Thermus thermophilus HB27, complete genome NC_005835 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 46199838 Common - hypothetical protein TTC1536 130 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 46200154 Common - bacterial peptide chain release factor 2 (RF-2) TTC1852 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 46199811 Common - putative DNA polymerase III subunit TTC1509 29 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 46199553 Common - hypothetical protein TTC1251 77 COG1259 COG1259, Uncharacterized conserved protein Function unknown 46199345 Common - ABC transporter ATP-binding protein TTC1043 240 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 46199818 Common - threonyl-tRNA synthetase TTC1516 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 46200027 Common pstC phosphate transport system permease protein pstC TTC1725 225 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 46200086 Common - hypothetical protein TTC1784 4 COG3177 COG3177, Uncharacterized conserved protein Function unknown 46199897 Common - phenylalanyl-tRNA synthetase beta chain TTC1595 211 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 46198688 Nonpathogen - hypothetical protein TTC0380 1 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 46200280 Common - two-component response regulator TTC1978 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 46200071 Common - tRNA pseudouridine 55 synthase TTC1769 216 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 46199898 Nonpathogen - hypothetical protein TTC1596 1 None None None 46199529 Nonpathogen - hypothetical protein TTC1227 1 None None None 46200236 Nonpathogen - tungstate transport ATP-binding protein TTC1934 15 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 46199361 Common cycB cycB TTC1059 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 46199489 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein TTC1187 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 46199124 Common - putative RNA methyltransferase TTC0818 156 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 46199210 Common - V-type ATP synthase subunit B TTC0906 247 COG1156 NtpB, Archaeal/vacuolar-type H+-ATPase subunit B Energy production and conversion 46199869 Common - menaquinol-cytochrome C reductase cytochrome B subunit TTC1567 148 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 46198461 Nonpathogen - hypothetical membrane spanning protein TTC0153 1 None None None 46199540 Nonpathogen - hypothetical protein TTC1238 2 None None None 46198596 Common - UDP-N-acetyl-D-mannosamine 6-dehydrogenase TTC0288 207 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 46200031 Common - aminopeptidase A/I TTC1729 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 46200123 Common - hypothetical conserved membrane spanning protein TTC1821 10 COG2389 COG2389, Uncharacterized metal-binding protein General function prediction only 46199802 Nonpathogen - hypothetical protein TTC1500 1 None None None 46200048 Common - lipoate-protein ligase B TTC1746 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 46200052 Common - methyltransferase TTC1750 5 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 46199379 Common - tRNA (uracil-5-)-methyltransferase Gid TTC1077 123 COG1206 Gid, NAD(FAD)-utilizing enzyme possibly involved in translation Translation, ribosomal structure and biogenesis 46198893 Common degV degV protein TTC0585 51 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 46199638 Nonpathogen - hypothetical protein TTC1336 2 None None None 46198731 Nonpathogen - hypothetical protein TTC0423 2 None None None 46199857 Common - thioredoxin reductase TTC1555 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 46199301 Common - hypothetical protein TTC0999 21 COG4127 COG4127, Uncharacterized conserved protein Function unknown 46198707 Nonpathogen - hypothetical protein TTC0399 1 None None None 46198585 Nonpathogen - hypothetical protein TTC0277 5 None None None 46198483 Common - glycyl-tRNA synthetase TTC0175 86 COG0423 GRS1, Glycyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 46199598 Common - 5-methylcytosine-specific restriction enzyme A TTC1296 100 COG1403 McrA, Restriction endonuclease Defense mechanisms 46199258 Common - protease Do TTC0956 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 46198674 Common - uracil-DNA glycosylase TTC0366 158 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 46199873 Nonpathogen - hypothetical protein TTC1571 29 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 46200036 Common - elongation factor Tu TTC1734 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 46199760 Nonpathogen - hypothetical protein TTC1458 1 None None None 46198963 Nonpathogen - hypothetical protein TTC0655 1 None None None 46198578 Common - probable nucleotidyltransferase TTC0270 23 None None None 46199572 Common dppB dipeptide transport system permease protein dppB TTC1270 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 46199917 Nonpathogen - hypothetical protein TTC1615 2 None None None 46198466 Common - probable two-component sensor TTC0158 140 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 46198976 Common - two-component response regulator TTC0668 191 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 46198643 Common livG branched-chain amino acid transport ATP-binding protein livG TTC0335 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 46198729 Common - ABC transporter substrate-binding protein (taurine) TTC0421 78 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 46198874 Nonpathogen - hypothetical protein TTC0566 1 COG0517 COG0517, FOG: CBS domain General function prediction only 46198720 Nonpathogen - L-ribulose-phosphate 4-epimerase TTC0412 6 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 46199592 Common - nucleoside-triphosphatase TTC1290 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 46198635 Common - glucose transport system permease protein TTC0327 133 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 46198626 Common - putative oxidoreductase TTC0318 13 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 46199588 Common malG maltose transport system permease protein malG TTC1286 143 COG3833 MalG, ABC-type maltose transport systems, permease component Carbohydrate transport and metabolism 46198602 Nonpathogen - hypothetical protein TTC0294 1 None None None 46199959 Common - putative ATP/GTP-binding integral membrane protein TTC1657 17 COG1485 COG1485, Predicted ATPase General function prediction only 46200270 Nonpathogen - probable macrolide-efflux transmembrane protein TTC1968 12 None None None 46198396 Common - 3-phosphoshikimate 1-carboxyvinyltransferase TTC0088 216 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 46199531 Common - probable two-component response regulator TTC1229 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 46199903 Nonpathogen - hypothetical protein TTC1601 1 None None None 46199368 Common - hypothetical protein TTC1066 35 COG3360 COG3360, Uncharacterized conserved protein Function unknown 46198443 Common - probable coenzyme F390 synthetase/phenylaceate-CoA ligase TTC0135 111 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 46199952 Common - sulfite dehydrogenase TTC1650 100 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 46199496 Common - transcriptional repressor TTC1194 81 COG1438 ArgR, Arginine repressor Transcription 46200097 Common - dihydropteroate synthase TTC1795 219 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 46199723 Common - nicotinate-nucleotide adenylyltransferase TTC1421 187 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 46198691 Common - cytidine deaminase TTC0383 112 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 46200104 Common - branched-chain alpha-keto acid dehydrogenase subunit E2 TTC1802 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 46198676 Nonpathogen - hypothetical protein TTC0368 1 COG3008 PqiB, Paraquat-inducible protein B General function prediction only 46198952 Common - putative two-component system sensor kinase TTC0644 199 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 46198812 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase TTC0504 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 46199998 Common ruvA holliday junction DNA helicase ruvA TTC1696 183 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 46198320 Common - probable tungsten-containing aldehyde ferredoxin oxidoreductase TTC0012 57 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 46200213 Nonpathogen - NADH-quinone oxidoreductase chain J TTC1911 1 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 46199937 Nonpathogen - hypothetical protein TTC1635 1 COG1950 COG1950, Predicted membrane protein Function unknown 46199886 Nonpathogen - putative CoA pyrophosphatase/phosphohydrolase TTC1584 5 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 46198971 Common - hypothetical protein TTC0663 3 None None None 46199561 Common - probable hydrolase TTC1259 223 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 46198654 Nonpathogen - hypothetical protein TTC0346 1 None None None 46199256 Nonpathogen - hypothetical protein TTC0954 1 None None None 46199703 Common - high-affinity iron permease TTC1401 29 COG3258 COG3258, Cytochrome c Energy production and conversion 46200017 Common - thermostable carboxypeptidase 1 TTC1715 82 COG2317 COG2317, Zn-dependent carboxypeptidase Amino acid transport and metabolism 46199986 Common - hypothetical protein TTC1684 4 None None None 46199075 Common - subunit II of C(O/B)3-type cytochrome c oxidase TTC0769 87 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 46200266 Common rpmB 50S ribosomal protein L28 TTC1964 4 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 46198518 Common - uridine kinase TTC0210 103 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 46199974 Common - cytochrome c oxidase polypeptide II TTC1672 161 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 46199502 Common - stage II sporulation protein D TTC1200 48 COG2385 SpoIID, Sporulation protein and related proteins Cell division and chromosome partitioning 46199448 Common - hypothetical protein TTC1146 13 COG2353 COG2353, Uncharacterized conserved protein Function unknown 46199517 Common gntR putative transcriptional regulator, gntR family protein TTC1215 134 COG1802 GntR, Transcriptional regulators Transcription 46198914 Common paaC phenylacetic acid degradation protein paaC TTC0606 45 COG3396 COG3396, Uncharacterized conserved protein Function unknown 46199171 Common - 3-isopropylmalate dehydrogenase TTC0867 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 46198329 Nonpathogen - ferredoxin TTC0021 3 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 46199273 Common - dipeptide-binding protein TTC0971 214 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 46199654 Common curD putative heme peroxidase TTC1352 30 COG3253 COG3253, Uncharacterized conserved protein Function unknown 46199222 Common - protein kinase-like protein TTC0918 145 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 46199745 Common mgsA methylglyoxal synthase TTC1443 88 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 46198868 Common - phosphopantetheine adenylyltransferase TTC0560 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 46199512 Common - hypothetical protein TTC1210 71 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 46199792 Common - initial dioxygenase ferredoxin subunit TTC1490 89 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 46198526 Common livG branched-chain amino acid transport ATP-binding protein livG TTC0218 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 46198410 Common appF oligopeptide transport ATP-binding protein appF TTC0102 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 46199393 Common - putative membrane anchor of succinate dehydrogenase TTC1091 13 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 46199747 Common thiI thiamine biosynthesis protein thiI TTC1445 93 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 46199462 Common - serine hydroxymethyltransferase TTC1160 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 46199966 Common - hypothetical protein TTC1664 139 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 46199850 Nonpathogen - hypothetical protein TTC1548 1 COG1598 COG1598, Uncharacterized conserved protein Function unknown 46198808 Common - pyrroline-5-carboxylate reductase TTC0500 212 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 46199174 Common - putative dehydrogenase TTC0870 211 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 46198991 Common - hypothetical conserved metal-binding protein TTC0683 49 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 46198310 Common - dehydrogenase TTC0002 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 46199090 Common - uracil-DNA glycosylase TTC0784 116 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 46200113 Common - cold shock protein TTC1811 178 COG1278 CspC, Cold shock proteins Transcription 46199408 Common dnaB dnaB replication fork helicase TTC1106 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 46199003 Common mgtE Mg(2+) transporter mgtE TTC0695 201 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 46198718 Common - short chain dehydrogenase TTC0410 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 46198922 Common - hypothetical protein TTC0614 27 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 46198481 Common radA DNA repair protein RadA TTC0173 201 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 46199275 Common dppC dipeptide transport system permease protein dppC TTC0973 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 46199685 Nonpathogen - hypothetical protein/cluster function: phosphoribosylformylglycinamidine synthase TTC1383 44 COG1371 COG1371, Uncharacterized conserved protein Function unknown 46199097 Common merR transcriptional regulator, merR family TTC0791 134 COG0789 SoxR, Predicted transcriptional regulators Transcription 46198854 Common smpB SsrA-binding protein TTC0546 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 46198459 Common - glycine dehydrogenase subunit 2 TTC0151 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 46200134 Nonpathogen - hypothetical protein TTC1832 1 None None None 46199083 Common - two-component response regulator TTC0777 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 46198373 Nonpathogen - hypothetical protein TTC0065 1 None None None 46198727 Common - ABC transporter permease protein TTC0419 82 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 46198837 Common - UDP-galactopyranose mutase TTC0529 54 COG0562 Glf, UDP-galactopyranose mutase Cell envelope biogenesis, outer membrane 46198825 Common - probable chlorohydrolase TTC0517 156 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 46200145 Nonpathogen - hypothetical protein TTC1843 1 None None None 46199446 Common - 4-carboxymuconolactone decarboxylase TTC1144 84 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 46199716 Common - fructose-bisphosphate aldolase TTC1414 179 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 46200286 Nonpathogen - hypothetical protein TTC1984 1 None None None 46199782 Common - alanyl-tRNA synthetase TTC1480 248 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 46199327 Common engA GTP-binding protein EngA TTC1025 239 COG1160 COG1160, Predicted GTPases General function prediction only 46198488 Nonpathogen - hypothetical protein TTC0180 1 None None None 46199622 Nonpathogen - 50S ribosomal protein L29 TTC1320 1 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 46200259 Common bmrU protein bmrU TTC1957 98 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 46200124 Common - thio-disulfide isomerase/thioredoxin TTC1822 77 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 46199313 Nonpathogen - hypothetical protein TTC1011 3 None None None 46198736 Common pyrR pyrimidine regulatory protein PyrR TTC0428 111 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 46198417 Common - hypothetical protein TTC0109 63 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 46198400 Common - putative dihydropteridine reductase TTC0092 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 46198860 Common - esterase TTC0552 135 COG0824 FcbC, Predicted thioesterase General function prediction only 46199482 Common comA comA operon protein 2 TTC1180 100 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 46199467 Nonpathogen - hypothetical protein TTC1165 1 None None None 46199812 Common - serine/threonine protein phosphatase TTC1510 70 COG0622 COG0622, Predicted phosphoesterase General function prediction only 46198474 Common - aspartokinase TTC0166 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 46199660 Common pacS cation-transporting ATPase pacS TTC1358 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 46199771 Nonpathogen - aminomethyltransferase TTC1469 12 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 46198785 Common acuB acetoin utilization acuB protein TTC0477 200 COG0517 COG0517, FOG: CBS domain General function prediction only 46199801 Nonpathogen - hypothetical protein TTC1499 2 None None None 46198534 Common - galactokinase TTC0226 82 COG0153 GalK, Galactokinase Carbohydrate transport and metabolism 46198425 Common - threonine synthase TTC0117 134 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 46199984 Nonpathogen - hypothetical membrane spanning protein TTC1682 1 None None None 46199721 Common lytR membrane-bound protein lytR TTC1419 43 COG1316 LytR, Transcriptional regulator Transcription 46199417 Nonpathogen - hypothetical protein TTC1115 11 None None None 46199025 Common - UDP-N-acetylmuramoylalanine-D-glutamate ligase TTC0717 208 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 46198768 Common - phosphoribosylamine-glycine ligase TTC0460 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 46200164 Common - hypothetical protein TTC1862 112 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 46198847 Nonpathogen - hypothetical protein TTC0539 4 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 46199728 Common rtcB rtcB protein TTC1426 118 COG1690 RtcB, Uncharacterized conserved protein Function unknown 46200114 Common dnaJ chaperone protein dnaJ TTC1812 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 46200215 Common - NADH-quinone oxidoreductase chain H TTC1913 181 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 46199060 Common - hypothetical membrane spanning protein TTC0754 28 COG1963 COG1963, Uncharacterized protein conserved in bacteria Function unknown 46199645 Common - sugar fermentation stimulation protein TTC1343 45 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 46199349 Common - sulfide dehydrogenase (flavocytochrome C) TTC1047 57 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 46199910 Common dnaA chromosomal replication initiator protein dnaA TTC1608 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 46198436 Common glcE (S)-2-hydroxy-acid oxidase subunit glcE TTC0128 57 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 46199326 Common - putative acyltransferase TTC1024 56 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 46200002 Common - dihydrolipoamide dehydrogenase TTC1700 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 46200252 Common - ammonium transporter TTC1950 193 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 161611246 Common rpmI 50S ribosomal protein L35 TTC0184 98 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 46199757 Common - transporter TTC1455 40 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 46200228 Nonpathogen - hypothetical protein TTC1926 1 None None None 46198775 Common - sodium/proline symporter TTC0467 157 COG4147 DhlC, Predicted symporter General function prediction only 46199245 Common - hypothetical protein TTC0943 10 COG3369 COG3369, Uncharacterized conserved protein Function unknown 46199224 Common - hypothetical membrane spanning protein TTC0920 168 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 46199824 Nonpathogen - hypothetical protein TTC1522 1 None None None 46198580 Nonpathogen - hypothetical protein TTC0272 1 None None None 46198829 Nonpathogen gatC aspartyl/glutamyl-tRNA amidotransferase subunit C TTC0521 9 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 46198530 Common - UDP-glucose 4-epimerase, putative TTC0222 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 46198354 Common - acyl carrier protein TTC0046 210 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 46198984 Common - methylmalonyl-CoA mutase small subunit TTC0676 114 COG2185 Sbm, Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding) Lipid metabolism 46198496 Nonpathogen - hypothetical protein TTC0188 5 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 46199549 Common - hypothetical protein TTC1247 44 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 46198933 Common - multidrug resistance protein B TTC0625 177 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 46198820 Common - hypothetical protein TTC0512 14 COG1610 COG1610, Uncharacterized conserved protein Function unknown 46199372 Common - purine nucleoside phosphorylase TTC1070 89 COG0813 DeoD, Purine-nucleoside phosphorylase Nucleotide transport and metabolism 46198350 Nonpathogen - hypothetical protein TTC0042 1 None None None 46199942 Common - folylpolyglutamate synthase TTC1640 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 46199676 Common scU IscU protein TTC1374 182 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 46198576 Common chlI magnesium-chelatase subunit chlI TTC0268 39 COG1239 ChlI, Mg-chelatase subunit ChlI Coenzyme metabolism 46199278 Common - multidrug resistance ABC transporter ATP-binding and permease protein TTC0976 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 46198491 Common infC translation initiation factor IF-3 TTC0183 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 46200029 Common - tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase TTC1727 214 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 46198545 Common maoC dehydrogenase TTC0237 119 COG2030 MaoC, Acyl dehydratase Lipid metabolism 46200076 Nonpathogen - hypothetical protein TTC1774 8 COG3584 COG3584, Uncharacterized protein conserved in bacteria Function unknown 46198349 Common - methyltransferase TTC0041 133 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 46199940 Common - porphobilinogen deaminase TTC1638 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 46199695 Common - acetylornithine aminotransferase/N-acetyllysine aminotransferase TTC1393 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 46199398 Common - ABC transporter permease protein TTC1096 12 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 46199068 Nonpathogen - hypothetical protein TTC0762 1 None None None 46199435 Nonpathogen - hypothetical protein TTC1133 5 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 46198426 Nonpathogen - hypothetical protein TTC0118 1 None None None 46199524 Common - DNA gyrase subunit B TTC1222 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 46199928 Common - cold shock protein TTC1626 182 COG1278 CspC, Cold shock proteins Transcription 46199288 Common - putative peptidase TTC0986 15 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 46199239 Common - putative transport system permease ABC transporter protein TTC0935 71 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 46199461 Nonpathogen - hypothetical protein TTC1159 1 None None None 46199957 Common - putative isochorismatase TTC1655 163 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 46198717 Common sufE sufE protein TTC0409 20 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 46198630 Nonpathogen - hypothetical protein TTC0322 2 None None None 46199187 Nonpathogen - protein kinase-like protein TTC0883 1 None None None 46199684 Common - hypothetical cytosolic protein TTC1382 9 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 46199115 Common trkG trk system potassium uptake protein trkG TTC0809 119 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 46199436 Common - elongation factor G TTC1134 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 46198511 Common - probable small heat shock protein TTC0203 91 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 46199088 Nonpathogen - hypothetical protein TTC0782 1 COG4509 COG4509, Uncharacterized protein conserved in bacteria Function unknown 46199167 Nonpathogen - hypothetical protein TTC0863 1 COG1354 COG1354, Uncharacterized conserved protein Function unknown 46198365 Common - NADH dehydrogenase TTC0057 81 COG0778 NfnB, Nitroreductase Energy production and conversion 46199422 Common - small heat shock protein TTC1120 93 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 46199337 Common - hypothetical membrane spanning protein TTC1035 17 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 46199491 Common - hypothetical protein TTC1189 13 COG4274 COG4274, Uncharacterized conserved protein Function unknown 46199101 Common - amino acid ABC transporter, ATP-binding protein TTC0795 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 46198693 Common - dihydrodipicolinate synthase TTC0385 212 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 46199330 Common - homoserine kinase TTC1028 83 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 46199602 Common - DNA-directed RNA polymerase subunit alpha TTC1300 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 46199454 Common - hypothetical cytosolic protein TTC1152 6 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 46198968 Nonpathogen - hypothetical protein TTC0660 1 None None None 46199736 Nonpathogen - hypothetical protein TTC1434 1 None None None 46200080 Common - NAD(P) transhydrogenase subunit beta TTC1778 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 46199840 Common - NH(3)-dependent NAD(+) synthetase TTC1538 233 COG0171 NadE, NAD synthase Coenzyme metabolism 46198882 Nonpathogen - hypothetical protein TTC0574 1 None None None 46199262 Common mutS DNA mismatch repair protein TTC0960 205 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 46199651 Common - hypothetical protein TTC1349 15 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 46199996 Nonpathogen - hypothetical protein TTC1694 1 None None None 46200290 Common - molybdenum cofactor biosynthesis protein A TTC1988 207 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 46199847 Nonpathogen - hypothetical protein TTC1545 1 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 46199559 Common - small heat shock protein TTC1257 172 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 46199644 Common - putative divalent heavy-metal cations transporter TTC1342 11 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 46199874 Common - alcohol dehydrogenase TTC1572 162 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 46200066 Common - adenylosuccinate synthetase TTC1764 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 46198614 Common - putative oxidoreductase TTC0306 59 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 46198763 Common - transcriptional repressor TTC0455 128 COG1609 PurR, Transcriptional regulators Transcription 46198556 Nonpathogen - hypothetical protein TTC0248 1 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 46199450 Common - putative nucleotidyltransferase TTC1148 40 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 46198568 Common - phosphoenolpyruvate carboxylase TTC0260 117 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 46198468 Common - ADP-ribose pyrophosphatase TTC0160 107 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 46200180 Nonpathogen - hypothetical protein TTC1878 2 None None None 46198437 Common - (S)-2-hydroxy-acid oxidase chain D TTC0129 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 46199229 Common - ferric uptake regulation protein TTC0925 141 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 46199762 Common - DNA-directed RNA polymerase beta' chain TTC1460 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 46198884 Nonpathogen - hypothetical protein TTC0576 1 None None None 46198660 Common - pyridoxine biosynthesis protein TTC0352 87 COG0214 SNZ1, Pyridoxine biosynthesis enzyme Coenzyme metabolism 46199891 Common - hypothetical cytosolic protein TTC1589 18 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 46200038 Nonpathogen secE preprotein translocase subunit SecE TTC1736 7 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 46199289 Common - transcriptional regulatory protein TTC0987 218 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 46199596 Nonpathogen - hypothetical protein TTC1294 1 COG3147 DedD, Uncharacterized protein conserved in bacteria Function unknown 46199790 Common - ABC transporter ATP-binding protein TTC1488 187 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 46199027 Common - UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase TTC0719 121 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 46199610 Common secY preprotein translocase subunit SecY TTC1308 243 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 46198394 Common - rrf2 family protein TTC0086 180 COG1959 COG1959, Predicted transcriptional regulator Transcription 46199401 Common - long-chain-fatty-acid-CoA ligase TTC1099 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 46198430 Nonpathogen - hypothetical cytosolic protein TTC0122 2 None None None 46199017 Nonpathogen - hypothetical protein TTC0709 1 None None None 46200010 Common - threonine dehydratase TTC1708 195 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 46198441 Common - N-acyl-L-amino acid amidohydrolase TTC0133 188 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 46199335 Common - tyrosyl-tRNA synthetase TTC1033 244 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 46198678 Common - Histidinol dehydrogenase TTC0370 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 46200264 Common trkA trk system potassium uptake protein trkA TTC1962 43 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 46199705 Common - polysulfide reductase chain C TTC1403 39 COG5557 COG5557, Polysulphide reductase Energy production and conversion 46198872 Common - glutamate-1-semialdehyde 2,1-aminomutase TTC0564 236 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 46199395 Common - S-adenosylmethionine decarboxylase proenzyme TTC1093 62 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 46199498 Nonpathogen rpoZ RNA polymerase-associated protein rpoZ, omega subunit TTC1196 2 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 46199888 Common - acetylglutamate kinase TTC1586 172 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 46200072 Common - alanine dehydrogenase TTC1770 167 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 46199533 Common - protein phosphatase 2C TTC1231 115 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 46199915 Common - metal dependent hydrolase TTC1613 13 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 46199609 Common - adenylate kinase TTC1307 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 46199440 Common - two-component response regulator TTC1138 226 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 46200106 Common - hypothetical protein TTC1804 5 COG4113 COG4113, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 161611242 Common - S-adenosylmethionine synthetase TTC1279 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 46199050 Nonpathogen - hypothetical conserved membrane spanning protein TTC0744 3 COG0795 COG0795, Predicted permeases General function prediction only 46198502 Common - purine nucleoside phosphorylase TTC0194 88 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 46198795 Common - putative transferase/hydrolase TTC0487 173 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 46199836 Common - NAD(FAD)-utilizing enzyme TTC1534 105 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 46199804 Common - arsenate reductase TTC1502 130 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 46199871 Nonpathogen - putative cytochrome c TTC1569 2 None None None 46198743 Common - glutaryl-CoA dehydrogenase TTC0435 159 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 46199472 Nonpathogen - hypothetical protein TTC1170 3 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 46200060 Common - hypothetical protein TTC1758 123 COG1576 COG1576, Uncharacterized conserved protein Function unknown 46199835 Common - glucosamine-fructose-6-phosphate aminotransferase [isomerizing] TTC1533 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 46198558 Common - ATP-dependent clp protease proteolytic subunit TTC0250 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 46198571 Common - hypothetical protein TTC0263 119 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 46198924 Common - dihydroorotate dehydrogenase TTC0616 37 COG1980 COG1980, Archaeal fructose 1,6-bisphosphatase Carbohydrate transport and metabolism 46198803 Common - phosphohydrolase TTC0495 15 COG1768 COG1768, Predicted phosphohydrolase General function prediction only 46199816 Common - sugar-binding protein TTC1514 110 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 46200091 Nonpathogen - hypothetical protein TTC1789 2 None None None 46198823 Common lmbE lmbE-related protein TTC0515 30 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 46200054 Nonpathogen - hypothetical protein TTC1752 1 None None None 46199661 Nonpathogen - hypothetical protein TTC1359 4 COG3462 COG3462, Predicted membrane protein Function unknown 46200244 Common - primosomal protein N' TTC1942 196 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 46200219 Common - NADH-quinone oxidoreductase chain D TTC1917 192 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 46199231 Common - putative ribosomal associated protein TTC0927 170 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 46199363 Nonpathogen - hypothetical protein TTC1061 1 None None None 46199120 Nonpathogen - hypothetical protein TTC0814 1 None None None 46199445 Common hemD putative uroporphyrinogen-III synthase hemD TTC1143 12 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 46200057 Nonpathogen - hypothetical protein TTC1755 7 None None None 46200173 Common lysR transcriptional regulatory protein, lysR family (hydrogen peroxide-inducible genes activator) TTC1871 180 COG0583 LysR, Transcriptional regulator Transcription 46198667 Common aspS aspartyl-tRNA synthetase TTC0359 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 46199139 Nonpathogen - hypothetical protein TTC0833 2 None None None 46199976 Common - permease TTC1674 130 COG0628 PerM, Predicted permease General function prediction only 46200044 Common rpsR 30S ribosomal protein S18 TTC1742 212 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 46200069 Common - ribosomal large subunit pseudouridine synthase B TTC1767 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 46198705 Common - L-allo-threonine aldolase TTC0397 86 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 46200019 Common - hypothetical protein TTC1717 10 None None None 46199542 Common - hypothetical protein TTC1240 10 None None None 46198374 Nonpathogen - hypothetical protein TTC0066 1 None None None 46198628 Common - sugar transport protein TTC0320 66 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 46199212 Nonpathogen - V-type ATP synthase subunit F TTC0908 6 COG1436 NtpG, Archaeal/vacuolar-type H+-ATPase subunit F Energy production and conversion 46198649 Common - putative hydrolase TTC0341 77 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 46200128 Nonpathogen - hypothetical protein TTC1826 1 COG1341 COG1341, Predicted GTPase or GTP-binding protein General function prediction only 46199551 Common - adenine phosphoribosyltransferase TTC1249 7 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 46198608 Common - transporter TTC0300 63 COG0679 COG0679, Predicted permeases General function prediction only 46200226 Nonpathogen - hypothetical protein TTC1924 1 None None None 46199347 Common - cytochrome c TTC1045 33 COG3258 COG3258, Cytochrome c Energy production and conversion 46198549 Common - aspartate alpha-decarboxylase TTC0241 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 46198453 Nonpathogen - hypothetical protein TTC0145 1 COG2380 COG2380, Uncharacterized protein conserved in bacteria Function unknown 46199176 Nonpathogen - cytochrome c-552 precursor TTC0872 1 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 46199743 Common - transporter TTC1441 11 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 46199148 Common - ABC transporter permease protein TTC0842 22 COG3694 COG3694, ABC-type uncharacterized transport system, permease component General function prediction only 46199514 Common - glutamate dehydrogenase TTC1212 165 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 46200241 Nonpathogen - hypothetical protein TTC1939 1 None None None 46199631 Common rpsJ 30S ribosomal protein S10 TTC1329 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 46199173 Common - hypothetical protein TTC0869 21 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 46199821 Common - bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) TTC1519 72 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 46199508 Nonpathogen - hypothetical protein TTC1206 1 COG4723 COG4723, Phage-related protein, tail component Function unknown 46200121 Common - transcriptional regulator TTC1819 66 COG1309 AcrR, Transcriptional regulator Transcription 46198509 Common tdh L-threonine 3-dehydrogenase TTC0201 209 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 46198998 Common - DNA polymerase I TTC0690 221 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 46198485 Common - aspartate-semialdehyde dehydrogenase TTC0177 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 46199519 Common - hypothetical protein TTC1217 14 COG1462 CsgG, Uncharacterized protein involved in formation of curli polymers Cell envelope biogenesis, outer membrane 46199406 Common - glutamate synthase [NADPH] large chain TTC1104 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 46198916 Common paaA phenylacetic acid degradation protein paaA TTC0608 45 COG3396 COG3396, Uncharacterized conserved protein Function unknown 46199001 Common - S-adenosylmethionine:tRNA ribosyltransferase-isomerase TTC0693 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 46199196 Common - hypothetical protein TTC0892 61 COG0393 COG0393, Uncharacterized conserved protein Function unknown 46198412 Common - putative T-histone deacetylase TTC0104 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 46199427 Common dnaJ chaperone protein dnaJ TTC1125 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 46198312 Common - hypothetical protein TTC0004 38 COG2815 COG2815, Uncharacterized protein conserved in bacteria Function unknown 46199141 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein TTC0835 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 46199020 Nonpathogen - hypothetical protein TTC0712 1 None None None 46199264 Common - cytochrome c-552 precursor TTC0962 57 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 46200197 Common - heat resistant RNA dependent ATPase TTC1895 245 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 46199712 Common - hypothetical cytosolic protein TTC1410 60 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 46199799 Nonpathogen - hypothetical protein TTC1497 1 None None None 46199190 Common - acetyl-coenzyme A synthetase TTC0886 215 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 46198814 Common - ribosome recycling factor (rrf) TTC0506 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 46199250 Common - UDP-N-acetylglucosamine 2-epimerase TTC0948 150 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 46199388 Nonpathogen - hypothetical protein TTC1086 1 None None None 46200234 Nonpathogen - hypothetical protein TTC1932 1 None None None 46199828 Common - Predicted acyl-CoA transferase/carnitine dehydratase TTC1526 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 46199500 Common - putative pullulanase TTC1198 151 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 46199574 Common hesB hesB protein TTC1272 167 COG0316 IscA, Uncharacterized conserved protein Function unknown 46199477 Common - putative oxidoreductase-like protein TTC1175 36 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 46199582 Common - glutamate racemase TTC1280 191 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 46199151 Common - putative alpha-isopropylmalate/homocitrate synthase family transferase TTC0847 189 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 46199859 Nonpathogen - hypothetical protein TTC1557 2 None None None 46198594 Common - acetyltransferase TTC0286 198 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 46199105 Common - hypothetical protein TTC0799 33 None None None 46199617 Common rpsN 30S ribosomal protein S14 TTC1315 155 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 46199608 Common - methionine aminopeptidase TTC1306 249 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 46200268 Common - (S)-2-hydroxy-acid oxidase chain D TTC1966 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 46198961 Nonpathogen - hypothetical protein TTC0653 1 None None None 46198524 Common livM branched-chain amino acid transport system permease protein livM TTC0216 117 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 46199117 Common - Fe-S oxidoreductase TTC0811 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 46198337 Common - hypothetical membrane spanning protein TTC0029 25 COG0795 COG0795, Predicted permeases General function prediction only 46199286 Common - putative DNA binding protein TTC0984 212 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 46199127 Nonpathogen - hypothetical protein TTC0821 1 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 46200166 Common dcd deoxycytidine triphosphate deaminase TTC1864 153 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 46199377 Common - excinuclease ABC subunit A TTC1075 244 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 46198754 Common - putative response regulator TTC0446 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 46199647 Common - Integral membrane protein TTC1345 13 COG3274 COG3274, Uncharacterized protein conserved in bacteria Function unknown 46200000 Common kgd alpha-ketoglutarate decarboxylase TTC1698 147 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 46199324 Common - holo-[acyl-carrier protein] synthase TTC1022 89 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 46199968 Nonpathogen - hypothetical protein TTC1666 3 None None None 46199142 Common argC N-acetyl-gamma-glutamyl-phosphate reductase TTC0836 215 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 46199353 Common - hypothetical protein TTC1051 14 COG3474 COG3474, Cytochrome c2 Energy production and conversion 46200108 Common - DNA polymerase III alpha subunit TTC1806 222 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 46198940 Nonpathogen - hypothetical protein TTC0632 1 None None None 46198842 Common - enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase/3-hydroxyacyl-CoA dehydrogenase TTC0534 162 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 46198652 Nonpathogen - hypothetical protein TTC0344 5 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 46198539 Common hemH ferrochelatase TTC0231 170 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 46199066 Common - protein translation elongation factor P (EF-P) TTC0760 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 46199822 Common fimA major pilin protein fimA TTC1520 39 COG3342 COG3342, Uncharacterized conserved protein Function unknown 46199247 Nonpathogen - hypothetical protein TTC0945 2 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 46198407 Common appB oligopeptide transport system permease protein appB TTC0099 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 46200250 Common hrcA heat-inducible transcription repressor hrcA TTC1948 130 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 46198547 Common tetR transcriptional regulator, tetR family TTC0239 160 COG1309 AcrR, Transcriptional regulator Transcription 46199153 Common - 2-isopropylmalate synthase TTC0849 214 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 46199226 Common - hypothetical protein TTC0922 88 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 46198612 Common - pyruvate phosphate dikinase TTC0304 216 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 46199059 Nonpathogen - hypothetical protein TTC0753 1 None None None 46198532 Common - thiol-disulfide isomerase/thioredoxin TTC0224 66 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 46198911 Common - hypothetical protein TTC0603 16 COG5496 COG5496, Predicted thioesterase General function prediction only 46198646 Common - leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein TTC0338 144 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 46199535 Common - putative permease TTC1233 63 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 46199414 Nonpathogen - hypothetical protein TTC1112 1 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 46199971 Nonpathogen - hypothetical protein TTC1669 3 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 46198419 Common - probable serine/threonine protein phosphatase TTC0111 23 COG0622 COG0622, Predicted phosphoesterase General function prediction only 46199240 Common - probable ATP transporter, ATP-binding protein TTC0938 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 46199526 Common - peptidyl-tRNA hydrolase TTC1224 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 46198476 Common - malate dehydrogenase TTC0168 159 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 46199272 Common livF branched-chain amino acid transport ATP-binding protein livF TTC0970 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 46199982 Nonpathogen - hypothetical protein TTC1680 1 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 46199381 Common hisF hisF protein TTC1079 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 46198835 Common - glycosyltransferase TTC0527 167 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 46199156 Common - acetolactate synthase large subunit TTC0852 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 46199778 Common - transporter TTC1476 143 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 46200143 Nonpathogen - hypothetical protein TTC1841 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 46199624 Common rpsC 30S ribosomal protein S3 TTC1322 248 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 46199707 Nonpathogen - hypothetical protein TTC1405 7 None None None 46199370 Common - hypothetical protein TTC1068 17 COG3294 COG3294, Uncharacterized conserved protein Function unknown 46199863 Nonpathogen - hypothetical protein TTC1561 1 None None None 46199692 Common - putative mannosyltransferase TTC1390 16 None None None 46198974 Common - thiosulfate sulfurtransferase TTC0666 146 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 46198734 Common pyrC dihydroorotase TTC0426 212 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 46199714 Common - thymidine phosphorylase TTC1412 118 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 46199961 Common - phosphopentomutase TTC1659 70 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 46199073 Common - gliding motility protein TTC0767 22 COG2229 COG2229, Predicted GTPase General function prediction only 46198402 Nonpathogen - probable cysteinyl-tRNA synthetase TTC0094 3 COG3557 COG3557, Uncharacterized domain/protein associated with RNAses G and E Translation, ribosomal structure and biogenesis 46200199 Nonpathogen - hypothetical membrane spanning protein TTC1897 5 None None None 46198935 Common - hypothetical protein TTC0627 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 46198862 Common - exoribonuclease II TTC0554 192 COG0557 VacB, Exoribonuclease R Transcription 46198782 Common ftsK cell division protein ftsK TTC0474 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 46200189 Common - hypothetical protein TTC1887 17 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 46198789 Common - membrane metalloprotease TTC0481 75 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 46199470 Common - putative oligoendopeptidase F protein TTC1168 88 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 46198367 Nonpathogen - hypothetical protein TTC0059 1 None None None 46199682 Common pyrE orotate phosphoribosyltransferase TTC1380 138 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 46200161 Common - bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) TTC1859 29 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 46198715 Common - homoserine O-acetyltransferase TTC0407 143 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 46200100 Common - nucleoside diphosphate kinase TTC1798 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 46198382 Common - probable jag protein TTC0074 56 COG1847 Jag, Predicted RNA-binding protein General function prediction only 46199086 Common - electron transfer flavoprotein beta-subunit TTC0780 146 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 46199994 Common - universal stress protein family TTC1692 164 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 46199738 Common - molybdenum cofactor biosynthesis protein C TTC1436 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 46198801 Common asnC transcriptional regulatory protein, asnC family TTC0493 45 COG1522 Lrp, Transcriptional regulators Transcription 46199452 Common - hypothetical cytosolic protein TTC1150 12 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 46198478 Common - succinyl-CoA synthetase beta chain TTC0170 212 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 46198583 Common - undecaprenyl-phosphate galactosephosphotransferase TTC0275 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 46200082 Common - NAD/NADP transhydrogenase alpha subunit 1 TTC1780 165 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 46199786 Common - NADH oxidase TTC1484 245 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 46199106 Common - indole-3-glycerol phosphate synthase TTC0800 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 46199921 Common - phosphoribosylaminoimidazole synthetase TTC1619 232 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 46199634 Common - 30S ribosomal protein S7 TTC1332 248 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 46199881 Common - hypothetical protein TTC1579 101 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 46198637 Common - transcriptional repressor TTC0329 84 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 46199939 Common - peptidyl-prolyl cis-trans isomerase TTC1637 101 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 46200171 Nonpathogen - hypothetical protein TTC1869 1 None None None 46198839 Common - pyrrolidone-carboxylate peptidase TTC0531 55 COG2039 Pcp, Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) Posttranslational modification, protein turnover, chaperones 46199844 Common argC N-acetyl-gamma-glutamyl-phosphate reductase TTC1542 202 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 46198340 Common - dehydrogenase TTC0032 206 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 46199424 Nonpathogen - heat-stable protein TTC1122 1 None None None 46199568 Common sfuC iron(III)-transport ATP-binding protein sfuC TTC1266 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 46198356 Common - malonyl-CoA-[acyl-carrier-protein] transacylase TTC0048 208 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 46199674 Nonpathogen - hypothetical protein TTC1372 2 COG3462 COG3462, Predicted membrane protein Function unknown 46198352 Common - dNTP triphosphohydrolase TTC0044 160 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 46198982 Common - signal recognition particle protein ffh TTC0674 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 46198462 Common nrfC nrfC protein TTC0154 151 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 46198631 Nonpathogen - hypothetical protein TTC0323 1 COG3170 FimV, Tfp pilus assembly protein FimV Cell motility and secretion / Intracellular trafficking and secretion 46198563 Common - anthranilate synthase component II/para-aminobenzoate synthase glutamine amidotransferase component II TTC0255 225 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 46199208 Common - putative esterase TTC0904 14 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 46200257 Nonpathogen - acetyltransferase TTC1955 3 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 46199506 Nonpathogen - hypothetical protein TTC1204 1 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 46200276 Nonpathogen - hypothetical protein TTC1974 7 None None None 46199484 Common - excinuclease ABC subunit C TTC1182 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 46200078 Common rplL 50S ribosomal protein L7/L12 TTC1776 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 46199784 Nonpathogen - ABC transporter permease protein TTC1482 4 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 46199042 Common - sugar transport ATP-binding protein TTC0734 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 46198966 Nonpathogen - hypothetical protein TTC0658 1 None None None 46199693 Common - hypothetical protein TTC1391 44 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 46199019 Common mraW mraW protein TTC0711 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 46199944 Common - molybdopterin biosynthesis mog protein TTC1642 189 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 46198414 Common - veg136 protein TTC0106 147 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 46199433 Common - hypothetical membrane spanning protein TTC1131 31 COG1714 COG1714, Predicted membrane protein/domain Function unknown 46198494 Nonpathogen - hypothetical protein TTC0186 6 COG2426 COG2426, Predicted membrane protein Function unknown 46198830 Common - hypothetical membrane spanning protein TTC0522 35 COG1811 COG1811, Uncharacterized membrane protein, possible Na+ channel or pump General function prediction only 46198359 Nonpathogen - hypothetical protein TTC0051 10 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 46198986 Common czrB cadmium-zinc resistance protein czrB TTC0678 140 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 46198959 Nonpathogen - hypothetical protein TTC0651 1 None None None 46199035 Common - biotin synthase/thiamine biosynthesis enzyme TTC0727 84 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 46199132 Common mreC rod shape-determining protein mreC TTC0826 25 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 46198895 Common - hypothetical protein TTC0587 15 COG1510 COG1510, Predicted transcriptional regulators Transcription 46198428 Nonpathogen - hypothetical protein TTC0120 1 None None None 46198389 Common livM branched-chain amino acid transport system permease protein livM TTC0081 45 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 46199184 Common - hypothetical