl-L-methionine uroporphyrinogen methyltransferase TTHB060 202 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 55978422 Common - 2-oxopent-4-dienoate hydratase TTHB239 68 COG3971 COG3971, 2-keto-4-pentenoate hydratase Secondary metabolites biosynthesis, transport, and catabolism 55978326 Common - putative glycerol-3-phohsphate dehydrogenase TTHB143 148 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 55978205 Common - putative acyl-CoA dehydrogenase TTHB022 166 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 55978230 Nonpathogen - hypothetical protein TTHB047 1 None None None 55978320 Common - hypothetical protein TTHB137 7 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 55978239 Common - precorrin-3 C17-methyltransferase TTHB056 169 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 55978274 Nonpathogen - hypothetical protein TTHB091 1 COG2267 PldB, Lysophospholipase Lipid metabolism 55978433 Common - metapyrocatechase (catechol 2,3-dioxygenase) TTHB250 38 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 55978374 Common - hypothetical protein TTHB191 36 None None None 55978331 Nonpathogen - hypothetical protein TTHB148 1 None None None 55978184 Nonpathogen - hypothetical protein TTHB001 1 None None None 55978248 Common - cobalamin biosynthesis aminotransferase TTHB065 175 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 55978283 Common - transcriptional regulator, MerR family TTHB100 53 COG0789 SoxR, Predicted transcriptional regulators Transcription 55978388 Nonpathogen - hypothetical protein TTHB205 1 None None None 55978353 Nonpathogen - hypothetical protein TTHB170 4 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 55978211 Nonpathogen - hypothetical protein TTHB028 3 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 55978367 Nonpathogen - hypothetical protein TTHB184 1 None None None 55978272 Common - hypothetical protein TTHB089 13 None None None 55978390 Common - hypothetical protein TTHB207 142 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 55978391 Common - ribonucleoside-diphosphate reductase, beta subunit TTHB208 36 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 55978360 Common - iron ABC transporter, periplasmic iron-binding protein TTHB177 53 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 55978377 Common - hypothetical protein TTHB194 28 None None None 55978198 Common - putative acyl-CoA dehydrogenase TTHB015 145 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 55978299 Common - acyl-CoA dehydrogenase, short-chain specific (probable AidB protein) TTHB116 144 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 55978345 Nonpathogen - hypothetical protein TTHB162 12 COG1367 COG1367, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 55978262 Common - 2-keto-3-deoxy-gluconate kinase TTHB079 183 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 55978250 Common - alkaline phosphatase TTHB067 85 COG1785 PhoA, Alkaline phosphatase Inorganic ion transport and metabolism 55978288 Nonpathogen - putative acyltransferase TTHB105 2 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 55978397 Nonpathogen - hypothetical proteih TTHB214 2 None None None 55978404 Nonpathogen - hypothetical protein TTHB221 4 None None None 55978308 Common - chromosome partitioning ATPase, ParA family TTHB125 196 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 55978224 Nonpathogen - hypothetical protein TTHB041 1 None None None 55978232 Common - alpha-ribazole-5'-phosphate phosphatase TTHB049 179 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 55978356 Common - response regulator TTHB173 48 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 55978246 Common - hypothetical protein TTHB063 15 COG2250 COG2250, Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN Function unknown 55978416 Nonpathogen - hypothetical protein TTHB233 2 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 55978424 Common - 4-oxalocrotonate decarboxylase TTHB241 53 COG3971 COG3971, 2-keto-4-pentenoate hydratase Secondary metabolites biosynthesis, transport, and catabolism 55978382 Nonpathogen - hypothetical protein TTHB199 2 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 55978309 Nonpathogen - hypothetical protein TTHB126 2 COG5534 COG5534, Plasmid replication initiator protein DNA replication, recombination, and repair 55978218 Nonpathogen - hypothetical protein TTHB035 1 None None None 55978189 Nonpathogen - hypothetical protein TTHB006 1 None None None 55978302 Nonpathogen - prepilin-like protein TTHB119 1 COG4795 PulJ, Type II secretory pathway, component PulJ Intracellular trafficking and secretion 55978281 Common - NADH-ubiquinone oxidoreductase 39 kDa subunit related protein TTHB098 125 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 55978259 Common - putative C4-dicarboxylate transporter, large permease protein TTHB076 128 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 55978234 Common cbiD cobalt-precorrin-6A synthase TTHB051 81 COG1903 CbiD, Cobalamin biosynthesis protein CbiD Coenzyme metabolism 55978316 Common - hypothetical protein TTHB133 75 COG3189 COG3189, Uncharacterized conserved protein Function unknown 55978410 Common - hypothetical protein TTHB227 2 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 55978213 Common - probable sugar transporter TTHB030 55 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 55978226 Common - cobyrinic acid a,c-diamide synthase TTHB043 136 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 55978389 Nonpathogen - hypothetical protein TTHB206 1 None None None 55978244 Common - cobalamin biosynthesis nitroreductase BluB TTHB061 104 COG0778 NfnB, Nitroreductase Energy production and conversion 55978414 Common - hypothetical protein TTHB231 9 COG5551 COG5551, Uncharacterized conserved protein Function unknown 55978409 Nonpathogen - hypothetical protein TTHB226 19 COG2378 COG2378, Predicted transcriptional regulator Transcription 55978426 Nonpathogen - hypothetical protein TTHB243 1 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 55978206 Common - transcriptional regulator, TetR family TTHB023 161 COG1309 AcrR, Transcriptional regulator Transcription 55978235 