Thermus thermophilus HB8, complete genome NC_006461 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 55981702 Common - copper-transporting ATPase, P-type (CopB) TTHA1733 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 55981329 Common - hypothetical protein TTHA1360 62 COG2928 COG2928, Uncharacterized conserved protein Function unknown 55981134 Common - phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase TTHA1165 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 55980828 Common - uridylate kinase TTHA0859 246 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 55980543 Common - probable DNA polymerase III epsilon subunit TTHA0574 142 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 55980283 Nonpathogen - hypothetical protein TTHA0314 3 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 55981856 Common - CAIB/BAIF family protein TTHA1887 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 55981646 Common rplF 50S ribosomal protein L6 TTHA1677 226 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 55981330 Nonpathogen - hypothetical protein TTHA1361 1 None None None 55980619 Common - putative phosphoglucomutase/phosphomannomutase TTHA0650 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 55981145 Nonpathogen - hypothetical protein TTHA1176 3 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 55980497 Common - ADP-ribose pyrophosphatase TTHA0528 107 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 55980030 Nonpathogen - hypothetical protein TTHA0061 2 None None None 55981140 Common - amino acid ABC transporter, periplasmic amino acid-binding protein TTHA1171 188 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 55980026 Common - nitrogen regulatory protein P-II TTHA0057 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 55980056 Common - NADH-quinone oxidoreductase chain 4 TTHA0087 192 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 55980690 Nonpathogen - hypothetical protein TTHA0721 2 None None None 55980126 Common - probable NADH-dependent flavin oxidoreductase TTHA0157 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 55980641 Common - probable sulfite reductase TTHA0672 169 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 55980295 Common - putative ATP/GTP-binding integral membrane protein TTHA0326 14 COG1485 COG1485, Predicted ATPase General function prediction only 55981515 Common - thioesterase family protein TTHA1546 100 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 55980941 Common - phenylacetic acid degradation protein PaaA TTHA0972 45 COG3396 COG3396, Uncharacterized conserved protein Function unknown 55981333 Common - hypothetical protein TTHA1364 21 COG4127 COG4127, Uncharacterized conserved protein Function unknown 55981088 Common - hypothetical protein TTHA1119 27 COG1963 COG1963, Uncharacterized protein conserved in bacteria Function unknown 55981097 Common - probable peptidase TTHA1128 57 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 55980008 Nonpathogen - hypothetical protein TTHA0039 1 None None None 55980016 Nonpathogen - probable nucleotidyltransferase TTHA0047 1 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 55980948 Nonpathogen - hypothetical protein TTHA0979 10 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 55980024 Common - ATP-dependent DNA helicase RecG-related protein TTHA0055 67 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 55980113 Nonpathogen - sensor histidine kinase TTHA0144 7 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 55980511 Common - ATP-dependent Clp protease, ATP-binding subunit (ClpA) TTHA0542 223 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 55980553 Nonpathogen - hypothetical protein TTHA0584 1 None None None 55980759 Common - putative acetyltransferase TTHA0790 13 COG0456 RimI, Acetyltransferases General function prediction only 55980038 Common - ABC transporter, periplasmic binding protein TTHA0069 62 COG2998 TupB, ABC-type tungstate transport system, permease component Coenzyme metabolism 55980481 Nonpathogen - hypothetical protein TTHA0512 10 COG2152 COG2152, Predicted glycosylase Carbohydrate transport and metabolism 55981350 Nonpathogen - competence protein PilO TTHA1381 2 COG3167 PilO, Tfp pilus assembly protein PilO Cell motility and secretion / Intracellular trafficking and secretion 55980849 Nonpathogen - multidrug resistance protein-related protein TTHA0880 2 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 55980972 Common - sensor histidine kinase TTHA1003 199 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 55980154 Common aceE pyruvate dehydrogenase subunit E1 TTHA0185 142 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 55980654 Common - sugar ABC transporter, permease protein TTHA0685 156 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 55980915 Nonpathogen - hypothetical protein TTHA0946 1 None None None 55981069 Nonpathogen - hypothetical protein TTHA1100 2 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 55980871 Common smpB SsrA-binding protein TTHA0902 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 55980436 Nonpathogen - hypothetical protein TTHA0467 1 None None None 55981105 Nonpathogen - hypothetical protein TTHA1136 1 None None None 55981871 Common - hypothetical protein TTHA1902 35 COG1543 COG1543, Uncharacterized conserved protein Function unknown 55980208 Common - lipoyl synthase TTHA0239 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 55981665 Common - 30S ribosomal protein S7 TTHA1696 248 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 55980399 Common hisH imidazole glycerol phosphate synthase subunit HisH TTHA0430 215 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 55981185 Nonpathogen - prepilin-like protein TTHA1216 1 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 55980161 Nonpathogen - hypothetical protein TTHA0192 5 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 55980197 Common - hypothetical protein TTHA0228 123 COG1576 COG1576, Uncharacterized conserved protein Function unknown 55981709 Common - glycerol-3-phosphate dehydrogenase TTHA1740 211 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 55980261 Common - probable hydrolase TTHA0292 113 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 55980080 Nonpathogen - hypothetical protein TTHA0111 16 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 55980869 Nonpathogen - hypothetical protein TTHA0900 1 None None None 55981163 Nonpathogen - hypothetical protein TTHA1194 1 None None None 55980095 Nonpathogen - hypothetical protein TTHA0126 1 None None None 55980562 Common - probable thiol-disulfide isomerase/thioredoxin TTHA0593 66 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 55981857 Common - ABC transporter, ATP-binding protein TTHA1888 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 55980099 Common dcd deoxycytidine triphosphate deaminase TTHA0130 153 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 55980370 Nonpathogen - hypothetical protein TTHA0401 5 COG3255 COG3255, Putative sterol carrier protein Lipid metabolism 55980250 Common - hypothetical protein TTHA0281 8 COG1598 COG1598, Uncharacterized conserved protein Function unknown 55981605 Common - Xaa-pro aminopeptidase TTHA1636 139 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 55980168 Common - type B carboxylesterase TTHA0199 61 COG2272 PnbA, Carboxylesterase type B Lipid metabolism 55980591 Common - transcription elongation factor GreA TTHA0622 204 COG0782 GreA, Transcription elongation factor Transcription 55980728 Common - homoserine O-acetyltransferase TTHA0759 143 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 55981209 Common - spermidine/putrescine ABC transporter, ATP-binding protein TTHA1240 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 55981116 Nonpathogen - hypothetical protein TTHA1147 1 None None None 55981034 Common rho transcription termination factor Rho TTHA1065 203 COG1158 Rho, Transcription termination factor Transcription 55980069 Common - UDP-N-acetylmuramoylalanyl-D-glutamate--2,6- diaminopimelate ligase TTHA0100 209 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 55980955 Common - hypothetical protein TTHA0986 105 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 55980606 Common - hypothetical protein TTHA0637 21 COG4867 COG4867, Uncharacterized protein with a von Willebrand factor type A (vWA) domain General function prediction only 55981175 Nonpathogen - hypothetical protein TTHA1206 15 COG4587 COG4587, ABC-type uncharacterized transport system, permease component General function prediction only 55980427 Common - cytidylate kinase TTHA0458 201 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 55980257 Common - 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) TTHA0288 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 55980570 Common - uroporphyrinogen decarboxylase (HemE) TTHA0601 184 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 55981500 Common - hypothetical protein TTHA1531 87 COG0585 COG0585, Uncharacterized conserved protein Function unknown 55980708 Common - L-serine dehydratase, beta subunit TTHA0739 105 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 55981507 Common - putative oxidoreductase-like protein TTHA1538 68 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 55980674 Common - transcriptional repressor SmtB TTHA0705 113 COG0640 ArsR, Predicted transcriptional regulators Transcription 55981019 Common - shikimate 5-dehydrogenase TTHA1050 224 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 55980635 Common sat sulfate adenylyltransferase TTHA0666 64 COG2046 MET3, ATP sulfurylase (sulfate adenylyltransferase) Inorganic ion transport and metabolism 55981658 Common rplB 50S ribosomal protein L2 TTHA1689 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 55981495 Common - hydroxymethylglutaryl-CoA lyase like protein TTHA1526 88 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 55980878 Common - probable ornithine aminotransferase TTHA0909 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 55980580 Common - hypothetical protein TTHA0611 20 COG3870 COG3870, Uncharacterized protein conserved in bacteria Function unknown 55980761 Common - hypothetical protein TTHA0792 155 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 55981278 Nonpathogen - hypothetical protein TTHA1309 9 COG3369 COG3369, Uncharacterized conserved protein Function unknown 55980340 Common - probable serine/threonine-protein kinase TTHA0371 39 COG2815 COG2815, Uncharacterized protein conserved in bacteria Function unknown 55981206 Common - spermidine/putrescine ABC transporter, periplasmic spermidine/putrescine-binding protein TTHA1237 125 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 55980210 Common - oxidoreductase, short-chain dehydrogenase/reductase family TTHA0241 229 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 55980598 Common - putative O-linked GlcNAc transferase (TPR repeat) TTHA0629 120 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 55981868 Common - hypothetical protein TTHA1899 131 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 55981100 Nonpathogen - probable gliding protein (MglB) TTHA1131 11 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 55980488 Common - hypothetical protein TTHA0519 159 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 55980474 Common - glycolate oxidase subunit TTHA0505 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 55980813 Nonpathogen - CAAX amino terminal protease family protein TTHA0844 1 COG4449 COG4449, Predicted protease of the Abi (CAAX) family General function prediction only 55980833 Common - hypothetical protein TTHA0864 14 COG1610 COG1610, Uncharacterized conserved protein Function unknown 55981615 Nonpathogen - hypothetical protein TTHA1646 1 None None None 55981288 Nonpathogen - probable acetyltransferase TTHA1319 1 COG0456 RimI, Acetyltransferases General function prediction only 55981766 Common - probable amidase TTHA1797 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 55981041 Common - translation initiation factor, aIF-2B alpha subunit-related protein TTHA1072 128 COG0182 COG0182, Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 55980176 Common - nicotinamide nucleotide transhydrogenase, alpha subunit 2 TTHA0207 114 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 55980548 Common - sugar ABC transportor, ATP-binding protein TTHA0579 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 55981884 Common - probable undecaprenyl pyrophosphate synthetase TTHA1915 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 55980140 Common - 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase TTHA0171 196 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 55981527 Common - MarC family integral membrane protein TTHA1558 157 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 55980407 Common - glutamyl-tRNA synthetase TTHA0438 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 55980739 Common - ATP-dependent protease La (Lon protease) TTHA0770 198 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 55980535 Common - GTP-binding protein HflX TTHA0566 210 COG2262 HflX, GTPases General function prediction only 55981824 Common - ABC transporter, permease protein TTHA1855 96 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 55981302 Nonpathogen - hypothetical protein TTHA1333 1 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 55981511 Common - probable cell cycle protein MesJ TTHA1542 228 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 55981638 Common - translation initiation factor 1 (IF-1) TTHA1669 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 55981754 Common - hypothetical protein TTHA1785 118 COG1690 RtcB, Uncharacterized conserved protein Function unknown 55981723 Nonpathogen - hypothetical protein TTHA1754 1 None None None 55981811 Common - anthranilate phosphoribosyltransferase (TrpD) TTHA1842 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 55980147 Nonpathogen - hypothetical protein TTHA0178 1 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 55981441 Common - Na(+)/H(+) antiporter TTHA1472 207 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 55981733 Common - molybdopterin oxidoreductase, iron-sulfur binding subunit TTHA1764 135 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 55981271 Common - sugar ABC transporter, permease protein TTHA1302 70 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 55980402 Nonpathogen - hypothetical protein TTHA0433 1 None None None 55980697 Common - hypothetical protein TTHA0728 13 COG5153 CVT17, Putative lipase essential for disintegration of autophagic bodies inside the vacuole Intracellular trafficking and secretion / Lipid metabolism 55981761 Nonpathogen - hypothetical protein TTHA1792 1 COG2383 COG2383, Uncharacterized conserved protein Function unknown 55981432 Common - long-chain-fatty-acid--CoA ligase TTHA1463 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 55980863 Common - 33 kDa chaperonin (Heat shock protein 33 homolog) (HSP33) TTHA0894 73 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 55981715 Common - fatty acid/phospholipid synthesis protein TTHA1746 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 55980775 Nonpathogen - hypothetical protein TTHA0806 2 COG2862 COG2862, Predicted membrane protein Function unknown 55981887 Nonpathogen - hypothetical protein TTHA1918 1 None None None 55981457 Nonpathogen - DafA protein (DnaK-DnaJ assembly factor A) TTHA1488 1 None None None 55980245 Common - probable acyl-CoA synthetase TTHA0276 140 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 55981830 Common - probable phosphatase TTHA1861 71 COG0622 COG0622, Predicted phosphoesterase General function prediction only 55980082 Nonpathogen - hypothetical protein TTHA0113 5 None None None 55981558 Common - 50S ribosomal protein L25/general stress protein Ctc TTHA1589 166 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 55980926 Common - dihydrodipicolinate synthase TTHA0957 232 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 55980133 Common - thiol:disulfide interchange protein TTHA0164 53 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 55980157 Common - nucleoside diphosphate kinase TTHA0188 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 55980391 Common - UDP-N-acetyl-D-mannosaminuronic acid transferase TTHA0422 109 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 55980621 Nonpathogen - hypothetical protein TTHA0652 1 None None None 55981717 Common - hypothetical protein TTHA1748 171 COG1098 VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) Translation, ribosomal structure and biogenesis 55981890 Nonpathogen - hypothetical protein TTHA1921 1 None None None 55980225 Common - leucine aminopeptidase TTHA0256 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 55981841 Nonpathogen - hypothetical protein TTHA1872 1 None None None 55981139 Common - amino acid ABC transporter, permease protein TTHA1170 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 55981388 Common - putative cytochrome c precursor TTHA1419 31 COG3258 COG3258, Cytochrome c Energy production and conversion 55980818 Nonpathogen - hypothetical protein TTHA0849 2 COG5637 COG5637, Predicted integral membrane protein Function unknown 55980614 Common - putative glycosyltransferase TTHA0645 59 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 55980567 Nonpathogen - putative transport integral membrane protein (chloride channel) TTHA0598 2 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 55980389 Common - putative flavoprotein TTHA0420 51 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 55980921 Common - D-3-phosphoglycerate dehydrogenase TTHA0952 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 55980852 Common - probable transposase TTHA0883 41 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 55980652 Common - probable TolR-type transport protein TTHA0683 11 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 55981012 Nonpathogen - hypothetical protein TTHA1043 1 None None None 55980633 Common - NADPH quinone oxidoreductase TTHA0664 90 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 55980411 Common - probable DNA/RNA-binding protein (Jag-related protein) TTHA0442 56 COG1847 Jag, Predicted RNA-binding protein General function prediction only 55980325 Common - ABC transporter, periplasmic substrate-binding protein TTHA0356 84 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 55981120 Nonpathogen - hypothetical protein TTHA1151 1 None None None 55980877 Common - probable thioesterase TTHA0908 130 COG0824 FcbC, Predicted thioesterase General function prediction only 55981127 Common - hypothetical protein TTHA1158 65 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 55980300 Common - histidinol-phosphatase TTHA0331 37 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 55981798 Common - hypothetical protein TTHA1829 122 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 55981215 Common - methylmalonyl-CoA mutase TTHA1246 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 55981563 Common - serine/threonine protein kinase TTHA1594 156 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 55981048 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate--D-alanyl-D-alanyl ligase TTHA1079 200 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 55980958 Common - GGDEF domain protein TTHA0989 176 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 55980117 Common - ribosomal large subunit pseudouridine synthase B TTHA0148 203 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 55980786 Common - CBS domain protein TTHA0817 132 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 55981224 Nonpathogen - hypothetical protein TTHA1255 2 None None None 55980895 Common - dephospho-CoA kinase (dephosphocoenzyme A kinase) TTHA0926 147 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 55980194 Common - biotin operon repressor/biotin-[acetyl-CoA-carboxylase] synthetase TTHA0225 62 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 55981353 Common - chorismate synthase TTHA1384 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 55981545 Common - NAD-dependent glutamate dehydrogenase TTHA1576 180 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 55980513 Nonpathogen - hypothetical protein TTHA0544 1 None None None 55980382 Common - 3-oxoacyl-[acyl carrier protein] synthase II TTHA0413 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 55981746 Common - hypothetical protein TTHA1777 192 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 55981941 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA TTHA1972 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 55980748 Common - dihydroorotate dehydrogenase 2 TTHA0779 228 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 55981484 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase TTHA1515 204 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 55980978 Common - hypothetical protein TTHA1009 24 COG1309 AcrR, Transcriptional regulator Transcription 55981067 Common - membrane lipoprotein TTHA1098 104 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 55981293 Common - DNA mismatch repair protein TTHA1324 205 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 55980077 Common - transketolase TTHA0108 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 55981613 Common - hypothetical protein TTHA1644 121 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 55980357 Common - bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase TTHA0388 191 COG2876 AroA, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 55981541 Common - hypothetical protein TTHA1572 9 COG1569 COG1569, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 55980991 Common - hypothetical protein TTHA1022 6 None None None 55981081 Nonpathogen - hypothetical protein TTHA1112 2 COG4371 COG4371, Predicted membrane protein Function unknown 55981340 Nonpathogen - hypothetical protein TTHA1371 1 None None None 55981684 Common - hypothetical protein TTHA1715 195 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 55980859 Common - putative 3-hydroxyacyl-CoA dehydrogenase TTHA0890 162 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 55980966 Nonpathogen - hypothetical protein TTHA0997 1 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 55980018 Common - diacylglycerol kinase-related protein TTHA0049 97 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 55980041 Common - hypothetical protein TTHA0072 38 COG2720 COG2720, Uncharacterized vancomycin resistance protein Defense mechanisms 55981378 Common - cytochrome c-type biogenesis protein CcdA TTHA1409 57 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 55981839 Nonpathogen - hypothetical protein TTHA1870 1 None None None 55980715 Common - iron ABC transporter, substrate-binding protein TTHA0746 160 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 55981479 Common - hypothetical protein TTHA1510 12 COG2353 COG2353, Uncharacterized conserved protein Function unknown 55980734 Common - probable hydrolase TTHA0765 50 COG3191 DmpA, L-aminopeptidase/D-esterase Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 55980438 Common - peptide ABC transporter, periplasmic peptide-binding protein TTHA0469 207 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 55980946 Common - sugar ABC transporter, permease protein TTHA0977 141 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 55981419 Common - hypothetical protein TTHA1450 10 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 55981468 Common - MoxR-related protein TTHA1499 172 COG0714 COG0714, MoxR-like ATPases General function prediction only 55980274 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase TTHA0305 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 55980006 Nonpathogen - hypothetical protein TTHA0037 1 None None None 55980376 Common - 3-methyl-2-oxobutanoate hydroxymethyltransferase TTHA0407 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 55981524 Common - hypothetical protein TTHA1555 26 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 55980465 Nonpathogen - hypothetical protein TTHA0496 2 None None None 55980183 Common - probable kinase TTHA0214 50 COG1461 COG1461, Predicted kinase related to dihydroxyacetone kinase General function prediction only 55980468 Nonpathogen - putative nucleotidyltransferase protein TTHA0499 4 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 55980646 Common - putative oxidoreductase TTHA0677 13 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 55981155 Common - deoxyribose-phosphate aldolase TTHA1186 107 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 55980992 Nonpathogen - hypothetical protein TTHA1023 1 None None None 55980048 Nonpathogen - hypothetical protein TTHA0079 1 None None None 55981692 Common - sensor histidine kinase TTHA1723 223 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 55981502 Common - hypothetical protein TTHA1533 8 None None None 55981779 Nonpathogen - hypothetical protein TTHA1810 1 None None None 55981699 Nonpathogen - hypothetical protein TTHA1730 1 COG3462 COG3462, Predicted membrane protein Function unknown 55981427 Common - hypothetical protein TTHA1458 18 COG1470 COG1470, Predicted membrane protein Function unknown 55980930 Common - hypothetical protein TTHA0961 96 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 55979983 Nonpathogen - hypothetical protein TTHA0014 1 None None None 55981865 Common - glucosamine--fructose-6-phosphate aminotransferase [isomerizing] TTHA1896 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 55980298 Common - DNA-3-methyladenine glycosidase TTHA0329 61 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 55981936 Common - competence protein ComEA-related protein TTHA1967 57 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 55981878 Nonpathogen - hypothetical protein TTHA1909 1 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 55980506 Common - succinyl-CoA synthetase alpha chain TTHA0537 211 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 55981026 Common - hypothetical protein TTHA1057 64 COG1432 COG1432, Uncharacterized conserved protein Function unknown 55980201 Common - branched-chain alpha-keto acid dehydrogenase subunit E2 TTHA0232 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 55981391 Common - thioredoxin TTHA1422 31 COG2143 COG2143, Thioredoxin-related protein Posttranslational modification, protein turnover, chaperones 55980060 Common - NADH-quinone oxidoreductase chain 8 TTHA0091 180 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 55981741 Common - hypothetical protein TTHA1772 15 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 55981900 Common - quinol-cytochrome c reductase, Rieske iron-sulfur subunit TTHA1931 25 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 55981418 Common - putative hydrolase, TatD family TTHA1449 235 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 55981147 Nonpathogen - hypothetical protein TTHA1178 1 None None None 55980315 Common - peptidyl-prolyl cis-trans isomerase TTHA0346 101 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 55981570 Nonpathogen - hypothetical protein TTHA1601 1 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 55981770 Nonpathogen - hypothetical protein TTHA1801 1 None None None 55980564 Common - galactokinase TTHA0595 82 COG0153 GalK, Galactokinase Carbohydrate transport and metabolism 55981928 Common - phenylalanyl-tRNA synthetase beta chain TTHA1959 211 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 55980750 Common pyrC dihydroorotase TTHA0781 212 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 55981555 Common - DNA gyrase, subunit B TTHA1586 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 55981473 Common - hypothetical protein TTHA1504 15 COG3877 COG3877, Uncharacterized protein conserved in bacteria Function unknown 55980889 Nonpathogen - hypothetical protein TTHA0920 1 None None None 55981788 Common - 2'-5' RNA ligase TTHA1819 74 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 55980054 Common - NADH-quinone oxidoreductase chain 6 TTHA0085 191 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 55980822 Nonpathogen - hypothetical protein TTHA0853 1 None None None 55981584 Common - hypothetical protein TTHA1615 77 COG1259 COG1259, Uncharacterized conserved protein Function unknown 55980281 Common - cytochrome caa3 oxidase subunit I (polypeptide I + III) TTHA0312 175 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 55980575 Common - aspartate alpha-decarboxylase TTHA0606 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 55981579 Common - hypothetical protein TTHA1610 16 COG2331 COG2331, Uncharacterized protein conserved in bacteria Function unknown 55980555 Common - putative long-chain-fatty-acid--CoA ligase TTHA0586 204 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 55980760 Common - hypothetical protein TTHA0791 15 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 55980901 Nonpathogen - hypothetical protein TTHA0932 4 COG1724 COG1724, Predicted periplasmic or secreted lipoprotein Cell motility and secretion 55980388 Nonpathogen - hypothetical protein TTHA0419 10 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 55981031 Common - GTP cyclohydrolase II/3,4-dihydroxy-2-butanone-4-phosphate synthase TTHA1062 232 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 55980519 Common - enoyl-CoA hydratase/isomerase TTHA0550 177 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 55980372 Common - cell division protein FtsH TTHA0403 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 55980232 Common - multidrug-efflux transporter TTHA0263 74 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 55980203 Common - transposase TTHA0234 82 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 55981349 Nonpathogen - competence protein PilN TTHA1380 2 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 55981690 Nonpathogen - hypothetical protein TTHA1721 4 COG3462 COG3462, Predicted membrane protein Function unknown 55981395 Nonpathogen - hypothetical protein TTHA1426 1 None None None 55981768 Common - hypothetical protein TTHA1799 100 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 55980682 Nonpathogen - hypothetical protein TTHA0713 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 55980306 Nonpathogen - hypothetical protein TTHA0337 1 None None None 55979997 Nonpathogen - putative macrolide-efflux protein TTHA0028 9 None None None 55981066 Common - DNA ligase [NAD+] TTHA1097 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 55981231 Common - 3-hydroxybutyryl-CoA dehydrogenase TTHA1262 161 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 55980757 Nonpathogen - DNA polymerase III, delta subunit TTHA0788 2 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 55980378 Common - putative modification methylase TTHA0409 133 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 55981624 Common - octaprenyl-diphosphate synthase TTHA1655 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 55980561 Nonpathogen - hypothetical protein TTHA0592 1 None None None 55980639 Common - shiroheme synthase (precorrin-2 oxidase/ferrochelatase) TTHA0670 142 COG1648 CysG, Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) Coenzyme metabolism 55980251 Common - acetyltransferase TTHA0282 105 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 55981110 Common - cation-transporting ATPase TTHA1141 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 55981763 Common mgsA methylglyoxal synthase TTHA1794 88 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 55980240 Common groEL chaperonin GroEL TTHA0271 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 55980166 Nonpathogen - S-layer-like protein TTHA0197 2 None None None 55980939 Common - phenylacetic acid degradation protein PaaC TTHA0970 45 COG3396 COG3396, Uncharacterized conserved protein Function unknown 55981122 Common - mercuric reductase TTHA1153 241 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 55980247 Common - phosphoenolpyruvate carboxykinase TTHA0278 98 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 55979989 Common - response regulator TTHA0020 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 55980609 Common - hypothetical protein TTHA0640 16 COG2250 COG2250, Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN Function unknown 55980684 Common - ABC transporter ATP-binding protein TTHA0715 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 55981640 Common - adenylate kinase TTHA1671 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 55980737 Common - putative large integral membrane transport protein TTHA0768 123 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 55981598 Common - iron ABC transporter, permease protein TTHA1629 177 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 55981782 Common rpoB DNA-directed RNA polymerase subunit beta TTHA1813 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 55981744 Common - pantoate--beta-alanine ligase TTHA1775 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 55981854 Nonpathogen - hypothetical protein TTHA1885 1 None None None 55980499 Nonpathogen - hypothetical protein TTHA0530 4 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 55980128 Nonpathogen - hypothetical protein TTHA0159 1 None None None 55981327 Nonpathogen - hypothetical protein TTHA1358 1 None None None 55980801 Common - hypothetical protein TTHA0832 19 None None None 55980058 Common - NADH-quinone oxidoreductase chain 1 TTHA0089 169 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 55981028 Common - ADP-ribosylglycohydrolase TTHA1059 61 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 55980982 Nonpathogen - hypothetical protein TTHA1013 1 None None None 55981090 Common - N-utilization substance protein B TTHA1121 109 COG0781 NusB, Transcription termination factor Transcription 55981204 Nonpathogen - cytochrome c-552 precursor (C552) TTHA1235 1 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 55981298 Common - glutamine synthetase TTHA1329 231 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 55980149 Common - DNA polymerase III alpha subunit TTHA0180 222 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 55981674 Common - probable esterase TTHA1705 30 COG1647 COG1647, Esterase/lipase General function prediction only 55981648 Common rpsN 30S ribosomal protein S14 TTHA1679 155 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 55980749 Nonpathogen - hypothetical protein TTHA0780 2 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 55981318 Common - DNA-binding protein HU (DNA-binding protein II) TTHA1349 212 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 55980036 Common - L-asparaginase II TTHA0067 46 COG4448 AnsA, L-asparaginase II Amino acid transport and metabolism 55980617 Common - probable glycosyltransferase TTHA0648 218 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 55981517 Common - excinuclease ABC subunit C (UvrC) TTHA1548 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 55981634 Common rpsD 30S ribosomal protein S4 TTHA1665 245 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 55980692 Common - iron(III) ABC transporter, solute-binding protein TTHA0723 125 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 55980115 Common - alanyl-tRNA synthetase-related protein TTHA0146 198 COG2872 COG2872, Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain General function prediction only 55981688 Common - copper homeostasis operon regulatory protein TTHA1719 75 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 55981847 Common folE GTP cyclohydrolase I TTHA1878 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 55981191 Nonpathogen - pilin, type IV, putative TTHA1222 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 55981735 Common - S-layer-like protein TTHA1766 22 COG5479 COG5479, Uncharacterized protein potentially involved in peptidoglycan biosynthesis Cell envelope biogenesis, outer membrane 55981153 Nonpathogen - putative response regulator TTHA1184 2 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 55981568 Common - hypothetical protein TTHA1599 27 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 55980623 Common - ATP-binding protein, Mrp/Nbp35 family TTHA0654 234 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 55981636 Common rpsM 30S ribosomal protein S13 TTHA1667 246 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 55981907 Common - acyl-CoA dehydrogenase TTHA1938 167 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 55981380 Common - sulfite dehydrogenase SoxC precursor TTHA1411 98 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 55981136 Common - single-stranded DNA specific exonuclease RecJ TTHA1167 198 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 55980267 Nonpathogen - hypothetical protein TTHA0298 2 None None None 55981874 Nonpathogen - hypothetical protein TTHA1905 17 COG2250 COG2250, Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN Function unknown 55981911 Common - putative cytochrome c oxidase assembly protein TTHA1942 103 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 55981681 Nonpathogen - hypothetical protein TTHA1712 3 None None None 55980826 Common - phosphatidate cytidylyltransferase TTHA0857 214 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 55980807 Common - glutaredoxin-like protein TTHA0838 88 COG3634 AhpF, Alkyl hydroperoxide reductase, large subunit Posttranslational modification, protein turnover, chaperones 55980491 Common - hypothetical protein TTHA0522 16 COG0433 COG0433, Predicted ATPase General function prediction only 55980742 Nonpathogen - hypothetical protein TTHA0773 1 None None None 55980732 Common - zinc-dependent dehydrogenase TTHA0763 114 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 55980011 Common rpmB 50S ribosomal protein L28 TTHA0042 4 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 55980405 Common - signal recognition particle-docking protein FtsY TTHA0436 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 55981894 Nonpathogen - hypothetical protein TTHA1925 1 None None None 55980913 Nonpathogen - hypothetical protein TTHA0944 1 None None None 55980334 Common - type IV pilus assembly protein, pilus retraction protein PilT TTHA0365 183 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 55980903 Common - glutamate-1-semialdehyde 2,1-aminomutase (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-AT) TTHA0934 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 55981366 Common rpsT 30S ribosomal protein S20 TTHA1397 164 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 55981266 Nonpathogen - hypothetical protein TTHA1297 1 None None None 55980260 Common - Holliday junction DNA helicase RuvA TTHA0291 183 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 55981107 Common rpsO 30S ribosomal protein S15 TTHA1138 214 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 55980754 Common - hypothetical protein TTHA0785 13 COG0730 COG0730, Predicted permeases General function prediction only 55980865 Common - Zn-dependent protease TTHA0896 39 COG2738 COG2738, Predicted Zn-dependent protease General function prediction only 55981455 Nonpathogen - hypothetical protein TTHA1486 1 None None None 55980814 Common - probable transcriptional regulator, AsnC family TTHA0845 42 COG1522 Lrp, Transcriptional regulators Transcription 55980227 Common - probable tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase TTHA0258 214 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 55981286 Common - immunogenic protein related protein TTHA1317 72 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 55981889 Common - thioredoxin reductase TTHA1920 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 55980773 Common - radical SAM domain protein TTHA0804 81 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 55981439 Common - replicative DNA helicase DnaB TTHA1470 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 55980463 Nonpathogen - hypothetical protein TTHA0494 1 None None None 55981535 Common - hypothetical protein TTHA1566 20 COG4365 COG4365, Uncharacterized protein conserved in bacteria Function unknown 55981304 Common - branched-chain amino acid ABC transporter, ATP-binding protein TTHA1335 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 55981886 Common - 3-octaprenyl-4-hydroxybenzoate carboxy-lyase TTHA1917 151 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 55980834 Common - NAD-dependent aldehyde dehydrogenase TTHA0865 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 55980199 Common - 2-oxoisovalerate dehydrogenase, E1 component beta subunit TTHA0230 192 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 55981704 Common - iron-sulfur cluster biosynthesis protein IscS (cysteine desulfurase) TTHA1735 238 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 55981006 Common - hypothetical protein TTHA1037 27 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 55981772 Common - pterin-4-alpha-carbinolamine dehydratase TTHA1803 117 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 55981752 Common rplU 50S ribosomal protein L21 TTHA1783 215 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 55980662 Common - 3-hydroxybutyrate dehydrogenase TTHA0693 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 55980706 Common - putative dihidrodipicolinate synthase TTHA0737 222 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 55981821 Common - oligoendopeptidase F TTHA1852 87 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 55980604 Common - probable nucleotidyltransferase TTHA0635 9 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 55980840 Nonpathogen - hypothetical protein TTHA0871 1 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 55981036 Common ileS isoleucyl-tRNA synthetase TTHA1067 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 55980425 Common - cysteine desulfurase/cysteine sulfinate desulfinase TTHA0456 234 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 55980505 Common - malate dehydrogenase TTHA0536 159 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 55980422 Common - Mn2+/Zn2+ ABC transporter, ATP-binding protein TTHA0453 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 55981805 Common - isocitrate lyase TTHA1836 128 COG2224 AceA, Isocitrate lyase Energy production and conversion 55980672 Common - cell wall endopeptidase, family M23/M37 TTHA0703 195 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 55980679 Common - phenazine biosynthesis protein related protein TTHA0710 105 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 55981505 Common - putative oxidoreductase-like protein TTHA1536 70 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 55981438 Common - hypothetical protein TTHA1469 26 None None None 55980347 Common - sugar ABC transporter, permease protein TTHA0378 143 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 55980487 Common - TerC family protein TTHA0518 125 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 55980075 Common - ribulose-phosphate 3-epimerase TTHA0106 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 55981525 Common - ribonuclease H (RNase H) TTHA1556 175 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 55980293 Common - phosphopentomutase TTHA0324 70 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 55981017 Common - hypothetical protein TTHA1048 18 COG4864 COG4864, Uncharacterized protein conserved in bacteria Function unknown 55980589 Common - alternative anthranilate synthase component I+II (TrpEG) TTHA0620 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 55981617 Nonpathogen - hypothetical protein TTHA1648 4 COG2361 COG2361, Uncharacterized conserved protein Function unknown 55981184 Common - probable thioredoxin reductase TTHA1215 218 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 55981269 Common - bacterioferritin comigratory protein, thiol peroxidase, putative TTHA1300 231 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 55980212 Common rpsR 30S ribosomal protein S18 TTHA0243 212 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 55980192 Common - hypothetical protein TTHA0223 124 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 55980022 Common - hypothetical protein TTHA0053 9 COG2129 COG2129, Predicted phosphoesterases, related to the Icc protein General function prediction only 55981407 Nonpathogen - hypothetical protein TTHA1438 16 COG2045 COG2045, Phosphosulfolactate phosphohydrolase and related enzymes Coenzyme metabolism / General function prediction only 55980546 Nonpathogen - hypothetical protein TTHA0577 4 None None None 55980442 Common - peptide ABC transporter, ATP-binding protein TTHA0473 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 55981173 Common - hypothetical protein TTHA1204 22 COG3694 COG3694, ABC-type uncharacterized transport system, permease component General function prediction only 55980472 Common - glycolate oxidase iron-sulfur subunit GlcF TTHA0503 178 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 55980596 Common - large-conductance mechanosensitive channel TTHA0627 142 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 55980847 Common - hypothetical protein TTHA0878 80 COG4121 COG4121, Uncharacterized conserved protein Function unknown 55981652 Common rpsQ 30S ribosomal protein S17 TTHA1683 230 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 55980656 Nonpathogen - sugar ABC transporter, permease protein [N-terminal] TTHA0687 10 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 55981934 Common - inorganic pyrophosphatase TTHA1965 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 55981228 Common - adenylate cyclase related protein TTHA1259 41 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 55980311 Common - probable N-succinyldiaminopimelate aminotransferase TTHA0342 235 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 55980524 Common - hypothetical protein TTHA0555 20 COG5322 COG5322, Predicted dehydrogenase General function prediction only 55981902 Common - probable c-type cytochrome TTHA1933 64 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 55981166 Common argC N-acetyl-gamma-glutamyl-phosphate reductase TTHA1197 215 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 55981382 Nonpathogen - hypothetical protein TTHA1413 1 COG3439 COG3439, Uncharacterized conserved protein Function unknown 55980893 Nonpathogen - hypothetical protein TTHA0924 6 COG1355 COG1355, Predicted dioxygenase General function prediction only 55980301 Nonpathogen - hypothetical protein TTHA0332 1 None None None 55981581 Common - putative hydrolase TTHA1612 10 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 55980664 Common - amino acid ABC transporter ATP-binding protein [C-terminal] TTHA0695 245 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 55981213 Common - hypothetical protein TTHA1244 112 COG1733 COG1733, Predicted transcriptional regulators Transcription 55981218 Common - acetyl-coenzyme A synthetase TTHA1249 205 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 55981425 Common - succinate dehydrogenase, cytochrome subunit TTHA1456 23 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 55981538 Nonpathogen - hypothetical protein TTHA1569 1 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 55980584 Common - ATP-dependent Clp protease, proteolytic subunit ClpP TTHA0615 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 55980836 Nonpathogen - hypothetical protein TTHA0867 1 None None None 55980485 Common - hypothetical protein TTHA0516 13 None None None 55980067 Common argS arginyl-tRNA synthetase TTHA0098 248 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 55980783 Common - putative response regulator TTHA0814 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 55981178 Common - probable acetyltransferase TTHA1209 72 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 55981710 Nonpathogen - hypothetical protein TTHA1741 1 None None None 55981543 Common - putative dehydrogenase TTHA1574 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 55981482 Common - adenylosuccinate lyase TTHA1513 237 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 55980794 Common - S-adenosylmethionine decarboxylase proenzyme TTHA0825 25 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 55981471 Common - response regulator TTHA1502 226 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 55980359 Common - hypothetical protein TTHA0390 28 COG3573 COG3573, Predicted oxidoreductase General function prediction only 55980073 Nonpathogen - hypothetical protein TTHA0104 3 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 55981547 Common - 1-pyrroline-5-carboxylate dehydrogenase TTHA1578 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 55981054 Common - UDP-N-acetylmuramate--alanine ligase TTHA1085 207 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 55981489 Common - amidophosphoribosyltransferase TTHA1520 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 55981497 Nonpathogen - hypothetical protein TTHA1528 2 None None None 55981201 Common - hypothetical protein TTHA1232 22 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 55980321 Common - peptidyl-prolyl cis-trans isomerse, PpiC family TTHA0352 11 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 55980214 Common rpsF 30S ribosomal protein S6 TTHA0245 108 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 55980084 Common - prolyl-tRNA synthetase TTHA0115 207 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 55981603 Common - peptide ABC transporter, peptide-binding protein TTHA1634 177 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 55980453 Common - apolipoprotein N-acyltransferase TTHA0484 163 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 55980288 Common - hypothetical protein TTHA0319 139 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 55980093 Common - branched-chain amino acid aminotransferase (IlvE) TTHA0124 213 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 55981892 Common - sodium ABC transporter, permease protein NatB TTHA1923 5 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 55980150 Nonpathogen - hypothetical protein TTHA0181 1 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 55981921 Common - DNA polymerase III holoenzyme tau subunit TTHA1952 244 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 55980159 Common - dihydroneopterin aldolase TTHA0190 31 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 55980971 Common - response regulator TTHA1002 212 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 55981844 Common - threonyl-tRNA synthetase TTHA1875 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 55981586 Common - probable HIT family protein TTHA1617 235 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 55980905 Nonpathogen - CBS domain protein TTHA0936 3 COG0517 COG0517, FOG: CBS domain General function prediction only 55981010 Common - lysyl-tRNA synthetase (lysine--tRNA ligase) (LysRS) TTHA1041 237 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 55980130 Common - leucyl-tRNA synthetase TTHA0161 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 55980418 Common - branched-chain amino acid ABC transporter, permease protein TTHA0449 129 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 55981256 Nonpathogen - hypothetical protein TTHA1287 4 None None None 55981793 Common - chloromuconate cycloisomerase TTHA1824 57 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 55981284 Common - putative integral membrane efflux protein TTHA1315 143 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 55980366 Common - hypothetical protein TTHA0397 26 COG0795 COG0795, Predicted permeases General function prediction only 55981412 Common - hypothetical protein TTHA1443 5 None None None 55980850 Common - glycosyltransferase TTHA0881 216 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 55980139 Common - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase TTHA0170 159 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 55981719 Common - putative mannose-1-phosphate guanylyl transferase (GDP)/mannose-6-phosphate isomerase TTHA1750 162 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 55980541 Common - tRNA delta(2)-isopentenylpyrophosphate transferase TTHA0572 213 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 55981295 Common - cytochrome c-552 like protein TTHA1326 32 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 55981487 Common - 2-haloalkanoic acid dehalogenase-related protein TTHA1518 49 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 55980752 Common - pyrimidine regulatory protein PyrR TTHA0783 111 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 55981240 Common - V-type ATP synthase subunit D TTHA1271 43 COG1394 NtpD, Archaeal/vacuolar-type H+-ATPase subunit D Energy production and conversion 55980122 Common - NADPH:quinone reductase TTHA0153 178 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 55980397 Common - histidinol-phosphate aminotransferase TTHA0428 220 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 55981629 Common - hypothetical protein TTHA1660 100 COG1403 McrA, Restriction endonuclease Defense mechanisms 55980898 Common - phosphopantetheine adenylyltransferase TTHA0929 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 55980119 Common - hypothetical protein TTHA0150 4 None None None 55980296 Common - 5,10-methylenetetrahydrofolate reductase TTHA0327 149 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 55981376 Nonpathogen - cytochrome c-type biogenesis protein, heme exporter protein B TTHA1407 8 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 55980350 Nonpathogen - hypothetical protein TTHA0381 1 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 55981335 Common - putative iron-sulfur protein TTHA1366 94 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 55980100 Common - hypothetical protein TTHA0131 14 None None None 55981480 Common - putative catechol 1,2-dioxygenase TTHA1511 34 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 55980887 Nonpathogen - hypothetical protein TTHA0918 1 None None None 55981572 Nonpathogen - hypothetical protein TTHA1603 1 None None None 55980175 Common - nicotinamide nucleotide transhydrogenase, alpha subunit 1 TTHA0206 165 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 55981355 Common - 3-dehydroquinate synthase TTHA1386 204 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 55980984 Common - probable nucleotidyltransferase TTHA1015 55 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 55980944 Common - sugar ABC transporter, ATP-binding protein TTHA0975 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 55981683 Common - putative heme peroxidase TTHA1714 30 COG3253 COG3253, Uncharacterized conserved protein Function unknown 55979995 Common - hypothetical protein TTHA0026 16 COG3369 COG3369, Uncharacterized conserved protein Function unknown 55980185 Common - alanine dehydrogenase TTHA0216 167 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 55980573 Common - medium-chain-fatty-acid--CoA ligase TTHA0604 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 55981897 Common - gamma-glutamyl phosphate reductase TTHA1928 187 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 55981238 Common - transposase TTHA1269 82 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 55981099 Common - ArgE/DapE/Acy1 family peptidase TTHA1130 157 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 55980595 Common - phosphoenolpyruvate carboxylase TTHA0626 117 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 55981142 Common - Trk system potassium uptake protein (TrkG) TTHA1173 119 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 55981596 Common - hypothetical protein TTHA1627 12 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 55980821 Common - pyrroline-5-carboxylate reductase TTHA0852 