protein TTC0880 112 COG1733 COG1733, Predicted transcriptional regulators Transcription 46200190 Common - cofactor-independent phosphoglycerate mutase TTC1888 51 COG3635 COG3635, Predicted phosphoglycerate mutase, AP superfamily Carbohydrate transport and metabolism 46198471 Nonpathogen - hypothetical membrane spanning protein TTC0163 3 COG2510 COG2510, Predicted membrane protein Function unknown 46200193 Nonpathogen - hypothetical protein TTC1891 5 None None None 46198672 Common modB molybdenum transport system permease protein modB TTC0364 226 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 46198957 Common - ABC transporter permease protein TTC0649 168 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 46198401 Nonpathogen - probable transmembrane protein TTC0093 6 None None None 46198658 Common - hypothetical cytosolic protein TTC0350 111 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 46199199 Common - hypothetical protein TTC0895 41 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 46199098 Common - QAH/OAS sulfhydrylase TTC0792 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 46198416 Common - methyltransferase TTC0108 45 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 46199583 Common - hypothetical protein TTC1281 115 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 46200246 Common - alanine racemase TTC1944 199 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 46199130 Common - putative phosphoslipase TTC0824 92 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 46199192 Common - O-sialoglycoprotein endopeptidase TTC0888 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 46198669 Nonpathogen - hypothetical protein TTC0361 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 46199565 Common - hypothetical protein TTC1263 12 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 46200046 Common - lactate 2-monooxygenase TTC1744 109 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 46199271 Common livG branched-chain amino acid transport ATP-binding protein livG TTC0969 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 46198513 Common - glutamyl-tRNA(Gln) amidotransferase subunit A TTC0205 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 46198816 Common tsf elongation factor Ts TTC0508 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 46199385 Common - 4-hydroxybutyrate coenzyme A transferase TTC1083 101 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 46198939 Common attH attH protein TTC0631 47 COG5621 COG5621, Predicted secreted hydrolase General function prediction only 46198392 Common mntA manganese transport system ATP-binding protein mntA TTC0084 248 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 46200008 Common - carbamoyl phosphate synthase small subunit TTC1706 233 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 46198975 Common - L-serine dehydratase TTC0667 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 46198640 Common - bile acid-inducible operon protein F TTC0332 109 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 46199981 Nonpathogen - hypothetical protein TTC1679 3 None None None 46198950 Common - hypothetical protein TTC0642 47 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 46199033 Common ruvC crossover junction endodeoxyribonuclease ruvC TTC0725 197 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 46199978 Common - queuine tRNA-ribosyltransferase TTC1676 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 46198370 Common hisH imidazole glycerol phosphate synthase subunit HisH TTC0062 215 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 46200204 Nonpathogen - hypothetical protein TTC1902 1 None None None 46198681 Common - membrane-bound protein lytR TTC0373 63 COG1316 LytR, Transcriptional regulator Transcription 46199852 Common - 2-isopropylmalate synthase/Homocitrate synthase TTC1550 204 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 46198886 Nonpathogen - probable transposase TTC0578 7 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 46199225 Nonpathogen - hypothetical protein TTC0921 4 None None None 46200130 Common - amylopullulanase TTC1828 45 COG1449 COG1449, Alpha-amylase/alpha-mannosidase Carbohydrate transport and metabolism 46199614 Common rplR 50S ribosomal protein L18 TTC1312 215 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 46200254 Common - RNA methyltransferase, putative TTC1952 157 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 46199741 Common - hydrolase (HAD superfamily) TTC1439 31 COG2316 COG2316, Predicted hydrolase (HD superfamily) General function prediction only 46200198 Common - transketolase TTC1896 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 46199536 Common - delta-aminolevulinic acid dehydratase TTC1234 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 46198465 Common - probable two-component response regulator TTC0157 193 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 46199657 Common - guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase TTC1355 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 46199797 Nonpathogen - hypothetical protein TTC1495 1 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 46200051 Common - 3-hydroxyisobutyrate dehydrogenase TTC1749 162 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 46200288 Common - geranylgeranyl diphosphate synthetase TTC1986 226 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 46199878 Nonpathogen mutT mutator mutT protein (7,8-dihydro-8-oxoguanine-triphosphatase) TTC1576 3 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 46198857 Common - glyceraldehyde 3-phosphate dehydrogenase TTC0549 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 46200087 Common - Mg(2+) chelatase family protein TTC1785 189 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 46198343 Common ftsH cell division protein ftsH TTC0035 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 46198997 Common - hypothetical protein TTC0689 131 COG1739 COG1739, Uncharacterized conserved protein Function unknown 46199706 Common - anaerobic dimethyl sulfoxide reductase chain B TTC1404 138 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 46199218 Common - hypothetical protein TTC0914 122 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 46199513 Common - glutamate dehydrogenase TTC1211 180 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 46199404 Common - CTP synthetase TTC1102 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 46200137 Common - molybdopterin converting factor, small subunit TTC1835 43 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 46199095 Common - mercuric reductase TTC0789 241 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 46200062 Nonpathogen - hypothetical protein TTC1760 13 COG4911 COG4911, Uncharacterized conserved protein Function unknown 46199022 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-L-ornithine-D-alanyl-D-alanine ligase TTC0714 200 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 46199397 Common - ABC transporter ATP-binding protein TTC1095 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 46198506 Common hflX GTP-binding protein hflX TTC0198 210 COG2262 HflX, GTPases General function prediction only 46198833 Nonpathogen - hypothetical protein TTC0525 2 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 46198314 Common vdcC vdcC protein TTC0006 153 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 46198325 Common - UDP-N-acetylglucosamine pyrophosphorylase TTC0017 232 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 46200116 Common - bacitracin resistance protein (putative undecaprenol kinase) TTC1814 163 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 46199113 Common - amino acid ABC transporter, binding protein TTC0807 177 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 46199806 Common - transporter TTC1504 98 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 46198741 Common tldD tldD protein TTC0433 169 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 46199107 Common - phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase TTC0801 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 46199341 Common ccmE cytochrome c-type biogenesis protein CcmE TTC1039 94 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 46200056 Common - branched-chain alpha-keto acid dehydrogenase subunit E2 TTC1754 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 46199665 Common - S-layer repressor TTC1363 9 COG4447 COG4447, Uncharacterized protein related to plant photosystem II stability/assembly factor General function prediction only 46199690 Common - mannose-6-phosphate isomerase/mannose-1-phosphate guanylyl transferase (GDP) TTC1388 162 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 46199907 Common - putative partitioning protein TTC1605 226 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 46199233 Common - tail-specific protease TTC0929 187 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 46200232 Common - ribonucleoside-diphosphate reductase alpha chain TTC1930 182 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 46199892 Nonpathogen - hypothetical protein TTC1590 2 None None None 46199161 Nonpathogen comZ comZ TTC0857 1 COG4726 PilX, Tfp pilus assembly protein PilX Cell motility and secretion / Intracellular trafficking and secretion 46199265 Common - hypothetical protein TTC0963 30 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 46198440 Common merR probable transcriptional regulator, merR family TTC0132 82 COG0789 SoxR, Predicted transcriptional regulators Transcription 46200239 Nonpathogen - hypothetical protein TTC1937 3 None None None 46199294 Nonpathogen - hypothetical protein TTC0992 4 None None None 46200221 Common - NADH-quinone oxidoreductase chain B TTC1919 191 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 46199678 Common - 3-oxoadipate enol-lactonase TTC1376 117 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 46198376 Common tsY signal recognition particle receptor FtsY TTC0068 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 46198822 Common - chorismate mutase TTC0514 39 COG4401 AroH, Chorismate mutase Amino acid transport and metabolism 46199834 Common - S-layer protein TTC1532 21 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 46199295 Nonpathogen - hypothetical protein TTC0993 1 None None None 46198592 Common - pleiotropic regulatory protein TTC0284 196 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 46200262 Common - aspartate aminotransferase TTC1960 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 46199443 Nonpathogen - hypothetical protein TTC1141 1 None None None 46198647 Common maoC (R)-specific enoyl-CoA hydratase/maoC family protein TTC0339 92 COG2030 MaoC, Acyl dehydratase Lipid metabolism 46199220 Nonpathogen - hypothetical protein TTC0916 1 None None None 46200284 Common nifR tRNA-dihydrouridine synthase A TTC1982 211 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 46199214 Nonpathogen - V-type ATP synthase subunit E TTC0910 1 COG1390 NtpE, Archaeal/vacuolar-type H+-ATPase subunit E Energy production and conversion 46200065 Common - methyltransferase TTC1763 128 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 46200126 Common rpsA 30S ribosomal protein S1 TTC1824 216 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 46200033 Nonpathogen - hypothetical protein TTC1731 1 None None None 46198662 Common - cation-transporting ATPase TTC0354 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 46199764 Common - RNA-binding protein TTC1462 12 COG2302 COG2302, Uncharacterized conserved protein, contains S4-like domain Function unknown 46199766 Common mreB rod shape-determining protein mreB TTC1464 226 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 46199900 Common - corrin/porphyrin methyltransferase TTC1598 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 46198748 Common pilC pili assembly protein pilC TTC0440 151 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 46198611 Common - hypothetical protein TTC0303 7 None None None 46199029 Common - UDP-N-acetylenolpyruvoylglucosamine reductase TTC0721 193 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 46199364 Common uvrD DNA helicase uvrD TTC1062 230 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 46198878 Common - hypothetical protein TTC0570 205 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 46200101 Common - protein phosphatase 2C TTC1799 139 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 46198708 Nonpathogen - hypothetical protein TTC0400 1 None None None 46200020 Common - oxygen-insesitive NAD(P)H nitroreductase/dihydropteridine reductase TTC1718 84 COG0778 NfnB, Nitroreductase Energy production and conversion 46199008 Common rho transcription termination factor Rho TTC0700 203 COG1158 Rho, Transcription termination factor Transcription 46199128 Common - translation-associated GTPase TTC0822 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 46198941 Common - two-component response regulator TTC0633 217 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 46199726 Common rplU 50S ribosomal protein L21 TTC1424 215 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 46198908 Common livF branched-chain amino acid transport ATP-binding protein livF TTC0600 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 46198447 Common - sodium bicarbonate cotransporter TTC0139 31 COG3329 COG3329, Predicted permease General function prediction only 46199154 Common - ketol-acid reductoisomerase TTC0850 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 46198946 Common - probable ATP-dependent DNA helicase TTC0638 221 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 46199412 Common - hypothetical membrane spanning protein TTC1110 72 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 46199492 Common - hypothetical protein TTC1190 25 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 46199575 Common - Xaa-Pro aminopeptidase TTC1273 179 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 46199260 Common - ribonuclease activity regulator protein RraA TTC0958 80 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 46198804 Nonpathogen recX recombination regulator RecX TTC0496 1 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 46198699 Common fecD iron(III) dicitrate transport system permease protein fecD TTC0391 165 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 46199044 Nonpathogen - hypothetical protein TTC0736 2 None None None 46199528 Nonpathogen - hypothetical protein TTC1226 1 None None None 46198515 Nonpathogen - hypothetical protein TTC0207 2 None None None 46199866 Common - gamma-glutamyl phosphate reductase (GPR) TTC1564 187 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 46198824 Nonpathogen - hypothetical membrane spanning protein TTC0516 1 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 46198633 Common tolQ tolQ protein TTC0325 96 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 46199209 Common - V-type sodium ATP synthase subunit D TTC0905 43 COG1394 NtpD, Archaeal/vacuolar-type H+-ATPase subunit D Energy production and conversion 46199680 Common - glycerol-3-phosphate dehydrogenase [NAD(P)+] TTC1378 211 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 46199946 Nonpathogen - hypothetical protein TTC1644 1 COG3071 HemY, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 46199699 Common - putative response regulator protein TTC1397 177 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 46199071 Common - hypothetical protein TTC0765 166 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 46199232 Common ftsE cell division ATP-binding protein ftsE TTC0928 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 46198572 Common hslU ATP-dependent protease ATP-binding subunit TTC0264 212 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 46200207 Common - probable serine protease TTC1905 220 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 46199366 Common - metal dependent hydrolase TTC1064 112 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 46198898 Common - hypothetical protein TTC0590 13 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 46199923 Common pilT pili retraction protein pilT TTC1621 183 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 46199431 Common - methyltransferase TTC1129 109 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 46198473 Common - ribosomal RNA small subunit methyltransferase C TTC0165 66 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 46198627 Common thiC thiamine biosynthesis protein ThiC TTC0319 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 46199555 Common - histidine nucleotide-binding protein TTC1253 235 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 46198925 Common - hypothetical cytosolic protein TTC0617 148 COG1733 COG1733, Predicted transcriptional regulators Transcription 46200018 Common pilD type 4 prepilin peptidase pilD TTC1716 122 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 46199322 Common - 3-dehydroquinate synthase TTC1020 204 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 46199118 Nonpathogen - hypothetical protein TTC0812 2 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 46200149 Common - ribosomal small subunit pseudouridine synthase A TTC1847 203 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 46199012 Common ftsX cell division protein ftsX TTC0704 28 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 46198703 Nonpathogen - hypothetical protein TTC0395 1 None None None 46199426 Nonpathogen dnaJ dnaJ/dnaK assembly factor dafA TTC1124 1 None None None 46199375 Nonpathogen - hypothetical protein TTC1073 18 COG2045 COG2045, Phosphosulfolactate phosphohydrolase and related enzymes Coenzyme metabolism / General function prediction only 46198322 Nonpathogen - hypothetical protein TTC0014 2 COG2839 COG2839, Uncharacterized protein conserved in bacteria Function unknown 46198455 Common - hypothetical protein TTC0147 16 COG0433 COG0433, Predicted ATPase General function prediction only 46199953 Nonpathogen - hypothetical protein TTC1651 1 None None None 46198565 Common greA transcription elongation factor greA TTC0257 204 COG0782 GreA, Transcription elongation factor Transcription 46198360 Common - probable nitrilotriacetate monooxygenase component B TTC0052 51 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 46198335 Nonpathogen - hypothetical membrane spanning protein TTC0027 1 None None None 46200271 Common - oxidoreductase TTC1969 200 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 46199140 Nonpathogen - hypothetical protein TTC0834 2 None None None 46198891 Common - D-tyrosyl-tRNA deacylase TTC0583 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 46198980 Common - RNA-binding protein TTC0672 60 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 46199297 Common - transporter TTC0995 62 COG2928 COG2928, Uncharacterized conserved protein Function unknown 46199625 Common rplV 50S ribosomal protein L22 TTC1323 221 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 46198799 Common prkA prkA protein TTC0491 71 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 46199111 Common valS valyl-tRNA synthetase TTC0805 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 46198552 Common - tRNA (adenine-N(1)-)-methyltransferase TTC0244 61 COG2519 GCD14, tRNA(1-methyladenosine) methyltransferase and related methyltransferases Translation, ribosomal structure and biogenesis 46200073 Common - hypothetical protein TTC1771 27 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 46199656 Nonpathogen - hypothetical cytosolic protein TTC1354 2 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 46199570 Common - transporter TTC1268 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 46200093 Common - tripartite transporter, large subunit TTC1791 135 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 46198369 Common - imidazoleglycerol-phosphate dehydratase TTC0061 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 46199671 Common - hypothetical protein TTC1369 42 COG3439 COG3439, Uncharacterized conserved protein Function unknown 46199843 Common - acetylglutamate kinase TTC1541 209 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 46198386 Common livG branched-chain amino acid transport ATP-binding protein livG TTC0078 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 46198918 Common - DNA integration/recombination/invertion protein TTC0610 218 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 46199164 Common - hypothetical protein TTC0860 28 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 46199731 Common - hypothetical protein TTC1429 6 None None None 46199147 Common - hypothetical membrane spanning protein TTC0841 170 COG0344 COG0344, Predicted membrane protein Function unknown 46199459 Common - putative methyltransferase TTC1157 28 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 46199992 Common - deacetylase TTC1690 195 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 46198889 Common - triosephosphate isomerase TTC0581 216 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 46200278 Common - glucose-1-phosphate adenylyltransferase TTC1976 186 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 46199080 Common - polynucleotide phosphorylase/polyadenylase TTC0774 239 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 46198610 Nonpathogen - hypothetical protein TTC0302 2 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 46199751 Common - putative aminopeptidase TTC1449 6 COG2234 Iap, Predicted aminopeptidases General function prediction only 46200230 Common - myo-inositol-1(or 4)-monophosphatase TTC1928 200 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 46198541 Common - probable peptidyl-prolyl cis-trans isomerase TTC0233 119 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 46200163 Common - 3-oxoacyl-[acyl-carrier protein] reductase TTC1861 193 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 46199057 Common - methyltransferase TTC0751 14 None None None 46200157 Nonpathogen - hypothetical protein TTC1855 2 None None None 46200256 Common - deacetylase TTC1954 151 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 46198712 Common - putative beta-lactamase TTC0404 8 COG2367 PenP, Beta-lactamase class A Defense mechanisms 46198780 Common - spermine synthase TTC0472 128 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 46199544 Common - hypothetical protein TTC1242 109 COG0327 COG0327, Uncharacterized conserved protein Function unknown 46199421 Nonpathogen - heat-stable protein TTC1119 3 COG2129 COG2129, Predicted phosphoesterases, related to the Icc protein General function prediction only 46198902 Common - 4-hydroxyphenylacetate 3-monooxygenase TTC0594 50 COG2368 COG2368, Aromatic ring hydroxylase Secondary metabolites biosynthesis, transport, and catabolism 46198698 Common - iron(III) dicitrate-binding protein TTC0390 181 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 46199241 Common - molybdopterin-guanine dinucleotide biosynthesis protein A TTC0939 107 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 46199182 Common - cell division factor-like protein TTC0878 32 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 46199473 Common - putative ribonuclease TTC1171 189 COG0557 VacB, Exoribonuclease R Transcription 46198722 Common - mannitol-binding protein TTC0414 113 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 46198537 Nonpathogen - hypothetical membrane spanning protein TTC0229 2 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 46198797 Common - stage V sporulation protein R TTC0489 71 COG2719 SpoVR, Uncharacterized conserved protein Function unknown 46198937 Common - HD-hydrolase domain TTC0629 145 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 46199306 Common - serine protease TTC1004 148 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 46200150 Common - alanyl-tRNA synthetase related protein TTC1848 196 COG2872 COG2872, Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain General function prediction only 46198332 Common coA probable methylmalonyl-coA epimerase TTC0024 71 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 46198403 Nonpathogen - hypothetical protein TTC0095 1 None None None 46199865 Common - gamma-glutamyl kinase TTC1563 189 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 46199664 Common - hypothetical protein TTC1362 8 None None None 46199180 Common potA spermidine/putrescine transport ATP-binding protein potA TTC0876 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 46198773 Common - cyclic nucleotide binding protein/2 cbs domains TTC0465 136 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 46199829 Common - transporter TTC1527 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 46198758 Common yceI protein yceI TTC0450 115 COG2353 COG2353, Uncharacterized conserved protein Function unknown 46199310 Common - pantothenate kinase TTC1008 126 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 46200120 Common - transcriptional regulator TTC1818 76 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 46200182 Common - hypothetical protein TTC1880 30 None None None 46199701 Common - sulfide dehydrogenase (flavocytochrome C) TTC1399 126 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 46199311 Nonpathogen - hypothetical protein TTC1009 1 None None None 46199930 Common malF maltose transport system permease protein malF TTC1628 176 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 46200110 Nonpathogen - hypothetical protein TTC1808 1 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 46198864 Common - poly(A) polymerase/tRNA nucleotidyl transferase TTC0556 62 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 46199708 Common htpG chaperone protein htpG TTC1406 26 None None None 46198606 Common - hypothetical protein TTC0298 183 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 46199777 Nonpathogen - hypothetical protein TTC1475 1 None None None 46198432 Common - glycerate dehydrogenase/hydroxypyruvate reductase TTC0124 86 COG2379 GckA, Putative glycerate kinase Carbohydrate transport and metabolism 46200168 Common - ATP phosphoribosyltransferase TTC1866 210 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 46199150 Nonpathogen - integral membrane protein TTC0844 15 COG4587 COG4587, ABC-type uncharacterized transport system, permease component General function prediction only 46200142 Nonpathogen - hypothetical protein TTC1840 1 None None None 46198589 Nonpathogen - hypothetical protein TTC0281 1 None None None 46198439 Common clR transcriptional regulator, IclR family TTC0131 124 COG1414 IclR, Transcriptional regulator Transcription 46199355 Common - hypothetical protein TTC1053 12 None None None 46199038 Common - tryptophan synthase subunit beta TTC0730 227 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 46198747 Common - sua5 protein TTC0439 241 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 46198380 Nonpathogen - hypothetical protein TTC0072 2 COG4372 COG4372, Uncharacterized protein conserved in bacteria with the myosin-like domain Function unknown 46198943 Common - hypothetical protein TTC0635 29 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 46199724 Common obgE GTPase ObgE TTC1422 249 COG0536 Obg, Predicted GTPase General function prediction only 46199713 Common - cell wall endopeptidase, family M23/M37 TTC1411 193 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 46200274 Common - penicillin acylase TTC1972 76 COG2366 COG2366, Protein related to penicillin acylase General function prediction only 46199065 Common - biotin carboxyl carrier protein of acetyl-CoA carboxylase TTC0759 204 