Common - cobalamin biosynthesis precorrin-8X isomerase TTHB052 119 COG2082 CobH, Precorrin isomerase Coenzyme metabolism 55978209 Nonpathogen - hypothetical protein TTHB026 1 None None None 55978358 Common - ABC transporter, ATP-binding protein TTHB175 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 55978221 Nonpathogen - hypothetical protein TTHB038 1 None None None 55978286 Common - cytochrome P450 (Cyp175a1) TTHB103 69 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 55978256 Common - transcriptional regulator TTHB073 124 COG1414 IclR, Transcriptional regulator Transcription 55978399 Common - ABC transporter, periplasmic solute-binding protein-related protein TTHB216 47 COG4594 FecB, ABC-type Fe3+-citrate transport system, periplasmic component Inorganic ion transport and metabolism 55978361 Common - hypothetical protein TTHB178 26 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 55978264 Common - transcriptional regulator, lacI family TTHB081 126 COG1609 PurR, Transcriptional regulators Transcription 55978378 Common - hypothetical protein TTHB195 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 55978349 Nonpathogen - hypothetical protein TTHB166 1 None None None 55978336 Nonpathogen - hypothetical protein TTHB153 1 None None None 55978418 Common - hypothetical protein TTHB235 18 None None None 55978431 Common - transcriptional regulator, IclR family TTHB248 121 COG1414 IclR, Transcriptional regulator Transcription 55978214 Nonpathogen - probable sugar transporter TTHB031 1 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 55978307 Common - chromosome partitioning protein, ParB family TTHB124 183 COG1475 Spo0J, Predicted transcriptional regulators Transcription 55978341 Nonpathogen - hypothetical protein TTHB158 1 None None None 55978298 Common - alpha-galactosidase TTHB115 46 COG3345 GalA, Alpha-galactosidase Carbohydrate transport and metabolism 55978294 Nonpathogen - hypothetical protein TTHB111 4 None None None 55978188 Nonpathogen - probable transposase TTHB005 7 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 55978228 Common - repeat motif-containing protein TTHB045 65 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 55978300 Nonpathogen - putative type IV pilin TTHB117 1 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 55978323 Common - hypothetical protein TTHB140 17 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 55978200 Common - medium-chain acyl-CoA ligase-related protein TTHB017 220 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 55978428 Common - hypothetical protein TTHB245 162 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 55978412 Common - hypothetical protein TTHB229 2 None None None 55978271 Common - Zn-dependent hydrolase TTHB088 64 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 55978196 Nonpathogen - hypothetical protein TTHB013 1 None None None 55978237 Common - precorrin-2 methylase TTHB054 60 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 55978261 Common - malate/L-lactate dehydrogenase family protein TTHB078 67 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 55978421 Nonpathogen - hypothetical protein TTHB238 1 None None None 55978321 Common - hypothetical protein TTHB138 141 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 55978313 Common - putative transcriptional regulator TTHB130 99 COG0640 ArsR, Predicted transcriptional regulators Transcription 55978352 Common - hypothetical protein TTHB169 12 COG5611 COG5611, Predicted nucleic-acid-binding protein, contains PIN domain General function prediction only 55978240 Common - cobalamin biosynthesis protein CbiG TTHB057 93 COG2073 CbiG, Cobalamin biosynthesis protein CbiG Coenzyme metabolism 55978363 Common - hypothetical protein TTHB180 29 COG1470 COG1470, Predicted membrane protein Function unknown 55978194 Nonpathogen - probable transposase TTHB011 1 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 55978276 Common - putative oxidoreductase TTHB093 50 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 55978199 Common - gluconate 5-dehydrogenase TTHB016 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 55978292 Common - phytoene dehydrogenase TTHB109 94 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 55978379 Common - putative protein required for formate dehydrogenase activity TTHB196 137 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 55978434 Nonpathogen - ABC transporter, periplasmic solute-binding protein-related protein TTHB251 4 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 55978249 Common - cobyric acid synthase/cobinamide kinase TTHB066 158 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 55978304 Common - resolvase-related protein TTHB121 19 COG2452 COG2452, Predicted site-specific integrase-resolvase DNA replication, recombination, and repair 55978266 Common - sugar ABC transporter, permease protein TTHB083 110 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 55978284 Common - phytoene synthase TTHB101 102 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 55978372 Common - hypothetical protein TTHB189 10 None None None 55978359 Common - putative iron ABC transporter, permease protein TTHB176 189 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 55978394 Common - putative RNA polymerase sigma factor TTHB211 94 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 55978216 Common - alpha-glucosidase TTHB033 82 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 55978254 Nonpathogen - hypothetical protein TTHB071 7 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 55978202 Common - MaoC-related acyl dehydratase TTHB019 120 COG2030 MaoC, Acyl dehydratase Lipid metabolism 55978386 Nonpathogen - hypothetical protein TTHB203 1 None None None 55978333 Nonpathogen - hypothetical protein TTHB150 4 COG1567 COG1567, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 55978343 Common - hypothetical protein TTHB160 21 COG1353 COG1353, Predicted hydrolase of the HD superfamily (permuted catalytic motifs) General function prediction only 55978186 Nonpathogen - hypothetical protein TTHB003 1 None None None 55978305 Nonpathogen - hypothetical protein TTHB122 4 None None None