212 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 55981679 Common - radical SAM domain protein TTHA1710 90 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 55980998 Common - L-serine dehydratase, alpha subunit TTHA1029 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 55979976 Nonpathogen - hypothetical protein TTHA0007 2 None None None 55981083 Common - ferric enterobactin esterase-related protein TTHA1114 24 COG2382 Fes, Enterochelin esterase and related enzymes Inorganic ion transport and metabolism 55980046 Common - inositol monophophatase family protein TTHA0077 196 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 55981918 Common - hypothetical protein TTHA1949 20 COG3391 COG3391, Uncharacterized conserved protein Function unknown 55981075 Nonpathogen - hypothetical protein TTHA1106 2 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 55981198 Common - 3-isopropylmalate dehydratase small subunit TTHA1229 209 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 55981522 Common - hypothetical protein TTHA1553 27 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 55981247 Common - V-type ATP synthase subunit I TTHA1278 38 COG1269 NtpI, Archaeal/vacuolar-type H+-ATPase subunit I Energy production and conversion 55981837 Common - extracellular serine protease TTHA1868 115 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 55981447 Nonpathogen - hypothetical protein TTHA1478 1 COG3431 COG3431, Predicted membrane protein Function unknown 55980765 Nonpathogen - hypothetical protein TTHA0796 1 None None None 55981313 Common - molybdopterin biosynthesis protein MoeB TTHA1344 213 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 55981651 Common rplN 50S ribosomal protein L14 TTHA1682 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 55981044 Common - hypothetical protein TTHA1075 128 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 55980854 Common - rhamnosyl transferase TTHA0885 86 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 55979987 Common - glycogen synthase (Starch [bacterial glycogen] synthase) TTHA0018 180 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 55980642 Nonpathogen - hypothetical protein TTHA0673 1 None None None 55980423 Common - Mn2+/Zn2+ ABC transporter, permease protein TTHA0454 68 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 55980631 Common - hypothetical protein TTHA0662 7 None None None 55981092 Common - acetyl-CoA carboxylase, biotin carboxylase subunit TTHA1123 235 COG0439 AccC, Biotin carboxylase Lipid metabolism 55981864 Nonpathogen - hypothetical protein TTHA1895 1 None None None 55980557 Common - branched-chain amino acid ABC transport ATP-binding protein TTHA0588 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 55981037 Common - proline dipeptidase TTHA1068 248 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 55980373 Nonpathogen - hypothetical protein TTHA0404 2 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 55979974 Common - metallo-beta-lactamase family protein TTHA0005 11 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 55981453 Common - small heat shock protein, HSP20 family TTHA1484 93 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 55980428 Nonpathogen - hypothetical protein TTHA0459 2 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 55980419 Common - branched-chain amino acid ABC transporter, permease protein TTHA0450 127 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 55981202 Common - short-chain dehydrogenase/reductase family protein TTHA1233 210 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 55980322 Common - phosphoglucomutase TTHA0353 237 COG0033 Pgm, Phosphoglucomutase Carbohydrate transport and metabolism 55981015 Common - PhoH-related protein TTHA1046 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 55980217 Common - transcription antitermination protein NusG TTHA0248 215 COG0250 NusG, Transcription antiterminator Transcription 55980446 Common - probable ATP pyrophosphatase, PP-loop superfamily TTHA0477 147 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 55980658 Common - putative xylose repressor [C-terminal] TTHA0689 63 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 55980767 Common - GGDEF domain protein TTHA0798 176 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 55980666 Common - bifunctional preprotein translocase subunit SecD/SecF TTHA0697 214 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 55981445 Nonpathogen - probable Na(+)/H(+) antiporter TTHA1476 1 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 55981077 Nonpathogen - hypothetical protein TTHA1108 3 COG0795 COG0795, Predicted permeases General function prediction only 55981151 Common - hypothetical protein TTHA1182 156 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 55981117 Common - propionyl-CoA carboxylase, alpha subunit TTHA1148 212 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 55980360 Common - hypothetical protein TTHA0391 27 COG3573 COG3573, Predicted oxidoreductase General function prediction only 55980051 Nonpathogen - probable phosphoesterase TTHA0082 2 None None None 55980278 Common - hypothetical protein TTHA0309 124 COG0628 PerM, Predicted permease General function prediction only 55980361 Common - probable methylmalonyl-CoA epimerase TTHA0392 71 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 55980460 Common - threonine synthase TTHA0491 132 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 55980583 Common - trigger factor TTHA0614 209 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 55980351 Nonpathogen - hypothetical protein TTHA0382 2 COG2839 COG2839, Uncharacterized protein conserved in bacteria Function unknown 55981024 Common - hypothetical protein TTHA1055 45 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 55981261 Common - metal uptake regulation protein, putative TTHA1292 141 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 55980709 Nonpathogen - sensor histidine kinase TTHA0740 1 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 55981807 Common - SufC protein (ATP-binding protein) TTHA1838 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 55979999 Nonpathogen - hypothetical protein TTHA0030 2 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 55981306 Common - peptide ABC transporter, permease protein TTHA1337 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 55981504 Common - isocitrate dehydrogenase TTHA1535 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 55981275 Nonpathogen - hypothetical protein TTHA1306 2 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 55980344 Nonpathogen - putative glycoprotein endopeptidase TTHA0375 1 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 55980988 Common - hypothetical protein TTHA1019 9 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 55980673 Common - pyridoxine biosynthesis protein TTHA0704 87 COG0214 SNZ1, Pyridoxine biosynthesis enzyme Coenzyme metabolism 55980013 Common - putative Na(+)/H(+) antiporter TTHA0044 43 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 55981363 Common - homoserine kinase TTHA1394 117 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 55981001 Common - tRNA (guanine-N1)-methyltransferase TTHA1032 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 55980123 Nonpathogen - hypothetical protein TTHA0154 1 None None None 55981828 Common - PSP1-related protein TTHA1859 58 COG1774 COG1774, Uncharacterized homolog of PSP1 Function unknown 55981567 Common - delta-aminolevulinic acid dehydratase TTHA1598 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 55981159 Nonpathogen - rod shape-determining protein MreD TTHA1190 1 None None None 55980083 Common - ABC transporter ATP-binding protein TTHA0114 221 COG2401 COG2401, ABC-type ATPase fused to a predicted acetyltransferase domain General function prediction only 55981291 Common - ribonuclease activity regulator protein RraA TTHA1322 81 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 55980686 Common - molybdenum ABC transporter molybdate-binding protein TTHA0717 137 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 55980816 Common - putative phosphohydrolase TTHA0847 15 COG1768 COG1768, Predicted phosphohydrolase General function prediction only 55980536 Common - acylphosphatase TTHA0567 147 COG1254 AcyP, Acylphosphatases Energy production and conversion 55981687 Common - heavy metal binding protein TTHA1718 110 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 55980729 Common - O-acetyl-L-homoserine sulfhydrylase TTHA0760 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 55980302 Common - hypothetical protein TTHA0333 100 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 55980102 Common - oxidoreductase, short-chain dehydrogenase/reductase family TTHA0133 193 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 55980693 Common - serine protease TTHA0724 140 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 55980229 Common - probable phosphate ABC transporter, permease protein TTHA0260 224 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 55981472 Common - sensor histidine kinase TTHA1503 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 55981534 Common - sporulation protein SpoIID-related protein TTHA1565 48 COG2385 SpoIID, Sporulation protein and related proteins Cell division and chromosome partitioning 55980937 Common - bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase TTHA0968 215 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 55981750 Common obgE GTPase ObgE TTHA1781 249 COG0536 Obg, Predicted GTPase General function prediction only 55981815 Common - putative thioesterase TTHA1846 53 COG0824 FcbC, Predicted thioesterase General function prediction only 55981013 Nonpathogen - diacylglycerol kinase TTHA1044 1 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 55980329 Common - survival protein SurE TTHA0360 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 55981061 Common - conserved hypothetical protein (radical SAM superfamily) TTHA1092 83 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 55980704 Common - cytidine deaminase TTHA0735 112 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 55980779 Common - metallo-beta-lactamase related protein TTHA0810 105 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 55980034 Nonpathogen - glycolate oxidase subunit GlcE TTHA0065 2 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 55981641 Common secY preprotein translocase subunit SecY TTHA1672 244 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 55981649 Common rplE 50S ribosomal protein L5 TTHA1680 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 55980137 Common - hypothetical protein TTHA0168 76 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 55981325 Common - divalent cation tolerance protein (Cut A1) TTHA1356 120 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 55981084 Common - integral membrane protein TerC family TTHA1115 41 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 55980004 Nonpathogen - hypothetical membrane protein TTHA0035 1 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 55980493 Common - glycine cleavage system H protein TTHA0524 183 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 55981102 Nonpathogen - ba3-type cytochrome c oxidase polypeptide IIA TTHA1133 1 None None None 55981597 Common - iron ABC transporter, periplasmic iron-binding protein TTHA1628 109 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 55981301 Common - branched-chain amino acid ABC transporter, permease protein TTHA1332 154 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 55981845 Common - probable repressor, phenylacetic acid catabolic pathway TTHA1876 27 COG3327 PaaX, Phenylacetic acid-responsive transcriptional repressor Transcription 55981910 Common - ZIP zinc transporter family protein TTHA1941 66 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 55981141 Common - alpha-glucan phosphorylase TTHA1172 146 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 55980268 Common - glucokinase TTHA0299 14 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 55981064 Common - tryptophan synthase subunit beta TTHA1095 227 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 55980337 Common - phosphoglycerate mutase TTHA0368 187 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 55980386 Common - 3-oxoacyl-[acyl carrier protein] synthase III TTHA0417 224 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 55980980 Nonpathogen - hypothetical protein TTHA1011 1 None None None 55981695 Common - S-layer repressor TTHA1726 9 None None None 55980860 Common - acetyl-CoA acetyltransferase TTHA0891 187 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 55981171 Common - hypothetical protein TTHA1202 44 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 55980241 Common groES co-chaperonin GroES TTHA0272 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 55981182 Common - acetolactate synthase, large subunit TTHA1213 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 55981794 Nonpathogen - hypothetical protein TTHA1825 2 None None None 55980020 Nonpathogen - hypothetical protein TTHA0051 3 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 55981337 Common - signal peptidase I TTHA1368 129 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 55981254 Common - acetyl-coenzyme A synthetase TTHA1285 212 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 55981852 Nonpathogen - hypothetical protein TTHA1883 1 None None None 55981909 Common prfA peptide chain release factor 1 TTHA1940 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 55981078 Common - putative glycosyltransferase TTHA1109 21 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 55980950 Common - hypothetical protein TTHA0981 148 COG1733 COG1733, Predicted transcriptional regulators Transcription 55980782 Common - DNA polymerase III epsilon chain-like protein TTHA0813 174 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 55980845 Nonpathogen gatC aspartyl/glutamyl-tRNA amidotransferase subunit C TTHA0876 1 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 55981310 Common - ABC transporter, ATP-binding protein TTHA1341 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 55980945 Common - sugar ABC transporter, permease protein TTHA0976 119 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 55981401 Common - hypothetical protein TTHA1432 21 COG5502 COG5502, Uncharacterized conserved protein Function unknown 55979990 Common - putative NADPH oxidoreductase TTHA0021 19 COG0778 NfnB, Nitroreductase Energy production and conversion 55980523 Nonpathogen - small multidrug export protein TTHA0554 6 COG2426 COG2426, Predicted membrane protein Function unknown 55980909 Common - aminotransferase TTHA0940 236 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 55981160 Common - penicillin-binding protein 2/cell division protein FtsI TTHA1191 202 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 55980029 Nonpathogen - hypothetical protein TTHA0060 1 None None None 55980318 Common - CBS domain protein TTHA0349 135 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 55981787 Common recA recombinase A TTHA1818 214 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 55980875 Common pgk phosphoglycerate kinase TTHA0906 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 55980254 Common - hypothetical protein TTHA0285 16 None None None 55980928 Common - 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenaseiheyensis HTE831]' TTHA0959 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 55981631 Common - hypothetical protein TTHA1662 9 None None None 55981612 Common - glutamate racemase TTHA1643 191 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 55980577 Common - probable RNA-biniding protein TTHA0608 80 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 55981677 Nonpathogen - hypothetical protein TTHA1708 2 None None None 55981720 Common - putative glycosyltransferase TTHA1751 134 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 55981583 Common - adenine phosphoribosyltransferase TTHA1614 22 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 55981669 Nonpathogen - hypothetical protein TTHA1700 2 None None None 55981737 Common - acetyl-CoA carboxylase carboxyl transferase, beta subunit (AccD) TTHA1768 207 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 55981664 Common - elongation factor G TTHA1695 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 55981321 Common - response regulator TTHA1352 218 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 55980238 Common - type IV prepilin peptidase (PilD) TTHA0269 122 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 55980108 Nonpathogen - hypothetical protein TTHA0139 2 None None None 55980432 Nonpathogen - hypothetical protein TTHA0463 3 COG3557 COG3557, Uncharacterized domain/protein associated with RNAses G and E Translation, ribosomal structure and biogenesis 55980607 Nonpathogen - hypothetical protein TTHA0638 1 None None None 55981706 Nonpathogen - hypothetical protein TTHA1737 1 None None None 55981167 Common - hypothetical protein TTHA1198 15 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 55980918 Common - D-tyrosyl-tRNA deacylase TTHA0949 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 55981347 Common - homoisocitrate dehydrogenase TTHA1378 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 55980165 Common - transporter, periplasmic component TTHA0196 94 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 55981784 Common - (3R)-hydroxymyristoyl-acyl carrier protein dehydratase TTHA1815 186 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 55981112 Common - sensor histidine kinase TTHA1143 222 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 55980044 Common - ribonucleoside-diphosphate reductase TTHA0075 160 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 55981588 Common - probable methyltransferase TTHA1619 175 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 55981601 Common - peptide ABC transporter, permease protein TTHA1632 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 55981491 Common - probable GTP-binding protein TTHA1522 83 COG1159 Era, GTPase General function prediction only 55980111 Common - peptide chain release factor 2 TTHA0142 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 55981520 Common - S-ribosylhomocysteinase TTHA1551 55 COG1854 LuxS, LuxS protein involved in autoinducer AI2 synthesis Signal transduction mechanisms 55980579 Common - hypothetical protein TTHA0610 57 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 55981506 Common - hypothetical protein TTHA1537 9 None None None 55980586 Common - nicotinate phosphoribosyltransferase TTHA0617 103 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 55981381 Common - sulfide dehydrogenase flavocytochrome C TTHA1412 56 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 55981727 Common - GGDEF domain protein TTHA1758 175 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 55981234 Common - zinc-dependent peptidase TTHA1265 173 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 55981835 Nonpathogen - hypothetical protein TTHA1866 1 None None None 55981627 Nonpathogen - hypothetical protein TTHA1658 1 COG3147 DedD, Uncharacterized protein conserved in bacteria Function unknown 55981461 Common - cell division protein FtsH TTHA1492 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 55981356 Common - probable rRNA methylase TTHA1387 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 55980827 Common - ribosome recycling factor (Rrf) TTHA0858 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 55980205 Common - hypothetical protein TTHA0236 5 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 55980628 Common - hypothetical protein TTHA0659 62 COG0679 COG0679, Predicted permeases General function prediction only 55980830 Common rpsB 30S ribosomal protein S2 TTHA0861 246 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 55980802 Common - hypothetical protein TTHA0833 75 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 55980032 Common - primosomal protein N TTHA0063 196 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 55981246 Nonpathogen - V-type ATP synthase, subunit K TTHA1277 1 None None None 55981282 Common - hypothetical protein TTHA1313 113 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 55981861 Common - excinuclease ABC subunit B TTHA1892 224 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 55980560 Common - UDP-glucose 4-epimerase TTHA0591 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 55981374 Common - cytochrome c-type biogenesis protein CcmE TTHA1405 94 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 55980336 Common - phosphoribosylaminoimidazole synthetase TTHA0367 232 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 55979972 Common - pyruvate kinase TTHA0003 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 55980395 Nonpathogen - hypothetical protein TTHA0426 2 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 55980219 Common rpmG 50S ribosomal protein L33 TTHA0250 116 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 55981022 Common - hypothetical protein TTHA1053 131 COG1739 COG1739, Uncharacterized conserved protein Function unknown 55980763 Common - pilus assembly protein PilC TTHA0794 151 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 55981873 Common argC N-acetyl-gamma-glutamyl-phosphate reductase TTHA1904 204 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 55980711 Nonpathogen - hypothetical protein TTHA0742 1 None None None 55980063 Common - NADH-quinone oxidoreductase chain 11 TTHA0094 118 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 55981712 Common - orotidine 5'-phosphate decarboxylase TTHA1743 75 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 55981004 Common rpsP 30S ribosomal protein S16 TTHA1035 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 55980285 Nonpathogen - hypothetical protein TTHA0316 1 None None None 55980345 Nonpathogen - sugar ABC transporter, permease protein TTHA0376 1 None None None 55981575 Common - hypothetical protein TTHA1606 110 COG0327 COG0327, Uncharacterized conserved protein Function unknown 55980611 Common - putative glycosyltransferase TTHA0642 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 55980455 Common - probable iron-sulfur protein TTHA0486 134 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 55980236 Common - oxygen-insensitive NADPH nitroreductase TTHA0267 57 COG0778 NfnB, Nitroreductase Energy production and conversion 55981074 Nonpathogen - hypothetical protein TTHA1105 1 None None None 55980885 Nonpathogen - hypothetical protein TTHA0916 1 None None None 55980503 Common - aspartokinase (aspartate kinase) [contains: aspartokinase alpha subunit; aspartokinase beta subunit] TTHA0534 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 55981485 Common - hypothetical protein TTHA1516 6 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 55981157 Common - septum formation Maf protein TTHA1188 193 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 55981360 Common engA GTP-binding protein EngA TTHA1391 239 COG1160 COG1160, Predicted GTPases General function prediction only 55980291 Nonpathogen - hypothetical protein TTHA0322 1 COG4856 COG4856, Uncharacterized protein conserved in bacteria Function unknown 55981923 Nonpathogen - hypothetical protein TTHA1954 2 None None None 55981742 Common - fructose-1,6-bisphosphate aldolase TTHA1773 179 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 55981259 Nonpathogen - hypothetical protein TTHA1290 1 COG5438 COG5438, Predicted multitransmembrane protein Function unknown 55980369 Common - zinc-binding dehydrogenase TTHA0400 206 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 55981569 Common - RecR protein TTHA1600 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 55980186 Common - tRNA pseudouridine 55 synthase TTHA0217 216 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 55981765 Common - probable thiamine biosynthesis protein ThiI TTHA1796 93 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 55980091 Common - manganese-containing pseudocatalase TTHA0122 46 COG3546 COG3546, Mn-containing catalase Inorganic ion transport and metabolism 55981129 Nonpathogen - hypothetical protein TTHA1160 1 None None None 55981398 Common - metallo-beta-lactamase family protein TTHA1429 112 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 55981893 Common - sodium ABC transporter, ATP-binding protein NatA TTHA1924 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 55980663 Common - branched-chain amino acid ABC transporter, ATP-binding protein TTHA0694 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 55980964 Common - response regulator TTHA0995 220 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 55981536 Common - transcriptional regulatory protein TTHA1567 83 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 55980925 Common - hypothetical protein TTHA0956 14 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 55981027 Common - S-adenosylmethionine:tRNA ribosyltransferase-isomerase TTHA1058 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 55980867 Common - hypothetical protein TTHA0898 11 COG1694 MazG, Predicted pyrophosphatase General function prediction only 55979980 Common - molybdenum cofactor biosynthesis protein A (MoaA) TTHA0011 207 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 55980772 Common - hypothetical protein TTHA0803 22 COG1427 COG1427, Predicted periplasmic solute-binding protein General function prediction only 55981552 Common - site-specific DNA-methyltransferase (adenine-specific) TthHB8I TTHA1583 36 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 55980744 Common - hypothetical protein TTHA0775 2 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 55981478 Common - putative hydrolase TTHA1509 155 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 55981319 Nonpathogen - hypothetical protein TTHA1350 6 COG3580 COG3580, Uncharacterized protein conserved in bacteria Function unknown 55980856 Common - glycosyltransferase TTHA0887 160 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 55980085 Common - cofactor-independent phosphoglycerate mutase TTHA0116 51 COG3635 COG3635, Predicted phosphoglycerate mutase, AP superfamily Carbohydrate transport and metabolism 55981939 Common - chromosome partitioning ATPase, ParA family TTHA1970 226 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 55980718 Nonpathogen - hypothetical protein TTHA0749 1 None None None 55980072 Common - putative oxidoreductase TTHA0103 128 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 55980528 Common - acetyl coenzyme A acetyltransferase (thiolase) TTHA0559 179 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 55981809 Common - SufD protein (membrane protein) TTHA1840 172 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 55981440 Common - putative transglycosylase TTHA1471 140 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 55981593 Nonpathogen - hypothetical protein TTHA1624 7 COG1579 COG1579, Zn-ribbon protein, possibly nucleic acid-binding General function prediction only 55980441 Common - peptide ABC transporter, ATP-binding protein TTHA0472 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 55980974 Nonpathogen - hypothetical protein TTHA1005 2 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 55980144 Common - cold shock protein TTHA0175 178 COG1278 CspC, Cold shock proteins Transcription 55980324 Common - ABC transporter, permease protein, MalFG family TTHA0355 176 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 55981200 Common - hypothetical protein TTHA1231 18 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 55981424 Common - succinate dehydrogenase, membrane subunit (SdhD) TTHA1455 13 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 55980065 Common - NADH-quinone oxidoreductase chain 13 TTHA0096 