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 46200006 Common - hypothetical protein TTC1704 8 COG1598 COG1598, Uncharacterized conserved protein Function unknown 46198859 Nonpathogen - hypothetical protein TTC0551 1 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 46198641 Common - D-beta-hydroxybutyrate dehydrogenase TTC0333 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 46199649 Common - pyruvate formate-lyase activating enzyme TTC1347 99 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 46198765 Common - fumarylacetoacetate hydrolase family protein TTC0457 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 46200177 Common - galactoside O-acetyltransferase TTC1875 206 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 46198844 Common - acyl-CoA dehydrogenase TTC0536 164 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 46199202 Common - 3-hydroxybutyryl-CoA dehydrogenase TTC0898 161 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 46199611 Common rplO 50S ribosomal protein L15 TTC1309 217 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 46198973 Common - transposase TTC0665 91 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 46198756 Common - 3-deoxy-7-phosphoheptulonate synthase TTC0448 186 COG2876 AroA, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 46199227 Common sbcD putative exonuclease sbcD TTC0923 123 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 46199650 Common - hypothetical protein TTC1348 68 COG1355 COG1355, Predicted dioxygenase General function prediction only 46198327 Common tatC Sec-independent protein translocase protein tatC TTC0019 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 46199055 Common - ferric enterobactin esterase-related protein TTC0749 24 COG2382 Fes, Enterochelin esterase and related enzymes Inorganic ion transport and metabolism 46199616 Common rpsH 30S ribosomal protein S8 TTC1314 244 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 46198544 Common - medium-chain-fatty-acid-CoA ligase TTC0236 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 46198738 Common - putative permease TTC0430 10 COG0730 COG0730, Predicted permeases General function prediction only 46199795 Common - anthranilate synthase component I TTC1493 223 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 46198344 Nonpathogen - hypothetical protein TTC0036 2 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 46200251 Common - nitrogen regulatory protein p-II TTC1949 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 46198855 Common - hypothetical protein TTC0547 47 COG0388 COG0388, Predicted amidohydrolase General function prediction only 46199659 Common - hypothetical cytosolic protein TTC1357 75 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 46199402 Common rpsI 30S ribosomal protein S9 TTC1100 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 46200247 Nonpathogen - hypothetical protein TTC1945 2 None None None 46198316 Nonpathogen - O-sialoglycoprotein endopeptidase TTC0008 1 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 46198850 Common - hypothetical cytosolic protein TTC0542 11 COG1694 MazG, Predicted pyrophosphatase General function prediction only 46199078 Common - putative Permease TTC0772 86 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 46198489 Common - glutaminyl-tRNA synthetase TTC0181 237 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 46198995 Common - putative protease/transporter TTC0687 67 COG1030 NfeD, Membrane-bound serine protease (ClpP class) Posttranslational modification, protein turnover, chaperones 46199465 Common - putative odidoreductase TTC1163 186 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 46198806 Common - stage V sporulation protein S TTC0498 24 COG2359 SpoVS, Uncharacterized protein conserved in bacteria Function unknown 46199642 Nonpathogen - hypothetical protein TTC1340 1 None None None 46199024 Common - phospho-N-acetylmuramoyl-pentapeptide-transferase TTC0716 210 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 46199515 Common - 1-pyrroline-5-carboxylate dehydrogenase TTC1213 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 46199748 Common - amidase/amidotransferase TTC1446 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 46199854 Common - acyl-CoA dehydrogenase TTC1552 163 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 46199510 Nonpathogen - hypothetical protein TTC1208 1 None None None 46198818 Common - 4-aminobutyrate aminotransferase TTC0510 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 46200206 Common - UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase TTC1904 209 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 46199586 Common - nucleotidyltransferase TTC1284 51 COG2361 COG2361, Uncharacterized conserved protein Function unknown 46199950 Common - integral membrane protein TTC1648 143 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 46198932 Common - urea carboxylase/allophanate hydrolase TTC0624 115 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 46199927 Common surE survival protein surE TTC1625 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 46199895 Nonpathogen - hypothetical protein TTC1593 3 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 46198656 Common - hypothetical protein TTC0348 30 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 46199109 Common ecJ single-stranded DNA specific exonuclease RecJ TTC0803 198 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 46199046 Common murM murM TTC0738 23 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 46199383 Common glpX fructose 1,6-bisphosphatase II TTC1081 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 46198372 Common - inosine-5'-monophosphate dehydrogenase TTC0064 242 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 46199390 Common - protease I TTC1088 141 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 46199206 Common recG DNA helicase recG TTC0902 214 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 46198390 Common - leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein TTC0082 68 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 46199237 Common - bacterioferritin comigratory protein TTC0933 231 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 46198881 Common - ABC transporter ATP-binding protein TTC0573 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 46199636 Common - carboxypeptidase G2 precursor TTC1334 90 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 46199504 Common - transcriptional regulatory protein TTC1202 57 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 46198683 Common - hypothetical protein TTC0375 8 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 46199538 Common recR recombination protein recR TTC1236 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 46198597 Common - transposase TTC0289 43 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 46200035 Common - cleavage and polyadenylation specificity factor, 100 kDa subunit TTC1733 143 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 46198750 Nonpathogen - hypothetical protein TTC0442 1 None None None 46200089 Common - carboxylesterase TTC1787 60 COG2272 PnbA, Carboxylesterase type B Lipid metabolism 46199875 Common - glycerol-3-phosphate-binding protein TTC1573 107 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 46198433 Common - hypothetical protein TTC0125 17 COG3742 COG3742, Uncharacterized protein conserved in bacteria Function unknown 46199768 Common recA recombinase A TTC1466 214 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 46198666 Common phzF phenazine biosynthesis protein phzF TTC0358 105 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 46199114 Common - glycogen phosphorylase TTC0808 146 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 46199880 Common gufA zinc uptake transporter/gufA protein TTC1578 64 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 46198978 Common - tRNA (Guanine-N1)-methyltransferase TTC0670 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 46199913 Common - pyruvate kinase TTC1611 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 46200022 Nonpathogen - hypothetical protein TTC1720 2 None None None 46198964 Common - hypothetical protein TTC0656 13 None None None 46199006 Common - riboflavin synthase subunit alpha TTC0698 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 46198445 Common - phosphoribosylaminoimidazole carboxylase ATPase subunit TTC0137 193 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 46198876 Common - pyruvate dehydrogenase E1 component beta subunit TTC0568 167 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 46199136 Nonpathogen - hypothetical protein TTC0830 1 None None None 46198906 Common livH branched-chain amino acid transport system permease protein livH TTC0598 99 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 46199530 Common - two-component system histidine kinase TTC1228 19 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 46200218 Common - NADH-quinone oxidoreductase chain E TTC1916 157 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 46198993 Nonpathogen - hypothetical protein TTC0685 1 None None None 46198623 Common - thiamin-phosphate pyrophosphorylase TTC0315 204 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 46198948 Common - hypothetical protein TTC0640 7 COG3295 COG3295, Uncharacterized protein conserved in bacteria Function unknown 46199486 Common - ribose-phosphate pyrophosphokinase TTC1184 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 46199494 Common - propionyl-CoA carboxylase beta chain TTC1192 143 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 46199577 Common - hypothetical protein TTC1275 6 COG0400 COG0400, Predicted esterase General function prediction only 46200260 Common - probable nucleotidyltransferase TTC1958 35 None None None 46198901 Common - 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase TTC0593 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 46198617 Nonpathogen - hypothetical membrane spanning protein TTC0309 1 COG0730 COG0730, Predicted permeases General function prediction only 46198920 Common malG maltose transport system permease protein malG TTC0612 150 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 46199122 Common - protein-tyrosine phosphatase TTC0816 141 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 46198399 Common - hypothetical protein TTC0091 5 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 46199343 Common - heme exporter protein C TTC1041 162 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 46198929 Common - nicotinate-nucleotide pyrophosphorylase [carboxylating] TTC0621 203 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 46199144 Common - ornithine carbamoyltransferase TTC0838 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 46199831 Common - aminopeptidase TTC1529 64 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 46200179 Common - hypothetical protein TTC1877 30 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 46199418 Common - small heat shock protein TTC1116 85 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 46199593 Common - octaprenyl-diphosphate synthase TTC1291 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 46200058 Common - 2-oxoisovalerate dehydrogenase beta subunit TTC1756 190 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 46198664 Common asnC asparaginyl-tRNA synthetase TTC0356 249 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 46200211 Common - NADH-quinone oxidoreductase chain L TTC1909 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 46199884 Nonpathogen - hypothetical protein TTC1582 1 None None None 46199988 Nonpathogen - hypothetical protein TTC1686 1 None None None 46199235 Common - methionyl-tRNA synthetase TTC0931 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 46200237 Common - tungstate transport system permease protein TTC1935 64 COG4662 TupA, ABC-type tungstate transport system, periplasmic component Coenzyme metabolism 46199808 Nonpathogen - hypothetical protein TTC1506 1 None None None 46198561 Common - 5-methyltetrahydrofolate-homocysteine methyltransferase TTC0253 180 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 46200015 Common groES co-chaperonin GroES TTC1713 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 46199667 Common - hypothetical protein TTC1365 13 COG5428 COG5428, Uncharacterized conserved small protein Function unknown 46200095 Common - permease TTC1793 12 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 46199267 Common - glutamine synthetase TTC0965 231 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 46199357 Common soxZ soxZ TTC1055 34 None None None 46199832 Nonpathogen - hypothetical protein TTC1530 2 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 46198701 Nonpathogen - hypothetical protein TTC0393 1 None None None 46199815 Common - sugar-binding protein TTC1513 54 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 46198724 Common - tripartite transporter, large subunit TTC0416 123 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 46198679 Common - iron(III) dicitrate-binding protein TTC0371 125 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 46199932 Common - phosphoglucomutase TTC1630 237 COG0033 Pgm, Phosphoglucomutase Carbohydrate transport and metabolism 46198567 Common - hypothetical protein TTC0259 81 COG1692 COG1692, Uncharacterized protein conserved in bacteria Function unknown 46199216 Common - V-type sodium ATP synthase subunit I TTC0912 38 COG1269 NtpI, Archaeal/vacuolar-type H+-ATPase subunit I Energy production and conversion 46198871 Common - cell volume regulation protein CvrA TTC0563 75 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 46199780 Common - yqgf-Family protein TTC1478 122 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 46200112 Common - acetyltransferase TTC1810 4 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 46198621 Common - ferredoxin-nitrite reductase TTC0313 169 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 46199162 Nonpathogen pilA pilA TTC0858 1 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 46199557 Common - methyltransferase TTC1255 175 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 46199438 Common - phosphoenolpyruvate synthase TTC1136 234 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 46199521 Common - probable glycine C-acetyltransferase TTC1219 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 46200040 Common rplK 50S ribosomal protein L11 TTC1738 249 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 46199849 Common - 3-isopropylmalate dehydratase large subunit TTC1547 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 46199999 Common - enoyl-CoA hydratase TTC1697 180 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 46198587 Common - probable glycosyltransferase TTC0279 181 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 46200140 Nonpathogen - general secretion pathway protein G TTC1838 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 46199373 Common - ABC transporter ATP-binding protein TTC1071 220 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 46199637 Common ebsC ebsC protein TTC1335 122 COG2606 EbsC, Uncharacterized conserved protein Function unknown 46198362 Common - probable UDP-N-acetyl-D-mannosaminuronic acid transferase TTC0054 109 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 46200136 Common - tungsten-containing aldehyde ferredoxin oxidoreductase TTC1834 57 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 46199753 Common - pterin-4-alpha-carbinolamine dehydratase TTC1451 117 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 46199457 Common - phosphoribosylformylglycinamidine synthase TTC1155 235 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 46199877 Common - acyl-CoA dehydrogenase, short-chain specific TTC1575 168 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 46199711 Common - acetyl-coenzyme A carboxylase carboxyl transferase subunit beta TTC1409 201 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 46199733 Common - transposase TTC1431 12 COG5421 COG5421, Transposase DNA replication, recombination, and repair 46198554 Common - hypothetical protein TTC0246 20 COG3870 COG3870, Uncharacterized protein conserved in bacteria Function unknown 46198582 Nonpathogen - hypothetical protein TTC0274 1 COG3765 WzzB, Chain length determinant protein Cell envelope biogenesis, outer membrane 46199481 Nonpathogen - hypothetical protein TTC1179 1 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 46199103 Common - hypothetical protein TTC0797 111 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 46200013 Common - 6-carboxyhexanoate-CoA ligase TTC1711 140 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 46199990 Common - glucokinase TTC1688 14 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 46199332 Nonpathogen - ribosomal protein TTC1030 1 None None None 46198710 Common - hypothetical protein TTC0402 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 46199563 Common - osmotically inducible protein C TTC1261 76 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 46198761 Nonpathogen - hypothetical protein TTC0453 1 None None None 46200175 Common dprA competence protein dprA TTC1873 210 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 46199428 Common grpE grpE protein TTC1126 192 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 46199735 Nonpathogen - hypothetical protein TTC1433 5 None None None 46199687 Common - thioredoxin TTC1385 234 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 46198423 Common - homoserine dehydrogenase TTC0115 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 46198510 Common - glucose dehydrogenase [pyrroloquinoline-quinone] TTC0202 123 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 46198517 Nonpathogen - hypothetical protein TTC0209 4 None None None 46200049 Common - lipoyl synthase TTC1747 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 46199204 Common - zinc protease TTC0900 193 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 46198521 Common - soluble hydrogenase, small subunit TTC0213 153 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 46198696 Common - sensory transduction protein kinase TTC0388 23 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 46198535 Common - manganese-binding protein TTC0227 185 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 46199283 Nonpathogen - hypothetical protein TTC0981 4 None None None 46199963 Nonpathogen - hypothetical protein TTC1661 1 COG4856 COG4856, Uncharacterized protein conserved in bacteria Function unknown 46200209 Common - NADH-quinone oxidoreductase chain N TTC1907 185 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 46199036 Nonpathogen - hypothetical protein TTC0728 2 None None None 46198962 Nonpathogen - hypothetical protein TTC0654 1 None None None 46199868 Nonpathogen - hypothetical protein TTC1566 1 COG1295 Rbn, Predicted membrane protein Function unknown 46199789 Common - ABC transporter ATP-binding protein TTC1487 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 46199861 Common - ABC transporter ATP-binding protein TTC1559 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 46199329 Common - putative sugar kinase TTC1027 219 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 46198458 Common - glycine dehydrogenase subunit 1 TTC0150 172 COG0403 GcvP, Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain Amino acid transport and metabolism 46198659 Common - cell wall endopeptidase, family M23/M37 TTC0351 195 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 46199188 Common - acetyl-coenzyme A synthetase TTC0884 214 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 46199031 Common ftsA cell division protein ftsA TTC0723 198 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 46200184 Nonpathogen - hypothetical protein TTC1882 2 None None None 46198955 Common - hypothetical protein TTC0647 167 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 46198490 Common - enoyl-CoA hydratase TTC0182 178 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 46199254 Common - transporter TTC0952 104 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 46199697 Common - hypothetical protein TTC1395 15 COG1724 COG1724, Predicted periplasmic or secreted lipoprotein Cell motility and secretion 46198615 Common sat sulfate adenylyltransferase TTC0307 64 COG2046 MET3, ATP sulfurylase (sulfate adenylyltransferase) Inorganic ion transport and metabolism 46200235 Common vanW vancomycin B-type resistance protein vanW TTC1933 38 COG2720 COG2720, Uncharacterized vancomycin resistance protein Defense mechanisms 46199004 Common - hypothetical membrane associated protein TTC0696 78 COG2425 COG2425, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 46199085 Common - putative acyl-CoA dehydrogenase TTC0779 160 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 46199925 Common - putative lipase TTC1623 42 COG2179 COG2179, Predicted hydrolase of the HAD superfamily General function prediction only 46198927 Common - probable L-aspartate oxidase protein TTC0619 225 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 46199014 Common - competence protein F TTC0706 5 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 46200195 Nonpathogen - permease TTC1893 16 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 46199773 Common - phosphoglycolate phosphatase TTC1471 209 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 46200147 Common - general secretion pathway protein F TTC1845 140 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 46199339 Common ccmG ccmG protein TTC1037 163 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 46199827 Common - transporter TTC1525 137 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 46199571 Nonpathogen - hypothetical protein TTC1269 1 None None None 46198311 Common - hypothetical protein TTC0003 60 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 46199350 Nonpathogen - hypothetical protein TTC1048 1 COG3439 COG3439, Uncharacterized conserved protein Function unknown 46199320 Common - chorismate synthase TTC1018 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 46198778 Common kefC glutathione-regulated potassium-efflux system protein kefC TTC0470 131 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 46199243 Nonpathogen - hypothetical protein TTC0941 1 None None None 46200083 Common - permease TTC1781 24 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 46200004 Common - argininosuccinate lyase TTC1702 225 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 46198745 Common - hypothetical membrane associated protein TTC0437 15 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 46199604 Common - 30S ribosomal protein S11 TTC1302 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 46199722 Common - metal dependent phosphohydrolase TTC1420 33 COG1713 COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism Coenzyme metabolism 46199063 Common - hypothetical protein TTC0757 10 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 46199179 Common potB spermidine/putrescine transport system permease protein potB TTC0875 189 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 46199475 Common - putative oxidoreductase-like protein TTC1173 69 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 46199775 Common - muconate cycloisomerase TTC1473 64 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 46198930 Common - hypothetical protein TTC0622 105 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 46198945 Common - polyphosphate kinase TTC0637 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 46200075 Nonpathogen - hypothetical protein TTC1773 1 None None None 46199627 Common rplB 50S ribosomal protein L2 TTC1325 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 46198767 Common - phosphoribosylglycinamide formyltransferase TTC0459 220 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 46198384 Common - alpha-hemolysin TTC0076 183 COG0759 COG0759, Uncharacterized conserved protein Function unknown 46198733 Nonpathogen - hypothetical protein TTC0425 3 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 46199755 Nonpathogen - hypothetical protein TTC1453 1 None None None 46200214 Common - NADH-quinone oxidoreductase chain I TTC1912 194 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 46199905 Common comE competence factor comEC TTC1603 110 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 46199392 Common - succinate dehydrogenase flavoprotein subunit-like protein TTC1090 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 46198846 Common - 33 kDa chaperonin TTC0538 74 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 46198504 Nonpathogen - hypothetical protein TTC0196 1 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 46198831 Common - methyltransferase TTC0523 78 COG4121 COG4121, Uncharacterized conserved protein Function unknown 46200156 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase TTC1854 209 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 46199041 Common - membrane lipoprotein TTC0733 104 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 46198777 Common yebC hypothetical protein TTC0469 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 46198574 Nonpathogen - hypothetical protein TTC0266 6 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 46198330 Nonpathogen - hypothetical protein TTC0022 1 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 46198913 Common paaD phenylacetic acid degradation protein paaD TTC0605 53 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 46198791 Common - putative permease TTC0483 50 COG0730 COG0730, Predicted permeases General function prediction only 46198866 Nonpathogen - hypothetical protein TTC0558 1 COG0344 COG0344, Predicted membrane protein Function unknown 46200119 Nonpathogen - hypothetical protein TTC1817 3 None None None 46198827 Common - N-acylamino acid racemase TTC0519 147 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 46198786 Nonpathogen - hypothetical protein TTC0478 1 None None None 46199468 Common - hypothetical protein TTC1166 8 None None None 46198346 Common ruvB Holliday junction DNA helicase B TTC0038 243 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 46199973 Common - cytochrome c oxidase polypeptide I+III TTC1671 175 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 46198405 Common - alcohol dehydrogenase TTC0097 203 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 46199718 Common - pantoate-beta-alanine ligase TTC1416 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 46198318 Common - sugar ABC transporter, permease protein TTC0010 143 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 46199793 Common - anthranilate phosphoribosyltransferase TTC1491 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 46199955 Nonpathogen - hypothetical protein TTC1653 2 None None None 46199308 Common - N-acetylmuramoyl-L-alanine amidase TTC1006 178 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 46199076 Common - subunit II of C(O/B)3-type cytochrome c oxidase TTC0770 156 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 46199449 Common - hypothetical protein TTC1147 34 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 46198487 Nonpathogen - hypothetical protein TTC0179 1 None None None 46199291 Common - 3-dehydroquinate dehydratase TTC0989 169 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 46198771 Common - sensory transduction histidine kinase TTC0463 174 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 46198852 Nonpathogen - hypothetical protein TTC0544 1 None None None 46199546 Common - hypothetical protein TTC1244 88 COG1430 COG1430, Uncharacterized conserved protein Function unknown 46199620 Common rplN 50S ribosomal protein L14 TTC1318 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 161611244 Common rpmE 50S ribosomal protein L31 TTC0708 160 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 46199488 Common luxS S-ribosylhomocysteinase TTC1186 55 COG1854 LuxS, LuxS protein involved in autoinducer AI2 synthesis Signal transduction mechanisms 46200281 Nonpathogen - hypothetical protein TTC1979 2 COG2105 COG2105, Uncharacterized conserved protein Function unknown 46198528 Common livH branched-chain amino acid transport system permease protein livH TTC0220 127 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 46199463 Common - putative DNA repair and genetic recombination protein TTC1161 196 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 46199316 Nonpathogen pilN competence protein pilN TTC1014 2 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 46198861 Common - ornithine aminotransferase TTC0553 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 46198737 Nonpathogen - hypothetical membrane spanning protein TTC0429 9 None None None 46198711 Common - gamma-glutamyltranspeptidase TTC0403 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 46200188 Common - exopolyphosphatase family protein TTC1886 82 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 46199067 Nonpathogen - hypothetical protein TTC0761 19 None None None 46198774 Nonpathogen - hypothetical protein TTC0466 1 None None None 46198533 Common - probable mannitol-binding protein with frameshift TTC0225 69 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 46198934 Nonpathogen marR probable transcriptional regulator, marR family TTC0626 4 COG1846 MarR, Transcriptional regulators Transcription 46198784 Nonpathogen - hypothetical protein TTC0476 1 None None None 46198783 Nonpathogen ompH putative cationic outer membrane protein ompH TTC0475 2 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 46199317 Nonpathogen pilO competence protein pilO TTC1015 2 COG3167 PilO, Tfp pilus assembly protein PilO Cell motility and secretion / Intracellular trafficking and secretion 46198755 Common - prephenate dehydrogenase TTC0447 130 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 161611245 Common ileS isoleucyl-tRNA synthetase TTC0702 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 46199813 Nonpathogen - hypothetical protein TTC1511 1 None None None 46199058 Common - iron-sulfur binding reductase, putative TTC0752 149 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 46199800 Nonpathogen - hypothetical protein TTC1498 1 None None None 46199600 Common - hypothetical protein TTC1298 9 None None None 46200165 Common - hypothetical protein TTC1863 14 None None None 46200146 Common - putative ATPase TTC1844 224 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 46198480 Common - hypothetical protein TTC0172 43 COG4956 COG4956, Integral membrane protein (PIN domain superfamily) General function prediction only 46198838 Common rfaG lipopolysaccharide core biosynthesis protein rfaG TTC0530 159 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 46198726 Common - ATP-dependent protease La TTC0418 198 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 46198869 Common - phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase TTC0561 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 46198826 Common - chorismate synthase TTC0518 14 COG3375 COG3375, Uncharacterized conserved protein Function unknown 46200003 Common - argininosuccinate synthase TTC1701 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 46199717 Common pilT pili retraction protein pilT TTC1415 205 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 46199043 Nonpathogen - hypothetical protein TTC0735 2 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 46198525 Common - putative ABC transporter component TTC0217 204 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 46199352 Common - putative cytochrome c, sox a-like TTC1050 31 COG3258 COG3258, Cytochrome c Energy production and conversion 46199779 Common - 4-amino-4-deoxychorismate lyase TTC1477 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 46199911 Common - DNA polymerase III, beta chain TTC1609 208 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 46199074 Nonpathogen - cytochrome c oxidase polypeptide IIA TTC0768 1 None None None 46199825 Common - recombination factor protein RarA TTC1523 230 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 46199756 Common mutM formamidopyrimidine-DNA glycosylase mutM TTC1454 179 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 46199061 Common - methylenetetrahydrofolate dehydrogenase (NADP+)/methenyltetrahydrofolate cyclohydrolase TTC0755 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 46198841 Common - transcription-repair coupling factor TTC0533 221 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 46199053 Nonpathogen - hypothetical protein TTC0747 2 COG4371 COG4371, Predicted membrane protein Function unknown 46199589 Common malF maltose transport system permease protein malF TTC1287 140 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 46198435 Common glcF (S)-2-hydroxy-acid oxidase subunit glcF TTC0127 177 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 46198355 Common - 3-oxoacyl-[acyl-carrier protein] reductase TTC0047 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 46199934 Common - fosmidomycin resistance protein TTC1632 65 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 46199646 Nonpathogen - hypothetical protein TTC1344 1 None None None 46200216 Common - NADH-quinone oxidoreductase chain G TTC1914 195 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 46199172 Common - hypothetical protein TTC0868 18 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 46198475 Common - purine phosphoribosyltransferase TTC0167 30 COG2236 COG2236, Predicted phosphoribosyltransferases General function prediction only 46198418 Common - apolipoprotein N-acyltransferase TTC0110 163 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 46199720 Common - iojap protein family TTC1418 192 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 46198383 Common - probable membrane protein TTC0075 211 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 46198848 Common - hypothetical membrane spanning protein TTC0540 39 COG2738 COG2738, Predicted Zn-dependent protease General function prediction only 46199348 Common soxC sulfite dehydrogenase soxC precursor TTC1046 98 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 46199157 Common - thioredoxin reductase TTC0853 220 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 46199143 Common - hypothetical protein TTC0837 15 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 46199416 Nonpathogen - hypothetical protein TTC1114 1 COG3431 COG3431, Predicted membrane protein Function unknown 46199929 Common - trehalose/maltose-binding protein TTC1627 84 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 46199205 Common - zinc protease TTC0901 153 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 46198427 Nonpathogen - hypothetical protein TTC0119 1 None None None 46198555 Common carB carbamoyl phosphate synthase large subunit TTC0247 237 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 46198883 Nonpathogen - hypothetical protein TTC0575 2 None None None 46200172 Common - branched-chain amino acid aminotransferase TTC1870 213 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 46199287 Nonpathogen - hypothetical protein TTC0985 6 COG3580 COG3580, Uncharacterized protein conserved in bacteria Function unknown 46199185 Nonpathogen - methylmalonyl-CoA mutase TTC0881 1 None None None 46198397 Common - cytidylate kinase TTC0089 201 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 46198636 Common - glucose-binding protein TTC0328 78 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 46198989 Nonpathogen - hypothetical protein TTC0681 1 None None None 46199134 Common ftsI putative transpeptidase, cell division protein ftsI TTC0828 202 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 46199200 Common - DNA primase TTC0896 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 46199770 Common cinA competence-damage protein cinA TTC1468 209 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 46199259 Common - formyltetrahydrofolate deformylase TTC0957 211 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 46199089 Common - putative propionyl-CoA carboxylase beta chain TTC0783 212 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 46199411 Common - hypothetical protein TTC1109 130 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 46198499 Common - acetyl-CoA acetyltransferase TTC0191 180 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 46199943 Common - aspartate aminotransferase TTC1641 233 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 46199918 Common - phage shock protein A TTC1616 75 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 46198351 Common - alpha-aminodipate aminotransferase TTC0043 225 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 46198497 Common - superoxide dismutase [Mn] TTC0189 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 46200155 Nonpathogen - hypothetical protein TTC1853 1 None None None 46199280 Common - citrate synthase TTC0978 194 COG0372 GltA, Citrate synthase Energy production and conversion 46199336 Common - cytochrome complex Fe-S subunit, putative TTC1034 6 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 46200077 Common - ABC transporter permease protein TTC1775 28 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 46199941 Common - ferric uptake regulation protein TTC1639 132 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 46198985 Common - methylmalonyl-CoA mutase large subunit TTC0677 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 46198546 Common - acyl-CoA dehydrogenase, short-chain specific TTC0238 167 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 46199948 Nonpathogen - hypothetical protein TTC1646 1 None None None 46199307 Common - serine protease-like protein TTC1005 150 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 46199696 Nonpathogen - hypothetical protein TTC1394 1 COG1598 COG1598, Uncharacterized conserved protein Function unknown 46199246 Common - probable Fe/S oxidoreductase TTC0944 32 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 46199675 Common - cysteine desulfhydrase/selenocysteine lyase TTC1373 239 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 46198586 Nonpathogen - hypothetical protein TTC0278 1 None None None 46199652 Nonpathogen - hypothetical protein TTC1350 3 None None None 46199958 Common - methylenetetrahydrofolate reductase TTC1656 149 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 46198569 Common - large-conductance mechanosensitive channel TTC0261 142 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 46200042 Common rpsF 30S ribosomal protein S6 TTC1740 108 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 46200263 Common trkA zrk system potassium uptake protein trkA TTC1961 22 COG3400 COG3400, Uncharacterized protein conserved in bacteria Function unknown 46199261 Common - DNA mismatch repair enzyme (predicted ATPase) TTC0959 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 46199034 Common - hypothetical protein TTC0726 33 COG1839 COG1839, Uncharacterized conserved protein Function unknown 46199848 Common - 3-isopropylmalate dehydratase TTC1546 199 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 46199882 Common - transporter TTC1580 83 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 46198364 Common - thiamin-monophosphate kinase TTC0056 110 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 46198762 Common - hypothetical membrane spanning protein TTC0454 17 COG2862 COG2862, Predicted membrane protein Function unknown 46199451 Common - putative adenylosuccinate lyase protein TTC1149 237 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 46199560 Nonpathogen - thiosulfate sulfurtransferase TTC1258 5 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 46199841 Common - beta-ureidopropionase TTC1539 124 COG0388 COG0388, Predicted amidohydrolase General function prediction only 46198469 Nonpathogen - hypothetical protein TTC0161 2 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 46198892 Common degV probable degV protein TTC0584 33 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 46199683 Common - orotidine 5'-phosphate decarboxylase TTC1381 74 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 46199116 Common trkA potassium transporter peripheral membrane component TTC0810 168 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 46199425 Common clpB endopeptidase clp ATP-binding chain B, clpB TTC1123 228 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 46199168 Common - tryptophanyl-tRNA synthetase TTC0864 247 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 46199186 Common - methylmalonyl-CoA mutase TTC0882 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 46199783 Nonpathogen - hypothetical protein TTC1481 1 None None None 46199456 Common - hypothetical protein TTC1154 49 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 46198694 Nonpathogen - hypothetical protein TTC0386 1 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 46199920 Common - phosphoglycerate mutase TTC1618 188 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 46200070 Common - enoyl-CoA hydratase TTC1768 89 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 46198716 Common - O-acetyl-L-(homo)serine sulfhydrylase TTC0408 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 46199455 Common - phosphoribosylformylglycinamidine synthase TTC1153 232 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 46199490 Common - hypothetical protein TTC1188 23 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 46198730 Common - sensory transduction histidine kinase TTC0422 171 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 46199394 Common - succinate dehydrogenase membrane anchor subunit TTC1092 23 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 46200030 Common - hypothetical protein TTC1728 31 COG3872 COG3872, Predicted metal-dependent enzyme General function prediction only 46199292 Common - DNA gyrase subunit A TTC0990 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 46200053 Common - transporter TTC1751 58 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 46198994 Common - hypothetical protein TTC0686 18 COG4864 COG4864, Uncharacterized protein conserved in bacteria Function unknown 46199590 Common - maltose/maltodextrin-binding protein TTC1288 93 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 46200225 Common - hypothetical protein TTC1923 9 COG4712 COG4712, Uncharacterized protein conserved in bacteria Function unknown 46199281 Common moeB molybdopterin biosynthesis moeB protein TTC0979 214 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 46199409 Common - hypothetical protein TTC1107 140 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 46199238 Common - ABC transporter periplasmic binding protein TTC0934 100 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 46200090 Common - ribonuclease HII TTC1788 207 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 46199803 Common - oligoendopeptidase F TTC1501 87 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 46200098 Common - dihydroneopterin aldolase TTC1796 31 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 46199669 Nonpathogen - hypothetical protein TTC1367 1 COG3462 COG3462, Predicted membrane protein Function unknown 46198706 Common - transcriptional repressor TTC0398 110 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 46199618 Common rplE 50S ribosomal protein L5 TTC1316 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 46199497 Common - DNA pantothenate metabolism flavoprotein TTC1195 228 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 46200067 Common - transporter TTC1765 94 COG1738 COG1738, Uncharacterized conserved protein Function unknown 46199839 Common - hypothetical protein TTC1537 5 None None None 46199548 Common - hypothetical protein TTC1246 15 COG2331 COG2331, Uncharacterized protein conserved in bacteria Function unknown 46199125 Common - putative transpeptidase TTC0819 202 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 46199810 Common - tpl protein TTC1508 58 COG1774 COG1774, Uncharacterized homolog of PSP1 Function unknown 46200233 Common - DNA topoisomerase I TTC1931 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 46198680 Common - serine protease TTC0372 141 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 46198444 Nonpathogen - hypothetical cytosolic protein TTC0136 10 COG2152 COG2152, Predicted glycosylase Carbohydrate transport and metabolism 46199554 Common - acid phosphatase TTC1252 25 COG1409 Icc, Predicted phosphohydrolases General function prediction only 46199791 Common - ABC transporter ATP-binding protein TTC1489 172 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 46199573 Common - dipeptide-binding protein TTC1271 175 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 46199219 Nonpathogen - hypothetical protein TTC0915 2 None None None 46199369 Common - hypothetical protein TTC1067 21 COG5502 COG5502, Uncharacterized conserved protein Function unknown 46200105 Nonpathogen - 5-formyltetrahydrofolate cyclo-ligase TTC1803 19 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 46198668 Common hisS histidyl-tRNA synthetase TTC0360 248 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 46199359 Common - thioredoxin TTC1057 25 COG2143 COG2143, Thioredoxin-related protein Posttranslational modification, protein turnover, chaperones 46198692 Nonpathogen - hypothetical protein TTC0384 1 None None None 46198313 Common - hypothetical protein TTC0005 115 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 46199532 Common - serine/threonine protein kinase TTC1230 156 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 46200085 Common - transporter TTC1783 66 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 46200186 Common - hydrolase (HAD superfamily) TTC1884 11 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 46199951 Common - hypothetical protein TTC1649 58 COG1993 COG1993, Uncharacterized conserved protein Function unknown 46198675 Nonpathogen - hypothetical protein TTC0367 2 None None None 46200024 Common - multidrug resistance protein 2 TTC1722 74 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 46200005 Common - acetyltransferase TTC1703 105 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 46199887 Common - putative amidotransferase TTC1585 149 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 46198366 Nonpathogen - hypothetical protein TTC0058 2 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 46198977 Common rplS 50S ribosomal protein L19 TTC0669 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 46198793 Common - hydroxyacylglutathione hydrolase TTC0485 212 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 46199158 Nonpathogen - prepilin-like protein TTC0854 1 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 46199591 Common - hypothetical protein TTC1289 13 COG1723 COG1723, Uncharacterized conserved protein Function unknown 46199761 Common - L-fuculose phosphate aldolase TTC1459 115 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 46199362 Common - ABC transporter substrate-binding protein TTC1060 15 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 46199916 Common - 1-deoxy-D-xylulose-5-phosphate synthase TTC1614 227 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 46198752 Nonpathogen - hypothetical protein TTC0444 3 None None None 46198644 Common - branched amino acid transport system permease TTC0336 16 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 46198721 Common - endo-type 6-aminohexanoate oligomer hydrolase TTC0413 48 COG3191 DmpA, L-aminopeptidase/D-esterase Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 46198577 Common - nucleotidyltransferase TTC0269 9 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 46199597 Nonpathogen - hypothetical protein TTC1295 3 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 46199249 Common - putative glycosyltransferase TTC0947 113 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 46198590 Common - asparagine synthetase [glutamine-hydrolyzing] TTC0282 7 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 46199896 Common pheS phenylalanyl-tRNA synthetase subunit alpha TTC1594 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 46198685 Common - acriflavin resistance protein B TTC0377 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 46198921 Common - sugar ABC transporter, permease protein TTC0613 140 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 46199195 Nonpathogen - hypothetical protein TTC0891 2 None None None 46199503 Common - hypothetical protein TTC1201 20 COG4365 COG4365, Uncharacterized protein conserved in bacteria Function unknown 46199325 Nonpathogen - hypothetical protein TTC1023 2 COG3296 COG3296, Uncharacterized protein conserved in bacteria Function unknown 46199975 Common - protoheme IX farnesyltransferase TTC1673 180 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 46198379 Common - probable ABC transport protein, ATP-binding component TTC0071 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 46199965 Common - methionyl-tRNA formyltransferase TTC1663 220 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 46200045 Common rplI 50S ribosomal protein L9 TTC1743 216 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 46200194 Common - endonuclease III TTC1892 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 46199382 Common - phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase TTC1080 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 46199048 Nonpathogen - hypothetical conserved membrane spanning protein TTC0742 2 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 46199511 Common - putative dehydrogenase TTC1209 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 46198800 Nonpathogen - hypothetical protein TTC0492 1 None None None 46199639 Nonpathogen - hypothetical protein TTC1337 1 None None None 46198953 Nonpathogen - hypothetical protein TTC0645 1 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 46198451 Common - hypothetical cytosolic protein TTC0143 159 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 46198742 Nonpathogen - hypothetical cytosolic protein TTC0434 2 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 46198811 Common - membrane metalloprotease TTC0503 210 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 46199562 Nonpathogen - hypothetical protein TTC1260 8 COG1579 COG1579, Zn-ribbon protein, possibly nucleic acid-binding General function prediction only 46198398 Nonpathogen - hypothetical protein TTC0090 2 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 46200269 Nonpathogen - hypothetical protein TTC1967 1 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 46199236 Common - ribose 5-phosphate isomerase TTC0932 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 46199997 Common - hypothetical protein TTC1695 113 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 46199936 Common - inosine-5'-monophosphate dehydrogenase TTC1634 135 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 46200265 Common - lipoprotein signal peptidase TTC1963 8 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 46198328 Common - bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase TTC0020 191 COG2876 AroA, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 46199389 Common aspC aspartyl-tRNA synthetase TTC1087 249 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 46199858 Nonpathogen - hypothetical protein TTC1556 1 None None None 46198653 Common - bifunctional preprotein translocase subunit SecD/SecF TTC0345 214 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 46199702 Common - hypothetical protein TTC1400 18 None None None 46198875 Common - hypothetical cytosolic protein TTC0567 12 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 46199170 Common - 3-isopropylmalate dehydratase TTC0866 209 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 46200014 Common - 23S rRNA methyltransferase TTC1712 199 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 46200200 Common - ribulose-phosphate 3-epimerase TTC1898 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 46199002 Common - ADP-ribosylglycohydrolase TTC0694 79 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 46198907 Common livM branched-chain amino acid transport system permease protein livM/branched-chain amino acid transport ATP-binding protein livG TTC0599 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 46199476 Common - hypothetical protein TTC1174 7 None None None 46199091 Common - DNA-dependent DNA polymerase beta chain TTC0785 80 COG1796 POL4, DNA polymerase IV (family X) DNA replication, recombination, and repair 46199851 Nonpathogen - hypothetical protein TTC1549 2 COG1724 COG1724, Predicted periplasmic or secreted lipoprotein Cell motility and secretion 46198520 Nonpathogen - hypothetical protein TTC0212 1 None None None 46198992 Common phoH phoH protein TTC0684 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 46199221 Common - metal dependent hydrolase TTC0917 114 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 46198339 Nonpathogen - hypothetical protein TTC0031 1 None None None 46198807 Common - 16S rRNA m(5)C 967 methyltransferase TTC0499 202 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 46198809 Nonpathogen - hypothetical protein TTC0501 1 None None None 46199830 Nonpathogen - hypothetical protein TTC1528 2 None None None 46198599 Common - phosphoglucomutase/phosphomannomutase TTC0291 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 46199686 Common plsX fatty acid/phospholipid synthesis protein TTC1384 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 46199447 Common - hypothetical protein TTC1145 155 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 46199104 Common - putative excisionase TTC0798 31 None None None 46199744 Common - transcriptional regulatory protein TTC1442 15 COG1694 MazG, Predicted pyrophosphatase General function prediction only 46198915 Nonpathogen paaB phenylacetic acid degradation protein paaB TTC0607 2 COG3460 COG3460, Uncharacterized enzyme of phenylacetate metabolism Secondary metabolites biosynthesis, transport, and catabolism 46199653 Common - hypothetical protein TTC1351 108 COG0432 COG0432, Uncharacterized conserved protein Function unknown 46200240 Common - L-asparaginase II TTC1938 46 COG4448 AnsA, L-asparaginase II Amino acid transport and metabolism 46200039 Common - transcription factor TTC1737 215 COG0250 NusG, Transcription antiterminator Transcription 46199400 Common - putative phosphoribosyl transferase TTC1098 63 COG1926 COG1926, Predicted phosphoribosyltransferases General function prediction only 46198638 Common - acetyl-CoA acetyltransferase TTC0330 185 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 46199274 Common dppB dipeptide transport system permease protein dppB TTC0972 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 46199344 Nonpathogen - heme exporter protein B TTC1042 7 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 46199621 Common rpsQ 30S ribosomal protein S17 TTC1319 230 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 46198719 Common - dehydrogenase family protein (alcohol) TTC0411 123 