205 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 55980738 Common - periplasmic serine protease, HtrA/DegQ/DegS family TTHA0769 199 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 55980190 Common - hypothetical protein TTHA0221 94 COG1738 COG1738, Uncharacterized conserved protein Function unknown 55981161 Common - septum site-determining protein MinC TTHA1192 93 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 55981212 Common - septum site-determining protein MinD TTHA1243 147 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 55981079 Common - hypothetical protein TTHA1110 21 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 55981622 Common - hypothetical protein TTHA1653 13 COG1723 COG1723, Uncharacterized conserved protein Function unknown 55981915 Common - nucleoside triphosphate pyrophosphohydrolase TTHA1946 154 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 55980320 Common - probable efflux protein (fosmidomycin resistance) TTHA0351 66 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 55981904 Common - probable NADPH quinone oxidoreductase TTHA1935 160 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 55981385 Common - probable cytochrome c (SoxX) TTHA1416 14 COG3474 COG3474, Cytochrome c2 Energy production and conversion 55980462 Nonpathogen - hypothetical protein TTHA0493 1 None None None 55980724 Common - gamma-glutamyltranspeptidase (acylase) TTHA0755 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 55981220 Common - preprotein translocase subunit SecA TTHA1251 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 55981365 Nonpathogen - 30S ribosomal protein Thx (S31) TTHA1396 1 None None None 55980434 Common - thioredoxin reductase TTHA0465 247 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 55981403 Common - 3-hydroxybutyryl-CoA dehydratase TTHA1434 179 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 55981315 Nonpathogen - hypothetical protein TTHA1346 4 None None None 55981273 Common - sugar ABC transporter, ATP-binding protein TTHA1304 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 55980810 Common - stage V sporulation protein R (SpoVR) related protein TTHA0841 71 COG2719 SpoVR, Uncharacterized conserved protein Function unknown 55981339 Common - serine/threonine-protein kinase-related protein TTHA1370 150 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 55981308 Nonpathogen - hypothetical protein TTHA1339 6 None None None 55981483 Common - hypothetical protein TTHA1514 12 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 55980381 Common - deoxyguanosinetriphosphate triphosphohydrolase, putative TTHA0412 160 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 55981789 Common - competence/damage-inducible protein CinA TTHA1820 209 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 55981888 Nonpathogen - hypothetical protein TTHA1919 3 None None None 55980653 Common - probable TolQ-type transport protein TTHA0684 96 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 55981881 Nonpathogen - hypothetical protein TTHA1912 1 COG1598 COG1598, Uncharacterized conserved protein Function unknown 55980354 Common - UDP-N-acetylglucosamine pyrophosphorylase TTHA0385 233 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 55980648 Common - putative transport protein TTHA0679 66 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 55981757 Nonpathogen - hypothetical protein TTHA1788 2 COG1433 COG1433, Uncharacterized conserved protein Function unknown 55981035 Common - putative translaldolase TTHA1066 188 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 55980500 Nonpathogen - hypothetical protein TTHA0531 3 COG2510 COG2510, Predicted membrane protein Function unknown 55981725 Nonpathogen - hypothetical protein TTHA1756 1 COG1598 COG1598, Uncharacterized conserved protein Function unknown 55980695 Common - aconitate hydratase TTHA0726 223 COG1048 AcnA, Aconitase A Energy production and conversion 55980408 Common - ABC transporter, ATP-binding protein TTHA0439 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 55980263 Common - hypothetical protein TTHA0294 50 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 55981565 Nonpathogen - hypothetical protein TTHA1596 2 None None None 55981532 Common - (neo)pullulanase TTHA1563 162 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 55981813 Common - anthranilate synthase component I (TrpE) TTHA1844 223 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 55981859 Common - aminopeptidase TTHA1890 64 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 55980531 Common - purine nucleoside phosphorylase TTHA0562 101 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 55980671 Common - hypothetical protein TTHA0702 111 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 55981459 Common - GrpE protein (HSP-70 cofactor) TTHA1490 192 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 55980777 Common - hypothetical protein TTHA0808 104 COG0344 COG0344, Predicted membrane protein Function unknown 55980916 Common - triosephosphate isomerase TTHA0947 216 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 55980116 Nonpathogen - hypothetical protein TTHA0147 1 None None None 55981435 Common - CTP synthetase TTHA1466 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 55981600 Common truA tRNA pseudouridine synthase A TTHA1631 232 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 55980538 Common tdh L-threonine 3-dehydrogenase TTHA0569 208 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 55981242 Common - V-type ATP synthase subunit A TTHA1273 247 COG1155 NtpA, Archaeal/vacuolar-type H+-ATPase subunit A Energy production and conversion 55981249 Common - hypothetical protein TTHA1280 124 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 55980638 Common - phosphoadenosine phosphosulfate reductase (CysH) TTHA0669 171 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 55980853 Nonpathogen - probable transposase TTHA0884 8 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 55981932 Common - tetrapyrrole methylase family protein TTHA1963 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 55981780 Common - fuculose-1-phosphate aldolase TTHA1811 115 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 55980470 Common - hypothetical protein TTHA0501 17 COG3742 COG3742, Uncharacterized protein conserved in bacteria Function unknown 55981595 Nonpathogen - hypothetical protein TTHA1626 1 COG3374 COG3374, Predicted membrane protein Function unknown 55980417 Common - long-chain-fatty-acid--CoA ligase TTHA0448 210 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 55981653 Nonpathogen - 30S ribosomal protein L29 TTHA1684 1 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 55981675 Common - putative divalent heavy-metal cation transporter TTHA1706 11 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 55981656 Common rplV 50S ribosomal protein L22 TTHA1687 221 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 55980881 Nonpathogen - hypothetical protein TTHA0912 1 None None None 55981396 Common - UvrD protein TTHA1427 230 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 55980304 Common - hypothetical protein TTHA0335 140 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 55981614 Common - MutS2 protein TTHA1645 202 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 55981739 Common - putative endopeptidase, family M23/M37 TTHA1770 193 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 55980479 Common - CsaA protein TTHA0510 135 COG0073 ARC1, EMAP domain General function prediction only 55981866 Common - GidA-related protein TTHA1897 94 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 55981046 Nonpathogen - hypothetical protein TTHA1077 1 None None None 55980444 Common - acetoin utilization protein AcuC (putative T-histone deacetylase) TTHA0475 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 55981465 Common - arginase TTHA1496 93 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 55980421 Common - branched-chain amino acid ABC transporter, ATP-binding protein TTHA0452 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 55980602 Nonpathogen - hypothetical protein TTHA0633 15 COG2250 COG2250, Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN Function unknown 55980550 Nonpathogen - hypothetical protein TTHA0581 1 None None None 55981040 Common - competence protein ComF TTHA1071 24 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 55980593 Nonpathogen - hypothetical protein TTHA0624 1 None None None 55981143 Common trkA potassium transporter peripheral membrane component TTHA1174 168 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 55980661 Common - fatty acid Co-A racemase related protein TTHA0692 109 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 55981509 Nonpathogen - hypothetical protein TTHA1540 1 None None None 55981825 Common - ABC transporter permease protein TTHA1856 108 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 55980559 Common - branched-chain amino acid ABC transporter amino acid-binding protein TTHA0590 122 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 55980272 Nonpathogen - hypothetical protein TTHA0303 3 None None None 55980907 Common - pyruvate dehydrogenase E1 component, beta subunit TTHA0938 167 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 55980178 Common rplJ 50S ribosomal protein L10 TTHA0209 215 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 55981662 Common rpsJ 30S ribosomal protein S10 TTHA1693 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 55980804 Common - hypothetical protein TTHA0835 50 COG0730 COG0730, Predicted permeases General function prediction only 55980163 Common - probable tripartite transporter, small subunit TTHA0194 73 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 55980900 Common trmE tRNA modification GTPase TrmE TTHA0931 221 COG0486 ThdF, Predicted GTPase General function prediction only 55981113 Common - acetyl-Coenzyme A dehydrogenase, medium chain TTHA1144 161 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 55980160 Common - dihydropteroate synthase TTHA0191 219 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 55980798 Common - putative acetoin utilization protein, acetoin dehydrogenase TTHA0829 196 COG0517 COG0517, FOG: CBS domain General function prediction only 55980897 Common - methyltransferase TTHA0928 193 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 55980280 Common - cytochrome caa3 oxidase subunit IIc TTHA0311 161 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 55980053 Common - NADH-quinone oxidoreductase chain 7 TTHA0084 156 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 55980125 Common - hypothetical protein TTHA0156 30 COG1846 MarR, Transcriptional regulators Transcription 55981207 Common - spermidine/putrescine ABC transporter, permease protein TTHA1238 113 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 55980220 Common - elongation factor Tu TTHA0251 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 55981119 Common - DNA polymerase beta family (X family) TTHA1150 81 COG1796 POL4, DNA polymerase IV (family X) DNA replication, recombination, and repair 55980676 Common - glutamine amidotransferase (pyridoxine biosynthesis) TTHA0707 85 COG0311 PDX2, Predicted glutamine amidotransferase involved in pyridoxine biosynthesis Coenzyme metabolism 55980616 Common - putative glycosyltransferase TTHA0647 31 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 55981490 Common - hypothetical protein TTHA1521 30 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 55980027 Common - transcriptional repressor of class I heat-shock genes TTHA0058 130 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 55980935 Common - phenylacetyl-CoA ligase TTHA0966 119 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 55981434 Common rplM 50S ribosomal protein L13 TTHA1465 233 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 55980788 Common - sodium/solute symporter TTHA0819 156 COG4147 DhlC, Predicted symporter General function prediction only 55981236 Nonpathogen - hypothetical protein TTHA1267 1 None None None 55980605 Common - hypothetical protein TTHA0636 23 None None None 55980957 Common - hypothetical protein TTHA0988 115 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 55980400 Common - sugar kinase TTHA0431 133 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 55981668 Common - hypothetical protein TTHA1699 120 COG2606 EbsC, Uncharacterized conserved protein Function unknown 55981345 Common - HD domain protein TTHA1376 124 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 55980255 Common - serine protease, subtilase family TTHA0286 83 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 55981731 Nonpathogen - hypothetical protein TTHA1762 11 None None None 55980050 Common - hypothetical protein TTHA0081 9 COG4712 COG4712, Uncharacterized protein conserved in bacteria Function unknown 55981708 Common - hypothetical protein TTHA1739 29 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 55980415 Common rpmH 50S ribosomal protein L34 TTHA0446 197 None None None 55981619 Common - maltose ABC transporter, permease protein TTHA1650 143 COG3833 MalG, ABC-type maltose transport systems, permease component Carbohydrate transport and metabolism 55981927 Common pheS phenylalanyl-tRNA synthetase subunit alpha TTHA1958 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 55980279 Common - cytochrome c oxidase assembly factor (CtaA) + protoheme IX farnesyltransferase (CtaB) TTHA0310 180 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 55980375 Common ruvB Holliday junction DNA helicase B TTHA0406 243 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 55980330 Common - survival protein SurE TTHA0361 142 COG0496 SurE, Predicted acid phosphatase General function prediction only 55981138 Common valS valyl-tRNA synthetase TTHA1169 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 55981086 Common - iron-sulfur protein TTHA1117 144 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 55980726 Nonpathogen - hypothetical protein TTHA0757 1 None None None 55980266 Common - acetylornithine deacetylase (ArgE) TTHA0297 196 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 55980171 Common - hypothetical protein TTHA0202 5 COG3177 COG3177, Uncharacterized conserved protein Function unknown 55980495 Common - glycine dehydrogenase subunit 2 TTHA0526 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 55981126 Common - immunogenic protein TTHA1157 91 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 55980688 Nonpathogen - hypothetical protein TTHA0719 2 None None None 55980002 Nonpathogen - hypothetical protein TTHA0033 1 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 55981094 Common - elongation factor P (EF-P) TTHA1125 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 161986604 Common rplD 50S ribosomal protein L4 TTHA1691 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 55980243 Nonpathogen - hypothetical protein TTHA0274 1 None None None 55980339 Common - thioredoxin reductase related protein TTHA0370 61 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 55980098 Common hisZ ATP phosphoribosyltransferase regulatory subunit TTHA0129 135 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 55980943 Common - integrase/recombinase TTHA0974 218 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 55981643 Nonpathogen rpmD 50S ribosomal protein L30 TTHA1674 5 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 55981323 Common - 3-dehydroquinate dehydratase TTHA1354 169 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 55981685 Nonpathogen - hypothetical protein TTHA1716 2 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 55980986 Common - hypothetical protein TTHA1017 70 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 55981796 Common - sugar ABC transporter permease protein TTHA1827 143 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 55980977 Common - ABC transporter, permease protein TTHA1008 168 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 55980342 Common - 3-octaprenyl-4-hydroxybenzoate carboxy-lyase UbiD TTHA0373 153 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 55981104 Common - ba3-type cytochrome c oxidase polypeptide I TTHA1135 156 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 55980569 Common hemH ferrochelatase TTHA0600 170 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 55980545 Common - putative pyruvyl-transferase TTHA0576 25 COG2327 WcaK, Uncharacterized conserved protein Function unknown 55981850 Common - hypothetical protein TTHA1881 39 COG3342 COG3342, Uncharacterized conserved protein Function unknown 55979992 Common - putative ATP-dependent protease La TTHA0023 116 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 55981058 Common - cell division protein FtsZ TTHA1089 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 55980096 Common - tRNA (guanosine-2'-O-) methyltransferase TTHA0127 208 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 55981244 Nonpathogen - V-type ATP synthase subunit TTHA1275 12 COG1527 NtpC, Archaeal/vacuolar-type H+-ATPase subunit C Energy production and conversion 55981913 Common - hypothetical protein TTHA1944 106 COG0393 COG0393, Uncharacterized conserved protein Function unknown 55980393 Common - thiamin-monophosphate kinase TTHA0424 109 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 55979970 Common - DNA polymerase III, beta subunit TTHA0001 208 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 55980839 Nonpathogen - hypothetical protein TTHA0870 1 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 55980791 Common - probable potassium efflux transporter TTHA0822 173 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 55981372 Common - cytochrome c biogenesis protein, thiol:disulfide interchange protein TTHA1403 163 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 55980061 Common - NADH-quinone oxidoreductase chain 9 TTHA0092 194 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 55981463 Common - putative protease TTHA1494 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 55980467 Nonpathogen - hypothetical protein TTHA0498 1 COG2250 COG2250, Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN Function unknown 55981577 Common - hypothetical protein TTHA1608 88 COG1430 COG1430, Uncharacterized conserved protein Function unknown 55980234 Nonpathogen - hypothetical protein TTHA0265 2 None None None 55980961 Common - putative fructokinase TTHA0992 50 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 55980824 Common - membrane-associated Zn-dependent protease TTHA0855 210 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 55981194 Common - hypothetical protein TTHA1225 26 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 55981625 Nonpathogen - hypothetical protein TTHA1656 1 None None None 55980042 Nonpathogen - hypothetical protein TTHA0073 1 None None None 55981289 Common - periplasmic serine protease TTHA1320 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 55981833 Nonpathogen - S-layer protein-related protein TTHA1864 5 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 55980994 Nonpathogen - hypothetical protein TTHA1025 1 None None None 55981351 Nonpathogen - competence protein PilW TTHA1382 2 COG5373 COG5373, Predicted membrane protein Function unknown 55980968 Nonpathogen - hypothetical protein TTHA0999 1 COG3857 AddB, ATP-dependent nuclease, subunit B DNA replication, recombination, and repair 55980181 Nonpathogen - hypothetical protein TTHA0212 8 COG3584 COG3584, Uncharacterized protein conserved in bacteria Function unknown 55981610 Common - GGDEF domain protein TTHA1641 175 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 55980756 Nonpathogen - hypothetical protein TTHA0787 1 None None None 55980879 Common - exoribonuclease TTHA0910 192 COG0557 VacB, Exoribonuclease R Transcription 55980599 Common hslU ATP-dependent protease ATP-binding subunit TTHA0630 212 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 55980843 Common - N-acylamino acid racemase TTHA0874 146 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 55980714 Common - hypothetical protein TTHA0745 4 None None None 55981358 Common - hypothetical protein TTHA1389 3 COG3296 COG3296, Uncharacterized protein conserved in bacteria Function unknown 55980883 Nonpathogen - hypothetical protein TTHA0914 1 None None None 55981071 Nonpathogen - hypothetical protein TTHA1102 2 None None None 55980413 Common - alpha-hemolysin TTHA0444 183 COG0759 COG0759, Uncharacterized conserved protein Function unknown 55980000 Nonpathogen - hypothetical protein TTHA0031 1 None None None 55981268 Common - ribose 5-phosphate isomerase TTHA1299 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 55981791 Nonpathogen - probable transporter TTHA1822 2 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 55981818 Nonpathogen - hypothetical protein TTHA1849 1 None None None 55981317 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase TTHA1348 201 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 55981188 Nonpathogen - probable general secretion pathway protein J TTHA1219 1 COG4795 PulJ, Type II secretory pathway, component PulJ Intracellular trafficking and secretion 55980327 Nonpathogen - hypothetical protein TTHA0358 1 None None None 55981029 Common - Mg2+ transporter MgtE TTHA1060 205 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 55980437 Nonpathogen - hypothetical protein TTHA0468 1 None None None 55980015 Common - aspartate aminotransferase TTHA0046 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 55980070 Common - transcriptional repressor, TetR family TTHA0101 88 COG1309 AcrR, Transcriptional regulator Transcription 55981930 Nonpathogen - hypothetical protein TTHA1961 1 None None None 55981591 Nonpathogen - probable thiosulfate sulfurtransferase TTHA1622 8 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 55981280 Nonpathogen - hypothetical protein TTHA1311 2 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 55980952 Common - L-aspartate oxidase TTHA0983 224 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 55980450 Common - oligo-1,6-glucosidase TTHA0481 169 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 55980515 Common - hemolysin TTHA0546 135 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 55980087 Common - exopolyphosphatase family protein TTHA0118 82 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 55981925 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit beta TTHA1956 107 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 55981906 Common - hypothetical protein TTHA1937 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 55980207 Nonpathogen - hypothetical protein TTHA0238 1 None None None 55981210 Common - rod shape determining protein RodA TTHA1241 205 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 55980363 Common - oxidoreductase, short-chain dehydrogenase/reductase family TTHA0394 28 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 55981422 Common sdhB succinate dehydrogenase iron-sulfur subunit TTHA1453 207 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 55981759 Common - 2-C-methyl-D-erythritol 2,4-cyclodiphoshate synthase TTHA1790 182 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 55980702 Common - transcriptional regulator MarR family TTHA0733 103 COG1846 MarR, Transcriptional regulators Transcription 55981608 Nonpathogen - hypothetical protein TTHA1639 1 None None None 55981226 Common - putative helicase TTHA1257 158 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 55980521 Common rpmI 50S ribosomal protein L35 TTHA0552 98 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 55980356 Common - Sec-independent protein translocase protein TatC TTHA0387 203 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 55980482 Common - phosphoribosylaminoimidazole carboxylase ATPase subunit TTHA0513 194 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 55980911 Nonpathogen - hypothetical protein TTHA0942 1 None None None 55980872 Common - probable hydrolase TTHA0903 52 COG0388 COG0388, Predicted amidohydrolase General function prediction only 55980287 Common - hypothetical protein TTHA0318 96 COG0391 COG0391, Uncharacterized conserved protein Function unknown 55981801 Nonpathogen - hypothetical protein TTHA1832 1 None None None 55981493 Common - serine hydroxymethyltransferase TTHA1524 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 55980526 Common - superoxide dismutase [Mn] TTHA0557 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 55980457 Common - antitoxin of toxin-antitoxin stability system TTHA0488 7 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 55980079 Common - molybdopterin biosynthesis MoeA TTHA0110 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 55980153 Common - branched-chain alpha-keto acid dehydrogenase subunit E2 TTHA0184 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 55980923 Nonpathogen - mannosyl-3-phosphoglycerate synthase TTHA0954 5 None None None 55981875 Nonpathogen - hypothetical protein TTHA1906 2 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 55980489 Common - NAD-dependent malic enzyme (malate dehydrogenase) TTHA0520 196 COG0281 SfcA, Malic enzyme Energy production and conversion 55981670 Nonpathogen - hypothetical protein TTHA1701 1 None None None 55980770 Common - hypothetical protein TTHA0801 44 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 55981452 Nonpathogen - conserved putative protein TTHA1483 3 COG2129 COG2129, Predicted phosphoesterases, related to the Icc protein General function prediction only 55981513 Nonpathogen - hypothetical protein TTHA1544 1 None None None 55980104 Common - MutT/nudix family protein TTHA0135 29 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 55981714 Nonpathogen - hypothetical protein TTHA1745 47 COG1371 COG1371, Uncharacterized conserved protein Function unknown 55981257 Common - exonuclease SbcC TTHA1288 88 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 55980188 Common - ribosomal large subunit pseudouridine synthase B TTHA0219 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 55980651 Nonpathogen - hypothetical protein TTHA0682 1 None None None 55980736 Common - putative small integral membrane tranport protein TTHA0767 58 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 55981416 Common - alanine dehydrogenase TTHA1447 165 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 55980962 Common - hypothetical protein TTHA0993 46 COG5621 COG5621, Predicted secreted hydrolase General function prediction only 55981620 Common - maltose ABC transporter, permease protein TTHA1651 140 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 55980383 Common - acyl carrier protein TTHA0414 210 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 55980532 Common - conserved hypothetical protein (TIM-barrel fold) TTHA0563 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 55981895 Common - ATP:cob(I)alamin adenosyltransferase TTHA1926 130 COG2096 COG2096, Uncharacterized conserved protein Function unknown 55981777 Common - ABC transporter, periplasmic substrate-binding protein TTHA1808 80 COG4143 TbpA, ABC-type thiamine transport system, periplasmic component Coenzyme metabolism 55981553 Nonpathogen - Type II restriction enzyme TthHB8I (endonuclease TthHB8I) (R.TthHB8I) TTHA1584 1 None None None 55981051 Common - UDP-N-acetylmuramoylalanine--D-glutamiate ligase TTHA1082 208 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 55981252 Common - hypothetical protein TTHA1283 114 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 55980832 Common - MutT/nudix family protein TTHA0863 40 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 55981124 Common - mercuric resistance operon regulatory protein (MerR) TTHA1155 135 COG0789 SoxR, Predicted transcriptional regulators Transcription 55981476 Common - probable uroporphyrinogen III synthase TTHA1507 14 