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 46200109 Nonpathogen - hypothetical protein TTC1807 23 COG2266 COG2266, GTP:adenosylcobinamide-phosphate guanylyltransferase Coenzyme metabolism 46200167 Common hisZ ATP phosphoribosyltransferase regulatory subunit TTC1865 135 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 46199746 Nonpathogen - hypothetical protein TTC1444 1 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 46199630 Common rplC 50S ribosomal protein L3 TTC1328 235 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 46199985 Nonpathogen - hypothetical protein TTC1683 1 None None None 46198603 Common - mrp protein TTC0295 234 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 46198919 Common - sugar transport ATP-binding protein TTC0611 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 46199072 Nonpathogen - probable gliding protein TTC0766 11 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 46198843 Common - 3-ketoacyl-CoA thiolase TTC0535 187 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 46198969 Nonpathogen - hypothetical protein TTC0661 1 None None None 46200001 Common - dihydrolipoamide succinyltransferase TTC1699 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 46199045 Nonpathogen - hypothetical protein TTC0737 2 None None None 46199823 Common - membrane GTPase TTC1521 89 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 46199483 Common - membrane dipeptidase TTC1181 93 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 46199152 Common - acetyltransferase TTC0848 71 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 46198387 Common - long-chain-fatty-acid-CoA ligase TTC0079 211 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 46199466 Nonpathogen - hypothetical protein TTC1164 2 None None None 46198645 Common livH branched-chain amino acid transport system permease protein livH TTC0337 144 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 46198334 Common - cehydrogenase TTC0026 45 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 46199729 Nonpathogen - hypothetical protein TTC1427 4 COG4632 EpsL, Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Carbohydrate transport and metabolism 46198548 Common - 4-hydroxybenzoate octaprenyltransferase TTC0240 74 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 46198888 Nonpathogen - hypothetical protein TTC0580 1 None None None 46198910 Common - phenylacetyl-CoA ligase TTC0602 119 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 46200267 Common - membrane protein TTC1965 11 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 46199970 Nonpathogen - hypothetical protein TTC1668 2 None None None 46199605 Common rpsM 30S ribosomal protein S13 TTC1303 246 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 46199623 Common rplP 50S ribosomal protein L16 TTC1321 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 46200258 Common - phosphoglycerate mutase/fructose-2,6-bisphosphatase TTC1956 38 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 46199909 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA TTC1607 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 46200115 Common - serine-pyruvate aminotransferase TTC1813 163 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 46199648 Nonpathogen - hypothetical protein TTC1346 2 COG4715 COG4715, Uncharacterized conserved protein Function unknown 46199110 Nonpathogen - hypothetical protein TTC0804 1 None None None 46199969 Nonpathogen - hypothetical protein TTC1667 1 None None None 46198960 Nonpathogen - hypothetical protein TTC0652 2 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 46198735 Common pyrB aspartate carbamoyltransferase catalytic subunit TTC0427 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 46199323 Common - putative rRNA methyl transferase TTC1021 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 46198477 Common - succinyl-CoA synthetase alpha chain TTC0169 212 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 46198863 Nonpathogen - hypothetical protein TTC0555 6 COG1355 COG1355, Predicted dioxygenase General function prediction only 46199471 Common - probable DNA-binding protein TTC1169 70 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 46199314 Common - homoisocitrate dehydrogenase TTC1012 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 46198904 Common - homoprotocatechuate 2,3-dioxygenase TTC0596 36 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 46199183 Common minD cell division inhibitor minD TTC0879 147 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 46199983 Nonpathogen - hypothetical protein TTC1681 5 None None None 46199798 Nonpathogen - tetratricopeptide repeat family protein TTC1496 3 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 46199319 Common pilQ competence protein pilQ TTC1017 142 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 46198788 Common - membrane metalloprotease TTC0480 19 None None None 46199378 Nonpathogen - hypothetical protein TTC1076 2 COG1808 COG1808, Predicted membrane protein Function unknown 46198523 Nonpathogen - hypothetical protein TTC0215 1 None None None 46198798 Common - hypothetical protein TTC0490 71 COG2718 COG2718, Uncharacterized conserved protein Function unknown 46199285 Common - putative acyltransferase TTC0983 201 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 46200285 Common lytB lytB protein TTC1983 187 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 46199056 Common - hypothetical membrane spanning protein TTC0750 39 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 46199962 Common - hypothetical membrane spanning protein TTC1660 67 COG1624 COG1624, Uncharacterized conserved protein Function unknown 46199248 Common - uracil phosphoribosyltransferase TTC0946 163 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 46198836 Common rfbF dTDP-rhamnosyl transferase rfbF TTC0528 88 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 46198697 Common lepA GTP-binding protein LepA TTC0389 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 46199672 Common - laccase TTC1370 132 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 46199626 Common rpsS 30S ribosomal protein S19 TTC1324 248 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 46200144 Nonpathogen - hypothetical protein TTC1842 1 COG4967 PilV, Tfp pilus assembly protein PilV Cell motility and secretion / Intracellular trafficking and secretion 46198456 Common - aminomethyltransferase TTC0148 179 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 46199263 Common - probable sulfite reductase TTC0961 76 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 46200132 Common marR transcriptional regulators, marR/emrR family TTC1830 30 COG1846 MarR, Transcriptional regulators Transcription 46199995 Common - putative Rossmann fold nucleotide-binding protein TTC1693 49 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 46199846 Nonpathogen - hypothetical protein TTC1544 1 None None None 46199862 Common - hypothetical protein TTC1560 130 COG2096 COG2096, Uncharacterized conserved protein Function unknown 46198958 Common - probable transmembrane protein TTC0650 78 COG1511 COG1511, Predicted membrane protein Function unknown 46199785 Common glnQ glutamine transport ATP-binding protein glnQ TTC1483 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 46199121 Common - phosphatidylserine decarboxylase TTC0815 69 COG3001 COG3001, Uncharacterized protein conserved in bacteria Function unknown 46198341 Nonpathogen - hypothetical protein TTC0033 5 COG3255 COG3255, Putative sterol carrier protein Lipid metabolism 46199018 Common mraZ hypothetical protein TTC0710 128 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 46198348 Common - ribosomal large subunit pseudouridine synthase D TTC0040 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 46198690 Common - probable hemolysin-related protein/CBS domain containing protein TTC0382 218 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 46198570 Nonpathogen - hypothetical protein TTC0262 2 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 46198420 Common - iron-sulfur cluster-binding protein TTC0112 127 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 46198540 Common - uroporphyrinogen decarboxylase TTC0232 184 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 46199787 Common - isocitrate lyase TTC1485 128 COG2224 AceA, Isocitrate lyase Energy production and conversion 46199845 Common - ribosomal protein S6 modification protein TTC1543 151 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 46199460 Common - predicted GTPase TTC1158 83 COG1159 Era, GTPase General function prediction only 46200139 Nonpathogen - hypothetical membrane spanning protein TTC1837 1 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 46198781 Common - S-adenosylmethionine decarboxylase proenzyme TTC0473 25 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 46199681 Nonpathogen - hypothetical protein TTC1379 1 None None None 46198714 Common - hypothetical protein TTC0406 93 COG1801 COG1801, Uncharacterized conserved protein Function unknown 46199543 Common - acylamino-acid-releasing enzyme TTC1241 109 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 46198613 Common - quinone oxidoreductase TTC0305 87 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 46200255 Common - putative phosphohydrolase TTC1953 9 COG2129 COG2129, Predicted phosphoesterases, related to the Icc protein General function prediction only 46198894 Common - D-3-phosphoglycerate dehydrogenase TTC0586 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 46199453 Common - phosphoribosylamidoimidazole-succinocarboxamide synthase TTC1151 193 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 46198463 Common - thiosulfate reductase precursor TTC0155 184 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 46198557 Common - trigger factor, ppiase TTC0249 211 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 46199354 Common soxB sulfur oxidation protein soxB TTC1052 89 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 46199166 Common - hypothetical protein TTC0862 26 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 46199087 Common - electron transfer flavoprotein alpha-subunit TTC0781 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 46198381 Common - methyltransferase TTC0073 213 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 46198796 Common tlpA thiol:disulfide interchange protein tlpA TTC0488 161 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 46198802 Nonpathogen - putative Zn-dependent hydrolase (beta-lactamase superfamily) TTC0494 11 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 46199181 Common rodA rod shape-determining protein rodA TTC0877 205 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 46199399 Common - hypothetical protein TTC1097 51 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 46198815 Common - uridylate kinase TTC0507 246 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 46199432 Common - putative protease IV transmembrane protein TTC1130 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 46200275 Common - cbs domain proteins TTC1973 153 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 46198512 Common - tRNA delta(2)-isopentenylpyrophosphate transferase TTC0204 213 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 46199523 Nonpathogen - hypothetical protein TTC1221 1 None None None 46198987 Common - lysyl-tRNA synthetase TTC0679 237 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 46199133 Nonpathogen - hypothetical protein TTC0827 1 None None None 46198429 Nonpathogen - 2-phosphoglycerate kinase TTC0121 14 COG2074 COG2074, 2-phosphoglycerate kinase Carbohydrate transport and metabolism 46199499 Common - guanylate kinase TTC1197 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 46198408 Common appC oligopeptide transport system permease protein appC TTC0100 218 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 46200279 Common - glucose-1-phosphate adenylyltransferase TTC1977 19 COG0778 NfnB, Nitroreductase Energy production and conversion 46200191 Common - prolyl-tRNA synthetase TTC1889 239 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 46198759 Common - hypothetical cytosolic protein TTC0451 22 COG1427 COG1427, Predicted periplasmic solute-binding protein General function prediction only 46198951 Common - two-component response regulator TTC0643 212 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 46200183 Common - transposase TTC1881 14 COG5421 COG5421, Transposase DNA replication, recombination, and repair 46200170 Nonpathogen - hypothetical protein TTC1868 1 None None None 46199567 Common sfuB iron(III)-transport system permease protein sfuB TTC1265 174 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 46198757 Common - probable lactoylglutathione lyase TTC0449 44 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 46198538 Common - protoporphyrinogen oxidase TTC0230 59 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 46199441 Common - two-component system histidine kinase TTC1139 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 46199673 Common - copper-exporting ATPase TTC1371 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 46198357 Common - 3-oxoacyl-[acyl-carrier-protein] synthase III TTC0049 224 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 46199694 Nonpathogen - hypothetical protein TTC1392 1 None None None 46198495 Common - hypothetical membrane spanning protein TTC0187 20 COG5322 COG5322, Predicted dehydrogenase General function prediction only 46198564 Nonpathogen - hypothetical protein TTC0256 7 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 46198353 Common - 3-oxoacyl-[acyl-carrier-protein] synthase TTC0045 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 46199945 Common - putative tetratricopeptide repeat family protein TTC1643 21 None None None 46199371 Common - putative dehydratase TTC1069 133 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 46200153 Common phoU phosphate transport system protein phoU TTC1851 198 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 46198479 Nonpathogen - hypothetical protein TTC0171 11 COG1568 COG1568, Predicted methyltransferases General function prediction only 46199328 Common - hypothetical protein TTC1026 152 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 46198632 Common exbD putative biopolymer transport exbD protein TTC0324 11 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 46198983 Common - hypothetical protein TTC0675 27 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 46199207 Nonpathogen - hypothetical protein TTC0903 1 None None None 46198885 Common - probable transposase TTC0577 40 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 46198936 Nonpathogen - hypothetical protein TTC0628 13 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 46198584 Common - second mannosyl transferase TTC0276 73 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 46198442 Common - export-related chaperone TTC0134 130 COG0073 ARC1, EMAP domain General function prediction only 46199737 Nonpathogen - hypothetical protein TTC1435 2 COG1433 COG1433, Uncharacterized conserved protein Function unknown 46199334 Nonpathogen - hypothetical protein TTC1032 1 None None None 46199309 Common - hypothetical protein TTC1007 84 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 46198887 Common - hypothetical protein TTC0579 11 None None None 46198315 Common - hypothetical protein TTC0007 39 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 46198620 Common hemD uroporphyrinogen-III synthase TTC0312 16 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 46200079 Common rplJ 50S ribosomal protein L10 TTC1777 215 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 46200107 Nonpathogen - hypothetical protein TTC1805 1 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 46198677 Nonpathogen - hypothetical protein TTC0369 2 None None None 46198388 Common livH branched-chain amino acid transport system permease protein livH TTC0080 128 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 46200181 Nonpathogen - hypothetical cytosolic protein TTC1879 11 COG0433 COG0433, Predicted ATPase General function prediction only 46199026 Common ftsW cell division protein, ftsW/rodA/spove family TTC0718 27 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 46198990 Nonpathogen - hypothetical protein TTC0682 1 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 46199889 Nonpathogen - hypothetical protein TTC1587 1 None None None 46199763 Common rpoB DNA-directed RNA polymerase subunit beta TTC1461 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 46199890 Common - DNA polymerase III holoenzyme tau subunit TTC1588 244 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 46199595 Common - redox-sensing transcriptional repressor Rex TTC1293 56 COG2344 COG2344, AT-rich DNA-binding protein General function prediction only 46198431 Common - coproporphyrinogen oxidase, anaerobic TTC0123 213 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 46200026 Common pstA phosphate transport system permease protein pstA TTC1724 227 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 46200055 Common - dihydrolipoamide dehydrogenase TTC1753 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 46199758 Common - thiamine-binding protein TTC1456 77 COG4143 TbpA, ABC-type thiamine transport system, periplasmic component Coenzyme metabolism 46199126 Nonpathogen - response regulator TTC0820 2 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 46200210 Common - NADH-quinone oxidoreductase chain M TTC1908 203 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 46200011 Common - phosphoenolpyruvate carboxykinase TTC1709 98 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 46199175 Common - dihydroxy-acid dehydratase TTC0871 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 46199899 Common pfkA 6-phosphofructokinase TTC1597 160 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 46199977 Common - uracil permease TTC1675 117 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 46199444 Common hemA glutamyl-tRNA reductase TTC1142 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 46200223 Common ksgA dimethyladenosine transferase TTC1921 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 46198896 Nonpathogen - mannosyl-3-phosphogylcerate synthase TTC0588 5 None None None 46198704 Common - hypothetical protein TTC0396 137 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 46200122 Nonpathogen - cyanophycinase TTC1820 1 COG4242 CphB, Cyanophycinase and related exopeptidases Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism 46199138 Nonpathogen - hypothetical protein TTC0832 1 None None None 46198395 Common - cysteine desulfhydrase/selenocysteine lyase TTC0087 234 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 46200047 Common - corticosteroid 11-beta-dehydrogenase TTC1745 229 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 46199396 Common - ABC transporter substrate-binding protein TTC1094 18 COG1470 COG1470, Predicted membrane protein Function unknown 46200061 Nonpathogen - hypothetical protein TTC1759 2 None None None 46199346 Common ccdA cytochrome C-type biogenesis protein ccdA TTC1044 57 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 46199541 Nonpathogen - hypothetical protein TTC1239 1 None None None 46198723 Common - tripartite transporter, small subunit TTC0415 58 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 46199304 Common - hypothetical protein TTC1002 53 COG1556 COG1556, Uncharacterized conserved protein Function unknown 46199211 Common - V-type ATP synthase subunit A TTC0907 247 COG1155 NtpA, Archaeal/vacuolar-type H+-ATPase subunit A Energy production and conversion 46200159 Common - translation initiation inhibitor TTC1857 190 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 46199805 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase ubiE TTC1503 223 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 46198508 Common - hypothetical protein TTC0200 6 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 46200129 Nonpathogen - hypothetical protein TTC1827 1 None None None 46199742 Nonpathogen - hypothetical protein TTC1440 1 COG2383 COG2383, Uncharacterized conserved protein Function unknown 46200152 Nonpathogen phoB phosphate regulon transcriptional regulatory protein phoB TTC1850 8 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 46200028 Common - phosphate-binding protein TTC1726 150 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 46199251 Common - membrane-integral protein, putative transporter TTC0949 135 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 46199299 Common - two-component response regulator TTC0997 213 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 46199837 Common - A/G-specific adenine DNA glycosylase TTC1535 232 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 46199633 Common - elongation factor G TTC1331 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 46199819 Common folE GTP cyclohydrolase I TTC1517 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 46199051 Common - glycosyltransferase TTC0745 22 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 46198501 Common - outer membrane protein TTC0193 56 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 46199434 Common - arginase TTC1132 93 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 46198728 Common - ABC transporter ATP-binding protein (taurine) TTC0420 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 46199131 Common - maf protein TTC0825 193 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 46198873 Common - quaternary ammonium compound-resistance protein TTC0565 127 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 46199478 Common mesJ putative cell cycle protein mesJ-like protein TTC1176 228 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 46198794 Common - glutaredoxin-like protein TTC0486 87 COG3634 AhpF, Alkyl hydroperoxide reductase, large subunit Posttranslational modification, protein turnover, chaperones 46200092 Common - C4-dicarboxylate-binding protein TTC1790 91 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 46198559 Common clpX ATP-dependent protease ATP-binding subunit TTC0251 234 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 46198595 Common wbpB lipopolysaccaride biosynthesis protein wbpB TTC0287 89 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 46199902 Common - Inorganic pyrophosphatase TTC1600 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 46200016 Common groEL chaperonin GroEL TTC1714 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 46199662 Common - transcriptional regulatory protein TTC1360 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 46198625 Common thiG thiazole synthase TTC0317 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 46199217 Nonpathogen - V-type ATPase subunit TTC0913 1 None None None 46200231 Common - N-(5'-phosphoribosyl)anthranilate isomerase TTC1929 149 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 46199165 Nonpathogen - hypothetical protein TTC0861 1 None None None 46199715 Common - hypothetical protein TTC1413 15 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 46198411 Common acuB acetoin utilization acuB protein TTC0103 205 COG0517 COG0517, FOG: CBS domain General function prediction only 46199223 Common - acetyl-coenzyme A synthetase TTC0919 212 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 46199552 Common - adenine phosphoribosyltransferase TTC1250 22 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 46199655 Common - mechanosensitive ion channel TTC1353 194 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 46198999 Common - phosphoglucosamine mutase/phosphoacetylglucosamine mutase/phosphomannomutase TTC0691 236 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 46199632 Common - elongation factor Tu TTC1330 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 46199009 Common - putative translaldolase TTC0701 176 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 46200242 Nonpathogen - putative glycolate oxidase subunit E TTC1940 2 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 46199000 Common - hypothetical protein TTC0692 64 COG1432 COG1432, Uncharacterized conserved protein Function unknown 46199872 Common - cytochrome c TTC1570 66 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 46199093 Nonpathogen - hypothetical protein TTC0787 1 None None None 46198917 Common tetR transcriptional regulator, tetR family TTC0609 85 COG1309 AcrR, Transcriptional regulator Transcription 46200088 Common - molybdopterin oxidoreductase TTC1786 181 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 46198601 Nonpathogen - hypothetical protein TTC0293 1 None None None 46198454 Nonpathogen - hypothetical protein TTC0146 1 COG2380 COG2380, Uncharacterized protein conserved in bacteria Function unknown 46199149 Common - ABC transporter ATP-binding protein TTC0843 249 COG4586 COG4586, ABC-type uncharacterized transport system, ATPase component General function prediction only 46198482 Common clpA ATP-dependent clp protease ATP-binding subunit clpA TTC0174 223 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 46199407 Common - hypothetical protein TTC1105 26 None None None 46199820 Common - ferripyochelin binding protein TTC1518 116 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 46199501 Common - putative methylated-DNA-protein-cysteine methyltransferase TTC1199 202 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 46199922 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B TTC1620 213 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 46198449 Nonpathogen - hypothetical protein TTC0141 1 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 46198670 Nonpathogen - hypothetical protein TTC0362 1 None None None 46199704 Nonpathogen - hypothetical protein TTC1402 11 None None None 46199569 Common truA tRNA pseudouridine synthase A TTC1267 232 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 46200133 Nonpathogen - hypothetical membrane spanning protein TTC1831 1 None None None 46198853 Common - hypothetical protein TTC0545 4 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 46198321 Common - hypothetical protein TTC0013 43 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 46199380 Common - hypothetical protein TTC1078 5 None None None 46199096 Nonpathogen - hypothetical protein TTC0790 1 None None None 46199607 Common - bacterial protein translation initiation factor 1 (IF-1) TTC1305 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 46198531 Nonpathogen - hypothetical protein TTC0223 1 None None None 46198923 Nonpathogen - sugar-binding protein TTC0615 10 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 46199967 Common - hypothetical cytosolic protein TTC1665 96 COG0391 COG0391, Uncharacterized conserved protein Function unknown 46199191 Common secA preprotein translocase subunit SecA TTC0887 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 46199534 Nonpathogen - hypothetical protein TTC1232 2 None None None 46200196 Common moeA molybdopterin biosynthesis moeA protein TTC1894 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 46200249 Common - molybdopterin (MPT) converting factor, subunit 2 TTC1947 158 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 46199387 Common - hypothetical membrane associated protein TTC1085 10 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 46198651 Common - hypothetical protein TTC0343 55 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 46199230 Nonpathogen - hypothetical protein TTC0926 2 None None None 46199198 Nonpathogen - hypothetical protein TTC0894 2 None None None 46198336 Nonpathogen - hypothetical protein TTC0028 2 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 46200202 Nonpathogen - hypothetical protein TTC1900 3 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 46198813 Common - phosphatidate cytidylyltransferase TTC0505 214 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 46199197 Common - probable ATP-dependent helicase lhr TTC0893 158 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 46199960 Nonpathogen - hypothetical protein TTC1658 1 None None None 46198740 Common pmbA pmbA protein TTC0432 163 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 46198687 Common - hypothetical protein TTC0379 10 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 46198358 Common rpmF 50S ribosomal protein L32 TTC0050 80 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 46199252 Common - hypothetical protein TTC0950 41 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 46200273 Nonpathogen - hypothetical protein TTC1971 2 COG3180 AbrB, Putative ammonia monooxygenase General function prediction only 46199679 Common - hypothetical cytosolic protein TTC1377 29 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 46199013 Common - hypothetical protein TTC0705 35 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 46199924 Common pilF ATP-binding motif-containing protein pilF TTC1622 204 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 46200151 Common phoB phosphate regulon transcriptional regulatory protein phoB TTC1849 210 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 46198551 Common - fibronectin/fibrinogen-binding protein TTC0243 81 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 46199947 Common - hypothetical protein TTC1645 72 COG1912 COG1912, Uncharacterized conserved protein Function unknown 46199545 Common - probable thymidylate kinase TTC1243 234 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 46200277 Common - ATP-dependent protease La TTC1975 116 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 46199321 Common - shikimate kinase TTC1019 197 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 46199119 Common - hypothetical protein TTC0813 49 COG2313 IndA, Uncharacterized enzyme involved in pigment biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 46198450 Common - hypothetical membrane spanning protein TTC0142 28 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 46198573 Common hslV ATP-dependent protease peptidase subunit TTC0265 155 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 46199201 Common - 4-alpha-glucanotransferase TTC0897 120 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 46199430 Common ftsH cell division protein ftsH TTC1128 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 46199429 Common dnaK chaperone protein dnaK TTC1127 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 46198695 Common - L-serine dehydratase TTC0387 107 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 46199688 Common - S1 domain protein TTC1386 169 COG1098 VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) Translation, ribosomal structure and biogenesis 46198566 Nonpathogen - hypothetical protein TTC0258 2 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 46199084 Common - sensory transduction histidine kinase TTC0778 222 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 46200283 Nonpathogen - tetratricopeptide repeat family protein TTC1981 1 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 46199284 Common - endonuclease V TTC0982 73 COG1515 Nfi, Deoxyinosine 3'endonuclease (endonuclease V) DNA replication, recombination, and repair 46199415 Common - hypothetical protein TTC1113 22 COG0490 COG0490, Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels Inorganic ion transport and metabolism 46199303 Common - iron-sulfur cluster-binding protein TTC1001 94 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 46198634 Common - sugar transport system permease protein TTC0326 156 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 46198981 Common rpsP 30S ribosomal protein S16 TTC0673 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 46199146 Common - hypothetical protein TTC0840 51 COG2361 COG2361, Uncharacterized conserved protein Function unknown 46199030 Nonpathogen ftsQ cell division protein ftsQ TTC0722 2 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 46198368 Common - putative histidinol-phosphate aminotransferase protein TTC0060 218 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 46198385 Nonpathogen - ribonuclease P protein subunit TTC0077 1 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 46199333 Common rpsT 30S ribosomal protein S20 TTC1031 166 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 46199730 Common - hypothetical protein TTC1428 31 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 46199759 Common - proline iminopeptidase TTC1457 103 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 46199750 Common - ribosomal-protein-alanine acetyltransferase TTC1448 100 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 46198542 Common - hypothetical protein TTC0234 4 COG0388 COG0388, Predicted amidohydrolase General function prediction only 46198751 Common - (S)-2-hydroxy-acid oxidase chain D TTC0443 199 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 46198821 Common - aldehyde dehydrogenase TTC0513 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 46199007 Common ribD diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino) uracil reductase TTC0699 231 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 46198493 Common rplT 50S ribosomal protein L20 TTC0185 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 46198323 Nonpathogen - hypothetical protein TTC0015 1 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 46200117 Common - 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase TTC1815 196 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 46199556 Common - hypothetical protein TTC1254 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 46198618 Common - phosphoadenosine phosphosulfate reductase TTC0310 171 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 46199112 Common - amino acid ABC transporter, permease protein TTC0806 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 46198522 Common - transcriptional regulator TTC0214 16 COG4475 COG4475, Uncharacterized protein conserved in bacteria Function unknown 46199603 Common rpsD 30S ribosomal protein S4 TTC1301 245 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 46199520 Nonpathogen - transcriptional regulator TTC1218 7 None None None 46199691 Common - putative glycosyltransferase TTC1389 131 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 46199564 Nonpathogen - hypothetical protein TTC1262 1 COG3374 COG3374, Predicted membrane protein Function unknown 46199509 Common - hypothetical protein TTC1207 5 COG1569 COG1569, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 46200023 Common recF recF protein TTC1721 149 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 46200074 Common - predicted kinase TTC1772 50 COG1461 COG1461, Predicted kinase related to dihydroxyacetone kinase General function prediction only 46200208 Common argS arginyl-tRNA synthetase TTC1906 247 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 46199954 Common - histidinol-phosphatase TTC1652 37 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 46198890 Common - omega-(3) fatty acid desaturase TTC0582 39 COG3239 DesA, Fatty acid desaturase Lipid metabolism 46199788 Nonpathogen - hypothetical protein TTC1486 2 COG2976 COG2976, Uncharacterized protein conserved in bacteria Function unknown 46199826 Nonpathogen - hypothetical protein TTC1524 1 None None None 46200185 Nonpathogen - hypothetical protein TTC1883 1 None None None 46199663 Common phoR phosphate regulon sensor protein phoR TTC1361 223 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 46198470 Nonpathogen - hypothetical cytosolic protein TTC0162 4 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 46199931 Common malG maltose transport system permease protein malG TTC1629 132 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 46199525 Common - D-alanine-D-alanine ligase TTC1223 222 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 46198779 Common dsbA thiol:disulfide interchange protein dsbA TTC0471 93 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 46199479 Nonpathogen - hypothetical protein TTC1177 1 None None None 46198772 Nonpathogen - hypothetical protein TTC0464 1 None None None 46200201 Common - hypothetical conserved membrane associated protein TTC1899 26 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 46199312 Common - integral membrane protein/HD-hydrolase domain TTC1010 124 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 46199709 Common - S-layer protein TTC1407 22 COG5479 COG5479, Uncharacterized protein potentially involved in peptidoglycan biosynthesis Cell envelope biogenesis, outer membrane 46198845 Common cysS cysteinyl-tRNA synthetase TTC0537 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 46199972 Nonpathogen - hypothetical protein TTC1670 3 None None None 46198684 Common - carboxymethylenebutenolidase-related protein TTC0376 13 COG5153 CVT17, Putative lipase essential for disintegration of autophagic bodies inside the vacuole Intracellular trafficking and secretion / Lipid metabolism 46200158 Common - serine/threonine protein kinase TTC1856 184 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 46199420 Common - bacterioferritin TTC1118 63 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 161611241 Common aceE pyruvate dehydrogenase subunit E1 TTC1801 144 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 46199269 Common livH branched-chain amino acid transport system permease protein livH TTC0967 150 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 46200169 Common - tRNA (Guanosine-2'-O-)-methyltransferase TTC1867 208 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 46198834 Common - glycosyltransferase TTC0526 210 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 46198536 Common - isopentenyl-diphosphate delta-isomerase TTC0228 26 COG3044 COG3044, Predicted ATPase of the ABC class General function prediction only 46199376 Nonpathogen - probable sugar aminotransferase TTC1074 2 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 46198897 Common - mannosyl-3-phosphoglycerate phosphatase TTC0589 29 COG3769 COG3769, Predicted hydrolase (HAD superfamily) General function prediction only 46200224 Nonpathogen - hypothetical protein TTC1922 2 None None None 46199853 Common - probable undecaprenyl pyrophosphate synthetase TTC1551 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 46198764 Common - hypothetical membrane spanning protein TTC0456 104 COG0344 COG0344, Predicted membrane protein Function unknown 46199485 Nonpathogen - hypothetical protein TTC1183 1 None None None 46198967 Nonpathogen - hypothetical protein TTC0659 1 None None None 46199739 Common - transporter TTC1437 38 COG2860 COG2860, Predicted membrane protein Function unknown 46198507 Common - acylphosphatase TTC0199 147 COG1254 AcyP, Acylphosphatases Energy production and conversion 46199298 Nonpathogen - hypothetical protein TTC0996 1 None None None 46199817 Common phaN phaN TTC1515 29 COG3327 PaaX, Phenylacetic acid-responsive transcriptional repressor Transcription 46198333 Nonpathogen - hypothetical membrane spanning protein TTC0025 4 COG5652 COG5652, Predicted integral membrane protein Function unknown 46199619 Common rplX 50S ribosomal protein L24 TTC1317 210 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 46198404 Common - thioredoxin reductase TTC0096 247 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 46199612 Nonpathogen rpmD 50S ribosomal protein L30 TTC1310 5 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 46198790 Common - endonuclease IV TTC0482 99 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 46198422 Nonpathogen - hypothetical protein TTC0114 6 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 46199070 Common - agmatinase TTC0764 158 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 46199938 Common - cysteine synthase TTC1636 220 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 46198317 Common - sugar ABC transporter, permease protein TTC0009 143 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 46200176 Common era GTP-binding protein Era TTC1874 227 COG1159 Era, GTPase General function prediction only 46199864 Nonpathogen - hypothetical protein TTC1562 1 None None None 46200007 Common - hypothetical protein TTC1705 3 COG1724 COG1724, Predicted periplasmic or secreted lipoprotein Cell motility and secretion 46199628 Common rplW 50S ribosomal protein L23 TTC1326 150 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 46198581 Common - transposase TTC0273 14 COG5421 COG5421, Transposase DNA replication, recombination, and repair 46199914 Nonpathogen - hypothetical protein TTC1612 1 None None None 46198732 Common - dihydroorotate dehydrogenase 2 TTC0424 224 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 46198972 Common - hypothetical protein TTC0664 10 None None None 46199064 Common - biotin carboxylase TTC0758 235 COG0439 AccC, Biotin carboxylase Lipid metabolism 46199579 Common - arginine decarboxylase TTC1277 152 COG1166 SpeA, Arginine decarboxylase (spermidine biosynthesis) Amino acid transport and metabolism 46198438 Common - malate synthase TTC0130 68 COG2225 AceB, Malate synthase Energy production and conversion 46198605 Common prmA ribosomal protein L11 methyltransferase TTC0297 186 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 46198746 Common - hypothetical cytosolic protein TTC0438 155 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 46200289 Common - transporter TTC1987 78 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 46198787 Common - tRNA nucleotidyltransferase TTC0479 148 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 46199776 Nonpathogen - hypothetical cytosolic protein TTC1474 2 None None None 46198345 Nonpathogen - hypothetical protein TTC0037 1 None None None 46198942 Common - succinate-semialdehyde dehydrogenase TTC0634 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 46199474 Common - isocitrate dehydrogenase TTC1172 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 46198529 Common - leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein TTC0221 124 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 46198865 Common - dephospho-CoA kinase TTC0557 147 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 46198500 Nonpathogen - hypothetical protein TTC0192 6 COG1550 COG1550, Uncharacterized protein conserved in bacteria Function unknown 46200160 Common - LAO/AO transport system kinase TTC1858 99 COG1703 ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family Amino acid transport and metabolism 46199993 Common - 23S rRNA methyltransferase TTC1691 213 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 46199710 Common - acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha TTC1408 207 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 46199439 Common - putative hemolysin TTC1137 116 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 46200081 Common - NAD(P) transhydrogenase subunit alpha 2 TTC1779 114 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 46198593 Common - UDP-N-acetylglucosamine 2-epimerase TTC0285 154 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 46199566 Common - iron(III)-binding protein TTC1264 109 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 46198514 Common - hypothetical protein TTC0206 142 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 46198393 Common mntB manganese transport system membrane protein mntB TTC0085 68 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 46198375 Common - disulfide bond formation protein B TTC0067 21 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 46198938 Common - putative fructokinase TTC0630 47 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 46199979 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase TTC1677 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 46199032 Common ftsZ cell division protein FtsZ TTC0724 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 46199980 Common fabL enoyl-[acyl-carrier-protein] reductase (fabL) (NADPH) TTC1678 235 COG0623 FabI, Enoyl- acyl-carrier-protein 46199870 Common - rieske iron-sulfur protein TTC1568 24 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 46198600 Nonpathogen - hypothetical protein TTC0292 1 None None None 46198682 Common - aconitate hydratase TTC0374 223 COG1048 AcnA, Aconitase A Energy production and conversion 46199108 Nonpathogen - hypothetical protein TTC0802 1 None None None 46199077 Nonpathogen - hypothetical protein TTC0771 1 None None None 46199300 Common - sensory transduction histidine kinase TTC0998 178 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 46198415 Common - alpha-glucosidase/glycosyl hydrolase TTC0107 169 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 46199242 Nonpathogen - putative oxidoreductase TTC0940 2 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 46198607 Nonpathogen - hypothetical protein TTC0299 1 None None None 46198905 Common - leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein TTC0597 128 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 46198657 Common nusA transcription elongation factor NusA TTC0349 222 COG0195 NusA, Transcription elongation factor Transcription 46200192 Common - ABC transporter ATP-binding protein TTC1890 220 COG2401 COG2401, ABC-type ATPase fused to a predicted acetyltransferase domain General function prediction only 46199507 Common - deoxyhypusine synthase-like protein TTC1205 63 COG1899 DYS1, Deoxyhypusine synthase Posttranslational modification, protein turnover, chaperones 46199193 Nonpathogen - hypothetical protein TTC0889 1 None None None 46199908 Common - glucose inhibited division protein B TTC1606 189 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 46199740 Common - 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase TTC1438 181 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 46199585 Common - maltodextrin glucosidase TTC1283 148 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 46199099 Common - hypothetical protein TTC0793 91 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 46199584 Common mutS DNA mismatch repair protein mutS TTC1282 202 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 46199137 Nonpathogen - hypothetical protein TTC0831 5 COG2322 COG2322, Predicted membrane protein Function unknown 46199640 Nonpathogen - hypothetical protein TTC1338 1 None None None 46199606 Common rpmJ 50S ribosomal protein L36 TTC1304 140 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 46198413 Nonpathogen - hypothetical protein TTC0105 2 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 46200068 Common - hypoxanthine-guanine phosphoribosyltransferase TTC1766 150 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 46198342 Nonpathogen - hypothetical protein TTC0034 1 None None None 46199092 Nonpathogen - hypothetical protein TTC0786 1 None None None 46200102 Common lysR transcriptional regulatory protein, lysR family TTC1800 91 COG0583 LysR, Transcriptional regulator Transcription 46199516 Common - proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase TTC1214 86 COG0506 PutA, Proline dehydrogenase Amino acid transport and metabolism 46198505 Common - hypothetical protein TTC0197 76 COG1434 COG1434, Uncharacterized conserved protein Function unknown 46198324 Common - prolipoprotein diacylglyceryl transferase TTC0016 200 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 46199635 Common rpsL 30S ribosomal protein S12 TTC1333 240 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 46199879 Common prfA peptide chain release factor 1 TTC1577 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 46200253 Common recG ATP-dependent DNA helicase recG-related protein TTC1951 66 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 46199749 Common - transporter TTC1447 37 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 46198858 Common pgk phosphoglycerate kinase TTC0550 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 46199537 Common - hypothetical protein TTC1235 27 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 46198409 Common appD oligopeptide transport ATP-binding protein appD TTC0101 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 46200131 Common - NADH-dependent flavin oxidoreductase TTC1829 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 46198464 Nonpathogen - hypothetical protein TTC0156 2 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 46199796 Common - esterase TTC1494 53 COG0824 FcbC, Predicted thioesterase General function prediction only 46199613 Common rpsE 30S ribosomal protein S5 TTC1311 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 46199989 Nonpathogen - hypothetical protein TTC1687 1 None None None 46199178 Common potC spermidine/putrescine transport system permease protein potC TTC0874 113 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 46199081 Common - metal dependent hydrolase TTC0775 155 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 46199213 Nonpathogen - V-type ATP synthase subunit C TTC0909 12 COG1527 NtpC, Archaeal/vacuolar-type H+-ATPase subunit C Energy production and conversion 46199670 Nonpathogen - hypothetical membrane associated protein TTC1368 6 None None None 46199266 Common - 5'-nucleotidase TTC0964 142 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 46200229 Nonpathogen - hypothetical protein TTC1927 4 COG5551 COG5551, Uncharacterized conserved protein Function unknown 46199270 Common livM branched-chain amino acid transport system permease protein livM TTC0968 153 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 46199021 Common ftsI division specific D,D-transpeptidase/cell division protein ftsI TTC0713 206 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 46200178 Common - DNA integration/recombination/invertion protein TTC1876 43 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 46199296 Common - transcriptional regulator TTC0994 115 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 46200127 Common - leucyl-tRNA synthetase TTC1825 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 46200094 Common - tripartite transporter, small subunit TTC1792 73 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 46199689 Common - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase TTC1387 192 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 46198702 Common - 3-oxoacyl-[acyl-carrier protein] reductase TTC0394 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 46199594 Nonpathogen - hypothetical protein TTC1292 1 None None None 46198361 Nonpathogen - hypothetical protein TTC0053 3 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 46200099 Common - hypothetical protein TTC1797 66 COG1432 COG1432, Uncharacterized conserved protein Function unknown 46200261 Nonpathogen - probable nucleotidyltransferase TTC1959 1 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 46199340 Common ccmF cytochrome C-type biogenesis protein ccmF TTC1038 145 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 46200063 Common - biotin operon repressor/biotin-[acetyl-CoA-carboxylase] synthetase TTC1761 62 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 46198650 Common - acyl-CoA ligase TTC0342 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 46198926 Common - bacterioferritin TTC0618 103 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 46199129 Common - deoxyribose-phosphate aldolase TTC0823 99 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 46200138 Nonpathogen - hypothetical protein TTC1836 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 46199365 Nonpathogen - phosphoglucomutase/phosphomannomutase TTC1063 4 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 46200021 Common - soluble lytic murein transglycosylase and related regulatory proteins TTC1719 164 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 46200243 Nonpathogen - multidrug resistance protein, putative TTC1941 1 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 46199160 Nonpathogen - prepilin-like protein TTC0856 1 COG4966 PilW, Tfp pilus assembly protein PilW Cell motility and secretion / Intracellular trafficking and secretion 46199011 Common - xaa-pro aminopeptidase TTC0703 248 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 46199550 Nonpathogen - hydrolase family protein TTC1248 2 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 46199493 Common - ribonuclease H TTC1191 175 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 46198749 Common - hypothetical protein TTC0441 94 COG2947 COG2947, Uncharacterized conserved protein Function unknown 46199293 Common - divalent cation tolerance protein TTC0991 118 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 46199386 Common tatD sec-independent protein tatD TTC1084 235 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 46199807 Common rbsC ribose transport system permease protein rbsC TTC1505 108 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 46198609 Common - short chain dehydrogenase TTC0301 235 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 46198879 Nonpathogen - probable transposase TTC0571 7 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 46199155 Common - acetolactate synthase small subunit TTC0851 193 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 46199413 Common - periplasmic serine protease TTC1111 45 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 46199666 Nonpathogen - hypothetical protein TTC1364 5 None None None 46199727 Nonpathogen secG preprotein translocase subunit SecG TTC1425 1 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 46198947 Nonpathogen - hypothetical protein TTC0639 1 COG3857 AddB, ATP-dependent nuclease, subunit B DNA replication, recombination, and repair 46198448 Common - hypothetical protein TTC0140 13 None None None 46199576 Common - ribose-phosphate pyrophosphokinase TTC1274 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 46198661 Common smtB transcriptional repressor smtB TTC0353 113 COG0640 ArsR, Predicted transcriptional regulators Transcription 46198819 Common mutT phosphohydrolase (mutT/nudix family protein) TTC0511 40 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 46199228 Common - hypothetical membrane spanning protein TTC0924 14 COG5438 COG5438, Predicted multitransmembrane protein Function unknown 46199177 Common - spermidine/putrescine-binding protein TTC0873 128 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 46199442 Common - hypothetical protein TTC1140 21 COG3877 COG3877, Uncharacterized protein conserved in bacteria Function unknown 46198622 Nonpathogen - hypothetical protein TTC0314 1 None None None 46198648 Common - putative hydrolase TTC0340 143 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 46199883 Common - hypothetical protein TTC1581 106 COG0393 COG0393, Uncharacterized conserved protein Function unknown 46198484 Nonpathogen - hypothetical protein TTC0176 1 None None None 46198639 Common - 3-hydroxyacyl-Coa dehydrogenase TTC0331 231 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 46199028 Common - UDP-N-acetylmuramate-alanine ligase TTC0720 207 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 46199767 Common - hypothetical protein TTC1465 76 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 46200222 Common - NADH-quinone oxidoreductase chain A TTC1920 156 