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 55981832 Nonpathogen - hypothetical protein TTHA1863 1 None None None 55981386 Common - sulfur oxidation protein SoxB TTHA1417 104 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 55981937 Common - competence protein ComEC TTHA1968 111 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 55981429 Common - ABC transporter, permease protein TTHA1460 12 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 55980960 Common - hypothetical protein TTHA0991 72 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 55981131 Common - excisionase domain protein TTHA1162 31 None None None 55980332 Common - putative hydrolase, HAD superfamily TTHA0363 42 COG2179 COG2179, Predicted hydrolase of the HAD superfamily General function prediction only 55981011 Common - anti-cleavage anti-GreA transcription factor Gfh1 TTHA1042 179 COG0782 GreA, Transcription elongation factor Transcription 55981716 Common - thioredoxin TTHA1747 234 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 55980349 Common - aldehyde:ferredoxin oxidoreductase TTHA0380 57 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 55981562 Common - hypothetical protein TTHA1593 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 55979984 Common - LytB protein TTHA0015 187 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 55980959 Nonpathogen - hypothetical protein TTHA0990 8 None None None 55981604 Common - iron-sulfur cluster biosynthesis protein IscA TTHA1635 167 COG0316 IscA, Uncharacterized conserved protein Function unknown 55980222 Nonpathogen - hypothetical protein TTHA0253 1 None None None 55980289 Common - methionyl-tRNA formyltransferase TTHA0320 220 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 55981740 Common - pyrimidine-nucleoside (thymidine) phosphorylase TTHA1771 118 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 55980509 Common - hypothetical protein TTHA0540 43 COG4956 COG4956, Integral membrane protein (PIN domain superfamily) General function prediction only 55980156 Common - putative protein phosphatase TTHA0187 139 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 55980892 Nonpathogen - hypothetical protein TTHA0923 1 None None None 55981450 Common - thioredoxin TTHA1481 235 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 55981823 Common - ubiquinone/menaquinone biosynthesis methyltransferase TTHA1854 223 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 55981557 Common - peptidyl-tRNA hydrolase TTHA1588 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 55981383 Common - putative sulfurtransferase TTHA1414 124 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 55981920 Nonpathogen - hypothetical protein TTHA1951 1 None None None 55981223 Nonpathogen - hypothetical protein TTHA1254 2 None None None 55981255 Common - virulence factor-related protein TTHA1286 170 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 55980314 Common - porphobilinogen deaminase TTHA0345 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 55981546 Common - putative NAD-dependent glutamate dehydrogenase TTHA1577 165 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 55980979 Common - hypothetical protein TTHA1010 74 COG1511 COG1511, Predicted membrane protein Function unknown 55980078 Common - ATP-dependent RNA helicase TTHA0109 245 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 55980235 Common - cell wall-binding endopeptidase-related protein TTHA0266 165 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 55980326 Nonpathogen - hypothetical protein TTHA0357 1 None None None 55981294 Common - putaitve sulfite oxidase TTHA1325 88 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 55981542 Nonpathogen - hypothetical protein TTHA1573 1 None None None 55980731 Common - short chain dehydrogenase TTHA0762 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 55981229 Common - DNA primase TTHA1260 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 55981550 Nonpathogen - hypothetical protein TTHA1581 7 None None None 55981128 Common - amino acid ABC transporter, ATP-binding protein TTHA1159 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 55981219 Common - acetyl-coenzyme A synthetase TTHA1250 216 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 55980195 Nonpathogen - hypothetical protein TTHA0226 13 COG4911 COG4911, Uncharacterized conserved protein Function unknown 55981179 Common - 2-isopropylmalate synthase TTHA1210 214 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 55980118 Nonpathogen - hypothetical protein TTHA0149 1 None None None 55981496 Common - NADPH-quinone reductase TTHA1527 186 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 55981929 Nonpathogen - hypothetical protein TTHA1960 1 None None None 55980477 Common - transcriptional regulator, MerR family TTHA0508 82 COG0789 SoxR, Predicted transcriptional regulators Transcription 55981914 Nonpathogen - hypothetical protein TTHA1945 1 None None None 55979977 Common - phage shock protein A TTHA0008 75 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 55981070 Nonpathogen - hypothetical protein TTHA1101 2 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 55980430 Common - dihydropteridine/dihydrofolate reductase TTHA0461 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 55980999 Common - response regulator TTHA1030 193 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 55980820 Common - Sun protein (RNA methyltransferase) TTHA0851 202 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 55981942 Common - chromosomal replication initiator protein DnaA TTHA1973 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 55980365 Nonpathogen - hypothetical protein TTHA0396 2 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 55981411 Common - tRNA (uracil-5-)-methyltransferase Gid TTHA1442 192 COG1206 Gid, NAD(FAD)-utilizing enzyme possibly involved in translation Translation, ribosomal structure and biogenesis 55981089 Common - methylenetetrahydrofolate dehydrogenase (NADP+)/methenyltetrahydrofolate cyclohydrolase TTHA1120 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 55980464 Nonpathogen - 2-phosphoglycerate kinase TTHA0495 14 COG2074 COG2074, 2-phosphoglycerate kinase Carbohydrate transport and metabolism 55980490 Nonpathogen - hypothetical protein TTHA0521 5 COG2380 COG2380, Uncharacterized protein conserved in bacteria Function unknown 55981197 Common - isopropylmalate isomerase large subunit TTHA1228 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 55980851 Common - glycosyltransferase TTHA0882 170 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 55981467 Common - elongation factor G TTHA1498 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 55980049 Nonpathogen - hypothetical protein TTHA0080 1 None None None 55980299 Nonpathogen - hypothetical protein TTHA0330 2 None None None 55981460 Common - chaperone protein DnaK (heat shock protein 70) TTHA1491 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 55980134 Common - hypothetical protein TTHA0165 8 COG2389 COG2389, Uncharacterized metal-binding protein General function prediction only 55980273 Common - enoyl-[acyl carrier protein] reductase TTHA0304 235 COG0623 FabI, Enoyl- acyl-carrier-protein 55981831 Nonpathogen - hypothetical protein TTHA1862 1 None None None 55981312 Common - citrate synthase TTHA1343 194 COG0372 GltA, Citrate synthase Energy production and conversion 55981248 Nonpathogen - V-type ATP synthase, subunit (VAPC-THERM) TTHA1279 1 None None None 55980200 Nonpathogen - 2-oxoisovalerate dehydrogenase, E1 component beta subunit TTHA0231 7 None None None 55980990 Nonpathogen - hypothetical protein TTHA1021 1 None None None 55980452 Common - probable transcriptional regulator, ArsR family TTHA0483 63 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 55981898 Nonpathogen - hypothetical protein TTHA1929 1 COG1295 Rbn, Predicted membrane protein Function unknown 55981872 Common - acetylglutamate kinase TTHA1903 210 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 55981390 Common - sulfur oxidation protein SoxY TTHA1421 39 COG5501 COG5501, Predicted secreted protein Function unknown 55981096 Nonpathogen - hypothetical protein TTHA1127 1 None None None 55980970 Nonpathogen - hypothetical protein TTHA1001 1 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 55980574 Common - 4-hydroxybenzoate octaprenyltransferase TTHA0605 76 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 55980967 Common - ATP-dependent DNA helicase TTHA0998 220 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 55980439 Common - peptide ABC transporter, permease protein TTHA0470 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 55981379 Common - sulfite dehydrogenase cytochrome subunit SoxD TTHA1410 33 COG3258 COG3258, Cytochrome c Energy production and conversion 55981537 Common - hypothetical protein TTHA1568 41 COG2107 COG2107, Predicted periplasmic solute-binding protein General function prediction only 55980793 Common - spermidine synthase TTHA0824 128 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 55981623 Common - nucleoside-triphosphatase (HAM1 protein) TTHA1654 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 55980017 Common - hypothetical protein TTHA0048 35 None None None 55981190 Nonpathogen - pilin, type IV, putative TTHA1221 1 COG4537 ComGC, Competence protein ComGC Intracellular trafficking and secretion 55981410 Nonpathogen - hypothetical protein TTHA1441 2 COG1808 COG1808, Predicted membrane protein Function unknown 55980888 Nonpathogen - hypothetical protein TTHA0919 1 None None None 55980745 Nonpathogen - hypothetical protein TTHA0776 1 None None None 55980858 Common - transcription-repair coupling factor TTHA0889 220 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 55980047 Nonpathogen - hypothetical protein TTHA0078 4 COG5551 COG5551, Uncharacterized conserved protein Function unknown 55981877 Nonpathogen - hypothetical protein TTHA1908 9 COG1405 SUA7, Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB Transcription 55980127 Common - alpha-dextran endo-1,6-alpha-glucosidase ((amylo)pullulanase) TTHA0158 44 COG1449 COG1449, Alpha-amylase/alpha-mannosidase Carbohydrate transport and metabolism 55981749 Common - hypothetical protein TTHA1780 186 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 55981420 Nonpathogen - hypothetical protein TTHA1451 1 None None None 55981053 Common - UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase TTHA1084 98 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 55980933 Common - ABC tranpsorter ATP binding protein related protein TTHA0964 232 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 55981025 Common - putative phosphoglucosamine mutase/phosphoacetylglucosamine mutase/phosphomannomutase TTHA1056 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 55980392 Nonpathogen - hypothetical protein TTHA0423 1 COG2045 COG2045, Phosphosulfolactate phosphohydrolase and related enzymes Coenzyme metabolism / General function prediction only 55980823 Common - glycosyltransferase TTHA0854 30 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 55981571 Nonpathogen - hypothetical protein TTHA1602 2 None None None 55981523 Common - hypothetical protein TTHA1554 13 COG4274 COG4274, Uncharacterized conserved protein Function unknown 55981585 Common - putative acid phosphatase precursor TTHA1616 26 COG1409 Icc, Predicted phosphohydrolases General function prediction only 55980410 Common - methyltransferase, HemK family TTHA0441 213 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 55981771 Nonpathogen - hypothetical protein TTHA1802 1 None None None 55981008 Common - methylmalonyl-CoA mutase, alpha subunit, chain A TTHA1039 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 55981328 Common - transcriptional regulator, FNR/CRP family TTHA1359 115 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 55980155 Common - probable transcriptional regulator TTHA0186 91 COG0583 LysR, Transcriptional regulator Transcription 55980112 Common - phosphate transport system regulatory protein PhoU TTHA0143 198 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 55981732 Common - molybdopterin oxidoreductase membrane subunit TTHA1763 41 COG5557 COG5557, Polysulphide reductase Energy production and conversion 55980848 Common - putative oligosaccharide deacetylase TTHA0879 88 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 55980196 Nonpathogen - hypothetical protein TTHA0227 2 None None None 55980938 Common - phenylacetic acid degradation protein PaaD TTHA0969 53 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 55980037 Nonpathogen - hypothetical protein TTHA0068 3 None None None 55981148 Common - probable fructosamine-3-kinase TTHA1179 69 COG3001 COG3001, Uncharacterized protein conserved in bacteria Function unknown 55980246 Common - glucose-6-phosphate isomerase TTHA0277 210 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 55980683 Nonpathogen - hypothetical protein TTHA0714 1 None None None 55981241 Common - V-type ATP synthase subunit B TTHA1272 247 COG1156 NtpB, Archaeal/vacuolar-type H+-ATPase subunit B Energy production and conversion 55979994 Nonpathogen - hypothetical protein TTHA0025 1 COG3180 AbrB, Putative ammonia monooxygenase General function prediction only 55980282 Nonpathogen - hypothetical protein TTHA0313 3 None None None 55980496 Common - riboflavin kinase/FMN adenylyltransferase TTHA0527 210 COG0196 RibF, FAD synthase Coenzyme metabolism 55981133 Common - indole-3-glycerol phosphate synthase TTHA1164 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 55980055 Common - NADH-quinone oxidoreductase chain 5 TTHA0086 181 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 55981299 Common - branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein TTHA1330 138 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 55981449 Common - small heat shock protein, HSP20 family TTHA1480 84 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 55981272 Common - sugar ABC transporter, permease protein TTHA1303 103 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 55980007 Nonpathogen - hypothetical protein TTHA0038 1 None None None 55980640 Common hemD uroporphyrinogen-III synthase TTHA0671 14 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 55980305 Common - riboflavin synthase, beta subunit (6,7-dimethyl-8-ribityllumazine synthase (RibH)) TTHA0336 228 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 55981109 Common - metallo-beta-lactamase superfamily protein TTHA1140 155 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 55981080 Common - alternative ATP-dependent protease La (Lon protease) TTHA1111 205 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 55981645 Common rplR 50S ribosomal protein L18 TTHA1676 215 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 55980649 Common - phosphomethylpyrimidine kinase (ThiD) TTHA0680 217 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 55981196 Common - tryptophanyl-tRNA synthetase TTHA1227 247 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 55981637 Common rpmJ 50S ribosomal protein L36 TTHA1668 140 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 55980870 Nonpathogen - hypothetical protein TTHA0901 1 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 55980985 Common - hypothetical protein TTHA1016 46 COG1743 COG1743, Adenine-specific DNA methylase containing a Zn-ribbon DNA replication, recombination, and repair 55980949 Common - hypothetical protein TTHA0980 37 COG1980 COG1980, Archaeal fructose 1,6-bisphosphatase Carbohydrate transport and metabolism 55980552 Common - hypothetical protein TTHA0583 16 COG4475 COG4475, Uncharacterized protein conserved in bacteria Function unknown 55980681 Common hisS histidyl-tRNA synthetase TTHA0712 248 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 55981108 Common - polynucleotide phosphorylase/polyadenylase TTHA1139 238 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 55980379 Nonpathogen - hypothetical protein TTHA0410 1 None None None 55981156 Common - hypothetical protein TTHA1187 97 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 55981098 Common - agmatinase (SpeB) TTHA1129 158 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 55980677 Common asnC asparaginyl-tRNA synthetase TTHA0708 249 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 55980404 Common - disulfide bond formation protein B TTHA0435 21 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 55981164 Nonpathogen - hypothetical protein TTHA1195 2 None None None 55980480 Common - probable phenylaceate-CoA ligase/coenzyme F390 synthetase TTHA0511 111 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 55981332 Common - sensor histidine kinase TTHA1363 181 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 55981606 Common - ribose-phosphate pyrophosphokinase TTHA1637 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 55980231 Common - probable phosphate ABC transporter, ATP-binding protein TTHA0262 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 55981518 Common - ribose-phosphate pyrophosphokinase TTHA1549 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 55980563 Common - putative periplasmid solute-binding protein TTHA0594 76 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 55980169 Common - molybdopterin oxidoreductase TTHA0200 183 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 55980603 Common - magnesium chelatase related protein TTHA0634 38 COG1239 ChlI, Mg-chelatase subunit ChlI Coenzyme metabolism 55980258 Common kgd alpha-ketoglutarate decarboxylase TTHA0289 147 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 55980720 Nonpathogen - hypothetical protein TTHA0751 1 None None None 55980590 Nonpathogen - putative 4-amino-4-deoxychorismate lyase TTHA0621 6 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 55980954 Common - nicotinate-nucleotide pyrophosphorylase [carboxylating] TTHA0985 203 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 55980271 Nonpathogen - hypothetical protein TTHA0302 1 None None None 55981919 Common - N-acetylglutamate kinase (ArgB-2) TTHA1950 125 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 55980527 Common fumC fumarate hydratase TTHA0558 232 COG0114 FumC, Fumarase Energy production and conversion 55980931 Common - homoprotocatechuate 2,3-dioxygenase TTHA0962 36 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 55981693 Nonpathogen - hypothetical protein TTHA1724 1 None None None 55980182 Nonpathogen - hypothetical protein TTHA0213 1 None None None 55981701 Common - hypothetical protein TTHA1732 42 COG3439 COG3439, Uncharacterized conserved protein Function unknown 55981176 Common - hypothetical protein TTHA1207 20 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 55981724 Common - acetylornithine/acetyl-lysine aminotransferase TTHA1755 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 55980469 Common - glycerate dehydrogenase/hydroxypyruvate reductase TTHA0500 86 COG2379 GckA, Putative glycerate kinase Carbohydrate transport and metabolism 55981855 Common - ABC transporter, permease protein TTHA1886 137 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 55981673 Nonpathogen - hypothetical protein TTHA1704 1 None None None 55980209 Common - lipoate-protein ligase B TTHA0240 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 55981230 Common - 4-alpha-glucanotransferase (amylomaltase) (disproportionating enzyme) (D-enzyme) TTHA1261 120 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 55980213 Common - single-stranded DNA binding protein TTHA0244 188 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 55981860 Nonpathogen - hypothetical protein TTHA1891 2 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 55979993 Common - penicillin acylase II precursor TTHA0024 76 COG2366 COG2366, Protein related to penicillin acylase General function prediction only 55980475 Common - malate synthase TTHA0506 68 COG2225 AceB, Malate synthase Energy production and conversion 55980177 Common - nicotinamide nucleotide transhydrogenase, beta subunit TTHA0208 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 55981431 Common - putative phosphoribosyltransferase TTHA1462 63 COG1926 COG1926, Predicted phosphoribosyltransferases General function prediction only 55981767 Common - transport protein TTHA1798 37 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 55980597 Nonpathogen - Sec-independent protein translocase protein TTHA0628 2 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 55981616 Common - putative maltodextrin glucosidase TTHA1647 148 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 55981203 Common - dihydroxyacid dehydratase TTHA1234 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 55981908 Nonpathogen - MutT/nudix family protein TTHA1939 3 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 55980504 Common - purine phosphoribosyltransferase (xanthine-guanine phosphoribosyltransferase) TTHA0535 34 COG2236 COG2236, Predicted phosphoribosyltransferases General function prediction only 55981822 Common - arsenate reductase TTHA1853 127 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 55981303 Common - branched-chain amino acid ABC transporter, ATP-binding protein TTHA1334 203 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 55980600 Common - ATP-dependent protease peptidase subunit TTHA0631 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 55981005 Common - signal recognition particle protein TTHA1036 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 55980540 Common - probable small heat shock protein TTHA0571 91 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 55980131 Common rpsA 30S ribosomal protein S1 TTHA0162 216 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 55980806 Common - metallo-beta-lactamase family protein TTHA0837 212 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 55981287 Nonpathogen - hypothetical protein TTHA1318 1 None None None 55980426 Common - 3-phosphoshikimate 1-carboxyvinyltransferase TTHA0457 222 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 55979978 Nonpathogen - hypothetical protein TTHA0009 1 None None None 55981047 Common - penicillin-binding protein TTHA1078 206 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 55981560 Nonpathogen - hypothetical protein TTHA1591 1 None None None 55981250 Nonpathogen - hypothetical protein TTHA1281 2 None None None 55980636 Common - hypothetical protein TTHA0667 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 55981186 Nonpathogen - prepilin-like protein TTHA1217 1 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 55981265 Common - carboxyl-terminal protease TTHA1296 187 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 55980707 Nonpathogen - hypothetical protein TTHA0738 1 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 55980348 Common - sugar ABC transporter, periplasmic sugar-binding protein TTHA0379 109 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 55981444 Common - hypothetical protein TTHA1475 45 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 55981657 Common rpsS 30S ribosomal protein S19 TTHA1688 248 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 55980534 Common - hypothetical protein TTHA0565 76 COG1434 COG1434, Uncharacterized conserved protein Function unknown 55980310 Common - molybdopterin biosynthesis enzyme, MoaB TTHA0341 189 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 55981773 Common - probable acyl-CoA thioesterase TTHA1804 123 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 55980819 Common - stage V sporulation protein S (SpoVS) related protein TTHA0850 24 COG2359 SpoVS, Uncharacterized protein conserved in bacteria Function unknown 55981406 Common - transcription regulator, Crp family TTHA1437 151 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 55980146 Common - ferredoxin TTHA0177 157 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 55981481 Common - putative nucleotidyltransferase TTHA1512 40 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 55980904 Common - quaternary ammonium compound-resistance protein TTHA0935 124 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 55980920 Common - DegV family protein TTHA0951 51 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 55981812 Common - anthranilate synthase component II (TrpG) TTHA1843 232 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 55981609 Common - arginine decarboxylase TTHA1640 151 COG1166 SpeA, Arginine decarboxylase (spermidine biosynthesis) Amino acid transport and metabolism 55980333 Common - type IV pilus assembly protein PilF TTHA0364 204 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 55981576 Common - probable thymidylate kinase (TMP kinase) TTHA1607 234 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 55981373 Common - cytochrome c-type biogenesis protein CcmF TTHA1404 145 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 55980917 Common - fatty acid desaturase TTHA0948 39 COG3239 DesA, Fatty acid desaturase Lipid metabolism 55980776 Common - transcriptional regulator TTHA0807 127 COG1609 PurR, Transcriptional regulators Transcription 55980914 Nonpathogen - hypothetical protein TTHA0945 1 None None None 55981394 Common - putative thiamine pyrophosphokinase TTHA1425 18 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 55981367 Nonpathogen - hypothetical protein TTHA1398 1 None None None 55980698 Common - probable efflux transporter, AcrB/AcrD/AcrF family TTHA0729 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 55980655 Common - sugar ABC transporter, permease protein [C-terminal] TTHA0686 133 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 55980862 Common cysS cysteinyl-tRNA synthetase TTHA0893 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 55981430 Common - hypothetical protein TTHA1461 51 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 55980571 Common - peptidyl-prolyl cis-trans isomerase TTHA0602 127 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 55981458 Common - chaperone protein DnaJ TTHA1489 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 55980841 Common - amidohydrolase family protein TTHA0872 157 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 55980725 Common - beta-lactamase related protein TTHA0756 8 COG2367 PenP, Beta-lactamase class A Defense mechanisms 55981630 Common - conserved hypothetical protein, integral membrane protein TTHA1661 39 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 55980224 Common - ferric uptake regulation protein TTHA0255 181 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 55981512 Nonpathogen - hypothetical protein TTHA1543 1 None None None 55981169 Common - hypothetical protein TTHA1200 63 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 55980294 Nonpathogen - hypothetical protein TTHA0325 1 None None None 55981065 Common thyX FAD-dependent thymidylate synthase TTHA1096 57 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 55980264 Common - universal stress protein UspA-like protein TTHA0295 158 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 55980459 Common - hypothetical protein TTHA0490 12 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 55980019 Common - phosphoglycerate mutase family protein TTHA0050 42 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 55980193 Common - glucose-1-phosphate thymidylyltransferase TTHA0224 236 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 55981804 Common - NADH oxidase TTHA1835 245 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 55981183 Nonpathogen - hypothetical protein TTHA1214 1 None None None 55981544 Common - kanamycin resistance protein-related protein TTHA1575 71 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 55980284 Nonpathogen - hypothetical protein TTHA0315 2 None None None 55981474 Nonpathogen - cytochrome c assembly protein-related protein TTHA1505 1 None None None 55981747 Common - LytR/CspA/Psr family protein TTHA1778 42 COG1316 LytR, Transcriptional regulator Transcription 55980081 Common - endonuclease III TTHA0112 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 55981055 Common - UDP-N-acetylenolpyruvoylglucosamine reductase TTHA1086 193 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 55981462 Common - hypothetical protein TTHA1493 109 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 55980142 Common - aminotransferase, class V TTHA0173 164 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 55981548 Common - putative proline dehydrogenase (monofunctional) TTHA1579 81 COG0506 PutA, Proline dehydrogenase Amino acid transport and metabolism 55981296 Common - hypothetical protein TTHA1327 26 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 55981935 Nonpathogen - hypothetical protein TTHA1966 1 None None None 55981216 Nonpathogen - hypothetical protein TTHA1247 1 None None None 55981718 Common - 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (FolK) TTHA1749 192 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 55981165 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein TTHA1196 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 55980525 Nonpathogen - hypothetical protein TTHA0556 5 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 55980068 Common - serine protease TTHA0099 220 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 55981521 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein TTHA1552 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 55980784 Common - sensor histidine kinase TTHA0815 174 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 55981227 Nonpathogen - hypothetical protein TTHA1258 2 None None None 55980722 Common - probable L-allo-threonine aldolase TTHA0753 72 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 55980678 Common - putative hydrolase TTHA0709 93 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 55981177 Common - putative alpha-isopropylmalate/homocitrate synthase family transferase TTHA1208 189 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 55981940 Common - glucose inhibited division protein B TTHA1971 175 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 55981217 Common - acetyl-coenzyme A synthetase TTHA1248 214 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 55980549 Nonpathogen - hypothetical protein TTHA0580 1 None None None 55981305 Common - peptide ABC transporter oligopeptide-binding protein TTHA1336 210 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 55981792 Common - putative hydrolase (phosphatase) TTHA1823 212 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 55981222 Nonpathogen - hypothetical protein TTHA1253 1 None None None 55979982 Common - geranylgeranyl diphosphate synthetase TTHA0013 226 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 55981528 Common - arginine repressor/activator TTHA1559 81 COG1438 ArgR, Arginine repressor Transcription 55980876 Nonpathogen - ribosome-binding factor A TTHA0907 1 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 55980367 Nonpathogen - hypothetical protein TTHA0398 1 COG0795 COG0795, Predicted permeases General function prediction only 55981428 Common - ABC transporter, ATP-binding protein TTHA1459 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 55981413 Common - imidazoleglycerol-phosphate synthase (HisF cyclase) TTHA1444 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 55980094 Nonpathogen - hypothetical protein TTHA0125 1 None None None 55980158 Common - hypothetical protein TTHA0189 66 COG1432 COG1432, Uncharacterized conserved protein Function unknown 55980454 Common - phosphoesterase-related protein TTHA0485 26 COG0622 COG0622, Predicted phosphoesterase General function prediction only 55981559 Nonpathogen - hypothetical protein TTHA1590 1 None None None 55981891 Nonpathogen - hypothetical protein TTHA1922 2 None None None 55980740 Nonpathogen - hypothetical protein TTHA0771 2 COG3629 DnrI, DNA-binding transcriptional activator of the SARP family Signal transduction mechanisms 55981922 Common - hypothetical protein TTHA1953 18 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 55980747 Nonpathogen - hypothetical protein TTHA0778 2 None None None 55980101 Common - hypothetical protein TTHA0132 112 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 55981843 Common - hypothetical protein TTHA1874 30 None None None 55980358 Common - polyferredoxin TTHA0389 30 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 55981192 Common - hypothetical protein TTHA1223 89 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 55981352 Common - general secretion pathway protein (PilQ) TTHA1383 142 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 55981729 Common - hypothetical protein TTHA1760 18 None None None 55981917 Nonpathogen - hypothetical protein TTHA1948 1 None None None 55981370 Common - cytochrome c family protein TTHA1401 15 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 55981621 Common - maltose ABC transporter, periplasmic maltose-binding protein TTHA1652 107 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 55980537 Common - hypothetical protein TTHA0568 6 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 55980626 Common - hypothetical protein TTHA0657 129 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 55980390 Nonpathogen - hypothetical protein TTHA0421 3 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 55980316 Common - O-acetylserine (thiol)-lyase (cysteine synthase) TTHA0347 220 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 55980516 Nonpathogen - hypothetical protein TTHA0547 1 None None None 55981578 Nonpathogen - hypothetical protein TTHA1609 1 COG1430 COG1430, Uncharacterized conserved protein Function unknown 55980886 Nonpathogen - hypothetical protein TTHA0917 1 None None None 55981573 Common - hypothetical protein TTHA1604 10 None None None 55980174 Common - hypothetical protein TTHA0205 22 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 55980789 Common - hypothetical protein TTHA0820 43 COG4327 COG4327, Predicted membrane protein Function unknown 55980751 Common pyrB aspartate carbamoyltransferase catalytic subunit TTHA0782 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 55980716 Common - iron ABC transporter, permease protein TTHA0747 162 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 55980010 Common - hypothetical protein TTHA0041 11 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 55980106 Common - protein translation intiation inhibitor TTHA0137 190 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 55981377 Common - ABC transporter, ATP-binding protein TTHA1408 238 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 55981488 Common - phosphoribosylformylglycinamidine synthase II TTHA1519 235 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 55980795 Common - cell division protein FtsK TTHA0826 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 55981587 Common - hypothetical protein TTHA1618 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 55981853 Common - recombination factor protein RarA TTHA1884 228 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 55980585 Common clpX ATP-dependent protease ATP-binding subunit TTHA0616 234 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 55980857 Common - pyrrolidone carboxyl peptidase TTHA0888 55 COG2039 Pcp, Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) Posttranslational modification, protein turnover, chaperones 55980997 Common - thiosulfate sulfurtransferase TTHA1028 146 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 55979975 Common - 1-deoxy-D-xylulose-5-phosphate synthase TTHA0006 227 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 55981697 Common - hypothetical protein TTHA1728 182 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 55980132 Common - hypothetical protein TTHA0163 188 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 55981778 Common - proline iminopeptidase-related protein TTHA1809 95 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 55981448 Nonpathogen - hypothetical protein TTHA1479 11 None None None 55980644 Nonpathogen - putative thiamine biosynthesis protein ThiS TTHA0675 3 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 55980040 Common - ABC-transporter, ATP-binding subunit TTHA0071 24 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 55980890 Common - transposase (probable DNA-binding protein 1A) TTHA0921 72 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 55980398 Common - Imidazoleglycerol-phosphate dehydratase TTHA0429 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 55981682 Common - hypothetical protein TTHA1713 106 COG0432 COG0432, Uncharacterized conserved protein Function unknown 55980259 Common - probable enoyl-CoA hydratase TTHA0290 180 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 55980377 Common - ribosomal large subunit pseudouridine synthase D TTHA0408 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 55980045 Common - phosphoribosylanthranilate isomerase TTHA0076 150 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 55980507 Common - succinyl-CoA synthetase beta chain TTHA0538 212 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 55980215 Common rplA 50S ribosomal protein L1 TTHA0246 229 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 55981838 Nonpathogen - hypothetical protein TTHA1869 1 None None None 55980572 Nonpathogen - hypothetical protein TTHA0603 3 COG0388 COG0388, Predicted amidohydrolase General function prediction only 55981498 Nonpathogen - hypothetical protein TTHA1529 1 None None None 55980899 Common - phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase TTHA0930 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 55980184 Common - alkaline shock protein TTHA0215 27 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 55981237 Common - hypothetical protein TTHA1268 8 None None None 55980766 Common - (s)-2-hydroxy-acid oxidase subunit (GlcD) TTHA0797 200 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 55980202 Common - pyruvate dehydrogenase complex, dihydrolipoamide dehydrogenase E3 component TTHA0233 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 55980276 Common - uracil permease [N-terminal] TTHA0307 101 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 55980973 Nonpathogen - hypothetical protein TTHA1004 1 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 55981901 Nonpathogen - probable c-type cytochrome TTHA1932 2 None None None 55981039 Common - hypothetical protein TTHA1070 35 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 55981154 Common - translation-associated GTPase TTHA1185 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 55980252 Common - argininosuccinate lyase TTHA0283 229 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 55981783 Common - hypothetical protein TTHA1814 12 COG2302 COG2302, Uncharacterized conserved protein, contains S4-like domain Function unknown 55981174 Common - ABC transporter, ATP-binding protein TTHA1205 249 COG4586 COG4586, ABC-type uncharacterized transport system, ATPase component General function prediction only 55981760 Common - putative hydrolase (HD domain) TTHA1791 31 COG2316 COG2316, Predicted hydrolase (HD superfamily) General function prediction only 55981599 Common - iron ABC transporter, ATP-binding protein TTHA1630 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 55980554 Common - branched-chain amino acid ABC transporter, permease protein TTHA0585 128 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 55981689 Common - cation-transporting ATPase TTHA1720 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 55981745 Nonpathogen - hypothetical protein TTHA1776 1 None None None 55980936 Common - hypothetical protein TTHA0967 16 COG5496 COG5496, Predicted thioesterase General function prediction only 55980167 Common - ribonuclease HII TTHA0198 208 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 55981076 Nonpathogen - hypothetical protein TTHA1107 2 None None None 55980035 Nonpathogen - hypothetical protein TTHA0066 1 None None None 55980808 Common - phage shock protein E (rhodanese-like domain protein) TTHA0839 186 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 55980448 Common - trehalose-6-phosphate phosphatase TTHA0479 84 COG1877 OtsB, Trehalose-6-phosphatase Carbohydrate transport and metabolism 55980846 Common - hypothetical protein TTHA0877 37 COG1811 COG1811, Uncharacterized membrane protein, possible Na+ channel or pump General function prediction only 55980518 Common - glutaminyl-tRNA synthetase TTHA0549 240 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 55981121 Common - aminopeptidase T TTHA1152 56 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 55980592 Nonpathogen - DNA repair protein RecO TTHA0623 2 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 55980164 Common - probable tripartite transporter, large subunit TTHA0195 135 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 55981691 Common - putative response regulator TTHA1722 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 55981232 Common - hypothetical protein TTHA1263 23 COG2510 COG2510, Predicted membrane protein Function unknown 55981755 Nonpathogen - hypothetical protein TTHA1786 4 COG4632 EpsL, Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Carbohydrate transport and metabolism 55981722 Common - probable glycosyltransferase TTHA1753 44 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 55980780 Common - phosphoribosylglycinamide formyltransferase (PurD) TTHA0811 220 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 55981326 Nonpathogen - hypothetical protein TTHA1357 4 None None None 55980114 Common - phosphate regulon transcriptional regulatory protein PhoB TTHA0145 210 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 55980269 Nonpathogen - hypothetical protein TTHA0300 1 None None None 55980741 Nonpathogen - hypothetical protein TTHA0772 1 None None None 55981912 Common - hypothetical protein TTHA1943 83 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 55980262 Nonpathogen - hypothetical protein TTHA0293 1 None None None 55981698 Common - putative methyltransferase TTHA1729 69 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 55981635 Common - 30S ribosomal protein S11 TTHA1666 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 55981858 Nonpathogen - hypothetical protein TTHA1889 2 None None None 55980141 Common - undecaprenol kinase TTHA0172 165 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 55980685 Common - molybdenum ABC transporter, permease protein TTHA0716 226 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 55980005 Nonpathogen - hypothetical protein TTHA0036 4 None None None 55980371 Nonpathogen - hypothetical protein TTHA0402 1 None None None 55981115 Common - electron transfer flavoprotein, alpha subunit TTHA1146 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 55981775 Common - MutM protein (formamidopyrimidine-DNA glycosylase) (Fpg) TTHA1806 179 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 55980624 Common - hypothetical protein TTHA0655 19 COG2345 COG2345, Predicted transcriptional regulator Transcription 55981341 Common - N-acetylmuramoyl-L-alanine amidase TTHA1372 177 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 55980387 Common rpmF 50S ribosomal protein L32 TTHA0418 86 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 55981703 Nonpathogen - hypothetical protein TTHA1734 2 COG3462 COG3462, Predicted membrane protein Function unknown 55981820 Nonpathogen - hypothetical protein TTHA1851 1 None None None 55981848 Common - ferripyochelin-binding protein TTHA1879 116 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 55980025 Common - ammonium transporter TTHA0056 193 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 55980947 Common - hypothetical protein TTHA0978 28 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 55981082 Common - L-lactate dehydrogenase TTHA1113 155 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 55980498 Nonpathogen - hypothetical protein TTHA0529 2 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 55980172 Common - hypothetical protein TTHA0203 66 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 55981642 Common rplO 50S ribosomal protein L15 TTHA1673 217 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 55981343 Common - pantothenate kinase TTHA1374 126 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 55981879 Common - probable homoaconitase small subunit (homoaconitate hydratase) TTHA1910 216 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 55980129 Nonpathogen - hypothetical protein TTHA0160 1 COG1341 COG1341, Predicted GTPase or GTP-binding protein General function prediction only 55980057 Common - NADH-quinone oxidoreductase chain 2 TTHA0088 157 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 55980248 Common - putative threonine dehydratase TTHA0279 191 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 55981297 Common - 5'-nucleotidase precursor TTHA1328 142 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 55980983 Common - hypothetical protein TTHA1014 37 COG1483 COG1483, Predicted ATPase (AAA+ superfamily) General function prediction only 55981189 Common - hypothetical protein TTHA1220 14 COG3156 PulK, Type II secretory pathway, component PulK Intracellular trafficking and secretion 55980023 Common - RNA methyltransferase TTHA0054 157 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 55980691 Common - histidinol dehydrogenase TTHA0722 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 55979996 Common - probable potassium channel, beta subunit (oxidoreductase) TTHA0027 203 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 55981734 Common - hypothetical protein TTHA1765 26 None None None 55981666 Common rpsL 30S ribosomal protein S12 TTHA1697 240 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 55980618 Common - putative O-antigen transporter TTHA0649 31 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 55980800 Common - polyA polymerase family protein TTHA0831 148 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 55981633 Common - DNA-directed RNA polymerase subunit alpha TTHA1664 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 55981334 Common - putative iron-sulfur protein TTHA1365 137 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 55981647 Common rpsH 30S ribosomal protein S8 TTHA1678 244 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 55980443 Common - acetoin utilization protein AcuB (acetoin dehydrogenase) TTHA0474 205 COG0517 COG0517, FOG: CBS domain General function prediction only 55980148 Nonpathogen - hypothetical protein TTHA0179 23 COG2266 COG2266, GTP:adenosylcobinamide-phosphate guanylyltransferase Coenzyme metabolism 55980226 Common - hypothetical protein TTHA0257 31 COG3872 COG3872, Predicted metal-dependent enzyme General function prediction only 55981285 Common - hypothetical protein TTHA1316 48 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 55980292 Common - hypothetical protein TTHA0323 67 COG1624 COG1624, Uncharacterized conserved protein Function unknown 55981456 Common - ATP-dependent Clp protease, ATP-binding subunit ClpB TTHA1487 227 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 55980815 Common - metallo-beta-lactamase family protein TTHA0846 11 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 55980433 Nonpathogen - hypothetical protein TTHA0464 1 None None None 55980774 Nonpathogen - hypothetical protein TTHA0805 1 None None None 55980835 Common - hypothetical protein TTHA0866 48 COG2319 COG2319, FOG: WD40 repeat General function prediction only 55981810 Common - putative dioxygenase ferredoxin subunit TTHA1841 89 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 55979973 Nonpathogen - hypothetical protein TTHA0004 1 None None None 55981270 Common - hypothetical protein TTHA1301 100 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 55980951 Common - bacterioferritin TTHA0982 105 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 55980198 Common - 2-oxoisovalerate dehydrogenase, E1 component alpha subunit TTHA0229 154 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 55980547 Common - uridine kinase TTHA0578 103 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 55981033 Common - diaminohydroxyphosphoriboxylaminopyrimidine deaminase + 5-amino-6-(5-phosphoribosylamino)uracil reductase (RibD) TTHA1064 230 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 55980864 Nonpathogen - universal stress protein family TTHA0895 4 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 55981442 Common - hypothetical protein TTHA1473 130 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 55981068 Common - sugar ABC transporter, ATP-binding protein TTHA1099 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 55981392 Common - cytochrome c-552 precursor TTHA1423 44 COG3258 COG3258, Cytochrome c Energy production and conversion 55981469 Common - phosphoenolpyruvate synthase TTHA1500 234 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 55980121 Common - tungsten-containing aldehyde:ferredoxin oxidoreductase TTHA0152 57 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 55980307 Common - hypothetical protein TTHA0338 72 COG1912 COG1912, Uncharacterized conserved protein Function unknown 55980012 Common - lipoprotein signal peptidase TTHA0043 8 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 55980657 Common - sugar ABC transporter, substrate-binding protein TTHA0688 78 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 55981369 Common - cytochrome complex Rieske iron-sulfur subunit TTHA1400 6 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 55981409 Common - excinuclease ABC subunit A (UvrA) TTHA1440 244 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 55981618 Common - nucleotidyltransferase TTHA1649 57 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 55980912 Nonpathogen - hypothetical protein TTHA0943 1 None None None 55981300 Common - branched-chain amino acid ABC transporter, permease protein TTHA1331 150 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 55980380 Common - alpha-aminoadipate aminotransferase TTHA0411 225 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 55980762 Common - hypothetical protein TTHA0793 241 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 55981829 Common - DNA polymerase III delta prime subunit TTHA1860 29 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 55981408 Nonpathogen - probable sugar aminotransferase TTHA1439 2 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 55980727 Common - hypothetical protein TTHA0758 93 COG1801 COG1801, Uncharacterized conserved protein Function unknown 55981063 Common trpA tryptophan synthase subunit alpha TTHA1094 216 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 55980588 Common - hypothetical protein TTHA0619 13 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 55981883 Common - homocitrate synthase TTHA1914 204 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 55980634 Common - N5,N10-methylenetetrahydromethanopterin reductase TTHA0665 60 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 55981671 Nonpathogen - hypothetical protein TTHA1702 1 None None None 55981867 Common - A/G-specific adenine glycosylase (MutY) TTHA1898 229 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 55980473 Common - glycolate oxidase subunit GlcE TTHA0504 65 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 55980812 Common - serine protein kinase TTHA0843 71 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 55981862 Common - S-layer protein precursor (P100 protein) TTHA1893 21 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 55981348 Common - competence protein PilM TTHA1379 79 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 55980902 Nonpathogen - hypothetical protein TTHA0933 1 COG1598 COG1598, Uncharacterized conserved protein Function unknown 55981042 Common rpmE 50S ribosomal protein L31 TTHA1073 160 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 55981020 Nonpathogen - hypothetical protein TTHA1051 1 None None None 55981580 Common - 5-formyltetrahydrofolate cyclo-ligase family protein TTHA1611 132 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 55980312 Common - folyl-polyglutamate synthetase TTHA0343 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 55980665 Nonpathogen - hypothetical protein TTHA0696 5 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 55980829 Common tsf elongation factor Ts TTHA0860 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 55980705 Nonpathogen - hypothetical protein TTHA0736 1 None None None 55980675 Common - cation-transporting ATPase TTHA0706 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 55981769 Common - hypothetical protein TTHA1800 5 COG2234 Iap, Predicted aminopeptidases General function prediction only 55981806 Nonpathogen - hypothetical protein TTHA1837 2 COG2976 COG2976, Uncharacterized protein conserved in bacteria Function unknown 55981400 Common - hypothetical protein TTHA1431 35 COG3360 COG3360, Uncharacterized conserved protein Function unknown 55980074 Common - hypothetical protein TTHA0105 26 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 55981508 Common - putative phage integrase/recombinase TTHA1539 214 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 55980647 Common - thiamine biosynthesis protein ThiC TTHA0678 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 55981526 Common - propionyl-CoA carboxylase, beta subunit TTHA1557 143 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 55980486 Nonpathogen - DedA family protein TTHA0517 1 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 55980424 Common - rrf2 family protein, transcriptional regulator TTHA0455 180 COG1959 COG1959, Predicted transcriptional regulator Transcription 55981263 Common - ribosomal subunit interface protein TTHA1294 170 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 55981530 Nonpathogen - probable DNA-directed RNA polymerase omega chain (RpoZ) TTHA1561 2 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 55981437 Common - glutamate synthase, large subunit TTHA1468 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 55980076 Nonpathogen - hypothetical protein TTHA0107 5 None None None 55981018 Common - hypothetical protein TTHA1049 67 COG1030 NfeD, Membrane-bound serine protease (ClpP class) Posttranslational modification, protein turnover, chaperones 55980668 Common infB translation initiation factor IF-2 TTHA0699 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 55981049 Nonpathogen - hypothetical protein TTHA1080 1 None None None 55980204 Common - hypothetical protein TTHA0235 58 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 55981896 Common - gamma-glutamyl kinase TTHA1927 189 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 55980173 Common - conserved hypothetical protein, integral membrane protein TTHA0204 29 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 55980440 Common - peptide ABC transporter, permease protein TTHA0471 218 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 55981245 Nonpathogen - V-type ATP synthase subunit E TTHA1276 1 COG1390 NtpE, Archaeal/vacuolar-type H+-ATPase subunit E Energy production and conversion 55980138 Nonpathogen - hypothetical protein TTHA0169 3 None None None 55981316 Common - endonuclease V TTHA1347 73 COG1515 Nfi, Deoxyinosine 3'endonuclease (endonuclease V) DNA replication, recombination, and repair 55980396 Common - hypothetical protein TTHA0427 19 COG2250 COG2250, Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN Function unknown 55981819 Nonpathogen - hypothetical protein TTHA1850 1 None None None 55980620 Nonpathogen - hypothetical protein TTHA0651 1 None None None 55980996 Common - DNA integration/recombination/invertion protein TTHA1027 36 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 55980717 Common - iron ABC