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 46199765 Common - (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase TTC1463 186 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 46198421 Common - hypothetical protein TTC0113 37 COG3744 COG3744, Uncharacterized protein conserved in bacteria Function unknown 46199901 Nonpathogen - hypothetical protein TTC1599 1 None None None 46200032 Common - ferric uptake regulation protein TTC1730 184 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 46200212 Common - NADH-quinone oxidoreductase chain K TTC1910 30 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 46199752 Nonpathogen - hypothetical protein TTC1450 1 None None None 46199145 Common - hypothetical cytosolic protein TTC0839 63 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 46199876 Common - florfenicol resistance protein TTC1574 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 46199956 Common - DNA-3-methyladenine glycosylase II TTC1654 61 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 46200135 Common - quinone oxidoreductase TTC1833 178 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 46199842 Common - hypothetical protein TTC1540 35 COG1543 COG1543, Uncharacterized conserved protein Function unknown 46198760 Common - biotin synthase/thiamine biosynthesis enzyme TTC0452 81 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 46198899 Common - dihydrodipicolinate synthase TTC0591 232 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 46200012 Common - glucose-6-phosphate isomerase TTC1710 190 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 46198912 Common paaZ bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase TTC0604 216 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 46199102 Nonpathogen - hypothetical protein TTC0796 1 None None None 46198753 Common - hypothetical protein TTC0445 8 None None None 46199734 Common - transposase TTC1432 82 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 46200148 Nonpathogen - hypothetical protein TTC1846 1 None None None 46199732 Common - hypothetical protein TTC1430 7 COG0433 COG0433, Predicted ATPase General function prediction only 46199005 Common ribA GTP cyclohydrolase II/3,4-dihydroxy-2-butanone-4-phosphate synthase TTC0697 232 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 46198629 Common - phosphomethylpyrimidine kinase/hydroxymethylpyrimidine kinase TTC0321 217 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 46198424 Common - hypothetical cytosolic protein TTC0116 12 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 46199558 Common - putative aminotransferase B TTC1256 236 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 46199781 Nonpathogen - hypothetical protein TTC1479 1 None None None 46199527 Common - 50S ribosomal protein L25/general stress protein Ctc TTC1225 166 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 46198560 Common - nicotinate phosphoribosyltransferase TTC0252 100 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 46198616 Common - uroporphyrin-III C-methyltransferase TTC0308 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 46198457 Common - glycine cleavage system H protein TTC0149 183 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 46199358 Common soxY soxY protein TTC1056 39 COG5501 COG5501, Predicted secreted protein Function unknown 46199374 Common - transcription regulator, crp family TTC1072 150 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 46198870 Common trmE tRNA modification GTPase TrmE TTC0562 221 COG0486 ThdF, Predicted GTPase General function prediction only 46200238 Common - tungstate-binding protein precursor TTC1936 62 COG2998 TupB, ABC-type tungstate transport system, permease component Coenzyme metabolism 46198792 Common - putative transferase/hydrolase TTC0484 197 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 46199809 Common - flavoredoxin TTC1507 49 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 46200041 Common rplA 50S ribosomal protein L1 TTC1739 228 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 46200272 Common - hypothetical protein TTC1970 16 COG3369 COG3369, Uncharacterized conserved protein Function unknown 46199268 Common - leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein TTC0966 137 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 46198849 Common - hypothetical protein TTC0541 10 COG3809 COG3809, Uncharacterized protein conserved in bacteria Function unknown 46199578 Nonpathogen - hypothetical protein TTC1276 1 COG1801 COG1801, Uncharacterized conserved protein Function unknown 46199163 Common - hypothetical protein TTC0859 22 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 46199458 Common - amidophosphoribosyltransferase TTC1156 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 46200187 Common - hypothetical protein TTC1885 7 None None None 46199159 Nonpathogen - prepilin-like protein TTC0855 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 46200025 Common pstB phosphate transport ATP-binding protein pstB TTC1723 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 46199234 Nonpathogen - hypothetical protein TTC0930 1 None None None 46199253 Common - immunogenic protein TTC0951 83 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 46199480 Nonpathogen - hypothetical protein TTC1178 1 None None None 46199547 Nonpathogen - hypothetical protein TTC1245 1 COG1430 COG1430, Uncharacterized conserved protein Function unknown 46198744 Common - acetyltransferase TTC0436 13 COG0456 RimI, Acetyltransferases General function prediction only 46198954 Nonpathogen - hypothetical protein TTC0646 2 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 46199338 Common ccmH cytochrome C-type biogenesis protein ccmH TTC1036 89 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 46199949 Common - 6,7-dimethyl-8-ribityllumazine synthase TTC1647 228 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 46199015 Common - translation initiation factor aIF-2B alpha subunit TTC0707 128 COG0182 COG0182, Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 46198598 Nonpathogen - transposase TTC0290 8 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 46198516 Common - pyruvyl-transferase TTC0208 25 COG2327 WcaK, Uncharacterized conserved protein Function unknown 46198988 Common greA anti-cleavage anti-greA transcription factor gfh1 TTC0680 179 COG0782 GreA, Transcription elongation factor Transcription 46199203 Common - hypothetical membrane spanning protein TTC0899 21 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 46200174 Common - pseudocatalase TTC1872 46 COG3546 COG3546, Mn-containing catalase Inorganic ion transport and metabolism 46199964 Common - polypeptide deformylase, fms protein-like protein TTC1662 212 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 46199037 Common trpA tryptophan synthase subunit alpha TTC0729 216 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 46198769 Common - DNA polymerase III epsilon chain-like protein TTC0461 174 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 46199351 Common - putative sulfurtransferase TTC1049 123 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 46199069 Common - putative hydrolase TTC0763 58 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 46198588 Common - lipopolysaccharide N-acetylglucosaminyltransferase TTC0280 18 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 46199305 Common - signal peptidase I TTC1003 129 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 46199698 Common - acetyl-lysine deacetylase TTC1396 133 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 46198713 Nonpathogen - hypothetical protein TTC0405 1 None None None 46199677 Nonpathogen - hypothetical protein TTC1375 1 None None None 46198363 Nonpathogen - hypothetical protein TTC0055 1 COG2045 COG2045, Phosphosulfolactate phosphohydrolase and related enzymes Coenzyme metabolism / General function prediction only 46198498 Common fumC fumarate hydratase TTC0190 232 COG0114 FumC, Fumarase Energy production and conversion 46198766 Common - metallo-beta-lactamase protein TTC0458 108 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 46199405 Common - ATP-dependent protease subunit-like protein TTC1103 89 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 46198347 Common - 3-methyl-2-oxobutanoate hydroxymethyltransferase TTC0039 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 46198319 Common - sugar ABC transporter, periplasmic sugar-binding protein, putative TTC0011 109 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 46199023 Nonpathogen - hypothetical protein TTC0715 1 None None None 46199904 Common comE competence protein/comEA-related protein TTC1602 57 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 46199991 Nonpathogen - hypothetical protein TTC1689 2 None None None 46199391 Common sdhB succinate dehydrogenase iron-sulfur subunit TTC1089 207 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 46198840 Common degV degV protein TTC0532 52 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 46198604 Common - probable transcriptional regulator TTC0296 19 COG2345 COG2345, Predicted transcriptional regulator Transcription 46200111 Common - ferredoxin TTC1809 157 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 46200287 Nonpathogen - hypothetical protein TTC1985 1 None None None 46199049 Nonpathogen - hypothetical protein TTC0743 2 None None None 46199437 Common moxR moxR-like ATPase TTC1135 172 COG0714 COG0714, MoxR-like ATPases General function prediction only 46199601 Common rplQ 50S ribosomal protein L17 TTC1299 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 46199774 Nonpathogen - hypothetical protein TTC1472 1 None None None 46200084 Common - permease TTC1782 26 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 46200141 Nonpathogen - general secretion pathway protein G TTC1839 1 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 46199772 Nonpathogen - hypothetical protein TTC1470 2 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 46198575 Nonpathogen - hypothetical protein TTC0267 15 COG2250 COG2250, Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN Function unknown 46200162 Common - hypothetical protein TTC1860 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 46198944 Common - exopolyphosphatase TTC0636 180 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 46199754 Common - acyl-CoA hydrolase TTC1452 123 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 46199277 Common - folylpolyglutamate synthase/dihydrofolate synthase TTC0975 213 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 46198642 Common livF branched-chain amino acid transport ATP-binding protein livF TTC0334 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 46199725 Common rpmA 50S ribosomal protein L27 TTC1423 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 46198338 Nonpathogen - hypothetical membrane spanning protein TTC0030 1 COG0795 COG0795, Predicted permeases General function prediction only 46199331 Nonpathogen - hypothetical protein TTC1029 4 None None None 46199318 Nonpathogen pilW competence protein pilW TTC1016 2 COG5373 COG5373, Predicted membrane protein Function unknown 46199062 Common - N utilization substance protein B-like protein TTC0756 109 COG0781 NusB, Transcription termination factor Transcription 46198486 Common - hemolysin TTC0178 132 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 46198553 Common - hypothetical protein TTC0245 57 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 161611243 Common rplM 50S ribosomal protein L13 TTC1101 233 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 46198739 Common - glycerate dehydrogenase/glyoxylate reductase TTC0431 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 46198452 Common - NADP-dependent malic enzyme TTC0144 196 COG0281 SfcA, Malic enzyme Energy production and conversion 46199290 Common - putative tRNA (uracil-5-)-methyltransferase TTC0988 197 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 46199054 Common - L-lactate dehydrogenase TTC0748 155 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 46198371 Common - sugar kinase TTC0063 133 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 46200203 Common - 2-nitropropane dioxygenase TTC1901 128 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 46198527 Common livF branched-chain amino acid transport ATP-binding protein livF TTC0219 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 46199643 Common - carboxylesterase TTC1341 24 COG1647 COG1647, Esterase/lipase General function prediction only 46200248 Nonpathogen - hypothetical protein TTC1946 1 None None None 46199315 Common pilM pilus-associated protein pilM TTC1013 80 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 46198472 Common rpoD RNA polymerase sigma factor rpoD TTC0164 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 46200282 Common - glycogen synthase TTC1980 180 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 46199040 Common - NAD-dependent DNA ligase TTC0732 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 46198378 Common - glutamyl-tRNA synthetase TTC0070 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 46199282 Common - mannose-6-phosphate isomerase TTC0980 47 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 46198686 Nonpathogen - hypothetical membrane spanning protein TTC0378 5 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 46199933 Common - hypothetical protein TTC1631 11 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 46199244 Common - hypothetical protein TTC0942 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 46199469 Common - hypothetical protein TTC1167 87 COG0585 COG0585, Uncharacterized conserved protein Function unknown 46198832 Common - hypothetical protein TTC0524 86 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 46198671 Common - ABC transporter ATP-binding protein TTC0363 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 46199082 Common pacL putative cation-transporting ATPase pacL TTC0776 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 46198770 Common - transcriptional regulator TTC0462 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 46198406 Common appA oligopeptide-binding protein appA TTC0098 206 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 46198931 Common - beta-ketoadipyl CoA thiolase TTC0623 187 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 46198331 Common - putative FAD-binding dehydrogenase TTC0023 32 COG3573 COG3573, Predicted oxidoreductase General function prediction only 46200118 Common - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase TTC1816 159 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 46198828 Common - seryl-tRNA synthetase TTC0520 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 46198776 Common - RNA polymerase sigma-32 factor TTC0468 43 COG4327 COG4327, Predicted membrane protein Function unknown 46199719 Nonpathogen - hypothetical protein TTC1417 1 None None None 46199641 Common - Na(+)-linked D-alanine glycine permease TTC1339 112 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 46198851 Common - chromosome partition protein smc TTC0543 168 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 46199464 Common - hydroxymethylglutaryl-CoA lyase TTC1162 88 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 46198460 Common - hypothetical protein TTC0152 169 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 46198805 Nonpathogen - hypothetical protein TTC0497 2 COG5637 COG5637, Predicted integral membrane protein Function unknown 46199987 Nonpathogen - hypothetical protein TTC1685 1 None None None 46199169 Common - isopropylmalate isomerase large subunit TTC0865 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 46199094 Common - aminopeptidase TTC0788 56 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 46200205 Common tetR transcriptional regulator, tetR family TTC1903 80 COG1309 AcrR, Transcriptional regulator Transcription 46198503 Common ylmE ylmE TTC0195 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 46199855 Common - 3-octaprenyl-4-hydroxybenzoate carboxy-lyase TTC1553 151 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 46199100 Common - hypothetical membrane spanning protein TTC0794 65 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 46199615 Common rplF 50S ribosomal protein L6 TTC1313 226 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 46198856 Nonpathogen bioY probable bioY protein TTC0548 14 COG1268 BioY, Uncharacterized conserved protein General function prediction only 46199794 Common - anthranilate synthase component II/para-aminobenzoate synthase glutamine amidotransferase component II TTC1492 232 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 46199052 Common - ATP-dependent protease La TTC0746 204 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 46199039 Common thyX FAD-dependent thymidylate synthase TTC0731 57 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 46198673 Common - molybdate-binding protein TTC0365 133 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 46200037 Common rpmG 50S ribosomal protein L33 TTC1735 116 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 46198867 Common - methyltransferase TTC0559 193 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 46199423 Nonpathogen - hypothetical protein TTC1121 5 COG1503 eRF1, Peptide chain release factor 1 (eRF1) Translation, ribosomal structure and biogenesis 46199629 Common rplD 50S ribosomal protein L4 TTC1327 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 46200050 Nonpathogen - hypothetical protein TTC1748 1 None None None 46198709 Nonpathogen - hypothetical protein TTC0401 1 None None None 46199658 Common - heavy metal binding protein TTC1356 106 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 46199360 Common - cytochrome c-552 precursor TTC1058 42 COG3258 COG3258, Cytochrome c Energy production and conversion 46198467 Common - riboflavin kinase/FMN adenylyltransferase TTC0159 211 COG0196 RibF, FAD synthase Coenzyme metabolism 46198996 Common - shikimate 5-dehydrogenase TTC0688 223 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 46198377 Nonpathogen - hypothetical protein TTC0069 1 None None None 46199700 Nonpathogen - hypothetical protein TTC1398 1 COG2427 COG2427, Uncharacterized conserved protein Function unknown 46199384 Common - alanine dehydrogenase TTC1082 166 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 46198391 Common livF branched-chain amino acid transport ATP-binding protein livF TTC0083 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 46200009 Common - formate-tetrahydrofolate ligase TTC1707 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 46198970 Nonpathogen - hypothetical protein TTC0662 1 None None None 46198543 Common - gluconate 5-dehydrogenase TTC0235 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 46198579 Common - hypothetical cytosolic protein TTC0271 21 COG4867 COG4867, Uncharacterized protein with a von Willebrand factor type A (vWA) domain General function prediction only 46199505 Common - hypothetical protein TTC1203 39 COG2107 COG2107, Predicted periplasmic solute-binding protein General function prediction only 46199935 Nonpathogen - hypothetical protein TTC1633 2 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 46198519 Common - sugar-binding transport ATP-binding protein TTC0211 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 46199302 Common - hypothetical protein TTC1000 137 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 46199079 Common rpsO 30S ribosomal protein S15 TTC0773 214 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 46198880 Common - probable transposase TTC0572 40 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 46198655 Common infB translation initiation factor IF-2 TTC0347 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 46198956 Common - ABC transporter ATP-binding protein TTC0648 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 46199047 Nonpathogen - hypothetical protein TTC0741 1 None None None 46199194 Nonpathogen - Fe-S binding reductase, putative TTC0890 2 None None None 46198619 Common - uroporphyrin-III C-methyltransferase/precorrin-2 oxidase/ferrochelatase TTC0311 141 COG1648 CysG, Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) Coenzyme metabolism 46199279 Common - multidrug resistance ABC transporter ATP-binding and permease protein TTC0977 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 46198903 Common - probable oxidoreductase TTC0595 94 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 46198550 Common - biotin synthase TTC0242 176 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 46199257 Nonpathogen - hypothetical protein TTC0955 1 COG0456 RimI, Acetyltransferases General function prediction only 46200245 Nonpathogen - hypothetical protein TTC1943 1 None None None 46198810 Common - glycosyltransferase TTC0502 30 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 46199926 Common - hypothetical cytosolic protein TTC1624 175 COG1496 COG1496, Uncharacterized conserved protein Function unknown 46198446 Common - phosphoribosylaminoimidazole carboxylase catalytic subunit TTC0138 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 46199587 Common - nucleotidyltransferase TTC1285 57 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 46199495 Common marC multiple antibiotic resistance protein marC TTC1193 157 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 46199487 Common - putative nucleosidase TTC1185 61 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 46198877 Common - pyruvate decarboxylase alpha subunit-like protein TTC0569 155 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 46199599 Common - transporter TTC1297 39 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 46198663 Common - pyridoxine biosynthesis amidotransferase TTC0355 85 COG0311 PDX2, Predicted glutamine amidotransferase involved in pyridoxine biosynthesis Coenzyme metabolism 46199919 Nonpathogen - hypothetical protein TTC1617 1 None None None 46199419 Common - thioredoxin TTC1117 235 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 46198965 Common - hypothetical protein TTC0657 7 None None None 46199580 Common - diguanylate cyclase/phosphodiesterase domain 1 (GGDEF) TTC1278 175 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 46198624 Nonpathogen thiS putative thiS protein TTC0316 3 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 46199833 Common - excinuclease ABC subunit B TTC1531 224 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 46199814 Nonpathogen - hypothetical protein TTC1512 1 None None None 46199539 Nonpathogen - hypothetical protein TTC1237 1 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 46200217 Common - NADH-quinone oxidoreductase chain F TTC1915 169 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 46199885 Common mazG nucleoside triphosphate pyrophosphohydrolase TTC1583 154 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 46198817 Common rpsB 30S ribosomal protein S2 TTC0509 246 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 46200064 Common - glucose-1-phosphate thymidylyltransferase TTC1762 236 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 46200059 Common - 2-oxoisovalerate dehydrogenase alpha subunit TTC1757 154 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 46199894 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit beta TTC1592 107 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 46198979 Common rimM 16S rRNA processing protein rimM TTC0671 137 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 46200096 Nonpathogen - universal stress protein family TTC1794 5 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 46199912 Common - enolase TTC1610 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 46199769 Common - 2'-5' RNA ligase TTC1467 74 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 46198949 Common - hypothetical protein TTC0641 14 COG3656 COG3656, Predicted periplasmic protein Function unknown 46198434 Nonpathogen - hypothetical protein TTC0126 1 COG4423 COG4423, Uncharacterized protein conserved in bacteria Function unknown 46199342 Nonpathogen - hypothetical protein TTC1040 1 None None None 46200034 Nonpathogen - hypothetical protein TTC1732 1 None None None 46200227 Nonpathogen - hypothetical protein TTC1925 1 None None None 46198665 Common - hydrolase (HAD superfamily) TTC0357 94 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 46199856 Nonpathogen - hypothetical membrane associated protein TTC1554 8 None None None 46198309 Common - hypothetical protein TTC0001 10 None None None 46199367 Common - long-chain-fatty-acid-CoA ligase TTC1065 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 46199893 Common - 2-oxoacid-ferredoxin oxidoreductase TTC1591 106 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 46199906 Common parB chromosome partitioning protein parB TTC1604 189 COG1475 Spo0J, Predicted transcriptional regulators Transcription 46200220 Common - NADH-quinone oxidoreductase chain C TTC1918 181 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 46198591 Common - hypothetical protein TTC0283 12 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 46199356 Common - putative cytochrome c precursor TTC1054 31 COG3258 COG3258, Cytochrome c Energy production and conversion 46199276 Nonpathogen - hypothetical protein TTC0974 6 None None None 46200043 Common - single-strand DNA binding protein (SSB) TTC1741 189 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 46198700 Common fecE iron(III) dicitrate transport ATP-binding protein fecE TTC0392 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 46199410 Common - Na(+)/H(+) antiporter TTC1108 207 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 46198725 Common - protease Do TTC0417 199 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 46198562 Common - hypothetical protein TTC0254 9 None None None 46199215 Nonpathogen - V-type sodium ATP synthase subunit K Homolog TTC0911 1 None None None 46199867 Common - hypothetical protein TTC1565 4 None None None 46199518 Common - transposase TTC1216 11 None None None 46198928 Common - quinolinate synthetase TTC0620 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 46199135 Nonpathogen - hypothetical protein TTC0829 1 None None None 46198909 Common - probable phenylacetic acid degradation protein TTC0601 57 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 46200125 Common - ATP/GTP hydrolase TTC1823 182 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 46199668 Common - phosphatidylethanolamine N-methyltransferase TTC1366 73 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 46198326 Common tatA Sec-independent protein translocase protein tatA TTC0018 20 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 46198689 Common marR transcriptional regulator, marR family TTC0381 2 COG1846 MarR, Transcriptional regulators Transcription 46199189 Common - acetyl-coenzyme A synthetase TTC0885 205 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 46199255 Common - immunogenic protein TTC0953 77 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 46199123 Common - two-component system histidine kinase TTC0817 151 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 46199860 Common - sodium export permease protein TTC1558 5 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 46198900 Common - 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase TTC0592 180 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 46199522 Common - modification methylase TTC1220 12 COG1041 COG1041, Predicted DNA modification methylase DNA replication, recombination, and repair