transporter, ATP-binding protein TTHA0748 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 55980110 Nonpathogen - hypothetical protein TTHA0141 1 None None None 55980612 Common - putative glycosyltransferase TTHA0643 111 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 55980587 Common - 5-methyltetrahydrofolate homocysteine S-methyltransferase TTHA0618 180 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 55980995 Common - hypothetical protein TTHA1026 16 None None None 55980317 Nonpathogen - hypothetical protein TTHA0348 1 COG1950 COG1950, Predicted membrane protein Function unknown 55980043 Common - DNA topoisomerase IA TTHA0074 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 55981876 Common - lysine biosynthesis enzyme LysX TTHA1907 151 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 55981233 Common - putative zinc protease TTHA1264 192 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 55980090 Common - competence protein DprA (SMF protein (DNA processing chain A)) TTHA0121 208 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 55981726 Common - acetyl-lysine deacetylase TTHA1757 140 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 55981387 Common - putative cytochrome c TTHA1418 12 None None None 55980809 Common - probable thiol:disulfide interchange protein TTHA0840 161 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 55981239 Common - V-type ATP synthase, subunit (VTPJ-THERM) TTHA1270 14 None None None 55981869 Common - NH(3)-dependent NAD(+) synthetase TTHA1900 233 COG0171 NadE, NAD synthase Coenzyme metabolism 55981628 Nonpathogen - tetratricopeptide repeat family protein TTHA1659 4 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 55980449 Common - trehalose-phosphate synthase related protein TTHA0480 45 COG0380 OtsA, Trehalose-6-phosphate synthase Carbohydrate transport and metabolism 55980790 Common - hypothetical protein TTHA0821 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 55981589 Common - aminotransferase, class I TTHA1620 236 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 55981283 Common - UDP-N-acetylglucosamine 2-epimerase TTHA1314 150 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 55980346 Common - sugar ABC transporter, permease protein TTHA0377 144 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 55980884 Nonpathogen - hypothetical protein TTHA0915 1 None None None 55980414 Nonpathogen - ribonuclease P protein component TTHA0445 1 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 55980502 Common - probable ribosomal RNA small subunit methyltransferase TTHA0533 83 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 55981426 Common - S-adenosylmethionine decarboxylase proenzyme TTHA1457 62 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 55981003 Common - hypothetical protein TTHA1034 60 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 55980924 Common - mannosyl-3-phosphoglycerate phosphatase TTHA0955 29 COG3769 COG3769, Predicted hydrolase (HAD superfamily) General function prediction only 55981368 Common - tyrosyl-tRNA synthetase TTHA1399 244 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 55980286 Nonpathogen - hypothetical protein TTHA0317 4 None None None 55981464 Common - hypothetical protein TTHA1495 31 COG1714 COG1714, Predicted membrane protein/domain Function unknown 55981711 Common pyrE orotate phosphoribosyltransferase TTHA1742 139 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 55981802 Nonpathogen - ABC transporter, permease protein TTHA1833 14 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 55981375 Common - cytochrome c-type biogenesis protein, heme exporter protein TTHA1406 162 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 55980764 Common - hypothetical protein TTHA0795 94 COG2947 COG2947, Uncharacterized conserved protein Function unknown 55981021 Nonpathogen - hypothetical protein TTHA1052 2 COG4113 COG4113, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 55981193 Common - hypothetical protein TTHA1224 15 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 55980335 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B TTHA0366 213 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 55981933 Nonpathogen - hypothetical protein TTHA1964 1 None None None 55981774 Nonpathogen - hypothetical protein TTHA1805 1 COG3011 COG3011, Uncharacterized protein conserved in bacteria Function unknown 55981267 Common - methionyl-tRNA synthetase TTHA1298 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 55981836 Common - transposase TTHA1867 82 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 55980514 Common - aspartate-semialdehyde dehydrogenase TTHA0545 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 55980797 Nonpathogen - hypothetical protein TTHA0828 1 None None None 55980837 Common - chorismate mutase TTHA0868 39 COG4401 AroH, Chorismate mutase Amino acid transport and metabolism 55980064 Common - NADH-quinone oxidoreductase chain 12 TTHA0095 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 55980230 Common - probable phosphate ABC transporter, permease protein TTHA0261 236 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 55980120 Common - molybdopterin converting factor, subunit 1 (moaD) TTHA0151 43 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 55980787 Nonpathogen - hypothetical protein TTHA0818 1 None None None 55980242 Nonpathogen - hypothetical protein (transposase related protein) TTHA0273 1 None None None 55980753 Nonpathogen - hypothetical protein TTHA0784 5 None None None 55980578 Common - tRNA (adenine-N(1)-)-methyltransferase TTHA0609 59 COG2519 GCD14, tRNA(1-methyladenosine) methyltransferase and related methyltransferases Translation, ribosomal structure and biogenesis 55979971 Common - enolase (2-phosphoglycerate dehydratase) TTHA0002 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 55981554 Nonpathogen - hypothetical protein TTHA1585 1 None None None 55981477 Common - gamma-carboxymuconolactone decarboxylase TTHA1508 84 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 55980965 Common - succinate-semialdehyde dehydrogenase TTHA0996 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 55981849 Common - MutT/nudix family protein TTHA1880 79 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 55980086 Common - hypothetical protein TTHA0117 17 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 55979988 Nonpathogen - hypothetical protein TTHA0019 2 COG2105 COG2105, Uncharacterized conserved protein Function unknown 55981135 Nonpathogen - hypothetical protein TTHA1166 1 None None None 55981551 Common - 2-amino-3-ketobutyrate CoA ligase (glycine acetyltransferase) TTHA1582 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 55981486 Common - phosphoribosylformylglycinamidine synthetase I TTHA1517 232 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 55981393 Common - ABC transporter ATP-binding protein (CycB) TTHA1424 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 55979981 Common - conserved hypothetical protein, integral membrane protein TTHA0012 93 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 55980092 Common - transcriptional regulator, LysR family TTHA0123 182 COG0583 LysR, Transcriptional regulator Transcription 55981672 Common - sodium-alanine symporter family protein TTHA1703 112 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 55981276 Nonpathogen - hypothetical protein TTHA1307 1 None None None 55980103 Common - hypothetical protein TTHA0134 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 55981032 Common - riboflavin synthase subunit alpha TTHA1063 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 55981251 Nonpathogen - hypothetical protein TTHA1282 1 None None None 55981361 Common - Sir2 family protein TTHA1392 152 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 55981764 Nonpathogen - MutT/nudix family protein TTHA1795 1 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 55980627 Nonpathogen - hypothetical protein TTHA0658 1 None None None 55980758 Common - putative glutaryl-CoA dehydrogenase TTHA0789 159 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 55980659 Common - acetyl-CoA acetyltransferase TTHA0690 185 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 55980520 Common infC translation initiation factor IF-3 TTHA0551 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 55981519 Common - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase TTHA1550 63 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 55980710 Common - GTP-binding protein LepA TTHA0741 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 55980362 Nonpathogen - hypothetical protein TTHA0393 4 COG5652 COG5652, Predicted integral membrane protein Function unknown 55981499 Common - hypothetical protein TTHA1530 7 None None None 55981050 Common - phospho-N-acetylmuramoyl-pentapeptide- transferase TTHA1081 209 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 55981264 Common - cell-division ATP-binding protein FtsE TTHA1295 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 55981384 Common - sulfur oxidation protein SoxA TTHA1415 31 COG3258 COG3258, Cytochrome c Energy production and conversion 55981808 Common - SufB protein (membrane protein) TTHA1839 187 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 55981354 Common - shikimate kinase TTHA1385 197 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 55980145 Common - probable acetyltransferase TTHA0176 4 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 55981549 Common - transcriptional regulator, GntR family TTHA1580 134 COG1802 GntR, Transcriptional regulators Transcription 55980529 Nonpathogen - hypothetical protein TTHA0560 6 COG1550 COG1550, Uncharacterized protein conserved in bacteria Function unknown 55980191 Common - adenylosuccinate synthase TTHA0222 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 55981211 Common - cell division inhibitor MinE TTHA1242 32 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 55981492 Nonpathogen - hypothetical protein TTHA1523 1 None None None 55981592 Common - metallo-beta-lactamase superfamily protein TTHA1623 223 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 55980771 Common - hypothetical protein TTHA0802 115 COG2353 COG2353, Uncharacterized conserved protein Function unknown 55980866 Common - hypothetical protein TTHA0897 10 COG3809 COG3809, Uncharacterized protein conserved in bacteria Function unknown 55981091 Common - hypothetical protein TTHA1122 10 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 55980187 Common - enoyl-CoA hydratase TTHA0218 86 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 55980066 Common - NADH-quinone oxidoreductase chain 14 TTHA0097 185 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 55980308 Nonpathogen - hypothetical protein TTHA0339 1 COG3071 HemY, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 55980735 Common - ABC transporter, solute-binding protein TTHA0766 112 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 55981214 Nonpathogen - hypothetical protein TTHA1245 1 None None None 55980323 Common - ABC transporter, permease protein, MalFG family TTHA0354 132 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 55980353 Common - prolipoprotein diacylglyceryl transferase TTHA0384 199 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 55981290 Common - formyltetrahydrofolate deformylase TTHA1321 212 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 55980942 Common - transcriptional regulator, TetR family TTHA0973 82 COG1309 AcrR, Transcriptional regulator Transcription 55981414 Common - phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase TTHA1445 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 55981262 Nonpathogen - hypothetical protein TTHA1293 2 None None None 55980601 Nonpathogen - predicted nucleotidyltransferase TTHA0632 6 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 55980143 Common - alternative chaperone protein DnaJ TTHA0174 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 55981659 Common rplW 50S ribosomal protein L23 TTHA1690 150 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 55980880 Nonpathogen - hypothetical protein TTHA0911 1 None None None 55981826 Nonpathogen - hypothetical protein TTHA1857 1 None None None 55981654 Common rplP 50S ribosomal protein L16 TTHA1685 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 55980703 Common - hemolysin-related protein TTHA0734 218 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 55981009 Common - cation efflux system membrane protein TTHA1040 139 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 55980522 Common rplT 50S ribosomal protein L20 TTHA0553 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 55980669 Common - hypothetical protein TTHA0700 30 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 55980461 Nonpathogen - hypothetical protein TTHA0492 1 None None None 55980908 Common - pyruvate dehydrogenase (lipoamide) E1-alpha chain TTHA0939 155 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 55980435 Common - alcohol dehydrogenase TTHA0466 203 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 55980539 Common - putative oxidoreductase (glucose dehydrogenase) TTHA0570 123 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 55981043 Nonpathogen - hypothetical protein TTHA1074 1 None None None 55981680 Common - hypothetical protein TTHA1711 83 COG1355 COG1355, Predicted dioxygenase General function prediction only 55980447 Common - trehalose synthase TTHA0478 175 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 55980594 Common - hypothetical protein TTHA0625 81 COG1692 COG1692, Uncharacterized protein conserved in bacteria Function unknown 55981924 Common - 2-oxoacid--ferredoxin oxidoreductase, alpha chain TTHA1955 106 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 55980855 Common - UDP-galactopyranose mutase TTHA0886 54 COG0562 Glf, UDP-galactopyranose mutase Cell envelope biogenesis, outer membrane 55980089 Common era GTP-binding protein Era TTHA0120 227 COG1159 Era, GTPase General function prediction only 55980975 Common - hypothetical protein TTHA1006 168 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 55980632 Common - pyruvate phosphate dikinase TTHA0663 217 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 55981696 Common - hypothetical protein TTHA1727 6 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 55981503 Common - ribonuclease II family protein TTHA1534 189 COG0557 VacB, Exoribonuclease R Transcription 55981423 Common sdhA succinate dehydrogenase flavoprotein subunit TTHA1454 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 55981085 Common - hypothetical protein TTHA1116 15 None None None 55981451 Common - bacterioferritin TTHA1482 65 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 55980368 Nonpathogen - hypothetical protein TTHA0399 1 None None None 55980478 Common - N-acyl-L-amino acid amidohydrolase TTHA0509 190 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 55980170 Common - Mg(2+) chelatase family protein TTHA0201 189 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 55980021 Common - putative deacetylase TTHA0052 160 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 55981016 Nonpathogen - hypothetical protein TTHA1047 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 55981533 Common - putative methylated-DNA--protein-cysteine methyltransferase (Ogt) TTHA1564 202 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 55981566 Common - putative transporter TTHA1597 63 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 55981199 Common - 3-isopropylmalate dehydrogenase TTHA1230 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 55980309 Common - hypothetical protein TTHA0340 23 None None None 55980730 Common - iron-sulfur cluster biosynthesis protein SufE TTHA0761 20 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 55981454 Nonpathogen - hypothetical protein TTHA1485 5 COG1503 eRF1, Peptide chain release factor 1 (eRF1) Translation, ribosomal structure and biogenesis 55980694 Common - membrane-bound protein LytR TTHA0725 63 COG1316 LytR, Transcriptional regulator Transcription 55980934 Common - phenylacetic acid degradation protein PaaI TTHA0965 58 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 55980228 Common - phosphate ABC transporter, periplasmid phosphate-biniding protein TTHA0259 155 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 55981816 Nonpathogen - hypothetical protein TTHA1847 1 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 55980221 Common - metallo-beta-lactamase superfamily protein TTHA0252 147 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 55980582 Nonpathogen - hypothetical protein TTHA0613 1 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 55980699 Nonpathogen - hypothetical protein TTHA0730 5 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 55981762 Common - hypothetical protein TTHA1793 15 COG1694 MazG, Predicted pyrophosphatase General function prediction only 55980721 Common - beta-lactamase family protein TTHA0752 137 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 55980910 Common - ABC transporter ATP-binding protein TTHA0941 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 55980551 Common - aspartate aminotransferase, subgroup IV TTHA0582 153 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 55981402 Common - hypothetical protein TTHA1433 17 COG3294 COG3294, Uncharacterized conserved protein Function unknown 55981880 Common - probable homoaconitase large subunit (homoaconitate hydratase) TTHA1911 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 55981062 Nonpathogen - hypothetical protein TTHA1093 2 None None None 55980817 Nonpathogen recX recombination regulator RecX TTHA0848 1 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 55980297 Common - probable isochorismatase TTHA0328 163 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 55981371 Common - cytochrome c-type biogenesis protein TTHA1402 88 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 55981307 Common - ABC transporter permease protein TTHA1338 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 55981002 Common - 16S rRNA processing protein RimM TTHA1033 140 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 55981436 Common - hypothetical protein TTHA1467 89 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 55981885 Common - acyl-CoA dehydrogenase TTHA1916 163 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 55981803 Common - ABC transporter, ATP-binding protein TTHA1834 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 55981827 Common - probable oxidoreductase TTHA1858 49 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 55981399 Common - long-chain fatty acid--CoA ligase TTHA1430 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 55980014 Common - probable potassium uptake protein TrkA TTHA0045 23 COG3400 COG3400, Uncharacterized protein conserved in bacteria Function unknown 55980290 Common - polypeptide deformylase TTHA0321 212 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 55980615 Nonpathogen - hypothetical protein TTHA0646 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 55981758 Common - molybdenum cofactor biosynthesis protein C TTHA1789 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 55980216 Common rplK 50S ribosomal protein L11 TTHA0247 249 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 55981362 Common - hypothetical protein TTHA1393 219 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 55980352 Nonpathogen - putative thioredoxin TTHA0383 1 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 55981056 Nonpathogen - cell division protein FtsQ-related protein TTHA1087 2 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 55980343 Common - hypothetical protein TTHA0374 39 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 55981320 Common - peptidase, M20/M25/M40 family TTHA1351 15 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 55980151 Common - hypothetical protein TTHA0182 5 COG4113 COG4113, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 55981851 Common - hypothetical protein TTHA1882 147 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 55980401 Common - 'IMP dehydrogenase/GMP reductase TTHA0432 242 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 55981705 Common - iron-sulfur cluster biosynthesis protein IscU TTHA1736 183 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 55981346 Nonpathogen - hypothetical protein TTHA1377 3 None None None 55980796 Nonpathogen - outer membrane protein, OmpH-like TTHA0827 2 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 55981253 Common - serine/threonine protein kinase, putative TTHA1284 145 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 55981324 Common - DNA gyrase subunit A TTHA1355 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 55981899 Common - quinol-cytochrome c reductase, cytochrome b subunit TTHA1930 148 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 55980929 Common - 4-hydroxyphenylacetate-3-hydroxylase TTHA0960 50 COG2368 COG2368, Aromatic ring hydroxylase Secondary metabolites biosynthesis, transport, and catabolism 55980891 Nonpathogen - hypothetical protein TTHA0922 1 None None None 55981728 Nonpathogen - hypothetical protein TTHA1759 1 COG2427 COG2427, Uncharacterized conserved protein Function unknown 55981144 Common - hypothetical protein TTHA1175 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 55981336 Common - hypothetical protein TTHA1367 56 COG1556 COG1556, Uncharacterized conserved protein Function unknown 55980416 Common - branched-chain amino acid transporter ATP-binding protein TTHA0447 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 55979998 Common - hypothetical protein TTHA0029 6 None None None 55980136 Common - transcriptional regulator (TetR/AcrR family) TTHA0167 66 COG1309 AcrR, Transcriptional regulator Transcription 55980275 Common - queuine tRNA ribosyltransferase TTHA0306 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 55981594 Common - osmotically inducible protein OsmC TTHA1625 78 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 55980033 Nonpathogen - hypothetical protein TTHA0064 1 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 55981168 Common - ornithine carbamoyltransferase TTHA1199 239 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 55981101 Common - probable gliding protein mglA TTHA1132 23 COG2229 COG2229, Predicted GTPase General function prediction only 55980492 Common - glycine cleavage system T protein (probable aminomethyltransferase) TTHA0523 179 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 55980338 Common - oxidoreductase, short-chain dehydrogenase/reductase family TTHA0369 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 55980385 Common - malonyl CoA-[acyl carrier protein] transacylase TTHA0416 208 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 55981795 Nonpathogen - hypothetical protein TTHA1826 1 None None None 55980625 Common prmA ribosomal protein L11 methyltransferase TTHA0656 188 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 55980003 Nonpathogen - hypothetical protein TTHA0034 2 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 55980989 Common - hypothetical protein TTHA1020 220 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 55980687 Common - uracil-DNA glycosylase TTHA0718 158 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 55980645 Common thiG thiazole synthase TTHA0676 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 55981834 Common - serine protease precursor TTHA1865 124 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 55980637 Nonpathogen - hypothetical protein TTHA0668 1 COG0730 COG0730, Predicted permeases General function prediction only 55981118 Common - uracil-DNA glycosylase TTHA1149 116 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 55981172 Common - hypothetical protein TTHA1203 170 COG0344 COG0344, Predicted membrane protein Function unknown 55980239 Common - carboxypeptidase TTHA0270 82 COG2317 COG2317, Zn-dependent carboxypeptidase Amino acid transport and metabolism 55980517 Nonpathogen - hypothetical protein TTHA0548 1 None None None 55980803 Common - endonuclease IV TTHA0834 99 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 55980124 Nonpathogen - hypothetical protein TTHA0155 1 None None None 55980107 Common - serine/threonine protein kinase TTHA0138 184 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 55981152 Common - penicillin-binding protein 1B TTHA1183 203 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 55981130 Common - hypothetical protein TTHA1161 111 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 55981644 Common rpsE 30S ribosomal protein S5 TTHA1675 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 55980303 Common - hypothetical protein TTHA0334 58 COG1993 COG1993, Uncharacterized conserved protein Function unknown 55981123 Nonpathogen - hypothetical protein TTHA1154 1 None None None 55980608 Common - predicted nucleotidyltransferase TTHA0639 7 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 55981785 Common - rod shape-determining protein MreB TTHA1816 226 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 55980162 Common - hypothetical protein TTHA0193 12 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 55980544 Nonpathogen - hypothetical protein TTHA0575 2 None None None 55981602 Common - peptide ABC transporter permease protein TTHA1633 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 55980844 Common - seryl-tRNA synthetase TTHA0875 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 55981149 Common - low molecular weight phosphotyrosine protein phosphatase TTHA1180 141 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 55981093 Common - acetyl-CoA carboxylase, biotin carboxyl carrier protein TTHA1124 204 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 55981582 Common - adenine phosphoribosyltransferase TTHA1613 7 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 55981846 Common - sugar ABC transporter, periplasmic sugar-binding protein TTHA1877 110 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 55981736 Common - acetyl-CoA carboxylase carboxyl transferase, alpha subunit (AccA) TTHA1767 206 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 55980781 Common - phosphoribosylamine--glycine ligase TTHA0812 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 55981678 Nonpathogen - hypothetical protein TTHA1709 1 COG4715 COG4715, Uncharacterized conserved protein Function unknown 55980484 Common - hypothetical protein TTHA0515 32 COG3329 COG3329, Predicted permease General function prediction only 55981721 Common - hypothetical protein TTHA1752 16 None None None 55980874 Common - glyceraldehyde 3-phosphate dehydrogenase (GAPDH) TTHA0905 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 55981663 Common - elongation factor Tu TTHA1694 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 55981753 Nonpathogen secG preprotein translocase subunit SecG TTHA1784 1 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 55980556 Common - branched-chain amino acid ABC transporter, ATP-binding protein TTHA0587 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 55981357 Common - holo-[acyl carrier protein] synthase TTHA1388 89 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 55980981 Nonpathogen - hypothetical protein TTHA1012 2 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 55981208 Common - spermidine/putrescine ABC transporter, permease protein TTHA1239 189 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 55981258 Common - exonuclease SbcD TTHA1289 117 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 55980882 Nonpathogen - hypothetical protein TTHA0913 1 None None None 55980792 Common - hypothetical membrane protein TTHA0823 89 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 55980629 Common - oxidoreductase, short-chain dehydrogenase/reductase family TTHA0660 235 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 55980712 Common - glycosyltransferase related protein TTHA0743 99 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 55980969 Common - hypothetical protein TTHA1000 5 COG3295 COG3295, Uncharacterized protein conserved in bacteria Function unknown 55980412 Common - hypothetical protein TTHA0443 211 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 55981103 Common - ba3-type cytochrome c oxidase polypeptide II TTHA1134 87 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 55980825 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase TTHA0856 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 55981281 Common - uracil phosphoribosyltransferase TTHA1312 163 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 55981073 Common - prephenate dehydratase TTHA1104 213 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 55980512 Common - glycyl-tRNA synthetase TTHA0543 86 COG0423 GRS1, Glycyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 55980062 Nonpathogen - NADH-quinone oxidoreductase chain 10 TTHA0093 1 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 55980189 Common - hypoxanthine-guanine phosphoribosyltransferase TTHA0220 150 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 55980799 Nonpathogen - hypothetical protein TTHA0830 1 None None None 55980566 Common - hypothetical protein TTHA0597 26 COG3044 COG3044, Predicted ATPase of the ABC class General function prediction only 55981799 Nonpathogen - hypothetical protein TTHA1830 1 None None None 55981574 Common - probable acylamino-acid-releasing enzyme TTHA1605 109 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 55981539 Common - deoxyhypusine synthase-like protein TTHA1570 63 COG1899 DYS1, Deoxyhypusine synthase Posttranslational modification, protein turnover, chaperones 55980533 Nonpathogen - cell division initiation protein DivIVA TTHA0564 2 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 55981359 Common - acyltransferase family protein TTHA1390 35 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 55980838 Common - LmbE-related protein TTHA0869 30 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 55980785 Nonpathogen - hypothetical protein TTHA0816 1 None None None 55981059 Common - Holliday junction resolvase RuvC TTHA1090 197 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 55981243 Nonpathogen - V-type ATP synthase subunit F TTHA1274 5 COG1436 NtpG, Archaeal/vacuolar-type H+-ATPase subunit F Energy production and conversion 55980576 Common - biotin synthase (biotin synthetase) TTHA0607 176 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 55981556 Common - D-alanine--D-alanine ligase TTHA1587 212 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 55980394 Common - NADH oxidase (H2O2-forming) TTHA0425 83 COG0778 NfnB, Nitroreductase Energy production and conversion 55981279 Common - hypothetical protein TTHA1310 32 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 55981187 Nonpathogen - probable prepilin-like protein TTHA1218 1 COG4967 PilV, Tfp pilus assembly protein PilV Cell motility and secretion / Intracellular trafficking and secretion 55981817 Nonpathogen - hypothetical protein TTHA1848 1 COG4907 COG4907, Predicted membrane protein Function unknown 55980466 Common - oxygen-independent coproporphyrinogen III oxidase TTHA0497 211 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 55979979 Nonpathogen - hypothetical protein TTHA0010 1 None None None 55981510 Nonpathogen - hypothetical protein TTHA1541 1 None None None 55980319 Nonpathogen - hypothetical protein TTHA0350 2 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 55981344 Nonpathogen - hypothetical protein TTHA1375 1 None None None 55981235 Common - DNA helicase RecG TTHA1266 214 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 55981790 Nonpathogen - hypothetical protein TTHA1821 12 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 55981072 Common - FemA-related protein TTHA1103 23 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 55980713 Nonpathogen - hypothetical protein TTHA0744 1 None None None 55980622 Nonpathogen - hypothetical protein TTHA0653 1 None None None 55980993 Nonpathogen - hypothetical protein TTHA1024 1 None None None 55980180 Common - lipoprotein releasing system transmembrane protein TTHA0211 28 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 55980719 Common - 3-oxoacyl-[acyl carrier protein] reductase TTHA0750 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 55980581 Common carB carbamoyl phosphate synthase large subunit TTHA0612 236 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 55981842 Nonpathogen - hypothetical protein TTHA1873 1 None None None 55981180 Common - ketol-acid reductoisomerase TTHA1211 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 55980218 Nonpathogen secE preprotein translocase subunit SecE TTHA0249 7 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 55980206 Common - 3-hydroxyisobutyrate dehydrogenase TTHA0237 162 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 55981389 Common - sulfur oxidation protein SoxZ TTHA1420 34 None None None 55980894 Common - poly(A) polymerase family protein TTHA0925 61 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 55981342 Common - hypothetical protein TTHA1373 84 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 55981626 Common - redox-sensing transcriptional repressor Rex TTHA1657 56 COG2344 COG2344, AT-rich DNA-binding protein General function prediction only 55981713 Common - hypothetical protein TTHA1744 27 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 55981162 Nonpathogen - hypothetical protein TTHA1193 5 COG2322 COG2322, Predicted membrane protein Function unknown 55981421 Common aspC aspartyl-tRNA synthetase TTHA1452 249 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 55981800 Common - alanyl-tRNA synthetase TTHA1831 248 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 55980355 Common - Sec-independent protein translocase protein TatA TTHA0386 27 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 55980868 Common - chromosome segregation SMC protein TTHA0899 168 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 55980873 Nonpathogen - biotin biosynthesis protein BioY TTHA0904 14 COG1268 BioY, Uncharacterized conserved protein General function prediction only 55980743 Nonpathogen - hypothetical protein TTHA0774 1 None None None 55981030 Common - hypothetical protein TTHA1061 82 COG2425 COG2425, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 55980483 Common - phosphoribosylaminoimidazole carboxylase catalytic subunit TTHA0514 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 55981052 Common - cell division protein, FtsW/RodA/SpoVE family TTHA1083 27 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 55981751 Common rpmA 50S ribosomal protein L27 TTHA1782 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 55981938 Common - chromosome partitioning protein, ParB family TTHA1969 189 COG1475 Spo0J, Predicted transcriptional regulators Transcription 55980922 Common - hypothetical protein TTHA0953 16 COG1510 COG1510, Predicted transcriptional regulators Transcription 55980458 Common - homoserine dehydrogenase TTHA0489 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 55981494 Common - DNA repair protein RecN TTHA1525 195 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 55981540 Nonpathogen - hypothetical protein TTHA1571 1 COG4723 COG4723, Phage-related protein, tail component Function unknown 55980328 Common - cold shock protein TTHA0359 182 COG1278 CspC, Cold shock proteins Transcription 55981590 Common - heat shock protein, class I TTHA1621 172 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 55980769 Common - 3-deoxy-7-phosphoheptulonate synthase TTHA0800 186 COG2876 AroA, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 55981470 Common - putative hemolysin TTHA1501 99 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 55980565 Common - ABC transporter solute-binding protein TTHA0596 176 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 55980953 Common - quinolinate synthetase TTHA0984 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 55981443 Common - hypothetical protein TTHA1474 72 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 55981292 Common - DNA mismatch repair protein MutL TTHA1323 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 55980451 Common - hypothetical protein TTHA0482 43 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 55980364 Nonpathogen - hypothetical protein TTHA0395 1 None None None 55980733 Common - hypothetical protein TTHA0764 7 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 55981607 Common - hypothetical protein TTHA1638 6 COG0400 COG0400, Predicted esterase General function prediction only 55980088 Common - putative acetyltransferase TTHA0119 206 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 55981905 Common - glycerol-3-phosphate ABC transporter, periplasmic glycerol-3-phosphate-binding protein TTHA1936 107 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 55980384 Common - 3-oxoacyl-[acyl carrier protein] reductase TTHA0415 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 55981916 Common - MutT/nudix family protein TTHA1947 12 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 55981225 Common - hypothetical protein TTHA1256 61 COG0393 COG0393, Uncharacterized conserved protein Function unknown 55981195 Nonpathogen - hypothetical protein TTHA1226 1 COG1354 COG1354, Uncharacterized conserved protein Function unknown 55981561 Common - sensor histidine kinase TTHA1592 19 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 55980831 Common - 4-aminobutyrate aminotransferase TTHA0862 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 55981475 Common hemA glutamyl-tRNA reductase TTHA1506 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 55979986 Nonpathogen - probable tetratricopeptide repeat family protein TTHA0017 1 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 55980071 Nonpathogen - hypothetical protein TTHA0102 1 None None None 55981514 Nonpathogen - hypothetical protein TTHA1545 1 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 55980152 Nonpathogen - 5-formyltetrahydrofolate cyclo-ligase TTHA0183 19 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 55981926 Nonpathogen - hypothetical protein TTHA1957 2 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 55981743 Common - pili retraction protein PilT TTHA1774 209 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 55981882 Common - hypothetical protein TTHA1913 11 COG1724 COG1724, Predicted periplasmic or secreted lipoprotein Cell motility and secretion 55981417 Common - 4-hydroxybutyrate CoA-transferase TTHA1448 101 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 55980105 Common - LAO/AO transport system kinase TTHA0136 99 COG1703 ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family Amino acid transport and metabolism 55981870 Common - carbon-nitrogen hydrolase family protein TTHA1901 124 COG0388 COG0388, Predicted amidohydrolase General function prediction only 55980963 Nonpathogen - hypothetical protein TTHA0994 1 None None None 55981564 Common - protein serine/threonine phosphatase TTHA1595 115 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 55980811 Common - hypothetical protein TTHA0842 71 COG2718 COG2718, Uncharacterized conserved protein Function unknown 55980650 Nonpathogen - hypothetical protein TTHA0681 2 None None None 55980508 Nonpathogen - hypothetical protein TTHA0539 11 COG1568 COG1568, Predicted methyltransferases General function prediction only 55981446 Common - hypothetical protein TTHA1477 22 COG0490 COG0490, Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels Inorganic ion transport and metabolism 55980696 Common - hypothetical protein TTHA0727 8 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 55981776 Common - ABC transporter, permease protein TTHA1807 49 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 55980109 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase TTHA0140 209 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 55981903 Nonpathogen - hypothetical protein TTHA1934 3 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 55981611 Common - S-adenosylmethionine synthetase TTHA1642 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 55980420 Common - probable branched-chain amino acid ABC transporter, amno acid binding protein TTHA0451 79 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 55980670 Common nusA transcription elongation factor NusA TTHA0701 222 COG0195 NusA, Transcription elongation factor Transcription 55981415 Common glpX fructose 1,6-bisphosphatase II TTHA1446 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 55981106 Common - major facilitator superfamily transporter TTHA1137 51 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 55980270 Nonpathogen - hypothetical protein TTHA0301 1 None None None 55981814 Nonpathogen - trp operon leader peptide TTHA1845 1 None None None 55980429 Common - MutT/nudix family protein TTHA0460 5 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 55981060 Common - hypothetical protein TTHA1091 33 COG1839 COG1839, Uncharacterized conserved protein Function unknown 55980494 Common - glycine dehydrogenase subunit 1 TTHA0525 172 COG0403 GcvP, Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain Amino acid transport and metabolism 55981397 Nonpathogen - putative phosphoglucomutase/phosphomannomutase TTHA1428 4 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 55980341 Common - hypothetical protein TTHA0372 116 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 55980059 Common - NADH-quinone oxidoreductase chain 3 TTHA0090 195 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 55980778 Common - probable 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase TTHA0809 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 55980530 Common - outer membrane protein TTHA0561 85 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 55980723 Common - transcriptional repressor TTHA0754 114 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 55981531 Common - guanylate kinase (GMP kinase) TTHA1562 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 55980277 Common - uracil permease [C-terminal] TTHA0308 115 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 55980409 Nonpathogen - hypothetical protein TTHA0440 2 COG4372 COG4372, Uncharacterized protein conserved in bacteria with the myosin-like domain Function unknown 55980542 Common - glutamyl-tRNA(Gln) amidotransferase subunit A TTHA0573 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 55981781 Common - DNA-directed RNA polymerase beta' chain (RpoC) TTHA1812 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 55980256 Common - 2-oxoglutarate dehydrogenase E3 component (dihydrolipoamide dehydrogenase) TTHA0287 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 55981314 Common - putative mannose-6-phosphate isomerase TTHA1345 47 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 55980558 Common - branched-chain amino acid ABC transporter permease protein TTHA0589 127 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 55981404 Common - purine nucleoside phosphorylase TTHA1435 89 COG0813 DeoD, Purine-nucleoside phosphorylase Nucleotide transport and metabolism 55981309 Common - folyl-polyglutamate synthetase TTHA1340 213 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 55980471 Nonpathogen - hypothetical protein TTHA0502 1 COG4423 COG4423, Uncharacterized protein conserved in bacteria Function unknown 55980001 Nonpathogen - hypothetical protein TTHA0032 4 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 55981364 Nonpathogen - hypothetical protein TTHA1395 4 None None None 55981516 Common - putative peptidase TTHA1547 93 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 55981756 Nonpathogen - hypothetical protein TTHA1787 1 None None None 55980501 Common - RNA polymerase pricipal sigma factor (RpoD) TTHA0532 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 55981000 Common rplS 50S ribosomal protein L19 TTHA1031 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 55980768 Common - prephenate dehydrogenase TTHA0799 152 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 55981748 Common - metal dependent phosphohydrolase (HD domain protein) TTHA1779 28 COG1713 COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism Coenzyme metabolism 55980223 Nonpathogen - hypothetical protein TTHA0254 1 None None None 55981260 Nonpathogen - putative membrane protein [C-terminal] TTHA1291 2 COG5438 COG5438, Predicted multitransmembrane protein Function unknown 55980630 Nonpathogen - hypothetical protein TTHA0661 2 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 55981095 Nonpathogen - hypothetical protein TTHA1126 19 None None None 55981433 Common rpsI 30S ribosomal protein S9 TTHA1464 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 55981686 Common - guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (ppGpp synthase) TTHA1717 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 55980667 Nonpathogen - hypothetical protein TTHA0698 1 None None None 55980510 Common - DNA repair protein RadA TTHA0541 201 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 55980700 Common - hypothetical protein TTHA0731 10 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 55980701 Nonpathogen - hypothetical protein TTHA0732 1 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 55981501 Common - oligoendopeptidase F TTHA1532 87 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 55981023 Common - DNA polymerase I TTHA1054 221 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 55981405 Common - ABC-type transporter, ATP-binding protein TTHA1436 220 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 55980179 Common rplL 50S ribosomal protein L7/L12 TTHA0210 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 55979991 Common - glucose-1-phosphate adenylyltransferase TTHA0022 186 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 55981146 Common - indigoidine synthase A like protein TTHA1177 49 COG2313 IndA, Uncharacterized enzyme involved in pigment biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 55980456 Common - hypothetical protein TTHA0487 37 COG3744 COG3744, Uncharacterized protein conserved in bacteria Function unknown 55979985 Common - tRNA-dihydrouridine synthase A TTHA0016 210 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 55981274 Common - molybdopterin-guanine dinucleotide biosynthesis protein A TTHA1305 108 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 55980906 Common - hypothetical protein TTHA0937 20 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 55981158 Common - rod shape-determining protein MreC TTHA1189 25 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 55981529 Common - DNA/pantothenate metabolism flavoprotein TTHA1560 228 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 55981931 Common pfkA 6-phosphofructokinase TTHA1962 160 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 55981655 Common rpsC 30S ribosomal protein S3 TTHA1686 248 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 55981038 Common - cell division protein FtsX TTHA1069 30 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 55981863 Nonpathogen - hypothetical protein TTHA1894 1 None None None 55981057 Common - cell division protein FtsA TTHA1088 198 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 55981014 Common - hypothetical protein TTHA1045 49 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 55981045 Common - hypothetical protein TTHA1076 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 55981466 Nonpathogen - hypothetical protein TTHA1497 5 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 55981087 Nonpathogen - hypothetical protein TTHA1118 1 None None None 55980445 Nonpathogen - hypothetical protein TTHA0476 2 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 55980940 Nonpathogen - phenylacetic acid degradation protein PaaB TTHA0971 2 COG3460 COG3460, Uncharacterized enzyme of phenylacetate metabolism Secondary metabolites biosynthesis, transport, and catabolism 55980956 Common - beta-ketoadipyl CoA thiolase TTHA0987 187 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 55980755 Common - glycerate dehydrogenase/glyoxylate reductase TTHA0786 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 55981111 Common - response regulator receiver domain protein TTHA1142 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 55980211 Common rplI 50S ribosomal protein L9 TTHA0242 216 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 55981667 Common - carboxypeptidase G2 TTHA1698 91 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 55981150 Common - sensor histidine kinase TTHA1181 151 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 55980842 Common - hypothetical protein TTHA0873 14 COG3375 COG3375, Uncharacterized conserved protein Function unknown 55980313 Common - ferric uptake regulatory protein TTHA0344 132 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 55980476 Common - transcriptional regulator TTHA0507 124 COG1414 IclR, Transcriptional regulator Transcription 55980976 Common - ABC transporter, ATP-binding protein TTHA1007 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 55980919 Common - DegV family protein TTHA0950 16 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 55981632 Common rplQ 50S ribosomal protein L17 TTHA1663 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 55981786 Common - hypothetical protein TTHA1817 76 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 55980680 Common aspS aspartyl-tRNA synthetase TTHA0711 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 55980932 Common - ABC tranpsorter ATP binding protein related protein TTHA0963 50 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 55980253 Common - argininosuccinate synthetase TTHA0284 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 55981707 Common - probable hydrolase TTHA1738 117 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 55981311 Common - ABC transporter, ATP-binding protein TTHA1342 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 55981170 Common - hypothetical protein TTHA1201 48 COG2361 COG2361, Uncharacterized conserved protein Function unknown 55981650 Common rplX 50S ribosomal protein L24 TTHA1681 210 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 55980805 Common - rhodanese-like domain protein TTHA0836 197 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 55980896 Nonpathogen - hypothetical protein TTHA0927 1 COG0344 COG0344, Predicted membrane protein Function unknown 55980660 Common - Type II 3-hydroxyacyl-CoA dehydrogenase TTHA0691 231 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 55981738 Common - hypothetical protein TTHA1769 60 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 55981661 Common rplC 50S ribosomal protein L3 TTHA1692 235 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 55981114 Common - electron transfer flavoprotein, beta subunit TTHA1145 146 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 55980237 Common - hypothetical protein TTHA0268 12 None None None 55980009 Common - FAD/FMN-containing dehydrogenase TTHA0040 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 55980052 Common ksgA dimethyladenosine transferase TTHA0083 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 55980028 Common - molybdenum cofactor biosynthesis protein D/E TTHA0059 158 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 55981700 Nonpathogen - hypothetical protein TTHA1731 6 None None None 55981676 Common - sugar fermentation stimulation protein family protein TTHA1707 44 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 55980613 Nonpathogen - hypothetical protein TTHA0644 4 None None None 55980987 Common - transposase TTHA1018 82 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 55980403 Nonpathogen - hypothetical protein TTHA0434 1 None None None 55981322 Common - probable RNA methyltransferase TTHA1353 197 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 55980244 Common - RNA 2'-O ribose methyltransferase TTHA0275 200 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 161986605 Common - O-sialoglycoprotein endopeptidase TTHA1252 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 55981797 Common - hypothetical protein TTHA1828 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 55980097 Common - ATP phosphoribosyltransferase TTHA0128 210 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 55980568 Common - protoporphyrinogen oxidase (HemG) TTHA0599 58 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 55980431 Nonpathogen - hypothetical protein TTHA0462 6 None None None 55981181 Common - acetolactate synthase, small subunit (ilvN) TTHA1212 193 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 55980031 Common - alanine racemase TTHA0062 199 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 55981205 Common - spermidine/putrescine ABC transporter, periplasmic spermidine/putrescine-binding protein TTHA1236 30 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 55980039 Common - ABC transporter permease protein TTHA0070 64 COG4662 TupA, ABC-type tungstate transport system, periplasmic component Coenzyme metabolism 55981007 Common - methylmalonyl-CoA mutase, alpha subunit, chain B TTHA1038 114 COG2185 Sbm, Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding) Lipid metabolism 55981840 Nonpathogen - hypothetical protein TTHA1871 5 None None None 55980249 Common - carbamoyl phosphate synthase small subunit TTHA0280 233 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 55981338 Common - phospholipase domain protein TTHA1369 147 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 55980406 Nonpathogen - hypothetical protein TTHA0437 1 None None None 55980374 Nonpathogen - hypothetical protein TTHA0405 1 None None None 55981331 Common - response regulator TTHA1362 213 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 55980610 Nonpathogen - hypothetical protein TTHA0641 7 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 55980689 Nonpathogen - hypothetical protein TTHA0720 1 COG3008 PqiB, Paraquat-inducible protein B General function prediction only 55980331 Common - hypothetical protein TTHA0362 176 COG1496 COG1496, Uncharacterized conserved protein Function unknown 55980927 Common - 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase TTHA0958 180 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 55981125 Common - O-acetylhomoserine (thiol)-lyase/O-acetylserine (thiol)-lyase TTHA1156 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 55981137 Nonpathogen - hypothetical protein TTHA1168 1 None None None 55980861 Common - acyl-CoA dehydrogenase TTHA0892 164 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 55981730 Common - hypothetical protein TTHA1761 27 COG3258 COG3258, Cytochrome c Energy production and conversion 55980135 Nonpathogen - hypothetical protein TTHA0166 1 COG4242 CphB, Cyanophycinase and related exopeptidases Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism 55980265 Common - RNA methyltransferase, TrmH family TTHA0296 213 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 55980233 Common - RecF protein TTHA0264 149 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 55981132 Nonpathogen - hypothetical protein TTHA1163 1 None None None 55981277 Common - hypothetical protein TTHA1308 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 55981694 Common - hypothetical protein TTHA1725 8 None None None 55980746 Common - hypothetical protein TTHA0777 4 None None None 55981639 Common - methionine aminopeptidase TTHA1670 249 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 55980643 Common - thiamin-phosphate pyrophosphorylase TTHA0674 204 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism